LOCUS       DAUGUF010000001        94111 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUGUF010000001 DAUGUF010000000
VERSION     DAUGUF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 94111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94111
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.001"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            14..193
                     /locus_tag="VIB71_000001"
     CDS             14..193
                     /locus_tag="VIB71_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ8821767.1"
                     /translation="MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGE
                     VVTDEKVEEVLMELE"
     gene            438..974
                     /gene="rimP"
                     /locus_tag="VIB71_000002"
     CDS             438..974
                     /gene="rimP"
                     /locus_tag="VIB71_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEQ8821768.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            1149..2306
                     /gene="nusA"
                     /locus_tag="VIB71_000003"
     CDS             1149..2306
                     /gene="nusA"
                     /locus_tag="VIB71_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEQ8821769.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATAVEEPVVDDVMTAEEV"
     gene            2322..2618
                     /locus_tag="VIB71_000004"
     CDS             2322..2618
                     /locus_tag="VIB71_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEQ8821770.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            2611..2913
                     /locus_tag="VIB71_000005"
     CDS             2611..2913
                     /locus_tag="VIB71_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEQ8821771.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            2933..5794
                     /gene="infB"
                     /locus_tag="VIB71_000006"
     CDS             2933..5794
                     /gene="infB"
                     /locus_tag="VIB71_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEQ8821772.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            6000..6350
                     /gene="rbfA"
                     /locus_tag="VIB71_000007"
     CDS             6000..6350
                     /gene="rbfA"
                     /locus_tag="VIB71_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEQ8821773.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELDNKS"
     gene            complement(6481..7470)
                     /locus_tag="VIB71_000008"
     CDS             complement(6481..7470)
                     /locus_tag="VIB71_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8821774.1"
                     /translation="MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNIFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEI
                     PNYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTPQ"
     gene            7642..8076
                     /locus_tag="VIB71_000009"
     CDS             7642..8076
                     /locus_tag="VIB71_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEQ8821775.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNLLTSYREGRAYIYQALLDETLVQKEALATVLDGICQRQHTRLLLERLYDL
                     PMTLEEIEAFQELLEVKKENAVLEVPCNCLPGQCHCQKKETY"
     gene            8076..10307
                     /locus_tag="VIB71_000010"
     CDS             8076..10307
                     /locus_tag="VIB71_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEQ8821776.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPSFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGQAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATDVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTVTEGKPSLQKLLI
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEQFESLTGLGVTGQLEG
                     RRLAIGNATLMAILGIDLSCVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALQQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGK
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMRSDMLDLVKVMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            10321..10524
                     /locus_tag="VIB71_000011"
     CDS             10321..10524
                     /locus_tag="VIB71_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEQ8821777.1"
                     /translation="MEKHYQVTGMTCDGCVRTVTEKLSAVPGVQSVQVNLEKGQAKVT
                     GRPLTFLLKRALKDTKFELHQSS"
     gene            complement(10724..11494)
                     /locus_tag="VIB71_000012"
     CDS             complement(10724..11494)
                     /locus_tag="VIB71_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8821778.1"
                     /translation="MLKRERLLKITEIVNKQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFV
                     FYHLDNIDAVVTDSQITEEVIERYSQFTQLLVAHENKE"
     gene            11731..12204
                     /locus_tag="VIB71_000013"
     CDS             11731..12204
                     /locus_tag="VIB71_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8821779.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREVV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            12197..12502
                     /locus_tag="VIB71_000014"
     CDS             12197..12502
                     /locus_tag="VIB71_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8821780.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIESQMTDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFDLPIPIVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            12528..13979
                     /locus_tag="VIB71_000015"
     CDS             12528..13979
                     /locus_tag="VIB71_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEQ8821781.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYAARNHLPVFVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGASAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMT"
     gene            14237..14662
                     /gene="lacA"
                     /locus_tag="VIB71_000016"
     CDS             14237..14662
                     /gene="lacA"
                     /locus_tag="VIB71_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8821782.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEESYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGPELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            14677..15093
                     /locus_tag="VIB71_000017"
     CDS             14677..15093
                     /locus_tag="VIB71_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ8821783.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTGVGINNAVNK
                     VPGIRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDIIDAFIKAEYKETEENK
                     KLIAKIAHLETHHASQEDPDFFTEFLERWDRGEYHD"
     gene            15103..15545
                     /locus_tag="VIB71_000018"
                     /pseudo
     CDS             15103..15545
                     /locus_tag="VIB71_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            15592..16569
                     /gene="lacD"
                     /locus_tag="VIB71_000019"
     CDS             15592..16569
                     /gene="lacD"
                     /locus_tag="VIB71_000019"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8821784.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            16766..17383
                     /locus_tag="VIB71_000020"
     CDS             16766..17383
                     /locus_tag="VIB71_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEQ8821785.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            17385..18209
                     /locus_tag="VIB71_000021"
     CDS             17385..18209
                     /locus_tag="VIB71_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8821786.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(18245..18802)
                     /locus_tag="VIB71_000022"
     CDS             complement(18245..18802)
                     /locus_tag="VIB71_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8821787.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLEIKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            19095..19937
                     /locus_tag="VIB71_000023"
     CDS             19095..19937
                     /locus_tag="VIB71_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8821788.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            complement(20066..20788)
                     /locus_tag="VIB71_000024"
     CDS             complement(20066..20788)
                     /locus_tag="VIB71_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821789.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSYP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            20990..22621
                     /locus_tag="VIB71_000025"
     CDS             20990..22621
                     /locus_tag="VIB71_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEQ8821790.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADDKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            22739..23887
                     /gene="nagA"
                     /locus_tag="VIB71_000026"
     CDS             22739..23887
                     /gene="nagA"
                     /locus_tag="VIB71_000026"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEQ8821791.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLSLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEKYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            24009..24848
                     /locus_tag="VIB71_000027"
     CDS             24009..24848
                     /locus_tag="VIB71_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEQ8821792.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQAALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTPEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            24980..25513
                     /locus_tag="VIB71_000028"
     CDS             24980..25513
                     /locus_tag="VIB71_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEQ8821793.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            25885..26802
                     /gene="glyQ"
                     /locus_tag="VIB71_000029"
     CDS             25885..26802
                     /gene="glyQ"
                     /locus_tag="VIB71_000029"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8821794.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGLPLLDEATRAILLAEDDE"
     gene            27180..29219
                     /locus_tag="VIB71_000030"
     CDS             27180..29219
                     /locus_tag="VIB71_000030"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEQ8821795.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQCVIVDAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGNFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGVV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYTNKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAVAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQALKNNRVAILSDLVSKAKTIAAFNQLNTK"
     gene            29373..29630
                     /locus_tag="VIB71_000031"
     CDS             29373..29630
                     /locus_tag="VIB71_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEQ8821796.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            29757..30149
                     /locus_tag="VIB71_000032"
     CDS             29757..30149
                     /locus_tag="VIB71_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEQ8821797.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            30509..32035
                     /gene="glpK"
                     /locus_tag="VIB71_000033"
     CDS             30509..32035
                     /gene="glpK"
                     /locus_tag="VIB71_000033"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEQ8821798.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            32051..33889
                     /gene="glpO"
                     /locus_tag="VIB71_000034"
     CDS             32051..33889
                     /gene="glpO"
                     /locus_tag="VIB71_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEQ8821799.1"
                     /translation="MEFSKETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALVASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFNHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQQEG"
     gene            33891..34592
                     /locus_tag="VIB71_000035"
     CDS             33891..34592
                     /locus_tag="VIB71_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8821800.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            34701..36047
                     /locus_tag="VIB71_000036"
     CDS             34701..36047
                     /locus_tag="VIB71_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8821801.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDGDLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            36037..37536
                     /locus_tag="VIB71_000037"
     CDS             36037..37536
                     /locus_tag="VIB71_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8821802.1"
                     /translation="MKIEDLMDKERKAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYLEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILALLVFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVYLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            37662..38306
                     /gene="fsa"
                     /locus_tag="VIB71_000038"
     CDS             37662..38306
                     /gene="fsa"
                     /locus_tag="VIB71_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8821803.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            38524..40509
                     /gene="tkt"
                     /locus_tag="VIB71_000039"
     CDS             38524..40509
                     /gene="tkt"
                     /locus_tag="VIB71_000039"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEQ8821804.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWASKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAVYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNFNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            40702..40968
                     /locus_tag="VIB71_000040"
     CDS             40702..40968
                     /locus_tag="VIB71_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8821805.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            41002..41736
                     /locus_tag="VIB71_000041"
     CDS             41002..41736
                     /locus_tag="VIB71_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8821806.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            41741..43369
                     /locus_tag="VIB71_000042"
     CDS             41741..43369
                     /locus_tag="VIB71_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8821807.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQENHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVIQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLTQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGNGQWLTMGLIFGNLIVTGVVGFGAVIIANIIQQ
                     PLLISILLSCLTLMVLGIAHLWIQKTFWKSLEKL"
     gene            43433..44254
                     /gene="proB"
                     /locus_tag="VIB71_000043"
     CDS             43433..44254
                     /gene="proB"
                     /locus_tag="VIB71_000043"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEQ8821808.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            44247..45497
                     /locus_tag="VIB71_000044"
     CDS             44247..45497
                     /locus_tag="VIB71_000044"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEQ8821809.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATNIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     HTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMDLEALTSTKFYINGDGHIRE"
     gene            45517..45738
                     /locus_tag="VIB71_000045"
     CDS             45517..45738
                     /locus_tag="VIB71_000045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821810.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFDLFGDGM
                     LVSWIKRRKMSKVNQLLIDLQVTLQNCRR"
     gene            45781..45945
                     /locus_tag="VIB71_000046"
     CDS             45781..45945
                     /locus_tag="VIB71_000046"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821811.1"
                     /translation="MSWDKIFDIWLDNLLTDCCVIKEAKNFLQVVEILEAAAKSVLAK
                     LADSEQKEQD"
     gene            45969..46982
                     /gene="rsmH"
                     /locus_tag="VIB71_000047"
     CDS             45969..46982
                     /gene="rsmH"
                     /locus_tag="VIB71_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEQ8821812.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            46987..47310
                     /gene="ftsL"
                     /locus_tag="VIB71_000048"
     CDS             46987..47310
                     /gene="ftsL"
                     /locus_tag="VIB71_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEQ8821813.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            47314..49569
                     /locus_tag="VIB71_000049"
     CDS             47314..49569
                     /locus_tag="VIB71_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8821814.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            49571..50581
                     /locus_tag="VIB71_000050"
     CDS             49571..50581
                     /locus_tag="VIB71_000050"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEQ8821815.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            50739..52082
                     /locus_tag="VIB71_000051"
     CDS             50739..52082
                     /locus_tag="VIB71_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8821816.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            52277..53080
                     /locus_tag="VIB71_000052"
     CDS             52277..53080
                     /locus_tag="VIB71_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8821817.1"
                     /translation="MTSVFLTSGWAFYDYLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            53080..53823
                     /locus_tag="VIB71_000053"
     CDS             53080..53823
                     /locus_tag="VIB71_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8821818.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            53927..54151
                     /locus_tag="VIB71_000054"
     CDS             53927..54151
                     /locus_tag="VIB71_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEQ8821819.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            54215..55132
                     /gene="trxB"
                     /locus_tag="VIB71_000055"
     CDS             54215..55132
                     /gene="trxB"
                     /locus_tag="VIB71_000055"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEQ8821820.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDQEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            55301..56680
                     /locus_tag="VIB71_000056"
     CDS             55301..56680
                     /locus_tag="VIB71_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8821821.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            56851..58305
                     /locus_tag="VIB71_000057"
     CDS             56851..58305
                     /locus_tag="VIB71_000057"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEQ8821822.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPGNFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKTYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMTLIDNIRKDTHGKSE"
     gene            58307..59131
                     /gene="nadE"
                     /locus_tag="VIB71_000058"
     CDS             58307..59131
                     /gene="nadE"
                     /locus_tag="VIB71_000058"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEQ8821823.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETSDKAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKAAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            59316..60653
                     /gene="pepC"
                     /locus_tag="VIB71_000059"
     CDS             59316..60653
                     /gene="pepC"
                     /locus_tag="VIB71_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEQ8821824.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQC"
     gene            complement(61117..63282)
                     /locus_tag="VIB71_000060"
     CDS             complement(61117..63282)
                     /locus_tag="VIB71_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8821825.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQMTSDDTSSSNDISNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(63269..63877)
                     /gene="recU"
                     /locus_tag="VIB71_000061"
     CDS             complement(63269..63877)
                     /gene="recU"
                     /locus_tag="VIB71_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEQ8821826.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            63958..64473
                     /locus_tag="VIB71_000062"
     CDS             63958..64473
                     /locus_tag="VIB71_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEQ8821827.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQKVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            64595..64921
                     /gene="gpsB"
                     /locus_tag="VIB71_000063"
     CDS             64595..64921
                     /gene="gpsB"
                     /locus_tag="VIB71_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEQ8821828.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            64935..65303
                     /gene="rnpB"
                     /locus_tag="VIB71_000064"
     ncRNA           64935..65303
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VIB71_000064"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            65366..66520
                     /locus_tag="VIB71_000065"
     CDS             65366..66520
                     /locus_tag="VIB71_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEQ8821829.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWGNYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKVNGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            66534..68003
                     /locus_tag="VIB71_000066"
     CDS             66534..68003
                     /locus_tag="VIB71_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821830.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGYQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(68149..68631)
                     /locus_tag="VIB71_000067"
     CDS             complement(68149..68631)
                     /locus_tag="VIB71_000067"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEQ8821831.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(68705..70036)
                     /locus_tag="VIB71_000068"
                     /pseudo
     CDS             complement(68705..70036)
                     /locus_tag="VIB71_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
     gene            complement(70107..70865)
                     /locus_tag="VIB71_000069"
     CDS             complement(70107..70865)
                     /locus_tag="VIB71_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEQ8821832.1"
                     /translation="MHLSLVLQAELENNRFTFLKEGKTVVFSDINQEKLDQVVADYTK
                     EGYDAFSVVCDVTKEVAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFPTEKFEFM
                     IKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHGLIGLTKV
                     TALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPLVPQKRLI
                     DVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            complement(70917..71576)
                     /locus_tag="VIB71_000070"
     CDS             complement(70917..71576)
                     /locus_tag="VIB71_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8821833.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPSIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            complement(71578..72228)
                     /locus_tag="VIB71_000071"
     CDS             complement(71578..72228)
                     /locus_tag="VIB71_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8821834.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADIALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREVVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            complement(72252..73439)
                     /locus_tag="VIB71_000072"
     CDS             complement(72252..73439)
                     /locus_tag="VIB71_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8821835.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAARALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            73640..74536
                     /locus_tag="VIB71_000073"
     CDS             73640..74536
                     /locus_tag="VIB71_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8821836.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPL
                     ILSVVFSEVMSKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWKDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            74666..76273
                     /locus_tag="VIB71_000074"
     CDS             74666..76273
                     /locus_tag="VIB71_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEQ8821837.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            76383..77018
                     /gene="gmk"
                     /locus_tag="VIB71_000075"
     CDS             76383..77018
                     /gene="gmk"
                     /locus_tag="VIB71_000075"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEQ8821838.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            77034..77351
                     /locus_tag="VIB71_000076"
     CDS             77034..77351
                     /locus_tag="VIB71_000076"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEQ8821839.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            77416..79800
                     /locus_tag="VIB71_000077"
     CDS             77416..79800
                     /locus_tag="VIB71_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEQ8821840.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFVIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKAIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERQIDRSEPYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEARILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            79862..80797
                     /locus_tag="VIB71_000078"
     CDS             79862..80797
                     /locus_tag="VIB71_000078"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEQ8821841.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTLLLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            80787..82109
                     /gene="rsmB"
                     /locus_tag="VIB71_000079"
     CDS             80787..82109
                     /gene="rsmB"
                     /locus_tag="VIB71_000079"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEQ8821842.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLTYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSHRAVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            82147..82887
                     /locus_tag="VIB71_000080"
     CDS             82147..82887
                     /locus_tag="VIB71_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEQ8821843.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            82884..84782
                     /gene="pknB"
                     /locus_tag="VIB71_000081"
     CDS             82884..84782
                     /gene="pknB"
                     /locus_tag="VIB71_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEQ8821844.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIIFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEVTHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            84905..85597
                     /locus_tag="VIB71_000082"
     CDS             84905..85597
                     /locus_tag="VIB71_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEQ8821845.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDITVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            85594..86598
                     /locus_tag="VIB71_000083"
     CDS             85594..86598
                     /locus_tag="VIB71_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8821846.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLNMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            86591..87232
                     /locus_tag="VIB71_000084"
     CDS             86591..87232
                     /locus_tag="VIB71_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8821847.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            87269..88669
                     /locus_tag="VIB71_000085"
     CDS             87269..88669
                     /locus_tag="VIB71_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8821848.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPRLQEKADVITKKVEEDGILYALEELGLIDKELQFPQL
                     DLENHTGPKVTIKTNHGDMTLVLFPEHSPKTVANFLGLAKEGYYDGIIFHRVIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPTPIAAAYAENGGTPHLDRRHTVFGQLADDASFKVLDLIASVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            88669..89046
                     /locus_tag="VIB71_000086"
     CDS             88669..89046
                     /locus_tag="VIB71_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8821849.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALDNGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKASLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(89064..90005)
                     /gene="cysK"
                     /locus_tag="VIB71_000087"
     CDS             complement(89064..90005)
                     /gene="cysK"
                     /locus_tag="VIB71_000087"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEQ8821850.1"
                     /translation="MTKIYKTITELVGQTPIIKLNCLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKANPETAIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(90133..90765)
                     /locus_tag="VIB71_000088"
     CDS             complement(90133..90765)
                     /locus_tag="VIB71_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEQ8821851.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNSQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            90820..92145
                     /locus_tag="VIB71_000089"
     CDS             90820..92145
                     /locus_tag="VIB71_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8821852.1"
                     /translation="MESIENSYGRLLLENQLPDSARQLAQPLKSVVISRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSNKLLYAIPPMHFPKGNYLVWSGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            92117..92782
                     /locus_tag="VIB71_000090"
     CDS             92117..92782
                     /locus_tag="VIB71_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEQ8821853.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILDAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            92862..93410
                     /gene="raiA"
                     /locus_tag="VIB71_000091"
     CDS             92862..93410
                     /gene="raiA"
                     /locus_tag="VIB71_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEQ8821854.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
BASE COUNT        29227 a        16785 c        20023 g        28076 t
ORIGIN      
        1 aaggaggtaa tctatgctaa catacgacga atttaagcaa gcaatcgacc atgggtatat
       61 cacaggagac acagtagcga ttgtgcgcaa aaacggacag atctttgatt atgtgttgcc
      121 acatgagaaa gtaaagaatg gagaagttgt gacagatgaa aaagtggaag aagtgttgat
      181 ggaattggag taacattacc cgtcaatcac ccgtttattt ttattttttc atctttttct
      241 atcctttcta tattttaaaa ataccaacgt ttaagtgtct tgcaaaggat gaaaacggtg
      301 agatagctac cagcaatccc ctcctctcct tgtgagtaaa acaaagtgca tatccttgca
      361 ttcctcttaa attatggtat aataggctta aataatacag aaaggtggtg ggatatgtct
      421 cgccactttt gtattaagtg gactcccaag gaccaattat cttagagaag agcataaaaa
      481 tagaggaggt aatcaaaata gcaaatacat ctattatcga tatcgtaacc aagacagtaa
      541 cacctgagat taaggcacct tatgaattag tagacgttga atatgacaaa atgggtagtg
      601 actacatcct tagtatttta gtcgataagg aaggtggaat cacagtggaa gatacatctg
      661 acttgacgaa tattattagt ccgctgttag atacgattga tccagatcct tttccaaacc
      721 aatatatgct agaagtctct agtccaggtt tggagcgtcc gcttaagaca gctgacagtc
      781 taaaagcagc agttggctct tatatcaatg tgagtcttta tcaagctatt gataaggtga
      841 aagtttttca aggagactta ttagcctttg atggtgaaac gttgaccatt gattatcttg
      901 ataaaacacg tcataagatc gtgaatatac catatcaagc agttgctaag gtgagaatgg
      961 ctgtcaaatt ataactttta tttcaaagca ctaaactttt ttagaaacac ttaagcaaat
     1021 ttgaaacaac acctatagag tttatacaag ctaaacaaaa ggaattaagg gagcctttag
     1081 ggggctattg atcgtattaa tttaagaaag gatttttgcc aagctttaca agcaaggtag
     1141 ataacattat gagcaaagaa atgctagaag ccttccgtat tttggaagaa gaaaaacaca
     1201 ttgataaagc agatattatt gacgcagtga cagaatcatt aaagtctgcc tataaacgtc
     1261 gctatggtca atcagaatca tgtgttattg aatttaatga aaaaacggct gattttcaag
     1321 tattcacggt tcgtgaggtt gttgaagaag tttttgacag ccggcttgag attagtttga
     1381 aagatgctct tgctatcagt tctgcctatg aattgggtga taagattcgc tttgaagaat
     1441 ctgtcaatga atttggacgt gtcgcagctc aatcagctaa acagactatt atggaaaaga
     1501 tgcgccgcca aatgcgtgaa gtgatgttca atgaatacaa agagcatgaa ggtgaaatta
     1561 tgacaggaac agttgaacgg tttgatcaac gttttattta tgtcaatctt ggttccttag
     1621 aagcacaatt gtctcaccaa gaccagattc caggtgaaac tttcaaatca catgaccgta
     1681 ttgacgttta tgtctacaaa gttgaaaata atcctaaagg agttaacgtc tttgttagtc
     1741 gtagccatcc agaattcatc aaacgtatta tggagcaaga aattcctgaa gtctttgatg
     1801 gtactgttga aatcatgagt gtttctcgtg aagcaggtga ccgcaccaag gttgctgtgc
     1861 gcagtcataa tcctaacgtt gatgccatcg gaacaattgt tggacgtggt ggaagtaata
     1921 ttaaaaaggt catcagcaag ttccatccaa aacgtgtaga tgctaagacg gggcttgaaa
     1981 ttccagttga agaaaatatt gacgtgattc aatgggtaga tgatccagct gagttcatct
     2041 acaatgccat tgctccggct gaagtagaca tggtactttt tgacgatgaa gatcttaaac
     2101 gtgctacggt agtagttcct gatagcaaat tatcattagc tatcgggcgt cgcggccaaa
     2161 atgttcgttt agcggcacat ttgactggct accgtattga tatcaaatca gctagcgaat
     2221 atgatcgtct tgaggcggaa aaagaagcag caacagctgt ggaagagcca gttgttgacg
     2281 atgttatgac tgccgaggaa gtataagaaa agaggtgttt gatgtctaaa gtcaaaaaaa
     2341 tacctttacg aaaatcactt gtttctggtg aaattattgc taaacgagat cttcttagga
     2401 ttgtaaaaac taaggatggt caagttttca ttgatccaac tggtaaacaa aatggtcgtg
     2461 gtgcttatat caaattagac aatcaagagg ccttaatggc caagaaaaaa caagttttca
     2521 acaggagttt ctcaatggac attccagaaa gtttttacga tgacttgatt gcttatgttg
     2581 atcacaaaat caaaagaaga gagttaggtc ttgactaatt tagaaagatt atctagtctt
     2641 attggtctag ctcaacgggc tggaaaagtg atttcaggtg aagaactagt agtaaaagct
     2701 attcaacacc agcaggtaat attagtattt ttagccaatg atgctggtcc taatgtgaca
     2761 aaaaaagtga cagataaaag taattattat aatgtagaag tctccacagt gttgaatgca
     2821 ctggaattaa gtgctgcact aggtaaacca aggaaggttg ctgccattgc agatgctgga
     2881 ttttcaaaga aaatgaggac tcttatggaa tagatgaata ggaggacaca aattgtcaaa
     2941 gaaaagatta catgaaattg ccaaggaaat tggtaaaagt agtaaagagg tggttgaaca
     3001 cgctaaatac ttaggattag atgtgaaaag ccatgcatca agtgttgaag aagcggatgc
     3061 gaaaaagatt atttcaagtt tttcaaaggc ttctaaacct gatgtgacag cttctcaaac
     3121 agtcaaaccc aaagaagttg ctcaaccctc tgtaacagtg gtcaaagaaa caggttctga
     3181 gcatgtagag aaaacacagg tctctaagcc aaagagtcgt aattttaaag ctgaaagaga
     3241 ggctcgtgca aaggaacagg ctgctcgaaa acaagcaaat ggctcttctc atcgttctca
     3301 agaacgtcga ggaggttatc gccagcccaa taatcatcaa actaacgaac aaggagataa
     3361 gaggattact catcgttctc aaggtgatac aaacgataag cgtattgagc gaaaagcatc
     3421 gaatgtatca cctagacatg ataatcatca gctagttggt gatcgtaacc gttcctttgc
     3481 taaggagaat cacaagaatg gtcgattcac aaaccaaaaa aagcaaggac gacaagagcc
     3541 ccaatcgaaa agtcctaaaa ttgatttcaa agctcgtgct gctgccttaa aagctgaaca
     3601 aaatgctgaa tactcacgcc aaagtgaaac acgttttcgt gcacagcaag aagctaagcg
     3661 tttagctgag ttggcaagac aagaagctaa agaagcggct ctaaaagcac aagctgagga
     3721 gatgagccat cgtgaagcag cactgaaatc tattgaagaa gcagaaacta aattaaagtc
     3781 atcaaatatt agtgctaaat ctactgctga taatcgccgt aaaaaacaag cacgtcctga
     3841 aaagaatcgt gagttaactc atcattcaca agaaggacaa aagaaaaata agaagagttg
     3901 gaatagtcaa aaccaagtga gaaatcaaaa aaatagtaac tggaataaaa ataaaaagac
     3961 caaaaaaggc aaaaatgtta agaataccaa caccgctcca aaaccagtaa ccgagcgtaa
     4021 attccatgaa ttgccaaaag aatttgaata tactgaaggc atgacagttg ccgaaatcgc
     4081 aaaacgtatc aaacgcgaac ccgctgaaat tgttaaaaag ctgtttatga tgggtgttat
     4141 ggcaactcaa aaccagtctt tagatgggga tactatcgaa ttattgatgg tagattatgg
     4201 tattgaggct aaggctaagg tagaagtaga tgatgctgat atcgagcgct tctttgagga
     4261 tgaaaattac ctcaatcctg aaaatattgt agaacgcgca cctgttgtaa ctatcatggg
     4321 acacgtagac cacggtaaga caactttgct tgatactttg cgtaactcac gtgtggcaac
     4381 aggagaagct ggaggaatta ctcagcatat tggtgcttac cagattgaag aagctggcaa
     4441 gaaaattacc ttcttggata ctcccggaca cgcggccttt acaagcatgc gcgcacgtgg
     4501 agcttccgtt accgatatca ccattttgat tgttgcagct gatgatggtg ttatgccaca
     4561 aacgattgaa gcgatcaatc actcaaaagc tgctggtgtt ccaattattg ttgctatcaa
     4621 caaaattgat aaaccaggtg ctaatccaga acgtgttatc gcagaattgg cagaatatgg
     4681 tatcatctca actgcttggg gcggagagtg cgaatttgta gagatatctg ctaaatttaa
     4741 taaaaatatt gatgaactat tagaaacagt ccttttggtt gctgaagtgg aagaattgaa
     4801 agctgatccg acggttcgtg ctattggtac tgtaattgaa gcacgcttag ataaaggtaa
     4861 aggtgctatc gctacgcttc ttgtccaaca aggaactctt catgttcaag acccaatcgt
     4921 tgttggtaat acctttggtc gtgtccgtgc catggtaaat gaccttgggc gtcgtgttaa
     4981 atctgcggag ccatcaacac cagtttccat tactggtttg aacgaaacac caatggctgg
     5041 tgatcacttt gctgtttacg ctgatgaaaa agctgcgcgt gcagctggtg aggagcgatc
     5101 aaaacgtgcc ctcctcaaac aacgtcaaaa tacacagcgt gttagccttg ataatctctt
     5161 tgataccctt aaagcaggag aaatcaagac tgttaatgtc atcatcaaag cagacgttca
     5221 aggttctgtt gaagcccttg cagcatctct tgtaaagatt gaagtggaag gtgtccgtgt
     5281 caatgtcgtt cactctgctg taggtgctat caatgagtct gatgtgaccc ttgctgaagc
     5341 atcaaatgct gttattatcg gtttcaacgt tcgccctacc ccacaagctc gtcaacaagc
     5401 agatacggat gatgtggaaa ttcgtcttca tagtattatc tataaagtca ttgaagaagt
     5461 agaagaagcc atgaaaggga aacttgaccc tgtttaccaa gaaaaaattc ttggtgaagc
     5521 cattattcgt gaaaccttca aagtttctaa agtgggaaca attggtggct ttatggtaat
     5581 caacggtaag gtgacacgtg attcgagtgt tcgtgttatc cgtgatagtg tcgttatttt
     5641 tgatggtaaa ctggccagct tgaaacatta caaagatgac gttaaagaag tcggtaatgc
     5701 tcaagaaggt gggttgatga ttgaaaactt taacgatctt aaagttgacg atactattga
     5761 agcctatatt atggaagaaa ttgtgagaaa ataggggcta agaaggtctg agatgtaacg
     5821 tttttcctct gtcggaaata atgacttttt ctaccagatg agctacttag ggcattcctt
     5881 ccagtctcgt catggaattc tcagattccc tttaattgtc gttatcaaaa caggtagcaa
     5941 tgtcataagc tgagctttca gcctagcttt tgttttaaaa atgtggaaag gaaatggcta
     6001 tggctaatca tcgtattgac cgcgttggga tggaaatcaa gcgcgaagta aatgatattc
     6061 ttcagaaaaa agtgcgtgat ccacgcgttc agggagtaac gattacagaa gtgcaaatgc
     6121 agggtgactt gtcacttgct aaagtttatt acactattat gagtgacttg gcatctgata
     6181 atcaaaaagc acaaacaggg cttgaaaaag cgactggaac gattaaacgt gaacttggca
     6241 aacaattgac catgtacaaa attccagatt tggtgtttga aaaagacaac tccatcgcct
     6301 atggtaataa aattgatcaa ctcttacgag aacttgacaa caaatcctaa gtattgcggt
     6361 gcggatgtta tgacagaaag agccttatca ttatgatagg gctcttttta attgttattt
     6421 tgtggtgcaa actacaaaaa aaacaccaga ttaactggtg gcaggtagga attattcccc
     6481 tcattgagga gttttgttga tggcatcaat gatttggtat tgagctgttt ttgcctcttc
     6541 gataggataa attgggtaaa cgtggttcat gccttcttgg gtaatgaagg taatattgtg
     6601 gttagcggct ttcagttttg cggcataatc gcgaatatca ggataaaaga tctctcgtgt
     6661 cccagtaaat aaagtaattg gtggtagata agtgatcgga ccatttttag gactgacata
     6721 aatatggttg gtattatcag cagagtaggc ccacaattct cccactcgtt ttaatcccca
     6781 agaagataga ataggatcag catcttcgta gtttggaatc tctgggtgtg acatagtaac
     6841 atctaaccaa ggtgataaaa gaacgagctg ctttggttga gggactgatt cattgtgtag
     6901 ggcatgagct agacctaagg ctaaacctcc acctgctgaa tctcccataa ggaaaatatt
     6961 ctgattttta tggtaatagt gttggtaaag attgaccaat tttggcatag tatagttata
     7021 ggtataacgt ggggctttag gataaatggg taaaacaatt ttagcgtcaa gacttgtgga
     7081 taatgtcttt aacatattaa tatggtatgt cgttggattg ttaagataag aaccaccggc
     7141 aagataaata attgtttttt gatcaggttt tccattatca ttccaagagt aaacctgcat
     7201 gccataaaga ttttcttgaa caaggggacc attgactaaa ttagtatcta gttgataagg
     7261 tttatcagat tgttcacgac aggcatcaag gtatctttgg aagcttgggt catcttgttt
     7321 agaatagtaa ctcttgtcac gttttaacca gaaatattgc tcgataaacc agctcttcca
     7381 agaacgagaa ctagctgcaa ctggagtcgg caggcataag gtcagtaata gacctaaggt
     7441 gacaagtgtt tttcgaatag gatgtttcaa gggtatctcc ttaatgtaaa tgttattttt
     7501 attgcaataa tattatagta aaaacgattc atttgtcaat ataaggatag aaaaatgaga
     7561 aaagttattt atttacaaat gtagttaaat tcgttataat taatttacaa acgtaaatat
     7621 attgtgaatg aaggtgacgt tatgcaacag atatcagctg ccgaatggga agtcatgcgt
     7681 gtggtgtggg ccagtggtga tattaaaagt agcgatatta ttactatttt aaggaaaaaa
     7741 tatcaatggt cagattccac tattaagacc ctcattggta ggctagttaa aaaaaatctt
     7801 ttaacatctt atcgggaagg tagggcctat atttatcaag ctcttttgga tgagactttg
     7861 gtacaaaaag aagcactagc gactgtttta gacggtattt gtcagcggca acacacgcgt
     7921 ctacttcttg aacggcttta tgacttaccg atgaccttag aggaaattga ggcattccaa
     7981 gagctactag aagtcaaaaa agaaaatgca gttcttgagg tgccgtgtaa ttgcctgcct
     8041 gggcagtgcc actgtcagaa aaaggagacg tattaatggc taaagagata tttttagtgg
     8101 agggaatgag ttgtgcctct tgtgctctaa caattgaaaa aacggtcaat caattgcctg
     8161 aagtagaaca ggctgttgtg aatttagcga ccgagaaact cacggttact tatcaagatg
     8221 acgatttaga aacggccaaa gttattcaag cggtaaaagc tgctggttat ggtgcacaag
     8281 tctttgatga acatgcaaaa cacatgcaaa caggtcgtcg tgacgaagac ctaaaggtta
     8341 tttggtctca ggtcttgtgg tctgccctat tcaccattcc tatattatac ctagctatgg
     8401 gtcacatggt gggcttatgg cttccttcat ttctgcaacc agatcgctat cctttcgttt
     8461 atagctttag tcagctactc ttgacgattc cagtcttagt attaaatcgt cattattacc
     8521 ataatgggtt caaagctttg ttcaagggac atcctaatat ggactccttg gtagctttag
     8581 caaccagctt tgcttttgct tatagtcttt atggagtggt tgaaatcagt ttgggccagg
     8641 cgcactttgt gcactccctt tattttgaat cggtggtagt gattttgaca ctcatcggtc
     8701 taggaaagta ttttgaaagt cgttctaagg gccgtacttc tcaagctatt caaaagctcc
     8761 tatccttgaa ggctactgat gtgagggtat ggagaaacag ccaatggcaa ttgttaccat
     8821 tagaagaagt tagctatgat gaccttgtcc tggttcaacc aggtgaaaaa gtttctattg
     8881 acggtattat cgtggaagga catagcagtt tggatgaatc ctttttaact ggggaaagtt
     8941 tgcctgttga aaagggagaa aaagataatg tctttgcggg cagcttgaat gggccaggcg
     9001 ccctcacgat taaaccagat aagcttggga atgatacctt gttagcacaa attatccaac
     9061 tagttgagaa tgctcaagaa aataaagcac ctattgcagc tattgctgat agagtctcag
     9121 gtgtctttgt tccggtggtt ttggtattag ctctgttaac aggggtattt tggttggtat
     9181 tcatgcagga aagtcttcgt tttagtttga caacggccat cgctgttcta gtcattgctt
     9241 gtccttgtgc gcttggttta gcaactccga cagcgattat ggttggaaca gggcgtgcag
     9301 ctgaaaatgg tattcttttt aaaggtggtg acatcttaga acaagctcat caggtagata
     9361 cggttgtttt tgataaaacg gggacggtta cggaggggaa accaagtctt caaaagctcc
     9421 taattttttc gggagatgat caccttatct tgcaagaagc tgcttccttg gaggcctatt
     9481 ctcaacaccc cttaggggag gctattgttc gtgctgctca ggaagctggt tacgatagtc
     9541 taccagtgga acagtttgag tctttaaccg gcctaggagt cactggtcag cttgaagggc
     9601 gtcgtttggc gattggaaat gctactttaa tggcaattct tggtatcgat ttatcttgtg
     9661 ttcagtcagt ttgtgctaag gcttcaggaa aaggccaaac ccttgtatat tatgctaaag
     9721 aggggcagct acgagctctt ttcagtattg ctgacgctgt caaagaagat agtcaagcta
     9781 ccgtcgaagc tttgcagcaa ctggggattc acacgatcat gctaacaggt gaccacgatg
     9841 ctaccgctaa ggctattgcc tctcaagtgg ggattacaga tgtgattagt caagtcttac
     9901 ctgatcaaaa agcaggcgtg atagcagacc tccgctctca agggaaaaaa gttgctatgg
     9961 taggtgatgg tattaatgat gctccggcat tggccgtagc agacatcggg atagctatgg
    10021 ggtcggggac agatattgcg attgaatcgg cggatgtgat tctgatgagg tctgatatgc
    10081 tggatttggt gaaagtcatg tcattgagtc gagcgactat gaggattgtc aaggaaaatt
    10141 tattttgggc attcatatac aatgtcctca tgattccagt ggccatgggc ttacttcatc
    10201 tttttggagg cccattattg aacccgatgt tagcaggttt tgccatgagt tttagttcag
    10261 tatcagttgt tttgaatgca ttgcgtttaa aaggaaaaac catttaaagg agaatacaaa
    10321 atggaaaaac attatcaggt tacaggaatg acatgtgacg gttgcgtaag aacggtcact
    10381 gaaaaattat cagctgtccc cggtgtgcaa tcggtccagg taaatttgga aaaaggacag
    10441 gctaaggtga caggacgtcc tttaacgttc ctactcaagc gtgctttgaa ggataccaaa
    10501 tttgaattac atcaatcatc ttaggttatt ttggtagcct tacttcatct caaaagaggt
    10561 tccagtttaa actgggcctc ttttttatgg tcgctaataa agactctgac gttagcaggt
    10621 gtgttccgag caaaataaaa acacctctct ggaagcaaat cacttttgcc agaaggtgcc
    10681 gagggacgat gcgctgacag gctgtccatt cttgatgaaa cgtttactcc ttgttttcgt
    10741 gggctactaa taattgggtg aactgactat aacgttcaat gacttcctca gttatttgag
    10801 aatccgtaac aactgcatca atgttatcga gatggtagaa aacgaaaaag tcataggcat
    10861 tgaatttttg attgtctacc aagaggtatt tttcgataga gttgttgaag gctagttttt
    10921 gaatctctcc ttcagtttcg ctataagttg caatatcgtt tttataaatg ccattacagc
    10981 taataaaagc cttggcaaat tttaaggatg agatattttg actagcaagg gaccctacaa
    11041 aagctcctgt aatagatcgg tattcaccac cgataagaat caggtcaatg gtttcgctgt
    11101 cctgaaggat gttaaagaca gggaggctat tggtcacaat gcgaatctga cgatttttta
    11161 attgctcagc gaaacattct aaagttgttc ctggaccaat aaagattgtt tcaccatcat
    11221 tgactagttg tgtcgcatat gaagctagtt cccatttttc ctttgtttga acggtttgtt
    11281 tttcaatatt tgaccgctct tttttattag gcatggtaat actttgtgca cctccatgga
    11341 tgcggatcaa tttgccggct ttttccagtt catctaagtc tctacgaact gtcatatcag
    11401 aaacgtttaa agtctgaata atgtcattca cagtaacaat accttgctta ttgactattt
    11461 cggtaatttt tagaagtctt tctcttttta acatctaagg ggctcctttc tatagtttat
    11521 ttacttatgt ttatcatagc atatagacct tcatatttca ataaaacaaa ataaacaaaa
    11581 caaaaacaaa catatagaac aaaaaatatt gcgtaaaaat gttgaattat gttgaaggtt
    11641 atactataat gattttgtaa acggttacca atttgttgat gatgagatga cagttgttaa
    11701 aaattgatac ttatagaaag gcggtaggga gtgtttccta atattctatt tactgaagca
    11761 aggacgcagc cagagctttt tgatcttgtt gctagccact tggaaaaggt tgggtatgtg
    11821 acgcaagagt accatcaggc tttagtggag cgtgaggtgg tatttccgac aggactcaaa
    11881 gtggacctca aagatgggtc agatattttg tatgcggcta ttccgcatac agaaaccaag
    11941 tattgcttgg ttgatcaagt ggtctatgtt agaaatagtc aagcccttac ctttaagcac
    12001 atgattaatc cagaggaaga ttgtttggta acggatttct tctttattat caatagtcaa
    12061 aacgagggtc aaacgacgat tctatccaat ctcattacct tctttattac gaaaggcaat
    12121 ctgagctatt tagccagtct aaaagatgat aaacaagcta tttcaaacta tttaatagaa
    12181 aaaggagtgt ttcagcatga ttaaaattct agcagcctgc ggtgcaggtg ttaactcaag
    12241 ccatcaaatt aaagatgcta tcgaaagcca aatgactgat cgtggctatg atgtgcattg
    12301 tgatgcggtg atggtcaaag acatcacaga agaattggtg tctcgttatg atatttttac
    12361 gccgattgca aaaactgact tgggatttga cctgccgatt cccatagtag aagcaggacc
    12421 gattctctat cgtatcccaa tcatgagtga gcctgttttt gctgaattag agcgcgtgat
    12481 taaagaaaac catttgcagt gagttaataa aaacataagg agacaagatg atgcaacctt
    12541 ttttagacat tattaacaag attctgggat ttcctattca gttgggatca ggtgtggtca
    12601 tgctgattgt catgacaggt ttagccatga ttttcggggt taaattcaca aaggcactgg
    12661 aaggcgggat taagttagct atcgctctta caggtattgg agccattatt gggattttga
    12721 cgggggcttt ttcagagtct ttacaggcct ttgttaaaaa tacagggatc agtttaaaca
    12781 ttattgatgt cggttgggca ccgcttgcaa caattacctg gggttcccct tacacccttt
    12841 atttcttgct ggtgatgctg gtggttaata ttgtcatgat tgtcatgaaa aaaacggaca
    12901 cccttgacgt cgatattttt gatatttggc atttatctat cacaggtcta ttgattatgt
    12961 ggtatgcggc tcgcaaccat ttaccagtct ttgtgtctct tttgattgct actgtggcag
    13021 ttattcttgt tggggtattg aaaatcatta actctgattt gatgaaaccg acctttgatg
    13081 accttcttgg gacagggtct caatcaccaa tgacttcaac tcacatgaac tacatgatga
    13141 atccaatcat tatggtctta gataagattt ttgacaaggt ctttccgggg ctagataaat
    13201 atgactttga tgctgctaaa ttgaacaaaa aaattggctt ctggggctct aagttcttta
    13261 tcggaatggc tctaggtttt gtgattggga ttatgggaga tcctcatttc actgttgaat
    13321 ctatcaaaaa ttggtttggt ctaggcttta ccgcgggtgc ctgtttggaa cttttctctt
    13381 tgattggttc ttggtttatc gcagctgttg agcctttgtc acaagggatt actaattttg
    13441 ccaatgctag aatgcatgga cgtcgtttca atatcggttt ggactggcct ttcattgctg
    13501 gtcgcgctga aatctgggcc tgtgccaata ttcttgcccc aatcatgttg attgaagctg
    13561 ttcttctttc aaaagttggc aatgggattt taccattggc gggaattatt gctatgggga
    13621 tgacaccagc tcttcttgtg gtcacacgtg gccgtttgat tcgcatgatt atttttggct
    13681 ccctcttatt gccgttattc ctcttgtcag gaaccatgat tgccccattc gcaactgaat
    13741 tggctaaaaa agtaggcgct ttcccagcag gtgcaagtgc tggttccttg attacgcatt
    13801 cgactctcga aggaccaatg gaaaaaatct ttggttatgt gattggtcaa gcgacaacag
    13861 gtcagattgc ctcaatcatt acgttaatca tctttgtggc catttaccta ggtctctttg
    13921 cttggtatgc taaccaaatg aaggcacgta acgctgagta tgcgaaaaca atgacataaa
    13981 atcaggttag gtgactaact aaaaaactat tgggaatagc agataaccgc ttaaggtatt
    14041 cctgctttat ccccctagag agaaaagagt attcctcatg taaggcaagg cgctctgtgg
    14101 gtacccgcaa gcgcttttct tgaaagaaat aatggaagac aactaagact gctggcaata
    14161 atcctgacct aaggacaggt aatcctgtta cctttttgta gattggtaag cagtttggat
    14221 tagaaaagga gaaacgatgg ctattatttt aggtgcagat gcacacggaa atgcattaaa
    14281 agaattaatc aaaagttttc ttcaagaaga aagctatgac attattgacg tgactgatat
    14341 taacagtgat tttattgata acacattagc ggtggctaaa gccgttaatg aagcagaagg
    14401 tcgtttaggc attatggtgg atgcttacgg agcaggtccc tttatggtag ccacaaaact
    14461 aaaaggaatg gttgctgctg aagtttcaga tgaacgctct gcttacatga ctcgcggtca
    14521 caacaatgcc cgtatgatta ccatgggagc agaaattgta ggtccagaat tagcgaagaa
    14581 tatcgccaaa ggttttgtga ctggccacta cgatggtggt cgtcatcaaa ttcgtgttga
    14641 catgctcaat aaaatggctt aaaggaggat aaagagatga aaattgcgat tggatgtgac
    14701 catattgtca ccaacgaaaa aatggctgtt tctgattttt tgaaatctaa aggctatgac
    14761 gttattgact gtggcactgg agttggcatt aacaatgcgg taaataaggt accaggtatt
    14821 cgttcagccc ttgttcgaga tatgacaaca gcgctttatg ccaaggaaga attgaatgcc
    14881 aatgtgattg gctttggtgg taaaatcacg ggtgaacttc ttatgtgtga tattatagat
    14941 gcttttatca aggcagaata caaagaaact gaagagaata agaagctaat tgctaaaata
    15001 gcccacttgg aaactcatca tgccagccaa gaagatcctg atttctttac agaattctta
    15061 gaaagatggg atcgtggcga gtatcacgat taggaagaag agatgagttt aacagttatc
    15121 ttaaatcctt ctgtcgctat ttcctatcct ttagattgtc tggctatgga cacgggacag
    15181 aacggcaaaa acagctggcg ataaggagct aaatgtgacc agaatgttag caaaagctgg
    15241 tcagttatgg caataggatt tagtggtggt aaactgggtg actttatcat tcatcagtta
    15301 caagaacagg gcatttctaa ccaatttttc aaaatcaaag gggaaacgag aaattgtatt
    15361 gctgttttac atgaaggcat gcagacaaaa attttggaag ctggtcccta cagtgatgtg
    15421 gacgaagccg aagtctcttt gagccacatg agtactattg ctaagccgtt tgatgtctta
    15481 atttctcagg cagtctgcct aagagactag ctactcacta ttatcaagat ttgatgacta
    15541 tggcaacttt taaacaatta tatcagcaac ttcaagtaag agaggtatca catgacaatc
    15601 acagcaaata aaagacatta cttagaaaaa gtgagccatc aaggaatcat atcagcttta
    15661 gcttttgatc aacgaggtgc actgaagcaa atgatggcag cacatcaaga aggagaagcg
    15721 acagttacac agatagaaac attgaaagtt ctcgtttctg aggaattgac gccttatgct
    15781 tcatctattt tattagatcc agaatatggg ttgctggcta ctaaggtaag agctaatcag
    15841 acaggcttac tgttagctta cgaaaaaaca ggttatgatg ctacaaccac tagccgttta
    15901 cccgattgct tagtggaatg gtcggtcaaa cggttgaaag cagcaggtgc agatgctatt
    15961 aaatttttgc tctattatga tgttgatgga gatgaacaaa tcaatttaca aaaacaagct
    16021 tatattgaac gcattggttc agaatgtaca gctgaagaca tccctttttt tcttgaactt
    16081 ttgagttatg atgagagaat atcagataac aacagtgcgg catacgcaaa gcttaagcca
    16141 cataaggtta acggtgctat gtcagtattt tcggataagc gttttggcgt tgatgtgcta
    16201 aaagtagagg ttcctgttaa tatggcttat gtagaaggtt ttactgaagg ggaagtccat
    16261 tacagtcaag ctgaggctat taaagctttt caagaccaag aagctgccag ccacctccct
    16321 tatatctatt tgagtgcagg cgtatctgcc aaactttttc aagagacatt atactttgca
    16381 gcagcagcag gtgctcaatt tagcggtgtt ttgtgtgggc gtgccacgtg ggcaggatcc
    16441 gttccagttt atattactaa aggagaggac gaagcaagaa agtggctatg cactgaaggc
    16501 ttccaaaata ttgacgagtt aaacagggta ctcgaagaga cagctagccc ttggacggaa
    16561 aaaatctaaa acaaccttat cctatcaagc agctctcatt gatgtgataa gataagtatg
    16621 gggataattg tgtgaatctt ttgtagcaag gatgaaaatg ggttttatcc ttgctttttt
    16681 atccttacat tttatctttt tctacttatt ttttaaagga aaacgtggta aactaaaaga
    16741 agactaaaag acaatagggt agcttatgac aattgatatg tgggaaattt taaatatcat
    16801 cgggaccatt gcctttgctc tttctggtgc tattgttgcc atggaagaag aatttgatat
    16861 tttagggatt tttattttag gtttcgtgac agcctttgga ggcggagcca ttcgaaacac
    16921 cctaattggt ttacctatag aggccttatg ggggcaaaag ccagaattca cttgcgcttt
    16981 ctttgctatg gttttgatta tgctttttcc taagctaata gctagaggtt gggtacgggc
    17041 agctgttttg actgatgcca ttggtctggc agcttttagt gtccaaggag ccttgcatgc
    17101 tgtccgtctt aaccagcctt taagtgctgt cattgtagca gctgtgttga ctggtgcagg
    17161 cggtggtgtt gtcagagata ttctggcagg gcgaaaacct agtgttttgc gtagtgaaat
    17221 ctatgctggg tggtctattc ttgcagctat tgttttgcat tttaaactag cagattcaac
    17281 gattgaatgt tatgccttgg ttgttttact cacgacttta cgcatgattg gcaaccgtaa
    17341 aaaatggaac ctccctaaaa tcaaatggaa agaggaaaga taggatgatt caactaattg
    17401 caattgattt ggacggcacc ttattaaacc aggacaaaca gattccaaaa gagaatatca
    17461 cagccatcca agaagcagct cagtcaggct taaaaattgt cttatgtaca ggccggcctc
    17521 agtcagggac aagaccctat tttgaccaat taggtttgac acaagaggaa ttcctcatta
    17581 tcaataatgg ctgtagtact tatagtagtc ctgactggca attacgccat tcaaaaatgt
    17641 tgaaggtttc agatattgaa ttgctggaag agctaagcca aagttttcca gatatttacc
    17701 tgactttaac tgaggaaaac gattatttgg tgcttgaaga agaagtgcca gaccttgtgc
    17761 aggaagatgg agatttggta tttaccattg tcaagcctgt ctccttagca gagctgtcgg
    17821 acactcctcg cctgattttt caagccatgt acttaggaga aaaagctgcg ctagatgcct
    17881 ttgaacgtgc ggtgagaaat cagcttagtc agagtttcca tgttgttcgt agccaagata
    17941 atattttaga aattctccct cagggagtca gcaaggcatc ggctctcaaa gaattagtag
    18001 aagatttggg tttaactgct gaccaagtga tggctattgg ggatgctccc aatgacattg
    18061 agatgttaac ttatgctggt ttaggagttg ctatggaaaa tgcttcagca gctatcaagc
    18121 cattagctga caaagtcact ttgactaatg atatggcggg tgtggcccag gctatccgtc
    18181 agtttgcact tgcagctcaa aaagactaac tattaacgta aaaaggttcc caaaaggaac
    18241 ctttttacgt taatagaggc aagcccatag cagccatttc ttcggcagga acgatcatgt
    18301 catctgaaat ccagtttgtc aagacagaaa caatagcatt gctccaaaaa aggcgcttat
    18361 agtgcgattg ttttttgtct tttaattttt gataagcttt cagacgttta gtgactaatc
    18421 gtgttagaag atggtgcagg tgatgtttga aaatcatttt aagaagctga gcttcttttt
    18481 tagcttcagt aaaaagatag agccaggctt gataagcctg agttttaata tcaaattgtt
    18541 ttagtccacg aaaaatacga cggataacac ctactaacag ttgttctata atggcttctt
    18601 tagaggtata attacgataa aaagcgttac gagatactcc tgctttcgtc accaattctg
    18661 aaatcgtaat atcacctaaa ggttttattt ctagaagatt tagtaaggcg atttccatag
    18721 attcacgtgc tatgcgtcgt gtttctttat taaattgtgt taagttttga agtgatcttt
    18781 ttgagagtgc tttatcagtc atcacaaata cctttcaagt gttacatctg atgagttatc
    18841 agtagcaaaa accgacttaa taatgatata attttatggg aaaagtctta gtttgtcaac
    18901 taaagttagt tatcaggagc ctcattacct ccttgtatag ctctattgga tgactttact
    18961 aactattgaa aaggctagta ataaaacata ggatttaatg actagttatt accattagcc
    19021 tagacatctt agcgaaggct taataatctg gtctttgtta ccgaacacaa attagagaaa
    19081 aagaaggata aaaaatgact tggaaaattg taacagattc aggatgtgat cttagaagtt
    19141 tgactagaca atccaaagag ttgcgctttg aacgtgtgcc tttgacccta cagattggca
    19201 cagaaatttt tagagatgat gatggattag atatcgataa tatgatgaca actatgtacc
    19261 agtcgtctaa agcaacgaca tccagctgtc caagcccaga agcctttttg caggcctata
    19321 gaggtgcaga taatgttatc gtgatgacaa ttacagggac cttatctggc agtcataata
    19381 gtgcacgact ggctaaaaat gaacttcttg aagaaaatcc taatgtcaat attcacctaa
    19441 tcgattcttt atcagcaggt ggcgagatgg atttgctcgt actggagctt gagcggttga
    19501 tcaatcttgg attatccttt gaagaagttg tcaaacagat cacagcttat cagcaaaaaa
    19561 cacgtttgat ttttgtgctt gccaaggttg ataatttggt taaaaatggt cgactgagta
    19621 aattagtagg taaagtaatt ggcttactca atattagaat ggttgggaaa gctagcaata
    19681 aaggaacgct tgaacttctt caaaaagcgc gtggtcaaaa aaaagcagtt tctgctttga
    19741 tagaagaaat tcaaaaagag ggttatgtag gcggaaaagt ttacattgct catgctcaaa
    19801 atccaaaaat ttgtgagcag atcagtgaaa aaattaaatc tttatatcct gatgctgtga
    19861 ttcaaactgg aaggacctca ggtttgtgta gcttttatgc tgaagacgga ggacttttaa
    19921 tgggctacga aatttaatgc tatctaacaa aacaaaaagc tagactcttt tgatttgagc
    19981 tagctttttt aagatatcag gaagactaat cactaagata gccgtctaaa acgtttattg
    20041 attgatttta cgaaaaattt ttgtattact cttttgatga ttgcttgtct cctgagtcgg
    20101 aaggttctga agaggtctga ggtggaattg gatcaggatg actaggttgt ggcgtaacat
    20161 ctgaagctga agattctgag cttgggtcta aagtaggtga ctgggaatta tcataagtat
    20221 ctgagacgtc tcctgggaaa ggtgtccagt aagagttatc tgttatttct ccactttgtc
    20281 ttggaaattc atcaataata ggtttcgctg gtaaaatagc gtctaaccga gattgtaaag
    20341 cggctttttt acctttgtta cttaagtcgt taactgcttt ttgggcgata tctttaagat
    20401 tttgattgag agtctcctca gcagctttaa ctgcttgagt agctgcatct tcttgctctt
    20461 gctttgcttt ggcaacgttt agctgttctt gtagcgtttt tttcttagaa gattctgcta
    20521 atttatcaac agctttctgg gcttcttgga tagcagctgc agtggctaaa cgatcagcgt
    20581 cattaactgc tttaactgct ttttttagta aactagcagc acttttagaa tgtttagcta
    20641 ccttatcttg cgtttgaggg taggatccaa aaataaggca ggagccacct attagagtga
    20701 tagttagaac actcaacatc caataaagcg cctctttttg tgatttagtc atggaatctc
    20761 ctttatgata ttgtttcatc gtagccatat tatacctcta attaaacgaa atgaaaagat
    20821 ttgtgcaaaa acaaatgatg taaaatatcg gaaaagccta acaccttatc aaaccaataa
    20881 tatgcaaatg ttgacatcgg tatacacaga aacgcttaaa aaaaccttgt gataaagacc
    20941 gtaatacatt aaaatagaat agactaaaaa attgagcgag gacaatattg tgtcagtaaa
    21001 ttggcaagac attgcatttc atttctttgg aggcttaggt ctctttcttt tcagtatcaa
    21061 gtatatggga gatggtctgc aacaagcagc aggagataaa ctaaggtatt acattgataa
    21121 atacaccagt aatccctttt ttggtatctt agtcggaatt gccatgtctg ccttaattca
    21181 gtccagttca ggcgtaactg tgattacggt tggtttggtt tctgcgggtt tgctaaattt
    21241 gcgacaagcc attggaattg ttatgggggc taatattgga acgactatca cttcgttttt
    21301 aattggtttt aaactaggag attacgcctt gcccatgatt tttattggtg cagcctgtct
    21361 tttctttacc tctaataaaa agctcaacaa ttttgggcgt atcatttttg gtgtcggagg
    21421 aattttcttc tcgctgaacc taatgggaga tgccatggat cctttgaaat ctgtgtcagc
    21481 ctttcaaaat tatttagcga cattaggtga taaacccttc caaggtgtct ttatcggaac
    21541 ggctttgacc atgttgattc agtcatcggc agccattatc gggattttac agggtctgtt
    21601 ttcaggcggt cttttgacct tacagggggc tattcctatt ttgttaggct caaatatagg
    21661 aacctgcatt acagctgtct tagcagctat aggttcaaat attgctgcta aacgtgtggc
    21721 agcagctcat gtgttattta atttgatcgg tacaattatt tttatgatta tcctagtccc
    21781 attcacatca ttgatgttat ggctacaatc aaagttgagt ttaacacctg agatgactat
    21841 cgctttttct cacggctctt ttaatattac taataccatc ttattaattc ctttcattag
    21901 tctactagct atgattgtga ctagactcat tccaggagaa gatgaagtgg tcaaatacga
    21961 agccctttat ttagatcgct tacttattac ccaagcccct tctatcgcac taggaaatgc
    22021 ccacaaggaa ttggttcatt tagcctctta tgcgattcaa gcttttgaag cttcttacag
    22081 ttatattatg acagctgacg ataaatttgg ggaaaaggtc aagcgttatg aaagagcagt
    22141 tgataccatc gatgaggagt taaccactta tttggttgat atttctaacg aagccctcag
    22201 cccaagtgaa aatgaagtct tggctggtat tcttgactct tcacgtgatt tggaaagaat
    22261 tggagatcat tctgagtctt taggcattct aattgaaggc atcatatcta aacaaattgg
    22321 tttttcaata tctgctcgtc aagaattgac agagatgtat caattgacgc attgtttaac
    22381 actggatgcc attagagcta tcgttgatag tgatacagac ttggcgcaaa ctattgtgac
    22441 tcgccataaa gaaattgaag aaaaagagcg acgattacgt aaaacccaca ttaagcgctt
    22501 gaattgtgga gaatgtacgg cacaagcagg tattaatttt attgatatta tttcccacta
    22561 tacccgcatc acagatcatg ccttgaattt agcagagaaa gtactttcac accagcttta
    22621 aaaaaagaga aaacgtgaat gatcatccac gttttctttt ttgaatccaa aaagtggtat
    22681 ataccattta caaagtaaag aataagtcgt ataatagggg aaaaagggag gaaaaaagat
    22741 gacatgctat cttaaagcag attgttttta ttacccaaca gaggtcaaac cggctggcta
    22801 cctaagtctt catgatggtg tttttgggga gtggacagaa attgttccgg cagatgcgca
    22861 aatcattgac tacaccggtt atcaaattgc accaggtctt gtggatacgc atatccatgg
    22921 ctatgcggga gctgatgtca tggataattc tgcccaaggg attcatcaaa tgagtgaagg
    22981 actattagca acaggagtaa cgtctttttt accgacgacc ttaacttcta cctttgagca
    23041 gttagaaaaa gtatcaggga ctattgcttc agttgctgat caggtaaaag gtgctaaaat
    23101 acaaggtatt tactttgaag gtccttattt taccgaaaaa tataagggtg ctcaaaaccc
    23161 aagttatatg aaaaccccac gcttggagga atttgatgct tggcaaaaag ccgctaaagg
    23221 gctcatcaaa aaaattgccc ttgctcctga gcgtgatggt gtcaaagaat ttgtgtccgc
    23281 agtgacaaaa caaggcgtaa cagtggcctt agggcattca aacggtactt atcaagaggc
    23341 taaagaagct gttcaagctg gtgctagtgt ttgggttcat gcttataatg gcatgcgagg
    23401 attgacccac cgtgaaccag gaatggtggg agcggtttat aatcttccaa atacttacgc
    23461 agagttgatt tgtgatggcc accatgtctc accaattgct tgtgatattt tgatgcagca
    23521 aaaagggcat gatcatgtag ccatgattac ggactgtatg cgagcaggtg gttcaccaga
    23581 tggtgattac ctcttggggg aattctctgt ggttgtggca aatggcactg ctcgtcttaa
    23641 agagagtgga aacttggcag gatctatttt gaaattaaaa gacggcctta gaaatgtagt
    23701 ggcctgggga atcgcaactc cggcagaagc cattcatatg gcaacctatg tgccagctgt
    23761 ttctgtcggt attgacgacg tatgtggtca aatcaaagct gggcatgcgg ctgactttat
    23821 tgttcttgat aaggatttaa cacttgttgc aacctattta aatgggcaaa aagcttttga
    23881 tgcctaagag atacaaaagg attggggtag ctatgtctgg caggccaatt ctttttgtat
    23941 tttctttctt tatgatagaa tagattacag taatcgctta cagagattga taaaaggagg
    24001 tttttgtgat ggtaacaaca gtaaaaatga caagtggcta tgagattccc gttttaggat
    24061 ttggaactta ccaagcagcc gatggtgagg aagcttacca atctacctta gcagccatca
    24121 aggctggcta tcgtcatatt gacactgcag ctatttataa aaatgaagaa agtgtgggtc
    24181 gtgccatcaa ggattctggg gttctacgag aagacttatt tattacaact aaactctgga
    24241 atgacgccca tagttatgaa ggggcaaaag acgctttagc tgcttctctt gaccgtcttg
    24301 gtctggatta tgtggatctc tatcttatcc attggccaaa cccaaaagct ctgcgtaaca
    24361 cttggaaaga ggcaaatgct caagcatggc aatatatgga agaggcggtt gaagcagggc
    24421 tcattaaaag cattggcgtc agcaatttta tggtgcatca tctagaagct cttcaagaga
    24481 cagctaaaat aactccagca attaatcaga tccgattagc cccaggttgc tatcaaaagg
    24541 aagtggttga ttattgtaag gcaaatgaga ttttattgga agcttggagt cctctaggac
    24601 aaggggagat ttttgataat gagactatgc agcagttagc taataaatat gacaaaacag
    24661 tggcacaagc tgccttagct tggtcgctgg cagaaggttt tattcccttg ccaaaatcgg
    24721 tgcatgatga gcgcatcaag gaaaatatgg ctatttttga tgtgagcttg acaccagaag
    24781 ataaaaaaac aattcgctat ctctcaggaa tgtcagcgat tcctaaccct gatactacaa
    24841 gtttttaaga aactacaaag atttagccat aattcgctaa atcttttttg aaaacggttt
    24901 gacaaaggtt tatcatttag ctataatctt tattagtgtt ttgtgaaaga aactattatt
    24961 gaaaataagg agccgtattg tgaccatctt tttagtgatg ttagccatgt ttactattcg
    25021 tttagtattt ttgaagaaat cgataacaaa tgaaaaagcc atattagccc aaggaggaca
    25081 ggaatttggt gctcagaaca cgaaattttt gacgttactt cacattatga tttatgtgtt
    25141 tgcggtgatt gaagcgctgc ttaaacaaat taagtttgat ggcatcagtt ttttaggtct
    25201 tttgttgatg ttattatcag tagctgtttt atatgaagtg acacgtatct taggtgacat
    25261 ttggactgta aaattgatgt tagcaaaaga ccacaaatat gtggatcact ggttgttcaa
    25321 aacgattaaa catcctaact actttttaaa tatcgcccct gagctggtgg gcatagcctt
    25381 actttgccat gctaaaatta cggctatgct tcttttccca tgctacattg tagtaatata
    25441 tttacgtatt cgagaagaaa ataagctatt agcggaagtg attattccaa acggtactcg
    25501 aacaaaacct taagctcatg atggacaaac taatggcttt atgctaaact agactctagg
    25561 aaaaaggatg caagtatctt atctaaagcg agttcggggt agttagagcc gaatggtagg
    25621 actgcagatt ggcgcttccg tttgggcagt gtgattaagt atatttgtca atattgccca
    25681 aaaagatact atataaatga agtaataaat tagggtggaa ccgcgttttg acgcccctag
    25741 gtcttatgat ttaggagcat caaaatgcgg ttttttggtg cctagacctg taatacatgc
    25801 tagtaacatc gtcaggtatt ttactgatga caaaaaaacg attgtcaatg atataccatt
    25861 ttactactat caaaggagta cgaaatgtct aaaaaactta cctttcaaga aatcatcttg
    25921 accttacaac aatattggaa tgatcagggt tgtatgctca tgcaagccta tgacaatgaa
    25981 aaaggagctg ggaccatgag tccttacacg ttcttacgtg ctataggtcc tgagccatgg
    26041 aatgcggctt atgtagagcc atcacgtcgt cctgcagatg gccgttacgg agaaaaccca
    26101 aatcgtcttt accaacacca ccaatttcaa gtggtcatga aaccatcacc atcaaatatt
    26161 caagaacttt accttgcttc tttggaaaaa ttgggcatca atcctttaga acatgatatt
    26221 cgttttgttg aagataactg ggaaaaccca tcaacaggat cagcagggct tggttgggaa
    26281 gtttggcttg atggaatgga aatcacacaa tttacgtatt tccaacaagt tggtggcctt
    26341 gcgacatctc cagtgacagc agaagtaact tatggtcttg agcgcttagc ttcctatatt
    26401 caagaagtgg attcggtcta tgatattgag tgggcaccag gtgttaaata tggtgaaatc
    26461 ttcttacaac ctgagtatga gcattcaaaa tattccttcg aaatatcaga ccaagacatg
    26521 ctgcttgaaa actttgaaaa gtttgaaaaa gaagcctcgc gtgccctaga agaaggtttg
    26581 gttcacccag cttatgatta cgtgctcaaa tgttctcata cgtttaacct gctggatgcc
    26641 cgtggcgctg tttccgtcac agaacgcgca ggctacattg ctcgtatccg taatttggca
    26701 cgtgtcgttg ctaagacctt tgttgcagaa cgcaagaagc ttggattgcc actgttggat
    26761 gaagcaacac gcgcaatctt gctagctgaa gatgacgaat aagtcgattt aaagatgatc
    26821 tagttgcgag ctttgtaatc ttaagagcga gcaagaagtg ggcgaccgaa ggtcgccgag
    26881 tcaaggttac tcccgctgta gtgacaattc ggtaaggtta cttatcgaac gagggagttg
    26941 gcgagacttt aggctggcta actaggaatg gaacactttt gttttctgaa attatccact
    27001 ggataatttc actttgcgtc ccccctacct aagggaacaa tcaaaaagat actttttaga
    27061 gaaaggaact gaacatgggc tacggactat gtcaaaaaga ccaagacttc ctaggtgcaa
    27121 gcacctgcgt cgctttgcta ttttgatggt gtccgcttaa cgcccttggt atcttaatta
    27181 tgagtaaaaa tctactaatc gaacttggtc tggaagaact tccagcctac gtggtcacac
    27241 caagtgaaaa acaactggga gagcgcttgg cgactttctt aacagaaaat cgtctctctt
    27301 ttgaagatat acaaaccttt tcaactccac gccgtttggc agtgcgtgtg tctggattag
    27361 ctgatcagca aacggatttg actgaggact ttaaagggcc tgctaagaaa attgcccttg
    27421 atgctgatgg gaatttctca aaagctgctc aaggatttgt tcgtggcaaa ggcttgacca
    27481 cagatgctat cgaattccgc gaagtcaaag gagaagaata cgtttatgtg accaaacacg
    27541 aagctggaaa acctgctaag gaagtgcttc taggcgttac tgaagtgttg tcagcaatga
    27601 ccttcccagt cagcatgcac tgggctaaca atagttttga atatattcgt cctgttcaca
    27661 ccttgacagt tctgttgaat gatgaggcct tggaacttga cttcttggat attcattctg
    27721 gacgcgtcag ccgtggtcac cgttttttag gtactgaaac cactatcaca agtgctgatt
    27781 cttatgaggc tgatttgcgc agccaatgcg tcattgttga cgctaaagag cgtcaagaga
    27841 tgattgtgga gcaaatcaag acgcttgaag tggagcaggg tgtgcaagtt gacattgacg
    27901 aagacttgct taatgaagtt ttgaacttgg tcgagtttcc aacagctttc atgggaaatt
    27961 ttgaggctaa ataccttgat gtcccagaag aagtattggt aacatcaatg aaaaaccacc
    28021 aacgttattt tgtggtacgt gatcaggctg gtcacttgat gccaaacttt gtatcagttc
    28081 gtaatgggaa tgatcaagcc attgaaaatg ttattaaagg gaacgaaaaa gttttggtag
    28141 ctcgcttaga agatggtgaa ttcttctggc gtgaggatca gaaattgcaa attgctgatt
    28201 tagttgccaa attgaccaat gtgaccttcc atgaaaaaat cggctctctt gctgaacaca
    28261 tggatcgtac gcgtgtcatt gccgcatcac ttgctaagga agccaaccta tctgctgagg
    28321 aagtcacagc tgttgaccgt gctgcccaaa tttacaaatt tgacctttta acaggtatgg
    28381 ttggtgaatt tgatgagctg caagggatta tgggtgaaaa atatgctctt ctagctggtg
    28441 aagatgctgc tgtggcaaca gcaatccgtg aacactactt acctgatgct gcaggaggtg
    28501 cgctacctga aaccaaagtt ggcgttgtcc tggccttggc agataaattg gatactctct
    28561 tgtcattctt ttctgttgga ttgattccat ctggctctaa tgatccttat gctctacgtc
    28621 gtgcaacgca gggtatcgtt cgtattcttg atcattttgg atggcgcatc ccaatggata
    28681 agctggtaga tagcttatat gacttgtcct ttgatagttt gacctatacc aataaggcgg
    28741 atgtgatgaa ctttatccgt gctcgtgtgg ataagatgat gggcaaagcc gcaccaaaag
    28801 acattcggga agctattcta gcaagttcaa cctttgtggt tccagaaatg ttagcggtag
    28861 ctgaagctct tgtcaaagcc agccatacgg aaaattacaa accagcagtt gaatctttgt
    28921 cacgtgcttt taatttggca gaaaaagcgg acgcttctgt tcaggtggac cctagcctct
    28981 ttgaaaatga gcaagaaaac actttgtttg cagctattca aggcttaact ctagcaggca
    29041 gtgctgccca gcagttagaa caggtctttg cccttagccc agtgattaat gatttctttg
    29101 ataatacaat ggttatggca gaagatcaag cccttaagaa caaccgtgta gctattttat
    29161 cagatttagt aagcaaagct aagaccattg ctgcttttaa ccaactaaac accaagtaaa
    29221 tagaaaggaa agagccgttg gggacttagc tagaaaagtg agttcagtac ccgagtggaa
    29281 agaacaaggc ctttaaacat tgcttttcac agtgagagtc aagtcagttt tttaagtctt
    29341 acactttttt cccaggctct tagtggctta acatggatcc taaaaaaatt gctcgtatca
    29401 atgagctggc taaaaagaaa aaaacggtag gcttgactgg acctgaaaaa gtggaacagg
    29461 caaaactccg tgaagaatac attgaaggct atcgtcgctc tgtcagacac catatcgaag
    29521 gcatcaaatt ggtggacgaa gaaggaaacg acgtgacccc tgaaaaatta agacaggtgc
    29581 aacgtgaaaa aggcttgcac ggccgttcat tagatgaccc aaaatcataa gacaaaaagc
    29641 agctctgaac tgctttttgt ttatcgtgat gactgttagc ttttatttta aatggtatga
    29701 tacttcaaag tgaccacacg tttttatatt gtatagtcaa aatattggga aaaaccatgt
    29761 gtttgagtta taatagaaga aatcaaagaa agaaggtagt acttatgaca attaaaaaat
    29821 tctctctact agccatagcc agcctctctt tactcagtct tgcagcctgt gatatggatg
    29881 ataaagacga tcatatggat aatcaaccaa agacaagtca aactagcaag aaagttaaac
    29941 tttcagaaga caaagccaaa tcaattgcgt taaaagatgc ttctgttacg gaagctgatg
    30001 ctcaaatgct atcagttaca caagataatg aagatggcaa agccgtgtat gaaatcgagt
    30061 ttcaaaacaa agatcaagaa tacagctata ccattgacgc caactcaggg gatattgtgg
    30121 aaaaatcttc tgaaccaatc aatgactaat caagaactgt aatgaataag acagccttaa
    30181 ctcttgtgtc caattgtctt tgcctcttag gcgcggctgt ttgataccgt gttgcctttg
    30241 aggcttagtt ctctttatga cccaatgatg actctggatt agcagagtga ttgttgggtc
    30301 ttttgatttt ctttgataag aaagattacc tcgttagaaa tgaggagacg tggttgtcat
    30361 cagtggattt ttcaagatca tctagtggga taagctacct atcttatcag ctttttttta
    30421 gctttaaaaa ttcttgataa tatatttctg ataaaattag ctataataga atcaaatagg
    30481 aaaacgctta cttaaaggag ggtaatgaat gtcgcaagaa aagtatatca tggctattga
    30541 tcagggaaca acaagttcac gagcgattat tttcaatcaa aaaggggaaa aggttagcag
    30601 tagccaaaaa gaattccctc agattttccc acacgctggt tgggtagagc acaatgctaa
    30661 tcagatttgg aattcggttc agtctgttat tgcgggtgct tttattgagt ccagcatcaa
    30721 accaagccaa attgaagcaa tcggaattac caaccaacgt gagaccacag tggtttggga
    30781 caaaaaaacg ggtgtaccta tttataatgc tattgtgtgg caatcacgac agacggcacc
    30841 aattgctgag caactcaaac aagatggcca tacaaaaatg atccatgaaa agacaggcct
    30901 tgttattgat gcctactttt ctgcaaccaa gatccgttgg attttagatc atgttcctgg
    30961 tgctcaagaa cgagctgaaa aaggcgagtt actttttgga accattgata cttggctggt
    31021 ttggaaattg acagatggtg ctgttcatgt gacggattat tccaatgcgg ctcgtaccat
    31081 gctctataat attaaagact taacatggga tgatgagatt ttagagcttt taaatattcc
    31141 aaaagatatg cttccagagg ttaaatccaa ttctgaaatt tatggcaaaa cagctgcctt
    31201 tcatttttat gggggcgaag tgcctatttc aggtatggcg ggtgaccaac aggcagcttt
    31261 gtttggccaa ctagcttttg agcctggtat ggtgaaaaac acttatggca caggttcttt
    31321 cattatcatg aatactggtg atgagatgca gttatcgagt aataatcttt tgaccaccat
    31381 tggttacggg attaatggga aggttcacta tgccttggaa ggttccatct ttattgcagg
    31441 ctctgccatt caatggttgc gagatggtct taaaatgatt gagacttcac cagaatctga
    31501 acagttcgct ctagcatcaa ctagtgacga tgaagtttat gttgtgcctg cttttaccgg
    31561 tttaggagct ccttactggg attctaatgc gcgtggatct gtctttggct tgacacgtgg
    31621 taccagcaaa gaagactttg tcaaagcaac cttacaatct atcgcctatc aagtgcgaga
    31681 tgttattgat accatgcagg tggattcagg tattgacatt caacagctcc gtgtggatgg
    31741 cggtgcagcc atgaataata tgctcatgca atttcaggct gatattttag gaattgatat
    31801 tgcccgtgct aaaaatttag aaacaacagc tctaggagca gctttcttag cagggcttgc
    31861 tgtggggtac tgggaagaca tggatgcttt gaaagagtta aatgccacag gccagctctt
    31921 taaggctagc atgaatgaat cgcgcaaaga aaaattatac aagggttgga agcgcgctgt
    31981 taaagcaact caagttttca cccaagaaga agatgcagat gacgatgcaa aataactaga
    32041 ggaggatgga atggaatttt caaaagagac aagacgctta gctctccaaa aaatgcaaga
    32101 aagagattta gacctactga ttattggggg aggtattacg ggtgctggtg tggcgcttca
    32161 ggcggcagct agtggcctag atacgggtct gattgagatg caagattttg cgcaaggaac
    32221 ctctagccgt tcaaccaaat tggttcacgg ggggcttcgt tacttgaaac aatttgatgt
    32281 ggaggtagtt tcagatacgg tgtcagagcg ggctgtggtg caacaaattg caccccacat
    32341 tccaaaacca gaccctatgt tattacctgt ttatgacgaa cctggcagca cctttagcat
    32401 gttccgtttg aaggtcgcta tggatttgta tgatctttta gcaggcgtgt ccaatacgcc
    32461 agcggccaac aaggtgttaa ccaaagaaga agtcttaaaa cgagaaccag acttaaaaca
    32521 agaaggcttg cttggtggtg gggtttacct tgatttccgc aataatgacg caaggcttgt
    32581 tattgaaaat atcaaacgag ctaatcgtga tggggctctt gttgctagtc atgtgaaagc
    32641 agaagatttc ttgctagatg acaatggtaa gattattggt gtgaaggcgc gtgatctgct
    32701 gtcagatcaa gaaatcatta tcaaggctaa attagtcatc aacaccacag gtccatggag
    32761 tgatgagatt cgtcaattct ctcataaggg acaaccgatt catcaaatgc gccctacaaa
    32821 aggggtgcat ctggtagtgg accgtcaaaa attaccagtg tctcaacctg tctatgttga
    32881 cacagggtta aatgatggtc gtatggtctt tgtcttgcca cgtgaagaaa aaacttattt
    32941 tggaacaacg gacacggact acactggaga cttggagcac ccacaagtta ctcaagaaga
    33001 tgtggattat ttgttaggcg ttgtcaataa ccgctttcca aatgccaacg tgaccattga
    33061 tgatattgaa agcagttggg ctggtcttcg ccccttgtta tcaggtaata gtgcttctga
    33121 ctacaatggt ggcaacagcg gtaaagtcag tgatgatagt tttaatcact tggttgatac
    33181 tgtcaaagcc tatattaacc acgaagatag ccgagaagct gttgaaaaag ctattaagca
    33241 ggttgaaacc agcacatctg aaaaagaatt ggatccgtct gcagtgtcac gaggttcaag
    33301 ttttgaccgt gatgagaatg gactctttac cttggcaggt ggtaagatta ccgactatcg
    33361 caaaatggct gaaggagcat tgacagggat tattcaaatc ctcaaagaag agtttggcaa
    33421 atccttcaag cttatcaatt caaaaaccta tcctgtttca ggaggtgaaa tcaatccagc
    33481 caatgtagat tcagaaatag aagcttatgc tcaattagga actcttagtg gtctttcgat
    33541 ggatgatgct aggtatttgg caaaccttta tggttctaat gcgccaaaag tctttgcctt
    33601 aactcgtcaa ttaacagcag ctgaagggtt aagtttagct gaaaccttgt ccttacatta
    33661 tgcgatggat tatgaaatgg ctcttaaacc gacagattat ttcttgagaa gaacaaatca
    33721 cctcttattt atgcgagata gcctagatgc tttgattgac ccagtgatta atgaaatggc
    33781 taaacatttt gaatggtctg atcaggaaag agtggcacaa gaagacgatc ttcgtcgcgt
    33841 gattgcagac aatgatttga gtgccctaaa aggccagcag gagggttaat atggatatct
    33901 ttggtgaatt tttgggtaca gccttattgg ttttactagg aaatggtgtg gtagcagggg
    33961 ttgtcttacc caaaacgaaa acccatgctt ctggctggat cgtgattgcg actggctggg
    34021 gaattgcagt tgctgtggca gtttttatca gtggcaaagt tgcccctgcc cacctcaatc
    34081 cagctgttag ccttgctttt gccatgagtg gaaccattgc ctggtcaaca gccattgcct
    34141 atagccttgc ccaactattg ggagctatgg ttggttcaac tctggtattc cttcagttca
    34201 ggccacatta tctggctgct gagagtcagg ctgatatttt agggacattt gcgacaggtc
    34261 ctgctattcg agataccagc tcaaacctat tgagtgaaat ctttgggacc tttgtcttga
    34321 tgcttggtat tttggcattt ggcttatatg atatgccagc aggactagga accctctgtg
    34381 taggtacctt ggttattggg attgggttat ccttaggagg aacgacaggt tacgccatta
    34441 acccagcgcg tgatttagga cctcgtctag ttcatgctat tctaccactc aacaacaagg
    34501 gagattctga ttggtcttat gcttggatac ctgttgtagg accaattatt ggagcggcct
    34561 tagcagtttt gcttttccaa gtcatgtcct aaccatcact aaaggggttg gctatcatag
    34621 gccagctcct ttgctttttc tttataggat taggtaaaac gctttcatat cttaaaaaca
    34681 actgctataa taatactatt atgacattaa cgacaaagac catacatgtt atcggggcat
    34741 cctttgctgg tctagccttt gttgataaat ataaggacct caatccagat tcccaaatca
    34801 ttctcattga taaggaaagc tgtcccaatt atattccaaa tggtatcaac caattattca
    34861 gaggagacat tcaagacctg tctgatgcta tgtggggaag ggcctgccta gcagcacaaa
    34921 tagaatctaa ccaccggttt attcaagcag aagtgttagc tatcgaagct ccctcaaaca
    34981 ccttgcttct caaagacagt caaggacgag tttttgaaga aggttatgaa acgcttgttt
    35041 gtgccatggg tgctagcccc cagtctcatt atattgagac gtcacagacc aacaaagttt
    35101 tggtaaccaa atattatgaa gaaagccaag ctagtttaaa actgattgag gctagccaag
    35161 aggtcttggt tattggtgcc ggcttgattg gcttagacct tgcctacagt ttgtccttac
    35221 aaggcaaacg ggtcaaactg attgaagcag ccgaacgtcc agatttctat cagactgacg
    35281 cagaactgat agcccctgta atggcagaaa tgtccactca ccatgtcacc tttattaata
    35341 ataagcgtgt tacggctatc catgagatag agggaaaagt tgtcgctcat accgagcaag
    35401 gggacacctt ccaaggtgat ttggctattt tagccattaa ctttaggcca aatacacacc
    35461 ttttgcaagg acaagtggct tgtgctctgg ataagaccat tttggtcaat gaaaacttac
    35521 agaccagcca ggctaatatc tatgccattg gagacatggt ttcattgcat tttggtatat
    35581 tgggaatgga ttactataca cctttgatta accaagcaat gaagacaggt caggctctgg
    35641 ctctgcattt agctggatat cctattcctc cattacagac ggtcaaggta ttaggaagtt
    35701 ctcactttgg ttattatcgc gcgagtgttg gtgtgacaga agaagaagca gagctttata
    35761 tggatacgtg tagctatttg taccaaaatg gggattctaa aaacctcttt tggctgaaat
    35821 taatagctag aaaaacggat gggattttaa taggcgctca gctcctatcc aaaaccaatg
    35881 ctcttgtcat cgccaatcaa ttaggtcagg ctctggctct gaaagttaca gacggtgact
    35941 tagcatttca agattttctc tttttacaag gtcacagtga tttggcttat catcttcatg
    36001 aagcttgtct caaattattt gaaaagaggc tccgccatga agattgaaga cttaatggat
    36061 aaagaacgaa aagctcaata tcgtctcttg gtgacccttt atcatgctaa agaaacgtta
    36121 aggctaaaag acctaatgag gctatcaaac ttgtctaaag tgaccctatt aaaatacatt
    36181 gacaacctaa atcatttgtg tcgagaacaa ggtttagcct gtcaattact tttagaaaaa
    36241 gacagtctga gcttaaaaga aaatggccag ttccattggg aggatttggt agctctgctt
    36301 ctcaaagaat cggttgccta tcagatattg acctacatgt actgccatga acactttaac
    36361 atcaccaact tatccgttga actgatggtt agtgaagcta ctctaaacag acaactagct
    36421 cacctcaacc agcttttatc agaatttgat ctggcgctct cgcaaggcag acaactggga
    36481 agtgagcttc agtggcgtta tttctatttg gaattgttcc gtcatacctt gaccagacaa
    36541 ggcatagacg ccttggtcaa tcagttagac gcttcgcatt tggctacctt aattgagcgg
    36601 ctgattggcc agtcattatc ggcagaagcc ttagaacaat tattgatttg gttggcgatt
    36661 tcgcaagcgc gaatgtcctt tcaaaaaggc tacaatgatc attttttaag agatagtgac
    36721 tttatgacat ctaatatttt ctttaagcgc ttagaaagca tgcttttaca ttacttaaga
    36781 cgctatgccc ttgaatttga tgcttttgaa gctaagagcc tctttgtctt tttgcatgct
    36841 tatcctctac ttcctattgc cagcatgaag tatagtttgg gttttggagg tcctattgct
    36901 gatcacattt cagaagcctt atggctttta aagaaggctc atgtgattat ccatcagaca
    36961 aaggaggaaa tcatttatgg cttggggata tttttttcca aagcttactt ttttaaagga
    37021 gctatcctta gccaaccaac caatagccaa tacctttatc aattagtagg cgaagataaa
    37081 agagcgcttt taagggttat cataaaccat ttagtgctgc aaatgggtca ggaaacggat
    37141 ttcagtcagc agttgagtga cgacatttta gcattgttgg ttttttccat tgagcgccac
    37201 catgagcctc ttttagtagg gcttgccttg gggcaaaata aggtggaggc agccattgcg
    37261 gaattggcca ttagacgtca tttggggcat cgtagggatt ttcaattaat gccctatgat
    37321 catcaaaaag tttatgactg tctgattacc tatcagactg tctatttacc gagacaagat
    37381 ttaccctatt accggttaaa acagtatagc tccccctatg aactcactgc cttagaagct
    37441 tttctcaaag accttttcca gcaaaaaaat acacgagaag aggaactctc actcagccca
    37501 gcagctaagt ctagttttgc acacaaaact gtgtgatact tggtcttttc taaagactgt
    37561 tacactttta taataataaa gtaggatagt ctaaaggtag atgatttgaa aaagcttatc
    37621 aaatagagct taacaaaatc gaaaattttt ggaggtaaga aatgaaattt ttcctagata
    37681 cagctaatgt agccgctatt aaagcgatta atgaacttgg cgttgtagat ggtgtcacca
    37741 ccaatccaac cattatctca cgtgaaggac gtgattttga aacagttatc aaagaaatct
    37801 gtgacatcgt cgatggccca atcagtgctg aagtgacagg gttaacagca gatgctatgg
    37861 tagaagaagc tagaagcatt gctaagtggc atgacaatgt cgtcgttaaa attccaatga
    37921 ccacagaagg gttaaaagca acaaacattc tttcaaaaga agggattaaa actaatgtga
    37981 ccttgatttt cacagtaagc caaggtttaa tggcaatgaa agcaggcgca acttacatta
    38041 gcccatttat cggtcgtttg gaagatattg gcacagatgc ttatcaatta atcagcgacc
    38101 ttcgtgaaat cattgacttg tacgatttcc aagcagaaat catcgcagca agtattcgta
    38161 caacagccca tgtggaagct gttgctaaat taggcgcaca cattgcgacg attccagacc
    38221 cattatttgc taagatgacg caacatccct taacgacaaa tggattgaaa acatttatgg
    38281 aagattgggc ttcctttaaa aaataaggct aaagagtctg tggccactgt gtcaacaggc
    38341 tctcttatat tcatcgtcaa aaagaattca ccaatgatgt ccaaactagt ttttttctgg
    38401 caaaatagag aaaaagaatt tagggacttt ggaggatttt ctgaaaaaag cgtctatttt
    38461 tgtgatacaa tagacaatag aaaacgttta attttagttg taataaacag agaggtttta
    38521 cttatgacat ttgatgcaat tgaccagttg gcagtaaaca ctgtccgcac cctatcaatg
    38581 gatgccattc aagcggcaaa ttctggacac ccaggacttc caatgggggc agcacctatg
    38641 gcctatgttc tttggaatca cttcatgaac atcaatccca aaacaagccg taattggtca
    38701 aacagagacc gttttatcct atcagcaggt catggaagtg ccatgcttta tagcttgttg
    38761 catttagcag gttatgattt atctgtagaa gatttaaaga acttccgtca atgggcttct
    38821 aaaacaccag gtcacccaga agtgaaccac acagacggtg tcgaagcaac cacaggacct
    38881 cttggtcaag ggatcgcaaa tgccgttggt atggccatgg cagaagctca cctagcagct
    38941 aaatttaaca aaccaggctt tgacatcgtt gatcactaca catttgcttt gaatggtgac
    39001 ggtgacctta tggaaggggt cagccaagaa gcagcaagta tggcaggaca tttaaaactt
    39061 gggaaattgg tcttgctata tgattcaaac gacatctctc ttgatggtcc aacctctatg
    39121 gctttcacag aagatgtgaa aggacgtttc gaagcttacg gttggcaaca tatccttgtg
    39181 aaagatggaa atgatttaga agaaattgca gctgctattg aagcagctaa agctgaaact
    39241 gagaaaccaa ccatcatcga agtcaaaacc attattggtt ttggtgccga aaaacaagga
    39301 acttcagctg ttcacggcgc tcctcttgga gcagaaggca ttgcttttgc caaaaaagct
    39361 taccaatgga ctcatcaaga ttttgaagtg cctgctgaag taacagagcg ctttgctcaa
    39421 ggccttcaag cgcgtggtga aaaagcagaa caagcctgga atgacttgtt tgcagtttat
    39481 gaagcagaat atccagaatt agcagcagaa taccaaaaag cctttactaa cgaagctgct
    39541 caagtagaac ttgaagcgca cgaacttggt agttcaatgg cgagtcgtgt atccagtcaa
    39601 caagccatcc aacaaatctc agaacaagta gcctctttct ggggtggatc agcagatctt
    39661 tcagcatcta acaacacaat ggttaaggct gaaacagatt tccaaccagg tcactacgaa
    39721 ggccgtaaca tctggtttgg cgttcgtgaa tttgccatgg ctgcagccat gaacggtatt
    39781 gcccttcacg gcgggacacg cgtttacggc ggaacctttt ttgtcttctc aaactatctt
    39841 cttccagctg ttcgtatggc agcgctccaa aacttgccaa cagtttatgt catgacacat
    39901 gattctatcg ctgttggtga agatgggcca acgcacgaac caattgaaca attggcaagt
    39961 gttcgctcaa tgcctaactt taacgttatt cgtccagcag acggtaacga aacaaatgct
    40021 gcttggaaac gtgccattgc tgaaacagat cgcccaacca tgcttgtatt gacgcgtcaa
    40081 aaccttccag tgcttgaggg cacaaaagaa ttggcagaag atggtcttaa caaaggagct
    40141 tacatcttgt cagaagccaa aggcgacctt gaaggtatct tgattgcaac aggttcagaa
    40201 gtgaaactgg caatggatac tcaagaagct cttgaagcag aaggcattca tgtgcgtgtc
    40261 gtatctatgc catcacaaaa tatctttgac gaacagtcag cagagtataa agaaagcatc
    40321 ctaccagcag ctgtgactaa acgtctcgct atcgaagcag gttcaagctt tggctgggca
    40381 aaatatgttg gcctagcagg aaaaacattg accattgaca cttggggtgc ttcagctcca
    40441 ggaaatcgta tcttcgaaga atatggtttc actgtggcaa atgcaactga gttatacaaa
    40501 tcactctagg ttacacatcc caaacagagt aaatcaaatg atttactctg tttttttaaa
    40561 ataaaataac cagttctttc ttttcctcaa actgcctaat acacttcttt tgataagaag
    40621 tcattgacaa aacgattcat aaaaattata atttaattgt tattgtatta gcgtaaaagt
    40681 acaaaaaata aaggagtata aatggaaaag aaacgacagc gcttatacga tgtgattaga
    40741 caggcttatg attatccaga aaaccgtgaa aatgtggcct tgtcgcagct acttttagca
    40801 gcttctaata gattaattaa acacagtaac ccacttcttg ttgcctacca actaaaccaa
    40861 gatgtggata attacttact tgataatgac attttacttc caaaatcgct ttgccgtttt
    40921 aagcagtcat tggaaaagta tattttagag gaagcctcat cagtctaggg agaaaaagag
    40981 aagaaaagga aaaaggatac catgatagaa tttaaacatg tttcaaagtt gtatggcgac
    41041 aaagaagctc tcagcgattt aaacgtcacc atcaatgacg gtgaaatttt tggccttatt
    41101 ggacataatg gtgcaggtaa aaccacgacc atcagcattt tgacttctat tatcgaagcg
    41161 agttatggcg aagtatttgt ggatggtcaa cttctgacag aaaatagaga agctatcaaa
    41221 aaacaaattg cttatgtgcc agattctcct gatattttct tgaatctaac tccaaatgag
    41281 tattggcagt ttttagctaa aatttatggg gtgtcagatg aggaccgaga agaacggtta
    41341 gcacagctga caacactttt tgaactgaag gaagaagtta atcaaaccat tgatagtttc
    41401 tcacatggga tgcgccaaaa agtgattgtg attggtgctc ttgtatcaaa tcctaacatc
    41461 tggattttgg atgaaccatt aacaggtttg gatcctcagg cttcttttga ccttaaggaa
    41521 atgatgaaag ctcatgcagc ttctggacat acggtcttat tttcgactca cgtgctatca
    41581 gtcgctgagc agttatgtga tcgtatcggg attctaaaaa aagggaaatt gatttttgtt
    41641 ggaacgattg atgagttgaa agaacaccat cctgacaaag acttggagag catctacctt
    41701 gaactcgcag gtcgtaaggc gcaagaagag gggtgatggg atgaattggt ctactatttg
    41761 ggaacttatc aagataaaca ttctttattc caatccacaa agtttagcta acctcaaaaa
    41821 gcgtcaggaa aaccacccga aagaaaactt caaagcctat aaaagcatga tgaggcaaca
    41881 ggccttaatg attgccatgt ttttggtgat ttaccttttt atgtttattg gtgtcgattt
    41941 cagtcattat ccaggacttt tctcctttga cgttgctatg ttttttatca tgtcaacctt
    42001 gacagccttt agctctcttt acaccatttt ttatgaaagt aatgacttaa aactttatat
    42061 tcacttacca gtaacgtcag aagaactcta tattgcaaaa attgtctcgt cgctagggat
    42121 gggtgctgtc tttttgatgc ctcttatctc tcttctctta attgcctatt ggcaactatt
    42181 gggaaatcct ttgtctattt tagtagctat tgtgctcttt ttagtgttac tagtgagttc
    42241 gatggtatta gctatttata tcaatgcttg ggtgggcaaa atcattgtaa ggagtcgcaa
    42301 gcggaaactc atttcaacta tcatgatgtt tgtctcaact tttggagctt tcgtcttaat
    42361 ttttgcgatt aatattagta acaacaagcg tacgatgacg gatggcgtat ttactgatta
    42421 cccaactatt ccgtatttca aaggattcta tgatgttatt caggcaccgt tttctactgc
    42481 ggccctcctt aacttttggt tgccattgct actgatttta gctatggtat atggtattgt
    42541 cacaaaagtg atgccaactt attatcgtga ggctttttat attagtaacg agaacaaagc
    42601 caagcaaact aaaaaaccag ttaatcgtcc tcatcagaat caatcactga cgcagttgtt
    42661 gcgaaaacat catcttttaa cgttacaaaa tgcaacttta ctgacacaaa cctatctcat
    42721 gcccctgatg tatgtgatgc tttttatcgg tccaagtttg tcacgtggca caggtttctt
    42781 taagcatatt tccccagatt actttggggt ggccttatta tttggggtca gtttgggtgt
    42841 catgtgtgca acaccaacca gctttattgg agtaggtatt tcacttgaaa aggataactt
    42901 tacctttatt aaaagcttac caataacgtt aaaaaaattc ttgctggata aattttgctt
    42961 gctcgtcggt ctgcaactga ttgtgcctat ggtgatttat cttgtgtttg gtctctttgt
    43021 gttgcacctg catcctcttc taacgattgc tttttgtctt ggctacgccc tgtctctgat
    43081 tgtgcaaggg gaattgatgt atcgtcgtga ctaccggctt ctggatttaa aatggcaaga
    43141 catgacacaa ctctttacca gaggaaatgg gcagtggcta acaatgggcc ttatctttgg
    43201 taatttaata gtcacaggtg tagtaggttt tggagctgtt atcattgcca atattatcca
    43261 acaacctctg ttgattagta ttctattgag ttgtctgaca ctaatggttt tagggattgc
    43321 tcacttatgg attcaaaaaa ccttctggaa aagcttagag aagctttaac gaagagagat
    43381 cattattcgg aaaaacagtc ctctggggct gtttttatgc tataatttgg gtatgatgaa
    43441 acgacaattt gaagatgtaa cacgtatcgt aattaaaatt ggcactagtt cattagtgct
    43501 accaacaggt aaaatcaatt tggaaaaaat cgaccaactg gcttttgtga tttcaagttt
    43561 gatgaataag ggcaaggaag ttattttagt atcatcggga gcgatgggat ttggactaga
    43621 tattttgaaa atggaaaaac gtccgaccaa tcttgctaaa caacaggcag tttccagtgt
    43681 tggtcaggtg gccatgatga gtctttattc acaaattttt gcacactacc aaaccaacgt
    43741 gtcacaaatt ttattgacga gagatgtggt ggttttccca gaaagtctag ccaatgttac
    43801 caatgctttt gaaagtctga ttagtttggg cattgtgccg attgttaatg aaaacgatgc
    43861 ggttagtgtg gatgaaatgg atcatgcgac taaatttgga gataatgacc gtttatctgc
    43921 tgtcgttgct ggtattacaa aagctgattt attaatcatg ttgtctgata ttgatggcct
    43981 ttttgataaa aaccctacta tttatgagga tgcgcagtta cgcagtcatg ttgcagtcat
    44041 tacgcaagaa atcattgcgt cagcaggtgg tgcgggcagt aaatttggca caggtgggat
    44101 gcttagcaaa attcagtctg ctcagatggt atttgaaaac aaaggacaga tggtcttgat
    44161 gaatggagct aatcccagag atattttaag agtgcttgaa gggcaaccac taggcacctg
    44221 gttcaagcag atagaagagg taacacatga ctgatatgag aaggttaggg caaagggcaa
    44281 aacaagctag tcttttaata gcacctttgt cgacgcaaat taaaaatcgc tttttaagca
    44341 ccttagcaaa ggcattagtt gacgatacac agactctctt agccgctaac caaaaagatt
    44401 tagcgaatgc taaagaacat ggtatttctg acatcatgat ggatcgcttg cgcttaactt
    44461 cagaacggat taaagcgata gcacagggag ttcaacaggt tgctgactta gctgatccaa
    44521 tcggacaagt cattaagggc tatactaacc tcgatggcct taaaatcctc caaaagagag
    44581 ttcctctagg ggtgattgcg atgatttttg agagtcgccc gaatgtttca gtggatgctt
    44641 ttagtctggc gttcaaaacc aataatgcca tcatcctaag gggaggaaaa gatgcccttc
    44701 actcaaataa agctttggtg aagttgatcc gacaaagtct ggaaaaatca gggatcaccc
    44761 cagatgctgt ccagctagtt gaggatccct cacatgctgt tgctgaagaa ttgatgcagg
    44821 caacggacta tgtggatgtg ttgattccac gtggtggtgc taaattaatt cagaccgtta
    44881 aggaaaaagc aaaagtgcct gtcatcgaaa caggtgtggg gaatgtgcat atctatgtgg
    44941 atgctcaagc tgacttagat atggctacta atattgttat caacgctaaa acaaagcgcc
    45001 caagtgtttg caatgcagct gagggattgg taattcacga agctgtagca gcaaggttta
    45061 ttcctatgct tgaaaaagcg atcaatcagg ttcagccagt agaatggcgg gcagatgaca
    45121 aggctttgcc gttatttgag caggcagtgc ctgcaaaagc agaggatttt gagaccgaat
    45181 ttttagatta tatcatgtct gttaaggttg tttcctcttt ggaagaagct atttcttgga
    45241 taaatcagca tactagtcac cattccgaag ctatcatcac aagggatatt aaggcagcag
    45301 agacctttca agatttagtg gatgctgctg ctgtttatgt caatgcttca acacgattta
    45361 ccgatggttt tgtttttggg cttggtgctg aaattgggat ttctactcaa aaaatgcacg
    45421 cccgtgggcc aatggactta gaagccttga ccagcactaa attttatatt aatggggatg
    45481 gacatatcag agaataagct actagaaggt cccttaatga ctaatgaaag agaaaaagaa
    45541 gaagcaaagg ttgctttaga agaactttta catcagattc aggtgattca tttggaattg
    45601 aaaattgtcc gaaattgggg ctattttgat ctttttggag acggtatgct tgtcagctgg
    45661 atcaaacgtc gaaaaatgag caaggtcaac caattattaa tagacttaca agttactctt
    45721 caaaactgcc gaagatagct ggcagacgtc gataggctat tattagctga cttaccgaat
    45781 atgagttggg ataaaatctt tgatatttgg ttagacaacc tgctgacaga ttgttgtgtg
    45841 attaaagaag ctaaaaattt tttacaagta gttgaaattc tagaggcagc ggctaagtca
    45901 gtgcttgcta agttggctga tagcgaacaa aaagaacaag attagagaag aggaagattc
    45961 ccacgagaat gaaatccttt tctcttactt tttcatttct aaaccttttg aagtatggta
    46021 caattaaagt tatgacaaaa gaatttcatc acgtgaccgt actccttcac gaaacagtgg
    46081 acatgcttga cataaagcct gatgggattt atgttgatgc gacgctaggt ggctcaggcc
    46141 actcagctta tttgttgtcc aaacttggtg aagaagggca cctctattgt tttgaccaag
    46201 accaaaaggc tattgacaat gcacaagtta ccctcaaatc ttatattgac aaaggacagg
    46261 taacttttat taaagataat tttagacacc tcaaagcacg tttaacagcg cttggagttg
    46321 atgaaattga tggtatctta tacgaccttg gtgtttccag cccgcaattg gatgaaagag
    46381 aacgagggtt ttcttataaa caagatgctc cattggatat gcgcatggat cgtcagtcgc
    46441 tcttaacagc ttacgaagtg gtgaatacct atccattcaa tgatttggtt aagattttct
    46501 tcaaatatgg tgaagataaa ttctccaagc agattgctcg aaaaattgaa caagcaagag
    46561 ctattaagcc tattgagaca acaacagagt tggcagaatt gattaaggca gcaaagccag
    46621 ctaaagagtt gaagaaaaaa ggccaccctg ctaaacagat ttttcaagct attcgcattg
    46681 aagtcaatga tgaattggga gcggccgatg aatctattca ggacgctatg gaattattag
    46741 cccttgatgg tcgtatctca gtcattacct tccattctct ggaagatcgc ctaaccaagc
    46801 agttgtttaa agaagctagt acggtggatg tgccaaaagg gcttcctcta attcctgaag
    46861 atatgaaacc taagtttgaa cttgtttcac gtaagccgat cttacctagt cattcagagt
    46921 taacagctaa taaaagggca cactcagcca agctacgtgt tgccaaaaaa attcggaaat
    46981 aagcctatga caaatgaaaa aagaactcag gcagttacaa atgccttgca aaaacgaata
    47041 aaaactttct ctagaattga gaaggctttt tatactgcta tcattgtaac agcgattacg
    47101 atggcagtaa gtattattta cctgcaaagt cgtaagttgc agctacaaca agaaatcact
    47161 agtttaaata gtcatatttc ggatcaaaaa ctagagctta ataatgccaa gcaagaagta
    47221 aatgagttat ctcgccgtga tcgtattata gatattgctg gtaaagcagg cttaagcaac
    47281 cgtaataata atatcaagaa agtcgagtaa tctatgaaaa aatggcaaaa atatgtttta
    47341 gattatgttg tgcgcgatag gagaactcca gtcgaaaatc gcgttcgagt tggacaaaat
    47401 atgatgctct taactatctt tattttcttt attttcatta ttaatttcat gattattatt
    47461 ggaacagatc aaaagtttgg agttagtttg tcagaagggg cgaagaaggt ttatcaagaa
    47521 accgttacga tccaagctaa gcgtgggacc atttatgatc gaaatggtac agctattgca
    47581 gtggattcta cgacttatag catatacgca attttggata aatcatttgt ctcggcttca
    47641 gatgaaaagt tatatgtaca accttctcag tatgaaacag tagctgatat tttaaaaaag
    47701 catctgggaa tgaaaaaaac agatgtaatt aaacagctta agcgtaaagg acttttccaa
    47761 gtctcgtttg gaccgtcagg gtctggcatt tcatatagta ctatgtctac tattcaaaag
    47821 gctatggaag atgccaaaat caagggaatt gctttcacaa ctagtcctgg tcgtatgtat
    47881 ccaaacggga catttgcttc agaatttata ggcttggcat ctctaacaga agataaaaag
    47941 acaggtgtta agagtttagt tggaaaaaca ggtctagaag cttcttttga taaaatttta
    48001 tcaggtcaag atggtgttat tacttatcaa aaagatcgaa atgggaccac actcttgggt
    48061 acaggtaaga ctgtcaagaa agctattgat ggcaaagata tttacacaac gctatctgag
    48121 cctatccaga ccttcttaga aacccagatg gatgtttttc aagccaaatc aaatggtcag
    48181 ttggccagtg caacacttgt taatgctaaa actggtgaaa ttttggcaac aacacaacgc
    48241 cccacttata atgctgatac tctgaaagga cttgaaaata cgaactacaa atggtacagt
    48301 gcacttcatc aaggaaattt tgagccaggc tcaaccatga aagtgatgac tctggcagcg
    48361 gctattgatg ataaagtttt caacccaaac gaaaccttta gcaatgctaa tggtttaaca
    48421 attgcagatg ctactattca agactggtct attaatgaag gcatttccac aggacagtac
    48481 atgaattatg cacaaggatt tgccttctca agtaacgttg ggatgactaa acttgaacaa
    48541 aaaatgggta atgcaaaatg gatgaattat ttgacgaagt tccgctttgg ttttcctact
    48601 cgttttggtt taaaagatga agacgcaggt atatttcctt ctgataatat cgtgactcaa
    48661 gctatgagcg cttttggtca agggatttct gtaacccaga ttcaaatgct tagagccttt
    48721 actgctattt ctaataatgg tgagatgtta gagccacaat ttatcagtca aatttatgat
    48781 cctaacacag caagttttag aacggcaaat aaagaaattg ttggaaaacc tgtatcaaaa
    48841 aaagccgcta gtgaaacaag acaatacatg attggtgtag gaacagaccc tgagtttgga
    48901 acactctatt caaaaacatt tggaccaatt attaaagtgg gtgatttacc tgttgctgtt
    48961 aaatcaggaa cagcacaaat tggttcagaa gatggaagtg gttatcaaga tggtggattg
    49021 actaactatg tctattcggt tgtggcaatg gtgccagctg ataaaccaga ctttttgatg
    49081 tatgttacta tgactaaacc acaacatttt ggtccccttt tttggcaaga tgtggttaac
    49141 ccagtattgg aagaagcata cttaatgcaa gatacactaa ctaagccagt agtatcagat
    49201 gctaatcgtc aaacaactta taaattacca aactttgtag gaaagaatcc tggtgagaca
    49261 tcaagcgagt tgcgtcgaaa tcttgtccag ccagttgtcc ttggtactgg cagcaagatc
    49321 aaaaaagtat cgcatcagcc cggtcaaacg ttaacagaaa accaacaagt tctcatatta
    49381 tcagaccgtt ttgtggaggt accagacatg tatggctgga caaaatccaa tgttaaaacc
    49441 tttgctaaat ggactggaat agacatcagc tttaaaggaa cagattctgg tcgtgttatg
    49501 aaacaaagtg ttgatgttgg taagtccttg aaaaaaataa aaaaaatgac cattacttta
    49561 ggagattaac atgtttttaa cccttattgc agcaatcata tcctttatgg tatctgcttt
    49621 cacaatgcct tattttatca aattctatca attgaaaaaa attggtgggc aacaaatgca
    49681 tgaagatgtc aagcaacatt tagctaaagc tggaacaccg actatggggg gaactgtttt
    49741 tcttttagta gctacggcag tatcgttatt ggttagtcta ttttcgatca aaaacactca
    49801 aagtttagct ttgatttcag gcattttatc aattgttgtc atttacggga ttatcggatt
    49861 tttggatgat tttttaaaaa tttttaaaca aatcaatgaa ggattgacag ccaaacaaaa
    49921 gttagccttg cagttggttg gaggattgat gttctatttt ttacatgtta gtccaagtgg
    49981 catttcctct attaatgtgt ttggttatca gctgccgctg ggaattttct acctattctt
    50041 tgttttgttt tgggtggttg gtttttcaaa tgccgttaat ttgacagatg gtatcgatgg
    50101 cttagcttct atctcagtgg tgattagtct agtgacttac ggcgttattg cctacgttca
    50161 gagtcaattt gatgttttgt tactgattgg agcaatgatt ggagccttgc ttggcttctt
    50221 ctgctttaat cacaaacctg ctaaagtatt tatgggagat gtaggtagtt tagcccttgg
    50281 agctatgttg gctgccattt ctattgcgct tcgtcaagaa tggactctcc tgattattgg
    50341 gatcgtttat gttcttgaaa caagttctgt gatgttgcaa gtgtcctatt tcaagtacac
    50401 caagaaaaaa tatggagaag gtcgtcgtat ttttagaatg acgcctttcc accaccattt
    50461 ggaattggga ggcttgtctg gtaaaggcaa gaagtggtca gaatggcagg tagatgcttt
    50521 tttgtgggga gtaggaagtc tagctagttt actagtttta gctatcttat acgtgttcta
    50581 agggggatta tcaagaatag tcaccaatag cattttgatt aacatcatca ataagagagt
    50641 ggagatgacc cacaaatgct gattttgtga gtgttgtccc actccttttg cttgtctcta
    50701 acaataatga tataatatgg aagaaaacga ggtaaaacat gtcatttaaa gattatcatt
    50761 ttaagcaata cgttcagcaa gcgctggaag aaattggctt tgtcaatcca acagaggtcc
    50821 agaagcggct gattcctatt gttaactccg gtcgtgactt agttggggaa tcaaaaacag
    50881 gttcagggaa aacccacacc tttttgttgc ccatttttga aaaacttgat gaagctaaag
    50941 cagaagtgca agtcgttatt acagcaccta gccgtgaatt agcaactcaa atttttgatg
    51001 cttgtaaaca gattgctaag cacttccaag aagagattcg tttggccaac tatgttggag
    51061 gcacagacaa actccgtcag attgaaaaac taaaaggcag ccagccgcat attgtcatcg
    51121 gaaccccagg tcgtatttat gacttggtca agtctggtga tttagcgatt cataaagcaa
    51181 cgacctttgt tgtggatgag gccgatatga ccatggacat gggctttttg gatacggtag
    51241 ataagattgc agcttcgctt ccaaaatctg ttcagatttt ggtgttctca gcaactattc
    51301 cacagaaatt acaacccttt ttgaaaaaat acttgaccaa tcctgttatt gaacaaatca
    51361 agacaaagac cgttatcgca gataccattg ataactggct tgtgtcgaca aaagggcgtg
    51421 ataagaatgg tcaactgtta gagattctca aaaccatgca gccttatatg gctatgcttt
    51481 ttgtcaatac caaggaacgc gcagatgatt tgcatgcctt tttaacagct aatggcttaa
    51541 aagtggctaa gattcatggg ggcattcctc caagagaacg taagcgcatc atgaaccaag
    51601 tcaaaaaact ggactttgaa tacattgttg ccacagactt agcagcgcgt gggattgaca
    51661 ttgaaggggt cagccatgtg atcaatgacg ccatcccaca agacttgtct ttctttgtcc
    51721 atcgtgtagg ccgaacaggt cgaaatggta tggcaggaac tgccattaca ctttaccagc
    51781 caagtgacga ctcagatatc aaagagctgg aaaaaatggg gattgccttt acaccgaagg
    51841 tgctcaaaaa tggagaattt caagatacct atgaccgtga tcgccgtcaa aaccgtgaaa
    51901 aagcctatca aaaattagac acagaaatga ttggtttggt caaaaagaaa aagaaaaaag
    51961 tcaaaccagg ttacaagaaa aaaattcagt gggcggttga tgaaaaacgt cgcaaagaac
    52021 gtcgtgctga aaatcgtgct aagggccgcg ctgagcgtaa ggccaaaaaa caacattttt
    52081 aagaacaaag agcaagcaag tgatcaattg gcatctaatc ttgctttttt tacacctgct
    52141 acttgtattg tttaccattt gttaacacaa aaagtgatca tagcttttgc ttattgctat
    52201 aatacggatt tactatttta catgtgggtc taagagtgtt agaatattaa gacaaacaaa
    52261 tacaaagggg aaatacatga catcagtgtt tttaaccagt ggttgggctt tttatgatta
    52321 cctcatctca ccgattccac atggaaaact ttttagttgg catgctgttt ttgatgccat
    52381 tccaaatatt atccaacggc ttccaattac gcttggtttg acactatcag gagcaacctt
    52441 tggcttggtt ttggctttga tttttgccct tgtcaaaatt aataaagtga agctactata
    52501 ccctattcaa gctatttttg tgagtttctt gcgaggaact cctattttgg tacagttgat
    52561 gttgacctac tacggtattc ccctctttct aaaatttctc aatcagaagt atggctttga
    52621 ttggaatgtt aatgcaattc cggcttctat ttttgccatt acagcctttg cttttaatga
    52681 agcagcctac gctagtgaaa ctattcgggc agccatttta tcagtagata caggtgaaat
    52741 tgaagcagca aaaagtctag gcatgacttc tgtgcaggtt taccgtcgtg tcattattcc
    52801 taatgcaact gttgtggcta ttccaacctt gattaatggg ttaattggct taactaaagg
    52861 aacatcgctt gcctttaatg cagggattgt cgaaatgttt gcccaggctc aaattctagg
    52921 cggatcagat taccgttatt ttgaacgtta tatctctgtt gctcttgtct attggtctat
    52981 cagtattttg atggagcaag taggtcgctt gattgaaaac aagatggcca tcaaagcacc
    53041 agaacaagct agaaatgaaa agttaggaga attgcgttga tgattacaat tagaaatttg
    53101 agcaagacat tctcagggca aaaagtttta gatagtttgg ctcttgatat tgaaaaaggt
    53161 caagtgattg ctttagttgg tgcttcagga gcagggaaat cgaccttcct tcgtagccta
    53221 aactatttgg aaaaaccaga ttcaggatcc attagcattg gtgactttac ggttgatttt
    53281 gagaccatta ccacagagca agtccttatt ttacgtcgga aacttgccat ggtttttcaa
    53341 caatttaatc tttttgagcg tcgtacagcc cttgagaatg tcaaagaagg tcttaaggtg
    53401 gtcaaaaaac tgtctgacca agaagcgact aagctggcgc aagcagaatt ggctaaggtt
    53461 ggtttagcag atcgaaaaca tcattaccca cgtcatttat cagggggaca aaaacaacgg
    53521 gtagctttag caagagctct ggctatgaaa ccagatgttt tattactaga tgagccgacc
    53581 tcggctcttg acccggaatt agttggcgaa gtggaaaagt ctattactga tgctgctaaa
    53641 tccggacaga ccatggtttt agtgagtcat gacatgaatt ttgtttacca agtggcagat
    53701 agagtactct ttttagatca agggaaaatc ttggaacaag gaacacctga agaagtcttt
    53761 agacatcctc aaaaagaacg aaccaaagaa ttttttgcaa gctattcaaa aacatacatt
    53821 taatgatatt cttttgttat aataaaaagg tctaggtatt cctgggcttt tcttgttatg
    53881 ttttttagaa aaacttatgg gaaagaaata atgactaggt ggaaatatgt tagtagaaat
    53941 ctttagcctt tatgtaaaag gtctcattct ctcaagcctt actatgattt taatttgttt
    54001 aatatggact ttatggcgag caaaaaccaa aagagataaa acattgattg aaagacaagc
    54061 ttttctttat gagatgctaa tggttgctat tttaaccatc ccaattttat cgtttgcttt
    54121 tatgagtatt ttggttgtca taaaatccta atcattgcaa gaagggatta tcattgctaa
    54181 aatattggca agagtagatt aaaggagaaa aatcatgtac gatacattaa ttattggttc
    54241 aggaccagca ggaatgactg ccgctttata cgctgctaga agtaatttat ctgttgccat
    54301 tattgaacaa ggggcacctg gtggtcagat gaacaacact tttgatatag agaattaccc
    54361 gggatatgat catatatctg gaccagaatt agctatgaaa atgtacgaac ctttagagaa
    54421 gtttaacgtt gaaaacattt atggtattgt tcaaaaaata gaaaattttg gtgactataa
    54481 gtgtgtgttg actgaagatg ctagttatga agctaaaacg gttattattg caacgggagc
    54541 taaataccgt gtactaggtg ttccaggtga agaatactat actagtcgag gagtttctta
    54601 ttgtgcagta tgtgatggtg cgtttttccg tgaccaggat cttttggtcg ttggtggtgg
    54661 tgactcagca gttgaagaag ctatttatct tactcagttt gctaaaaagg taaccgttgt
    54721 tcatcgccgt gatcaactaa gagctcaaaa aatactgcaa gatcgtgctt ttgccaatga
    54781 taaggtcgac tttatctggg attcagtcgt caaagaaatt caaggcaatg atattaaggt
    54841 ctccaatgtc ctaatcgaaa atgtgaaaac aggccaagtc actgaccacg cttttggagg
    54901 tgtgtttatc tatgttggta tgaatcctgt gacaggtatg gtaaaggatc tagaaattac
    54961 cgatcaagaa ggttggatta tcacagatga tcatatgagg acaagtattc ctggtatttt
    55021 tgcgattgga gatgttcgtc aaaaagacct tcgccaaatc acgacagctg ttggagatgg
    55081 tgcaattgca gggcaaggtg tttatcacta ccttgaaagt ttcccttcat aaggttaaaa
    55141 ctccttcatt tttccttgtc tttcccttaa aaaagctaaa ttgcataaga cctttaagaa
    55201 atataaagaa cagttttcct taatatcttt cctagataaa tgttgaaaat tttctgaaaa
    55261 aaggatataa taaatagtat tttagtgaat ggagtttaga atgtctataa aagaacaaac
    55321 agacaataac gaactagaaa atggaatggt aaggggctta gaaaatcgtc atgtgcagtt
    55381 aattgcgatt gcaggaacga ttggaacagg tctcttttta ggggcaggac gctctattgc
    55441 cctaacagga ccatctatta tttttgtgta tatgattaca ggtgccttca tgtttatgat
    55501 gatgcgtgcc atcggtgaaa tgctctatta tgatccagat caacacacct ttatcaattt
    55561 tatttccaaa tacattggtc caggctgggg ttatttttcg ggtctatcct attggatttc
    55621 ccttattttt attggaatgg cagaaatcac agcagtaggt gcttatgtgc aattttggtt
    55681 cccaagctgg ccagcctggt tgattcagtt ggttttctta gtcttactta gttcgatcaa
    55741 cttaattgct gtgcgcgttt ttggggaaac agagttttgg tttgccatga ttaagatttt
    55801 agctatttta gctttgattg caacagctat tttcatggta ttgacaggtt ttgaaactca
    55861 cacaggccat gctagccttt ccaatatttt tgaccatttt tccatgttcc caaatgggaa
    55921 actaaagttc tttatggcct tccaaatggt tttctttgct tatcaagcta tcgaatttgt
    55981 gggaattacc acttctgaga cggctaaccc aagaaaagtt ctaccaaagg ctattcaaga
    56041 aattccaacc cgtattgtga tcttttatgt gggagccttg gtctctatta tggcaattgt
    56101 gccatggcat cagttaccag ttgatgaatc tccttttgtg atggtgttca aattgattgg
    56161 tattaaatgg gcagcagcct tgattaactt tgtggtcttg acatcagcag cgtcagcgct
    56221 taactcaacc ctttattcaa ccggtcgtca tctctatcag attgctaatg agactccaaa
    56281 cgctttgacc aatcgcttaa agattaatac tttatctcga caaggggtgc caagtcgtgc
    56341 cattattgct tcagcggttg tggttggtat ctcagctttg attaatatcc taccaggagt
    56401 tgcagatgcg ttctcactca ttacggcctc ctcatcaggt gtatatattg ctatctacgc
    56461 cttaaccatg attgctcact ggaagtaccg tcaatctaag gactttatgg cagatggtta
    56521 tttgatgcca aaatataaag tgacaacgcc tttgaccctt gctttctttg cttttgtctt
    56581 tatctctctt ttcttacaag aatccaccta tatcggcgcc attggagcaa cgatttggat
    56641 tattgttttt gggatttata gcaatgtcaa atttaaataa taattagcga tatagaactg
    56701 aatccattaa ctctttctta tttgaggatg tcatgatgga tcagttcttt ttttacttta
    56761 gcgataactc aagttatttc taaaccctag ccaaagagtc ctttttaaaa tatgttataa
    56821 tagtaacaat aattcaaagg agtccccttt atgtataaag atgatagttt aactctccat
    56881 actgatttgt atcagattaa tatgatgcaa gtttattttg agcagggcat tcataatcgt
    56941 catgcggtgt ttgaagtcta tttccgcaag gaacctttta acaatggtta tgctgttttt
    57001 gccggtttac agcgcatggt ggagtatcta gagcaatttc aattttcaga aacagatttg
    57061 gcttaccttg aagaactggg ttatccagga aactttttga cctaccttaa agagttacga
    57121 ttagaattga ccatccgttc agctaaagaa ggagatttgg tttttgctaa tgagccgatt
    57181 gtgcaagtag aaggccctct aggtcagtgt cagttggtcg aaacagctct tttaaacatt
    57241 gttaacttcc agaccttgat tgctacaaag gctgctcgta ttcgttctgt gattgaggat
    57301 gaaccccttt tggaatttgg tacccgtcgt gcacaggaac tagatgctgc gatttgggga
    57361 acccgcgcag cgatgattgg tggagcagat gcaacaagta atgtgagagc aggtaaacgc
    57421 tttgatatcc ctgtttcagg tacgcatgct catgctttag tgcaagccta tggtaatgat
    57481 tatgatgctt tcatggctta tgctaagacc cataaagatt gtgtatttct tgttgacacc
    57541 tatgacacac ttaaagtagg tgtgccaaca gctatccgag tagccaaaga aatgggtgac
    57601 aagattaatt ttctaggtgt tcgattggac tctggtgact tggcttacct ctcaaaaaca
    57661 gtccgtcagc agttagacga cgctggtttt accgaggcta agatctatgc ttctaatgac
    57721 ctcgatgaaa ataccatcct caacttaaaa atgcaaaagg ccaaaattga tgtttggggt
    57781 gttgggacca aactgatcac agcctatgat cagcctgcct taggtgctgt ttataagatt
    57841 gtctctattg agcaagaaga tggtagcatg cgtgatacga tcaaattatc aaataatgca
    57901 gaaaaagtat ccacaccagg taaaaaacaa gtttggcgca tcaccagtcg tgaaaaaggc
    57961 aaatcagaag gcgactatat cacgtttact gatattaatg ttaatgaatt aactgagatt
    58021 gagatgttcc atccgaccta tacctatatt aagaaaaccg tcagaaattt tgatgcaatt
    58081 cctctcttag ttgatatttt tgtcaaggga gaattagttt accagctacc gaccttatct
    58141 gaaatcaaga cttatgctaa aaaagaattt gacaagcttt gggatgaata caagcgtgtc
    58201 ttaaatcctc aagactaccc agtagacttg gcacgagatg tgtggcaaaa taagatgacc
    58261 ttgattgata acattcgtaa agatactcat ggaaagagtg aatgacatga cattacaaga
    58321 agagatcatt cgacaattag gcgtcaaggc tagcattgat ccacaagaag aaattcgaaa
    58381 aaccgttgat tttttaaaag cttatttgcg aaagcactca tttttaaaaa cttatgtctt
    58441 aggcatttct ggaggtcagg attctaccct cgcaggaaag ctagcccaga tggccattgc
    58501 agagttacgg gaggaaacaa gtgataaagc ttaccaattt atagctgttc gcttgcctta
    58561 cggggttcag gctgatgaag cagatgcgca aaaagccttg gcttttattg caccagatca
    58621 gacccttacc attaatatca aggcagctgt ggacggtcaa gtagaggctc tacaagcagc
    58681 aggcgttgag atttctgatt ttaacaaagg taatattaaa gcacgtcagc gaatgataag
    58741 tcaatatgcc attgctggcc aaatggctgg tgctgttatt ggaacggatc atgcggcaga
    58801 aaacatcact ggtttcttta ctaaatttgg tgatggtgga gcagatattc ttcccctctt
    58861 taggcttaac aaacgtcaag gaaaggctct tttgaaagtt ttaggagcag atgctgcttt
    58921 gtatgaaaaa gttccaactg ctgatttaga agatcaaaaa ccaggcttgg ctgatgaggt
    58981 tgccctaggg gtgacctatc aagacatcga cgactatttg gaagggaagc tgatttccaa
    59041 agcagctcaa gcaactattg aaaaatggtg gcataaagga caacacaagc gtcacctgcc
    59101 aatcaccatt tttgatgatt tttggaaata agaaatgatg ttcaaagagt aaaaaaagaa
    59161 aacaaaaaaa gttaggttat cctaactttt ttcttgaaga aaatcaaata aggtctataa
    59221 tagaagtaat cctttagaat agaatggctg gataataacc atcttgccaa tattatttca
    59281 ggtgaagctt atcttaatat tttaggagga caataatgtc agcattaaca gagacattta
    59341 cagaacaatt atttgctcat tacgaagcca atgcaaaatt ttcagctatt gagaatgccg
    59401 ttacgcataa tggtttgcta aaatcattag aaacccgtca aagtgaagtg gacaatgatt
    59461 ttgtgttttc tattgattta actaaagata aggtatctaa ccaaaaggca tctggtcgct
    59521 gctggatgtt tgctgccttg aacactttcc gacacaaatt aatcacagag tttaaattag
    59581 aaaattttga actgtcacaa gcccatactt tcttttggga taagtatgaa aaagctaact
    59641 ggtttatgga gcaggtcatt gctacagctg accaagaatt aaccagtcgt aaagttaagt
    59701 ttctcttgga tgttccacaa caagatggtg gccagtggga catggtggtt tccttgtttg
    59761 agaagtatgg agtggtgcca aaatctgttt acccagaatc aatctcatca agtaacagtc
    59821 gtgaattaaa ccagtatttg aataaattat tgcgccaaga tgctcaaatt cttcgtgacc
    59881 tgattgcatc aggtgctaag gcagaccaag ttgaggatcg aaaagcagag cttcttcagg
    59941 aaatttttaa cttcttggcc atgacccttg gtttaccacc tcgtcatttt gattttgcct
    60001 accgtgataa agatgaccac tatcatgttg agaaaggttt gacaccgcaa gcgttttacg
    60061 acaaatttgt tggcttaaag ctttctgatt atgtgtctgt tattaatgca ccaactgctg
    60121 ataagcctta tggcaaatca tacactgttg agatgctagg aaatgtggtc ggtagtcgtg
    60181 aggttcgcta cctcaacctt gatatgaaac gtttcaaaga actagctatc aagcagatgc
    60241 aggctggtga gtccgtttgg tttggctctg atgtgggtca agtttcagat cgtcaaaaag
    60301 ggattttggc aactaatact tacgattttg aagctagtat ggatatcaat cttagtcaag
    60361 ataaggctgg acgtttggat tatagtgaaa gtttgatgac acatgctatg gttttaacag
    60421 gtgttgactt agatgaaaca ggaaaaccgt taaaatggaa ggttgaaaat tcatggggtg
    60481 agaaggttgg tgacaaaggt tactttgttg cttcagatgc ttggatggat gaatatacct
    60541 atcaaattgt tgtccgtaaa gaattcttaa cagctgacga gttagcggct tatgaaaaag
    60601 agccacaagt actagctcct tgggatccaa tgggtgcttt agcacaatgc taattccttt
    60661 ctttgcgact gtatgaaatc taaaggctgg acaaaacgaa cagcaaacgg attggactcc
    60721 gcataagaaa gtgaacatga aaaaaattat tatgctaaga aaatgacata tgaaaaaaca
    60781 cgtcttcggt atatggaaac gtgttttttc atgtttactc tcttatggca ttagttgcta
    60841 tttataacaa ttttaaataa gtctattttg ttttaggtta acgtttgaaa aatcagttgc
    60901 taattccctt aacgttgtac cttttcttta atacgattaa agaattctgt tttttgtttt
    60961 atattgtatg tggtaagtca tttgtgtcat ataaaaacga gtcctcacag aacgtggact
    61021 cgctttttat ttagattatc acttaaggta gatattaaaa gtaactaaat ggatatgtaa
    61081 taaaaggtag gtacagacaa taagtagagt tagagattaa tgagttgtct ttttatcatc
    61141 ggtagatgga tgattgctat tgttgtctgt attggttgaa ttacttatat cattgctact
    61201 actagtatca tctgaagtca tttggctaga agctgttgtc gtgttattgc tgtaaagatt
    61261 gttgtaaacc gaattagtat agtcggtgtt gctcgcatag gttccgctta agtagaggaa
    61321 tccaccactg cgataaagac catttggcat cgtccaatct tcactgtaac catttgttaa
    61381 gtaagtcatc atgctacgat aaacgtcaga tgcaatctct agacttgatc cgtatactgg
    61441 ggtcaagcgg tttttgtaac ctgtccaaac agccatggcg tagcgcttag taaagccaac
    61501 aaagttttcg tctggcgcta atgtaccaac ataatctgga taaaggccgt atttttcacc
    61561 aattttagct agttcctcat cagtgtagtt agaagtccct gttttaccag cttgcgcaac
    61621 accaggaatg gcagcagcag tacctgtacc ataagtgaga acagttttta acatatctgt
    61681 catcatatag gccgtggttt ctttcatggc acgttttcct ttttcatcaa aagttttact
    61741 tgtaccatca ctaaattcca ctttattgac ataccttggt ttatgataaa taccaccatt
    61801 tgcaaaagca gcgtatgcag cggccatttt ttcactactt gcaccatatt ttttatctga
    61861 gctactgtta ttacttgaga tagcgtttga gtagtgcatt tcgggatagt taatacctaa
    61921 actgcttaag aaagatcgag catagtcaag tcctgcggct tccagtgctc ggactgctgg
    61981 gacatttcgc gatagcataa tagcagcttg gattgtcatc catccgttat atctaaggtc
    62041 ccagttaaac aattgggtag tggttccagg ccaataatag actgagtcat tagtcgactg
    62101 agcagtagaa gtataaacac cagattcaat agcaggagca taggctgtga ttggcttcat
    62161 ggtagaaccc cagtcacgat cagttaaaac agcttggtta gtcccaaatg aaacattttc
    62221 atcttgatta cgtccgccaa gctgagcaat aacatgacca tttgtcacat caacaatcgt
    62281 tgaagcaact tggaaatctt ggtctggata gtaaacataa tcaccagaat gataaatatt
    62341 ataaagagtc tgctgcgcat cggggataat attggtataa acttttaaac cagcggtaaa
    62401 aatatcttta ttcgtttctt ttttgacttc ttcaataact tgttttagat aattatccat
    62461 atattttgga taagttgagc gctgttggag tgattgtaga ccttcagcga cgggagttgc
    62521 gatggcagtt tcatattctg ctttcgtcag atgtttttcc atgtacatct gttgcaacac
    62581 gacgttacgg cgattttgag cagcttcagg atgaaggtaa ggatcatatt gactaggagc
    62641 ttgagggatt ccagccaata gggctagttg ggcataagat aaatccttaa gatccttgcc
    62701 ataataagac ttagcggctg tcagcatacc atagttgcca ttacccatat atactttgtt
    62761 gatgtaaaaa gtcaggattt cttgtttagt atattttcgc tccatttgaa gagcaagcca
    62821 aacttcttga gccttacgtt ttaaggtttg atcagattca ttagtagaaa aataggctag
    62881 tttaatgagt tgctgatcaa gcgttgaccc cccttgagtg gtctgactcg ttagattatg
    62941 aaaggcagca ccaaaaatac gataaagatc tactccacga tggttaaaga aacgtttatc
    63001 ttcaattgag gtaatagcat taactagatt aatagggata ctatcagctg ttacattttc
    63061 acgcttttca gaacccaaat cagcaatcag attgttatta ccgtcataaa ccaagctaga
    63121 gtttgttgat tttaactggg cttctgacag tttcggagca ctgctaatgt agaaggtaaa
    63181 caaaagacca ccaataataa taacaaggat aataaggcta agaattgcac ttaatacata
    63241 ctttagccac ttaaggattt ttggattttt aattgtaatc accgcctaaa aaattttgtt
    63301 caattatgtt taaataaggg acttgtggaa aggctccaaa tgctacctta aagccatttt
    63361 ttctgatata atcaatgggc atcgatttac tgccattatc tatctgataa aatgaaatca
    63421 aggcttgagc aggtaggtag taagtctcct tcagtgtgga aaagtgaaga aggacaaagc
    63481 agattccttt ttgatgtaaa acgcaagcca tatgttcaat ctgatgtaaa tggaaatttt
    63541 tcatgggcat agctgttttt tgcctggttt cttttgcttc aaaatcaaca taatgtcctt
    63601 tataaacgcc gcaatagtca gtcgttgaag cttgtctaaa gtacgcttca acgatttttg
    63661 cccgactgcg tttagggtaa tccactttga caatttggac aggagtaggt tttttgtgaa
    63721 tgacagctat ttgacgagat aaataataat catttgtcgc gttgatagca gcttcaaagg
    63781 acatacctct attggcgaag tccaccttat tttgctttgt ttgcttttga acggaactta
    63841 ctttttgtcg aataagatta tgaggataat taaccattgt tctcctaata ttatctagtt
    63901 aatgctaaaa atttaagcac ttttattata acatattttt tgaaaggata acacctaatg
    63961 actgcgattc taattacagg ttaccgaagc tttgaaatag ggatttttga ccataaagac
    64021 ccacgagttt caattattaa acaggctatt cgtaaagatt taataggtta tttggaaaat
    64081 ggtgtggatt ggtttatctt tacagggaac ttgggttttg aacaatgggc tttggaagta
    64141 gctaatgagc taaaagagga gtatcccttg cagatagcta ctatattctt gtttgaaacg
    64201 catggagata ggtggaatga aaaaaatcaa aaagttttaa gtcagtttag ggctgttgac
    64261 tttgtaaaat attactttcc aaattacgaa caaccgacgc aatttagtca atattatcag
    64321 tttttattag aaaagacaga aggggcttat gttttttatg acacagaaaa cgagaccaac
    64381 ttaaaatatt ttctcaagaa agcaaaagat atgccgcatt atcagttgct attgctaacc
    64441 tttgatcggc taaatgatat gtcacaaagc tagcattgta tttttagggg tattggtatt
    64501 taaatacttg ctttttgaac tatttttctg tatcattaat aataatactg aaatataatt
    64561 ttggtaaaaa gattgaccgt tcggagagta aagaatgaca agtattattt atagtcctaa
    64621 agatattttt gagcaagaat ttaagactag tatgcgaggg tttgataaga aagaagttga
    64681 tgaatttctt gataatgtaa ttaaagatta tgaaaatttc aatgctcaaa ttgaagcttt
    64741 aaaagctgag aacgaagcct taaaaaaggc caagtttcaa gctagaaata cagtttcagc
    64801 gactgttcaa caaccagtac cgcaaccgac tcgtgttgct caatcagcta ctaattttga
    64861 catcttgaaa cgtattagta aattggaaaa agaggttttt ggtaaacaaa ttattgagta
    64921 atgaaaactg tgcaattttt ggataatcgc gtagtatttt aatactatga ggaaagtcca
    64981 tgctagcact ggctgtgatg ccagtagtga ttgtgctagg cgaacacata agcctaggga
    65041 tgtgcataca cattacggcg aaggaaatgg ctaagtcgtt tgatatgcca aagtacttct
    65101 gaaagtgcca cagtgacgta gtttttatgg aaacgtaaaa aatggaacgc ggtaaacccc
    65161 tcaagctagc aacccaaact ttggtagggg catgggatag ttggaaacga acaagctatc
    65221 ctgactgtca acagacggta gacagatgat tatcgaagga aataattcct agttatttcc
    65281 ggaacaaaac atggcttata gaaaattgca taataggtta agctagcact tgctagcttt
    65341 tatttgattt aaaagaaaga gatatatgaa agaaacattt agattagtcg caactgcagc
    65401 cgcaggttta gaagctgtcg ttggtaaaga agtcagagca ctaggttttg attgtcaggt
    65461 tgaaaatggg aaagtttatt ttgaaggtga tgtagaagcg attgttaaaa caaatctttg
    65521 gttacgtgca gcagatcgta tcaaaattat cgtaggacaa tttcctgcta gaacctttga
    65581 agaattattc caaggtgtct ttgccttgga ttggggaaat tatttaccgc taggagctaa
    65641 gtttccaatc tcaaaagcca agtgtgtcaa gtcaaagcta cacaatgagc caagtgttca
    65701 ggcgattacc aaaaaagctg ttgttaagaa actgcaaaaa catttccaca ggccagaagg
    65761 agttcctctt caagaagttg ggtcaacgtt taacattgag gtatctattt taaaagacca
    65821 agccactatt atgattgaca cgacaggatc tagcctattt aaacgagggt accgcgttca
    65881 aaagggtggg gctcctatta aagaaaatat ggcagctgct atcttggcct tatctaactg
    65941 gtttccagat aaacctctgg ttgatcccac ctgtggatcg ggaacgtttt gcatcgaggc
    66001 agccctgatt gggatgaata ttgctccagg atttaaccgt tcgtttgctt ttgaagaatg
    66061 gagctgggta gataaagaca tggtgcaaca agttcgtgat gatgccgaac aagaagctaa
    66121 ttatgaaatc gaattagata tttctggctt tgatatcgat ggccgcatga ttgagattgc
    66181 taaaagtaat gctgaagaag ctggtttatc tgatgtgatt acctttaagc aaatgcgtct
    66241 gcaagacttt cgaacagaca aggttaatgg tgtagtgata tcaaatcctc cttatggaga
    66301 acggttgctt gatgacaaag cggttgacat cttgtataat gaaatgggac aaacctttgc
    66361 accattgaaa acatggagca aatttatcct tacaagtgat gaactttttg aactaaaata
    66421 cgggcaaaaa gctgataaaa aacgtaaact ttataacggc accctaaaag ttgatttgta
    66481 ccaattttat ggggaaaggg taaagcgaca tctgatatag agaggtagta agcgtgtcag
    66541 aagaaagcaa agaagtcgaa gtaacaaaag aatcgcaaac attggggctt aatgaagcca
    66601 agtcaatgac aattggtgaa gctgtacgca aacagtcaga gataaaagca ggtgttacta
    66661 aggatgatag tattttagat aagtacatta agcaacaccg tgacgaagtt tcttctcaaa
    66721 agtttgatgc taagtataca gagcttgata cagctagttt agataacttt atcaaaaaac
    66781 aaagagaagc attgagtaaa gccggtcttg ttgatgacga acctgtgtct gcggagtctg
    66841 ctgagcaaga tagcactttg gttgaagaag tagctgaaga cttagctcca atggagacta
    66901 ctgcggtggt aactgggatt ccggtggaag cgacagtccc tgtgttagat ctagatccat
    66961 cagagagggt cattccagaa ccacagatga ccaaggaaga gccaaaaaga gatcagtttc
    67021 tttctgaaga tagccaccat ccagccaaac aaaacacgaa aaaaggttgg ttaatagctt
    67081 tatttctact attattggcc attcttgcag ttgtatttgg ttggaaccat ttcttgagac
    67141 aagacagtgg taaaacaact caaacagcaa gtaaacagac aaagacctct ttgcagaccg
    67201 acagtgctaa aaaagcaacg cgcttgaagg ctgctgctaa agctttcgaa aaacaatatg
    67261 gtacttttta tacagatgcc acaaagagca aattaaaaaa tagtgccttt gctactttgc
    67321 cagatttaga agctgccttg aaagctttgg aaggctctgc ttactatgat aaggcgaaag
    67381 caaaagtcga ttcccttaag aaagctattg ctgctattac agcggttaac ggtaaatttg
    67441 tttccgatgt tgttgtagat ggtgaaaagg tttcggctga agtcaaggct gatgctaatt
    67501 ttgatgattt atcaagtgca accttgacaa caggaaatgc aaatcttgat gctgtcttgc
    67561 aggcaagcat cacagaaggt cgtcagcaac tagccagcaa ggctgaggcc gctaaagcag
    67621 ctaatgagca agcagcccag gctcaagcag ctcaaggaca aagtacatca gtagcaccat
    67681 ctggctatgg cttgacaagt tatgaccctg caagcttaca acggcattta tcacgtgtac
    67741 cttacaatca agatgttatt gctgacagag ctaacccatc ttgggcattt aatccaggag
    67801 ttcttgaaaa aattgtagca acctcacaag ctagaggtta tatttcaggc taccaatata
    67861 ttttagagcc ggttaatatt attaatggca atggttacta taatatgttt aagcctgatg
    67921 gcacttatct gttctctatt aattgtaaga cgggttattt tgtaggaaat ggcaaaggtt
    67981 atgctgatgc tttagattac tgagaaaatc aaaaaaaact gagataaggc aacttgtctc
    68041 agttttttga ttaataaagt atgttgtctt aaaatctgca gatagacttg ttttttgtaa
    68101 caagtcaaat aggtcagtag gattgttatg tttgacaaca cactagtatc agatgacatg
    68161 gcgactaaaa ggatcgtctg aaatcccttg atcaataatc aattgagccc attctttggc
    68221 ggcaaagagg ctatgatcct tatagtttcc acaggattca agagttgttc caggaacatc
    68281 ttcccaagta atcccagttg caatttcttc taggctggat ttaatcacct tggcaatatc
    68341 agtagaactg tgttttcccc acatgataag gtgaaaacct gttcgacagc caaaaggaga
    68401 gcaatcaatc atcccatcaa tgcgttggcg gatgagcttg gcaagtaagt gttcaatggt
    68461 atgcaaaccg gctgtttcaa tagaattttg gttaggctgc actaggcgaa catcaaaatt
    68521 tgtaatacga tcgcccttgg gtccaaattc ttcagaaata agacgaacat aaggggcctt
    68581 tacaatagta tgatctagct caaaactttc gacgataact tcttttgtca tttcaatctc
    68641 ctttgtttta cactttatca taacacaaat agtgagaaag tggctacttg tggaggagaa
    68701 aaggctaaga aaacaaatca aaggctatca caatgacctg tgcgataaaa gtacttacag
    68761 aaacagtaat aaaagtttct ttaaaagcat ttttgtggtt aagtcctgtc aatgctaaga
    68821 aggtgagaaa gacaccactt tggggtacaa tggtaaagat attcgaagca atagtggcaa
    68881 cacggtgaat catttcggga ttaaggcctt gatctaaata atactgggca aaattaggca
    68941 tgacaattcc tagagcacct gaagaagaac cggtaatagc tgacatagag gaagtcaaca
    69001 cggctaaact aataagagga ttaccgggaa tattcaaaat gagatctgag aagaatgtga
    69061 aacctggggc aatcatcaca acggctccga aggcaactgc agatgctgtc gcaaaaatag
    69121 gtgcaataga gctgctagct cctaaattaa agacagcaat cttattagga ataaactgtc
    69181 taaagagcca gcttgcggtg agaatggcag ctaaaagtgc tatgaaaata atgttcttct
    69241 taaaaaaatc gtttccgaaa aggctaccgg ttagggcgat aataatgagc aacaataaag
    69301 gtaagatact ggcaaggaaa tgtgggagat tttttgtttt cacttgtatc tcattgtcaa
    69361 aagcataagt ggcataagtt tcaccccttg ccatactttt tgctagacaa tatttcatat
    69421 aaaagagccc aaaagtcacg cagccaattg agccaacgat actcggaatg gcggcagcag
    69481 ttagtgaggt gtccaagtat tgaataggaa taacattttg aatggcaggt gttccgggta
    69541 aaatcgtcat ggtaaaagtt gcaataccga gccaaagagg aacttgaatt aagttctaag
    69601 ccaagtccat ttttttgaat aggcttcgtg caagcggcaa gacagcaaac atgacaacaa
    69661 agaggctgat tcccccataa gttaatatag cactgatcag aaaaatagca acgagtactt
    69721 tataaggact atcatgacca acttttttta aaatataatc tgcaatagaa gtggttgcac
    69781 cgcttgtttc cattaatttg gctaagatag aacctaataa aaagatagca aaataattga
    69841 gaatataagt ggagagtgcc cccataaatt ggttgggttc ttttccaagt aaggttgtgg
    69901 ttggatccat ttgattaaac caaatgacca agctggtagc aagaggcgca gcgatgataa
    69961 tgttaacttc tttgacagac aggtaaataa taacaataac acctaccaag acccccagag
    70021 aaccaataat ttccatagtt ttatgacctc cttattagaa aataaagaga cagatcacaa
    70081 gatacagcct ctttatctct ccaaatttat tgagcagtgt agccaccgtc taagatacag
    70141 gcttgacctg taacaccttt tgccttatca ctggcaagga aagacacata gtctgcaatt
    70201 tcttgaacgt caatgaggcg tttttgagga acaagtgggt atagcacttc ttcaagaaca
    70261 ttttcaaggg gaatacctct tgttttggaa aggtcttcaa actggccacg aaccagtggt
    70321 gtgtcaacat atccaggaca aatggcattg accgtaatgc ctgaatcagc agcttctaag
    70381 gcagttactt tggtcagacc gatcaagccg tgcttagctg aattgtaggc ggatttgcca
    70441 gcaaaaccaa tgacaccatt gatagaagcc atattaataa tacgaccgtg tttttgagct
    70501 ttcattgtag gaaaagcacg tttaatggca ataaatggtg ctgtcaacat gattttaatc
    70561 atgaattcaa atttttcagt tggaaaatct tcaatcatgg caacatgttg aaggcctgcg
    70621 ttgttaacca aaatatcaat acgaccatat ttttcaacaa ccgtatcaat agcagcattg
    70681 atggctactt ctttggtgac atcgcacaca acactaaaag cgtcatagcc ttctttagta
    70741 tagtcagcaa caacctgatc cagtttttct tgattaatgt cagaaaaaac aaccgtttta
    70801 ccttctttta agaaggtaaa acggttgttt tccaattccg cttgcagcac cagtgataaa
    70861 tgcaacttct ttagtatgtg tcatgatact atcctcgtct ttcttttggt tagtctttag
    70921 tttgttttat caattagggt aacttcggta acgttttgca cgtcttcaaa ggtgtaatct
    70981 gggttaattt caagggcgca tagaccttca tcttgatatt caaagactcc catttcagta
    71041 atgattaggt taacaacatt ttgagcagtc agaggaaggg tgcatttgtc taaaattttt
    71101 gctttgcctt tattggtatg ctccattgca acaatgactt ttttagcacc taccaataag
    71161 tccatggccc ctcccatccc aggaaccatt tttccaggaa tcaggtaatt agcaatgcta
    71221 gcttctttat caacttgtaa ggcacctaag acggttgcgg ccacatggcc gcctcgaata
    71281 ataccaaagg aagttgagct atcgaagaaa gcccctccag gagcaatact aacaggttgc
    71341 ccaccagcat taacaatact aggatcgtag tgatcatctg ttaatccagt gagaccgaca
    71401 aaaccatttt cggactgcag ggtaatggtt acaccttcag gaatatagtt ggctactttt
    71461 gttggcaaac ctatgcctaa gttgaccagt gtattgtgtt ctaattcttg tgctacacgc
    71521 tttgcaatac gtgtttgaat ctcttctttt gaaagaacag tagctgatgt tcccatgtta
    71581 ggctcctttc actaagtagt taacaaaaat gccaggagta tggacaaaat taggatccat
    71641 ttgccccacg tcaacaactt ctcttgcttc aacaatggtg gttttcgcat tagcagccat
    71701 cacatgatta aagttatttt cagaacctgc gtattgcaaa ttgccatttt tatctgcctt
    71761 gttagcaaaa ataagtgcga tatcagcttt caaaggtttt tcaagaaggt agtctttgcc
    71821 gtcaatagta atgacttctt ttcctttggc aacttcggtt cctattccag taggtgttaa
    71881 gaaaccgcct agcccaaaac cgccactgcg gatgcgctca gctaatgttc cctgaggtac
    71941 aagatcaatt acagtctcgc cctcagtcat ttgtcggccc gcttcacggt tgagaccgat
    72001 atgtgatgca ataatagttg aaaactgttt attggcaacc atcttaccaa cgcctttgtc
    72061 aggaaaaccg gcatcgttac agattaaagt gaggtctttg acaccttttt ccacaagtgc
    72121 atcaattaat ttttctggtg tgccatttgt catgaagcca ccaaccataa tggtatcacc
    72181 atctttaacg tgagctaccg cttcttttat tgtgatttct ttacacattt tttctaccaa
    72241 ctttcacgag actaagtatt gtttttcacg ataacagcag ttccttgtcc tccaccaatg
    72301 caaagtgttg ctagtcctct ggttacttgg cgttttttca tttcgtggat taatgtgact
    72361 agaatgcgag cgccactggc accaatagga tgacctaaag cgatggctcc tccattaaca
    72421 ttcacgattt ctgggtttaa ctttaaatct tttaaaaccg ccaaggactg tgctgcaaat
    72481 gcttcattgg actccactaa gtccaaatca gaaattgtta atccagcttt cttaagggct
    72541 ttttgagtgg caggaattgg tccagttccc atcagttcag gtgcaacacc tgcactagca
    72601 tagctttcaa tagtgactaa aggtgttaac cctaattcaa gagctttttc ttcagtcatt
    72661 aacatcaata aggctgcacc atcgtttatt cctgaggcat tcccagcagt aacggttcct
    72721 tctttaggga ggaaagcagg acgtaattgc tgtaattttt caaggcttgt gtcaactttt
    72781 gggtattcat ccgtcgtaac aattaaagga tctttgcgtc gttgaggcac agagacaggg
    72841 acaatttcgt cagcaaaacg atgattttct aatgccctag cagctttttc ttggctttct
    72901 aaagcaaatt gatcttgctc ttctcttgag atgccatatt tctgagcaac gttttcagca
    72961 gtaataccca tgtggtaatt gttaaaagca tctgttaagc catcatgaac aagagtatca
    73021 atcaattgac tattaccaag acgttgacca aagcggtgct gagttgagac ataagctgct
    73081 tgtgacatgt tttcgacacc accagcaata acgatatcag cgtcaccaag catgatgctt
    73141 tgcgcagcta attggattgc tttaagtcca gaaccgcaaa ccatgtctaa tgtgaaagct
    73201 gttttatctt caggaattcc tgagtggact gcaacttgtc ttgccacatt ttgtcctagg
    73261 cctgcatgaa ggacgtttcc taggatgact tcatcaacca tttcaggctt tacttgcgtt
    73321 ttatcaagga tttttttcag tacagttgtt ccaagttcaa cagcagagac acttttaaag
    73381 gagcctccaa aagctccgat aggagttcgt aaagcttcaa cgataactat atttttcata
    73441 aaataaacat cctttcagtt ttagaaagcg ctttccatgt ctctaagata acaagaaaac
    73501 gctaaaaata aaaatataga atttttataa gcgtataaat ttttttgata gagttggcaa
    73561 tagcatttaa catctacttg tgtcataata taggtaatta taccggaaaa agcaattgat
    73621 aagacaagga gaatcctatt tggatattaa acaaattcgt tattttatcg ccatcgttga
    73681 aaatcatttt aacttgagcc aggcggcgga actgttgtat gtgtcgcagc cgacacttag
    73741 catgatgatc aatgattttg aaaaaaggga aaatgttaag ctcttcaaac gaaaaagagg
    73801 tcgtattatt gggttaacct atcttggtga taattattat aaggacgctc aaaaggttct
    73861 cagtctctat gatgacatgt ttttgaaatt gcatgatcac agtaaagggt taaagggaag
    73921 tatcaatatt ggtattcctc ctcttatttt atcagttgtt ttctcagaag taatgtcaaa
    73981 actgatttta gaaaatccgg ggattcaatt caatgttaag gagattggtg cttaccaact
    74041 aaaaaatgaa ctactcgtgg gaaatgttga cgtcgcagtc ttgttatccc caacaggcat
    74101 cgctgataat ttggttgaga cttatgaaat ccagagatca gaattatctg tatgcctgtc
    74161 tccacgccat cggttagctt ccaaaaaagt tattcagtgg aaagatttaa cagatgaaca
    74221 acttgcccta tttgatccta gtttcatggt tcaccattta gtgcttgaag cttgcgagcg
    74281 tcaccaagtc agacctaata ttattttgac gtcctcttcc tgggatttta tgcttaattc
    74341 taccaagatt aatcacaacg tcttaactat ttgtcccaaa cctattacag aattatacca
    74401 attaaaggac attaagtgta ttccaatgga acgtcccatt tcttggcgtg ttgtcttaac
    74461 acgcctccgg aaaaaaagtt attctgaaat agaagcctac atcatggacg acttgctaca
    74521 gtcttttttt aagtaggatt ctcaaccact tggcccagat gttaattttt ttaaaaatga
    74581 attggaattg tgtaaacgct caatttatga taaactaaga ggtggctttc tattaatgaa
    74641 atctagaata tattgaggta caaacatggt taatattatt ttattaattg tttctgccct
    74701 cattggttta atattaggtt atgcacttat ttcgattaga ctcaagtctg cgaaggaagc
    74761 tgcagagttg actcttttaa acgctgaaca agaagctgtt gatattcgtg gcaaagcaga
    74821 agtagatgct gaacacatca aaaaaacagc taaacgtgaa agtaaagcaa atcgtaaaga
    74881 attactttta gaagcaaaag aagaggcaag aaaatatcgt gaagagattg aacaagaatt
    74941 taagtctgaa agacaagagc ttaaacaact cgagacacgc ttagcggagc gctccttaac
    75001 tcttgaccgt aaagatgaaa acctatcaag taaagaaaag gtactagata gtaaagaaca
    75061 aagtctgacc gataaatcta aacacattga tgagcggcaa cttcaagtgg aaaaacttga
    75121 agaggagaaa aaagcagaac tggaaaaagt tgctgcgatg acgattgcag aagcgcgtga
    75181 agtgatttta atggagacgg aaaacaaact gacccatgaa attgcgacgc gcattcgaga
    75241 tgccgaacgt gacatcaagg accgaacagt taaaacagcc aaggacttgt tagcgcaagc
    75301 catgcaacgc cttgctggtg agtatgtgac tgaacaaact attaccagtg tccatctccc
    75361 agacgacaac atgaagggcc gaattattgg acgtgaaggc cgtaatattc gtactttaga
    75421 gagcttgact ggcattgacg ttattattga cgatactcct gaagttgtta tcttgtcagg
    75481 atttgatcct attcgacgtg aaattgctcg tatgaccttg gaatctctga ttgctgatgg
    75541 tcgcatccat ccagctcgta tcgaggaatt ggttgagaaa aatcgtcttg aaatggataa
    75601 tcgtattcgt gagtacggtg aagctgcagc ctatgagatt ggtgcaccaa accttcatcc
    75661 tgatttgatt aaaatcatgg gacgcctgca attccgtacc tcgtttggtc aaaatgtcct
    75721 acgtcactct gttgaggttg gtaagttagc tggtatttta gctggtgagt taggtgaaaa
    75781 tgttgctctt gcccgccgtg ctggtttctt gcatgatatg ggtaaagcta ttgaccgtga
    75841 ggttgaaggt agtcacgttg agattggaat ggaatttgca cgtaaataca aagaacatcc
    75901 agttgttgtc aacactattg ctagccacca cggagatgtg gagccagatt ctgtgatcgc
    75961 tgtgctagta gctgcagcag acgctctcag ttcggctcgc ccaggcgctc gtaatgagtc
    76021 aatggagaat tacatcaagc gtcttcgtga tttagaagaa atcgcgacaa gttttgatgg
    76081 ggtacaaaat agttttgctc tacaagctgg acgtgagatt cgtattatgg ttcaacctga
    76141 aaaaatttca gatgatcagg ttgtcatttt gtcgcataaa gtaagagaaa aaattgaaaa
    76201 caatctagat tacccaggaa atattaaagt aactgttatt cgtgagatga gagcggttga
    76261 ttatgccaag tagaaaaaga ggaattatcc tctttttctt tatgacttgc ctttgaaaat
    76321 gttcttgaaa aagactagcc tttttgataa actattaaaa agcaactaat aaggagaata
    76381 caatgtctga acgcggtttg ttaatcgtct tttctggccc ttcaggtgtc ggaaaaggaa
    76441 cggtaagaca agaaattttt tcaacgccag atcataaatt tgaatattcg gtttcaatga
    76501 cgactcgtcc gcaaagaccg ggcgaggttg atggggttga ttatttcttc cgcacacgtg
    76561 aagaatttga agaactcatt aaaactggtc aaatgctaga gtatgctgaa tatgttggta
    76621 attactatgg aaccccttta acttatgtta atgagactct tgataaggga attgatgtct
    76681 ttttagaaat tgaagttcaa ggagctcttc aggttaagtc aaaagtacca gatggtgttt
    76741 ttgttttttt aacaccacca gatttagatg aattagaaga ccgcctggtt ggtcgtggta
    76801 cagatagtca agaagtcata gctcaacgta ttgaaagagc aaaagaagaa attgccctta
    76861 tgcgcgaata cgattatgca gttgttaatg atgaagttgc cttggcagct gagcgggtta
    76921 agcgtatcat tgagacagaa cactttcgtg tggagcgcgt gattggtcgt tatgataaaa
    76981 tgattaaaat aacaaaaaat ccctttaaag ctaaatagaa aagagtaagc attatgatgt
    77041 taaaaccttc cattgatacc ttattagata aagtaccatc taagtattca cttgtgattt
    77101 tacaagccaa acgtgcccat gaactagaag ctggtgccac tccaactcaa gaatttaaat
    77161 cagtgaagtc aacacttcag gcacttgaag aaattgaatc aggaaacgtt gtgattcacc
    77221 cagatccttc agctaaacgt gaagctgtcc gtgctaagat tgaggcagaa cgcttggcca
    77281 aagaggaaga ggaacgtaaa atcaaagaac aaattgccaa agaaaaagaa gaagaaggag
    77341 aaaaaatcta aggtttcagg aatcttagat tttttcatat ttagtacgat gtccatgaca
    77401 gaaaaggaga agcaaatgga aaaagtagct catgtgattg tagatattcc attgatgcaa
    77461 acggacaagc cattttctta tggtattcca aaagagttag tttctctcgt gcagcttggt
    77521 tctcgtgtgc atgttccttt tggaaaaggg aatcgtttgt tgcaaggctt tgttattggt
    77581 tttggccagg aagattcaag ctctcttaaa ctgattcaga ccgttttaga tcctgagcca
    77641 gtcctaaacc aagaacaatt gacccttgct gatcagcttc gaaaaacagt tttttcttat
    77701 aaaatcacgc tcttaaaagc aatgattcct aatcttctta actctaacta tgataaagtg
    77761 ctaaggccag agtcaggtct aaaaaagcct gatagagact ttctttttga aggaaaacca
    77821 tctgtcttat attctacctt agaccgcgag aaggaaaaaa tagctcttaa ggccatacaa
    77881 gctgggcata ttactgttag ttatttagcc aaagacaaga aaaacctaaa gacagaaaaa
    77941 tattatcacg tcgacttaga cgccttagcg gtacatccca tctctagtcg tgccaaaaag
    78001 cgtcaattat taaaagacta tctgctaacc catacgaagg aagctaaact tgcaacgctt
    78061 tatcaagcct tttctcgaga tgtggtggct tactttgtga caaatcactt aattcgtatt
    78121 gacgaacgtc aaattgatcg cagtgagccc tattttgacc agatcaaacc atcttctttt
    78181 ttaaccttaa atgaacagca agcgtcagct gttactgaaa ttgttgagca aattgggaaa
    78241 ccgagtaaac cttttttgat tgaagggatt acaggttcgg gtaagacaga agtttatctt
    78301 catatcatcg aagcagtttt aaaacaggat aagacagcca ttgttttagt accagaaatt
    78361 tcgttgactc ctcagatgac ctctcgtttt atttcccgtt tcggaaagca agtggctatt
    78421 atgcattcag gcttatcaga tggtgaaaag tttgatgagt ggcgcaagat aaaaacagga
    78481 caggctaagg ttgtggttgg tgcccgctct gctattttct ccccactaga gcggattggt
    78541 gcaattatta ttgatgagga gcatgaatca acctataaac aagaaagcaa ccctagatac
    78601 catgccagag aggttgccct gctcagagct aaacaccatc aagcagttgt ggttatgggc
    78661 tctgctacgc caagtattga aagccgagca agggctagta agggggtcta tcattttatt
    78721 caattaacgc aaagagcaaa tcctcttgct aagattccag aagtaacgat tgttgatttt
    78781 cgtgattata ttggacagca agcagttagc aattttaccc catatttgat tgataagatt
    78841 aaagaacgtt tggttaaaaa agaacaagtt gtcttaatgt taaatagacg tggttattct
    78901 agttttgtga tgtgtcggga ctgtggttat gtggacaaat gtcccaactg tgatatctcc
    78961 ttaacccttc acatggatac taaaactatg aattgccatt actgtgggtt tcaaaaacct
    79021 atcccaatta cttgtcctga gtgtcatagc aacagtatcc gctattatgg cactggaact
    79081 caaaaagctt ttgatgaatt gcaaggggtt atcccagaag ctaggatctt gagaatggat
    79141 gttgacacca cacgaaaaaa aagaagtcac aaaaccatac tagatagttt tggtcgccag
    79201 gaagcagata ttttgttagg gacgcaaatg attgccaaag gactggattt tccaaatgtg
    79261 actttagttg gggtactaaa tgcagatacc tccttaaatt tgccagattt tcgagcgtca
    79321 gaaaaaacgt ttcaattgtt aacacaggtt gctggtcggg caggccgtgc ccataagcca
    79381 ggagaagtct tgattcaaac ttataatccc gatcactatg ctattcaatt agctaagaaa
    79441 caagattttg aagcctttta ccgttatgaa atggcgattc gccgtcagat ggcttatccc
    79501 ccttactact ttacagtggg tattacgctt tcgcatcgtt tagaagcatc ggttgtaaaa
    79561 aaagcttatc aagttacaga actgctaaag agtcacttat cggataatat taaaatatta
    79621 ggaccgactc ctaagccaat tgctagaaca cacaatttat accactatca aattttgtta
    79681 aaataccgtt ttgaagataa cctagaagag acgctcaatc gtattcttga ttggagtcaa
    79741 gaagcagata atcgtcattt aaaactaatt attgattgtg aaccgcaaca atttttataa
    79801 ggtaaatcac taaatctagg atgatcagtt atgatataat aaaaatacaa agaggaaagt
    79861 catgataaaa ttattattta tgggaactcc ccaattttca gcaactgtat tgaagggctt
    79921 gctagataat cctgcctatg agattttagg agtggttact cagcctgatc gagctgttgg
    79981 acgcaaaaaa gatattaagg taacacctgt aaagcaatta gctcttgagc atggaatatc
    80041 aatctatcag ccggaaaaat tatcaggctc tcaagaactc attgagatta tgggacttgg
    80101 tgcagatggt attattacag cagcatttgg ccaattttta ccaacactat tacttgattc
    80161 agtttcattt gctattaatg tacatgcatc attgttacct aaatatcgag gtggagcacc
    80221 tatccattat gctattatga atggagataa agaggctggc gttactatta tggaaatgat
    80281 taaagaaatg gatgcaggtg acatggtcgc taaagcaagc actccaattc ttgaaaccga
    80341 taatgtaggt actctttttg agaaattagc catcattggt cgagacttac ttttggatag
    80401 tttgccagct tatctttctg gagaattaaa acctattcct caagatcaca gccaagctac
    80461 tttttcacct aatatctctc cagaacaaga aaaattagat tggacaatgt ctaatcaaga
    80521 agtgttcaat catattcgtg gtatgaaccc ttggccggta gcgcatacgt ttttagaggg
    80581 gcaacgttta aaaatttacg aagctcaact agctgaagga gaaggattac ctggacaagt
    80641 tattgtcaaa accaaaaaat ctttggtaat agctactgga caaggagctt tgtccttgat
    80701 cgttgtgcaa ccggctggta aacctaaaat gtcaataata gactttttaa acggcattgg
    80761 tagaaaactt gaagtagggg acatcattgg cagataattg gaaaaaaagt acgcgaggca
    80821 aagccctcct tgtcattgaa gctatttttg atcagggagc ttacacaaac atagcgctta
    80881 atcagcagct aagcaataaa gctttatctg ctaaggacag agctctatta actgagattg
    80941 tatatggtac cgtttcacgt aaaattagct tggaatggta tttagcccat tatgtcaaag
    81001 accgagataa attggacaaa tgggtttatt atctccttat gctcagtctt tatcaactga
    81061 cttatttaga taagttacca gcgcatgcca ttgttaacga tgcggttggt attgccaaaa
    81121 atcgtggcaa taaaaaaggt gcagagaagt ttgtcaatgc tattttacgt caattcacca
    81181 gccatcctct cccagatatg gaaacaatta agcgtcgaaa taagtattat tcggtcaagt
    81241 attcactgcc tgtttggttg gttaaaaagt tagaagacca atttggctcc cacagagcag
    81301 tggctattat ggagagttta tttgtgcgta gtaaggctag tattcgcgtg acggaccctt
    81361 tgaagttaga agaagttgct gaggctttag atgcagaacg ttccctttta tcagcaactg
    81421 gtttaaccaa agcgtcaggt cattttgcag ccagtgatta tttcacaaat ggggacatca
    81481 ctattcaaga tgaaagcagt cagcttgtag ctcctacttt aaacattgac ggtgacgaca
    81541 taattcttga tgcgtgtagc gctccagggg gtaagacctc tcatatagca tcttacttaa
    81601 aaacaggtaa agttattgcc ttagatctct atgatcataa actagagttg gtgaaggaaa
    81661 atgctaaccg cttaggagtt gctgataaca ttgagacaag aaaactagat gccagagagg
    81721 ttcatcgtca ttttgaaaag gatagctttg ataagatttt ggtggatgct ccttgttcag
    81781 gaattggttt gattcgtcga aaacccgata tcaaatataa taaagaaagt caagatttta
    81841 atgctctaca ggctatccag ctagagatat tgtctagtgt ttgtcaaacc ttgcgtaaag
    81901 gtggtataat aacatacagt acttgcacta tttttgatga ggagaatcgt caagtcatcg
    81961 aagcattttt acagagtcat cctaattttg aacaagtaaa actgaaccat acacaagcag
    82021 atattgtcaa ggatggttat cttattatca caccagaaca ataccagact gatggcttct
    82081 ttattggaca agtcagacga gtcttgtagt attttaggag gaaactgact gagtcagaaa
    82141 aaacgtatga agatttcatt aaaaacagac attgggcaaa aacgctcaaa caatcaagat
    82201 tttatcaata agtttgataa taaaaaaggc atcactttag tgattttagc agacggtatg
    82261 ggtggccaca gagctggaaa tattgccagt gagatgacag tcacagacct gggaagagaa
    82321 tgggtaaaaa cagacttcac agagttaagt cagattagag attggttatt tgaaactatc
    82381 cagtcagaaa atcaacggat ttatgatcta ggccaatcag aagactttaa aggaatggga
    82441 acgactgttg aagcagtagc tttagttgaa tctagcgcca tttatgctca tattggtgat
    82501 tcacggattg gtcttgtcca tgatgggcat tataccttat tgaccagtga tcattcttta
    82561 gtgaatgagt tggttaaggc aggacagatc acagaagaag aagctgctag ccatccacaa
    82621 agaaatatta tcactcaatc tattggtcaa gcttccccag tagagcctga tttaggagtg
    82681 agagttttgg agccagggga ttatcttgtc attaacagtg atggtctaac caatatgatt
    82741 tcaaatgatg aaattgtgac tatcttgggc agtaaggtta gtcttgatga aaaaaaccaa
    82801 gaaatgattg acttagctaa cctaagagga ggcctagata atattacaat cgctttggtt
    82861 cacaacgaaa gtgaggacgt cgaatgattc agattggcaa attatttgct ggtcgttatc
    82921 gcattctgaa atctattggc cgcggtggta tggcggatgt ttatttagca aatgatttga
    82981 tcttggataa tgaagacgtt gcaatcaagg tcttgcgtac caattatcaa acagatcagg
    83041 tagcagttgc gcgtttccaa cgagaagcgc gggccatggc tgaattgaac catcccaata
    83101 ttgttgccat ccgggatata ggtgaagaag acggacagca atttttagta atggaatatg
    83161 tggatggtgc tgacctaaag agatacattc aaaatcatgc tccattatct aataatgaag
    83221 tggttagaat tatggaagaa gtcctttctg ctatgacttt agcccaccaa aaaggaattg
    83281 tacacagaga tttaaaacct caaaatatcc tactaactaa ggagggtgtt gtcaaagtaa
    83341 ctgatttcgg catcgcagta gcctttgcag aaacaagctt gacacaaact aattcgatgt
    83401 taggcagtgt tcattacttg tctccagaac aggctcgcgg ctccaaagcg acgattcaaa
    83461 gtgatattta tgcgatgggg attatgctct ttgagatgtt gacaggccat atcccttatg
    83521 atggcgatag tgctgttacg attgccttgc aacattttca aaagcctctt ccatctatta
    83581 tcgaggagaa ccacaatgtg ccacaagctt tggagaatgt tgttattcga gcaacagcca
    83641 agaaattaag cgatcgttac gggtcaacct ttgaaatgag tcgtgactta atgacggcgc
    83701 ttagttataa tcgtagtcgg gagcgtaaga ttatctttga ggatgttgaa agtaccaaac
    83761 ccctccccaa agtggcctca ggtcccaccg cttctgtaaa attgtctccc cctaccccaa
    83821 cagtgttaac acaggaaagt cgattagatc aaactaatca aacagatgct ttacagcccc
    83881 ccaccaaaaa gaaaaaaagt ggtcgttttt taggtacttt attcaaaatt cttttttctt
    83941 tctttattgt aggtgtagca ctctttactt atcttatact aactaaacca acttctgtga
    84001 aagttcctaa tgtagcaggc actagtctta aagttgccaa acaagaactg tatgatgttg
    84061 ggctaaaagt gggtaaaatc aggcaaattg agagtgatac ggttgctgag ggaaatgtag
    84121 ttagaacaga tcctaaagca ggaacagcta agaggcaagg ctcaagcatt acgctttatg
    84181 tgtcaattgg aaacaaaggt tttgacatgg aaaactacaa aggactagat tatcaagaag
    84241 ctatgaatag tttgatagaa acttatggtg ttccaaaatc aaaaatcaaa attgagcgca
    84301 ttgtaactaa tgaatatcct gaaaatacag tcatcagtca atcgccaagt gcgggtgata
    84361 aatttaatcc aaacggaaag tctaaaatta cgctcagtgt tgctgttagt gatacgatca
    84421 ctatgcctat ggtaacagaa tatagttatg cagatgcagt caatacctta acagctttag
    84481 gtatagatgc atctagaata aaagcttatg tgccaagctc tagctcagca acgggctttg
    84541 tgccaattca ttctcctagt tctaaagcta ttgtcagtgg tcaatctcct tactatggaa
    84601 cgtctttgag tctgtctgat aaaggagaga ttagtcttta cctttatcca gaagtaacac
    84661 actcttctag tagctcatcg agttcaacgt caagttcaaa cagttcttca acaaatgata
    84721 gtactgcacc aggtagcaac actgaattaa gcccatcaga aactactgct caaacacctt
    84781 aacaaagaat agttagtctc atgttttact agcatgccac taactattct ttttaactac
    84841 tcgtcatata aagatgcaat tttccaggaa ttctgataaa atacaaagaa ataaggggaa
    84901 actaatgaaa aaatttcaat tctttttact tatcgagtgt atactgctag ctatgggtat
    84961 catgacaatc ttggataatg atttatcaag ttttatccta attctagttc ttatcttatt
    85021 agcattacgc ttttataacc aagatagccg caataatttt ttactaactg tcagtttatt
    85081 gtttcttttt ttaattttca tgcttaatcc ctacattatc atggctgttc ttttggggat
    85141 agtttacatt ttcattaacc atttttcaca agtcaaaaag aagaatcgct ttgccttgat
    85201 tcgtttcaag gaagaaaaga ttgaagtgaa caataccaag catcaatgga ttggtactgc
    85261 taattatgaa agtgattatt attgttttga tgacattaac atcattcgaa tctcaggaaa
    85321 tgacacggtt gacttaacca atgttattgt gacaggaatg gataatatca ttgtgatacg
    85381 taaaattttt ggaaatacga ctatattggt acctattgat atcactgtta ctttagatgt
    85441 tagttccata tacggaagcg ttgatttttt tagatgtcag caatatgatt tgcgcaacga
    85501 atctattaag ttaaaagaaa cggataacca atcccttaaa aaagtcaaaa ttatcgttac
    85561 aactattgcc ggaaatgttg aggtggatag gcgatgaaaa aacgttacta tgctcttgtt
    85621 tggctctact caaccattac cattttatct attgtttttg tggtcatgga taatttagga
    85681 atcactttta actaccttcg caatcattta tggcaggtcg aacgtctagg gttttcgatt
    85741 ttattgttga ttgtttctgt gactttatta ttgttgttat tgtggattat tatggatgat
    85801 aacagtaagc gtaacatcaa ccaaaatcta aaatatattc tcaataatcg acgactctat
    85861 ctagatgaga catcagaaat caatactaat ttaagtcgac tttctaaaaa aatgtctcac
    85921 ctgactgcta acatgcaaaa gaaagaaagt gcttatattc ttgatagcca agaagttgta
    85981 aaacaagagc gcaaacgaat tgcaagagat ttacatgaca cagtcagtca agagctattc
    86041 gcttcgtcat tgattttatc aggaatttcg atgagtttgg aacaactgga caaaacacaa
    86101 ttacaaacac agttaacaac ggttgaagca atgttgcaaa atgctcaaaa tgatctacgc
    86161 attctccttt tgcatcttag acctaccgag ctagctaatc ggactttatc tgagggcctt
    86221 aatatgattc ttaaggaatt aacagataaa agtgatattg aagtcattta taaggaaacc
    86281 attgctcagc ttcctaaaac aatggaagat aatcttttta gaattgccca agaattcatt
    86341 agcaacacgt taaaacatgc taaagctagt cgaattgaag tttatctcaa tcaaacctca
    86401 acagaattac aattgaagat gattgatgat ggtgtaggat ttgatatgga tcaggtaagg
    86461 gatttgagtt atggtctgaa gaatattgaa gaccgtgtca atgatttagc aggaaaccta
    86521 catttaatta gtcaaaaagg caaaggagtt tccatggata ttagactgcc gatagtgaag
    86581 ggagatgacg atgagtaaga taaaagtgat attggtcgat gatcatgaaa tggtccgcat
    86641 gggactcaag agttttttga atttacaagc tgatattgat gtcgttggtg aagcctctaa
    86701 tggacgtgaa ggggttgatt tggcattggc cttgaagcca gatgttttgg ttatggatct
    86761 agtgatgcca gagttaggcg gtgttgaggc aactttagaa gtcctaaaaa aatggaaaga
    86821 ggctaaggta cttgtgttaa cttcctatct agataatgaa aagatatacc ctgtcattga
    86881 tgctggtgct aaaggttaca tgttaaagac ttctagtgca gccgaaattc taaatgctat
    86941 tcggaaagtt tcaaaaggtg aattggccat tgaaacagag gtggacaaaa aaattaaagc
    87001 gcatgaccaa caccctgatt tgcatgaaga gctaaccgcg cgcgagtatg atattttaca
    87061 tcttttagct aaagggtatg ataatcaaac tatagcggat gaacttttca tctccttgaa
    87121 aaccgttaaa acgcatgtat ctaatattct tgctaagcta gaagttgatg accgaactca
    87181 agcggttgtc tatgcttttc gacaccattt agtcccccaa gacgataatt aatgctataa
    87241 tatagggtat agcaaattgg aggaaagtat ggacgcaaaa ctaaaataca aagctaaaaa
    87301 aatcaaaatg gtgttctttg atattgatga taccttgagg gtcaaagata cgggttatat
    87361 gcctgagtcg attcaaagag tatttaaggc tttgaaggca aaaggcatct tggttggtat
    87421 tgcttcaggt cgcgctcggt acggtgttcc acaagaagtt caagatttac atgctgacta
    87481 ttgtgtcaaa ttaaatggag cttatgtcaa agacgatgct aaaactatta ttttccaagc
    87541 tccgattcca gcagatgttg ttgtggccta taaaaaatgg gcggatgata tgggcatttt
    87601 ttatggaatg gcgggtcgtc atgaagcggt gttgtccgct cgaaatgaca tgattagcaa
    87661 tgctattgat aatgtctacg ctcaactaga ggtctgtccg gattataatg agtatcatga
    87721 tgtttaccaa atgtggacct tcgaggacaa gggagatggc ttgcagttgc ctgctgaatt
    87781 agcagagcac cttcgtttgg tcagatggca cgataactca tcagatgttg tcttgaaagg
    87841 tacgtcaaaa gcgctaggtg tttcaaaagt agttgaccat ttaggattaa aacctgaaaa
    87901 cattttggtg tttggtgatg aactaaacga cttagagtta tttgactatg ctggtatcag
    87961 tattgcaatg ggagtatcac acccacgttt gcaagaaaaa gcagatgtta tcacaaaaaa
    88021 agttgaagaa gatggcattt tatatgcctt ggaggaatta ggattgattg acaaagaatt
    88081 acagtttcca caattggatt tagaaaatca tactggacca aaagtaacca ttaaaacaaa
    88141 tcatggggat atgactttgg tcttgttccc agagcattcc cctaagacgg ttgctaactt
    88201 cttaggatta gctaaagagg gatactatga tggcattatt ttccaccgcg ttattcctga
    88261 atttatgatt caaggtggtg atccaacagg aacaggaatg ggtggacaat ccatctatgg
    88321 tgaaagtttt gaagatgaat tttcggatga actgtataac cttagaggag ccctttcaat
    88381 ggcaaacgca ggcccaaata ctaatggtag ccaattcttc attgttcaaa atagcaaaat
    88441 tccttacgct aaaaaagaat tagaacgtgg tggttggcct actccaattg cagctgctta
    88501 tgctgaaaat ggtggaactc ctcaccttga tcggcgtcat actgtttttg gccaattagc
    88561 tgatgacgct tctttcaaag ttttggacct gattgctagc gttgaaactg gcgcacagga
    88621 taaacctaaa gaagacgtta tcattgaaac aattgaggta tttgactaat gaaaattggc
    88681 gacaaactgc atggcaccat cactgggatt aaaccatacg gagcctttgt tgcccttgac
    88741 aatgggacaa caggtctcat tcatatttca gaaataaaaa cgggatttat tgatgatatt
    88801 gatcaattat tggctatagg caaccaggtt ttagtacaag taattgatat tgatgaatat
    88861 agtaaaaagg caagtttatc tatgcggacc ttagcagaag aaaaacagca ttttttccat
    88921 cgtcatcgtt attccaacag tcggcacaag attggcttta ggccacttga agagcagtta
    88981 cctcagtgga ttgaagaaag cctgcagttt ttaaaaaaga acactaaaaa gagtctggaa
    89041 ccttagtagt tccaaaccct tttttatttc gtcttaatta ctggtacatc atagagttca
    89101 gtcgataaat agcgttcgcc attatctggt aaaatagtta acacatgttt gccttttcct
    89161 aactgtttag cgacttcaat agcggcgtaa agagcagctc cagaagaaat cccaaccagg
    89221 aagccttcct tagctcctgt tagtcgagca gtttctaaag catctttcga tttaacacgg
    89281 ataatttggt cataggcttt ggtatctaac gtgtttggga taaatccagc tgatatacct
    89341 tgaattttat gtggtccagg ctcttgacca gataagacag cagattcctc agcttcaaca
    89401 gcatagatag cagtttcagg gttagctttt ttcaagacat gtgaaacacc agaaagtgtt
    89461 cctccagtac caacaccaga tacgaatgca tctaaagaaa tctccttaaa agcttccaaa
    89521 atttcttgag ctgttgtttt ttcatggatg cttggattgg cagggttatt aaattgcata
    89581 ggcatccaag cacctagttc tattgctaaa gtttcagctt ttgcaatagc ccctttcata
    89641 ccttctgctc caggtgttaa gacaagctct gcaccataag cctgaatgat ttgtcgtctt
    89701 tccaagctca tagtttcggg cataacaata atgactcgat accctttagc agcacctacc
    89761 catgcaagac caatacctgt attaccgctt gttggttcga taataacgtc accaggactt
    89821 atcagacctt cagcttcagc agcttcaatc atcgataaag caatacgatc tttaacagaa
    89881 gatcctgggt taaaagcttc taattttaca taaacgtcag cagcttcgtt tggaattaaa
    89941 cagttaagtt tgataatagg tgtttgacct actaattctg ttatagtttt gtaaatttta
    90001 gtcatagttt agcctctttt cttgatacaa aataaatacg ctgtgtattt aagtataagg
    90061 agagatatta ttaaagtaaa atacagattt actatcactc tgataataaa gccatatcac
    90121 ttttgttgat gattaatcac aggggaattc aataactttg gatccgattt tctcacagct
    90181 tatctgacca tgataataat ttgttaaagt atcaatgaga ttttccacac gttcagtatc
    90241 acaataaagt gttgtcttta tcgtgtctga aaacttagtt tctgtttcgg ttaaagccaa
    90301 ttgatctagc aagttagagt atagttggta ttggggataa gaaagtgtga tttctagtcc
    90361 tatctgctgt ttaacttcaa tgatgccaaa tcgtttaata gctgttgcgg tcatgttaga
    90421 gtatgctctg attaacccac ctgttcctaa tttaatacca ccaaagtaac gcgttaccac
    90481 aactactaca tttgttaaac actgtttttc taacacagaa aggataggta ttccagcagt
    90541 tcctgaaggt tcaccatcat cacttgagcg cttgatctga ctgttgttac cgataatcat
    90601 cgcaaagcag gaatgattag ctttgtaatg ttcttttttg atagcattaa caaaattctt
    90661 accatcttct tcagtgctca ctcgtttgat atgacaaatg aaacgagatt ttttaatact
    90721 ttcttcgaaa aaaccactgg ctttgattgt cttaaaatgt tccataaaaa aattgtacaa
    90781 gaaaagataa aaattagcaa aaaaagcgaa taataaagta tggagtctat tgaaaatagt
    90841 tatgggcggt tgttgctaga aaaccagtta ccagattcag caaggcagct tgctcaacct
    90901 ttaaaaagtg tagtaatatc gagaggaaaa atgatttgtc aacgttgtca ctatcagctt
    90961 gatgaagaag cacgattgcc aagtggagcc tattattgcc gattttgtct tgtctttgga
    91021 cgaaatcaat caaataaatt gctctatgct atcccaccta tgcattttcc aaaaggtaat
    91081 tatctggttt ggagcggtca actaactgct tatcaagaga tgatttccca acaattatta
    91141 atcaatatgc aaaatcaaaa aacaacatta gttcatgctg taactggtgc aggaaaaaca
    91201 gaaatgattt atgctgcgat tgaggcggta attaacacag gtggctgggt ttgcattgcc
    91261 agcccaagag tagatgtttg tgtagaggtg gctactcgtt tatcccaagc cttctcctgc
    91321 agcatctgtt taatgcacgc agagtctctt ccttatcaaa gagctcctat tatagtagcc
    91381 acaacgcatc agctgctaaa atttcacaag gcttttgatc tcttaattat tgatgaagta
    91441 gacgcattcc cttttgtaaa taatattcaa cttcattatg ctgcaagtca ggctttaaaa
    91501 gaaggtggcg caaagatttt attaactgca acttcaacta gaactttaga aagaaaggta
    91561 aacaagggag aagtagtcaa gctgacattg gcaagacgct ttcataatag gccattagtt
    91621 attccgaaat ttataagaag ttttaatcta tttaaaatga tacatcggca aaaacttcct
    91681 cctaaaattt taaaatactt aaaaaaacaa agaaaaacag gctatcccct tttaattttt
    91741 ctacccacta ttataatggc agaatctgtt acagcaatct taaaagagtt attgcccgcc
    91801 gaacaaatag cttgtgtttc tagtcaatca caaaacagga aagaagatat cacagctttt
    91861 cgtcaaggga aaaaaacgat tttaattaca acaacaattt tagaaagggg tgtgacattt
    91921 ccccaaattg atgtttttgt tcttgggtct catcatcgtg tctatagttc ccaaagtctt
    91981 gttcaaattg ctggacgagt tggaagatct atagacagac cagacggaac gttatatttc
    92041 tttcatgaag gtatcagtaa agcaatgcta ctagcaagaa aagagattaa agaaatgaat
    92101 tataaagggt attcgcatga tctgtctact atgtcaacaa attagtcaaa caccaataag
    92161 tattacagaa atcatctttt taaggcgtat ctcttcaccg atttgtcaac aatgtcaaaa
    92221 aagctttcaa aagataggaa aaagtgtttg tgcgacatgt tgtgcaaact cagatataat
    92281 agcttgtcga gattgtctaa aatgggaaaa caaaggatac aatgtaaatc atagaagctt
    92341 atattgttat aatgctgcta tgaaagcata cttcagtcaa tataagtttc aaggagacta
    92401 tttattaaga aaagtttttg cagtagaact tgccgatgtt attaccaagt actataaagg
    92461 ctatatccca gtcccggttc ctgtaagtcc cggttgtttt cgagaaagac aatttaatca
    92521 agtgagcgct attcttgatg cagctaatgt tagctacctt tctctttttg aaaagctaga
    92581 taatactcac caatcttcca gaacaaaaaa agagagatta ttagtagaaa aatcttatcg
    92641 actactaaaa gtatcaaaca ttcctgataa aatccttata gtagatgata tttatactac
    92701 tggtagtaca attatcgctc ttagaaaaca attggctaaa gtagcaaata gtgacattaa
    92761 aagtttgtca attgcacgtt aaaacttgca aattttcatg aaagcagtat aatagtatta
    92821 aagataaagt aagcgcttca agcgcgagaa agaggtatcc tatgattaag ttcagtattc
    92881 gtggagaaaa tatcgaagtg acagaagcta ttcgcgatta tgtagaatca aagcttacta
    92941 aaatcgaaaa atattttgct aaagaccaag aaatagatgc acgtgttaat ttaaaagttt
    93001 atcgggagag atcttcaaaa gttgaggtaa cgatcccatt agattcagta acccttcgtg
    93061 ctgaagatgt ttcacaggat atgtacggct ctattgattt agttgttgat aagatcgaac
    93121 gccaaattag aaaaaataaa accaaaattg ctaaaaaaca tcgcgaaaag gttccaactg
    93181 gtcaagtctt tacaactgag tttgaagctg aagaagtcga tgagatacca gaagtacaag
    93241 ttgtacgtac taaaaatgtg acattaaaac caatggatgt tgaagaagcg cgtttacaga
    93301 tggaactatt gggacatgat ttctttatct acactgattc tgaagatggt gcaacaaaca
    93361 ttttataccg tcgcgaagat ggaaacctag gattaataga agctaaatag ttcacaacta
    93421 aaacctacag ggatgattat acgtatttta aaagtgggaa aaagctattc atgtttcgag
    93481 gtgacatgat gaaaatgaga ttaagtgata gatacgacag tcattatata acaaaagtat
    93541 ctattacagt tcctctttaa gtaaatctta cgtaaaatta gtttgaaaaa aagattagtc
    93601 ccaattctgg gctagaaatt ctcaaaaaat atgaaaaagc gcgttttcag aatataaagc
    93661 gcgttttttt ctttttccat ttaacaataa aaaactcatg acgaacatgg tatcataaga
    93721 gaatttttac tttttaaaaa aaggtcaaag actttctgac accaaataaa aatagaattt
    93781 tttctaacta aaaataatag cacaatcttt ggcagcaatc tgaattgttt ttccataaaa
    93841 gatttaagca cttacgtttg cttaaaatat aggttatgtg acgtgcgtgc aagatcagat
    93901 tataacaaaa tagttccaaa taagcctatc actgagaaag catcacagaa gggttaaact
    93961 ttttttgtat tagtgtttta tcagtacaac ctaacactta tttttataaa aaaataaaaa
    94021 agctattgac aatcttatac aagataacgt atactaataa agctgttgta aatatggtaa
    94081 agcaatagat gctatcagga aaaaatgtga a
//
LOCUS       DAUGUF010000002        84866 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUGUF010000002 DAUGUF010000000
VERSION     DAUGUF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84866
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.002"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            134..2332
                     /gene="nrdD"
                     /locus_tag="VIB71_000092"
     CDS             134..2332
                     /gene="nrdD"
                     /locus_tag="VIB71_000092"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEQ8821855.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYTIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACENWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            2514..2660
                     /locus_tag="VIB71_000093"
     CDS             2514..2660
                     /locus_tag="VIB71_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821856.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            2689..3624
                     /locus_tag="VIB71_000094"
     CDS             2689..3624
                     /locus_tag="VIB71_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8821857.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTNLDGVFIHAATKAHVDLASLFLRQGIPVFMDKPLADNYDSV
                     KYLYELAEAHHTFLMAGFNRRFAPCVKELSSLSTKRKVAAEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            3633..4142
                     /locus_tag="VIB71_000095"
     CDS             3633..4142
                     /locus_tag="VIB71_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8821858.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLASQGVPAIQYVAFDEKNQALGFLNLRLRLNASLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSCAISKNITTILVTCDETNVASRAVIVANGGVLEDSRGGTERY
                     WIEEQRGDK"
     gene            4142..4756
                     /gene="nrdG"
                     /locus_tag="VIB71_000096"
     CDS             4142..4756
                     /gene="nrdG"
                     /locus_tag="VIB71_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEQ8821859.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRCELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLF"
     gene            complement(4930..5661)
                     /gene="yaaA"
                     /locus_tag="VIB71_000097"
     CDS             complement(4930..5661)
                     /gene="yaaA"
                     /locus_tag="VIB71_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEQ8821860.1"
                     /translation="MLTFLIPTAKEMVIPKESYPHLLPQPSQAILKAMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGRFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(5796..6551)
                     /locus_tag="VIB71_000098"
     CDS             complement(5796..6551)
                     /locus_tag="VIB71_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8821861.1"
                     /translation="MTYPYNSTISLGKVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLHFLTRGISLEGAADHGY
                     SEAIYLSDPEGNGIEIYHDKAVEQWDIRDNGQIIGVTEPTDTKSILEQLTDIPKHFLL
                     AQDTRISHVHLSVKNALDSSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHWSAP
                     YLKKHQEGTPGLAFLTIHIETPLLFSATLKKAR"
     gene            6737..7075
                     /locus_tag="VIB71_000099"
     CDS             6737..7075
                     /locus_tag="VIB71_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8821862.1"
                     /translation="MLKKRPACPVETTLSVIGNKWKLLILRDLLKGTLRFGQLKSSIG
                     SVSQKVLTAQLRAMEADGLVHRELYAEVPPRVEYSLTETGLSLAPVIEAMSDWDQTYQ
                     EKHADLFEEG"
     gene            complement(7354..8067)
                     /gene="treR"
                     /locus_tag="VIB71_000100"
     CDS             complement(7354..8067)
                     /gene="treR"
                     /locus_tag="VIB71_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEQ8821863.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFSRRRPK"
     gene            8278..10302
                     /gene="treP"
                     /locus_tag="VIB71_000101"
     CDS             8278..10302
                     /gene="treP"
                     /locus_tag="VIB71_000101"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEQ8821864.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWIIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFDVQANSIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLAETPVSE
                     APAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGVLLQPTEGVLVAP
                     CDAEVSVLFPTKHAIGLVTAEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATEMPLVVTNQDTFTVTVEGSLPHQIKANDKLVVAVKK"
     gene            10369..11997
                     /gene="treC"
                     /locus_tag="VIB71_000102"
     CDS             10369..11997
                     /gene="treC"
                     /locus_tag="VIB71_000102"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEQ8821865.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDNYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILADN"
     gene            12205..14100
                     /gene="pepO"
                     /locus_tag="VIB71_000103"
     CDS             12205..14100
                     /gene="pepO"
                     /locus_tag="VIB71_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEQ8821866.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGENIPDDAILANFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYAWA
                     DFTKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDEIRVQSGTYARALSGTPQAMDKQKAAFYLAQGPFNQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDETLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQAPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNITLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(14267..15307)
                     /locus_tag="VIB71_000104"
     CDS             complement(14267..15307)
                     /locus_tag="VIB71_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEQ8821867.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(15441..16208)
                     /gene="rpsB"
                     /locus_tag="VIB71_000105"
     CDS             complement(15441..16208)
                     /gene="rpsB"
                     /locus_tag="VIB71_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEQ8821868.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            16512..19586
                     /locus_tag="VIB71_000106"
     CDS             16512..19586
                     /locus_tag="VIB71_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8821869.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNMQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLAYINSQLGSQPVTAEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVTY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(19617..20603)
                     /locus_tag="VIB71_000107"
     CDS             complement(19617..20603)
                     /locus_tag="VIB71_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEQ8821870.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASRKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS"
     gene            complement(20789..22330)
                     /gene="hutH"
                     /locus_tag="VIB71_000108"
     CDS             complement(20789..22330)
                     /gene="hutH"
                     /locus_tag="VIB71_000108"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEQ8821871.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCIPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KSENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASTVIEDPSFLEAVEQTVE
                     LSIQF"
     gene            complement(22341..23693)
                     /locus_tag="VIB71_000109"
     CDS             complement(22341..23693)
                     /locus_tag="VIB71_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEQ8821872.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCVCTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIILLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMDQMPPKEQI
                     "
     gene            complement(23913..24509)
                     /locus_tag="VIB71_000110"
     CDS             complement(23913..24509)
                     /locus_tag="VIB71_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEQ8821873.1"
                     /translation="MTTVMVKTPADYTQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     KSTVALRQTTFTLLDGYHRILMTLDKPITLSDLSHAKEISLTPFEPYAFEGDTRIVSR
                     GICQDINLMYDDQYQGQLLPVWSDTLFETPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCPNQTSPAQTPVAVWAGLWYKT"
     gene            complement(24531..26204)
                     /locus_tag="VIB71_000111"
     CDS             complement(24531..26204)
                     /locus_tag="VIB71_000111"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8821874.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDAR
                     QLVALKNKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     HLEKIIIGYNFQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFRFVYNEDDSIETKLT
                     KIVTKVYGGKGIKLTPTAKRELAELERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFI
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(26222..26848)
                     /locus_tag="VIB71_000112"
     CDS             complement(26222..26848)
                     /locus_tag="VIB71_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEQ8821875.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQDIIEDLHTKSSRLQQDLLDAIDKDTEAFNLVSDVFDMPKETDEDKA
                     ARRTAMQKTLKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(26859..27758)
                     /gene="ftcD"
                     /locus_tag="VIB71_000113"
     CDS             complement(26859..27758)
                     /gene="ftcD"
                     /locus_tag="VIB71_000113"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEQ8821876.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGITAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEIIGLAPAKALIDV
                     AEYYLQVEDFDYHKQILENHLLG"
     gene            complement(27846..29876)
                     /locus_tag="VIB71_000114"
     CDS             complement(27846..29876)
                     /locus_tag="VIB71_000114"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEQ8821877.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRSPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPIDEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKSVAI
                     IAEVDQSRIETRHSQGWVSQIAESPEEALQLARKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVREGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            30167..31432
                     /locus_tag="VIB71_000115"
     CDS             30167..31432
                     /locus_tag="VIB71_000115"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEQ8821878.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITNDDIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(31490..33022)
                     /gene="ahpF"
                     /locus_tag="VIB71_000116"
     CDS             complement(31490..33022)
                     /gene="ahpF"
                     /locus_tag="VIB71_000116"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEQ8821879.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHDSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     ADTANMTIIKNVATKDIVGDDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(33043..33603)
                     /gene="ahpC"
                     /locus_tag="VIB71_000117"
     CDS             complement(33043..33603)
                     /gene="ahpC"
                     /locus_tag="VIB71_000117"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEQ8821880.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            34009..34079
                     /locus_tag="VIB71_000118"
     tRNA            34009..34079
                     /locus_tag="VIB71_000118"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34041..34043,aa:Cys,seq:gca)
     gene            34598..34801
                     /locus_tag="VIB71_000119"
     CDS             34598..34801
                     /locus_tag="VIB71_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEQ8821881.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            34997..35458
                     /locus_tag="VIB71_000120"
     CDS             34997..35458
                     /locus_tag="VIB71_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEQ8821882.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAMASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            35458..37902
                     /locus_tag="VIB71_000121"
     CDS             35458..37902
                     /locus_tag="VIB71_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8821883.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            38080..38370
                     /gene="groES"
                     /locus_tag="VIB71_000122"
     CDS             38080..38370
                     /gene="groES"
                     /locus_tag="VIB71_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEQ8821884.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            38406..40037
                     /gene="groL"
                     /locus_tag="VIB71_000123"
     CDS             38406..40037
                     /gene="groL"
                     /locus_tag="VIB71_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEQ8821885.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            40288..40554
                     /locus_tag="VIB71_000124"
     CDS             40288..40554
                     /locus_tag="VIB71_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8821886.1"
                     /translation="MNHFGEILKTFRESKGLRLKDVAKAGISTSQLSRFEKGETDLTI
                     STFMLILDESNMPIDEFMYAVHDFHRDDLNELLSKSEAFRNNSR"
     gene            complement(41266..42765)
                     /locus_tag="VIB71_000125"
     CDS             complement(41266..42765)
                     /locus_tag="VIB71_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8821887.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYIEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVKEKPKNKKGLNRS"
     gene            43012..44652
                     /locus_tag="VIB71_000126"
     CDS             43012..44652
                     /locus_tag="VIB71_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821888.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTIYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALAPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(44741..45742)
                     /locus_tag="VIB71_000127"
     CDS             complement(44741..45742)
                     /locus_tag="VIB71_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8821889.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTREDICVQAKSATFDAVLNAQKARK"
     gene            46318..46698
                     /locus_tag="VIB71_000128"
     CDS             46318..46698
                     /locus_tag="VIB71_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8821890.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            46737..49073
                     /locus_tag="VIB71_000129"
     CDS             46737..49073
                     /locus_tag="VIB71_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8821891.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            49122..49274
                     /gene="rpmG"
                     /locus_tag="VIB71_000130"
     CDS             49122..49274
                     /gene="rpmG"
                     /locus_tag="VIB71_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8821892.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            49288..49464
                     /gene="secE"
                     /locus_tag="VIB71_000131"
     CDS             49288..49464
                     /gene="secE"
                     /locus_tag="VIB71_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEQ8821893.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(49701..50474)
                     /locus_tag="VIB71_000132"
     CDS             complement(49701..50474)
                     /locus_tag="VIB71_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEQ8821894.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KVPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            50600..51346
                     /locus_tag="VIB71_000133"
     CDS             50600..51346
                     /locus_tag="VIB71_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8821895.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLDVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKVITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            51362..52342
                     /locus_tag="VIB71_000134"
     CDS             51362..52342
                     /locus_tag="VIB71_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEQ8821896.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRQQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            52629..52949
                     /locus_tag="VIB71_000135"
     CDS             52629..52949
                     /locus_tag="VIB71_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8821897.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLVKEIIDLRKE
                     LATK"
     gene            52977..53285
                     /locus_tag="VIB71_000136"
     CDS             52977..53285
                     /locus_tag="VIB71_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8821898.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDQSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            53295..54599
                     /locus_tag="VIB71_000137"
     CDS             53295..54599
                     /locus_tag="VIB71_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8821899.1"
                     /translation="MAKMNMQNIIMPIMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGINDAIAGVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEPVGDAISKAWFGGQGIIGAIVIGLTVGAIYTAFIR
                     RHIVIKMPEQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            54810..57227
                     /locus_tag="VIB71_000138"
     CDS             54810..57227
                     /locus_tag="VIB71_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEQ8821900.1"
                     /translation="MTETKSPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEASIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGQLTPEELWQALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            57240..57908
                     /locus_tag="VIB71_000139"
     CDS             57240..57908
                     /locus_tag="VIB71_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ8821901.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYKGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYSTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKLLAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            57965..59053
                     /locus_tag="VIB71_000140"
     CDS             57965..59053
                     /locus_tag="VIB71_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEQ8821902.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGNSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(59135..59644)
                     /locus_tag="VIB71_000141"
     CDS             complement(59135..59644)
                     /locus_tag="VIB71_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEQ8821903.1"
                     /translation="MSTDHHLREVSYQLLAERGGSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGNSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            60008..60823
                     /gene="sdaB"
                     /locus_tag="VIB71_000142"
     CDS             60008..60823
                     /gene="sdaB"
                     /locus_tag="VIB71_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEQ8821904.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(61064..61906)
                     /gene="ropB"
                     /locus_tag="VIB71_000143"
                     /gene_synonym="rgg1"
     CDS             complement(61064..61906)
                     /gene="ropB"
                     /locus_tag="VIB71_000143"
                     /gene_synonym="rgg1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="RopB (Regulator of Protease B) is a paralog of the
                     quorum-sensing transcriptional regulators Rgg2 and Rgg3,
                     which bind short, hydrophobic peptides encoded by genes in
                     their respective vicinities. RopB binds the leaderless
                     short peptide SIP (SpeB-inducing peptide), with sequence
                     MWLLLLFL; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     RopB/Rgg1"
                     /protein_id="HEQ8821905.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIDGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            62405..62575
                     /locus_tag="VIB71_000144"
     CDS             62405..62575
                     /locus_tag="VIB71_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821906.1"
                     /translation="MDNPKKDKGFSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            62847..64043
                     /gene="speB"
                     /locus_tag="VIB71_000145"
     CDS             62847..64043
                     /gene="speB"
                     /locus_tag="VIB71_000145"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEQ8821907.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            64045..64350
                     /locus_tag="VIB71_000146"
     CDS             64045..64350
                     /locus_tag="VIB71_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEQ8821908.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMVEAYQKQINSLD"
     gene            64830..65759
                     /gene="prsA"
                     /locus_tag="VIB71_000147"
     CDS             64830..65759
                     /gene="prsA"
                     /locus_tag="VIB71_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8821909.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTTEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKITYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(66030..66266)
                     /locus_tag="VIB71_000148"
     CDS             complement(66030..66266)
                     /locus_tag="VIB71_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821910.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPTAHGPCD
                     DTHQLLEDKSLSDDYLITTSAMRRLWYWGYSQIG"
     gene            66750..68930
                     /locus_tag="VIB71_000149"
     CDS             66750..68930
                     /locus_tag="VIB71_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEQ8821911.1"
                     /translation="MLIAPTVLGQEVSNTEASASSTASVDATASGTTASGASSEATVA
                     TTNGGSQSTQVAAETTPQPQVQTSEQPAATSTSLASSTSSSEDKAPKAASTKSSSATV
                     ASSSNGSNQGAGTEVEPQMMDVEQYKVNKEKTELTVKDDNQQLKIRKDVDELKNKDLF
                     DVKREVKDNGDGTLDVTLKVTPKQIDEGADVMALLDVSQKMTDADFNNAKEKIKKLVK
                     TLTSKPTDSHPNHNARNSVRLMTFYREVSDPIDISGKTDEELNKILDDVWQNAKHNWD
                     WGVDLQGAIHKARGIFKQDQEKKSGKRQHIVLFSQGESTFSYDIQKSEKERDNNLSRI
                     NEKITSSNPLLHWPPIFNHTHQNADMLNEIERIIKIGEQLGIKGLSSIKGYLSTAAAG
                     SGILGNFIGGGSLTEYLTLKEYNSDKLEESQFDYTKRVGEGYYYYSFSKRVSHNDFPF
                     KTLIEQAITQAIPTKGESKNWFEKFLDKFSLVESYRDTQKKALLKILEYLFYKREYHY
                     YNHNLSAIAEAKMAQQEGITFYSVDVTDSETTPKRVRRQTAVRQEKAKKESKEERNEK
                     FDKYLKKMSEGNTFLDSVEEKDKFKDTFTNVTVTETFEDKVSAIANSWESSLDSHNNK
                     SDRNHKGSVKHTQAQSSGWFANTQESLTWTISKDQLKKAFEDGEPLTLTYKLKVDKDK
                     FRETLKKQQERNRKNEQHLRKVRTLSQKKLFQIRFLTRLIMVRI"
     gene            68957..69748
                     /locus_tag="VIB71_000150"
     CDS             68957..69748
                     /locus_tag="VIB71_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8821912.1"
                     /translation="MSYSKFKMPIPELDIEVVPIPEKPLVEPMTPLYPAIPNYPTPQL
                     PKDEDLEISGGHGPIVDIVEDTGTGVEGGSQNGVVSTQENKDPIVDITEDTQPGMSGS
                     NDATVVEEDTAPKRPDVLVGGQSDPIDITEDTQPSVSGSNDATVVEEDTAPKRPDILV
                     GGQSDPIDITEDTQPGMSGSNDATVIEEDTKPKRFFHFDNEPQAPEKPKEQPSNSLPQ
                     APVYKAAHHLPASGDKREASFTIVALTIIGAAGLLSKKRRDTEEN"
     gene            69928..71895
                     /locus_tag="VIB71_000151"
     CDS             69928..71895
                     /locus_tag="VIB71_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8821913.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAISNSLEYQAQYKRVKEE
                     LDALKEKGPKLGERSLYFKVVNRFLGWFGVVWDPLAIKETDHLLDLIGQVNYLVSNTE
                     FQAPEYQKAKNKLDLAVAGYDLYLAREKKRGDAPDYQVTQLTLGQLETIKTKIQEALK
                     TFAQEVKTIQQKKPDLFPHAYVLNAKSKDITDKAQPFLVNGYYDVFYKQFLFTNTNDG
                     YNYNKEADNLASYQKLIKELLGLKAEIDQLTKDDPKNDRLETLMWESKFTLSDSRRTS
                     RLSAYYTQEDYVKKVVLSEEAPNLRTAKEKVKTLKGILHDYYVDIKEPEKAKKYRVED
                     ETLPSQPEAPAKPEAPAPSPSPAPGQKPAEDERSSQATEPANPSKENSSTDASQGSHD
                     SENPATDSPSQPQASDQGNHQSQVPNAKPQTDKTDTPNAPVPPQNTPNAPAIPQDTPK
                     VPEAGGQSGPAGNAEEKAPDSGPKESGQSSSKESPSVGEDTTPNQPDVLVGGQREPID
                     ITEDTITDAPPTVSGHNASTQPQSVVEDTAPQRPDVLVGGQSEPIDITQDTQPGMSGS
                     NDATVINEDTKPKRVFHFDNKEPQASEKAAEQKLAPHDSHTTPQTSDDTAAPHLPASG
                     DKPEKVFALAALTMVAAAGLLSKKRRNTDKN"
     gene            72037..72333
                     /locus_tag="VIB71_000152"
     CDS             72037..72333
                     /locus_tag="VIB71_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEQ8821914.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            72481..72765
                     /locus_tag="VIB71_000153"
     CDS             72481..72765
                     /locus_tag="VIB71_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEQ8821915.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            73189..74457
                     /locus_tag="VIB71_000154"
     CDS             73189..74457
                     /locus_tag="VIB71_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8821916.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGTYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATMEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEVKTKPFSKGYIE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            74444..75118
                     /locus_tag="VIB71_000155"
     CDS             74444..75118
                     /locus_tag="VIB71_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8821917.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            75131..76348
                     /locus_tag="VIB71_000156"
     CDS             75131..76348
                     /locus_tag="VIB71_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8821918.1"
                     /translation="MEDIIAALGSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            76442..77095
                     /locus_tag="VIB71_000157"
     CDS             76442..77095
                     /locus_tag="VIB71_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8821919.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            77092..78480
                     /locus_tag="VIB71_000158"
     CDS             77092..78480
                     /locus_tag="VIB71_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8821920.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKPGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            78582..80210
                     /locus_tag="VIB71_000159"
     CDS             78582..80210
                     /locus_tag="VIB71_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8821921.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTAD
                     TDTDDESETAKKDKKSKETASQHDTQKDHKSSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNVTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKT
                     PEKGPEKATEKTPEPNRDAPKPIQPPLAAAAPVFAPWRESDKDLSKLKPSSRSSAAYV
                     RHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVR
                     AIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIAN
                     KNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTP
                     EIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVD
                     RYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILIS
                     ESNVMGLGTISYRTFTAEQASLLTYVVGGKLPRP"
     gene            80288..80539
                     /locus_tag="VIB71_000160"
     CDS             80288..80539
                     /locus_tag="VIB71_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821922.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            81215..82846
                     /gene="mga"
                     /locus_tag="VIB71_000161"
     CDS             81215..82846
                     /gene="mga"
                     /locus_tag="VIB71_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Mga"
                     /protein_id="HEQ8821923.1"
                     /translation="MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISML
                     TLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFR
                     DFNSLEELAEELFVSLSTLKRLIKKTNAYLTHTFGITILTSPVQVSGDEHQIRLFYLK
                     YFSEAYKISEWPFGEMLNLKNCERLLSLMIKEVDVRVNFTLFQHLKILSSVNLIRYYK
                     GYSAVYDNKKTSHRFSQLIQSSLEIQDLSRLFYLKFGLYLDETTIAEMFSNHVNDQLE
                     IGYAFDSIKQDSPTGCRKVTNWVHLLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDI
                     TANYLFFDYKKSYLNFYKQEHPHLYKACVAGVEKLMRSEKEPISKELTNQLIYAFFIT
                     WENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYIGEFFSITNFNELDALTIDLEEIE
                     KQYDVIVTDVMVGKSDELEIFFFYKMIPEAIIDKLNAFLNISFADSLPLDKPIKNPLD
                     FHRKEVILPTPPNKLHAPLHNLDSLTAATQKQIHH"
     gene            82990..84717
                     /gene="emm"
                     /locus_tag="VIB71_000162"
     CDS             82990..84717
                     /gene="emm"
                     /locus_tag="VIB71_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein"
                     /protein_id="HEQ8821924.1"
                     /translation="MAKNTTNRHYSLRKLKTGTASVAVALTVVGAGLVAGQTVRADHS
                     DLVAEKQRLEDLGQKFERLKQRSELYLQQYYDNKSNGYKGDWYVQQLKMLNRDLEQAY
                     NELSGEAHKDALGKLGIDNADLKAKITELEKSVEEKNDVLSQIKKELEEAEKDIQFGR
                     EVHAADLLRHKQEIAEKENVISKLNGELQPLKQKVDETDRNLQQEKQKVLSLEQQLAV
                     TKENAKKDFELAALGHQLADKEYNAKIAELESKLADAKKDFELAALGHQHAHNEYQAK
                     LAEKDGQIKQLEEQKQILDASRKGTARDLEAVRQAKKATEAELNNLKAELAKVTEQKQ
                     ILDASRKGTARDLEAVRKAKAQVEAALKQLEEQNKISEASRKGLRRDLDASREAKKQV
                     EKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEK
                     LNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDAK
                     PGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEAANPFFTAAALTVMATAGVA
                     AVVKRKEEN"
BASE COUNT        26701 a        16492 c        17895 g        23778 t
ORIGIN      
        1 aacgacaaaa agttttattg tttatcagaa aaagtaattt aatatcaata tattgtgttc
       61 gagcaaaaaa cttgacacaa tatattgatt tttttagttg tcgtgatata atagttccgt
      121 aaggagattt gatatggtaa gtttagaaga agacaaggtg actgttcaac ctgatattaa
      181 agtgattaaa cgagatggtc gccttgttaa ttttgatagt acaaaaatct atagtgcttt
      241 attaaaagca agcatgaaag taactcggat gtcgccactt gttgaggcta aattagaggc
      301 tatttctgat cgcattatag cagaaattat tgagcgtttt ccaactaata tcaaaattta
      361 tgaaatccaa aatattgtag agcataagct tcttgcagct aatgaatata ctattgcaaa
      421 agaatacatt aattatcgta ctcagcgtga ctttgcacgt tcacaagcaa cagatatcaa
      481 tttttctatt gataaattaa ttaataaaga tcaaacagtt gttaatgaaa atgctaacaa
      541 agatagcgat gtttttaata ctcaacgaga tttaactgct ggaatcgtag ggaaatcaat
      601 tggtttaaaa atgttacctt cgcatgttgc taatgctcat caaaaaggag atatccatta
      661 ccatgatttg gattacagtc cttatacacc gatgacgaac tgctgtttaa ttgactttaa
      721 gggcatgtta gccaatggct ttaaaattgg taatgctgaa gtggaaagtc ccaagtctat
      781 tcaaactgca acagctcaga tctcacagat tattgcgaat gtagcatcaa gtcagtacgg
      841 cggatgcaca gctgatcgca ttgacgagtt tttagcccca tatgcggagc ttaactttaa
      901 aaaacatatg gctgatgcta agaaatggat cgttgagact aagagagaaa gctatgcttt
      961 tgaaaagact caaaaagata tttatgatgc gatgcagtct ttggaatatg aaattaatac
     1021 gctctttacg tctaatggtc aaacaccatt tacttcttta ggatttggtt tggggacgtc
     1081 ttggtttgaa cgtgagattc aaaaagctat tttgaccatt cggattaatg gtcttggtag
     1141 tgaacatcgc acggctattt tccctaaatt aatttttacg gttaaacgtg gcttgaattt
     1201 agaaccagat tcaccaaact atgatattaa gactttggct ttagaatgtg cgactaagcg
     1261 gatgtacccg gatatgttat cttatgataa aattattgat ttgacaggat ctttcaaatc
     1321 tccaatggga tgccgctctt tccttcaagg ctggaaagat gaaaatgggc aagatgtgac
     1381 ctcaggccgt atgaatcttg gggttgtcac cctcaattta cctcgcattg ccatggaatc
     1441 aaatggcgat atggataagt tttgggagct gtttaatgag aggatgctaa ttagtaagga
     1501 tgctttaatt tatcgtgtcg aacgtgtcac agaagcaaaa ccagcaaatg cccctattct
     1561 ttatcaatat ggtgcttttg gaaagcgttt ggagaagaca gggaatgtaa atgatctctt
     1621 taagaatcgt cgtgcaacag tctctcttgg ctatattggc ctttatgaag tggcgtctgt
     1681 tttttatggt ggtcaatggg aaggtaatcc agatgctaaa gcttttacct tgtcaattgt
     1741 caaggcaatg aaacaggcct gtgagaattg gtcagatgaa tatggttatc atttctctgt
     1801 ttattcgact ccatcagaaa gtttgacaga tcgcttttgt cgtttagata cggaaaaatt
     1861 tggcattgtg acagatatta cggataaaga atactataca aattcttttc actatgatgt
     1921 gcgtaagagt ccgacacctt ttgaaaaatt agattttgaa aaagattatc cagaagcagg
     1981 tgcttcaggt ggttttatcc actactgtga gtatcctgtt ttgcaacaaa atccaaaggc
     2041 cttggaagcg gtttgggact atgcttatga tcgtgtgggg tatttgggaa ccaatacgcc
     2101 tattgataaa tgctataatt gccaatttga aggtgatttt accccaacag aacgtggttt
     2161 tacttgccca aactgtggca ataatgaccc taaaacagtt gatgtggtca aacgtacatg
     2221 tggttacttg gggaatcctc aggcccgccc aatggttaac ggtcgccata aggaaatctc
     2281 tgcgcgtgta aaacatatga atggttctac tataaaatac ccaggcctgt aaactcaagc
     2341 tgggggagag cccttttgat ggaaatatga tatgcttaaa aggttgcttc atgcaagcaa
     2401 tcttttattg tctaatggtt tcttagcaat tgtgagataa gaataactaa tccaaaacga
     2461 ctaattagct gttagcaatc ggactataag aagaaagaga taaggaagaa ataatgggaa
     2521 aatatcaatt agactataaa ggaatgcagc aggtagaacg ctttcatgag aagcattcta
     2581 aaaaaaagac ggataaaaaa tcccgcgttc aagaacttaa ggctcggttt ttagagaagt
     2641 caaaaaaaca ggataactaa agtatccaat aaagaaagaa ggttgagtat gcttaatatt
     2701 gggattgtgg gactaggtgc catttcacaa aaagcctatt taccatatat gagacagctg
     2761 agtgacatta cttggcatct atcaacgcgg aatgcagcag tacgtcagca ggtcggtcag
     2821 ttatttggtc acgctattct ttacagtgat gtcaaggagt tgtcaaaaac aaacttagat
     2881 ggggtcttta ttcatgctgc gacaaaagct catgttgatc tagcaagctt atttctaaga
     2941 caaggtattc cagtatttat ggataagcca ttggcagata actacgactc agtaaagtat
     3001 ctatacgagt tggctgaagc tcatcacact tttttaatgg ctggttttaa taggcgcttt
     3061 gcaccatgtg tcaaggaatt gtcaagtttg tcaactaagc gtaaagtggc ggctgaaaaa
     3121 aatgacttga atcggccagg agatatgact tttaagctct ttgatttctt tatccatcct
     3181 ttagatacag ccttattctt gacagaaggg accttactaa aagggcattt tcaatatcat
     3241 ctggaagcag gcttactgag ccaagttatg gtaaccttga tgaccgaaag catgacgact
     3301 acagcttcta tgaatttaca atcagggagt cgccgtgagg taatggaagt tcaacgggct
     3361 gaagaaactt atcatttaga gaacttagac gagttatcta tttataaagg tactgaaaaa
     3421 agggtgcttg gctttgcttc ttgggacact accttgcaca aaagaggttt tgaaacaatg
     3481 atcgatgcct ttttagaagc tattagcaca ggcgtcaatc ctgtcagccc tgagtctagt
     3541 cttttaagcc actggatttg tcaacagatt gctgactctc agctttctta tggagagtta
     3601 acggtagagt tgcctaagga ttaggaattg atatggaaat aagacgaccg actttaaaag
     3661 ataaagatgc tgtattgtca atgattaacg aatttttaga gcagaaaagt gctacagatg
     3721 ggttatggca ttttaacgtc aatgacttca actatgaaac atggttggaa gattccttgc
     3781 gacaggaaat gggtttggcc agtcaaggag tgcctgctat tcaatatgtg gcgtttgatg
     3841 agaaaaatca agctttggga tttttaaacc ttaggttacg tttaaatgcc tcgttacttg
     3901 aaaaaggtgg gcatattggt tactctgtcc gtcccagcca gcgtgggaaa ggttatgcca
     3961 aggagatgct taaacaagct gtcagctgtg cgatttccaa gaatatcacg acaattttgg
     4021 taacttgtga tgagactaat gttgcaagcc gagcagttat tgtggctaac ggcggtgtct
     4081 tggaagatag tcgaggtgga acggaacgtt attggattga agaacaaaga ggcgataagt
     4141 gatggcagaa aagtgttgga ataatcctaa gccaaaggaa tggcaggcag aggagttaag
     4201 tcaaggccgg attattgact ataaggcttt taactttgtt gatggtgaag gggttcgtaa
     4261 ttccctttat gtgtctggtt gtttattcca ttgcaagggg tgttataatg ctgcgacttg
     4321 gtcttttaag gcgggaatgc cttatacgca agaacttgaa gagcagataa tgacggattt
     4381 ggcacagcct tatgttcagg gactgacact tttaggtgga gaaccctttt tgaatacggg
     4441 tatcttaatt cctctgatta agcgtattcg gtgtgaattg ccagaaaaag atatttggtc
     4501 ttggacgggt tatacttggg aagaaatgat gcttgaaaca ccagacaaac tggaaatgct
     4561 gtccttaatt gatattctgg tagatggtcg ttttgatatc acaaaaaaga acctcatgtt
     4621 gcaatttaga ggctcttcta accagcgaat tatcgatgtt caaaagtctt tggctgctaa
     4681 agaagtgatt atctgggata agttaaacga tggggaccaa acctttgaac aaattagtcg
     4741 ggaggatttg ttttaagaag ctgacttatc cacatgattt ttttgaaaag gtcatgtgaa
     4801 aacaggtcct ttaagggtga attggggaga aagtaattgt tattccctgg ttttccccac
     4861 attatcctca tagttatcca caggttgtgt ataagttgta gacttgtgaa taaagactaa
     4921 aaaagaggcc taggcttctt ttttgatata gacaaattca tgatctgttg ataggtctgg
     4981 atggtagtaa aaaccagcaa agacaaggct tttaaggctg tcaacagttt ggcaattatt
     5041 ttccatacag gcagtgagaa atgcacctcg tgcctttttt gaaatggtgg aatgggtttt
     5101 gaatcggccc tctttttctg ccataaactt gggacttatc cacaattgtt tacagtcttt
     5161 ggaaaagaca tcgtcaaatt cactggataa aagggaaatc acttggggat gctctttggc
     5221 aaactgatta taacagggcc gccagtaaga cttgaggctt tgtccttcaa tttttattct
     5281 ggtgtgaaaa tcatggcggt gctctgcgat agggtgatta gcgggaatga taccgtaaaa
     5341 ggatgaggtg atgtaaacct gctgggtgag gtaagcctgt tcttgggtag tgagcttatc
     5401 gcgcttgata tggcggtaca taaggccatt gaacagttgg taggcagggt aagcgaggct
     5461 ttgttgagag gccatgtctt gccagcgttg ctgttctttt ttagctgcct cttctttgat
     5521 acgatatgat ttggccaagt cctctgtggt catagctgcc attgccttta aaatggcctg
     5581 gcttggttgg ggcagtaggt gtggataaga ttctttagga atcaccattt cttttgcggt
     5641 tggaattaaa aaggttagca tagtgttatt gtagtaaagt tacttgcttt ctgtcaagaa
     5701 aactagtctt gtccaaggat gacgtccaca cggatacctt cctcgtcttc tgtcatgaaa
     5761 gaagaagaat cttcttgtaa aatagctagg ccatatcatc tggctttttt gagagtagct
     5821 gaaaaaagca ggggcgtctc aatgtgaatg gttaagaagg ctagacctgg agtgccttct
     5881 tggtgttttt tgaggtaagg ggctgaccag tgattgaatg caaggtgatg atggtagttc
     5941 cctgaagcaa tccagctagc acttggaatg gtcattttat cgcctaaatc aaaaaccttt
     6001 tgatagagaa gtgaagaatc cagagcattt ttgacactca gatggacatg actaatgcgt
     6061 gtgtcttgag ctagtaaaaa gtgcttgggg atatctgtca actgctccaa tatgcttttg
     6121 gtatccgtgg gctcagtcac accaataatt tgaccattgt cgcggatatc ccactgctca
     6181 acagctttgt catgatagat ttcaatccca ttaccctcag gatcgctgag gtagatagct
     6241 tcgctatagc cgtgatcagc tgctccttct aaagagatac ctctggttaa gaaatgaagt
     6301 cccaagctat gacgatcagg aactaaaaag gctgtgtgat aaagaccata agccttattt
     6361 gctggtaaag gtgtttgtcg taactctaag ataacggttt taccgtctgt agtcaattga
     6421 cgagatgtcg tgtcttgtga gagaacctgt aaaccgataa tacttgtgta aaaggttgtc
     6481 atctttgcta gatcggtaac attgagggaa acctttccta gagagatggt tgagttgtaa
     6541 gggtatgtca tcctattgtc tccaaaagtg attaagccta tgataactta ttagtttcaa
     6601 aaagaaaagt aggcacaaat aagtggtata ggcactaaaa agtaactcat ttgtcagccc
     6661 tatcttgttt ctgttctctc taatagtcta taatgggtta taagttacaa aaagatacta
     6721 agaggagctg ctgcctatgc tgaaaaaaag accggcttgt cccgtagaaa caaccttatc
     6781 ggtaatcggg aataaatgga aattattaat attaagggac ttgctaaagg ggaccttgcg
     6841 ttttgggcag ttgaagtcct caataggttc ggtcagtcaa aaggtactta ctgcccaatt
     6901 aagggctatg gaagcagacg gattggttca tcgggaattg tatgcagaag tgccacctcg
     6961 ggtggagtat tccttaacag aaactgggtt gagcttagct cctgttattg aagcgatgtc
     7021 ggattgggac caaacttacc aagaaaaaca tgccgattta tttgaagaag gctagaggaa
     7081 agagttgtcc gagcatactg agacttagag aagctgagag tttttttaaa atgatattat
     7141 caaattcttt acagtttgat aaaattactt tttttctaca aaaagacttg cgctcatctc
     7201 acgaatatga taatataata tcaagtctgt ttgagaaaac agaagctcag gtcaagtaag
     7261 tgcacactta caataacaca gttgataatg gggaaactca gagtcaagaa aaagaaaagc
     7321 aagccttgca ttttgcaagg cttttttctg tctttatttt ggtctgcgcc gagaaaaatc
     7381 taaaaattta aatttttcca gtttatggcg actctcggtg aattggaatt ggttattatt
     7441 ggaaaggtaa actttggatt tgacggaaac aacatgttgg tctgatccaa ggtcaagtaa
     7501 aattttatca cgatcggtta tttggtcaat ggtaacctct ttgagggcaa agtcaatggc
     7561 gagatggagt tccttttcca aatattgata aatagaatgc tctgcgattt cccttgtcat
     7621 tattggcacc aaagttttac taaggtaatc aatgtctaag acggaagcca caccctcaac
     7681 aacgcgttgg cgcgtaacac gccagaccaa gctgtttttg ctaaaaccgg tcaattttga
     7741 aagtgtctca tccacaatca gtttatcaat ggcaatgacg ttggtcttag aatctagatt
     7801 tgagtaagag acgagttcct gataactagt tagttctgag atagggaaca tgatctgatg
     7861 atgtttaatc acttgggtgc cacgtccttg ttttttgagg ataagacctg cctttgtgag
     7921 aagtgagaga gccttgcgga cggtatctcg gctagcttgg tattgttgac tcaattctat
     7981 ttcagtaggt aaaaaatccc cttctttgta aaagtctttg tttatttttg tttcgaggtc
     8041 tttataaata cgttcatact ttgtcatagg gtaaattacc tttccacttg tctatttttt
     8101 tacagacaac accttttatt ttaccaaaat aatggctttt ttggcacaaa caacttgcag
     8161 acaaatttgc aatcgattac aataaaggtg tcaatcatat tttatctaag aatttgaata
     8221 tttcattttg acgttgcttg ttaaaagcaa ctagaacaaa ggactagggg atgtcacatg
     8281 ggaaaatttg aacaggatgc taaaagtctt ctaactgcta ttggcggtaa agaaaacatc
     8341 aaggctgtca cacactgtgc aacgcgtatg cgttttgttt tgaatgataa taataaggca
     8401 aatgtcaaag agattgaaaa aatctctgta gttaaaggga catttaccaa tgctgggcag
     8461 tttcaggtaa tcattggtaa tgatgttcca gttttttata atgactttac agctgtttct
     8521 ggtattgaag gggtgtctaa agaagctgcc aaatcagcag ctaaaagtaa tcaaaatgcc
     8581 ttacaacggg tgatgaccat gttggctgag attttcacac ctattattcc ggcgattatt
     8641 gttggggggc ttattttagg tttccgtaat attttggaga gtgtgccttt tgaatttctt
     8701 gggcagcagg tcgaaaaagg gaaattagtt tttgatgcag ctggggatcc tgtttggaat
     8761 acgattgtga gggtatctcc tttctggtca ggggttaacc atttcttgtg gttaccaggg
     8821 gaagctattt tccacttctt accagttggg attacttggt ctgtgacgcg taagatggga
     8881 accactcaaa ttttagggat tgtccttggt atctgtttgg tgtcaccaca attattgaat
     8941 gcctatgcgg tagcaggaac gcctgctgct gagattgcca aaaactgggt ttgggatttt
     9001 ggtttcttta ccattaatcg tattgggtat caggcacagg ttattccagc ccttttagct
     9061 ggtctgtccc ttgcttatct tgaaattttc tggcgtaaac ggattccaga agtggtttca
     9121 atgatttttg tgccattcct ttctttgatt ccagctttga ttttagcgca tacggtattg
     9181 gggccaatcg gttggattat tggtaaaggg atttcctttg ttgtgttagc tggattgact
     9241 ggtcctgtta aatggctatt cggtgctatc tttggtgcct tgtatgctcc gctagttatt
     9301 actggtttac atcacatgac aaatgccatt gatacccaat taattgctga tactgcaact
     9361 cgtacaactg gtttgtggcc aatgattgct ctttcaaata tcgctcaagg gtcagctgtt
     9421 tttgcttact atttaatgaa tcgtcatgaa gaacgtgagg ctgaaatatc gcttcctgca
     9481 gcaatttctg cttaccttgg ggtaactgag cctgccttat ttggggttaa tgttaaatac
     9541 gtttatccct ttgtagccgg aatgattggc tcaggtattg cgggtctctt atcaacaacc
     9601 tttgatgttc aggcaaattc tattggtgtt ggtggcttac caggtttcat ggctatcaat
     9661 gtgaagtata tgattccatt cttcatctgt atggcagtag ccattgtggt accgatgttt
     9721 ttaaccttct ttttccgtaa atcacatatc atgaccaaga cagaagatga ggctaaacta
     9781 gctgagacac ccgtttcgga ggctcctgcg gcaactgctc cacataagac tatgcaagga
     9841 acagttatca ctttaaccag ccctttaacg ggtgaagtta aagcgttgtc tgaagctgtt
     9901 gatcctgtct ttgcacaggg agttatgggc caaggtgttc ttcttcaacc gacagaaggg
     9961 gtgttagtag cgccttgtga tgctgaagta tcggtcttgt tcccaaccaa acacgctatt
    10021 ggtttggtga cggctgaagg tttggaatta ttgatgcata ttggtatgga tacggttaac
    10081 ttagatggtc aaggatttga agctttggtg aagcaaggtg atcaggttaa ggctggacaa
    10141 acattgattc aatttgatat agcagctatt tctgaagctg gatacgccac tgaaatgcct
    10201 cttgtggtga ctaatcaaga tacttttacg gtaactgttg aaggtagttt accgcatcag
    10261 attaaggcta atgataagct agtagtagcg gtgaaaaagt aggtttacta agagaaaacg
    10321 ttcaggaact gagatcagtt cctgaaacta ttttagggag gaaaactcat gacaattgat
    10381 aaaaagaaag tcgtctatca aatttaccca aaatcctata aggacactac tggaaatggt
    10441 gtgggagact tgcgagggat cattgataaa ttgccttact tacaagaact aggaatagat
    10501 atgatttggt tgaacccttt ctaccctagt ccacaacgag acaatggcta tgatgtttca
    10561 gattatacgg cggtcaaccc tgattttggg acgatggctg attttgaaga tttggtaaaa
    10621 gctgctaagg agcatcagat tgagttaatg ctggatatgg ttttgaatca ctgttccaca
    10681 gaccacgagt ggttccaaaa agctttagca ggagaccctt attatcagga tttctttatc
    10741 ttgagagatc agccgactga ttgggtttcc aaatttggtg ggaatgcttg ggcgcctttt
    10801 ggagatacag gcaaatacta cttacacttg tttgatgtga cacaggctga cttgaattgg
    10861 cggaacccac atgttcgtga ggaattggct aaagtggtta atttttggcg agataaagga
    10921 gtgaaggggt tccgttttga tgtgattaac ctgattggga aagatgaaga gctggtggat
    10981 tgtccggtca atgatggtaa gccagcttat acggatcgtc ctattactca cacttatctt
    11041 catgatctca atcaagccag ttttggtcag gatgattcgt ttatgacagt aggggaaatg
    11101 tctgccacga ctattgacaa ctgtctttta tacacggctc ccgaacggga agagttgtcc
    11161 atggctttta atttccacca tctaaaagtt gattatgaga atggtcagaa atggactatt
    11221 atggcttttg attttgcagc gctgcgagac ttattccatg cctggggtga aggcatgagt
    11281 caaggcaatg ggtggaatgc cttgttctac aataaccatg atcaaccacg tgccctgaat
    11341 cgttttgttg atgtaacaca tttccgaaac gaaggtgcaa cgatgttagc ggcttccatc
    11401 catttgtcac gaggaacgcc ttacatttat atgggtgagg agattggcat gcttgatcca
    11461 gattttgata gtatggataa ttatgtggat gtggaaagtc tcaatgctta ttcaagctta
    11521 ctagtctcag gtaaaagtgc agaagaagcc tttgccatta tcaaggctaa gtcaagggac
    11581 aatgccagaa caccaatgca atgggatgct agtgaacatg ctggctttac gactggtaag
    11641 ccttggttag aggttggcaa atcttatcga gacatcaatg tcgaaacaga aaaagaggga
    11701 cgtatttttc ctttctacca acgcttgatt gctttgcgga aggaactccc tattattgct
    11761 gaaggggact atcgggctgc ttttaaagat agtcaggctg tctatgcctt tgaacgccat
    11821 ttaggtgacc agtgtttgct tgttctcaat catttctatg ctgatgaggt cgaactggaa
    11881 ttacctccac gttatcaaca tggacaggtc ttaatcagca actatgagaa agtttctatt
    11941 tgtgaaaaag tgatactgaa accttatcag acacttgcta tcttagctga taactaacta
    12001 aaagcctgag gttaggcctc aggcttttgg tgattgtcac gaaaaaagaa gttttctcat
    12061 atatttattt ttaaactctt attttttcta aataaaaaca attgagacaa gttattttag
    12121 ctaaattttg gtacaatgga aaagattata agtagagttt aagataaaga ttctacaaat
    12181 ttaaaatgat ataaggagat acgaatgaca acttatcaag atgattttta ccaggctgtg
    12241 aatggaaagt gggctgaaac agcagttatt ccagacgaca agcctcgaac aggtggattt
    12301 tcagacttag cagatgaaat tgaggcatta atgctagaca ctacagatgc ttggctagct
    12361 ggagaaaata tccctgatga tgcaatttta gcaaactttg ttaaatttca ccgtttggtg
    12421 gctgactacg ctaaacgtga tgaagttgga gtaagtccaa ttctcccttt aattgaagaa
    12481 tatcagtcct taaaatcttt ttcagaattt gttgctaata tagcgaaata tgaattggca
    12541 ggtttaccaa atgaatttcc ctttagtgtg gcaccagact ttatgaatgc tcagctgaat
    12601 gtgctttggg cagaagcgcc aagcattctg ttgcctgaca cgacttatta tgaagaaggt
    12661 aacgaaaagg ccgaggaatt acgtggtatt tggcgtcagt cgcaagaaaa gcttttacct
    12721 caatttggtt tttcaacaga agaaatcaag gatcttttgg ataaggtaat tgagctagat
    12781 aagcaattgg ccaagtatgt cttgtctcgt gaggaaggct cagaatatgc caaattatac
    12841 catccttatg cttgggctga ctttaccaaa ctagctccag agcttccttt ggatagcatt
    12901 tttgaaaaga ttttaggcca agtacctgac aaggttattg tccctgaaga acgtttttgg
    12961 acagaatttg cagccactta ctactctgaa gctaactggg atttactcaa agctaatttg
    13021 attgtggatg cggcgaatgc ttacaatgct tacttgaccg atgagattcg tgtacagtct
    13081 ggtacctatg cgcgtgcttt atctggaacg cctcaagcca tggataaaca aaaagcagcc
    13141 ttttatttgg ctcaaggacc gtttaaccaa gcgcttggct tgtggtatgc tggtcaaaaa
    13201 ttctccccag aagctaaggc tgatgtggaa agcaaggtgg cacgcatgat tgaggtttat
    13261 aagtctcgtc tagaaacggc tgattggtta gcaccagcca cacgtgaaaa agccattact
    13321 aaattaaatg tcatcacgcc acatattggt tatcccgaaa aattaccaga aacctatgcc
    13381 aaaaaagtga tagatgagac tttgtccttg gttgaaaatg ctcaaaactt ggcaaaaatc
    13441 acgattgctc acacttggag taaatggaac aagccagttg atcgtagtga atggcatatg
    13501 ccagcccact tggtcaatgc ttattatgat cctcagcaaa atcagattgt cttccctgcg
    13561 gcaattttac aggcaccgtt ttattcttta gatcagagtt cttcagccaa ttatggagga
    13621 attggtgcag tcattgcgca tgagatttca catgcctttg acaccaacgg tgcttccttt
    13681 gatgaacatg gtagcctaaa tgattggtgg acacaagaag actatgctgc ctttaaagag
    13741 cgtacagata agattgtggc gcagtttgac ggcttagagt cacatggtgc taaggtcaat
    13801 ggtaaattga cagtttcaga aaacgtcgct gatctaggtg gggtagcttg tgctttagaa
    13861 gcggcacaat cagaagaaga cttctcagcc cgtgacttct ttattaactt tgcgacgatt
    13921 tggcgtatga aggcccgtga ggaatacatg caaatgctag ctagcattga tgttcatgcc
    13981 ccgggtgaac tgcgaacaaa tatcacctta accaactttg atgctttcca tgagaccttt
    14041 gatattaaag aaggcgatgc tatgtggaga gctccgaaag accgtgtgat tatttggtaa
    14101 ttaggtagtt gataaacctt caaatgcctg tgattataaa aatgactgat tctgtgaaac
    14161 acaggatcag ttttttgctt ccttattggt gtccgttttg atacaacaaa aagacaacct
    14221 tcagggaaag aaggttgcct tttttagact tatcagaaat aagtgattag ttgttaaggg
    14281 cagcagccat agtagctgca acttctgatt caaagtcgtt agcttttttc tcgatacctt
    14341 caccaacttc aaaacgtgca aaagcaatcg ctttagcgtt tactgagtca aggtaagctt
    14401 caacagtttt gctgtcgtcc atgatgtaaa cttgtgcaag aagagtgtaa gcttggtcaa
    14461 ctttagtgtt gtcaagcatg aaacggtcca ttttacctgg gatgattttg tcccagatct
    14521 tttctggttt gccttcagca gcaagttcag ctttgatgtc tgcttcagca gcagtaatca
    14581 cgtcgtctga taattgagct tttgaaccgt atttcaagaa tggaagtgct ggtttgtcaa
    14641 ccattgcacg cgattcgttg tcaagttcga tagcgtggtt caattgagca agttcatctt
    14701 tgatgaattg tgcatcaagc tcagtgtatg aaagaacagt tggtttcatt gcagcgatat
    14761 gcattgatac ttgtttagca agagcatcgt cgccgccttc gacaactgag ataaccccga
    14821 tacggccacc attatgttgg taagcaccga agtgttgctc atctgttttt tcaatcaaag
    14881 caaaacgacg gaatgagatt ttttctccga tggtagcagt tgcattaacg taagcttcag
    14941 caagagtttc acctgaaggc ataacaagtg caagtgcttc atcgttgtta gctggtttgc
    15001 cttcagcgat aactttagca gttgcgttta ccaattcaac gaattgagca tttttagcaa
    15061 caaagtctgt ttcagcgtta acttcaacaa cagcagcaac gttaccatga acgtaaacgc
    15121 ctgttaaacc ttcagcggca acacggtcag cttttttagc tgctttagcc attccttttt
    15181 cacgaagaag ttcaacggct ttgtccatgt caccatctgt ttcaacaagt gcttttttag
    15241 cgtccataac gccagcacca gatttttcac gtaattcttt tacaagctta gctgtaattt
    15301 ctgccatgtg tagtatcctc caaatgatat ttgttttggt ttcaaaaaac gagacagagc
    15361 ggtttgcttt ctgccccgtt tggttttcga ttgttaaaga caaacaaagt ttgccataag
    15421 agttaggaac tctgtgctaa ttaagcgttg tcgccttcga caacttcaac gatttcttcg
    15481 attgaatctg cttgagtgtc agcttcaaaa gcaacgtctg catcttcacc ttgacggcct
    15541 tcgataatag catcagctaa tttagcagtg attaatttaa cggcgcggat agcgtcatcg
    15601 ttagctggaa tgatgatatc gatatcatct ggatcagcgt ttgtatcaac catcgctacg
    15661 actgggatac caagtttttt agcttcttta acagcaattt gttctttatg tgggtcaaca
    15721 acatacatca cgtctgggat acgaggcata tcttcgatac cgcccaagaa tttttcaaga
    15781 cgagcgcgtt gtttgttaag aagtgcaact tctttcttag gaagaacgtc aaaggttcct
    15841 tcttcttcca tacgtttgat ttctttcaaa cgagcgatac gtttttggat agttccccag
    15901 ttggtaagcg ttccacccaa ccaacggtgg ttgatgaagt attggcctgc acgcgttgct
    15961 tcgtcagcaa ctgcttcagc agcttgtttt ttagtaccaa cgaacaagat gacagcatcg
    16021 tttgctgcag catcacgaac aaattcgtaa gcttggtcag ctaattttac agtttgttga
    16081 agatcgataa cgtggatacc gttacgctct gtgaagatgt atttagccat cttagggttc
    16141 cagcgacgag tttggtgacc aaagtgaaca ccagcctcaa gaagttgttt cattgaaatt
    16201 actgccatga gtagtttctc ctttataaaa tgttttttcc tcttccagac ttcgacttgc
    16261 aggctaacct agcggcaaca agcccacaat tggtctagaa tgagtatttg ccgtctacac
    16321 gaccctacta tattatcaaa aaaagaggtt aaaagcaagg agaaatacta tggattcctt
    16381 tatttttgag atgactagct tctttgttta ttggtaagtg ttaagacaag cttttgctca
    16441 ttttgggtga cacttgccaa atcgttttat ttaagatata gtgaatttga ctaatttttg
    16501 gaggcgtttt catgacgaag ggtattcgat ttcaattgct tggcagtccc cacatttttc
    16561 ttgatgacaa agaacaattt tttgcctttg ccaaagcaaa tgctctcctt tattacttag
    16621 tggttaatgg atctgttagc cgcgaggtgg cggcgagtct actttgggaa aataagaaca
    16681 tgcaaacagc gaaaaagaat ttacgaaacg ctatctacca ggtcaataaa gtcttgcaag
    16741 ctgatgtgat tatttgtccc aatcgcaacc tgctggtttt gaataaaaca cttgatatca
    16801 aaacagatat taaccttttt ctggctgatc cgctagctca cttagaactc taccaagggg
    16861 agtttttgca gggcttttac cttaaaagtg gtgaggaatt tgatctttgg gtttcaaaaa
    16921 tgcgtatgca gtatgaacag gtatacctaa aagcgtgtta ccaaaaaatt gaagaaaagc
    16981 tctctttaga tgccattgaa gatgtcgagg aacatttaaa acagcttatt gaacgtgatg
    17041 aatttgaaga gaaaaattat cagctcttga tgaggcttta tcagcagggg aattgtcctg
    17101 gtaaggtcat cgaaacttat tatcagttgg ctaatgtgtt ggataaggag ctagggattc
    17161 agccaagttt gcaaagccaa cagatttatc aggaagtggt cgctaaagat cgtaatgaac
    17221 gcaaaatcaa gcattttttg cgcaacagta atcatttttt ggggcggatt gatgagatta
    17281 agcagctgga aaactatttt gccaactgtt tggcctgcca agaggtagga gctctgctct
    17341 taattggtga tacagggatt gggaaacgaa ccctagccag acaggtctta gccaatcaaa
    17401 cccaaacgtt tcaaattgtc acagctaaat gttttcgtga agaggctatg gattccttat
    17461 tgccttggcg taatatctta gatggcctgg gagatttggt gattcaaaac cgcttattga
    17521 ctaccaaagc ttggaaggct gctcttaaac gctgttttcc tgtggcaacc atttttcaag
    17581 aagataacaa ccaacccttt atcaaggacc acaccagctt gttggtttcc tttattgttg
    17641 atattttaca acatttggca gaaatcaagg cgctggtaat ccttattgag gattgtcact
    17701 ggatggatga ggatagtttg accttgttgc aacgggtcat gaatcaattg gtccactatc
    17761 cgattgcttt tgtcttgacc aagcatctag gaacaactcc tgagctcggt ctttgtttga
    17821 atgctttgat gagtcagggg cgtttagaaa gcatttgttt ggagcctttt aatcggcaag
    17881 aaagtttggc ttatattaac agtcaactgg gtagtcagcc agtgacggca gaagaaatgg
    17941 agcacctcta tcaagccagc caaggcaacc ctttcttttt gtcagaatac actcaggccc
    18001 tactgcgtca cgaaaaattt gtgcctttaa cgcctgccat taaggctaag ttgggtctta
    18061 aactagctaa tctaagtagt cgtgatgacg cattgttaaa ctatttgtct tgttgtcgga
    18121 ggcctatccc tctaaatacc ctcgctcaat tgatgttact gcctttagaa gaagtgatcg
    18181 agatggtgga taatctgggg cactactata ttttggtaga agaaagcgta ggagaggaag
    18241 tgttgatttc atttcgtcag cgaattattc aactctatag ttatgaccgt ttatctttgt
    18301 caaaaaggcg tttattgcac ggacaaattg ccaaacggtt agaagattta ctgcctattt
    18361 tgacaccaag ccctcactta ttagatgaca ttgcttacca ttatcaggaa tcacggcagg
    18421 tgattaaggc tttggaatac aaccttaact atctagatgc taccttgcca tttcagcatg
    18481 agctgtttcc catttattca aagagtattg gctccttgga aaagtcagat cgtgaccatc
    18541 aacgcttaat ggaagagcag tttgataaga ttcggcaaag cattgcggat ttggaactga
    18601 cctatgataa taaccgtgat ttccagcagt tgcttattcg tttttcttac cttgaaggcc
    18661 gttatgatat tcgaacaggg aggtatcaag aagggattaa acatattcaa aaggtcatcg
    18721 ctttggcaac cgagctaaaa cagccctcct tcttgctaga aggctatcgc cagttaattc
    18781 attactgtat ccaagtggaa aacaagccag aaatgcgtta ttacactagt ctttcattgg
    18841 aggcagcggt tgctgctaat cattttgagg ccattgcgat tagtttgcgg ttaaacggtc
    18901 tttatcattt gattattggg gagttaaatg aggcagagcg tctgcttcaa cagtcgattg
    18961 acttctttaa ggtgacgcca ggcttgcaag ctaactatgc gattcagatt gctgctgcct
    19021 tagattattt gggggagatt gcccagattc gctatcagtt tgaaaaggcc gttacttacc
    19081 aaaaacaagc cattgccttg accgaaaaca agccagctga gttatcggtg agtatttttt
    19141 atattggatt agggatttcc tacttttatt tagctgattt tgaacaagct gagcaaatct
    19201 tgagtttggc taaggaagct ttggtcaatc atagttatcc ttggaaagaa acgcaacttg
    19261 aaatttacct ggccatgatt caatggaaaa agggtaatta tcagccagcc ttgaccctac
    19321 ttgattacag agaaaccttg atgtctaggt atcgcaatcc gcgtgataag ggcttggttt
    19381 tctatttgat ggctgtggtc aagtaccaat tgatatttca aggagctacc ctaagtcagc
    19441 aggaaaagga aatggcagac cacctgttgt cagaatcctt tgagtattat tatgagattg
    19501 ctagtactaa cctcaaccct taccgagatt gtcatttggt gagtgagttg aacgatttgc
    19561 gtcaacaatt atctgctaaa agctaaggaa aaccctctga ttcacatcag agggttttag
    19621 ctatgttgtg ccataatctg tacgaggtaa aagataaagg tggctgctaa attggcggtg
    19681 tggttatcaa tatcgtgtgg tggtgaaacc tcaaccacat caaagccaac taattttcta
    19741 ctagccgcaa tgtgttgcaa aactaagacg gcaagatttg ggtcaacacc gagggactgg
    19801 atagcactaa ccccaggtgc agcaccaact gagaaacaat ccatgtcgat agtcaggtag
    19861 accctttctt gcccttctaa gaaacggtca atggctcggc agaccttttg atgccccatt
    19921 tggtagatgt cttgaccagt caaaaattga atgcccttgg attttgccac aaagtcaaat
    19981 aggaaaaggt tgttattatg ttcttgaatg cctaaaacga agtatttaaa gaggcgtttg
    20041 tcagcaaccg catcgtcaaa catttgtcga aagcctgtcc ctgaattagg gcctgtttgg
    20101 tcgtaaggcc ttaaatcaaa gtgggcgtcc atattgatga cagctaggtc atcacttggg
    20161 gataggcttt ggcgtaggcc taagtagtgg ccgtaggcgg tttcatggcc acctcctaag
    20221 acgatgggtt tgagattgag gtcacacatc cgtttgatgg ctttgcttaa actgttttgc
    20281 agttgttcca aagagcgatt ggggccgtca atgttaccca catcgtaaac cataacttgg
    20341 tttcctaaat gccaagggaa tttggcgagc tgggttcgta tggcagctgg actttcgacc
    20401 gctccgacac gaccattatt gatataaacc cccttatcac ttttaaagcc aatcaaggca
    20461 aaatgtgtcc cttcaaatgg ggttagtgag ctgtcgttaa ggtcaaggaa agtcatgacc
    20521 atgccccatt tggcagtata taagtcatcg tcgatcccac catgataata gctagtggtg
    20581 gatgggtagt aatcttctag catgcgcgtc atctccttta ggattatgat agcaaaataa
    20641 aacttacagt caacactttc ttggcctttg tcactggttt ttaggaatag cagagcaata
    20701 aaatcgtctg cttttggtcc cggttagtta gtctaaagag gtcatgacct ctgccacagc
    20761 ccctctagtt aaagaagtac cttattcact aaaattggat actcaactca actgtctgct
    20821 caaccgcttc gaggaagctt gggtcttcaa tgactgttga tgccttgttt agttcatcgt
    20881 agatttcgat gtgtttatcg tgttcgataa agttgacttc cttgcggaag agatcgtagg
    20941 caaccttagt ccctttacct agttcatgat tttcagattt gagatcaagg gcttggcagg
    21001 ctgccatgat ttcagtagcc acgatgcggc gagaattttt aaggatttca aaggccttgc
    21061 gagcagcggt ggtgcccatg ctgacaaagt cttcttggtt ctcacaagat gggatagaat
    21121 ccacactggc tggatgtgcc aaaaccttgt tttcagaagc aagagaggca caggcgtact
    21181 gggtaatcat aaagcctgaa ttgagacctg ggtatttgac aaggaaggat ggcaatttgc
    21241 tgagctggct attgaccaaa cgttccacgc ggcgttcaga aacatttcca atttcagaaa
    21301 tggcgatgcc taagaagtca aatggctgtg ccattggttc tccgtggaag ttacctcctg
    21361 aaataacgtg gccatcttta cagataattg gattatctgt gacagaattg atttcaatgt
    21421 caactttgga tttgacatag gcgatactgt ctttgctagc cccatgaatt tgagggatgc
    21481 agcgcaaggt gtaagggtct tgcacacgag attgagtagc tacggttgtg ttttggctac
    21541 cttctaggag gtttcggata ttgcgggctg ttgccaactg gccgctttga gggcgaatgg
    21601 tgtgaaggtt ttcttcaaat ggactagtaa tcccgttatg cacttcaaga gatagggcac
    21661 cagctaggtc tgacagtttc aataattgaa tggcgtcata ggttgcaagg gcaccgattg
    21721 cagtgagaac agttgttccg ttgataaggg cgagtccttc tttagcggct aaagaaatct
    21781 tgtcaatacc agctttatca agagcttctt gaccagaaag aagctctcct ttgtagtaag
    21841 ctttccctag accaagcata ggaagcacca tgtgagcaag cggcgccaaa tctcctgaag
    21901 cccctagaga ccctttttca ggaatgtaag gatgaacccc tttattgagc agttccaaca
    21961 gtttttcaat ggtggataga cgaataccag aatacccttt gacgagagag ttgatacgga
    22021 tcagcatgat agctctcacg gcatcttctg gcaatgggtc accaaatcca ctagcatggg
    22081 tacgaatcaa attttcttgg agttgaactg tatcttctgg tgagatgctt acgttacaaa
    22141 gggatccaaa accggtggtc accccgtaaa ccacccgttt ttcactgaca atgtcatcaa
    22201 caattttacg agaggcattc acagcttcaa tagcactatc atcaatgcga caggctacgc
    22261 cttggcgagc aatcgcaatc acgtcttcga tagtaaggct ttcgccatct aaattaatca
    22321 ctcttgtcat agtttttctc ctagatttgt tccttagggg gcatttggtc catttggtcc
    22381 atttggtggt tacgtccgtg cataaggtag tacacactac ttgcaatgat gacaccaact
    22441 gcaccataaa caaagttcat tgggttgtca ccccaaatca taactaaact aacgataact
    22501 gcaagaattg ggataatagg gccaaatggt actcggaaga tcacattagc atcgggatcg
    22561 tccttccgta atttcataac ggctagtgct gttggaatgt attggaagaa gcggaaaaca
    22621 acactgagtt ttgctaagtt ttcaaatgag ccagtgagta ggagtataat agcaattgct
    22681 cctgaaacca agatagcaac gagtggcgcg ccattttgat tttgcttggc aatagcagct
    22741 ggtaagagcc cttcatcagc aatggcagca ccgtaacgtg gcaccatgat ggattctccc
    22801 atgttaagac ctgtaatgga aattaaagca ccgattgaga ccatccaagc gccagcaggg
    22861 cctatcattt taacaaaggc atcttgaaca ggtgcattgg tcatcatgat ttgagagcca
    22921 agcatggcaa tggttccacc gataatcagc atatataaga cagagacgat actgattgat
    22981 cctaaaagag cacgcggtac atttttttca gggtcacgca tttccccagc gacaatagag
    23041 agggtttcaa aaccgataaa gccatagaag atataaacag cagtattgga gatagcccct
    23101 aagaggttag tccctggttc caactgaaca aatggggtaa agttaggaag cccgtttttg
    23161 atgaagaaaa gggtacagac acaaaaggca acgattggaa ttaacttagc aatggtggct
    23221 gtgatggtga caattttaga ggttttcaaa ccagcgatat tcatcaaaga tagtaagatg
    23281 attaacccaa tactaagtgg aatgtgccaa ccttcaaagg cagggaaagt aatgataaac
    23341 attctggcaa acccagctgc catggctgcc caagcgaaga tagtaacggt ccaaccaagg
    23401 aagccaacgt taaagccaat aaaatcacca aaagctcgtt tggaatattg gaaggctccg
    23461 ccgtttttcc caaaataacc agagacttct gcaaaacaaa ctgccaacat gatggtcaaa
    23521 atagctgttc caaacataac agcgatggat gcagggccaa ggcccttgta aatggcccta
    23581 ggtaagagaa aaataccaga gccgataacg gcattgatcc cgtaaagagt ggcaccgctc
    23641 aagctaaact ttgcctgttc tctttcttgt tcgttcatgt gatttgacgc cataataatg
    23701 ctctcctttt tgtttgcaaa ttgcgttcaa atataatgga taaggtcgct aggaaatgag
    23761 gagatagtcg gtttaggagg gtccttcttg cacctaacga tagtgatgag ctattggtta
    23821 gcgatgagaa ataggtagcc ttttgtgatg atgtgtagtg atttcattgg agaagaacag
    23881 gcatgagtag tgtgatgcct atctttatcc cactaagtct tataccataa gcctgcccaa
    23941 acagctactg gagtttgggc ggggcttgtt tgattggggc aaacttttag gtctgaaagg
    24001 ctggcctcct gctcgattac caacaagtga ttggcttcaa gctcttgatt cgcctgattg
    24061 gtcacagaat aagtcagttt gcttagggca taaagcagtt gacagtccgc tttaggtgtc
    24121 tcaaatagtg tgtcagacca gacgggtaat aattgccctt ggtattggtc atcatacatt
    24181 aaattgatgt cttggcagat tccacgactg acgattctgg tatcgccttc aaacgcatag
    24241 ggttcaaaag gagttaggga aatctcttta gcatgactca aatcactcaa tgtgatgggc
    24301 ttgtctaggg tcattaggat cctgtgatag ccatcaagta aggtaaaggt tgtctgtcgt
    24361 agggccacag ttgactttga gaggcgataa gagaattctc tctttttgta atctccatct
    24421 tcgggataaa ggaacaattg attggtttca ccgccagacc agtcagtttg agtgtaatct
    24481 gctggcgttt tgaccattac ggttgtcatc tgttctctcc ttgtttccaa ttagaatagt
    24541 cctgtgatgt tgccctcctc gtcaatatca attgtttcgc tggcaggtac ttttggaagg
    24601 ccaggcatgg tcatgatagc acccgtcaga gcaacgataa atcctgctcc tgcggacact
    24661 ttaaggttgc taatagtcac tataaagtca gttggtgcgc caagtttttt ggcatcgtct
    24721 gagaaggaat actgggtttt ggccatgcaa attgggtagt tgccaaagcc gaggcgttct
    24781 aattctgcca gttcacgttt ggctgtgggg gtcaatttga tacccttacc accgtaaacc
    24841 ttggtaacga ttttagtcag tttggtttca atgctatcgt cttcattgta aacaaagcgg
    24901 aattgattgt cttgttctgc caatgctact actttttcag ccagttcacg gccaccagct
    24961 ccgccattcg cccaaacgtc agaaatcaca acatcaacgc cacgtttgtc gcaggcatca
    25021 tagacagctt gtaattcggc atcggtatca agcgggaatt tattgatcgc cacgacaact
    25081 ggaagaccat agacgtcttg gatattagcc aaatgtttgt caaggttagg taaaccatcc
    25141 acaacggcct gaacattttc agtagccagg tctgcttttg gcacaccccc atgcatttta
    25201 agggcacgaa tagtggctac taggacaacg gctgctggac gaaggcctga catgcggcat
    25261 ttgatgtcaa tgaatttttc agctccaagg tcagcaccaa atccagcttc ggtaacggca
    25321 taatcgccat atttcaaggc tagtttggtg gctaggacac tattacagcc atgggcgata
    25381 ttagcaaatg ggccaccgtg aatgagggct ggtgtgtgtt ccagggtttg cacgagatta
    25441 ggatgaatcg catccttgag cagtgctgct agggcaccac cagctttcaa gtctttagct
    25501 gttacaggtt caccttggaa gttgtaaccg atgataattt tttcaaggtg ggctttgagg
    25561 tcagaaatat tttcggatag gcacaggatt gccatgattt cagaggcgac ggtaatgtca
    25621 taaccatctt cacgagggac cccgttgacc ttaccttgca agccgtcaac aatatgacga
    25681 agctggcggt cattcatatc caccacacgt ttccaagtga tacgtctaga atcaatgcct
    25741 aggctattgc catggtgaat gtggttatca atcaaggcag ctaataagtt gttggcgaca
    25801 ccgatggcat gaaagtcccc tgtaaagtga aggttgatgt cttccattgg gacaacttgc
    25861 gcgtggccac cgccagcagc tcctccctta accccaaaaa caggaccaag agaaggttca
    25921 cgaagggcaa taactgcttt ttttccaatg gcagaaagag catctaccaa tccaacagaa
    25981 gtggtggttt tgccttcacc agctggtgtt ggtgagatag cagtgacaag aatgagtttg
    26041 ccatcaggtt tgttttttaa ggcgaccagt tgacgggcat caatttttgc cttgtactta
    26101 ccatagagac agagcgcttc cttgtcgatc cctaattgat cggcaacctt actgataggt
    26161 tccatagtga cagagttggc tatttcaata tctgataaaa ccatagttgc tcctttactt
    26221 gttaaacaat atcgagaatt ttcgtgtaga tgtcatctgc caaatgacag cccttgtcta
    26281 ataaggcttg tcctttttgg cgatagtcgg taacaaagtc ttcatctttg atgccagaca
    26341 gattaatcaa aacattcaac caagcgcctt gtaaacctgc ttttaagttt aaagcagcaa
    26401 ctcctaagtc actagcagca tttgtattag acttaccgac agctgttgca gtgatctcaa
    26461 gtgcttcgac catgagggtc atcatctcaa aaggtgattg tgcagctgtt ttcaaagtct
    26521 tttgcatggc agttcgtctg gcagccttgt cttcgtcagt ctcttttggc atgtcgaaaa
    26581 cgtcagaaac caggttgaag gcttcggtgt ctttgtcaat ggcatctaat aagtcctgtt
    26641 gcaagcgact acttttggta tgaaggtctt caatgatatc ttgataatca gcatactttt
    26701 tcttaccaag ggtcaattca cagaccatct tggtcaagga aatgccatta gcgccagaga
    26761 gagcagcagc agaaccacca cccggagcag gggcatctga gccaaggact ttagcgaaat
    26821 ctgttaagct taaatcaact aatcccataa gacaccccct agcctagcaa atggttttca
    26881 agaatctgtt tatggtagtc aaagtcctca acttgcaagt agtattcagc cacatcgatt
    26941 aaggctttag ctggcgctaa gcctatgatt tcagaaccaa taacattcac accgtagcga
    27001 cgcgcttcaa atttgatggt ttcaaaagta cggtaaagag aacatttttc aaagttaacc
    27061 atgttcatgg aaacttgggc aatatgacgg tcttctaaca tgacaccgat agccttacaa
    27121 tatttgtagc caccacctga accgcggata attttcgcaa ttttatgagc aatgtcgata
    27181 ttgtcagtat ccaaattaac attgaaagca accaatggca tacgagcacc aacggcagtt
    27241 atcccagcag ttgggtgaat cttacgatct ccgtaatcag gtgcccaatc ctcttccaac
    27301 agtttttctg gcatgccttc gaattgtcct ttacggactt tggccaggtt ttgacgttct
    27361 gggcgtgtgg cagaatcttc ataaaggaag attgggattc caagttcacg gttaatccgt
    27421 tctgcgactt gtttggaaat ctcaacacat tcttgtgtag tgatgtcttt gatcggaacg
    27481 aatgggcaga catcggttgc tcccatacga gggtgttcac catgatgttt ggtcatatca
    27541 atgttttcag aagcgtattt caccagttgg aaagctgctt cttgaataga ctggtcatct
    27601 ccaaccaagg taaacacgct ccggttgtgg ctcgcatcag aagagtagtc gagaagggtc
    27661 actccaggaa tacttttggc cgtcgctacc aaaccatcga taacagcctg attttggcct
    27721 tctgagaagt tgggaataca ttcaacaatt ttcgccatgt taatctcctt ttatgtcatt
    27781 gagttactca ttaagggaat aggttaccta ctttagataa cgcttacatt tttagctagc
    27841 agttattagt gaaataattg atctaccgct gaagtcacaa ggtcatcatc agccaagtat
    27901 gggatagtga tgtgatcagt acctgcatgg agacggttgt attcaatagc ggtttcaata
    27961 gcgtgctcat tgcgagccca attgcgacga gcaacaccac ccatggtgtc ccaagcaata
    28021 gcagatttaa taatctcatc aatgcgttcg ctgccatcta gaacaagtcc aaagccgccg
    28081 ttaatggctt taccgatacc agttccgcca ccgttatgaa gagccactaa actcatacca
    28141 cgcgcagcgt taccagcgta acattgaact gccatatcac aggtgacatt ggaaccgtct
    28201 ttaatgtttg aggtttcacg gaatggtgag tcagtaccag acacgtcatg gtggtcacgg
    28261 ccaatcatga caggtccaat cttaccttct cggaccaatt cattaaattt aagggcgata
    28321 gtcacacgac caatacagtc ttggtaaagg atacgggctt gtgtgccgac gaccaattga
    28381 tttttctcag catcacgaat ccagttatag ttatcacggt cttgatagcg gcggtcagga
    28441 tcgatagctt ccatggcagc tttgtcagta gccaccaagt cttcgtgttt accactcaag
    28501 cagacccaac ggaaaggtcc atagccatag tcaaaaagca taggtcccat gatatcttcc
    28561 acataggatg gccagataaa gccgtctttg tcgttacgac cattcttaga aatttctgta
    28621 ataccagagt cgtaaacaga cttcataaag gcattgccgt agtcaaagaa ataggtgcca
    28681 ttttcagtta acgtcttaat agcttcaaaa tgccgtgcca aggtatcatc aaccatttgg
    28741 tggaaggtat ccttgtcttc tgccaggagc cgggttcttt cgtcaaagct aatacctact
    28801 gggcagtagc caccgtcata aacgttgtga caagaggttt ggtcagacaa aagatcaaca
    28861 tgaatctgct tgtcattgac gtactctaaa aggtcaacaa tattaccatg gtaagcaatc
    28921 gaagtggact ccttagcatc tatggctttt cgggctaatt gcagagcttc ttcagggctc
    28981 tcagcaattt ggctaaccca gccttgcgaa tgacgggttt caatccgaga ttggtcaact
    29041 tcagcaataa tggcaactga tttagcaatt tcagcagcct taccttgtgc cccactcatg
    29101 cctcctaaac cagatgagat aaagagttta ccggtcaaat caccatcgtc agccactcca
    29161 agtttgagac gaccagcatt taagagagta ttaaatgttc catgaacaat cccttgtggg
    29221 ccaatataca tccaaccacc tgcggtcatt tgaccatagt tggtgacacc catctcttcg
    29281 gcgatttccc agtctttcat gttgtcgtat tcacccacca aaaggccatt agtaataatc
    29341 acacgaggcg cttcaggttt ggatttgaaa agaccaactg gatgaccaga ctcaaccacc
    29401 aaggtttgtt catcagtcat gacctctagg tattttttaa tcaaacaata ttgcatccag
    29461 ttggcacaaa cagaaccagt ttctccataa gtgactagtt cgtaagggta caaggcaatt
    29521 tcaaaactca agttattgtc aatcatgacc tgcatggcct tggcagctgt acaatttccc
    29581 ttgtactcgt caatgggttt gccgtaaatg cggtcttttg gacgccatct gtaaccatag
    29641 atgcgtcccc ttgttttgag ttcttccaaa aattctggaa tgacttcttc gtggaacttc
    29701 gtaggtacat agcgtagggc attttttaag gcaatttcgg tctgagcctg ggtcaatcga
    29761 aaacctctgt ctggtgatct tcggatacct tctttgaaca cagtcttttc cggtaaaaca
    29821 tcgtctaact taacagtcat agcggcagct atgtcagttt cactgtaaaa tgacatagaa
    29881 aactcctcct caactccttt ttattgtcga gattagtcta acttagtcta gtctataaaa
    29941 agtcaaccac gctttgaaat gcgaaaaaag tctaaaaaaa aatcaaaacc tcattttttg
    30001 actaaaattt gacgcttaat cagtacactt gaggtatgac agataaagtc agtcagaggt
    30061 taattgttgt taccaaagtt gcagagatcg caactattga gtgggtgagg ggggctagta
    30121 atggctatta atcagttgac aaacgatgtt aaaaaaggag gtttttatgg ttgctgatgt
    30181 cttattaaca cattttaatc aactattttg tctaaatgat ccaggtcatc ctttaactgg
    30241 tcaagaaatg aaaaaagcca ctatcgttga agatggctat atagccatca aagacggcct
    30301 cattgtggct cttggttctg gtgaaccaga tgctgagctt gtcggtccac agactattat
    30361 gcgttcttat aaaggtaaaa ttgcaacgcc tggtattatt gactgtcata cccatttggt
    30421 ctatggtggc agtcgtgaac atgaatttgc caagaaatta gcaggggtgt cttacttgga
    30481 tattttagct caaggtggtg gtattttaag cacggtgagg gccactcggt cagccagctt
    30541 tgacaacctt tatcaaaaat ccaagagatt gctagactac atgttgcttc atggagtgac
    30601 tactgtcgaa gcgaaaagtg gctacggcct tgattgggaa acagaaaaac gccaactgga
    30661 tgttgttgct gctttagaaa aagaccatcc tattgatttg gtgtctacgt ttatggcagc
    30721 ccatgcgatt cctgaagaat acaaggggaa tcctaaggct tatctcgatg tgattatcaa
    30781 ggatatgctt cctgttgtta aagaggaaaa tctggcagaa ttttgtgata ttttctgtga
    30841 aaaaaatgtt tttacagctg atgagtcccg ctatctgtta agcaaagcca aagaaatggg
    30901 cttcaagctt cgtattcacg cagatgaaat tgcgtctata ggcggagttg atgtcgcagc
    30961 agagctcagc gcagttagtg cagagcattt gatgatgata acaaatgatg atatcgctaa
    31021 gttgattggt gctggtgtta ttggtaattt gcttccagcc accaccttta gtttgatgga
    31081 agacacttat gcccctgctc gcaaaatgat cgatgctggc atggccatca ccctctcaac
    31141 agatagtaat ccaggcagtt gcccgactgc taacatgcag tttgtgatgc aattaggttg
    31201 ttttatgtta cgtttaacac cgattgaagt cttaaatgct gttaccatta acgcggccta
    31261 ctctgtcaat cgtcaggaga gagttggtag tttgacagtt ggtaaagaag cagatattgc
    31321 catttttgat gccccaaata ttgattaccc attttatttc tttgccacca acttgattca
    31381 ccaagtctat aaaaaaggac aactcacggt tgatcgaggt cgtattcttt aaaaaatttc
    31441 aaaaagaagc tttgagcgtt agctcaaaac ttcttttaaa tatgctattt tattgacgaa
    31501 tcaagtagtc aaaggcaccg atggcagcag tagcaccaga ccccatggaa ataatgattt
    31561 gtttataagc tgaatcagta cagtccccag cagcaaagat gccgggaata ttggttgaac
    31621 catgtttatc cacaatgatt tctccgcggt cggttaggtt gacaccacta tctttgagcc
    31681 aagctgtgtt tggaacaaga ccaatttgaa caaagacccc ttcaaggtca aggtgtttgt
    31741 cttcaccgct atcacgttca gtgtagttga gaccagtaac atgatcgtca ccaacaatgt
    31801 ctttagtagc aacatttttg ataatagtca tgttagcagt atcagctgcg cggtcttgaa
    31861 gcactttgtc agctttgagc tcaggcaaga attctaacac gtaaacgtgt ttagcaagac
    31921 cagccaagtc aagggccgct tctaaaccgg agttaccacc accgataaca gcaacatctt
    31981 tgccttcaaa gagtgggcca tcacaatgag gacagtaagt caccccttta ttacggaatt
    32041 catcttcacc aggaacatta atgttacgcc atttggcccc aagagctaag atagcagttt
    32101 tggcttgtaa aaccgcacca ttagctagag taacctcgat gttttctttt ttctcaatag
    32161 aagtagctag ttgtgctttg ataatatcaa catcataaga cttagtatgg gcctccactt
    32221 cggccattaa ttttggtcct tcagtgtaaa gggtaccaat catgttttcg atgccgaccg
    32281 tttccatgac ctgaccacca aaggtttcag caagtaaacc tgtttttagt cctttacgag
    32341 ctgcatagat agcagcgcta ttgcccgcag ggccaccacc aataacaagg acatcataga
    32401 ggcctttatc agcaaaggct tcctcagaaa gtgggccagc gatttgttct aagagttgct
    32461 caatggtagc acgaccagaa gtgaattctt ccccgtctaa aaagacagta gggacagaca
    32521 taatgccttt ggctttcact tcatcttgga acatgccgcc ttctaccata gtgtgtgaaa
    32581 tcttgtcgtt caagacggac ataatgttta aagcttgaac aacatctggg cagttatggc
    32641 aggttaagct gacataagtt tcaaaatgca acggacggtc aatggccttg atgcgatcaa
    32701 taacatcttg atccactttt ggagcacgtc cagatacttg caagagagca agaataaagg
    32761 acgtcaattc gtggcctaaa ggaagaccag caaagacaac cccactatcg tgaccttttt
    32821 tcgcaacctt aaagcttggt tgtcggtcta aagtgatgtt ttcaatagaa atacgctcag
    32881 acatagcagc tatttcttcc acaaagtctt tgactttttg agactgctca ttgtcaccaa
    32941 gggaaacttg caaaacaaga tcagcttcta acagggtgag gtattgggca agttgttctt
    33001 taatatcagg acttaatgcc atagctttcc tcctaaaatt tattaaattt taccaactaa
    33061 atcaagactt ggtgtcaatg tttcagcgcc ttctttccat ttagctggac aaacttcacc
    33121 tggatgttta cggacgtatt gggcagcgtg aattttatca atcaaggtgc tagcgtcacg
    33181 tccaatacca tcagcattaa tttccatcat ttggataata ccatctgggt caacgataaa
    33241 tgttccacgt tgagcaagtc cgtcttcgcc aagcacttca aaggcttgtg aaataaggtg
    33301 tgaagggtca ccaatcatag ggtatgtgat agtgccaacc acatctgaat catcatgcca
    33361 agctttatga acaaaatgag tatcagtaga gacagaataa acttctacac caagagattt
    33421 cagtgtttcg tattgctctt gaaggtcacc gagttcagtt gggcaaacaa atgaaaagtc
    33481 tgctgggtag aaacaaaaaa ctgcccattt tcctttaacg tcttcatttg taacagtgat
    33541 gaattttcca tcgtgataag cttgagctga aaattcagca atttcttttc caattagaga
    33601 catatagttg tcctcctttt ttatagtttt atacttgtat tataaaagaa caacaagatt
    33661 atgtctactc agaaaccctt gattttactg ggaaatcagc gattgttttc tgacaattca
    33721 gttgtgaaat aaatcacatt aattaaaatg attctaaata agctgaagac gccgttaaat
    33781 caaaggttaa tttaattata atctacagaa aatataattg ttattaaagc gtttacaaaa
    33841 aacttttttg attccgttaa ggcaacttaa tattatggtt acctaatcac taatattgta
    33901 acctattttg gcatgagatc agggaatggc tgttatatta attggatatg tcttgtgcaa
    33961 atagtgcttg acggatttgt ggaattaggg taaaataatc tttgttgtgg cggtatagcc
    34021 aagtggtaag gcacggctct gcaaaagctt gatcgtcggt tcaaatccgt ctaccgcctt
    34081 ttatatacaa aacaagcctt gattaacttc gtgaaaacgt tgttaaatca aggtttttat
    34141 tttttgcgac aggataaaaa aagagaaaaa aagaaataaa gtcggtcaaa agtcggtcaa
    34201 atttcccgaa gatgtctttt atagcctgat tattaggtat gaaaaatact atggccaaaa
    34261 ttggtaaacg attgcaaatg aaggtcagag ttcttacccc cttaaacgat atgcgttaaa
    34321 agttagttga actgccgtgc acctaacgat agacacggtg atgtgagagc gagtagagtt
    34381 gaatctctac tcatttatct taccatagtc agctttataa agtaaccacc cattacaatg
    34441 caactatatt cttaatgttt ttaagcatgt tattgacaag tgttataaaa tgtgttactc
    34501 ttagtgagta aattagtttt tgagttagta tttgtgtttc aacatcttta tttctctcta
    34561 tttttacaaa tgatttttag aaaggaagtg gatgtatatg gcacaaggta cagtaaaatg
    34621 gtttaacgct gaaaaaggtt ttggttttat ttcaactgaa aacggtcaag atgtctttgc
    34681 acatttttca gcaatccaaa ctaatggttt taaaacgtta gaagaaggac aaaaagtggc
    34741 atttgacgtc gaagaaggtc aacgtggacc tcaagcagtc aatatcacta aattggccta
    34801 atctggttaa agtaactaag gagaagcaga tgttggaaac aacaactgct tttttgattt
    34861 ctaccagtta cctttaatga ttaagagttg cgtttaaggt cttgtatttg ttataataat
    34921 agtcagtttt agtcaaaatg tattgacgtg gtgctactaa gtttttagag tagcccgcaa
    34981 gcaaaggagt gacagcatgc caaccaaaaa tacttcagac agcattgaag agtatattaa
    35041 agaattatta gctaagtcag gaatagcaga aattaagcgg tccatgctag cagattcgtt
    35101 tcaagttgtc ccaagtcaga tcaactatgt cattaaaacc cgttttacgg agagtcgagg
    35161 ctatgaagta gagagtaaac gaggtggtgg aggctatatt cgtattgcca aggttcattt
    35221 ttcagacaaa caccatctga ttggcaattt aatggcaact attgaagact gtatcagtga
    35281 gcaagttttc acggactcga tacaattgct ttttgacgaa cacttattga cagagcgtga
    35341 gggaaatatc attttggcta tggcgtctga tgatgtttta ggaactgatg gttcaactat
    35401 tcgtgcacga atgctctatc gcttattgca acgaattgac agaaagggaa gcaattaatg
    35461 attatgtatt caacgaagat gcaagacatt tttagacagg cgcagttcca agctgctcgc
    35521 tttgatagcc attgcctgga aacttggcat gttttgttag ctatggtagc tgtagataat
    35581 tctttagcaa atatgatttt aagtgaatat gatgcccaag tcgccataga agaatatgaa
    35641 gctgcagcta ttttagccat gggcaaaacc cctaaggaac agttgtctcg tgtagacttc
    35701 agacctcaat ctaaaacctt gactaacttg ttagcttttg cgcaggctat tagccaaatc
    35761 actagggatc aagaagtcgg ctctgagcat gtcttatttg ctattttatt gaatccagat
    35821 atcatggcga gtcgtttgtt agaaatagca ggctatcaga taaaagataa cggcaatggg
    35881 cagccgcgat tagctgactt gcgaaaagca atagaacgtc atgcaggtta cagtaaggaa
    35941 atgattaagg ctattcacga actacgtaag cctaaaaaaa cgaaaacaca agggaccttt
    36001 tcagatatga tgaagccacc aagtacagct ggtgagttga gtgatttcac aagagatttg
    36061 actgaaatgg caagacaagg tttgttagaa tcggtgattg gacgtgacca agaagtatct
    36121 cgtatgattc aggtactaag tcgtaaaacg aaaaacaatc ctgtcttggt aggtgatgca
    36181 ggtgttggta aaactgcgct tgcttatggc cttgctcaac ggattgcaaa tggcgctatt
    36241 ccttatgaac ttaaggagat gcgtgtccta gaattagaca tgatgagtgt ggtagcagga
    36301 acccgttttc gtggggattt tgaagagcgc atgaatcaaa tcattgatga tattgaagct
    36361 gatggtcaga ttattctttt tgttgatgaa ctacatacta ttatgggatc tggcagtggt
    36421 attgacagta cacttgatgc ggctaacatt ttaaaaccag cattatcgcg cggcactctt
    36481 catatggttg gagcaacaac tcaagaagaa tatcaaaaac atattgaaaa agatgcagct
    36541 ctttcgcgtc gttttgctaa aatattaatt gaagaaccta atacagaaga tgcttatcag
    36601 attttgatgg gcctaaaatt atcttatgag acctaccata atgtctcgat atcaaatgag
    36661 gcagttaaaa cagctgtaaa aatggcacac cgttatttaa ccagtaaaaa tctccctgat
    36721 tcagctatcg atttattaga tgaagctagt gctgctgtgc aaaacatggt gaaaaaatca
    36781 gcacctgaga ctttaacacc aatagaccaa gctcttatca atggtgatat gaaaaaagta
    36841 tctcgcctct tagctaaaga agcaaaaggt cagatgagaa aaccaacacc agtcacagaa
    36901 gatgatattt tggcaacctt gagtaagtta tcgggaattc cacttgaaaa actgacgcaa
    36961 gctgatagca aaaaatacct caatttagaa aaagaactgc ataagcgtgt gattggtcag
    37021 gatgctgctg ttacggctat ttcaagagcc attcgtcgca atcagtcagg tattcgaaca
    37081 ggaaaacgtc ctattggatc atttatgttt cttggcccaa caggagtagg taagacagaa
    37141 ctagcaaagg cccttgcaga agttctcttt gatgatgaag cagcgcttat tcgttttgat
    37201 atgtctgagt acatggaaaa attcgcagcg tctaggctta atggagcacc tcctggttat
    37261 gtcggctatg atgaaggagg tgaactgaca cagaaagtta gaaataaacc ttattcagtc
    37321 ttgctttttg atgaagtgga aaaagcacat cctgatattt ttaacgttct ccttcaagta
    37381 ttagatgatg gtatattgac tgatagtcgt gggcgtaagg tcgatttttc aaatactatt
    37441 attatcatga ccagcaatct tggcgcaaca gccctgcgtg atgataaaac ggtcggtttt
    37501 ggggtcaaag gcattcacca agaccatcaa gctatggaga aacgtatctt agaagaatta
    37561 agaaaaactt accgcccaga atttatcaat cgtattgatg aaaaagtggt ctttcatagt
    37621 ctgacccaag ataacatgcg cgatgtggtt aaaatcatgg tacagcccct gattactaca
    37681 ttggcagaaa aaggtattac ccttaaaatt cagcctttgg ccttgaaaca tttgtccgag
    37741 gtcggctatg atgaacatat gggggcaaga ccattacgtc gaacgctgca aactgagata
    37801 gaagataagc tatcagagct tatcctttct cgagaattga caagtgggca tacgctaaaa
    37861 attggattat cacatggcaa attaacgttt cacatagctt aatttccata taaaaggtgg
    37921 atcatccttg atgtcaccaa aaaaagaggt tattcttaca aaaataactt cttttttctt
    37981 gactattttt gaccaagtga taaaatagaa tataaagtta gcactcgatg aacatgagtg
    38041 ctaactttac taaagattct tttattggag gaaaatttca tgttaaaacc attaggtgac
    38101 cgtgtggtcg taagatttga tgatgaaaaa gagcagacag tcggtggttt tgtccttgca
    38161 ggcactcata aagagtcaac acgaaaagcg acagtcctcg ctgtcagtga aacgggtgtt
    38221 cgcactatta caggcgatag cgtgctacct tcagtttcag tgggtcaaga ggttttagtt
    38281 gaaaatgggc atgatttaga agtaaccgta gatgatgaga aagtttctat catccgtgaa
    38341 tctgacatca ttgctattgt cacaaaataa aacgacaaat ctctaaatag aaagaaggat
    38401 tgaatatggc aaaagatatt aaattttcag cagatgcgcg tgctgccatg gtgcgcggag
    38461 ttgatatgtt agcagatacc gtcaaagtaa cgcttggtcc taaaggacgc aatgttgttc
    38521 ttgaaaaagc ttttggttct cccttaatta ctaatgacgg ggtaaccatt gctaaagaga
    38581 tcgaattaga agatcatttt gaaaacatgg gagcaaaatt ggtgtctgaa gtggcttcta
    38641 aaaccaatga tattgctggt gatgggacga ctactgcaac agttttgaca caagccattg
    38701 ttcatgaagg actaaaaaat gtgacagcag gtgctaatcc aattggtatc cgtcgaggca
    38761 ttgaaacagc aacagcaaca gctgttgaag ccttgaaagc cattgctcaa cctgtatctg
    38821 gcaaggaagc tattgctcag gtcgctgcag tatcatcacg ctctgaaaaa gttggagagt
    38881 atatctcaga agctatggag cgtgtgggca acgatggtgt gattaccatc gaagaatctc
    38941 gaggtatgga aacagaactt gaagtggttg aaggcatgca atttgaccgt ggttacctgt
    39001 ctcaatacat ggtcacagac aatgaaaaaa tggttgcaga ccttgaaaac ccatttatct
    39061 taatcacgga taaaaaagtg tcaaacatcc aagatatttt gccactactt gaggaagttc
    39121 ttaaaaccaa ccgtccatta ctcattattg cagatgatgt ggatggtgaa gcccttccaa
    39181 cccttgtctt gaacaagatt cgtggtactt tcaatgtggt tgctgtcaaa gcgccaggat
    39241 ttggtgatcg ccgtaaagct atgcttgaag acattgctat cttgacaggt ggtacagtga
    39301 ttacagagga tctaggactt gaattaaaag atgctacaat gacagccctt ggacaggctg
    39361 ctaagattac agttgataaa gatagcacag taattgttga aggttcagga agttcagaag
    39421 ctattgctaa ccgtattgca ctgattaaat cgcaattaga aacaacaact tctgactttg
    39481 accgtgaaaa actacaagaa cgtttggcga aattagctgg tggtgtagct gttatcaaag
    39541 taggagctcc aacagagaca gctttaaaag aaatgaaact tcgcattgag gacgctctaa
    39601 atgctacacg tgcagccgtt gaagaaggta tcgttgctgg tggtggaaca gcacttatta
    39661 cggttattga aaaagtagca gctcttgaac ttgagggcga tgatgctact ggacgtaaca
    39721 ttgtgcttcg tgctctagaa gagcctgtac gtcaaattgc tttaaatgct gggtacgaag
    39781 gctccgtagt tattgacaag ttgaaaaaca gccctgcagg aacaggattt aatgctgcaa
    39841 caggtgagtg ggttgatatg attaaaacag gaatcattga ccctgtcaaa gtaacacgat
    39901 cagcgcttca aaatgcagct tctgtagcta gtcttatttt gacaacagaa gcagttgtcg
    39961 ctaataaacc tgaaccagct gcgccagcgc cagcaatgcc agcaggtatg gatccaggaa
    40021 tgatgggcgg cttctaaggt ctctatagca ttaaggatta tgaaaaagaa gttgagacta
    40081 aaggtctgct tcttactatg aaaaaagaac aaagattgga tttcgactca tgatatccca
    40141 tctttgtttt tttagttgtg atataaaatg ctaatctttg tggttacaga cttttaatgt
    40201 attggaaaat acattgtttt tctttgtcat gtgctatcat ggagtcaatg aaaagttatt
    40261 cccatatatg ggtgttggag gtctgtgatg aatcattttg gagagatttt aaaaaccttt
    40321 agagaatcaa agggattacg attaaaagat gtcgcaaagg ctggtatatc aacctctcag
    40381 ctgtcgcgtt tcgaaaaagg ggagacggac ttaaccatat cgacatttat gctgattttg
    40441 gatgaaagta acatgcccat tgatgagttt atgtatgctg tccatgattt tcatcgtgac
    40501 gatttaaatg aactcttatc aaaaagtgag gcatttcgta acaactcaag atagtgatgg
    40561 cttgaagcag ttacttcatg ctcaactagc ataaactgat aagaaggaga tgttcacgga
    40621 tatcttttgg catatccagc atgtctaagt ctgctatggc atgctatttt gggagtccct
    40681 cacgcgactc tgtcagtagc tctccttcaa aggattcaca tagaaagtcg taatagacat
    40741 agcagtcagg cttgataaag ctagaaatac tctttaattg aaggtttaaa gctgtcagac
    40801 ctatctcttc ttttagttct cataaagccg cttcaaagaa agattcacag ggctcgactt
    40861 taccttctgg ctggacccat cctgggaagt tatcgtgttg tctatggagt cataaaatca
    40921 tatcgttatg tttgacacac atattgcccc agtctctaac cgttgttatc accagattca
    40981 ccacctttta gtatagtata agaaaaaagg ggtaaaagag gtttcttgtt gcttttttgg
    41041 cttaaggttt ctttaagtct tatctagtat actaatgtca ttccttaata ggataagtat
    41101 ttggttgtag aagtatcgtc ttaaactaac gctatctcaa cccgattccc atcttattca
    41161 cccctcctat accgataagg tctcacaaag tgtgagacct tattttttga cttcagctct
    41221 agttatggag aaacttgttg atacaagctt ttttgggtta tggtattatg atctattcaa
    41281 gcctttcttg tttttgggtt tttctttaac caacttggct tcaatagctt ttaagcgttt
    41341 gaaggttttt tcagcgcgat ctagtgaaat cttatcagct ttttcttgag cagctttggg
    41401 gtcactgacg actaagtcac tgatttcttt ggtgcttttg tcttgttcgg ctatccaggt
    41461 tttttccaag cctttcatct catcaatcac tttagttcca aatggttttg gatgagcagc
    41521 cacgagatca ttaatgtgtg acaccgtcca ataccatgac ttatcgttat attgggtgct
    41581 tttttcttga taggcttcat aggttctact gatattgcca aggtatggca agtaaggggc
    41641 gttacgagga ctgccaatag atagccacat gacaccacca cccaattcag cagggatgtc
    41701 ttttttcagt tggaaaatat gagcttccat gacattagga tttgagatgg gataagcata
    41761 acctttaaca gcttttttgg attttggttt acccttaccg tctaatgcca tctgatcaag
    41821 tggtttaaga tccagcccct caaaacgatt acgttgcagt ttcatcgcat cttctagact
    41881 gaaggtctta tcagtgcttt ggagcaactc ataattgctg tctttataag ttacttttga
    41941 atcagggtca agtgatttaa tccctgagaa agagcgagag cggttggcat cgtttagtgg
    42001 cggattgtaa gatttggcaa tatgaaattt accatcaact tcgatataag atttggcttt
    42061 tttagcgact ttttccacat cttctgaggc aatcgtattt tccttatcgt tgaaatcgac
    42121 atgtccgaga tagaaggtat ttggaaaaac agcgtattta tcatctggga atttgatggc
    42181 aacgtattgg tgaccagaga gaatttccat gtaccagatg ccgtctttgt cagccaaggt
    42241 aacaatattt ccttcagcag ctcctttttc agtgactatt ttagcaatca atgcgacacc
    42301 ttcacgggct gttttgacgc ttggtaaaat gacactggcc atagatgatt ccgctaagcc
    42361 atttttgacg taaggatcaa ttttttggat ggcatcatta gctgaagctg atactgttgc
    42421 agacatagag acgccaaact cattaaaacc agcttcgtca taaacgcctt tgttaggtgt
    42481 tacatcagga atcgcactat agcgataaga atgctcaggc aacgggtact caaaaccatt
    42541 agagaggtct ttccattttt cgccagcagg attgtccttt gctagacgta caatgaaatt
    42601 tttattatga tgtggctcaa gatcttctgt tcgaccataa agaagagaac cgtctttggt
    42661 taaatctttg ccaataataa aaccagtaca agcataacta acactttgaa gcgaaaaggc
    42721 tgtcagaata cttaaaactc caagtgatat ttttttgttt atcatgcgaa tcctcctagt
    42781 aaacgataac gctttcacag acattataaa atgctctttt taaaaattca agtcttttat
    42841 gaagtgtttt gaaattgtta gctatctaaa tattatgaga attctctctt gaattttggc
    42901 ttaacggccc ctaaaaacgt ataggcagtg aactatctag gtttcttcga aaatccatta
    42961 gccatttatg atataatagt aaagaaaaac atagaaagtt ggggtctgtt gatgaccaaa
    43021 ccatttcatc ataagaaact aaaacaaata actataatag ctgcaactag ccttttttta
    43081 ttcctgatcg gtggtgcctt ttactactct aaaaatcatt gtattaatgc ctatcttaaa
    43141 gctcgatcag cccaatcagg accagttttt gagaatatca aagcatatct agtctgggat
    43201 gatactaatg agcagatcac aaatgacgag gcgatgtata ctaagtttag aaggtatagt
    43261 caaaaagaat tgaggcaaaa aaagcaggat ttaaaagctg ctagtcaaga tagtgccgtt
    43321 caagtaaagt ctgttggtcg tcgtttttgg atttttcctg attatcggat tgccataaaa
    43381 cccatggatt taacgataaa aacgaatgtg cctcaagcag acgttctttt aaatcaaaaa
    43441 aaagttgctg tttctgattc agaacagttc tcagtcaagc ttgatcggct accaacggca
    43501 gaatataccg caagtatcag aggcaaacac aacgggcgaa acattaaagt caataaatca
    43561 tatgatggtg ataatcccgt gctagatttg agtgtgtctt ttagaacttt tttagtaaca
    43621 agcaatgcta agcaaggaga tctttacttc gatgataacc atattggcac attaaaagat
    43681 ggtcaattac aagtagaaga ttaccctgtt acagaaaacg cacaagctta tatgaaaaca
    43741 acattcccag atggtgagtt aagatcacaa aaatatgctc tagctgatgt tgaagaagga
    43801 gcaaccctgg agattttagt tacagatctt ttagaagagg acaaagcagg ggagctatta
    43861 gtatcagctt ttgatcagct gatgcactac ctcagtacag gtcaagactc atctaactta
    43921 cgtagcgtct ttgaggcagg gtctagcaac gcattttata ggggattgaa agagtccata
    43981 aaagcgaaat ttcagacaga tacaagaaaa gccagccgtc tcaatattcc atctatcctt
    44041 ttgacaacaa tgactcaagt gggcaaaaca atttacgtgc ttgatttcac agctacctac
    44101 gaatttttgt atgacaactc aacagatcct gagcagcata cctctggaca tattaatcaa
    44161 gacttgactg gaaaagtgac tgtaaaaaaa gttggacagc attaccttat cagccagtcc
    44221 ggctccaaaa atattactgt tgttaaagag gacaatcaac tcaaagcgcc atctgtcttt
    44281 cctgagtcta ttttgggaac gtggacaggc caagccaatg gtttgagcat ccatatgtct
    44341 ctagcatcag atggaacaat tacgactaaa gttgaagatc aaaaaggcaa ccgttctaaa
    44401 gaaactcgga cagctaaaat tagtaaagtt gaagacaaag gcaatggttt ttatctttat
    44461 acgccagatc ctggaagtga cataagcgcc ttagctccag aaggaggatt ggggggtgca
    44521 aatgtcaaat atgcttatgg tttcaaaata tctggtaaaa cagcctctcc agtggtgtgg
    44581 caggcagcat taacacatga atttgattat accaaaccac tttcgggagt aactttgcaa
    44641 aagcaaccat aaaggatgca aagccacaaa gaacagtaga aacaatgtta ttactcaaat
    44701 acagtgctat gaaaacagat aaactcaaaa ggctaggaga ttatttccta gccttttgag
    44761 cgtttaagac tgcgtcaaat gtagctgatt tagcttgcac gcaaatgtct tctcgggtta
    44821 gagggtgttt caaacgtaat tgataagcat ggagcatcag tcgagcacaa tctttttttc
    44881 cattagaata caaaggatca ccaaataaaa catgaccttg atgggctaaa tggactcgaa
    44941 tttgatgagt ccgtccagtt tgtaattgac aattgagtaa gcttgccgtt ttgtggaagt
    45001 ttttgactag agttacctca gtaatagctt tcttgccatt tatcggatcg acaacacgtt
    45061 ttctgcggtc atgtcgatga cgaccaattg gatgatggta agttacccta ggactgtcta
    45121 aggatccgtg aactagtgcc aaatattctc gatggatgtc tcttttttct aaaagacgat
    45181 taaggattgg taagataaaa ggtgttttag caaataaaat ggccccactt gtttccttat
    45241 ccagacgatg aaccacatag caggtctgtc ccgtgtaagc agacacgtgg ttgagcagcg
    45301 ccaactctgt tggatcattg ccgtgtgttt tcatcccttc aggtttgtta acaataatga
    45361 tgtgctcatc ttcataaagg caggttactt tttcggcctg ccccatcacg ataatctttt
    45421 caggataatc ttcgtgatcg aaaaaaagtt tgacctgatc accgtattta acacaacttt
    45481 gccagttaac aggatgacca ttaataagaa catgtttttt agttctcaga aaatgcctaa
    45541 ttttacgggg aattaacaat tgttcctcta ataatgcttt gaccgtcaat tcttcaaagg
    45601 gatttttcag tgtgacagta aacccctttg atggtttatt tgttgtcttc attgagccag
    45661 ttatggtatt tttcaacaag gttgatagcc atttgggtgg caagagcagc agagaaagct
    45721 tcagtacctt cacgctcgtc attagctacc tccaagcgag tctcatcgta aatggctttt
    45781 agactttctg cggataaggt ttctttaaaa gcttggaatt tattcattgg ttaaacccgt
    45841 ccttctatgt ttaatgtgag ctcctgatta atgcaaggaa ttcaatgcta ttatagcatg
    45901 tttctaatca aaacgtgcca ctcaaaaagg taaaaacgtt attttgctaa tccatctaat
    45961 aagaaagtgt cttaaataag acctcttgat agagtttgta acaaaaatga tatgaaacta
    46021 ggtgctaacg cagaaataga aaccaactaa cgtgttgcga agttggaaca gtcataaaaa
    46081 atagcaagat aaaacttatc aacacacagt tacctaagac gatgagtcaa acaggtatgt
    46141 tctttcaaaa caaccccatg aggttgaacg acgtatcgga aaaatacgga ttagtttggc
    46201 cttatgatag gtatttctct atcgtaaaag aagtcaacca aaggttttta atataaaata
    46261 ttaagaaaaa ttgttataat tatgataaaa acataatcgt aaaatagagg aaaaacaatg
    46321 aaaacaatta gacgttatga tgttaacgaa gatagagggc atacaggcct tgtagaagca
    46381 ggagacttct attatttaaa ctattgtgtc ggcaatgtcg gacaagacat tgaaagtcag
    46441 attaatggag cctttgacga gatggagcgc cgattagcat tggtggggct cacattagat
    46501 gcagttgttc aaatggattg tctatttcga gacgtttgga acatacctgt gatggaaaaa
    46561 atgattaaag agcgctttaa tggcagatat cctgctcgaa aatcgattca aacggaattt
    46621 gcacatcacg gtggaccaca aggactactc tttcaagtgg atggtgtggc ttattcaaaa
    46681 catatttcga tgacctaatc aaggttactt taagatcata gtggtataat aacgttatga
    46741 gatttctaga acttttacaa aagaaatttt ttcctaaagc atatcaggaa aaacaattct
    46801 taatgcatca aaaaacgcgt ttaacgccac aacacaatca aaagcagtat tcgccaaatg
    46861 ccaatcattt ggactcatca gctaccaaaa actcagaaca agaccctgca atagctctgc
    46921 aacgcagtag agcctatgaa ggaagcccta aaagtcggcc cgcttggttg caaaagctgg
    46981 aagctgtttt gccgtctcct caacatccaa ttcggcgttt ttggcgccgc tatcacatcg
    47041 gaaaactgct aatgattctg attggaactc ttgtcttact cttaggatca tacttgtttt
    47101 acttatcaaa aacagctaaa gtatctgatt tacaagatgc cttgaaggct acaactgtta
    47161 tttatgatca caaaggagag tatgcaggca gtttatctgg tcaaaaaggg agttatgttg
    47221 agctcaacgc tatttcagat gatcttgaga atgctgttat tgccactgag gataggactt
    47281 tttacagtaa tagcggtatt aatcttaaac gcttcttatt ggcggtagtt acggcgggcc
    47341 gctttggagg tggctcaacg attacacagc aactggctaa aaatgcttat ctctcacaag
    47401 atcagacaat taaacgaaag gccagagagt tttttttggc gttagagttg accaaaaaat
    47461 acagtaaaaa agatattctt actatgtacc ttaacaactc ctattttgga aatggagttt
    47521 ggggagttga agatgccagt caaaaatatt ttggaaccac agctgctaac ttaacattgg
    47581 atgaagctgc cacattagca ggtatgctca aaggacctga aatatataac ccttaccatt
    47641 ctctaaaaaa tgctactcac cgtagagata ctgttttagg agcgatggtt gatgccaaaa
    47701 agattaccca aacaaaagct cagcaagcta gagcagtagg gctaaaaaat cgcttagctg
    47761 atacttatgt tggtaagaca gatgactaca aatacccatc ctactttgat gctgttatta
    47821 gtgaagcaat agcaacttat ggtctttcag aaaaagacat tgttaataat ggatacaaag
    47881 tttacaccga gctagatcaa aattaccaaa ctggcatgca gacgactttt aacaacgatg
    47941 aactatttcc tgtttcagct tatgacggta gctctgctca agcagctagt gttgctttag
    48001 atcctaaaac aggaggtgtt agaggtctga ttggtcgtgt gaatagtagt gaaaatccga
    48061 ctttcagaag ttttaactat gcgactcaag caaaacgtag tcccgcatca acaatcaaac
    48121 cactcgtggt ttacgcgcca gccgttgctt caggatggtc aattgaaaaa gaactaccaa
    48181 ataccgttca agatttcgat ggctatcagc cacataatta tggaaattat gaatcagaag
    48241 atgttcctat gtatcaagca ttagcaaact cttataatat tccagcagtt tctacattga
    48301 acgatatcgg aatcgataaa gcctttacct atggtaaaac atttgggtta gatatgagct
    48361 ctgccaaaaa agagttgggg gtagctttag gtggcagcgt gacaactaat ccattggaga
    48421 tggctcaggc atatgctgcc tttgccaata atggagtaat ccatcctgcg cacttgatta
    48481 accggattga aaatgccagg ggtgaagtgc ttaaaacctt tactgataag gctaaacgtg
    48541 ttgtcagcca gtctgttgca gataagatga cagccatgat gctaggtacc ttttcaaatg
    48601 gaacagcagt caatgctaac gtatatggct atacactagc tggtaaaaca gggacgacag
    48661 aaaccaactt caatcccgac ttagcaggcg atcagtgggt tattggttat acgccagatg
    48721 ttgttattag tcaatgggta ggatttaatc agaccgatga aaatcattat ctaacggatt
    48781 caagtgcagg cacggcttca gctattttta gcactcaggc atcttacatt ttgccttata
    48841 ccaagggcag ccaatttcat gtagataatg cttacgctca aaatggtatt tcagctgttt
    48901 atggagtcaa tgaaacaggt aatcaatcag gagttgacac tcaatctatt attgatggtt
    48961 taagaaaatc agcacaagaa gcttcgcaat cactatcaaa agcagtcgat cagtcagggt
    49021 tacgtgataa ggcccaatct atttggaaag agattgttga ctattttaga tagcttgcag
    49081 tattttagag atcgtgttaa aataatagtt acggaggcgt tatggcacag aaaaaagcga
    49141 gtctagcgtg tgtcgaatgt ggcagtcgta actactctat cggagtgagt agcacgccaa
    49201 aaccaacacg tctagaagta aataaatttt gcaaatactg caaaacatat accttacaca
    49261 aagaaacacg ttaaaaagga gagcctgatg ggattcatta gcgggacttt taaagtctta
    49321 aaagacacaa catggccaaa tcgtaaacaa cgttggaaag attttatctc agttcttgag
    49381 tacacagctt tctttacggt gattatctac atctttgacc agctcttagc aaagagtgta
    49441 ttagcactga ttaatttatt ctaggtcaag attggtagaa atgataagct tgcttggaaa
    49501 agcctaggct gggagtattc ccagcctttt ttgtagtatc aataatctga ttagtaagct
    49561 tttttaaagc ccatactggt ttgagcttta aaaaagcata aaggtaaagg caatgtagca
    49621 acgatctcca aaccaagtgc attaaattag cttgtaacag agtcaacgca taaacagcct
    49681 ggcctcactt gcttagcaca ttaaaaatag caatgaatat tatggttgag gaaaacagcc
    49741 tgatagtctg ctaaatcttc gggatgataa gccttgacct cagccatctc atactcccta
    49801 cctagaagtt tgtacttgtt ttctccaaat tgatggaaag gtaacagttg cacttggtca
    49861 atctcaagct gattaaagag ctctgagaag gctttagcat cgtctaggga atcattaaat
    49921 tggggaataa cagggatgcg caagacgatt tcttttccag cttgaaaggc ataatgaata
    49981 tttttgataa tcaagtcatt acgaacccca gtcacttttt ggtgtctgag ctgattataa
    50041 tgtttcaaat cggtatagat aaagtccacg tagtcaataa gggtgacaaa ttgctcgtgt
    50101 ttggcaaagg cggtggtttc aattgcggtg tgaagacctg ctgctttggc tgcttttaac
    50161 agggctaagg caaagtcaaa ctgagcaaag atttcccccc ctgacagggt catgccccca
    50221 cctgactctt cgtagaaatc aaggtcttta aggacttctt cgatcacctc gtccacggtt
    50281 ttttcctctc caactatttt agtattaagc ccatcacttg ttaacatctg ctcaggcact
    50341 ttttgttggg attcgggatt ggcacaccaa ggacatctca aggggcaacc ttttaaaaaa
    50401 acggttgtcc gaataccagg gccgtcatga atactaaaat gttggatgtt gaaaacaata
    50461 ccgcgatcag tcataagtgt gaattccttt cgttgtaaaa ccatcatacc agataaacgt
    50521 aaataaatca attacgaatg aaagtaaata tcccttttct tttaagaaaa taactggtac
    50581 aatgaaaggg aggtgaatga tgaatcgatt agaacgtatt attcaactgg tttcccagaa
    50641 gaaaaaaata gatgttaaca gtttatcaga gcaattagac gtttcgaaag taaccattcg
    50701 aaaagacctt gataagcttg aaagtaaggg cttgttgcga cgggaacatg gctatgcggt
    50761 gctaaacagt ggcgatgacc tcaatgtacg cttgtcctac aattacaaca taaagcgacg
    50821 gattgcagaa aaagcagctg aattggtaca agacaacgat accattatga ttgaatctgg
    50881 ctcaacctgt gcccttttgg cagaagtgct ttgccagacc aaacgaaata ttaaagtcat
    50941 taccaattcg tgcttcattg ccaactacat tcgtcaatat agtagctgtc aaatcatttt
    51001 actgggcggt tattaccagc ccaattcaga ggtgactgtt ggtcctttat tgaaagaaat
    51061 gatatccctt tttcatgtca atcgtgtctt tgttggaaca gacggtttca acaaagatct
    51121 tggctttatg ggcaaggaca tgatgcgctc agaaggggtg cgttacatgg cagatgctgc
    51181 tgaggaagtg gtgattctga ccgattccag caagttttca aaaaccagtc tggtacacca
    51241 gttgtcatta gctgatgtca atcgcgtcat tacagaccaa gcactagaca agcaaacaca
    51301 agagttatta agtgctagtg gtcttgttct tgattttgtt tcttagaaaa taggtggcta
    51361 gatgaaagaa gaacgcagac ggctccttgc caaggtggct tacttgcatt atgttcaagg
    51421 caagagccaa accttgattt caaaggaaat gaatatctac cgaacaacgg tttgtcggat
    51481 gttagcaaaa gccaaggaag aaggcattgt tcggattgaa attgccgact atgatgctga
    51541 tttatttgct ttagaagaat acgtgcgaca gcagtatggc ttggaaaaac tagaccttgt
    51601 gcccaaccag gttgaagata ccccaatgga taccttgaca aatgttgcta aaacagcagc
    51661 tgaggttttt agacatgttg ttaaagatgg cgataagatt ggtctgtcct ggggagcgac
    51721 tctttcttgc ttgatggatg agttaaatcc aaaagcgatg aaagatgtgt ttatttatcc
    51781 tttggcagga ggacctagcc atattaatgc caaataccat gtcaataccc tggtttaccg
    51841 cttggctcgc atctttcatg gtaatagcgc ttttatgaac gctatggtca ttcaagaaga
    51901 caaacacttg gctaagggaa tcttacaatc taaatacttt aacgacatct taacaagctg
    51961 ggaccagcta gatcttgcct tagtaggaat tggtggggag cctaatagcc ttgagcagag
    52021 tcaatggcgt gatttattaa ccagctcaga tcatgaccaa ctcaaatatg aaaaagccgt
    52081 tggtgaagtt tgttgccgtt tctttgatca ggcaggtcag ccagtttaca ctggcctaca
    52141 ggatcgaact attggtattt cgctagaaca gttgaggcgt gtccccaaaa caatggctgt
    52201 tgcaacaggt aaacacaagg ctaaggcaat attggcagcc ttaaaagcag gttttatcaa
    52261 ttatctagtg acggataaag agaccatgct agctgtttta gcgttagatg aagatattga
    52321 tcttaataac gttcttcttt aatagaaatt caaagatact atgatatgta tagaggccca
    52381 agaccaaacg tcagggcttt ttttgtttga tgtgttgatg aaacagagat tgctcaaatg
    52441 tgcagttaat gtattggcac aaaagtgcat taaccaaaat atagcacaaa atatattgac
    52501 cctaaaaaca aaaatgatac aataaactta ccaacgaaat gtaaacgatt acaaacacaa
    52561 taacatcacc ttcgaaaaaa aggctcattg ccgttacatc acataaaaaa gaaaaaaagg
    52621 agacaccaat gcaagttatt gtaccagacc aaatcattat gggcttaatt ttaaatgcag
    52681 gcgatgccaa acaacatatc taccaagctc tgaaatgtgc taaagaggac gattatgcca
    52741 ctagtgaaaa agagatggcc ttagcagatg atgccttatt agaagcccac aatttacaga
    52801 cccagtttct tgcccaagaa gctagtggta ataagtcaga gattacagct ctttttgttc
    52861 actcacagga tcacttgatg acgaccatta cagaaattaa tctcgtcaag gagattattg
    52921 accttcgtaa agaattggca accaaataat atttcattca taaaaaggag attgacatga
    52981 ttaaaattgg attgttttgt gcagcaggat tttcaaccgg tatgttggtg aacaacatga
    53041 aagtagctgc tgaaaaaaaa ggcattgatt gtcagattga agcctatgct caagggaaat
    53101 tagcggacta tgcaccatta cttgatgtgg cacttttagg cccacaggtt gcctatactc
    53161 tggatcaatc agaagctatt tgtaaagaca atgatatccc cattgcagtt atcccaatgg
    53221 ctgattatgg aatgttagac ggcaacaagg tgcttgattt agcccttagt cttgttaaag
    53281 aataggagtc aatcatggca aaaatgaata tgcaaaacat catcatgcca atcatgaaat
    53341 ttgtgaatat gcgcggtatc atcgccttaa aagacgggat gttagctatt ttacctttga
    53401 ccgttgtggg aagtcttttc ctgattgctg gtcagattcc ttttcaaggg attaatgatg
    53461 ccattgccgg tgtgtttggt gccgactgga cagaaccctt tatgcaggtt taccatggaa
    53521 cgtttgctat tatgggcttg atttcctgct ttgcgattgg ttattcttat gctaaaaatt
    53581 caggtgttga acctctccct tcaggggttc tatccttatc agctttcttt attctattga
    53641 gatcatctta tgttccagca gaaggcgaac ctgtcggtga tgctattagc aaggcttggt
    53701 ttggtgggca agggattatt ggtgctattg tgattggttt aacggtaggt gctatttata
    53761 cagcatttat ccgtcgccac attgtcatca aaatgccaga gcaagtgcca caagccattg
    53821 ccaaacagtt tgaagctatg attccagcct ttgtgatttt taccttgtca atgcttgtgt
    53881 acattattgc caagtcagtg acaggtggtg gcacctttat tgaaatgatt tatgatgtca
    53941 ttcaggtacc gctgcaaggg ttaacgggtt ctctttatgg cgcactaggt attgccttct
    54001 ttatttcctt tctttggtgg tttggcgtgc atgggcaatc tgtggtcaat ggaattgtca
    54061 ctgctcttct cttatcaaat ctagatgcca ataaggcctt gatggcagca ggtgagttat
    54121 ccctagacaa gggtgcccat attgtaaccc aacaattttt agactctttc ttgattctat
    54181 caggttctgg cattaccttt ggtttagtgg tagctatgat ctttgcggct aaatccaaac
    54241 aatacaaggc tttaggtaag gttgcagcct tcccagccct ctttaatgtt aatgaaccag
    54301 ttgtctttgg ttttccaatt gtgatgaatc cagtcatgtt cttgccattt atcttggttc
    54361 ctgtcttggc agctctcaca gtttatggcg ccattgctat tggtttcatg cagccctttg
    54421 caggagtgac ccttccgtgg tcaacaccag ccattatctc agggttcatg gttggtggct
    54481 ggcaaggagc tattgtgcaa attcttatac tcatcatgtc aacgttggtg tacttcccat
    54541 tctttaaaat ccaagataat atggcttatc aaaatgaaca agctagtgaa gagtcatgat
    54601 ttagcgtcca cacaaattct tgagaccatc tccagttaga ggtggttttt tagaaaaaga
    54661 agagcgactt atcaggccta tattgcacaa tagtgcaaaa taaagtgact atctcttctt
    54721 atggttaagg atacgcaaaa gtcgcaatat atgataaaat agttacgaaa gaaacattta
    54781 taatttcgta agaaagaagg agaccccgca tgactgaaac aaaaagccct tattttggac
    54841 atttaacaga cagaatgact cactatcgtg aagctgtgtt agacaagaaa ccttatattg
    54901 atgctgagcg tgctatttta gccactgaag cctatcaaaa acaccaaaat aagccagcaa
    54961 acctcaaacg cgcttacatg cttcaaacta ttttagaaaa catgaccatc tatattgagg
    55021 atgaaagcct cattgctggt aaccaagcct cttcgaacaa ggatgcgccg attttcccag
    55081 aatacactct ggaatttgtc ctcaacgaac ttgatctttt tgaaaaacga gatggggatg
    55141 tcttctacat taccgaagaa accaagcaac agctccgaga cattgcccca ttctgggaaa
    55201 acaataacct gcgtgctcgc tgcggtgtct tgctaccaga agaagtgcaa gtgtacatgg
    55261 aaacaggttt ctttggcatg gaaggcaaga tgaactctgg ggatgcccat ttagcggtta
    55321 attaccaaaa actcttggaa cacggcttaa agggatttga agaacgggca cgagctgcca
    55381 aggctgcgct tgatctgacc attcctgaaa acattgacaa ataccatttt tacgactctg
    55441 tttttattgt cattgatgca gtcaaaactt atgctaaacg ctatgccaag ttggctagag
    55501 aactagcaaa aacggctaaa ccagaacgtc aagcagaatt gttagacatc gcacgcattt
    55561 gtgacaaagt gccttacgaa ccagcgaaaa cctttgcaga ggctgtacaa tccgtctggt
    55621 tcattcagtg tatcttgcaa attgaatcaa acgggcattc cctatcttat ggccgctttg
    55681 accagtacat gtatccttat gtcaaagctg atttggaggc tggccgtgaa acagaagcct
    55741 caatcgttga acgtttgacc aacctctgga ttaagacctt gaccattaat aaagtacgga
    55801 gccaagccca caccttctca tcagcaggta gtccacttta ccaaaacgtg acgatcggcg
    55861 gtcaaacacg cgataaaaaa gacgcggtca acccactgtc ttaccttgtc ctacggagtg
    55921 tggctcaaac caaattgcca caacctaact tgactgttcg ttaccataaa ggcctagaca
    55981 atacctttat gaacgaatgt attgaggtca tgaaacttgg ttttggcatg ccagccatga
    56041 acaacgatga aatcatcatt ccatccttta tcaaaaaagg tgtctcagaa gaagacgctt
    56101 atgattattc agccattggt tgtgtggaaa cagcagttcc tgggaaatgg ggctaccgtt
    56161 gcacggggat gagttacatc aacttcccta aaatcttgct gattaccatg aatgacggga
    56221 ttgacccagc atcaggcaag cgctttgcaa aaggacacgg tcatttcaaa gacatgacct
    56281 cttatgaaga attaaaagca gcatgggatg ccaccctgcg cgaaattacc cgcatgagcg
    56341 tcattgttga aaatgccatt gacctaggtc ttgaacgtga agtaccagat attctttgct
    56401 cagccttgac agatgattgt atcggtcgtg gcaagacctt aaaagaaggc ggagctgttt
    56461 acgactatat ctcaggcctt caagttggta ttgccaacct atcagactcc ctagcagcgc
    56521 tgaaaaaatt agtgtttgaa gaaggtcaat taactccaga agaactctgg caggcccttg
    56581 aaagtgactt tgctggagag cgcggagaag agatccgaca aatgctcatc aatgacgcac
    56641 caaaatatgg taatgatgat gactacgcag atagtttagt tgtcgaagct tacgacacct
    56701 acattgatga aattgccaaa tacccaaata cccggtatgg ccgtggccca atcggaggta
    56761 tccgctattc tgggacatca tcaatctcag ccaatgtcgg acaaggaaaa gggaccttgg
    56821 caacaccaga cggtcgccat gcagggacac cactagcaga aggctgttca ccagaacaca
    56881 gcatggacaa aaaaggcccg acttcagtat tgaaatctgt tgctaaatta ccaacagatg
    56941 agattgtcgg aggagtgcta ctcaaccaaa aagttaaccc acaaaccctg gccaaagaag
    57001 aagacaaact gaaattaatg gccttacttc gtactttctt taatcgccta cacggttatc
    57061 atatccagta caatgtcgtg tcacgtgaaa ccttgattga tgcccaaaaa catcctgaaa
    57121 agcaccgtga cctcattgtc cgtgttgccg gctactcagc tttcttcaat gtgctctcaa
    57181 aagcaaccca agatgacatt attgaacgta cagaacacac actttaggag aaaataagta
    57241 tggaatacat gttagacact ttagatttag aagcgattaa aaaatggcat cacattttgc
    57301 ctctcgcagg tgtgacctca aacccttcta ttgccaaaaa agaaggtgac attgatttct
    57361 ttgaacggat tcgagaagtc cgtgctatta tcggtgacaa ggcttctatt catgttcaag
    57421 tgatcgccca agattacaaa ggcatcttaa aagatgctgc tgaaatccgc aggcaatgtg
    57481 gagatagtgt gtatgtcaaa gtacctgtaa ccacagaggg ccttgcagcc attaaaacct
    57541 tgaaagctga aggctatcat attaccgcga cagctattta cagcactttc caagggttat
    57601 tagccattga agctggcgct gattatttgg ctccttatta taaccgtatg gaaaatctta
    57661 atattgatcc agaggccgtg attgggcaat tggcagaagc tattgaccgt gagtgttctg
    57721 acagtaaact cttagcagcg agctttaaaa atgtggctca ggtcaataaa tcctttgctc
    57781 taggagcaca agccatcact gctggcccag atgtgtttga agcaggattt gccatgccat
    57841 ctattcaaaa agcggttgac gattttggca aggattggga agccattcat caccgcaaga
    57901 gcatttaaga aatagcatca gtagtaatca catcattagg aatcacagat aaaggagttc
    57961 aacgatgaaa gtatttgcaa gtccatctcg ttacattcaa ggtaaaaatg ccttgtttac
    58021 caatgctaaa accctaaaac aactaggaaa tagccccatt ttactgtgtg atgacgtggt
    58081 gtatggcatc gtcggagaaa gatttgaaag ctatttgata gataatggca tgactcctgt
    58141 tcacgtagcc tttaatggcg aagcctcaga taatgaaatc agccgcgtgg ttgccattgc
    58201 caaggaaaat ggcaatgatg ttattattgg acttggtggt ggaaaaacca ttgacagtgc
    58261 taaggctatc gctgacttac ttgctgttcc ggtgattatt gccccaacca ttgcttcaac
    58321 agatgcccca acctcagcct tatcagttat ttacaccgat gaaggagcct ttgaaaaata
    58381 cattttctat tcaaaaaatc cagatcttgt tttggttgac acacaagtga tctgtcaggc
    58441 accaaaacgc ttattggcgt ctgggattgc agatgggtta gcaacatggg tagaggcgcg
    58501 tgctgttatg caaaaaaatg gagacaccat ggcaggtggc aatcaaacct tggcaggagt
    58561 tgccattgcc aaagcctgtg agcagacctt gtttgcagat ggcctaaaag cgatggctag
    58621 ctgtgacaga caagtcgtga ccccggcctt ggaaaatgtc attgaagcca atacacttct
    58681 tagtgggctt ggttttgaaa gtgcgggtct ggctgctgca catgccattc acaatggctt
    58741 tacagcgctg acaggtgcta ttcaccacct tacccatggt gaaaaagtcg cctatggtac
    58801 gttgacccaa ctcttcttgg aaaatcgttc gcgtgaagaa attgaccgtt acatcgactt
    58861 ttaccaagcc attggcatgc caacaaccct caaagaaatg catttagaca cggctactca
    58921 agaggatttc ttaaaaattg gccgtcaagc aaccatggca ggcgaaacca tccatcaaat
    58981 gccgtttgtt atcagtccag aagatgtagc agcggctttg gttgctgttg atgcctatgt
    59041 tacgagtcga taggctaacc aaaaagagat ttcttatttg ccagataacc tcaaaaaaac
    59101 aagtctaggg agtcacttcc tagacttgtt ttgcttattg ttggttggta atagcacttt
    59161 tagcggggtc attgtgggca atacgactgg cagctgcagc agcaatggcg ctaacaatat
    59221 catctaaaaa ggtatggcag gagttgccat ctttatggtt gagtttgtca acaattcctg
    59281 gttttgtctt gtccagatac ccataattgg taaaaccgat agacccatag aggttaacaa
    59341 tggataaggc caggatttca tcaatcccat acagcccttg gtcggttttc aagatactaa
    59401 ggagtggctc agacagctgg ttggcttcag ccaatttatc taattctacc ccagtgataa
    59461 tagcgttttg cacttctcgt tttgcaagca ccgcctcaac gctctctaaa cattctgcca
    59521 tggtcaaatt gggaatataa tcattctgca aaaaaagcac cagctctgca atagcttcta
    59581 aagaaccccc tcgctcagcc agtaattgat aagacacttc tcgtaggtga tggtcagttg
    59641 acatgtgaga cctccttttt ttctttattg taacataaaa gatttcgaga aacctctaca
    59701 acagctaaag aggggatagt tcttttttaa gagatgttga ctactgagat cccctacttg
    59761 gtaaaagtca aagaaacgat agtaaagtaa ccatcttacc taggcctaaa tacaatcacc
    59821 acccctaggt gacacacagc acctatttca aaaatgatat tagtatggca aaacaaaaag
    59881 acaacgcctt cttttttctc cttactatct cctttaattt tcatattttt taaaaaaact
    59941 attgataaac tagttaagta agcgtatact atggttagtg agcgaaatta gaaaagagga
    60001 caagcatatg aatctacttg gatcaagacg ggttttttct aaaaaatgtc ggttagtgaa
    60061 attttcaatg gtagctcttg tatcagccac aatggccgta acaacagtca cacttgaaaa
    60121 tactgcactg gcacgacaaa cacaggtctc aaatgatgtt gttctaaatg atggcgcaag
    60181 caagtaccta aacgaagcat tagcttggac attcaatgac agtcccaact attacaaaac
    60241 cttaggtact agtcagatta ctccagcact ctttcctaaa gcaggagata ttctctatag
    60301 caaattagat gagttaggaa ggacgcgtac tgctagaggt acattgactt atgccaatgt
    60361 tgaaggtagc tacggtgtta gacaatcttt cggtaaaaat caaaaccccg caggatggac
    60421 tggaaaccct aatcatgtca aatataaaat tgaatggtta aatggtctgt cttatgtcgg
    60481 agatttctgg aatagaagtc atctcattgc agatagtctc ggtggagatg cacttagagt
    60541 caatgccgtt acagggacac gtacccaaaa tgtaggaggt cgtgaccaaa aaggcggcat
    60601 gcgctatacc gaacaaagag ctcaagaatg gttagaagca aatcgtgatg gctatcttta
    60661 ttatgaagcc gctccaatct acaacgcaga cgagttgatt ccaagagctg tcgtggtatc
    60721 aatgcaatct tctgataata ccatcaacga gaaagtatta gtttacaaca cagctaatgg
    60781 ctacaccatt aattaccata acggtacacc tactcaaaaa taataccaaa aggctagacc
    60841 tctgctcact aggcctagct ttttacatca aaaaaagcaa tgactataga aagtaaaaat
    60901 actagaaaaa gcaatgattg ccgtcattgc tttttatgat ttgtcaaaaa gtaaaaagca
    60961 aattgaaaaa attgccctgg agctattgag ataaactaca ccatttatta agataccaaa
    61021 tcaaaaagct aacaccataa gagcgttagc tttttaaaga gcctcaggac agtttatgtt
    61081 taatggcttc taggtaggtt tgaaacatat gatggatcgt tttgcaatta agtaattgga
    61141 agatctccaa gatctgcaca cacttttgct cagccccctc tttaccattt atgaggccaa
    61201 taatgccatc aaaaaaagac acacaacacc gttcatataa gcaatcatca tttagctgat
    61261 aatcttcaat ttttgccaaa atctcagaag ctttatcata ctcttgtcgc tgaataaaca
    61321 aaatcaacat attgacaaac atccgaatcg attcattccc ataatacctt agggtattgt
    61381 atttatcgag gttcaaaata acttttgaaa acaccatctc aataaagcaa gactcaaaaa
    61441 taaacataca attattaaaa agcacagtct catagtgact ccaagtttca atattaataa
    61501 gatagtttga caaataagtc cgctctgtca gacagtcttc ctcagtaaga gttgctaata
    61561 acaccttgac caaggcaaaa aggttctttt cctttgttga tttactatct ttataagaat
    61621 caaggatatg atttaaacca tctatgtttc ggcattcaaa ataatgtttt gccgtatcca
    61681 tatcaataaa ttctttatat tgtttaaagt tattactaat aaagagaaac tcatcaacat
    61741 tgacattcaa gttgtctaag atataaagta actttttcga agaaatgtca agattatttt
    61801 taataaaacg ataataggtt tgcctagtga gataatcacc acaaacttgt ttaatcgaaa
    61861 tgttttttga atgcctaatg aattcaacgg tttcaccaat ttccatatgt caagccttcc
    61921 tagttgatgt caaaaatacg ttacgcatgt acctaatacg taacaagttg aatgtttcgg
    61981 atgatagtcg cttatgatag gtgcataagg tcaatagcca gatgcgatag ttttatcaac
    62041 tgtcatatgt taaacctttc taatctaata gatgttaaaa atacgttacg tgtgtaccta
    62101 atacgtaaca aaataatggg ttagcaaaat aagcagctat gatatagcca taaggttaaa
    62161 aggaggcgcc tactatgtgg ttattgttac tatttttgta gttccttttg caaaatggta
    62221 gtagataaaa atgagaagtc aataaaagca ttgacaaaca aaagaatcat tttgtttata
    62281 ttatcagtat ttttaagttt cttgtcaact gaaatgagca tctactagcc acaatagtaa
    62341 ctaaaaggct aattgtcagt aaaaatgaga taaatcagcc aggaaaaagc ctacgagtca
    62401 actaatggac aacccaaaaa aagacaaagg attttcactt ggtgttgtgg accctatcac
    62461 gatccttatc acagaatcag ttattaacaa aatgagaacg gtcccatatc atctaaaaaa
    62521 actgtcaagc acaacctatt gtttgctagc tgatcttgcc tatcagtctg cctagcagat
    62581 acggcagaag ataagagatc aaccaaaaga tgataagtgc aacgactcat agcgtctttt
    62641 gaccaaaacc aattaggctc acatgagatg agaataattg ggttgggttg tcagtgtcaa
    62701 ctaaccgtgt tattgtctat taccattcat ggtatcagcg acatcgtatg ataaccatac
    62761 gattcagcta agtaaggagg tgtgtccaat gtaccgttaa aagcaaatgc agtagattaa
    62821 cttattttga aagaggtata aaaaaaatga ataaaaagaa attaggtatc agattattaa
    62881 gtcttttagc attaggtgga tttgttcttg ctaacccagt atttgccgat caaaactttg
    62941 ctcgtaacga aaaagaagca aaagatagcg ctatcacatt tatccaaaaa tcagcagcta
    63001 tcaaagcagg tgcacgaagc gcagaagata ttaagcttga caaagttaac ttaggtggag
    63061 aactttctgg ctctaatatg tatgtttaca atatttctac tggaggattt gttatcgttt
    63121 caggagataa acgttctcca gaaattctag gatactctac cagcggatca tttgacgcta
    63181 acggtaaaga aaacattgct tccttcatgg aaagttatgt cgaacaaatc aaagaaaaca
    63241 aaaaattaga cactacttat gctggtaccg ctgagattaa acaaccagtt gttaaatctc
    63301 tccttgattc aaaaggcatt cattacaacc aaggtaaccc ttacaaccta ttgacacctg
    63361 ttattgaaaa agtaaaacca ggtgaacaat cttttgtagg tcaacatgca gctacaggat
    63421 gtgttgctac tgcaactgct caaattatga aatatcataa ttaccctaac aaagggttga
    63481 aagactacac ttacacacta agctcaaata acccatattt caaccatcct aagaacttgt
    63541 ttgcagctat ctctactaga caatacaact ggaacaacat cctacctact tatagcggaa
    63601 gagaatctaa cgttcaaaaa atggcgattt cagaattgat ggctgatgtt ggtatttcag
    63661 tagacatgga ttatggtcca tctagtggtt ctgcaggtag ctctcgtgtt caaagagcct
    63721 tgaaagaaaa ctttggctac aaccaatctg ttcaccaaat taaccgtagc gactttagca
    63781 aacaagattg ggaagcacaa attgacaaag aattatctca aaaccaacca gtatactacc
    63841 aaggtgtcgg taaagtaggc ggacatgcct ttgttatcga tggtgctgac ggacgtaact
    63901 tctaccatgt taactggggt tggggtggag tctctgacgg cttcttccgt cttgacgcac
    63961 taaacccttc agctcttggt actggtggcg gcgcaggcgg cttcaacggt taccaaagtg
    64021 ctgttgtagg catcaaacct tagtatggaa atgcatttcg ttagaacaga acctgaggca
    64081 cgccgcatag ctgaaacctt ttgtgccgaa aacacacaaa caaaaacccc tatgcgcgtg
    64141 cagcagttaa gctatccatc agacacagat cactcaggtg gtgagctata catctatgct
    64201 ttgtctcctg ctggatttat catcgtatca ggagacacca gagcgcacac cattttaggc
    64261 tattcttttg ataataacct ggacctcaac catgataatg tcagaagtat ggtagaagct
    64321 taccaaaaac aaatcaactc tttggattga tcggtcaaag tagcttttgc cccctcacca
    64381 ctcgtttaag acgaccgtgt ttctaaaata ccactacctt ttaagtttca cgccggccta
    64441 agcaagtgtt tgtctcatgg agcagactgt ttccatcgaa aagtcaccca ttgataaagg
    64501 aggtcatcaa cgcctactaa tgatgacttc cctaagatgc caaggtaaag gactgagttc
    64561 tgtagagatg ggactcagtc cttttacgat ttttgggagt tattctagcc ataccgtggc
    64621 aagaaaacaa cactcaaaaa tagccaacgt cagtttctgt tcatacatga ctacagccaa
    64681 acaccacaac ctaacctatc ctaaacacag tggctttcta acgaacagtc acaacgagca
    64741 gcaacaccaa aaagcaagat taagctacgt ttaagactaa tgatataaga taacagtaat
    64801 tattaatgag aaaagaggct caaaaggaca tgaaacaaat gaataaactc attacaggag
    64861 tggtaacgct ggcgacagtc gtgaccttat cagcttgtca atcatcacac aacaacacca
    64921 aactcgtctc gatgaaagga gacaccatca ctgtcagtga cttctacaat gagaccaaaa
    64981 acacagaact cgcacaaaaa gccatgttaa gcttggtgat tagccgtgta tttgagacac
    65041 aatatgccaa caaagtctct gacaaagagg ttgaaaaagc ctataaacaa accgcagacc
    65101 aatacggtac ctcctttaag acagtcctag cacaatcagg cttaacgcca gaaacctata
    65161 aaaaacaaat tcgcctcaca aaattagtcg aatatgccgt caaagaacaa gccaaaaacg
    65221 aaaccatctc aaaaaaagac taccgtcagg cctatgacgc ttatacccca accatgacca
    65281 cagaaatcat gcagtttgaa aaagaagagg atgccaaagc agcccttgaa gccgtcaaag
    65341 ctgaaggggc agactttgca gctattgcca aagaaaaaac cattgcagcc gataaaaaaa
    65401 taacctacac gtttgactca ggcgaaacaa ccctaccagc agaagtagtt agagctgcat
    65461 caggcctcaa agaagggaac agatcagaaa tcatcacagc gcttgatcca gccacctcaa
    65521 aacgcaccta ccatatcatc aaagtcacca aaaaagcaac taaaaaagca gactggaaag
    65581 cgtaccaaaa acgcttgaaa gacatcattg tgactggcaa attaaaagac cctgacttcc
    65641 aaaacaaagt catcgctaaa gctcttgata aagcaaatgt caaaatcaaa gacaaagcat
    65701 ttgccaatat cttagcccag tttgcaaaac ctaaccaaaa acaacctgcc caaaaataga
    65761 aggttgccag tttatttccc taaggttgct taaaaagaca gccctagcca tcactcccct
    65821 tttcaaaaca ccgataatgg aaacgtgtcc tatactgatg gtctagggca atgtcataaa
    65881 gctaaagact ctatccaaat aaggatagag tctttaatgt tttaaaacca gtcagcaaaa
    65941 aaattcacgc taagcctaga atgaggctta gcgtgaatgg tatcagtgat agtccgttaa
    66001 actagctgat tgggagtcag aaactctcct tacccaatct gactataccc ccagtaccag
    66061 aggcgtctca tcgcagaagt agtaatcaga taatcgtctg ataagctctt gtcctcaagc
    66121 aactgatgag tatcgtcgca cgggccatga gctgtcggtg gctgatagct agtaggctca
    66181 tcagccaaaa cttttttgga gtaacgcttt ggtctcagac ggcgccagag ggttgagaga
    66241 ggggtgagaa aaaaacgatg ggtcatcttg gcctccttgt ctaatgatag tcaccttaac
    66301 agacaaaagt gtcaataatg ttattttaag gagaaaaaga ttaaaaatca aggtcacaaa
    66361 ctttcctttg ttaaaaaaac gcgaccctaa taaagactct aaatacccct cgcatttgag
    66421 cttctccttg cgcagctatc tgcgcactca gttgcctcca agctaatgat agcgatacca
    66481 ttattgtcct ataggctatc gcggcaaccc ctttttttcg tctcaacgag tctgacacag
    66541 ctgtcatgac agagaaaaga ctcttgtcta tctaagagat cattaatttt tctctcacca
    66601 aaaaactgat tttgggaaca aaaaagtatg gtgtataata agtttcggaa caattatgac
    66661 ataataatga aagtaaggtt aacgaaacat tgacaaattg taagtataaa cttagaaagt
    66721 tatctgtagg gctcgtctcc gttggaacga tgctgatagc cccgacagtt ttaggacagg
    66781 aggttagtaa tactgaggct agtgctagta gtaccgctag cgtagacgct acggcaagtg
    66841 ggacgactgc cagcggagct agtagtgaag caaccgtagc tactaccaat ggaggaagtc
    66901 agtctactca agtagcagct gaaacgactc cacaacctca agtacagact tcagaacaac
    66961 cagcagctac atccacatca ttggcttctt ctactagtag tagtgaagat aaagctccta
    67021 aggcagcaag cactaaatca tcttcagcaa ctgtggctag ctctagtaat ggtagcaatc
    67081 aaggtgctgg tactgaagtt gaaccacaga tgatggacgt ggaacagtat aaggttaata
    67141 aggaaaaaac agagcttact gttaaagatg acaaccagca gctcaagatc cgtaaagatg
    67201 ttgatgaatt aaaaaataaa gatctttttg atgtcaaacg tgaagtgaaa gataatggcg
    67261 acggaacctt agatgtaacc ttaaaagtaa cacctaaaca aattgacgaa ggtgccgatg
    67321 ttatggccct tttagacgtc tctcaaaaga tgacagatgc tgattttaac aacgctaagg
    67381 aaaaaatcaa gaaattagtc aaaaccttaa cgagtaaacc tactgatagt catccaaacc
    67441 ataatgctcg caactctgtg cgcctaatga ccttttaccg tgaggttagt gacccaattg
    67501 atatatcagg aaagacggat gaggaactca ataagatatt agacgatgtg tggcaaaatg
    67561 ctaaacataa ttgggactgg ggggttgact tgcaaggagc tatccataag gctcgaggga
    67621 tttttaagca agaccaagaa aaaaaatcgg gtaaacgcca gcatatcgtc ttgttctctc
    67681 aaggtgagtc gacttttagt tatgatattc aaaagagtga gaaagagaga gacaacaatt
    67741 tatctcgtat aaatgaaaaa attacctctt ctaacccttt gttacattgg ccacctattt
    67801 ttaaccacac gcatcaaaat gcagatatgt taaatgaaat cgaaaggatt ataaagatag
    67861 gggagcaact aggtataaaa ggcctttcta gtataaaagg gtatttaagt acggcagcag
    67921 caggtagcgg gattctggga aattttatcg gtggaggaag tcttacagaa tacttaactc
    67981 ttaaagaata taactctgat aaattagaag aaagccaatt tgattacacc aaacgtgtgg
    68041 gcgagggata ctattattat agcttctcaa aaagagtaag tcacaacgat ttccctttta
    68101 aaactttaat agagcaggct atcacacaag cgattcctac taagggtgaa agtaaaaatt
    68161 ggttcgagaa atttttagat aaattttcat tggtggaaag ttatcgagac actcaaaaaa
    68221 aagcattatt aaagattctt gaatatcttt tttataagcg tgaataccac tactataatc
    68281 acaatctttc agcgatagct gaagccaaaa tggctcaaca agaaggcatc accttctact
    68341 ccgttgatgt tactgattca gaaacaactc ctaaaagagt gaggcgacaa acagcagtac
    68401 gtcaggaaaa agcgaaaaaa gaatccaaag aagagcgcaa tgaaaagttt gataaatatc
    68461 tgaaaaagat gtctgaaggt aatactttct tagatagtgt tgaagagaaa gataagttca
    68521 aagacacctt caccaatgta acagtgacag aaaccttcga agataaggtt tccgctatag
    68581 caaattcttg ggaatcttcg ctagatagtc ataataacaa atcagacaga aatcataaag
    68641 gaagtgtcaa acatacacaa gctcaaagca gcggatggtt tgccaatacc caagaaagcc
    68701 tcacttggac tatttccaaa gaccagctca aaaaagcctt tgaagatgga gaaccgctaa
    68761 ccctcaccta taagcttaaa gttgataaag ataaatttag agaaactctt aaaaaacaac
    68821 aagaacgtaa tagaaaaaac gagcagcatc tccggaaagt gagaacactg tcacagaaaa
    68881 aattatttca aataagattt cttacaagat taataatggt aaggatataa ataacaataa
    68941 gttggaagat gttaaaatgt cttacagcaa gttcaaaatg cctataccag aacttgatat
    69001 agaagttgta ccaataccag aaaaaccact ggtagaacca atgacgcctc tatatcctgc
    69061 aattcctaat taccctaccc ctcaacttcc aaaagatgaa gatctggaga ttagtggagg
    69121 tcatggaccg attgtcgata tcgtcgaaga tactggtaca ggtgttgagg gcggctctca
    69181 aaacggcgtg gtttcaactc aggaaaataa agatccaatc gttgacatca ccgaagatac
    69241 ccaaccaggc atgtcaggct caaatgacgc gacagttgtc gaggaagaca cagcacctaa
    69301 acgtccagat gtccttgttg gtggtcaaag tgatccaatc gatatcaccg aagataccca
    69361 accaagtgtg tcaggctcaa atgacgcgac agttgtcgag gaagacacag cacctaaacg
    69421 tccagatatc cttgttggcg gtcaaagtga tccaatcgat atcaccgaag atacccaacc
    69481 aggcatgtca ggctcaaatg acgctactgt tatcgaagaa gatacgaaac caaaacgctt
    69541 cttccacttt gataacgagc cacaagcacc agaaaaaccc aaagagcaac caagtaacag
    69601 cttaccacaa gctccagtct ataaggcagc tcatcacttg cctgcatctg gagacaaacg
    69661 tgaagcatcc tttacaattg ttgctctaac aattattgga gctgcaggtt tgctcagcaa
    69721 aaaacgtcgc gacaccgaag aaaactaacc ctcgttagtc tagcgaccct aagcctttgg
    69781 ctttaaaaat ttctcattat ccccctcaaa caccggtacc tcactgagat ggcgcttaaa
    69841 aaagccgcta gtcttaaatc aggtatcccc tacggttgag ggggattaat gggtatcaca
    69901 acaagtaaaa aggtataatg atgaaatatg actaaaaaat ttattaaatc agcagtgatt
    69961 ctaggcttag caagcataac catcagcatg acgcaacccg ttgaagccat ttcaaatagt
    70021 ttagaatatc aagcacaata taaacgtgtc aaagaagaac tagacgcatt aaaagaaaag
    70081 ggcccaaaat taggggaacg ttccctttat tttaaagtgg tgaatagatt tctaggttgg
    70141 tttggcgtag tctgggaccc actcgcaatc aaagaaaccg atcacctgtt ggacctcatc
    70201 ggacaagtca attacttggt gagtaacacc gagtttcaag cccctgagta tcaaaaggct
    70261 aaaaacaaac tagacttagc tgtagcaggc tatgacctct acctagctag agagaaaaaa
    70321 cgtggtgatg ctcctgatta ccaagtgacc cagctaacgc taggacagct cgaaaccatc
    70381 aaaacgaaga tacaagaggc cctgaaaaca tttgcacaag aggtcaaaac gatccagcaa
    70441 aaaaaaccag acctatttcc ccatgcttat gttttaaacg ctaagagcaa agatatcaca
    70501 gataaagcgc aacccttttt agtgaatggt tactacgatg tcttttataa gcagttttta
    70561 ttcactaata caaatgacgg ctacaactat aataaagaag cagacaatct ggcttcgtat
    70621 caaaagctga ttaaagagct attaggctta aaagctgaga tcgatcagtt aacaaaagac
    70681 gatcctaaaa acgatcgttt agagacgtta atgtgggaat caaagttcac cttatctgat
    70741 tcacggagaa cttcacgcct tagcgcctac tatacacaag aagattatgt caaaaaggtg
    70801 gtcctatctg aagaagctcc caacttgaga acagcaaaag aaaaggtcaa gaccttaaaa
    70861 gggatcttgc atgattacta tgttgacatt aaagagccag aaaaagctaa aaagtatcgt
    70921 gtcgaggacg agaccttgcc gtctcaacct gaggcccctg ctaaacctga agctcctgct
    70981 cctagtccta gtcctgctcc tggtcaaaaa ccagcagaag atgagagatc atcacaagct
    71041 acggagccag ctaacccgtc aaaagagaat tcctcaacgg acgcatctca gggatctcac
    71101 gatagtgaaa acccagcgac agacagtcct tctcaacctc aggcatcaga ccaaggcaat
    71161 caccaaagcc aagtgcctaa cgccaagcct caaacggaca agacggacac tcctaacgcc
    71221 ccagtccctc cacagaacac tcctaacgcc ccagccatcc cacaggacac cccaaaagtt
    71281 cctgaggctg gtggtcagag tggccccgct gggaacgctg aggagaaagc tcctgactct
    71341 ggacctaaag agtctggtca aagctcatct aaagagtccc catccgttgg cgaagacacg
    71401 acccctaatc agccagacgt ccttgtaggt ggtcaacgtg agccaattga tatcaccgaa
    71461 gacacaatca ctgacgctcc tccgacagta tctgggcaca acgcatcaac acagccccaa
    71521 tctgtggtcg aagatacagc acctcagcgc ccagatgtcc ttgtaggtgg tcaaagcgag
    71581 ccaatcgata tcacccaaga tacccaaccg ggcatgtcag gctctaatga cgctaccgtt
    71641 atcaatgaag atacaaaacc aaaacgcgtc ttccactttg ataacaaaga gccacaagca
    71701 tcagaaaaag cggcagagca aaaacttgct cctcatgata gccacacaac ccctcaaact
    71761 tcagatgata cagcagcccc tcacttgcct gcatctggag acaagcctga aaaagtgttt
    71821 gcacttgctg ccttgacaat ggtcgcagct gcagggctac tcagcaaaaa acgtcgcaac
    71881 accgacaaaa actagtcgct gttagacaca acgcatcact aaggccagtg catttgcact
    71941 ggccttagtt aggtttttat caaatagagg gtttttcatg acaattgcta gcatttcggt
    72001 gtaaaataaa ggtaataatc agcaaaggag caacccatga caaagcaaga tcagttaatc
    72061 gttgaaaaaa tggaacaaac ctatgaggcc tttagcccaa agctagcaaa tctcatagaa
    72121 gccctagatg cctttaaaga gcattatgag gaatatgcca cacttagaaa tttttacagt
    72181 agtgacgaat ggtttcggct tgcaaaccaa ccttgggatg atatcccgtg cggtgtccta
    72241 tctgaagacc tcctctttga tatgatcggt gaccataacc aactactagc tgatatctta
    72301 gacttggccc ctatcatgta caagcatatg taatcatcgc taacgtcaca gatactacga
    72361 tgataggaca aaaaaagctt gaaaatctca aaaaaaacag ataaaaaaca gataatcgtt
    72421 agaaaaacag tagatgcgtc tgttaaacta aaggtatcaa aacaaaagga gcatttcatc
    72481 atgaaattca aaaaagtatt agtcattcct gcattagcat tagcagcaac atgcttttta
    72541 acagcttgtg gcacaaagaa agattctaaa aaagaagaag ttaaagaaat caaaatgtct
    72601 gacatcaaag acgacgcagt tagcaaaaaa acaaaagtgg ttgatggcga agaagttaca
    72661 gaatacacca caaaagatgg aaacgtgatt cagattcctg caggaaacga agaaggcatg
    72721 gaatcaaaag atgctggtgg atcaggcgct cctgctaaaa actaagggtt acaacaaaga
    72781 gcataaggtg actcgcaaac gttacgcatg acatgaggca gtctgcctaa gatggtaact
    72841 cacttatcat aatgcctaaa tagccaaaca cactaactcg caaatgtaca aaatcatata
    72901 cccgtgctta tgtgagcgaa cggttatatg atttttgttt tccaaaaaca agaaaagaac
    72961 gctaaaatag ccagtttgtc gtgtttcaag ctacgaaaaa ggaagtgcta aaatgaaaaa
    73021 aagatccatt atacctgtca tcttactgtt ggtcatcgga ttaatcgttg gtgttaagcg
    73081 tcatcatgac tagtaggtct tgctagtgac cgttcaaaag ggataacgtt ggtatggtat
    73141 aaccataaaa atcgtataaa aagaaaaaat agctattgag gagaaagtat gtttcagtta
    73201 agaaaaaaaa tgacgcgcaa acaattagcc ttgttgagtg ctggagtgtt gacctgtgtg
    73261 gttggtggta cctacttgat aatgaatcat caacaacaag aaattgtctc tagtgtcaac
    73321 aaagtaaaag ccttaaccat aaaagaggcc atggaacaag gaaaagatat cagcttgacc
    73381 ttagctggcg aagtaaccgc taacaacagc agcaaagtca aaatcgactc aagtaaagga
    73441 gaagtcaaag atgtctttgt caaaaaaggc gatgttgtca aagtaggaca acccttgttt
    73501 agctatgaaa cgtcacaacg gttaacggct caaagttcag aatttgatgt tcaaaccaaa
    73561 gccaatcaac tccaagttgc taaaaccaat gcagcattga agtgggaaac ctacaatcgc
    73621 aaggtcaatg agatcaatac cctaaaatct cgctacaaca ctgcaccaga tgagagctta
    73681 ctagagcaaa ttcgcagcgc agaagacagt gtatcccaag cactaagcga tgccaaaaca
    73741 gcagatagcg atgtcaaaac cgctcaaatc gaactcgata aagctaatgc tactgccaca
    73801 atggaaaaag gtaaactaga gtatgacacc gttaagtcgg acaccgcagg aaccattgtt
    73861 agcctaaata ctgatttgcc aaatcaatca aaatccaaaa aagaaaatga aacttttatg
    73921 gaaattatcg acaaatcaaa aatgttagtc aaaggtaaca tcagtgaatt tgaccgtgac
    73981 aagttaaaaa tcggtcaaaa agtcgaagtg attgaccgca aagacaactc taaaaaatgg
    74041 actggaaaag taacccaagt tggcaacctc aaagcagagg aaaaaggcca aggtcaaggc
    74101 caaggtggca atgaccaaca agacaatcca aaccaagcaa aattccctta tgttattgaa
    74161 cttgaccaat cagacaagca gccactcatt ggctcacaca cctatgttaa tgtgctcaac
    74221 aatgttccag aagctggcaa gatcgtattg aaagaaacct ttacaatggc agaaaatgga
    74281 aaaacctatg tgtggaaagt tgataaaaac aaggtcaaaa aacaagaagt caagactaag
    74341 cccttctcaa aaggttatat tgaggtgaca agtggcttga ctatgcaaga taagattgct
    74401 cagccgcttc ctggcatgaa agatggtatg gaggtaggaa gtattgttaa accttaaaga
    74461 tattcgaaaa agctatcatc ttgggactga agaatttgcg attttaaaag gaatcgattt
    74521 agaagttaac gagggtgact ttttagccat catgggacca tcaggttcgg gaaagtcaac
    74581 attgatgaat atcattgggt gtttagataa gcctggctct ggctcatatg ccattgaagg
    74641 cagagacgtg tcatccttat ctgataatga acttgctgat ttgcgtaatc aaaaaatcgg
    74701 ctttgttttt caaaacttta acctgatgcc caagctaaca gcttgtcaaa atgtcgaatt
    74761 gcccttgact tatatgaatg ttcctaaaaa agagcgtcgc aaacgagccc tagagatgtt
    74821 aaaactagta ggactagaag aacgtagtga atttaaaccg atggagctat ctggtgggca
    74881 aaaacagcgt gtagcgattg caagagcttt agtcactaat ccgagtttta tccttggtga
    74941 tgagccaaca ggtgcactag acacaaaaac cagcgtccaa atcatggacc tatttaaaca
    75001 attcaatgat aacggcaaaa cgattattat catcacacac gagcctgaag tagctgcctt
    75061 atgcaaaaag acggtgatcc taagagatgg taatatagaa cattccgata tagagtaaag
    75121 ggggaaaata atggaagata ttattgcagc tttaggctct atattatcac acaagatgcg
    75181 gtcaattttg acaatgctag ggattattat cggtattggt gccattatcg caatcttttc
    75241 aatcatcgaa ggtaataccg aaaataccaa aagacagttg attggtggca gcaataacac
    75301 tattaacatt gtgtttaaca aaaaaagcag tattgatcct aaatttccag ataagtcaaa
    75361 tgctaaaaaa ccagactatc ttccttttat ggctgaagaa gagcttagca aaatacagca
    75421 agtcaaaggc gtcaaaaacg ccctgatctc atatggtatt gatgacaaag tctaccatct
    75481 aggccaaaaa tcatctgcaa agatttctgc catcacaaaa aacgtagctg aagtgagacg
    75541 catgacattt attaaaggca gtgacttttc agacaaagac tttattgacc aaaaacaggt
    75601 gatttacctt gaaaaaagct tgtatgagtc gctatttcca aaagacgatg gtcttggaaa
    75661 atttgtcgaa gtgatgggaa atcccttcag ggtcattggg gtgtttgaat caaaagaaca
    75721 aagtggcctc acaagtggga ctgagaaaat tgcttatatc ccgctacatc agtggtataa
    75781 tattaatggt gtagtggatg cgacacctga gatcacgatc cagacctatc gcgcagatga
    75841 cctcaaacct gtggcaaagc gtgtcagtga tatgctcaat caaacgatcc ctaaatcaga
    75901 ttatatgttt ggtgtcatga accttaaaga atttgaacgc caactagaca acctaaacaa
    75961 atctaatttt gtgttattag ctggtattgc tagcatctct cttattgtag gtggtattgg
    76021 tgtgatgaac attatgctag tatcagttac cgaaagaacg agagaaattg ggatcaaaaa
    76081 agcgcttggc gctagacgta agcttatttt aaaacaattt ttaattgaag cggtcattct
    76141 aaccttgcta ggtggtgtga taggggttat ttcagggatg gtatcaggat tgatcatcac
    76201 aagatcactc gagtatccct atatcctatc cttgttctca gttgtcttga gtttagcgtt
    76261 ttgttgtatt atagggattg tctttggact attaccagcc attaaagcgt ctaagctaga
    76321 cccaattgaa gcattgcgat ttgaataatc aaccaaacaa gcataaaagt caaaaaggat
    76381 gaccctttga tgtcatcctt agctgcttga tacactaaac gccaatctag aaagggaagt
    76441 tatgtttaaa atattagtag ttgaagatga tgataccatc agtcaagtga tttgtgagtt
    76501 tttaaaagcg aataactatg atccagattg tgtatttgat ggccaagctg ccttagacaa
    76561 gtggcagaca acgtcttatg atctgattat tttagacatc atgctccctt ccttaagtgg
    76621 cttagaagtg ctaaaaacaa ttcgaaagac atcagatgtc cctattatta tgctaacggc
    76681 attagatgac gagtacacac agcttgtaag cttcaaccat ttgattagtg attatgtgac
    76741 taaaccattt tcaccactca ttttaatcaa acgtatcgaa aatgtattac gcgtctctac
    76801 tccagatgaa aagcgccaaa tcggagactt acttgttgat gagaccgaac atagcgtcta
    76861 ttggcaagga acattggtca aactaaccaa aaaagaatat gacattattg attatttagc
    76921 aaaacgtcac caaaagattg tcaccagaga ccaattgatg gatgacatat ggggctattc
    76981 tgaactggac acgcgtgtcc ttgacaacca catcaagaac cttcgtaaaa aaatgacggg
    77041 tattcccctc aagacaatta caggcatggg ctatttattg ggagagcgtg agtgagacta
    77101 atcaaaaaaa cctttttggt catcaatggc ttaattattg tagtggttac ctctattttg
    77161 ttagtgcttt attttgcaat gccaatttat tacaccaaag tcaaagacaa agaagttaag
    77221 cgtgaatttg accaaacaag caagcaaatc aaaggcaaga cggtaaccga gattagagat
    77281 atcctaacaa aaaaaatcaa caaagataat atttggtaca gcttagtaga cagtgataac
    77341 caactgctct atccttcctt gcaactgtta gacggcgtca gtgaaagcaa agacagtcaa
    77401 aatgttaata tcgtcaccac ctttgacaac tcttattcta atgttaaggt gatgagtcaa
    77461 aaagtaaccc tacgcgatgg aaaaaaaatg acattgcttg ggcaatcttc acttcaaccc
    77521 gtaacagatg ctagcaaagt tctccttgac ctctacccgt cactattgat tttttcagtg
    77581 actgtaggga gtattgtcgc ctacttatat agtaggactt ctagccggcg tatccttagc
    77641 atgtcacaaa ccgccaaaaa aatggtcaac ctagaaccaa acttaacgtg taccattcac
    77701 ggcaaagatg aaatagcaat gttggctagt gatattaacc gtttgtatgc gagtctttca
    77761 acgagcatca aatccttgca aaaagagtat gaaaaagctt ctgattcaga aagagagaaa
    77821 tctgagtttt tacgcatgac atcgcacgag ctaaagacac caatcaccag tgttatcgga
    77881 atgattgatg gaatgctcta taatgttggt gactttgcag atcgtgacaa atatttgcga
    77941 aaatgccgag acgtccttga agggcaagcc caactggttc aatccatttt atctttatct
    78001 aagattgaaa ccctagcttc tcaaaatcaa gaactgtttt cactaaaaag cagcctagaa
    78061 gaagaaatgg aagtctttct cgtcttatca gaactaaaac acctcaaagt gactatcaat
    78121 ctcgaagaac aattcgtcaa agccaataaa gtatacctac taaaggcaat taaaaatatt
    78181 attgacaatg cctttcacta taccaaacca ggcggccaag tgatgattca actaaaagac
    78241 aaccaactag tgattaaaaa tgaagcagag acattattga cacaacagca gatgaaacag
    78301 ttattccaac cgttttatcg accagattat agtcgtaaca ggaaagacgg tggtacagga
    78361 ttggggctgt ttatcaccca ccagattctt gatcagcatc atctggctta tcgctttgtt
    78421 gttcttgatc aaagatggat ggtatttacg attgattttc catcccatca tgacgattga
    78481 tccacactag taggacgaca aaagtcatca atcactaacc aagccttgac ctttacccat
    78541 cattatttag gcaagtataa aaaagaggag agaaatcata tatgaagaaa aggaaattgt
    78601 tagcagtaac actattaagt accatactct taaacagtgc agtgccatta gttgttgctg
    78661 acacctcctt gcgtaataac acatcatcca ctgatcagcc tactacagca gatactgata
    78721 cggatgacga gagtgaaaca gcaaaaaaag acaaaaaaag caaggaaaca gcgtcgcagc
    78781 acgacaccca aaaagaccat aagtcatcac acactcaccc aacccctcct tcaaatgata
    78841 ctaagcagac cgatcaggca tcatctgaag ctactgacaa accaaataaa gacaaaaacg
    78901 tcaccaagca accagacagc agtgatcaat ccaccccatc tcccaaagac cagtcgtctc
    78961 aaaaagagtc acaaaacaaa gatggccgac ctaccccatc acctgatcag caaaaagatc
    79021 agacacctga taaaacacca gaaaaatcag ctgataaaac ccctgaaaaa ggaccagaaa
    79081 aagcaactga aaaaacccca gagccaaatc gtgacgctcc aaaacccatc caacctcctt
    79141 tagcagcagc agctcctgtc tttgcaccgt ggagagaaag tgacaaagac ctgagcaagc
    79201 taaaaccaag cagtcgctca tcagcggctt acgtgagaca ctggacaggt gactctgcct
    79261 acactcacaa cctgttgtca cgccgttatg ggatcactgc tgaacagcta gatggttttt
    79321 tgaacagtct aggtattcac tatgataaag aacgcttaaa cgggaagcgt ttattagaat
    79381 gggaaaaact aacaggacta gacgttcgag ctatcgtagc tattgcaatg gcagaaagct
    79441 cactaggtac tcagggagtt gctaaagaaa aaggggccaa tatgtttggt tatggcgcct
    79501 ttgacttcaa cccaaacaat gccaaaaaat acagcgatga agttgctatt cgtcacatgg
    79561 tagaagacac catcattgcc aacaaaaacc aaacctttga aagacaagac ctcaaagcaa
    79621 aaaaatggtc actaggccag ttggatacct tgattgatgg tggggtttac tttacagata
    79681 caagtggcag tgggcaaaga cgagcagata tcatgaccaa actagaccaa tggatagatg
    79741 atcatggaag cacacctgag attccagaac atctcaagat aacttccggg acacaattta
    79801 gcgaagtgcc cgtaggttat aaaagaagtc agccacaaaa cgttttgacc tacaagtcag
    79861 agacctacag ctttggccaa tgcacttggt acgcctataa tcgtgtcaaa gagttaggtt
    79921 atcaagtcga caggtacatg ggtaacggtg gcgactggca gcgcaaacca ggctttgtga
    79981 ccacccataa acctaaagtg ggctatgtcg tctcatttgc accaggccaa gcaggagcag
    80041 atgcaaccta tggtcacgtt gctgttgtag agcaaatcaa agaagatggt tctatcttaa
    80101 tttcagagtc aaatgttatg ggactaggca ccatttccta tcggacgttc acagctgagc
    80161 aggctagttt gttgacctat gtcgtagggg gcaaactccc aagaccataa ccccacaacc
    80221 aagaagctac ctgcctgttg accaatctca aaaagagata gcgtcaactt agaatgaggt
    80281 tcatcagatg ataaagaaag tgactacccc gagtcaaaaa acaaaaaaac gtgttcgtaa
    80341 tggctatctc ctaaaactag gtacagcctg tttactctta agtatactca gttatggcat
    80401 tggtcttttg ggccagccta gcatggaaaa tacgtttatg ggaatagcga gtgttgccat
    80461 gttaggaagt gtctgtttct ttattatctt tgctctaaac cgtatctttg acgcactaga
    80521 ggacaatttg cgagattaga gtaataggtc aaataatctt ccaataattt agagcacaag
    80581 ctaagttatt ggaagttttt ttgtcttttg agagccatga tgccatcaaa aagtcaaaca
    80641 ctccttatga tgtgagagtc acatggctaa aattaaaagc aaaatagacc ccaaagccct
    80701 gttttctcaa aacagccaac gaaaaaagac aagttaacca gttcataaaa aacatcgtag
    80761 aaacgttttc aagagctaat gttggagtaa attgactgaa gtatgataga atttttaatg
    80821 gttgtaccat gacagtcaaa cttaaaaact gaaatcagac aaaaacatta aattgcatgt
    80881 aaaaaatcta attaagttag tgacaaaata taaattaggt tcaaaaaata taaaaaaaat
    80941 ataaattaag acctatttta aaacaaaaag agcataaatg gcataaaaaa tgggtaaaaa
    81001 tccaattttt gggtcatact ttataacatt tttataaagt atgacccaaa aagaaataaa
    81061 tgcgtgatcg tgactgtttt ttggatttta atgaaagaat ttgaaaggca ttttatggta
    81121 tactttttct tgatataggt cgtgctgact taatgaaata cctcacgaaa taacaagaaa
    81181 atcaagaaaa ttaaaaagaa gggtatacaa ggtaatgtat gtaagtaagt tgtttacaag
    81241 tcaacagtgg agagaactaa aattaatctc atacgtaaca gaaaacgctg acgccattgg
    81301 cgtcaaagat aaagaactca gcaaagctct caacatctcc atgttaacat tgcaaacatg
    81361 tctcactaac atgcaattta tgaaggaagt gggaggaatt acctataaaa atggttatat
    81421 tacaatctgg taccatcaac attgcggttt gcaagaagtc tatcagaaag ctctgagaca
    81481 ctctcaatca tttaaattgc tggagaccct ttttttcaga gacttcaact ctttggaaga
    81541 attagctgaa gagctctttg tgagcctttc aacactcaag cgtctcatca aaaaaaccaa
    81601 tgcctatttg acgcatacct ttggtattac tattttaact agtcccgtac aagtatcagg
    81661 agatgaacac cagattcgac tattttacct caagtatttt tcggaagcct ataaaatctc
    81721 agagtggcct tttggggaaa tgctaaactt aaagaactgt gagcggctac tcagtttaat
    81781 gataaaagag gtcgatgtga gggttaattt tacgttattt cagcacctaa aaatactaag
    81841 ctcagttaac ttgattcgct attacaaggg atactctgcc gtctacgaca acaaaaaaac
    81901 cagtcaccgt ttttctcagc tcatccaatc atccttagaa atccaagacc tttcacgctt
    81961 attttacctc aaatttggac tatacctaga tgagactacc atagctgaga tgttctctaa
    82021 tcacgttaat gaccaattag aaatcggtta tgcgtttgat agcatcaaac aagactcacc
    82081 aacgggctgt cgaaaagtga ccaactgggt tcatctcctt gatgagttag aaatcaggct
    82141 gaatctcagc gtcaccaaca aatacgaagt agctgtcatc cttcataaca ctaccgtctt
    82201 gaaagaagaa gatatcaccg ctaattacct gttcttcgat tacaaaaaaa gttacctcaa
    82261 cttttacaag caagaacacc ctcatcttta taaagcatgt gtagcaggtg tagaaaaact
    82321 gatgcgttca gagaaagaac ctatcagcaa agagttgact aaccagttga tctacgcctt
    82381 tttcatcact tgggaaaata gtttcctaaa agtaaatcaa aaagatgaaa aaattcgtct
    82441 tctggtgatt gaaagaagtt ttaacagtgt tggtaatttc ctaaaaaagt acatcggaga
    82501 gttttttagc atcacaaact tcaatgagct agatgctctg actatcgatc tagaagagat
    82561 tgaaaaacag tacgatgtga tcgtgacaga tgttatggta ggaaaaagcg atgagctaga
    82621 aattttcttt ttctacaaaa tgattccaga agcgattatt gataagctca atgcgttttt
    82681 aaacatcagc tttgcagaca gcttgccact agacaagccc atcaagaacc ccttggactt
    82741 tcatcgcaaa gaggttatct tacccactcc ccccaacaag ttgcatgccc ccctccacaa
    82801 tttagacagc ctaaccgcag caactcaaaa acagattcat cattaatagc atttaggtca
    82861 aaaaggtggc aaaagctaaa aaagctggtc tttacctttt ggcttatatt atttacaata
    82921 gaattattag agttaaaccc tgaaaatgag ggttttttcc taaaaaatga taacataagg
    82981 agcataaaca tggctaaaaa taccacgaat agacactatt cgcttagaaa attaaaaaca
    83041 ggaacggctt cagtagcggt tgctttaaca gtcgtaggag cagggttagt agcagggcag
    83101 acagtaagag cagatcatag tgatttagtc gcagaaaaac aacgtttaga agatttagga
    83161 caaaaatttg aaagactgaa acagcgttca gaactctacc ttcagcaata ctatgataat
    83221 aaatcaaatg gatataaagg tgactggtat gtacaacagt taaaaatgtt aaatcgtgac
    83281 ttggaacaag cgtataatga gcttagcgga gaagcacata aagatgcctt agggaaactg
    83341 ggaattgata acgctgacct aaaagctaaa attactgaac tggaaaaatc tgttgaagag
    83401 aaaaatgatg ttttatctca aattaaaaag gaactcgaag aagcagaaaa agatatacaa
    83461 tttggacgtg aagtgcacgc agctgatctt ttaaggcata aacaagaaat tgctgaaaaa
    83521 gaaaacgtta tatctaagct caatggggag ctgcaaccac ttaaacaaaa agtggatgag
    83581 acggatcgta atctgcaaca agaaaaacaa aaagttttaa gtttagagca acagctagct
    83641 gtcactaaag aaaatgctaa gaaagatttc gaattggctg cattaggcca tcaacttgca
    83701 gacaaagaat ataatgctaa aattgctgaa cttgagtcaa aattggcaga tgctaagaaa
    83761 gattttgaac tagcagcatt aggtcaccaa catgctcata atgagtatca agcaaaacta
    83821 gcagaaaaag atggacaaat caaacaacta gaagagcaaa aacaaatcct agatgctagc
    83881 cgtaaaggta cagcacgaga ccttgaagct gttcgccaag ctaaaaaagc tacggaagct
    83941 gaattaaaca acctcaaagc agagcttgca aaagttacag aacaaaaaca aatcttagat
    84001 gctagccgta aaggtacagc acgagatctt gaagcagttc gcaaagcaaa agcacaagtt
    84061 gaagctgctc tcaaacaact tgaagaacaa aacaaaattt cagaagcaag ccgcaaaggt
    84121 cttcgtcgtg acttggacgc atcacgtgaa gctaagaaac aggttgaaaa agatttagca
    84181 aacttgactg ctgaacttga taaggttaaa gaagaaaaac aaatctcaga cgcaagccgt
    84241 caaggccttc gtcgtgactt ggatgcatca cgtgaagcta aaaaacaagt tgaaaaagct
    84301 ttagaagaag caaacagcaa attagctgct cttgaaaaac ttaacaaaga gcttgaagaa
    84361 agcaagaaat taacagaaaa agaaaaagct gagctacaag caaaacttga agcagaagca
    84421 aaagccctca aagaacaatt agcaaaacaa gctgaagaac ttgcaaaact aagagctgga
    84481 aaagcatcag actcacaaac ccctgatgca aaaccaggaa acaaagctgt tccaggtaaa
    84541 ggtcaagcac cacaagcagg tacaaaacct aaccaaaaca aagcaccaat gaaggaaact
    84601 aagagacagt taccatcaac aggtgaagca gctaacccat tcttcacagc ggcagccctt
    84661 actgttatgg caacagctgg agtagcagca gttgtaaaac gcaaagaaga aaactaagct
    84721 atcattttgt aatactgagt gaacatcaag agagaaccag tcggttctct cttttatgta
    84781 tagaagaatg aggttaagga gaggtcacaa actaaacaac tcttaaaaag ctgaccttta
    84841 ctaataattg tttttgtttt ataatg
//
LOCUS       DAUGUF010000003        72994 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUGUF010000003 DAUGUF010000000
VERSION     DAUGUF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72994
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.003"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            147..1430
                     /locus_tag="VIB71_000163"
     CDS             147..1430
                     /locus_tag="VIB71_000163"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEQ8821925.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLGLGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            1642..2217
                     /locus_tag="VIB71_000164"
     CDS             1642..2217
                     /locus_tag="VIB71_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEQ8821926.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            2474..4078
                     /locus_tag="VIB71_000165"
     CDS             2474..4078
                     /locus_tag="VIB71_000165"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEQ8821927.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            4246..5172
                     /locus_tag="VIB71_000166"
     CDS             4246..5172
                     /locus_tag="VIB71_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8821928.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            5226..5311
                     /locus_tag="VIB71_000167"
     tRNA            5226..5311
                     /locus_tag="VIB71_000167"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5260..5262,aa:Leu,seq:aag)
     gene            5518..6399
                     /locus_tag="VIB71_000168"
     CDS             5518..6399
                     /locus_tag="VIB71_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEQ8821929.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQTLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            6781..6969
                     /locus_tag="VIB71_000169"
     CDS             6781..6969
                     /locus_tag="VIB71_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEQ8821930.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            7121..7486
                     /locus_tag="VIB71_000170"
     CDS             7121..7486
                     /locus_tag="VIB71_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8821931.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            7486..9150
                     /locus_tag="VIB71_000171"
     CDS             7486..9150
                     /locus_tag="VIB71_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEQ8821932.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKTKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            9387..10277
                     /locus_tag="VIB71_000172"
     CDS             9387..10277
                     /locus_tag="VIB71_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEQ8821933.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            10506..11360
                     /locus_tag="VIB71_000173"
     CDS             10506..11360
                     /locus_tag="VIB71_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEQ8821934.1"
                     /translation="MKSKKVVSVISLTLSLFLVIGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            11553..12749
                     /locus_tag="VIB71_000174"
     CDS             11553..12749
                     /locus_tag="VIB71_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEQ8821935.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            13012..13563
                     /locus_tag="VIB71_000175"
     CDS             13012..13563
                     /locus_tag="VIB71_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8821936.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLFSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            13630..14001
                     /locus_tag="VIB71_000176"
     CDS             13630..14001
                     /locus_tag="VIB71_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8821937.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            14039..15385
                     /gene="glnA"
                     /locus_tag="VIB71_000177"
     CDS             14039..15385
                     /gene="glnA"
                     /locus_tag="VIB71_000177"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEQ8821938.1"
                     /translation="MAITVADIRREVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(15613..17295)
                     /locus_tag="VIB71_000178"
     CDS             complement(15613..17295)
                     /locus_tag="VIB71_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8821939.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEALIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(17297..17527)
                     /locus_tag="VIB71_000179"
     CDS             complement(17297..17527)
                     /locus_tag="VIB71_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEQ8821940.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            17810..18508
                     /gene="tsaB"
                     /locus_tag="VIB71_000180"
     CDS             17810..18508
                     /gene="tsaB"
                     /locus_tag="VIB71_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEQ8821941.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHAPLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            18480..18935
                     /gene="rimI"
                     /locus_tag="VIB71_000181"
     CDS             18480..18935
                     /gene="rimI"
                     /locus_tag="VIB71_000181"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEQ8821942.1"
                     /translation="MIVTTLSESNMKTVEEQAKKIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKLIGKRPDYYRNPIETALLMKREGKHDR"
     gene            18925..19953
                     /gene="tsaD"
                     /locus_tag="VIB71_000182"
     CDS             18925..19953
                     /gene="tsaD"
                     /locus_tag="VIB71_000182"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEQ8821943.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(20124..20393)
                     /gene="rpsN"
                     /locus_tag="VIB71_000183"
     CDS             complement(20124..20393)
                     /gene="rpsN"
                     /locus_tag="VIB71_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEQ8821944.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(20613..21371)
                     /locus_tag="VIB71_000184"
     CDS             complement(20613..21371)
                     /locus_tag="VIB71_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8821945.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSCQSDTH"
     gene            21611..22390
                     /gene="udp"
                     /locus_tag="VIB71_000185"
     CDS             21611..22390
                     /gene="udp"
                     /locus_tag="VIB71_000185"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEQ8821946.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            22411..23613
                     /locus_tag="VIB71_000186"
     CDS             22411..23613
                     /locus_tag="VIB71_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEQ8821947.1"
                     /translation="MQFIYSIIGILLILGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            23643..24314
                     /gene="deoC"
                     /locus_tag="VIB71_000187"
     CDS             23643..24314
                     /gene="deoC"
                     /locus_tag="VIB71_000187"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEQ8821948.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECEDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAETFIALGASRLGTSRIIKIVKNEAI
                     KTDSY"
     gene            complement(24409..25578)
                     /locus_tag="VIB71_000188"
     CDS             complement(24409..25578)
                     /locus_tag="VIB71_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8821949.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGKVLTSTEVVSVKKQDDLFYLKSADQTFSCHKLIV
                     TTGGKAYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            25783..26313
                     /locus_tag="VIB71_000189"
     CDS             25783..26313
                     /locus_tag="VIB71_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEQ8821950.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFFTRLFAK"
     gene            26362..26949
                     /locus_tag="VIB71_000190"
     CDS             26362..26949
                     /locus_tag="VIB71_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEQ8821951.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSNKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            27101..27838
                     /locus_tag="VIB71_000191"
     CDS             27101..27838
                     /locus_tag="VIB71_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ8821952.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
                     SNYLQKFWLVYVAMGIFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPR
                     TRKLTCSHCHQKSYCLELAKEDTVSRG"
     gene            complement(27895..28194)
                     /locus_tag="VIB71_000192"
     CDS             complement(27895..28194)
                     /locus_tag="VIB71_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEQ8821953.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(28387..28761)
                     /locus_tag="VIB71_000193"
     CDS             complement(28387..28761)
                     /locus_tag="VIB71_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8821954.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            28931..29152
                     /locus_tag="VIB71_000194"
     CDS             28931..29152
                     /locus_tag="VIB71_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8821955.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(29232..31514)
                     /locus_tag="VIB71_000195"
     CDS             complement(29232..31514)
                     /locus_tag="VIB71_000195"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEQ8821956.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDHYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRASKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(31536..32195)
                     /locus_tag="VIB71_000196"
     CDS             complement(31536..32195)
                     /locus_tag="VIB71_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8821957.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            32361..33557
                     /locus_tag="VIB71_000197"
     CDS             32361..33557
                     /locus_tag="VIB71_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8821958.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMVIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            34059..34907
                     /locus_tag="VIB71_000198"
     CDS             34059..34907
                     /locus_tag="VIB71_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ8821959.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSRKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(35243..36139)
                     /locus_tag="VIB71_000199"
     CDS             complement(35243..36139)
                     /locus_tag="VIB71_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEQ8821960.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            36437..37189
                     /locus_tag="VIB71_000200"
     CDS             36437..37189
                     /locus_tag="VIB71_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEQ8821961.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            37174..38124
                     /locus_tag="VIB71_000201"
     CDS             37174..38124
                     /locus_tag="VIB71_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEQ8821962.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADTTVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTSERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(38304..40631)
                     /gene="pflB"
                     /locus_tag="VIB71_000202"
     CDS             complement(38304..40631)
                     /gene="pflB"
                     /locus_tag="VIB71_000202"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEQ8821963.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            40840..41934
                     /gene="dinB"
                     /locus_tag="VIB71_000203"
     CDS             40840..41934
                     /gene="dinB"
                     /locus_tag="VIB71_000203"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEQ8821964.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNLALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGEQIRRI
                     FKRYTDVVEPMSIDEAYLDVTNNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(42027..42509)
                     /locus_tag="VIB71_000204"
     CDS             complement(42027..42509)
                     /locus_tag="VIB71_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821965.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGFFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIIFCTQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTLSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(42600..45053)
                     /locus_tag="VIB71_000205"
     CDS             complement(42600..45053)
                     /locus_tag="VIB71_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEQ8821966.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFR
                     AALLHCLLEESVSRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIASNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(45111..45704)
                     /gene="lepB"
                     /locus_tag="VIB71_000206"
     CDS             complement(45111..45704)
                     /gene="lepB"
                     /locus_tag="VIB71_000206"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8821967.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(45715..46617)
                     /locus_tag="VIB71_000207"
     CDS             complement(45715..46617)
                     /locus_tag="VIB71_000207"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEQ8821968.1"
                     /translation="MNTLVLKIDAILSKHLKKQLASYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            46774..47082
                     /locus_tag="VIB71_000208"
     CDS             46774..47082
                     /locus_tag="VIB71_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821969.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETVAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            47085..47630
                     /locus_tag="VIB71_000209"
     CDS             47085..47630
                     /locus_tag="VIB71_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEQ8821970.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            47779..50118
                     /locus_tag="VIB71_000210"
     CDS             47779..50118
                     /locus_tag="VIB71_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEQ8821971.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKITVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADRNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFTLVRVQEEQ
                     KVKSKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG"
     gene            50122..50622
                     /locus_tag="VIB71_000211"
     CDS             50122..50622
                     /locus_tag="VIB71_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8821972.1"
                     /translation="MESYEQFYAKLSQPFRKSPQLIILLNFLLKIVTGMMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDCPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            50703..51017
                     /gene="trxA"
                     /locus_tag="VIB71_000212"
     CDS             50703..51017
                     /gene="trxA"
                     /locus_tag="VIB71_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEQ8821973.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(51069..51656)
                     /locus_tag="VIB71_000213"
     CDS             complement(51069..51656)
                     /locus_tag="VIB71_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8821974.1"
                     /translation="MEIGQQIIRYRKQQALSQEKLAEKVYVSYQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSNGKLLDEIEKREE
                     RAKLPYQKPLIVTVFFLITVAFAFASRFMFTWLFH"
     gene            complement(51732..52856)
                     /gene="mutY"
                     /locus_tag="VIB71_000214"
     CDS             complement(51732..52856)
                     /gene="mutY"
                     /locus_tag="VIB71_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEQ8821975.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            53054..53347
                     /locus_tag="VIB71_000215"
     CDS             53054..53347
                     /locus_tag="VIB71_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8821976.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            53520..53810
                     /locus_tag="VIB71_000216"
     CDS             53520..53810
                     /locus_tag="VIB71_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEQ8821977.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            53832..54323
                     /locus_tag="VIB71_000217"
     CDS             53832..54323
                     /locus_tag="VIB71_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8821978.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            54488..54727
                     /locus_tag="VIB71_000218"
     CDS             54488..54727
                     /locus_tag="VIB71_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEQ8821979.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKITTAIKRARVMALMPYVNED"
     gene            complement(54860..55516)
                     /locus_tag="VIB71_000219"
     CDS             complement(54860..55516)
                     /locus_tag="VIB71_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEQ8821980.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(55648..56592)
                     /locus_tag="VIB71_000220"
     CDS             complement(55648..56592)
                     /locus_tag="VIB71_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEQ8821981.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            56795..59623
                     /gene="uvrA"
                     /locus_tag="VIB71_000221"
     CDS             56795..59623
                     /gene="uvrA"
                     /locus_tag="VIB71_000221"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEQ8821982.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
                     GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVIYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            59739..60812
                     /locus_tag="VIB71_000222"
     CDS             59739..60812
                     /locus_tag="VIB71_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8821983.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRFIKDTSEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKAIAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            60847..61308
                     /locus_tag="VIB71_000223"
     CDS             60847..61308
                     /locus_tag="VIB71_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEQ8821984.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            61404..61961
                     /gene="efp"
                     /locus_tag="VIB71_000224"
     CDS             61404..61961
                     /gene="efp"
                     /locus_tag="VIB71_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEQ8821985.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            62007..62396
                     /locus_tag="VIB71_000225"
     CDS             62007..62396
                     /locus_tag="VIB71_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8821986.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            62389..62841
                     /gene="nusB"
                     /locus_tag="VIB71_000226"
     CDS             62389..62841
                     /gene="nusB"
                     /locus_tag="VIB71_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEQ8821987.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(62982..63947)
                     /locus_tag="VIB71_000227"
     CDS             complement(62982..63947)
                     /locus_tag="VIB71_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8821988.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(63952..65391)
                     /locus_tag="VIB71_000228"
     CDS             complement(63952..65391)
                     /locus_tag="VIB71_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEQ8821989.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGHYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGV
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFTDQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVKGQAFGHYYEMRY"
     gene            65633..67516
                     /locus_tag="VIB71_000229"
     CDS             65633..67516
                     /locus_tag="VIB71_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8821990.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            67747..70734
                     /locus_tag="VIB71_000230"
     CDS             67747..70734
                     /locus_tag="VIB71_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8821991.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKAGQESQKVKEILAKAQQADKQAQELAKMKIPE
                     KIPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLF
                     WKELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDVEHDSIPKVNGEASDENLKRSIDVFEEIGKLIGPKGVDKSRLF
                     IMDSTYMADKNPLIERGASYINLLLVQVYGSQGEKGVFQNDTKLVTDTPEERWQGYSK
                     YIRPEQYMIGFSFYEENAQEGNLWYDINSRKDEDTANGINTDITGTRAERYARWQPKT
                     GGAKGGIFSYAIDRDGVAHQPKKYAKQKEFKDATDNIFHSDYSVSKALKTVMLKDKSY
                     DLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNKFKKLAQLD
                     LIGLSRITKLDQSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLKVSGLTGLK
                     ELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLSTVSNHVGS
                     NKQTVKFDKQKPTGHYPDTYGKTSLRLPVANEKVDLQSQLLFGTVTNQGTLINSEADY
                     KAYQNQQIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATDKEETYKVD
                     FFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADKEMSRNVFDGSLGGDRSN
                     LLGMSGPKSTIIFNLKESGIVKHWRFFNDRARSPQNPAEDIQEIKLQVFDSEKYDIET
                     LLKTPNQFDKDDYWITVDSYKSKSETVNNYDQVLKMNSAKYWRVTVDTKGGNYSWPSL
                     PELQILGYPLPNADTIMKTVTIAKGLSQQKDKFSQKMLDELKIKEMALETSLNSKIFD
                     VTAINANAGVLKDCIEKRQLLKK"
     gene            70998..71882
                     /locus_tag="VIB71_000231"
     CDS             70998..71882
                     /locus_tag="VIB71_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8821992.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIAQT
                     IAYFKTFEADLAGMAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            71977..72930
                     /gene="manA"
                     /locus_tag="VIB71_000232"
     CDS             71977..72930
                     /gene="manA"
                     /locus_tag="VIB71_000232"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEQ8821993.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
BASE COUNT        22549 a        12677 c        15358 g        22410 t
ORIGIN      
        1 tataaattga aaataactgt tagtagacta atgacaggta gatactctta atagcgcgtt
       61 tgatttcacg cataaaaagc tttaaaaacg ctttaaatta tgataaaatg aactgtatcg
      121 aaattatttt aaggagaaat gacttaatgt ctacatcatt tgaaaacaaa gctacaaatc
      181 gtggcgtgat tacatttaca attagtcaag ataaaataaa accagctctt gataaagctt
      241 ttaataaaat caaaaaagac ttaaatgcac caggtttccg taaaggacac atgcctcgtc
      301 cagtcttcaa ccaaaaattt ggtgaagaag ttctttatga agatgctttg aatattgtat
      361 tgccagaagc ttatgaagca gctgtgacgg aacttggtct tgatgtggtt gcacaaccaa
      421 aaatcgatgt tgtgtcaatg gaaaaaggga aagagtggac actttctgct gaagttgtga
      481 caaaacctga agtgaaactt ggtgattaca aaaaccttgt tgtagaagtt gatgcttcaa
      541 aagaagtttc agatgaagac gtggatgcta aaattgagcg cgaacgtcaa aaccttgcgg
      601 aactcattat taaagacggt gaagcagctc aaggtgacac tgttgtgatt gactttgttg
      661 gttcagttga tggtgttgag tttgatggcg gtaaaggaga taacttctct cttggacttg
      721 gttcaggaca atttatccca ggttttgaag atcaactagt tggtgctaaa gctggcgatg
      781 aagtagaagt taatgtcaca ttcccagaat cttaccaagc agaagatctt gcaggtaaag
      841 ccgctaaatt tatgacaact attcacgaag tcaaaacaaa agaagtacca gagcttgatg
      901 atgagcttgc aaaagatatt gatgaagatg ttgacacact tgaagactta aaagtaaaat
      961 atcgtaaaga acttgaagca gctcaagaaa ctgcttatga tgatgctgtt gaaggagctg
     1021 cgattgaatt agcagttgca aatgctgaaa ttgttgattt acccgaagaa atgattcatg
     1081 aagaagtcaa ccgttcagtg aatgaattta tgggcaacat gcaacgtcaa ggaatctcac
     1141 ctgaaatgta cttccaattg actggtacaa ctcaagaaga tttacataac caatattcag
     1201 ctgaagctga caaacgtgtt aaaacaaacc ttgttattga agcaattgct aaagcagaag
     1261 gttttgaagc aacagatagt gaaattgaac aagaaattaa tgaccttgca acagaatata
     1321 acatgccagc tgaccaagtt cgttctcttc tttcagcaga tatgttgaaa catgatattg
     1381 caatgaaaaa agcagttgaa gtgattacaa gcacagcaag cgttaagtaa tcttattaag
     1441 gaacaaaacg tacaagccgg attagaacgt ctttctagtc tggtttttct ttttctaaag
     1501 ataaggaatt agttaaacgt tattttaatg aattagcttt aaagatttgt caagaagaag
     1561 tgatatgagt tgataaaagt tttgacgaat tacttttttt agcgtaaaat ggtagagaat
     1621 gataaaataa ggagaactgc cttgaaatta gacgtatttg caggacaaga aaaaagcgag
     1681 ctttccatga ttgaagtggc gcgtgccatt ttggaagaac gcggtcgcga caatgagatg
     1741 tactttagcg atttagtcaa tgagattcaa aattacttag gaaaatctga tgcaggtatt
     1801 cgtcatgcat taccattttt ctatactgac ttaaatacgg atggctcatt tattcctcta
     1861 ggtgaaaaca aatggggact tcgttcgtgg tatgctattg atgaaattga tgaagaaatt
     1921 attactctag aagaagatga agatggcgca caaaaacgta agaaaaaacg cgttaatgct
     1981 ttcatggatg gagatgaaga cgctattgat tatagagatg atgatccaga agatgaagat
     2041 ttcacagaag aatcagctga ggttgaatat gatgaagaag atccagatga tgaaaaatca
     2101 gaagtggagt catatgattc agaattgaat gaaattatcc ctgaagatga ttttgaagaa
     2161 gttgatatca atgaagaaga cgaagaagat gaagaagatg aagaaccagt tctctaatgt
     2221 ctttagttca gaaataaaaa tgtgattatc atttgacaaa ttgtctatta tagtttatat
     2281 tattattcgg gcacctcttt atgaggtcag gcaaaagctc tctagttaat agggggctat
     2341 ttttgttttc tagaataatg ccagtttgcc tctatattta gaaaactaag gtgataccta
     2401 accaatgtgg aaccaactaa tagggaatta acaagaaagc aatgctttta ttcagcttat
     2461 ataaaggagt actatgacga aatacatttt tgtaactggt ggtgttgtat catcaattgg
     2521 caaaggaatt gttgcggcaa gtcttggccg attgttaaaa aatcgtggac ttaaggtgac
     2581 gattcaaaaa tttgatcctt atattaatat tgatccaggg acgatgagcc cctatcagca
     2641 tggagaagta tatgtgacag atgacggtgc tgaaaccgac ttggatttgg gtcactatga
     2701 acgttttatt gatatcaatc ttaataaata ttccaatgtt acaacaggta aaatttatag
     2761 tgaagtcctt cgtaaagaac gtaaaggtga gtaccttgga gcgactgttc aggtgattcc
     2821 tcatatcaca gatgccctta aagaaaaaat caaacgcgca gcttcaacaa cggactctga
     2881 tgtaattatt actgaggtcg gggggactgt tggcgatatt gaaagtttac cgttcttaga
     2941 agctcttcgt cagatgaaag ctgatgttgg ttctgaaaat gtgatgtata ttcacaccac
     3001 cttgttgcca tatttaaagg cagcgggtga aatgaaaact aagccaacgc aacattccgt
     3061 taaagaattg cgtggtttag ggattcaacc gaatatgttg gttattcgta cggaagagcc
     3121 agttgagcag gggattaaaa ataaattggc tcagttctgt gatgtgaatt cagaagctgt
     3181 tatcgagtca cgtgatgtag aacacttgta tcaaattcca ttgaacttgc aagcccaatc
     3241 aatggatcag attgtttgtg atcatttgaa attgaatgcg ccacaagctg atatgactga
     3301 gtggtcagct atggttgaca aggtgatgaa tttaagaaaa acaacaaaaa ttgccttggt
     3361 tggtaaatat gtggaattgc cagatgccta cttatctgtt gtggaagcct tgaaacattc
     3421 tggttatgcc aatgataccg caattgacct aaaatgggtc aatgctaacg atgtgacggt
     3481 ggataatgca gctgacttgt tgggagatgc ggatgggatt attgtaccag gtggttttgg
     3541 tcaacgtggt acagaaggca agatccaagc gattcgctat gcccgcgaga atgatgtgcc
     3601 aatgcttggt atctgtcttg gcatgcaact gacttgtgtt gaatttgctc gccatgtcct
     3661 caatatggaa ggtgcaaact cttttgaatt agagccaagt actaaatacc ccatcattga
     3721 tatcatgcgt gatcaaattg atattgaaga tatgggaggt acgcttcgtc tgggattgta
     3781 cccatgtaaa ttgaaaccag gttcaaaagc agcaatggct tacaataatc aagaggtggt
     3841 gcaacgtcgt catcgtcacc gttatgagtt caacaacaaa ttccgtccag aatttgaagc
     3901 agctggtttt gttttctcag gggtatcacc tgacaaccgc ttagttgaaa ttgtagaatt
     3961 gaaagagaaa aaattctttg tagcagctca ataccaccca gaattgcaaa gccgtccaaa
     4021 tcgtcctgag gagctataca ccgcttttgt tacagctgct attaaaaata gcaattagtg
     4081 gttttaaggg taagtttgtg gcattctact tggctggcag atactgataa agattactag
     4141 ctattagagg gatcttttct ataaaaatag cattagaaaa agaaaaacgt gatattttta
     4201 ggttagcact ttctttttca gtcatttttt tgtaaaatac ttggtatgaa aactattcga
     4261 atagcaaagt atttaggaat tctattcctt ttgataactc ttattagcgt aggtgctagt
     4321 ttttatttct ttcatgttgc acaaataaga gaagagaaat cgtttattaa taataagaaa
     4381 cggagtacaa ataatccatt atacccagct gaacagtctt ttgacgcttt accttacgaa
     4441 aaacgtcaac taacaaatcg tgggttaaaa caagtggggt ggtacttacc agctgctcaa
     4501 aaaacaaaaa agacagctat tgttgttcat ggttttacga atgacaaaga agatatgaag
     4561 ccatatgcca tgctttttca tgatttgggc tataatgtct taatgccaga caatgaggcc
     4621 catggggaaa gtgaagggaa cttgattggt tatggctgga atgaccgcct taatgtcatg
     4681 gcttggacag accaactgat taaggaaaac cctgaaagcc aaatcacact ctttggctta
     4741 tctatgggtg ctgcaacagt aatgatggca agtggtgagc gattgcctgc gcaagtcacc
     4801 tccctcatcg aagattgcgg ttataccagt gtttgggacg aattgaagtt tcaggccaag
     4861 gctatgtaca acttgcctgc ctttccttta ctctatgaag tctctgcctt atctaagatt
     4921 cgagcaggtt ttagttacgg agaagcgagc tcagtgaaac agctggctaa aaataaacgt
     4981 ccaactttat ttatccacgg tgataaggat gattttgttc ctacaaaaat ggtttatgac
     5041 aattataagg ccacgaaagg tcctaaggaa atcttgattg ttaaaggggc aaaacacgcc
     5101 aaatcctttg aaacaaaccc agaacaatac cagaaaaaaa ttgccgcttt tttgaaaaaa
     5161 gttgagaaat aagtattgac agttaaactc acagttgcta taataattta tgttactgat
     5221 gagtagcggg gatggcggaa ttggcagacg cgcaggacta aggatcctgt gaccgcttta
     5281 ggtcgtgtgg gttcaagtcc cactctccgc ataatgtaag aggtgaatca ttgattcgtc
     5341 tctttttttt ggttaaatga aggacaagaa ggcatagatt tactggagaa aacttttgat
     5401 aatctgcttt tggaaaacgc tttaagcttg tgaaagacta gaaatttatg gaaaattgtg
     5461 ctagaatgaa caatgtaaac ggggagttat cccgaaaaat aagaggaggc cttacaaatg
     5521 gcaatcgttt cagcagaaaa atttgtccaa gcagctcgtg aaaacggata tgctgttggt
     5581 ggatttaaca caaacaactt agagtggact caagcaatct tgcgtgcagc agaagctaaa
     5641 caagctccag ttcttatcca aacatcaatg ggtgcagcaa aatacatggg tggttataaa
     5701 gtatgtcaaa ctcttattac taaccttgtt gagtcaatgg gtatcactgt tcctgttgct
     5761 atccaccttg atcatggtca ctacgaagat gctcttgagt gtatcgaagt aggttacact
     5821 tcaatcatgt ttgacggttc acaccttcca gttgaagaaa accttgctaa aactgcagaa
     5881 gttgttaaaa ttgcacatgc taaaggcgtt tcagttgaag ctgaagttgg tacaatcggt
     5941 ggtgaagaag acggtatcat tggtaaaggt gagctcgctc caatcgaaga tgctaaagca
     6001 atggttgaaa ctggaattga cttcttggca gctggtatcg gtaacatcca cggtccatac
     6061 ccagaaaact gggaaggtct tgctcttgac cacttagaaa aattaacagc agctgtacca
     6121 ggtttcccaa tcgtattgca cggtggttct ggtattcctg acgatcaaat caaagaagca
     6181 atccgtcttg gtgttgctaa agttaacgtt aacactgaaa gtcaaatcgc tttctctaac
     6241 gcaactcgtg aatttgctcg taactacgaa gctaacgaag cagaatatga tggtaaaaaa
     6301 ttatttgacc cacgtaaatt cttggctcca ggtatgaaag ctgttcaagg tgctgttgaa
     6361 gaacgtatcg atgttttcgg atcagctaac aaagcataat ttagagtatt aaatactcta
     6421 aagccctctt gagggctttt ttagatacaa ttgacaccct aaaatggata ccagtttctg
     6481 tgaaacaatc tttgattgtg aacaaacaaa gcataattta gagtattaaa atctggaccc
     6541 tgctatctat ggtaagtctt tttgttattg ttaaagaggt taagcggaat gttaatatgt
     6601 tttagctaaa aaatgtagtg taaaatgagt acgtagacta ttgtaatagt aattccgtaa
     6661 aattgttgaa aaagaaaatg ggaaatacct tgtcaaatta agcaccctat gatagaatag
     6721 ataggtatgt ggtgctagca catccgtaaa catattctac gtaggaggaa acagatcaaa
     6781 atggctaaag tatgttattt tacaggacgt aaaaccgttt ctggaaacaa ccgttcacac
     6841 gcgatgaacc aaacaaaacg tacagttaaa ccaaaccttc aaaaagttac tatccttgtt
     6901 gatggtaaac ctaaaaaagt ttgggcttct gctcgtgcgc ttaaatctgg taaagtagaa
     6961 cgcatctaat agaaataagc cttagggctt tttttattag cttatttcta tccataagct
     7021 agtcagggta ataaacgcta tcgttaacta ttctatctct tttacattac ttctaaaata
     7081 tgataaaata ggatgataaa aactttttga ggtagtaact atgactgtaa aaattaatac
     7141 aaaagatggt ctaatcgagc tatccgacga tgtgattgca actgtcgtgg gaggatcagc
     7201 aacggaaatt tttggtgttg ttggaatggc cagcaaaagt gcaataaaag acaattttca
     7261 atcactactt cgcaaagaaa actacgctaa gggtgttgta gtaaaatcaa cagatctggg
     7321 tatttctgtt gatgtctaca ctgtgatgag ttatggtgtg aaaatcagtg aagtctctaa
     7381 aaatatccaa gaacgcgtga aatttaacct tgaaagtcag cttggtctca ctgctgatat
     7441 ggtcaatgtt tacgtgcaaa atattaaggt tgtaggagaa aattagtgtc aaatattaca
     7501 acaagcttat tccaagaaat ggtccaagcg gcagcgactc gccttggcaa acaagcagaa
     7561 tatgttaatt ccttaaatgt ttttcctgtt ccagatggtg atacaggaac aaacatgagt
     7621 atgactatgg acaatggtgc caaggaagtt gctgataaac ctgcgtcaac tgtgggagaa
     7681 gttggacaaa tgttatcaaa aggtcttttg atgggagcgc gtggaaattc tggagttatt
     7741 acttcacaac tttttcgtgg ttttggtcaa agtattaagg gaaaagatga gctgacaggt
     7801 aaagatttgg cacaagcctt tcaagtgggt gtagaagttg cctacaaagc agtgatgaaa
     7861 cctgttgaag ggacaatctt gacagtatct cgtggagcag caaccgctgc cttaaaaaaa
     7921 gcagatctta cagacgacgc cgtggaagtc atgcaagctg ctttagacgg tgccaaaggt
     7981 gcccttgcta agacacctga tttattacca gtccttaaag aagttggtgt ggttgattca
     8041 ggcggtcaag gtcttgtctt tatctatgaa ggtttcctat ctgctttgaa tggcgactat
     8101 gtgacttcag cagactttaa agcgactcct gctaacatgt ctgaaatgat taatgctgag
     8161 catcacaaat ccgttgttgg tcatgtggct actgaagaca ttacctacgg ttattgtact
     8221 gaaatcatgg ttgcccttaa acaaggccca acctatgtga aagaattcaa ctatgatgag
     8281 tttcaaggct accttagtgg ccttggtgac tcgctgttag tggtcaatga tgatgagatt
     8341 gttaaagttc acgtccatac tgaagacccc ggacttgtga tgcaagaagg tcttaaatat
     8401 ggttcgctca tcaagattaa agtggacaat atgcgtaacc agcatgaagc acaggttcaa
     8461 aagactgatg tcgaaaaaac caaggctgaa gtaaaagact ttggcttgat tgcagtagta
     8521 gctggagaag gtttatctga aattttcaag gcgcaaggtg ttgattacgt gatttctggt
     8581 ggtcaaacca tgaatccatc tacagaagat attgttaaag ctattgaagc agttaatgcc
     8641 aaacaagtca ttatcttgcc aaacaataaa aatatcttta tggctgccca atctgctgca
     8701 gaagtggtgg atatcccggc tgctgttgtt gcaacacgta ctgttccgca aggatttacc
     8761 agcttgttgg cctttgatcc ttcaaaatct ttagaggaca atgtagcaga tatgtcaact
     8821 agtctttctg acgtggtcag tggaagcgtt actttggcag tccgtgacac caccattgat
     8881 ggtttagaaa tccatgaaaa tgatttcttg ggaatggttg atggtaaaat catcgtttca
     8941 aacccagaca tggaagcaac tctaaaagct gcctttgaaa agatgattga cgaagatagc
     9001 gagattgtga ctatctttgt tggtgaagaa ggtgatcaag acttagcaga agaacttgct
     9061 gggtatttag gagagactta cgaagatgtg gaagttgaga tccatcaagg agatcagcct
     9121 gtttacccat atctcatgag tgtagaataa tagaatacaa taaaaaaaga ggagttaggc
     9181 aaaggtctga ctctttttgt ctatattgat gtcgtaatga gtggttttag tgatggtaag
     9241 cccctaaaaa atgagggtaa tccatcacaa agctaatggt tacgatttaa tttgacaaaa
     9301 cctagaaaaa cattataatt gtattataac aataagtcaa gaactgaaaa cggttcagtt
     9361 ctaagatatg acaaggagga gattttatgt taggaccatt tatctttatt gcttttgggg
     9421 ttattgtaat cctagctatt gttgccagta ccctttatgt tgttcgtcaa caatctgttg
     9481 ccatcgtgga acgttttggt aggtaccaaa aaacagccac gagtggtatt catgtccgcc
     9541 ttccgtttgg gattgacaaa attgctgcgc gtgtgcagct gcgtctttta cagtcagaaa
     9601 tcatcgttga aaccaaaacc aaggacaatg tgtttgtaac tttgaatgtt gccactcagt
     9661 atcgtgttaa cgaacaaaat gtaacagatg cttactacaa attaatgaaa cctgaatctc
     9721 aaatcaagtc ttatattgaa gatgccttgc ggtcatccgt gccgaagttg accttagacg
     9781 aattgtttga gaaaaaagat gaaattgcct tggaagtaca acatcaagtg gcagaagaaa
     9841 tgtcaaccta tggatatatt attgtcaaaa ccttgattac caaggtggag cctgatgctg
     9901 aagtcaaaca gtcaatgaat gaaatcaatg cggctcaacg caaacgtgta gctgctcaag
     9961 agttggcaaa cgcagataaa attaaaattg tgacagcagc agaagcagag gctgaaaaag
    10021 atcgattgca cggggtaggg attgcccaac agcgtaaggc cattgtggat ggtttggcgg
    10081 agtctattca agagcttaaa gaagcgaata tttccttaaa cgaagaacaa atcatgtcca
    10141 ttttgttgac caaccaatac ctggataccc tcaatacctt tgcggcaaaa ggaaaccaaa
    10201 ccctttttct accaaataca ccaagtgggg tagaggatat ccgtacacaa gttttatctg
    10261 cccttaaaac aaaataacgt gtaaaagctt ggctaaaaag ttgctcaata ctggatttag
    10321 cagaaggcta tcataccttg tgaagtggca aacgacgaaa tgaatacatt acttttattg
    10381 gagaaatgaa agtaaaaaag cctttttcat gattaacaac atagtattga ttaaatgtta
    10441 agttgtattg acttttaaat taaataagtt taaaatcaac ttaataagca aaaaggagat
    10501 tttcaatgaa atccaaaaaa gttgttagtg ttatatcact taccttatcc ctttttttgg
    10561 tgataggttg tgctaaagtt gataacaaca aatcagttaa tcgtaagcct gctactaaac
    10621 aaacctataa tagctatagt gatgaccaat taagatcgcg tgaaaatacc atgtctgttt
    10681 tatggtacca gcgagctgcg gaaactcaag cgctttattt acaggggtat cagttagcaa
    10741 cggatcgctt aaaagaacaa ctcaataaac caacggataa accttattca attgtattag
    10801 atattgacga aacagttctt gataatagcc cttatcaagc taaaaatgtt ttggaaggaa
    10861 caggatttac acctgaaagc tgggattatt gggtacaaaa gaaagaagca aaaccggttg
    10921 ctggtgctaa agactttttg caatttgcag accaaaatgg tgttcaaatt tactacattt
    10981 cagacagatc aactactcaa gtagatgcta caatggaaaa tctccaaaaa gaaggtattc
    11041 cagtacaagg tcgtgatcat cttctattct tagaaaaagg cgtaaaatca aaggagagtc
    11101 gtcgtcaaaa ggtcaaagaa acaactaatg taacgatgct atttggtgat aatcttctag
    11161 attttgctga tttttcaaaa aaatctcaag aagatagaac agctttatta tcagatttgc
    11221 aagaagagtt tggaagacgc tttatcattt tccctaatcc tatgtatggt tcatgggaag
    11281 gtgccattta taaaggtgaa aagctggatg tgcttaagca actagaggaa cgccgtaaaa
    11341 gtttaaaaag ctttaaataa agtaattgaa aaagaggtgc aaaagaaaat gtaacctctt
    11401 tttaagtact attattttct gaaaataggg ttaatgactg aaaaaaatgt tgattttgtg
    11461 aaatgattat tttattattt tcatatttta tctttatgct aggaattgtg gtataatgga
    11521 ggagtataaa aaatattaag gagtctattc acatggctaa attgactgtt aaagacgttg
    11581 atttgaaagg taaaaaagtc ctcgttcgtg ttgactttaa tgtgcctttg aaagatggcg
    11641 ttatcactaa cgacaaccgt atcactgcgg ctcttccaac aatcaagtat atcatcgaac
    11701 aaggtggtcg tgctatcctc ttctctcacc ttggacgtgt taaagaagaa gctgacaaag
    11761 aaggaaaatc acttgcaccg gtagctgctg atttagctgc taaacttggt caagatgttg
    11821 tattcccagg tgttactcgt ggttcaaaat tagaagaagc aatcaatgct ttggaagatg
    11881 gacaagttct tttggttgaa aacactcgtt ttgaagatgt tgacggtaag aaagaatcta
    11941 agaatgacga agaacttggt aaatactggg cttcacttgg agatggaatc ttcgttaacg
    12001 atgcatttgg tacagcacac cgtgctcacg catcaaacgt aggtatttca gcaaacgttg
    12061 aaaaagctgt agctggtttc cttcttgaaa acgaaattgc ttacatccaa gaagcagttg
    12121 aaactccaga acgtccattc gtagctattc ttggtggctc aaaagtttct gataagattg
    12181 gtgttatcga aaatcttctt gaaaaagctg ataaagttct tatcggtggt ggtatgactt
    12241 acacattcta caaagctcaa ggtatcgaaa tcggtaactc acttgtagaa gaagacaaat
    12301 tggatgttgc taaagacctc cttgaaaaat caaatggtaa attgatcttg ccagttgact
    12361 cgaaagaagc aaacgcattt gctggttaca ctgaagttcg cgacactgaa ggtgaagcag
    12421 tttcagaagg cttccttggt cttgacatcg gtcctaaatc aatcgctgag tttgaccaag
    12481 cacttactgg tgctaaaaca gttgtttgga acggacctat gggtgtcttt gaaaaccctg
    12541 acttccaagc tggtacaatc ggtgtcatgg acgctatcgt taaacaacca ggcgttaaat
    12601 caatcatcgg tggtggtgat tcagcagcag ctgctatcaa ccttggccgt gctgacaaat
    12661 tctcatggat cagtaccggc ggaggcgcta gcatggaact tctcgagggt aaagtattac
    12721 caggtttggc agcattgact gaaaaataat agtcattata atatatagta aagggcatgc
    12781 tgatgcatgt ctttttttag ttgatcatgt acagttattg aactttccct aacttcactt
    12841 atcatttact agtttttaga tatagtggta tttggctgac actgcaattt tcaaaagttt
    12901 atgacgattt catatcaatt ggtttataaa agatatccta atcataaata aaacgtttac
    12961 caaaagggtt ttatggattg atatgttaaa atagatagtg aagggatagg tatgaaaacg
    13021 ttaagaaaat tattatctaa ttacaagttt gatattaaaa agtttaaatt gggaatgaga
    13081 acattgaaaa caggcttatc ggtcttttta gttttattgg tttttcattt atttggttgg
    13141 aaagggcttc aaattggtgc tctaactgct gtatttagtt taagagaaga ctttgataaa
    13201 agcgtgcact ttggcttttc tagaattatt ggtaatagta taggtggcct attctcctta
    13261 gtattttttg cattcaatga gatatttcat caagcttttt gggttacttt attaattgtt
    13321 cctatttgta ccatgttatg tatcatggtt aatgttgcat gtaataataa atcaggtatt
    13381 attggggcag tggctgctct tttgattatt acactgtcta ttccaacagg acaaacgttt
    13441 atttatgtga cttcgcgggt atttgaaaca ttttgtggcg tctttgtagc tattttagtt
    13501 aatactgatg ttgaacttat taaaaataaa tggtttaaca aaaaacacag tgatgttaga
    13561 taatataaca tatatacttg acaggttatt tttttcagcc tataataagg aagatgaaag
    13621 gagtttgtca tgaaagaaaa agaacttaga cgctcaatgg ctgtttttcc tattggaacg
    13681 gtgatgacat taacagatct ctctgcgaga caaattcgct attatgaaga tcaaggttta
    13741 attaagcctg aacgaacgca agggaatcgg cgtatgtttt ccttaaatga catggaccga
    13801 cttttggaaa ttaaagattt tttgtctgag ggattaaata ttgcagctat taaacgcgaa
    13861 tatgtcgagc gtcaaggtaa gttaatgcaa aaacaaaaag ctctaacaga tgcagatgtc
    13921 agacggatct tacatgatga aatgctgaca caaagcggtt tttctactcc ctcacagcat
    13981 attggtaatt ttcgtattta agatatgaat tgtataaaat ttaaaggaga cctatttaat
    14041 ggcaataaca gtagctgaca ttcgtcgtga agtcaaagaa aaaaatgtaa cgtttcttcg
    14101 cttgatgttc actgatatca tgggcgttat gaaaaatgtg gagattcctg caactaaaga
    14161 acagttagac aaagtattgt ctaacaaggt tatgtttgat ggttcatcta tcgaaggttt
    14221 tgtacggatc aatgagtcag atatgtacct ttaccctgat ttagacactt ggattgtttt
    14281 tccctgggga gatgaaaatg gagcagttgc aggtttaatt tgtgatattt atacagcaga
    14341 aggaaagcct tttgcaggag atcctagagg aaatttaaaa agagccctga aacacatgaa
    14401 cgagatcggc tacaaatcat ttaatcttgg accagaacca gaatttttcc tttttaagat
    14461 ggatgataaa ggtaatccga cacttgaagt taacgataat ggtggttatt ttgatttagc
    14521 gccaattgac ttagcagaca acacgcgccg tgaaattgtg aatattttaa cgaaaatggg
    14581 ttttgaagtg gaagctagtc atcatgaagt ggctgttggt caacatgaga ttgattttaa
    14641 atatgcagat gttttgaaag cttgtgataa tattcaaatt tttaagctag ttgtaaaaac
    14701 gattgcccgt gaacatggac tttatgctac tttcatggct aaaccaaaat ttggaatagc
    14761 tggatcaggg atgcactgta acatgtcttt gtttgataac caaggtaata atgcttttta
    14821 tgatgaaact gataagcgag ggatgcagct atcagaagat gcttattatt tcttgggagg
    14881 actaatgaag catgcttata actacactgc tatcactaac cctacagtga attcttacaa
    14941 acgattagtt ccgggttatg aggcacctgt ttatgtcgct tgggctggaa gtaatcgttc
    15001 accgcttatc cgtgttccag catcacgtgg tatgggaacg cgtttggagt tacgttcggt
    15061 tgatccgaca gctaatcctt atttagcctt ggctgttctc ttggaagctg gattagatgg
    15121 tatcattaac aaaattgaag ctccagaacc cgttgaagct aatatttata ccatgacaat
    15181 ggaagaacga aatgaagcag gcattattga tttgccatca acgcttcata atgccttaaa
    15241 agctcttcaa aaagatgatg tggtacaaaa ggcactagga taccatatct acactaattt
    15301 cttagaagca aaacgaattg aatggtcttc ctatgcaact tttgtttctc aatgggaaat
    15361 tgaccattat attcataact attagagtta tcaggacctg ctcaagttga gtgggtcttt
    15421 tggatgagct attgtatttg agctagcaag ctattattag ctgatcggac accaattgat
    15481 tttccattat agaaaactaa aaaccagtcc atgttctatg aggactggtt tttagtttga
    15541 taattatctg aactagaact gatatgttaa agatatagac agatagtatt aagaaatgag
    15601 tcttatttga ttttagtgct tatcaggtgt taagaccatc ggaattataa ttggttcacg
    15661 ctcagtcttt tcatacaaga atggacgaag agcattgacg atagcaccgt taactgattg
    15721 gatgctagca tccttatttt ttaaagcaat acggatagcg ttaaagagca cacgttggct
    15781 ttcgcggatc aagtcacctg actcacgcat ataaatgaaa ccacggctca gaatatctgg
    15841 tccagctaaa atcatttgtg tgttaaaatc aacagttgca acagctaaga caacaccatc
    15901 ttctgacaaa tcacggcggt ctcgtaaaac ggctgctcca atatccccga tgccattacc
    15961 atccacgtag atgtcttggg cattaaagtg accagcaata cgcgcactgt cactggttaa
    16021 agctagaacg tctccatttt ccataataaa gatattttct tttggaatac caatatccat
    16081 cgccagtcct gcatgaactt tttgcatgcg atactcacca tgtactggca tgaaatattt
    16141 tggtttaatc aaactaagca tgagcttttg ttcttgctgt cctccatgac cagaagtatg
    16201 aatattattg acttttccat gaataacatc aacaccagct tcttggatgg tattgattaa
    16261 tttattgaca cttgtggtat taccagggat tggacttgat gagaaaatca cagtatcacc
    16321 aggctgtaaa gttacttgac gatgagtgcc attagcgata cgagcaagtg ctgccataga
    16381 ctcaccttga ctacctgtac acataattaa agcttcacta gcatgaagat ttttaagttc
    16441 gcttggctca atgaaggtac cttttggaac tttaatatag ccaagttcaa taccgttaac
    16501 aattgctttt tccatagaac gaccaaaaac ggcaatttta cgtcccgttt taacagcagc
    16561 ttctgcagcc tgttgcaaac ggtagatgtt tgaagcgaag gaagcaaaaa taatacgccc
    16621 atgaatacct tcgataattt ttaaaatgga ttggccaaca actttttcag agttagtaaa
    16681 ggttgggatt tcagcattag ttgagtctga taataagcaa aggacacctt cttcaccaag
    16741 cgctgccata cgttgtaaat ctgcaggatc tcctactggc gtgaagtcaa atttaaaatc
    16801 accagtacag ataatcttac cttgaggggt gtgaataaca ataccgaccg gttctggaat
    16861 ggaatgagta gtcttgaaga aagtgacgct catgttttta aaagttaact cggtgttgtg
    16921 attgatttcg taaacagttg cttcacgcca aagaccatgt tcttccaatt taccacggat
    16981 aagagcaagt gctaaaggtc ctgcgtagat agggatatta gcctgtttga gaagaaatgg
    17041 aataccacca atgtggtctt cgtgaccatg tgtaataaca agagctttga cccggtctaa
    17101 gttatcgaca atgtaagaat agtctggaat aacgtaatca attcccaaaa gatcatcttc
    17161 tgggaatttg ataccggcat caacgataat gatctcgtct tgatactcaa taccataagt
    17221 attcttccca atctctccca gaccaccaat ggcaaacacc ccaacttcat taggttttaa
    17281 actgatattt gtcatcttag aactccgtta attcaaaaac accggtctct ttttcgtaat
    17341 cgaggtgttt gtcagaaagt agctcgataa attccacgtt ataataggtg ttatcttcaa
    17401 cgagacgacg agccttgata cggccatcga gttcatcagt agcatcaata ttaagataga
    17461 gtgctttagt actttcacga cgtgggcttt gatcctttgt ttcttgatag aaaactttat
    17521 aaatcatttg ttttttttcc tttcgttatg aatcaattat ccaaacaata ataaataggt
    17581 caaaaggtag gtgttccatt ttgacggttt tatatgttgt cattattgtg tagtagatta
    17641 attcctgatt ctgtgcaatt attacaatta taccataaac ttagctttta gtaaaaaatt
    17701 taggtacatt tatggtatag tctaaatcaa attaagagtc agcctttttg tttatgattc
    17761 ttaatttgtg ttataattga tactagaact tgcagtagaa aggcataaaa tgaagacact
    17821 tgcatttgat acctcaaata aaaccttgtc ccttgctata cttgatgatg agacacttct
    17881 agcagatatg acccttaaca ttcagaaaaa tcatagtgtt agccttatgc ctgctattga
    17941 ttttttgatg acttgtactg atcttaaacc tcaagattta gaaagaatag tggttgcaaa
    18001 aggccctgga tcttacacag gtttacgagt ggcagttgct actgcaaaaa cgttagcgta
    18061 cagtttaaat attgcattgg tcgggatttc gagtctatat gctttggctg cgtctacttg
    18121 taaacagtat ccaaatactt tggtggtgcc attgattgat gctagaaggc aaaatgcgta
    18181 tgtaggttat tatcggcaag gaaaatcagt gatgccacaa gcccatgctc cactagaagt
    18241 tattatagaa caattagtag aagaagggca gctgattttt gttggggaga ctgctccttt
    18301 tgctgagcaa attcaaaaga aactacctca ggcgatacta cttccaaccc tgccttctgc
    18361 ttacgaatgt ggtcttttgg ggcaaagttt ggcaccagaa aatgtagacg cctttgtccc
    18421 tcaatatctc aagagagtgg aagctgaaga aaactggctc aaagataatg agataaaaga
    18481 tgatagtcac tacgttaagc gaatctaata tgaaaacagt tgaagaacaa gcaaaaaaaa
    18541 tttatcagct tttggaaatg gtttatggca cgtctccttg gactttagaa caagtattaa
    18601 tcgatatacg gcgggatcaa acagattatt tcctactata tgatcatgat aaattgctag
    18661 gttttttagc tattcaagat ttagctggtg aagttgaaat gactcaaatt gctatactac
    18721 ctagtcatca aggacttggg ctagcgtctc aattgatgac gcatttagat agcattgaaa
    18781 gtgacatttt tttagaggtt agagaatcta atcatagagc acagggttta tatcagaagt
    18841 ttggttttaa acttattggc aaaagaccag actactatag aaatcctata gaaacagctt
    18901 tattgatgaa acgggaagga aaacatgaca gataggtata ttttagcagt tgagagttct
    18961 tgtgatgaga ccagtgtagc gattttaaaa aacgaaagta ccctcttaag taatgtcatt
    19021 gcaagtcagg ttgagagcca caaacgtttt ggtggtgtgg tgccagaagt agctagtaga
    19081 caccatgtcg aagtgattac gacttgcttt gaggatgctt tgcaagaagc tggcatcagt
    19141 gcttcagatt tatcagcagt tgcggtaact tatggccctg gacttgttgg agccttgtta
    19201 gttggattag cagctgcgaa ggcttttgct tgggcaaatc atttaccttt gattccggtt
    19261 aatcatatgg caggtcactt aatggcagcg cgtgaacaaa agcctttagt ttatccttta
    19321 atagcactgt tggtttcagg aggacacaca gaattggttt atgtcccaga gccaggggat
    19381 tatcatatta ttggcgagac gcgtgacgac gctgttggtg aggcttatga taaagttggg
    19441 cgtgtgatgg gcttaaccta tccggcagga cgtgaaattg accagttggc tcataaaggt
    19501 caagatactt atcatttccc tcgtgctatg ataacagaag accacttaga attttctttt
    19561 tcaggactca agtccgcttt tatcaatctt catcataatg ctaagcaaaa aggcgatgaa
    19621 ctgattctag aagatttgtg tgcatctttt caagcagctg ttctagatat tttattggcc
    19681 aaaacaaaaa aagctctgag cagataccct gcaaagatgc ttgtagtggc tggtggtgta
    19741 gcggcaaatc aaggattacg agatagatta gcacaagaaa ttacacatat agaagttgtg
    19801 attcctaaac taagactttg tggagataac gcgggtatga ttgctttagc agcagctatt
    19861 gagtatgaca aacagcattt tgctaatatg agcctaaacg cgaagcctag tttagctttt
    19921 gaccagtttc cagacagttt tgtaataaac tagtcacact tgctagttag taagatttat
    19981 aatggataag aatctccctt tgaaaaaaca acccggtatc ttggcatacc gggttgtcat
    20041 gatgataagt aattggcttc tatggttact aataattcag ataattacct gcaaaataat
    20101 tgtctgccta aggtgaagta agcttaccag ctagctttag tgacgccagg aagctgtcct
    20161 ttgtgagcta agtcacggaa attgatacgg ctaacaccaa acttacgcat gtaagcatga
    20221 ggacggccgt caattttgtc gcggttcttc aagcggtttg gatttgaatc acgaggcaat
    20281 ttgcgcagtg attcataatc gcccttcgct tttaagtcac gacgaaggtc agcgtactgt
    20341 tcaatcagtt ggagctgctt ttggtattta gcaatttttg acttttttgc cattgctttc
    20401 tccttcttaa tatttaataa cctcagagtc gttatcagcg ccctgaatcc acttaactgg
    20461 tatttaactg gttaagtgga tatataatca ttatacaata aataaaagca aaagcaacta
    20521 aaaaaattaa ctagttatct tttttagcca taatatcaaa aaactccaca tctaagtgtg
    20581 ggagtcaggt attaataact gtttaaaggt gtttaatgag tgtcgctttg gcaactttga
    20641 gattgaactt ttaagtcaaa taaatcagca ggaacgtagt gtttggttga gaccaagatg
    20701 tctttaccat tgtagagagt ttcttggatt aaaataaaag cactattttc tgatagagta
    20761 tacttagttg ctgtgtaatt gccagtcttg gtatagccga tttggttgca ggaatgagaa
    20821 gctttaccag attcatagat tttctcttct aagaaagtaa gaaggggctc ttcttgattg
    20881 agatttatag catatttaga aataacctca atagggataa aagataaact ataagcaata
    20941 gctttatttt ggctatgata ccagcgatca acaataatca caacaggagt ttcttgtttt
    21001 agggatgctg taatggcaac agtgggcact tcaatccgat attccaattc aacctttgtg
    21061 atgtcagatg ataggcttgc atatatgggg tgttgaagat attcgaaacc ttggtgatat
    21121 ttagtttcag gagtcttgag tataaaattt ccctttcctc tgatattttt tatgagatga
    21181 tcctcttgga ggagggctag ggatttacgt agtgtcatcc gactgacatt gagctgtcta
    21241 gcaagttcag gttctgatgg cagttgcatg ccaggactat atgtaccatc ttgaataagt
    21301 tgaaaaatag tattatatac ttgtacatgt ttaagttttt tgagtttttt ggttaagtcg
    21361 ttagtagaca tatcacttac ctcattaata atctttagtg gagtttaact tgtctaaaaa
    21421 ctattttagc actaacagta ttccttgatt agaattgtac ccatctatag tgttagtatc
    21481 tcacactcag gtactttttg tcaaaaaaga gatgaaaaac accttaaaaa agcgtttaca
    21541 aaatagggtg tgtgtgatac tatacaagtg tatcaaaaat tagacaagta aaatacagga
    21601 ggtttttaac atgcaaaatt attcaggtga agtcggattg caatatcacc tacagattcg
    21661 tccaggtgat gtaggtcgct atgttatcat gccaggtgat ccaaaacgtt gtgcaaaaat
    21721 tgcagaacat tttgataatg cagttcttgt agcagacagc cgtgaatatg ttacgtatac
    21781 aggtacatta aacggtgaaa aagtcagtgt tacttcaact ggtattggtg gtccatcagc
    21841 gtctattgcg atggaagaat tgaaactctg tggcgctgat acctttatcc gtgttggaac
    21901 atgtggtggt attgaccttg atgttaaagg cggagacatc gttattgcaa ctggagctat
    21961 ccgtatggaa ggtaccagta aagaatatgc tccgattgaa tttcctgctg tagctgactt
    22021 ggaagtgaca aatgctctag ttaatgcagc taaaaagctt ggttatacaa gtcacgcagg
    22081 agtagttcaa tgtaaagatg cattttacgg gcaacatgag ccagaacgta tgccagttag
    22141 ttatgaatta ttaaataaat gggaagcatg gaaacgtctg ggaacaaaag cgtctgaaat
    22201 ggaatctgca gctctttttg tagcagcaag tcatctagga gttcgttgtg gatcagattt
    22261 ccttgttgtt ggtaatcaag aacgcaacgc tttgggtatg gataacccaa tggctcatga
    22321 tacagaagca gctattcaag ttgctgttga agcactccgc acacttattg aaaatgataa
    22381 atcacaataa gcgaggtttt ggaagtcatc atgcaattta tttatagtat tattggtatt
    22441 ttattgatat taggaattgt gtatgcaatt tctttcaatc gtaagagtgt ttctctaagt
    22501 ttaattggaa aagctcttat cgttcaattc attattgcgc taatcttagt acgtatccca
    22561 ctaggccaac aaattgttag tgttgtttca actggagtta ctagcgtaat caactgtggt
    22621 caagctggtt taaattttgt gtttgggtca ttagcagata gtggcgcaaa aactggtttt
    22681 attttcgcta ttcaaacgct tggtaatatt gttttcttat ctgccctagt tagtctactt
    22741 tattatgtgg gaatccttgg atttgtagta aaatggatag gtaagggcgt tggtaaaatt
    22801 atgaaatcct cagaggttga gagttttgtt gccgtagcta atatgtttct tggtcaaaca
    22861 gacagtccaa ttttggttag caaataccta ggtcgtatga ctgatagtga gataatggtt
    22921 gtgttggtat caggtatggg aagtatgtca gtttctattc ttggtggcta tattgcatta
    22981 ggcattccaa tggaatatct cttgattgct tcaacaatgg ttcctattgg cagtattctc
    23041 attgctaaaa tcttattgcc tcaaacagaa cctgttcaaa aaattgatga cattaagatg
    23101 gataataaag gtaataacgc caatgtgatt gatgcaatcg ctgagggtgc aagcacaggt
    23161 gcacaaatgg ctttctcaat tggggctagt ttgattgcct ttgttggttt agtttctttg
    23221 attaatatga tgttaagtgg attgggaatc cgcttagaac aaatcttttc atatgttttt
    23281 gctccatttg gttttcttat gggatttgac cacaaaaaca ttcttctaga aggaaacctt
    23341 cttggaagta agttgatttt aaatgagttt gtttcgttcc aacaattggg tcacctaatc
    23401 aaatctttag attatcgtac agcattggta gcaactattt cactctgtgg ttttgctaat
    23461 ttatcaagtt taggtatttg tgtttcaggt attgctgttc tttgcccgga gaaacgtagc
    23521 accctagctc gacttgtttt ccgtgcaatg attggtggta ttgctgtaag tatgcttagc
    23581 gcctttatcg tcggtattgt aactctattc taaacgttga caaaagaaag aaggatagta
    23641 acgtggaagt aaaagatatt ttaaaaacgg tagaccatac tttgctagca acaacagcaa
    23701 cgtggccaga aatccaaaca attttagatg atgccatggc ttatgaaaca gcttcagcat
    23761 gtattccagc ttcttacgtc aaaaaagcag cagaatacgt ttcaggtaaa ttagctattt
    23821 gtactgttat tgggttccca aatggctata gtacaactgc agcgaaggtt tttgaatgtg
    23881 aagatgctat tcaaaatggt gctgatgaaa ttgacatggt cattaatttg acagacgtta
    23941 aaaatgggga ttttgatact gttgaagaag aaattcgtca aatcaaagct aaatgtcaag
    24001 accatatctt aaaagttatc gttgagacat gtcaattaac taaagaagaa cttatcgaac
    24061 tttgtggagt tgtcacacgt tcaggtgcag actttattaa aacctctact ggtttttcga
    24121 cagcaggtgc tacatttgaa gatgttgaag tgatggcaaa atatgtcggc gaaggtgtta
    24181 aaattaaggc agcaggtgga atctcatcat tggaagatgc tgaaacattt attgctttag
    24241 gagcttcacg cttgggtact agccgtatca tcaagattgt taagaacgaa gctataaaaa
    24301 ccgatagcta ttaacttaat cataccgatt tagcttgaga ctaaaacaaa aaactcatgt
    24361 aataggagtt aaaaagccta ctatcttagt gataataggc ttttttagct atgaagactt
    24421 ccctgcgatc catcctgaac aaagagctga ggtaatatta aaccctccgg tgtgagcatt
    24481 aatatctaag acttccccag caaaatacag cccaggaact ttcttacttt ccaaggtttt
    24541 aggattaatt tcttttaaat ccacgcctcc tttggtcaca aaagatttag ccaaagacat
    24601 ttttcctgta atgggtatct ggaggtgttt gagtttatca agcaattcct tctcttgttt
    24661 tggagagagt tgtttgacct tttcgggata atcttctgat aaaaaatcag ctactcgttc
    24721 aggcagtagg cctttaagag catttttgat gtttttatca cgttgatcac tcagataagc
    24781 ggttaagtca tctgttgata agtgtggcaa aaaatctagc tctgctattt ccccaccttt
    24841 cacaaaagaa gacaaacgga gagctgcagg acctgaaagg ccaaagtgag tgaagagtaa
    24901 gtcgtgtgtg atgacgtgtt tgtcataact aagagtaacg tcgtctaggg aaataccttg
    24961 caagactttg tgaggaaaat cagttaacag aggactctca gcagcttcta aatcagtcac
    25021 ggtcagttta aaatgccgtg caatatcatg tccaaaacct gttgaacccg ttgaaggata
    25081 ggccttgcct cctgtggtca caatcaattt atgacagcta aaagtctggt ctgcagattt
    25141 gaggtagaag aggtcatctt gttttttaac ggaaaccact tcagtgctgg ttagtacctt
    25201 gcctccaaga gccttgattt ttttctccag agcatcaatg attgtcctag atttatctgt
    25261 tgtggggaac atccgtccat ggtcttcttc tttgagtttg acgccgtttt cctcgaaaaa
    25321 ggcaatgatg tcatggttgt caaactggga aaaaacacta tataaaaagc ggccatttcc
    25381 aggaatgcct gccataaggt catcaaggtt accactatta gtgacattac agcgtccacc
    25441 accggttccc gctaattttt tacctaagcg gcgatttttt tcaattaaga gagttttata
    25501 gccatagtag ctgctggaga tggcggccat catgccagca gggccacctc caataataat
    25561 cgtatcgtat tgagtcatag ccttatttta tcataaaagc ggggggttta atagtcaggt
    25621 aaatgaacta acctggcata ccgttttcta ttcatctaac aatgttttca agaaataatt
    25681 gatgccttta gcacgactga aatgaggtca aattgacaga atactcctat tatggtacta
    25741 tttttaataa gaatattcag tgatagtgat aaagaggaaa atatgggaat tgaaaagaca
    25801 gttagtgaac tagctgatat tttgggagtg agtcgtcagg ccgtcaataa tcgtgttaag
    25861 tctttacccg aagaagatct tgacaaaaat gaaaaaggcg ttactgtggt taagcgcagt
    25921 ggtcttgtta agctggaaga gatctataaa aaaacaattt ttgacgatga gcctatcagt
    25981 gaagaaacga aacaacgtga gcttttagag attcttgtgg atgagaagaa cactgaaatc
    26041 acgcgccttt atgagcaact caaagccaaa gatgctcaac ttgcctcaaa agatgagcaa
    26101 atgcgtgtta aagacgtgca gatcgctgaa aaagataaac aattggatca gcagcaacaa
    26161 ttaactgcta aagccatggc tgataaagaa accctaaaat tagaattgga agaagctaaa
    26221 gcagaagcca accaagctcg cttacaagtc gaagaagttc aggctgaagt tggccctaaa
    26281 aaaggctttt tcacccgctt gtttgcgaaa taatcacaaa aaatgacgaa ggccctatca
    26341 gggtcttttt tggaggaaaa catgaaacac ttagatactt atattgcctt tgatttagaa
    26401 tttaacactg tcaatgacgt tagtcatgtc attcaagtat cagcagtcaa atatgaccac
    26461 cataaagaag ttgacagctt tgacacctat gtttacacag atgttccctt acagagcttt
    26521 atcaatggcc taacaggaat cacatctaac aagattgctg cggcaccaaa agtagaggag
    26581 gttatggctg cgtttaaaaa ttttgtggga gagttaccac tgattggtta taatgctcaa
    26641 aaatctgacc tgcctattct agctgaaaat ggcttggatt taagggacca ataccagatt
    26701 gacctctttg atgaagctta cgatagacgt agcgcagact taaatgggat tgctaacctt
    26761 cgtctacaaa cagtcgcaac ctttttaggc attaagggtc gaggtcataa tagcttagaa
    26821 gatgccagaa tgacagcagc aatctataag tcttttttag aaacagatac aaacaaagca
    26881 tatctcagcc agcaagaaga ggtaaccaca gataaccctt tcgcagcttt gggagacttt
    26941 ttcgactaaa ggctctgcta tttttgaaaa ataaaaaaat ccctagggtt agcccttgct
    27001 tataacgcta ggtcatgtga taagctaggg acatatcaag agggagtcga gtgcacacga
    27061 atcgtttttg atcactaaat gatagaaaga aggtgtggaa atgtctcaat tctattcgac
    27121 tggagaactg gccaacttag ctggcgtttc tattcgaact gtccaatact atgaccaacg
    27181 tgggattttg attccgacag cattgacagc aggtggacgg cgactatata cggattctga
    27241 tttagaacaa ttacgcatga tttgctttct gcgcgatttg ggattttcca ttgagcagat
    27301 tcgcaaagtc ttagcagagg aaaatgcagc ccaggtgctg gaattgcttc tagttgatca
    27361 tattgcgact gccaaggaag acttggccgc aaaagagcaa caagttgaca tagctgtcaa
    27421 gatacttgac agacttcgaa aacaagaccc ccagtcacta gattttctga tggacatttc
    27481 gcttagcatg aaaaatcaaa aagcttggaa aaaattacaa tggaagatgg gtatcagtat
    27541 atttttagcc attgtttcat atgtaggact tattttacta tctaattatc tgcaaaaatt
    27601 ttggttagtt tatgttgcta tgggaatatt tctaccaggt ttcagttggt tggtaattta
    27661 ttttaggaag caatttattt atctctgtcc ccattgtcat cagaaatttg aacctagctt
    27721 taatgaattt gcccttgcag gccatacacc acgaaccaga aagttaacct gctcccattg
    27781 ccatcaaaaa tcgtattgct tggaactggc aaaagaggac actgtctcaa gaggataagc
    27841 actaactcat aaaaaaacta gcctgagatc cttctcaagc tagtttttgt ttttttagaa
    27901 tggtaattta ccagcaaaag cgcctaatgt tttcttagtc gcttcatcaa tttgcgtaag
    27961 ggcatcatta atggcttgag tggtcatgtc ttgaagcgtt tctacatctt caggatctac
    28021 aacagcttct ttgaagtcaa tcccaaccaa ttttttatca cccgtgaaag tggcagtgac
    28081 aaggtcttga gctgattttc cagtaaattg catagcagcc aaatccgcct gcttttgctc
    28141 catttgtttc tgaagctttt gtgcttgctt catcatgttt tgcatgttca tcataagact
    28201 atactctcct taatttaata ctaactatta taacatataa aaagaggcaa taaaaacaat
    28261 gtcagttagt agactagcct gtatcagtaa gaaagtcgct atggataaga tggattagca
    28321 gcaagggtct ggctaatgac agaataagtc tagaaatgga ttatttttgt catagactag
    28381 tccgacttag tggttatcta attcacgatc ttctttagct tgttgttcta aaagaatttg
    28441 tgcgaagtca acccacttag tgtagttatt ttcggataat tgttctgaaa tcatcgctaa
    28501 ctctcgttgt ggcaactgat aagagactcc cttactttct aaggttaaat cttcttccat
    28561 tagggcggtt aaactaacat caaagatagc agcaatatca cttaatagac cagactttgg
    28621 agtatatttt cctttttccc actcactgat tgaagaagag ctttttcgtc ctaggagatt
    28681 agcaagttct aattgttcca tgttcttttt taatctaagg tactttaaat tacttgcaaa
    28741 aaaagttttc ttggcggaca tatttttctc cttttcttta tataaaatat gataccataa
    28801 aagaggttaa agcaaaaggt atcgtaaaag atggtctaaa aactctctaa aaacttgact
    28861 tcataaaaac cgaagtttat aataaactta acatgattaa ctaatctcat tttagtgtgg
    28921 agggaaaatt gtgaccaaat caactttaaa agagttaaga acaacaaaga aaatgacaca
    28981 gcaggaattg tctcacttaa caggcatttc tgtcagaacg attgctaggt atgaaaaaga
    29041 tactaaaaag ctaaggcgag caaaatatga gaagctaaaa ggtattgcac aagcattagc
    29101 ggtttccgtt gatgatattt ttttaggaat agattcggaa tttatgaact aagacgatcg
    29161 ttttctgttt gctattagta agaccaatta acaaaaaagt gcttagttat attgctaagc
    29221 acttttattt gttaatttga tgctattggc acaatcaatt gagactgact gagatcgata
    29281 gttaaagcat agttgctgtt gtcacggaca gtatgttcaa aatcggttgt gtataagatg
    29341 actcgaaggg tatctccttt ttctagatga tagatagttg gttgcaaagg aagtctaaca
    29401 gtcatccatt tattattagg aatagtttca attgacgaca aattattgcg attttgtaaa
    29461 ttcatgaaac ctttcgaaat aacacggtaa gaatcttctc taaatggtag ctctttaagg
    29521 ggttctctag agaaattttg cccattgtca atacttgatt gggtgagagc aataggaaga
    29581 tcgcccaagc gttttttctt accatagtca aggatttgtg cagatagaag tcctttattt
    29641 tcacttgatt tcacttttaa ctgtaggaca atttcaccgt taataggtaa gtcctcttcc
    29701 agtaaaatat caatcagggc ttgattggcc ttgcctttaa agagagctgc tttggacgca
    29761 cggaaatctt taccgtaagc tttaaattca tcttcaccat agtgattatc aattaaaagc
    29821 agttcctgac cgaggtcaag ctctttgatg gttgaggttc caaagacttt acgctcctgc
    29881 cagttttgtg ggcaggtgtt atcctgccag atcatttcag gaaggctaaa atcattagct
    29941 aggcctaaga gtttttgaca taaaagggca ttcatgcttt cgcgaaaatc aatggattgc
    30001 caattatgca tgtaaacatg ctcaccttga tgtaaaaaga ggtgcttgtt gattgtggaa
    30061 ggaagcgcat tgaaaatctc atagacctgt cttggtttga cattccagtc ttgtaagcca
    30121 tgagtataaa cgacatcaca ctttatttga tgagcatttt ttaagtaatt gcggtcgtgc
    30181 caaaattgat tataatcacc agattgtcgg tctaacgcct gagactgttg gtttagcaat
    30241 tcttgataat gatcattatg gcgaagataa tcgccagcca ataaattacg cgagtaggtg
    30301 agctcagtta ggacatctag atcctctcca ggatagccac caggactaca aactaagcca
    30361 ttttcgcggt agtagttgta ccaagaagaa atagctgatt ctgcaataat catggctaat
    30421 ccgtctacgc ctgtagtggc taaaccagta gacatagttc ccaagtagga ctttccagtc
    30481 gtacaaacta gaccatttgc ccaatcagct ctcacttggt gggtttttga gtggctggtg
    30541 taggctgtgg ctcttccatt tagccaatca ataacggctt taaagctttc aatttgagca
    30601 tagtctccac tcgtcataaa gccagtggaa ccagcagttc ccacacctga aacatagata
    30661 ttagcaaacc cacgtgcgag gaaataatcg ttgaggctat aggagttgat gtagctaaag
    30721 ctttctagat tttgacctat aggaagtttg caaggctgtg tctcaagagg aataaaatcc
    30781 ctgtcttcga cagtgatttg tctccttttt ttaacgacta actctttttc catacgataa
    30841 agttttttgt cgttggctac ttcattgata ccttgatggt atggactagg tgtcatcaaa
    30901 gttggtaatg gtttttgaga ttgaggacga atgatattaa ccttaataag atcaagttgg
    30961 ccatcttgat cggtatcaag aggtgcttca acgtaaacaa cttctcgaat cagctgtgac
    31021 gtgtcaaagg tagctaatga tttaccgttg aagaaatggt aatcattgtc catagtaagc
    31081 attccttggc tgaccaaatc atcaatcagg gtcatgccag acttacaacg ggtcgctaat
    31141 aagtggtgga tatgcttgat aatttctgtt tcgtcaaagt ggataggaaa ggccagttta
    31201 tcaaggaaag catcggcctc tgtaaaatca actccaggaa taaagccaag gacttgcagg
    31261 gccagtaaat caaaaacctc tttggataac tcttgctctg attgaaaaaa gctcaatgcg
    31321 tccatgtcat ttttggcgat tagatgactt aaaggataat cactatcagg gtagtggaag
    31381 aagagtttac gtaaaaagct ttctaggtta gctttggcag ttttttgcag atccagatca
    31441 aagcccaatt cttttaattc ttcagccgct ctttctagac tagttggaat ataggaaaat
    31501 tgattatagc gcataggagt ttcctttcta gtggcttaga aaacgatatt atcttttaat
    31561 ttatcaagat tggtaatgat aatatgttgt ttatcaatgc gaatgatgtt tttttctttc
    31621 aactgtttta gaatacggct gacgctgcta gcggtagaaa tgccacagaa tttaccgagt
    31681 tcctcattag taatgacaaa attaattaaa atttgaccat ttggtagttc ttcgccaaat
    31741 agggtcatta agtcatatat ttgagtagaa atggcaccga tacggccgtt agttaacata
    31801 cattgcattt ttttcatgga tttttgaaga cgattatggt aaaagtcctt cacatatcct
    31861 tgtagttcaa tatcttcgtt tatatctttt aaaaatgctg agcggcgaac cttgtaaaaa
    31921 ctagctttct ctgactcgat gcgaacatta taaggctctc ccatatcttt tgaataacca
    31981 gtgttgagaa cagaagtaat ttcaagtcct gtaacatatc tcaaattaaa ttccattcca
    32041 tattttgaaa gaacactctg tttcacaatg ccgtctttta aaatataagt gaagtcctct
    32101 tcgagacttt caaaagtcaa gtacttgtga taactttttt caatgatagg aaagttatga
    32161 ttatcaatat accgttgcaa aatgtgatga ttcacgcttt tctccaaata ttcttttacc
    32221 aatgtataat ttgtatcttc aagagaaatt aacatttgct aatgcccttt gatagtaaca
    32281 cttatattat accattgaaa tatattatat tctgcttttt ttgtaaaatg tttatgaaaa
    32341 tagagaggag ttcattttca atggaagaaa aattgtttaa caaacatttt gtggccatca
    32401 cagtaataaa ctttatagtc tatatggtct actatctttt tacggttatt attgcctttg
    32461 tggcgactag agagctagga gctcagacta gccaggcagg attggcaaca gggatttata
    32521 ttctagggac tttattagcc cgtttgattt ttggaaagca gttggaggtg tttggtcgtc
    32581 gtttggtttt aagaggaggt gctatttttt acctcttaac gaccttagcc tacttttata
    32641 tgccaacgat tagcatgatg tacttggttc gtttcttgaa cggatttggt tatggtgtag
    32701 tatcaactgc gacaaatacc attgtaacag cctatattcc agctcgtaaa agaggagaag
    32761 gaattaattt ttatggcttg tcaaccagtc tagcagcagc tattggccct tttgtaggaa
    32821 cctttatgtt ggataatctt catattgatt ttcgtatggt tattgtctta tgtagcgtct
    32881 tgattgggtg tgtggttgtt ggtgcttttg cttttccagt caaaaacatg tctttaaatg
    32941 cggagcaatt ggctaaaacc aaatcgtgga ctgtggatag tttcattgag aaaaaagcct
    33001 tgtttatcac tgcaatcgcc tttttaatgg ggattgccta tgcttcagtt ttaggatttc
    33061 aaaaattata cacgtctgaa attcatttga caacagtagg cgcttatttc tttgtggtct
    33121 atgccttaat cattaccatc actcgtccag caatgggacg tttaatggat gctaaaggcg
    33181 ataaatgggt cttgtaccca agttatcttt ttttagcaat gggactcttc ttgctaggta
    33241 gtgtatcgtc tggaggaagc tatttgcttt caggagcctt gattggcttt ggttatggca
    33301 cttttatgtc ttgtggtcaa gccgcctcca tacaaggagt ggatgagcac cgctttaata
    33361 cggctatgtc tacttatatg attggtcttg atttaggttt aggtgctggg ccttacctct
    33421 tgggcttgat taaagattta gcacttggta gtggtgtggc ttcctttagg cacttattct
    33481 ggttagctgc tgtgattcca ctgatttgta ccttgcttta cttgttaaaa acaaagacaa
    33541 gacaggttgt gtcttaagga caagaaaagg agtttagtct tatacttaaa tacaaacgta
    33601 tcttaacagc tgtagatagt tcctatgagc cgggattagc tgtgggtaaa gccattacta
    33661 tagcgctttg aaataattct agtttgctat tcgtacatgt caataaaaat gactcgcaaa
    33721 agccattcgt gaaagagaaa atgtggcctt atttttagta ggtgcaattg gattaagcac
    33781 gtttagatac atgacaattg gattaacatc agaatatagg ctttgtcatg ttaagattga
    33841 tctgttgata gtgagagcta ataaaaaatg ttataatact atgaaataaa gtgataaaga
    33901 taaggccttt tatggtcctt ttctttaccg cttttattat tgtgtgaaaa taacacttaa
    33961 tgatcatttt atttattatt ttattacctt tacattcatc aataagcctg ttaaaatggt
    34021 atttgttata ttttattatt tggaggaaac cagaaaacat ggaaatgaca tggactgtga
    34081 aatacatcac agaatttatc gcaacggctt ttttgattat tttggggaat ggagctgttg
    34141 ctaacgtcga cttaaaagga acaaaaggac ataactcagg ttggttagtg attgcttttg
    34201 gctatggctt aggagttatg atgccagctt tgatgtttgg taatgtatct ggaaaccata
    34261 ttaatcctgc tttcacagtt ggactagcag tatcaggctt gttcccatgg gctcacgtct
    34321 tacaatacgt tgtggcacaa ttacttggag ctatctttgg tcagttggta gtggtaatgg
    34381 tttataaacc ttactttatg aaaactgaaa atccaaatca tgttttaggc tcattctcaa
    34441 cgatttcatc tcttgataat ggtcaaaaag acagccgtaa agcctcttat atcaatggtt
    34501 tcttaaacga atttgtaggt tcatttgttc ttttctttgg tgctttggct ttaactaaaa
    34561 actactttgg ggtagagtta gttggtaaat tgattgaagc aggctacgac caaacaactg
    34621 cagcaacaca aatttcacca tacgtgacag gctcattggc ggttgctcac attggtattg
    34681 gtttcttagt tatggtcttg gttacttcat taggtggacc aactgggcca gcactaaacc
    34741 cagcgcgtga ttttgggcct cgtttgttac accacttctt accaaaatca gttcttggtc
    34801 aagccaaagg tgattcaaaa tggtggtatg catgggttcc tgtagttgca cctatcttag
    34861 cggcgatagt agccgtagca gcgtttaaat acctttatat cagataaaaa aagaactaaa
    34921 gcttctttta gactcaagac aagctcgctt aaggaacttg tcttttttag atgagttaag
    34981 cgaaatctaa tgcaaacttg actgtcttgt atagcgtatt ttgtaaattt tattagactt
    35041 cttgtaaaaa agcctctcct cagataagat gactagtgcc tctaaacggt gttacaaata
    35101 aacgaggcat ccctaacttc ctttatctgg tgttgaaact attttgcacg gactaaatca
    35161 ctgacagagt aaaaaacgat ttttcatttt tgttgtaaaa tattaaaaac gtctctggtt
    35221 agtgattccc agaaacgtta tcttatctat ttgtttgttg cttatgagag gtaaaggagg
    35281 aacgaatcag cattccacca gtgaagaaaa cgatagcgat gaccagaagt ttcaagctat
    35341 taatatctaa atttgttaag aaaaacacag ctagtaaaac gccaataata ccaccagaaa
    35401 caattccagc aaaaccatcc caactgacac ggtttgcttt gataaactgg ctactagaag
    35461 ctgtcataat catagctgca tctagcatca taacaggcat agcaactgtt gggctaagac
    35521 ccattaatga aaagaaaatc aattctggag cataattgcc taaccccata gtcatcaaga
    35581 ctccaacgat aaaattaaaa ccaattccaa caaaaagcca gatgccatgg aggccatgaa
    35641 tggtgtctga aaggtgttct cctggatggt agattattct aatgatcatg attatagctg
    35701 ctatgattaa aagactacca aggattcgtt ggacagttgg agcatgccag ttttttgtaa
    35761 tatgagtccc aaaataagct ccaataaagg ctgctgcagc catagcaagt aaagttagaa
    35821 cctcaacttt tacgacaaaa ataaagcaaa gagattgaat gagcaccgga agcacatgag
    35881 ctacggtcat agtgccaggc aattgtctat cgtcagtgac taatttagtt aacttaaagc
    35941 acgttgtggt agtagcaaaa gaccctatcc caagggtgtc aagggcatct gttagcaggc
    36001 caatccaaaa ccccgtccaa aagcgtttaa aaggattgat cttatttttt ttaagatgtt
    36061 ttactaacat aaagaaaata aaaagcattg ccgaaactag caaagcttgt atcagtctaa
    36121 ggataagcat ttcgttcata aagactagtt tacaaaaaaa aaccttagcc gtcaacgtga
    36181 tttacttcat taaaacatgc cactatgctt agaagagctt tagttcgatg tattttgtta
    36241 aaattaagct aaaatattaa tattgcatga aaggggacgc cttccttttt cccttactga
    36301 gcttagctgt tattgtagtg aatgtttaaa aggctagttt gtcgctcttt atcaaaaatc
    36361 tagtaggatg aatacgtata atttcttgtc aaatagagga attttgtcta taatagcaga
    36421 ggattaggag gaaattatga ctttaatgga aaatattacc tttaaaactc cagtattacg
    36481 cgttaatgat cgcgacctta atattgcatt ttatcaaaat aatttagggc ttcgtttagt
    36541 atctgaagaa aatgcgattg ctatcttttc atcttgggga gaagggcagg aatgttttgt
    36601 aattgaagag tcaccttcag ttagaacgcg tgcggtagaa ggccctaaaa aggttaatac
    36661 gattgtcatc aaaacaaatc aacctaaaga aatcgaacaa ttattagctc atggagcaca
    36721 ttatgacgct ctttttaaag gtcaaaatgg ctatgccttt gagactattt ccccagaagg
    36781 agaccgattc ttgttgcatg ctgaacaaga tattaaacat ctccaaggta ctgatttacc
    36841 atcgcttgaa aaagatgcga cttttaaagg tttaactcaa tttaagtttg atattattgt
    36901 tttaaatgtt attagtgaag aacgctcaaa agctttttat cgggatctgt ttagtgatca
    36961 gttacctatt actatggatt ttattcaaga agaaggtccc gatttggcaa ttgatcccca
    37021 tattgcttgg gatttagaaa ttttagaatt tcaagtctca aaggactatg atatgaaggt
    37081 cctaaaagca actttagaag aagacgggca caaggtctac attgataaaa aacacaaagt
    37141 attggtcctt tctgatccaa gtcagatcga agtatggttt acgaaatgac tttggcagtc
    37201 attaaatgta ttgaaaacca tcttcacaaa aaagtataca aaggggccag tctggctctc
    37261 tttcaatctg gtcgatggca agaataccat atcggaacaa ttgatggaag acgaccagtt
    37321 gatgctaact tagtttatga cttggctagt gtttcaaaag ttgttggtgt ggccacaata
    37381 tgcaatattt tattgaataa tggtacgtta gcattagatg atcccttaaa agtatattat
    37441 cctagtattg ctgatacgac tgtcactatt cgacagttat tgactcatac cagtggtctt
    37501 gatccttata ttcctaacag agatgtttta aatgcacaac aattaagaaa agcacttaat
    37561 catcttactc aaaaagaaaa taaaaacttt tattacacag atgttaattt cctcttgtta
    37621 ggctttatgt tagaagagct ctttagtgaa tctttagacc agatatttga taagactatc
    37681 tttactccct ttgggatgta tcatacgtct tttggccctc gtccagaagc tgtaccaaca
    37741 ttaaagggtg tgagtgatgg agaagttcat gatcccaaag caaaaatctt aaaaaaacat
    37801 tctggatctg cggggctatt ttcaactctt gcagatttag aaagttttag caatcattat
    37861 cttaatgatc cattttcaga ttgtctgtgg cgcaactaca gccaacaaac aagtgagcgg
    37921 tcactagggt ggaatttaga tggcgattgg attagtcata caggttacac agggccgttt
    37981 ctaatgctta ataaaaaaga gcaaacggca gctatttttt tgaccaaccg tacttacgac
    38041 gaggatgata aaagtaaatg gttaaaagaa cgtcagttgc tttacaatgc actaaagcat
    38101 gatctgacaa cacccgtatc gtaacgtcta aaggggcagt tttagtgatc ttattactgt
    38161 ttttaaagtt tcttctaaaa aatagccatt tcatttgtct gatgcgatta gagtgattat
    38221 aagtgaaaaa agaacagcca tctcattttg aatcaaatga gatggctgtt cttttttata
    38281 agttattgat catttagata ctactattta cttgaaatag cttcagcggc atcatccatt
    38341 gaaagcactt cgtggaagac acgttgagtc aattcagttt tttgttctgg tgtaaggtat
    38401 ttggtgttga cacagtaacc agagatacgc acgataacgt cttcgccgtt catgattttg
    38461 tcataaacat cgttaaggtc cataacgttc aagttaacgt gttgaccacc attttcaaag
    38521 taaccgtcaa gcactgttac caagttgtca acttgttcgt caaatgtttt accaagagca
    38581 cgaggtgata cttgagtagt caatgagata ccatcgttag catgtgagaa ttccagttta
    38641 gcaagtgagt taaggttttg taaccagcca ccttttgctt tgttagatgg gttagcacct
    38701 ggtgagaaga attccacttg gctagtgtta actgtaccat cttcgttcaa gaagacgccg
    38761 cggtgaactg gagagttacc agtttgttta gagtaagcaa cgtttgaagt gatggtaaga
    38821 agtgatactg aagcctcagc attcttgtaa agtttgtggc ttgcaagacg tgtgtggtaa
    38881 gcttccatca accatttcgc gatgtcatca acacggtcgt catcttcacc gtaacgaggg
    38941 aagtcacctg ttacttcgta gtcatagatg tagccatttt catcgcggat agttttaaca
    39001 gttgcgtatt taatagctga caaggtatca actgtgttag cgaaaccaca gataccgaat
    39061 cccatgttag cacgttggtg tgttggcaag aaggccattt gaactgcttc gtagttgtat
    39121 ttatcagtca tgtagtggat gatgttaagc gcatctacat aagtatctgt caaccagtca
    39181 agagatttct caaagttagc cataacttcg tcgtactcaa gaacttctga tgtgattggt
    39241 tcaacaacgt taaacacttt gtagtctctg tgaacatcat cgtaaccacc gttaagacca
    39301 gtaagaagag ctttgagaac gtttacacga gcaccgaagt attggatgtt atgacgttgt
    39361 tcttcatttt ctgggtcaag tggtgataca caacatgaaa tacatgacat ctcaccataa
    39421 ccttctttag ccattgttgt cacaccttca tattggatag aagagtgttt gtggctcatt
    39481 ttcatacagt agcgacggaa tgtttctggc agttggtcag tccaaagaac tgttaagttt
    39541 ggttctggag agttaccgat attatcaaga gtgtttaaga aacggtagtc catcttagtc
    39601 acacggtgac gaccgtcgtt acccatacca gccatagaag ttgtgatgaa tgttgggtca
    39661 cctgagtaaa gggcatcgta agctttcgta cgaccaaatt ttacggtacg gagtttaagg
    39721 acaaaatcat caacaaattc ttggatttct gattctgtaa aggtaccgcg agcaaggtca
    39781 cgttctgcaa agatatcaag aacgattggc acacgtccaa gagaagtagc agcaccgttg
    39841 atcacacgac atacagccat gaaagcgatg tttacccatt ggatagcttc tttaacgttt
    39901 tgtgctgggc gacgaacatc aactccgtaa aggtcaccaa gtttaaccac ttcaccaaga
    39961 gcttggtatt gaaggttaac ttcttcgcga agacgaatgg attcttcatc gatttcagtg
    40021 atagcattcc agtcattgac tttttcttgc atcaagtagt cagcaccgta aagagcaaga
    40081 cgagcgtaaa caccgatgat acgtccacgt gagtaagcat ctggaagacc agttacagtg
    40141 tgggcatgac gagcgcgacg aatatttgaa gtataagcgc ggaagatacc gtcgttaaca
    40201 gttgtcacat acttagtaaa gatttcatgt actgctgggt ctggttcata gccgttttct
    40261 ttaagggtcg tttccgccat acggatacca ccttttggca tgaagttcaa tttgaacaat
    40321 tcatcgtttt gaataccata aattaattca ttttctttat cgatgaaacc agcaggaatg
    40381 tcagcaattg aagttggacg agtatcgtat gggaaacgtg tagcttcata gtgtgctttt
    40441 gtttcttcga taactttttt gatgtgaagt gaacgttcag tagcaccagc caagaaagat
    40501 tcatcgccat cgtatggggt gtagttagct tgtacaaaac gtgagacact tgctttttct
    40561 ttccagtcag ttcctttaaa gccttcccaa gctttttcga aaacatctgt attggtttta
    40621 acagttgcca taaatttctc cttaaattct agtaacaaag cgatctgtta catttacaat
    40681 tctaagttta acacatagga aacgttttcc caagcaaaat tcttgacaaa attaagattc
    40741 ttttataata cagattgttg aaacagtcac aaactgtatt agaatgtatt tttttggctt
    40801 tagatagcct aaaaggtata atagagaaag gagggactta tgcttatttt tccactgatt
    40861 aatgacacgt cacgaaaaat catccatatt gacatggatg ccttttttgc tgcagttgag
    40921 gaaagggata accttgcttt aaaaggaaag cctgttgtga ttgggaaaga tccaagagaa
    40981 acaggtggtc gcggagttgt ttccacttgt aattacgaag cgagaaaata tggcattcat
    41041 tcggccatga gctctaagga agcttatgag cgttgtccca aagccatttt tatttcagga
    41101 aattatgaaa agtatcgaac agttggggag cagatccgcc gtatttttaa gcgttatact
    41161 gatgtggtag agcccatgtc cattgatgag gcctatctag atgtcaccaa caataagttg
    41221 ggtataaaat cagccgtcaa aatagccaag ctgattcagc atgatatctg gaaagaagta
    41281 ggattgacct gttcagcagg tgtgtcttat aacaaatttt tggctaaatt ggctagtgat
    41341 tttgaaaaac cccatggcct caccctagtc ttgaaagaag atgccctgtg ctttttagcc
    41401 aaactcccca ttgaaaagtt tcatggtgtt ggtaaaaaat cagttgaaaa actgcatgac
    41461 atggggattt atacaggaca ggatttgttg gcagttcctg aaatgacctt gattgatcat
    41521 tttggtcggt ttggttttga cctttaccgt aaagcgagag gcatcagcaa ttctcctgtc
    41581 aagtctgatc ggatacgcaa gtcaattggc agtgagagaa cctacgctaa actgctttat
    41641 caagaaacag acatcaaggc agagatcagt aaaaatgcta agcgcgtggc cgctctctta
    41701 caagaccata aaaagttagg caagaccatt gtgctcaaag tgcgttatgc tgattttacc
    41761 accttgacaa aacgtgtcac cttgccagaa ttaaccagaa atgccgcaca aattgagcaa
    41821 gtagctgggg atatttttga cagcttaagc gaaaatcctg ctggtatccg cctgttaggg
    41881 gtaaccatga ccaatttgga ggataaggta gctgatattt ccttggacct ataggagaaa
    41941 gagcgctcta tccgtccgcc tcattttgga gaaaaaagaa gctgattagg gatttcccta
    42001 atcagcttct ttggtccatt attttattac agcatagctt ggtctgtatc atcacctttt
    42061 tcgttaaggg tttttgcttt gtaaaaagca aagccataaa gagcagcttg tataaggata
    42121 aggatagttc caaccattga caaggttgtt gtgaactggt taaccaagcc gataacagaa
    42181 aggataagtc ctaatatgta aggaatataa ctaaccgtta atccttgttt tagtttggat
    42241 aagttctgag tacagaagat gataattgca ataatagcaa ggacatttaa gacagataag
    42301 aaaatcataa atggtgtcat gctgctttgt agctgtgcca attgctcagt tgttaattgg
    42361 gcccgaaatg cttcattctt gagttggctt tgtaagtaga aaaaacctgc aaatcccatt
    42421 aatgacagta caactccaag cccgtttaga ataataatgg caatagtaga cgttttgagt
    42481 gcctgacgca ctttttcata agaaatcata taatcctcct agagtcctta atccgaaatt
    42541 gtacaatgtg tttaatacaa aaatattata ccatagatta atcaaaaatg tccgtttttc
    42601 taggattttt tctggaaaaa gagggcaata tctgactctg taagccctat catcgaatcg
    42661 atagtcgaat aattctcagg tgttaaccta aaatcatcat tatctgactg agagttctca
    42721 gtggggttag agtttgttga ttgagaggaa gatttttgag agtcgtcctc aagggttgcc
    42781 gtattagaaa aaagggaggt ctgctctttt gattttagct cttggttagg ttgagaggag
    42841 gctaagtcgg attgttcttg gaagcgttcg atcaagtagg tttggcgttt atcgccttcg
    42901 tgtttaatag catactcaaa ggcagtatat tctcccaaca gaattaactt acttttagac
    42961 cgagtaatgg ccgtgtaaat cacatttcgt tgcaagagtc ggccgctttg gcgtgtgata
    43021 ggtaaaatca ccacttgaaa ctcactccct tgcgatttat gaatgctcat ggcataggcc
    43081 agggttaatt ttagccattc atttctaggg tacgtgactt cgctaccgtc aaaatctaag
    43141 attaattcgt cttgtttaga ttcggtgtat ttagcaggaa tcaaatctgt aatataacca
    43201 atatctccgt taaagacatt caactgagca tcgttgacta agtgcaggac tttatcacct
    43261 ttacgaaaat gcgtatcatt gaacagaaat tctgtttgtc cttgcaaggg attgagaagt
    43321 tcttgcatga gttgattaag atgattgatg ccagcttgtc ctttgtacat aggcgctaaa
    43381 atttgaattt cctcagcagg gatgccactt ttaatagcag ataggacaat tttttgaatc
    43441 atgtcaggga taaaggctgc ttgggcttca aaataagaac ggtcagcttt tttatcacga
    43501 aagtcagcag ctaagattcc tcgacgcatc tgatctgcca aattgacaat agtagattct
    43561 tgggattgac gaaatatctt ttgcaaggcg atttggggca ggctattgac ttttaaaaga
    43621 tctgacagga cttgaccggg tccaaccgaa ggaagctggt cactatctcc gacaataatc
    43681 acttgagttg ttgagttaat cgctcctaac aactggttgg caagccaggt atccaccatt
    43741 gaaaattcat cgacaatcag caggtcgcag tctagataat cctccatggc ttggtaatcg
    43801 ttgtcgccat tgaggcctaa gtgcctgtgg atggttgcgc taggaagtcc agtcaactca
    43861 ttcatgcgac gtgcagctcg acctgttgga gctgctaaca agataggaag gtctttttta
    43921 tccaaatcaa tctgatgcag gttcgcgtaa gcctgcaaaa tgcctcgaat aacagttgtt
    43981 tttcctgttc cgggaccacc tgttaggaga aagaccttgc tggttaaggc cttagtaatg
    44041 gcttcttgct gcacttggtc ataggtgatg gcaaagtctt tttgaacggc ttggatggtt
    44101 gtttgaatgg tatcatgact aaatgactga cttaaagggg tatctaagag acgagagatg
    44161 ttgctagcaa tcccttcttc agcaaaataa aggctagcat caaacagttt ggtgtcactg
    44221 tttttgattt tgccctctat gatcaactcg cttagttgtt cagccacagc agcaggatca
    44281 cattctactt gacgtgcatc ttcaaggagt gtgatggcaa agtctaataa ttgtcgtgct
    44341 tggacataag tgtctcctcg actgacggat tcttccaaga ggcagtgcag gagggcagca
    44401 cgaaaacgtt ttggagagtc gctctcaatc cctaagtttt cagcaagagc atctgccatc
    44461 ttaaacccaa aaccttgtag atcttcgact aattgatagg gattttcttt aacaaggtca
    44521 agagcctctt ctttgtactt ctcaaacgct tgaaaggcaa aacggttgct aaggccaagt
    44581 tcgacgagac cagcaatcag ttgctctgtg ccataattca atttcagttt agcgacaaag
    44641 gcttgacgat tagccttgga cagaccagag atagtttcta atttgcttgg gtcttctaaa
    44701 atatggtcaa tggtattatg accatatagc gcaatgattt tctccgctgt ttttttacca
    44761 atccccttaa aatggtcact agagaaataa ttaaccaaac cagatgaact aggtttgatt
    44821 ttttggtaac ggcttagttt gagttgctgt ccatatttag ggtgctgggt caattctccc
    44881 caaaaggtgt agtcatctcc ttcaataatg tcagccatcg ttcctgtgat aatgatttca
    44941 aagtcgtcaa tgtcactgtc tgtatcctca atggcaagga ggagaatttt aaagaaatta
    45001 gcctggtttt caaaaatgat acgatcaaca gtacctgtaa aaacgtattc catagtaact
    45061 ctttctattt atacaagata actgaaaacc tgcccaaagg caggtttttt ctaattaaaa
    45121 acggtcattt tattgagtgg ccaaaaacga gctttcactt caccgataag gttttctttt
    45181 ttgaaactac caacttcgcg actatccctg gaaacaatac gatcatcacc aagaagaagg
    45241 tattctcctt ttggaacact catctcaaag cgtgtttgtc cctcagaatt agttgtaaaa
    45301 gcatcagatg tttctgctaa ctgttggaat agggtattat aggcgtaagt tttttggagt
    45361 ttatcgtttt taaattgttt tagatactca gccaaatacg gctcaactgt ttttttacca
    45421 ttaatataaa gtgtgtcatc attataagaa atggtatcgc ctggcaatcc aataactctt
    45481 tttacgattt ctttcttttg tccattttct tcttcctgag caactacaat atcaaagcga
    45541 tcaatcctag cttgattaaa aacgataagg cgttcgccat gagctagagt tgggtccata
    45601 gaatggccgt ctactttaac agcctgccac aaaaaaagac gagatagacc aaagagaatt
    45661 aaaaagagag tgaatgggcc ccattcttta ataaactgtt tcatatgatt ccttttattt
    45721 agtgagaagc gcttgcgctt tgtgagtgtt ggcgaagtga agtttagcac tatattctaa
    45781 gctagacata ccataagcgg ctaagagttg gctagcaact ttatctgaag ctgaaccagc
    45841 accgcttggg agttggtaac ctaaatcttg acctaattga tcgagattgt ctaaaaatag
    45901 atttctagca atgatagagc taacagccac agccaaatag tgactttctg ccttttcttg
    45961 aaaggttaga ggatttggga aatggttttt ttcctttttt agatgctttt cataatttga
    46021 ttggctagtg aaagcatcaa taacaatttg tttaggttga atgccttttt gtaataacaa
    46081 aaaaatagct tggttatgaa gagcaacttt gatagaaatg gcattatatg gtttactttt
    46141 accaaccaat tcgttatatt ttttaggtga taggagaagt gactgatgag gtatttgttt
    46201 ctctaacaga ggcgcaatct gttgaatggt tttatccgat aattttttag aatcatcaac
    46261 cccaagcttt ttcaggaagg aatgatcttt aggatcgaca aaacttgcca caacagcaat
    46321 cccaccaaaa taagagccat tacccacctc atcactgccg attataggta tatcttggct
    46381 attgttgctt gcttcaaaaa ctgtcttagc tactggaaga ttaagctctt gagctaaagc
    46441 atttgcaccg tttccctgga gaactaattt tccggatttg tacagcaaaa cagtaacccc
    46501 atttttttta gcagcaaagg ctacataggt attttggcta ctgatggtgt aggaggctag
    46561 ctgttttttt aaatgtttac tcagtatagc atctattttc aaaactaagg tattcataat
    46621 aattatttta acataaaata gttgactatg gttaattcat aagtttattt aacaaagaaa
    46681 acagagactc gaatgtttag acgggttagg gcaatggtgt tgactatttt acgaaagttt
    46741 cattttacgg tataatgcta atgaggtgac cctatgaaaa gtattaatcg ctacaaattc
    46801 acctttggtg aaaaaacatt aacattgaca actgacaaag acaatctctt tatggaagag
    46861 gttgagcggg tagctaaaga aaagtatcag gctcttaaaa atcatttacc agaagctgat
    46921 gacgagactg tcgctatttt aatggctatc aataccttgt caacacaatt aagcagagag
    46981 attgccattg aaaaaatgga agctgaaatt ttagatttac gtcaaaaaac cttggttggt
    47041 cttcaagaaa aagctaatca aatagatgtg aatgaggttt aatcatgtta tctttattga
    47101 tagttcttgt tttaacttgg aatttttata ttggttatag tagaggtatt attcttcaat
    47161 cgttttatgt cttaggagcc ctactttctc ttttggtagc taatcgattt tatattggat
    47221 tagcccataa gctaacgctt tggattcctt attctaaccc ggtagaagga acatcagtct
    47281 ttttctttaa atcagttgat atctttgttt tagataaggt ttattatgca ggccttgcct
    47341 tttttatcat tttcttattg gggtatgcat tgagtcgctt tcttgggatt tttgttcatt
    47401 tccttttgct agattatttt gataaccagt ggacaaaatg tttgagtggc ggactagcgc
    47461 ttctagtatc gcttcttttt ttgaacatgt tactgtctat ttttgcaacg gtccctatgc
    47521 cttttttaca gcactatttg cactctagtt ttcttgctcg tttggtgatc gaacaccttc
    47581 caccattgac aataattatt caaaaattgt ggattcaagc cattatttga tatcgttttg
    47641 tgactaatat aagaacctgg agtgagtttc acctttaggt tctttattta cgagaaactg
    47701 tttagaaata aagagaacgc atgggaactt agtgactttc ttgccccatt ttccatcatt
    47761 ttaggtataa tgaagagtat gaataacaag attttagagc agttagaatt taacaaagtt
    47821 aaggaattgc tattacctta tctcaagaca gaacaatccc aagaagaatt attagagctg
    47881 gagccgatga cggaggctcc taaaatagaa aaaagtttta atgaaatttc tgacatggaa
    47941 cagatttttg ttgaacatca ctcatttggc atagtcagcc taagttcaat ctctgagagt
    48001 ttaaaacgct tagagctttc agctgatctt aatattcaag aacttttggc tatcaaaaaa
    48061 gttttacaga gttcttcgga tatgattcac ttttattctg atttggataa tgtttctttc
    48121 caatctttgg atcgtttgtt tgaaaatttg gaacaattcc ctaatctgca agggtctttt
    48181 caagctatca atgatggtgg ttttttagaa cattttgcga gtccagaatt agagcgtatc
    48241 cgtcgtcaat taacaaatag tgaacgacgg gttcgtcaga ttttacagga tatgcttaag
    48301 gaaaaagcag agcttttatc agagaatcta atcgctagtc gtagtggacg aagtgtccta
    48361 ccagtaaaaa atacttatcg gaatcgtatt tctggtgtgg ttcatgacat ctcttcttca
    48421 ggaagtactg tttatattga gcctcgtgct gtagttacac taaacgaaga gataacgcag
    48481 cttagagctg acgaacgcca cgaagaaggt cgtattttac acacattttc agacttgtta
    48541 agacctcatg tcgccactat tagaaataat gcatggattc ttgggcatct tgattttgta
    48601 agggctaaat atctttttat gtctgataat aaggcgacga tacctaagat ctctgatgac
    48661 agcacgttag cattaatcaa tgttcgtcat cctctgttaa gtaatcctgt ggctaatgac
    48721 ttacattttg atcacgattt aactgcaatt gtcatcactg gtcccaatac tggtggtaag
    48781 acgattatgc taaaaacact cggtttagca caattaatgg gacagtccgg tttgccagta
    48841 ttagcggata aaggtagtaa aattacagta tttaacaata tctttgcaga tattggcgat
    48901 gagcaatcta ttgaacaaag tctatcaact ttttctagtc atatgacgca catagtcagt
    48961 attttaaacg aggctgaccg caatagttta gttctctttg atgaactggg agcaggaacg
    49021 gatcctcaag aaggtgctag tttggctatg gctattttag aacaccttag gttaagtcat
    49081 atcaaaacga tggcgaccac gcactatcca gaattaaaag cttatgggat tgagacaaat
    49141 tttgtagaga atgcgagcat ggaatttgat gccgaaacgc ttagccccac gtatcgcttt
    49201 atgcaaggag ttcctggacg atcaaatgca tttgaaattg cttctcgcct tggtttagct
    49261 ccatttattg ttaaacaagc taagcagatg acagattctg actcagatgt taaccgtatt
    49321 attgaacagt tagaggcaca gacacttgag acacgtagaa gactggatca tattaaagaa
    49381 gttgaacaag aaaacctcaa attcaatcgt gcggttaaga aactctataa tgaattttca
    49441 catgagcgcg ataaagagtt agaaaaaatc tatcaagaag ctcaagaaat tgtagatatg
    49501 gctttgaatg agagtgatac tatcttaaaa aaactcaatg ataagagtca attaaaacct
    49561 cacgaaatta tagatgctaa ggcacaaata aaaaaattag cacctcaagt tgatttatca
    49621 aaaaataaag tcttaaataa ggctaaaaaa attaaagcag ctcgtgcccc tagaattggt
    49681 gatgatatta tagtgactag ctatggacag cgaggtactt taactagtca attaaaagat
    49741 ggccgttggg aagcacaagt gggaattatc aaaatgacat taacacaaga tgaatttacc
    49801 cttgttagag tccaagaaga acagaaagtc aaaagtaaac agattaatgt ggttaaaaag
    49861 gctgatagtt ctggaccaag agctcgactt gatcttagag gtaaaagata cgaagaagct
    49921 atgcaagagt tagatcattt tattgatcaa gcattgctta acaatatggg acaagttgat
    49981 atcattcatg gtattggtac aggcgttatc cgtgagggag tgacaaaata tcttcgtcgt
    50041 aataagcacg ttaagcattt tgcttatgcc ccacaaaatg cagggggatc tggcgccaca
    50101 attgtaacgt tagggtaaat tatggaatca tatgaacaat tttatgccaa actatctcaa
    50161 ccttttagaa aatccccaca gttaataatt cttttaaatt ttttactaaa aatagtcaca
    50221 ggaatgatgt acatactcta tccatctttt ctgatattta cgctttggca agggatgaca
    50281 tttcaattat ggttaaggct attaattatc cctgctgttg gctttatagc tttgtcttac
    50341 attaggaaac gctttgattg tccacgaccg tatgaaaaat ggaatattaa acctttaatt
    50401 gataaggata caaagggaag gtcaatgcct agcagacatg ttttttcagc tacgatgatt
    50461 agtatgtgtt tgttacgata ttatgtttac tttggaatag tttgtttaat attatcggtt
    50521 ctattggcaa tttgccgtgt gatagcaggt attcactatc ctaaggatgt tattgtaggt
    50581 taccttattg gcttgatgtt agggctttgt ttattgattt agcgagttcg tagcaaatag
    50641 tttcaaaaac aactaaattc ttgtacaata ggcttatcat taagatgaaa tggagaaaaa
    50701 agatggcatt agaagtaaca gatgctacat ttgtagaaga aactaaagaa ggtttagtac
    50761 tcattgattt ttgggcaacc tggtgtggtc catgtcgtat gcaagcacca atcttagaac
    50821 agttatctca agaaatcgat gaagatgaac tcaaaatttt gaaaatggat gttgatgaaa
    50881 atccggaaac tgctcgtcag tttggtatta tgtcaattcc aacattgatg tttaaaaaag
    50941 acggagaagt ggttaaacaa gttgcaggtg ttcatactaa agaccaactg aaagctatta
    51001 ttgctgaatt gagttaacta aaataaagcc cagcgtcacg ctgagcttta ttttattatc
    51061 tactaacttc aatggaataa ccatgtaaac ataaaacgac ttgcaaaagc aaaagcaaca
    51121 gtaatgagga aaaatacagt gacaataagg ggtttctgat aaggaagttt tgctctttct
    51181 tctcgttttt cgatttcgtc taataatttt ccatttgaaa cagctaggat ttccttataa
    51241 ggttgcacat catatttttt cttaaaacgt tccacacgat tagcataagt catagtaatt
    51301 atcgataata aaacaaaaat gccaagtcct agccactcta agaaatagac taatggataa
    51361 cttgaaatca ttaatagtat catcaatgtt accattactt tggtatctcg tttaaaattc
    51421 tttttatcaa cctgagtgat ggtatatttc attttctcaa tgtctccttt aatgagttgg
    51481 tctaagctca cttgaaaaat ttgacttagg agtaagaggc tatggatgtc tgggtaagtt
    51541 ttgtcatttt cccagttaga tatgctctga tagcttacat agactttctc ggctaatttt
    51601 tcttgcgaga gcgcttgttg tttacggtag cgaataattt gctgaccaat ttccataaat
    51661 atcaccggaa aactttacag cggcgtaaag gaattgtaaa caaaaagtga accgttatag
    51721 ttcacttgcg attaagcatt tttctgtttt aagtaggtct ctagcatttt cttttgtggt
    51781 gttgcaaagg gatacagaga aaagtcctca attgctaccc actttaggtg aggagcatta
    51841 ggtaaatctg ttgctttgac caccccctct atgagttcta ttgtccactt ctggtgacta
    51901 aaagtgtgct taatatttgg aaagtgatta tcagtccatt ggggctttaa ttgatattct
    51961 ctttcgaaag tttcattttg ggtttgccag attatggggt tggattgatt gtcatcaaat
    52021 aaatctaatt gttgagaaag aggtgacgtt tcgataatag gaaatgacca aaaacctcct
    52081 agaagtctcc ctttagtatt tttctccagt agatattggc cattttggtt acgaatgaca
    52141 aaagcctgaa ttcgcattgg tttaggcttt ttctttggat tttttatggg gtatttacca
    52201 taagtaccat tcaaataagc agcgttaaag aaacgaatag ggctttcatc aggcctaggt
    52261 gtcttagcgg attcgatgtc tgtacctaga tccataagtg cctggttaaa atcaccgggt
    52321 ctgtcagggt caattagtat ttccataata gcttgaaaaa ttttacgatt tttagggtca
    52381 ccgatatcat aattaacttc aaacaaacga gccatgacac gcatcacatt gccatcaaca
    52441 gcaggctctg gtaagttgaa tgagatgctg gcgatagcac ctgcagtata aggaccaatc
    52501 ccttttaatg aagcaatatc atcataagtg tgaggaaata tgccaccaaa atcaaccatc
    52561 acttgctgtg cagccttttg catattacgc acccgagaat aatagcctag tccctcccat
    52621 gcctttagta attgttcttc aggagcgtct gccaaatctt ttatttgagg aaaccactct
    52681 agaaaacgtt tataataagg gattaccgta ttaacttgtg tttgttgcaa catgatttca
    52741 gaaacccaaa tatagtatgg attagtagtt cttcgccaag ggagatcacg tttttcttgg
    52801 tcataccacc ctaaaagtgt gcgacgaaaa gaagcgattg tctcattatc ccacatatta
    52861 ataccataat cttttaattc aatcatgttg ttattgtaac acaggagtct taaaaagagt
    52921 aaaaaaagat tttaggtatt tgcgaaaaag aaaaggaaat attataataa tattaggttt
    52981 acctcatcta aatgttgatt tagaataact gaaattaacg atagaagcag acaggtttta
    53041 atttggaggg gacatgttcc agaaattaaa gaatcttatt gatcggtatt cgtggttcgt
    53101 ttttataatg atgattcttg tgttatttct taactatatt tatccatttg atccttcttt
    53161 gagcggacta cagttggaat ggctgatcat gacgcaagtt tttcctggat taggtatcgt
    53221 atgtgccatg gttgctatta tttttaaaaa gtttaacctt tttgttttgg ccctaatttt
    53281 atattttgca ctttggttaa aacttttcct tgctttttct tttttcacct attttttagg
    53341 agtctgacta agtgccaatt tttaaaactc gtgaaagaaa atgtttgaca aaacttagtc
    53401 aagtagaaaa agttccttgc ttttaattga ctattagtgt acaataagat tctgtgagta
    53461 tacctcactt actcgctcca aaagtagtga gtcattagac caaaaggagg aaaatatcaa
    53521 tggctaaata cgaaattctt tatatcattc gtccaaacat tgaagaagaa gctaaaaacg
    53581 ctttggtagc acgctttgac tctatcttga ctgacaacgg tgcaactgtt gttgaatcaa
    53641 aagattggga aaaacgtcgt cttgcatacg aaatcaacga tttccgtgaa ggactttacc
    53701 acatcgttaa ccttgaagcg actgacgcag cagctcttaa cgagtttgac cgtctttcaa
    53761 aaatcaatgg tgacattctt cgtcacatga tcgttaaact tgacgcttaa ttccaactaa
    53821 gagggtagtt tatgattaat aatgtagtac tagttggtcg tatgaccaag gatgcagaac
    53881 ttcgttacac accaagtcaa gtagctgtgg ctaccttcac acttgctgtt aaccgtacct
    53941 ttaaaagcca aaatggtgaa cgcgaggcag atttcattaa ctgtgtgatc tggcgtcaac
    54001 cggctgaaaa tttagcgaac tgggctaaaa aaggtgcctt gatcggagtt acgggtcgta
    54061 ttcagacacg taactacgaa aaccaacaag gacaacgtgt ctatgtaaca gaagttgttg
    54121 cagataattt ccaaatgttg gaaagtcgtg ctacacgtga aggtggctca actggctcat
    54181 ttaatggtgg ttttaacaat aacacttcat catcaaacag ttactcagcg cctgcacaac
    54241 aaacgcctaa ctttggaaga gatgatagcc catttgggaa ctcaaacccg atggatatct
    54301 cagatgacga tcttccattc tagtcagaat ggattgaacg aatacgaaat tatttgagtt
    54361 cgggctaaaa atttagaact tagaatttag atcaactccc taggaaatca agatttcttg
    54421 ccagttttct aaaattcagt cgttttttaa gagcccttaa catcataatt tataaaggag
    54481 aaaatacatg gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag ttgacttcat
    54541 cgcagctaac aaaattgaat atgttgatta caaagatact gagcttctta gccgtttcgt
    54601 ttcagaacgt ggaaaaattc ttcctcgtcg tgtaacagga acttcagcta aaaaccaacg
    54661 taaaataaca acagcaatca aacgtgctcg cgttatggct cttatgcctt acgtaaacga
    54721 agactaataa acaaacagtc catttcggac tgttttttag ttgactagga ctagtctagg
    54781 cgtataggtg agttttttct aaaagagaga atgatagtaa acgaaaatcc ttgcgtagac
    54841 agcaaggatg aaatgattgt tatttgttaa caggtgacat agtgttttga atgttgtatt
    54901 tgcgttgtag gtaatagcgt aaagcaaggg aaacaccacc aataatgagc aaggcaagag
    54961 gaggcaactg tgggttaaga gaggttggta aaaaggcagt tgcagagtac aaggcaatcc
    55021 aaatcaacat ggctaatgat aaggctgcga tgattttgaa ccaacttgga cgaaggctct
    55081 tatcttttcc gagatgacgg taaataaagt aataagtagc gtacatggat gctcctccac
    55141 caaaaccaag tgccagtaag gaaatcaatc ctgtaactgt agcgtttgtg ttgaagaagg
    55201 tcatgatgcc atttaaaagg gcaacaattc cgatgaatag taaagaggta tctagccaca
    55261 tcaaccaagg attggtgttt ttgtcagttt ctgctgctct ttgactaggg tcttggctaa
    55321 aagaagctgc ccaagcagtc ggagtgccta atagatttcg agcggtgaca ccttttttct
    55381 ggttttctag aatagctgga atggcttctt cgagaatcag cttaatatcc tcatcagact
    55441 tgccgtcttg gattaatttg ttcgtagcgg tgtggataaa ttcttgattt tttttggtaa
    55501 gttcttgtaa ttccatggga atcccttctt tatatgggtt agttaaagta agtcaatggt
    55561 attagctagt tgtaatgaaa ctttggagct agccgtttga cacagagttt tgtcaggtct
    55621 taaacgtatt ctgcagcttg ctccactcta gaaccatttt tttctaataa agtaaatcac
    55681 aacaaaggaa ctaaggagca tagcaatcaa ggtaatatac caaaaagcat gttctaggcc
    55741 atttagtggt aaccagttgt tttggaaatt cataccatag gcggagaaaa tcacagttgg
    55801 tatatctaaa gccatggtca tcaaggccag tgttttcata atagtgttct ggttgttgtt
    55861 gataatagaa gcagtggttt cagtcatggc attcaagaca ttttcataaa tgccagccat
    55921 ctcaatggcc tgttgggttt caatcaaggt atcttctagc aaatcctcgt cctcaatgta
    55981 tttcttgaga gagcttgttg agctggataa tttcttgacg atgcgttcgt tgaatttcaa
    56041 ggaagccttt aagtagacaa tggatttttc aagttccatc atgtcgataa gttcttcatt
    56101 tcgagtagct gcttcaagct gagcttccaa acgttcgctt tggcgatcaa tggtcctcaa
    56161 ggcagtcaga aagagctcgg cgttgcgata tagaatctga aaaacaaaac gtgtcttcat
    56221 gaaggtatag aaatttttga cccggcggtt gtgaaaatga tcgaaaaggg tcatgtcatg
    56281 cagacaagtt gtgataacag cattttccgt tacaataatg cctaaaggca tagtaatata
    56341 gtaactttta ttgttacgtt cttcgtatat cgggacgtct acgataatta gggtataatc
    56401 atcttctacg gcaatacgtg aggtttcttc cacgtccaaa ggggcgcgca agtcagaaat
    56461 atcaatgtta aattgatcgg cgatcttcat agactcttct tgggaagggt taaccagttt
    56521 aatccaagct cctggctcga atgtttctat ttctttgaat tcaattgccg atgaaagaaa
    56581 catttgtttc atgacaagcc ctcctttttg atgattgact ggtagagatt gacatcaaac
    56641 cttgataata aagccttctc aaggattttc tgaaaaattc tcaatactta tctattatac
    56701 caaaattcgc aaagtttggg gcaataggtt atcagaaatt tttgttataa tataagaaag
    56761 ctcgatgagg agggtgcctt taggcacatt caagatgcaa aataaaataa taattcatgg
    56821 ggcaagagcc cacaatttaa aaaatattga cgtggaaatt ccacgagaca aattagttgt
    56881 cgtgacaggg ttatcagggt caggaaaatc tagtctagcc tttgatacta tttatgcgga
    56941 agggcaacgt cgttacgtag aaagtttatc agcttatgct agacagttct tgggtaatat
    57001 ggaaaaacca gatgtggatt ccattgacgg tcttagccct gctatttcca ttgatcaaaa
    57061 aactaccagt aagaaccccc gctcaacggt tggtacggtt acggaaatca atgattattt
    57121 acgtttacta tatgcgcgtg tgggcacacc ttactgtatt aatgggcatg gggccattac
    57181 agcatcttct gcagaacaaa ttgtagagca ggtcttagcc ctccctgaac ggacacgcat
    57241 gcagatttta gcgcctattg ttcgccggaa aaaaggtcaa cacaaaacca tttttgagaa
    57301 aattcaaaaa gatggttatg tccgtgtgcg ggttgacggg gatatttttg acgtgacaga
    57361 agtgccggag ctgtccaaaa gtaagatgca caacatcgag gtggttattg accgtctggt
    57421 taataaggat ggtattcgta gccgtttatt tgattcggtt gaagcagctt taaggctggg
    57481 agatggctac cttatgattg acactatgga tggcaatgaa ctgctctttt ctgagcatta
    57541 ttcctgtcct gtctgtgggt ttacggttcc tgaattagaa ccaagactct tctcttttaa
    57601 tgcgccgttc ggctcttgtc cgacctgtga tgggctaggc attaagttgg aagtggattt
    57661 ggacttggtt gttcctgacc caagtaagtc tttgagagag ggagctttgg cgccttggaa
    57721 tcctatttcc tccaattatt acccaaccat gcttgagcaa gctatggcaa gttttggggt
    57781 ggatatggat acaccttttg aggccttgac tgaggaagaa agagatttag tgctttatgg
    57841 ttcaggagat agagaatttc attttcacta tgtgaatgat tttggtggtg agcgtaacat
    57901 tgatattcct tttgaaggtg ttgtgactaa tgttaatcgt cgttatcacg aaactaatag
    57961 tgattatacg cgcaatgtga tgcgtggtta tatgaacgaa ttgacctgtg cgacttgtca
    58021 tggttaccgt ttgaatgacc aagccttgtg tgtgcatgtg ggtggcgaag aaggacctca
    58081 tattggtcaa atttcagaat tatcgattgc cgaccacttg cagttgttgg aagaattgga
    58141 actcacagaa aatgaaagta ccattgctaa accgattgtc aaagaaattc atgaccgcct
    58201 gaccttctta aataatgtgg gactgaatta tctgaccttg tcacgggctg ctgggacttt
    58261 atcaggtggt gaaagtcaac gaatcaggtt agcgacacaa attggttcta acttatcagg
    58321 ggtgatctat atcttggatg agccttctat tggattgcac caaagagaca atgaccgttt
    58381 gatcgaaagc ctgaaaaaaa tgcgtgattt gggtaatacc ttaattgtgg tagaacacga
    58441 tgaagacacc atgatgcagg cagactggct gattgatgtg gggcctgggg caggtgagtt
    58501 cggtggagaa attattgcct ctggaacgcc gaaacaagtg gctaagaata aaaaatccat
    58561 cacgggtcaa tatttgtctg gtaaaaaatt cattccagtg ccattagagc gtcgttctgg
    58621 taatgggcga ttcattgaaa taaaaggagc agcgcagaat aatcttcaaa gcctcgacgt
    58681 gagattccca ctgggtaaat ttattgcggt cacaggggta tcaggctcag ggaaatcaac
    58741 cttggttaat agtattttga aaaaggctgt cgcccaaaaa ttaaaccgta atgctgataa
    58801 gcctggtaaa tatcactcta tttctggtat tgaacatatt gaacgcttga ttgacattga
    58861 ccaaagtccg attggaagga cgccacggtc aaatccagcc acctatacgg gtgtctttga
    58921 tgatattcga gacttgtttg cccaaaccaa cgaagctaag attcgtggct acaaaaaagg
    58981 ccgtttctct tttaatgtca aaggtgggcg ttgtgaggct tgttcaggtg atgggattat
    59041 caaaatcgaa atgcactttt tgccagatgt ttatgtgcct tgtgaggttt gccacggcag
    59101 acggtataat tctgagacgc ttgaggtgca ttataaagaa aaaaatattg ctgaagtact
    59161 tgacatgact gtcgatgatg ccttggtatt tttctctgct atccctaaaa ttgcccgaaa
    59221 aattcaaacc attaaggatg ttggtttggg ttatgtgacc ttgggtcaac cagctactac
    59281 tctatctgga ggagaagcgc agcggatgaa attagctagt gaattgcaca aacgctcgac
    59341 aggtaagagc ttgtatatcc tagatgagcc aacgactggt ttacacacag atgatattgc
    59401 aaggctatta aaagttttgg aacgctttgt agacgatggt aatacggttc ttgtgattga
    59461 gcataatttg gacgttatca aatctgctga ccatattatt gacttaggac cagaaggtgg
    59521 tgtcggaggt ggtcagattg ttgccacggg gacaccagaa gaggtagctc aagttaaaga
    59581 aagctatact ggtcattatt tgaaagtaaa actacaacaa taggattagg agttcgtttg
    59641 agctcctttt taatctttta aatgctctca aatcatggta aacttaaagt agttttttca
    59701 tgctacaata ttctcaaaag ttaccaaagg agttcgcgat gtcaggattt ttagagcaac
    59761 gattaggtca ctgcctaagg cagatggcag agaaggggct agaggctctt ctagtcaccc
    59821 atttaaccaa tagttattac ttgacaggtt tttctggaac tgcagcaact gttttgataa
    59881 cggccaaacg tcgtgttttg atcacagatt cacgttatac cttgcttgct aaagctagtg
    59941 ttgagggatt tgatattatc gaaagccgca cgccgcttaa ggttgtggca gaattgttag
    60001 aggctgatca aatagattgc cttggttttg aggaccaggt atcgttttct ttttatcagg
    60061 ccatgcaagc agaactgtca ggaataacct tgcttgctca gtcaggtttt gtggagcatt
    60121 tacgttttat taaggatact tctgaaattg ataccattgc taaagcgtgc tcgatctcag
    60181 acaaagcatt tgaagatgct cttgatttta ttaaaccagg gacaaccact gaacgtgacc
    60241 tggctaattt tttagatttt cgtatgcgtc agtatggtgc cagcggcaca tcatttgata
    60301 tcattgtagc ttcaggctat cgctctgcca tgcctcatgg acgcgccagt gacaaggtta
    60361 tccagaataa agagagcttg accatggact ttgggtgtta ctacaatcac tatgttagtg
    60421 atatgacgag gaccattcat attggccaag ttactgatga agaacgtgag atttatgctc
    60481 ttgttcttgc tgctaataag gctttaattg ctaaagctat cgctggcatg acttatagtg
    60541 actttgacgg tattccgcgc caactcatca ctgaggcggg ttatggcagt cacttcacac
    60601 atggcattgg tcatggtatc gggcttgata tccacgagaa tccatttttt gggaaatctg
    60661 agcaacttct ccaagctgga atggtggtca cagacgagcc aggtatctat ttggataaca
    60721 aatatggtgt ccgtatcgaa gacgacttgg ttatcacaaa aactggttgt caagtcttga
    60781 ccttggcacc caaagaatta attgtattgt aaaagaatgg ttcaggaaag gattagggga
    60841 gaagcaatga caaatcgttt atcatggcaa gactatttta tggccaatgc agagctgatt
    60901 tccaagcgct ctacctgtga tcgcgccttt gtgggagctg ttttggtaaa ggataaccgc
    60961 attattgcca caggttacaa tggcggagtt tctgctacgg ataactgcaa cgaagcgggt
    61021 cattatatgg aagacggaca ttgtattcgc actgttcatg ctgaaatgaa tgctttgatt
    61081 caatgtgcga aagaaggaat ttcaacggac ggaactgaaa tttacgtgac tcattttcct
    61141 tgtattaact gcactaaggc gcttttgcag gcggggatta caaagattac ctataaagca
    61201 cattaccgtc cgcacccctt tgccattgaa ctgatggaga aaaaaggggt tgcctatgtg
    61261 caacatgatg tgcctcaaat tgttttagga ggcgataagg aacaatagaa agtgtaccta
    61321 aaaggacggt cataaaagat ttgagccaag gccacttttg tggtaaaatg aagtgataaa
    61381 tattttagta agaggtaata ataatgattg aagcaagtaa gcttaaagca ggtatgacat
    61441 ttgaagcaga aggaaaatta atccgtgtcc ttgaagctag ccaccacaaa ccaggtaaag
    61501 gaaacactat catgcgtatg aaactacgtg atgtgcgtac aggttctact tttgacacaa
    61561 cttaccgccc agatgaaaaa tttgagcaag ccatcattga aactgtccca gcacaatacc
    61621 tatacaaaat ggatgacact gcttacttca tgaacactga tacttatgat cagtacgaaa
    61681 ttccagttgc taacgttgag caagaattgc tttacattct tgaaaactca gacgtgaaaa
    61741 tccaatttta tggaagtgaa gtgattgggg taacggttcc aacaactgtt gaattgaccg
    61801 ttgcggaaac acaaccatct attaaaggag cgacggtgac gggttcaggg aaacctgcaa
    61861 ctcttgagac aggacttgtt gttaacgttc cagactttat cgaagctggc caaaaactaa
    61921 tcattaacac tgcagaaggt acttacgttt ctcgtgctta atcctttgtc aaaacagatt
    61981 agtctaaaaa agagaaagga aatgctatga caactgaata tatcggtgaa atcgtcattt
    62041 caccacgagt gcttgaggtt attacgggga ttgctacgac acaagttgag ggtgtccact
    62101 cactccataa caagaaaatg gcagatagct ttaacaaagc aagtcttggt aaaggggttt
    62161 atctccagac agaagaagat ggaagtgtta cagcagatat ttatgtttac ttgcaatatg
    62221 gagttaaggt cccgactgta tctatgaata ttcaaaaaac agtcaaatct gctgtgtacg
    62281 atatggcaga agtgcctatt tctgcagtta atatccatgt tgaaggtatt gttgcggaaa
    62341 agacaccaaa accagatttg aagtcacttt ttgatgagga tttcttggat gactaacagc
    62401 tttcaaaatt caagaagaga tttgcgtgaa cgtgcctttc aggctttatt taacatagag
    62461 atgggagctg agttattggc agcttctcag tttgcctatg gttatgataa agtaacaggg
    62521 gaggacgctc aagtattgga gctgccgatt tttttattaa gtcttgtgac gggtgtcaat
    62581 aatcataaag aagagttgga taacttgata tcaactcatt tgaaaaaagg ttggtcgtta
    62641 gaacgcttga cactaacaga caaaacgtta ttacgactag gtctttttga aatcaagtat
    62701 tttgacgaaa caccagaccg tgttgcacta aacgaaatca ttgaagtagc taaaaaatat
    62761 tctgatgaaa cctctgctaa atttattaat ggcttactta gccaatatgt ctcggaagct
    62821 ccttcagcaa ataaatcata ataagtcgga gcaatcttag gattgtatcc gattttttca
    62881 atttatgtac gaatattaaa agacaaacaa gcatactctc gcatctagaa agagtatgct
    62941 tgtttgtctt ttagagtaat tagtgattgg ttatgttttg tttaaatact tgctcctgga
    63001 agtagcgtaa tcggtaaaat atagtcttta cttgtttttt cttttttaat ttttttgatg
    63061 agtatttcga cactcaattt agcaatctca tcaataggtt gacgaatggt cgctaattga
    63121 ggaacatatt gctggataaa tgtcgttcca tcataaccta tgactttcat atcctctgga
    63181 atagtaatgt gaagttgttt ggctactttc ataatgagga tagcagttaa atcatcagaa
    63241 acgaaaaggc catcaggttt tcgggttgcc aaaatggatt taatttccat ttcgcgtcta
    63301 acaggagata ggttatttgg taatttgatg atttctgcac ttcgtttgag ctggtagtta
    63361 aaccctagct ggcgcaaccc tgtgggcgaa tcagaattgt cattacctgt aatcatgaca
    63421 atgttttgac aaccgtgttt ttgcaaagtt tgtgcggcta atttaccacc ttcaaaatta
    63481 tctgaagaaa taaccggaat atttggcgcc agattacggt caaaagctac aataggagct
    63541 tcgacacgct cataatcctc aattcccaaa ttatgactgg aagaaataat gccgtccact
    63601 tgattggccg caagcatttc taagtattcg cgttctttga cgggattatg ttcactattg
    63661 caaataatag ttttgtagcc ctgtttaaac aattcaattt ccaaatgttc aattaattca
    63721 gcgtaaaaga tattgctaat gttggggaag ataagcccaa tgagttgggt tgatttacct
    63781 tgcaaacttc tagcgagatt gttaggcttg tagcccaatt cacgcatggc cttattcacc
    63841 ttattcactg ttttttggga aaggtagcct tttttgttga ttactcgcga aacagttgtt
    63901 ggactgacac ccgccaaggc tgccacgtct gttaattttg cgaccacttg cctaatacct
    63961 catttcataa taatgtccaa aagcttgtcc ttttactact tggatacctg tttgtccttg
    64021 ggttgggaaa acacgactag ttaggacttt ttgcccttgg ttaataaaga tttcaagaat
    64081 ggaattgtcc acatagacat taagtgtaac atggccttgt gggatttggc aagagcgcac
    64141 cgtaccatag tcttgggcat attgaacccc tgcccgactt cggtcaatgc ttaactgtcc
    64201 ttttgttgta tccactttca atcttaggcc attccctttt tggtcagtaa ataggagcag
    64261 gtcaagcttt ttttggcctg gaatcgtcaa ttccaattca taacagttag aactgtctat
    64321 tttattatga aataattctg ctggccctcg aagattttgt agggctgaaa caggtgtttg
    64381 atagagaatt ccgtctttaa tccttaattc tttcactaaa ctaagagctc cttgatagtc
    64441 ataacgatct gtcggataat caatatctgg taacccaatc caagacacgg ctagaaccct
    64501 gccatctgga ctactaaagg cttgagtggc ataagcttca aaaccaaagt caagattttg
    64561 aaggaccccc ccacccagca attggccagt ttctggattg aagctttcaa aaattttata
    64621 ggtattgggg tagatatttt gataatctaa atcagcttta gccagtcctt gtgggctgaa
    64681 aatcaaaaca ggcttgtcat cgacaaacac aaggttgggg cattcaatca tgtattccgt
    64741 accagaatcg tcaaagtcca aatcggctat aaatcgccag ttgtccacat gattgtccac
    64801 agctttgtaa agtttgattt ttcctttgcc atctaaacct tgggcgccaa taatagcata
    64861 gaattgacct tgataagaaa aaagctgagg atcccgaaaa tgttctgtaa catcatcggg
    64921 ctgttcaatc aaaacctgtg gtattttgga aatatttcct tgtttatcca tccatgcgcc
    64981 aacctgtaat ggtgttctga cccaattggc atcgcgaaca ttaccagtgt aaaagaggaa
    65041 gagcttgtca tcaatagcat aggcagaacc tgagtaagcc ccatgactat cgtgagcgtg
    65101 gtctggcaga aggcggctcc ttgtttccgt aaaatggacg aggtctgtgg atgtcatgtg
    65161 tacccattgt ttcagaccat gcgcagcccc ataaggccag ttttgataaa aaagatggta
    65221 gtgaccgttg aaataagaaa acccattggg gtcattgagt aatcctgtct taggttcgac
    65281 atgaaattgg ctgtgccatg gggattgggc cattttttca gtaatagctt ggtagtcttt
    65341 tgagctccac tctttgtaag ggcggtagcg aatagcttgt ggtagatcca tcaaaatctc
    65401 cttgttttat agtcgtcttc aagaatatac taaacgtttt ctgtttaaaa atcaagaatt
    65461 taaatcatat aaaataaaaa tatgttaaac gcttgacata aaaaatatta gtgataaaat
    65521 gatagtcaag aagtgaagcg gattcactag cgttggtcat gcacattctt agccacaaag
    65581 ctggcagaat ggatgaggga ctaacaccaa atgaaaaagg agacttttag gcatggataa
    65641 tcgtcagatt gcagctgaag tgattgaggc tttaggtggc cgagaaaatg tgagaagtgt
    65701 tgcccactgt gcaactcgcc ttcgcgtgat ggtttatgat gaaggaaaga ttgataagga
    65761 aaaagcagaa gctattgaca aggttaaagg agctttcttt aactctggtc aatatcaaat
    65821 gatttttgga actggtaccg tcaataacat ttatgacgaa gtcgttgctc ttggtttacc
    65881 aacatcatca accagtgagc aaaaagcaga agcaggcaaa caaggcaata tcttccaacg
    65941 ggcgattcgt acgtttgggg atgtctttgt tcccattatt ccagctattg tagcaacggg
    66001 tctctttatg ggggttcgtg gtttggtgac ccagccagct attatggatt tatttggggt
    66061 gcatgagtac ggggaaaatt ttctcatgta cactcgtatt ctaacggata cagcctttgt
    66121 ctacttgcca gctttggtgg cttggtcagc ctttagggtc tttgggggta atcctattat
    66181 cggtattgtt ttaggcttga tgttggtgtc caatgaattg ccaaacgcct gggtagttgc
    66241 ctctggtgga gatgttaagc cgctaacctt ctttggattt gttcctgttg ttggttatca
    66301 aggtaccgtt ttacccgcct tctttgttgg tctggtagga gctaagttgg agaaatggtt
    66361 gcacaaaaag gttccagaag ctttagactt attggtcaca ccgtttttaa cgtttgctat
    66421 tatgagtacc ttgggactat ttgtgattgg accagttttc cattctcttg aaaaccttgt
    66481 tctggctggg acacaggccg tcttgcattt gccgtttggc attgctggtc ttattgttgg
    66541 tggtatccaa cagttgatcg tcgttactgg tattcaccat atctttaact tcctagaagc
    66601 gcagctgatt gccaataccg gaaaagatcc tttcaatgct tacctaacag cagcaacagc
    66661 tgctcaagct ggagctacct tagctgttgc tgttaaaacc aaatcaacaa aactaaaagg
    66721 tctggccttt ccatcaacct tgtcagctct tttagggatt actgaaccag ctatttttgg
    66781 ggtcaacctc cgttatccaa aagtctttgt ttcaggtctt attggtggtg ccttaggtgg
    66841 ttgggtcgct gggctctttg gcattgcagg aactggtttt gggattacgg ttttaccagg
    66901 aactctcctt tacttgaatg gccaattatt acaatacctt gtgactatgc ttgtcggtct
    66961 tggggtagcc tttgcaattg cttatacttg gggttatcaa gatagagaaa cccttccgtt
    67021 accagctgtc gaagttgatc aaacggctga tcagccagcc ttagcagagg aaactttata
    67081 tagtcctttg aatggaacag ttgtagattt agcagctgtt tcagaccctg ttttttcatc
    67141 aggtgctatg ggtcaaggct tagcaattaa gccagaagat aataccctat actcaccagt
    67201 tgatggtaaa gttgaaattg tctttgaaac aggtcatgcc tatgctataa cgtcaagtca
    67261 aggagcagaa gtgttacttc atattggtat tgataccgtg tcgatggcag gagatggctt
    67321 tgaatctctt gtagcagtag gtcaggcagt taaaaaaggt gatcttcttg gacactttga
    67381 tcctagcaag attgcagaag ctggactaga tgacaccacc atgatgattg tgaccaatag
    67441 cgctgactat caaagcgtgg acattcttgc tcaaggacat gttttgattg gtgatcaagt
    67501 ggcacttatc aaataaggac aaaagagcta actaagcagc tcttttgtcc tgccatgaat
    67561 ggcaggttgg caaaaaaatg agaaaagcct aaaaacctta aatttgtgtt attttaccta
    67621 tactttgtac cttgtttttt ttaataaagt gttgttatac ttaaggcgaa ctataggaat
    67681 gcgcttacat agatggtata tcaactggga agccatgact tagtaccaaa aataaggagt
    67741 gtccaaatgg ataaacattt gttggtaaaa agaacactag ggtgtgtttg tgctgcaacg
    67801 ttgatgggag ctgccttagc gacccaccat gattcactca atactgtaaa agcggaggag
    67861 aagactgttc aggttcagaa agaattatct tctatagata gcttgcatta tctgtcagag
    67921 aatagcaaaa aagaatttaa agaagaactc tcaaaagcgg ggcaagaatc tcaaaaggtc
    67981 aaagagatat tagcaaaagc tcagcaggca gataaacaag ctcaagaact tgccaaaatg
    68041 aaaattcctg agaaaatacc gatgaaaccg ttacatggtc ctctctacgg tggttacttt
    68101 agaacttggc atgacaaaac atcagatcca acagaaaaag acaaagttaa ctcgatggga
    68161 gagcttccta aagaagtaga tctagccttt attttccacg attggacaaa agattatagc
    68221 cttttttgga aagaattggc caccaaacat gtgccaaagt taaacaagca agggacacgt
    68281 gtcattcgta ccattccatg gcgtttccta gctggaggtg ataacagtgg tattgcagaa
    68341 gataccagta aatacccaaa tacaccagag ggaaataaag ctttagccaa agctattgtt
    68401 gatgaatatg tttataagta caaccttgat ggcttagatg tggatgttga acatgatagt
    68461 attccaaaag taaatggaga agctagtgac gaaaatctca agcgatctat tgatgttttt
    68521 gaagaaattg ggaaattaat tggaccaaaa ggtgttgata aatcgcggtt atttattatg
    68581 gatagcacct atatggctga taaaaaccca ttgattgagc gaggagcttc ttatattaat
    68641 ttattactgg tacaggtcta tggttcacaa ggagagaaag gtgtctttca aaatgatacc
    68701 aaattagtca ccgatacccc tgaagaacga tggcaaggtt atagcaagta tattcgtcct
    68761 gaacaataca tgattggttt ttctttctat gaggaaaatg ctcaagaagg gaatctttgg
    68821 tatgatatta attctcgcaa ggacgaggac acggcaaatg gaattaacac tgacataact
    68881 ggaacgcgtg ccgaacggta tgcaaggtgg caacctaaga caggtggggc taagggaggt
    68941 atcttctcct acgctattga ccgagatggt gtagctcatc aacctaaaaa atatgctaaa
    69001 cagaaagagt ttaaggacgc aactgataac atcttccact cagattatag tgtctccaag
    69061 gcattaaaga cagttatgct aaaagataag tcgtatgatc tgattgatga gaaagatttc
    69121 ccagataagg ctttgcgaga agctgtgatg gcgcaggttg gaaccagaaa aggtgatttg
    69181 gaacgtttca atggcacatt acgattggat aatccagcga ttcaaagttt agaaggtcta
    69241 aataaattta aaaaattagc tcaattagac ttgattggct tatctcgcat tacaaagctc
    69301 gaccaatctg ttttacccgc taatatgaag ccaggcaaag ataccttgga aacagttctt
    69361 gaaacctata aaaaggataa caaagaagaa cctgctacta tcccaccagt atctttgaag
    69421 gtttctggtt taactggtct gaaagaatta gatttgtcag gttttgaccg tgaaaccttg
    69481 gctggtcttg atgccgctac tctaacgtct ttagaaaaag ttgatatttc tggcaacaaa
    69541 cttgatttgg ctccaggaac agaaaatcga caaatttttg atactatgct atcaactgtc
    69601 agcaatcatg ttggaagcaa taaacaaaca gtgaaatttg acaagcaaaa accaactggg
    69661 cattacccag atacctatgg gaaaactagt ctgcgcttac cagtggcaaa tgaaaaagtt
    69721 gatttgcaaa gccagctttt gtttgggact gtgacgaatc aaggaaccct aatcaatagc
    69781 gaagcagact ataaggctta ccaaaatcag cagattgctg gacgtagctt tgttgattca
    69841 aactatcatt acaataactt taaagtttct tatgagaact ataccgttaa agtaactgat
    69901 tccacattgg gaaccactac tgacaaaacg ctagcaactg ataaagaaga gacctataag
    69961 gttgacttct ttagcccagc agataagaca aaagctgttc atactgctaa agtgattgtt
    70021 ggtgacgaaa aaaccatgat ggttaatttg gcagaaggcg caacagttat tggaggaagt
    70081 gctgataagg aaatgtctag aaacgtattt gatggttctt taggaggaga ccgatctaat
    70141 ctactaggca tgtcaggacc aaaatctaca attattttta atttaaaaga atctggaata
    70201 gtaaaacact ggagattttt taatgataga gcacggtcac ctcagaatcc ggccgaagac
    70261 atccaagaaa ttaaactcca agtctttgac tcagaaaaat acgatattga aacactatta
    70321 aagacgccta atcaatttga taaagacgat tactggatta cggttgatag ttataaatca
    70381 aaatccgaaa ctgttaataa ttatgatcaa gttttgaaaa tgaattcagc caaatactgg
    70441 agagtaaccg tagatactaa gggaggaaat tatagttggc catcactccc tgaactccaa
    70501 attttaggtt atccgttacc taacgccgac actatcatga aaacagtaac tattgctaaa
    70561 ggtctatctc aacaaaaaga taagttttct caaaagatgc ttgatgagtt aaaaataaaa
    70621 gagatggctt tagaaacttc tttgaacagt aagatttttg atgtaactgc tattaatgct
    70681 aatgctggag ttttgaaaga ttgtattgaa aaaaggcagc tgctaaaaaa ataaacaaag
    70741 caactttctt agatagcaac attcagatta aattaacaaa atgtgactat gataaaggtt
    70801 tgctggaatt gattaaccaa aagactaaaa atctgagatg aatagtccca gatttttagt
    70861 cttttatagg ttttgatgac ataaagctaa ataatcgtta gactaccaga aagtggcgct
    70921 tgtccgtgag acatggctgt cttgataaga gcctgtgtca tcataaagat aaaaaagaac
    70981 aagaaaaagg agaaaacatg ggaaaattat atggaagcat tgaagctggt gggacaaagt
    71041 ttgtctgtgc cgtgggtgat gaggagttta cagtggtgga taaaacacaa tttccgacca
    71101 ccacaccaga agaaaccatc gcgcaaacca tcgcatattt taaaaccttt gaggccgatt
    71161 tggctggaat ggcgattggt tcttttggac caattgatat tgatccgtcg tcagagactt
    71221 acggttacat cacaaccact cctaagtcag gctgggctaa tgtggatttg ttaggacaac
    71281 tttcggctgc ttttaagatt ccttttgatg tgacaacaga tgttaatagc tctgcttatg
    71341 gtgaggtgct tgctcgtcct ggtgtggaaa gtttggtcta ttacaccata ggtactggta
    71401 ttggggcggg agctattcaa catggccact ttattggggg attaggtcat acagaagcgg
    71461 gtcataccta tgtcatgcct catcctgatg atatggccaa gggattttta ggtgtttgcc
    71521 cttttcataa agggtgtctg gaagggatgg cagcaggtcc aagtattgag gccagaacgg
    71581 gagtgagagg tgaacgactt gatcaggaag ctgatgtttg ggacattcaa gccttctaca
    71641 ttgcccaagc agcgctgcaa gcaactatgc tttaccgtcc tcaagtgatt gtttttggcg
    71701 gaggtgtcat ggcgcaagaa catatggtgt tgcgcgtgca tgataaattc actacccttt
    71761 taagcggtta tttgccagtc cctgatttga cagactacat tgttactcca gctgttgctg
    71821 ataatggctc cgctactctg ggaaattttg ctttggccaa gttggctgca caaggaaaat
    71881 agggtctgtt tttgcctgct tgtctagtaa aagaaagcgc agtcagctag aacatgctat
    71941 aataaacaga gattaacatc agaagcgagg aatattatgt cagaaccatt atttctaaaa
    72001 tcaaccatgc acgacaggat ttggggtggc accaagttga gagatgtctt tgcttacaac
    72061 atcccaagtg acaccacagg tgagtattgg gctatttctg ctcatcctaa tggtgtttcg
    72121 acagttacta atggacgtta tcaaggacaa cctttaaaca cattatatgc gcaagagccg
    72181 gccttgtttg ggaatccaaa ggaagaagtt tttccactgt taactaagat tttagatgct
    72241 aatgactggc taagtgtcca agttcatcct gatgatgctt atggacgtga acatgaagga
    72301 gaattaggca agacagaatg ctggtatatt atttctgccg aagagggttc tgaaattgta
    72361 tacggccatc aggccaagtc caaagaagac cttcgtgcca tgattgaagc aggtgcttgg
    72421 gatgatttgc tgactcgtgt cccagtcaaa gcaggcgatt ttttctatgt tccaagtggc
    72481 accatgcatg cgatcggcaa gggaattctt attttagaaa cccagcagtc atctgatacc
    72541 acttatcggg tttatgattt tgaccgtaag gacgttaatg gtaatcttcg tgaccttcat
    72601 attgaaaagt ctattgatgt cttaacgatt ggtaagccag aaaatagcgt gccagccact
    72661 atggttttgg ataatatggt agcaacaact ttagtctcaa cgccattttt cactgtttac
    72721 aaatgggtga ctagtcaaat ggttgacatg aaacaagctg cgccttatct tttagtgagt
    72781 gttttaaaag gtcaaggaaa actctatgtg gaccagaagg cttatgagct agaaaaaggc
    72841 atgcacttta tcttgcctaa cgatgttaaa tcgtggtcat ttgatggtca attagaaatg
    72901 attgtgagtc accccaatca actcgtttaa taccatggta tcaatatgag aaaaaaggat
    72961 aaaattatga ctctctgttt ctctgataac ttta
//
LOCUS       DAUGUF010000004        67806 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUGUF010000004 DAUGUF010000000
VERSION     DAUGUF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67806
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.004"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            633..812
                     /locus_tag="VIB71_000233"
     CDS             633..812
                     /locus_tag="VIB71_000233"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8821994.1"
                     /translation="MTKLERPQEENEYLRTEVAYLKKPRELRLKEASLQRRRQKTIIK
                     NGQRRALIRFSFKDG"
     gene            complement(961..1884)
                     /locus_tag="VIB71_000234"
     CDS             complement(961..1884)
                     /locus_tag="VIB71_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8821995.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1877..2947)
                     /locus_tag="VIB71_000235"
     CDS             complement(1877..2947)
                     /locus_tag="VIB71_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8821996.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2956..3882)
                     /locus_tag="VIB71_000236"
     CDS             complement(2956..3882)
                     /locus_tag="VIB71_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8821997.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3882..5384)
                     /locus_tag="VIB71_000237"
     CDS             complement(3882..5384)
                     /locus_tag="VIB71_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8821998.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYKKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5449..7419)
                     /locus_tag="VIB71_000238"
     CDS             complement(5449..7419)
                     /locus_tag="VIB71_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8821999.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYENAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            7750..8982
                     /locus_tag="VIB71_000239"
     CDS             7750..8982
                     /locus_tag="VIB71_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8822000.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFAGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            9150..10331
                     /locus_tag="VIB71_000240"
     CDS             9150..10331
                     /locus_tag="VIB71_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8822001.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYTFLRKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(10483..11901)
                     /gene="sufB"
                     /locus_tag="VIB71_000241"
     CDS             complement(10483..11901)
                     /gene="sufB"
                     /locus_tag="VIB71_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEQ8822002.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(11894..12373)
                     /locus_tag="VIB71_000242"
     CDS             complement(11894..12373)
                     /locus_tag="VIB71_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEQ8822003.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(12360..13586)
                     /locus_tag="VIB71_000243"
     CDS             complement(12360..13586)
                     /locus_tag="VIB71_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8822004.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMINFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(13617..14879)
                     /gene="sufD"
                     /locus_tag="VIB71_000244"
     CDS             complement(13617..14879)
                     /gene="sufD"
                     /locus_tag="VIB71_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEQ8822005.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKISANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLNQETAERLVIRGF
                     LGAVIAEIPIPSVHQEIIKVLDEKLLNR"
     gene            complement(14974..15744)
                     /gene="sufC"
                     /locus_tag="VIB71_000245"
     CDS             complement(14974..15744)
                     /gene="sufC"
                     /locus_tag="VIB71_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEQ8822006.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(15866..17035)
                     /locus_tag="VIB71_000246"
     CDS             complement(15866..17035)
                     /locus_tag="VIB71_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEQ8822007.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(17042..17803)
                     /gene="mecA"
                     /locus_tag="VIB71_000247"
     CDS             complement(17042..17803)
                     /gene="mecA"
                     /locus_tag="VIB71_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEQ8822008.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(17949..18788)
                     /locus_tag="VIB71_000248"
     CDS             complement(17949..18788)
                     /locus_tag="VIB71_000248"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEQ8822009.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTHYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(18854..20779)
                     /locus_tag="VIB71_000249"
     CDS             complement(18854..20779)
                     /locus_tag="VIB71_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEQ8822010.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRTGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGKEPV
                     DVSTSKKNKIVALETKISRRRTLLQLLFGKVIPLVEVGFLLSQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASATITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSHSVQGLGCLLVVLNSSLLIYLTMKGSGLALIYLALMVLMMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            20977..22545
                     /locus_tag="VIB71_000250"
     CDS             20977..22545
                     /locus_tag="VIB71_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8822011.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYAEAKSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRHIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            22538..23278
                     /locus_tag="VIB71_000251"
     CDS             22538..23278
                     /locus_tag="VIB71_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822012.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     IAEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            23420..23536
                     /locus_tag="VIB71_000252"
     CDS             23420..23536
                     /locus_tag="VIB71_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEQ8822013.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(23762..24772)
                     /gene="gap"
                     /locus_tag="VIB71_000253"
     CDS             complement(23762..24772)
                     /gene="gap"
                     /locus_tag="VIB71_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEQ8822014.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(25120..27198)
                     /gene="fusA"
                     /locus_tag="VIB71_000254"
     CDS             complement(25120..27198)
                     /gene="fusA"
                     /locus_tag="VIB71_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEQ8822015.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(27565..28035)
                     /gene="rpsG"
                     /locus_tag="VIB71_000255"
     CDS             complement(27565..28035)
                     /gene="rpsG"
                     /locus_tag="VIB71_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEQ8822016.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(28056..28469)
                     /gene="rpsL"
                     /locus_tag="VIB71_000256"
     CDS             complement(28056..28469)
                     /gene="rpsL"
                     /locus_tag="VIB71_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEQ8822017.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(28677..31298)
                     /locus_tag="VIB71_000257"
     CDS             complement(28677..31298)
                     /locus_tag="VIB71_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEQ8822018.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKHNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLKDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPSLTGVKPLSYSKVETTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESR"
     gene            complement(31289..32128)
                     /gene="purR"
                     /locus_tag="VIB71_000258"
     CDS             complement(31289..32128)
                     /gene="purR"
                     /locus_tag="VIB71_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEQ8822019.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSENDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(32395..33333)
                     /locus_tag="VIB71_000259"
     CDS             complement(32395..33333)
                     /locus_tag="VIB71_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEQ8822020.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVEEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(33323..34594)
                     /locus_tag="VIB71_000260"
     CDS             complement(33323..34594)
                     /locus_tag="VIB71_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEQ8822021.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEKINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            complement(34596..35228)
                     /locus_tag="VIB71_000261"
     CDS             complement(34596..35228)
                     /locus_tag="VIB71_000261"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEQ8822022.1"
                     /translation="MTKVALFSGGDLSYFTREFDYFVGIDSGSLFLLENGLPLNMAVG
                     DFDSVSQEAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(35221..35883)
                     /locus_tag="VIB71_000262"
     CDS             complement(35221..35883)
                     /locus_tag="VIB71_000262"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEQ8822023.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGTL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     HD"
     gene            complement(35893..36765)
                     /gene="rsgA"
                     /locus_tag="VIB71_000263"
     CDS             complement(35893..36765)
                     /gene="rsgA"
                     /locus_tag="VIB71_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEQ8822024.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(37189..38061)
                     /gene="rsmA"
                     /locus_tag="VIB71_000264"
     CDS             complement(37189..38061)
                     /gene="rsmA"
                     /locus_tag="VIB71_000264"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEQ8822025.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(38175..38765)
                     /gene="rnmV"
                     /locus_tag="VIB71_000265"
     CDS             complement(38175..38765)
                     /gene="rnmV"
                     /locus_tag="VIB71_000265"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEQ8822026.1"
                     /translation="MQRGYLSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(38737..39528)
                     /locus_tag="VIB71_000266"
     CDS             complement(38737..39528)
                     /locus_tag="VIB71_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEQ8822027.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALALADQYPNVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKETTANAKRVFKLD"
     gene            39813..40643
                     /locus_tag="VIB71_000267"
     CDS             39813..40643
                     /locus_tag="VIB71_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEQ8822028.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            complement(40754..41692)
                     /locus_tag="VIB71_000268"
     CDS             complement(40754..41692)
                     /locus_tag="VIB71_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8822029.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITPEKIENNLASS"
     gene            complement(41714..42628)
                     /locus_tag="VIB71_000269"
     CDS             complement(41714..42628)
                     /locus_tag="VIB71_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEQ8822030.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIVDKDLEKAKTLQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(42640..43302)
                     /locus_tag="VIB71_000270"
     CDS             complement(42640..43302)
                     /locus_tag="VIB71_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEQ8822031.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLFTTYSSYFKHYFKRGMRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVRKELSLSTLFKRSFLLAGLFFP
                     WSFAFLALICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(43459..44289)
                     /locus_tag="VIB71_000271"
     CDS             complement(43459..44289)
                     /locus_tag="VIB71_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8822032.1"
                     /translation="MTKKKLTASDVLTTVILCILTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQWILFSIFIAAMALPKQVVLVPLVRIVNFIGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(44302..45189)
                     /locus_tag="VIB71_000272"
     CDS             complement(44302..45189)
                     /locus_tag="VIB71_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8822033.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLMNTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIAILLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(45293..46612)
                     /locus_tag="VIB71_000273"
     CDS             complement(45293..46612)
                     /locus_tag="VIB71_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8822034.1"
                     /translation="MNMKKLASLVMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTKEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAISNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(46661..47365)
                     /locus_tag="VIB71_000274"
     CDS             complement(46661..47365)
                     /locus_tag="VIB71_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEQ8822035.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            complement(47639..47773)
                     /gene="rpmH"
                     /locus_tag="VIB71_000275"
     CDS             complement(47639..47773)
                     /gene="rpmH"
                     /locus_tag="VIB71_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEQ8822036.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(48087..49001)
                     /locus_tag="VIB71_000276"
     CDS             complement(48087..49001)
                     /locus_tag="VIB71_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEQ8822037.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKNAPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTERKVQQPSIPVEESEVPQDPGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(49013..49840)
                     /locus_tag="VIB71_000277"
     CDS             complement(49013..49840)
                     /locus_tag="VIB71_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8822038.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(49806..50165)
                     /gene="rnpA"
                     /locus_tag="VIB71_000278"
     CDS             complement(49806..50165)
                     /gene="rnpA"
                     /locus_tag="VIB71_000278"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEQ8822039.1"
                     /translation="MKKTYRVKCEKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGYQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            complement(50705..51445)
                     /locus_tag="VIB71_000279"
     CDS             complement(50705..51445)
                     /locus_tag="VIB71_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8822040.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(51449..52732)
                     /locus_tag="VIB71_000280"
     CDS             complement(51449..52732)
                     /locus_tag="VIB71_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8822041.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSVIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            complement(52729..54075)
                     /locus_tag="VIB71_000281"
     CDS             complement(52729..54075)
                     /locus_tag="VIB71_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8822042.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLETYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            complement(54470..55915)
                     /locus_tag="VIB71_000282"
     CDS             complement(54470..55915)
                     /locus_tag="VIB71_000282"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEQ8822043.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            complement(56097..56807)
                     /locus_tag="VIB71_000283"
     CDS             complement(56097..56807)
                     /locus_tag="VIB71_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEQ8822044.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLGHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIIALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            complement(56938..57435)
                     /locus_tag="VIB71_000284"
     CDS             complement(56938..57435)
                     /locus_tag="VIB71_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEQ8822045.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGMDVSGQDFLPFQDVEDSVREDMTKIRASSLISDDVVINGAVYDVDTGKM
                     TQVME"
     gene            complement(57624..58985)
                     /gene="radA"
                     /locus_tag="VIB71_000285"
     CDS             complement(57624..58985)
                     /gene="radA"
                     /locus_tag="VIB71_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEQ8822046.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            complement(59066..59512)
                     /locus_tag="VIB71_000286"
     CDS             complement(59066..59512)
                     /locus_tag="VIB71_000286"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEQ8822047.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            complement(59622..60389)
                     /locus_tag="VIB71_000287"
     CDS             complement(59622..60389)
                     /locus_tag="VIB71_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEQ8822048.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            complement(60507..62291)
                     /locus_tag="VIB71_000288"
     CDS             complement(60507..62291)
                     /locus_tag="VIB71_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822049.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTMTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            complement(62294..64000)
                     /locus_tag="VIB71_000289"
     CDS             complement(62294..64000)
                     /locus_tag="VIB71_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822050.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLVQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            complement(63993..64442)
                     /locus_tag="VIB71_000290"
     CDS             complement(63993..64442)
                     /locus_tag="VIB71_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8822051.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            64740..65756
                     /locus_tag="VIB71_000291"
     CDS             64740..65756
                     /locus_tag="VIB71_000291"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8822052.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            65789..66688
                     /gene="galU"
                     /locus_tag="VIB71_000292"
     CDS             65789..66688
                     /gene="galU"
                     /locus_tag="VIB71_000292"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEQ8822053.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(66787..67458)
                     /locus_tag="VIB71_000293"
     CDS             complement(66787..67458)
                     /locus_tag="VIB71_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEQ8822054.1"
                     /translation="MTQLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
BASE COUNT        20595 a        14330 c        12296 g        20585 t
ORIGIN      
        1 tgtcgctgac agatttattt ctcgtttctt gacgggtaat atgtctccat atcaccctca
       61 cgtttggttc gtcttattca gttctcaaag gtcttaacgt ctcctaagaa acaacttctt
      121 tattctatca ggtttctcat agcctgtcaa ctactttttc atcttttttc aataagtgtg
      181 ttacaggaac ctctctgaca gctttattag tatacgatat ctttactgtc attgtcaact
      241 ctttttttac tttttttgta cttttttatt tgcccgcgtt gtaaaatgaa gtgcaacaaa
      301 aaagaggaaa agctttgaac tacaccccaa acgttagaca aaaaaatcta acgttcgggg
      361 tattttttat gaaattaagt gatgaaggta cgaaatagac atcgttaaga aagaaaaaaa
      421 tacctactat ccaccagaga taaagcaaga aataatagat aacgttttga tagaaggccc
      481 gccacaatac caagtatcac ttgtttatgg cttgttacat gcaggaactc tcccaagttg
      541 aatagcacaa tataagaaaa acagttatac tgttgagaaa acaagagcaa gaccatcaca
      601 aacaggacgt aaaccaaaag aaacctgaag aaatgactaa attagagcgg cctcaagaag
      661 aaaatgaata tctcagaact gaggttgctt acttaaaaaa accgagggaa ctccgtttga
      721 aagaagcatc tctgcaaaga agaagacaaa aaaccattat aaagaatgga caaagacgag
      781 ctctgattag attttctttt aaggacggct aaattgactc gttctaccta ctattatcat
      841 cgattattgc aacaataaac gtatcaaaat aaaacgaaaa ggacttagtc ctctacaaca
      901 cagaactaaa tcctttactt caaatagagt agccaacttt tggggctcag tgcatctctt
      961 ttacaattct ttttgatatt tttcaatttc tgcttggttt gcccaaacaa agtgatttgg
     1021 tttgatttca accattgatg gcttatctaa tgtataatca tgctggtctg gatgatagac
     1081 aacaagttct ttttgacgct ctaaaattgg atctgggata ggcacggctg ataacaaaga
     1141 ttgggtgtag ggatgaattg ggttattaaa cagttcttct gtttctgcaa cttctacaat
     1201 aaccccttta tggataaccg caatacgatc tgaaataaag cgaacgactg aaagatcatg
     1261 ggcaatgaag agataagtca aacctttttc ggcttgcatt cttttaagaa gattcaagac
     1321 ctgtgcgcga acggaaacgt ccaaagctga aatcggttca tcagcaataa cgaattcagg
     1381 gttcattact agggctctag cgataccgat tcgctgacgt tgacctcctg aaaattcatg
     1441 agggtagcgc gtcaaatgct ctgatagcaa accaacttcg gccatcatgt tcttaatttt
     1501 ttctttacgt tcttcctctg ttttaaacag attaaagtta taaaggcctt ctgaaatgat
     1561 gtagtcaacg gttgcccgtt cattcaaact agcagcggga tcttggaaaa tcatttgaat
     1621 tttacgaatg agctcattgg cttctgattt tgattttctg ccattaatta ctttcccatc
     1681 gtataaaatt tgacctgaac tagtatcgtt caaaccaata atagcacgac caattgttgt
     1741 tttaccactc ccagactctc caactaaaga aaaggtttct ccttttttaa taaagaaatt
     1801 agcattttta actgcaacaa attttttctt tccttctccg aaggaaattt ctaggtcttt
     1861 tacttcgact aatttctcag acatttcctt cctcctgttg tgacattttc cttaagattt
     1921 tttgatgcaa atcttgaatg acttctggtt tttgaacttt tggagcctct gggtgtaaaa
     1981 gccatgtttt ggcccaatga gtctcagata cgttaatcgc cggaggtgct ttttcaaagt
     2041 ctaaaaccat agcatattct gagcgaagtg caaaggcatc tccgataatt ggtgaataaa
     2101 gtgatggagg cgttcctgga atagcgtaaa gttcaccaga ttcatctgcc aactgcggta
     2161 agctagacag caaactccat gtataggggt gtcttggatc atagaaaatc tcttcgactg
     2221 ttccaaattc aacaatttct cctgcataca tgacagccac tttatctgca atgcttgcca
     2281 caacacctaa atcgtgcgta ataaagataa tggtgaaatg atattctcgt tgaagcgact
     2341 tcaataactc aacgatttga gcttgaatag tcacatcaag ggctgttgtt ggctcatcac
     2401 agataagaat atctgggcga caagctaaag caatagcgat aacaatacgt tgacgcattc
     2461 ctcctgaata ctcaaatggg taatcttcaa agcgtttttt ggcatttggg atacccactt
     2521 tattcatgta atcaagggcc atttctttag ctttggcatt acttactttt tggtgcttaa
     2581 taatcacttc tgtgatttgt ctaccgatag ttttaatggg actaagactg gtcattgggt
     2641 cttggaaaat cgttgcgatt tttgagccgc gaatctttgc ccactcttta tttgttttta
     2701 aatctgtcaa ttcttgccca cgatagacaa ttgaaccatt agcaatgcgt ccattagact
     2761 ccaacatccc tgtaaaggtc tttgttaaaa cagatttacc tgagcctgat tcccctacaa
     2821 aagcaaggac ttctccttca acaagttcca gtgagacgtt acggatagct gttaaaacac
     2881 gatcacgcac atcaaattct accaccacat ctttggcagt taagattaca ttattttctt
     2941 ttgtcatttt aactcctatc tatgtgaacg tgggtcactg gcatcagcca agttttgtcc
     3001 gacaatgtat agtggtaacg atactaaaat caatgttact aagggaatcc aaaagaggta
     3061 ggcatttgtt gttaagttgc ttgaataatt agcaatcaaa cgtcctaaac ttggagtggt
     3121 ggttggtaaa ccaatcccaa agaaggataa gaaggcctca gaagatacat aaactggtag
     3181 catttgtgac aacatagtca tgataactga aaccaattga ggcaggaggt tcttaacagc
     3241 aatcttgtac atgggtgttc ccaaagtttg actagcaagg ttgtattcta aatcacggta
     3301 acgcaagatt tgaacacgga tggagtaggc gacaccaatc catccagtga tacagaaagc
     3361 tagaatcaaa ttccaaaatc ctgcacctaa tgaataggtc aaaacaatga taataagcat
     3421 agaagggata tttgagataa tgttataaat ttcaatcata actttatcaa atgctttaga
     3481 aactccccat atggctccta acactacccc aatggtgata ttaattagtg tcgctataac
     3541 tgagattaaa atagaattac gtgccccata ccaaacacca tcaaacagag attgcccatt
     3601 tttgtcggtt ccaaaccagt actctgcatt tggccaaata taacgctttg aaaagtcatt
     3661 gatattacta acgtcattaa agtcgtagtt ggcaaacatt ggataaataa agctcatcat
     3721 caagactgtc actaaaatca cgagcataaa gactgtagat tttttagaaa aaaactgacg
     3781 aaacactgat ttccagtaag aataagcagg ggtatcaatc acttcggagg cttcactatc
     3841 gcgctcaaca aatcgaaatt tagatttatc aatcgattcc attacttacc cccttttttt
     3901 gttgacaatt taatacgtgg atcgacaagg gtcatgacaa tatctcctag taaaagtgaa
     3961 acaattgaca agacagtgaa gataaaggtt aatccaacaa tcatagaatt gttagcagat
     4021 ttaatagaat caattaacat tttacccata cccgggaagg caaagacagt ctctgttaag
     4081 gttgcaccac caatagcaag gataatactt gcaggaaccc ctgacacaat tgggaccatg
     4141 gcatttttga agagatgccc tctgtaaatt tcagattctg ataatccttt tgaacgcgca
     4201 aaacgtaccc aatcgctggc ctgaaggtca acaagatagc gacggaacca gataaccgta
     4261 gttggaatat ttaaaattcc taaaataagg gctggtaaaa tataagattt aggatcagat
     4321 gcccccagca ttgggaaact atctggtaaa ccaaccatgc cacctaggaa gcgaacaaca
     4381 tagataacag caatacttgg taaagcaagc atgaaggtca tggtcgctgt tgagaaacgg
     4441 tcaaaatagg tatttttaaa ccgagccata aataaaccaa gaggcaaacc aacgatatag
     4501 gaaaacataa caccaaaaaa accaattaca aaagaattgt gaatcattga tgggtcgaca
     4561 taattattga tggttttagt gtaggaatct cccttaccat agtttacctt ggtgatatca
     4621 tccaatgatt ttggattttt gtagctacgg ctatagatat ccactgacga tttcttagtg
     4681 acacctgatg ggaaggtcac gtcttgaaga gctgttcgtc cttgcccttg tgaaataacc
     4741 tgaagaacag gaatattgct gtatgttgga taagatgttc ctaagtttag ggtaacaaag
     4801 ttttggtgaa gataaggaaa ttttccgtta gtatagagga gatatttatg ttttgtcccc
     4861 gaaccaacaa gtgaccagcc aactgattta tctttttcta gacgaatata cctagctaat
     4921 tttggattat ctttatcctg aatcttccaa gggtgatcaa taacaactag atttgagaaa
     4981 aagttccaaa cacgttcgta aataggaata ttgcgaattg cataaaactg tttgctagtg
     5041 gggaagcgtt ttagctgcca gccattgcca agagaatcaa tatacttctt atagatagct
     5101 ttgttagcac tagttgcttc tgtcgttaca ctactatcta ctttagaagc attatctttt
     5161 aattctttgc ttgaaaaata attgacataa cccatacgtt gaaaagttag attttcatac
     5221 gctacttttt tatctggtgt tgttgtcatt ttattataat tagggtcttg tttaaagata
     5281 aggctggtag gtactagagt atatacgatg gtgtatgtta aagccgttac caaaactacc
     5341 gacactaacg atcgcatgat acggtttaaa atgtattttt tcatagttat cctcaatagt
     5401 tcaaaagaac tccctcacat aaacgagaaa gttcttttga acatcgtttt atttttcaac
     5461 gtgatcagct aacttctcag catattttgc atttgactta gcctttgctt tcatccattt
     5521 ttcttttgca ttttcgtatt gttttgctgt gacaggtttg tcttgaagtt tcattccttt
     5581 atatgctaga ggacctttag accctgccca agagaagccc ccgctaaatg gaacggcttt
     5641 agtaactcgt ggagtgccac ccaatgccac aactggaata tctacggcat tatctgtaag
     5701 gtaggcttgt gcttttgcgt aagctttata gcgcgcatcg ttgtcgtctg taattgctgc
     5761 tgcttcatca agaagagttt ggtaggtatc aagacctgca gctgccacaa catccttatt
     5821 ttgacctgct ttgattccaa gtttttggat aacagatcca ccacctactg gactcatgat
     5881 gtcaaggtag gtccgtggat cttggtagtc tggtccccac catgatgaaa tgatatcgta
     5941 gtcttgttgt tctggggtct cagcatagaa gccttgggct tcgtgagttg atgtttctgt
     6001 ttcaagaaca ttgacaatga cattttcttt accaagagat gcttcaacag attgtttgaa
     6061 agactgagct tcctgaacag ttgctgcgtt tgcttggtca acagggtaat ctaattgaac
     6121 tgggaaggtt acaccttcag ctgtcaaagc ttctttggct tttgcaaact cagcttttgc
     6181 tttttcagga ttatagaaac catcttgagc atcagctaag ttaacgtctt tccattcatc
     6241 accaagtttt gccatttcct tttcaacttc tgaaccaaaa tcactttctc caatggtcac
     6301 aaatgttggt ggcacaagca tgttacgtaa ggcttttgtt ttggcatctt gacctgcagt
     6361 ttgtgcttgg aatgacgctc ggtcaaaagc aaactgaata gcttgacgaa aatccttgtt
     6421 gttaagagct ttcttaccgg catcttgttg tgcagggtct ttcttagtgt ttttgaaaga
     6481 agtgcggttc aaattccatg ttaaatgacg gatatctcca gtcaacattc cgtaagtaat
     6541 gttatcagca tagtttttct tagctgattt gtaggtaggg tcatttgggt aaagtcgtgc
     6601 aacgctgaac tcacccttgt caaagttctt gtagaacgaa cctgggtctg aaccatctga
     6661 gtaagtcaat ttaacagatt ctatcccaac attcttagca tcccagtagt tttcattttt
     6721 atggaattcc atagatgatt ttgaggtgaa ggcgctcaag aagtaagcac cattaacaag
     6781 gattgatgat ggatcggttg taccaaaatc tttacctttt gacttcaaaa atttcgcatt
     6841 aactgggaaa agcacactat aagttgtttt tgaattccag tagctttcag gcttgttcaa
     6901 agtatactga acagttttat cgtcaagggc tttgacacca acttctttaa aatctacttc
     6961 accattttgg taagccttta agttttttat tgaatcttca acaacgtaaa gagcatctga
     7021 tttatcgtca accgcgtgct tcaaaccagt cacaaaatct tctgctgtta ctggggcata
     7081 ttcttcacca tcagccgtat accaagagac accatcgcga agagtataag tataagtcag
     7141 accgtctttt gaaaccttcc aatctttagc aagtgatggt actaaattac catactcatc
     7201 gttttccaaa agaccatcaa ccatttgtgt tatcacatca gtcgttccac cgccattagt
     7261 caaaatataa tccaatgatt ttggatcgtt aacaaaaacg tacttgtagg tttttgtagc
     7321 ttctgagcca cctgaagcat ttttattacc acaagctgcc aaagcggata ctgacaagat
     7381 cgcaacactt acagctgcca accatttact tttcttcata aaagtcaccc ctaaacttta
     7441 tttttcattt tttggcaatt gctaaatgaa attggttaat tgaagacatt atatcataaa
     7501 actttcttaa agaaaataat gaaatgaaaa attatctgaa tatttcgtag aattttcttt
     7561 attttataca tttatctata tgaaagcgtt acactccttt tttaatgagg tttcaattag
     7621 tttaataaag attgtcattc tctcatggta gcgttttatt acatcactac tcttgtgagg
     7681 taagtcatta ccttagacaa aaatatggta taattaaaaa aataatactt gagtaaggat
     7741 aatctataaa tgatcaaacg attaatttcc ctagtggtca tcgccttatt ttttgcagca
     7801 agcactgtta gcggtgaaga gtattcggta actgctaagc atgcgattgc cgttgacctt
     7861 gaaagtggca aagttttata cgaaaaagat gctaaagagg ttgtcccagt cgcctcagtc
     7921 agtaagctct tgacaaccta tctggtttac aaagaagttt ctaagggcaa gctaaattgg
     7981 gatagtcctg taactatttc taactaccct tatgaactca ctacaaacta tactattagt
     8041 aacgttcctc ttgataagag aaaatatacc gttaaagaac ttttaagtgc gttagttgtt
     8101 aataacgcca atagccccgc tattgcttta gctgaaaaaa taggcggaac cgaacccaaa
     8161 tttgttgaca aaatgaaaaa acaattaaga caatggggca tttccgatgc aaaggtcgtc
     8221 aattcaactg gcttaactaa ccatttttta ggagctaata cttatcctaa tacagaacca
     8281 gatgatgaaa attgtttttg cgccactgat ttagctatta ttgccaggca tctcttatta
     8341 gaatttccag aagtactgaa attatctagc aaatcctcca ctatttttgc tggacaaacc
     8401 atttacagtt ataattacat gcttaaaggc atgccttgtt atcgagaagg cgtggatggt
     8461 ctttttgttg gttattctaa aaaagccggt gcttcttttg tagctactag tgtcgaaaat
     8521 caaatgaggg ttattacagt agttttaaat gctgatcaaa gccacgagga tgatttagct
     8581 atatttaaaa caaccaatca attgttgcag taccttttaa ttaattttca aaaagtccag
     8641 ttaattgaaa ataataaacc agtaaaaacg ttatctgtct tagacagtcc tgaaaaaact
     8701 gtcaaacttg tagcccaaaa tagtttattt tttatcaaac caatacatac aaagaccaaa
     8761 aataccgtcc atattactaa gaaatcatcc acaatgatcg cacctctatc aaagggacaa
     8821 gtcttaggta gagcaaccct tcaagataaa catcttattg gacaaggtta tctggatact
     8881 cctccttcta tcaatcttat ccttcaaaaa aacatttcta aaagtttctt tttaaaggtc
     8941 tggtggaacc gttttgtgag gtatgtcaat acctctttat agaataacac aatgcttttt
     9001 gtatgacatt gactgacaga gtacttctgc agtctttttc atttttattt aagcaaacta
     9061 ggctaatcct aacaattttt caaaaaaact tcacattgta ttagcaaagt gatatactga
     9121 aaatgcatta catttaaagg agtcggaaat tgaccaaaag aattatacta actattttta
     9181 cctttatttg cttttcgatg atgcctcttg tccacgccga agatgtcatg gatattacaa
     9241 ggcaagcagg ctacacagtt agtgaggtta atcgaccaaa atcttctatt gtcgttgatg
     9301 caaatagttc agatattctt tggcaagata atattgatat tcctagggat cctgctagta
     9361 tgtctaagat gtttacgctt tacattttat ttgaagagct cgctaaggga aaaattacga
     9421 tggacactac tattacggca actccaaccg atcaagctat cgctaacatt tatgagatta
     9481 gcaataataa tatcgtcgct ggagtagctt atcctattcg tgatcttatt actatgacag
     9541 ctgtgccttc atcaaatgca gcaactgtta tgattgccaa ttatttatca aacaatgatg
     9601 cttctgcgtt tatcgatcgt attaatgcca cagccaaaca attaggcatg actaacaccc
     9661 atttttcaaa cgctagtggt gcagcagcac aagcttttca aggttattat aatcctacta
     9721 aatatgattt atctgcttca aatattacga ctgctcgaga tttgtccaag ttactctata
     9781 ccttcttaag aaaataccct gaaattatct cctttacaaa taaatctgtt gtgcacacta
     9841 tggtaggaac gccatatgaa gaagaatttc acacctataa ccactctctc ccagataatc
     9901 aatttggtat gaaaggagtt gatggattaa aaacaggttc tagtcccagc gctgctttta
     9961 acgccatgat aactgccaaa agaggcaaaa ctcgactcat tactattgtc atgggggtcg
    10021 gagattggtc agatcaaaac ggagagtttt atagacatcc tttcgttaat gccttgactg
    10081 agaaagggtt taaagatagt aagaccttat ccaaaaaagc acgccaaaaa ctcgaaaaat
    10141 tagtgccaca aaccaaaaaa gaaacatcac ctaaacagca gcacttcaaa gccactaaaa
    10201 agcaatcgta cttggaaaga gtcgaagatt ttatgaatca caaccatact ttcttgctta
    10261 tttgcttagc tatctttata attactatcc ttttactaag cctcgttgtc tttgcaatgg
    10321 gacgccaata atgaattatc aaaaacctct gtcaaagcac agaggttttt gatatgttat
    10381 cttacgtgtt taaggcaact aaaaactaac cacttggggt tagtactaca actcataaaa
    10441 ttctatctca aagatctttc agatggataa gagaaaatgc aattaaccga cagaaccttc
    10501 catctcatag gaaatcaatc gattgagttc gaccgcgtat tccattggca attctttggt
    10561 aaaaggctcc acaaatccca tgacaatcat ctctgtggct tcgctttctg ataagccacg
    10621 gctcatgaga tagtagagtt gttcttcaga aatcttagac actttggctt catgttctaa
    10681 cgccacctgt gaattatgaa tttcgttaaa tgggatcgta tctgatttag aaatatcgtc
    10741 catcaaaata gtatcacatt caatatggga aacggatttt ttagattgct tgttaaaggt
    10801 cacttggcca cgataatcta ctttaccacc agacttggca attgattttg acacaattga
    10861 tgatgatgta tgtggagcat tgtgaatcat tttagcccct gtatcttggt gttggcctgc
    10921 gttagcaaag gcaatagaca gcatggtgcc acgcgcacct ggcccatcaa gataaacaga
    10981 agggtacttc atggtggttt tagctcctag attgccatca atccattcca ctgttgcatc
    11041 cgtaagggca cgtgcacgtt ttgtcactag attatacaca ttgtctgacc agttttgaat
    11101 ggtggtataa cgcatgtatg caccgtcaag cgcaaagatt tcaacgatag cagcatgtaa
    11161 gctgttactt gaataagtgg gagctgtaca tccttcaaca taatgaacac ttgctccttc
    11221 atcaacaata atcaatgtcc gctcaaactg accagtattt tcattgttaa tgcggaaata
    11281 agtttgcaaa gggatatcta ccttgacccc tttaggaaca taaataaagg taccaccaga
    11341 ccaaactgct gaattgaggg ctgctaattt gttgtctgtt ggcggaacca gtttggcaaa
    11401 gtattgtttg aacaaatcag gatattcttt gagggcggaa tcggtatctg taaagataat
    11461 ccctagtttt tcaaattcac ccttcatgtt atggtaaacc acttctgact catactgagc
    11521 tgatgctcca gcaagataag cacgttctgc ttctggaatt ccaatacgat caaaggtttc
    11581 ttttattttt tctggaacat catcccaaga acgagctggc ttatcagatg ctttttgata
    11641 gtaaatgata tcatcaaagt taatatctga taagtctgct ccccaggttt gcatcggcat
    11701 tttattaaag gtttccaagg attttaaacg aaactccaac atccactcag gttcattttt
    11761 ggcagctgat agttcgcgaa ccactgcctc actcaatcct tttcctgtag aataaatggg
    11821 ctctacatca tcgtgaaatc caaattggta gtcccctaag tcaattggct ttggctctac
    11881 tttctcattt atatcagaca tttttccctt cctttacatt ttggtccgtg aggtgctgag
    11941 cattggcact tcgtttaata gcttccttga gagcattcca agctagggta gagcatttga
    12001 tacgctgtgg aaattttgca actcctgcca acaattctgc ttcacctagc tctttttgag
    12061 caggattttc ctgtccttgt accatctctg aaaaaatatc agctaacgcg agtgcttctt
    12121 ctttactttt accaataaca gcatctgtca tcatgcttga tgaagctgtg gaaatggtac
    12181 agccgttgcc tgcaaaagca atatcttcaa ttttatcttc gtcaaactta acggtcaaag
    12241 aaatcacatc accacaagtc ggattattca gttgaacagc ctctacgcca tctagttgcc
    12301 catgatgatg tggacgtttc gaatggtccg ctaccacagc catgtataga tggttcagtt
    12361 tagagagtgc cattgaaaaa ctcctttgct tttagaattg cttcgactaa acggtcacaa
    12421 tctgccttgg tgttatagat ataaaaactt gctctaacag ttgctggtac acctaaataa
    12481 ctaagaagag gttgggcgca gtggtgccct gctcttactg caacaccttc atagtccaag
    12541 gctgttgcca agtcatgagg atgcaaatca tccagattaa aagaaatcag accagatctt
    12601 gcactaggct ggcttggtcc atatatggta agcccctcaa tagcttctaa tttcggcaaa
    12661 acataggcta ttagttctgc ttcatgcgca tgtatatcag ccatgcctag tctctgaagg
    12721 taagaaatgg ctgcgcttag cccaatagca ccagctatgt gaggtgttcc tgcttcaaac
    12781 ttccagggca attctttcca agtggcctct tgttcgtaaa caaaattaat catttctccg
    12841 ccaaattcaa gaggctccac ttgattcaaa agctcttctt tgccgtaaag aacacccaaa
    12901 cctgttggcc ccaacatctt atgagctgaa aaagcaaaga aatcacaatc caagtcttga
    12961 acatcaatag ccaaatgtgg aaccgactgg gcaccgtcaa caacaaggta ggctccttta
    13021 gcatgtgcca gcttggcaat ttctttaatg ggattgatgc aaccaagaac attggagaca
    13081 tgtactaggc taacaaaacg tgtttttgtc gtcaatttgt ttgccaaatc gtccatgtca
    13141 agttggccat cttttaaata aacatagact aaccttgctc ctgttttttg acaggcttgt
    13201 tgccaaggaa tgatattggc atgatgctcc ataatcgaaa tcaacacctc atcttctggc
    13261 gtcaagacct gctctgcaaa ccgagcaacc caattcaaac tggttgttgt tcctctggta
    13321 aagagcactt ccttgcttga tttagcatga ataaagtcag caacctgctg gcgactggcc
    13381 tcatatttgt gcgttgcacg ttcagccaag gtatgaactc ctcggtggac attagcatta
    13441 tcttcttgat aataggattg caaagcctca agaacaagcg ccggtttttg tgtggtggcg
    13501 gcattatcca aataaacaag gggttcatca ttgacttgtt gatttaagat ttgaaagtct
    13561 tgtttgatgt cttttgcgtc tagcaatact aacctctttc tttttggcag taggtcttaa
    13621 cgattaagca atttctcatc taaaacctta ataatctctt ggtggactga tggaatagga
    13681 atttcagcga taaccgctcc taggaatcct ctaataacca atcgttctgc tgtttcttga
    13741 tttagtcctc gactcatcaa gtaatacata tcttcagggt caacctgacc gatagaagct
    13801 gcatgacctg ctgttacttc attttcatca attaagagga ttggattggc atcggctctt
    13861 gcttggtcag aaagcatcaa aacacggctt tcttgttgag catcagctcc cttagcgcct
    13921 tttagaatat gaccaatccc gttaaacgtt aaggtgccac gttccaaaat cacaccatgc
    13981 tgtaaaatat gaccaaccgt acgttgacca tagttggtca cgcgcgtgtc aataccttgt
    14041 acctgacgac cacttgaggc tgcaacaact ttcaaatcag cttgtgagcc ctgaccaatc
    14101 aaatcactgt caaaatcagc aatgacattg ccttcattca tcacagctaa ggcccaatca
    14161 atgttggcat ccttctctaa acgtcctcga cggctaatat aggttgtcac tgaaggacct
    14221 aagcggtcga tagccgagaa tttaatctgg ctgcctgctt gagcaatcac ttctacactg
    14281 atattagcgc tgatcttttg agtggcattg ccaatagatt caaaacgctc taaataggtg
    14341 aacttacttt cttttcctgc aatcactaga acatgcttgt taaaaggaac gtcactgtca
    14401 ctatcttgta agaaaatagc ttcaatagga gttgtgattt ccaagtgatc aggaacgtag
    14461 agcacggctg cgctattaaa ataagcagtg tggtaggcag ctagtttgtc ttcatcaaaa
    14521 gctaatgcct gaccaaaatg agcttcaatt acttctggga tttcctcaag cgccgtataa
    14581 aaatcactga aaacaactcc cttgtcaatt aacgccattg gtaactgttc taagactgtt
    14641 tgcgtgccta cctgaacaag ctttgggtta tctccaatag ctataaaatc tggaacacta
    14701 gctagacttt cattttctgt taaggtacca tctcctagat tccaacggtg aaatttaacc
    14761 ctttcgatgg ttggtaactc taattctggt atggcttcta atgccgctaa acgccgctct
    14821 tgcagccaag caggctcagc gtgggcttgc gaaaaagcca ctagtttttc ttttgtcatc
    14881 tgtcaatcct ttgtctctgg tttttaaatt ggctgggtat atagaacatc acctagcttt
    14941 ttgtagaaag ctaaagtaat tgtctccaaa aacttaactt tcttccttat actcgattcc
    15001 cagatcctgt gcaatacctg cgtagccttc tttttcaaga cgagtagcca aggcagcatc
    15061 accagataag acaatacgac catccatcat aacatgaact aggtctgggg taatgtaatt
    15121 caacaaacgt tgatagtggg tgataatcat agctccaaag tctttcccac gcatctcatt
    15181 aaccccttta gagactactt ttagggcatc aatatcaaga ccagaatcaa tttcatctaa
    15241 caaagcaaat ttaggctcta acatgagcaa ttgaagaatt tcattgcgtt ttttctcccc
    15301 accagaaaaa ccttcattga ggtaacgctc tgccatctct tctttcatac ctaacaaagc
    15361 cattttctca tcaagtttgg tgataaaatc tcgcacggaa atcttatcct catctgcctt
    15421 accggcattc attgctgcac gcataaattc agcgttggtg atccctggaa tttctgaagg
    15481 gtattgcatg gcgagaaaaa gtcccagtct cgcacgctca tcaacttcta gatcgagaat
    15541 attgaccccg tcaagcaaaa tttgcccttg ggtcacttcg tagttaggat ttcccataat
    15601 agctgctgaa agggtagact ttcctgtccc atttggcccc ataatggcag ctacttcccc
    15661 agttttaaga gttaggttaa cccctttcaa aatctcttta ccttctattg aaacatgtaa
    15721 attattaatc tcaagaattg acatgataca ccccttattt tctctgtcat ctataccatc
    15781 tcaagaaaag acagtgtcat ttgcactgct ttttttataa tggtcactgc atctattata
    15841 gcaaaaaaag ccttactcgg cttttttagt gtttcaaatc cttcttttct ttccatttca
    15901 gaagcattgc ttgacgataa tcactattac caataaactt taacaagtta aacaaaggcg
    15961 ttcgcttttc accccagatc tccaatcctt caataaaaac ttctaaacca aataaaagtc
    16021 caagcatcaa gaggacgcca ccaattcgac tagaaacatt taaaagtaaa gaaataaggg
    16081 aaaaaagcat ggtaatacca taaactacta agacagctcc tcgatgagta aagcccattg
    16141 ataagagtcg atgatgcagg tgcatcttat ccggctcgta gaatttttga cctgataaac
    16201 tacgtcgaat aatagccacg atggtatcca taatgggtac accaagaata ataacaggtg
    16261 tcaccacagc cacagccgtt gaatttttca atccttgaag agacaaaacc cctatcataa
    16321 agccaataaa gagggctcct gtgtcaccca aataaatcat agctggatgg taattataag
    16381 gaaaaaatcc tgcaatagca gaaatcaaga ccaaaatggt taacgtcaaa aagaaatcct
    16441 tttgaggtaa aaagaaataa gatacaatag ccatggtcac taaactaata atagagaccc
    16501 cactaaccaa accatccaaa ccgtcaatca agttaatagc attagtgatg gaaacaatcc
    16561 acaggactgt taagaataag gttaagaaag gaccaaaaac taacaacggc cctccaaaag
    16621 gaattttgaa gctatcaaat ttaaagtcgg taaaagccca gacaatcact gcaccaatta
    16681 gaataccaaa catctttaat ttaggactta actcatacaa atcatctaaa aaaccagtaa
    16741 gggtaattac tgtagcacca atcacgacag gtaaaatata actgaagtag gtctgaccaa
    16801 aaaacatggc gcctttagaa gcaatcggaa taagtcccaa acttgctact aaaaaagaca
    16861 taaaaatagc taatccacca ctggttggca tcggaacctt attgacccgt ctggcattgg
    16921 gattgtctac tgcacccaca cgaaaggcta aaaagcgaac aagaggggtt aagaataagg
    16981 acattaacaa agcccctatc agaacaagga cataatctat tgtgaatgaa aacatactat
    17041 tttatcccaa ctcaatcttt tgtaattgct caacagcacc atcaagcatc aattgtaagc
    17101 catgctcttg taaataagct cttgtttttg atccagggtt tgcatgctca atcaatctcg
    17161 catacatgac attcgcaaaa taagatggtt gttgctgaac atctaataaa atagtcatat
    17221 ggtagcagtt gctcccctta tataactctg aagcttctat cgaaaaatca atcgttttag
    17281 caaaagccac tgcctctgta atcgttgaaa aatccaatac ataatggaca tagtctaaag
    17341 gttctgactc atgattagtt gatggatcag ccgcctcaga ctgattagct agagtggctt
    17401 caacaacatc ttccattatc tcttcaattt tttccaattt ttcatgagct ttgacatctc
    17461 ccttttcacg catggattgc tccaagctct tgaaaaaatc ttccggagtc atttgggaca
    17521 tatcaccaaa ctctgctaaa tcttcaagat taatatcttt atttatctca gatttggtaa
    17581 caaaaacatc tagacggtcc ttgcgtggag tcactcgaaa actaagcata ccactatctt
    17641 taaaattatc tggaagatcg agttcgtcca tcacagaata gaaaaactct tctgtttttt
    17701 cttgaggaat caagaaatct ttcaactcca ttcctctttc ttctaaatcg tccatactaa
    17761 ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattctcaat acctcgcacg
    17821 cgtagtcatt ttattatact agaaatgctg taatttcgca atttatgact aactcctctt
    17881 ctacaaaagg aaatttaaaa agcgacagtc cccaagatct gtcgcaacat cctaaacgat
    17941 atgtaagttt aaaaaacaaa tttaaagaag ctataaataa gtaaaaggct tcctaacaca
    18001 atacggtatt ttccaaaaat ggtgaaatcg tgtttcttaa cataatgtgt caagaaccta
    18061 atcgccaata aactaaccac aaaagcggtc aagctagcca ctaaaagaat aaggacttgt
    18121 gcaaaatcaa ggtgatggcc atcaagaaaa aatttcacag cctttaatcc actatatcca
    18181 aacatggtag gaatggccaa aaagaaggtg aaatcagcgg ccactgttcg actagttcct
    18241 aaaataatag ctcctaagat ggtagcccct gatcgactag taccaggcac aatacttaag
    18301 acttgaaaac aaccaatgaa gaaagctgtt ttgtaagaca ttctagctaa gtcagtgacg
    18361 gcaggttctt gttgagcatt ttgtttttca atccagataa aggcaatccc gtagacgatt
    18421 aaagcgatgg caatcggaac cataaaataa aaatgtgctt caaaccaatt atcaagagga
    18481 accgctatta aaatagaagg aatacacgca atcaccactt ttagccataa ttgccaggta
    18541 agctgtactt ctcttgctgt tttcccaggt tgaaagggat tgagacgttc aaaataaatc
    18601 aacataacag cgataatcgc ccctagttga ataacgatat taaacatttc tataaaagcc
    18661 ttatcctgat ttagtcggat aaattcctgc actaaaatga ggtgaccagt gcttgaaact
    18721 ggtaaccatt ctgtgattcc ctcaatgatg ccaaagaaaa tggcttttag caattcgatt
    18781 attaacatgt tttctcctta ttaaccactc ttattgtgat tttctaaact gtgattaatg
    18841 ccaagcagct tttttaaaag gcaccgccgc cgcctcctcc gccaccgcca gagaagccac
    18901 caccaccact aatcccgcct ccggaagaga ctgagaaatt tgaggaagtt gtagctgaag
    18961 acaagctaga cacaaaggtt ggtgtcgtag catacattac cattgataat tcacctggtc
    19021 gaacagcttg gtaaacctca ggtaaggcaa tacgatggac tttcaaatag cgttccactt
    19081 tcttagcgta accaaataag gtggcataaa ccaaaacacg gttccaaaca accaaacctt
    19141 caatagcaac atcctcaaat ttgtcaatgt ctcgtatcat gtttttaaag ctctgccatt
    19201 gatgtaaccg aacacccccc tcaggtgttt caatacccaa tttcttgtat tgatctaact
    19261 tcaggctaat gtaaaagcca aggcacatca ttaacaccat taaagcaagg taaatgaggg
    19321 ctaacccact tcctttcata gtcagataga tcaataaact actattcaga acaactaaca
    19381 agcagcctaa cccctggaca ctatgacttt ttcgtttctc tgccggggtc atttgacgat
    19441 aagtatctgg caagtttaac tttttgatag tttctaggac attgtttgta atagttgccg
    19501 acgctttttt catcgcctta atcacctgct cagacgattg acggacttct tgctcgagct
    19561 ttttaccttt gtacgttttc tttaattgtt taatggtatc agcatcataa tggtattgac
    19621 taaacaattg atccaccggc aatgtcacct tgtttccaaa agccatatct aagaaggcag
    19681 cttcctcatc tgtcacacga tctaactgac tgatttcaag ataagctttc ccttcttctt
    19741 tcgttaataa aagcaccttt tggtcgatca gatccaacaa ggtagcttga acaagggcct
    19801 caaaggtcac tcctttaggg atcaataatt tctggctttc tgatgctgta ggggataaat
    19861 aggcaaaact ctgtccataa atcgcttgtg tcaacacaag aggcgaaaga tcttcaggga
    19921 cttcgtaact gtgatctgta tggttagcca aatgataacg attgaattgt ttctttaatc
    19981 ttgtaaactg tattaactgc gaaagaagaa aacctacctc taccagagga atgactttgc
    20041 caaatagcag ctgtaacaag gtccttcgtc tggaaatctt agtttctaac gctacaattt
    20101 tattcttttt actcgttgaa acatcaactg gctcttttcc caataatgct tttttatccc
    20161 aataagcatg caattccaat tgccctgaga cattcttggc attaatctga tagcgactgt
    20221 taccttcttt taacacttga ggtttctttt ggtaatatcc tctgtgagcc catagattag
    20281 aatcctgaat atcagttggg gtagtgacgg tcaaactcac cttttctaat gttttgtccc
    20341 aatcactaat cggtgtccaa ttcagctctg ccacgtcttg ataagctgtt aaaaggtggt
    20401 gcagttgcca gataaccttg acgtcaacct tatcaccagc ttggccagca ttataaagtt
    20461 ttaaacgata gccatctcca aggtcactaa actcttgact aacaggtacc tgttgaccat
    20521 tctgatatac ctcaacttta ggcttttggt caatagcaaa gcccgctggc aaatgacctg
    20581 tccggcccag cgaaatatac tggccgttat aagaagtgtc aaattgatag gttacttttt
    20641 gctcaaaccg agcagtattt tcttttgata acagtaactg accttcatag ttggtgatgc
    20701 tatagtctac atcagctgct tttattcgta tccctaaaag actgaagcag agcacaagcg
    20761 tcatcaaaat ttttttcatg gcaacatcct ctttctgccc tcattttacc atattttaag
    20821 gagatgacaa aacctaaacc aagtccttca tcttattttt actcattatt ttgaatattt
    20881 ttccatattt caacctattc actgataata tattgaaata ggatgcaaat tgctgtaaaa
    20941 taggtctgaa tactattttt gaaacaggag acctatatga aaaagctaat ccttagctgt
    21001 ttggtcgcct tggcccttct gtttggagga atgagccggg ctcaagcaaa ccaatattta
    21061 agagtcggaa tggaagcagc ctatgctcct tttaactgga ctcaagatga cgcttcaaac
    21121 ggggctgtcc ctattgaggg aactagccaa tacgccaacg gttacgacgt ccaagtcgct
    21181 aaaaaagtcg ctaaagctat gaacaaagaa ctgttagtcg ttaagacctc ttggaccggt
    21241 ttaattccag cattaacttc tggaaaaatc gatatgatcg ctgctggtat gagtcctacc
    21301 aaagagcgta gaaacgaaat tagcttctca aacagctact acactagcca acctgttcta
    21361 gtcgtaactg ctaatggcaa atatgctgag gcaaaaagcc tcaaggattt ttctggagct
    21421 aaagtaactg cccagcaagg cgtttggcat gtcaatctct taactcaact aaaaggtgct
    21481 aagttacaaa caccaatggg ggatttctct caaatgcgac aagcccttac ttcgggtgtt
    21541 atcgatgcct atatttctga acggcctgaa gccatgactg ctgaagctgc tgatagccgt
    21601 ttgaaaatga tcactcttaa aaaagggttt gctgttgctg aatcagatgc tgctatcgct
    21661 gtcggaatga aaaaaaatga cgatcgtatg gcaactgtca accaagtgct tgaaggattt
    21721 tctcaaacgg atcgtatggc cctgatggat gatatggtta ccaaacaacc cgtggaaaag
    21781 aaagccgaag atgctaaagc atcatttcta ggccaaatgt gggctatttt taaaggtaac
    21841 tggaagcaat tcttacgtgg aactggaatg acccttctga tttccatggt cggaaccatt
    21901 acaggtctct ttattggatt attaatcggt attttccgta cagctcctaa agctaagcat
    21961 aaagtagccg ccttgggaca aaaactcttt ggttggttac tcactattta tatcgaaatc
    22021 ttccgtggga cacctatgat tgttcaatct atggttatct actacggaac agcgcaagcc
    22081 tttggtattt cgatcgaccg taccctagcg gctattttta tcgtatctat caatacgggt
    22141 gcctatatga gtgaaattgt tcgcggtggt attttcgctg tcgacaaagg tcaattcgaa
    22201 gcagcaactg ctcttggctt tactcacgga caaaccatgc gtaaaatcgt gctaccacaa
    22261 gttgttcgca acattttacc agcaacaggt aatgagtttg tcatcaatat caaagatact
    22321 tctgttttga atgttatctc tgttgtggaa ctttacttct caggtaatac cgtagccaca
    22381 caaacctacc aatatttcca aacctttacg attatcgcca ttatctactt tgttcttacc
    22441 ttcacggtga cacgtattct tcgtcatatt gaacgccgtt tcgatgccga tacttacacc
    22501 actggagcaa accaaatgca gattgcggag gtctcaaatg tctaactcaa ttattgaaat
    22561 caaaaacctc aaaaaatctt acggcagcaa tgaagtactc aaagatatct ccctttctgt
    22621 taacaaggga gaagtgattt ccattatcgg ttcttctggt tctggaaaat caaccctcct
    22681 gcgctcgatc aatcttttgg aagagccaag tgccggtcaa atcctctttc atggtgaaga
    22741 tgtccttgct gaacactaca acttgactca ctaccgtgaa aaactaggca tggttttcca
    22801 atcctttaac ttgtttgaaa acctaaatgt attggaaaat gctatcgtcg ctcaaaccac
    22861 cgtcctcaaa agagaccgtg cacaagccga acaaatcgct aaagaaaacc tcaatgcggt
    22921 tggtatgaca gaacaatact ggcaagccaa accaaaacaa ttatcagggg ggcaaaaaca
    22981 acgggttgcc attgccagag ccttatctgt caatccagaa gccatgctct ttgatgaacc
    23041 aacatcagct cttgatcctg aaatggttgg tgaggtcctt aaaaccatgc aagacttggc
    23101 aaaatcaggg ttgaccatga ttattgttac ccatgaaatg gaatttgctc gtgatgtttc
    23161 tgaccgtatc atcttcatgg ataagggatt gattgctgaa gaaggaagtc ctcaacaaat
    23221 tttcgagaat cctacacaag atcgtaccaa agaattttta caacgcttct taaaataaga
    23281 taaaggatcc aactatttct ataccagttg ggtctttttt caattcaaaa agaatttgtc
    23341 ataaaatact ttaccagtta actattttat gctatactta tttttgttaa cgttaataat
    23401 ttatatttag gaggataata tggcagaaaa aactgactta tcgtcagctt acagaagact
    23461 gaaaagtccc aatattaaaa ccagaaaacg tgctctgaag attattcacg agtacaaacg
    23521 ttacggtaaa aaataagatt ttacttttta tctctccaaa tttaagtcag acaaaaaaag
    23581 gctaagacac cccttccatc ttagcctttt tgtatacagt ttattaaggg aactatttta
    23641 aaatatcttt tatgctagag tctagaatag ttcaaaacgt taaaatcata catttaaggt
    23701 agtgtttaaa gtatacgaaa aagaactcag cataaaccaa gctctctttc gttataacta
    23761 attatttagc aatttttgcg aagtactcaa gagtacgtac aagttgagca gtgtaagaca
    23821 tttcgttgtc ataccatgat acaactttaa ccaattgtga tccgtcaact tccattactt
    23881 tagtttgagt tgcgtcaaac aatgaaccgt atgatacgcc tacgatatct gaagaaacga
    23941 ttggatcttc agtgtaaccg aagctatcgt ttgaagcagc tttcatagca gcgttgattt
    24001 cgtcaacaga aacgtttttg tcaagagtta caaccaactc agttactgat ccagttggaa
    24061 caggaacacg ttgtgcagca ccgtcaagtt taccgttaag ttctgggata acaagaccga
    24121 tagctttagc agcaccagtt gagttaggaa cgatatttgc agcaccagcg cgtgcacgac
    24181 gaaggtcacc accacggtgt ggtccgtcaa ggatcatttg gtcaccagtg taagcgtgga
    24241 ttgtagtcat aagacctttt tgaataccga atgcatcgtg aagagcttta gccataggag
    24301 ctaaacagtt tgtagtacat gaagcacctg agataactgt ttcagtaccg tcaagaatgt
    24361 cgtggttagt gttgaaaaca actgttttaa catcgtttcc accaggagct gtgataacaa
    24421 cttttttagc accgttagca tgtaagtgtt tttcagctgc ttctttttta gcaaagaaac
    24481 cagttgcttc aagaacgatt tcaaccccat cagttgccca gtcgatgttt tctggatcac
    24541 gttcagcaga aactttaatg aagtttccgt ttacttcaaa tccaccttct ttaacttcaa
    24601 ctgttccatc aaaacgacct tgagttgtat cgtatttcaa caagtgtgca agcatatttg
    24661 gatctgtaag gtcgttgata cgagttactt caacaccttc gatgttttga atacggcgga
    24721 atgcaagacg tccgatacga ccgaaaccgt taataccaac tttaactacc attagtgatt
    24781 tcctccttat gaaaatcaaa agaatattat ttagagggaa tgctccctac ctattgtgaa
    24841 aagattaact tacagtcatc tgcaacaacc tttcaacaga actattatat aactatttca
    24901 gaaaaaatgc aaataaatta gctattttca taaagggcag cttctttctt ctagccttca
    24961 aaacccacca aatataggaa agggctttct tttttctatg ttctattctg taatttatct
    25021 ttttattggg aaagatttcc aaaacttcaa actgtactat aacgttctgt tacactaaaa
    25081 aagaggttag gatagttatc ctcaacctct tagtggtggt tattcacctt tgtttttctt
    25141 aatgatttct tcttgaactg acttaggaac atcttcatag tggtcaaata ccatcatgaa
    25201 tgtaccacgt ccttgagtag cagaacgaag aactgttgca taaccgaaca tttcagcaag
    25261 tggaacataa gcacgaacga tttggctgtt accatgtgct tccataccat caacgcgtcc
    25321 acgacgagct gtcacgtgtc ccataacgtc tccaagattg tcttctggag ctgtaatcgt
    25381 tacaagcatc atcggctcaa ggatagctgg ttgtgctgat ttagctgctt ctttaagagc
    25441 aagagatgct gcgatcttga aggcagtttc agatgagtcg acatcgtggt atgaaccatc
    25501 gtaaagttta gctttaacgt caaccattgg gtaaccagca agaacaccgt ttgccataga
    25561 ttcgatcaac cctttttcaa cagctgggat aaattcacga ggaaccacac caccaacgat
    25621 agcattttcg aattcgaaac ctttaccttc ttcatttggt gtaaattcaa tccaaacatc
    25681 accgaattga cctttaccac cagattggcg tttgaagaat ccacgagctt gtgtagaagc
    25741 acggaatgtt tcacggtaag atacttgagg agcaccaacg ttagcttcaa ctttgaactc
    25801 acgtttcata cggtcaacaa ggacatcaag gtgaagttca cccataccag cgataactgt
    25861 ttcaccagtt tcaacgtttg tttcaacacg gaatgttgga tcttcttcag caagtttttg
    25921 aagggcaaca cccatcttgt cttggtctgc tttagatttt ggctcaacca tcaactggat
    25981 aactggttct ggaacttcga ttgactcaag aataactttt gctttttcat cagtcaatga
    26041 gtcaccagtt gttgtgtctt tcaaaccaac agcggcagcg atgtcaccag cgtaaactgt
    26101 ttcaatttct tgacggctgt ttgcgtgcat ttgaaggata cgtccgatac gctcacgttt
    26161 accttttgat gtgttcataa cgtaagaacc gctattaaga acacctgagt aaacacggaa
    26221 gaatgtcaaa cgacctacga atgggtcagt catgatcttg aaggcaagag ctgcaaatgg
    26281 ctcttcatca gatgctggac gttcttcttc agcatctgta tccgggttaa cacctttgat
    26341 tgcagggatg tcaagtgggc ttggaaggta tgcgataacc gcatcaagca tcaattgaac
    26401 acctttgttt ttgaaggcag aaccacaaag tactgggaag aattcaacgt tgattgttgc
    26461 tttacggata ccagcaatca attcgtcgtt agtgatttct tcaccttcaa ggtatttcat
    26521 catcaagtct tcatcagttt cagcaactgc ttcgattaat ttttcacggt attcttgagc
    26581 ttgttctaag tattcttctg gaatatcttc ttcaaggata tctgtaccaa ggtcgttggt
    26641 atagatttct gctttcatct tgatcaagtc aatgatacca cggaaatcat cttctgcacc
    26701 gattggcaat tggattgggt gtgcatttgc ttgaagacgg tcatgaaggg tttgtactga
    26761 gtaaaggaag tcagcaccga ttttatccat tttgttggcg aaaacgatac gtggaacacc
    26821 gtattcagtt gcttgacgcc aaactgtttc agtttgaggc tcaacacctg attgtgagtc
    26881 aagaacggtt acagcaccat caagaacacg gagagaacgt tgtacttcga tggtgaagtc
    26941 cacgtgtcct ggtgtgtcga tgatgttaac gcggtgacca tcccattgag ctgttgtagc
    27001 ggcagaagta atagtgatac cacgttcttg ctcttgctcc atccagtcca tttgtgatgc
    27061 gccttcgtgt gtttcaccga ttttatgaat tttaccagtg tagtaaagga tacgctctgt
    27121 tgtagttgtt ttaccagcat cgacgtgagc catgataccg atattacgag tttttgcaag
    27181 tgaaaattcg cgagccatgt gtttctccta tttttttagt ttactctttc attatagcac
    27241 tatttagcaa aaacggatag gcaggaccta cccgttatct aaatatttgt tggtaaagat
    27301 aatatctatt gcctgtataa ggcttggtat cttattcatt gaactcaggc taaacgctgt
    27361 gtgaaaaaga taaactttcc tagaaacaaa ggtttcttcg tcaaatttcc tattttcact
    27421 ttgcgttcta tacgccttcg tatcttatta attgagttca agctacaaat gtctgccaca
    27481 aagataaaat tacctagaaa ctgaagtttc tgcgtcaatt tccctatttt ggctagcatt
    27541 tgtttgacgc taaaatatct tatattacca acggaagtga gcaaaggcac ggttagcttc
    27601 agccattttg tgagtgtctt cacgtttctt aactgatgca cctgtgttgt ttgcagcatc
    27661 catgatttct ttagcaagac gatctttcat agtgtgttca ccacgagctc gtgatgcgtt
    27721 taccaaccaa cgaagtccaa gtgttgtacg acgttctgga cgaacttcaa ctgggacttg
    27781 gtagttagaa ccaccgacac ggcgtgcgcg tacttcaagt acaggcatga tgttgtccat
    27841 agctgtttca aatacttcaa gagcgtcatt tcctgttgct tctttgatag cgctgaaagc
    27901 atcgtaaacg atagtagcag ctgtaccacg tttaccgtca agcataacac ggttgataag
    27961 acgtgttacg atttttgagt tatataatgg atctggtaat acttcgcgtt taggcgcttg
    28021 atttttacga ctcattttct cttatccccc ttctattatc cttttggacg tttcgcaccg
    28081 tatttagaac ggccttgttt acggtcagca acacctgcag tatcaagtgc gccacgaacg
    28141 atatggtaac gtacccctgg aaggtctttt acacgtccgc cacgaataag aacaacactg
    28201 tgctcttgca agttgtgtcc gatacctggg atgtaagctg taacttcaat aaggttgctc
    28261 aaacgtacac gagcgaattt acgaagggct gagttaggtt ttttaggtgt cattgttcca
    28321 acacgagtag caacgccacg tttttgtggg gcagccattt tagtttgaac ttttttgtga
    28381 ctgttgtaac caatgttcaa agctggtgaa tctgattttt caattttaga tttacgtggt
    28441 ttacgtacca actggttaat tgtaggcatc tacattctcc tgtgtttttt tatttttggt
    28501 tgatatagca cttggtgaca gcccatatcc ggtgcacttt ttgcaacaat tgtcagcacg
    28561 tctctgtaca cttttgagag accaaaagta aaaagtaccg tctaatatag taacacagac
    28621 ggtacttcat gtcaaataga atttttcctt tgatgcaatt gcttatgacg aatgcatcac
    28681 ctagattcct tacggaacct aaatcctgtg aggccgacag ctgccaacat gacgactcct
    28741 gctttaagag ctctttgagt actttcatca acatcagaaa tgagattgct cgttgtagaa
    28801 gatcctgagc cataagatgt cttagatgag ggctgagtaa tcgaagatgt gattttagac
    28861 acaatggcat tacttgctac catttcagag gtttggccaa caagcgcttc tgctacaaga
    28921 cttgtatttt cagcagctaa tcttgctgaa gcttctaata gttgtttcgt ttctttaacc
    28981 atttcttgaa caagcggagt agtctctacc ttactatatg atagcggttt tacgcccgta
    29041 agagatggag ctacttgcaa atcaggcaca gtagctatat cttcgtctaa gtggcgatat
    29101 tccttttcat tagctaaggt tttaagcaaa gtcaactggt gttctgtggt agcaatagta
    29161 gcttctagac tgctttgttt agcttgtaag gctgctaaag cttcttgtgc atttaacaaa
    29221 gatgaggtag ttttagccaa atcttgctta gtattatcaa tgcgctcacg tatcacttga
    29281 aggcggttag gattcaattt aaagtccttt aagtattgca aatgagcttt tttagccacc
    29341 agtgctgtca ctctggctgc ggcttgctct gctaaggctt ctgtctggtg cagtgcggct
    29401 ttcaacgatg ctagcttagc taatgattga tcacgagtag cttcgagttg tgcttgtttt
    29461 gctttagctg ctagtaattc tgttctcaaa gaacctttag tatcatttaa ttgtctcact
    29521 tggaggttta agctgtctga ctgcttaagt gtgcttgcta atttaccttg aagttgactt
    29581 actttagctt gggctgccat aatatcagct tcttgatgaa tagccgacaa acgattttct
    29641 aatgagctta cttttccttt gatcgctgca atagtatcag atacagtgcc tactctttgg
    29701 gcataatctt ttgtacttcc aacggctttt ataggggtct tattaaagcg ttgatggtta
    29761 gcaatgttag actctggaaa cattacaaag tgttcattca aagatcctac attgctggtt
    29821 gaaaatccaa ggtaaacagg cgcattaggg ttatgtttat ctacacgtaa aaagttaata
    29881 gcatggccgt atgtatttcc gtgtaaatga tctgtaaaga gcatatactt gatactgtca
    29941 taaataccac gtttaatacc attcacagta tgcacatcgt taaaagcacc gatattctcg
    30001 tacatgttat catcatttcg aatgagccct gacgctccgg cagagtcttc aataatagtt
    30061 ttatcatgag gcccaacacc ataatgccct gatacccctg gctgtccgta gacaaatgat
    30121 ggtcttgtat taccatgagt tttcttatag ctggtactaa gtaatcttgc aaattcttgt
    30181 gatcctgctg taacagtaac tggtggtaga cctaattgtc ttcttacact attaatcatg
    30241 tgagctgcaa actgcgctag ctcattttgc acttctggtg tcaaattatc gggatcaaca
    30301 aagcgattac gatctgctgg aatatcttgg tattgattta attgattacc tggactagct
    30361 ttggcaataa tttgatctgc atgctctttg taataattat tgtaactagc tgatccaata
    30421 taaccactag cttctaattt tttaagttct tcaagaggat agccttgcgg tgctttcatg
    30481 gtattattac ccacaatgct atcttgagta gacggagctg aggatttaag acgactaagt
    30541 tctgcctctt tttctgctag agcagctttc tgagctgcca actcttcagt caattgcttt
    30601 ttaactttag ctttttgatt ttctaagtca gctttagcct tctccaattc tgagcttaat
    30661 gcttttgtat tatcattagc cgtttgagct gctttagtga tagcatcagg attgctaatc
    30721 atagcattga gcttagcaat attttgttca gacgttttga cttgttccac taaatcttga
    30781 gctcgagtag tttctgctga aatgctagct ttttgttctg acaatgcagt ctcttttgaa
    30841 tgttgatctg cttgagcatt atgaagctct gtttcagtag ctgttaactc tctttgatgt
    30901 tcggctcctt gggctaatag cgtctcctca ctacttgcaa gagtattagt gtaaatttct
    30961 tgtgcagagg ttaaagcttt ttgttcatta tcttgctgct cttttaagtg gttgatttca
    31021 gcagtagttt ttgtcagagc ggtagcaagc tctgtcagtt ctgctttttg ttgactgaga
    31081 gttttttcaa ctgcatcaat agttgccttt gcctcttgaa ttgtttctgg ttttggtaaa
    31141 ctatcgtcgt gagtattact cgccttcgtt tctcctgagg ctctatcatc tgctttgact
    31201 tggtgagata cgcctacact ggcactcaat aaagcaattg ttgaggttaa agcaattttc
    31261 tgcttaactt ggtttggctt cgtttgttct aagtccattc tctctccttt ttccatttat
    31321 cgaaaatatt accaacttct acaacaacat tgttgttttt gacatcaatc tctgaaactt
    31381 tcagcaatga tttgaaggtc atttgctcac gctctgattg agcgttttct gcaaacacag
    31441 caacaccaac taaagtgctg tcaaattctg tcaagagact gatcattcct gtaatcgtcc
    31501 ccccgccctt caagaaatca tctacaatca atacacgact attgggtttc aaactacgct
    31561 ttgacagaaa catcttttca atacgatcac tagaagcact cgcataattg acagacactg
    31621 tcgatccttc tgttattttt aaatcacgtc taacaatgac aaaaggaaca cttaaaatat
    31681 tagccactgc atttgctaaa ggaactcctt tggttgcaac tgtcatcaca gcgtcaatct
    31741 tttctccttt aaaggcattg gcaataatac gaccaatatt ttgtaaaatt ttaggtgtac
    31801 tcagcaagtc tgacaaatag atatagcctc caggtaagat gcgatcattc tctgataacc
    31861 tttgacacag gtcttcaaca atggtacgcg cttctgtttc tgaaatactg ggggtaaaaa
    31921 ttacgcctcc acttgctcct gtaagtgtat cgatatcacc aatgttagct tcttcaaaag
    31981 ctttcttgat aatagcgata tcttctgaga tagaagattt tgcggcctca tatttagttg
    32041 caaaggtgtt taaactagtt aatttatacg gattgttaat caaataattt gaaatgacaa
    32101 ccatacgttc acttcgtctt aatttcatag tttccccatt tttatgtact ttttgctatt
    32161 ataccataaa gttaataaaa aacgaacatt cgattaggaa aatattggtt tttttgttct
    32221 tattaatatc atgcaagaat tcaatctaag ataaactaat caacattcct actgaaagga
    32281 cattctactt aataaccata acaagagcca aaaacactta tgaaaccatc ataagtgtta
    32341 agcacatcaa aaatcatcac aaaagcaaag gaactattac ttgagaaaca ctgatcaata
    32401 gtttggcttg taaaaagacc gattatccat ggcaaaaata cgattggtca tctcgccctc
    32461 gctaacacgg ctaagagctg ttgtcatcat catcatatta gcatcaatat tgtcaatcat
    32521 atgaataatt tcagcttcca tgatgcgtgg acgtaccgga ctaccgtatt ctaattgccc
    32581 gtgatggctt aaaatcacgt gcctaaggac aatgacttct tctttggtat catcgatttg
    32641 tagttctgaa attacttttg taatttcttc gttaatgagg gaaatatgcc caatcaagtt
    32701 accacgaacg gtgtattctg tattatctgg tcctgttaat tctatgactt tagctaagtc
    32761 atgtaacata atacctgcaa acagtagact cttatttaag tcaggataga tatctccaat
    32821 gctatctgct agtctgacca tcgtagcagt atggtaggcg agacctgact caaaagcatg
    32881 gtggtttgtt ttagctgcag gataagtata aaattcttta tcatacttac gataaagagc
    32941 ccttacaatt cgttgccacg ttgcattttc aattttaaag agcatctgtt ccaaatagtc
    33001 acgtacttct tcaacactga caggtgcctt ttctttgaag tcctttggat cattgggctc
    33061 ccctgggcga acatttcgca aggtgatttg attaacctga ggggtaccat tatagacctc
    33121 gcgtcgccct ttcataaaca cgactttacc agcagtaaat tcttccacat tataaggttg
    33181 ggcatcccac agatttcctg aaatctcgcc agtgtcatcc tgaaaggtaa ggctaataaa
    33241 atctttacca gctcttgtct tacgaacctc tgccgactta atgaggtaga acccttcaaa
    33301 aagctggtct tttttcattt gattaatttt cattattttc ctcttctaat aagggcatgt
    33361 tcaagagaga ttttgttgct tggtcttgat aagtttcaac ggtattcaag gctcgaacaa
    33421 tggcatttgt ccttgttgaa atgagctgat ccagcgtatt attagctgta ttcatttgtt
    33481 tttgagcctt ggcaagcagg ccgccaaatt tatcgaattc taacttgaca ttgcctaaaa
    33541 ttttactgat gtcatcagca tttttttgga tattaagggt cttgaaacca acagataagg
    33601 aattgagcaa agcagacagg gtcgaaggac ctgcaaccac aatattttct tcccgacgaa
    33661 ggctatcaaa gaaagccgca tttctgacca cttctgaata aagaccttct gttggtaaga
    33721 acataactcc gaaattggtc gtctctgggg ggttcaagta ctttttatga atgtctttgg
    33781 caaagcgttt gatagctgct agaagtgctt ttcggctagc ctcgatggcc agtttatcac
    33841 caacttcgta agcatcttct aatcggtaat aatcttcaag agggaatttt gagtcaatcg
    33901 gtaggtaaat atagccgcct tgaccatttc ctgggagctt aatcgcatat tctacgcgtt
    33961 cactagaacc actaaccgtt acaaattctc tttcgtactg gcttgatgtc atgatatcct
    34021 caatgatttg gcctagttga agttcgccta aaatgcctcg tgttttggta ttggacaaaa
    34081 ccttatttaa agtacccaca tcttgagcca cgctacgcat ttctcccaag cctttattga
    34141 cactttctag ttgcttggat acagaatcga aagaggcgtg cagacgattt tttaaggttt
    34201 cttccaattt ttcttcaacg atctggcgca tttcctccaa acgtttttcg ttagattctt
    34261 gcatattttt gagcgattgg ttgacctgct ggttaatttt ttctaagcgt ttgtcagacc
    34321 ggtccctact atcagacaaa ctacggtgca agacgtcacg aatatctgtt aattgttggt
    34381 aaaggtctgc ttgttgtcgg ttcatcagct gtgttagctc taacaattgt tgcttgttag
    34441 ctgtatccaa ctggtaggtc atttggtcag acaaattatc cgcgttgcct tctagggttt
    34501 gggcaagctg atgttgaagg ccgttgactt tgaacaacag ataagcccct aaacctaaga
    34561 gaaccaagac caaaaggaac aagataaggt ccatactaac tccaatcttt actttgaata
    34621 ataatcaagt agccacttgg caaactaact gtaataggtt gatggataaa ggcattactg
    34681 gaatagattt tctttttgaa aaaattatct tgcgtcaact caaatttagc accagtaatg
    34741 gtcaagtcag cttctccttc tgccataaat gccacatagg tcatcccttc ttcttgatgg
    34801 ataaggtgct gacctgccgg gcggtaggta atcatatttt gttggtcacg caaggcgatt
    34861 tgtgccataa agggagcaat accagggtcg ctaggcaaga aaatattgga taagaggtgg
    34921 tccattcgac ccccaaaagc cccaaaaatg gtcacttccg cctcagggaa acgtgcaaag
    34981 acctctttaa gagctaattc agtatccgta tcattttttt ctggatgagc agtaataaaa
    35041 agctctgcct tctcttttat atccgtaaat gcttcttggg aaaccgaatc aaaatcacca
    35101 acggccatat tcaaaggaag cccattttcc aataaaaaca ggctcccact atcaataccg
    35161 acaaaataat caaactcacg ggtgaaataa gaaagatctc ccccagaaaa gagggctact
    35221 ttagtcatgt agggccgtcc ttagagtctg cacttggctc actaggtcac tggccttgaa
    35281 aaggtaagaa cctgccacaa agacattggc ccctgcttca taacaagcac gaatggtctt
    35341 attgtctact ccgccatcaa cctcaatgtc aaaggacaat cctttttcat ctcgccattt
    35401 ggctacggta gccacttttt ctaaacattc tgggataaag gcctgacccc caaaacctgg
    35461 gttgactgtc ataatgagga cttggtcaac taagtctagc aaaggttcta gggctgttgc
    35521 aggagttcct ggattaatca ctacccctgc tttcatacca gctgccttga ttttttgaag
    35581 ggttccatga atatgacgag tactttctgt gtgaatggtc atgatatcag caccagcttg
    35641 tgcaaaagcc tcaacatagc gttcaggatc aaccaccatt agatggcaat caaagaccaa
    35701 tttactgtgc tttctcatac ttgccacaac atctgcacca aaactgatgt taggaacaaa
    35761 ttgaccatcc ataatgtcaa tgtgaacgta ttcggcatct gtttcttcaa tacgagctag
    35821 ctcagaagca aaattagcgt aatcagctgc tagaatagat ggggcaattt ttagagttga
    35881 catggagtag acctactttc ttttgataac ttttttatat gtttcacgac ggttttcaat
    35941 ttcactgaga aattgcaggt aatgctcata acgaactggc cacaactctc ccgtttcaag
    36001 cgctgccttg acagcacact tgggttcgtg ggtatgggta caggatctaa acttacactc
    36061 atggctcagc cggcgcagct ctggaaaagc ctcgttcaaa tcttcagcat tagcaatatc
    36121 atagtctaat gatgagaaac ctggcgtatc cgcgattttt ccgccatggg tattgtaaaa
    36181 actcacagct cgggtggtgt ggcgaccacg ccctagacta tctgagattt ctcctgtttc
    36241 aagagccaat tcgggggcga ttcggttgag aagggttgat ttcccaacac ctgtttgtcc
    36301 cataaagacg gtaattttat cagctagcaa aggcaacaat tcctcaagac tggtcacaaa
    36361 atcgtaaccg attgcctgat actgtcgacc aatagcctta atctcctcgg gactatctaa
    36421 taagtccatc ttagagatat aaaccactgg atgaatggct ttgtgttcaa gcaagatgag
    36481 aaagcggtct agaagattgc tgttaaattc tggttcttta gcagacataa taaccactgc
    36541 ttggtcaata ttgacgatag gaggtcttac caaactgttt ttacgaggat gaatcgctaa
    36601 aatataacct tcagagttgt cctctgctga gaaatccacg atatctccaa cataaggtgt
    36661 ctcaccgcgc ttcctaaaat taccacgcgc tcgcgtctga tatacctgtc cttctgactc
    36721 cacgtaataa aaaccagcca gagatttaat gattttacct tgcaactgtg ctcctttgcc
    36781 ctactataat aactctatta tatcagaaaa ccgctcccaa atcagcattt gactctaagt
    36841 ttcactcgcc ttaaaaaact gtcaagattc tctagaccac tggctatcat ttaggtcact
    36901 gctttttaaa aatagaatat tttatcaact aaaaatcaga tcactgatga ttttttgagg
    36961 taggaaacga tgtgaatttt aagaagacct ttgctattta cgaaaaagag tctaaccgta
    37021 ccgctatagt cacgctcttg ttaattgccc cttttttccg gggtattaaa aaactagctc
    37081 tgcactgcga taccttaacg gccagcttca ataagaaaaa tccccctgaa ctgaacattt
    37141 ctgttttgtc tacaagggaa tttttttatt gtcaccgggg gaaagctttt ataatccaac
    37201 ttcttttaaa gcatcagcta atttgccaaa atcttgaatc gacaaggcct caccacgaat
    37261 agaaggcttg atatctgcta gtgccagacc tttttcaagt ttagccttga tgtcttcaga
    37321 cttcccaaaa tggctagtca agttattcca cagggtcttg cgacgatgga caaaactaag
    37381 gcgagacact ctgaaaaaga aatcttcgtc cttaacctca atcaaaggct ggtcgcgacg
    37441 caccatttta aggatagcac tatcgacatt tggtgcaggt acaaagacag tgcgcggcac
    37501 aatgaaagca accttagcag tcatgtaata ctgcaccgca atggacaagg aaccataagc
    37561 tttagtgttt ggctcagccg agatacgatc tgccacttca cgctgcatca tgaccacaaa
    37621 ctcttggaat ggaattttgc tctcaatcaa gtgcatgaga ataggcgttg tgatgtagta
    37681 aggtagatta gccaccacct taatgggcaa atcaggattt ttaaactgct tgatttgggt
    37741 ctgcaaatca gcttttaaaa tatcttgatt gaccacttgc acattatcaa aatcgcgcaa
    37801 ggtatctgcc aaaatcggca ccaagcggtc atcaatctca aaagccatca cttcagcagc
    37861 attttctgcc aaaaattccg tcaaagcccc aattccagga ccaatctcga taacattgac
    37921 attctgatca atctcagccg tgtcaacgat tttctgtaaa atattggtat cggtcaaaaa
    37981 gttctgacca aaagatttct taaaggtaaa tccgtgacga tcaaggacag ccttggtcac
    38041 gctataatct gcaattctca tatattctct tctttttatg atcactttct tcttggcatt
    38101 tgaaccacta gcctaaactt ttttgccaag atacgccatt cagttaatgg ggctgtttta
    38161 ttttattgta ctctttactc ctcatatgtc tccatcactt cttccacttc tgctagggta
    38221 atgccaaata attcgaggcg cttgagcagt tgtttgccgt tggcatagcc gatgcggagc
    38281 ttttcgccca agtattccct gcgtttacgg ctatctgatg ccattaaaag ccctagacga
    38341 atcaggtctg tttgacgaat gtcaaaataa gactcatcat catattgctg agtgacatga
    38401 gcaagtgcct tttggaggtc ctcaaaattg gcatgttcaa cccctaagga acggccctta
    38461 ctcttagaac tcggaaccgc ctcgtttcgg tttaaaaagg cgtgacgagc tgttggcaca
    38521 gctgccataa tgagcttacg aatgcgctca ccattataat ctgggtctgt caaaacaatg
    38581 acaccacgca agtcatttag gcggttaatc cgttctaaat cttcttcagt gatagcagag
    38641 cctctggtct cataggtatc cacttcgtaa aaacggcgaa ggttagccgt gtcgtccttg
    38701 ccttctacaa caagaacctc ttgaatatta attttttcag tcaagcttaa ataccctctt
    38761 tgcattagca gtcgtttctt ttgcaacttc ttccacggtc attccccgta gctctgcgat
    38821 tttatcaacc acataacggg tataagctgt atgattttgt ttgccacgtt ttggaactgg
    38881 tgtaagataa ggggcatctg tttccaccaa aatcttatcc aaaggcaagt gctgcgctgc
    38941 ctcttgaata tcaagggcct ttttgaaagt gaccacacct gaaaaagaaa tcatcatgcc
    39001 aagttcaatg aaacgttcag ccatctctaa tgatcctgag taagaatgca tgatgcctcc
    39061 acgagggcca acaccagctg ctttgatgac ctcataggta tcttccaagg catcgcgggt
    39121 gtgcaccaca aaaggtaaat catggtcttt tgctaattgc atttggcgct taaaaacctc
    39181 tatttgcacc tctttggggt cctccatcca ataatagtct aagccaattt cacctaaggc
    39241 aatgactttg ggatgtgata attgagagac gatagactcc tcaactgctt cagaataaga
    39301 gcctgcttct gtcgggtgcc atccaatagt agcatacacg ttaggatact ggtctgcgag
    39361 agcaagtgct ccactaatag tggcctggtc aaagccaacc acattatggt aggccacgcc
    39421 catttcttga gccaaagtca attcttcagt ttcgtgtcct tgaaattctg ctacattcag
    39481 gtgcgtatgg gtatcaaaaa tagttagttt ttctacttta tttgtcatga tgttattata
    39541 acataaagat cttaaccaca tcagaaaact tggtgagaac ttctgccgtt taggttgatc
    39601 gtaaaaccct ttgctagctg acacttgtct attttctact tttttgacaa atgaccttta
    39661 atagtcggct cctacataag ccctcaaaaa tactacaacc tactcaaata aagtgggttg
    39721 aacaaatctg tatcacaaaa agggtcgcta ccttctgtta gcgatctatg ctatactagt
    39781 agatagttaa actgtaagga gtgtgctttg ctatgcctaa aaaccaccgc ctaattacta
    39841 aaatcgaagc atcattggaa catatgacca gtttagaaaa agggattgct cattttttta
    39901 ttacaaccga tctgacacct caagagttga ccgcatccga gatagttaag cgactacaca
    39961 tctctcaagc cgccttgact cgatttgcaa aaaagtgtgg ttttactggt tatcgtgctt
    40021 ttgcctttga ttaccttcac agtcttcaag aatcacaaga gactttccaa tctattcact
    40081 tagaattgac aaagcgcgtg ctgatggact acgatgctct tattaataaa acctatgagc
    40141 tcgttaatga ggaaaaatta ctgaacttag ccaagctgat cgatgcttct gagcgagtct
    40201 atttctttgg caaaggatct tctggactag tagcaagaga aatgaagcta cgctttatgc
    40261 gacttggttt aatctgtgat gcttattcag acactgatgg ttttacttgg gcaaatagcc
    40321 tcgtcaatga aaattgcctt gtttttggtt tttctttatc tggcaaaaca aactctgtca
    40381 tcacagcact tcatcaagct agtcagcgag gggccaaaac tgtcctctta acaacagata
    40441 atcaaaccga atttgacgac tccttagata ttattcccgt atcatcaacc caccaactac
    40501 attatgggaa tcgtgtgtca ccacaatttc ctcttcttat tatgatggac attatttatg
    40561 cttacgtttt agcgattgac aaaccgcaca aagaaaaaat cttcaaaaac actattattg
    40621 acaaagaaaa taacgacctt tagactacaa tagcaaaaag ggcgttgttt tctttttaaa
    40681 gggtcgtcat tcacctcccc cagtatactt aaacaagaac tcttcacgtc atatagactc
    40741 acagccacta agattagcta ctcgctaaat tattttcgat tttctcagga gttataaatg
    40801 aacaggatcg ctcattcttt tgtttaaaat ggtagtaagc tcctaatata ccagcattat
    40861 ttccatgact agcaaacttc agctgagttt tcttggcaag actagaaacc aagtagctat
    40921 caagagctgt ctttaattta tcagctaaat aatctttttg cgccatgata ccgccaccaa
    40981 gtaccaccac atttgggtta acaacgtagc agatattagc aataccttgt cctaagtaat
    41041 ccacctgctt actaatggct gctatacaaa tcgcatcacc cgctttagcc tgctcaaaaa
    41101 tacgacgacc atcccattgg ctaatgtcat ccccataagc taaggccacc tcttgaacaa
    41161 gagctgtggt agatgccaga tcctgaaact gaccatctga caaatgaagg taaccaactt
    41221 cgcaagctga atgactacta ccatgaaaaa cttgggaatt aaacaataaa cagccaccga
    41281 ttcccgtccc aattgtcaag caaagagcca caggataatc cttggcactg ccagaaatag
    41341 cttcggctag accagcacag ttaacatcgt tttccacttc acacggtaac ccgaaagtct
    41401 cttcaatctc ttttttaaac tgagttccag catagttagg aatctgaggg ccggcataaa
    41461 agatttctcc cttatcagga ttaaccattc ctgcagaaga aatggccact ccagccagat
    41521 ccatttggtc ttgataggtc tttaccaagc ccttgacctt ttccaaaata gagggaccac
    41581 ctttataagc ctcagtggcc atttcctctt tttccaacag gtctcctgtt tcagaaatca
    41641 agccatactt gatagcagta ccaccaatat caattgctaa ataatgcttc atttgttatc
    41701 ccctcgcatc ttattaaaag gtttccttag cctgattaat cagagcagca gcccgttggc
    41761 aaataaccct atcttcctcg accaactcag ctaaaggtga tcgaacagaa ccaatatcaa
    41821 gaccctcatt aatacgaagt acttccttaa taaccccata catattgccg tgagcagaaa
    41881 caaggacacc gataatctca ttaatagtat attgaagggt cttggccttt tctaaatcct
    41941 tgtcaactat aagttgattc agccttaaaa ataattctgg catagccccg taggtgccac
    42001 caatgcctgc agcagcaccc atcaagcgcc ctcctagaaa ttgttcatct gggccattaa
    42061 aaacaatatg atcgtctccg ccaatcgcac agaaggtttg aatatcctgc actggcatgg
    42121 atgaattttt aacgccaatc acgcgcttat tagccaacat agtcttataa aggcttgggg
    42181 tcaaggcaac ccctgccagt tgaggaatat tatagatgat aaaatctgtg tgaggagcag
    42241 ccgaagaaat cgcattccaa taatcagcaa ctgcatattc tggtaaccgg aaataaatag
    42301 gcggaatagc tgcaatggca tccacgccca aacgttctga atgagctgcc aattcaatac
    42361 tatctttagt gttgttgcag gcaacgtgat taataatcgt cagcttgccc ttagcgactg
    42421 ccatgacatt ttctaacacc aattgacggt caaaaacgct ctggtaaata cactctccag
    42481 aagagccatt aatgtaaagc ccctgaaccc ctttgtcaat atagtactgg gtcaaggcac
    42541 gcacacgctc agggctaata gctccttggt catcgtaaca agcataaaag gcaggaataa
    42601 tgccttggta tttcgtaaga tctgtcatag taatgtcctt tattcaatgt cattattaag
    42661 tgggaatcgc ctaagaaggg attccatgat aatcaagtag aggtaagtta ggctactgat
    42721 gccgatgata gctagcaaag acacgcctcc aaataacgtt aacagagaca attgtaggct
    42781 aaatatcgtg agacaaataa gagccaagaa agcaaaactc catggaaaaa agagtccggc
    42841 tagtaaaaag cttcgcttaa acagcgtaga tagggaaagc tcttttctga cggcctgagg
    42901 ataagcgtac aaaaagagta taactaccag aaataaaaca gcaatgcaaa gtactttaaa
    42961 cccttgaaaa actaggcctg attggtttcg aattaagaaa agatctaaga cacaaatact
    43021 cattatcaaa agctcaataa gacctaggcg catccctctt ttaaaataat gtttaaaata
    43081 agagctataa gtagtaaaaa gctgactaac ttgaccttct cgccaatcca acaaactcgc
    43141 atacaaagcc attttagcaa ccccaatcgt tagaagggga aggcaggaca agacaaataa
    43201 gagattaaac acgagcaaat caaacagtgc tgcgctagcc ctcatccatt tactatcaag
    43261 cttgaagaga gagtgtaaaa gtccctgttt tttcgatgtc aaatcacaac ttcctttcta
    43321 gaaatacgct tacaaacaaa agctaattcc cctcttaaac gtttaacaca tgacttgctt
    43381 cccttttgac ttatctatct atgcacctaa attaagaggc aacctataga ttaagcttag
    43441 tgacacgctt tatttagtct aacctttcac agcacccata gtaatgcctt gggtaaatga
    43501 tttttggaaa acaagaaaga ccgttacaat aggcactgca gccatggcag cccctgccat
    43561 aatcaagcca taattagtag ccatttcagc ttgcatagtg gcaaccccaa gtgaaatcgt
    43621 taaattttcc cgagaggtta acatcaccaa ctgcataaaa taatcgttcc aagtattgat
    43681 aaaggtaaaa atcgctagcg ctgcaaagcc tggtttgaca atagggaaag ccacattgaa
    43741 aaaggtacga atttcgccac atccatcaat cttagcggat tccaataact cggttggaat
    43801 attttctgag aactgtttca taaggaaaac accaaatggc cagcccacaa gaggcaaaat
    43861 aacagccgcc aaagtatcat ggattccaat aaaattaaca atccgcacaa gaggcactag
    43921 aacaacctgt tttggcaagg ccatagcagc aataaaaatc gaaaacaaaa tccattgtcc
    43981 ataaaaccgc tttttggcca aggcatagcc agccaaagag gaagtgccac aaaccaagaa
    44041 catggtcgcc accgaaataa agacactatt ccacaaccat tttaaggctg gattttgcac
    44101 taccaaggcc ttaaaatttt caatagtagg tgcctttggc caccattgcg gtggaatcat
    44161 aatggtatcg gcttgagcct taaatgctcc tgtcataatc caataaaatg ggaaaataaa
    44221 caaaatggtc aagatgcata gaataacagt agtcagaaca tccgatgcgg ttagtttctt
    44281 tttcgtcatc ttaatatcct cctaatattc cacatcatta cctaaaattt taaattgagc
    44341 aaagctgatg attgcaatca tgactgccaa gaacacaccc attgtgttgg catagccgta
    44401 ttcagagagc ttaaaggctt tttcatacaa atagtacatg agggtactag ttgaataatt
    44461 tggccctcca gacgtcaaga gttgaatcaa agcaaaacat tggaaggaat taatggttgt
    44521 tatgacagca atatataagg ttgttggcag gagacttggc cacttgatat tccaaaacac
    44581 ctgaaattct gtggcgccgt ctacacgcgc agcttccatc aaagaattat caatatttcc
    44641 catagcagca atatatagaa taataggctg cccaacagat gtggttaata aaatagcaat
    44701 aatagctaac aaagcccagt gcttatctcc cagccaacta atgttttgtt caatcacatg
    44761 agcatatttt aagacataat tcaaaatccc tgacatcgga tcatagatcc atttccaaac
    44821 caccgtcacc gcaacacttc cggtaacaac aggcagaaag aaaactgccc ggtaaaacga
    44881 acgcgccact acatttttgt cgtaggtttt agccgccaca aagagggaaa agaaaactac
    44941 aacaggtacc gaaccaataa caataatcaa ggtgttcata agagacttca tgaaaatggg
    45001 atcttgaaac atcctagcat aattagcaaa accaacaaag gtaaaatccg tcatggaata
    45061 attgaaaaaa ctcgtcacaa agcccataat catcggtatc aagacaaaaa tcacaaagaa
    45121 aaccaagacc ggagctaaga aagcgtatga gatgagcgtc tctctcattt ttaatttatt
    45181 gacgttcact tgaaatacct ctttttctat taatctctcc taaaaaagga aaggctcctt
    45241 tccagtgacc atttgacatg tgccgtgaaa agaagccact tgttctgaac acttattgtg
    45301 tttttttgat tgtcttgttt gctttttcag tgaaggcttt caaagcatct tctggctttt
    45361 catcaccatt agagatggct tgaaccattg ggaaccaaag agttctcatt tcagcaaacc
    45421 catcaatcgt gttgtagtat ggtgagtaga attttgtcca ttcagcaatt ttttccattc
    45481 gtttgtcttt gtaaagatcc ccataagaag ttcttacagg gaaagcacct gtacgaacaa
    45541 catttttagg tccccattct ttatcatcag cgataaattg gataaatgtc ttagaggcag
    45601 cgactttttg ttcatctttg ttattaaaga ccgcaaaacc atttacgagg tattctagtt
    45661 ctggtttgcc atcatctgat gggaatggga tttcaaggta atccacttta ctagcttcta
    45721 acaatttagc ttggatgccg ggttgtgcag gcgcccaaag aatggtaaag gaagtttggc
    45781 cattcgcaaa gttttgaata tcagctgaac cgtcgtattg agagccattc atcattaaac
    45841 catctttaat ccaattggaa attttagtca tggctttaat agagttagca tcatctgtgg
    45901 tgtatttggt tactttgtca tcggtaatat gactactata aaggttagca aagaaggcac
    45961 gtggtccttg gtcaccacct tgaccattag caaagaaaga acctgggtta tatcctttgt
    46021 ccttcaatgc tttcaagact ttttcaaaat catctgttgt ccacccctct ttcacaaggt
    46081 caaggacgcc agcatctttg agcatttttt tattcaacgc catgtagaat ggagcagagc
    46141 tgataggata catgtaagct gtatctcctg cttttgaggc ttgaatcaat ttgtcattgt
    46201 taacatcttt ggtaaactct tttgtgaaca agtcattcaa gtcagccaat ttcccatttt
    46261 taccatattg aatgatacga cctggagcat caaagaggac atcaggagct gttccagctt
    46321 caatagcagt tgtgattttc tcaggaccag atgtaaaatc aatggtttcc aattttacct
    46381 tgatttctgg attagctttc tcaaaggcag caatcaattt cttctcatag gttcccacac
    46441 catcttcagc tttttcttgc gtgaagaccg ggaaagccca ccatgtgatt tctgtcttag
    46501 cagtatcaga tttacttgca ccagcctctt tctggctctt tccgccacaa gctgctagtc
    46561 ctaaaacaga tgcaccaagc atcactaatg aagctaactt cttcatgttc atcgtaaaat
    46621 ctcctttttt tgatgtgtgt ttctagtttg acaaccacta ttaggatttg agcgcttcga
    46681 taaaacgctc tgcaatttcc ttaggccttg taatggcccc tccaacaaca atacctgcca
    46741 cacctaagtc attaattttc ttggcttctt ctggggaatg aatctttcct tcggcaatga
    46801 cagcaatgcc tgctttgcaa agagcttcta tcaatgccac atcaggacct gcttcctgac
    46861 ggctatacgg ggtgtagcct gacaaggtgg ttccaacaaa atcaatgcca gcctgatggg
    46921 ccactagtcc ttcatcaaag gtactaatat ctgccatcaa aagctgattg gggtactttt
    46981 ccttaacttg tcgaataaag ctagcaatat ccaagccatc atgtcggtca cgcttggtac
    47041 aatccatagc aatcactgca atatttaagg cagctaattg atccacttcg gccatcgttg
    47101 ccgtaataaa aggctcttgc ggcgggtaat cttttttgat gataccgata attggtaggt
    47161 ctgttatggc ttgaatttct ttaatgtctc taaccgaatt agctctgatg ccgacagcac
    47221 cagcttcttg agcagctttt gccagcagtg gcataatacc cccagtctct gaatagagag
    47281 gctcacctgg caaagcctga caagaaacga taatcccacc ctttaactgc tccatgagct
    47341 tttctttggt tggtttatca ggcatagttt ctactccttg tgtttcttag ttttaataaa
    47401 aataacgttc acaaagttat tataacaaaa aataaagcgc tttcaatagc aatgagactt
    47461 ttagaatcta ctttcatttt ttatattatt ttctattatt tggaatgctc tttcatacaa
    47521 caaataaaaa ggtaaggagt tgacaccata cttatacatt gcaaatttcc gattagaaaa
    47581 cgttaaaaaa ccaagagcct cgagcactct tggtttactt tagttgtatt ttttgcaatt
    47641 aagctgataa tactttacgt cctttacgac gacgtgcagc aagcacgcga cgtccgtttt
    47701 tagttgacat acggtgacgg aatccgtgtt tacgttgacg acggatttta cttggttgat
    47761 aagtacgttt cacagtgaat acctcctcat agattttgta ttcgtttagc cggctatttg
    47821 tgatatcagt tactaaacat actataatat tctatcttaa agagggtcta ctgtcaagat
    47881 ttattttcgt ttttcaacag tttctctctc atttaagagg ccgctcattt cataaagtgt
    47941 ctcttctttg acactgttcc tttgccttac cgttgaaacc ttatcaatag caacaataat
    48001 caatgagatc agtaaaacaa acggttaagc tggccataca aaaaatcttc gatagctaaa
    48061 ctaactacca aagattcttt taggatctaa cgttgaagac tgactaccac atagcggtta
    48121 gggtcattgc cttcagaata actatcaacc ccttcaatgg atgaaacggt tttatgaacg
    48181 attttacgct cactgttact catgggatcc atggtgtaat cttggccaga ttccaagacg
    48241 cgtttggcaa ctttttgcgt aaagtcaatc aaggtttctg ttcgatgttc cacataatca
    48301 tggacattca aggatactga aaaatttttt gaatagcggt cgtgcaagaa gttttgcgcc
    48361 aacaactgca aggatttcaa aaccttacca tggtaaccaa tcacacgtcc cgcctctggc
    48421 gtttcaatct gcaaattgat ttggcgacga ttgttgctgg tttcaacggt ggcttcgata
    48481 tccatttcat agatgatttt agtcacataa tcggacactt cctgagcagc tttttcaata
    48541 tctttgctga aaccatcatt accaggatct tggggcactt ctgattcctc gactgggatt
    48601 gacggttgtt gtacttttct ttcagtgact gtctcagcaa gattagaagg ggtttgcgct
    48661 ggactatctt cagacatgag aggaaccact ttggtatctt ctgcttctaa cttttgagtg
    48721 gcttttattt cttcaggttc tacatcagca gaattgaccg cgggagcatt tttttgatta
    48781 atatcctctg gaacacctcg agtggctttt ttatcagcct tataaaccgt cttgtcgctg
    48841 ataccttcga tatcaacttg ggctggcttt ttaccgaacc cgaggaaacc ttttttctct
    48901 tttgaaatga ctttgatatg cgctttaagg cgtgataacc ctaactcttg aagtcctgtt
    48961 tcgatagctt cttcgactgt ttttcctgta aataatacca taacctaaac tcctattttc
    49021 tcttcattgc ttttttacga gcacgacgtt cacgaagacg gcgttctttt tcttcattgg
    49081 caagacgctg tctttcggca ataatcttaa aaggattgtt taataacagt agttgtacca
    49141 cttgaaaggc atttgagacc gtccaataga gcactactcc actagccaag ttaaagccca
    49201 tgaaaaagat cattagcggc atcacataaa tcataacagt catcatgaca tttttttctt
    49261 tagccgctag attggtcaac caagtggaca agaaagtgaa gacagctgcc aaaactggta
    49321 aaaggtacaa atgatcatgt tgtgccaatt ccacccacaa gaaagtccct gtttttaaga
    49381 aagatacccg tgtcaaggct tggaataagg caatcataac tggcatctga attaagaggg
    49441 gtaagagact ggcataaggg ttaaccccat attttttgta aagggcttga ctttcttcag
    49501 ccaacttcat ccgcgtttgt gtgtctttac cagcgtattt cttttgcaat tctctaagct
    49561 caggttggat gtcttgcatc ttctggcttg atttgatttg catattaaac aaaggcatga
    49621 gcatgagacg gatagtaagg gtaaaaagaa taatgccaac accaattgaa ccatcaaagg
    49681 aaagccattg aattgctctg gcaaataagt aaaccaactg gtcccaacca ctagatgatt
    49741 gtgccgttac ctcaccacga ccacaggcca ctaataatag aactaagggg actattcttg
    49801 caattttaat gtttttcttc actctcaaaa cctttctcaa gcaattgtgc taactttaaa
    49861 acatgatgta aattttgttg aagctcttga tactccaaag actcgacacc cttacgggca
    49921 atcaccacga aatcctctga cttcagctga taccctaatg ccatgataac atgacgtatc
    49981 tttcgtttga ctgcatttct ggtgactgca tttcctattt ttttaccgac agaaataccc
    50041 acacggaaat ggtcttggcc tctatttaaa tgataaatga caaattttcg atttgctgta
    50101 ctttttccat ccttaaatat ggcttggaaa tctttctcac acttgacacg ataggtcttc
    50161 ttcaaaattt aactccataa tctaaattat taccattata ccacatcccc taaaaaatta
    50221 aaaagcccta accctttcag attaagcctc tttctgtact atttctagtt tttgtgcttc
    50281 aactgcctct tgtcactcca tcttttcgta gtatagttct tctttcgaca aaggaataac
    50341 cttcagaaaa caaccataaa aagtcagaat ccacaagacg tcagctactt atccctgtat
    50401 ttacctatca aaaagcccgg caagccgggc tttaatactg attttacaat cagctaatgt
    50461 gatatccaaa caaagacaac tgacatcgtc attctgtctg ccgagccatc atatcaaaaa
    50521 tactatttgt ttatggagag agagaaaaca atattttgat tgaattgggg attgattgct
    50581 cgataaactc atgacttcgt aaatctttat ttacattaat tattatagcg aaaaatactt
    50641 caataagagc atcatttcct gaaatgttgc tttttcgtcc taaaatgtta ttgctctctt
    50701 aactttagcg aagagcctcc caccgttcaa acagacattt catttttaat cgtgatacca
    50761 tacaagaatc accattttcg aaataaagga gctgcttact cttatcaatt cgaacaacct
    50821 tatctagatt cacaaggtag gatctatggc acaaaaaaag tttcggtgct actgcttgaa
    50881 tctcagatag attaccataa aactctaatc tttctgtctg agtccataaa caaactttgt
    50941 gaggagttgt ggctgtagca aagtataaaa tatccttata aggcaatttt aatcttgtct
    51001 gtggagtctc aaataaaaac atgtcctttg actcacgact agacatcata tcgtaagtat
    51061 atcggataca ttcttcgatt tgttctttaa actgtttttg accacctgct ttatcaataa
    51121 aatctagagc agatacctta tatttaaaag aaataggagc aaattctgaa tgagtggtga
    51181 caaacacaat aacggcatta ggatcttttt gtcgaatagc tgcagctaat tcaagcccac
    51241 aacgagtata ttcaccaatt tcaatatcta aaaaatacag ctgatggtct cctctttctt
    51301 ggatactctc aaataatttt tgaggagtcg agaacacttc aagctgatta catggtattc
    51361 tagtctcttt taagatacct actacgatag attctatgcg tgtctgctgg ataaaatcgt
    51421 cctcaagaat aaaaatgttc atcatacttt atctcatttc taacaattgt cttaatcgat
    51481 aatggtcact tttagtcgaa agcgttattt gggggtaact atctaaaaca gtcaaaaagt
    51541 gggctgagtt ctgctgctga gcatcaaagc gtttggctat atccacacga ttggtttttg
    51601 tgctattttc aataataaat aattgcttgt tatcttgttt aaagtatgca atagataaaa
    51661 aaggacgtct actgcctttg gctgtctcaa tagcattgtc cactagtcca gtaaaaagta
    51721 caattaaatc gattaactta ataggtaaat gatcgataac atctggaatc tcaatataaa
    51781 gttcaatacc caaatactga gcttcaagca atttggaatt catgatgctg cgaatcacag
    51841 cctctttgat attgtctaaa gaagatattt cataatttgt gcgcatcata gaagttgccg
    51901 attgctgaat aaccgtgtca taaactctag taatcagatc tatatcacca ctatcgatac
    51961 tatcttttaa actaattaaa atattttcag aatcatgttt aactgttctg atttctcggt
    52021 aaagttgctc aatcgattga ttgtaatttt caagatacgc aatacgttca ttttgtgctt
    52081 gtgttaattt ttgtgacagc tgatctttag caaatcgatc taatttcaca ataacccaaa
    52141 taaaaatagc taaataaata aatactaaaa tagaccggta ctggaaatat agtgcaagaa
    52201 atccgctttg cacagttacc aaaaaatggg cgaaaaagta gtaagaaaac atggcagtat
    52261 tcatccaaaa tacccacttt ttcatcttat cttcactgat aaaccttatt aagcttaagt
    52321 caatactgaa aatgtagcta aacagataaa atattggtaa tacaaaaaga taacataact
    52381 ctaaaagctt aaggttatta ttaatttgac caatgctaaa tcctaagaca gctggtaaaa
    52441 agaaagatcc gatgacgcga aacagtaatt cgacaatcaa gatagtaaag aaaccattaa
    52501 acatatgctc aaataatttc tttttcggag cacttaacaa actaacaata ataaaaaaca
    52561 gttggtcaat caaaatgact ttgtcaaata tcatattagc aattacaaaa ctaatgccta
    52621 taacgctaac ccgtttccag cttagtttaa tagcagaaac ctttgcaaaa atgacccagc
    52681 tgttaataaa gatagtagca tagaataaag ccatactgta tataaccatc atctatccac
    52741 ctcctccttt ggcatggtca aggtttggct aaattcctta tcaaaacttt tagtccgcaa
    52801 ggataaataa ggatactttt tgagaatacg ctgcgcatta gaaaggccga taccacgttc
    52861 tgaacctttt gaagaatagc cttcttcaaa gatcttgtta atgtctacct tttttttagt
    52921 cgtatttgtc acaacaaaca tctgatagtc atctaacaaa aagtaagcaa ttgacatatg
    52981 aggttgctgt gcttcaagag ccgcctcaat ggcgttatca caaaaaatag acatcaacaa
    53041 tagtaagtcc aactcaggaa tgtaagtctc ttttatatta tctggcactt ccacattcaa
    53101 atcaatacct gatttttccg cactgataat tttagctgac aataagctct taatcgatga
    53161 gatattaatt ttcctaagct tcgagatatt atagtgttta tcatcccagt agtcgttagc
    53221 ttcatgaacc gtttgggcat aaatatcttg aatctgagta atggattcac tcttaatggc
    53281 ttgacctaaa cgctctatac ggctcaggta atcactttga aaagctctta catctcgata
    53341 gagtttctca agatgtttcc cataagtctc taagttagtc atataagctt gttgttctct
    53401 tctcaactca tttttaaggt attctttaga actatgatta aaataagata gaagataaac
    53461 taaaagaagt ataaacatca aaaacaataa cttataaggt gtgggaacaa aaagagaatg
    53521 atgaaaatgt aaaaaggggt ccgtaaatcc taaaatgaca aaaatgtcca cataataaac
    53581 caaaacaaaa atcagcaatg tttgatagaa attatgcgat cgtttcgaat atccggattg
    53641 gcatatcatc ttgtaatctt ttccaatcat ataattaata atagcaaaac ttggaaaaat
    53701 cagcagataa gcaagcaagt caaagataat atgacccaga taaataccac tcgacaaaaa
    53761 aagatagggg ataacgattg tacccataaa tcgagatagc aaatccacca aaacactagg
    53821 tgcaacagcc aaaaaaagag ctttcaaaga aaataattgc ttggtttctt gccttaaaac
    53881 aactaaaaat aatagaggat caattaacaa tggcgacaaa tacgggaact gattgaaaaa
    53941 tagggctaaa gccaaaatcg ttagttgttt ccaaactggt aatgtgatat cagatagaaa
    54001 ggaaaaaata taaatttttg tcatataata gacaataatt gataataata aaaacatata
    54061 ttcgctatta gccatttttt tctcctttcc aactttatta ttttagcata ttttatgaca
    54121 atgattacaa tattatttga ttacaattga ttagctaagt gagtactaaa ctagtctctt
    54181 tcagcatata ccaaaaaaat attgtacact aattgattca taaaaaccat ttctttaaat
    54241 cacactaatc aaaacctcac cgtttgctgt cattatcacg taagcatctc accacctctc
    54301 tttcaaatcc aatctccaaa atagaaataa actatactat tttttacttt accaaggtag
    54361 caagctcaga taacgataaa aaagactgaa gaacttaatc ttcaatcttt cgttgtcgtg
    54421 actttttaac tccttaaagc gtttaaaaat aaaggtgaac gatacagcct tatagcatgt
    54481 ttttgatgtg ctcaatggat ttatcacgtc ccaataaata aatcgtattt ggtaattctg
    54541 ggccatgcat ttcaccagat actgcaatac gaataggcat aaagaggttt tttcctttga
    54601 ttcctgtttc tttttgaaca gccttaattt gtgggaaaat attttctggt ttgaagtctt
    54661 catctgacat agcttccaac ttagccttga aagcttgcaa gactgtcgaa actgtttcac
    54721 ctgccatcac ttctttttcg gcttctgtta attcagggaa atcagaaaag aaaaggtcag
    54781 tcaatggaat aatctcatct gcagatttta attgaggttt gtataattct actagcttct
    54841 cagctttttc tgtcaaacgg cctgcctctt caaggaaagg tttgcagagg gcataaactg
    54901 tttcaaaatc cgcatgttta agatactcat tgctcatcca atccattttc ttctggtcaa
    54961 aggcagctgg cgacttgcta aggcgatttt catcaaaaag ggcaatcagt tgctcacgag
    55021 agaagatttc ctcttctccg ccaggattcc agccaagaag ggcgatgaag ttaaagacag
    55081 cttcaggcat ataacctttt ttgcggtaat cttcaatgaa ttggagggta ttggtgtcgc
    55141 gttttgataa ttttttaccc gtttcagaat tgatgataag agtcatatga ccaaactctg
    55201 gcgcttccca gccaagagct tcatagacca tcaattgttt tggcgtattg gcaatatggt
    55261 catcgccacg gataacgtga gaaatttgca tatcatgatc atcaacaaca acggcaaagt
    55321 tataagttgg gtacccatct ttcttttgaa taacccagtc accaccgatg ttaccacctt
    55381 caaactcgat atcgccttta accatgtcag tccatttgta aataccggac tcattaacag
    55441 caagacggac tgttggaacg atacctgctg cttcacgctc agcaatgtac ttagcttttt
    55501 cgtcagctga cataccaata aattcattga tatagcgagg cgtttcgcca gctgcttctt
    55561 ggcgttcacg ctctgctgcc aattcttcct cagtcacgta agacttatag gcttttcctt
    55621 cagctaacaa ttgatcaata tattgttgat aaagtgctag acgttcagac tggcggtaat
    55681 tttcatgcgt ttctgggctt tcatcccaat ccattcctaa ccattttagg ttttcaagtt
    55741 gagaacgttc accatcttca acatgacgtt tacggtcagt atcttcaata cgaatgataa
    55801 aagtacctcc gtgacgacgg gcataaaggt aattaaatag ggctgtgcgg gcattcccga
    55861 tatgtaaaag ccctgttgga cttggtgcat aacgcacacg aattggttta gacatgcttc
    55921 ttctcctgtt acatatatca ctcagaaacc tgtggcacga aaaacaagca acaaatgatg
    55981 atttgagctt gccaagacct tttcagactt cttctaaaat ctttcttatt atagcatatt
    56041 ttacttgctt aggcgaaaaa aatcagccct aaaaagctga ttttatgtta ttttgactaa
    56101 tttgaactag ttggtagata acgtttaaga gtcccagcaa attgctcaag gttaagactt
    56161 tggatataaa tctcaccatg acctctaaag gtattaacaa ctccttcacc tgtaccaatt
    56221 gactgcataa agccattttc taaatgaata tcataatcaa gttctctgct ccatgctaca
    56281 acatgggcat tatcaatagt cattgtgcca ccatcaagtg tgattttctt gatagatcca
    56341 aacgagttag caagtaaggt acccaagcct tcagttgtca tgacaaaaag tccgccttga
    56401 ccaccaaaaa gtgcttttcc aatattttga cgttccattt tgtactgtgc tgaaccatct
    56461 agggctagaa aggcaccatc atttagacga tattgttttt cacctagttc taaagcaata
    56521 atctgtcctg gtgtattggg tgctaatgct aatttaccat ctccatttga catagcttgt
    56581 gtaatgaaca ttgattcacc agaaaccatg gaacggccga tggctccaac taattttcct
    56641 aaaccagatc ccttaccatt caatttggta ttcaaggtta cattctcagt atgataaacc
    56701 atacttcctt gttgtaagta aactgatccc ccatgtccca gatcaatctc aactagtgga
    56761 aattgcatgt tttgatcaat cgtaaatctc attctattgt cgaccatctt actctccttg
    56821 tttgtatgaa taacttgata caattattat aacgcttccc tatttctttg tctaatattt
    56881 tcaataattt ttaaaaataa aaaagagctg aattcagctc tacaacttgg ctactaacta
    56941 ttccattact tgtgtcatct ttccagtatc cacatcgtag acggcaccgt taataacgac
    57001 atcatcagag ataagagagg aggctcttat cttagtcata tcctcgcgga cactgtcttc
    57061 cacatcttgg aagggaagga aatcttgccc tgaaacatcc atacctaagt gctcatgaat
    57121 atgcttggca aagccttcat tagtaaaagt ctgcgcgcca caatctgtat ggtggagaac
    57181 cacaatctct cgcgttccca tttgctgctg agaaataacc agcgaccgaa tcatgtcttc
    57241 ggtgacacgt ccgccagcat tccttaaaat atgagcatct cctagagcca gccccagagc
    57301 ttgggccaca tgtagccgtg aatccataca agtcacaatc gctactttag tcttgggttt
    57361 taagggcaaa tgagctgtcc catgcaaggc cacataagcc tgattggcag ccataaaatg
    57421 ttcaaaataa gacatcaata aactcctttt gagaaacagc agagctattt ttgctgttag
    57481 tttgtcttat cttaacatct tttatggaaa atagctggat taacctctta gacggtcggt
    57541 atcgttcgaa aagttaaaaa aacaaatgat tgggatactt tcttgacaaa tttcctcctc
    57601 atttgctctt agtttatgat cctctagcta aaaactgcct ttaaaacctg accaaccgta
    57661 gtcactccga caacctcaat accttgaggg atatcaatgc cttgcaaggc atttttagga
    57721 gcatagacct tggtaaatcc aagctttgct gcttcattaa tccgttgctc aatacgggtc
    57781 actcgccgaa tctcacctgt taacccgatc tcgcctaaga aagcttcttg agggctggtt
    57841 ggtttttcct tataactgga tgcgatagcc acagcgactg ccaaatcaat ggcaggttcg
    57901 tctagtttga caccaccagc cgacttgagg taggcatctt gattttgtaa gagtaaacca
    57961 cagcgctttt ctaaaactgc cattattagg cttacgcgat tgaaatcaag tcccgtagtg
    58021 gttcgtctgg cattgccaaa aacggttggt gtcactaaag attgcacctc tgctaagata
    58081 ggacgacttc cttccatcgt tacaacgaca gccgatcctg ttgccccatc taagcgttcc
    58141 tctaaaaaga cttgactagg atttaagacc tctaccaagc cgccagactg catttcaaag
    58201 atgccaatct cgttagtgga gccaaagcgg tttttcacag cccgaagaat gcgaaaggtg
    58261 tgatgccttt ccccttcaaa gtagagaacg gtatccacca tgtgttctaa catacgaggc
    58321 ccagccaagg ttccttcctt ggtgacatga cccacaataa aggttgcaat gttgttcgtc
    58381 tttgcaagct gcatcaattc tgcagtgact tctctcacct gactgactga tccttgaaca
    58441 cctgtaatat cagggctcat gatggtctga atggagtcaa taattaaaaa atctggttta
    58501 atattttcaa tttctgtgcg aatagcttgc atattggttt cggcatagag gtaaaattca
    58561 ttgtcaatat cacccagacg ctcactccgc agtttaatct gctctgctga ttcttcccca
    58621 gacgcataga gaaccgttcc cttattagcg agctgcgtag atacctgcaa gagtaaggtg
    58681 gattttccaa tacctggatc accaccaatt aaaatcaagc ttccaggaac cacaccccct
    58741 ccaagaactc tattaaattc agacatgtca gtctgtgttc tgtgataact aatattatcc
    58801 acatctttta gtttaaccgg tctggacttt tctccagcta gactaacacg ggcatttttg
    58861 acttctttga cctctacttc ttccacaaaa gaagaccagg ccgagcaatt tggacagcgc
    58921 cctaaatact ttggcgactg gtagccacac tcctgacaga taaaggttgc ttttttcttt
    58981 gccatagtaa tctccctccc ctagacaaga caaacccact cttaaagaat aggtctgctg
    59041 tcataagcat ttttgttaaa tcgctttact gccctgtcga accaaaacca cctgttcgtt
    59101 cacctctggc ttggtcacca tcagcaatta aaaaaggcat aaaaaccccc tgaacgatcc
    59161 tctcacccac agctaatgtc acagggtgat ctgtaatgtt ttgcatttgt gcaaaaatat
    59221 gtccttcatt agcctcattt ccataataat ctgcatcaat cacacctact gaattaatca
    59281 ggataatccc tttttttcgt ggatttgacg aacgatcata gaggtaaagc acctcaccat
    59341 cttgcatata ggccttaacc cctgttggta ccaacttaat ctcccctggg gcaatggtta
    59401 cagcctcagc aacagacagg tcataaccag ctgcatgagt cgtctcacgt tttggtagta
    59461 aatcaggatt agtaaagctt gaaacaagct cgaaaccacg aatttttgtc attatgatag
    59521 gtatatcctt tcaagtcaat catatcctct tattatagac tattcgtaaa agaatagcaa
    59581 aaaagcggtc aactttaaac ggaccacttt taatcatgcc atcacatctc atccccacga
    59641 taactaaagc ggatgtgggt gaaatcatta tccaaatcct tgtctgccat aaaagctttg
    59701 gcatcttttt tcacttgaac caagtcaata ccttgcattt tggcagcata gacacagcca
    59761 caatagcatt gacggtaaat atcatactcc tcacacattt caacggatct gcgataaccg
    59821 ttgtttttct tgaaatcact tggcaggtat ttggtggtgt aaaccttttg cacatcgatg
    59881 cccacatcat taatggtttg cgaattttta tgaggactga tggttagggc actggcaaag
    59941 tagtcaaaac ctagttccac tgctttttga gcggtcttgt ctagtcggta atcaaaacag
    60001 acacggcaac ggtccccacc ttctggttcc tcttctaagc ctcgcacttg tcgaacgtac
    60061 tcattgggga catagtccgc ttcgagaaac tgaacagtat tgcctgtttt agcgttgaac
    60121 tcggagacaa actgttgtgt cacataggct ctgcgatggt attcgtcctt agggtgaata
    60181 ttagaattgg caaagtaaac cgtaatgtca gcaaactgcg tcaggtattc tagggtgtaa
    60241 gtggagcatg gggcgcagca gacatgcatt aaaatactgg gacgcacgga ttccttctcc
    60301 cagaccttgg ccatctgttg catgaccctg tcataattta tcttttgatt gggattcatg
    60361 ttagcgagaa tctcttgtaa atcaatcatt gtggctactt tctaattgtt ttttctcttg
    60421 cttgctatta taccatatca ggaaagaaag cttgactgct ttattgttca ccaaaaaact
    60481 ccgctaagac gcggagctga taccatctat tcaaagacaa attgattgtg atacaattcg
    60541 gcataaaagc ctttttgatg caatagctca tgatgatttc cttgctcaat gaccttgcca
    60601 tctttcaaca caataatgtg atctgcattt aaaatggttt tgaggcggtg agcaatgaca
    60661 aagctagttc gacctgccac gatagcttcc atagcccgtt gaattttact ttcggtaacc
    60721 gtatcaacat ttgaagtggc ctcatccaaa atcaacactt cagggtcagt cagtagcgtc
    60781 ctagcaatag aaatcaactg cttttgacct gttgaaaaga cattgtcatc atctgagaca
    60841 taggtattgt acccttttgg taaggacatg ataaagtcat gaatatgggt cgcacgcgca
    60901 gcagtttcaa ccatgtcttg actaatggtc tgatcaccaa aacgaatatt atccgtaatg
    60961 gttcctgaaa aaagaactga ctcttgcaac acaatcccta ccttttgacg aagactatcc
    61021 aaatcgtagt cacgaatatc acggccatca aaggtaatcg aacctgcatc cacatcgtag
    61081 aaacggttaa tcaagttcat aatagtggtc tttccagaac ctgtcggtcc aaccacggca
    61141 atcattttgc ccttgggtgc aacgattgac acatctgata aaactttttg cccaggaaga
    61201 tacccaaaat cgacgtggtt aatcgccact gcttctttta agctggtgaa cgctggtgca
    61261 ttttgtggac gaacttcttc ggtttcatca aacatttctt gaatacggtg agcaccggta
    61321 aaggccagct gcaattctcc ccaactagac gcgatttgca tcatgggttg gtaatattgc
    61381 tgggaatatt gtacaaaagt aaccactaaa ccaagcgctg ccgctgctgg catagatttg
    61441 tcactgagga caattgttga accgacaaaa atcacgatag ccgtgttaat aaggctcatt
    61501 ccattcatga ctggaaataa ttgtcctgag aacagacggc gtttgaaggt ggcttgtcga
    61561 accctttcat tatgctttaa aaaggctgtc atcgtatctt cttggacacc ttgtacaata
    61621 atagcctttt gtcctgaaat ggtttcatcc ataaaagcat ttaaagcact gacttcttgc
    61681 tgttggatat tggtgtattt tcttgccaaa cggatgttaa tcactaaaaa aatgagagca
    61741 actggggttg atgcgatggt taacaaagct aaacggctat cttgcctaaa catcatccag
    61801 accaggccga tgtaaagggc aatattagtc accacttgaa ccaaggattg gttcagcgag
    61861 ttttgaatat tatccaaatc actcgtgaaa cgagaaagaa tctccccatc tttatggcgg
    61921 tcaaaaaagg cgacggttaa acgttctaat ttaccaaaca agcccttgcg catgcggttg
    61981 gtcgaatgtg agacaacacg tgtaagtaag aaactatata ttagattagc taaaacagta
    62041 aagaaataag tcatcaaaag cttaaacatc acggcattaa aagctgataa atcagggcta
    62101 aaatgtgtct gaccactcat cttagcaacg taataagcct gaccgatttt tcccaactca
    62161 gtcaaggact cccctaagaa gacaggagct tttacttgta aataagttgc taagataacg
    62221 gcaacagcaa tgacagtaaa cgagaaacga tagcgtttaa aataaaacca gaaaaaacgt
    62281 gctgttttca tcactactcc tcccttcctt tttgtgtctc ataaatttca cgataaatcg
    62341 cattattagc caccaactct gcgtgtgttc cttctccaat taactgtcct tggtcaagga
    62401 ctaagatctt atctgcctta actaccgatg aaattttttg agcaacaata actgtagttg
    62461 taccttctaa tttatgactt aaggcttctt gaacgcgttt ttcagatttt gcatcaagag
    62521 ctgaagtgga atcgtctaat ataaggattt tgggatgatt aatgacacca cgtgcaatag
    62581 acagacgttg cttttgtccg ccagacaagt tactacctcg ctcttcaact tggctctcat
    62641 aacggctatc catgcgatca ataaattctt ttgcttgcgc gatttgagcg gctttttgca
    62701 tagcatcaat atcagctttt gctgagcctt ggcgaaggtt atcagctatc gttcctgaaa
    62761 agagaatagc cttttgcaac acgatggaaa ccgattggcg cagggttgtt tgacttaggg
    62821 ttttaatcgg ctttcctcct aacaaaattt ggccatcttg aggatcaaat aagcgaggga
    62881 tgagctgtac aagcgttgat ttcccagatc ctgttgcacc aacgatgccg accatttgcc
    62941 caggttcaat agcaaaagaa atgtgcttca aggttggttc atcatcatta ggatatgtaa
    63001 aactaacatc gtcaaataca atgcttcctg agatggtttc ttccttttca ttttcaaatg
    63061 tcatggcagg ttctgtagac aatatttgcc taattctagc catagaaaca aaagcacgac
    63121 taacttgcat ccccatggaa ccaaccacaa taattgaaaa cataatttgc atcatataag
    63181 tcatgaaaga ggcaatattc ccaatcactg ttggatctgt ttcgaccatg gtcgaaacaa
    63241 catttataga aacataaact gccaaataag acaccaacat taaagccggc tgcattagtg
    63301 aaaaaccata accaatagat aaatttaacg ccaaaagatc attggacgtt tctttaaatt
    63361 tagtgtattg ttgttgttct tgtacaaatg atttaaccac gcgaacgcca cggagatttt
    63421 ccttagcgat gcgattaatc ttatccatta accgttgaaa tttaccaaaa cgaggaccca
    63481 tttgacgcat caccaaaccc atgatgaggg caattaagat aaccattaca acaatgaccc
    63541 accataattg agggaatgtc tgaactgcca tgataaacgc gccaataaaa aggatcggca
    63601 aacgaaagag aatttgaaac atcatcatga ctaaactttg gatttgattg atatcattag
    63661 ttagcctaac cacaagatta ccagcattaa aagcttcaat attggcatat gaaaagtctt
    63721 ggatttttcg aaaggtcttc tccctcatat cagcagatac accttgagct attttagcag
    63781 ctaaaaccgt attaatcgct ccagacatta accctaaaag ggcaataata agtaatggtt
    63841 tcccaacctc ataaattttc tcttgattat tttgaataac agcgcttagc acagatttaa
    63901 gataatgtgg ttgcaagaga ctacttgcaa caaccccaat aaccataaaa aatgagccta
    63961 aagcatacca tttataacgt aagattgcgt ctttaagcat cgttgtctcc tttataagtt
    64021 agcatatttt gcttgagctg ttcaattact tttttcgctg tcagcaactc ttcttttgta
    64081 atttctttta aaaaatagtg ctcgatatcc ttacgacact cccgcaacaa aggcaattta
    64141 tctctaccaa cctgcgctaa cactacttgc ttataacgct tatccacttg ggaaggcatc
    64201 acattgataa acccattttt gaccatacgt ttcactaaat gactagcaac tgactttgag
    64261 atacgaagtt gtttttcaat atctttgaca aatatttctt gattttggtg tttagctaaa
    64321 aaaacaagaa cataaccttg aggacctgct agatgctcta catcatattt ttttgcaatc
    64381 tcatcactaa tttgttcgat ttgatgtatc aattcacgta aatcacctat cacttgtgac
    64441 atctcttccc tccttctttt ccttaatagt ttctatgata agtattttag ttctctagat
    64501 aactattgtc aattaaaata tctttatttt taaaaataag tttccgaact taaataacta
    64561 aaaagaacaa ggcaaagcca tgacaacagc tcacctgatg aagcttatta aacaacatta
    64621 ttaatgtagc tagctctctt gagaacgcct tattagccaa gaccatatac cttttctaat
    64681 agagctaatc aaggtgttat gttataatag agtgactagc tcttgaagga gaatttagaa
    64741 tgacaaaaca aaaagtagct attttaggac ctggttcttg gggaactgct ctttctcagg
    64801 ttcttaatga caatggccat gacgtccgtt tatggggaaa tattcctgat caaattgaag
    64861 agataaatac caagcatacc aatagacact acttcaaaga cattgtgtta gacaaaaaca
    64921 ttacggcaac tcttgattta ggtcaagccc tatcagatgt tgatgcggtg ctttttgttg
    64981 tgccaactaa agtaacacga ttagttgcta gacaagttgc cgccatttta gatcataaag
    65041 tagtggtcat gcatgcctca aaaggtctag aaccagagac ccacgaacgt ttatcaacta
    65101 tcctagaaga agaaattcca gctcattttc gtagtgaagt ggtcgttgta tcaggtccta
    65161 gtcatgctga agaaactatc gttcgcgata ttactctcat cacggcagcc tcaaaagata
    65221 ttgaagctgc aaagtatgtt cagtccctct ttagtaacca ctacttccga ctttatacca
    65281 ataccgacgt catcggagtt gaaacagctg gtgccctcaa aaacattatt gctgttggag
    65341 caggagctct ccatggactt gggtatggag ataatgccaa agcagcggta attactcgtg
    65401 ggttagctga aatcacccgt ctaggcgtca agcttggtgc tgacccgtta acctacagtg
    65461 ggttatctgg tgttggtgat ctaattgtaa caggtacttc tgtccattca cgtaactggc
    65521 gggctggagc tgcccttgga cgtggtgaaa aattagaaga tattgaacgc aacatgggta
    65581 tggttatcga aggcatcgca acaactaagg tagcctatga aattgcccaa gacctcggag
    65641 tttacatgcc aattacaaca gctatttata agtccatcta cgagggcgct gatatcaaag
    65701 aaagcatcct cggcatgatg tcaaatgaat ttcgttctga aaatgaatgg cattaagcca
    65761 tacgtcacta aaataagagg aggtgctgat gaccaaagtc agaaaagcta ttattcccgc
    65821 agcaggttta ggcacacgtt ttttacctgc aaccaaggcc cttgccaagg agatgctacc
    65881 tattgttgat aaaccaacta ttcaatttat cgttgaagaa gctctaaaat caggtatcga
    65941 agaaattctt atcgttactg gaaaatccaa acgctccata gaagatcatt ttgattctaa
    66001 ttttgaatta gaatataatt tacaggctaa aggaaaaatc gaacttctaa agttagtaga
    66061 cgagaccact tctattaacc ttcactttat tcgacagagt catccaagag gattaggaga
    66121 cgcagttctt caagcaaaga cctttgttgg caatgaacct tttgttgtca tgctaggtga
    66181 tgatctgatg gatattacaa atccaaatgt aaaaccatta accaaacaat tgatcgatga
    66241 ctatgaagaa actcatgctg caaccattgc cgtcatgagg gttcctcacg aggatgtctc
    66301 taactacggt atcattgctc ctcaagcaaa agcagtaaaa ggactctata gtgtggatac
    66361 ttttgttgaa aaaccacaac ctcaagatgc acctagtgat ttagcaatta ttggacgtta
    66421 cttgctcaca ccagaaattt ttagtatttt agaaaaacaa gaacctggtg caggcaatga
    66481 agttcaactg actgatgcta ttgataccct caataagaca cagcgtgtct ttgctcgtga
    66541 gtttaaaggg aaacgctatg atgttggcga taaatttggg tttatgaaaa cttctttgga
    66601 ttatgccctg aaacaccctc aagtcaaaga tgacttgaaa gcctacatca tccaactggg
    66661 caaagcacta gagaagacaa aaccataaaa ataaggaggg aaaatccctc cttattttta
    66721 tggtttttaa gtcatttcat cctactagcc atctgagaag taacagtgct aaccactcac
    66781 ttatttttat aaaaacccaa gcactaacac accaaccaaa ataataccat agctcactaa
    66841 agccaacatt cgcttggttt tcttcactgt tatcactctc atcttagttg gaaaaactat
    66901 actcagtaac gcaccaccca cgacaccgcc aatatggcct gccatactca cgtttggcat
    66961 aaaaagattc atcagtaaat tgactacaat taacgtctgg tatgacttgc ccaaatcttt
    67021 caacgcttgg ttcttaccca aaaaactcaa tactacaata gcagcaaaaa gtccaaataa
    67081 cgacgtcgat gctcctgcag ctactgtttc aggagtcaac caaaaagtaa aggcattgcc
    67141 cataacacct gataaaacat aaagtaataa aaaacggcgt gagccccaga ggtcttcgac
    67201 gatttgacca acaaaatata gtgttaatcc attgacaaaa aaatgaccaa agccgatatg
    67261 aataaatatc ggagtcacca atcgccacaa ctggtctggc attgctttta ctagtaatcc
    67321 aaacatacct ccaacttgat aaatagcttg agcaccagtt gctaaatgtc catataccac
    67381 ttgcattgct ataaaaatta agcctgttaa ccctaaaagg aaaatagtaa taggatatcg
    67441 ttttaataac tgtgtcatct aagataaacc tcctaaacag caatatcata aatcgtttga
    67501 tttggcaatc gtatttgccc gctgataagc ttgattgcta acaacatcca ctaataaagc
    67561 ttgatcattt tgacgtttta agtctacatc catagttcgt aaagactaga agagttcttt
    67621 gagaatctct tttttcatca tcttcttatc ataccataaa ttaggaaaaa ggttcaaggc
    67681 tgacaagaaa ctagccacgc cgtacgcatg aaaactttct cttcatcctt ttgtgcccgg
    67741 acatcaattt tgaaaagatt cctttttaaa tcaatcatct gcttagcctc tttctccaaa
    67801 taattg
//
LOCUS       DAUGUF010000005        65440 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUGUF010000005 DAUGUF010000000
VERSION     DAUGUF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65440
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.005"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            26..445
                     /locus_tag="VIB71_000294"
     CDS             26..445
                     /locus_tag="VIB71_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8822055.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKITRAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            442..798
                     /locus_tag="VIB71_000295"
     CDS             442..798
                     /locus_tag="VIB71_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ8822056.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(909..2189)
                     /locus_tag="VIB71_000296"
     CDS             complement(909..2189)
                     /locus_tag="VIB71_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8822057.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSH
                     TPATPSSSSDALAADESSSSGSGSLVPPAINPQT"
     gene            complement(2198..2722)
                     /locus_tag="VIB71_000297"
     CDS             complement(2198..2722)
                     /locus_tag="VIB71_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8822058.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNIKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDIYHMRKSVSQ"
     gene            complement(2697..3158)
                     /gene="tsaE"
                     /locus_tag="VIB71_000298"
     CDS             complement(2697..3158)
                     /gene="tsaE"
                     /locus_tag="VIB71_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEQ8822059.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            complement(3312..4772)
                     /locus_tag="VIB71_000299"
     CDS             complement(3312..4772)
                     /locus_tag="VIB71_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEQ8822060.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            5036..5848
                     /locus_tag="VIB71_000300"
     CDS             5036..5848
                     /locus_tag="VIB71_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8822061.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTSYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            6200..7192
                     /gene="manX"
                     /locus_tag="VIB71_000301"
     CDS             6200..7192
                     /gene="manX"
                     /locus_tag="VIB71_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEQ8822062.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPERKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            7281..8090
                     /locus_tag="VIB71_000302"
     CDS             7281..8090
                     /locus_tag="VIB71_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEQ8822063.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            8107..9018
                     /locus_tag="VIB71_000303"
     CDS             8107..9018
                     /locus_tag="VIB71_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8822064.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            9132..9491
                     /locus_tag="VIB71_000304"
     CDS             9132..9491
                     /locus_tag="VIB71_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEQ8822065.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            9882..11159
                     /gene="serS"
                     /locus_tag="VIB71_000305"
     CDS             9882..11159
                     /gene="serS"
                     /locus_tag="VIB71_000305"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEQ8822066.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFNFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(11381..12151)
                     /locus_tag="VIB71_000306"
     CDS             complement(11381..12151)
                     /locus_tag="VIB71_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEQ8822067.1"
                     /translation="MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYKMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(12148..13014)
                     /locus_tag="VIB71_000307"
     CDS             complement(12148..13014)
                     /locus_tag="VIB71_000307"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEQ8822068.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKEQKIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            complement(13023..14387)
                     /locus_tag="VIB71_000308"
     CDS             complement(13023..14387)
                     /locus_tag="VIB71_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEQ8822069.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRHNQKVLEESPSIAIGNTLRHEMGQAAVRAAKAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            complement(14419..14841)
                     /gene="fabZ"
                     /locus_tag="VIB71_000309"
     CDS             complement(14419..14841)
                     /gene="fabZ"
                     /locus_tag="VIB71_000309"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEQ8822070.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            complement(14838..15338)
                     /locus_tag="VIB71_000310"
     CDS             complement(14838..15338)
                     /locus_tag="VIB71_000310"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEQ8822071.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            complement(15340..16572)
                     /gene="fabF"
                     /locus_tag="VIB71_000311"
     CDS             complement(15340..16572)
                     /gene="fabF"
                     /locus_tag="VIB71_000311"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEQ8822072.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWDNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            complement(16587..17321)
                     /gene="fabG"
                     /locus_tag="VIB71_000312"
     CDS             complement(16587..17321)
                     /gene="fabG"
                     /locus_tag="VIB71_000312"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEQ8822073.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPIKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            complement(17311..18249)
                     /gene="fabD"
                     /locus_tag="VIB71_000313"
     CDS             complement(17311..18249)
                     /gene="fabD"
                     /locus_tag="VIB71_000313"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEQ8822074.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHEVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            complement(18274..19245)
                     /gene="fabK"
                     /locus_tag="VIB71_000314"
     CDS             complement(18274..19245)
                     /gene="fabK"
                     /locus_tag="VIB71_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEQ8822075.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            complement(19447..19671)
                     /locus_tag="VIB71_000315"
     CDS             complement(19447..19671)
                     /locus_tag="VIB71_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8822076.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            complement(19732..20706)
                     /locus_tag="VIB71_000316"
     CDS             complement(19732..20706)
                     /locus_tag="VIB71_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEQ8822077.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            complement(20707..21141)
                     /locus_tag="VIB71_000317"
     CDS             complement(20707..21141)
                     /locus_tag="VIB71_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8822078.1"
                     /translation="MEYDKINHYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            complement(21215..22006)
                     /locus_tag="VIB71_000318"
     CDS             complement(21215..22006)
                     /locus_tag="VIB71_000318"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEQ8822079.1"
                     /translation="MQFKHIIFDVVDDLAILTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGVDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            complement(22228..23364)
                     /gene="dnaJ"
                     /locus_tag="VIB71_000319"
     CDS             complement(22228..23364)
                     /gene="dnaJ"
                     /locus_tag="VIB71_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEQ8822080.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTSHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(23645..25471)
                     /gene="dnaK"
                     /locus_tag="VIB71_000320"
     CDS             complement(23645..25471)
                     /gene="dnaK"
                     /locus_tag="VIB71_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEQ8822081.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDARLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(25652..26224)
                     /gene="grpE"
                     /locus_tag="VIB71_000321"
     CDS             complement(25652..26224)
                     /gene="grpE"
                     /locus_tag="VIB71_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEQ8822082.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELVNERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(26227..27261)
                     /gene="hrcA"
                     /locus_tag="VIB71_000322"
     CDS             complement(26227..27261)
                     /gene="hrcA"
                     /locus_tag="VIB71_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEQ8822083.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(27397..27966)
                     /locus_tag="VIB71_000323"
     CDS             complement(27397..27966)
                     /locus_tag="VIB71_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8822084.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(27963..28706)
                     /locus_tag="VIB71_000324"
     CDS             complement(27963..28706)
                     /locus_tag="VIB71_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEQ8822085.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDSQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGT
                     SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            complement(28696..29403)
                     /locus_tag="VIB71_000325"
     CDS             complement(28696..29403)
                     /locus_tag="VIB71_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8822086.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEIDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            complement(29795..30034)
                     /locus_tag="VIB71_000326"
     CDS             complement(29795..30034)
                     /locus_tag="VIB71_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8822087.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(30253..30468)
                     /locus_tag="VIB71_000327"
     CDS             complement(30253..30468)
                     /locus_tag="VIB71_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822088.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTVYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNHHVCLHYY"
     gene            complement(30465..31904)
                     /gene="gatB"
                     /locus_tag="VIB71_000328"
     CDS             complement(30465..31904)
                     /gene="gatB"
                     /locus_tag="VIB71_000328"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEQ8822089.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIKIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKVLSDYFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            complement(31904..33370)
                     /gene="gatA"
                     /locus_tag="VIB71_000329"
     CDS             complement(31904..33370)
                     /gene="gatA"
                     /locus_tag="VIB71_000329"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEQ8822090.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIAFPKEYLGEGIDPKIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPAVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(33370..33672)
                     /gene="gatC"
                     /locus_tag="VIB71_000330"
     CDS             complement(33370..33672)
                     /gene="gatC"
                     /locus_tag="VIB71_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEQ8822091.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(33904..34223)
                     /locus_tag="VIB71_000331"
                     /pseudo
     CDS             complement(33904..34223)
                     /locus_tag="VIB71_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991537.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
     gene            complement(34667..35221)
                     /locus_tag="VIB71_000332"
     CDS             complement(34667..35221)
                     /locus_tag="VIB71_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEQ8822092.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(35368..36150)
                     /gene="codY"
                     /locus_tag="VIB71_000333"
     CDS             complement(35368..36150)
                     /gene="codY"
                     /locus_tag="VIB71_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEQ8822093.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILRELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(36368..37582)
                     /locus_tag="VIB71_000334"
     CDS             complement(36368..37582)
                     /locus_tag="VIB71_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8822094.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDSK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            37813..38265
                     /locus_tag="VIB71_000335"
     CDS             37813..38265
                     /locus_tag="VIB71_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEQ8822095.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNTKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(38388..39776)
                     /locus_tag="VIB71_000336"
     CDS             complement(38388..39776)
                     /locus_tag="VIB71_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8822096.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDVEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAVNKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            39848..40813
                     /locus_tag="VIB71_000337"
     CDS             39848..40813
                     /locus_tag="VIB71_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEQ8822097.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(41162..41866)
                     /locus_tag="VIB71_000338"
     CDS             complement(41162..41866)
                     /locus_tag="VIB71_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822098.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(41879..42781)
                     /locus_tag="VIB71_000339"
     CDS             complement(41879..42781)
                     /locus_tag="VIB71_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8822099.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIYEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            complement(43074..45089)
                     /gene="recG"
                     /locus_tag="VIB71_000340"
     CDS             complement(43074..45089)
                     /gene="recG"
                     /locus_tag="VIB71_000340"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEQ8822100.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENKSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDARMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     YKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAQNIRKKEVYD"
     gene            complement(45464..46918)
                     /locus_tag="VIB71_000341"
     CDS             complement(45464..46918)
                     /locus_tag="VIB71_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822101.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVPTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQDLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(46855..47535)
                     /locus_tag="VIB71_000342"
     CDS             complement(46855..47535)
                     /locus_tag="VIB71_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8822102.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(47532..48125)
                     /locus_tag="VIB71_000343"
     CDS             complement(47532..48125)
                     /locus_tag="VIB71_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEQ8822103.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            complement(48122..49792)
                     /locus_tag="VIB71_000344"
     CDS             complement(48122..49792)
                     /locus_tag="VIB71_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822104.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            complement(49785..51548)
                     /locus_tag="VIB71_000345"
     CDS             complement(49785..51548)
                     /locus_tag="VIB71_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEQ8822105.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQEIINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGKLLSPGQKQQVICVRALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLSTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(51545..52381)
                     /locus_tag="VIB71_000346"
     CDS             complement(51545..52381)
                     /locus_tag="VIB71_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822106.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            complement(52378..53400)
                     /locus_tag="VIB71_000347"
     CDS             complement(52378..53400)
                     /locus_tag="VIB71_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8822107.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVTYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AITGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(53402..54286)
                     /gene="isdE"
                     /locus_tag="VIB71_000348"
     CDS             complement(53402..54286)
                     /gene="isdE"
                     /locus_tag="VIB71_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEQ8822108.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSVNPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHP"
     gene            complement(54283..55146)
                     /locus_tag="VIB71_000349"
     CDS             complement(54283..55146)
                     /locus_tag="VIB71_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEQ8822109.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDSQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKREKK"
     gene            complement(55343..59170)
                     /gene="shr"
                     /locus_tag="VIB71_000350"
     CDS             complement(55343..59170)
                     /gene="shr"
                     /locus_tag="VIB71_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ8822110.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEALVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQGSLKKDVLSDKTVPQN
                     QGTQKVVKSGKNTTNLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVIITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(59660..61189)
                     /locus_tag="VIB71_000351"
     CDS             complement(59660..61189)
                     /locus_tag="VIB71_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8822111.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRTPI
                     QSLSPYVSDLDLNEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKS
                     TGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAF
                     DLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFT
                     DTTGSGKRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLD
                     YQASSYAWGQCTWYVYNRAKELGYRFDPFMGNGGDWKYKVGYALSKTPKVGYAISFAP
                     GQAGADGTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSK
                     N"
     gene            complement(61276..62376)
                     /locus_tag="VIB71_000352"
     CDS             complement(61276..62376)
                     /locus_tag="VIB71_000352"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEQ8822112.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGVTYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLSKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(62373..62729)
                     /locus_tag="VIB71_000353"
     CDS             complement(62373..62729)
                     /locus_tag="VIB71_000353"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEQ8822113.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFVKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(62845..65364)
                     /gene="secA"
                     /locus_tag="VIB71_000354"
     CDS             complement(62845..65364)
                     /gene="secA"
                     /locus_tag="VIB71_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEQ8822114.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
BASE COUNT        20025 a        13903 c        11298 g        20214 t
ORIGIN      
        1 attcaagtag agaaggtgat ataaaatgga aaattgtatt ttttgcagca tcattcaagg
       61 ggatatcccc tcttcgaaag tctacgaaga tgagcaggtc ctcgcctttt tagatatctc
      121 acaaactaca aaagggcata ctctagtcat tcctaagcaa catgttcgta acttactaga
      181 gatgactgct gagacagcta gtcatctctt tgctcgtatt cctaaaatta ctcgtgctat
      241 ccagtcagct actggcgcta ctgccatgaa tatcattaac aataacgaag ccttagcggg
      301 acaaactgtt ttccatgctc atgttcatct cgttcctcgt tataatgaag aagacggtat
      361 ctcaattcaa tacaccactc atgagcctga ctttcctgtc ttggaaaagc tcgcccgaca
      421 aatcaatcag gaggttagtt catgaaagtt aaaaccgtga tagccgtcgg attattatct
      481 tttaccgctt acaaagcata tcaaaaacgt tgtaccataa aagagctgtt atccatcagt
      541 cgacaagcaa aggatgctgc acaacttgat ttagataaca ttaaagcaaa ccttgacctc
      601 attcacagtc aaggaaaagt aattcaaaat attagtcagg acttggccca taaatggcgc
      661 tactttaacc aagagacaca agcacacctc actgaaatcc aaaatcgtat ggccaaatat
      721 caagaagata gtgagctaat ttctagtgaa tcacctactt gccaaaccgt cattttaact
      781 aacaaccatt ccagatagta ttatctccct catatacttt atttgaaatc acagacagct
      841 atcatctttg atacctgtct tttttatatt caaaatcgga taccttaaac ataaaaaccc
      901 tcagaacgtt aggtctgagg gttgatagca ggaggaacta atgatccaga ccctgatgag
      961 ctagattcat cagctgctaa agcatctgat gaagaagacg gcgtagctgg cgtatggctt
     1021 gaagcagtag agtcctggtc tgtactagca ctctgataag atgagccagt atctactccg
     1081 cttgaataat tagcgtaaga gctatgacta tcagaataag atggagcctg gcctgaagag
     1141 tcatagttgt tgtttactgt ctgagactta gttgacccat acaaattttc ataaacagta
     1201 gcatttgttt ttaattgact aaccttatga agtcctaatt ctgttcggat acgattttgg
     1261 atttctaaca aatgattaga ggtgacaatt tggtatgatc caccatctga taaagtggca
     1321 tcttctcctt ttagttgata agttttaata gttctaagtg cgtcacgata tcctaataga
     1381 ctagggatag tgcgagaaga gatttcgata ttcgtttgca tattactact tacagcagat
     1441 aaaatcttcc gataagagct aatgctatca agagcaagga tttttttcaa taccttttga
     1501 atgacttcac gttgacgctt ttgtcgacca taatctccct caggatcatc ataacgcata
     1561 cgagcataaa ccaaagcttg ttcaccgtta attttgtgtg ttccaggcgc aacagtagct
     1621 tgatattcag gttcgttttc agcaatcgag ataggaaaat caaactcatt tgtaactgta
     1681 atccctccaa ctgcattcac aagatcaata aggccttgca tattaatttg aacatagtta
     1741 tcaatggtga tattcaaaag atcttgcacg gtcataatag ccatctgagc gccacctgct
     1801 gcataagcag cattaagctt agcttcaaca ccattcattt cattattttt gggtccagat
     1861 aacgtggtta aggtatctcg ttctaaacta gtcatagttg ttttcttggt ctttggatta
     1921 accgtaacca aaatcatcga atcactgttt ccttcccact tggaggcacg ctctgaagag
     1981 cctgtatcaa cacccatcaa caagatagaa aaagctcttg tttgtttaat ggcatcactt
     2041 ttctttgaag atgtcgaaaa atctttaaag gtctttgata attctcctgt tgagaaggta
     2101 taagcactag ttagatagac acctaatgcc aagacagttg ttaacacaat agctgtgaac
     2161 attaaaacta ttttttttcc aattttcatc gattcactta ctgacttaca gatttacgca
     2221 tatgataaat atctaagtca tctccatttt ttgatttgat gtcgtttttt cgcatacttt
     2281 caatacgaaa accatacttt ttatacaggt aaatagcctt aatatttctt acttgaacgt
     2341 ccaacttaag gctttcgata taagggtttt cttcagccca atcaagagca atctctaaca
     2401 ataattgacc gataccataa ccacggtaag tcttagcaac taacataaat acatctgctt
     2461 caacttggcc ttgggataat acttccccag aaagatttaa aagccctact actttttcat
     2521 ctaatctagc tagcaggcaa aaatcaataa aagaggtttg acttcttgat aaaaagtctg
     2581 acaattcttg aggagtagcc tctaatatag tctctacgcc tgttataaaa tctgtttctt
     2641 tggcagctgc cgtcactaag gaaagtacag cttttgcatc ttgaggtact ccttcttcaa
     2701 taacgagact ttgctgaatc atgtgacatt atctccagaa gctgacgaga gcgctcacca
     2761 tgcgctaaca agtctagttg acgacctttg tctcgtttag taatggtaat ttgcaaatag
     2821 tcttgtaata atccctctcc taataattct ccccactcaa taacggtaac accattacca
     2881 aaaagaaaat catctaaatc aatagagtct ggatcatcac caacacggta aatatctaag
     2941 tgataaagag gtagacgtcc ttcatattct ctaacaatag tataagttgg gcttttgatc
     3001 atttgactaa tccccatccc tttagcaata ccttttgcca atgttgtttt accggcacct
     3061 aagtcgccag acaatacaat cacatctcca atagacaaat aagtacctag ggtttctccg
     3121 taagctttaa gagtatattc attttcacta taaaacatag caacattata tcagaaaaaa
     3181 aacatacttc caagcactac ctagaagatg actccaataa ggtattcgta aagtaaaaac
     3241 gcttctttat attaaaggtt aaaatcaatt aaagaagcgg cagttagtag caaaataagt
     3301 aaattatttg gttataagat agttaatatg atgaaattta caatgaacaa gaaggttgct
     3361 ccccaaataa tagggtgaat atcttttgtt tttccctcaa caacttttac tagacaatag
     3421 aaaataaagg cagcggcaat accataggaa atagagtaac acagcgccat aaagaaagcg
     3481 gcaaaaaaag ctggaagagc atctgcaaat ttactccaat taacatcaag aaaagaagac
     3541 accatcatga cacccacaac aattaaagct ggagccgtag cagcagctgg gacaatacct
     3601 acaagcggta atagcaatat tgataataag aagcatactg cggtggagac tgctgttagt
     3661 ccagtacgtc caccttcagc aattcctgct gctgattcaa cataggtagt cgtatttgaa
     3721 gttccaacca aagccccaat agaagtaccg atagcatctg caaaaagcgc acgatccatt
     3781 tttgaactaa agcctatact attttccaaa gcattctcat cgtcttgaga gaaaatacct
     3841 gttcgacgac cagttccgat aaaggtacca attgtgtcaa aagtatctga tagactaaaa
     3901 gcaaaaatag tcatgaaaac tagcggtaaa cgacttgaat cgctaaaaag agaactcaaa
     3961 ccatcgaaag ctgcaaggaa agttgtacct aattcagtcc aagcttcacc aatatggctg
     4021 atcccaaaat tgaggttgga cacatccact attcctaaag gaatacctac aagagttgtt
     4081 gcgacaatac caattaaaat agcacctcta aaatttcgaa tcacaagagc tgtcgttaaa
     4141 agtaaaccaa aaatagcaag taatacacta gaatccgtaa aactagaaat cgtaggtaca
     4201 actccaccat tggcgtctac aaataataga ccatctgcaa atgttttagc cgatgcttta
     4261 gccggttcaa caccatttac cattactata ttttcagcag agatagaaaa agtaatgata
     4321 tttgcgtttt taaatcctaa ataagctaca aagacaccaa ttcccccacc aatagcatgc
     4381 tgtaaactaa ctggaatcgc cttgatgata cttttacgaa acttggttac ggtaataaaa
     4441 atattgaata atccacaaat gaaaaccatt gccaaggctt cttgccatga aaagcctaaa
     4501 gcaaaaacaa ctgtataagt gaaaaaagcg ttaagtccca ttcctggtgc cagcgcataa
     4561 ggcacattgg caaataatcc cataattaag gttgatatgg ctgctgcgat aatcgtagcc
     4621 aaaaagacag cattagaggg catccccgct gcacctaaaa tacttgggtt aacaaacaaa
     4681 atataggaca tggcaaaaaa ggtcgttaaa ccagccataa tctcagttga gacagttgtc
     4741 ccattttcgc ttaacttaaa aaacttttcc attgaaatgg agtctcctta attaaatagt
     4801 aggtaaaatc aaaaagcgct tatcactaga taagtctttt tgacacctca ttattattgt
     4861 tattgttcgt attaaaatga acaataacac tatgttacca tttttttgtt cacttttcaa
     4921 cgtctatacc ttcatttatt cattaaaaaa acagttatcc tatctttttt actaatgaat
     4981 acgcttaact tatcttttct ctttatcttg gagcaaaatt tgctataatt taattatgac
     5041 taaaaaattg attgccattg atttggatgg aaccttatta catcatgaca acaccatctc
     5101 tacctatact caaaaaacca tcaaagctgt ccaagacaag ggtcaccacg tcattatttc
     5161 aacaggccgt ccttaccgca tggcactgga ctactatctg cagctcaatt taaagacccc
     5221 aatcattact tttaatgggg ccttgaccca catgcctgaa caaaaatggg cctatgaaca
     5281 taatgtcact ttggacaaag gctacctact aaggttacta aaatatcagg atgatttcca
     5341 gatggatttt attgccagtg agtatcgaaa aaatgtctac atcaccatga ccaatccaga
     5401 aagtatcgac ccgcaactct ttggtgttga tgaaattact caggacatgg cattagagat
     5461 taccaaaatc actcgaaatc caaacgcctt attgatgcaa acgcatcacg aagacaagta
     5521 tgccttagct aaaaacatgc gtgctttctt caaagatgaa attgaaattg attcttgggg
     5581 aggccctctc aacattcttg aaatttcgtc taagaatgtc aataaagctt acgctctgaa
     5641 ctatctcctt ggaatttaca atatggataa aaaggattta atcgcctttg gtgatgaaca
     5701 caatgacact gagatgctag cttttgctgg aactagttat gctatgaaaa atgctagccc
     5761 tgtgctactg ccttatgctg atcagcagct taatttttcc aacgaagaag acggtgttgc
     5821 caaaaaattg gaagaacttt tcttgtagta gcaaacgaaa ccactatttt tcagaaaatg
     5881 gtggttcttc ttctgtcaac agctatcaaa aaatgaaaat cattttaata atttcaacat
     5941 ttttcagcat atttttgttt taaacagctt gaaaacacct ttaatatcaa taatctgcct
     6001 atttaatcct aaattctgaa aattttttca tgttttgtac tatttttccg aaagggcttg
     6061 attttttagt gaaaacgttt taaaatagaa acgttcttga atttcgttta agtgaaaaag
     6121 aattgccaaa atttagtttt ggaaggagat tattcttctt catttcaacg aaaaatattt
     6181 taaaggagga agaacaagaa tgggtatcgg tattattatt gccagccatg gtaaatttgc
     6241 tgaaggtatt catcaatctg gttctatgat ttttggtgaa caagagaaag ttcaagttgt
     6301 tactttcatg ccaaacgaag gaccagatga tttgtatgga cacttcaaca atgctatcca
     6361 acaatttgat gctgatgatg aaatccttgt gctagctgac ctttggagtg gttctccatt
     6421 taaccaagct agtcgtgtgg caggtgaaaa tcctgagcgc aaaatggcga tcatcactgg
     6481 tctcaacttg cctatgctta ttcaagctta cactgaacgt cttatggatg ctggtgcagg
     6541 tgttgaacaa gttgctgcaa acatcattaa ggaatctaag gacggtatca aagcccttcc
     6601 tgaagacctt aacccagttg aagaaactgc tgcaactgaa aaagttgtta acgcacttca
     6661 aggagctatt cctgctggaa ctgtcatcgg agatggtaaa ttaaagatca atcttgctcg
     6721 tgttgacact cgtcttttac acggtcaagt tgcaacagca tggactccag cttctaaggc
     6781 tgaccgtatc attgttgctt ctgatgaggt tgctcaagat gaccttcgca aacaattgat
     6841 caaacaggct gcacctggtg gtgtcaaagc taacgttgtt ccaattagca aattgattga
     6901 agcttctaaa gatcctcgtt ttggtaacac acacgcactt attcttttcc aaacccctca
     6961 agatgccctt cgcgcggttg aaggtggtgt tgaaatcaac gaattgaacg ttggttcaat
     7021 ggctcactca actggtaaaa caatggttaa caacgtttta tcaatggaca aagaagacgt
     7081 tgctactttt gaaaaattac gcgacctagg tgttacattc gacgtccgta aagttcctaa
     7141 cgattctaag aaaaacttat ttgagcttat ccaaaaagct aacattaaat aagtttcaaa
     7201 cgctataagg ttttaaaacg atgactagct aacttattag caaaaagtcc tcgtttacta
     7261 tactttgaaa ggattacaac atgtcagata tttcgattat ttctgcaatt ttggtcgtta
     7321 tcattgcctt cttcgctggt cttgaaggta tcctcgacca atttcaaatg caccaaccac
     7381 ttgttgcctg tactttgatt ggacttgtaa ctggacacct tgaagctggt gtcatccttg
     7441 gtggtacact tcaaatgctt gctcttggtt gggcaaacat cggtgctgcc gttgcccctg
     7501 atgctgccct tgcctctgtt gcagctgcta tcatcatggt caaaagtggc gactttactc
     7561 aaaaaggaat tacctttgct tactcaacag ctatcccact tgctgttgct ggtcttttcc
     7621 ttacaatgat cgttcgtact ttgtcaactg cccttgtaca cgctggtgac aaagctgccg
     7681 ctgaaggtaa tttcgcaggt attgaacgct tccactttat tgcccttctt cttcaaggat
     7741 tgcgtatcgc tgtcccagca gctcttcttg ttgctgttcc tacttcagcc gtacaatctg
     7801 ttttgaatgc tatgccaaac tggttgaacg aaggtatgca aatcggtggt gcgatggttg
     7861 ttgctgtagg ttatgctatg gttatcaaca tgatggctac tcgtgaagta tggccattct
     7921 tcgccctagg ttttgctctt gcagctatta gccaattaac ccttatcgct atgggtgtta
     7981 tcggtgtagc aattgccttc atctacctta atctttctaa aaaaggtggt aacggtggta
     8041 atgcagcagg ttcagctgat ccaatcggcg acatcttaga agactactag aaaggggtaa
     8101 gaacaaatga ctgaacaaat taaattaact aaatcagacc gtcaacgtgt ttggtggcgt
     8161 tcacaattct tacaaggttc ttggaactac gaacgtatgc aaaacatggg ctgggcttat
     8221 gcacttatcc ctgctcttaa aaaattgtat acgtctcctg aagaccgtgc agctgctctt
     8281 gagcgccaca tggaattctt taacactcac ccatacgttg cagctccaat cattggtgta
     8341 acacttgccc ttgaagaaga acgcgcaaat ggtacgccaa ttgatgacaa ggctatccaa
     8401 ggggttaaaa tcggtatgat gggacctctt gctggtatcg gtgacccagt attctggttt
     8461 acggttcgtc ctatccttgg ggcacttggt gcttctttgg cttcaacagg taacatcgtt
     8521 ggtccacttc tgttcttctt tggatggaac cttatccgta tggccttctt atggtatact
     8581 caagaatttg gttacaaagc tggttctgaa attactaaag acatgtcagg cggtatcctc
     8641 caagacatta ctaaaggtgc ttcaatcctt ggaatgttta tccttgcagt gcttgttcaa
     8701 cgttgggtat ctatcaactt tactatcgac cttcctggaa aacaattgtc agatggtgcc
     8761 tatgtggtct tcccagatgg cgctgttaaa ggtgctgagt tgaaaactat ccttgccaac
     8821 gctattggcg gtatgagcct tgataaagtc caagctcaaa cccttcaagg acaattggac
     8881 tctcttatcc caggtttagc tggattactc cttacattcc tttgcatgtg gttattgaag
     8941 aaaaaagttt ctccaatcgc aatcatcatc ggcttgtttg catttggtat ccttgctcac
     9001 cttgcaggta ttatgtaatc aaccaatgga agtctgagat gaactcaggc ttctttttta
     9061 tgctttatgt caggaaaatc ccacttaaaa tatggtataa taactacaac tacgcaatga
     9121 aaggaactaa aatggctcaa tctttaaaca ctagtgtcga atacaagaca aaagctgtct
     9181 cctaccttgg aatgggaggc aaagttggtc atattttact cggtgacaag gcccttgaat
     9241 tttacaacga taaaaatgtg aatgattata ttcaaattcc ttggacagct atcaatcaca
     9301 tcggggctaa tgtttcaaga aaaaaagtta gccgccactt tgaaattttt acggaccaag
     9361 gcaagttttt atttgcttct ggagactctg gaaaaatctt aaaaatcact cgtcaacata
     9421 ttggtaatga gaaagtgatt acattaccaa ccttgatgca aacctttatt aacaaatttt
     9481 ttcgacatta aaaaaataat gcgcagtgcc gatttatcat ttcaagaaaa caaagaatag
     9541 tagctctaaa ttgctattta gtggaaaaga ttccctcatt tgagtttact ttttcttgtt
     9601 ttttgttata atagtcctaa cggataagta ataccttttt tcattcagag agtctgtgga
     9661 tgctgtgaac agatagggaa aatggtatga aattctaccg tgtcatcaat aaaatagaga
     9721 ttaagtgcac agattgtgaa gctggatgga accgcgccaa agcgctccag catcttcata
     9781 agctgtgctt tttctatcgt cagagaatca caagatccaa ctgtcttact tagccttgtt
     9841 tcactgacag ctactaataa ctatcttaaa ggagcttctg tatgctagat cttaaacgta
     9901 tccgtactga ttttgacact gtcgctgcca aattaaaaaa ccgtggtgtt tctgaagaca
     9961 ccctgaccca tcttaaagaa cttgatgaaa aacgtcgtac tctattagtg caatcagaag
    10021 aattaaaagc agagcgtaat attgcttctg ctgccatcgc tcaagccaaa cgtcaaaaag
    10081 aagatgccac tcaacaaatt gctgatatgc aaaaagtctc tgcagatatc aaaactattg
    10141 acaatcaact agtagctatc gaccagcaag ttactgacat catcactgtt ttacctaata
    10201 ctcctcacga ttctgtccct gttggagctg acgaagaaga caatgtcgaa attcgccgtt
    10261 ggggaacgcc tcgtgacttt aacttcgaag ttaaggctca ttgggatcta ggcgaagatc
    10321 ttgatatttt agactgggaa cgtggggcaa aggtaactgg tgctcgtttc ttattctata
    10381 aaaatcttgg tgctcgtttg gagcgtgctc tttataactt catgctggat gaacatatca
    10441 aagaaggtta tcaagaaatc atcacacctt acatggttaa ccacgattcc atgtttggta
    10501 caggacaata tccaaagttc aaagaggaca cctttgaatt agcagatacc aactttgtcc
    10561 tgattccaac tgctgaagtg cctttgacca attattaccg tggggaaatc ctagacggca
    10621 aagaattgcc aatttacttt actgcaatga gcccatcttt tcgttctgaa gcgggttctg
    10681 cgggtcgtga cacacgtggc cttatccgcc tacaccaatt ccacaaagtt gaaatggtta
    10741 aatttgctaa accagaagaa tcttaccaag aactagaaaa aatgactgct aatgctgaaa
    10801 atattcttca aaaacttggt ttgccatatc gcgtcatttc cctttgtact ggcgacatgg
    10861 gcttctcagc tgctaaaacc tatgaccttg aagtctggat tcctgcacaa aacacctacc
    10921 gtgaaatttc atcatgttca aatactgaag atttccaagc acgacgtgct caaatccgtt
    10981 accgtgatga ggctgacggt aaggtcaaac ttctccacac ccttaatggg tcaggacttg
    11041 ctgtcggtcg taccgtagca gccattttag aaaactacca aaatgaagat ggttctgtta
    11101 ccatccctga agtactccgc ccttacatgg gtggcgaaac cgtcatttca cctaaataat
    11161 aaattcaccc cagagatcat taaagtgatt tctggggttt actattttaa agagccacca
    11221 catcacttga aactcactac attgcccctt taacaacact tttcttcaca ctagtttatc
    11281 aaaagtctta ttagtatacc catttcctta tttacaagac tagttaaaaa cccttttgga
    11341 aaggcctccc ttcacgtagg gagactccaa aaggatgttg ttaatattta cgaaagcgtt
    11401 ggtagcgctc atctaataat tggtctaatg gcttagcttg caaactggtt atttgttcga
    11461 tgaggttagc tttgatgata tcaacgattt cacttgaaaa ataaccatgt tctggaataa
    11521 tacggtctac tattcccatt ttgtagagtt cacccgctgt gattttcatc aattcagcgg
    11581 cctcggtcgc ccttgaacca tccttccata aaatagaagc aaagccttct gggctaagaa
    11641 ccgcatacat agtattttca agcatccaga cctgatcggc aaccgctaag gctaatgcac
    11701 caccagagcc tccttcacca ataatgatgg cgataatggg aaccttgaga tcactcattt
    11761 ccatcaaatt tttagcaatg gcctcaccct gtcctcgttc ttccgcaccg acacctggat
    11821 aggctcctgc agtattgata aacgtaacaa cgggtcgtcc aaatttttct gcctgtttca
    11881 taaggcgcaa agctttacga taaccttctg gattgggctg gccaaaattc cttgccaaat
    11941 tatcctgtaa attcttacct ttttgaatac caatgaccgt aacaggttgt cccgccaaat
    12001 aagctaggcc acctacaatg gcaccatcat ctgaaaaatg gcgatcgcca tgcagttcca
    12061 taaagtcatc gaaaataagg ttggcgtaat ccaaagttgt taaacgccct tgatcacgcg
    12121 cttcttttaa aactcttgat acatctgtca ttggccacct ccatgaaatg ctactaagtg
    12181 ggcaatcttg tctcgcaact ctgttcgttt cacaatagca tccacaaaac catggtcttg
    12241 taaaaattct gctttttgaa aatcatccgg caaattctca cgtactgtgg tttcaataac
    12301 acggcgtcca gcaaatccaa ccaaggattg aggttctgct aaaataatat ccccttccat
    12361 ggcaaaacta gctgttaccc caccagtagt tggatctgtc aaaatagtga ggtaaaagag
    12421 gcctgcatta gaatgtcttt tcacagctgc agagaccttg gccatttgca taaggctcat
    12481 aatcccctct tgcatacggg cgcctcctga agccgtaaaa atcaccaccg gcaggttttc
    12541 ttcgatagcc aattcaaaca atcgggtaat tttttcccca acaacagttc ccatactagc
    12601 cataataaag tgagaatcca taatagcaag agcaatcttt tgctccttaa ccatagcctt
    12661 ccctgtcaaa acagcttcat gcagaccagt tgtttccttg gctttttgta atttttcctg
    12721 ataacctgga aaacgtaacg gatccttggt ttcaatactt gtaaataatt cctggaaaga
    12781 gccttcatca actgttaagg tcagccgctc ttgggcagaa atcctaaaat tgtaagaaca
    12841 ggttgggcaa atctttgcca atcccaaatc tttcttataa atcatgtgct tacaagctgg
    12901 gcatttcgca aagagttcat ctggaacttc tgggacatta tggctgacag atcctttgag
    12961 ggaattattg ggagtaatac ggatgtattt atctttttta cgaaataaag ccatattttc
    13021 tcctaatctt tattgtaatg tggcaggaac gtttccatca agaaagaggt atcataatct
    13081 cctgcaatca ctcgcttatc tgaaatcaaa tcgagctgga agtctgtatt ggtgataatg
    13141 ccttcaattt ccaattcaac taaggcacgt tgcattttca tcaaagcgtc aaatcgattg
    13201 cttccatgaa cgatgatttt agcaatcatg ctgtcataat aaggaggaat ggcatagcca
    13261 ttgtaaactg ctgaatcaac tcgtagtcct acaccaccac ttggcatata caagtctgta
    13321 atctttcctg gactcggtgc aaagttaaaa gcagtatttt cagcattgat acgacattca
    13381 atagcatgtc ccgtgatagt gatgtcttct tgattaatcg ccaaaggctg acctgctgca
    13441 attttgattt gctctttgac aatatccact cctgtcacaa attcggtgac aggatgctca
    13501 acttggatac gggtattcat ttccatgaaa tagaatttct cgctgtcttc gtccaacaaa
    13561 aactcaatgg ttcccgcatt ttcataggct acagctttag ctgctctaac cgctgcttgc
    13621 cccatttcgt gtctgagggt attgccaata gcaatggatg gactttcttc caagactttt
    13681 tgattatgac gctgtaacga gcaatcccgt tctcccaagt gaatgatgtt accgtaagcg
    13741 tctcctaaaa tttgcacctc aatatgtcta gctgggtaaa ttactttttc caaatacatg
    13801 gcgccatttc cgaaagctcc caaagcttct tgactggcag cattgaaagc cgcctccaaa
    13861 tctgcttctg tctccacttt acgaatccct ttacctccac cacctgccga tgcttttagc
    13921 atgacaggat aaccaatctt attggcaata gctaaggctt cttgagcgtt ataaacttca
    13981 ccatctgacc ctggaataac gggcactcct gccttaatca tttcagaacg agcattgatt
    14041 ttatcaccca ttttatccat aaccgatgcg gatggaccga taaatttaat attcatctct
    14101 tcacacatgg tcgcaaactt tgagttttca cttaaaaagc caaaccctgg gtgaatcgct
    14161 tgggctcctg tcacaatagc tgctgacaag acggaattca tattaagata ggattccttg
    14221 gaacgggcag gaccaataca gatagcctca tccgccaata tcgtgtgcag agcttcctta
    14281 tccgcttccg aataaactgc aactgtggaa atccctaatt ctcgtgcagc acgaatgata
    14341 cgcactgcaa tttcaccacg attagcaatt aagatttttt taaacataag ggtttcttcc
    14401 tccgcagaac aatcattctc attgcccaca ggcaaaggtt aatgttccac ttgctgctag
    14461 cttgccatca acttctgccc tggcttcaac gacagcaatg gtaccgcgac gcttgataaa
    14521 ggttgctgtc atcacaagtt gatcaccagg gacgacttgt tttttgaact tcactttatc
    14581 cattccagcg taaaagacca acttgccttt attttcttct tttgacaatt ctaagacacc
    14641 agctgtttga gccaaagctt ccataatcag aacacctggc atcacaggat agtgaggaaa
    14701 atgcccgtta aagaaaggct cattaatagt cacattttta atggcaacga tatggtcgtc
    14761 tgacacttct aacacacgat caaccaataa cattgggtag cgatgaggca aagccgcttg
    14821 aatttctcta atatccatca tttgatccgc accaatcctt gtccaaattc aatgacatct
    14881 tcatttgata ccaaaatttc tgtaatcaca ccatcacatg gcgctggcac ttcgttcatc
    14941 accttcatgg cttcgataat cacaagggtt tgtccttttt ttacagtatc tccgactgcc
    15001 acaaatggtg gcttgtcagg gctagctgca agataggcta caccgactaa aggactttca
    15061 acaatatcac cttctgctac aaaagattct gcttgtggtt gctcctctac aggaacatcc
    15121 ttaactgatg ctggactgga cgcttccgaa gcagttggat tcggaacaag ttgtacctgt
    15181 ggtacaggca cagcatgttc ttgatttgat gtcgatgcat tgaggtgttg ttcgttttta
    15241 ctaaagatta gctcaccttc atttgttttg aataaaaatt cacgtaggct tgaggtatca
    15301 aactgagcca tcaaatcttt gatttcttga atattcaacc tactcctccc aacatttgaa
    15361 agctaataca gcattatgac caccaaatcc aaaagtattt gaaatggcat agttgatagc
    15421 tgtttctttt ccttctccaa agatgacatt tgcttcgata tcctctgata aagcttgtgt
    15481 cccagccgtc atcggaacat agttatgacg catagcctcg atagtggcaa tagcttcaat
    15541 agcgcctgct gctccaagaa ggtgacccgt aaacgatttt gttgaagaca ccggaacatc
    15601 cttaccaaga acggctacaa ttgcttgact ttctcctttt tcattagctg gggttgaagt
    15661 tccgtgcgca ttgacataat taatagcact ggcttcaata ccagcttctt gtaaggctaa
    15721 gtggatggct ttacgagctc ctaatccctc aggatttgga gatgtcatat ggtaggcatc
    15781 gcaggtattt ccataaccca caatttctgc taagattgtc gccccgcgtt cttgcgcatg
    15841 ttctaggctt tctaaaacaa gcattcctga tccttctccc atgataaaac cattgcggtc
    15901 tttatcaaat ggaatagagc ttctgcttgg atcttcagtt gttgagagag ctgttaaact
    15961 ttggaagcca gcaatggcaa acttggttat ggccgcctct gacccaccaa ctatcatcac
    16021 atcttgagtc ccaaatttaa tggcacgaaa ggcatcccca atcgcatcat ttgaagaagc
    16081 gcaggcagta ttaattgatt tacatactcc ttgagctttt aaagacatgg cgacatttcc
    16141 tgcagccata tttggtagcg cttttggcaa cgtcattggc ttcacacgtt ttggtccttt
    16201 ttcatgtaag cgaatcactt gctcttcaat ctccgcaatt ccaccaatac ctgaagcaac
    16261 aataacgcca aatcgatcgg aatcaatcat ctcaatattt aaatcagcat gattaatagc
    16321 ctctttcgct gcgtaaagag cataaagaga atatctatcg aaacggttca aatctttttt
    16381 cacaaagtat ttgtcaaatg gaaaatcctg aatttcagca gcattcttga ccgcataatc
    16441 agtcgtgtca aatttagtaa taggaccaat accaatttgg ccagctttca gattgtccca
    16501 aaacgtttca ggatcatgcc cgattggaga tgttagacca taacctgtta ccactactct
    16561 tttaaatgtc atttcactac gtctccttat tgcattgtca taccgccatc aatagcgata
    16621 acttgtcccg taatataatc ttgttccacc aagaagcttg ctaagtgagc aacttcttga
    16681 gcttttccaa tacgttttat tgggatttga cttaagattt gctcttgcat tttttcagga
    16741 aggacacctg tcatgtcgga ctcgataaat cctggagcaa tagcattcac gcaaatgtta
    16801 cgagcagcaa cttcacgggc aacagacttg gtaaaaccaa tcattcctgc cttagaagcg
    16861 gcatagtttg cttgcccaat attgcctgtt aaaccaacca cactagagac attaataatt
    16921 gctccttggc gggccttgat cattggtttt aacactgatt gagtcatgtt aaaagcaccg
    16981 gtcaaattga ttttcaagac gcgctcaaaa tcctcttccg tcattttaag catcaattta
    17041 tcattagtaa tgccagcatt gttaactaaa acatcaatcg aacctaaact ttcgatagct
    17101 tcattgacca tacgtttagc ttctgatgct tctgaaacat ccccagagat ggtaacaact
    17161 gtaacgccgt agtcagtaaa actagcaaca agctcctcag agatagcaga gcgaccattt
    17221 aagacaatat tagctcctaa actggcgaat tgatgagcca ttgctaaacc gatacctctc
    17281 gttgagcctg tgataaatat attttttcct ttaatttcca tgaatgtcct ctctatctaa
    17341 aaataaacgt aagcttacca tgttttcaac actagtacat agtaaatttt tatcaatttt
    17401 cttcacaaaa cctgtcaaaa ccttacctgg tcctacctca atgaattgtg ttatgccact
    17461 ttctactaaa gtcgcaacac tgtcataaaa acgaacaggc tccatgactt gacgggctaa
    17521 tagttctggg atacggtctt tttccataat attagcttcg gtattaccaa ccaaaggaat
    17581 cttgaagtca ctgaagttgt atctttccaa ctctttagcc aacaagcggc tagctggttc
    17641 taacaaagca gtgtggaaag gacctgacac gtttaaaggg attaaacgct taactcccct
    17701 ttcctttaaa agttcaactg ccacgttcac agcatctgtc tgaccaccaa ttacaatttg
    17761 actaggagta ttatagtttg ctggagcaac cacttcatgt ttagcagcta tttgacagac
    17821 ttcttcgatg acttgcacgt ctgtattcat aacggcaacc atctttccag atccttgtgg
    17881 tgctgcttcc tccatcaagc gccctctctt agctactaag gatagggtat cttcaaaaga
    17941 gagtgcccct gatgctacca aagctgagta ctctcctaag gaaagaccag ctaccatatc
    18001 cggtttaacg tgatgtaagc ccaaaacacg gtaaatagca attgatgatg tcaaaatagc
    18061 tggttgcgta tagctagttt gattaagttt taactcgtca ctatcaatca aacggcgcaa
    18121 atcgtatccc aatacttgac tagcttgatc aaaggttttt cttacaatag caaagttatc
    18181 ataaaaatcc cttgccatcc ctaatttttg ggcaccttga ccggcaaata aaaaggctgt
    18241 ctttgtcatt atcattatcc ttcatgtgtt tatctacttt tctattgaaa cagattgcca
    18301 gcgcttagct tcattttgaa taacacgagc tgcaccataa taaatatctt ttaaaatcgt
    18361 ttcacagctt tcttcttttc tcacaagccc tgcaatttgg ccagccataa cagatccatt
    18421 gactacatcg ccttcaataa cagcatgtcg aagcgatcct gctcccattt cttcaatatc
    18481 agtagctgtt ttttgaccaa ttaaaaatgc tttttctgct ttagcgtaag ctgaggtcaa
    18541 tttattttta atagaacgga cagggtggcc cacaacctgc gcagaaatca ccgtatcaat
    18601 atcttttgct gctaagattt tatctttaaa attttggtgg gcattggatt ctttagcaac
    18661 aacaaagcga gttccaattt gaacagcctc tgctcctaac ataaatgctg ctgctgcacc
    18721 atgaccatca gctataccac ctgccgcaat gacaggaatc gaaaccgctt caacaacttg
    18781 tcttactaaa gacatagtcg ttaacttgcc aatatgtcct ccagcttcca taccctcagc
    18841 aatcactgca tctaccccaa gcttttccat acgtttggct agcgcaacgc ttgggacaac
    18901 aggaacaacg attatacccg cctggtgcag tctttccata tactttcctg gatttcctgc
    18961 gcctgttgtt actactttaa caccttcttc aatgaccaaa tcaacgatat catcagcaaa
    19021 aggagataaa agcatgatat taaccccaaa aggtctatca gtaatagctt tgacacgatc
    19081 aatattagct ttaacgactt ctttgggagc attgccacca cctataatgc ctaaaccacc
    19141 agcattagaa actgcacctg ctaaatcacc atccgcgacc caagccattc ctccttgaaa
    19201 aatggggtaa tcaatattaa gtaattctgt aatacgtgtt ttcataataa ctttctataa
    19261 aaaataagga gaataatttg ataatcaaac tattatagta agaagaaaga gcgagctaga
    19321 tcctaaaaag agtctaatcc caccctaatg gtttgattaa tacttattgt tttttttagt
    19381 gatgaacatg aacataacag cagtaagctt ttcatagact tctgatgtta cttgtcactt
    19441 ttatccttat tttgactttt cctcaacgta agcaacaagg tcaccaacag tatttaatcc
    19501 ttcttctgtt tcaatttgaa tatcaaaagc atcttcaatt tctgaaataa cttggaaaac
    19561 atcaagtgaa tctgcatcta aatcatcaaa tgtagtttct agtgttactt cttctgtctc
    19621 cttaccaagt tcttcaacaa taatttcttg tactttttca aatactgcca tgtttatttc
    19681 tccttaaaaa atataaattt gtttttataa atgtgctagg cacatgaata actagatttt
    19741 aacaattaga cttccccatg tcaaacctcc accaaaaccg gaaagtaaga ttttttgggt
    19801 accatctaac ctaatctgtc ccttttgaac agcctctgac aagaggattg ggatactagc
    19861 agcactagta ttaccataac gcatcatgtt ttcaaggaat ttttcccgag gaacatcaat
    19921 cttgcgtgct attttatcaa gtatacgacg attagcttga tgcaataaac aatagtctat
    19981 gtcatctttt gtaatatctg attgcgccat tagtgtgagg atgctttttg acacatccct
    20041 aatcgcaaaa tcaaatatgg cacgtccatc catctgaata gtcgctatgg cttttttgcc
    20101 aattgagtac ggagatgaaa gactagtttc tcctgaaatt aaactctgac atctcgcacc
    20161 atctgtgtgt aatgtttccg ctaaaacatg tttatcttta ctggcttcca gtagcacgcc
    20221 accagctccg tctccaaaaa gaacggctgt cgctcgatcc tgccagttta ctaacttaga
    20281 taaagtctct gcacctatta ccattccgtt ttggtaggca cctgatgcaa taagcttatc
    20341 tgccatagcc aaggcaaaga caaagccact acaagcagca gtcatatcaa aagcaaaagc
    20401 acttgtagcc gcaatagctg cttgaacttt cgcagctgtt gatggcatag tggcatcagg
    20461 gctgatagtt gcaacaataa taaaatcaat agcatcagct tttaacccag actgagttaa
    20521 aagctgatca gcaacctgaa tagctaggtc actagtcatt tcatctctag aaatatggcg
    20581 ttctgctatt cctgttcgag aaaagatcca ctcatgacta gtgtccatta tgctagctaa
    20641 atcattatta gtcactaact gctgtggaac atagtgggct acctgactga ttttagaaaa
    20701 aatcatttaa accaaatcct ccaaaaattg atgtagattc cctagtccac gcaccaatgc
    20761 ctgcatctct tcatcactca tatcagcaat gacatgtcca accatatttt tatggaactt
    20821 tgcatggagg cggtccaaaa gtcgacccct ttttgttaat gacaggtaaa caactcgcct
    20881 atctgagcgt gatcgcgttc ttgcgatata accttttgct tctaatttat ttaagctagt
    20941 cgttactgtc cctaacgtta ccattaattc tctggcgata tcacttggag tcacctgatc
    21001 atatttgccg ataatttcaa tagtgtgcat ctcttttaaa gagacatcat taaattgact
    21061 ggtttttaaa ctcatttctt caattaccaa aatacggttg aagatatcaa ccaagtagtg
    21121 attgattttg tcatattcca agcaaatacc tcctaacaat aaaactttga cagtcaaatt
    21181 atatcagagt taaaagcact ttgcaagcat gagtctactt accttgaaaa tttggtcggc
    21241 gcctttctcc aaaagctatg acaccttctt taaaatcttc cttgaaagct agctcctctt
    21301 gaatagcaag ctctgcctta gcataatctt cccatcctgt gaaaaagctt tgccagacca
    21361 atgatttcat tccagcataa gaatttgaag agccacgtct caatcgcttt aaaagttgaa
    21421 gacaaacttt gtctagttta tcagattctg ccgtacggta gacaaaccca taatcgacac
    21481 ccttatcagc agtaattcct tcacctgtca tcacaagatg agttgcacga ttaagtccta
    21541 ctgcacgagt caatagaaat aaaccaccgg catccggtgc tagtccaaca tttacaaaag
    21601 cttggataaa ttttgtttga gtactagcga tacaaaagtc aacagctaaa gctatattaa
    21661 aagccgctcc agctacagct ccatcggcgc aaaggatgac tggttttggc aaatgcttga
    21721 ttgcaaaaga aatttcttgt accagttcag caatcttgac tagcgactgc acattatctt
    21781 ttgcaacagc ttcttgcatt tcaactaggt caccaccaac tgaaaacact tttccaacgg
    21841 ctttaattag taaaaaacgc acagatgtat cgcgtttaac ttctgctaat gctaccagaa
    21901 tctcttgaca aattggaata ttaaaaccgt ttgaaacctc tggacggttt aaagtcaata
    21961 tcgcaagatc atctacaaca tcaaagatga tgtgtttaaa ctgcataaca atcctctttt
    22021 ctgataattt atttgactaa gaaattattt ctctttaaaa tcatttgata atcaaatcaa
    22081 ttacctaatt atgatatact aaataaacca ttttgacaag agaaaaaaac gatatctata
    22141 aaagaaaacg ttttctctaa ctgttttgac ataaaaaaaa acgtataact tcgggaaaat
    22201 tatcctgaga ttatacgttt gacatcttta aatatcctct aaggcatctt tcactttatc
    22261 aaaaaaacct tttttctttg gatgtaacat tttttcacca ctcgcttctg caaatgcttg
    22321 caaggcttcc ctttgagcgt cattgagttt ggttggggtc acaatattaa cggtaacatg
    22381 ttgatcccct tgacctccac cacggagttt tggtgctcct ttgcctttga ggcggaaggt
    22441 tttacctgtt tgtgtcccag cagggatagc catctcaaca tcgccatgaa ccgttggaat
    22501 ttcaacagta tctcctaagg ctgcttgagt aaaagaaata tctaagctgt agtaaatagt
    22561 ggaaccattg cgttcaaatt gcttacttgg taagacattc aaaataacaa ataaatcacc
    22621 ataaggtccg ccattaaagc cagcttctcc ttgaccttgt aaacggattt gctgaccagt
    22681 ctctacacca gctggaatct taacagacac tttatgagct tgcttttcat gactagtacc
    22741 atgacaggtt tgacagggtt ctttaatttc cttaccacta ccatgacaaa tatcgcaggt
    22801 gacttgtcga cgcatcatac caagtggtgt ttgggtgtca attgtcatta cacctgaacc
    22861 atggcactta cgacaagtta ctggagcggt accaggtttt gcacctgagc ctaaacaagt
    22921 gccgcaggtt gcttcgcgat tatagctaac ttctttttca acaccaaata cagcctcttc
    22981 aaaagataaa ttaacacgat attgcaaatc gtcaccttga cgaggggcat ttgggtttcg
    23041 gcttccaccg ccaccaaaga agcttgagaa gatatcttca aaaccaccaa agccacctcc
    23101 gtcaaaacca ccaaagccgc ctgctccgcc accaaagccg ccttgagcac ctgcagcgcc
    23161 gtattgatca taagcagcac gcttttgtga atcacttaag gtttcgtaag cttcttgaac
    23221 atccttatac ttttgctccg ctccagcttc tttattgata tctggatgat attttttaga
    23281 catttttcga taagcttttt tgatatcgtc ctgagaagcg tccttagaaa cccccagacg
    23341 atcgtaatat tctgtattgt tcataatgta agataccaag ccgtaaaacg actcaatgaa
    23401 aaataggaaa tccgacaaag atactctcgt atctaggagg tatttctctt ttttcgcagg
    23461 gtcgtaggcg tgttcaaatc cgcaaaagag tctttacacg ctttagcctg tgttcgaata
    23521 atcgaacttg tattcctttc ttaaaatatt ttgacgtcag catttttaca ttttatttag
    23581 ccaaaaacag aggtttggta caacctctga attcggatat taatgttact agataactaa
    23641 atcattactt ttctgtaaat tcgccatcta caacatcatc attatttgct gaatcattag
    23701 cttgtgcacc ttctgcacct tgtgctgctt gttgagctgc tgcagcttgc tcgtacattt
    23761 taacagccaa agcttgcgct ttttcattta atgcttcaag tttagctttc atgtcgtcaa
    23821 ggttgccaga ttcttgcgca gcttttaact cgtcaagagc tgattgcgct gcatcgcgtt
    23881 ctgtatcaaa gcctttacct tcagtttctt tgattgtttt ttcagtagca aagatagctt
    23941 ggtcaacttc gtttttaagg tcaacttctt ctttacgttt cgcatcggct tcggcattag
    24001 cttcagcgtc tttcatcatg cgatcaattt cttcttcaga aagtccgtcg tttgatttga
    24061 taacgatgtg ttgttccttt tgcgtaccaa ggtctttagc ttttacagaa acaataccgt
    24121 ttttatcgat atcaaatgtt acttcaattt gtgggattcc acgaggtgca gctgggatat
    24181 cagtcaattg gaagcgacca agagtcttgt tatctgctgc cattgggcgt tcaccttgaa
    24241 gaacatggat atcaacagct ggttggttgt ctgctgctgt tgagaagact tgtgatttag
    24301 atgttgggat agtggtgttg cggtcgatca atttggtgaa gacaccaccc attgtttcaa
    24361 taccaagtga caatggtgtt acgtcaagaa ggacaacgtc tttcacatcc ccagtgataa
    24421 caccaccttg gatagcagca cccatagcaa ccacttcatc agggtttaca gatttatttg
    24481 gttctttacc agtttcagct tttacagctt cgacaactgc tgggatacga gttgatccac
    24541 caacaaggat aacttcatca atttctgaca atgacaatct tgcatctgaa agggcttgac
    24601 gaactggagt tttcgtacgt tctacaaggt cgcgagtgag atcgtcaaat ttagcacgag
    24661 ataagctcat ctccaagtga agaggaccgg cagaaccagc agtgatgaac ggtaatgaaa
    24721 tttgtgtttg tgtcacacct gaaagatctt ttttagcttt ttcagcagca tctttcaagc
    24781 gttgaagtgc catcttatct tgtgataagt caatgccatt ttctttctta aattcagcca
    24841 ctaagaaatc aataattttt tggtcaaagt cgtcaccacc aagtttgtta tcacctgctg
    24901 ttgcaagaac gtcgaagaca ccatcaccta attcaaggat tgatacgtca aatgtaccac
    24961 caccaaggtc aaaaactaag attttttcat ccttgtcagt cttgtccata ccataagcaa
    25021 gtgcggctgc tgttggttcg ttaacgatac gttctacttc aagacctgca attttaccag
    25081 cgtctttagt tgcctgacgt tgtgcatcgt tgaagtaagc tggaacagta ataactgctt
    25141 tttctacttt ttctccaaga tagtcttcag cataaccttt aaggtattga agaatcattg
    25201 ctgaaatttc ttgaggagta tattctttac catttgcaga aactttttca gaagttccca
    25261 tctttgattt gatagagata acagtatctg gatttgttac cgcttgacgt tttgcagcat
    25321 cacccacgat aatttcacca tttttgaatg atactactga aggagttgta cgattgcctt
    25381 ctgggttagc aatgattttt gattcagtcc cttcaagaac tgctactgct gagtttgttg
    25441 tacctaagtc aataccaata attttagaca tgttaatacc tcttatttta taatacttta
    25501 ttacttttta tttcaattta tcttagtaag cactcgaatt attttacttc caattctaag
    25561 caatcactat agtttaatca gcaagttgaa tagcttctaa cttgctatct agtttactgt
    25621 cattacggac aaaaacgaaa actcatttac cttagttata aacaactacc atcgctggtc
    25681 ttagcagacg ctcgtgcaat ttatatccct tttgaaagac ttctgcaatg ctatcggctg
    25741 gatgttcatc atcggctggg agggtctgaa ctgccatatg aaagttgtgg tcaaatgagt
    25801 cgacttctac ttcttctacg ccttcttctt ttaatgcttg aataaggcta tcacgagtca
    25861 tttctaaacc ttttttaaca tcatctgtca acccttcaac agccaaggcg cgttctagat
    25921 tgtcaagcga tggtaagatt gcttttgcca gatcctgaga acgatagcgt tgaagttgtt
    25981 gacgttcttc actagagcga cgctgtatat tctgcatttc tgcatgagct cgcaagtatt
    26041 tattttcaaa ctcatcagca cgttcgttta caagttctaa ctctgatttt tcaggagttt
    26101 cttcaataac ttcctcaact gtctcttcag tttcagtggc ttccacttct tcttgtaaat
    26161 cgtctttttt aatttcttct gacactgagt gcctcctttt aaataactta ttgaatactg
    26221 ccattatcag tgaacttcat aatggttaga atttaggtat cgataataat cacctaattt
    26281 agcagccaat acctttccaa taatgtttac caaactaaca gacctacgat aatccatatc
    26341 aataggacca attaaactca ggagtccaaa cccacggtaa ggaatcaaaa atttgtgagt
    26401 taaaactgac acatctgcaa gtgcggcttc ttgactatct gccacttgga cagaagccat
    26461 ctcaccttct ttcagacttt gcctcaaaga aattgctact tgctgttcat tatccaaaaa
    26521 ctgatacgtt gatagatctg aatacgttaa agaatttacc ttgccagcaa caaataccgt
    26581 ttccaaaaac agctctgaaa aaacataatc aaatagttgt aaaacattat ccgtagtcac
    26641 aaaatacttt tgaacgatct gaggaatttc tgtcctcaac ttataatgaa tatctatgac
    26701 actattatcc agcaagcgct cctctacgat agctttaaat gctatcaagt cacgtgtcaa
    26761 aaagtttctt ggaatagcaa actgcactgt cactggctta gattcatcta aagtcatgac
    26821 tgctagagca tcatggttgc taagctgaac aacatcaaac cctgttaaac gttgacgagc
    26881 tggctccaca tctaaaataa cggatgtata gcccgtcatc tccgctaaaa tgtgactagc
    26941 tttttgaagc atgtcttcta atttgaatgc ttcaaaatca aaagctttta tgacatgata
    27001 aatatcttgc tcatcaatac tatctagcct gagggagtgc tctacaaaat acttaaaacc
    27061 agctggactt ggcatccgtc cactagaagt gtgcgctttt tccaacaatc ccaacttctc
    27121 tagttttgcc atatcattac gaatagtggc gctactagaa tcaatcgttc tctgtaaagc
    27181 tttagaccct actggttcat gagtttgtgt aaatagctca acgattaaat tcaaaatatc
    27241 attttgacgt tgtgtaatca caaaccaacc actccctttc gtttagcact ctatttagta
    27301 gactgctaat ttataattct attatactct ttatgggaga catgtcaaaa aaaaaaactc
    27361 aaaaaaatta gcactctttt ataaagagtg ctaatttcag tcatagtttg ttaaatcgtt
    27421 actttcaatg acctgaatta gtcgcctagc ataggtttta tcagtataat gcaaatactt
    27481 ttgtaaactt ttagctggtg ctttataccc tttttctgta gcaagattac gatacaaacg
    27541 cttatcgact tctttgccct gccgaagcat tcgtaaataa tctctaattg cactagcatc
    27601 atctttataa atagcatatc tcacgttttg gttggtttgt ttaggggact ttagggtaat
    27661 ggctgcttgt cctggagttg ctttcttgct aaaaagatta tgatacttag acgctagtaa
    27721 tgtttttcca tcatgggttt ccaaaagaat ttgagcaatc aaaatagatg gtctaatgcc
    27781 ataatatttt gccaatggtt taacttcttt acccattttt gtaataaatt gtttttggct
    27841 gtagttcacc cttacttctt tatctgcact agctatcctt tggctactca gcaaaggaca
    27901 aacaatcagc aataaaaagc aagctagaag cgttaaaaaa tacggaaact ttagtcgttt
    27961 tctcatcgtt tctcctttaa agcagcaatg tactcttcca acgttaggtt gtgctgagcc
    28021 atataacgag cagacgcctt acctacatag cggtaatgcc aatcctcata atcaacccct
    28081 gtactagtct tttttccttc tggaaagcgc aagacaaacc cataatcagg tgcaattttt
    28141 tgaactgctt tagctactga tggatcactg gcatttaaag tatctacagt gctcatgtca
    28201 atagcaagac cagtgtgatg ttcactagtc cctggcggct gtgaataggt ttgcaccaaa
    28261 gcctccgcag cttcttgtgt caatgttgga tcgttagcca tctctttttt aatataagat
    28321 tggtaaagct ctgtttggta gtctacggaa cggtacccag agataagatg ttcttgcgag
    28381 tcgatagctt gtgctgctgc taaaaagtca ctagtggctt gctcaatgcg tttatccaca
    28441 gaaataccat taatgtcagc taattcagga ctcatttctt ttgtaatgtg atcgcggttt
    28501 actaaaacca actcccaatc ttcaacagat accttaggta aagctcgtaa acggtccgtt
    28561 tttttgatat ctttttgttg gatttctttt ttattcaact gagttggtgt tactgactct
    28621 tctggtttta taaagaggta aagccctcct aaaaaaacaa taacaattag caattgcact
    28681 aaatagttta acgaattata tttcatctga ccgttcttct attatttcac gaccgcggta
    28741 gcggtaactc atatctccaa tagtctttat cgtaaattgg ccatcatcaa attcaacaac
    28801 tgtaacactc ccattatcaa tatactgttt gtctcgatct ggatcaatca accacagaaa
    28861 cgttccaatt gtcataccat ggctaaccac aagagcattt ccgccgccag cattttgaat
    28921 ggacaaggca atagcttcaa acccctccca aatgcgctta cgaagaactt cccatggttc
    28981 tgcccaatta gcggtatcta tttccacgat gctttctgcc agttcagaat agggaacatc
    29041 acgtaggtta tcacgatttt caaaggcttt tgttcttgga aggacaccta gaaataattc
    29101 tgaatcataa gtcccttcta gactcccaaa acaccactca cgaatacgat tatctttagt
    29161 ataaggcaaa aattcgtttt ctgattctct taaaataatt tctattgtct gcatggttcg
    29221 acctgaatca cttgaaaacg cagccttaaa tggtatagtt gcatctttta aacctaagcc
    29281 aagttctcga ataccttctt ctcctttttt tgtaagaggt gtgtcactcc aaccctgagc
    29341 gcgaccaatg gtattaaaca tcgtttttcc atgtctggca atatacaacc ttgtttttgt
    29401 catttcaacc tcctaaactg tcttattaat tattatagca tttaaagaaa acacttgcaa
    29461 aacacttcct gatggctatt tgagatcaaa tagaccactg acttattgtc tattttatta
    29521 aaaacaatgc tattgctaca attcaaatca tcacataaat ttccaaacga ttacattttt
    29581 gtgtttcgct caaatgtata taacaacaga cccacactac aactaaactg acgttacaaa
    29641 atgatgtcaa aacagtaaca aaatctaact atttgtcaag aaaacgatat taaattttca
    29701 cacaactatc ttataatgag gatgcaacca ataaaaagat aagacatttt atgttgcaaa
    29761 aaaggctgct tggaaacttc catgcagcct ttttttaata cctttttcca aaaatagctg
    29821 aaacaagtac aattacaatt gctgctccca aaatggacgg gaaaatagcc atacctgcca
    29881 actgaattcc ccaatcccca aaaagccttt gcccaacagc tgaccctatg agacctgcga
    29941 taatattagt aaaacaaccc atggactggc ttttttcagt cattttacct gctatcatgc
    30001 cgataaaggc acctacaatt aaagaccata tcatcgttaa cacctccttt cttgtaaaat
    30061 ccttttagaa gaactgctat ccattaaatg ttcttaactt tagttgattc ctttaccttc
    30121 ttctttagta agtgtttccg tgcctgagta aaatagaaaa aacaattcct tctattaaga
    30181 tagatagacc gagaacgact agaagtcttc acacactaaa taacttaaca aactttatca
    30241 cacagctaat cgctaataat agtgtagaca aacgtgatgg ttcattaaat acccgtcaga
    30301 aactcctgaa ggttctaaag caatacctgt cagtcttatt ttagcataga tgatggtctt
    30361 tttatagacg gtcactaaca tgacatacaa aaaggcagcc tgtgaaagac cgaccgcctt
    30421 tttttcagag acaaaatact ttaacttatt gctatcagca actatcaatc tcgcaatttt
    30481 tgcaattctt gtgctaataa ttgttgagcg acttgtggat tagcttgacc tttggttgcc
    30541 ttcatcaaga agcctgtgaa agccttatca gcattacgtt tgcctgattt gaaatcagcc
    30601 actgcagctt cattatcagc aaagacttgg tgaataattg gtaccaaaac agcgggatca
    30661 gaaatctgaa caagtcctgc cttttcgacg taggcgcgag ctgagccacc atttttagcc
    30721 aaatgcacaa agaccttctt agccatttta gaagagattg taccatcagc aatgatagca
    30781 atcatctcca ccaaattttc tggtgtcaga gcgatttctt caatggtttt gccttctgca
    30841 tttaagaatt gggcaacttc tccttgcaac cagttagaga cttgcttggc atcgccacca
    30901 agacttactg cagtttcaaa gtaatctgac aagactttgg tagctgttag ctggctagca
    30961 tcataagctg agagaccaag ttcctcttcg tatttagcac gacgttgagc tgggaattga
    31021 ggtaattgag cacgcatctc gtcaatccaa gcatcatcaa tctcatacaa gggtaggtct
    31081 ggttctggga aataacgata gtccgctgcc ccttctttga cccgcatcaa aatagtcccc
    31141 ttattcgctt cgtcatagcg gcgcgtttct tggcgtatca ccccacctga acgcaagagt
    31201 ttggcttgac gttccacctc aaattcaagc cctttacgga catttgagaa ggagttcaag
    31261 tttttcaatt cagtctttgt tccaaattgt tcttgcccgt aaggacgaag ggaaatattg
    31321 gcatccaccc gcatagagcc ttcttccatc ttgacgtcag aaatacccgt atactggatg
    31381 atttctttca gagctgtcaa ataagcatag gcttcttcag gagaacgcat gtcggcttct
    31441 gacacaatct caatcaaagg aactccttgg cggttaaggt ctacataaga ataaccatct
    31501 gtgccgtgag tgtttttacc agcatcttct tccaagtgtg cgcgttcaat acgaattttc
    31561 ttggttgaac cgtcttccaa tttaatctta atccatccgt tgtagccaat cggctcatca
    31621 aactgtgaaa tttgataagc tttaggatta tctgggtaga aataattttt gcggtcaaag
    31681 tgcatctctt tatggatgtc catattgagg gcaagcgcag cttttatgcc cgcatcaata
    31741 acgcctttgt tcatgactgg taagacccct ggaaaagacc aatcaatcac attcgtgttg
    31801 gcatttgggt cctcaccaaa gtgagctgac gaaggtgaga aaattttgga attggtattt
    31861 aattccacat ggacttcaag cccaataatg gtttcaaaat tcattacttg tcacctccaa
    31921 aaataatcgg ttgttgcttg tgataatctg tcaccgcttc aaaggctgct gccgcttgat
    31981 agatggtttc ttcagcgtat ttcggaccaa ttaattgaag ccctactggc aagccatcga
    32041 cgaatcctgc tggaatggaa attcctggca gaccagccaa gttaactgga atggtcaata
    32101 agtcggccaa atacatggca acaggatcgt ggttgagtgt gtctaagcca aaagcaaccg
    32161 ccggtgttgt tgggcctaaa ataagatcat aatccgcaaa gaccttgtca aaatcttcaa
    32221 taatcaaggt acgcacttga ccggcctttt tgaaataagc gtcataataa cctgatgaca
    32281 aactaaaggt cccaagcatg atacgacgtt taacctcatc accaaagcct tggctacgag
    32341 tgttaacata gatttcatcc aagtttttag catcgtcagc acggaaacca tagcgaatgc
    32401 catcaaaacg ttgtaagttt gaggacgctt ctgacgaagc aataatgtaa tagacagcca
    32461 caccatattt gctatgtgga agactaactt cctcaacagt agctcctaag gcttcaaatt
    32521 gtttagctgc cgcaagaacc gtttccttaa tcttaggatc aatcccttcg ccaagatact
    32581 ctttaggaaa ggcaatcttc atgcctttaa tgtcacgacc aatcttagat gtgtagtctg
    32641 caatgcggac aggcgctgaa gtagcatcct tgacatcgct acttgcaatc acatttaata
    32701 attgggcgtt ttctttaact gtcggagcaa aaggtccaat ctgatcaagt gaacttccaa
    32761 aagcaatgag accatagcga gaaacagtgc cataggttgg tttcaaaccg acaacaccat
    32821 taaatgcagc tggctgccga atagaaccac cagtgtctga accaagagat aaacggactt
    32881 gtcctgaagc gactgctgtt gccgaaccac ctgatgagcc accaggtact tttgtgtggt
    32941 cccaagcatt tttcgttttc ttgaaataag aggtttctgt tgaaccaccc atggcaaatt
    33001 cgtccatgtt ggtttttcca atgacaatca tgtctttagc gtaggcattt gctactgatg
    33061 tggcatcaaa aatcggctcg tagttataca acatttttga agcggctgtg gttaggatgc
    33121 ccttggttga gatattatcc ttaacagcta gtggaatacc cgacatgagg ttatcagcat
    33181 caataccttt ggcatcgatt gccgcagctt gtttaagagc agcttcttct gaaacagtga
    33241 taaacgaccc gacagcctcc tcacgagact tgatatcttc aagtgttttt tgagtcaatt
    33301 cggttgcgga aatctcctta gctacaagga ggtcatgcaa ctcttcaatg gttttatgat
    33361 taaaagacat taggcatctc ctccgtcatc caaaatagca ggtaccttga taaagtgatt
    33421 ttctttttca ggaacatttt taaagagcaa ggcacggtct gttccttctt cagcgacatc
    33481 ttgacgcatc acatttttct tatctgccat ggttgttgta atggcaacac cttcggtatc
    33541 aacttcgttc agcaattcaa ccatgtcaac gattttagat agggtcgttg caaaggttgt
    33601 tgtctcactt tctgaaaatg ataattttga tagtttcgcg acatggcgaa cttcttcttc
    33661 agaaattttc atgatttctc ccatccaaga tgacaagaag tattccaatt ccaaagaaca
    33721 gctctgctat tctccaaagg tagcggaaaa actcctcaca tcatttttac atagtctcaa
    33781 tcattatatc ataattgcgc ccatttgcca taggtgacta atgcaattct agaaagccat
    33841 atagcaaaaa acttcctgac taaggtcaga aaaccttagt caggaagtgt gacaaactaa
    33901 actctattta tcttgagtaa gactgtggcc tgaagctttg atggcagcct gagcagccgc
    33961 taagcgagta agcggcactc taaatggcga acaagaaacg taggtcaggc cttggctgtg
    34021 gcaaaaggca atggaagcag gatcgccacc atgttcccca caaataccaa gtttcaactc
    34081 aggcttaacc gaacgggcta aagagacggc caatcccttt ctgatcaaag gtctggaacg
    34141 gttccttatc aaaaaatacc cctgtcaacg tattcttcca agtattttcc tacaacatca
    34201 cagaaaaagt aacgttcttt caagtcggta atatgtttac gaaggtaata aaggggtgct
    34261 ttattctaat ttaccaaatc ctcaacgatt gtgacaacat gtgatgtgat aagcctaaga
    34321 taaaaatggt acagactcta gcattcaaga gtttgaagct ttatttatat tctaatgctg
    34381 aaaagactag agtttgtcta atggctgtga gacgatcctc taaaccatca actcaaatca
    34441 tttctcaaac agctaaaatc ctgtctcctt caaaaaaaca tgtgttctat ctgacacagt
    34501 ccaaagttta gttgcctttt agacagcaca agaatcatca ggactaattc tgaccagcat
    34561 gtcacatacc tcatctacct aacccataca tacagtaaaa ccacatagag caatgattac
    34621 ggttaccaaa ctcttagtca ctgaatcaat agtttggtag gctcttttag taatcgttaa
    34681 taagcttagc accaagaacc tgctcaaagt gagccaaaga ccactcataa gattcttttg
    34741 taaggctagc gacagccgat ttaacaatct ctaattgata accaagatga taagcgtcaa
    34801 tagcagtatg taagacacag atatcagata aaactcctgt taacactaat tgagtgatac
    34861 ctctttctcg tagtctaata tctaaatcag tccccgaaaa agctgaataa taacgcttat
    34921 caatccaaaa aactctggga tgttgcttca tataactgta aacttcagct agtggaccat
    34981 aaagatggcg tccagtagtt cctttgatat tatgtgctgc aaataactta ctctcaggat
    35041 gccaaggatc attttgatca tgacaatcaa tagcaaaaaa aatatagtct ccttgatcaa
    35101 atgccgtttt agttacctct gctattttag tggcaatagc ctgagcagat ttacctgcac
    35161 ttaatttacc atcatctgct acaaaatcat ttgtgtaatc aattgaaatc aatgctctca
    35221 tcactctctc ctaaacaggg aaacctctcc ccttatctct tatatatggc attgtatcag
    35281 tttttattac aggtatcaag acatctattt gcatctacca ttaacagcaa aaaacatctc
    35341 ttttcaagag atgttgtctt tttctattta aaattctttt aatttagcaa aaataccttc
    35401 gttgataact ttgaggtatg tccctttcat accaagagaa cgactttcaa taatccctgc
    35461 actttctaat ttacgcagag cattgacaat aacagaacgg gtaataccaa tacgatcagc
    35521 aataacagaa gctgtcaatc gtccttcgtt accatctaac tctctaagaa ttgctgcaac
    35581 agctttcatt tctgaataag aaagcgtatt aattgccatg ttgaccgctg tttgtttacg
    35641 gatggtgtct tctaagtttt ctgtctgaag atttaatagt tgaatcccca caacagtact
    35701 tgagatctca accaaaatca aatcatcatc actaaactca ttgtcattac gccagataat
    35761 gagtgatcca aggcgcatcc ctccaccata aatcggcgca atagtcgtta gacctcctgg
    35821 ataagtgtct ttagactcaa cagggaatat agtcaattca ttttcgacag aaaggttagc
    35881 ttctgtatcg taaactcggc tagcagcctt tacataagta tctggaaatt gtttagcttc
    35941 aaaaaattcc tcaacacgat cagtgttagt tttatatttc atggcataac caagcagtgt
    36001 gccgccgcca ttgataatac aagcattgca gtcaatgata tctgctaggc gagatgccat
    36061 tgtgttatac ggtaattctg tttctaggct atctacggaa cgctgcaaaa tagatgtgat
    36121 tttacgagtt ttttctaata agttaggcat ttttttcctt ttcctttgaa ttatttgcgc
    36181 tttcattata acaaagctaa ctcgcttttg caaggaatta tcagaaaatt ttctattctt
    36241 actacaattc caactattga tgccttatta tcacttcatt taaaggagat aagcactagc
    36301 ttgttagagc atagggtcac attcttttaa gaaacgttat ttttattaat caaagatgag
    36361 cattgcatta acgtctatac tggtataaga cacgtgtaat cttttcttgg acatcttcta
    36421 attcttctac acttggtagg taaacaatac ggaagtgatc tggatctttc cagttaaaac
    36481 cacgtccatg taccaacatc actttttctt gctttaataa ctgtaagaca aattcttcat
    36541 catcatcaat acgatacatc tgacgatcaa ttttcggaaa taaataaaga cctgcctcag
    36601 gtttaactgc cgataagcca gggatagcat taatagcttc ataaataaaa ttacgttgct
    36661 caaaaatacg ccctcctggc agtaacagtg catcaactga ttgatgacct cctaaggaag
    36721 tttgaacaac ttgttgggct aaaacattgg agcataaccg catattggca agcatgttta
    36781 acccttcaat gtaaccttta acatggtctt taggacctga taagaccatc catccaacac
    36841 gaaaaccagc aatacgatga gatttggaaa ggccattcat agatacacaa aaaacatcag
    36901 gtgccaaact tgcaatagca atatgctctt tactatccat caccaaacga tcatagattt
    36961 catcggcaaa aataatcagc tggtgttctc ttgccaaagc aacgatgtct tctaaaatct
    37021 ccttaggata aagagctcct gttgggttat taggattgat gaccacaata gctttggtgc
    37081 gactcgtgat ttttgatttg atatcagcaa tatcaggata ccaaccagct tcttcatcac
    37141 aaagataatg gaccgctttt cctccaccaa gactcacaca agccgtccat aaaggataat
    37201 ccggcattgg tactaaaact tcatcgccat tatctagcaa agcttgaagg gacatggata
    37261 tcaactctga cacgccattt cccaaataaa tatcttcaat gtcaacatct gggaagccct
    37321 tgagttgaca atattgcatg atagccttac gcgctgaaaa aatcccttta ctgtcagaat
    37381 agccctcact tagcctcgcg ttgacaatta aatcacgaat cacttcatct ggtgcttcaa
    37441 aaccaaaggc agcaggattg ccagtattta aacgcagaat tttttcacca ctcgcaatca
    37501 tgcgattagc ttcatccaaa acaggccctc gaatatcata ggcaacatgt tctaattttg
    37561 atgatttttc aataattttc atagtctcat acacctcgta ttccatatta taaaccaaaa
    37621 tacttaaaat agaaagaatt tatccatcaa agcttaggac agctaatcgt tttaacacag
    37681 gtcttatgag acgataatac agtctttagt ttagcaaaaa taatggatcg ctttcaaaat
    37741 gactcaaaaa agagtataat gaaaaaaaga ataaaagcta ttcttgtcaa actgttaaag
    37801 gaggacagtt ctatgtcact aaaatataaa cgtatcctcg ttgctattga tggctcttat
    37861 gagtctgaat tagctttcaa taaaggcgtt aacgtagcac tacgtaacga cgctacctta
    37921 ctactagtac acgttattga cacccgtgcc ttgcaaagcg tagctacttt tgatacttac
    37981 atctatgaaa aattagaaca agaagctaag gacgttttag atgattttga aaaacaagca
    38041 cagatagcag gaattacaaa caccaaacaa attattgaat ttggcaatcc caaaaactta
    38101 ctagctcacg acattccaga tcgtgagaac gctgatttaa ttatggtagg agctactggt
    38161 cttaatacct ttgaacgcct ccttattggc tcatcttctg agtacattat gcgacacgct
    38221 aagattgact tacttgtagt ccgagatagc actaaaacac tctagtctat tacaattttc
    38281 aaacaccaaa aaacaagcag catctacaac gaaattgctt gttttttggt gctgagctaa
    38341 gtctagtcaa tatcttttta tttcttgata tttaaaagag taaacctcta tttatcgaat
    38401 cgttgtagtg atttttgtaa ttgtttgtct aactcttttt ttatggctac ttcaggtgcg
    38461 tgacgctctt gccaatagtc aggtttttga attttatggg taacggggtc aaagtgtgcc
    38521 ttgccatctg gaaaaatttt agccatattt gcttcatgta ctgcttcaaa tataggttgt
    38581 ggatctactc ccatcagtac aaaagaacca taagtaaaat aaagcaaatc cgctaaggca
    38641 tcaacttgcc caatcagggg cgtttcaaca tgttttttag cttgtacctt attaactgct
    38701 tggtcaacag caccatgcaa atcgaaaata gcctgtgtaa attgttgttg gtctcccttg
    38761 cttgctgcgt aaagaaactc aacaatttct tctactttga agcctgacct ataaccagct
    38821 tctgaaatgg tataactacg cggtgtttca atagtatctg agtccatcag acgatgaaaa
    38881 tctttgactt tattaaaatt ttcatcacgg cttttaaagc tcttctctac atcaaaatgg
    38941 atgagaccgt agtgagctaa ggctttggaa atcccatcat tattattaga gtcggtagtg
    39001 aaatgggctc catcttttac cacagtttca gcatttccca tagcaatacc gataccaact
    39061 cctgataaca tttcaaggtc attatctgaa tctccaaaag ccatcacttc agacaagtca
    39121 aatccaaaca tctctcccaa acgttcaatt ccttttattt ttgattgatc aacagagatc
    39181 agatccaagg aataaggact acttcttgta atttttatat gagggaactt ctcttgtatt
    39241 ttcttagttt cagcttgtga cgctaccaga acaacctgat aaataggctc ccgcataata
    39301 gttactaaat ttctaaaact ctgaggcttg attcggcgaa tcaaatgctt aaaactaccc
    39361 tcaactgttc ttgcccaact tttgggcaca aaactactaa tgacttgtcc aaatgggcta
    39421 gtccccatat caataatacg cgatcctgct aatccagaag ctgttccaag agaaatttct
    39481 cgcttttttt cgttggcata gcgaatcact ttgtaaatca tcgactttgg caattgattc
    39541 tgatataaga ccttatctct tgttaagata tattgcccat tgtaagtaac ggcaaaatct
    39601 aatccaaaat tttctagaaa aggttgcaca aatcccggtc cacgaccagt tgctaaaccg
    39661 accataatgc cttgtttttt gagttgttgg atggcttttt gcgttgtttt ttggatattt
    39721 ttacgatcat tgagaagggt cccatcaata tcaaaaaaga ctgcttttac tgtcaaaacc
    39781 ttcttttgcc tcctgtgttt atgatagaat agattatatc ataaataaaa ggaagtttga
    39841 caatcaaatg aaaaaaatcc tagtcttaca cactggtgga accatttcta tgcaagctga
    39901 taactctggt agggttgttc caaatcaaga taatcctatg acgaaaatac atgctgcagc
    39961 ccaagatatt cagcttaccg ttagtgattt tctaaatctt ccgagtcctc acatcacgcc
    40021 tcaccacatg ttatctattt atcatcatat tcaagaaaga actgatgtct ttgatggtat
    40081 agtcatcaca catggaacag ataccttaga agaaacagct tattttttag ataccatggc
    40141 attgcctact aatatacctg ttgtcctaac aggtgctatg aggtcttcta atgaagttgg
    40201 tagtgatggc atatataatt accttaccgc acttagagtt gcaagtagtg ataaagctaa
    40261 agaaaaaggg gtacttgttg ttatgaacga tgaaatccat gctgctaaat atgttactaa
    40321 aacacataca accaatattt caactttcca aacacccaca cacggaccac ttggtatcat
    40381 catgaaaaat gacctacttt ttttcaaaac tgctgaacct cgtattcgtt ttgacttgag
    40441 atgcatttct ggaaccatcc ccattatcaa agcatacgca ggtatgggcg atggtagtat
    40501 cttgagtcta ttaactccag gtagcattca aggtctagtt atcgaagctc taggagcagg
    40561 aaatgttcca ccattagcag ttggggagat cgagcactta attactttag gtattcctgt
    40621 cgttcttgtt tcccgttgtt tcaatggtat ggcagaacct gtctatgctt atgaaggtgg
    40681 tggtgcgatg ctacaagaag caggtgttat gtttgtaaaa gaattgaatg ctccaaaagc
    40741 ccgtctaaag ttattaattg ctctcaacgc cggacttact ggtcaagagc taaaagatta
    40801 tattgaagga taatctagct tcctgtagaa atgtcccact aaaacatatt agtgggacat
    40861 ttctagtact ttaagcttta aattaggaca tctcctaaat gtctataata aacaactatg
    40921 tttcaaacta tgagattgtg cactcataat catttctata acagtttgag accagtattc
    40981 caataaatcc aactcttagc aatcagatac cgggtaaaca agtctttatt ttgtctcatt
    41041 aagtataagc ttacttgaat aataccaaaa ctacttgctc atcctttttt agtaatgatg
    41101 aagacgacct ttttctaaga acttctttgt cttttaaaat aaacaaagca catattaccc
    41161 tttattttag ttctcgtttg gaaaaaagaa agacattgcc taaaagataa caaagagtta
    41221 aaccaaaggc cactaatatg ctagtactag aaagatgttt atcaccaaga gacaaggata
    41281 ggtgtttaaa catcaaaact gggctaatat ctaacttaaa aaaatggttt gctaaagtag
    41341 cagatacttt atcaaaaaga aggacataaa gtatataagc tgtgattgac tgataagttt
    41401 tacgaagtat attaaacaaa aattgacaca aagcaataat agcaatataa aaaggcagtt
    41461 gtttaatcat ccgatctatg actattccat agtatgcttg accagtaaat aaatgaaatg
    41521 ctaaagcact aagaagataa gttaaactaa taaataaaag agataagcca aaactaacta
    41581 gcagtttata gattataatt aaagtacgat tttgttgttt gaccacaaca ttattaatcg
    41641 tacggtagtt atagtcatca ctaaaaaaga tacgggctgg tgttaaaaag aaaagcgtca
    41701 caaaatcagt aataatatta atgatttgta tcatgatgac ttggttaggt gtcttgcgaa
    41761 aactataggc tacaccaaca gcaatgacaa caagtagcat acaagaaaat agagctaaac
    41821 gctcttggcg tatccgaaat aaatctgctt taagatagga aatcataaaa acctctttct
    41881 aaattaatgg tgacgctgca tctttaccta acaaatcgag gtaataatgt tcaaagctca
    41941 cttgatgatg ataaatgtca aaaatctcaa caggcagatc tagaacaatt ttgataagct
    42001 ccattactga taaagttggt tttattagta gcatctgacc atcagtctca actctaagcc
    42061 ccaattctaa aagtctattt tttaccagct gatcatcgct tgtatgaagg gcaatttgta
    42121 cttttacttg agctttaagc tctgctttgt ccatactctt aataactttg cctttatgca
    42181 taatcacgta acgatcaaca actaagtcta attctgataa aatatgactg gaaatcaaaa
    42241 tcgtaatacc atagcaatct cttaggttca aaataatctg acgcatttct ttgattcctg
    42301 ctggatcaag accattaata ggttcatcta agattaaaaa ttctggaaaa tccagtatcg
    42361 aaagaccaat agccaaacgt tggcgcatcc ccaaagaata atctttcacc tttttctttt
    42421 tgctcacttt ttctagccca ataagttcca aaacctcata tatgcgctct tttgcatcag
    42481 ctaatctcaa ttgcaacgct gcatagtaaa gattatcatg agctgtcata ttgggataaa
    42541 gtgtcggtga ctcaataatt gatcccattc gatagggttg taactgtttg atttgccctg
    42601 aatcttttcc aattaggcca gataaaatac gcattaacgt tgtctttcca gcaccatttt
    42661 gacccacaag gccgcaaatt tctcctttgt aaatatcaaa agagatatca cttaaaacct
    42721 gatttttacc ataggattta tttacttgct caatacttag taacattgat tgctgtgtca
    42781 ttttccgctc cttttttgta cttatcgatt aatacaatat cttacacata ataacatctg
    42841 taaacggttg tgacaagttc ttctttttat taaaaaaata taaataagaa ttttaataat
    42901 atgattattt tagcaataaa aaagttatac tgaaaatggg ttaatactgc ttcacatagc
    42961 agtctcatcg taaagcataa gtaaaaaagg ccagaaatag tgacctcttt atactttata
    43021 acagtttatc tcaaaactaa ctaaatattt gtaaaacaac gacttgtttt aagttaatca
    43081 taaacttctt tttttctaat attttgtgcc actaattgcc actgtttttc atatatccag
    43141 ttaggatcag aaacaatcgc tgcagaaact ttgcgtgctt cttctaaaat aggataatcc
    43201 tcaacgatat cagctacttg aaattctgga attccagact gacgagtacc aaagatttca
    43261 ccagaaccac gcatttttaa atccgactca gctaaaacga aaccatctgt cgtttctgtc
    43321 atgattgtca ttcgtttttt ccccgaatca gttttgggat tagccactaa aacagcgtat
    43381 gattgtttat atccacgacc aacacgccca cgaagttgat gtaactgact taatccaaaa
    43441 cgatcggcat ccataataat catgatcgtt gcatttggga catttacccc tacttcaata
    43501 actgttgtgg atactaaaat atgacttttt ttatccttga aatcttgcat tctggcatct
    43561 ttttcatcat ttttcatacg tccatgtaca agagcaacct tagcaattcc ttcaaaataa
    43621 gtagataatt cggcatgcaa tgctactgca ttctttaaat ctaaagcttc tgattcttca
    43681 atcaacggtg aaatgacata cacttgagca tctttttgca attcaccttt tacccattcc
    43741 aacacagtcc ctagctgctc gtgtttcacc cagcgtgtca taataggttt acgaccggca
    43801 ggtaattcat caataacaga aacatccatt tctccaaaag ctgtgattgc tagagttcgg
    43861 ggaattgggg tggctgtcat cattaaaaca tcaggatttt ctcccttttc acggaaaatt
    43921 ctacgctgtt taacaccaaa acgatgttgc tcgtctgtaa tgacaagccc cagtttatgg
    43981 tactgtaccg agtcttggat aagagcatga gttcctacaa tcatatccac tgagccattt
    44041 gcaatagctg ctaaaaccgt acgcttgaca gcggctttca tacccgaagt taatatagca
    44101 attgatagat ctggaaataa ctcttgcaga ctaatgtagt gttgttcagc taggatttcc
    44161 gttggaacca tcaaagccga ttgaaaacct gctgtataag ctgcatacat tgatagacca
    44221 gcaatgactg tctttcctga tcctacatct ccttgcaata aacgattcat atgagctccc
    44281 gatgacatat cagataatat gtcatctaaa gagcgctttt gagcatttgt tagaataaag
    44341 ggtaaagagg aaatctttgt ctccatagca tgtttactat aaagaatagg caaaccattt
    44401 gtttcagatt tattttcggc tttcaaaact tgaaggttca tttgaaagta aaataattct
    44461 tcaaatttaa tccgacggag cgcttgctta tactctgtga tatcttttgg gaaatgcata
    44521 gctaaacaag cctgactacg acccatcaat cggtattttt ccaataaagt agctggtaaa
    44581 ttttccttca attccaaatg cgcatcgatt tcaaaagctg acttaatagc tttaatcaaa
    44641 gtagactgtg aaattccctg agctacgcga taaacaggtt gcatgtcatc ttcaacttga
    44701 gctaaaacct tcatcccagt aatagccgat ttagtggcat cccatttacc aaaaacagct
    44761 acctcttgac caagttctat tttatcagct aaatagggtt gattaaaaaa actaacattt
    44821 aagacagctt ccccttgacg caatttgaaa cttaaacggt tacgtttaaa accataatat
    44881 tgtacattag ctggagtaac gactaagcct gtaatgactg ctttttcacc atccactaaa
    44941 tcaaaaacag attttgattt aaaatcttca tagcgaaacg gataataaag cagtaaatct
    45001 tctactgtat aaatatctaa tttctgaaat ttttctgctg attttggtcc aaatcccttt
    45061 aagttggaca taggagctgt taatatcatt atctttttcc cttcacaaaa actcttgtca
    45121 gattgaagac aaagtttgtc gtgatacttt ccttaggtgg tgcttacggc agcgacgttc
    45181 tttggaattc cctgccttta tttttgagcc tgaggtctca aaaatcccga gtggcgtcaa
    45241 tctcgtattg acgccactct tttaccacag caaaaagcat ctgttttggc tcactttata
    45301 tgtaaaaatc ggaaaccgaa tgtcaaatca gcagagctat gcatgctttt tgaacataaa
    45361 actggggttg tctacgttct gactcttgta tctattatac aagagttcct atttattttc
    45421 agataaaagc cttttagtac ttttaaacag ttctaggggc tcgttaaggt agcatttgat
    45481 aaatggtatc gcagacacta cttagaagtt cttcatcatg tgaaatgagg atgacaacct
    45541 tatgttgggt cttcagctgc atgagaagat tagctaaagc cttcatttgt aacaaatcaa
    45601 gtccgctact tggctcatca aaaattaaga tatctttatc agccaaaaga ctagcggcaa
    45661 tcatcactct ttgttgctca cctcctgaca aactagctgg atgacgttct aaaagagtcg
    45721 ttaaagataa ccgctctatt acttctgtcg tccgtggatg tcgttcatgg cccaagttga
    45781 cttcctttga aaccgattct gcaaatagtt gcaaagaaac ttcttgcaag acaatactag
    45841 tctttgataa acgttgcttg gcagataaag gtatgccttg aaacttaata gttgcttttt
    45901 tatcgtctaa gataccagct atataataaa ctaattgcga ttttccaagc ccgtttgatc
    45961 ctgtaatgcc agaaatactt cctgcagcaa aactaagctg ttcaatacat ctaagtattt
    46021 tgcttcccgc tctaactgtt agatgctcaa tacacaggct atcatctggg cgataatgtt
    46081 gactctcaat cttaccagct aacacaggtt ttaggtcaga caagtctaag cgacgtagtc
    46141 ccatatcttg ccgttgttca tctgtcaagg ctagcaaatc ttgtgttgtt aacttatctg
    46201 ttaatctacc atttttaaag tagaaaaagt tatctgccaa atccatcaag taatgtaaac
    46261 gatgctcggc tacaataatg gtttttcctg ctgcttttaa ttgggtaaga taggctttaa
    46321 cagcagctat gcctgcacta tctaagttag cagttggctc atcaaaaagc ataatattag
    46381 taccttgcat aatggccgtt gcaatagcaa ctctttgttt ttgccctcct gacaatccaa
    46441 acatatcctt gttaaggagc tctgcaaaag caaaatcttc tgctaaagtc caaagacgct
    46501 tcatgataac ctttgcatct agaccttgat tttcacaggg aaagaccagt tcgtgttgga
    46561 cttcgcgata gaaaaactga ctggctggat tttgaaaaac agaggccaca gatctagaaa
    46621 atgtttcaac actgtctctg cctgcttggc aatcagccac atctagtcta ccttcatatt
    46681 ttccagcata ataatcagga attatgccat taagaagttt taaaaaggta gatttacctg
    46741 aaccagaagg tccacacaaa acaatgaatt gtccagatgc aatttgacaa gtcggtacct
    46801 gacaagctgg atttttttga tcatgatagg taaaaacaag ttgttctgct gaaatcattg
    46861 aagtatcgtg atgattatga taacagtaat ccaaatctgc accccccaat ctttccatgt
    46921 taagtgtgag ctaaagcatt cactggtgcc tttgttgact gctagccctt tagttagact
    46981 agcgatagtt agttcttggc tacttcttat caaagataaa agcaatggaa ccattaaata
    47041 ctccaagtat tgtttaggtc tgatcaaaat agaccatttt gttaaaataa tccccctgat
    47101 tgttaaagag cgatgaataa cacaacattc ttgtctaatc attggtatga aacggcacat
    47161 aacggctaag gtcaatagcc agacttctgg gaaatgccat ttgcgtaatc catgaaccaa
    47221 ttcgtagatg gtagttgtct taatagtaat taaacctgct agtaaagaag ggaaaactaa
    47281 ccttcctgct attgagacaa aactcaataa gtgatcaaga taagaaggga aaatagatag
    47341 cgggattaca gatagaccga tcattaacag ataaacaacc gccaacttga acgctagctt
    47401 tttcttattt aaagcagaca aaagtaataa gagaaaaata acaattataa attctaaaaa
    47461 gccatcaaca cgaaaaaaga agcaggcatt ggcaagtacc aacaaaagca gtttggtgcg
    47521 aacatcaagc ctcatgataa caatcctgat ttgataaaat gtttctttag taaataatgt
    47581 gcaaaagctg accctaataa ggctcctgca agaacaattc ctacaaacca aataacatgc
    47641 cctaaactaa aatcatacat aatgcgattg acataggtca tacttttacc gcgggctaac
    47701 aaactttcaa cataggcatc tttcaacaac cacatcagca aaatagggcc actattgaca
    47761 aaagcaaaaa ccatataaga taggtcatta aaaaaccttg acttgtattt tcctaaagaa
    47821 gcaataatat ccgctattaa accgaaaata atgctgggaa acatcgcggc aaaaaagtga
    47881 ccactaagga agaaaaaacc tcccatcatc agtcctaata atgttattgg cccaaatgtt
    47941 tgcaatttag caatcaaaag aaaataaatt gttcccccca gtaaagctgc aaaggcaggg
    48001 gcatataaca tatttcctga gcgatcaaaa aagatgttaa taaacgtgcc tagaccaaca
    48061 caaataaagt agagcgcggc aaatgcgcct gttatcataa tatcttttat tgttaactgt
    48121 ttcatttttt attcacctct tttaggaaac cattttttac gcaaaataga tgatcagcac
    48181 aagctagggt tgatggcctg tgagaaatta agaagaccaa tccttgacaa tgtgttttaa
    48241 ttaaatcaag caagatagct tcatttagag aatctaaatt tgacgtgggt tcatcaaaaa
    48301 tatagcaact cgcatctttc aataaagctc gcatcaactc taaacgttga ccttctccag
    48361 ctgaaaagtc agaaggactc ttgataatcg tatccaaacc ttccttacaa gctaacagtc
    48421 tgtctttcat accacaagcc tcagctaaat tccaaatgga ctcatctgaa atatcttgac
    48481 ggccaaaggt aagattttca cggatagact gttggaaaag ctgcgctgtt tgtggcacat
    48541 aagcaatagt atcttgtaat ttagcagcat ttagtaagca actattccta tcattaagaa
    48601 aaatatctcc tgtcttccaa ttataccatt tcataattaa tttcaccaaa gttgatttac
    48661 cagatcctga ttcgccttta atgccaataa tccccttttc ttgaaaggta actgataaat
    48721 ccttaaaaac cagctcttgg cgctttggat aagcaaaact gaggtcctca aaagaaacac
    48781 tccttaaacg atctatttgt tttgtgcctt catctactat gacattttcg tctagaaggt
    48841 caaaaatatt tcgagccgca ttcatagcac gcttaaaacc caatggcaaa cgtcctagtt
    48901 ctaaaaaagg agaaaacgaa gcagtgaaag caataaaagt taataagcct ttatcaaatg
    48961 ataagctgtc atggcatatc ccatcaaaaa ccatataaga aaatgctaag atcattaagc
    49021 caagccagaa aaaagtcaat gccatttgca aaaattgggc ttgcgctacg ttacgatcaa
    49081 gagcatttac atgattactt ttttttatta atcgttcaaa ttgctcgtct aatacctgaa
    49141 attgcaaaag atctttgact gatcgtaaac tctctaaaaa ataagacagg taatcttttc
    49201 gaccttcatt ttggcttttt agtaaaacct gtaaaatatt agcaaaataa atgggtataa
    49261 caatggctaa acaagcatag gttgccaaag ctaataaggc taactgccaa ctactttgac
    49321 aaaagtacca gaacattaaa cctgcagaca atattgctgt acaaataggc gcgattgtgt
    49381 gggcaaaaaa aacttctaat gcctcaatat cttctccaat cattttaagc aaataaccac
    49441 tgtcttgact atccaagcaa gctggagaaa gagctcttag tttcttaaag atcaagttcc
    49501 taaaagctgc taaactatga aaagcaacaa aatgaccaaa ataatgctct ccataacgaa
    49561 caaaacctct taaaaaggct agagcaatca aaagatataa agctaatatt ggaatcactt
    49621 cttgtctaat agctagtagt cctaaataag ctattccagt tggaatactt accgtgatga
    49681 caaaacccat aacagcaaag ccaacagcca agataatcca aggtagcaga gttttcatta
    49741 gggttaataa acgccaaacc aggcttaagg tagatctgtt aggtttagcc ataaatactt
    49801 gcctccagtc ttgcttgagt atcaactagg tgacgataag ttggttggtc ccgataaagg
    49861 tcgcaaggtt tgcctaaaca agcaggctgc cctgtgctta aaaagagtac ttggttagct
    49921 cctttcagtc gagacatctt atgagtaatc acaataacta ttgccgtctt agctaatctc
    49981 gttattaaat tgtcaataat acgttcattt tctgcatcta gactagatgt tgcctcatca
    50041 aagatataaa gagacctctt acttaataga gctcttacgc aaatcacctg ttgcttttgg
    50101 cctggtgata acagcttacc attttcacca actattgtgt caaggccatc tggtagccag
    50161 ttgatgaagc ttaacaaacc atgttgatct atccaatcta agatttcttt tttagagaga
    50221 tttgcggcta accttaaatt atcgtaaatg ctacggttca ataaggtaga ttggtccgat
    50281 acataaagaa cctgctggtt gataatttct tgcgacaaat tgtcactgtc taaaccgtca
    50341 aataaaatat gcccagtcgt tgcagactgg cgtttcaaga ggagttgagc tagacttgtt
    50401 tttccttgtc ctgacacccc cgcgatagct gttagttggc ccttcgttaa tgtcatggta
    50461 accccactaa gcactgtttt tttctcataa gctaaagaaa tattttggat gtcaatctgg
    50521 ttaaagttta ttgctgtttt actcttgtta tctttccttg ctggaacact atccaagaaa
    50581 ctaaagatac ggtcagccat tttggtattc atcatgacca agtgcatgcc ataaccctgc
    50641 tcacgaatcg gtgtaaaaaa ttctgtagca atcaagagaa aaaagaggaa attaaaaaaa
    50701 gataactgac ctgttgccaa agcttgaacg gctaaaaaac ctgacaaacc aattcccaga
    50761 tacataactg catccatata accaactgct tgtaactgaa agccaagcaa agacatggta
    50821 gcctttcgaa actgttctgc cttacccgaa aattcttgct cgtaacgttc tgttgcttga
    50881 taagaataca gtgtattaag accttttaag tcatccataa ataaattacc aacatccata
    50941 taagaagacc aataatgact cataatttgc ttagaccgct tttgcatagc aacgattgaa
    51001 agtggaatca gaggcagaac tcctaaaaag acaaggcctg ccaatggata aattaaaaag
    51061 actagtatca taatagttgt gcagttccac ttggttctca tagacaaaga caaatagtaa
    51121 ccataataag tatccaaact atcaatcccc tgtgaagcca acgttaaaat atcagcatca
    51181 ctggcatgag catcaaattg cccgtctaaa tcaataaaag cctcaaagaa agattgtttg
    51241 agtgaatctc tagcaaattg tgaagcgatc ccttgcagtt gcttgcctaa tatagcaaga
    51301 acaaagccta ccacatttaa aagtaggagt aaacctgcca agcgtcctaa ggcaatagca
    51361 tgacccaaaa taaaggtcga aaacgttttg gcaatgaggt aaaaactgat catcctcatc
    51421 acaaattgta accaagataa aaaggctgac acataaagca aatacctttt tggtgcaatt
    51481 cgttcacgta atcgttttaa cagtcttttc ctttttcccc ttgatattgt atcttctgtt
    51541 tccatcatct gttcttgttc ctatctctcc tttgagttct aatatcattg gtttcattga
    51601 ccaatgaagt gaggacaaac tgttgaccat ttctctcaac aaagggcaat tcaacaccaa
    51661 agacatctct gataaactgt tgatcaagga ggtctcttgg ttgcccttgg gcataaagtc
    51721 gcccatcttt cagtccaata agatggtctg aaagagacaa ggcctgattg atgtcatgta
    51781 atactaacac aatcgttaag cctagctctt ggttgatttt agtaatcagc ttgagaatgt
    51841 caagctggta cttaatatcc aaataagtcg ttggctcatc taaaaaaata atatctgtat
    51901 cctgggcaag ggccatagca atccaaaccc tctgctgttc accaccagaa aggtgttgga
    51961 tgtcacgata aacataatca ctcaaagccg ttacttctaa ggcccaagca aggcgttcct
    52021 catcttcttt ggtagtagtt ttaaaaaaag aacgacgggc aagcctagcc atggctacca
    52081 attcacccac taacaaacct tcgaccactt gatggtattg gtgtaccact gccacttttt
    52141 tcgcaaaagc cttgagagaa atcgttgcta attcttcctg ctcaagccaa acctgccctt
    52201 gttttaacgg aaggtttttg gttaataatt gtaataaggt tgacttgcca ctgccatttg
    52261 cccccataat agtggtaatt ttcccttttg gaatgctaaa ggtcaggtca tctaaaacaa
    52321 gtttttcctc ataagcaaag gaaaggtttt gcacctgaat atgactgctg ttcttactca
    52381 tataatatca gacctcctta gcaggtaaat aaagtaaggc ccgcctacaa tactcattat
    52441 aatcgcaggg ctaatttcca atgggtaagc aagacttctt cctaaagtat cggctagcaa
    52501 aaagacaaag gctccaagca aagctgaaaa aggaattaag atttggtgct tacttccaac
    52561 cagcaagcgg ctcatatgag ggacaatcaa gcctaggaaa gaaaccactc caacgatcga
    52621 agtggctacc gaagccaata aaacagcaac caaggaaatt cccaaccgta acgctgtagc
    52681 atcgattcct aaatgacgaa tcacctgatc atctaaaaga agaaggttac aggtttttga
    52741 caataacaaa gctagtaaca agccaatgaa tgtataaggg aataaaaccc ctacatcagc
    52801 ccatgttttt tgactaatat gacctgctaa aagagcattg accatgggac tagctgaggt
    52861 gaaaaaactg gttaaagcag ttgataaccc cataaataaa gcattaatag caatccctgt
    52921 tagaataagc cgaataggat taagcccttt cttccatgct aaaccataaa tcagcaggaa
    52981 agacactccg cctcctaaaa aggatacgat tggaccatac agcagcaact gcggtagaag
    53041 taaactagag actaaaacca taaaactagc accactacaa atccctgtaa tagcagggtc
    53101 tgaaatagga tttttcaaca ctgcttgaaa aagaactccc gaaacagcta tccctgctcc
    53161 tgctaataaa gcaatgacaa tccttggaaa acgcaaatca taaatcaaag ccacttgggg
    53221 gtcataagtc acaaacagtc ccttgacaat tgccccataa gaaaccgcca aaccaccaag
    53281 ggataaggca ataaccgcca aaaataggag gctgagaatt aaaagaacta gataaagacc
    53341 acttctgaaa cgttttttag ccagtaggga ttgatccctt tgtaaatctg atgctgtcat
    53401 gttacggatg atctcccacg tggtcaaaaa gctgtgttaa ggtgtccaag gcttctgggt
    53461 agttcaattt agcactcatg ccaaacaggg tattgtccaa atcatagact ttcccttcct
    53521 tgactgccgt aaaatgtttc caaatatcat tttcagcaaa ttctttgtca aacatcactt
    53581 ttaccttgtc tggaatggcg tgagctgttc gtaaaatcaa gtcaggctcc ttagccagca
    53641 tgtcttcagg attaactgat agaaattctt tctcatctga ctgataaaca ttctcaccac
    53701 ctgccaaatc caaaagattc cctacataag attggttcgt cgccaccaaa taactacctg
    53761 gcaagcccat aagaataagc actttaggct ttttcttccc cttacgttta gcttggaaag
    53821 cacgataata gtcctggtat tgctggcgca attcttttgc ttcttgttga cgttggaaaa
    53881 ggttccctaa atcatcaatg gactggtaca tgccctcaac acttcgtaag ttcaaaaaac
    53941 catactcagt atccaatttt tgatacttgg gttccaaatc ttcttgtaaa gaattgggac
    54001 tcaaaatcca agttggtttc aaagaagcaa tcaactctat atcaggattc atgggtaaac
    54061 ccacacgctt aacagcatca tagcgtttag gaagggtata taatttacta tcacaaaccc
    54121 caacgaggtc taaatttaaa cggtcacaga tatcaaccac agcaaccgaa gtggctacaa
    54181 ttctctgctg ttcagtctct ttagccgttt tagggtgctg attcacacaa gctaccaaaa
    54241 agaaggccat taaggctaga ccaattcctt tacatcgttt tatcattttt tttccctctt
    54301 tttccaaacc catacagcaa accctcctaa catcagaaaa aaagttggaa agtagtaaat
    54361 catgattgat aagtcttttt tagaccgaaa cttatcttct ttttttaact ctaaagaagt
    54421 cgttaagccc atcttagaag gaagaatttt tttatctgat agactcttgt tatttgatga
    54481 gttggcttta ggcttattct gagttatcat agcacctgtg tgagactcat cttgactttc
    54541 tcctagtttt gtatcaacag gcttttgact gtcttttact tcttgatttt gagaattgtc
    54601 tgtttcagta acaagctggg ccaacatatt acctgaatac ttttgtatta actctgaagc
    54661 tgacaggtaa aagaccactt ctctgcccat aggttcaaca aacatgcttc ctcgaatgat
    54721 actatttaca gtaggcaaac taatagcaat atctagtgtt gtcccattgg tatcagtacc
    54781 tttttgggtg atattgtaat caactgcctg aaagcttcca gttcctccag gttgtatcca
    54841 gaactgataa ttgcccgaat aatcagctaa gctcatacga aaagtaagaa cgatctttcc
    54901 agcatcagat acttctagca tggcatcact atagacagtc ccttcaacca taccttgacc
    54961 aatatcaaag gaatgctccc ctccgctatc ttctatctgc ccagatatcg gatgacgata
    55021 atttctctga ataatacatc cataaatttg acctttatct gcatacacaa cacctgtcat
    55081 tgtcgataaa cttatcatga acactactat tacctgcaac aattgcttta ttactacctt
    55141 tgtcatatgc tcctcttgtc tatcttttct taaacatctt atttcatttt ttaaatgaat
    55201 cccattttat aacatctcca aatgtgaaaa acacacctat cttgcgacta cttcaacctg
    55261 tatcaggagt cctgtcggaa ataggtatgt ttttagctct tgctgactag cttttttgtt
    55321 atttcacttg gtactaagtt tcttatttaa ataatgtctt tcgaccaata atgaatccca
    55381 gagctacgat cataaagcta gatagacctg caattaagtg ataacgagag ctactttctt
    55441 caccatttga ttgttgattg gaacgatgtt tcttatcaga ttttttagtc ttagtatctt
    55501 ttgccgtttt accttcaatt gatgtttgat gatcacgcac taactgcttc aatttctctg
    55561 ccttatcagt atcatctgtc ttagaagttt cttgagttga ttggccggtt gcttttttag
    55621 ccaggagatc agttaagtta gcaataccag tagctgctga aggaggactt gtaggtgttt
    55681 tttcttgttg acgattttga ggtcctttca actgatctgt tgaagttaga tggctatttt
    55741 cttgtggatt attagtttct ttgacaacct ttgccttctc tgttgtaagg cttgcccagt
    55801 ctaaacgcat aaaaacggtt tgaaggccag acccttttga aatggcatcc atgataggca
    55861 caaagacctg taatggcaca agtccgtctt tcttcgcttg ttcaatcaat ttcatacgca
    55921 gcacttttgg atagtttttt ccataacgat ctgccaatgg taggccagtt acatccgtga
    55981 aataagacac aacctctgcc ttttttgttc gaccaactgg tttaccagct aaatctcttt
    56041 ggtaaccatc tacgaaatag ctcaattcac caaggtagcc taacatttta ccaaccttta
    56101 tacctctaaa ctcaacttct aaataggaaa cacctttttt aactaccaaa gtcactcgat
    56161 gattaatagc cttgtttgac atggactcag atgctaagtc agtttttaac atgctggcat
    56221 ttaaatagta aataccatca cgcaattgtt tttgatttaa tgctctaagg ccgttctcaa
    56281 ctaaatcttt ctgatgtgaa tgtggtcctt tcgccacaag gatatcatta gatgtcaaat
    56341 agatatgttc tttttgagta gcaaatttct ttgttattaa agctttgcga atccgatatg
    56401 tacctggatc ttttaaagaa aactctcccg ttaagtcatc tttcggatca tttgagagaa
    56461 gcttttcgtc aaccgtcaca tactgtccat tggaagcttt tttttgcaac tgaatcacaa
    56521 tactccaatc gacttgcata tcattaagta aagaaacagt atctgaacct ttttcttgta
    56581 acaattgttg atattcttca atagacacta gttctttatc aatggcagaa tttgtttttt
    56641 gctcccaata atacaaatct aaaagactga aagcttgatg atattttatt ttttcgccat
    56701 ctaaagaagc ttcaagtttt gcaatatgtt tttgtggagt cagtttgtgt tgtccgataa
    56761 gagctcttac ttttggactc acacttttta tctgattgaa cttcacatct aaattaagcg
    56821 tttcaacatc tggaaatact gattcttcaa cctgagtaag caagttattg aaaaaatcaa
    56881 gttttgttaa ttggttattc tgtttaaata taccatttgg aagatttgaa atttcattag
    56941 ttgataaatc gagtacagat aatttaggaa gatttttaaa tgaaatatta tcaatacgag
    57001 taatatgatt tctacttgcc acaatagtgc ttaaggcgcg caatttttct attgtttttg
    57061 gcagtagtgc taaattattt tgagataagt cgataaaatt aagtgatgtt agaggctcta
    57121 gcgctttttc aggtatctcc tcaagactat tttctgcgaa acctaatgaa gtcagacgag
    57181 acaatccttc aaatgggtta tcacaaagtc ggccaatacg attcttggaa agatcaagtt
    57241 gctccaggtg atgaagcgac tggaatagtc ctccttcaag agagtgaata aagttacttg
    57301 ataagtagag ttctcttaat tgagcattgc ttttaaatgt atctttgtct agataagtta
    57361 aatgattact tcttaagtta agaaatcgaa gttgcttcat ttgactaaat aactcttttg
    57421 gaatttccgt aatttggttt ccatccagat gtagttctgt aatattttta gcatgtttca
    57481 ataaagaaat atctgttaac tcgtaatggt ctagacgcaa ctcacctcga atctgttcta
    57541 attccgtttt tgataattta ccatcgccgt ctaaatcttt gccaagttta actaaaactt
    57601 tttcaagacg ttcagtccca accccttttt ctttatcatc agtttctacc tgataaccac
    57661 tccaaccttt ggtaacggtc ttactaaagg tcatgtcaag tttggtgtat ttgtcatagt
    57721 ggtttaaatc actttcttga cctcccatgg ctgataccaa aacagcacct ttgtgtaatt
    57781 tatccaaatc atcaataggc atggtaaatt cgcttcgaat atagctacca ttgatatctt
    57841 tttggccaac ttgtttacgc actgctgctg ggtaggtccc tttgctttca atagaaaagt
    57901 caatcaaaaa ttgtcccaaa gcagtattaa gcatggaaat ttccattgta ccatctgctt
    57961 taaccactaa tttggctctt ttatcaaaag caccttgaag catggaggac tcttctgagt
    58021 tttctttatt agctttaaag tttagcgtat aggttccttc tgtgagattg ttaatagaaa
    58081 cctcacctgc ttgataagac tcgatggtat cttttaacag tcgatgagta tcggcgagta
    58141 gcttactatc tttgatttct ttgtaagaat ccttgatgac ttgaagtttc tcagccagat
    58201 ctttgaccgc gtctttgttg ctttctttag caataatcgc atccgcttct ttgatagctt
    58261 tttccaaagt ggtgacatcc aactttgttg attgtctgtc ttcagcagtc acatgttgtt
    58321 tttgtttggc agatacaaaa tggatttgac catctttctt ggtaacggta atgataacgt
    58381 cttcaaatcc ttttgaggat atcacgattg tattttctcc atctttgaaa gcttttgttc
    58441 caagatgaag ccctgtcata ttcgagaccc agccattagt atcttttaca gaatctgaaa
    58501 taagatcttt ataaactgta ccattgactg taacctttgt gatttgctga gtcaatgctt
    58561 ttatctgttt gttatcagaa taacgatcaa tttctggaaa taaaattgca ccatcttctt
    58621 gactcaattt tgttattaat gacaagttag tagtattttt cccagattta acaacttttt
    58681 gtgtgccttg gttttgtggc actgttttat cactgagcac atcttttttt aatgaaccct
    58741 gatgatctgt tgttcctaat ttttgagctg aaataaaggt cactttatcg ccctttttaa
    58801 taaaggtaat taggatatca ccatcttttt tattaacaat agtcaattca tgcttaccgt
    58861 ctttaataag gttagcattg atcttaatcc cttggtagtt aatatcaaag gttcgctcgc
    58921 cttccaggct tttttcatag acatcattat caacaataac cttttcaata tgtttataat
    58981 actcttttcc agctgattga ctagcgtaag ggcctatctc ttcaactaaa agtcgattat
    59041 cctgagttaa agctactgtt gtcacgagtt gtgactgaac taaagcctct tgtgatttta
    59101 cagtttgagt agcctgaatg agaacaaggg cagatattgc cacaaacgca catttgctga
    59161 tttttttcat tttcaatcaa ctttctaaaa atttttatga ataagctaac ttttttatta
    59221 actgaactta atctatcact ttgtgattat tttgtcaaga ttgtttccaa tggtccaatt
    59281 gtctgttaaa tagctccact atgtgagcta agacactagt aataagcctg gattgataat
    59341 gaggatatct ctgataaaag aattcctcta caacaatatt actgagataa agctagcctt
    59401 aggatagtta ttactagggc tgattcaatc attacttcat tcacaaaaca tgtaacacgt
    59461 tataagctcc ataattgtgt taggagacaa catgggatgt cactactgca tattcatcac
    59521 aataaaaaaa gacaatagcc ctaatcgtgc tattgtctca aaatcattta tttacttgaa
    59581 actttatcgt gttacaccaa cagtttaaaa ggcctaactc ccgctaagaa aattaagccg
    59641 taagaaaagt cattagttat tagtttttac tcttgccaat aacatatgtt agctgttcag
    59701 cctgctgagc tgtaaaggta cgataagaaa tcttacctaa gccgatacag ttagactctg
    59761 aaataagaat agacccatct tttctaacat cttctacaat tgatacgtgg ccataagtgc
    59821 catcagcgcc cgcttgccct ggtgcaaatg aaatagcata acctactttt ggagtctttg
    59881 aaagggcata ccctacttta tacttccaat ctccaccatt tcccataaaa ggatcaaatc
    59941 ggtaacccaa ttctttggcg cgattataca cataccaagt gcattgtccc caagcataac
    60001 tcgaagcttg ataatccaag acatcataac tcttagagag cttataacct gctggcacag
    60061 atgcaaaact agctgatgac tgcactttca attcggctgg aatggctggt gtgccaccat
    60121 ggtcatcaat ccacttatcc aggtcttcca taatttgtgc gcgacgttta ccactaccag
    60181 tagtatcagt aaaataaaca cccccgtcac ttgcaaagtt taattgacct cgtgaaaact
    60241 tagccgcttt taaatcttga agtgcaaaat tgctattttt gtttttaata atggtatctt
    60301 gtgtcatttt gacaatagca ctatcatcat taaacttact tgcttgagtc ggatctagat
    60361 caaaagctgc atagccaaac atattagctc caagcaaagt cgcaatccct tgagttccta
    60421 aagaactctc agacatcgca atagctacga tagctcgaac atccagccca cttttctttt
    60481 cccattgcaa tagcttctca ccattaatac gtgtgctgtc ataggcaatg cctgttgatt
    60541 ttaagtaact atcaatctgg tcagctttaa taccataacg gcgagataaa agatggtggg
    60601 tataggcatt tttaccactc caatgctcta catatgccgc gtatgtgttg acagaaggga
    60661 tatctatctc attcaaatct aaatctgata cgtaaggtga caacgactga ataggagttc
    60721 ttacctctgg caactgtctc gacaatgaag aagcaggtgc cgtatcaact ttagatggtg
    60781 atggtttggg ctgatcagtc ggttttggct ggtcagttgg tttcgaatga tcagttggtt
    60841 tcgaatggtc agttgattta tcatctacct ggttttctgc ttctgccttg ttgtccgaag
    60901 aacctacagc agactgacta gaatcgcttc tttttttatc atccgcgtta acaagactat
    60961 tagagtttgt ttctgcagaa gcatcaaggg gaccttggtc agttttatct gatgttgtag
    61021 gtgctgcatt tttattattt tcctcttttg aagaagaatc actggtttca tttgtagttg
    61081 ctttatgcgt ctcaagcatt acatcttgag ccaacactgt catgctttct gctgtcgggg
    61141 ctaagagact tagtagcatg gcaactctta atagtttgtt tttattcata tattaattag
    61201 tcacttcttt ctaatgtcct cactttatta taacattaaa gataagcaca atgcaattat
    61261 ttttacgtga ttttcttaat atatccgagg aatacggtca cttaaaaggc atagaacttc
    61321 ataattgatt gtattacggt aatttgcgat atctgttgta gaaatatttt tttgctgatt
    61381 gctgccaatc aaagtgactt ttgttcctaa aggatatgct ttggaaagtc gtatggtcag
    61441 ttgatccatc gatacacgcc ctataatttc acagaattgt ccatcaacta acaccgaaaa
    61501 gccttgcatg ttcctggtcc agccatctgc ataaccgatt gggacggtcc ctacatattc
    61561 agactttttg gcagtataag taactccata accgactgta tcaccagctg aaatcatctt
    61621 gacatgcact aagctagatt ctagagataa agcctcttgc agtggaaatg gtaagcttag
    61681 atcagaacca cttggattca aaccataact gacaattcct aaacgaacag cattaaaaat
    61741 ggtatcacta tgccagatac ttgtggctga attactagca tgtactaaac gaggcttatc
    61801 ctcaagtcca gctatcagct ttttaaaaaa ctgtaactgc tggttaaatt tagtatcatc
    61861 tgcctcatca gctgtagcaa aatgagtaaa aataccttct acatcagcac ccaactcttt
    61921 tagactatca atcaataaat tgacttcttt tgaagaacga agcccgatcc gccccatacc
    61981 agaatcaact tttacatgaa cttttaagcc ttgacattct tttttctcca gtctagctaa
    62041 agctatccag tctaaactag cgattgtaac agtaatagca ttagcaactg ctaactctaa
    62101 ttcatttggc agcaaaaccc caagaattaa aatctcttta tcaatacctg cttgacgtaa
    62161 ttgcaaagcc tcatcaagat ttgacacaca gtacccatcc acttgaggta ggagtgcttt
    62221 tgacacctgg acagcaccat gaccataagc atcagccttg acaactgcat acgtttttac
    62281 ccctagtgga atatgctttt gaacactggc aacattctcc ttaatagctt gtaagttgac
    62341 ccttgcaact gttgggcgat ggaaacttga aatcattttt tatcctccaa aataacacta
    62401 gcctgtacat aattgccact atgtgagatg ctaataaaac tatttccttt aaacggagat
    62461 tttgtcagaa tgggacatcc tctaacatca tttaaaatct caatatcttg aaaggttaac
    62521 cgcccaatac ctgtccctat agccttaaca aaagcttcct tacctgacca gcgtcctgcc
    62581 aaatagctga gtcgacgttt gtaaggaaaa ctctcaaaaa tagccaattc ctgctcagtt
    62641 aaaatttttt gagcaaagcg aggatttctt tgataaactt tttcaatagc tgaaatctct
    62701 tgtaagtcta ttccatgtcc aacaatcatt actttccacc aaaccttatt tcatcttaat
    62761 gttagaagat ttaaacagtg agaagctgag aattattctc agcttctttc tatataccta
    62821 actttgtcct gttgtgtctc gttcttatga gaaggattta cgaccgtgac aatttttgaa
    62881 ttttttgcct gaaccacatg gacaagcttc gttacgctcc actttgggta aatcatcggt
    62941 gttagctgac tgctgcgatt ggatgttttg aggtgctgct gttgtggcac gttgacttgc
    63001 acgttcacgt tcttgttcgt gaatttgtgc tttcatcatg gtacgtgtta catcaaactc
    63061 gatagcacca atcatatctt ggaacatctt gaaaccttct gcttggtatt ccaccacagg
    63121 gttattttga gcataccccc gaagtccaac agcattacga agttgatcta aggcatcaat
    63181 gtgttcagtc catttgttat ccacaatcat caaaatgagt actttttgga attcaataat
    63241 agcttcttga tcacgaagtt ttgatagttg ttggtcatag atagcaagcg ctctttgata
    63301 aagcttctct ttgatttgat catcttttaa accacgtaac tctttagcac taatagactc
    63361 ttctggtacc agcgaggtcc tagcaaaagt tacaatagca tctatagcat ctttacgatt
    63421 gctacgtgca tgagcatcta cagcacggtc gatagtacgc ttgatcatag ctttaatttc
    63481 tgggccaaga tctcgattag cagttatgac atcacgacgg ttagcataga taatttcacg
    63541 ctgttcacgc atcacatcat cgtattgtaa gacctgttta cgggtatcgt agttatttcc
    63601 ttcaacccgt ttttgagcag attccacttg acgccctaac atacctgatt taataacagt
    63661 gtcttcttca tctaatttca tccgatccaa aaaggctttt atacgatcag agccaaaacg
    63721 tctcatcaaa tcatcttcta atgaaagata gaattgggat tcacctggat ctccttgacg
    63781 acctgaacgt ccacgaagct ggttatcgat acgacggctt tcatgacgct ctgtaccaat
    63841 gacacataac ccaccaagtt cacgaacacc ttcaccaagc ttgatatcag taccacgacc
    63901 agccatgtta gttgcgattg taacagcacc acgttgccca gcattcataa tgatttgagc
    63961 ttctttaaag tgatttttag cattcaaaac ctcatgagga atccctgctt caaccagctt
    64021 gcgtgaaatc aaatcactag tttcaacagc aaccgtacct acaaggatag gttgtccttt
    64081 tgcatgacgc gttttaacgt cttccacaac tgctctaaac tttgattcta aggtcgggta
    64141 aagcaaatca gtgtgatcaa tacgggcaat tggacgattg gttggaattg gaataatacg
    64201 catgttataa acttcgcgaa attcttcttc ctcggtcttc gcagtaccag tcatacctgc
    64261 caattttttg tacatacgaa acatattttg gtaagtgatt gaggcgctgg tttttgattc
    64321 ttcctgaata cgaacgcctt cttttgcttc aatagcttgg tgcaagccgt ctgagaagcg
    64381 acgcccttcc atcgtacgac ctgtaaattg gtcaacaata agaatctcac catcttcgct
    64441 gaccacataa tcgatatcta acaacataat atagtttgca cgaagggcgt tgtctataaa
    64501 gtgagtcaag gctacatttt caatatcgta aagattgctc aagttaaagt aactctcagc
    64561 tttatcaata cctgaatcgc ttaatccaat cgttttagtg ggcacatcaa taacataatc
    64621 cactgacgtc agagttttta caaacatgtc agcacgaata tacaattgat tggtttcaga
    64681 gctaacagca ccagaaacaa ttaaaggtgt ccttgcctcg tcaattaaga ctgagtccac
    64741 ttcatcaacc aaggcaaaat tgagtgggcg ttgtaccatg tcttcctggc gaacaaccat
    64801 gttgtcacga aggtaatcaa aaccgacttc agagttggtt gaataagtaa tatcacaatt
    64861 ataagcttca cgtttttcag caggagactt agcagctagg ttgatcccaa ctgaaagacc
    64921 taaccagcta tacacttcac ccatttcggt agcgtcacgc gttgaaagat actcattaac
    64981 agtaataacg tgaacaccct caccagcaat agcattgaga taaactggca tggtggctgt
    65041 aagagttttt ccttcaccag tacgcatttc agggacatcc ccgttatgaa gaacaattcc
    65101 tcccataatt tgaacacgat aagggaacaa gcccaacaca cgttttgctg cttcacgaac
    65161 aactgcgaaa gcttcaggta atagttgttc gagggtctca cctttttgat agcgttcttt
    65221 aaattcaagt gtttttcctt gtagatctct atccgacaat gacgccattt ggtctgcgta
    65281 ggattctact ttttttgcaa ttttttctaa ttttcttagt tcgcctttgt cattttcgat
    65341 aactttgcgt agaatattgg ccattctctt tcctttcgat catctaatca tttcatttta
    65401 acataaatat gcaggcagtt caagaaaggt tggtaaagtt
//
LOCUS       DAUGUF010000006        63396 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUGUF010000006 DAUGUF010000000
VERSION     DAUGUF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63396
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.006"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            537..1064
                     /locus_tag="VIB71_000355"
     CDS             537..1064
                     /locus_tag="VIB71_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEQ8822115.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1064..2182
                     /gene="yqeH"
                     /locus_tag="VIB71_000356"
     CDS             1064..2182
                     /gene="yqeH"
                     /locus_tag="VIB71_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEQ8822116.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPDKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2207..2515
                     /gene="yhbY"
                     /locus_tag="VIB71_000357"
     CDS             2207..2515
                     /gene="yhbY"
                     /locus_tag="VIB71_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEQ8822117.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2584..3216
                     /locus_tag="VIB71_000358"
     CDS             2584..3216
                     /locus_tag="VIB71_000358"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEQ8822118.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3213..3806
                     /gene="yqeK"
                     /locus_tag="VIB71_000359"
     CDS             3213..3806
                     /gene="yqeK"
                     /locus_tag="VIB71_000359"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEQ8822119.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3830..4183
                     /gene="rsfS"
                     /locus_tag="VIB71_000360"
     CDS             3830..4183
                     /gene="rsfS"
                     /locus_tag="VIB71_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEQ8822120.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKETGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            4231..4974
                     /locus_tag="VIB71_000361"
     CDS             4231..4974
                     /locus_tag="VIB71_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8822121.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEVPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKLYADFEDKEPTETSKRWFFVAYK"
     gene            5196..6302
                     /locus_tag="VIB71_000362"
     CDS             5196..6302
                     /locus_tag="VIB71_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEQ8822122.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENVID
                     YQKLIKVYEKKSEQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6784..7500
                     /locus_tag="VIB71_000363"
     CDS             6784..7500
                     /locus_tag="VIB71_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8822123.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7703..8545
                     /locus_tag="VIB71_000364"
     CDS             7703..8545
                     /locus_tag="VIB71_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8822124.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYRVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8872..9717
                     /locus_tag="VIB71_000365"
     CDS             8872..9717
                     /locus_tag="VIB71_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8822125.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9972..11036
                     /locus_tag="VIB71_000366"
     CDS             9972..11036
                     /locus_tag="VIB71_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822126.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKVQLSANALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11037..11729
                     /locus_tag="VIB71_000367"
     CDS             11037..11729
                     /locus_tag="VIB71_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822127.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSVFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11783..13153)
                     /gene="brnQ"
                     /locus_tag="VIB71_000368"
     CDS             complement(11783..13153)
                     /gene="brnQ"
                     /locus_tag="VIB71_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEQ8822128.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFIDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
     gene            13387..14601
                     /gene="sstT"
                     /locus_tag="VIB71_000369"
     CDS             13387..14601
                     /gene="sstT"
                     /locus_tag="VIB71_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEQ8822129.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(14656..15330)
                     /locus_tag="VIB71_000370"
     CDS             complement(14656..15330)
                     /locus_tag="VIB71_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEQ8822130.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(15340..16731)
                     /locus_tag="VIB71_000371"
     CDS             complement(15340..16731)
                     /locus_tag="VIB71_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEQ8822131.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSIEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(16801..17514)
                     /gene="rsmG"
                     /locus_tag="VIB71_000372"
     CDS             complement(16801..17514)
                     /gene="rsmG"
                     /locus_tag="VIB71_000372"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEQ8822132.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQAFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            17664..18221
                     /locus_tag="VIB71_000373"
     CDS             17664..18221
                     /locus_tag="VIB71_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEQ8822133.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            18268..19164
                     /gene="htpX"
                     /locus_tag="VIB71_000374"
     CDS             18268..19164
                     /gene="htpX"
                     /locus_tag="VIB71_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEQ8822134.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            19398..19931
                     /locus_tag="VIB71_000375"
     CDS             19398..19931
                     /locus_tag="VIB71_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEQ8822135.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            20198..20884
                     /gene="covR"
                     /locus_tag="VIB71_000376"
                     /gene_synonym="csrR"
     CDS             20198..20884
                     /gene="covR"
                     /locus_tag="VIB71_000376"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEQ8822136.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            20890..22392
                     /gene="covS"
                     /locus_tag="VIB71_000377"
                     /gene_synonym="csrS"
     CDS             20890..22392
                     /gene="covS"
                     /locus_tag="VIB71_000377"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEQ8822137.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            22607..23101
                     /gene="nrdR"
                     /locus_tag="VIB71_000378"
     CDS             22607..23101
                     /gene="nrdR"
                     /locus_tag="VIB71_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEQ8822138.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            23085..24260
                     /locus_tag="VIB71_000379"
     CDS             23085..24260
                     /locus_tag="VIB71_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEQ8822139.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGDLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            24261..25163
                     /gene="dnaI"
                     /locus_tag="VIB71_000380"
     CDS             24261..25163
                     /gene="dnaI"
                     /locus_tag="VIB71_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEQ8822140.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            25226..26536
                     /gene="der"
                     /locus_tag="VIB71_000381"
     CDS             25226..26536
                     /gene="der"
                     /locus_tag="VIB71_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEQ8822141.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            26743..29841
                     /locus_tag="VIB71_000382"
     CDS             26743..29841
                     /locus_tag="VIB71_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8822142.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASNTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVYRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMKDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLPGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            30084..30686
                     /locus_tag="VIB71_000383"
     CDS             30084..30686
                     /locus_tag="VIB71_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822143.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            30726..32054
                     /locus_tag="VIB71_000384"
     CDS             30726..32054
                     /locus_tag="VIB71_000384"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEQ8822144.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            32100..32582
                     /locus_tag="VIB71_000385"
     CDS             32100..32582
                     /locus_tag="VIB71_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8822145.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            32694..34268
                     /gene="mltG"
                     /locus_tag="VIB71_000386"
     CDS             32694..34268
                     /gene="mltG"
                     /locus_tag="VIB71_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEQ8822146.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAAKRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASVLQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            34341..34823
                     /gene="greA"
                     /locus_tag="VIB71_000387"
     CDS             34341..34823
                     /gene="greA"
                     /locus_tag="VIB71_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEQ8822147.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(35447..36370)
                     /gene="yidC"
                     /locus_tag="VIB71_000388"
     CDS             complement(35447..36370)
                     /gene="yidC"
                     /locus_tag="VIB71_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ8822148.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMTFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKTPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(36452..36730)
                     /locus_tag="VIB71_000389"
     CDS             complement(36452..36730)
                     /locus_tag="VIB71_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEQ8822149.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGN"
     gene            36991..37728
                     /locus_tag="VIB71_000390"
     CDS             36991..37728
                     /locus_tag="VIB71_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEQ8822150.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFGEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYETPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            37767..38267
                     /locus_tag="VIB71_000391"
     CDS             37767..38267
                     /locus_tag="VIB71_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8822151.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLHRKT
                     LQSHNR"
     gene            38282..38971
                     /locus_tag="VIB71_000392"
     CDS             38282..38971
                     /locus_tag="VIB71_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEQ8822152.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            39149..39391
                     /locus_tag="VIB71_000393"
     CDS             39149..39391
                     /locus_tag="VIB71_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEQ8822153.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            39569..40363
                     /gene="racE"
                     /locus_tag="VIB71_000394"
     CDS             39569..40363
                     /gene="racE"
                     /locus_tag="VIB71_000394"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEQ8822154.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            40360..41346
                     /locus_tag="VIB71_000395"
     CDS             40360..41346
                     /locus_tag="VIB71_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEQ8822155.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQREIKVIPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDTILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            41325..41846
                     /locus_tag="VIB71_000396"
     CDS             41325..41846
                     /locus_tag="VIB71_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEQ8822156.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            41843..42304
                     /locus_tag="VIB71_000397"
     CDS             41843..42304
                     /locus_tag="VIB71_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8822157.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            42301..43047
                     /gene="xerD"
                     /locus_tag="VIB71_000398"
     CDS             42301..43047
                     /gene="xerD"
                     /locus_tag="VIB71_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEQ8822158.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPVTLEKYYKS"
     gene            43047..43751
                     /locus_tag="VIB71_000399"
     CDS             43047..43751
                     /locus_tag="VIB71_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEQ8822159.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKTNHTV
                     IERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQLSNFGAIILRKEKK"
     gene            43748..44299
                     /locus_tag="VIB71_000400"
     CDS             43748..44299
                     /locus_tag="VIB71_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEQ8822160.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAGLLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            44421..45143
                     /locus_tag="VIB71_000401"
     CDS             44421..45143
                     /locus_tag="VIB71_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8822161.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            45140..45403
                     /gene="yidD"
                     /locus_tag="VIB71_000402"
     CDS             45140..45403
                     /gene="yidD"
                     /locus_tag="VIB71_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEQ8822162.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            45581..46129
                     /locus_tag="VIB71_000403"
     CDS             45581..46129
                     /locus_tag="VIB71_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEQ8822163.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      46238..46362
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46441..47004
                     /locus_tag="VIB71_000404"
     CDS             46441..47004
                     /locus_tag="VIB71_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8822164.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            47006..47659
                     /locus_tag="VIB71_000405"
     CDS             47006..47659
                     /locus_tag="VIB71_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ8822165.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILVIGLSRIYLGVHYPSDILAGFVLGFGILQFIYPFYKQKRFEWRFLLKQD"
     gene            47952..48872
                     /locus_tag="VIB71_000406"
     CDS             47952..48872
                     /locus_tag="VIB71_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEQ8822166.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            48911..49465
                     /locus_tag="VIB71_000407"
     CDS             48911..49465
                     /locus_tag="VIB71_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8822167.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLLNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            49598..50932
                     /locus_tag="VIB71_000408"
     CDS             49598..50932
                     /locus_tag="VIB71_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEQ8822168.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            51010..51801
                     /gene="pflA"
                     /locus_tag="VIB71_000409"
     CDS             51010..51801
                     /gene="pflA"
                     /locus_tag="VIB71_000409"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEQ8822169.1"
                     /translation="MTEKDYEQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            51932..52867
                     /locus_tag="VIB71_000410"
     CDS             51932..52867
                     /locus_tag="VIB71_000410"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEQ8822170.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            52943..53596
                     /locus_tag="VIB71_000411"
     CDS             52943..53596
                     /locus_tag="VIB71_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEQ8822171.1"
                     /translation="MITIFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRSQLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(53641..54678)
                     /locus_tag="VIB71_000412"
     CDS             complement(53641..54678)
                     /locus_tag="VIB71_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8822172.1"
                     /translation="MLFMVNKKRRPLLKSHRHLLRLYTSLILLLVSLMGLALSLGESH
                     LSFLDLIHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAIVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTILSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(54639..55691)
                     /locus_tag="VIB71_000413"
     CDS             complement(54639..55691)
                     /locus_tag="VIB71_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ8822173.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLTNAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(55681..56613)
                     /locus_tag="VIB71_000414"
     CDS             complement(55681..56613)
                     /locus_tag="VIB71_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ8822174.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVTATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLESLREAILSSEN"
     gene            complement(56639..57421)
                     /locus_tag="VIB71_000415"
     CDS             complement(56639..57421)
                     /locus_tag="VIB71_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822175.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(57667..59112)
                     /locus_tag="VIB71_000416"
     CDS             complement(57667..59112)
                     /locus_tag="VIB71_000416"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEQ8822176.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            59200..60834
                     /locus_tag="VIB71_000417"
     CDS             59200..60834
                     /locus_tag="VIB71_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEQ8822177.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSVIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAISQIAEQLIRVIWMLLTTFLIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGVGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            61002..61631
                     /gene="upp"
                     /locus_tag="VIB71_000418"
     CDS             61002..61631
                     /gene="upp"
                     /locus_tag="VIB71_000418"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEQ8822178.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            61855..62445
                     /locus_tag="VIB71_000419"
     CDS             61855..62445
                     /locus_tag="VIB71_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEQ8822179.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            62940..63233
                     /locus_tag="VIB71_000420"
     CDS             62940..63233
                     /locus_tag="VIB71_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEQ8822180.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKGYQPPSY"
BASE COUNT        20369 a        10811 c        12957 g        19259 t
ORIGIN      
        1 ggtaaatcta tgaaaaaagt gtaatcattt tttgatttac agttattatc atgtgttatc
       61 tggcgactgt cctgtttaca agtaagttca caagtatggg ataaaatagt ataaactata
      121 gtaaatactg aatagtcaaa gaaaaatatc ggcataggtc agaagagctg atatgtttaa
      181 tactttttgc ggatatctac tgtatttaaa tgtatttgat atccttgtca aggatatacg
      241 tctaaacaag ttcaaaacga aatcatttgt gattatctta tcaggagttg actcttgata
      301 agatttttgt atatcagtac tgtggtacgt ttagatagct tggcagtgaa tttatagagt
      361 gtcaaacaac gagtgttttg tgttacacta accattagaa gagtctattg ttgagcatat
      421 caaggtgtta tcttttcgag ttgaggtatc atatctagta tatttaacta tggttttaaa
      481 tgctatttca aaaaaaatat gataaaatag aaagtactaa ttattttgga gatgacatga
      541 gtatcgatga ttataggccg acctatatgg tagaggctat ttatgattta agagcaaatg
      601 atttgttgcg tcatggtatt acggctgttc tagtggattt agataatacc ttaattgcat
      661 ggaataatcc tgatggcaca ccagaggttc gcgcttggct tgatgaaatg actatcgcgg
      721 atattagcgt ggttgttgtt tcaaataata aacattctcg tgttgagcgt gccgtttcac
      781 gctttggtgt tgactttatt agccgggctt tgaagccatt tgcttatggt attgaaaaag
      841 ccattgctcg ttatggattt gatcgcaacg aggttatcat ggttggagat cagctaatga
      901 ctgatatcag agctagtcat agagctggaa taaaatcagt tttagtcaaa ccacttgttg
      961 cttctgatgc ttggaatact aaaattaacc gctggcgtga acgccgtgtg atggcaaaat
     1021 tagaagagaa atatggtaaa ttatcatatc aaaaaggaat ttaatggaag aattattttg
     1081 tataggctgt ggtatccaga ttcaaactga agataaagaa aaagctggtt ttacgccagc
     1141 tgctgctttg aaaaagggta tggaaacagg agaactctat tgtcagcgct gctttagatt
     1201 gaggcattat aatgaaatta cagatgtcca tattaccgat gatgaatttt taagacttct
     1261 tcacgaagtg ggtgatagtg atgctcttgt ggttaatgtg attgatattt ttgactttaa
     1321 tggttctatt attccaggtc tatctcgctt tatttctggt aatgatgtct tactggttgg
     1381 gaataaaaaa gatattttgc caaagtctgt taaggatggt aaagttactc aatggttgac
     1441 ggaacgtgca cacgaagaag gtcttcgccc tttagacgtt atgttaacaa gcgctcaaaa
     1501 taaatatgcg atcaaagact tgattgagcg tatcaatgag ttacgtaatg gtcgagatgt
     1561 ttatgttgtg ggggtcacta atgttggtaa atcaaccttg attaatgcga ttatccaaga
     1621 gattactggt aacaaggatg tcatcacgac gtctcgtttt cctgggacaa ctcttgacaa
     1681 aattgaaatt cctttggatg atgggacgtt catttttgat acaccaggaa ttattcatag
     1741 gcaccagatg gctcattatt tatcccctaa agagctaaaa atagtgagtc ctaagaagga
     1801 aatcaagcct aagacgtatc aattaaaccc agaacaaact ctctttttag gtggtttgtc
     1861 tcgctttgac tttatcaatg gggagcgtca agggtttaca gctttttttg acaatcaact
     1921 agaattacat cgtacaaaat tagctggagc agatgctttt tatgataagc atgttggaac
     1981 tttgttaacc ccgccagata agaaagagtt gactgcattt cctaaattag ttcgtcatga
     2041 atttacaatt gatcagaaaa tggatattgt tttttctggt ctaggatgga ttcgtgttaa
     2101 tggtcaaaaa gactcaaaag cgatagttgc tgcatgggct cctgaagggg tcgctgtcat
     2161 tgttcgtaaa gcgattattt aaaaataaaa aagaagttgg aaaaaaatgc ttacaagtaa
     2221 acaaagagct ttcttaaaat ctgaggctca tagcttaaaa ccgattgtac aaattggcaa
     2281 aaatggatta aatgaccaca ttaagactag tattcgtcaa gctttggatg ctagagaatt
     2341 gataaaggtc actttgttgc aaaatactga tgaagatatt catgaagtag cagagatttt
     2401 agaagaagaa attgggtgtg atacggtttt gaaaattggt cgtatcttga ttctctataa
     2461 ggtttctgct aagaaagaaa accgcaagtt gtcccctaaa gttaaagcaa tctagtcctt
     2521 ttatttgtat agggactggt tttatgagac gaggactatt gtcgcgagaa ttttggagaa
     2581 agtatggcat tagaattgtt gacgcctttt acgaaggtgg aattagagga agaaaaaaaa
     2641 gaaagcaacc gcaaacagat tgggatttta ggagggaatt ttaatcctat tcacaatgca
     2701 caccttgtgg ttgcagatca agttcgccag caattaggat tagatcaggt gctattgatg
     2761 cctgaatgta aaccaccgca tgtggatgcc aaagagacta ttgatgagaa gcatcgtctt
     2821 cgcatgttgg aattggctat tgaagatgtt gaagggctag ctattgaaac ctgtgaactt
     2881 gaacgtcagg gaatcagcta tacctatgat acgatgcttt atttgactga gcagcatcct
     2941 gatgttgatt tttattttat catcggagct gatatggttg attatttgcc aaagtggcac
     3001 cgtattgatg aactggtcaa actcgttcaa tttgttggag ttcaacgtcc aaaatataaa
     3061 gctggaacct cttacccggt catttgggta gatcttcctt tgatggatat ttcttctagt
     3121 atgattaggg attttattaa aaaaggtcgt cagcccaatt atctcttacc taagcgggtt
     3181 ttagactaca ttactcaaga aggtttgtat caatgacata tgaagattat cttccttata
     3241 gcaggaccga actgttagca aaaattgcag agcagatgag ccctaaacgg tttaaacatg
     3301 tacttggcgt ggaaaaggca gccttgtcct tggcagagtg ttatggttgt aacccagaca
     3361 aagcagggtt agcagctctt ttacatgatt atgccaagga gtgccctgac caggtctttt
     3421 tagacttaat tgacaagtac caattatctc cagaattagc taaatggaat aataatgtct
     3481 ggcatggtat ggttggtatt tataagattc aagaagacct agggctaaaa gacaaagata
     3541 tcttgcgagc tattgaaatt cacaccgttg gcgctgctga gatgaccttg ctggataagg
     3601 tcttatacgt tgctgattat attgaagaag gtcgcatttt tcctttggtt gatgacgcta
     3661 gaaaaatcgc taagctcgat ttgaatcagg ctgttgccta tgaaacagtg aacactgtcg
     3721 cttatttagc ctcaaaagcg cagcctattt tcccacaaac tctggatacc tataatgcgt
     3781 tttgcagcta tttaaaggaa tactaatgga taatgatatg aggaataaaa tgaaaaaaga
     3841 agaactctta aaaattgttg tggaagcaac tgatgaaaag cgtgctaaag atattttagc
     3901 cttggattta gaggggttaa ctagtttgac cgattatttt gtgattgcga gtgcaacaaa
     3961 tagtcgtcaa ttagaggcta ttgcggataa tattcgtgaa aaggtaaaag agactggtgg
     4021 agatgctagc catgttgaag gtaatagcca agcaggctgg gtcttgcttg atttgaccga
     4081 tgtggtggta catctttttt tagaagacga gcgttaccac tataatcttg aaaaattgtg
     4141 gcatgaagcg cctgctgtgg ctctagatgc ctatttagct taatgttaca aagagacctt
     4201 gtcaatacga cagggttttt gaggatgata atggaacata attatgaaaa atttgcgtca
     4261 gtttatgatg ctgtgatgga tgattctcta tatgacttgt ggacagattt ttcacttcga
     4321 catttaccaa agtctaaggg tcgaaatcgt ttgttagagt tggcctgtgg aaccggtatt
     4381 cagtcagttc gttttgctca agcaggtttt gatgtgactg gtttagactt aagtcaagac
     4441 atgctggcta ttgctaaaaa gcgtgcgcaa tctgctaaaa agaaaattga ttttattcaa
     4501 ggtaacatgc tggatttgtc acaggtgggg cagtttgatt ttgtaacctg ctattcggat
     4561 tccatttgct atatgcaaga cgaagttgat gttggcgatg tttttaaaga agtttatgat
     4621 gttttagcaa acgatggtat ctttattttt gatgtgcatt caacctatca aacggatgag
     4681 tgtttccctg gttattccta tcatgagaat gcagatgatt ttgcaatggt ttgggatacc
     4741 tatgctgacg aggttcctca ctctgttgtt cacgaactca ctttctttat ccaagaagac
     4801 gatggacgtt tttctcgctt tgatgaagtg catgaggaac gaacgtatga gttattgact
     4861 tatgatattt tgttggaaca agcagggttc aagtcattta agctctatgc ggattttgag
     4921 gataaggagc cgactgagac tagcaagcgt tggttttttg tggcatataa atagaagaaa
     4981 aaagtagcct ttttagctat aggatttaat gaattatctt gaatgttact tatatgaaaa
     5041 gagttcatta ggcattaaat gctattatca aagcttagaa gtattggaga cattacgata
     5101 aagaaagcat tttctattat acgttgtgct taagcatttg atttaactct tattagccct
     5161 ataaaagatt atttagtaca atttgaggag attctatgac tgttaccgga attatagctg
     5221 agtttaatcc gtttcacaat ggacacaaat atttgctaga aacagcagag ggactaaaaa
     5281 tcattgctat gtcaggaaat tttatgcaaa gaggagagcc tgctcttatt gataaatgga
     5341 ttcgatcaga gatggctctt aaaaatggtg cggatattgt tgtggaattg ccctttttcg
     5401 tttcagttca atcagcagac tattttgctc aaggagctat tgatattctt tgtcaattag
     5461 gaattcagca attagcattt gggacagaga atgtgattga ttatcaaaaa ctgattaagg
     5521 tctatgagaa aaaatcagag caaatgactg cctatttatc gacgcttgaa gatacactta
     5581 gctatccaca aaaaacacaa aaaatgtggg aaatctttgc tggagttaaa ttttcagggc
     5641 aaacgccaaa tcatattttg gggttaagtt acgcaaaggc tagcgctgga aagcatatac
     5701 aactatgtcc tatcaagcgt caaggggctg cctaccattc gaaagacaaa aatcatctgc
     5761 tagcttctgc aagtgccatt agacagcacc tgaatgattg ggatttcata agtcattcag
     5821 taccaaatgc aggtttactt ataaacaatc cccatatgtc atgggaccat tatttttcat
     5881 tcttaaaata tcaaattctg aaccattctg atttaactag tatttttcag gtcaatgatg
     5941 aattggcaag tcgtattaaa aaagcgataa aagttagtca aaatattgac cacctagttg
     6001 acactgttgc taccaaacgc tatacaaaag ctcgtgtaag acgtatttta acctacattt
     6061 tggttaatgc taaggaacct actttaccta aaggaattca tattctaggg tttacctcaa
     6121 aaggacaagc acatttaaaa aaattaaaaa aaagcaggcc tctgattact agaattggag
     6181 cagaaacttg ggatgagatg acacaaaaag cagacagcat ctatcaactt gggcatcagg
     6241 atatcccaga acaaagtttt ggaagaatac ctattataat aaaaaatgag aggctcaatt
     6301 aaactctaat tgagtttttt tgggggcttg actctaatat tacgttgatg gtttatactt
     6361 cagttaatcc aatgaggaaa ttttataaca ataattaaaa aagtcagtca aaagatatgc
     6421 tttcgaagaa caggctaacg tttttacaag attatatcag taatcatttt gacaattgta
     6481 gtaatggaat gttgccaaaa tttagaatgt tgtgtgttat gaatgacaag attttaaagg
     6541 aatactaatt aaacgggagg tcgtgaaccg gaagctgttg tcactcaagc gccaaaatct
     6601 gtctgtaaca taatattgat gtatgggaac gcaattattt ggtttttatt gtgatgctta
     6661 aaacgatttt atatttctat tttaccaaag cttttcaaag tgctataata agggagttag
     6721 agtcaatatt agtaacgtta atgttgacaa tattcaataa aatactatta aaaggagaca
     6781 aaaatgggac gtaaatgggc aaatattgtt gctaaaaaaa ctgctaaaga tggagcaaca
     6841 tcaaaggtct atgccaaatt tggtgttgaa atttatgtgg ctgccaaaca aggcgagcca
     6901 gatccagagt taaatacagc tcttaaattt gtcattgatc gtgcaaagca agcacaagtg
     6961 ccaaagcatg ttattgataa agcgattgat aaagctaaag gaaacacaga tgaaactttc
     7021 gtagagggac gctatgaagg ttttggtcca aatggttcaa tgattattgt ggatactttg
     7081 acatcaaatg ttaaccgtac agcggcaaat gtacgtacgg cttacggtaa gaacggtggc
     7141 aatatgggag cttcaggatc tgtatcctac ttatttgata aaaaaggggt catcgttttt
     7201 gctggtgatg atgctgacag tgtctttgaa caattacttg aagcggatgt agacgtagat
     7261 gatgttgaag cagaagaggg aacaataaca gtttataccg ccccaacaga tcttcataaa
     7321 ggtatccaag cacttcgcga taatggtgta gaagaattcc aagttactga acttgaaatg
     7381 attcctcaat cagaagtagt attggaaggt gatgaccttg aaacttttga aaagcttatt
     7441 gatgcactcg aatcagatga tgatgttcaa aaagtgtatc ataatgtagc agatttttaa
     7501 attgacatag aataataaaa agagttgaaa actatttcag ctctttttaa gtgatgcttt
     7561 tataagtaag taccaagtaa catagtcgtt gttagaagat aatgaacaat agtaaatcag
     7621 tatcaacttg ataggaatca attattagtg aactctaatt aaaaatggta aactagacac
     7681 aagaacaaaa aggagagata ggatgattaa aaaacaatat ttaggaaggg caacaattgc
     7741 cctagcatca acccttgtac tagcagcttg tgggtcatca aaaacagctg agtcaggaaa
     7801 tcaggggagt tctaaagaag tcttatttgc aacggttgga acaacagctc ccttttctta
     7861 tgaaaaaggt ggtcaactaa ctggctacga tatcgaggtg gctaaagcag tctttaaagg
     7921 atcggatgat tacagggtgt cctttaaaaa aacagaatgg tcttctatct ttacaggttt
     7981 ggactcagga aaataccaaa tgggtggtaa caatatttcc tttaccaaag agcgttcagc
     8041 taagtacctt ttttcttatc caatcggatc aacaccttct gttttagttg ttccaaaaga
     8101 cagtgatatc aagagctttg atgatatcca agggcatacg acacaagttg ttcaagggac
     8161 tacaagtgtt gcacagttag aagactttaa taagaaacac agtgacaacc cggttactct
     8221 aaaattcacc aatgagaaca ttacccaaat gttaaccaat ttgagtgaag gcaaggcaga
     8281 tttcaagatt tttgacgctc caacggttaa cgccattatt aaaaatcaag ggttagataa
     8341 tctcaaaaca attgaactca cctcaacaga gcaaccattt atttatttta tctttagtca
     8401 agatcaagag aaattgcaaa gctttgttaa caagcgtatt aaagagttga ctgctgacgg
     8461 aactcttagc aagcttgcca aagagcacct tggcggtgat tacgtgccat cagataaaga
     8521 gttgaaactt cctacagcta actaaaccat ctattaacca gttattcatc tagaagactg
     8581 gtttttctga tcggaaacaa tattatagtt tatgaggtta tgttataaaa attgcaaata
     8641 gccttaatca aaatgagatg ttaaagtgct ttttgagaag tgaatattgt aagaagtatg
     8701 ctttgggttt tagtcctcaa ataccaagtt ttttgttgac taaacaaata aggatggtta
     8761 gcatagcata tagtttaaaa ctatgctata tgctagccat tatcaatttg aaaactatat
     8821 ctaattaaga tacaataatg atcgtaaaca aaatgaatcg aggataacgc tatgtctttt
     8881 aaaaaatgga ttggaatagt cggaatcgct ttagcatcaa ctgtattggt tgcttgttct
     8941 gaaaaacaag atgataaaaa cactctaact attggggtga tgacaaaaac agaatctgat
     9001 caagcgagat gggataaagt tgaagaatta ttgaaaaaag acaatatcac tttgaagtac
     9061 aaagaattta cagattactc gcaacctaat aaggcagttg ctaatggtga agtcgatatt
     9121 aatgccttcc aacactataa tttcttaaat aactggaata aggaaaataa ggaacatttg
     9181 gtggccattg ctgataccta tatcagccca attaaccttt tctctggaac cagtcaagat
     9241 gggaaggcta aatacaaatc agtagctgat ctgccaaatg gtgctcaaat tgcagtacca
     9301 aatgatgcga ccaatgaaag ccgtgccctc tatgtgctgc aatcagctgg cctcattaaa
     9361 ttgaatgtgt ctggtgatca attagcaacc attgccaata tctcagagaa caaaaagaaa
     9421 ttagatatca aggaattaga tgctagccaa acggcacgtg ctttagtatc tgctgatgca
     9481 gctgttgtca ataatagtta cgctgttcct gcaaaaattg actacaaaac ctctcttttc
     9541 aaagaaaaag cagatgacaa ttcaaaacaa tggattaaca ttattgcagg tcaaaaagat
     9601 tgggaaaaat cagagaaggc tgatgctatt aaaaaactca tcaaggccta ccaaactgat
     9661 gaggtgaaga aagtcgtgga aaaaacttca aatggtatag atgtatccgt atggtaaatt
     9721 ttagccattg ttataacaag agtgtggtcg tgtttaaaac acatgctttc ttttcttgca
     9781 tgcttgagga agagtttacg attaatttac ctttagaaag ctatttaaga ccttttccct
     9841 tttaggattt agaaaccttg ggaagactat tgcatgttat cttaatagtc atgattatgc
     9901 aggcgatgaa aacattgcta tcgtagatta ctgtcgccat atcgtactaa tagaggagtt
     9961 attaaaatct tatgaatgaa gcaataattc aattagatca tattgatatt accttccgtc
    10021 aaaaaaaacg ggttatcgaa gctgttaaag atgtcacggt tcatatcaat caaggagata
    10081 tttatggcat tgttgggtat tcaggtgccg ggaaatcaac tcttgtgcgt gtgattaacc
    10141 tgctacaggc accaacaaac gggaaaatca ctgttgatgg ggatgtgacc tttgaccagg
    10201 ggaaagttca gttatcagcc aatgcccttc gccaaaaacg acgtgatatt ggcatgatct
    10261 tccaacattt caatttgatg gcccaaaaaa cagccaaaga aaatgtagca tttgcgctcc
    10321 gtcattcgtc gttaagtaag actgagaaag aacacaaagt tatcgaactg ctagaacttg
    10381 taggtttatc agagcgagca gataactacc ctgcccagtt atcgggtggg caaaaacaaa
    10441 gggtggctat tgcgcgtgct ctagctaacg atccaaaaat tttgatttca gatgaggcca
    10501 catcagcact agatccaaaa accactaaac aaattttggc gctcttgcaa gaattaaacc
    10561 gcaaacttgg ccttaccatt gttatgatta ctcatgaaat gcaaattgtt aaggatattt
    10621 gtaatcgtgt tgctgttatg caaaatggtg ttttgattga agaaggttct gtccttgata
    10681 tcttttcaaa tccaaaagaa gccttgacac aggaatttat cacaacagct acagggattg
    10741 atgaggcttt agaaaaaatt aaccaacaag acattgttaa acatttgcct gcaaatgccc
    10801 ttctagctca gttgaaatat gcaggaactt ctacggatga gcctctactt aatagcattt
    10861 accgtcagtt tgaagtgaca gctaatattt tgtatggcaa tattgagatt ttagatcata
    10921 ttccagttgg tgacatgatt gttgtcttgg aagggcaagc tgaaaatatt cttgcggctg
    10981 agaaagcctt gcatgaagct ggtgttgatg ttagtatttt aaagagagga gcctagatgt
    11041 cacagttaat tcaaacttat ttgccaaatg tttatgaact cggatggtct ggagatgctg
    11101 gttggggctt agcgatttgg aatactttat acatgaccat tgtgcctttt attgttgggg
    11161 gtgctattgg tctcttatta ggcttgttat tagttttaac aggaccggac ggtgttattg
    11221 aaaacaaaac gatttgttgg gttattgata aagttacctc tgtttttaga gccattcctt
    11281 ttgttatttt gattgctatt ttagctagct ttacctattt gcttttaaga acaactttag
    11341 gagcaacagc ggccttggta cctttaacct ttgcgacttt tcctttttat gcccgtcagg
    11401 tccaagttgt tttttcagaa ttagacaagg gtgttattga agcagcacaa gcttcaggtg
    11461 ctactttctg ggatattgtc aaagtgtatc tcagtgaagg tttaccagat cttattcgtg
    11521 tttctacagt caccttaatt tctttagttg gggaaactgc catggcagga gctatcggtg
    11581 ctggaggatt aggaaatgta gcgatttctt atggttataa tcgttttaac aatgatgtga
    11641 cttgggtagc gactattatt attcttttaa ttatttttgc tatccaattt attggtgata
    11701 gcttgactag aaggtttagt cataaataaa cgaaacaaca ccctaagtaa aaacttaggg
    11761 tgttgttgtt tagatgatgt cattagcttt tcttcgtttt acttagtata agccctatta
    11821 aaaaaccaat agcagcaaat ataatccatc ccattgagaa ttgccctagt ggaacagttt
    11881 tttggaaaaa agttacaacg gcttctggta aatgaaataa tccagtcatt tgtgatagtg
    11941 ttaggagtgc atcaaatatg gcaggaataa aggttagacc aattgtagtt cgatagacaa
    12001 taggatcatt attgaagcat ttttgtgcca aaacaaggaa aattaaatcg actgttaatg
    12061 ggtataaaag gaataaaaca ggagctgacc agttgataat gactgataag ccaccaaaat
    12121 aaaagaaagc tgatagtaaa gtaaagatag ttgcccaagc aatatgagat aaagcaggca
    12181 ctaatttatg gaagtattca gcacttgacg tgattaagcc tgttgaagtg gttagacagg
    12241 ccaggaaaat cacaacagct agaaatgctt gtccgatgcc acctaggtaa aaacgagaag
    12301 catgacttaa gatttgaccg ccattaactg gattaccatg aagggtaaag ctgccatcaa
    12361 taaaaggaaa taatgattgt gatgttgctc caatacgacc gacaaagata tagacaagtg
    12421 ctaatagcaa aatggcaata gccccagaaa taagtgttat tttggtcact tctttgtccg
    12481 tcttagcgcc aaattgtttg gtagcctcaa tgactaaaat agcaaaaaca agagaagcta
    12541 gtgcatccat agtgccataa ccttgaatta atcctgctat aaaaggaaaa tctttaaagg
    12601 cattattaac accgacccca gcgttaaaag catcaccgta atttccagca ggatggacaa
    12661 aggacgcgat aaccaaaata gaaataacaa ctaacaacgt tggcgttaaa aattttccga
    12721 tattttcagc tagcttacta ggtttgatag caaggaagta ggacagacca aaaaatagta
    12781 tagcataaat agctttattg gttgtattat ctcctaagat aggagcgata ccgactgaaa
    12841 aagaagtggc tcctgttctt ggaatagcaa aaaatgggcc aatagataaa tacaaaatgg
    12901 aagaatagaa gattgcatac catttagaga tggggcgtgc caaactttca acatcgcctg
    12961 atccagattt agcaacagca atgacaccga gtaaaggcaa ggagacacca gttaaacaaa
    13021 aaccaatgat agaccataga atctgatgac ctgagtagat gcctaaaaaa gctgggtaaa
    13081 tgaggtttgc tgctccaaaa aatagcgcaa atagcatgaa tccaatgacg atatatacat
    13141 ttttttgttt catttataaa tagtctttct attgatacta atccgaagat tctaacaatt
    13201 ttaattatat tatgtgtcaa aataacaaca aaggttatta tatctaagat tacttcgata
    13261 gtcaatagaa attgactgaa aattcttagc acaaaaaatg gttaagatat gtagctcatt
    13321 cgatttgacg aatagataga attatattat tataaaaaac atgtaacttt agtaaggatg
    13381 taacgtatga aaaaaatata tgatttatgg gttagggtta gtctaatcaa aaaaataggt
    13441 atcggtgttg taataggagt catgttgggc attttggctc ctgatcttac aggttttagt
    13501 attttaggaa agttatttgt tggtggttta aaggctatcg cacctttgct tgtatttgct
    13561 ttggtttccc aagccatctc ccatcagaaa aaagggaaac agactaatat gacattaatc
    13621 attgttctgt atttatttgg tacctttgcg tcagctttag tagcagtact gacagcttat
    13681 ctattccctt tgacgttagt gttaaataca cctgtaaata cagaattatc accacctcaa
    13741 ggtgttgctg aagtttttca gtcacttcta ttaaaattag tggataatcc gatcaatgct
    13801 ttagctactg ccaattatat tggtgtgcta tcatgggcaa ttatttttgg actagcatta
    13861 aaggctgcaa gtcaagaaac aaagcatctt ataaaaacag cggcagaagt tacttcacaa
    13921 atagttgttt ggatcatcaa tctggcacct attgggatta tgagtctggt gttcactacg
    13981 atttctgaaa acggtgttgg aatcttatct gattatgctt ttttgatact agttttagta
    14041 ggaacaatgg tttttgtcgc cttagtggtt aatccactta ttgcggtttt gattacacga
    14101 caaaatcctt atccccttgt cttgagatgt ttacgtgagt caggtcttac agcatttttc
    14161 acacgaagtt ctgcagccaa tattccagtc aatatgcaat tatgccaaaa aattggattg
    14221 agtaaagata cttattcagt gtcaattcca cttggagcaa ctattaatat gggtggggca
    14281 gcaattacca tcaatgtcct aacgcttgct gctgtacaca cttttggtat tcctattgat
    14341 tttctaacag ccctcttact tagcgttgtt gctgctgtct ctgcttgtgg tgcttctggt
    14401 gttgctgggg gatcgttgtt acttattcct gtagcatgta gtttgtttgg catttcaaat
    14461 gatcttgcga tgcaggtggt tggtgttggt tttattgttg gtgttatcca ggattcttgt
    14521 gagacagcct taaattcgtc aaccgatgtt ctttttacag ctattgctga aaatgctttt
    14581 tggaaacgta aaaaagccta gctaggttta acatagtaaa aaacatcctt ggaaaacgcc
    14641 aaggatgttt ttttattatt taagatagcc aaggtaatca aatttttcaa aggtgtggtc
    14701 attagcgatg gctacaatga tagtattcgg ttctaaaggt tcaaaaggtt tgacattggt
    14761 atctaaggtt ttaacttctt tttgacgcat gccaatcaca tttaactcat atttacgacg
    14821 aacatctagt tcggaaagag attgtccttc ccagctttta ggaatgacaa attcaatcat
    14881 ggaaatgcca tgttcgaggt agatgatgct ttcgatatga cgtcttaaca gatttgaagc
    14941 tacacgtttt ccagaatcac gttcaggggt gatgacttta gttgccccga tgccatatag
    15001 aacttcttca aaaattttat ttttagcctt ggcaataatg gttggaacac cgagtttttt
    15061 acagtgcatg actgcaagaa cagaagattc caagttattc cctgaagcga taacgacagt
    15121 atcacaatgt tcaatcccta cagctaatag aaattctttg tcagtaatat ctccaacagc
    15181 ggctttagtg accaagtcgg ccacctcttt aacatgactt tctctgatat caatagcaat
    15241 aacgtcttga tcaaaattac ttaattctct ggcaacagta cggccaaaaa taccaaggcc
    15301 aagaacgccg acagttttac gttttaacat gttttctcct taacccacta aaatatcagt
    15361 agtggcatat tgaatggttt tttcttttcg ttgaatcaga ctgatgagga cagtaattgg
    15421 gccaacgcgg ccgacgaaca tcaagacaat gacaataaga cgtccagcag tagacaattg
    15481 tggtgtcaaa tccatagata ccccaactgt cgcgatggca gaaatagatt caaataagag
    15541 tggtatagga gcgatatgag gctccacgct aagtaataaa ataaaaccta tcataagaac
    15601 tgcaaaaaag aagataagaa ctgtcatggt ctgcttaatt gtcttatttg cgataattcg
    15661 gttacgaaag gtaacttctg attgccctga aagttccgct ttaaagagta agaaagtaat
    15721 ggcagcagtc gtcactttaa taccaccagc tgttccacca ggagcaccac caataaccat
    15781 ttgaatcata taaagaatgt tagtcggtgc tagggtatcg ttataagaga ttgttgcaaa
    15841 gccagctgtt ctcatagtga ctgtttgaaa aaatgaaacc ataagttgct gatgtaaact
    15901 aaaattggca atggttttgc tgttatcttt ttctaaaaac caggttaaga aggttccaag
    15961 aaaaagaata acagctgtgg tttgtagtac tagacgagac tgattggata atttacgaaa
    16021 agttgcccca taacaatgag gtctttcaaa aaagtatttt ttaaaagcta ctcctaaatc
    16081 aacccaaacc gcaaaaccaa gtccaccaga gataatcaag aacgtaatga taacatttaa
    16141 tgtaggattt aacataaagt cttttaaact agaagatcct aaattgtcaa aaccagcgtt
    16201 acaaaatgcc gacacagcta gaaaaatact attgaagata ccatttttcc acccgaagcg
    16261 ggggataaag tcaatcatga taactatcgc agcaaaggct tctatactaa aggttacttt
    16321 ataagcaaaa aaaaggtagt gctttaaatc tttgctatca cctcgattta acgctgattg
    16381 gagcaaggtt tgatcgctca atcgcatttt tcgcttgagg gcaaaagtac tcacagctat
    16441 taacgtcacc aagccaagac caccaatctg cattagtgcc atagcaatgg tttgtccgat
    16501 accgttatat acttcagcga cgggaacaac agaaagtcca gtcacacaaa ccatggaaac
    16561 cacattaaag aaatgatcaa gatagacggt attaggacca ttttgataat gggtaaaggg
    16621 catggataac aagagagtcc caatcagaat cacaatggca aaactaaatg ttaagcgctg
    16681 tgtgactgaa agagatttga taaaagagcg tttcatgttt cctccagaca taatatctcc
    16741 tactataata acaaaaataa gttaaaaaag ctaagtttca tcttagcctt tggtactatt
    16801 ttatagaggt tttttgttag gcaagccagc ttttcttgga tacttgttag gtgtttcctt
    16861 tttcttctca acaatggtga tgaagcgaga atctccattt ggcaattggt agctatggtt
    16921 tttaatgact ttaccaaaaa gaagacaaag agcattctta gcttcttcta actcttggtc
    16981 agcagcttgt gcctttaagg cgattaattt tcctccaatt tttaaaaagg ggatggttaa
    17041 ttcagataga acctgcatcc gagcaaccgc tctggcagta acgacatcaa attgacctcg
    17101 aaaggccttg tcctgtccga aatcttctgc tctaccatga aaaaaatgga cattttccaa
    17161 gcccaattcc tgagcaagga gtgtcagaaa agaaatccgc ttattaagag aatcaataat
    17221 ggtaacctca aggttcggga aaagaatttt catgggtagg ctaggaaaac cagctccagc
    17281 tccaatgtcc aataatttga ttggttcatt agctaaaaag gcctgtaaaa taggagcgat
    17341 ggaatcataa aaatgcttga ggtaaacctc attttcttct gtaatagctg ttaaattaat
    17401 tttagtgttc cattccacta gtaatttaaa gtaggtgtca aattgttctt tttgtttcga
    17461 tgataaggaa aaaccatctt cctctagtgt tcggtaaaag tcttggggtg tcatttgtat
    17521 cctctgtttt tgatagttgt taccatttta tcataaaata gcccataaca aaatccaata
    17581 aatcatcaga aataacacct cattacttgc tattagccta gaaattgcta taattgagac
    17641 acaaagatta aaggagaccc actatgccaa cagttttgat tatcttagtc gttttaggag
    17701 tgcttgcgct atggttaatg attagttaca atagcctggt taaatctcgg atgcacacaa
    17761 aagaagcttg gagtcagatt gatgtgcaat taaagcgtcg taatgacttg attccaaatc
    17821 ttattgaaac cgtaaaggga tatgctagct acgagcaaaa gacatttgaa aaaatcactg
    17881 atttgcgtgc gcgtgttgcg aatgcctcaa ctcctcaaga aaccatggcg gcttctaacg
    17941 aattgagtaa acaagtgacc agtttgtttg ccgttgctga aaattaccca gacttaaaag
    18001 ctaacgaaaa cttcttgaaa ttacaagaag agttgaccaa tacggaaaat aaaatctcat
    18061 attctcgtca actctataat tcaacaacgt ctaattacaa ccttcaatta gaatctttcc
    18121 caagcaatat cgctggtaaa ttatttggtt ttaaaccaag tgaattctta caaacaccag
    18181 aagctgaaaa agaagttcca aaagttgaat ttaactttta aatatgaaat tatcatctag
    18241 taggcaatca taagagaaag gagaattatg ctttatcaac agatttcaca aaataagcaa
    18301 cgaacagttg ttttattagt tgttttcttc gctctcttag cacttattgg agcgtcagca
    18361 ggctatctgc tgttagataa ttatgccatg ggcttggttc ttgctcttgt cattggggtg
    18421 atttatgcta ccagtatgat ttttcaatcc accagtcttg taatgagtat gaacaatgct
    18481 agagaagtta cagaaaaaga ggctccaggc ttcttccata ttgtcgagga tatggctatg
    18541 gtggctcaga ttccgatgcc gagagttttt attattgaag atccttcttt aaatgctttt
    18601 gcgacaggat ctagccctca aaatgctgct gttgcagcaa cgacaggttt acttgaagtt
    18661 atgaatcgtg aagaacttga aggtgttatc ggccatgaaa ttagccacat ccgaaattat
    18721 gatatccgta tttcgactat tgctgtagct ttggcgagtg ctgttaccgt tatttctagt
    18781 atcggtgggc gtatgctatg gtatggtggc ggttctcgca ggcaaagaga tgacggagat
    18841 gatgatgttt taagaatcat tacgttactt ttgtcgttat tatctttgct tttagcgccc
    18901 ctagtagcaa gtttgattca gttggctatt tctcgtcaaa gagaatatct agctgatgct
    18961 agttctgttg aactaacaag aaatccccaa ggtatgatta aggctcttga aaaattgcag
    19021 ttatctcagc caatgaagca tcctgttgat gatgctagtg cggccttgta tattaatgag
    19081 cctcgcaaaa aaaggagctt cagttcatta ttcagcaccc atcctcctat tgaggagagg
    19141 attgaaaggt taaaaaacat gtgagcgttt ggggtttttg ctcaagcctc acttttttat
    19201 gtctttgggc agataatcta aaatggcagg aattatcaaa aatatctgaa caaaaagaaa
    19261 aaaatgagtg aaacaatggt taaaaataga atgatttaaa tcttaaaatt aaaaaacgtc
    19321 agaaaataaa tgcaaaacta ttgacaaatc ttttagatag tagtaaaaat aaatgagagt
    19381 tttattagga gaagatgatg ttagctattt ccgaaatcag aaaacaccca gacggtctct
    19441 cgtttgatcg tttatgtgat gtcaaaagta tgttacttga gcgtgaccaa cagattattg
    19501 acataaaggc agttaaagct gtcggtaatg ttcgctatga taaggggctt tatctgttag
    19561 attatcaatt gagttacgaa gtgatattac cgtctagccg ttctatggtt ccggtctgtt
    19621 taagtgaagt ccaacacatt caagaattat ttatagaggc gacagattta gctgataaga
    19681 aagagttggt tgaagacaat ctggtattag ttttagacaa agacgctatt aacctcgaag
    19741 aaagtattgt ggataatatc ttacttgcta ttccgctaca ggtcttgaca gaggaagaaa
    19801 agaaatcaaa agagttgcca gcaggtcaaa attgggcagt tttgacagaa gaagactacc
    19861 agtgtctaaa agaagaaaag caaaaagaaa ataatccttt tgctagcttg caagggttgt
    19921 ttgatgaata aaactgaata ttaaagatgt ctgtaatttt tatttgaaaa aacagctatt
    19981 ctttgatata ctctttagag aatatggtta cttatctaaa gtagaaggta ttttgaccat
    20041 agagggcaaa gaaggtaatg actattagat gcttcatatt ttattcgcta gaagactatt
    20101 tgaccattag aactgaaata gtctaggata tgagatggat ttcatagttt tctttctggg
    20161 agaaaaagat agattaagag gataagggtt ggtataaatg acaaagaaga ttttaattat
    20221 tgaagatgaa aagaatctgg ctagattcgt ttctcttgag ctgcaacatg agggttatga
    20281 agtcattgtt gaggtcaatg gtcgtgaagg gttagaaact gctttggaaa aagagtttga
    20341 tttaatcctg cttgacttaa tgttaccaga gatggatggt tttgaagtga cccgtcgttt
    20401 gcaaaccgaa aaaacaacgt atatcatgat gatgactgcg cgtgattcta ttatggatgt
    20461 ggttgcaggt ttagaccgcg gtgcagacga ctatattgtt aaaccgtttg ccattgaaga
    20521 actacttgcc cgtattcgtg ctattttccg ccgtcaagat attgaatctg agaagaaagt
    20581 gcctagtcaa ggcatttatc gagatctagt tttaaatcca caaaaccgtt cagttaatcg
    20641 tggcgacgat gagatttctc tcactaaacg tgaatatgat ttgcttaata ttttgatgac
    20701 taatatgaat cgtgtcatga cacgtgaaga attattgtca aatgtttgga aatatgatga
    20761 agctgttgag actaatgttg tagatgtcta tattcgttat ctccgcggca aaattgacat
    20821 tccaggcaag gaatcttata tccaaacagt gcgtggcatg ggatacgtta ttcgtgagaa
    20881 ataagtcata tggaaaatca gaaacaaaaa cagaagaaat ataaaaactc gttaccaaaa
    20941 cgactatcta atatcttttt tgttcttttt ttctgcattt tctctgcctt tacactgatt
    21001 gcctatagtt caacaaacta tttcttattg aagaaagaaa agcagtcagt ctttcaagct
    21061 gtaaatattg ttagagttcg tctttctgag gtggactcta attttacatt agagaactta
    21121 gcagaagttt tgtacaaaaa cgataaaaca catctgagaa ttgatgacag aaagggcagt
    21181 cgagtcatta ggagtgagcg cgatatcaca aatactctag atgcgaatca agatatttat
    21241 gtctataaca ttgataaaca gatgattttt accacagata atgaagaatc atctcctggc
    21301 ttgcatggtc ctatcggtcg ggtgtatcac gaccatatcg aagatcagta tcgtgggttt
    21361 tccatgacac aaaaggtata ttctaatcgg actggaaaat ttgtgggcta tgttcaagtc
    21421 tttcatgatt taggcaatta ttatgtcatt agagcaagac tgctgttttg gctactagtt
    21481 gttgagttat ttggcacaag cttagcctat ttaatcatct taattactac gcggcgcttt
    21541 ttgaagcctt tacacaattt acatgaagta atgcgtaata tctctgaaaa tcctaataat
    21601 ttaaacctgc gctcagatat ttcgtcagga gatgaaatcg aagaattgtc tgttatcttt
    21661 gacaatatgt tagacaaatt ggagacacat actaagttgc aatcacgttt tattagtgat
    21721 gtcagccatg aattacgaac accggttgcg attattaaag ggcatattgg tctcttacaa
    21781 cgttggggta aagatgacag tgatattctt gaagaaagtt tgacagcaac agcgcatgag
    21841 gctgaccgta tggcaatcat gattaatgat atgttagaca tgattcgcgt acaaggctca
    21901 tttgagggac atcaaaatga tatgacagtt ttggaagatt ctattgaaac tgttgttggt
    21961 aattttagag ttttaagaga agattttatc tttacatggc agtcagaaaa tccaaaaacg
    22021 atagcccgta tttataaaaa tcattttgag caggctttga tgattcttat tgacaatgct
    22081 gtgaagtatt cccgtaaaga aaagaaaatc gcgattaacc tttcagtgac tggcaaacaa
    22141 gaagctattg ttagagttca agataaaggc gaaggaattt ctaaagaaga tattgaacat
    22201 atctttgaac gcttttatag aacggataaa tcacgtaatc gaacaagtac tcaggctgga
    22261 ttagggattg gcttgtctat tctcaagcaa attgtagatg ggtatcattt acagatgaag
    22321 gttgaaagtg aattaaatga aggttcagtg tttatcttac atattccttt ggcccagtct
    22381 aaagagagtt agagtagctt aaggcattgt taatgtgaca ggtatagtat gtaatcatta
    22441 gataatagta gcagtctttt gccacaactg gttagaagct gatgctattt ttttagcaat
    22501 gatggatgac atgaaagaaa tactgtcaat cgcgatgcct tttgttatcc ttgagaatat
    22561 ggtaaaatag tgtattagat taatttgata gaattggggt gtttgcgtgc gttgtccaaa
    22621 atgtaattac cataaatcga gtgttgttga cagtagacaa gctgaagacg gcaacaccat
    22681 tcgtcgtcga agagaatgtg aacagtgtca tactcgcttt actacctttg agcgtgttga
    22741 agaactccct ttattagtca tcaaaaaaga tggcacacga gagcaatttt ctagagataa
    22801 aatattaaat ggggttgtcc aaagtgcgca aaaacgacct gtctcgagca cagatattga
    22861 aaatgtcatt tctcgtattg aacaagaagt tcgaacaacc tacgaaaatg aagtgtcaag
    22921 tactgctatt ggtaatttag tgatggatga gttggccgaa cttgatgaaa tcacatatgt
    22981 acgctttgct agtgtctaca agagcttcaa ggacgttgat gaaatcgaag aacttttgca
    23041 acaaattacg aatcgcgtac gcggaaagaa aaaacgttta aataatgatg aaaccaattg
    23101 atacttttac atatctaaaa cgcaacaaag taactcttga ttcggtgact ttaatacagt
    23161 tgtactttcc aattattgga agtgacgcag tctctatcta tcaatacttt attcactttt
    23221 ttgacgatgg tttacaacgt cataaattca gcgatatttt aaatcaccta cagtttggta
    23281 tgaaacgttt tgaagatgct cttgccatat tgacagcaat ggaattagtg agtgtgtatc
    23341 agctatcaga tacatatctc attacgttgc accagccgct tagccgtgac ttgttttttc
    23401 aacatccagc ttattctcga ttattagaac aaaagattgg agaggtagct gtctctgagt
    23461 tgcaggtaac tgtcccaagt caagcaagaa atatttctaa gcgattttcg gatatttttg
    23521 gggtgcaagg agatttgacg aacgtacctc aaaagccaca aaagaatttt gacctttcaa
    23581 gtttccagca attaatggtt cgtgatgggt tacaatttga agataatcaa aaagatatca
    23641 tcagccttta cagtattgct gaacagtatg atatgacgtg gtttgatact tatcaaatag
    23701 ctaaggcgac ggctgttaat gggaaaattc gacctgaacg cttattggct aaaaaaaatc
    23761 aaagcatgac aaaaccaagc aaagaaaatt tttcacaggc tgagcaaatt attttgcgag
    23821 aagcaaagca agacagtgct ttagtctttt tggaaaaaat taaaaaggct agacgtgcaa
    23881 cgattactaa ggatgaacgc attttattgc aaacattggc caaaatgaat tttcttgatg
    23941 atgttatcaa tgtcatggtg ctttatacct ttaataagac aaaatctgct aatttacaga
    24001 agagttatgt cttaaaaatg gccaatgatt ttgcctacca aaaggtgtca acggctgaag
    24061 aagctatagt ggttttgcga gccttcacgg atcgtcaaag tcgtcggcaa tcaaaagtaa
    24121 aaacaagtca aagcaatgtg cctaagtgga gcaatcctga ttaccaagag acaacaagtc
    24181 aagaagagca ggcgaaacta gatcagttca aacaggctgc tttgaagagg ttagaaaacc
    24241 taggaaaagg gggtgactag atggaaaaga ttggagaaac catggcgaaa ttgggtcaaa
    24301 acactcgtgt taatagcgac cagttgattc aaaccatttt agcggatcct gaagtagcaa
    24361 gcttcatcag tcaacatcac ttatctcaag agcaaattaa ccttagctta tctaagttca
    24421 atcaattttt ggtggaacgc cagaagtatc aactcaaaga tccctcttat attgctaagg
    24481 gctatcagcc tattctagct atgaatgagg gctacgctga tgtgtcttat ttggaaacca
    24541 aagaattggt agaagctcaa aaacaggcag ctatctctga acggattcaa ctggttagtt
    24601 tgccaaaatc ctatcgccat attcatttat cagatattga tgttaataat gcgagccgta
    24661 tggaagcctt ctctgctatt ttagattttg tggaacaata cccatcagca gagcaaaaag
    24721 gcttatattt gtacggagat atgggaattg gcaagtctta cttgttggct gctatggccc
    24781 atgaattgtc tgagaaaaaa ggtgtgtcaa cgacccttct acattttccg agctttgcca
    24841 ttgatgtaaa aaatgccatt tcaaacggct ctgttaaaga agaaatcgat gcggtcaaaa
    24901 atgtaccagt gctcatttta gatgatattg gtgcagagca agccacttct tgggtccgtg
    24961 atgaggtgtt gcaggtgatt ttacaatacc gtatgttaga ggaattgcca accttcttta
    25021 cctctaatta cagctttgcg gatttggagc gaaaatgggc aaccatcaaa ggaagtgacg
    25081 aaacttggca ggccaaacgt gtcatggaac gcgtgcgtta tttggctaga gagtttcatt
    25141 tagaaggggc taaccgccgt taagtttgag atagcaatca agaagaatag ctacacgtat
    25201 gagtgagtga aagaaaagga gaatcatggt tttacctacc gttgccattg tgggccgtcc
    25261 aaacgtgggc aagtccacct tatttaatcg aatcgcagga gagcgcattt caattgtaga
    25321 agacgttgaa ggggttactc gtgaccgtat ttatgctact ggggagtggc ttaaccgcca
    25381 attttcattg attgatacag gtggtattga tgacgttgat gccccgttta tggagcaaat
    25441 caagcaccag gctcaaattg ccatggaaga agctgatgtt atcgtttttg ttgtttctgg
    25501 caaagaaggg gttacggatg cagatgaata tgtgtctaaa atcctatacc gaaccaatac
    25561 tccagtgatt ttagctgtca acaaagtgga taatcctgaa atgcgtaatg acatttatga
    25621 tttttattca cttggtttag gggatcccta tccagtttct tctgttcatg gtatcggaac
    25681 aggggatgtc ttggatgcga tcgttgaaaa cttgccagta gaagaggctg aagaaaatga
    25741 tgatattatt cgcttcagtt taatcggtcg tcctaatgtt gggaaatcta gcttgattaa
    25801 cgctatttta ggtgaggacc gtgttatcgc tagccctgtc gcagggacaa cacgtgacgc
    25861 tattgacacg cattttacgg atgctgacgg tcaagaattt accatgattg acacggctgg
    25921 aatgcgcaaa tctggcaaga tttacgaaaa tacagagaaa tattctgtca tgcgtgccat
    25981 gcgtgccatt gaccgctccg atgtggtctt gatggttatc aatgctgaag aaggtatccg
    26041 tgaatacgac aagcgtatcg ctggctttgc acacgaagct ggtaaaggaa tgattatcgt
    26101 ggttaacaaa tgggatacca ttgacaagga taatcatacc gttgctaagt gggaagccga
    26161 tattcgtgac caattccaat ttttgacata cgctccgatt atttttgtgt cagctttgac
    26221 gaagcagcgc ctcaacaaat tgcctgactt gattaaacgt atcagtgaga gtcagaataa
    26281 acgtatccca tctgctgtcc tcaatgatgt tatcatggat gctattgcca ttaatccaac
    26341 gccaacggat aagggtaaac gtttgaaaat tttctatgcc actcaagtgt cagtaaagcc
    26401 accaacattt gtcgtctttg ttaacgaaga agaattgatg cacttctctt atctacgctt
    26461 cttggaaaac cagattcgcg cagcctttac ctttgaaggg acaccgattc atctgattgc
    26521 tcgcaaacgg aaataagaaa tgaacatcaa ctaaaatgct gacctaagaa ataatctcat
    26581 cattgataag gactgtgttg tgtatgttac aggagacagt cctttttata atacctttaa
    26641 gggtgtagac ggaagattag tagcaaacaa agaaaaagga ttttgacaag aaatatcagt
    26701 cggtttttgc tataatgaaa ggataagcaa aaaggtggaa aaatgatggc tagattaatt
    26761 ccaggacgag taaggaatga aggtattaag ctttatgagc aaggtttagt ctcattccaa
    26821 gatgataata aaggcattct tcaaatagaa gtggagactt atcaggttca atatggagca
    26881 gatgatgagg atatcacttg tcaatgcgac acatttcata tgaaacatta ttgcaagcat
    26941 attgcagcag tcgagtattt tttaaaaaat gatcaaaaag gtaagctttt tttaaaacag
    27001 ttaacaaatc aaacaaaaat caaagaaaca acaaagaaaa tgacatcttt tggtagtctc
    27061 tttttagata gcttagccat gaatgaagat gattctgtta aatacaggct gtctgctctt
    27121 ggtagtcgaa gccctttttc gtcagattac tggtggagtc tgaaaatcaa tcgtttacca
    27181 gatgatcgtt cttatgtgat tcgagatatt aaaggctttt tgcagcttat taaaaaagaa
    27241 ggcttttatc agattggaaa aaattatttt gaacaacttt catggctgca gtttgaccca
    27301 tccagtcaag accttattga gtttttatgg cgcttagcat ctaatactga caaaggggac
    27361 aacgagaaca tttttccaaa tcatgcaagg catttgcgct tacctagtgg tttttttgaa
    27421 gaaggtattc actatttgac gtcactttat gactttactt ttgaggggcc ttctcaaact
    27481 tatcatcatc tttttgtccg ttctttggaa gcagaggcag gcctttatga gtttaaagtg
    27541 gaagtgtatc gcaaatctat tgaattgcaa attgctgaaa aaaatgtgca atacctcttt
    27601 gataatgact atcttcttta tcaagatacc ttttatcact tgacgttaaa gcaacgaaaa
    27661 atggttcagg ctattcgtag tctgcccatt gaggccgact tggctaaaca tattcatttt
    27721 gatttggatg atcatgcgaa attagctgca agcttatcag attttaaaca gatcggtcta
    27781 gtagaggctc ctaaaagctt tgctattaga gactttgagg tgacttttca atttgatttg
    27841 ttaaatcgag atgaaatcag ttgtcagctt atgtttgatt atggcaatta ccaagttagt
    27901 gacaaagcaa gtttagaagc acttcctttt gctagtcatt taaaaaaaga agaaaaaatc
    27961 aatcgttctt tacttgcttt tggcttctcg ccacaatttt actcaaaaaa gcgactaaca
    28021 agtgcaaaag agctctatac tttttttgaa gaaacagttc catgttttga gcgcttaggt
    28081 aatgttgcgt tgagtacagc tatccaagca ttacaagtga aagaaatgcc caagatcgct
    28141 attagacgca atcagggatt actagatatt tcgtttgatt tttcaaccat tattgaaaat
    28201 gatattgacc aagctgttac agctcttttt caaaataatc cttattttgt gagtcaaaca
    28261 ggtcaattag tggtttttga tgatgaaact caaaaagtta gcaaaagttt acaagaatta
    28321 agagcaagac agctaaaaaa tggtcacttg caactggatg gcattagagc tctacaagta
    28381 tccaaacttt ttgaaggcat gacatctgtt catttttcaa aggaattaga agagttagcc
    28441 tatcatttgc agcatcctga aactttttca ataaaaccgt taccagttaa ggctcaaatg
    28501 cgagattatc aacgcaacgg tgttcagtgg ttatcaatgc tcaatcatta tggctttggt
    28561 ggcattttag cagatgacat gggacttgga aaaactctcc agacacttgc ttttttagct
    28621 agtcacctga aatcagatag taaagtgctc attttatctc catctagtct tatctataat
    28681 tggtttgatg aatgtcaaaa attcacacct cagctagatg ttgtagtttc ttacggactt
    28741 aaacaaatca gagatcaaat catcgaagaa ggtcatcaaa taaccataac cagctattcc
    28801 tcctttagac aggattttga gacctatcaa gcgtttcact acgattatct tatcttagat
    28861 gaagctcaag tgataaaaaa tgcgcaaact aagatttcac actgtttacg tgcgtttaat
    28921 acagccaatt gttttgcgct ttcgggcact cctattgaaa ataaaatgct tgaaatttgg
    28981 tccattttcc aaattgtttt gccagggttg ctaccgacta aaaaagagtt tttaaaatta
    29041 acagctgagc aagtatcgcg ctatatcaaa ccctttgtga tgcgtcgtaa aaaagaagat
    29101 gtcctaccag aattacctga tttaattgaa actaattatt caaacgagat gacagatgaa
    29161 caaaaagcta tttacttagc gcagttaagg cagatgaaag atcaaattcg aaattctagt
    29221 gatgtggata ttagccgtca aaaaattgag attttatctg gtatcactcg attgaggcaa
    29281 atctgtgaca ctccaagtct ctttatggat taccaaggca aaagtggtaa gctagatagt
    29341 ttgcgaatct tattgacaca aattaaagaa aatggtcatc gggctttgat tttttctcaa
    29401 tttagaggga tgctggactt ggccaagcaa gagatgactg ctctaggatt gacctcttat
    29461 caaatgacgg gatctacccc tgccaatgaa cgtcaagaaa tgactagagc ctttaataac
    29521 ggttccaagg atgctttttt gatttccctc aaggcaggtg gagttggaat caaccttccg
    29581 ggagcagaca cagtgatttt aatcgattta tggtggaatc ctgctgttga aatgcaggca
    29641 atcagtcgcg cctaccgtat tggtcaaaaa gaaaacgttg aagtatatcg cttaatcact
    29701 cgagggacga ttgaagaaaa gattttagag cttcaagaaa gtaagcgcaa tttggtgact
    29761 acagttttgg atggcaatga aagccgagca agtatgtcca ttgaagaaat aaaagaaatt
    29821 ttggggctaa acactcatta atcttccttg attttagtga cattaaaaac cctttaaaga
    29881 agatgacacc aaaagcacct tatataacct cgttaaaacg cttctttttg aaatatcttt
    29941 attgatatag cgattgtcat ttgctagtaa tgattaaaac atttagaaaa agacaagtca
    30001 tagaatcatc aaggaatgct ttgaaaaata acagtattta agttataata gaggatgcta
    30061 caagaaggga gaatcaaaaa aggatggtaa aaaatcagtt tcctttagtt gcagatggca
    30121 ttgctattag tgatccagca aagcaaatgg ctctgtatga aaatgaagat ctcattacca
    30181 acatccgtgg ctattaccag gacaaggagt atgatgatat tgctagaaat gaggagttta
    30241 ctgctaaagc aacttctcgg caggcccctt ctagtaagcg cttttgtagc aatgatgaaa
    30301 aacaccatta tgtcaaagag gcgcgtcaaa aagcaaagca agatctcaag gaaaaaagac
    30361 aggcttatct tgccaaagaa atggcctatg ttcctaaaca ggtttctaaa aagcaacagc
    30421 ctgcggattc ttctccttct caaaagcaag caacaacaga aatgagtcgt tttacaaaaa
    30481 agcttcatca agacaactat attttagctg agttgccaaa agaatataaa gagccaaaaa
    30541 atcttcctca acaaggaact acaaaaaaaa ataattacga ttttttaaaa tccagtcaaa
    30601 tttacaataa taaagaaatg agacaacaac gagaaaaaac aattgcgcaa gagcttaatc
    30661 ttagtaggtt tgaggatctt ccttaataaa tctactcagc gtatgcagat gacaaaggag
    30721 ttaagatgtc aaaaacgtat cattttatcg gaattaaagg gtcaggaatg agtgccttgg
    30781 cccttatgtt gcatcaaatg gggcataagg tgcaaggtag tgatgttgaa aaatactatt
    30841 tcactcaaag aggattggaa caagcgggca tcactatctt accttttagc gaggacaaca
    30901 ttacgccaga tatggaactt atcgttggga atgcctttcg tgaaaacaac aaagaagtgg
    30961 cctatgcttt gagacaccag attcctttca aacgttatca tgacttttta ggtgatttta
    31021 tgaaatcatt tatcagtttt gcagtagcag gtgctcatgg taaaacttct acaacgggtt
    31081 tattgtcaca tgtcttgaaa aatatcacag acacatctta tttaattggt gatggtactg
    31141 ggcgtggatc tgctaatgca cagtattttg tttttgaatc agacgaatac gaacgccatt
    31201 ttatgcctta tcacccagaa tactctatca ttactaatat tgattttgac catcctgatt
    31261 atttcacagg aattgctgat gtgcgaaacg ctttcaacga ttatgctaag caggtcaaga
    31321 aagctttgtt tgtttatggt gaagatgacg aactaaaaaa gatcgaagca cctgcaccta
    31381 tttactatta tggttttgaa gagggcaatg attttatcgc ttacgacatt acgcgtacta
    31441 cgaacggatc ggactttaag gtaaaacacc aaggagaggt cattggtcag tttcacgtac
    31501 ctgcttatgg aaaacataac attttaaacg ctacagcagt aattgcaaac ttgtttgtag
    31561 ccggcattga tatggctcta gtggcagacc atcttaaaac tttttcaggt gtgaaacgtc
    31621 gttttacaga gaaaattatc aatgacacta ttattattga tgactttgct catcatccaa
    31681 ccgaaattgt ggcaacaatt gatgcggcta gacaaaaata cccaagtaaa gaaattgtag
    31741 caatatttca gccacatact tttactcgca ctattgcctt attagaggat tttgcttgtg
    31801 ctttaaatga agctgacagt gtttatttag cccagattta tggttctgca cgtgaagtag
    31861 ataaaggtga agttaaggtt gaagatttgg ctgctaagat tatcaaacca tcacaagtag
    31921 taacggtgga aaatgtctct cctcttcttg atcacgataa tgctgtttat gtttttatgg
    31981 gagctggaga tattcagcta tatgaacatt cttttgagga attacttgca aatttaacta
    32041 aaaataacca ataacatgtc ctgccttagg caggttttct cattctaaag gagtttgata
    32101 tgttgattag acaggttcaa ggatccgatt tggaagttat tgctaccatt gaaagtgaca
    32161 atttttcacc acaagaagca acgacaagag cagttcttga agagcgcata cggctgatac
    32221 cagatacttt tttagtggca cttatcgatc aggaaattgt tggctatatc gaaggtccag
    32281 ttgtcactac tcctattttg gaggattctt tgttccacgg ggtgactaaa aatcctaaaa
    32341 ctggaggcta tattgctatt actagtttgt ccatagctaa acattttcag caacaagggg
    32401 ttgggacagc tttgttggcg gcactaaaag atttagtagt agcgcagcaa agaacaggtc
    32461 ttattttgac ttgtcatgat tacttgattt cctattatga aatgaatggg tttattaacc
    32521 aaggaatttc agagtctcaa catggtggaa ccctttggta ccaaatgatt tggaaacttt
    32581 agaatcacag ctgattcaac tgttggtttg ttaaaaataa gtaacaaatg catcatttaa
    32641 ttgcaattag gatactttta agttataatg gcggttgatt atatttagga ggattggctt
    32701 tgaccgattt taaggataaa gaccaacaag atcagcagcg aagctttaaa gagcagattc
    32761 ttgctgagtt ggaaaaagca aatcaaatca gaaaagaaaa agaggaagaa ctttttcaaa
    32821 aagagttgga agctaaagaa gcagctaaga gaacggccca gctatatgct gaatataaaa
    32881 ggcaagatgc ttttcaaaaa gagtctatag cacataacaa taagacagct aaacactttc
    32941 aagctataaa aggtgcggta atgacttcag aagcgcttaa accgacttta ctttctgaaa
    33001 aagaaaactc atctttaaaa acgacaaata agagagtcgt gcaggcaaat gagcttcaag
    33061 agactgcctc taaagaatct caagtaccgt taactattga gaaaggtcat tcagtgagac
    33121 gaaaattaag caaacgccaa cagactgagc gagctgctaa aaagatttca accgttttga
    33181 ttagttctat tattataacc cttttggctg ttactctagc aggagcaggc tatgtttata
    33241 gtgctttaaa tcctgttgat aaaaatagtg atgcctttgt tcaagttgag ataccatctg
    33301 ggtcaggcaa taaattgatt ggtcaaattc ttcaaaaaaa aggtttaatc aagaatagca
    33361 ctgtttttag tttttataca aaatttaaaa actttacaaa ttttcagagc gggtattaca
    33421 atctgcaaaa aagtatgagt ctagaagaaa ttgctagtgt tttacaagaa ggtggtacag
    33481 cagaacctac caagccatct cttgggaaga tcttgattcc agaaggatac acgattaaac
    33541 aaatagctaa agctgttgag cataatagca agggaaagac caaaaaagct aaaacacctt
    33601 ttaacgagaa ggattttttg gatttagtca cagatgaggc ttttattcaa gatatggtaa
    33661 aaagatatcc aaaattatta gcaactatcc caactaaaga aaaagctatt taccgtttgg
    33721 aaggttacct tttcccagca acctataact attacaaaga aactaccatg agagaacttg
    33781 tagaggacat gctggcagct atggatgcta ctttggtacc ctattatgat aaaattgctg
    33841 ctagtggtaa gacagtcaac gaggtattga ccttggcctc tttggttgaa aaagaaggtt
    33901 caacagacga tgacagacgt caaattgcaa gtgtctttta taaccgcctt aatagcggaa
    33961 tggcactaca atctaatata gctattttgt atgcgatggg gaaacttggt gagaaaacaa
    34021 ccttggctga ggatgctact attgacacca ccattaattc tccttataat atttatacca
    34081 atacaggtct gatgcctggt ccagttgcta gctcgggggt ttctgcaatt gaagcaaccc
    34141 taaatccagc ctcaacggat tatttatact ttgtggccaa tgtccatact ggtgaagttt
    34201 actatgcaaa aacatttgaa gaacactctg caaatgttga aaaatatgtg aatagtcaaa
    34261 ttcagtaaac acaaacatgg tgcttaagca ccatgtttgt gtttctgatt cgttcaaaaa
    34321 agaaaagaga gaaaacaatt atggcagaaa aaacgtatcc gatgacccta acggaaaaag
    34381 aacaacttga aaaagaactt gaagaattaa aacttgtgcg tcgtccagaa atagtggagc
    34441 gtattaaaat tgcacgttcg tatggagatc tttcagagaa ctctgaatac gatgccgcaa
    34501 aagatgagca agcttttgtt gaaggtcaaa tttcaacgct tgaaactaag attcgctatg
    34561 ctgaaatcat tgacagtgat gctgttgcaa aagatgaagt cgctatcgga aaaacagtta
    34621 tcgttcaaga agttggaaca acagataaag atacctatca tattgtaggt gctgctggag
    34681 cagatatctt ctcaggaaaa atttcaaatg aaagcccgat tgctcaagct ttgattggta
    34741 aaaaaacagg tgacaaggtt agaattgaat caccagcagc tacttatgat gttgaaatca
    34801 tcagcgttga aaagacaaat taatcagatg aagccattat ttgcctaacc cctaagtgtt
    34861 ttggttgcta atggcttttc tagtatcttc aaatgaggtt gactgttagg aaggtcaagt
    34921 attaatcgca ttgattatga gccaagagga ctatagatca aagatcgttt tcgatggtta
    34981 tttaatacca aaagaaaaga ccagcacctt aatgtactga ccccaaaaag ttggacacta
    35041 tattttaagt ataggaagtg tataatctaa ggaaactgac actaatgatt gaccgttttg
    35101 caagacttta ttaatgattt cttgctttat tttaaatgaa taagtctgat acgtttcctt
    35161 ccttaacact atcgactcca taatgaccca tcagtcaaac ggtatatctc aaacgactac
    35221 ggtttactcc aaattgattg gctagttgag gccaagaaac acctgatttt tttaatgcta
    35281 aatttctagc ttatcttcat agcttaattt catacaaaaa caccccaatc gttagatttt
    35341 tttgatatgt cccctttcac tagatgagtc cagtaaaagg gggcatatcg ttttttgtct
    35401 aacttttgga gtgcagttca taattgtgct aggttttttg tctttcttaa cgctttcgct
    35461 gttttccagc attacgattg gattttattt ttttaggcaa gttagcctgt tccatgtttt
    35521 gtgaaggcgt aacatcctta cgagaagaag ttgattggta tgctttaggc ggggttttag
    35581 cgtattcttc tttaatttgc ttatgcaatc gaggttttaa gaggtaggtt gtgattaact
    35641 gttgaataat actaaagaaa ccaccaacta gccagtaaag accaacacca gcagggagtg
    35701 agaaggacat gaagatcatc atgataggca tggtgtacat catcgtcttc atttgctcac
    35761 gttgttcttc tgaaacggcc atcattgata accatgattg gaagaagtaa agagcagcga
    35821 taattgctgt taacactaaa ctacggctac caagatcaat gcccataaag gtacttgttg
    35881 atactccttt agtgtattga gcggcaaaat acatggcaga aaagaatggc atctggatga
    35941 gaagaggtag acatccaata cctccaagag ggttaatccc atgagcacgc tgagcagcca
    36001 tcaattctgt ttgggcagcc attttttctt cctgactact tgcctgtttg atacgtttgt
    36061 tgattggttc aaaaacaggt ttcaagaagg tcattttctc agattgataa cttgctttcc
    36121 aagattgata tagacctagt ggtaagataa gtgttctaac aataatggtt acgatgatga
    36181 tagccagtcc ataacctagt ccagcattgt ttgcaaagta atcgataaag tatgacatgg
    36241 gttttccaag aaattcccaa atcatacctt tgggatttcc gtgagcgtct cttcccacac
    36301 agcctgtcaa ggtgaataga attgacagtg ctagtcctga aaagaggatg cgatttaatg
    36361 ttagtttcaa tgtgtttatc ctttaatttt aatatactta tctattttac agtttttttc
    36421 agaaattcac aatagttctg aaggccgatt tttaattgcc tatttgaaag tcctgaaagt
    36481 cttcaaaatt agccatggtg acatccacat aagtgacttt tgcccatttg gatggtcctt
    36541 tacgaacttc ttgaataaat gtggctattt tatctgaatc ttttgattgg gccagaattt
    36601 caacggtccc atcgttgtta ttccagacac gaccataaat atctcctata tctagagcta
    36661 aagtatgggt agcgtatcga aaaccaacac cttgtacacg tccagaaaca attaaacgta
    36721 ctttttgcat aagaagggcc tccttgcttt tattatagca catacttagc aggaaatctc
    36781 tttagctaat tgtctacttc ctgtcacttt tactaaagac aagaatacaa aaatgagata
    36841 gttagtagta ctaacagtaa aagagatttg tctattttaa aaatagtatc aaaaaaaggt
    36901 cttttaggtc taaaacattg aactgacccc aaattgacca tctaagaagt tgatgctttc
    36961 aaatgctgtc gcgtatggta taataggcgc atggttatta catcaaaagc aaatcaacta
    37021 attaagcaaa caaaaaaatt attgcaaaaa aagcatcgaa aacagtccta tttgattgag
    37081 ggctggcacc tttttggaga agcccaaaaa tcaggacaag tttttcgcca catctttgtt
    37141 ttagaggaaa tggtggagcg tctagcaggt gagcaagaac tcgttattgt tagcccacaa
    37201 gtgctcaagg agttgactga ctctcctagt ccacaaggca ttgttgctga ggtggagata
    37261 cctaagttag cctttccatc agattacaaa gggaaatatt tggttttaga ggacgtccaa
    37321 gacccaggaa atctggggac catcattcgt acagcagacg ctgcacggtt tgatggggtc
    37381 tttctttctg aaaaatcagc agatatttac aaccaaaaaa ccctacgttc catgcaaggt
    37441 agccattttc atttaccaat ttggcgaaca gatgtctatc agctttgtcg agagctccaa
    37501 gagtatgaaa ctcccatcct agcaacaact ctgtcaaaga aatctgttga ctataaaagt
    37561 ctcacacatc atgaaaggtt ggctttggtg ttgggaaatg aaggccaggg cattagtgct
    37621 gaaatggcag ccctagcaga ccaactggtt catattacaa tgcctggtca ggcggaaagt
    37681 ttgaatgttg ccgtagcagc aggaatcctc attttcagct tgatttaagc taatatgata
    37741 taataaccaa gtgaggtaat tatgttatgc attatacaga agataaagaa tatatggaac
    37801 acgtcggtca tttgatcgct catcctcgct ttcaaaaatt gagtcatatt gttcagcacc
    37861 aacattcaac gcgtcttgaa cattctatca atgtttctta ttcaagttat aaattagcca
    37921 agcgatttgg ttgggatgct aaaagtacag ccagaggggg cttacttcat gatttctttt
    37981 attatgattg gcgcgtgacc aagtttaata agggtcatgc ctgggttcat cctcgtattg
    38041 ctgtacgaaa tgcgaaaaag ttaacagaac tcaataaaaa agaagaggat atcattctaa
    38101 aacacatgtg gggagcgacc attgcttttc cgcgttacaa ggaaagttat attgtgacaa
    38161 tggtagataa atactgggct gtcaaggaag cagtgacgcc tttgagacaa aaatggtcta
    38221 atcgacggtt tcttcaccgc aagaccctcc aaagtcataa tcgttaagta aaggagttat
    38281 tatgaacgat cacgttattt atacacaatc agatgtggga ttaaatcagt tttttgctaa
    38341 aatttatagt ctagtgggaa tgggagtggg tttgtctgct tttgtttctt atttgatgct
    38401 ttatccattt agagaaaatt taatctctat tcttgttaat cagccgatga tttactatgg
    38461 tgctgcgatt attgaactta ttttagtttt tgtagccagt ggtgcagcac gaaaaaacac
    38521 accagctgca ttgcccattt ttcttatcta ttctgcgcta aatggcttta ccctaagctt
    38581 tattattgtg gcatacgctc aaacgacagt ttttcaagca tttctttctt cagcagctgt
    38641 gttttttgcc atgtcaatca ttggtgtcaa gactaagcgg gatatgtcag gtcttagaaa
    38701 ggctatgttt gctgctttga ttggtgttgt tgtggctagt ctgattaatc tttttattgg
    38761 tagtgggatg atgagttatg tcattagtgt gatttccgtg ctaattttct caggtctcat
    38821 cgcatcagat aatcaaatga ttaagcgcgt ttatcaagca acaaatggcc aggttggtga
    38881 tggctgggct gttgctatgg ccttaagctt gtatttagat tttattaact tatttatcag
    38941 ccttcttcgt atttttggaa gaaatgatta acattaaaaa gtgagtataa ctactcactt
    39001 tttaatgtta acaggataag taaactgtaa ggaagaaatt cgagatagat ataagatgag
    39061 gctgctaaaa gacctagtgt taatttgtaa actctttctt tttttggtat actattaagg
    39121 attaaatacg aggagaatat agatagatat gtcaacagct atttggattt tattacttat
    39181 tgttgccctt ggggtaggtg tttttggtgg gatttttatt gcccgtaaac aaattgaaaa
    39241 agaaattggt gagcacccac gtttaacacc agaagctatc cgtgaaatga tgagccagat
    39301 ggggcaaaaa ccaagtgaag caaaaatcca acaaacttat cgtaatatca tcaaacaatc
    39361 aaaagcagcc gtatccaaag gtaaaaaata aaagctaatt gttatagggg aaacctttgt
    39421 gatagttaga agtgaacagt ctttgatctc aatgttcagt agcacttgtc ttatcagtta
    39481 gatttgtcaa ctgttcaggg tttaaaaaga aactcagttg gctatttcca actgagtttt
    39541 tcatatcgtc agtaaggaag taaaggtaat ggatacaaga ccaattgggt ttttagattc
    39601 tggtgtggga ggtctgaccg tcgtttgtga attgattcgt cagctccctc atgagaagat
    39661 tgtatatatt ggtgattcag caagagcccc ctatggtcct agacccaaaa aacaaattaa
    39721 ggagtatact tgggagctag tcaatttttt gctgactcaa aatgttaaaa tgattgtttt
    39781 tgcatgcaat accgcaacag cggtggcttg ggaagaagta aaagcagctt tagatattcc
    39841 tgttttaggg gttgtcttac cgggggcaag cgcagctatt aaatcaacga caaaaggcca
    39901 ggttggggtc atcggaaccc caatgacagt ggcttcagac atttatcgca aaaaaatcca
    39961 gctattagca ccatctattc aagtaaggag tcttgcttgc ccgaagtttg taccgattgt
    40021 ggaatcaaat gagatgtgtt cgagtatagc taaaaaaata gtttatgaca gtctagcacc
    40081 attagtcggt aaaatagata cccttgtact aggatgtact cactatccct tgttacgacc
    40141 aattatccaa aatgttatgg ggccatctgt taagctgatt gacagtggag cagaatgcgt
    40201 ccgagatatc tctgtcttat taaactattt tgacattaac ggtaattatc atcaaaaagc
    40261 tgtcaaacac cgctttttta caacagcaaa tcctgagatt tttcaagaaa ttgcctcgat
    40321 ttggctgaaa caaaaaataa atgtggagca tgtcacctta tgagtgaaaa aatttacgaa
    40381 tacaaagatg aaaataactg gtttatcgga aagatgactg gtcataattt aatatcgggc
    40441 tggggagtca aacacacgac aatcaaaaaa atagatgacc ttttagacgg tattgccgca
    40501 acgttagatt gggaaaatcc taaaggttac gatgtttcgg tggtgcgtta tcagtctcct
    40561 ttatctctca tcacctttat tatcgatatg attaaccaag aaacccagcg tgagattaag
    40621 gtgattcccc atgcaggcac gattttatta atggaaaatg cgaaactgct tgcagtttat
    40681 ctcccagaag gtggagtttc aacggctaca ttttttgcga ctagtgaaca gggatttggg
    40741 gatactattt taatcgctac acgaaacgag ggaaaaacca aagagttccg caatctgttt
    40801 ggccagctag gttatcgtgt ggaaaatctc aatgattatc cagaattgcc agaagtggca
    40861 gaaactggta ctacttttga agaaaatgct cgcttgaaag cagaaacgat ttcacgcctc
    40921 acaggaaaaa tggtattagc agacgattca ggactaaaag ttgatgcctt gggtggttta
    40981 cctggggttt ggtcagctcg tttctcagga ccagatgcca cagatgccaa gaataatgcc
    41041 aaactcttac acgaattagc tatggtgttt gaccaaaaga agcgctcagc tcaatttcat
    41101 acgactttgg tagtggctgc tcccaataaa gatagtttgg ttgtggaagc tgagtggcca
    41161 ggctatattg ctacgcagcc taagggagaa aatggttttg ggtatgaccc tgtctttatc
    41221 gtcggagaga ctgggcgtca tgctgcagaa ttagaggctg accaaaagaa tcagttgtcg
    41281 catagaggtc aagcagttcg aaaattaatg gaggtctttc cagcatggca agcaaaacaa
    41341 tcatagtaat gagtgactct catggtgacc gagatatcgt tcaagccatt aaagacaagt
    41401 atcttggtca agttgatgct attttccata atggggattc tgaattaaac agctcagatc
    41461 ctatttgggc tggtatttat gtcgttggcg gtaattgtga ctatgataca ggttaccctg
    41521 atcgtttagt aactcaatta ggcacagtta cgattgccca gacacatggt cacttgtacc
    41581 atattaactt cacttgggat aaactggact actttgctca agaagtagca gcagatattt
    41641 gtctatatgg acacctacac cgtccagctg cttggcaagt tgggcaaacc ctctttatga
    41701 atcccggatc agtaacacaa cctcgcggag aaattaacga gaaattatat gctcgtgttg
    41761 aactaactga tactcaaatt aaagttgatt actttacaag agatcataaa ctttacccat
    41821 cactgtctaa ggaatttaaa cgatgatcgc aaaagaattt gaaacatttt taatgagtca
    41881 tttagataat tatcttatcc cggaacaaga cttggctatt tttatcgaca cacataatgc
    41941 agaccatgtg atgttactat tggtgagcaa tggtttttct agagttcctg ttatcacacg
    42001 ggagaaaaaa tatgtgggaa ccattagcat ttcagatatt atgatgtacc aatctaaaag
    42061 gcagctgaca gattgggaaa tgagtcaaac agatattggc gagatggtta ataccaaaat
    42121 tgaaaccatt agtattactt ctagcctaac agaaattatg cacaagttaa ttgatttccc
    42181 attcttaccg gttgtagata gagcgaatcg ctttgttggg attattacgc gaaaatctat
    42241 attaaaggct gtcaacagtc ttttacatga ttttacagat gattacacga ttataaaaaa
    42301 atgaagagtt atattgaacc ttttattgct agcaaggctt tatctcaaaa tagtcaaaaa
    42361 gcttatcgat acgatttgca acagttttgt caactggttg gtgaacgtgt caatcaagac
    42421 aaactattac tttatcaaaa tagcatagct aacctaagtt tatctgcaaa aaaacgcaaa
    42481 ttatcaacag ctaatcaatt cttatattac ttgtatcaaa taaagtattt aaatagctat
    42541 tttcgattaa cagataccat gaaagtgatg cggactgaga agcagcaagc tgctattatt
    42601 aatactgata ttttctatca aaaaacccct tttgtgtggg ggcaattaat cagcttatta
    42661 atattggagc tgggtttaac tccgagtgaa gtagctggta ttgaagtagc taacttggat
    42721 ttaaattttc aaatgttgac gctaaagact aaaaaaggtg tgcgtgtatt acctttgtcg
    42781 caaatactaa tccctttttt agaacaacaa ctcgttggca aagaagtcta tctttttgaa
    42841 catcgaggca tccctttttc aagacaatgg ttttttaatc acctaaaaac ctttgttcga
    42901 agtattggtt atgaaggatt aactgctcaa aaattacgag agcaatttat tttgaaagaa
    42961 aaactagctg gtaaatcgat aatagaactt agcgatattc ttgggctgaa aagccctgtg
    43021 accttagaaa aatactacaa atcataatgg atataaaact taaagatttt gaaggtcctc
    43081 ttgatttact cttgcacttg gtatcacagt acaaagttga catctacgag gttcctattg
    43141 ttgaggttat tgagcagtac cttaattata ttgaaacctt acaggtaatg aaacttgaag
    43201 tggctggtga ctacatgctg atggcaagtc agctcatgtt aatcaaaagt agaaggctat
    43261 taccaaaggt ggtagaacac atcgaagaag aagatttaga acaagatctg ttagaaaaga
    43321 tcgaagaata tagtcgcttt aaagcagtta gtcaagcgtt agcgaagcaa catgaccaaa
    43381 gggcaaaatg gtattcaaaa cctaaacaag aattaatttt tgaagatgct atcttacaag
    43441 aagataaaac ggtgatggat ctatttctag ctttttcaaa cataatggca gctaaaagag
    43501 cagttttaaa aaccaaccat acagtcatcg agcgtgatga ttataagatt gaagacatga
    43561 tggcttctat taaacagcga ctggaaaaag aaaacgttat tagcttatca gcgatttttg
    43621 aggaatgcca aacattaaat gaagttatca gtatattttt agctagtcta gaattgatta
    43681 agcttcacgt ggtatttgta gagcagctct ctaattttgg ggctatcata ctacgaaagg
    43741 agaagaaatg acgtatttgt cacagataga agcgctgcta tttgttgcag gtgaagaagg
    43801 gttaagtttg cgacatctag cgtctatgtt atcattaacg ccaacagctc ttcaacagca
    43861 attagaaaaa ctctctcaaa agtatgaaaa agatcaacat tctagtcttt gcttgataga
    43921 aacagctaat acctacaggc tagtaactaa agaaggtttt gcaggactct tgcgtgctta
    43981 tgccaaaaca ccaatgaacc aaagtttatc tcgtgcgagt ttagaggtct tgtctattgt
    44041 tgcatacaaa caacctatta cacgaataga aattgatgac attcgagggg taaactccag
    44101 tggagctttg agtaaattat tggcatttga tctcattaga gaagctggca aaaaagatgt
    44161 ggttgggcgt cctcatttgt atgcgacaac agattatttt ctggactata tgggaattaa
    44221 tcatttagac gaattgattg aagtatctgc cgttgaacca gcagatgaag agattgctct
    44281 ttttaggaca caagactgag ttttgcttgt catcaaatag caaatggcgt ttacaaaagg
    44341 atttgtttta aggcgtttta gttgaaaaaa agccttaaac tagggacaac aaaaagttgc
    44401 tcaaaagaaa gaagaatata atgcgaatta acaaatacat tgcccatgcg ggtattgcca
    44461 gtcgtcgtaa ggctgaagaa ttgattaagc aaggcttagt aaccttaaat ggtcaggtta
    44521 ttacggattt agcaaccact gtaaaatcgg gagacgtggt tgaaatagaa ggaagtccta
    44581 tttacaacga ggaaaaggtt tactatttgc ttaataaacc tcgtggcgct atctcaagtg
    44641 tgtcagatga caaaggccgt aaaacggtac tggatttact acctcaggtt aaagaacgca
    44701 tataccctgt tggacgattg gattgggaca catcaggggt ccttatttta acgaatgatg
    44761 gtgattttac agatactatg attcatccta gaaatgaaat agacaaggtt tatctggcgc
    44821 gtgtcaaagg tattgcaacg aaagaaaatc ttcgtccgct aactcgagga attgttattg
    44881 atggtaaaaa gaccaaacca gctcgctaca atattgttcg tgtagaagct gataagaatc
    44941 gatcgattgt agaattgact atccatgaag ggcgaaacca tcaggttaaa aaaatgtttg
    45001 agtctgtggg gcttttggtt gataaattat ctcgtacacg ttttgggacc gtcgacttaa
    45061 agggactaag accaggagaa gcaagacgct taaataaaaa agaaataagt caactgcata
    45121 acttagctaa tacgaaaaaa tgatgaaaaa actattaata gtatctgtta aagcttatca
    45181 aaaatacatt tctcctttat ctcctcctag ttgtcgctac aagccaacct gttcagctta
    45241 tatgttaact gctattgaaa aacatggtac taagggaata ctaatgggga tagcaagaat
    45301 attaagatgt cacccttttg ttgctggtgg tgtcgatcct gttccagaag attttagcct
    45361 aatgagaaat aaaaacacgt ctaaaaacgc tgaaaaggca tgactttatc aaaaaatggc
    45421 ttgacattga tagctgaagt gttataatgg aaaacaagca ttcgttggtt taaatcaaac
    45481 ctgttatgat ttaagttagc gagtcaccat caaccacatt gtttgctgag catgactccg
    45541 agcagtgtgg ttttttaaat taaaaagagt aaatgagatt atgacgacaa aagaacttat
    45601 caacaaaaac gacaaagtaa aaaaggctcg caatcatatt gtcctgtttc aaccccaaat
    45661 tccacaaaat actggtaata ttgctagaac atgtgctgca actaatgcac ctttacatat
    45721 tattaaaccc atgggatttc ctattgatga ccgcaaaatg aagcgtgccg gcttagatta
    45781 ctgggacaag ttagaactgc atttttatga tcatttagaa cagtttatca atcaatgtca
    45841 cggacagctt cacctgatta gcaagtttgc agttaataat tattctcaag ctacttatgc
    45901 tgatggcgat tcccattatt tcttgtttgg acgagaagat acaggcctgc cagaagattt
    45961 tatgcgagaa catgctgaaa aagcacttcg tattccgatg aatgatgagc atgtacggag
    46021 tttaaatgtc tcaaatacgg tttgtatggt gatttatgaa gcccttagac aacagggctt
    46081 tcaagggtta gagttaaagc atacttacga acacgataaa ctaaaataat ggacttttta
    46141 aaagcgtcag tttttggcaa catgcgttgt cagtagctga cgcttttaaa aatttagtca
    46201 aagctattgc tatctaggtt taaatctgct atgctagaag tgtcttcagg gcagggtgtg
    46261 attcccgacc ggcggtgact aagtaactag aagtccgcga gcgcaagctg atgtggtgta
    46321 actccacaac cgacagtata gtctggatga gagaagaccg ggctttttgt gtaggcttat
    46381 tttagctaca caataacgac ggaacttctt tcaatttgaa aaaattggag gaatttttta
    46441 atgtcaaaaa cacataaaat gattatgatt ggtatacttt ctgcgatatc atttctattg
    46501 atgctagtta gctttgccat tattccaggc gcagcttttt taaaaattga atttagtatt
    46561 attcctgttt tatttggttt aatgattatg gacttaaaga gtgcttactt gattttgtta
    46621 ttgaggtcct tattgaaact ctttttgaac aatcgtggag ttaatgattt tattggtctc
    46681 ccaatgaata ttatcgctat cgctttattt gtgacggctt ttgccttagt ttggaaccgt
    46741 caaaaaacgc ttagtcaata tgtatttgct agcttactag gcacagggtt attaacgttt
    46801 ggcatggttg ttctcaatta tacttttgcc attcctttat atgctatatt tgcaaatatt
    46861 gatatcagag cttatattgg tgttactaag tatatgatga ctatggttat tccgtttaat
    46921 cttgttgaag ggttgatatt tgcaattacc ttttattttg tgtatattgc aagtaaacca
    46981 attttagaaa gatacttaca ctaatatgat gacaaacaaa caaactcact ttttaatagc
    47041 ttcttttgca ttgctaatct ttgttataat aggctatacg gtcaaatttt ttcctgaacg
    47101 tttggcactt ctagataata ctattcaagc agagattaga ggcaaccttc ctatagtgct
    47161 gacgcaattc tttaggggtg ttactgtatt tggaaatgtc atgacacaag ttttgttagt
    47221 tattgtgtcg gtcctagttt tattctttat gaagtggaaa attgaagcct tgtttatctt
    47281 atcaaatggt gccattgcag catttttgat tacgactctc aagctctttt accaaagacc
    47341 aagacctgct attgagcatt tggtttatgc tggtggctat tcgtttccca gtggccatgc
    47401 gatgggtagc atgctgattt ttggtagcct attgattatt tgttatcaaa ggctacattc
    47461 aaaactatta caatttgtga ctagcatgat ctttataata ctaattttag taattgggtt
    47521 atctcgtatt tatctagggg tacactaccc aagtgatatt ttagcaggct ttgtattagg
    47581 atttgggatt ttgcagttta tttatccttt ttataagcaa aaacgatttg aatggcgatt
    47641 tcttttgaaa caagactaat ttttcttgag aagacatagg gcttatttaa atcatttaga
    47701 ataacattgg caagcatcac cccttgattg ccagtgttat tttagtttta gttagatgat
    47761 gtgagctgat gattagtaaa tacgtttaga taaaaaacga ttaaagtgct atgtaacgtc
    47821 agaaaagacg tgatttttgt tgatctgtaa tcattaagta agctgatgta gaagtagtga
    47881 attctaatga ctgagctatc ttttgcatag atgactatct tgctagtaat gatttgtgct
    47941 acaatagaaa catgaaaaaa agatatcaga cattaaacga gcattaccgt caactatttg
    48001 gcgcaaaaat gtttaaagtt ccgattgatg ccggctttga ttgtcccaat cgtgatggaa
    48061 cggtagctca tggaggatgt actttttgca cagtatcagg ttctggagat gctattgtag
    48121 caccagatgc tccaattaaa gagcaatttt ataaagaaat tgattttatg caccgtaaat
    48181 ggcctgatgt caatcgctat ttggtttatt ttcaaaactt taccaatact catgatacag
    48241 ttgatgtgat tcgcgatcgt tacgaacaag ctattaacga acctggagtt gttggcatta
    48301 atattggcac acggcctgac tgtctaccag atgataccat tgcttactta gcagaattat
    48361 cagaacgcat gcatgtgaca gtggagctag gcttacagac aacttatgaa gaaacttcta
    48421 ggctaattaa cagagcacat tcttatgatt tgtataaaga aacggtgagg cgactaaggc
    48481 attaccccaa cattaatatt gtctcgcact tgattaatgg attgccaaaa gaaactcatg
    48541 acatgatgct tgaaaatgtg agacgctgtg taacagacaa tgacattcaa ggaattaaat
    48601 tgcatttgct gcatttgatg accaatacta gaatgcaaag agattatcat gaaggacgct
    48661 taaagttgtt gagtcaaaag gactatgttt cgattatttg tgaccagcta gagattatcc
    48721 ctaagcatat tgtgattcac cgtattacag gagatgcccc acgcgatatg ttgattgggc
    48781 ccatgtggag tctaaataag tgggaagtat tgaatgccat tgataaagaa atggaaagac
    48841 gaggaagctt tcagggctgt aaagttgact aatttgtctc attttgacgg atttggatag
    48901 gagaaaagtg atgctaaaac gccccattca tctctcgcat gattttttag cggaggttgt
    48961 ggataagtct agtgtggttg ttgatgccac gatgggtaat ggaaatgata ctgccttttt
    49021 ggcacaatta gctaaaaagg tttatgcttt tgatgtgcaa gaacaagcta ttagaaaaac
    49081 aagtgagcgg ttagcgcagc taggattatt gaacgctgag ctgattttag cgggtcatga
    49141 agcggttgat cagtatgtga cagagccggt gcgcgcagcg atttttaacc ttggttattt
    49201 gcccagcgca gataaatcta ttattacctt accaaatacc acactccaag ctttatcaaa
    49261 actactaacg ttattaatgg taggtggacg tattgctatt atggtctatt atgggcatga
    49321 tggaggcagt ttggaaaaag atgctttatt agattttgtc aagcaattag accaaagaaa
    49381 ggtttctgca atgctttatc agcctcttaa tcaggtgaat accccacctt ttttaatcat
    49441 gttggagaaa ttagcagacg tttagccctt atccctgtgt caagtctact agaagttctg
    49501 cgattatttc ggtggaaaaa gaagaaatcc cataggcttt ggctataaat gtgatataat
    49561 gaagtcacta tattattttt ttaggagtta cattaacatg gaagaccctg tgagtcagcc
    49621 cttagtgatt caatttttat tgttagttgt tttaaccttg ttaaatgctt ttttttcagc
    49681 cagtgaaatg gccttagttt ctctcaatcg ttctcgggtg gaacaaaaag cagcagacgg
    49741 tgataaaaaa tacgctcgtt tgttgcgggt tttagaggaa cctaatcatt ttttatcaac
    49801 gattcaagtt gggattacct ttattagttt actatcagga gcaagtttat cagcttcttt
    49861 gggtaaggtg atctcaggtt ggctaggtaa ttcagcgact gcaaggacag ctggtactat
    49921 catctccttg gttttcttga cttatgtctc tattgtttta ggagaattgt atccaaaacg
    49981 gattgccatg aacctcaaag acaagttggc gattgtttca gcccctatta tcattgggtt
    50041 agggagactg gttagtccct ttgtatggct cttatcagct tctactaatt tactgagccg
    50101 acttacccct atgacctttg atgatgcaga tgagcaaatg acacgtgatg aaatcgagta
    50161 tatgttatca aaaagtgagg caacccttga tgctgaagaa attgagatgt tgcaaggagt
    50221 tttctcactt gatgaaatga tggcgcgtga agtcatggtc ccaaggaccg atgctttcat
    50281 gattgacatt aacgatgatc cgcttgaaaa tattcaggaa atcttaaaac aaagtttttc
    50341 acgcattcct gtttatgatg tggataaaga taaaattatc ggtctcatcc acactaagcg
    50401 tctcttggag tcaggtttcc gccagggatt tgatcagatt aacatgcgaa aaatgttaca
    50461 agaacctctt tttgttcccg aaaccatttt tgtagatgat ctcttacgcc agctgcgcaa
    50521 tacccaaaat cagatggcta ttttgctaga tgaatatggt ggtgtggcag gacttgtgac
    50581 tttggaagac ttgcttgaag aaatcgtcgg tgaaatcgat gatgaaaccg ataaagcaga
    50641 acaatttgtt catgagattg gagacaatac ctatattgtt gttggtacta tgactttaaa
    50701 tgagtttaat gactattttg ataccgaact agaatcagat gatgtagata ccattgctgg
    50761 tttttatttg acaggtatcg gaaccattcc aagccaggag caaaaagaag cctacgaaat
    50821 agataacaaa gacaaacatt tagttctaat caacgataaa gtcaaagatg gccgtattac
    50881 gaaattaaaa ttaatcctgt ctaatataga acagattatt gaggaagact aggctccatg
    50941 cctagtcttt ttgatgaaaa gtgttataat gaaaatgtaa aaacgtttac aagtaatgaa
    51001 ggagatgcaa tgactgagaa agattatgaa caagtaacag ggatggtgca ttcgacagaa
    51061 agttttggtt ctgtagatgg tccaggcatt cgttttatca ttttcttgca aggctgtaaa
    51121 ttacgttgcc aatattgcca taatcctgat acttgggaga tggaaaccaa caattcaaaa
    51181 atcagaacag tcaatgatgt cttgaaagaa gcccttcagt acaaacattt ctggggaaaa
    51241 aaaggaggaa ttaccgtatc tggtggtgaa gctatgcttc aaattgattt tatcactgcc
    51301 ttattcatcg aagctaaaaa attaggtatc cataccacac tagacacctg tggctttacc
    51361 tatagaccga cacctgaata ccatcaggtt cttgataact tattggcagt gaccgatttg
    51421 attttattgg acttaaaaga aattgatgaa aaacaacata aaattgtcac gcgtcagcct
    51481 aataaaaaca tattgcaatt tgctaggtat ttatccgaca agcagattcc tgtctggatt
    51541 cgacatgtct tggttccagg cttgactgat attgatgatc atttgacacg attgggtgag
    51601 tttgtcaaaa ccttgaaaaa tgtcgataaa tttgaagttt tgccttacca taccatggga
    51661 gaattcaagt ggcgtgagct aggtattcct tatcagttag aaggtgttaa accaccaact
    51721 aaggaacgcg ttcaaaatgc taaaaatctg atgcagaccg aatcttacac agaatatatg
    51781 aatcggattc atcagtcata agagctgtta tagggttgag gtttcctcaa ctttttaaag
    51841 tattataagc agatcttttg taatcttcct ttgattttag ggggtaattt tgctaaaata
    51901 aaatgaataa acaaaatgag gtagaatgat tatgtcaaaa attttagttt ttggtcatca
    51961 aaatcctgat acggatgcta ttgcatcatc ttatgctttt gattacttat cccaaaaagc
    52021 gtttggtttg gatactgaag tcgtagcttt aggaacacct aacgaagaaa cagcttttgc
    52081 ccttgattat tttggtgttg aggcaccacg tgtggtagag tctgctaaag cacaagggtc
    52141 tgaacaagtg attttgacag accacaatga attccaacaa tccattgcag atatccgtga
    52201 ggttgaggta tatggtgtgg ttgatcacca ccgtgtggct aattttgaaa ctgcaaatcc
    52261 tttatacatg cgtgtggaac cagtaggatc agcctcatct attgtttacc gtatgtttaa
    52321 agaaaatggt atcgaggtgc caaaagcgat tgcagggatg ctcttatctg gtttgatttc
    52381 agataccttg ttgttgaaat ctccaacaac tcatgtgtct gatcaccttg tcgctgaaga
    52441 attggcagag ctagcagaag tgaacttgga agactatgga atggctcttt taaaagcagg
    52501 tacaaacctt gcaagcaaat cagaagtaga attgattggt attgatgcca aaacatttga
    52561 attaaatggc aatgctgtgc gcgtggcaca agtgaacact gttgacattg cagaagtctt
    52621 agaacgtcaa gaagctattg aagcagccat taaagatgcc atggctgcag aaggttattc
    52681 agactttgtt ttgatgatca cggatattgt taactcaaac tctgaaattc tagctattgg
    52741 agcaaacatg gacaaggttg aagcagcctt taacttcacc cttgacaaca atcatgcctt
    52801 cttagcaggt gccgtttctc gtaaaaaaca agtggttcca caattgacag aaagttttgg
    52861 agcttaatga aaagacgctt taaaaggact tggttttttt gaccaagtcc ttttttcact
    52921 cttctatgct ataatagaag gtatgataac aatatttcat tcagataaac tcaccagaca
    52981 acctttcttt caagacctta tcaattatct cgaccagcat gatcacgtta tattacgaga
    53041 gatcaaaaaa gcctttccta atgtgacagg tattgacaag gccatcgaaa gctatgttca
    53101 agctggctat attcgccgtg aaaataagcg ttatggcatc aatcttcctt tggtgagttc
    53161 tgatcagcag ctggccttag acactatgct ttttgtggac acctgttcag ctatgtatga
    53221 aaatatttta gcggttgttt ttgagactca gctaacaaac caaaccaatc acgtgatgat
    53281 caaggaaaag accaacatca cgagaagtca gttgactcta gctaattatt tttaccgtct
    53341 caaaagaggt gagaagccat cagctgagca gatggacttg tatgacctct tgggggatgt
    53401 gaatcaggaa tatgccctta aatatatgac aacttttttg cttaaattca cgcgcaaaga
    53461 ccttgtgatg caaaaacgtc ctgatatatt tgtggaagct ctggttacac ttggttacct
    53521 aaaacaagtg gagcctacaa cataccagct gctaatgacc ttggataaag aaagtttaac
    53581 ctttatagca ccatagaaaa gagctaggaa caaggactgt tcttagcttt ttgagtgctt
    53641 ttattttgtt tttgccatta agtaaagaaa ataaggggct ccgataagcg acactaaaat
    53701 ccctgtctgg atattactgc caacaagata gactcgtccg actgtatctg caacaagaag
    53761 taggatcatt ccgattaaaa tactaatggg tattgttatt ttatgattac tccctaccaa
    53821 gtatgtacta aagtgtccag ctattaagcc gataaaacta atattaccaa ccaaaagaac
    53881 actcaaagca cctaagccag ctgctaagac aagtatcaaa cgacgcttac ggtttaaagg
    53941 gagtcctagc ccaatagcag tattatcagc taatcccata atattaagga aatgggcttg
    54001 actataagtc aatagccaaa aacacaataa taaaggagcg atgacactca gagtaggcca
    54061 gtcgtctcct attaattggc cgctaagcca attgatgacc aaatcgactt tgtagcgatt
    54121 aatatgacca acaagagcaa ccattagact tgaaagtatg gtagtaacag ctacaccagt
    54181 aagaattaac cgtgtaggat caatttgtcc ttgttttgtc aaagatagcc aataaacgct
    54241 aaaggttgtt acaatagcac caagcatggc aaataaaggc aagtaatggc tgatatgagc
    54301 ttgctcaaag aaagaaaagg agaccacaat agccaaagag atacctgctc ctatagtaat
    54361 acctaataca ccagagtcag ctaagggatt tcgtgttaaa cgttgtaata atagccctga
    54421 taaagcaaga gaaccgcctc ctagacaagc agctagaatt cttggcagac gaatgttaat
    54481 aacgatgaaa gatatggcat ggctagattt tcccaaaaac acatggataa ggtccaaaaa
    54541 agatagatga gattctccaa gggacaaagc taatcccata agacttacaa gtagcaggat
    54601 caggctagta tataacctta aaaggtgtcg gtgagatttc aatagcggcc tcctcttctt
    54661 attaaccata aaaagcatgg aaaaccaatt aagctaacca atgccccaag aggggtttca
    54721 taaggcggat tgagattacg acaagcaata tcaacccata ccatgaaact agcgccagaa
    54781 actgcacaaa gcggcaaaag gtatcggtaa tgatgaggtg taaaatgttt cataagatga
    54841 ggaatgacta agccgataaa agaaatgctt ccagcaatgg ctacagctgc tgatgataaa
    54901 ataagaacca aaatcataaa gactgcactg atcaagttgg tcttttgccc aagagctttt
    54961 gcctgagact cacttagact aaggacggtc aggtgataag ataatagctg ggctaaacaa
    55021 agactaagaa taataagagg agcaatatag ccgatcattt gccaattgac cccgacaaga
    55081 cctcctgctt gccagccgat aacagcattt gtcagatgat agtaattggt aataccttga
    55141 cctaatgctg atagcagtat ggaaaccata gctcctgcta agacaaggcg gagctgatgg
    55201 tagcctttgc cagattgata agaaaggcca aagactaagg ttgctgccag gctagaccct
    55261 aacaacgaaa gcagaataat gagggaatag tgcaagtgag gtacaaacgc ataagccagt
    55321 accaaggcta gtcctgctcc agcattaatg cctaaaaggc caggctcagc gataggatta
    55381 cgtgtgattg cttgcatgat agttccagaa acagctaacg cagagccagt taaggtagca
    55441 ccaaaaagtc tcggtaatcg tatagctagt aaaacattgg ctttatggcc gttttgcttt
    55501 ccaaataaaa tagagttaag atcctgatgt gataaagcaa cggctccaaa gcgcagatga
    55561 cagtaaatag caacacataa gctaaaacta agtagcacaa agacaagcca aaagatatgt
    55621 gacttagtga ttatctgcgt tttttttaag caaaaacgct cgagacacaa aaagggatgc
    55681 ttagttttca cttgataaga ttgcctctcg taaagactct aattgatatt ctaaagaaag
    55741 aggatcagta aagtaaaaga cattggcatt gactttgatc acatggtgtt ttttcacagc
    55801 tggaatggat tgccatagct tgctttcata tagagcagaa ccagtcttat catcttctgc
    55861 agcaacgacg acataatcac caatatagtc tggcaagact tcctgcgaca atgacaggta
    55921 accttgttta aaaacttcag tcttcacttt ttcaggagca tcataatgga aagcttgatg
    55981 gataacctct ccgccacgtc cccagtcttt accaaaaagg taaacgtctt tttcataaag
    56041 ccccataata gtaaaggttg ctttgtcacc tgtaacggcc ttgacttctt tttcataagc
    56101 tgctgtttta gttttccaat cttttaacca tttcttggct ttgccttctt tgttaaagat
    56161 gcggccgaag tcagataaca cttgtaaata atcacgtttg cggtattcaa tcgaaataac
    56221 aggcgcaatt tctgccaatt gtttaatatt ttcttctgta gagccaacaa caatgaggtc
    56281 aggcttaagc gttgtaatgg cttctaaatc agttgcagta acttgctttg ctttttttac
    56341 agtctttgct aagatggggt ttttcttgtc ataagaagta accccgacta gattcatatc
    56401 taattttttg aggtaaccag tgtaagttga agccagactg actactcgct taggctgttt
    56461 aggaatatct ccgtaataag tcacaccagc aatttgaggc ataggcgata aactttttga
    56521 ggcggtgtta gaatgattag ttgcttgatt accacaggcg attaaggtaa tagttgtcaa
    56581 acagagtgtt aatagtagag ttaatttttt catgtatgct aattctccta gaataaagtt
    56641 attgaagctg ataagtcagc actataggac agttgtggat aggatcatca accagtaccg
    56701 gtttgatttg gaagatgtct tgaatgatag gtgaagtcat aacatctgct atagtaccag
    56761 tataatggat cttgccatgt ttcatagcaa tcagatgatc cgaatagcgg gctgaaagat
    56821 tgaggtcgtg aagaaccata acaatagtct tgccggcatc cttatttagg gatttaacga
    56881 gctctaggat ttctagttga tgatttaaat ctaaataagt agttggctca tctaaaaaaa
    56941 tagtatcagt gccttgggct aatgccattg caagccaaac cctttgacgt tgccccccag
    57001 aaagagcatc aacaggttga tcagcatagg ccatgacatt ggtggcttgc atagcccaat
    57061 gaatggcttt tttgtcagct ggactaagat ttccaaagta agattgatgg ggaaaacgtc
    57121 cgtaagaaac caattcgtaa acagttatgc cgttagttgc ttcttgaact tgaggtaaaa
    57181 gagctagttt tttagcaacc tctttagttt ctaatgtggc aatgttttgc ccatttaaat
    57241 acacaactcc ctgttttggt ggtaataatc ttgtcagtgc ttttaataaa ctagacttcc
    57301 cacagccatt ggcgccaata atggtcgtaa ttttaccttc aggaatataa aacgataatt
    57361 tatcgatgat ggtacgctgt tcataggcga ttgtgaggtc ttcagcacta attgttgtca
    57421 tatggttgcc tcctttctaa aaagagtcaa agggttgatg aaagtgcaca ttaaagtatt
    57481 catctgccca ttttaaaata tttgagaagt agcttatttt ctcaaaatct tcactattat
    57541 agcatagaaa aaaggcttaa caaagccttt tttgatgtga tttttaggat gtattaaaaa
    57601 agaaatatta gtttagaatg attaaaaaca atagcgagaa tcattctaaa ctaacgtcaa
    57661 catactctag aggtagtgtt tggcgattgc taaatcacca gcataagcta cttgttgtcc
    57721 tttaacaatt tgataagcat ctgcgccttt cccagcgata atcacagcat cttttgctcc
    57781 ttggcaaaga gacatggctt tttgaatagc ttgctcacgg tcactaataa tctctaccgg
    57841 gcgtgcgata tggctggcaa tttcttttga aatatcttct ggatcctcga aattagggtc
    57901 atcagcagtg agaatgacgg tgaggtttgg atgctgatga atcaccctac caaaatcagc
    57961 tcgtctgctc tcgcctttat ttcctggtgc acctaaaatc aacattaatt tgcctgtctg
    58021 atgttcttcc acaacgctga gtaatttttc taagctgtca ccattatggg cataatcaac
    58081 aaaaacttta gcatgatttg tcatagtgag gacttccata cggcctggga cgcgagtctt
    58141 agcgatgcct ttttgaatat cagctaggct agcacccaaa cgaaggcagg caagtccagc
    58201 tgccatagca ttttcttggt taaaatggcc aattaattga atgtcataat ggccagctaa
    58261 ttgtccttta gcttcaaagg agaaagcttg gctagtggtg atctggttgt cagacaaggg
    58321 accataaaac acatgctctt gatccgctac ctgatcagct agaaatgaaa aatgatccat
    58381 cccgctattg atcacaacag ctctgctatt ctccattaaa agacgcttat gatagaaata
    58441 atcttcaaac gttggatgct cgattgggcc aatatgatca ggactaatat ttaggaaaac
    58501 cccaacatcg aacgtaagcc catagacacg gtcaacgagg taagcctgac tagaaacttc
    58561 cataatcaag tgggtcatgc cattagtcac acactcagcc atcatagcaa aaagatccaa
    58621 gctttcagga gttgtaagtt gtgatttgaa aaaggtcttg ccatctaagg tggtattcat
    58681 ggtagaaaac atggcaggtt tataggattc tttcaacatg tggtaggcaa aataagcagc
    58741 cgtcgtcttt cccttagtac ctgtaaaagc tagtagtttg agcttttctt gagggttgcc
    58801 atagaaagcc atggcaatta gactcatagc ttttttgata tcagtgacca aaacaacggg
    58861 aataccaagc tcgtaatcta cctctgaaat atagagttgt aatccgttag tgattgcttc
    58921 tttaaggtag tcagctttga aagttgctcc tttagcaaaa aaaagggtct tgccatctac
    58981 ttgacggcta tcgtaactca agcgctcaaa acttaagcct tgataatggt agtggtatcc
    59041 gtcggcatca agaacctcac gaaaattatg gtcttttttt aaaatgtcta ataattgttc
    59101 aatggttatc atacccttat tttatcctta aagttcttgt tttacaagtc acaagcaaaa
    59161 gtttataata aaactaatag aaactaggaa agaatagata tgtcgacaga aaaaaaacaa
    59221 ctgacacaag aagaattaat ggttcaggga gcagcctggt ccacagctgg taatttcatt
    59281 agccgacttt tgggagtgtt atacattatt ccctggtata tttggatggg gcaatacgcg
    59341 attcaagcca acgctctttt caatatgggg tataatgttt atgcttattt tttattgatt
    59401 tcaaccacag gactcaatgt tgcgattgct aagcaggttg ccaagtacaa ttccatggga
    59461 caaactgagc atagctatca attaatccga agtaccctaa aactcatgct tggtctgggc
    59521 cttatttttt cagtcattat gtatctgggc tctcctttat ttgcgagctt atctggtggt
    59581 gatgacacac ttgttcccat tatgcacagc ctttctttag cagtttttat ttttcctgta
    59641 atgagtgtca ttcgaggtat ctttcaaggc cacaataata tcaagcctta tgcgattagt
    59701 cagattgctg agcaactcat tcgggttatc tggatgcttt tgaccacctt ccttatcatg
    59761 aaattaggtt ctggtgatta cgcttcagca gtgactcagt caacttttgc agcctttatc
    59821 gggatggtgg ctagtatggg tgttctgggg tactatcttt ggaaacaggg acttctagca
    59881 gctattttta gtaagccaga tcatactgtt tccattgata tcaagggctt gttgcttgaa
    59941 acattaaaag agtctattcc gtttatcgta acaggaagtg ccattcaagc ctttcaattg
    60001 attgatcaat ggacttttgt caatactatg actcttttta cagattatag ccgttctcaa
    60061 ttgcttgttt tatttggtta ctttaacgca aacccagcca aaattacaat ggttttaatt
    60121 gcagtagcag catctattgg tggtgtaggc attgccttat taactgaaaa ttatgtcaaa
    60181 aaagacatga aagcagctgc tcgcttaatc attaacaaca ttgaaatgtt agtgatgttt
    60241 ttgttacccg ctcttactgg ggcaattatt ttagcaagac ctctatattc tgttttttac
    60301 ggagctagcg aggatcgtgc cattcacctc tttgtggcgg tcctcttcca aaccttgttg
    60361 atggcgcttt acaccctttt ttcaccgatg cttcaagctc tttttgaaaa tcgaaaagcg
    60421 atttactact ttgcctatgg tatcttgatt aagttagttt tacagatacc gcttatttat
    60481 ttgctacatg cttatggtcc tttactagcg acgacgattg ctttagtggt gccgatttat
    60541 ttgatgtatc gacgcctata tcaggttact cattttaacc gcaaactgtt gcaaaaacgt
    60601 ttattattaa ccttgattga aaccttatta atgggactgg tcgtgtttgt ggccaactgg
    60661 ctattgggct atgcctttaa accgacaggc cgcttgacca gccttcttta tctcctcatt
    60721 attggtggcg tgggaatgac ggtttacacg gcactcacct tgctgacgca tcaactggat
    60781 aaattaattg gtagcaaagc tagtcgcctt cgtcagaaat taggctggca ttaatataat
    60841 gacaccaaga acgatttcgt gagtgtttat cgaaatcgtt tttttcttaa tgatctcgct
    60901 tagtaaaggt agctgataaa aaatcaggat ttcccaagca aactactgat atttttggta
    60961 taatgataaa agtgtaaaaa aatagaagga agtatatcaa catgggaaaa tgtcaagtta
    61021 tttcgcatcc gcttatccaa cacaaacttt caatcttacg tcgtcaaacc acatcaacta
    61081 aagattttcg tgagttggtt aatgaaattg cgatgctgat gggatatgaa gtgtcacgcg
    61141 accttccctt agaagatgtc gacatccaaa cgccagtctc aaaaacggtc caaaaacagt
    61201 tagctggtaa aaaattagct attgttccga ttcttcgtgc tggtattggg atggttgatg
    61261 gcttgttaag tttggtacca gctgcaaaag ttggccatat cggcatgtac cgtaatgaag
    61321 aaacccttga acctgttgaa tacctcgtta aactaccaga agatattaac caacgacaaa
    61381 ttttccttgt tgatccaatg ttggcaacag gtggttcggc tatcttagca gtggattcgt
    61441 tgaaaaaacg tggcgcagca aatattaagt ttgtctgttt agttgcagca ccagaagggg
    61501 tgaaaaaact tcaagaagct catccagata ttgatatctt cacagcagca cttgatgatc
    61561 atttaaatga acatggctat atcgtgccag gcttgggcga tgctggtgat cgtttatttg
    61621 ggacaaaata aaagagacaa ccatcaaata gtagcctttt taggccaatc gttcttgatt
    61681 ttgttaaaaa aatcagagag atttctcttc tttaaaggaa aagcaagttt atgatttgac
    61741 ctttattgac caaaatatta taataaggac aatcagtaaa aaagagatga cctagtgggt
    61801 tgccgtctct cacaatgacg ctactaaaaa cccttgtaga ttggagaatg tattatgatt
    61861 cctgttgtta ttgaacaaac tagccgtgga gaacgttctt atgacattta ttcacgttta
    61921 ttaaaagacc gtattatcat gttaacaggg cctgtcgaag acaacatggc caactctgtc
    61981 atagcgcagc tcttattcct tgacgcgcaa gacaacacta aagatatcta cctatatgtc
    62041 aacacaccag gtggctctgt ctcagcaggc ttggctattg tcgataccat gaactttatc
    62101 aaggccgatg tgcaaactat tgtcatgggt atggcagctt ctatggggac agtcattgct
    62161 tcatcaggaa caaaaggcaa acgctttatg ttaccaaatg cagagtatat gatccaccag
    62221 ccaatgggtg gcacaggcgg tggcacgcaa caaacggata tggctatcgc ggcagaacat
    62281 ctcttaaaaa cacgtcaccg tttagaaaaa atcttagcgc aaaatgctgg aaaaacgatt
    62341 aaacaaatcc ataaagatgc tgagcgtgat tattggatga gtgctgaaga aaccttggct
    62401 tacggtttca ttgatgaaat catggaaaac aacgaactaa aataaagagg atctctgcaa
    62461 aagtattcta gaaacttcta ggatgctttt tctcttagaa aggaaaataa tgatacagcc
    62521 tactgcatta aaacagcttc aagagttaaa acgtcagttc agatcccttt gcaaccaatt
    62581 atgagatagt ttgaggatga tccttagcag ctgtgtgcaa gaagttatgg cgatttcata
    62641 aaggatgacc tagccagtct ttcttcgtct cttttactta aagtgtggta taatcagatt
    62701 atgctagcca caactaaaaa aggcattgcc attaaaggtg ttgtagatcg gcttatccta
    62761 gatctcataa caatgctgta gtaccgccct taccttgcta ctaaagacgt tgttgaagca
    62821 caaattgact tgcaaaggat cttgactgat aggtacatgt ccggtggaat cgccaaagca
    62881 gcaaaaagac caagaccctt atttggtctc taccaaaata taatagaaaa ggatttagaa
    62941 tgtttcaaaa acaagaacgt attggactcg tcgtttacct gtattataac cgagatgcca
    63001 gaaagttatc aaaatttggt gatttatatt accattccaa gcgctctcgt tacctcatta
    63061 tttatattaa taaaaatgat ttagacacaa aattagaaga aatgagacgt ttgaaatgtg
    63121 ttaaagacat tagaccatca gcttttgatg atattgaccg ccaatttgta ggtaaccttc
    63181 atcgcgacga aacaaacaac catcaaaagg gttaccaacc ccctagttac tgattagcgt
    63241 ttcagattta gttagcttat tcaagtaaga aggttttgac agatgctcac actacttcaa
    63301 gacaatgaga caactagagc attagtgaat aactgagttg actgtcactt ctttaataag
    63361 aacggatagg attggtccta aaatagagca ctgcaa
//
LOCUS       DAUGUF010000007        56705 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUGUF010000007 DAUGUF010000000
VERSION     DAUGUF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56705
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.007"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            73..708
                     /locus_tag="VIB71_000421"
     CDS             73..708
                     /locus_tag="VIB71_000421"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEQ8822181.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGG
                     VAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            726..1601
                     /locus_tag="VIB71_000422"
     CDS             726..1601
                     /locus_tag="VIB71_000422"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEQ8822182.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQKPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHINAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            1620..1860
                     /locus_tag="VIB71_000423"
                     /pseudo
     CDS             1620..1860
                     /locus_tag="VIB71_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
     gene            2265..2588
                     /gene="yabA"
                     /locus_tag="VIB71_000424"
     CDS             2265..2588
                     /gene="yabA"
                     /locus_tag="VIB71_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEQ8822183.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            2593..3456
                     /gene="rsmI"
                     /locus_tag="VIB71_000425"
     CDS             2593..3456
                     /gene="rsmI"
                     /locus_tag="VIB71_000425"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEQ8822184.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSILEILSYL
                     EETPLKGECLLIVAGAQVDSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            3483..3875
                     /locus_tag="VIB71_000426"
     CDS             3483..3875
                     /locus_tag="VIB71_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822185.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(3922..4551)
                     /locus_tag="VIB71_000427"
     CDS             complement(3922..4551)
                     /locus_tag="VIB71_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEQ8822186.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENH
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQNLSQLTGTAIVHGTKII"
     gene            4850..5206
                     /locus_tag="VIB71_000428"
     CDS             4850..5206
                     /locus_tag="VIB71_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEQ8822187.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEVIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGR
                     VLQVGYRKPYQELDLG"
     gene            complement(5280..6107)
                     /gene="xth"
                     /locus_tag="VIB71_000429"
     CDS             complement(5280..6107)
                     /gene="xth"
                     /locus_tag="VIB71_000429"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEQ8822188.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            6341..7522
                     /gene="lctO"
                     /locus_tag="VIB71_000430"
     CDS             6341..7522
                     /gene="lctO"
                     /locus_tag="VIB71_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEQ8822189.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSTGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            7787..12730
                     /gene="scpC"
                     /locus_tag="VIB71_000431"
     CDS             7787..12730
                     /gene="scpC"
                     /locus_tag="VIB71_000431"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEQ8822190.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMTTTVAADELTTTSEPT
                     ITNHTQQQAQHLTNTELSSAESKPQDTSQITLKTNREKEQPQGLVSEPTTTELADTDA
                     APMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFD
                     EDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKY
                     ESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIED
                     AVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDP
                     LATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVD
                     FKNIKDSLGYDKSHQFAYVKESTDAGYNAQNVKGKIALIERDPNKTYDEMIALAKKHG
                     ALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVS
                     KAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIA
                     GASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNI
                     DGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQ
                     KGRFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRF
                     RDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGK
                     HFTGLVTLGSETNVSTKTISDNGLHTLGTFKNVDGKFILEKNAQGNPVLAISPNGDNN
                     QDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTL
                     LGTAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDP
                     ETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQA
                     DGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKE
                     TLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKG
                     LKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQ
                     YVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVRE
                     EVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVED
                     RAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYY
                     NNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATSQ
                     ITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRI
                     EGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSAT
                     AKALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            13502..14209
                     /locus_tag="VIB71_000432"
     CDS             13502..14209
                     /locus_tag="VIB71_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEQ8822191.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWAIKKGLHWYLLSSFIL
                     TGIAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            14449..16449
                     /gene="metG"
                     /locus_tag="VIB71_000433"
     CDS             14449..16449
                     /gene="metG"
                     /locus_tag="VIB71_000433"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEQ8822192.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDDRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDSLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKFYPNEQELVGKKLQIVA
                     NLKPRKMMKKYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            16943..17956
                     /gene="nrdF"
                     /locus_tag="VIB71_000434"
     CDS             16943..17956
                     /gene="nrdF"
                     /locus_tag="VIB71_000434"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8822193.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            17960..18448
                     /gene="nrdI"
                     /locus_tag="VIB71_000435"
     CDS             17960..18448
                     /gene="nrdI"
                     /locus_tag="VIB71_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8822194.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            18415..20595
                     /gene="nrdE"
                     /locus_tag="VIB71_000436"
     CDS             18415..20595
                     /gene="nrdE"
                     /locus_tag="VIB71_000436"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8822195.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRVYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYHAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECHSCMI"
     gene            complement(20800..21552)
                     /locus_tag="VIB71_000437"
     CDS             complement(20800..21552)
                     /locus_tag="VIB71_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEQ8822196.1"
                     /translation="MLKKRYQLAMILLLSCFSLVWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLLYPRAEQEAMAAYTCQQAALINTSLDKTKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDHKKLHIEAYFKGSL"
     gene            22012..22446
                     /locus_tag="VIB71_000438"
     CDS             22012..22446
                     /locus_tag="VIB71_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822197.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMGRPVNAEVTYTGERSTSVN
                     GPGEDSSSEKTEQTSDSDKRDRNRGYEEGYKRGQESDNRVLDRGTIEVPYNVIDGVEY
                     KDGYEQGFAAGWYDGHPITALLDIAWSYLTYAFDVLFGGTNS"
     gene            22889..23302
                     /locus_tag="VIB71_000439"
     CDS             22889..23302
                     /locus_tag="VIB71_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822198.1"
                     /translation="MTKAIKLVILSLILFTTVFLSVRQASADLMMDGVTYSESTDSNT
                     FLSNSGEVDNIWEKDRDFGKQRGLEAGKNGLGPTINRGDIPVPEKVKHKDKYQDGYQE
                     GYIQAWHQEHPFQGVIFAVFDVFSLIWGVISELFT"
     gene            23543..23794
                     /locus_tag="VIB71_000440"
     CDS             23543..23794
                     /locus_tag="VIB71_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822199.1"
                     /translation="MPEKKVLPVLSMVVSLVSLFDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLILAALAVAVVAYAYYDPTVIPY"
     gene            complement(23888..24520)
                     /locus_tag="VIB71_000441"
     CDS             complement(23888..24520)
                     /locus_tag="VIB71_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822200.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDEQSSKQKPVKFDLDEPQQKI
                     KDYSGNTITLEDLYVGSKVVKIYIPQGWWVYLYRQCDHNSKERGILASPILEKNMTKT
                     DPYRQYYTGVPYILNLGEDPLKKGEKLTFSFKGEDGFYVGSYIYRDSDTIKKEKEAEE
                     ALQKKEEEKQQKQLEESMLKQIREEDHKPWHQRLSESIQDQWWNFKGLFQ"
     gene            complement(25032..26000)
                     /locus_tag="VIB71_000442"
     CDS             complement(25032..26000)
                     /locus_tag="VIB71_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3644 domain-containing protein"
                     /protein_id="HEQ8822201.1"
                     /translation="MENLSERLVLKSVEAFIMGLEIYNKPTIKYRIEGFSFFICNAWE
                     LMLKAEMLNRGFSIYYSDNPERTLSLEYVLKKIYSDENTRIRLNLEKIIELRNISTHF
                     ITEDYEIKYAPLFQACVLNLASEMKRFHNKDITESIAHNFLTISASYEPLSNEEIKLK
                     YPSEIAEKFIKQANEVDVLSKEYNSEKFSIDIRQNLYITKKKDEADFVVSISKDAETP
                     VSLVKELKDPSDTHKYSYSNVVTAVQERLKKSAIKLGYEKGFNTYVLNLVIDFYNIKS
                     ETKFSYCHLIGSTQTYTYSQQFVEFIVNEIKKDPQNFVESLKKSNK"
     gene            26612..26848
                     /locus_tag="VIB71_000443"
     CDS             26612..26848
                     /locus_tag="VIB71_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEQ8822202.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            26841..27539
                     /locus_tag="VIB71_000444"
     CDS             26841..27539
                     /locus_tag="VIB71_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEQ8822203.1"
                     /translation="MTKVVLVTGCASGIGCAQARYFLRQGYHVYGVDKSDKPDLNGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWSLK"
     gene            27615..28574
                     /locus_tag="VIB71_000445"
     CDS             27615..28574
                     /locus_tag="VIB71_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ8822204.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKTAKDLA
                     KAYHMPLATSKYEAVLGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVQLSLHGQKPQVINHNKH
                     DHRMYEEFVAFKDMIDQKDFKKVNQALEHSRAVMAVLERAVHS"
     gene            28907..30244
                     /locus_tag="VIB71_000446"
     CDS             28907..30244
                     /locus_tag="VIB71_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8822205.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISILEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            30418..31800
                     /gene="glmU"
                     /locus_tag="VIB71_000447"
     CDS             30418..31800
                     /gene="glmU"
                     /locus_tag="VIB71_000447"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEQ8822206.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKAVTVIGHKSEKVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGQGSIITNSMIESSVLAAGVTVGPYAHLRPG
                     TTLGREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDNALTAAGSTISKTVPADSIVIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            31834..32388
                     /locus_tag="VIB71_000448"
     CDS             31834..32388
                     /locus_tag="VIB71_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8822207.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIESVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            32388..32639
                     /locus_tag="VIB71_000449"
     CDS             32388..32639
                     /locus_tag="VIB71_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822208.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVDFDTKVMTLPEKDEKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            32659..33354
                     /locus_tag="VIB71_000450"
     CDS             32659..33354
                     /locus_tag="VIB71_000450"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEQ8822209.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILAEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQILMTFLENLPV"
     gene            33467..33685
                     /locus_tag="VIB71_000451"
     CDS             33467..33685
                     /locus_tag="VIB71_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822210.1"
                     /translation="MTGPKSHLQYSKDNTKLQLRNILNGYQSDLGRHYSSYYYYNLRT
                     VMGLSSEQEIEEHYEKLKNKLHDMYNHY"
     gene            complement(33782..34429)
                     /locus_tag="VIB71_000452"
     CDS             complement(33782..34429)
                     /locus_tag="VIB71_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEQ8822211.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLSINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            34575..35507
                     /locus_tag="VIB71_000453"
     CDS             34575..35507
                     /locus_tag="VIB71_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEQ8822212.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYGPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            35571..36296
                     /locus_tag="VIB71_000454"
     CDS             35571..36296
                     /locus_tag="VIB71_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822213.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            36297..37151
                     /locus_tag="VIB71_000455"
     CDS             36297..37151
                     /locus_tag="VIB71_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8822214.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(37299..38105)
                     /locus_tag="VIB71_000456"
     CDS             complement(37299..38105)
                     /locus_tag="VIB71_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ8822215.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            38322..40727
                     /locus_tag="VIB71_000457"
     CDS             38322..40727
                     /locus_tag="VIB71_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8822216.1"
                     /translation="MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMFDQDIFLSTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEKIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNIA
                     GYNAKVEDYNRQSEQKQMPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(40797..41150)
                     /locus_tag="VIB71_000458"
     CDS             complement(40797..41150)
                     /locus_tag="VIB71_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEQ8822217.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTPLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            41394..41819
                     /gene="rplK"
                     /locus_tag="VIB71_000459"
     CDS             41394..41819
                     /gene="rplK"
                     /locus_tag="VIB71_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEQ8822218.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            41925..42614
                     /gene="rplA"
                     /locus_tag="VIB71_000460"
     CDS             41925..42614
                     /gene="rplA"
                     /locus_tag="VIB71_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEQ8822219.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            42936..43664
                     /locus_tag="VIB71_000461"
     CDS             42936..43664
                     /locus_tag="VIB71_000461"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEQ8822220.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            43693..44250
                     /gene="frr"
                     /locus_tag="VIB71_000462"
     CDS             43693..44250
                     /gene="frr"
                     /locus_tag="VIB71_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEQ8822221.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            44359..45216
                     /locus_tag="VIB71_000463"
     CDS             44359..45216
                     /locus_tag="VIB71_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ8822222.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYISLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            45289..45798
                     /gene="msrA"
                     /locus_tag="VIB71_000464"
     CDS             45289..45798
                     /gene="msrA"
                     /locus_tag="VIB71_000464"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEQ8822223.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            45795..46010
                     /locus_tag="VIB71_000465"
     CDS             45795..46010
                     /locus_tag="VIB71_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEQ8822224.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            46167..47336
                     /locus_tag="VIB71_000466"
     CDS             46167..47336
                     /locus_tag="VIB71_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8822225.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQSTVPMAPSATPSDVPTTPLASAKPDSFVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDPTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMN
                     AGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYA
                     IDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            47651..49423
                     /locus_tag="VIB71_000467"
     CDS             47651..49423
                     /locus_tag="VIB71_000467"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEQ8822226.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKENETTVWIYGLYSNSKGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLI"
     gene            49582..50634
                     /locus_tag="VIB71_000468"
     CDS             49582..50634
                     /locus_tag="VIB71_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEQ8822227.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEETKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            50680..51255
                     /locus_tag="VIB71_000469"
     CDS             50680..51255
                     /locus_tag="VIB71_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEQ8822228.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEEYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            51414..51911
                     /gene="ybeY"
                     /locus_tag="VIB71_000470"
     CDS             51414..51911
                     /gene="ybeY"
                     /locus_tag="VIB71_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEQ8822229.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            51892..52299
                     /locus_tag="VIB71_000471"
     CDS             51892..52299
                     /locus_tag="VIB71_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEQ8822230.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLSFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            52419..53315
                     /gene="era"
                     /locus_tag="VIB71_000472"
     CDS             52419..53315
                     /gene="era"
                     /locus_tag="VIB71_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEQ8822231.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            53335..53811
                     /locus_tag="VIB71_000473"
     CDS             53335..53811
                     /locus_tag="VIB71_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8822232.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            complement(54495..55105)
                     /locus_tag="VIB71_000474"
                     /pseudo
     CDS             complement(54495..55105)
                     /locus_tag="VIB71_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014572037.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            55424..55651
                     /locus_tag="VIB71_000475"
     CDS             55424..55651
                     /locus_tag="VIB71_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ8822233.1"
                     /translation="MEVKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            55664..55864
                     /locus_tag="VIB71_000476"
     CDS             55664..55864
                     /locus_tag="VIB71_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEQ8822234.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLLHP
                     VLAGGCVVGFTVGGAYLGYTAN"
     gene            56158..56352
                     /locus_tag="VIB71_000477"
     CDS             56158..56352
                     /locus_tag="VIB71_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ8822235.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIP
                     WQGYILCGAAGAATNIIWPH"
BASE COUNT        17462 a        10629 c        12075 g        16539 t
ORIGIN      
        1 tgcaaagata tgccagtgct ttttagctca ttttttgata aaatagaact actaaaaagt
       61 gaaggaaata agatgatcac aggaaaactc ataaccgttg aaggtccaga tggcgcaggg
      121 aaaacgactg ttttagagca actcattcca ctgttaaaac aaaaagtggc tcaggagatc
      181 ttgacaacaa gagagcctgg aggtgttgcc atttcagaat acattagaga acttatttta
      241 gacatcaacc atactactat ggaccctaaa acagaactct tactttatat tgcggctcga
      301 aggcagcatt tggtggaaaa ggtactacca gctcttgaag caggccagtt ggtttttatt
      361 gatcgtttca tcgatagttc agtagcttat caaggtgcag gacgcggttt gatcaaagca
      421 gacattcagt ggctcaacga gttcgcaaca gatggtttag agcctgactt gaccctttat
      481 tttgatgttc cttctgaaat tggtttagca cggattaacg cgaaccaaca aagagaagtc
      541 aatcgtttag atttggaaac aatagagata catcaacgag tacgaaaagg atacctagcc
      601 ttagctaagg agcatccaaa acgtattgtc acaattgatg cgactaaacc attgaaagaa
      661 gttgtctctg tcgctttgga acatgtctta gccttgcttt tagcctagga taagggaggg
      721 taggaatgga tttagcgcaa aaagctccta acgtttatca agcttttcag acgattttaa
      781 agaaagaccg tctgaatcat gcttatcttt tttcgggtga ttttgctaat gaagaaatgg
      841 ctcttttttt agctaaggtc atcttttgtg aacagaaaaa ggatcagaag ccctgcgggc
      901 attgtcgctc ttgtcaattg attgaacaag gagattttgc cgatgtgacg gtattggaac
      961 caacagggca agtgattaaa acggatgtgg tcaaagaaat gatggctaac ttttctcaga
     1021 caggatatga aaacaaacga caagttttta ttatcaaaga ttgtgacaaa atgcatatca
     1081 atgccgctaa tagcttgcta aaatacattg aggagcctca gggagaagct tacatatttt
     1141 tattgaccaa tgatgataac aaagtgcttc cgaccattaa aagtcggaca caggtttttc
     1201 agtttcctaa aaacgaagcc tatctttacc aattggcaca agaaaaggga ttattaaacc
     1261 atcaggctaa gttagtagcc aaacttgcca caaataccag tcatctagaa cgtctgttgc
     1321 aaacgagcaa gcttttagaa ctgataactc aagcagagcg ttttgtatct atttggctga
     1381 aagatcagtt gcaggcatat ttagcgttga accgtctggt acagttagca actgaaaaag
     1441 aagaacaaga tttagttttg acccttttga ccttgctctt ggcaagagag cgtgcgcaaa
     1501 cgcctttgac acaattggag gctgtctatc aggctaggct catgtggcag agcaatgtta
     1561 attttcaaaa cacattagaa tatatggtga tgtcagaata agtgcaattg gaattcgtta
     1621 tggggaaacg aagcttgtca aaagacttgc ccgtagcgac caaagtagcg gcgcataggg
     1681 gcaaaacaag cttttgaaga aaatactgcc tttgcaacag atttgatgaa agaagtatca
     1741 cgattaataa cacaaaatca acttaaaatg acgtttatta atagtgtctt tcccttagat
     1801 cagcatgttg ttctaattcc cttttcagca gaagagcaca tggattttta caactgttaa
     1861 aagatttagc ggccgatttt aggtcaagaa gtgagctgcc ccagattaac agccaagaag
     1921 atttcatttt ctatggaggc tatggaccgt gtggcaggcc actgtgctgc tttcgttttt
     1981 gggaaaattt ctgacagtat ctattaaaat actaaaaaat caagggttat cattgacttt
     2041 gggtaaagca acaagccctt atggccgttt gctttgctgt ctctatgatg aaggtggctt
     2101 ttaccaataa agcaagaaaa aattccctga atatggtacc atagtagaga caagtgatgg
     2161 ccctgcaaca gtagcagccg ttgatatatt tacagatctc attaaggtgc ggttaaaaga
     2221 ccagttgacc ttagtcactt atgctttaga ggaggttaaa gtaggtgaat aaaaaagaat
     2281 tattcgatgc ttttgatgga ttttcccaaa atttaatggt tactttagct gaaattgaag
     2341 ccatgaaaaa acaagtccaa tcactagtag aagaaaacac gattcttcgc ctagaaaata
     2401 caaaactacg ggaacgtttg agtcacctag aacatgaaac ggtagctaaa aatccttcca
     2461 aacaaaggaa ggatcactta gagggaattt atgatgaagg gtttcatatc tgcaattttt
     2521 tctatggaca acgtcgtgaa aatgatgaag aatgtatgtt ttgcagagaa ttattagata
     2581 gaaagtaagg gcatgcaggt tcaaaaaagt tttaaagaca aaaaaacaag cggaaccttg
     2641 tatttggttc caaccccaat tggcaatctg caggacatga cctttagagc agtggcaacg
     2701 ttaaaagagg ttgattttat ttgtgcagaa gacacaagaa acacaggtct tttgctaaaa
     2761 cactttgaca ttgctaccaa gcaaatcagc tttcatgagc acaacgccta tgagaagatt
     2821 cctgatttaa ttgatttatt aatatcagga cggtcactag ctcaggtatc tgatgcagga
     2881 atgccatcga tttctgatcc tgggcatgat ttggtcaagg ctgctattga tagtgatatc
     2941 gcagtcgttg ctttaccagg cgcctcagca gggattacag ctttgattgc tagtggactg
     3001 gctcctcaac cccatgtttt ttatggattt ttacccagaa aagcagggca acaaaaggct
     3061 ttctttgagg acaaacacca ttacccagag acacaaatgt tttatgaatc gccctatcgc
     3121 atcaaagata ccctgaccaa tatgttggct tgttatggtg atcgtcaagt ggtacttgtt
     3181 agagaattaa ccaagctttt tgaggagtac caacgggggt cgattttaga aatcttgtcc
     3241 taccttgagg aaacacccct aaaaggggag tgtctgctga ttgtggctgg agcccaagta
     3301 gacagtgagg ttgagctgac agctgatgtt gacttagtgt ctctagtgca aaaagaaatc
     3361 caagcaggag ccaagccaaa tcaggctatt aaaacaattg ctaaagctta ccaggtaaat
     3421 cgccaagagc tttaccaaca atttcatgac ttataagtca tcgtagatta ggagaaaaac
     3481 aaatgacaga agatcaagca actatcctta ttttaggagt atacggaatc atattggctg
     3541 tattcttatt atcagcctta ttatgcctta tcgctaactg gcgactcttt aaaagagcag
     3601 gttacaaagg atggtatagt ctcattcctt tctatgcagg ttttgtcaaa cacaaaatca
     3661 cttttggaga agataataaa tggttttact ttattggttg ggtcattgct atttattatt
     3721 actatgtgca cttttgctat gtccgtgctt ttggtggatc aaagggtcta gcagtatttg
     3781 gcttgttttt cccaggcatt gcttctttga tagtggcttt tggaaaaact tataccacac
     3841 aagaatgcca ccctgtgcca catcttttaa actaagagaa aaaagaccat caattggatt
     3901 tattgatggt cttttaggtg tttaaatgat tttagtcccg tgaacaatgg ccgttccagt
     3961 gagttgactc aagttttggc aattctcagc agtgacgcct cctccaatca tgatttcaat
     4021 gcgtttattg gcataggtca caagactttt aagctgttcc acattatctg taataggagt
     4081 agcttcaggg gagccatgag ttagcacacg cacaaagcca taatcaatca gttgatcaag
     4141 cgcttggtgc tggtggtcag tcggaatatg gtcaaaagcc atgtggaaaa ccaatggcaa
     4201 gccttgtgta gcaggcagta actgctcgat agcgtcggta tcaaggtgat tttctgtggt
     4261 cagcaagcct aagactagcg catctgagcc agcttcaaca gcttttaaga tatcttcttc
     4321 catagctttt agttcgaggt cgttatagac aaaatcgcca ccgcgaggtc gaatcatggt
     4381 cgctacgcta atctttttat cgtgtaagag ctgacaggct tctttgatga cgccataaga
     4441 tggtgttgtt cccccgacag ctaggttatc acagagttcc acacgactga cttgaccagc
     4501 atcaagggtt ggcagtagtg tgaggttctc agcacaaaat tctttaatca tttttagatc
     4561 tcctttatca ctaatattat agcacgaatg aagctagtca tcaggaaaca tttttgtcaa
     4621 atcatggaca ttatgttata ctcactagta ttaaaagtag gccaaaacag cagcaaatac
     4681 tttgaaaaaa gattgctatg ttctacggca atatcagtct ttaccaacga actctcaaga
     4741 agaaaagaaa gacaaagctt agcatttaaa aaaagccccc ctttttttgt gaaatgatga
     4801 ccaaaaacag gcgcctcacg cctaaaacag ttaccctaaa ggagaacaaa tgattacgat
     4861 ttaccaatac ccaaaatgta gtacctgtca aagagccatg gctgaactaa agcaactggt
     4921 tagtgacttt gaagtcattg acatcaaagc taatccaccc aaagctcagg acctcaaaca
     4981 ttggatggaa acatctggtt ataccatcaa aaatttcttt aataccagtg gtaacagcta
     5041 ccgcgaattg ggacttaaag ataaaataga ccagcttagc cttgataaag ctgctgaact
     5101 cttagccaca gatggtatgc tgattaaacg gcctattctg attaaggacg gtagagtcct
     5161 acaagttggc tatcgcaagc catatcaaga gttggattta ggataatgcg acaaagtctc
     5221 aaaaaaggac aaggcaacat tataacgcct tgtccttttt tgggatctgt ttttagaaat
     5281 tagagatcaa tatctagtaa aattggcgta tggtcttggc gttccccaga agaaatcatt
     5341 tcagaacgct taaccttatc cacaagtcgg tttgaagcta gccaatagtc aattctccaa
     5401 ccggtattat tgattttgct ggttttgcta cgttgtgccc accaggtata aacatgagga
     5461 atatcgccgt gcaagtgacg aaaagtatct gtaaagcctc ttgctaatag gttagtaaag
     5521 ccttgacgtt cttcgtcggt aaaaccaggg gaacgtcgat tgctgcttgg atttgccaaa
     5581 tcaatctctt tgtgggcaac gttgtaatct cccgtagcca aaacaggctt ttgagcatcc
     5641 agttcagtca agtaatcagc gtatttgtgg tcccaaattt gacggtcatc taaacgtcta
     5701 aggccatcac cagcattagg cgtgtaaacc tgtgtgacga aaaagtcttc aaattctagg
     5761 gtaatgatac ggccctcagc atccattgtt gttggggcac caatttctgg aaaagtaatg
     5821 acagggttta gcgtgttttt gtacaggaac atggtgccag catagccttt cctagcaggc
     5881 tcaactgaag aacgccacac atgcaaatag tttggaaagt aactaagtaa ggtctcgata
     5941 tgttttttgg taggcccctt agcagataat ttggtttctt gaatggcaat aatatccgca
     6001 tcttgagcga ctaaagtgtc taaaacagcg cgtgataaaa gcgcacgagg ggactctcct
     6061 gtgagagcag catttaagga atcaatgttc catgaaatca gtttcatttg gtatctcttt
     6121 ctaacagata gtcttgttgt tattgtaaca aaaaacgaaa cgataagcga ctttggacac
     6181 ctagccccca taaaacagtc tagccaaatg aagcatagca gcgtaagaac aagataagga
     6241 ggtgatcagt gagcatatcg tttgacagtt aagagtagga ttactataat agaagcataa
     6301 atgtaagcgc taacaaagta aaaaatatag gagaatgtca atggcacaaa aaacagtcat
     6361 caccgaggaa acaaccgatt ttgttatgga tttcaaaaca agtagcgctg agggaaatgt
     6421 tgattttatt aacgtttttg accttgagaa aatggcacaa caggtcatcc ctaaaggagc
     6481 ctttggttat attgctagtg gtgctggtga tacctttacc ctccatgaaa atattcgctc
     6541 atttaatcat aaattaattg tccctcactc cctcaaaggg gttgaaaatc cgtcaacaga
     6601 gattacgttt gatggtgatc acttaacctc tcctcttatt ttagcacctg tagcggctca
     6661 taagctggcc aatgaacaag gagaagtagc gtctgccaaa ggattgaagg aatttggaag
     6721 tatctacacc actagttcct actcaacaac tgacctgcca gaaatcagtg ctgccttagg
     6781 tgggacaccc cattggtttc aattttatta cagtaaagac gatggcatta atcgtaatat
     6841 tatggatcgt gtcaaagcac aaggttgcaa agctatcgtt ttgacagcag atgcaacagt
     6901 tggaggaaac cgcgaagttg ataggcgaaa cggctttgtt tttccggtcg gtatgccaat
     6961 tgttcaagaa tatttacctg atggtgcagg taaaacaatg gattatgtct ataaatcagc
     7021 taaacaagcg cttacctcaa aagatattga atatatcgca acttactcag gcctgcctgt
     7081 ttatgtcaaa ggaccacagt gtgctgagga taccttgcga gcattggatg caggagcatc
     7141 aggtatctgg gtaaccaatc atggtggccg ccaattagat ggtggtccag ctgcttttga
     7201 ttccttacaa gaagtcgctg aagcagttga tcaaaaagtt cctattgtct ttgactcagg
     7261 tataagacgg ggtcaacata ttttcaaagc tcttgcttca ggtgctgacc ttgttgcctt
     7321 ggggcgtcca gcgatttacg gcttggctat gggaggaagc actggtactc gtcaggtctt
     7381 tgaaaagtta aatgacgagt taaaaatggt catgcaactg gctgggacac agactatcca
     7441 agatgttaaa gcctttaacc ttcgccacaa tccgtatgat tcatcgattc catttgatca
     7501 aaatgcgcta cgcttagatt agaacagaca aaaacctctg ctatcatgtc acaaatagta
     7561 gaggttttac actgcaaaaa gaggtatgaa aattcaataa catagttaca aggctatcat
     7621 ttaccacccc cactaataga ttaaaatgaa agacttctta cattaataga agtttctgtt
     7681 gcttttctca gaaaaatgtg gttaaataat caaatattat taacgaaaaa tgagttaatg
     7741 attaacatta aactggtttt agttaaaaca tttaggaggg tatcaggtgg agaaaaagca
     7801 acgtttttcc cttagaaaat acaaatcagg aacgttttcg gtcttaatag gaagcgtttt
     7861 cttgatgatg acaacaacag tagcagcaga tgagctaacc acaacgagtg aaccaacaat
     7921 cacgaatcac actcaacaac aagcgcaaca tctcaccaat acagagttga gctcagctga
     7981 atcaaaacct caagacacat cacaaatcac tctcaagaca aatcgtgaaa aagagcaacc
     8041 acaaggtcta gtctctgagc caaccacaac tgagctagct gacacagatg cagcaccaat
     8101 ggctaataca ggtcctgatg cgactcaaaa aagcgcttct ttaccgccag tcaatacaga
     8161 tgttcacgat tgggtaaaaa ccaaaggagc ttgggacaag ggatacaaag gacaaggcaa
     8221 ggttgtcgca gttattgaca cagggatcga tccggcccat caaagcatgc gcatcagtga
     8281 tgtatcaact gctaaagtaa aatcaaaaga agacatgcta gcacgccaaa aagccgccgg
     8341 tattaattat gggagttgga taaatgataa agttgttttt gcacataatt atgtggaaaa
     8401 tagcgataat atcaaagaaa atcaattcga ggattttgat gaggactggg aaaactttga
     8461 gtttgatgca gaggcagagc caaaagccat caaaaaacac aagatctatc gtccccaatc
     8521 aacccaggca ccgaaagaaa ctgttatcaa aacagaagaa acagatggtt cacatgatat
     8581 tgactggaca caaacagacg atgacaccaa atacgagtca cacggtatgc atgtgacagg
     8641 tattgtagcc ggtaatagca aagaagccgc tgctactgga gaacgctttt taggaattgc
     8701 accagaggcc caagtcatgt tcatgcgtgt ttttgccaac gacgtcatgg gatcagctga
     8761 atcactcttt atcaaagcta tcgaagatgc cgtggcttta ggagcagatg tgatcaacct
     8821 gagtcttgga accgctaatg gggcacagct tagtggcagc aagcctctaa tggaagcaat
     8881 tgaaaaagct aaaaaagccg gtgtatcagt tgttgtagca gcaggaaatg agcgcgtcta
     8941 tggatctgac catgatgatc cattggcaac aaatccagac tatggtttgg tcggttctcc
     9001 ctcaacaggt cgaacaccaa catcagtggc agctataaac agtaagtggg tgattcaacg
     9061 tctaatgacg gtcaaagaat tagaaaaccg tgccgattta aaccatggta aagccatcta
     9121 ttcagagtct gtcgacttta aaaacataaa agatagccta ggttatgata aatcgcatca
     9181 atttgcttat gtcaaagagt caactgatgc gggttataac gcacaaaacg ttaaaggtaa
     9241 aattgcttta attgaacgtg atcccaataa aacctatgac gaaatgattg ctttggctaa
     9301 gaaacatgga gccctgggag tacttatttt taataacaag cctggtcaat caaaccgctc
     9361 aatgcgccta acagctaatg ggatggggat accatctgct ttcatatcgc acgaatttgg
     9421 taaggccatg tcccaattaa atggcaatgg tacaggaagt ttagagtttg acagtgtggt
     9481 ctcaaaagca ccgagtcaaa aaggcaatga aatgaatcat ttttcaaatt ggggcctaac
     9541 ctctgatggt tatttaaaac ctgacattac tgcaccaggt ggcgatatct actctaccta
     9601 taacgataac cactatggta gccaaacagg aacaagtatg gcctctcctc agattgctgg
     9661 cgccagcctt ttggtcaaac aatacctaga aaagactcag ccaaacttgc caaaagaaaa
     9721 aattgctgat atcgttaaga acctattgat gagcaatgct caaattcatg ttaatccaga
     9781 gacaaaaacg accacctcac cgcgtcagca aggggcagga ttacttaata ttgacggagc
     9841 tgtcactagc ggcctttatg tgacaggaaa agacaactat ggcagtatat cattaggcaa
     9901 catcacagat acgatgacgt ttgatgtgac tgttcacaac ctaagcaata aagccaaaac
     9961 attacgttat gacacagaat tgctaacaga tcatgtagac ccacaaaagg gccgcttcac
    10021 tttgacttct cgctccttaa aaacgtacca aggaggagaa gttacagtcc cagctaatgg
    10081 aaaagtgact gtaagggtta ccatggatgt ctcacagttc acaaaagagc taacaaaaca
    10141 gatgccaaat ggttactatc tagaaggttt tgtccgcttt agagatagtc aagatgacca
    10201 actaaataga gtaaacattc cttttgttgg ttttaaagga caatttgaaa acttagcagt
    10261 tgcagaagag tccatttaca ggttaaaatc tcaaggcaaa actggttttt actttgatga
    10321 atcaggtcca aaagacgata tctatgtcgg taaacacttt acaggacttg tcactcttgg
    10381 ttcagagact aatgtgtcaa ccaaaacgat ttctgacaat ggtctacaca cacttggcac
    10441 ctttaaaaat gtagatggca aatttatctt agaaaaaaat gcccaaggaa accctgtctt
    10501 agccatttct ccaaatggtg ataacaacca agattttgca gccttcaaag gtgttttctt
    10561 gagaaaatat caaggcttaa aagcaagtgt ctaccatgct agtgacaagg aacacaaaaa
    10621 tccactatgg gtcagcccag aaagctttaa aggagataaa aactttaata gtgacattag
    10681 atttgcaaaa tcaacgaccc tgttaggcac agcgttttct ggaaaatcgt taacaggagc
    10741 tgaattacca gatgggtatt atcattatgt ggtgtcttat tacccagatg tggtcggtgc
    10801 caaacgtcaa gaaatgacat ttgacatgat tttagaccga caaaaaccgg tactatcaca
    10861 agcaacattt gatcctgaaa caaaccgatt caaaccagaa cccctaaaag accggggatt
    10921 agctggtgtt cgcaaagaca gtgtctttta tctagaaaga aaagacaaca agccttatac
    10981 agttacgata aacgatagct acaagtatgt ctcagtagaa gacaataaaa catttgtgga
    11041 gcgacaagct gatggcagct ttatcttgcc gcttgataaa gcaaaattag gggatttcta
    11101 ttacatggtc gaggattttg cagggaacgt ggccatcgct aagttaggag atcacctacc
    11161 acaaacatta ggtaaaacac caattaaact taagcttaca gacggtaatt atcagaccaa
    11221 agaaacgctt aaagataacc ttgaaatgac acagtctgac acaggtctag tcacaaatca
    11281 agcccagcta gcagtggtgc accgcaatca gccgcaaagc cagctaacaa agatgaatca
    11341 ggatttcttt atctcaccaa acgaagatgg gaataaagac ttcgtggcct ttaaaggctt
    11401 gaaaaataac gtgtataatg acttaacggt taatgtatac gctaaagatg accaccaaaa
    11461 acaaacccct atctggtcta gtcaagcagg cgctagtgca tcagctattg aaagtacagc
    11521 ctggtatggc ataacagctc gaggaagcaa ggtgatgcca ggtgattatc agtatgttgt
    11581 gacctatcgt gacgaacatg gtaaagaaca tcaaaagcag tacaccatat ctgtgaatga
    11641 caaaaaacca atgatcactc agggacgttt tgataccatt aatggcgttg accactttac
    11701 tcctgacaag acaaaagccc ttggctcatc aggcattgtc cgcgaagaag tcttttactt
    11761 ggccaagaaa aatggccgta aatttgatgt gacagaaggt aaagatggta tcacagttag
    11821 tgacaataag gtgtatatcc ctaaaaatcc agatggttct tacaccattt caaaaagaga
    11881 tggtgtcaca ctgtcagatt attactacct tgtcgaagat agagctggta atgtgtcttt
    11941 tgctaccttg cgtgacctaa aagcggtcgg aaaagacaaa gcagtagtca actttggatt
    12001 agacttaccg gtccctgaag acaaacaaat agtgaacttt acttaccttg tgcgggatgc
    12061 agatggtaaa ccgattgaaa acctagagta ttataataac tcaggtaaca gtcttatctt
    12121 gccatacggc aaatacacgg tcgaattgtt gacctatgat accaatgcag ccaaactaga
    12181 gtcagataaa atcgtttcct ttaccttatc agctgataat aacttccaac aagttacctt
    12241 taagatgacg atgttagcaa cttctcaaat aactgcccac tttgatcatc ttttgccaga
    12301 aggcagtcgc gttagcctta aaacagctca aggtcagctg atcccgcttg aacagtcctt
    12361 gtatgtgcct aaagcttatg gcaaaaccgt tcaagaaggc acttacgaag ttgttgtcag
    12421 cctgcctaaa ggctaccgta tcgaaggcaa cacaaaggtg aataccctac caaatgaagt
    12481 gcacgaacta tcattacgcc ttgtcaaagt aggagatgcc tcagattcaa ctggcgatca
    12541 taaggttatg tcaaaaaata attcacaggc tttgacagcc tctgccacac caaccaagac
    12601 aacgacctca gcaacagcaa aagccctacc atcagcgggt gaaaaaatgg gtctcaagtt
    12661 gcgcatagta ggtcttgtgt tactcggact tacttgcgtc tttagccgaa aaaaatcaac
    12721 caaagattga taacaaaacg caaagagaca acaaatcatc ccttttaaca gtcggacctt
    12781 tctttgagat tgagctggca gctgatcatt tcttaacaaa agttaaagag ttgagcaaag
    12841 taaggaacaa acataaagac cataaaagca agccaaactg gcttgctttt atggtgttat
    12901 tgtcgtgtgc tacgatgact aaaaaagaac aacgaacaat gacctcgaat caccaaaagg
    12961 acttgatttg atagcttccc tatgctatac taagcctatt ctttcaagaa ggactccttt
    13021 tgtggaaaag actgaaaaaa aggacactaa tctatccaaa aactccagat gagtagctgc
    13081 aaacggatgc ctttgctgtg atcaaggtga taaagcagac tggcttgtca ctacctgagc
    13141 aggtatcaaa aaaagaagct tttggctttg tcattcaaca tactgagctt tagtatttta
    13201 gaacggagac acccccagtt ttgtactcaa aaagcataaa cagctctgct gatgtgacat
    13261 ccgatttcta cgtgcgcagt gatccaaaac agctgctgtt tgctatggta aaagtggcgc
    13321 caatcgggat ttttgagacc ctaggctcaa aaataaggca tagaattcca aaggaagtcg
    13381 ctgccgtgag cacaacctaa gaaaaactat cccaaaagac tttttctgca atttgaaata
    13441 ctgaatttca gtattttttc ttttgtaact aagagcaatg aatgaggtaa aaaaggcaac
    13501 aatgtcaaaa aagaaacgaa aacactatca ggtttatgag ggattacgct gtgctatgac
    13561 gctttgtttt atcagtggct atgtcaatgc ctttacctat atgacacaag gcaaacgttt
    13621 tgcaggtgtt cagacaggca accttttgtc atttgccatt cgcttgtcag aacagcaact
    13681 gaaggaggca ctgcaatttt tacttcccat gatagttttt atgcttgggc agtcctttac
    13741 ttatttcatg caccgctggg ccattaaaaa agggctccac tggtacttat tatcaagctt
    13801 tatcttaaca gggattgctt ttggaacggc cctattcacg ccttttcttc cttccaatgt
    13861 tacggtagca gctttagcct tttttgcctc tattcaggtt gatacgttta aaaccttacg
    13921 aggagctagc tatgctaatg tgatgatgac aggaaatatc aaaaatgccg cctatttact
    13981 aaccaaaggc ttgtacgaaa aaaatcacga actaacacat atcggacgca ataccttaat
    14041 agtcatcttg gcttttgctg ttggggtggt ttgttcgacg ttgctttgca tagcttatgg
    14101 cgagtatgct ttgatgccta ttttaatgcc tttactctat gtcaattacc tgttggctca
    14161 ggaattttat cacattcaaa ccaaaatcaa accgattaaa agaacttaac ggacttgtgg
    14221 agaaagaaag ttcatttagg gtaagttttt acttaccctc cgttgctttg ctggttttgc
    14281 tgccccttaa aatatgatat aatagaccat taatagctgt tacttaacag aaggctgata
    14341 aaaaaggttc cattagcctt gagggttgaa tttaaacagg aaaaaacgaa atcctacact
    14401 atgcatctca atcgtacttt catttgagta tggttctgaa aggaaactat gatgaaaaaa
    14461 ccattttaca ttacgacacc catttattac ccatctggga aattacacat tggttctgcc
    14521 tatacaacta ttgcttgtga tgtcttggca cgctacaagc gcttgatggg ccatgaggtc
    14581 ttttacctca caggacttga tgagcacgga caaaagattc aaaccaaggc aaaagaagct
    14641 ggtattacac ctcaaaccta tgttgataac atggcaaagg atgtcaaagc cctttggcaa
    14701 ttgctagata tttcctatga cacatttatc cggacaacgg acgattacca cgaagaggtc
    14761 gttgctgctg tctttgaaaa attgctggcg caagacgaca tttaccttgg cgaatactct
    14821 ggttggtatt ctgtctctga tgaggaattt ttcactgaaa gccaattaaa agaagtcttt
    14881 agagatgaag acggtcaggt tattggaggg attgccccat caggtcatga ggtcgagtgg
    14941 gtctctgaag aatcctattt cctacgcctt agcaaatacg ctgatcgtct tgtggccttc
    15001 tttaaagagc gacctgactt tatccaacca gacgatcgta tgaatgaaat ggtgaaaaac
    15061 tttatcgagc caggtctaga agatttggct gttagccgta ctacctttac atggggtgta
    15121 cctgttccat cagacccaaa acacgtggtt tatgtgtgga ttgatgccct cttaaactac
    15181 gcgacagctc ttggttatgg tcaagctaat cacgctaact ttgataaatt ctggaatgga
    15241 acggttttcc acatggttgg aaaagatatc ttgcgttttc atagcatcta ctggccaatt
    15301 ttactcatga tgcttgattt accaatgcca gaccgcttaa ttgctcatgg ttggtttgtc
    15361 atgaaagacg gtaaaatgtc taaatcaaaa ggcaatgtgg tctatccaga aatgttagta
    15421 gagcgctttg gactggattc tcttcgttat tacctcatgc gttctttgcc agttggttca
    15481 gacgggacct ttacccctga agattatgtg ggtcgtatca actatgagtt agccaacgac
    15541 cttggcaatt tattgaaccg taccgttgcg atgatcaaca agtattttga tggcacggtg
    15601 ccagcttatg ttgacaatgg aactgccttt gatgctgact taagtcaact gattgatgct
    15661 cagctagcag actaccataa gcacatggaa gctgtagact acccacgcgc cttggaggct
    15721 gtttggacca tcatcgctcg taccaacaaa tacatcgatg aaaccgctcc ttgggtgctc
    15781 gctaaagaag atggtgacaa ggctcaacta gccagtgtca tggcacactt ggcagctagc
    15841 ttgcgcgtgg tcgctcatgt gatccaaccc tttatgatgg aaacatcagc tgctatcatg
    15901 gcccagcttg gcttagcgcc tgtttctgac ttgtcaacac ttgctctagc agattttcct
    15961 gccaatacaa aggtcgttgc caaaggcaca ccgattttcc cacgtcttga tatggaagct
    16021 gagattgact acatcaaagc ccaaatgggt gacagctcag ctatttccca agaaaaagaa
    16081 tgggtccctg aagaggttgc gctcaaatct gaaaaagacg tcatcacatt tgaaaccttt
    16141 gatgctgtgg aaatccgtgt ggcagaagtc aaggaagtgt caaaagtgga aggttcagaa
    16201 aaattgctgc gctttagagt agatgcagga gacgggcaag accgtcaaat cttgtcaggt
    16261 attgccaaat tttaccccaa cgaacaagaa ttagtgggta aaaaactaca aattgttgct
    16321 aacctgaaac cgcgtaaaat gatgaaaaaa tacatcagcc aaggcatgat tctatcagca
    16381 gagcatggag atcaactaac ggtcttaacc gttgattcct ctgttccaaa tggaagtatc
    16441 attggctgat gctgacctat tattcaaaaa acctaagcaa gaacatgtgc ttaggttttt
    16501 ttgattgcct tcaagaagga cgaataacga gatgggtgat atggcatcaa aagcataact
    16561 atcctaggac ctgtcctagg atagttatgc ttttgacaag tgaacagaga ggtcttaaaa
    16621 ctatatcttg tcataaaaaa gattgcaaaa cactatatct tgtgttatta tggtttttat
    16681 aaaagttaag tatgcttaac tttagccaaa caaaagagga cactagagcg tgtcccacaa
    16741 gacagttgag cccttcgctt ttttagtaga gtaggagtgc tcaagtcaaa aagagacatc
    16801 ccatcaaacc attgctgttt agcaggtctt tttgtgttgc tcaaaaaaaa acaattcctg
    16861 tctgtttggc gtctagtgat gacttaggct tagcgctact agacttttgt ttgaaaaata
    16921 cctcaagcct tgaaggagac aaatgaccca acattattat gaacgttcgc aatccccaat
    16981 tgaatacgcc ctatctgaaa cacaaaaaca gttgcgctcc atcaattgga attaccttaa
    17041 tgatgacaaa gatttggaag tgtggaatcg tgtcactcaa aatttttggt tgcctgaaaa
    17101 ggttcctgtt tctaatgatt taaattcttg gcgctccttg ggtgaggatt ggcaacagct
    17161 catcacaagg acctacactg ggttgacctt actagataca gtacaagcaa cggttggtga
    17221 tgtggcacaa attcagcatt cacaaaccga ccacgaacaa gtcatctata cgaactttgc
    17281 ctttatggtg gggattcatg cccgctctta cgggacgatt ttttcgaccc tttgcagcag
    17341 cgagcaaatt gaagaagcac atgaatgggt ggtctcaaca cagagcttgc aagaccgtgc
    17401 ccgcgtcttg attccttact atacgggtga tgaccctttg aaatcaaaag tagcagcagc
    17461 tatgatgcca ggatttttgc tgtatggcgg cttttacctt cctttttacc tatcagcacg
    17521 tggtaaaatg ccaaacacat ctgatatcat ccgcctgatt ttacgcgaca aagttattca
    17581 caactattac agcggttaca aataccaaca aaaagtagca cgtcttagcc cagaaaaaca
    17641 ggctgaaatg aaggcctttg tctttgactt gctctatgaa ctcatcgacc ttgaaaaagc
    17701 ttacttgaga gaactgtatg caggctttga tttggcagaa gatgctatcc gctttagcct
    17761 ttataacgct ggaaaattcc ttcaaaattt gggatacgag tcgcccttca cagatgaaga
    17821 aacgcgcgtt tcaccagaag tttttgctca gctatcagcg cgtgcagacg aaaaccatga
    17881 ctttttctca ggcaatggct catcttatgt gatggggatc accgaagaaa ccacagatga
    17941 cgattgggag ttttaaaaaa tggcagagct gattattgtg tatttttcat ctaagtccaa
    18001 taacacccat cgcttcgtcc aaaaattagg cctccctgct cagcgcatac cagtagataa
    18061 taggccactt gaagtttcaa cccattacct tttgattgtg cctacctatg cagctggtgg
    18121 ctcagatgcc aaaggagccg ttcctaaaca agtgattcgt tttttgaata atcctaacaa
    18181 tcgtaaacat tgtaagggag tgatctcttc aggaaatacc aattttggcg atacctttgc
    18241 cttagcaggc cctatcattt ctcaaaaatt gcaggtcccc ctattacacc aatttgaact
    18301 attaggcact gctacagatg tcaaaaaggt ccaggcgatt tttgcccgct taaagcatca
    18361 cacacacgac aagcaaaaac aaaccaacaa cctgattaca gaaaggacac acccatgtca
    18421 caaaccaatg cgtcatacct ctcattaaat gcactgactc gttttaaaaa accagacggc
    18481 agctaccatt ttgatagcga taaagaagct gttaggcgct acctggaaga acatgtctca
    18541 cccaatcaaa tggcttttaa ctcactagaa gataagctag cttacctcat caatgaaggg
    18601 tattatgagc aggccatttt tgatgcctat cctaacgacc ttatcaagga ggcctttcat
    18661 tatgcctatc aacaaggcta tcgcttttta aatctcatgg gcgctatgaa attttaccag
    18721 tcctatgcct taaaaacctt ggacggtaag cagtatctag aaacatttga agaccgtgct
    18781 gtgatgaatg cactcttttt agctgatgga gatcaaacct ttgtctttga cgtgattgat
    18841 gccatcttgc accgacgctt tcaaccagcc accccaacct ttttaaatgc cggaaaaaaa
    18901 cgccgtggcg aatacatttc gtgctatctt cttcgtgtcg aagacaatat ggaatctatc
    18961 tctcgcgcca ttagcaccag cttgcaactc tcaaaaagag gaggcggagt cgccttgtgc
    19021 ctcaccaacc tcagagaaat cggagcaccg ataaaaggga ttgaaaatca ggcaacaggc
    19081 atcgttcctg tcatgaaact actagaggac tctttttcct atgccaatca actaggtcag
    19141 cgccaaggag caggtgcggt ttaccttcat gcccatcacc ccgaggtcct gaccttttta
    19201 gacaccaaac gtgaaaatgc cgatgagaaa attcgcatta agtccctagc attgggactt
    19261 gtgatcccag atattacctt ccagttagcc aaagaaaaca aagacatggc tctcttttca
    19321 ccctatgata tcaagcgtgt ctatggcaag gacatgtcag acatctctat cacagaggaa
    19381 tacgataaac tgctagccaa tccagccatc aaaaagacct acatcagtgc tagaaagctc
    19441 tttcagttaa ttgcagagct acattttgag tcaggctacc cttacctctt gtttgatgac
    19501 acggtcaata agcgcaaccc tcatgccaaa aaaggcagaa tcgtcatgtc taacctgtgt
    19561 tctgaaatcg ctcaagtcag caccccaagc actttcaaag aagatttgag ttttgaaacc
    19621 attggagaag atatctgctg taatttaggg tctatcaata ttgctcaggc tatggcagat
    19681 gcgccacact ttgaacagct catcacaaca agcatcagag cacttgatcg tgtctctaga
    19741 gtgtctgacc tgaattgtgc gccttctgtt gagacaggca atgcagccaa ccatgcagta
    19801 ggattaggcg ccatgaactt acatgggttt ttggcaacca accacatcta ctatgataca
    19861 aaagaagccg ttgactttac agatctgttt ttccatgcca tggcctatca tgcttttaaa
    19921 gcctcttgcc aactagccaa agaaaaaggg gcttttgcag gattttcgtt atcaacctat
    19981 gcagatggca cttattttgc caagtatttg caagaagatg ccaagccaca aacagccaag
    20041 gttgccacat tgttgcaaga ttacggcttc acattgccaa cggtggcgga ctggcaagcc
    20101 ctagtagcag atatcaagca gtttggccta gccaatgcac acttgctagc ggttgctccg
    20161 acaggctcca tcagctactt atcatcatgc actccgagtc tacaaccagt cgttgctcct
    20221 gttgaggtcc gaaaagaagg tagcctgggc aggatttacg tccctgccta tcagattgac
    20281 caggctaact atgcttacta tgaacgtggt gcctatgagg tcggcccaaa agccatcatc
    20341 gacgttgtcg ctgctgccca aaaacacgtt gaccaagcca tctcattgac cctgtttatg
    20401 accgatcaag cgaccacacg tgaccttaac cgctcctata tccaagcttt taagcaaaac
    20461 tgtgcatcga tctattatgt gcgagtgagg caagacgtcc tagcaggcag cgaacagtat
    20521 gacgaggata gtcttgtgac agctcctgga gctagtgatg agaccaccac agagtgtcat
    20581 agctgtatga tctaacagct actagaaagc tctcgtgtcc cctaccacat gcataggatc
    20641 agtgcgctcg acctttcaag acaagcaagc atcagctctt gcttgtcttt ttttggcctc
    20701 aaagcccgtt agtctgctgc tatgcgaggc tttttttgag catcagaacc tcaaaaaaag
    20761 gacatggagt cctttttggg gtgatcggtg ttgaggctat cacaaactgc ccttgaaata
    20821 cgcttctatg tggagctttt tgtggtcctg tgacacgtaa gctccaacga cctccagctg
    20881 acagcctctt ggaaacaaga gctcaacctc tgaaggcaca gccgaataag gctcgacaaa
    20941 ggctgccttg gccccttttt tgacacagat gcgcacctcc accggtcgat gggtcatagc
    21001 gccgtttttc aaggctgtcg tgctcataaa actgtgctta gtgtagcgtg tgccaagctt
    21061 tatcttacaa aggatatgag ggtcaaactg atggttacgg tagtaagacg tgagatcagc
    21121 gtgtgaaaca ccgatatcac gcaaaaacgt ctcgtataca tagcggtata ccacaatgtt
    21181 ccacgggatg actagccggt gagtcgcagc atcgagctgg gccacctgat cccttagctc
    21241 aggcgtgagt tggctgagct cacccttggt cttgtctagg ctggtattga taagggctgc
    21301 ctgctgacag gtataagcag ccatcgcctc ttgctcagcc cttgggtaga ggagaccctt
    21361 gccccaacgc tttttaatca gtgtctcagc gcccttttga tccgaaaagg taaaataagc
    21421 aggcgtcccc tcacaaaccg cccgctcata gtgctcacag acaaaaagct cgactaagcc
    21481 ctcagtttgc cagaccagac taaaacagct aagaagaagg atcatagcca gttgatagcg
    21541 cttttttagc atagttcccc ctgacaccag cccaaaaggc tgacccttcc cctaggcctt
    21601 ttggctagct catgatacca ccagtttctc agacaggcta atctttttgt catctctttc
    21661 tccctaaaca gactctctta tcatgatatt atgctattat gagcgatttg tcaatccata
    21721 gcaaccgttt tttagttaga taagcaagct tttgacctag aggcagacaa gagtggcagt
    21781 ccctaccgtt tgctgtggtg gctaatacgg actaacacaa aatctcaaac gctttcaaaa
    21841 acagctcctg agcttaaaaa aggctgatga acagatttgt tgaacttaag agagattgcc
    21901 atgattttct aatcatttga tgtttaaaat gataaaaaca tgaacttgaa atgaaagaat
    21961 gcgagtagta aactataacc gtatcaaaaa ataatgaaat ggagtgattt tatgaaaaca
    22021 aaatcaaaac gctttttaaa cctagcaacc ctttgcttgg ccctactagg aacgactttg
    22081 ctaatgggac gtcccgtaaa tgcggaggtg acatatacag gtgagagatc aacatcagtg
    22141 aatggtcctg gtgaagatag tagcagtgag aaaacggaac aaactagtga tagtgacaaa
    22201 agagatcgga atcgtggtta tgaagagggt tataagcgcg gacaagagtc agataatcgt
    22261 gttctagata gagggactat tgaggttccc tacaatgtaa tagacggagt tgaatataag
    22321 gatggctatg aacagggatt cgcagcagga tggtacgatg gtcatccaat cacagcacta
    22381 ctagacatag cttggtccta cttaacatat gcatttgatg ttttgtttgg tggtacaaat
    22441 tcttagtaaa tggcgtattt gttgtcttaa tgtagttatt gtgacttatt gaaaagcttg
    22501 aggatacttt gcttagctca agcttttccc acacgaatct gttataatta aattatttag
    22561 ttgccacgct atctttgata acgtggcttt tcggtgtagg tgaggttatc aggatggatt
    22621 tattttcgga tcttaatagg agacaacatg aagttacaga tcgtaaagaa gacgctagag
    22681 taaacagtga ctctaattca gacaaatcaa acagatttag tatcttacga tttatttctt
    22741 gtttacgtaa tttctggagt tgtcaaatat acctgaagct gtgtattaca gtggttctac
    22801 gacgacgctt gatcttgagc tttacgactt atccgtgaat aggtatatta accaaattaa
    22861 ttttaagtaa taaggagaga tactttaaat gacaaaagca ataaagttgg ttattctcag
    22921 tttgattcta tttactacag tttttctttc agttagacaa gctagtgctg atcttatgat
    22981 ggatggagtt acttattctg aaagtacaga tagtaataca tttttatcaa actctggaga
    23041 ggtagataac atatgggaaa aggatagaga ttttggaaaa caacgaggac ttgaggctgg
    23101 taaaaatgga cttggcccaa caataaatcg aggtgatata ccagttcctg aaaaggtaaa
    23161 acataaagat aaatatcagg atgggtatca agaaggttat atccaggcat ggcatcagga
    23221 gcatccattt caaggagtta tattcgctgt attcgatgtt tttagtttga tatggggtgt
    23281 aataagtgag cttttcactt gagcgaatta gttatagtga cgctattaga gagtaatatt
    23341 atctgttgaa agtactgtaa tgtttaggct acagcgctat ttttggtaca tatagctaaa
    23401 agtactacag ttaatttttt atcacaagcc attcccacac aaatctgcta taattgggat
    23461 agtcccttta gtagtcaggc cacctctgat aggggtggct tttttgggtt ttagtgaccc
    23521 gtgtgttgag aaaggagcat gtatgccaga aaagaaagtg ttgcccgtcc taagcatggt
    23581 ggtgagcctt gtgtctctgt ttgatcatat cttctttttt gctacttata gttatctcta
    23641 cttgccgctt gtagcaagta gtctagctct tatcggtctg gtgcaaaaca aaggcaggca
    23701 aaaggtttgg tcgctagctg ggcttatcct agctgctcta gccgtggcag tagtggccta
    23761 tgcctactat gacccaaccg tcatccccta ctaaccttcc cccctctttg cacgcaatca
    23821 gcaacacaaa aagcacccct gacaggtgct ttttgtgctt tagccaacct catagcctag
    23881 taaatcctca ctgaaacagt cccttaaagt tccaccactg atcttggatg ctttcgctta
    23941 accgctgatg ccaaggttta tggtcttctt ctcttatctg ctttagcatg ctttcttcta
    24001 gctgtttttg ttgcttttcc tcttcctttt tttgaagtgc ttcttcagct tctttttctt
    24061 tttttatagt atcagagtct ctatagatat aactaccgac ataaaatccg tcttctcctt
    24121 taaatgagaa agttaatttt tctcctttct tcaaaggatc ttctcctaag ttaagaatat
    24181 aaggtactcc tgtataatat tgacgataag gatctgtttt tgtcatattt ttttcgagaa
    24241 taggactagc taaaattcct cgttctttac tgttatgatc acattgtctg taaagatata
    24301 cccaccatcc ttgagggata tatattttta ctactttact accaacatat aagtcttcta
    24361 gagtgattgt gttgccacta taatctttaa ttttttgttg aggttcatcc aaatcaaatt
    24421 ttactggctt ttgtttacta ctttgttcat cctccgctct gacgctacta gttaccccga
    24481 tggcaaagag tgccagtagc aaggttaatg tctttttcat tttttcctct ccttttcctc
    24541 attttttaag acaagggtta ttataccaat tcttgcgcta aaaagataga gagtttatgt
    24601 cttgtggttg ggaaatggcg cgactattct tggtagggtc aaacagggtg actaaagttc
    24661 ctattagcgc aacggatatc gtccataaag gagaacaata tgacatttga agagattctc
    24721 gaccctagat agttactgac tttcataggg tttcttatct agtagtattg aggattttat
    24781 cacacaaatc gtttcataga cttgttttaa aagccatcac aagtccacta aaaaggggat
    24841 aaaaaaatgc gtccgcaggc aagaaaaaag gcaccttacg gggtgtcttt taattaattt
    24901 gtcaataata attgacgttt attttgtaag tggtataata tagttaataa aaaactcgtg
    24961 aaggataaac gctgggtccc aaaatggggt aggtacttag tactgagcat tcctatgtgc
    25021 ctggggtttt tttatttgtt cgatttttta aggctctcaa caaagttttg agggtctttt
    25081 tttatttcat ttactataaa ttcaacaaac tgttgtgaat atgtataagt ctgtgttgat
    25141 cctataagat gacaatatga aaattttgtt tcactcttaa tattatagaa atcaatcact
    25201 aaatttaata cataagtatt gaaccctttt tcatagccaa gttttatcgc agactttttt
    25261 agcctttcct gaactgctgt tactacattg ctataggaat atttatgagt atctgacgga
    25321 tcttttaatt ctttaactag tgaaacaggg gtttcagcat cttttgaaat actaacaacg
    25381 aagtcagcct catctttttt cttagtaata taaagatttt gtctaatatc aattgaaaat
    25441 ttttcagaat tatactcttt actcagtaca tcaacttcat tagcttgttt gatgaatttt
    25501 tctgcaattt ctgaaggata ttttagcttt atttcctcat tggataaagg ttcgtaactt
    25561 gctgatattg ttaaaaaatt atgtgctatt gattcggtaa tatctttatt atggaatctt
    25621 ttcatttctg acgctaaatt taaaacgcat gcttgaaata atggagcata tttaatttca
    25681 tagtcttcag taataaagtg ggtgctaata tttcttaatt caattatttt ttcaagattt
    25741 aaccgaattc tggtattttc atcagaatat atctttttta aaacatattc taggctcaat
    25801 gttctttctg gattatcact gtaataaata ctaaaccctc ggttaagcat ctcagctttt
    25861 agcattagtt cccaagcatt acatataaaa aaactaaagc cttcaattcg atattttatt
    25921 gtcggtttat tatatatttc gagccccata ataaaagctt cgacactttt taaaactaat
    25981 ctttcactta aattttccat ttaattactc cgtcaaggtg acttttatta tttaagtggc
    26041 ttaatgaatt ggttaaaatc tttttagttt agtaaaattg ctatttaagg ttagccacct
    26101 ctcgtatggt cacagttgat gaattatgct atagtataga cataaaaaat agttcaaatc
    26161 ccttcttgct tgttggtgga ttttgaactg aaagcctctc tgattgcagt tggtaggctt
    26221 ttttgatgct ttttcgtact ttttatattt attacgctaa aaaatgttat acttgatgaa
    26281 gaaaaaggag agtttagaac gttaagatac ctcacagcag attgatagag gatatggaag
    26341 aaggttagct ttcccaagag atgccgtttg ggaatggtat aacaataact ggcagaagtt
    26401 ataagtaaaa caagaacaaa ttaactcaga tgatttttag acgttcccac gcgtgtgcga
    26461 atgcgtgtgc gaattgatgt tatcaataaa tcctttaata acgccttttt cgaacaggaa
    26521 acaaatttat tatcccacgc gtgtgcgaat gtgtgggcga attaattgga gaaaaaatga
    26581 gaaaatacga tatacaaaaa aggagaacaa tatgacattt gaagaaattc taccaggttt
    26641 aaaagccaag aaaaaatatg tacgtacagg ttggggtggc gctgaaaatt atgtgcagtt
    26701 gtttgatacc cttgaagtgg atgggaaagt actacaggcg acgccttatt ttctgattca
    26761 tgttactggt gcaggtgaag gtttttctat gtgggcaccg acaccatgtg atgtgttagc
    26821 agaagattgg atcgaggtca atgactaaag ttgttttagt gacgggctgt gctagtggga
    26881 ttggttgtgc acaggcccgc tattttttga gacaagggta tcacgtatat ggtgtggata
    26941 aatcggataa accggactta aacggtaatt ttcactttat caaattggat ttatcctctg
    27001 agttatcccc actatttaaa gtggtcccca gtgttgatat tttgtgtaat actgcgggga
    27061 ttttagatgc ctacaagcca cttttagacg tcagtgatga agaagtggaa cacctatttg
    27121 atattaattt ttttgcgacg gtgaagttaa cacgtcatta tcttaggcgt atggtggaaa
    27181 agcagtcagg tgttatcatc aatatgtgct caatagcaag ttttatagcg ggtggcggtg
    27241 gtgttgccta tacgagttct aagcatgccc ttgcgggatt cacgcgccag ctggctttgg
    27301 attacgccaa agatcagatt cacatctttg gtatagcacc aggtgctgtc aaaaccgcta
    27361 tgacggctag cgactttgag cctggtggct tagcagactg ggtagctcgt gagacgccaa
    27421 ttggtcgttg gactgaacca gatgaagttg ctgaattaac cggatttctt gcttcaggaa
    27481 aagcgagatc aatgcaaggc gagattgtca aaattgacgg tggctggagt ttgaaatgat
    27541 cacatgcctt agcttgagct ggcgcagtaa gccctagagg tgtgatgagt caaacagtca
    27601 aaggagatga acaaatgaaa ttagcggttt tggggacagg tatgattgtt aaggaagttt
    27661 tgcctgtctt gcagaaaatt gatggtattg atttagttgc tatcttatca acagttagaa
    27721 gtttaaagac agctaaagac ctcgctaagg catatcacat gcctctagct acgagtaaat
    27781 atgaggctgt cttaggcaat gaggagattg acacggtcta tattggactg ccgaatcacc
    27841 tgcattttgc ctatgctaag gaggctcttc tagctggtaa acatgtcatt tgtgaaaagc
    27901 cctttaccat gacagcagga gaattagatg aactggtggt aatcgctaaa aaacgaaaac
    27961 tcattttgtt agaagcgatt acgaatcagt acctgagtaa catgaccttt atcaaagagc
    28021 atcttgacca acttggcgat atcaaaattg tagaatgtaa ctattcacaa tattcttcac
    28081 gctacgatgc cttcaaacga ggtgatatcg cgccagcttt taatcctaaa atgggtggtg
    28141 gagctttacg tgatttaaac atctacaaca ttcattttgt ggtaggatta tttggtcgcc
    28201 ctaaaacggt tcaatattta gccaatgtcg aaaaaggcat tgacacatca ggcatgcttg
    28261 tcatggacta tgagcagttt aaagtggtat gtatcggggc caaagactgc actgcagaaa
    28321 tcaaatcaac catccaaggt aataaagggt cactggcagt gcttggagca acaaataccc
    28381 ttcctcaggt tcagttaagt ctacacggtc aaaaaccaca agtgattaac cacaacaagc
    28441 atgaccaccg gatgtatgag gagtttgtcg cttttaaaga catgattgac caaaaagact
    28501 ttaagaaagt gaatcaggct ttggagcata gccgagctgt catggctgtg ttggagcgag
    28561 ctgttcattc gtgattgtaa cctagtaacc attgcctttt gtgcaggtgc tatggtaatg
    28621 gttgaaagac gtgttttcac gagggttaac cccttcgtgc ttttttggca aaaataactt
    28681 gttcaggatt tgggctttct ttgtgagatg agagatgcct gacgaattga tttgattaaa
    28741 ataatgataa agccaaacga tttaagaaat gaccgttcgg aaattctgcc ccaaaaggtc
    28801 tctagaagca gtaaaatcga atttgtaagc gttgacactg ttgcataact ctgttacact
    28861 aagagaatgt catgacaaaa attacagtgt aggagtttaa ttgtttatgg aagaggatta
    28921 taacaaaaga gaacctgaga agtttacgca atttctgcgc cgtcaaaagg tcgtcttttt
    28981 tgtcgcattt tttggttatg tgtgtgccta cttggtacgc aacaatttca aactaatgtc
    29041 aaacactatt atggtgcaaa atggttggga caaggctcaa attgcgacct tgttatcgtg
    29101 tttgaccgtt tcttatggtt tagcaaaatt ctatatgggg gccttagggg atcgtgttag
    29161 cttgagaaag ctcttttcga tcagcttggg tgccagcgct ttgatttgta ttttaattgg
    29221 ttttttcaat agttcaatgg tggtattagg gatactgcta gtcttgtgtg gtgtcgtaca
    29281 aggtgccttg gcacctgcct cacaagccat gattgccaat tattttccaa ataaaacacg
    29341 cggcggagcc atcgctggat ggaacatttc tcaaaacatg ggatcagccc tcttgccatt
    29401 aaccatcgcc ttgctcacca gtatgggctt ggtggtacca gctaatggca atattttact
    29461 tgccttttta atccctggcg ttttagtgtt cttgtttgct ttgtgttgct ggaagcttgg
    29521 cggtgataac cctgagtctg agggacttga ctctcttcga acgatgtatg gtgatgcggg
    29581 cgagtcagct gttgccagtg aagaagaaaa gcataacctg tcttattggc aactcatctg
    29641 gaaatacgtt ttttgtaacc cgtcgctctt acttgttgct gctgtcaatg tggcccttta
    29701 ttttgttcgt tttgggattg aagactggat gccgatctac ttgtcacaag tagccaatat
    29761 gtcagaggct catatccatt ttgcgatttc aatattagag tgggtagcta ttccaggctc
    29821 gctggtattt gcgtggttag cggttcgtta tcctaataaa atggccaaga ttggagctat
    29881 tggacttttt gtgttagcgg ctattgtctt tgtctatgaa cgcttgactg ccacaggtgc
    29941 tccaaactat ttcttgttgc ttgttattgc aggtatttta gggtcattga tttatggccc
    30001 acagttgatc gtgaatattt taacaatcaa ctttgttcct ttaaatgttg caggaacagc
    30061 gattggtttt gtaggagtaa cagcttatct catcggcaat atgggagcaa actggctgat
    30121 gccgattttg gcagatggtt ttggctggtt ttggtcatat attgtcgttg cagccttatc
    30181 tgctttttca gcggttggtt atttgatttt agccaaacgt gaggaagaaa tcatcaaaga
    30241 ttagctaggc aaatgcctaa gaaagacaga cttattgcaa taagtcctgt cttttttagt
    30301 catcacaagt cgcaagtgac actataaaag acaagaaaat gctaggatgt ttcaggaaaa
    30361 aaagagaaaa tatgctataa tgagaaggta tttaaattat atagtaagga aaaacaaatg
    30421 acaaattatg ccattatttt agcagcgggc aaagggactc gcatgacttc tgatctccca
    30481 aaagttcttc ataaagtatc tggactaacc atgcttgagc atgtttttcg tagtgtaaaa
    30541 gcgattagtc ctgaaaaagc cgtgacggtt attggtcaca aatcagaaaa ggtacgtgct
    30601 gtcttagcag atcaatcagc ctttgtccat caaacagagc agttaggaac tggccatgcc
    30661 gtgatgatgg cagaaacaca actagaagga ctagaagggc ataccttggt gattgcagga
    30721 gatactccct tgatcactgg agaaagcctg aaaagtctga tcgattttca tgtgaatcat
    30781 aaaaatgtcg ccactatttt aacagctacg gctcaagatc catttggtta tggtcgtatt
    30841 gttcgcaaca aagatggcga agtgatcaag attgttgagc aaaaagacgc caatgagtat
    30901 gagcaacaat taaaagaaat caatacagga acctatgtgt ttgataacaa gcgtctcttt
    30961 gaagcgctca aatgcatcac taccaacaat gctcaaggag agtattacct gactgatgtt
    31021 gtggctattt ttagagcaaa caaagaaaag gtaggagcct atatcctgag agacttcaat
    31081 gaaagtcttg gtgttaatga tcgtgtggcc ttagcaacag ctgaaacagt gatgcgccaa
    31141 cgcatcaccc aaaaacatat ggtcaatggg gtgactttcc aaaatcctga aaccgtttat
    31201 attgaaagcg atgttgagat tgcaccggat gttttaattg aaggaaatgt gaccttaaaa
    31261 ggacgtacac atatcggctc aggaactgtc ttgacgaatg gtacttatat tgtggattct
    31321 gaaattggtc aaggaagtat catcaccaac tcaatgatcg aatcatctgt tttagctgca
    31381 ggagttacgg ttggccctta cgcccacctt cgaccaggaa cgaccttagg tagggaagtc
    31441 catatcggta actttgttga ggtcaagggt tctcacattg gtgaaaaaac aaaggctggg
    31501 catctgactt atattggaaa cgctcaggtt gggtcttcag tcaatgttgg ggctggaacc
    31561 atcactgtca actacgacgg ccaaaacaaa tatgaaacag tcattggaga tcacgctttt
    31621 attgggagca actcgactct cattgcacct ttggaagttg gagataatgc tttaactgca
    31681 gctggctcaa cgatttctaa gacagtacca gctgatagca ttgttattgg tcgtagccgc
    31741 caagtcacaa aagaaggtta tgccaagcgc ctagcgcatc acccaagtcg aagcaaataa
    31801 ttcaagatct atttattagt aaggaggcca ggcatgaaat ttgaagaaaa aacgcttaag
    31861 agacaaacag tttttgatgg tcatattttt aaagttgttg tggatgatgt tgaacttccc
    31921 aacaatctgg ggcaatccaa gcgagaatta atttttcatc gtggtgccgt tgctgttttg
    31981 gctattactc ctgaacgtaa gattgtcctt gtcaaacaat accgtaaggc tattgaaagt
    32041 gtctcatacg agatcccagc gggtaagcta gagattggtg aggaaggctc aaagctaaaa
    32101 gctgctgcac gtgagctgga agaagaaaca gcctatacgg ggacattgac gtttttgtat
    32161 gaattttata cagcgattgg tttttgcaac gaaaaaatca cacttttctt agcgacagac
    32221 ctaacacaag ttgccaatcc caaacctcaa gacgacgatg aagttatcga ggtcttagag
    32281 ttgacatatc aagagtgcat ggacttagtc gctcaaggta aacttgctga cgctaaaacg
    32341 ttgattgctt tgcaatacta tgccttacat tttggaggtg agcagtgatg ggaaggccat
    32401 tgttgaccga tgatatcatc gaaaaagcga gacgaatgga aacatttgag ccagatgatg
    32461 ctgtagactt tgacacaaaa gtaatgacgc taccagaaaa agatgaaaaa gcacgcattt
    32521 ataaaagccg tcggattgaa aatgccaaac gcagccaatt gcaatctaaa ttaaatgtga
    32581 ttttgatagc tgttatgctg ttaattgcca tcttggtgta tgctatcttt tatctttaaa
    32641 aaaacgtaag gaaatgatat gaaaatagga attattgctg ctatggagga ggagttgtcc
    32701 ctgctcttag caaatctttt ggatgctcaa gaacatcagg tgctttcaaa aacttactat
    32761 acgggtcgtt ttggcaagca tgagctcatt ttggtacagt caggtgttgg aaaagtgatg
    32821 tctgctatga cagttgcgat cttggctgag catttcaaag cccaagctat tatcaataca
    32881 ggatcagcag gggcagtcgc ttcacattta gcgatcggag atgtggtggt tgcagatcgg
    32941 ttagtgtatc atgatgtgga tgctactgca tttggttatg cttatggtca aatggctggt
    33001 caaccattat actatgattg tgatccacag tttgtggcta tcttcaaaca ggtcctaaaa
    33061 cacgaaaaga caaatggcca agttggtttg attgcaacag gagacagttt tgttgctggt
    33121 caggacaaga ttgaccagat caaaacagct tttagcgacg tgttagcagt agaaatggaa
    33181 ggcgcagcta ttgctcaagc agcacatact gcaggtaaac ctttcatcgt tgttcgtgcg
    33241 atgagtgata ccgcagcgca tgatgccaat attacttttg atcaatttat tatagaagct
    33301 ggcaagcgtt cggcccagat attaatgaca tttttagaaa acttacctgt ttaactcacc
    33361 ttatcgtgag acaattagct ggataatctc tattttagga gtctggtcac ctcttgtttt
    33421 gaaacctaaa aataagaatt gcaatcactt gaccaaacgc tagcatttga ctggtccaaa
    33481 atcacacctg caatatagta aagacaacac caaacttcaa ttgagaaata tccttaacgg
    33541 ctaccaaagt gacctaggga gacactactc tagctattat tactacaacc taagaaccgt
    33601 tatgggacta tcaagtgagc aagagattga agaacactat gaaaagctta agaacaagtt
    33661 acatgatatg tacaatcatt attaagtcaa aggcttaaaa atggcgacta gcccctcaaa
    33721 aagaggccac actcatttaa atttaaatga gtgtggcctc tttttgagga ggcgcaaggg
    33781 gttaaagggc tgtgacataa agttgcttag caatattttc agggatgaca agttccttgt
    33841 cgccataaca aatcgtatag gtttttgcaa aggtatcaat ttgagttaag gttagctcgg
    33901 tattgatact caggtgatgt gcttctagat actggattaa atcaaagtgg tcgtggattc
    33961 tgcttaggcg aaaccgtccc aactccgtga tggtgttgag agttgtagtg ttcatttcga
    34021 caagaggctg accatagcga ggaatagtcc ctccgtgtgg gcagaaatct ggaaaatcaa
    34081 ggatcttgtc taaacggtcg ataaaggtgt ctgagacagt gtgctctaag acttcagctt
    34141 cttggtgcac ttcttgggta ttatagccca gctggtgaat caaaaatacc tcaatcaagc
    34201 ggtgttttcg gtagaggtta gcaacaagag catagccttt gtcttttagc aaatagcctt
    34261 ttgctttatc tttgacaatc cagccttgtg aaatcatttt tttaatcatc tctgaaacgg
    34321 caggtgccga aacgtgcatc ttttctgcaa ccattttatt tgtaatcttg ggttcttgtt
    34381 ctccaatttc atagatacat ttcaagtaat cttctttatt aggcgtcata tcgtttggcc
    34441 tttctcttat ttataatgat tattatatca gaatttttag gaaaaagctt gacaaaaagc
    34501 ctaaaagagg atatccttat agcataatta actaaactta attaaataaa taatatatcc
    34561 taaggagaga aatgatggga aagagaatga gcctcatttt gggtgctttt ttatctgttt
    34621 ttcttttagt agcttgttcg tcaactggca ctaaaactgc taagagtgat aaattaaaag
    34681 tcgtggcaac caattcaatt attgccgaca tgacaaaagc tattgctggt gataaaatcg
    34741 atctgcacag cattgtgcca atcggtcaag accctcatga gtacggacca ttaccagaag
    34801 atgttgaaaa aacaagtaat gctgatgtga ttttctataa tggtatcaat ctagaagatg
    34861 gtgggcaagc ttggttcacc aaactagtga aaaatgctca aaaaacgaaa aacaaagatt
    34921 actttgccgt gtctgatggc attgatgtga tttacttgga aggtgcaagc gaaaaaggaa
    34981 aagaagatcc acatgcttgg ttaaatctcg aaaacggaat catttattca aaaaacattg
    35041 ccaaacaatt gattgcaaag gatcctaaaa acaaagaaac ttatgaaaag aacctaaaag
    35101 cttatgtggc taaattggaa aaactagaca aagaagccaa atcaaaattt gatgctattg
    35161 cagaaaataa aaaattgatt gtgactagtg aaggctgctt caagtacttt tcaaaagctt
    35221 acggtgtccc atctgcttat atctgggaaa ttaacaccga agaagaagga acaccagatc
    35281 aaatttcatc attgattgaa aaactaaaag tcatcaagcc atctgcgctt tttgtagagt
    35341 caagtgtcga tagacgccct atggaaactg tttctaaaga tagtggtatt cctatttatt
    35401 ctgagatctt tacagattca attgctaaaa aaggtaaacc tggcgatagt tattatgcta
    35461 tgatgaaatg gaaccttgac aaaatttcgg aaggtctagc aaaataagat aacaataaag
    35521 cacagcgatt ttagtgttgt gctttgtttt atttatgtaa aggagacaaa atgattacaa
    35581 ctaacaatct ttgtgtgacc tacgatggca acagtaatgc tttagaagcg attaatgtga
    35641 caattgaagg tccttctatc gttggtatta ttggtcctaa tggagctgga aaatcaacct
    35701 ttatgaaagc tatcttaaat cttattgatt atcaaggtca cgtaacggtt gatggcaaag
    35761 atggtcgtaa gcttgggcat acagtagctt acgtagaaca acgaagcatg attgactata
    35821 attttcctat tactgttaaa gaatgtgtgg cgctagggac ttatagtaaa ttaggccttt
    35881 ttcgccgagt aggaaaaaaa caatttgagc aggttgataa ggttctcaaa caagttggtt
    35941 tagaagactt tggccatcga ccgataaaat ccttatctgg tggtcagttt cagcggatgt
    36001 tggttgcgcg ttgcttgatt caagaatcag actatatttt cttagatgaa ccgtttgttg
    36061 gcattgactc ggtcagcgaa aaaatcattg tagatctttt gaaagagctc aaaatggctg
    36121 gcaaaacgat tttaattgta catcatgatt tgagcaaagt agagcattat tttgacaaac
    36181 tcatgatttt aaataaacat ttggtggctt atggcaacgt ttgtgaggta tttactgttg
    36241 ataccttgtc aaaagcttat ggcaatcatt tgattttagg aaaggagatg gtgtaaatgt
    36301 ctatgaaatt ttttgagggc ttgatgtcat accacttttt acaaaatgca ctgataacgg
    36361 ctgtagtcat tggtatcgtc tcaggtgctg tagggtgttt tattatcctt aggtcaatgt
    36421 ctcttatggg tgatgccatc tcacacgctg ttttaccagg ggttgctttg tcatttattt
    36481 taggagtcaa tttttttatt ggagcgatta tttttgggtt attagcttct gttattatta
    36541 cttatatcaa ggaaaactct gtcattaaag gagatacggc tattggtatc acctttagct
    36601 cttttttggc actgggagtc atcttgatag gggtagccaa tagttcgacg gacttatttc
    36661 atattttgtt tgggaatatt ttagctgtgc aagatagcga taagtggatt actattggtg
    36721 tttcgatttt tgttttagtg gttattagtc tctttttcaa agaactatta ttaacatcat
    36781 ttgatcctat cttagccaaa tcaatgggtg tgaaggtcaa tgcgtatcat tatttgttga
    36841 tggtcctatt aactttagtg gctgttacgg cgatgcaaag cgtgggtact atcttgattg
    36901 ttgccttatt gattacgcca gcagcgacag cttatttata tgctaatagc ttaaaagtaa
    36961 tgttagtgat gtcatcttta ctaggcgctt tagcatcggt tttagggctt tatttgggct
    37021 atacctttaa tgttgccgca gggtcaagta tcgtactgac ttctgcgatg atgtttttga
    37081 tcagtttctt tgtttcaccc aagcaaggct acctcaaaag atggatgcaa aaaaaagaaa
    37141 aaacacctta aacttttcgc tttaaacacc ttagtggttt gcaaatagta gcaaataaca
    37201 tcaaagggtg ttttttatat gtcatcaaaa gaccataaaa aaccttatca aaccaaggta
    37261 tttagcctat tatctgataa ggttttttta agcatgattt agtttttaaa gcgataatct
    37321 ttgacaatgt caattgaggt aatcgtaatg tcttgttctg gtttatcatt ttggttgata
    37381 gaagtcgcgg caattttatc gacaacatcc ataccatcaa tgacttgacc aaatacagta
    37441 taaccgccat ctaagcttgg attgccgcca tgctcatagg cagagatgat aggttttggg
    37501 tagttggtac ttgataatcc cttgctttga tttttcttgt tttggttgat ataaaattgg
    37561 ctaccgttcg tattagcgcc agcatttgcc atggcaagag caccgcgaat atgatataaa
    37621 aatggagaga tttcgttgac aaagccattg ccagcatctt ttttaggatc cttgcccttc
    37681 caaatcgatt caccacctgt gccatctcct ttggggtcac ctgattgaat cataaagtcg
    37741 ttgatcacac gatggaaagt aaggttatca tagtagcctt ttttagcatg ggtgaggaag
    37801 ttctcaacag ctaagggagc atattttggg aataacttaa gggtaatgtc cccttgactt
    37861 gtcctcatta cgaccttagc ttcttctttg ccgacttctt tggttagttg tggaaattgg
    37921 ctagcatcag ctttgagagc tttttgaatg ctttcttcat aggctttaga agctgcttcg
    37981 ctttcttctt tggcagtttt ttcatcaatg tatttatcgc cttttatagc gcggtcaaca
    38041 gactcacaag cactcaaact aagtaaacta atggctacta aactgagaga taataatttt
    38101 ttcatgtcta ctcctaagaa tgattttctt tattttatca taaaatgcaa cagaaaatag
    38161 tagtaaagag ttaaaaacgc ctatttttgt gttttatgat ctaaccttgg ttaaaaggct
    38221 gctacgactg ttattatagc acaagatgct atagaaaaac ttaaaacacc ttggtttttt
    38281 agagctattt cctaatagtt aaaaaatggt ataatagtgt tatggttaaa agaaatcaaa
    38341 gaagaaaaag tgcgcctaag aagcgtctga caaaagcaga agtggaaaag caacgtgcca
    38401 ttaagaggat gattttatct gttttaatgg ctttgttgct tatttttgcg atgcttcgct
    38461 tgggcgtctt tggcgtgaca acttataata tgattcgttt tttggtgggt agtttagcct
    38521 atccgtttat gtttgcctgg ttaatttact tattttgttt taaatggtta cggcaaaaag
    38581 atggaatgat tgcgggagtt gttattgcct ttttgggatt gctagttgag tggcacgcct
    38641 tcttatttgc gatgcctagg atgtttgatc aagatatttt tctaagcact gctcggctaa
    38701 ttacaagaga tttactagcc ctgcgcgtga ctgaatttgt tggtggagga atgcttggtg
    38761 cattacttta taaacccata gcctttttat tttcgaatat cggctcttac tttattggtt
    38821 ttttgtttat cttattagga ttatttctaa tgacgccttg ggatatctat gatgtgagtc
    38881 actttgtgaa agaggctgtt gataaactag cagtggctta tcaggaaaat aaagaaaagc
    38941 ggttcatcaa acgagaagag caccgcttac aagctgaaaa agaggcttta gagaaacaag
    39001 cacaagagga agaaaaacgt ctagcagaat tgacggttga tcctgagacg ggagagattg
    39061 ttgaggatag tcagtctcaa gtcagctatg atttggctga ggatatgaca aaagaaccag
    39121 agattcttgc ttatgatagt cacctcaaag acgatgaggc aagcttattt gaccaagaag
    39181 acttggctta cgctcacgag aaaattgggg cttatgactc tttatctgct ttagcatctt
    39241 ctgaagatga gatggatatg gatgaacctg ttgaagttga tttcacacca aaaacccatc
    39301 ttctttataa acttccaacg atagatttat ttgcaccaga taagcccaaa aaccagtcca
    39361 aagagaaaaa cttagtccgc aaaaatatca aggtgcttga agataccttc caaagttttg
    39421 ggattgatgt caaggtagaa cgagcagaaa tcgggccttc cgtcaccaaa tatgaaatca
    39481 agccagctgt cggggtccga gttaatcgta tttcaaatct tgctgatgat ttggcacttg
    39541 ctctggctgc taaagatgtt cgtatagaag caccaattcc tggaaaatcc ttaataggta
    39601 ttgaagttcc taactcagaa attgcaacgg tttctttccg cgaactttgg gaacaatctg
    39661 atgccaatcc tgaaaacctt ttagaagtac cactaggtaa agctgttaat ggtaacgctc
    39721 gcagttttaa cttagctaga atgccgcatc ttttggtagc tggttcaact ggttcaggta
    39781 aatcggttgc tgttaatggc attatttcaa gtattctgat gaaggctaga ccagaccaag
    39841 tgaaattttt gatggtcgac cctaagatgg ttgagttgtc tgtttataat gatattcccc
    39901 atttgctgat tccagtagtg accaatcctc gtaaagccag caaggcgttg caaaaagtgg
    39961 ttgatgagat ggaaaatcgc tatgaactct ttagtaaagt cggggttcga aatattgctg
    40021 gttacaatgc aaaagttgag gattacaata ggcaatctga gcaaaaacaa atgcctttac
    40081 cattgattgt ggttattgtg gatgagttag ctgatttgat gatggtggct agtaaagaag
    40141 tggaagacgc tattatccgt ctggggcaaa aggcgcgtgc ggcaggtatt cacatgattc
    40201 ttgcaaccca aagaccatct gtggatgtta tttctggact gattaaggcc aatgtgccat
    40261 cccgtattgc atttgccgta tcttcaggaa cagatagtcg aacgattctg gatgaaaatg
    40321 gcgctgaaaa gctcttagga cgtggagata tgctctttaa gccgattgat gaaaatcacc
    40381 ctgttcgtct gcaagggtct ttcatctcag atgatgatgt ggaacgaatt gtaaacttta
    40441 tcaaagacca agctgaagcg gattatgatg acgcctttga tcctggtgaa gttagcgaca
    40501 atgatcctgg tttttctgga aatggtggag ctgctgaagg tgatcctctt tttgaagaag
    40561 caaaagcctt ggtcttagaa acacaaaaag ctagtgcctc aatgattcag aggcgtttgt
    40621 cggttggatt taatcgtgcc acgcgcctga tggatgaatt ggaagaagca ggtgttatcg
    40681 gtccagcaga aggaaccaaa cctcgtaagg tattgcagac aaactaaaag aacctgacgt
    40741 ctcatcatga gatgtcaggt tcttttttgg tgatgtcagg ccagttgatg agatgcctat
    40801 gctaatgtaa aaataaagat aactagaata aggtagaaaa taacggtgac taaaaagcca
    40861 actcgccaaa atagcttcat aaagcgatgg taagaaaacg actgagttcg gatgactagc
    40921 agtagtgaaa tgacgatggc tagcagcgac atgataataa ggtaataagg cagtaaatta
    40981 tgggtgaaaa attttcctga gacaagcaca atttctatcg caaaaagtaa aagtgcgaca
    41041 tctggaaatt taaatccctt tttattaagt ttaaatagag gggttacaat catggcaaaa
    41101 agaggcgtta caatcaagaa agctaaggca gttaatttat agatcatcat aggtctattt
    41161 tatactcaaa tcccttactt gtaaactgat acttacctgt tgtgatagaa actgatcttt
    41221 gagagggaaa gagcctactt caatttaaac attacaaaag gcatcagcta ttttaacaaa
    41281 aagacttgat ttattttggc aataagctat aatggtaagg tatgcaatat tgcatatctg
    41341 tgggaggtaa aaatctcaat taccgccaaa accacaacag gaggattttt aaaatggcta
    41401 aaaaagtcga aaaacttgta aaacttcaaa tccctgctgg taaagctaca ccagctccac
    41461 cagttggacc agctcttggt caagcaggta tcaacatcat gggcttcact aaagaattta
    41521 acgctcgtac agctgatcaa gctggtatga tcatcccagt tgttatctca gtttatgaag
    41581 acaaatcatt tgatttcatc actaaaacac caccagctgc tgttcttttg aaaaaagctg
    41641 caggtgttga aaaaggatca ggtacaccta acactactaa ggttgcgaca gttactcgtg
    41701 cacaagtaca agaaattgct gaaactaaga tgccagattt gaacgctgca aacattgaag
    41761 ctgcaatgcg tatgatcgaa ggtactgctc gttctatggg attcactgtt actgactagt
    41821 cagtcaagaa cccctattac ccgcacgact tcatcataag agatgagtga cgtgggagat
    41881 tttaaatcaa atcgatatga ccacattaca aggagaattt taaaatggct aaaaaaagca
    41941 aacaaatgcg tgctgcactt gaaaaagtag atagcacaaa agcgtacagt gtagaagaag
    42001 ctgtagcatt agtaaaagaa acgaacttcg caaaatttga tgcgtctgtt gaagttgctt
    42061 acaacttgaa cattgacgtt cgtaaagcag accaacaaat ccgtggcgca atggtattgc
    42121 caaacggaac tggtaaaaca caacgtgttc ttgtttttgc acgtggtgca aaagctgaag
    42181 aagcaaaagc agctggtgca gacttcgtag gtgaagatga ccttgttgca aaaatcaatg
    42241 gtggatggct tgactttgac gttgttatcg caacgccaga catgatggct atcgtaggtc
    42301 gccttggacg tgtccttgga cctcgtaact tgatgccaaa ccctaaaact ggtacagtaa
    42361 cgatggatgt tgctaaagcc gttgaagagt ctaaaggtgg taaaatcact taccgtgctg
    42421 acaaagcagg taatgttcaa gctcttattg gtaaagtttc atttgatgct gacaaattgg
    42481 ttgaaaactt caaagccttc cacgatgtaa tggctaaagc taaacctgca acagctaaag
    42541 gaacttacat ggcaaacgtc tcaatcacat caacacaagg tgttggtatc aaggttgatc
    42601 ctaactcact ttaagaaaaa aattagggca acgcctaatc atagcaaaaa gacaaatttc
    42661 tgaagacaaa tcttcactag aggtttgtct tttttatggt ttaaaatgga atgcaaacaa
    42721 aaaagtgtag gcgataatac catgaaagga gttgattctc ttaatgagat gtggtgttaa
    42781 cacatcatga gctcacaaaa aatgataaag gaagtatcgg tggtgttaaa aaagggattt
    42841 taattgacat ttattagcct ctaaaatgtc ctttccctat tcataattga gggtttgtgg
    42901 taaaatagta aggacaaact aaggagaaca tagtagtgga acctaaatat caacgtatat
    42961 taattaagtt atctggtgaa gcattagcag gtgaaaaagg agttggcatt gacattccaa
    43021 ctgttcaggc tattgcaaaa gaaattgccg aagttcatgt gtcgggagta cagatcgctc
    43081 ttgttattgg tggaggcaat ctctggcgtg gagagcctgc agcagacgct ggaatggacc
    43141 gtgttcaggc tgattacact ggcatgcttg gaacggtgat gaatgcccta gtcatggctg
    43201 atagtcttca acattatggt gttgataccc gtgtgcaaac agctattcct atgcaaaatg
    43261 tagcagaacc ttatattcgc ggacgtgcct tgcgccatct agaaaaaaat cggattgttg
    43321 tttttggagc tggtattggc tcgccttatt tttcaacaga caccaccgcg gcactgcgtg
    43381 ctgctgagat tgaagcagat gctattttaa tggcaaaaaa tggtgtggat ggggtctata
    43441 atgctgatcc taaaaaagat gctaatgcgg ttaaatttga tgaattaaca catggtgaag
    43501 tgatcaaacg tggtctcaaa atcatggatg caacggcatc gaccttatcg atggataacg
    43561 atattgattt ggtggttttc aatatgaatg aagctggcaa tattcaacgt gttgtctttg
    43621 gagaacatat tggaactact gtatcaaata aagtttgtga ctaaaagtta gaaaagaaag
    43681 agagtaatta tcatggcaaa tgcaattatt gaaactgcaa aagaacgttt tgcacaatcc
    43741 catcagtctt tatcacgtga atatgccagc attcgtgcgg gtcgtgccaa cgctagtctt
    43801 ttagaccgta tccaagttga ttattacggg gcaccgacac cattaaatca attggcttca
    43861 atcactgtac cagaagcgcg tgtcttattg atctcgcctt ttgataaatc ttctatcaaa
    43921 gatatcgagc gcgctcttaa cgcatcagat ttaggcatta cacctgctaa cgatggctct
    43981 gtcattcgtt tggttattcc agctttgacc gaagaaacac gtaaagaatt agccaaagaa
    44041 gtgaaaaaag ttggtgaaaa tgctaaaatt gcaatccgta atatccgccg tgatgctatg
    44101 gatgatgcta aaaagcaaga aaaagcaaaa gaaatcactg aagatgagtt aaaaacactt
    44161 gagaaagata tccaaaaagc aaccgatgat gctatcaaag aaattgaccg catgacggct
    44221 gaaaaagaaa aagaattgct ctcagtgtaa caggatttct acgaaaaata gacgactata
    44281 gacacaaaaa gataggtgac tatttcagaa gcgtttggtt ttgatttgtc cctatttttt
    44341 taaagaaaga aaaaagatat gaatgattta ctagcaacag tcattactgg gcttattaaa
    44401 gaagaaaacg ctaatgacta ttttatccaa aaagaggggt ttacctttac cttgtctaaa
    44461 gcagaaggag aacgccagat tggtgatatg gtcacaggct ttgcctatac agacataaag
    44521 caaaaggcac gtctcacaac caaagagatc cgttcaacac ggacaagtta tggctggggg
    44581 gaagtgacag aggttcgtcg tgacctaggc gtttttgtcg atacaggaat tccaaataaa
    44641 gaaattgtgg tttctttgga cgtgttgcct gaaatgaaag aactatggcc taaaaaaggg
    44701 gataaacttt acattagttt ggatgtggat aaaaaagacc gtatttgggg acttccagca
    44761 gagcctgagg tctttcaaaa gatggctagc cctgcataca ataatatgca aaatcaacat
    44821 tggccagcaa ttgtttaccg cctaaaatta acaggaacgt ttgtttacct gcctgaaaac
    44881 aacatgttag gctttattca cccaagtgaa cgctacgcag aaccgcgctt aggtcaggtt
    44941 ttagatgccc gtgtgattgg gtttagagag gtcgatcgta ccctaaactt gtcgttgaaa
    45001 ccacgttctt ttgagatgtt ggagaatgac gctcagatga ttgtcaccta tcttgaagcc
    45061 aatggtggtt tcatgacctt aaatgacaaa tcaagtccag aagagattaa agcaaccttt
    45121 ggtatttcaa aaggccagtt taaaaaagcc ttgggtggat tgatgaaagc taaacgcatc
    45181 aaacaagacg ccacaggaac tgaattaata ggataaaaat gctttgccac tggcaaagtt
    45241 ttttgttaca atgaagacca ttaagtgaag aaaaagggga tatagagaat ggaaagagcc
    45301 atttttgcag gaggttgttt ctggtgtatg gtgcaacctt ttgaggagca agcaggtatt
    45361 ttgtcagtca gaagtggcta cacaggtggg catctcccaa atcctagcta tgaacaagtt
    45421 tgtgccaaaa caacaggaca tacagaagct gttgaaatta tttttgaccc taagcaaatc
    45481 gcttataaag atttggtaga gctctattgg gcgcagacgg atccaacaga cgcctttggg
    45541 caatttgaag atcgtgggga caactaccgt cctgtcattt actacacaac ggaaagacaa
    45601 aaagaaattg cagagcaatc aaaagcaaac ttgcaagctt caggacgttt tgaccaaccc
    45661 attgtcacca ctattgaacc agcagagcca ttttatctcg cagaggatta tcaccaagga
    45721 ttttataaaa agaatcccaa gcggtatgca caaagcagtg ctattcgtca tcagttttta
    45781 gaggagaact ggtcatgaga aaatcatttt acagctggct gatgacacaa cgtaacccta
    45841 aatcaaatga acctgtggcg attttagcag atttggtgtt tgatgacacc acttttccaa
    45901 agcataccaa tgattttgaa ctcattagtc ggtatctaga agatcaagct agtttttcct
    45961 ttaatttagg tcaatttgat gaaatctggg aagattatct agcacattaa tacgtggata
    46021 aaaaagagtc atatcgactc ttttgaaggg ttatcacgtt attattacaa aatgacatca
    46081 ctttctttca aaaaaatgac aagctacttt ttttcttaaa aatatgctat gatatagctt
    46141 agaaaaaaaa taaaaaggaa gcagagatga ttattactaa aaagagctta tttgtgacaa
    46201 gtgtcgcttt gtcgttagca cctttggcga cagcgcaggc acaagagtgg acaccacgat
    46261 cagttacaga aatcaagtct gaactcgtcc tagttgataa tgtttttact tatactgtaa
    46321 aatacggtga cactttaagc acaattgctg aagcaatggg aattgatgtg catgtcttag
    46381 gagatattaa tcatattgct aatattgact taatttttcc agacacgatc ctaacagcaa
    46441 actacaacca acacggtcag gcaacgactt tgacggttca agcgcctgct tctagtccag
    46501 ctagcgttag tcatgtacct agcagtgagc cattacccca agcatctgcc acctctcaat
    46561 cgactgttcc tatggcacca tctgcgacac catctgatgt cccaacgaca ccattagcat
    46621 ctgcaaagcc agatagtttt gtgacagcgt catctgagct cacatcatca acgaatgatg
    46681 tttcgactga gttgtctagc gaatcacaaa agcagccaga agtaccacaa gaagcagttc
    46741 caactcctaa agcagctgaa acgactgaag tcgaacctaa gacagacatc tcagaagacc
    46801 caacttcagc taataggcct gtacctaacg agagtgcttc agaagaagtt tcttctgcgg
    46861 ccccagcaca agccccagca gaaaaagaag aaacctctgc gccagcagca caaaaagctg
    46921 tagctgacac cacaagtgtt gcaacctcaa acggcctttc ttacgctcca aaccatgcct
    46981 acaatccaat gaatgcaggg cttcaaccac aaacagcagc cttcaaagaa gaagtggctt
    47041 ctgcctttgg tattacgtca tttagtggtt accgtccagg tgatccagga gatcatggta
    47101 aaggtttggc cattgatttt atggtgcctg aaaattctgc tcttggtgat caagttgctc
    47161 aatatgccat tgaccatatg gcagagcgtg gtatttcata cgttatttgg aaacagcgat
    47221 tctatgcgcc atttgcaagt atttacggac cagcttacac atggaacccc atgccagatc
    47281 gcggcagtat tacagaaaac cattatgatc atgttcatgt ctcctttaat gcttaattca
    47341 tgctatcaaa aaaaactcac gtttaggcgt gagttttttg acaattctga cagagtaagc
    47401 cctataagag gctgagatac gcttttaata cctgttgttt ttctcaccct ttagacagtt
    47461 ttaacgttat gtctaaaaga gatggttttt attagcgcaa atatgggttt aggggtaaaa
    47521 tataggtaat taacctgata tgatcatgat aaaggtagaa gaatacctat tatttcgtga
    47581 caactgagca atctgtctta cctttggagt gatgatatca ctttgcttga ctattcaagg
    47641 aggtcttgaa atgtattata ctagtggtaa ttacgaagct tttgcaacac ctcgaaaacc
    47701 tgaaggggta gatcagaaat cagcttatat tgttggcact ggtttagctg gtttagcagc
    47761 agctgttttc cttattcgcg atgggcatat ggctggggaa cgcattcatc tgtttgagga
    47821 attgccttta gcaggtggtt ctttagatgg tattgaaaag cctcatcttg gttttgtgac
    47881 ccgtggtggt cgtgagatgg aaaatcattt tgagtgtatg tgggacatgt atcgctctat
    47941 tccctcactg gaaattcccg gtgcgtctta tttagatgaa ttttattggt tggataagga
    48001 tgatcctaac tcatccaact gtcgtttgat tcacaagaga ggaaatcgtg tggatgatga
    48061 cggccagtat acgctcggta aacagtcaaa agaattaatc catttaatca tgaagacaga
    48121 agaatctcta ggagaccaaa ccattgaaga gttcttctca gaagatttct ttaagagtaa
    48181 tttttgggtg tattgggcaa ccatgtttgc ttttgaaaaa tggcactctg ctgtagaaat
    48241 gcggcgctat gcgatgaggt ttatccacca tattgatggt ttgccagatt ttacctccct
    48301 caagttcaac aaatataacc aatatgactc tatggtcaaa ccgattattg cttacctaga
    48361 atcacacgac gttgacatcc aatttgacac aaaagtcact gatattcagg tggaacaaac
    48421 agctggtaaa aaggtagcaa aaaccatcca tatgacggtg tctggggagg ctaaggcgat
    48481 tgagctaaca cctgatgatt tggtttttgt gaccaatggt tctattactg aaagcagcac
    48541 atacggtagt catcacgaag tggctaagcc aaccaaagcg ttaggtggtt cttggaattt
    48601 atgggaaaat ctagctgctc aatcagatga ttttggtcat cctaaagtgt tttaccagga
    48661 cttgcctgct gaaagctggt ttgtgtctgc cacagcaacc ataaaacacc cagctatcga
    48721 gccttatatt gaacgtttga cccaccgtga cttgcacgat ggcaaagtga acactggcgg
    48781 catcatcact attacagatt ctaactggat gatgagcttt gccattcacc gtcaacctca
    48841 ttttaaagaa caaaaagaaa atgagaccac tgtctggatt tacggtcttt attccaatag
    48901 taagggcaat tacgtccaca agaaaattga ggagtgtaca ggtcaagaaa tcacagaaga
    48961 atggttgtac caccttgggg tacctgttga taaaatcaag gacttagcga gtcaggacta
    49021 tatcaataca gttcctgttt acatgcctta tattacgagt tactttatgc cacgcgtcaa
    49081 aggagaccgt ccgaaagtta tcccagatgg ttcagtcaac ttggccttta ttggtaactt
    49141 tgcggaatct ccatctcgag atacggtctt tacgactgag tattctattc gtactgccat
    49201 ggaagcagtg tatagcttct tgaatgtgga acgaggcatc ccagaagtct ttaattcagc
    49261 ctatgatatt cgtgaattgc tcaaagcctt ttattacctt aatgataaaa aggcaatcaa
    49321 ggatatggat ttgccaattc ctgcactgat tgagaaaatc ggacataaaa aaatcaagga
    49381 tacctttatc gaagaattgc tcaaagatgc taatcttatt taacatgcct tagagtagtt
    49441 aaagctgata agtttaggct tatcagcttt tttgatgatt tatagaaaag tgataaagga
    49501 aaagtctgac gtgaacgtca cataagaatt taaaatttgt tataatgtaa gcaataaaga
    49561 tgaaagaaag agggactcta tttgcaagag tattctattg acattacctt aacccatcct
    49621 gatgatgttt tagctctttt tggtagcaac gagcgtcatt tgaagctaat agaagctcat
    49681 ttaggagtta ttgttcacgc aagaaccgag cgagtccaag tgattggtga tgatgaagaa
    49741 gctgtggaat tggctcgatt gaccatcaaa gccctactgg ttctagtggg tcgtggcatg
    49801 gtggtcaaca catcagatgt ggtgacagct ttatctatgg cagaatctca tcagattgac
    49861 caatttatgg cgctttatga agaagaaatc attaaagata actatggtaa ggcaatacga
    49921 gtcaaaacat taggtcaaaa aacctatgtc gatagtgtca aacgtcatga tgtggttttt
    49981 ggtgtaggac ctgcagggac agggaaaacc ttcttagctg ttacacttgc agtcactgct
    50041 ctgaaaagag gacaggtaaa gcgtattatt ttgacgcgtc ctgcggtaga agctggtgaa
    50101 agcctaggtt ttttaccagg cgatttgaaa gaaaaggtgg atccttacct cagaccggtt
    50161 tacgatgccc tttatcacat tttaggcaag gaacaaacca cacgcctgat ggaacgagat
    50221 gtgattgaga ttgctccgtt agcttatatg cggggtcgta ctctggatga cgcttttgtt
    50281 atcttagatg aggctcaaaa cacaaccatc atgcaaatga agatgttttt gacccgtctt
    50341 ggttttaatt ctaaaatgat tgtcaatgga gatacgagtc agattgacct ccctcgaaat
    50401 gtcaagtctg gtttgattga tgctactcag aaattacaag gcattaaaca gattgatttt
    50461 gtctatttct ctgctaagga tgttgtccga catcctgttg tggctgatat tatcaaggct
    50521 tatgaaacgt cctcagagga gacgaaggac ttactaaaac ctaaggctag tgacgttgaa
    50581 gctgattacc agccaggctt gacaaaatac cctgtgatcg gtcaagagca ctaagacttt
    50641 tacgatgatg tttaatatgg cctttttaag gaggattcta tggatgattt aaccaaagct
    50701 attatggcag atgaggctaa tctctcctat accgaaagag gtatttttcc tttatatgat
    50761 gctcctcaaa cagctaggat tattattgtt ggccaagctc ctggaatagt agctcaagaa
    50821 accaaacttt actggaatga tcgtagtggc atccgcttac gagactggct aggtgtggac
    50881 aatgacacct tttaccactc aggattgttt ggcattatcc ctatggattt ctattatcct
    50941 ggtaagggaa aatccggtga cttaccacct agagaaggtt ttgcggctaa gtggcacccg
    51001 ccattaagag cattgatgcc agaagttgaa ttgacgattt tggttggtcg ctatgctcag
    51061 gacttttacc ttggtaacaa ggcttacaaa accttaactg aaacagtccg tcactttgag
    51121 gagtacttgc cagactattt tccacttgtt catccttctc caagaaacca attgtggtta
    51181 gctaagaacc cctggtttga gcaggattta ttacctatct tgcaaaaacg tgtggaggca
    51241 attctaacca aataggccct gatttaccta gcattcccat ttttaagggg cttgtggtat
    51301 aatgggtaaa taacaaatgc tgattgaaag gataagggaa attatctgtc agataataat
    51361 gggtgcccaa cataccaaat gaggtgggca gcccttccct aacaattaac cttatgtata
    51421 tcgagatgat tgacgaaacg ggacaagttt cgcaagagat tatggagcaa acacttgatt
    51481 tgctcaattt tgctgctcaa aagacgggca aagaagaaaa agaaatgtct gtgacctttg
    51541 tgaccaatga aagaagtcat gaactcaact tagaataccg agatactgat cgtccaacag
    51601 atgtgatttc tctagaatat aagccagaaa cgcctatttt atttagtcaa gaggatttgg
    51661 ctgctgatcc tagtttggca gagatgatgg cagagtttga tgcttatatt ggcgaattgt
    51721 ttatttctat tgacaaggcg cgtgagcagt cccaagaata tgggcactct tttgagcgtg
    51781 aaatgggatt tttagctgtt catggattct tacatattaa tgggtatgat cactacaccc
    51841 ttgaagaaga aaaagagatg tttaccttac aggaagagat tttgactgct tatggcctta
    51901 cacgacaata ataccaccaa acggaaatgg aaaaacagaa ccattacctc aagcttggag
    51961 tttgccttga caggggtttt cacagctttt aaggaagaac gcaatctcag aagccacctt
    52021 ttgtctgcct gtttagcttg tgttgctggt ttatctttta gcatttcagc catcgaatgg
    52081 ttatttttac ttctagccat ttttttggtc attaccttag aaattgtcaa ttctgctatt
    52141 gaaaatgtag ttgatttggc tagtgactat cacttttcta tgctagctaa aaatgccaag
    52201 gatatggcag caggtgctgt tttgatgatt tctggctatg ctgtcttgac aggacttatt
    52261 atttttattc ctaaaatttg gaatattttc gttcattaaa aagaaaggaa tgggctatcc
    52321 tatgtgatga tggcatagga gaataaggaa aggacaagac ggttaagctt agtgacaagc
    52381 ttgatctgaa gccctaccgt taaggcccgt aattatctat gtttaaatca ggctttgtag
    52441 ccattcttgg tcgtccaaat gttggcaaat ccaccttttt aaatcacgtc atggggcaaa
    52501 aaattgccat catgagtgac aaggctcaga ccacccgtaa taaaattatg ggcatttaca
    52561 ccacagaaac agaacaaatt gtctttattg atacgccagg tattcataaa ccaaagaccg
    52621 cccttggtga ttttatggtt gaatctgctt atagtacttt acgtgaagtt gagacagttc
    52681 ttttcatggt tcctgccgat gaaaagcgtg gtaagggtga cgacatgatt atcgagcggc
    52741 taaaggcagc taagattcct gttattttag tcatcaacaa aattgataag gttcatccag
    52801 accaactttt ggaacagatt gatgacttcc gtagccaaat ggattttaaa gaagtggtcc
    52861 caatttctgc cctagaaggt aataatgtgc caaccctaat caagttatta actgataatc
    52921 ttgaagaagg tttccaatat tttccagaag atcagattac tgatcatcca gaacgtttcc
    52981 ttgtgtcaga aatggttcgt gagaaggtac tgcatttgac gcaacaagag gttccacatt
    53041 ccgtagctgt tgttgtcgaa tccatgaagc gagatgaaga gactgataaa gtgcatatcc
    53101 gtgcaaccat tatggtggag cgcgatagcc aaaaaggcat catcatcggt aaacaaggag
    53161 ccatgctcaa aaaaatcgga aaaatggcgc gccgtgatat tgaactcatg ttaggtgaca
    53221 aggtctactt agaaacgtgg gtcaaagtca agaaaaactg gcgggataaa aagcttgatt
    53281 tagctgattt tggctataat gagaaagaat actaacatag taaagcgaga tcatatgcca
    53341 caagactaca tttcttatat ccgctccaaa gttgggcatg ataagattat tcttaacttt
    53401 gctggtggga ttttgaccaa tgatgacggc aaggtgctga tgcagttgcg tggtgataag
    53461 aaaacctggg ctattcctgg tggcactatg gaactgggtg agagctcttt agagacttgc
    53521 aaacgtgagt tcttagagga aaccggaatt gaggttgaag ctgttcgctt actgaatgtt
    53581 tacactcatt ttgaggaagt ttatcccaac ggtgatgctg ttcagactat tgtctttatc
    53641 tatgaactaa cggctgtttc tgatatggct attgataact ttcataatga ggaaacgctc
    53701 aagttacagt ttttctctca tgaggagata gcagagttag agagtgtctc agccaaacat
    53761 cgcctgatgt tagaggaata ttttagtgat agctttgcta tggggcatta agaactctct
    53821 aggacagttg gagtattttt ggagattggc ttgttaaaaa aatttttgaa agacgatgtt
    53881 tcgagagctt atgctctctt tttttgcttc caatttttct gattaagtct gaataatttt
    53941 gttaaatgtt aacaggattt tctttccaat tgatactagc agacatcaaa catttgtttt
    54001 agagttatga cgaattgcca cctagccatg catgacttag gcaagttgaa cctaactgtg
    54061 gcaatagact tggaaggggt gacaagaatc atttcctaaa agaattgatg aagtgcctat
    54121 ccattattcg aattgtaaag ttcgtctaag taaagttgaa tttgatctcg aatggacttt
    54181 gatgatttat gacttgttgt gtcaataaca ccaaaaactc gataatgatt tttaaatatt
    54241 tcctcgtaat taatatgatt tccgattaga ataatatgag catgaggata acgcatacgt
    54301 atttcgttta gaaggtcata tacttgctca gatttaaaaa agtatgattt atgataaaat
    54361 aaacctgaca tttgtattta taatctaagt ttttcccact aataatttga gtttttagaa
    54421 agtatctctt gaggtaatag ttaatataga tagatatcat atatcctaaa agagaacgat
    54481 gtcttgtaag tattttagtc ttcgaaaata cttacaagac atcgttctaa ggcttcttca
    54541 tttgggaaaa ccactctctt cttgttttgt cgcttaattt ctttattgag tgattcaatc
    54601 aagtttgtag agtaaatgct agaccaaatg tgatgtggga attgatagaa agtaaggaga
    54661 ttttccgtcg tttcaagtga tgccatgacc tttttataac gaggcttcca ctcagaaaca
    54721 agtggtgacc atacatgcgc tcaataatgt cactgatttc gcgtgtcgta acgccagtct
    54781 gatagagttt gatcaccatc tcttccaagt ggtcatctcg tctagcataa gatggtaata
    54841 aaactggtga aaactcgccg tttcgatctc ttgggatgat taaattgact aagccatact
    54901 ttgtttcaaa ctgacgagaa taagtcccat tacggctatt acctgtgttg taaccttctt
    54961 tttcataagg ttcataacca agaaaagctg atagttcaac ttgcaagagg tcattcatag
    55021 ctatttctaa agaggagcga aagaattcat caatatcttg tttttgtgct aggaagttaa
    55081 gtaattctgt ggtaaactga gtcatgggaa tgaatctctt tctagtgaag tgtcgtaact
    55141 ctactataca agatttattc ctttttgtgt gtttacacaa gatattttac actaccatca
    55201 aaaatcttaa aaggtattta taaaagcatg aatggtatta tttaaacttc ttaattaatt
    55261 aactattgtc acagcgtaag tgtagagagg ataaaaagac atttcatgat gaaaaacagc
    55321 cttttaagat tttgaaacca tgatactgtt ctttatgata ttctgtacta gctcgaggtt
    55381 gcaacgagac aaatttaaga attatgaaaa gaagttattc gatatggagg taaagaaact
    55441 ggaaacattt caccaaatga ctatagaaaa gcttgccaag gttgagggtg gtaagaataa
    55501 ttggcaggca aatgtcagtg gggttatcgc tgcaggtagt gctggagctg ctataggttt
    55561 tccagtttgc ggtgtagcct gtggttatat tggagctaaa acagctatta ctctttgggc
    55621 tggtgtaaca ggagctacag gcggattcta gaggaaagaa aggatgacaa caatgaagga
    55681 attaacaatt aatgacatgg ctagtataag tggaggaaac gctccaggag atgctgtaat
    55741 tggtggtctt ggaggcttag cttctggatt gaaattttgt aaactgctac atccagtatt
    55801 ggcaggtgga tgtgttgtag gatttacagt tggtggagca tatttgggat atacagcaaa
    55861 ttaaatgatc tatacgattt ttattattat gaatgcgtct ataatgtttt taatcattgt
    55921 tgatgccatt cataaaaaaa tgttgataaa tctataccat atttagtgtt tttaattttc
    55981 aatcaattat ccctttcaga aaaatcggta aacatgttat ctatcgtagc tttggtagcg
    56041 tcattatttg tttttatcga taaaagaaaa tagtgattat gccaatgaat ttagatatca
    56101 ctcttagctt tttaaaatac aaaagagtga aattaaaatg aaaaagactt caaaaatatg
    56161 gaagtgctaa aaaatggtct ggctatcata aatggaggcg gaaaagacgg agcaaatatc
    56221 tttttgacag ggatggcagg tgctgcgcag ggagtgacag tttgtgctca gacaggcgta
    56281 tttatccctt ggcaaggtta tattttgtgt ggagcagctg gtgctgctac aaatattatc
    56341 tggcctcact aaatatataa atgactatct atcactgatg tataagtagt agaggagtgg
    56401 tatgaaaact ttagatatta tttttaatct atctgataga aagatgatat ttctagaaaa
    56461 tgttgaaaag ctgggaggtt acattgtccc ttttaccctt atcatcttga gtgtagccta
    56521 caactttagg cacccttatc ctatttgggc tgctgtacta ggaggtatat cccttattgt
    56581 gatctttatt tattttatac ttattgttta tctatatttg cgttatagat acttggtgtg
    56641 gaaaaaaata ccagaaatta agattaattc tactgagcta tcatgcaatc acatttaagg
    56701 ggaaa
//
LOCUS       DAUGUF010000008        54307 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUGUF010000008 DAUGUF010000000
VERSION     DAUGUF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54307
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.008"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(105..506)
                     /locus_tag="VIB71_000478"
                     /pseudo
     CDS             complement(105..506)
                     /locus_tag="VIB71_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(929..1462)
                     /locus_tag="VIB71_000479"
     CDS             complement(929..1462)
                     /locus_tag="VIB71_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEQ8822236.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1542..2318)
                     /gene="recX"
                     /locus_tag="VIB71_000480"
     CDS             complement(1542..2318)
                     /gene="recX"
                     /locus_tag="VIB71_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEQ8822237.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIPDIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIENLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2433..3788
                     /gene="rlmD"
                     /locus_tag="VIB71_000481"
     CDS             2433..3788
                     /gene="rlmD"
                     /locus_tag="VIB71_000481"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8822238.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITSVKRNFAEAKLLMVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLARFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            4452..5807
                     /gene="rocA"
                     /locus_tag="VIB71_000482"
     CDS             4452..5807
                     /gene="rocA"
                     /locus_tag="VIB71_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEQ8822239.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLEVVDFTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQDDSQSVFAIPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(5908..8613)
                     /locus_tag="VIB71_000483"
     CDS             complement(5908..8613)
                     /locus_tag="VIB71_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEQ8822240.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTNP
                     NFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDKWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDDSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKTYHFGQRFPKEVYQEAQEYLAGLSQ
                     SFQIIDTSGQVSPEAEILGTSIAFDYDLPERSFREPYFAIKVRLRLPITLPAMSWKTL
                     ALKLGNETTPSETDSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPTHDQPFYADQGVTHISVRSNTIQVAELEIQQTFTIPVSADDRLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(8628..9914)
                     /locus_tag="VIB71_000484"
     CDS             complement(8628..9914)
                     /locus_tag="VIB71_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEQ8822241.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQIKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANEKGHQTDHTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPIATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTIFSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            10047..11087
                     /locus_tag="VIB71_000485"
     CDS             10047..11087
                     /locus_tag="VIB71_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8822242.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPAVVADNKGGAYQLTQHLIEQGCDQIWFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDLYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            11138..12832
                     /locus_tag="VIB71_000486"
     CDS             11138..12832
                     /locus_tag="VIB71_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEQ8822243.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDTPLTCRFIGHFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFPMRGIIEGFYGTPWTREERIDCLRFIGNKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQPDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVAELVECVNTLRKLDKPAFQQAIAPWFERVAKDQVFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            12857..14299
                     /locus_tag="VIB71_000487"
     CDS             12857..14299
                     /locus_tag="VIB71_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8822244.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFQEFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRQGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDPYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEERYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIETGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(14910..15788)
                     /locus_tag="VIB71_000488"
     CDS             complement(14910..15788)
                     /locus_tag="VIB71_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ8822245.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAVSAPGAVNKEKGIIEGASAIPYIHHFKIQEVLEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDHLAIKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            15984..16934
                     /locus_tag="VIB71_000489"
     CDS             15984..16934
                     /locus_tag="VIB71_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8822246.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            16944..17870
                     /locus_tag="VIB71_000490"
     CDS             16944..17870
                     /locus_tag="VIB71_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ8822247.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            17951..19396
                     /locus_tag="VIB71_000491"
     CDS             17951..19396
                     /locus_tag="VIB71_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8822248.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            19702..20307
                     /locus_tag="VIB71_000492"
     CDS             19702..20307
                     /locus_tag="VIB71_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEQ8822249.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTSQEENHYSLKSAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEISLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     ILVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            20297..22021
                     /locus_tag="VIB71_000493"
     CDS             20297..22021
                     /locus_tag="VIB71_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8822250.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVHGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRNDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            22021..23505
                     /locus_tag="VIB71_000494"
     CDS             22021..23505
                     /locus_tag="VIB71_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8822251.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDCLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALIGFTVLYLDCQEWQAAIDAYFEQEGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            23435..26941
                     /locus_tag="VIB71_000495"
     CDS             23435..26941
                     /locus_tag="VIB71_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEQ8822252.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNIKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQAPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQPIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFTANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWLLYGSET
                     VSAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWVQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSQGELVSHAQDWLKVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKASTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWCLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLATSQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVI
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            27079..27957
                     /locus_tag="VIB71_000496"
     CDS             27079..27957
                     /locus_tag="VIB71_000496"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8822253.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            28192..28947
                     /locus_tag="VIB71_000497"
     CDS             28192..28947
                     /locus_tag="VIB71_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEQ8822254.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            29000..29338
                     /locus_tag="VIB71_000498"
     CDS             29000..29338
                     /locus_tag="VIB71_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8822255.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEV"
     gene            29340..29645
                     /locus_tag="VIB71_000499"
     CDS             29340..29645
                     /locus_tag="VIB71_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ8822256.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPKDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(30081..31154)
                     /locus_tag="VIB71_000500"
     CDS             complement(30081..31154)
                     /locus_tag="VIB71_000500"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEQ8822257.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQTKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKSLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKQIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(31210..31962)
                     /locus_tag="VIB71_000501"
     CDS             complement(31210..31962)
                     /locus_tag="VIB71_000501"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEQ8822258.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(32202..32272)
                     /locus_tag="VIB71_000502"
     tRNA            complement(32202..32272)
                     /locus_tag="VIB71_000502"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32238..32240),aa:Thr,seq:ggt)
     gene            32439..32693
                     /locus_tag="VIB71_000503"
     CDS             32439..32693
                     /locus_tag="VIB71_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEQ8822259.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            32714..33109
                     /locus_tag="VIB71_000504"
     CDS             32714..33109
                     /locus_tag="VIB71_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEQ8822260.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            33394..33713
                     /locus_tag="VIB71_000505"
                     /pseudo
     CDS             33394..33713
                     /locus_tag="VIB71_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            33710..34273
                     /locus_tag="VIB71_000506"
     CDS             33710..34273
                     /locus_tag="VIB71_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8822261.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTQLTAAETAQLIIQKMTHIKEN"
     gene            34275..36923
                     /locus_tag="VIB71_000507"
     CDS             34275..36923
                     /locus_tag="VIB71_000507"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEQ8822262.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELVRLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            37077..39485
                     /locus_tag="VIB71_000508"
     CDS             37077..39485
                     /locus_tag="VIB71_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEQ8822263.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLS
                     AEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSA
                     SFYF"
     gene            39618..40346
                     /gene="cas5c"
                     /locus_tag="VIB71_000509"
     CDS             39618..40346
                     /gene="cas5c"
                     /locus_tag="VIB71_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEQ8822264.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLLDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            40346..42241
                     /gene="cas8c"
                     /locus_tag="VIB71_000510"
     CDS             40346..42241
                     /gene="cas8c"
                     /locus_tag="VIB71_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEQ8822265.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMGKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            42246..43094
                     /gene="cas7c"
                     /locus_tag="VIB71_000511"
     CDS             42246..43094
                     /gene="cas7c"
                     /locus_tag="VIB71_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEQ8822266.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTVFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYNQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTL
                     EILEGL"
     gene            43096..43770
                     /gene="cas4"
                     /locus_tag="VIB71_000512"
     CDS             43096..43770
                     /gene="cas4"
                     /locus_tag="VIB71_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEQ8822267.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            43767..44792
                     /gene="cas1c"
                     /locus_tag="VIB71_000513"
     CDS             43767..44792
                     /gene="cas1c"
                     /locus_tag="VIB71_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8822268.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            44803..45096
                     /gene="cas2"
                     /locus_tag="VIB71_000514"
     CDS             44803..45096
                     /gene="cas2"
                     /locus_tag="VIB71_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8822269.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   45245..45676
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45245..45276
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaat"
     gene            45836..46546
                     /gene="ccdA2"
                     /locus_tag="VIB71_000515"
     CDS             45836..46546
                     /gene="ccdA2"
                     /locus_tag="VIB71_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEQ8822270.1"
                     /translation="MILSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            46559..47182
                     /locus_tag="VIB71_000516"
     CDS             46559..47182
                     /locus_tag="VIB71_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEQ8822271.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            47225..48331
                     /gene="msrB"
                     /locus_tag="VIB71_000517"
     CDS             47225..48331
                     /gene="msrB"
                     /locus_tag="VIB71_000517"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8822272.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGTYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVIRYKEDKSFNMTRTEVRSRSGDSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            48419..49159
                     /locus_tag="VIB71_000518"
     CDS             48419..49159
                     /locus_tag="VIB71_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8822273.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQSHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            49156..50889
                     /locus_tag="VIB71_000519"
     CDS             49156..50889
                     /locus_tag="VIB71_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8822274.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVPTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMH
                     ELMADDTQENE"
     gene            50962..52041
                     /locus_tag="VIB71_000520"
     CDS             50962..52041
                     /locus_tag="VIB71_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEQ8822275.1"
                     /translation="MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYM
                     TAPVKSIRYACQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYLKENN"
     gene            52064..52780
                     /locus_tag="VIB71_000521"
     CDS             52064..52780
                     /locus_tag="VIB71_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEQ8822276.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELVKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTTTDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(52946..53419)
                     /locus_tag="VIB71_000522"
     CDS             complement(52946..53419)
                     /locus_tag="VIB71_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8822277.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            53561..54241
                     /locus_tag="VIB71_000523"
     CDS             53561..54241
                     /locus_tag="VIB71_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ8822278.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEEYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
BASE COUNT        16343 a         9946 c        11784 g        16234 t
ORIGIN      
        1 ttacaaatcc cattataaaa gaaattgttt aattaatgga tagtaggatg gtatggagat
       61 cttaatgtgg ttttaatggt aattttagca gttatagtaa gacaaaaagt gacttggaaa
      121 agcttataca gacgattctt aactcccaca atatcttctg tcagatttta ttagacttct
      181 tcttggacat gagttggttt acgttttagt acaaattgag attgagctag tgtttcagtg
      241 tcaattttgt atgatttacg aacgtgcagg ctattcaatt gcttcttagc ttctaaagga
      301 ttaaaccgca ttatctgcga aaaaacctga agacgacgag aatagacatt aatcgcttta
      361 aggataatct cagggttatg gacggttttc aagtttccaa gaagacgatt gaggccgatg
      421 gtatcgtttt gtcttgaatg attccttatt ttagtggttt cattttcaat acacgacgtc
      481 aagcgtccta catactttga taaaattcta cctaaaagag gtgtcttgtc agttttgatt
      541 acaacatcaa gtgccaaaag actttgcgac ttaacaagac acttctactt taacgcaaag
      601 aaaaagtagt gagtactctc ttccgtcgga gatttcctcg ctactaaact tagtattttt
      661 tgatactttc cttaggtagt gcttaaggca gcgacttcct ttggaattcc atgccttatt
      721 tttgagatcc taggctcaaa aataccaagt ggcgtcaatg ttagtgttga cgccactttt
      781 accacaacga aaaacatctg ttttggctca ctccacacgc agaaatagga aattggatgt
      841 caaatcagca gagagctgtt catgcttttt gagcctaaaa ctgagtttgt ctgcgttctg
      901 agcactcctt gggagtgctg gacaactctt aacgattctt cagttcaaga taacgtttgt
      961 accaaatagt gatataggcc ttggaaaatg gtcctttttc atgattaatc caatcaacca
     1021 atattttgac attttctttt aggataaagt ccatatcggc tgaatactgc atctcttttt
     1081 tatgaatctc gtattcatca acatcaagta atctcttttc accatccgca aagactttga
     1141 catctaaatc gtaatcaatg tatttgaggg cctcagtgtc catcatatat ggactagcta
     1201 agttacagta ataagagacg ccattatctc gaatcatggc tataatgtta aaccagtatt
     1261 ttttatgaaa gtaaacgatt gcaggttcgc gggtcaccca tcgtctaccg tcactttctg
     1321 tgacaagagt gtgatcatta actccaatga gggcattttc agttgttttt agtaccatag
     1381 tatcgcgcca agtacggtgc aaactaccat catgcttata actttgaatt gtaataaagt
     1441 cgccttcttt aggtaatttc atgccttacc aactttctac aattaaactt atcctctata
     1501 gtctatcata aatgtgtgaa aaaatcactt cttttgtcag tctataaata atttcttaac
     1561 ttgcaattaa tatcgtcgct gttgtagcct tttcggtaga gagcctgata gagcttttgc
     1621 tttaaagtat aaccatcata tttgcgactg agtttacgat attgtttgtc taattctttg
     1681 tcaagaagat tttctatttc ttgattatct tggtcaaaat taaggtgatt gaggctatgt
     1741 ttagctagat cgtatgaaaa gcctttggtc agtaatgctt gggtgatttt atctttcaag
     1801 gcttttggtg gcaatttttc ttgatatttg tcaaagagtt tttggcttac tttttgagcg
     1861 agttggctaa agtcagtttg agataagata ggatcaatgt catgacttgc aatgcctttt
     1921 tgtaataatt tttgttttaa tacttgggga cctttatcac catttaactg attttggcga
     1981 atgtaggtat cagccaattt ggtgtcgtct atccattgtt cttcttggag ttgagtgatg
     2041 atgtcaggaa taatgtgttc ttcaatctca tgcttgcgca ggtaatcagc aacttgcttg
     2101 ttgctgcgtt gttgaaagga aagaaaataa agggctaaat ttttgccgta ggacagttgg
     2161 gcaaaatgtt tcatgtcttc aagctgatca ttgtcaagga ctttatcttt actcaacata
     2221 aaccgaacaa tagtatcttc tgttacataa agggattcgt cattatccaa ttcgataagg
     2281 tagaggcgtt ttttcttttc aattttagtg attttcatac tttgattata tcaaaaatgg
     2341 taaaatagaa gacgaaaata ctgctaaaaa tgtgttgctt gtgaatgctt ttggtggtga
     2401 gattaggata ttagaggaag taaggggaag agatggtcgt aaaggttaaa cagaaaattc
     2461 ctttaaaaat taagcgaatg ggaattaacg gtgaggggat tggtttttat cagaaaactt
     2521 tggtatttgt ccctggtgct ttaaagggag aagatatttt ttgccaaatc acgtcggtta
     2581 aacggaattt tgcagaggcc aaactgttga tggtaaacaa ggcttctaag aatcgtgtca
     2641 aaccagcttg ttctgtttat gaaacttgtg gtggttgcca aatcatgcat ctagcctatc
     2701 ctaaacagct agatttcaaa gatgatgtga ttaggcaggc ccttaaaaag ttcaaaccaa
     2761 ctggctatga acaatttgag attagaccga ctttaggaat gaaaaagcca gatcactatc
     2821 gagccaaatt gcagtttcag ctgcggtcat ttggcgggac ggtcaaggct ggtttatttt
     2881 cccagggaag tcatcgcttg gttcctattg acaattgctt ggtacaggat caactaacgc
     2941 aagatattat caataagatt acgcagttag tggacaagta caagttgccc atttacaatg
     3001 agcgaaagat tgctgggatt cggacgataa tggttcgtaa ggcacaggct agtgatcagg
     3061 tacagattat tgttgtgagt agcaaagaag ttaggttagc gaggttcatt ggcgaattga
     3121 ctaaggcatt tcctcaggtt aaaacggttg ccttgaatag taatcgttct aaatcgagtg
     3181 agatttatgg ggacgaaacg gaaattctat ggggacaaga ggcgattcat gaagaagttt
     3241 tagactatgg atttgcgtta tcaccgagag ctttttacca acttaatcca cagcagacag
     3301 aagttttgta tggtgaggtg gtgaaggcct tggatgtagg gagcaaagat catattattg
     3361 atgcctattg tggggttggc tcgattggct ttgcttttgc agggaaggtc aagtctgtgc
     3421 gggggatgga tattatccca gaagcgattg aggatgcaca aaaaaatgcc aaagccatgg
     3481 gctttgataa cgcttactat gaggcaggga aggcagagga tattattcct aaatggtata
     3541 aacaaggtta ccgcgcggat gccatcattg tggacccacc aagaactggt ttagatgata
     3601 aattattaaa aacgattctt cattaccagc ctaaacagat ggtttatgtg tcttgtaata
     3661 cctccacttt ggcccgcgat ttggtgcagc taacaaaggt ttatgatgtt cactatatcc
     3721 aaagtgtaga catgttcccc catacagcta ggaccgaggc tgtcgtgaag ttacaaaaac
     3781 gtgtatgatt gagtggcaat aacaactcaa gttttataag ctcaggtaat gggtttgagc
     3841 aatagcttga catagtaggg atgtcaaaaa cggtttacta agcatagtca tattattgat
     3901 aactctatgt ttattttaga aacattcatg gttaaaaaag tttgttagtt tgtcactaag
     3961 tagggtctat ttgaagagca agtacacaca gacaatatta ggggaattga ttgttaaaaa
     4021 aagctgtttt ttgctataaa ttagaaaact gagtggtcag gaggttacat taccagaagt
     4081 tattttagta tgctaatatg aacgatgata tagaggattt atcctgattt aatcttttaa
     4141 gctgtaagaa acctttgcaa aaactgtagg ctgtgtgagt ctttatgtgt tagatattaa
     4201 agataaatgc aacacttttt tataatgaga tcaacaactg ataaatctga gttgataacc
     4261 agtaaaatga tcggaatgta gaaaagttac ttaatcaagc ttttcgtaat ttaactgtta
     4321 gaatgacaga acttatgata aaataaagaa tatgattaaa atgaaaaagc tcagtttatc
     4381 tattacggag ttcgaaatga aaagaaaatc gagatgtgat aacatatttt gaacgagaag
     4441 gagaaggata aatgttagaa gattttcttc aatttttagg atttatattt ttagatatta
     4501 ttgaaattat gttaacgtta aagcttttta gctttgtaag tgcaattccg cttcgcctga
     4561 aaaatatttt ttatttatca cttagtatgg ttttgtttca agtagttttt tgggctttct
     4621 ttccagacca tttcatcctt gatgttgtga tgttggctca gtttcttttc tttgcgctta
     4681 tagccctata ctatggtaaa tcaataaaag ctaagttttt aatgttttat gccttttttc
     4741 cactagtgtc tattagtttg gttaagcgat ttattgtatt ttttgttatg ccattgtttg
     4801 gtatgcctta ttcagttgtt aaacataata cactactgat ttacagcatt acttgcttta
     4861 gtattttttt gatttatcgc tgcattcaag tttttcattt cgatttttca acctggcgcc
     4921 aatattttca atcacataga gctagtaaac tattagtgtt tactaactct tcgatggctc
     4981 tatattactt gtgtgtccaa gggatagatg tgatgtcgcc ttctttatca ggacttgcta
     5041 caacgactgc tcgttcaatc atagtgctct tttatttcat tttgtttctt actttattaa
     5101 ttcatttaga gcgttatgta aaacaaaact ctattgaggc aattgtgcaa caaaaagaat
     5161 atcgtgagct gattaattat agtcagcacc ttggattgct gtatcaagat attcaagagc
     5221 ttaggcagct attaactacc gtgtccagtc gtcttaagat tggaatcgaa caaaatgata
     5281 tctctattgt gagacttact tatgaaggta tcttgaatgc tgaaaagaat aatgctaaag
     5341 atgacagact tgatttaact tgtttagata aattacaagt tgaagcaatc agacatattg
     5401 ttttagctaa attaattgag gcaaaaaata agaagcttaa ggttgaggta tcgatcccta
     5461 attgtattgc aacgtttttt ctagaagtag tagatttcac taagctattg tcatttttgt
     5521 tagataatgc tatagaaatg agtttggaga caaagcaacc ttgcttatca atagcatttc
     5581 tggatcaaaa ccataaactt gtcatagtca ttcaaagcag tactaaacaa ggacaagatg
     5641 atagtcaaag cgtgtttgct ataccggctt tgaaaaaaag agatgactgg caatttgact
     5701 taaggaatgt cacgaccatt ttaaatcgtt atgactatct cacaattagc tcgcagattc
     5761 atgatggcat tttaacccag ttaatagaaa tagctaagcc tgactgatgt taaaggtatg
     5821 aataatcact caaaatcaac ttaagagtct gagacaatag tcccagactc tttttgaata
     5881 tgttaatcta ttactaatga taatagttta ttgtttcttc caagctagag ttaaaatttc
     5941 cgctttgcca agttggctgg gtgtgctttg cttgctgtct ttttctaaca aattagtgac
     6001 cttggcattg tagtttggca ggcttaggct aaagtcacaa gttttatcgt ttgagagatt
     6061 atagctgcgc gtgataaggg cattgtctgc taagcgacgt ttgaaagctg tgagggcaac
     6121 ttggtcgttt gtacccgtca aatagctata ttctgcggct aatgttccct cgtgttggtt
     6181 tgtttgtgtg gtaataacag ggacttggcc ttcttgagct cgccagtagc tggcaaattg
     6241 tgtttgctta gtgatgcttt caaaactata agaaaggctg tgcttgccga ggcattgggc
     6301 ttcaggagta gggaaatacc cccagtcgcc catttcgcca acagaacgta agagagtgat
     6361 ggcaatggtg ttggtatctg gtaagatctc atattcgttg aggccatagt taccaatagt
     6421 gactccattt tcaccatcaa agagactcac aaagcattct tggtgctgtg ggttacttgg
     6481 attcttccaa aaggtggcat ctggatgatt tggacgtttg acagtttcaa aaatactgtc
     6541 agctagatga tggtctgttt taaggtgcgt tgggaatagg acgcgcaagc gatgatttgt
     6601 catttggtta tcaaaacgtg tggtaaattg gaggcgagga ttgtttttct ccatacggat
     6661 aagggttgtt aaggttagct cagccttttc ttgtgaacgt cttgcttggc gttctgtgat
     6721 gtcaatgaca gcttccatct cagcctgtaa gcggtcatcg gcggagacag gaatggtaaa
     6781 ggtttgctgg atttcaagtt cagcaacttg aatagtgttg ctgcgaacag aaatatgagt
     6841 tacgccttgg tccgcataga aaggttggtc atgagttggt tggcgagaaa tatattcatt
     6901 tccaatatcg ccacaatctt caaaccgcaa caggtcttga tagattagtc cagattgttt
     6961 atcggtgatg gttagacggc catcggtttg tatcataact tttagaaacc cattttcaag
     7021 gcactgatta ctgtcatcgt agagggaatc ggtttctgaa ggagttgttt catttcctag
     7081 ctttaatgct aaggttttcc aagacatggc tgggagagtt attggtagcc gtaatctcac
     7141 tttgatggcg aaataaggtt cgcggaagga tctctcgggc aaatcgtagt caaaagcgat
     7201 gcttgtgcct aaaatttctg cttcgggact cacttgtcca ctagtgtcaa taatttggaa
     7261 agattgggag agtcctgcca aatattcttg agcttcttgg taaacctctt taggaaagcg
     7321 ttgaccaaaa tgatatgttt tccaggtcag gctgagctca gcaacacttg ttttggaatg
     7381 accgctggta ttaaataaga cgaagggttg gctatccatt ggaaaatccc tggtatcaat
     7441 ggcgtcagca atttgcttag cagcttcttt tgctaaatag tgtccgactt cataggcttt
     7501 ttcaaagcgc gtcatcattt cccgatgaac gctatcaaca ctacaaccac agatagaatc
     7561 atgagggtga ttttgcatga gggttttcca agcgtaacgc agttggtcgt gagggtaggt
     7621 acttgtcacc tcataagcca ttgctgctaa gggttcggtg atgttttcga gttggcgaga
     7681 gactctggta ttagcctgtt tgaggtaaat acgagcagaa gccgtgttag ctagggtata
     7741 ccagccatcg gtttcttgac tggtaatctc tccttggacg gttgaaaggt tctctggtaa
     7801 atcatctgcg agatcagcca agtaatcttc aaagcaggaa tgcacaaatt cgtagtcagg
     7861 atagagttgg ttggctaagg cgattgcctt ggtgacatca agttgtacgg gttgatgatc
     7921 acacccgttc atcatcagaa ggtgcttggt tgaggcgaag cgttcggcgt cagcaagttt
     7981 tttatcccaa aaaagacgcg cctcagcttc tgttgtcggg atctcattgc cattgctgta
     8041 ccagttggcg aagaggagtc caagaatacg actgtcatct ggtccttgcc aactgatttc
     8101 agagaattgg gagctgtatt tttcactggt atctacttga ttgttaaatc cagttggacg
     8161 aatgccacga ccaaaggcag cagcttgtag gccggctttt aacatcagct gtggtgtttg
     8221 tcccatattt ccaaaggtat ctggaaaata accaagtggc acactagcgc cccatttgtc
     8281 acaatcctcc ttgccaatga gcatattgcg cacattggac tcgctgctgg tcaaaaaatc
     8341 gtcctgtaag atatagaaag gtccgatacg gagttttccc gaagcaatgg cttgtctaat
     8401 ctcaggttct cgttcggggc gtacttttaa ataatcatct aggataatgg tttgaccatc
     8461 caaatgaaaa ctatgaaaat taggatttgt ttgaaaaact tctaacaggt catctattaa
     8521 gttaatcaga cgcatgtggt gttgctcgta agccatgtac cactcgcgat cccagtgact
     8581 gtgtgaaata atatgtactt ttttggttgc catagtggcc tcactttcta aggagcaatg
     8641 ctaaagccaa gatagtcaag aagtagttca cagaacatca tgttagccca agagaaccac
     8701 tcacgggtgt attgataagg atcattgaca tcgaaaccct cgtgcattaa gtgggtacca
     8761 gcatctgttg ccacaagcaa atcaagcatc tcttttttac tgtcttggtc aagagcggtc
     8821 aatccttgta aggcaagggc gatatgccag atataatttt ctggtgtatg ggaagaaccg
     8881 atgcctgctg ctgcatttcc ctgataataa taagggtttt cttggctgaa aatggtgcgg
     8941 cgcgttgcca gatagatagg gtcatcttta gcacaaaaac caaggtaagg tgcagcgagg
     9001 aggcttggaa tattagcatc atccatgatg gaaaactgtc ccagaccatc cacttcataa
     9061 gcgtaaatgg tttctccctt gctgttttga acaagggcat ggtctgcaat acctgattga
     9121 atagcttctt ttagctgctt ggcacgagta gctattggtt cattgtgaaa aaggttgtta
     9181 tataaatctt ctagatagga aagcacaacc actgcaaaca tatttgaagg aatgaggtaa
     9241 ccatattgac aagcatcatc acttggtcta aagcctgacc aggtcattcc tgttggtgcg
     9301 acaggacttc cttttccagc atgtgttaag gtatcttctt tgcgccaagt atcgcgttca
     9361 aacaagtaag gagactgggc gtggtcttgc tcaactgtcc ataggtcaag aatgagttct
     9421 accccacgat gaaaatcgtc attaaactga tcggtgcttc ctgtttcacg atagagcaga
     9481 taagccagtt gaatagggta gcaaagggaa tcaatctcat atttgcgttc ccaaatccaa
     9541 gggttcattt gggtatgatc tgtttggtgt cctttttcgt tagcttcttc gttgaaggca
     9601 ttggcatagg gatcgataca aatgtagcgg aattggcgtt tgaccagacc ggcaataatc
     9661 tttctaattt cttcatcttc cttggcgagg aagaggtaag gttttatttg cgcagtggaa
     9721 tcacgtaacc acatggcagg aatatcgcca gttaaaagaa agctagtgcc atcttcgtag
     9781 gtttttaggg ttgtctctaa ggtattggta aagctggttt tgaaattaag agcccaatca
     9841 gggtgttggt ctccacaaag gctttccacc ttggccataa attggctgac gctagttggg
     9901 attggtcttg tcatgtcata tcctccaaaa tgatatatca tttatcttcg gtttcattat
     9961 aaatgataag ttaaactttg tctataagtt tttgaaaagg tttacaactc ttttttgaca
    10021 tgttatactg ataacaggag taaagaatga caaaattatt atacaaaaag atatatcatt
    10081 tcattaaaga gcagatagca tcaggtcgtt tgcaaattgg tgaccgccta cctactgaaa
    10141 aagaattgtc agaacagttc tcggttagcc gtattacttc taagcgagcg cttgtagaac
    10201 tggagcaaga aggcttgatt acgagaagtc gtgggaaagg aagcttcgta gctaaaaagc
    10261 aagtgacgtc ccctgaagcg aataaggatt tattgttgat tcttcctttt gcctcagatt
    10321 atgaattggg ggattatgct aagggaatta tgacctccat tgctgaaaca gggtatcggt
    10381 tgatggtgca actggccagt acggtaaggt tagacaccct gtcagactat gctgggatta
    10441 tttattatcc tgaagatgtc aatcacagta ttgatttcct gttttactgc gaccatcatc
    10501 acattccgct agtcttgttg gataaatctc tggacctttt tcagtttccg gctgttgtgg
    10561 cggataataa aggcggtgcc tatcaattga ctcagcactt gattgagcaa ggctgcgacc
    10621 agatttggtt tgtggcaaca ggctcttttg gagaagtatc atccgttaga gaccgttatt
    10681 tgggttactt agcggcaatg gcagaatcgt ctctaaaatc ccattatttt cctaagacag
    10741 agactgaaac aacagatgct tatttggacc gtttggtgaa aaccttatcg gagacgacag
    10801 ccactaaaag ggggcttgtc gtggaaaacg attggttggc tattcagctg attcaaaaaa
    10861 tcacacaggt aggcttatct attcctgatc aagtcgctat tgtaggcttt gataatagtc
    10921 aagcctcccg tttgttgagt cccaaattaa gcacagcagc tcaagatctt taccaaatgg
    10981 ggcaagaagc agctaaagtc ttgttgcaga ttattcatga gccagaccag gcagtggtgt
    11041 cttgccagtt acctgttcaa gtatttatca gagaaagtag tcactaaaaa agatgttact
    11101 agcatgagct ggttagctca ggtaaaggag accagaaatg accatttatc acgccttaaa
    11161 ggattatcaa gaagtcatga caagaggaga ctatcttgtc tttgacacgc cattgacttg
    11221 ccgatttatt ggccattttt tccgttttga aaatcaaaaa gccctgctgg cagaattggc
    11281 aacgtcaaag tattttcagt ggattgaaga aggccaagca gaggtaacga tgaaacactt
    11341 ttttaaccgt cagctggcta aggatgcctt taccctgaag gtttcagaag ataaggaaat
    11401 cattattgaa agccaaaacc ttagaggttt tcgttacgcc caagaagctt tgcttaaagt
    11461 catgaccttc aaaggggata aactttattt gcccattgtt tctgtcaagc acagcccgtc
    11521 atttcctatg cggggaataa ttgaaggctt ttatggaaca ccgtggacac gagaggaacg
    11581 aatcgattgc ctacgtttta ttggaaataa aaggatgaat acttacatgt atgctccgaa
    11641 agatgatgat taccagcgaa aactgtggcg cgatctttat cctgaggatt gggtgactta
    11701 tttcaaagag ctacttgcag tagccaagga agaagggatt gatttttggt atatgattag
    11761 tccgggactt gattttgatt ataccaagga agctgactat cagttgctct atcaaaaatt
    11821 gcaacaactt ctagcgttag gtgtctgtca ttttgggctt ttgctggatg atattgacta
    11881 ccaaattgta gatgctgttg agagacgatt caaaaagact gcctatgccc aggcccactt
    11941 ggcaactgag gttcatcact ttttaaacca acaacatgcg gcgccagaat tggtgatctg
    12001 tccgacagaa tacgacaacc accatgattc tatctatttg caagagctgt cagaaaggat
    12061 tcctaaagaa gtcgcctttt tctggacagg cccaagcacg ctagcgagtc aaatatcgca
    12121 agcagatatt gaaactatgg cagcagtata tcaacggcct atcattattt gggacaatat
    12181 tcctgttaat gattatcaaa aagatccaga acgtctcttt ttaacccctt ttgctaatcg
    12241 ctcgccattt ttatgccagc cagactatca ggtcaagggg attgtttcta accctatgat
    12301 tagttgggaa ttatctaagc tgaccttgac agatatgagc cattatctgt gggatgctaa
    12361 ccgttatcag cctagtcatt cttggctaga aaccttaaca gactatacag aagatactga
    12421 attagcccta gctttacagg catttgcttg gcataatggc aatcgtcatc tgcacaggga
    12481 ccttcctttt gaagtggaag aagctctcct ggctaaggat gtatcaacgt tatcagcttg
    12541 ggtagctgaa ttggtcgaat gtgtcaatac gttgagaaag ctagataagc cagcgtttca
    12601 acaagctatt gctccttggt ttgaacgggt ggcaaaagat caggtgtttt ggcaggctat
    12661 gttaaatcag gagcctcagt tggaaacact ctatgctgac ttacaagaag ataaacaccg
    12721 cattggaagt gacattccaa gtcgttacta tcgcatctac tatcaacagc aagataaact
    12781 aacagctaat caaggtcaag ttacccaagc aagacctgaa gattatgctt agtcatacga
    12841 gctagaaagg aatgatatgt tagcatttcc aaaagagttt tggtggggag gagccacttc
    12901 aggccctcaa agtgaggggc gttttgctaa gcagcaccgc aatctctttg attattggta
    12961 tgaagaggag cctgacttgt tttacgatta cgtgggacct gatacggctt cggatgccta
    13021 tcatcagatt gaatctgatt tgaccttgtt agcttcacta ggtcacaatt cctaccgcac
    13081 ctccattcag tggacacgtt tgattgatga ttttgagcaa gcgacgatta atcctgatgg
    13141 ccttgcttat tataatcgag tgattgatgc ttgcttggcc aatggtatcc gtcctgttat
    13201 taatttgcat cattttgacc tgccaattgc cctctatcaa gcctatggtg gctgggaatc
    13261 aaagcatgtt gtggacttat ttgtggcctt tagtaaggtt tgttttcaag aattcggtga
    13321 tcgggttaag gattggtttg tccacaatga acctatggtc gttgtggaag gctcttattt
    13381 aatgcaattt cattaccctg ctatcgtgga tgggaaaaaa gcagtccagg tcgcctataa
    13441 cctagcccta gccacagcca aggttattca agcttacagg caaggtccag cagaacttag
    13501 tgatgggcgt attggaacca ttctcaatct gacgccagcc tacccagcta gtcaatcaga
    13561 agcggacatg gctgctgcgc attttgcaga actttggaac aatgacttgt ttatggaagc
    13621 tgctgttcat gggaaattcc cagaagaatt ggttgcggta ttgaaaaaag atggggtttt
    13681 gtggcaatca acgccagaag aattggctct tattgctgag aatagagtgg attatttggg
    13741 attgaatttt taccacccta agcgcgtgaa ggctccggat gtcattccag tgattagccc
    13801 atcttggagt cctgaatggt attatgatcc ctacctgatg cctggccgcc gcatgaacgt
    13861 ggataagggg tgggagatct atcctgaggc tgtctatgat attgccatca agatgcgaga
    13921 ccattacgac aatattcctt ggttcttatc tgaaaatggt gtagggattt caggagaaga
    13981 gcgttaccgt gatgaaactg gtcagattca agatgattat cgcatccaat ttttgaaaga
    14041 acatttgacc tacctccaca aaggaataga aacaggctcg aattgttttg gataccatgt
    14101 atggacgcca attgatggct ggtcttggct caatgcctac aaaaaccgct atggccttgt
    14161 ggaaaataat atccataccc aagtgcgacg acctaaagct tcagcttatt ggtttaaaaa
    14221 agtagctact cataaccgct tgatttcatt agaagtaatg gaggagtttg gaggctctgc
    14281 ttctcacctc agtgattgaa cgtgtgaccg tctcctttga gacaagtgaa taatgatgtt
    14341 accaatgatt aaacaagggc ctttttcctc atgttaagag gatcgaggct cttgtatttc
    14401 tttggaaagt gttggtattt gccgaactag atataagcgt tctgtctggt ttggcatcat
    14461 ctatccacct tgggtaattt ggctcttcaa ttctttagag tatcttggct aaggatgctt
    14521 gtttttcatc ttggtatttt aggattttct ttcatatttt tggaccagat aaaagcccct
    14581 catggtttct agtgactgtt tgttatgtca ctgtccacga taaggggact atatgagtga
    14641 gttattaagt gaggctttgc ttattggcga taactagcat agcttctaat agctcgagca
    14701 ttaactgatg accaatgcct ttaacagaag cgtcagcaac aacgacatca acaaagggac
    14761 caggcatcag gctgcgttca tcagcagaga gtcatttagg cagaaagcca gtatcgttgt
    14821 agctaatcag caatcctttt aggatgtctt tgtagatgtc agaggcgatt agggacaata
    14881 ggggataaga gggatttagc ggtccatggt taggcctcct tgtgttcttg gtaaaaatca
    14941 atggcagctc caagaagatt ggcttcgttt ttaaagtgac aaatagctaa ttggggtcta
    15001 aggtcggaga tttcgacggc ttggtagagt ttgtctagtt cagcttcaat cgctgacagt
    15061 agaaagtcag cttgggaaac accacccccg attaaaatca gttgaggatc aaaggcgtgt
    15121 tgaatgttaa aaataccgat ggctaaactt tggagaaaga cctgcctttc tttgattgct
    15181 aggtggtctc cttgttctgc gagggcaagg acagctttgc cagtataatc ttttccgtta
    15241 ttgacgattg cactatagcg cttggccata tttaccactg tccctaactg actaaaggtt
    15301 tggtagcggt cgttcatgat catgaaacca aattcgcccc caaataagtg ggcaccatgg
    15361 taaatcttgc catcaatgac caagcttcct ccaactccag taccaagaac gagcatggct
    15421 aggctactag cgccttttcc tgcccctaag gtagcttcag ctaaggcggc acaattggca
    15481 tcattttcga tagaaatagg gtaatgtagc cgttcttcta agacctcttg tattttaaaa
    15541 tggtgaatgt agggaatagc gctggcacct tcgataatac ctttttcctt gttaaccgct
    15601 ccaggagcac taacggcaat acctgagaaa tggtaagcag agtaacgagc aacttcttgg
    15661 tcgagtaatt ggtaaaactt ttccagacta gagggagtgg gaaagctgct ttgctggctt
    15721 aattggccat tgtgacagag ggcaaattta agggaagtgc ctcctatatc aatacataac
    15781 aagctcatga ggtgttctcc tttattatag tagaatagac gatcatgtct catcttagta
    15841 tgacagattt aaacaacaat gaaaaggctt tctaagtgat tctatacttt gtgttatcat
    15901 acctataatt tgttgctttc aaataatgaa agcgcttgat atactgtaac tataacgtga
    15961 ttaacacaaa gggaggttgg gaaatgacaa gacaaaccaa caaaaagaca tccttttgga
    16021 aaaatgtgat taaataccgg gccttattat taatggtatt accaggtttc atctggttca
    16081 tctttttctt ttatattcca gttttggcca atgtggttgc ttttaaagat tttcattatt
    16141 cagcaggggg ctttatggaa agtttgaaag agagcccttg ggttggtttg gctaacttca
    16201 aatacctctt tgcttccaaa gatgcttggt tgattaccag aaataccatc gcttacaatg
    16261 tgattttctt actctttaat gttttctttg cgattgcttt tgccattatc atgagtgagt
    16321 tacgaaataa gcgaacggtt aaggtctatc acaccatgtc cttattgcct tatttcttat
    16381 catgggtggt tattgaatac tttgtttctg cctttttaaa tacggataaa ggtttcatta
    16441 atcagctcct gactggaagt ggagcagatc caatcaagtg gtattccaat cccacttggt
    16501 ggcccttgat tttactcttt atgagtgtct ggaaagggct aggctacaat agcattatct
    16561 actatgcttc agtcaaaggg atttctgata cttattatga agctgctatg gtggatggtg
    16621 caagcaaatg gcaacaaatt aggaacatca ccattccaca attattgcca atgatgtcta
    16681 tcctattgat cattaatatt ggtaatatct ttaaatctga tttcggactt ttctacgtta
    16741 ttcccaaaaa ttcaggccca ctttatgacg tgaccagtgt gttagatacc tatgtctaca
    16801 atgccttgac tgctacagga gatattggga tggcatcggc agctagcctt tatcagtcag
    16861 tagttgggac cagcatcttg ttagtcacca atgcgattgt tcgtcgcatg gaccctgatg
    16921 cagccttgtt ttaggaggaa aacatggaga aaaagaaaaa agtcgaaaag gttaatgtta
    16981 gaacctttga tcgaaaaacc aatgctatct ttaatattct gattggtctg tttgccatct
    17041 cttgtatcat tccttttatc ttcgtgatta ttatttcctt cactgatgaa agttacttga
    17101 ttaatcatgg gtatagtttt tttccagatg tctggtcaac taaggcttac cagtatattt
    17161 ttcaaggagc catgtcccat agaatcatga ggtcatttgg gatatccgtg tttattacgg
    17221 tggtgggaac ctttattaac acgaccatga catcaaccta tgcttatgcg atttcaagac
    17281 cttatttccc atacagacgt ttttttactg tttatgcact tatcaccatg ctctttgcac
    17341 cagggatggt tgctaattac ttggtggtca gcaatctcct tcatttgaag gatacggttt
    17401 gggctttgat tttaccaatg gctctgggcc catttggcat cttggtcatg agaacgttct
    17461 ttaaaaagac agttccagat agcattattg agtcggctcg tatggatggg gctagtgaat
    17521 ggatgatttt tatgaaaatt gttctccctt tggctgttcc agggattgct accatcagtt
    17581 tattttctgc cttaacttat tggaatgatt ggtttaacgc cttgctttat gtgcaaagtg
    17641 aaaacctcta cccaatgcag tacttactga tgaaaattca gagcaaccta caggccttgg
    17701 cacaaaatgc tggcatgagt gcacaaatgg cagatagctt agcatcgctg ccaaaagaat
    17761 cagttcgtat ggctatcgtg gttattgcaa ccttgccgat tgccttgact tacccattct
    17821 tccaaaagta ctttgtcggt ggtttgacca ttggtggggt gaaggaatag gacttaagga
    17881 actggtcaca agaccagatt ttatctaatc attagtaaca aaagaaaaca ttttttagga
    17941 ggcttcactt atgaaaaagt ggcaaaaaat cgtgtgtgtg actggaactg tgcttgcagc
    18001 gtctagttta gcagcctgcg aaagcaagtc agcatcaaag gatagtgatg tcaaattatt
    18061 gatgtaccaa gttggtgaca aacctgataa cttcgatgaa ttgatgacaa ttgctaacaa
    18121 gcgcatcaaa gaaaaaacag gtgcaacggt tgaccttcaa tacatcggtt ggggggactg
    18181 ggatgataaa atgagcacca tcattgcctc tggtgaaaac tacgacattg cttttgccaa
    18241 taattatgtg gtcaatgcac aaaaaggtgc ttttgctgat ttgacaacgt taatgccaaa
    18301 atacgctaag aaaacgtata aaaacttaga cccagcctat attaaaggaa atactattga
    18361 cggtaaactc tatgccttcc cagtagatgc caacgtttat gcccaacaga tgctttcttt
    18421 caataaagaa ctagtggaca aatatggcct tgacatttca aacattaagt cctatgcaga
    18481 tgctgaaaat gtcttgaaac aattccacga aaaagaacca aatacagcag cttttgctat
    18541 tggtcaagtc tttagtatgt caggtgacta tgactaccca ttaaccaaaa accaaccctt
    18601 tgctgtgaaa attgatgaag gtaagccaac catcattaat cagtatgaag atgagtcctt
    18661 taaaaacaat ctccgcttga tgcacaaatg gtataaagaa ggtttgattc caacagatgc
    18721 agcgaccaat acagaaggtt atccccttga aggaaacact tggtttatgc gtgaagaaac
    18781 ccaaggtcct atggactatg gcgatactat cttgaccaat gctgcaggaa aagacatcgt
    18841 gtctcgtcca ttgactaaac cgctaaaaac cacatcacaa gcacaaatgg caaactttgt
    18901 ggtatcaagc gtatctaaaa acaaagaaaa agcagttgaa gtcctttctc ttcttaatag
    18961 cgatcccgaa ttgttaaatg ggcttgttta tggtgtcgaa ggcaaagctt gggaaaaaat
    19021 tggcgacaag aaaatcaaac tgctcgatgg ctatcaacca aaaatgcaca tgggtgcttg
    19081 gaatactggt aacaataaaa tcctttacac tcaagaatct gttactgacg acatgattgc
    19141 taaacgtgac caatcaatca aggatgctaa agaatctcca atccttggtt tcactgttga
    19201 cacaaaagtt atcaaaacgg aattgtcaaa tatttcaaat gtcatgaacc gatataaagc
    19261 aagtatcaat actggtacag tggatcctga cgaagccctt ccaaaacttc ttgcagacct
    19321 caaaggtgct ggttgggaca aggtgcaaaa agaagttcaa aaacaattgg acgactttgt
    19381 agctaaagac aagtaaggca ttcattttct tgattataag ttgagggctg ggaaatctca
    19441 gctcttttct tctgatgagt ggaaaaaatg gatcatcaaa taagtggaag ttataaaggg
    19501 agaaaaatta atgtaaataa tgttactact cttagtaaag cggtttccaa aagcctataa
    19561 agtgtgctat attagaagag tctaaactat taatcagagt aaaactaata ccagcatctt
    19621 attgggggtg ctaaaactag tctcgtagct gctggtccct gaaaccgcta taagtgttaa
    19681 caagaaaaag aggactatca tatgaatggc attgaaaaaa cctgcttttt aatttggaaa
    19741 atgatccaat tgaccctcat ttttcatctc ttgtccttag ctggactgat tgtatttggg
    19801 gtggggccag cctggcaaac cattgtcacc ctatttttaa aaacatctca agaagaaaac
    19861 cactattctt tgaaaagtgc tgttcaactt tggaaatctt atttcaaaga agctaatcta
    19921 agatttggtc tttttgccct gactttcctt tttttaacct ttaatttgca ttgggcagta
    19981 cagtttccat ccttgttttg gtttaccgtg tctttcttga ttgtaatagc catggtttgg
    20041 ctaaccatga cctatcttta catggttttt tatgcagtga gctatgagat tagcctttgg
    20101 aataatatga aattagcctt tatcagcgtc tttttaagtt tcaaatcctt tttactcatg
    20161 ctgagcgttt tgctgggaat tatcttagtg acttggcaat acaaaggtct ttatctcttt
    20221 ttaaccttcg gagctctagt cttttgcttg gactttgtca ctaaggctaa tcgtcgacta
    20281 gtagatggag tgattgatga gtgttaaaac attgggaagg tatgtgacta accactttaa
    20341 gcagggtttt ttgattaatc gactgatgaa attatatagc ctgctaattg taagtttttt
    20401 cactttagca gctattggct tgagcagtta ttctattagt agtacttata aaagggtgga
    20461 tgctgaggcg cagatgcgac tggaggagac tctaggtaga ttgcagtcac aaaacgatat
    20521 taccctacgg gttttagacc agttggttgg ccgttcagaa gattaccata acctctatca
    20581 atatatgacg ttaaccccaa accaatattt ttcaaacgtt tttgaagact gggaaaaagg
    20641 aaaagacacg gtcctatttt ctgaagaggt gaggcgtctt tttgacttgt accctgatgt
    20701 gacttctatg accctactgc tagaggacag tagtgcttat ctgtacgccg atagggtcat
    20761 taagacgggt cgtttgcttt atagcaagcc tgaaaaagta accggaaatg ttttagttcg
    20821 ctccattcga aatccagaat caggagatgt gacaggtcgt ctttacctga cctttgacaa
    20881 accaccgact ttggtagaga cacagcagga tcactattta gctacttttg cttttgatta
    20941 ctatggccgc aaactcttcc atcaaggagg tcggagattt cctcatttag aggctgaggt
    21001 taaaaaggct atcaaggcag atcgggcagc tgatcttagt aatctcagca aggcttatcg
    21061 gatgcagtac aatcgctcgg gagacctctt agcttatgtg gctgtcagaa aatcctattt
    21121 attagcggaa gctgtcagga cagtttttgt gcatggcctt gtttctctac tcttagcttg
    21181 gctgttattg cagttgctct ttagggtttt ccgaaattat atccagcagg tttctgaaat
    21241 tacggatact gttgaaatgg ttgcagcagg cgatttgtct ttaaccatcg acaacagcca
    21301 catggaattg gaactgtatc atatctcaga agccattaat cagatgttgg ccagcattaa
    21361 agcttatatt gacgaagttt atgtgttaga ggtagagcaa cgagatgccc aaatgagagc
    21421 tctgcagtct caaatcaacc ctcatttttt atacaacacg ttagagtata ttcggatgta
    21481 cgcccttagt tgtcaacaag aagaattagc agatgtcatt tatgcctttg cgagtctgct
    21541 tcgcaacaat attagccaag ataagatgac caccttaaaa gaagaactgg ctttttgtga
    21601 aaaatacatt tacctctacc aaatgcggta tccagatagc ttcgcttatc atgtaaagat
    21661 tgatgagagt attgctgact tagccattcc taaatttgtc attcaacctc tcgttgaaaa
    21721 ttattttgta catgggattg attatagtcg caatgacaat gcactaagca tcaaggcatt
    21781 agatgagacg gatcatctct tgattcaggt gcttgataat ggacgtggta ttagtcaaga
    21841 gcgcttagca gatatggaaa aaaggcttca agagcaccaa acaacaggca atagctctat
    21901 tggtttgcaa aatgtttacc tccgtctttt ccatcatttt cgagacaggg tttcttggtc
    21961 catggctaag gagccaaatg gtggctttat tattcaaatt aggattagaa aggatgcttg
    22021 atgtataagg tactattagt tgacgatgaa tacatgattt tacaagggct caccatgatt
    22081 attgattggc aggcacttgg atttgaagtg gttcaaacag caagatcagg caaggaagcc
    22141 ttagcctatt tgactcagta cccagtggat gtcatgattt cagatgttac catgcctgga
    22201 atgacaggac tggatttaat agaagcagct aaaacctatc atcctcagct acaaaccttg
    22261 attttatctg gttatcaaga attctcctat gtgcaaaagg ctatggaatt agaaaccaag
    22321 gggtatttgc taaaacccgt ggataaggca gaattacagg ctaaaatgaa acaatttaaa
    22381 gactgcttgg atgcccagca ggcagaatca atccggcaag aagcctatca tgacagcctt
    22441 ttgacccttt ggcttacaga tgaattgagt gagaaagaat ttcagcagtt aagtcaaggc
    22501 ttgccagcgg ctgctttaat tggttttaca gtgctgtatt tggactgtca agagtggcaa
    22561 gcagccatcg atgcttattt tgaacaagaa ggtcagcctt tttacctcaa aaaagaagaa
    22621 gataagaagg tttatctggc tgtcctactt ggtaaaactg accaagccaa ggcatttacc
    22681 tatgacctac aaaaacgatt ctcaagaaac atgcatcaac ttattttggg agaaacagtt
    22741 gatgactggg aaaatgttta tgaaagctac aatcaggtgc ttaagagcct cttttacaat
    22801 tgtgaagtgt caccaattag agcaaaagat aagtccaaaa ttgaactacc agagtcccgt
    22861 ttgcagttct ttgcttttaa caaggcgttg atgattgggg acgaacctac aatcttgtct
    22921 aaattagaag ctatttttga cgagatgaag accttgaact tttcaccaga ggatgtgaag
    22981 catgtttcgt tcttgttgtt ttctgacatt taccgtcaat ttcccatttt agataaaatg
    23041 acttatctgt ccatggtaaa aactattcat gacagccaat ccattgatcg cattttgagg
    23101 gaactaaaaa aagtgttgga tgtcaccaat cagaacaatt cccctgaaaa acgctattca
    23161 gatttagtta gtgaaaccat tgattgcatt cgcaaggaat accatcaaga attaaccctt
    23221 aaagctatcg ctgataggtt acatgttaat ggggtttatt tagggcaatg ctttaaaaat
    23281 gaaaccgagc gtagttttac ccagtactta aatcatgtta ggattcaaaa agcgcaacag
    23341 ttattgcttt acaccaacca atccatcaat gaaattgctt atgaaacagg ttacaatacc
    23401 aatcattatt ttatcaagat gtttaaaaag ttgaatggtt tatcgccaaa agagttcaga
    23461 gatcgttaca aggacaatta ccaagccatc aagggcgacc agtaacatta aacaggagat
    23521 tgatatgaca ccagatagca aggagcagac agtgactggc taccaatacc actatattga
    23581 tcaagaagga agaaagcagc cctttaatca aggctggcgt tttcttatgg cagatgtggc
    23641 gtgtgctcag gccccttctt ttgatgattc gaactggcag gtgattcatt taccacatga
    23701 tttcagtctt acgcagcctt acacaagaaa tggtgaagct gaaagtgctt ataaattagg
    23761 tggtgtcggt tggtatcggc attatctcgt gttagatgag gttttagctg gttgtcatgt
    23821 tgccattact tttgagggtt cctatatgga aacggaaatt tatgttaatg ggcaattcat
    23881 tggcaaacac ttaaatggct atcaggaatt tacctatgat atctctgatg tagtgacttt
    23941 tggagctgaa aatcttctgg ctgtccgggt tgaaaacaag gttcccagtt ctcgttggta
    24001 ttcaggcagt ggtctttatc gtgaagtgag tttgtctgtt cttccccagc ttcattttgt
    24061 ggcagaccag gtagcaatga ccttggctga tactgctgtg caggagaaag ggcaacagaa
    24121 agttgattta cgctttgccc ttaatcagcc tattcagact tgccactacc aattgagcct
    24181 ctgtttatgg gaacaatcac attgctcaaa agacaaaaaa ctcctttatc aagaaacaga
    24241 agtgcctcta gctgatttgg ctttccaaag acagtatggt cttacactgt ctttggaaga
    24301 actccaattg tggtcaccag ataatcctca cctctacgat ttagaactca ctctttacta
    24361 tcaaggtcag gtcattgatt gcttttgcct tgaaactggt tttcgtcaac tgacttttac
    24421 ggccaatcag gggctttttg tgaatggcag agctgtcaaa ttaaagggag tttgtttgca
    24481 tcatgaccaa ggaggcctag gagcttgtgc ttacgaagat gccctagcca gacaattagt
    24541 cctgttgaaa gacatggggg ctaataccat tcgtagcacc cataacccaa gtagtcccaa
    24601 acttaggcaa ctagccaatc gtctcggctt ttttgtgatt gaagaagcct ttgacacctg
    24661 gacctatgcc aaaaatggaa acgttaatga cttttcaaac tatttccatc agactatcgg
    24721 aactgaaaat gcaaactatc ttcaaagagt gaggtcacct gaaacgagct gggcccagta
    24781 tagtattgag gccatggtct ggtctgccaa gaatgacccg tcagtgttga tgtggtcgat
    24841 tggtaatgaa ttgatggaag gtttttcagc cgatgtcagt cattacccag agctgacaag
    24901 acaaatgtgc caatggattg ctgctattga cacctcacgt cccattacct ttggggacaa
    24961 taaattaaaa gaagctgact tttgctggca tgaggaagtg tcgcaaatgg caactcttct
    25021 tagtcaatta gaccatcccc agggactcat tgggttaaac tatgctaatg gaaaagacta
    25081 tgataagctt catgaggagc actctgattg gctgttgtat ggttctgaaa cagtttcagc
    25141 cattaccagc agggcttatt ataaagagac aaaaaaagtt cttgactccg gttatcacct
    25201 aacctcttat gatcatgcta aggtcgattg gggtgctttc gctagccagg cttggtatga
    25261 taccattacc cgtgattttg ttgctggcga atgcgtttgg acaggctttg attatttagg
    25321 agaacctaca ccctggaaca agatcgacag cggtgttgta ggcctttggc cttctcctaa
    25381 aaatgcctac tttggcattt tagacacggc aggctttcca aaagatagct attattttta
    25441 ccaaagtcag tgggtgcagg ggcagaccac cttgcacctg ttaccagtct ggcagaagga
    25501 ccagctttgt ttcgatgagc agggattggt ggaggttgtg gtttatagca atgctgccag
    25561 tgtgcaactg atgtttgaag atgagcaggg caacttaaca gattatggaa ggaaggcatt
    25621 tcatacttat agcacgccaa cgggacacac ttatcagctt taccaaggag ctgatgctgc
    25681 taagaatcct cacgagaatc tttacctgac ttggcgagtg ccctatcaaa aagggttgct
    25741 aagggcagtg gcctacgaca tttctggtaa aagcattcca aaaaccagtg gacgttctca
    25801 ggttagaacc tatggttcag tggcaaagct atcttggaaa gcctttgaag cacctattga
    25861 cgctccttgg gaattgcttt atctggattt atcacttttg gatagccaag gtgaattggt
    25921 cagccatgct caagattggc taaaggttca agtagaagga ccagcccgtt tgttggctct
    25981 tgataatggg aatccgactg accacacccc ttatcaggag cctctacgcc aggcatatgg
    26041 cggaaaatta ttagccattt tagccctcac tggagaggcg ggacacatta aggtcacggc
    26101 aaaagcctcg cagcaactta gcagtgtttt tcagacacaa gtagcctgcc gtgcccccaa
    26161 agaacactta gtgacactac ctttagagaa atatcagttt aaaaagagcc gactgacaag
    26221 tcaacaagaa attggtcaat cttgtctaaa gaccacacaa ttcctttctg ttttggagaa
    26281 caaagacacc cagcaaaaag caggtaaggc tagcacacct cacattctta tcactagtta
    26341 ccaacactat ttatctctgc ccttgcaggt ttgttctcag gcatttgatt ttaaaaaagg
    26401 cgatgatatc ttcttgcctc agtggctcca agtcaaagat gcccaaggtt cttttgtgaa
    26461 aaaagctttt ccaatgacat ggtgcctaaa agagaaaatc tttgccaagc ctattcttgt
    26521 cacgggctat gtttcttgtt ttgggcaatc aataccggtt gaggcaaggc ttaacctagc
    26581 acaagctagc aaaagacggc accaggatct cagtttagtc gccaagcaat ccctggccac
    26641 aagtcaaaaa aggctaactt attgctacca atatgatacg gtgcaagcca taggagccat
    26701 tagcttgcaa aatcacacag gcacatctct tagtgtttct gtggcaatca gttatggtag
    26761 tcagagctct attaagcaag aaaccttgat gctagctgat agccacttga gccagttaga
    26821 agaggttatt ttcttcgatg atattttgac tgttttgtat ctggcagtga tccttgaagt
    26881 cattgaagga cctgacctaa ctgaagacag tattcaaatt ggcctttggg atttagcatg
    26941 aagcatgagt aaaagaagac ttctttggca ccaggtctga tgaattctgt aaaataaggt
    27001 ataataaaaa acaaataggc gtcctttatt acgtgaaagg cgcctttaca aggttgaaat
    27061 ggaaagtgag atttctaaat gtcagaacgt ttatcaggcc acaccctgtt ggtctctttg
    27121 cttgctaccc ctattcgtca tagtttgtct cccaaaatgc acaatgaagc ctatgctaaa
    27181 ctggggctgg attatgccta ccttgctttt gaagtaggga cagagcaatt agcagatgcc
    27241 gtgcaaggga ttcgtgcctt aggaattcgt ggctccaatg tgtctatgcc aaataaagaa
    27301 gctattttac ccttattgga tgacttgtcc ccagctgctg agttggtcgg tgcagtcaat
    27361 acggttgtca ataaggatgg taaaggacat ctcgtggggc atattacaga cggcatagga
    27421 gcgctcagag ccttggctga cgaaggagtg tcggtaaaga acaaaatcat taccctagca
    27481 ggagttggtg gggctgggaa ggctatcgct gtccagctcg cttttgacgg cgccaaagag
    27541 gttcgtttgt ttaaccgaca agctacacgt ctaagtagcg ttcaaaagct tgtgacaaaa
    27601 ctgaaccagc taacaaggac taaagtaacc cttcaagact tggaagatca gactgccttt
    27661 aaggaggcca tcagggaatc tcatctattt attgatgcta caagtgtagg aatgaagcct
    27721 ttagaaaatc taagtttgat taccgacccc gagctcattc gcccagactt ggtggtcttt
    27781 gacatcgtgt acagcccagc agaaaccaag ttactagcct ttgcccgtca acatggcgcc
    27841 caaaaagtca ttaatgggct agggatggtg ctttatcaag gagcagaagc ttttaaatta
    27901 atcactggtc aagacatgcc agttgacgct attaaacctc ttttaggtga tgagtaacac
    27961 tttttaagta agcttaatta tgatatatta ataagagatg gagcagtcat catgggctgc
    28021 taaaattcct tttgcgagag ctgtttttaa gagcaaaaag cttatttgaa gagccttatc
    28081 cctaacgtga tacaagtcat agttcctttg aggtctgcca gataacctac cgttttttta
    28141 gaaaagaagc tcttataaaa ggaaaagttc aatgaataaa ggagaatagc aatggtaaca
    28201 aaggaagttg ggcatgactt tttagcacgt ctaggaaaaa aacgcttaag acctggcggt
    28261 gttgaggcga caaactggtt gattgaacaa ggacaattct ctcaggattg tcacgtttta
    28321 gaggttgcct gcaatcgctg cacgacagca atagagttag ccaaaacctt cggttgtcag
    28381 attgatgccg ttgacttaaa ccccaaggtt gtcaaagaag cacaagaaag ggttgctgtt
    28441 gaggggttaa cccgtcacat tacagtatcc caagccaatg ctttatcact accatttcca
    28501 gataaccatt ttgatattgt gattaatgaa gccatgttaa ccatgttgaa cgcccaagcc
    28561 aaggagaagg cactcaatga atattggcgc gtgttaaaac caggcgggcg acttttgaca
    28621 catgacgtag cttatgaaga tccaaaaaca agacaagtac ttgacgagtt acgtcaaacg
    28681 attcatgtca atgttgctcc cttgtcacta acaggttggc aagccttata tcaagaacac
    28741 ggtttttctc aagtgactta tcaccatggg aaaatgtctt tgatgacacc tcgtggaatg
    28801 attaaggatg aaggtcttat gaacaccctg aacattatga gacgaggcct taagaaagag
    28861 aacagacaac agtttttaaa gatgcgtcgt ttttttacca gaacaggcaa aaatctctgc
    28921 tatattgctg taaaaagtgt aaaataaacc ttagaccaac ctgtccatac aactaaacag
    28981 accatagagg agttcgaaga tgtcttatat caataatatt gagcacgcga aggttcttga
    29041 tttgacgcaa gaagtaatga ttgagcaaga tcaaatgtta agtagaacac tagtccaaag
    29101 gcaagactta ggaataacag ttttttcctt agataagggc caagaaattg ggcgacactc
    29161 atcaccagga gatgccatgg ttactatctt aagtggctta gcagaaatca ccattgatca
    29221 agagacctac cgggttgctg aaggtcaaac cattgtgatg ccagctggga ttcctcatgc
    29281 cttatatgca gtagaagcct ttcaaatgct tttagtagta gtaaaaccgg aggtttaaca
    29341 tgattgaaaa tctctctcaa ctggtgcaat atcatgatca tcaggtggct agccgatcct
    29401 tgagccgtct actgggatta tctcaatcta ttgttttata tgccatggcc caaggagaaa
    29461 gcattagtca agagactagt ccaaaagata aagtaatact tgttttagaa ggtcagctca
    29521 ttttcgattt agaggatcaa aaacaggtcc taactcaaga aagtctcata gccatacctg
    29581 cccaaaaagt ccatcattta gaagctaaaa ccgattgtaa actattacaa gtgcttttag
    29641 attaagggct tattgtcaac tgtattgggt ggcctatgga aaagcaaaag agaagatgac
    29701 gctcatcttc tctttttacg tattcaaagc gatgacaata cgaattttaa ggcttggctt
    29761 tctcatctcc agattatgcc ctttagcttg gtttagttta gaattcacta aaaaaacctt
    29821 aatgagtttc ctatctcctt ataggtttct cattaaggct ttttagacga aataattgaa
    29881 cgacaggcaa aagaaagatc tttttacgag tgataccgtt ctcctatagt ttcataaatc
    29941 ctctttttga tgttgctgtt agttattctt agctaaaagt tatattgtta tcaagacttg
    30001 tcttgtagta acatgtttta ggagttccag gataccgtta ttctcttagc aagcttaact
    30061 agctagagtg gagtcactat ttataataaa ctgtcgagct tctcgacaaa ttggtgatcg
    30121 tctttgttaa tggctagggt ggtaaaaccg gtttctgtgg gtaatataaa gataatatgt
    30181 tgctcagaat tcttcttatc tgttttaaag acgtcaaaga gggatgtcgc agagacatca
    30241 gctctttcaa gtgttgttgg taactggtaa cgttcaaaaa cttgaaggag gctatccaag
    30301 tcctcttttg gcaagagtcc tttggaaaca gccagtttag catcaaccac cataccgata
    30361 gcaatggctt caccgtgatg gtaaaaatca tggtggcaga gcgattcaat cgcgtggccc
    30421 aaggtatgcc caaaatttaa agacatgcgc aaaccatttt caaattcatc ttgttcaaca
    30481 atctgttttt tattggaaat ggattggtaa atcagacgtt caagtccctg cttatcggtt
    30541 tctttttgaa aatcacgtaa ctgctgaaaa agcggtctat catgaatgaa gccgattttg
    30601 agcatctcac tgatgccgca ggagaattcc cgttgcggta aggtttccaa aaaggtggtt
    30661 gaaataatga tagcttctgg agggtaaatg ctgccaatca tattggttag acttttaaaa
    30721 tggactccaa ctttgccccc gatactgcta tccacctgac taagtaaagt cgttgggatt
    30781 tgaatgtagg gaataccacg gtaataggtt gcagcgacaa aaccacccag atccccaaca
    30841 acaccaccac caatagtaac aatcatatct tttttggaaa aattttcagc gatgagctga
    30901 tcgtagatag cactgacacg ttccaaagat ttggtttgac ctcccggggg gcagacatgg
    30961 acaaaagcgt tgtattgctg agcaaattct tcaaagagag tctgatacaa gtggtagacc
    31021 gtttgatcgg tgataaacaa gagtttacgc tgcttgcgct caccaaggca atctgctaag
    31081 gtttttaaaa catggtcggt aaacaggata tcataatcct tgacccgaga atggacatga
    31141 agtgtttgtg gcataagcac tcctttcatc agtactaggt aacagagata acgcagtgat
    31201 atttagagct taatcttgcc aaagttcctg ccccaactgt tctaattgct tataatcaat
    31261 ttgctgggca gcatctgaca gcgcatggtc gggatcagga tgaacctcca tcatgatgcc
    31321 attggcaccg acagccttcg ctatcttagc agcaggtaag agtaaatctc gtctgcctgt
    31381 cgaatgagac acgtccacaa taatcggtaa atctgtcttt tgttgaataa tagggactgc
    31441 cataatatca agcatatttc tagtctccac atcgtagcca cgaacgccac gttcgcataa
    31501 gataatgtta gattttccag tgtcttgtaa gtaggaaagg gcgcccaaat attcctcgat
    31561 agtagccatc aagcctcgtt taaacaaaat aggcttatcg atgtgtgaca aggtttttaa
    31621 aaattcaaaa ttttgcatgt tgcgggcacc aacctgaatg acatcgagat agtcataggc
    31681 ttcttctaat tggcgctcgg acatgatttc actgaccgat agtaagccaa attcctgaca
    31741 aacctcatgc aagtaacgaa ttccttgcag gccaaggcct tgaaaagaag cagcagatgt
    31801 tcttggttta taggcgcctc ctctaaaata gttgtaacca agttttttgg cacttgaagc
    31861 tgctaatcta atgtgatcat aagattcaat ggaacaaggt ccaacaataa aattattctt
    31921 agaacaagtc ttattttgaa agtcagacat aatgtcaatc attcgtttga ttcctttact
    31981 aattctgtat ggcgtgctct atgggataac gtcttattta ggaatacaaa atctcgttgt
    32041 tatccatgaa gcacccttag cctgtgaaat gataccataa acaagatgaa atagcaagta
    32101 aaccctagat tgtctatgtt cttagtcatt tttattaaaa aaggcttact agctataaaa
    32161 aatactgccc taaatcttat taggacagta ttttttatag atgccaccac cgagaatcga
    32221 actcggaacg aagcattacc attgctttat tataccattt aactacagcg gctacctttt
    32281 tataatacta taagttatta attgatgcaa gcttttctta aaaatatttc cttaattgtt
    32341 tatcatcaaa atgagagtac cagttattaa taacatggca caagaggcct gccttatggt
    32401 ataatggtaa agatgatttc agaaagagga agctaggcat gtcttatgaa aaagaatttt
    32461 taaaagattt tgaagactgg gttaaaactc agattcaagt caatcagcta gctatggcaa
    32521 ccagtcaaga agttgcccaa gaagatggcg atgaaagggc taaagatgcc tttattcgtt
    32581 atgaaagtaa gttagacgcc tacgaatttt tactaggtaa atttgacaat tataaaaatg
    32641 gtaaagcctt tcacgatatt ccagatgagt tatttggagc aaggcattat taaggacaag
    32701 gagacacgaa atagtggcaa aacaaaaaaa tcgtaaaaaa gcattgaagt tagaaatgaa
    32761 gcgtaatggc ttgttaaaaa aagcaggtca agtttttgat aaggcagttg aaagtgttga
    32821 aacagctgtg gataaaacca tttctgctgg taaaaatctt gtggaaaaag gcagccaaac
    32881 ggttgaaaac ctgacagcaa gcaaggaaag acttactctt gatgagtttg cagggcagcc
    32941 agttgtagct ggtatccgct ctgaccttgt cgaaacccta tatgcagaag gcatccattc
    33001 agcgcaagct tttaaggagt ggacagaaaa agacctcctt gctcttaagg gcattggccc
    33061 agcaacggtt aaaaaattgg tcgaaaatgg cgcaagcttt aaaaaatagt catcttctcg
    33121 ttgcttaatg gctataaatt tgttagaata ttagcaatca gaggtgcatt gagttgatct
    33181 gttacagaga gcggtggtgt tgagaaatcc gcacagatgt caaggctagt agctgaggat
    33241 cagaaatcag atatgaaaag tagcagaccc attttatggt ttgaaacagt ggtggtaccg
    33301 cggaaatcgt aacacgaaat tcgtccctgt ctaggttatc taggcaggga ttatttggtt
    33361 tcatttgaaa gaagatgatg gcttattgtt aaaatgttgt tagaagtata taatagaaaa
    33421 actttgtcca aagtggaaac agaacggctg ctattacgtc aacgaaaagg ggacaaggca
    33481 ttgttccaga agcggcttca gctctgattg aaattggttt taccttactt gatttgcata
    33541 aaattgagct gggttgctac gactacaaca agcaaagtca ggcagtggct cgcaaattag
    33601 gctttacctt agaagccaat gcccgtgacc gtaaggacgt tcaaggtcgc cgctgtggcg
    33661 acatgcgttt tgggttactg agaagtgagt gggaggagca gaaacaaaaa tgaaccttat
    33721 catcattggt gctcaagcgt cgggcaagat gaccattggg caagaagttg ccaggcagac
    33781 aggcatgact ttgtttcata atcacgattc tattgacttt gttttacggt ttatgccttg
    33841 gtctcaagag agcactgcct tgattgaacg tatccgtttt gctttttttg aaacctttgc
    33901 taagacaggt caagacatga tttttactat tgtaattgac ttcaatgatc caaatgatgt
    33961 agcaatgctt gaaaagattc aggctgtttt tcagtcttat gaccaagagg ttctctttgt
    34021 cgaattaaaa acagatatag aggaacgtct taaacgcaat cgcacagaaa atcgtctcaa
    34081 acataaacct cttaaacgca acatcgagtg gtcagaacaa gatattcaat ccacgatggc
    34141 atatgctgtt tttaatccag aagaaccacc caaaacgctc acgcattacc aaaaaatcaa
    34201 taatacccag ctcaccgctg ctgaaacagc gcagcttatt atccaaaaaa tgactcatat
    34261 caaggagaac taagatgaca gaactatcac ctaaatacaa tcctgccgag gttgaggcag
    34321 gtcgctatca aaaatggctt gatgcagatg ttttcaagcc atcaggagac caaaaagcaa
    34381 aaccgtattc tatcgtgatt ccaccgccaa atgtgactgg taagttgcac ttaggacacg
    34441 cctgggacac aacgcttcaa gatattatca ttcgtcaaaa acgcatgcag ggctttgata
    34501 cgctttggtt gccagggatg gaccatgcag ggattgcgac acaggctaaa gtagaggagc
    34561 gtctgcgcga gcaggggatt tctcgttacg accttggtcg tgacaaattc ctagacaagg
    34621 tctgggagtg gaaagacgaa tatgccacta cgattaaaga gcagtggggc aaaatggggc
    34681 tttctgtgga ctacagccgt gagcgcttca cccttgatga gggcttgtca aaagcagttc
    34741 gcaaggtttt tgttgacctc tacaaaaaag gctggattta ccgtggtgaa ttcatcatca
    34801 actgggatcc tgctgccaga actgcccttt ctgacatcga ggttatccac aaggatgttg
    34861 agggagcttt ctatcacatg aactatatgt tggaagatgg ctcacgcgcc cttcaggtgg
    34921 caacaacgcg accagaaacc atgtttggag acgttgccgt tgccgtaaat ccagaagatc
    34981 ctcgttacaa agatttgatt ggcaaaaatg ttattttacc aatcgtgaat aaattgattc
    35041 caatcgtggg tgacgagcat gccgatcctg aatttgggac tggagttgtg aaaatcacgc
    35101 ctgcccatga tcctaacgac ttcgaggttg gtcagcgtca taacttacca caagtcaatg
    35161 tcatgaacga tgacggtacc atgaatgagt tagctggcga ctttgcaggc atggaccgtt
    35221 ttgaagctcg tcaagctacc gttgctaaac ttgaagaact tggcgcccta gtaaacatcg
    35281 aaaaacgtgt tcactcagta ggtcactcag aacgttcagg tgcagtcgtt gagcctcgtc
    35341 tatccaccca atggtttgta aaaatggatg agcttgctaa acaagctatg gacaaccaag
    35401 aaacagatga ccgagtagat ttctacccac cacgctttaa tgataccttc cttcaatgga
    35461 tggaaaatgt ccatgactgg gtaatctcgc gtcagctttg gtgggggcac caaattcctg
    35521 cttggtacaa tgcagaaggt gagatttacg ttggcgaaga agcaccagaa ggtgatggct
    35581 ggactcaaga tgaagatgtt cttgacactt ggttctcatc tgctttatgg ccgttctcaa
    35641 ctatggggtg gcctgacaca gatgtagaag atttcaaacg ttatttccca acctcaacct
    35701 tagtaacagg ttatgacatc attttcttct gggtgtcacg tatgattttc caatcgcttg
    35761 aatttaccgg gcgtcagcca ttccaaaatg tcctgattca cggtcttatt cgtgacgaag
    35821 aaggacgcaa aatgtctaaa tcattgggga acgggattga tcctatggat gtcattgaga
    35881 agtacggtgc cgatagctta cgttggttcc tctcaaacgg ctctgcccca ggacaagacg
    35941 tgcgtttctc atacgaaaaa atggacgcct cttggaattt cattaataaa atttggaaca
    36001 tttctcgcta tatcctcatg aataacgaag ggttgacctt ggaagaagct gaaagtaatg
    36061 tggctaaggt agctgcctca gaagctggaa atgtgactga ccagtggatt ctccacaatc
    36121 tcaatgaaac aatcgctaaa gttacggaaa actttgacaa gtttgagttt ggtgtggcag
    36181 gacacattct ttacaacttt atttgggaag aatttgccaa ctggtatgtg gaattgacca
    36241 aggaagtgct atatagcgac aacgaagctg agaaagttat cacgcgctct gtccttcttt
    36301 atactttgga taagatttta cgtctccttc acccaatcat gccatttgta acagaagaaa
    36361 tttacgctca atatgcccaa ggttctattg tgacggtgga ctatcctgtg gttcgcccag
    36421 cttttgaaaa tgaagctgcg cataaaggtg tggaaagtct gaaagacctg attcgtgcag
    36481 ttcgtaatgc gcgcgctgaa gttaacgtgg caccatcaaa accaatcacc attttggtga
    36541 agacagcaga tagtgagttg gaagacttct tcaccagcaa cgtgaactac atcaaacgtt
    36601 tcaccaatcc tgaaaaatta gaaatcagct cagccattgc tgcgccagag ctggctatga
    36661 ccagcatcat cacaggtgct gaaatctact tgccactagc agatttgctt aacgtggaag
    36721 aagaactcgt tcgcctagat aaagaactag ctaaatggca aaaagaattg gacatggtcg
    36781 gcaaaaaact cggaaacgaa cgctttgtag ccaacgccaa accagaagtc gtccaaaaag
    36841 aaaaagacaa acaagctgac taccaagcta aatacgacgc aacccaagaa cggattgcag
    36901 agatgaagaa aattaaatca tagtgtttag aacgcagttg aaaaactgtg ttcttttctt
    36961 actaatagag atattagatt gaagtttaat tatgagaaaa acgctttctt tatttaaaga
    37021 gttatgttac aatactatta caatcatcgt acaaatagtg ttattttgag gggcatatga
    37081 gaatgatttt agcacactat gactgtaaaa aagataaaaa gcaatcttta gatgagcatt
    37141 tatggcatgt ggcctgttct agtcgacagg aagcatctat aattggtcaa ggagatgtgc
    37201 tttttttaat tggtctttac cacgacctgg gcaaagctga tcgaaccttt caagataaat
    37261 tattaaataa tccaaatcgg catgttgatc actcttatgc aggggcaaaa tacttatgtt
    37321 ctattattgg gcctcatcta aaaaaccgag gggttgataa aaatgagaga atgacattca
    37381 acgaaatggt ggggtatgtc atctctgctc atcatgggat gtatgattta tgctactatt
    37441 ttgacgatgc tgaatattat ggctttaata agtttaaaaa tcgtatcaat agagacttag
    37501 atggttatca ctatcatgaa gatattaaag ggtacgctct aaaattagaa aaaaaattat
    37561 gtgattatgg ctacaaagat ttaagggagc ttattgataa agcttttgat aattaccaac
    37621 aagccatgtc ttccttaaac tggcaagata agagtgagtg ggattattat cagtcttgta
    37681 tggtgagact ttacttgtca ctcttaaaaa acgctgatat tttggacaca gtaaatgcct
    37741 atggccttaa gataagtcct atggataaaa cagagcgatc ctttctaaaa cactcctatt
    37801 tagcggccat tgaacaaaaa tatgctagct ttggacagcc aaacaatcag ttgaacacta
    37861 ttcggacaga aatcgctgag cgtgttaaag aaagaggtaa acgagattcc aaggggattt
    37921 atcgcttaga tttaccgaca ggagctggca agactaatct tagtatgcgt tatgcgtttc
    37981 accaattagt tcatcacgac aaatcaaggt ttttttacat aacgcccttt ctttcggttc
    38041 ttgaacaaaa tgcttccgaa attagaaaag ttacaggtga ccttggcgtc ctagaacacc
    38101 attccaatgt ggtgaaacag gctaatgaag atgatgatga caaggacagt ttattgtcag
    38161 cttatcttag tgatagctgg gacagtcaag tagtcttgac ttctatggtt caatttttcc
    38221 aaacactttt caaaacaaaa tcagctaatc tgagacgttt ttcaagtttg attaatagtg
    38281 ttgtgattct agatgaagtt caatccctgc ctattgaagt caccactttg tttaatttaa
    38341 cgatgaattt tttaaataaa gttatggata caaccatcgt tctttgcaca gcaacacaac
    38401 ctgcttatga ttcttcagag attgaccatc gtatctgtta tggagggaac ttgggagaat
    38461 tagctgaaat cgttgagtta acgattgaag aaaaacagat tttttcaagg acagagctta
    38521 gaaaatttga tgatagtgat cagaaagttc acttgactga tgttattaat cttattctag
    38581 gtgaggaaaa ctcagttctt gctattttta atacgaaaaa aacggttcat aactgctata
    38641 ctatgctaaa agacattact gatagaccgg tctatcagct ttcgacaaat atgtgtgcgc
    38701 agcatagact tgacttgatt gctaagatca aaacggagtt acaaaataat atccctatta
    38761 tttgtattag cacgcaatta attgaagcag gtgtagatgt tgattttcat cgcgtcattc
    38821 gttcctactc agggattgat tctattgttc aggctgctgg acggtgtaac cgagaaggca
    38881 aacgagataa agggcaagtc actcttgtca atctgaccaa tgaagaggaa aatatttcta
    38941 ggctgacaga aataaaagct aaaaaagaag ccacagaatc tattcttcat aagattgggt
    39001 ctccaattga tatctcaact ttaaaccgtg acttttttga gtattattat gccaataatc
    39061 agggactgat ggattatcct ttggaagaca acctatcaat ctacgactat ttaagcctta
    39121 atatttatca gacggcaaat aaaaagttca aaggtaagtt aaaacaagct tttaaaacag
    39181 caggagccaa aatgaacctc atcaataatg atatgatagg aattctcgta ccttatggcg
    39241 aagctgagaa aaaattggct tatttagaag aattgggtat gtctcacttt ttatcagcag
    39301 aagattatca aacgataaaa tcattactaa aagagttaca accttttacg gttaatgtcc
    39361 gcgagaacga tcctctcttt gagacaacaa aatcttatct aaatggtcag attctggttt
    39421 tgacgtcgga gtattatgac acggaaagag gagttaaata cgattcagct agcttttact
    39481 tctaactcaa aacgaaagca gattaacaaa aggttgttag aggaccttgt taacctgcca
    39541 atcatcatta ataattatta tcaatttaga ctatttaata aaattagatt acaaaaaaac
    39601 agaaggagga aagtagcttg tacagatcta gagacttcta cgtgagagta agtggtcagc
    39661 gagctctttt tacaaatcca gccacaaaag ggggatcgga acgctcatcc tattcggttc
    39721 cgactagaca ggcactgaat ggtatcgttg atgccatcta ttataagccg acctttacta
    39781 atatcgtcac agaggttaag gttattaacc agattcaaac cgaattacag ggtgtcaggg
    39841 ctctgttaca tgattatagt gcagatttaa gttatgtatc ctatttgagt gatgttgttt
    39901 atctgatcaa gtttcatttt gtttggaatg aagatagaaa agatttgaac tcagatagac
    39961 ttccagctaa acatgaagcc attatggagc gttctattcg taaaggggga cgtcgagatg
    40021 tgtttttggg tacaagagaa tgtttagggc ttttagatga tatcagccaa gaagagtatg
    40081 agactactgt gtcgtattat aatggtgtca atatcgactt gggaatcatg ttccattcct
    40141 ttgcctatcc gaaggacaaa aagacaccat taaaatcata ctttacaaag actgtgatga
    40201 aaaatggagt cattacgttt aaagcacagt ctgaatgcga tattgttaac acgctttcta
    40261 gttatgcttt taaagcacca gaggagataa aatcggttaa cgatgaatgc atggagtatg
    40321 atgccatgga gaaaggagaa aactgatgga tttttttact tctctcttga agacttatga
    40381 aaaagcagag ctagcagact tggttgatca ccaaaaaaga agtaatgagc cggttttact
    40441 gccgatttat catacgagtt taaagtcaaa tggcaaaaat atcatttcag tgaaacttga
    40501 caaagatggc cagtttcaca aggcagaatt tatggcagat aagcaaatga ttatttttcc
    40561 tgtaacggct gattctgttg ctaggtcagg tagtcatcct gcaccgcatc ccctagtcga
    40621 taaatttgct tattatagtg ctgaaatggg gcagtctcag tatgattctt ttcataagca
    40681 acttaataac tggattgatt attgtgagga gggtgacgtc aagaggtttt taaccattgt
    40741 tcagcaattt attttgaaac cagaatttct gacactgatt ctcgattctt taattggtcc
    40801 tgattatcaa aataatcaat taaaagtcac attttgtgat gccactggaa aagaaaaatt
    40861 aattgattta tcagcttgct ttttagaatt ttcaattgat cagttccagg gctttaaaaa
    40921 tgaatcggtt tcgacattta aaactttaca ccaatcctat atttcttttg ttgaagccaa
    40981 tcgtgaaaag cttggtattt gtaatattag tggacgagag gaacagctta ccgataagca
    41041 tagaggtttg atggggaatg ctaaaatcat ctctgttagt aataaaagag aagcttataa
    41101 aggacgtttt agagaacgtg aagatgtttt tagtgttggc tatgaaactt ccgaaaagat
    41161 tcatttaatg ctcaagtacc ttttagaaaa taaaaatacc agtacttggt tagggtcttc
    41221 tcaatattta atcaactggt ttagtgatga tttaacaaat gatagtcggt tggatatcgt
    41281 atcaccaatc tttgatgacg gacttgaaga agatgatgac gacgatacgc ctcctgttat
    41341 aacattagca actgaagaca ataaaagaat tggtaaatca ttcatcaagg gacaaaaatt
    41401 atttgctaat gatgccactt actacgttgc tattttgaat aaaaccagca atgggcggat
    41461 tgctttaaaa tattttcgtc agcttcaagc gtcccaatta ctcaccaatc ttaacaagtg
    41521 gcaggaaaca tacagttggg agtcgcgatc taagtttgga aaaagtcgct taagaacccc
    41581 tacttttcat gacatcctta atgtgtccta cggggttgat agggatcgct tccttgaatt
    41641 agataatgat aacttcaaaa gtgatcaaat tcaaaagtta gtggcaagtt tgattgatgg
    41701 taaaccgatg ccacagtcca ttgtcaaaaa gttaggtaac aatgttaaag aacgacatcg
    41761 ttaccgtaag cactggtatc aagttgagca ggtctgctta gcaattttac acaaacaaaa
    41821 tggggaggaa ttttcaccga tgctagatca taccaatcaa aatcgttcct atctttttgg
    41881 acgattatta gcaatttttg aattaatcga gaccttgcgt tatggcttgg atggaaacaa
    41941 taacgaccgt attaccaatg ctgaacgtta ttggacagcc tatactggac agccaacaaa
    42001 attgatgatg ttattggaaa ataaaattaa gccttacgaa gaaccattga aattaaatcg
    42061 tcgtggcagt tggatgaaat tagaaaaaga aaaagaagag attttagaac tgttaaatcc
    42121 tctgttagaa acagaaacaa tgggaaaacc cttagattac cgctttattt ttgggtatta
    42181 tgctgagaaa aactattact atacaaaaca aaacacggaa gtaacagaaa gtgaggagta
    42241 aaaagatgtt ggaacacaaa attgatttta tggtaactct tgaagtgaaa gaagcaaatg
    42301 caaatggtga tcccttaaat ggaaacatgc ctcgtacaga tgccaaagga tatggtgtga
    42361 tgagtgatgt ctccattaaa cgtaagattc gtaatcgttt gcaagatatg gggaagtcta
    42421 tttttgtgca agctaatgag cgtattgaag atgattttcg ttcactggaa aaacgctttt
    42481 cgcaacattt tacagctaag acacctgaca aagaaattga agaaaaagca aatgcattat
    42541 ggtttgatgt tcgtgctttt ggacaagttt ttacttatct gaaaaaatca attggggtgc
    42601 gtggaccagt ttccatcagt atggctaagt ccttggagcc aattgtcatt tccagccttc
    42661 aaattacgcg tagtaccaat ggtatggaag ctaagaataa tagtggccgc tcttctgata
    42721 cgatggggac aaaacatttt gtagattatg gtgtgtatgt acttaaaggt tctatcaatg
    42781 cttattttgc tgaaaagact gttttttctc aggaagatgc tgaggctatt aaagaagttt
    42841 tggttagctt gtttgaaaat gatgcgtcgt ctgcacgtcc ggaaggctct atgcgagttt
    42901 gtgaagtctt ttggtttacg cattcaagca aattgggaaa tgtttcaagt gcgcgtgtct
    42961 ttgacttgtt agagtataat caatcaatag aagaaaaaag cacttatgac gcttatcaga
    43021 ttcatctaaa tcaagaaaaa ttggctaaat atgaagcgaa agggttaacg cttgaaatcc
    43081 tagaaggact ctagtatggt ctatgccgaa gatgattatt taatgctatc aggtattcag
    43141 catttccaat tttgtaaacg tcaatgggcg ttgatccata ttgagcaaca atggcttgat
    43201 aatgaagcga cagcgcatgg acaggtttta catactaaag cagataaccc ttacattaaa
    43261 gaaaaacgaa aagagctttt ggtctcacgt gctatgccca tttcttctgc agaacttgga
    43321 ctttcaggaa ttatggatgt tgtggaattt tataaagatg atcaaggtgt gtctttgagg
    43381 ggaaaacgtg ggaaatggtt accaaaagtt gtggaataca agcgcggaaa acctaaaaaa
    43441 gataccagag atattgtcca gttggtggct cagaccatgt gtttagaaga aacgctagac
    43501 tgcgacatta acgaaggttg tctttattac catagtgtca atcaaagagt gattgttcct
    43561 atgacatcag ctttgcgtca agaagtgaag gaattagccg cagagatgca tgaggtttat
    43621 cagagtcaaa tgctacctaa agcagcttat tttaaaaact gtcagctttg ttctttagtc
    43681 gatatttgta agcccaggtt gagtaaaaaa acaaggagtg tgtcgcgtta catcaatgag
    43741 gctatgacca gtgaggagat ggacctatga agaagttgct aaataccttg tatttgacgc
    43801 aagaagattt ttatgtcact aaagagggcg ataacattgt tatcaagcaa gaaggtaagg
    43861 ttctcaaacg gtttccgttt cggattattg acggtattgt ctgtttttct tatttgggtg
    43921 tgtcgcctgc tttggtgaag ttatgtacgg agaatcagat taatttatcg tttcatacac
    43981 cacaagggcg tttttgtggt cgctatattg gttcaaccaa tgggaatgtg ttgttgcgta
    44041 gagaacatta tcgtttatct gatcgtgagg aatctttgga atacgcaaag cggtttattt
    44101 tggctaaaat ttccaattca aggaaatact tgctacgctt taaacgagat catcgtcaac
    44161 agattgatac caagcttttt gaggctgtta atgacgaatt gatatgggct ttagagatgg
    44221 ttcaggcagc agataataaa gactctttaa gagggattga aggccaagct gctaatcagt
    44281 attttcgcat atttaatgac ctggtgttga cggacaaaaa aacgttttac ttccaaggtc
    44341 ggagtaaacg accaccctta gattgtgtta atgccctctt gtcttttggt tacagtttac
    44401 tgacctttga atgtcaatct gccttggaag ctgtcggatt agacagttac gttggtttct
    44461 ttcacacgga tcgtcctggg cgtgctagtt tagcgcttga tttagttgaa gagttccgct
    44521 catatattgt agatcgtttt gtcttttcat taattaataa aggacaactt cagaaaaaac
    44581 actttgaggt taaagaaaat ggtagtattt tattgacgga aaatggcaga gctattttta
    44641 ttgatttgtg gcagaagcgt aagcatactg aggtagaaca tccttttaca aaagagaaag
    44701 taaaacttat gttattaccc tatgtacaag cgcagctttt agctaaggcc atacgaggag
    44761 atttagaaag ctatccacct tttatggttt aggagatgtt atatgatggt tttagtcact
    44821 tatgatgtaa atacggaaac acctgctggt agaaaaagat tgcgtcatgt tgccaaactc
    44881 tgtgtggact atgggcaacg tgttcaaaat tctgtttttg aatgttctgt gacacccgca
    44941 gaatttgtgg atataaagca ccgcttaaca caaatcattg atgagaaaac tgatagtatt
    45001 cgcttttatt tattggggaa aaattggcag aggcgtgtgg aaacacttgg tcgctcagac
    45061 agctatgacc cagataaagg tgtcttatta ttgtaaaaat ctcttgtgcg aagctagctt
    45121 tcacagaaaa accttgcttg ctcgcgcaaa aataacttaa aaaagaagcg aaatggagat
    45181 aaaaaggctt aaaacacctc tatgtgtgcc atccgtttct ctataaactg tgtcatttgg
    45241 cgcagtctca cccttcatgg gtgagtggat tgaaatatcg attttgcaga taaaaggaaa
    45301 catagagttc gtctcaccct tcatgggtga gtggattgaa atatgaacta ggacatattg
    45361 aacatgattc tggccaatgt ctcacccttc atgggtgagt ggattgaaat agattcggct
    45421 agatattcta aaaaatcgat aaagcgtctc acccttcatg ggtgagtgga ttgaaattcc
    45481 aacttttgta aaagtagaat ttgctacgtt tggtctcacc cttcatgggt gagtggattg
    45541 aaatattatt ttattaaagt tatcacgtaa attttgcaag tctcaccctt catgggtgag
    45601 tggattgaaa tcattatatg aacaatgcct ttgcggaatt agttgtctca cccttcatgg
    45661 gtgagtggat tgaaagatga acccgacctc attaaaagag aggtcgggtt tttacatgcc
    45721 tttagtcaac catttatctg atagcgtatc aaattcaagt ttttgcatgt tctagtctat
    45781 ggtttgcgcc actagctttc ggtaaactaa gggtaactta agagaggagt tatttatgat
    45841 actatcactt gtattaatgg tatcggtttt tggggcaggc ttgttatcat ttttctctcc
    45901 gtgtatcttt ccggtccttc ctgtctattt aggcatttta ctggatgcag atgattcaaa
    45961 gacgattact atatttggta aaaaactcta ttggtatggc attgtcaaaa ctttagcctt
    46021 tatttttggt ctatctacta tttttgtgat tttaggttac ggggctggtt ttttaggaaa
    46081 tatcctttat gcggtatggt ttcggtactt actgggagcc ttggtcatta tcttggggat
    46141 tcatcagatg ggcctcatta ccattaagag cttacaattt caaaaatcac tgactttcca
    46201 taataacaag aatcgcaacg gtttgttcaa tgcatttatc cttggtttaa cctttagctt
    46261 tggttggacg ccttgtgtgg gacctgtttt gagttctgtc ctagcattgg tggcttcagg
    46321 gggaaatggt gcctggcaag gtggcgtttt gatgattatt tatactcttg gattgggcat
    46381 tcctttccta ctcatctctt ttgcgtcagg cattgttttg aaacagttta acaagctcaa
    46441 accccacata cttttactga aaaaagtagg aggcgttctg attatagtca tgggaatctt
    46501 gcttatgaca ggaaccttaa ataacttagc acaacttttt ggataaagga gaaacacaat
    46561 gaaaaaagga ctattagtaa caactggttt ggcttgtctc gggctactaa ctgcttgctc
    46621 aacccaagac aatatggcta aaaaggaaat aactcaggac aagatgagca tggcagctaa
    46681 aaagaaagat aagatgtcaa catcaaagga caagtccatg atggcagata aatcatctga
    46741 taagaaaatg accaatgatg gtcctatggc gcctgatttc gaactcaaag gcatcgatgg
    46801 taagacctat cgcttatcag agttcaaagg taaaaaagtt tatttgaaat tttgggcctc
    46861 ttggtgttca atctgtctat caaccttggc agataccgaa gacctggcta aaatgtcaga
    46921 taaagactat gtggtcctaa cagttgtctc accaggtcat caaggggaaa aatcagaagc
    46981 agactttaaa aaatggttcc aaggaacaga ctataaggac ttaccagtct tgttagatcc
    47041 ggatggcaag ctattggaag cttacggcgt cagatcttac ccaacagaag ttttcattgg
    47101 aagtgatggt gttcttgcta aaaaacacat tggttatgcc aaaaaatcag acatcaaaaa
    47161 gacccttaaa ggtatacatt aggaaggacc agctgatagg cattagaaaa aaggagttga
    47221 gtttatggaa cacaaatgga aattatggct atttatcgtt ggagtggtct tgttaatagg
    47281 cggagcttct gttctcattc agaaaggtca agccaaggct tttagtcaag gcaagcctca
    47341 actaccagct aaaaaagtca aatccactaa agtagatccc aatgcccctg ttgatcaaaa
    47401 aatgatttac ctagctggtg gctgtttctg gggcgttgaa gaatattttt cacaagtgga
    47461 tggcgtctta gatgcggtgt caggatatgc caatggtaga ggcgatacca ctaattacca
    47521 gttaattcat cagactggtc atgcagaaac cgttgaagtg gcctatgatg cgaaccgtat
    47581 tagcttgaaa gaattattac tgcatttttt ccgaattatt gacccaacca gtcttaataa
    47641 gcaaggaaat gatcgcggta gtcaataccg aactgggact tactatactg acaaagcaga
    47701 tttagctatt attgatgagg tcttcaaaga aaaagctaag gattacaaga aaaaaatagt
    47761 ggttgaaaaa gcaccattga aacactttat taaggcagaa gactaccacc aagattacct
    47821 caagaaaaat ccaaatggct actgccatat tgatattaac caagcgactt atcctgtgat
    47881 tgatgaaagc aagtacccaa aaccaagtgc cactgagatc aaagcaaaac tatctgcaga
    47941 cgaataccga gtgacgcaaa aaaacgaaac tgaaaaagcc ttttcaaacc gctactggga
    48001 ttcttttgat gcaggaattt acgtagacgt tgtgacagga gaaccgcttt tctcttcaaa
    48061 agacaaattt gaatcaggtt gtggttggcc aagttttagc cgccccatca gcccagatgt
    48121 tattcgttac aaggaagata agagtttcaa tatgacgaga acagaggtgc gcagccgttc
    48181 aggggattct catctggggc atgtctttac tgatggacct aaagaccaag gtggccttcg
    48241 ttactgcatc aatagcttgt ccattacctt tattccaaaa gctgatatgg aagctaaggg
    48301 ctatggttat ttattatcat ctgtagaata gggttaggcc taaaaatctg atataataga
    48361 agaaagacta atatgagagg gccatgcaag gccctttata aagataagga gacaccgtgt
    48421 gtactcattg ttaattgtag aagacgaata ccttgtgcgc caaggtattc gttctttggt
    48481 tgattttagc cagttcaaga ttgatcgggt caacgaagca gaaaatggcc agttggcttg
    48541 ggacttgttt cagaaagagc cttatgatat tgttttgacg gatatcaata tgcccaaatt
    48601 aaatgggatt caactagcag aactcattaa acaggaatcc ccccaatctc atctggtatt
    48661 tttgacgggc tacgatgatt ttaactatgc cttatctgct ttgaaattag gggcagatga
    48721 ttacttgctc aaaccctttt ccaaggcaga tgtagaagac atgttaggaa agctccggaa
    48781 aaaattagaa ctttccaaga aaacagaaac cattcaggaa ttggttgagc agcctcaaaa
    48841 agaagtatca gcaatagcaa tggctattca tgagcggttg gcagattctg atttgaccct
    48901 aaaaagcttg gctcagcagc ttggttttag ccctaattac cttagcgtct tgattaaaaa
    48961 agatttaggg atgccctttc aagattatct ggtacaagaa cggttgaaaa aagccaagct
    49021 tctcttgtta accagtaatc ttaaaatcta tgaaattgca gagcaggtcg gctttgagga
    49081 catgaattat ttttctcagc gctttaagca actggtaggt gttaccccaa gtcagtataa
    49141 aaaaggaggt caggcatgaa gcgttatccc ctactggtcc agttgatttc gtatgtcttt
    49201 gtgatcgtaa ttgcccttat taccacactg ggcttactct attaccagac cagttctcgt
    49261 aatatcaggc agttaattga acgtgatact cggcagagca ttcggcaaag ttcccaattt
    49321 attgacgctt acatcaagcc tcttaaagaa acaacttcgg tgctggcgaa aaatacggaa
    49381 attcaagcct ttgctagtca aattcatcaa gaaaatgaca agcaggtcct tcagctcatg
    49441 aagatggttc ttgcgaccaa ttccgattta caagcagctg ttctggtgac taaggatggt
    49501 cgaacggtgc ctaccaattc tcagttgacc atgaaaacct ccagtgacat gatggcagaa
    49561 ccctggtata aagcagccat agaccgtcag gccatgccag tcttgacccc agctcggcaa
    49621 ttatcccttt cttctaaaaa agaatgggta gtttctgtga cccaagaggt agtggatgct
    49681 gctggtcata atttaggcgt gctaagactt gatattgcat acccgaccat taaagcgtct
    49741 ttagatcagc ttcagctagg ccgccaaggc tttgccttta ttgtgaatga taagcatgaa
    49801 tttgtttacc atcccaaaaa gagtgtttac agttcttcta aggagatggc tgcgatgaag
    49861 ccttatttag cgattcagaa tggttacact aaggacaaga catcttttgt ttaccaaaaa
    49921 ctcattccta acagtcaatg gactttagtg ggagtggcgt cactggatca gttgcaccgg
    49981 gtgcagcgcc aaattttttg gtcctttctt ggaacagggc ttctagcctg tctgatttgt
    50041 ggctttgcaa ctgtcttagc cttacgcaga tggattcgtc ccattcaaca attgcagcaa
    50101 gttattcttg ctattcaaaa aggagatcgt cagttacgtg cccaagaaac gggttctcca
    50161 gaattgacag accttgccca acagtttaat gcgctcttag atcaaattga tagcttgatg
    50221 gttgccgttg cggataagga aaaggcgatt gggcagtata ggttacaagc cttggctagt
    50281 cagattaacc cgcattttct ctataacacc ttggacacta ttatttggat ggcagaattt
    50341 aatgacagca agcgcgtggt agaagtgacc aagtctctag ctaagtattt tcgtttggcc
    50401 cttaatcagg ggaacgaata cattcgtttg gcagatgaac tggatcacgt tagccaatac
    50461 ctctttattc aaaaacagcg ctatggagac aagctaagtt atgaagtgca aggcttagat
    50521 gtctacgcag actttgttat tcctaagctt atcttacagc ccttagtaga aaatgctatc
    50581 taccatggca tcaaagaagt cgatcgcaaa ggcatgatca aggttacggt atctgataca
    50641 gctcagcatc tggtgttgac tgtttgggat aatggtaaag gcattgaaga ctcttcactg
    50701 accaatagtc agagcttgtt ggctagggga ggtgtgggcc ttaaaaatgt tgaccagcgg
    50761 ttaaaacttc actatggtga aggctaccac atgaccattc atagccagtc agaccagttc
    50821 actgaaatac aattaaccct tcctaaaatg catgaattaa tggcagacga cacacaggaa
    50881 aatgagtaag gttacaggaa gtgcatgtca gccatttccc taagttaggg tattggagat
    50941 aagaacctta gaaaggatat catgagttta gcatctgact attttagccg acagaccccc
    51001 atagttgaaa agctaatggc ttacggtttt gaaaaacgaa ataatggtta cttctataac
    51061 gaacggttta tggaagaaga atttgaggcg cagcttagga ttgatgaggc tggcaatatc
    51121 tgggatcggg ttattgattg tgacttggag gaggattatt tgcctttaca acaagcagct
    51181 tggcaaggaa cctatactgg gcaggttaga gcggcctatt tggaactttt ggagcgctta
    51241 tcagtagcct gttttgaagt cactcctttt cagtcaatgc aagctaatag acttgctaag
    51301 catatcacca aagaatggtc tgacccaatg gactatcctt ttgaaaagca cccagacctt
    51361 gcaacctatc gggtaggggg caaatggtat gctatgattt tttctctctt ggctgataaa
    51421 ttagaccaga taccagagag attagtagga cagacatgtg aagtgatgac tgtcaaagtt
    51481 aatcccaagg atttacctca gttactgcag caagaaggca tttacccagc gtatcacatg
    51541 tcaaagaaaa actggattag tattattttg gatgataagg taacagatga taagctttgg
    51601 acgttagtga ctcaaagtcg tcaactagtc aacccaaacg gtctttctaa tcctaatggt
    51661 cctgattatt gggtcattcc agctaatttg aaatactatg atattgatgc agaatttgca
    51721 gccaatgatg tgattttatg gacccaaaaa gctggtattg ccgtgggaga ctacgtgctg
    51781 atttatatga cagctccagt caaatccatt cgctatgcct gccaagttct agaaactgat
    51841 atacctaacg agggttatcg taaaaatcct aacattgaca aactcatgcg tctccgaaaa
    51901 tgccaacagt acaaggatgg tctcttgtct tttgacctta tgaaaaaaca tggcgtagct
    51961 gcagtgagag ggccaagacg attaagccct caattaattg catttttaaa ggaaaaagag
    52021 tatcttaaag aaaacaacta aggggactaa aggagaataa gagatggttg aatttgtagc
    52081 agatcaaagt ttttgggaac tttttccaga tgccaaacta ggtgtcgtct tattaaagga
    52141 tgttcagaat caagcagagt caccagaaga tgtcaaacag ctcttagcag atagccatga
    52201 gttggtaaaa gcttatttaa cagcagacaa ttttagtgat aatcaggtgg ttcaagtcta
    52261 ccgcaaggcc tatcaacact ttaaaaccaa aaaaggagct cgctctagca ttgaagccct
    52321 tctcaagcgg gtgtcaaatg gtcaaagcat tccgtctatt aacccactag tggatattta
    52381 taatgcggct agtctacgtt ttggtttacc tgttggagcc gaagatagtg acagttttat
    52441 cggagatttg cgtctgacga caacagatgg tggtgacgac ttttacttga ttggggatgc
    52501 tgacaacaac ccaaccttgc caaatgagct gtgttataaa gatgatattg gagcggtttg
    52561 tcgttgcctt aactggcgag atggcgaacg caccatggtg acagaacaca ccaaaaatgc
    52621 atttctgatt atcgaagctc ttgatcaaga aggtcaaaat agattgcaag aagctcttga
    52681 cttcattgaa ggcagcgcta aaatgtacct tcatgcaatc acttctgtgc atgtgttgga
    52741 taaagacaat ccacacgtgc cactttttac agaaaactag attagtagga tgagctgtgt
    52801 aaaatagaag gttaacaaaa aagcgagtaa acgaatgtcc tgtcatttag gttttcgttt
    52861 actcgctttt tgatgagatt ttactgctgt cctagcaaaa ggtgaggatg aggtcgtata
    52921 tcacatagag gttttctgtt aagccttatt tgttactaaa gaagaaaggt ggcgtgtaat
    52981 gactaagggt ttcgtaacaa gccttggctt gctcattgtc ttcacagaca atcaagcaag
    53041 tatcatcacc acagaccgtt gctacaattt ctggaatttg catggcatct aaaatggagc
    53101 caaaggattg ggctagtcca ggtaacgttt ttaaaataat ttgatgttga actatcttta
    53161 acatgaccaa agcgtcttcc atgtaaaaac gaagacgatg ttcccagcgg gtttgtgaaa
    53221 tggctaacgc ttcatagtgt gtgtcgtttc cagaagttac tttgaccagg ttcaattcct
    53281 tcatgtcacg tgatagggta gcctgagtga tcgtgatgcc atttttttgc aaccgttctt
    53341 gtaattcttg ctgtgtatgt atagttgtct cagagatgag ggaacgtatg agttggtgac
    53401 gcgtctcttt cttattcatt gttataatct tcctttaacg taattgataa caatccgagt
    53461 atagcaaaaa gaggagaagg tgtaaagttt ttgatgaacc gcttacaaaa tggctttttt
    53521 atggtaaaat aaagatgatg tttagaaaaa ggagatttgt gtgattcgaa gagaagatta
    53581 tcaatacctt agaaaactaa acgattttcg ctacttttct attgaacaat ttgacaaaat
    53641 tgtagggcag atggaattcc gaaaagctaa aaaggaccat atcctttttt ttgagggaga
    53701 taaaagagat aagctttttc tagtgacctc tggttatttc aaggtggagc agtccgatca
    53761 atcaggaacc ttcatgtata cggatttcat cagacacggc accatttttc cttacggtgg
    53821 cctctttaca gatgattatt accatttttc agtggtagcc atgacagacg tgacttattt
    53881 ttactttcca gtcgatttat ttgaagagta ttcgcttgaa aatcgtctac aaatgaaaca
    53941 cttatatagt aagatgtcta agctgctcga gttacatgag ttgagggtcc gaaacttgat
    54001 tacatcaagt gctagttctc gtgtgattca atctctggcg attttgctgg ttgaaatggg
    54061 taaagacagt gataccttac cttttcaatt aacaacaaca gatattgctc aaataagtgg
    54121 gacgacaaga gaaacagtta gccatgtgct tagggatttg aagaagcaag aattgattac
    54181 cataaaaggt aagtatttga cttatctaga taaagactat tttttacaat acacaaagtg
    54241 aattaaaggt cagaacactt tattttaaaa gtttttctga cttattttaa tttataagta
    54301 taaattt
//
LOCUS       DAUGUF010000009        52310 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUGUF010000009 DAUGUF010000000
VERSION     DAUGUF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52310
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.009"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            175..1410
                     /gene="arcA"
                     /locus_tag="VIB71_000524"
     CDS             175..1410
                     /gene="arcA"
                     /locus_tag="VIB71_000524"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEQ8822279.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1449..1802
                     /locus_tag="VIB71_000525"
                     /pseudo
     CDS             1449..1802
                     /locus_tag="VIB71_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            1842..2855
                     /gene="argF"
                     /locus_tag="VIB71_000526"
     CDS             1842..2855
                     /gene="argF"
                     /locus_tag="VIB71_000526"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEQ8822280.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3025..4518
                     /locus_tag="VIB71_000527"
     CDS             3025..4518
                     /locus_tag="VIB71_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEQ8822281.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4535..5866
                     /locus_tag="VIB71_000528"
     CDS             4535..5866
                     /locus_tag="VIB71_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEQ8822282.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFYTYIDPKGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTEPFDC
                     VEAGGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLETLQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTQ"
     gene            5886..6836
                     /gene="arcC"
                     /locus_tag="VIB71_000529"
     CDS             5886..6836
                     /gene="arcC"
                     /locus_tag="VIB71_000529"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEQ8822283.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALMSTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7150..8142
                     /locus_tag="VIB71_000530"
     CDS             7150..8142
                     /locus_tag="VIB71_000530"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEQ8822284.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            8265..8804
                     /gene="rsmD"
                     /locus_tag="VIB71_000531"
     CDS             8265..8804
                     /gene="rsmD"
                     /locus_tag="VIB71_000531"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEQ8822285.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8794..9285
                     /gene="coaD"
                     /locus_tag="VIB71_000532"
     CDS             8794..9285
                     /gene="coaD"
                     /locus_tag="VIB71_000532"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEQ8822286.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9272..10309
                     /locus_tag="VIB71_000533"
     CDS             9272..10309
                     /locus_tag="VIB71_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEQ8822287.1"
                     /translation="MKRLNKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10714..11691
                     /locus_tag="VIB71_000534"
     CDS             10714..11691
                     /locus_tag="VIB71_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8822288.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFENIQ
                     LEASSNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERKTIRKR"
     gene            12115..12759
                     /locus_tag="VIB71_000535"
     CDS             12115..12759
                     /locus_tag="VIB71_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEQ8822289.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRGSKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12763..13842
                     /gene="rlmN"
                     /locus_tag="VIB71_000536"
     CDS             12763..13842
                     /gene="rlmN"
                     /locus_tag="VIB71_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEQ8822290.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSRIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSLKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(13924..14550)
                     /locus_tag="VIB71_000537"
     CDS             complement(13924..14550)
                     /locus_tag="VIB71_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEQ8822291.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            14778..15305
                     /locus_tag="VIB71_000538"
     CDS             14778..15305
                     /locus_tag="VIB71_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEQ8822292.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            15447..15650
                     /locus_tag="VIB71_000539"
     CDS             15447..15650
                     /locus_tag="VIB71_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEQ8822293.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            15655..16626
                     /locus_tag="VIB71_000540"
     CDS             15655..16626
                     /locus_tag="VIB71_000540"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEQ8822294.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIVASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            16636..17025
                     /locus_tag="VIB71_000541"
     CDS             16636..17025
                     /locus_tag="VIB71_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEQ8822295.1"
                     /translation="MSPITLILWLLLVGIAGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            17207..19048
                     /gene="typA"
                     /locus_tag="VIB71_000542"
     CDS             17207..19048
                     /gene="typA"
                     /locus_tag="VIB71_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEQ8822296.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            19170..19421
                     /locus_tag="VIB71_000543"
     CDS             19170..19421
                     /locus_tag="VIB71_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEQ8822297.1"
                     /translation="MFYLIMAVLIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQIPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            19777..21135
                     /locus_tag="VIB71_000544"
     CDS             19777..21135
                     /locus_tag="VIB71_000544"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEQ8822298.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLNDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATKKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            21135..22217
                     /locus_tag="VIB71_000545"
     CDS             21135..22217
                     /locus_tag="VIB71_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEQ8822299.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIIAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            22218..23366
                     /locus_tag="VIB71_000546"
     CDS             22218..23366
                     /locus_tag="VIB71_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEQ8822300.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKPKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMYDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQAPPSPETVLEQAHG"
     gene            23578..24942
                     /gene="ftsA"
                     /locus_tag="VIB71_000547"
     CDS             23578..24942
                     /gene="ftsA"
                     /locus_tag="VIB71_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEQ8822301.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            24966..26285
                     /gene="ftsZ"
                     /locus_tag="VIB71_000548"
     CDS             24966..26285
                     /gene="ftsZ"
                     /locus_tag="VIB71_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEQ8822302.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            26288..26959
                     /locus_tag="VIB71_000549"
     CDS             26288..26959
                     /locus_tag="VIB71_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEQ8822303.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKCMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            26971..27627
                     /locus_tag="VIB71_000550"
     CDS             26971..27627
                     /locus_tag="VIB71_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEQ8822304.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            27632..27886
                     /locus_tag="VIB71_000551"
     CDS             27632..27886
                     /locus_tag="VIB71_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEQ8822305.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            27886..28677
                     /locus_tag="VIB71_000552"
     CDS             27886..28677
                     /locus_tag="VIB71_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEQ8822306.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            28687..29445
                     /locus_tag="VIB71_000553"
     CDS             28687..29445
                     /locus_tag="VIB71_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEQ8822307.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            29718..32519
                     /locus_tag="VIB71_000554"
     CDS             29718..32519
                     /locus_tag="VIB71_000554"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEQ8822308.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDIRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEYESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGVAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(32783..33085)
                     /locus_tag="VIB71_000555"
     CDS             complement(32783..33085)
                     /locus_tag="VIB71_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEQ8822309.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(33136..33591)
                     /locus_tag="VIB71_000556"
     CDS             complement(33136..33591)
                     /locus_tag="VIB71_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ8822310.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(33719..36001)
                     /locus_tag="VIB71_000557"
     CDS             complement(33719..36001)
                     /locus_tag="VIB71_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8822311.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQIAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            36299..36529
                     /locus_tag="VIB71_000558"
     CDS             36299..36529
                     /locus_tag="VIB71_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEQ8822312.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            36656..37342
                     /locus_tag="VIB71_000559"
     CDS             36656..37342
                     /locus_tag="VIB71_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8822313.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            37342..38076
                     /locus_tag="VIB71_000560"
     CDS             37342..38076
                     /locus_tag="VIB71_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822314.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            38225..39634
                     /locus_tag="VIB71_000561"
     CDS             38225..39634
                     /locus_tag="VIB71_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEQ8822315.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQHFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRVFNPVT
                     QSKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            39812..41506
                     /locus_tag="VIB71_000562"
     CDS             39812..41506
                     /locus_tag="VIB71_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8822316.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            41714..42568
                     /locus_tag="VIB71_000563"
     CDS             41714..42568
                     /locus_tag="VIB71_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEQ8822317.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKEGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            42721..44061
                     /locus_tag="VIB71_000564"
     CDS             42721..44061
                     /locus_tag="VIB71_000564"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEQ8822318.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDTSRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            44039..44254
                     /locus_tag="VIB71_000565"
     CDS             44039..44254
                     /locus_tag="VIB71_000565"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEQ8822319.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            44254..45126
                     /locus_tag="VIB71_000566"
     CDS             44254..45126
                     /locus_tag="VIB71_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEQ8822320.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASCQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            45119..45946
                     /locus_tag="VIB71_000567"
     CDS             45119..45946
                     /locus_tag="VIB71_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEQ8822321.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKELDFSPIQGGHGNIEFLAHLVKSQTPETLAPHLIQEVVAKAHKEFEKHEKK"
     gene            45933..46403
                     /locus_tag="VIB71_000568"
     CDS             45933..46403
                     /locus_tag="VIB71_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8822322.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            46424..48085
                     /gene="recN"
                     /locus_tag="VIB71_000569"
     CDS             46424..48085
                     /gene="recN"
                     /locus_tag="VIB71_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEQ8822323.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLEAELKSLEKQLVAAASELSVSRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            48257..49186
                     /locus_tag="VIB71_000570"
     CDS             48257..49186
                     /locus_tag="VIB71_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8822324.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFNDDSFISQNETDKMFENLTDDR
                     LLDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLRSLSD
                     TALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAHYEDR
                     KAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVAKRKIA
                     LPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            49402..50253
                     /locus_tag="VIB71_000571"
     CDS             49402..50253
                     /locus_tag="VIB71_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8822325.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            50246..51088
                     /locus_tag="VIB71_000572"
     CDS             50246..51088
                     /locus_tag="VIB71_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEQ8822326.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLTKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNIKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            51066..51653
                     /locus_tag="VIB71_000573"
     CDS             51066..51653
                     /locus_tag="VIB71_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEQ8822327.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            51752..52027
                     /locus_tag="VIB71_000574"
     CDS             51752..52027
                     /locus_tag="VIB71_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEQ8822328.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
BASE COUNT        16575 a         8995 c        11041 g        15699 t
ORIGIN      
        1 gaatacaaat ctataaaaat aaaaacaacg ctcaaaaaat gtaagcgatt actcaaaata
       61 actgtgagaa ataccctatt tttatctttt ttaaggagta cactaggaat ataagcaaga
      121 gttaagaatc ttgacggtga attcacaaaa accaattaga aagaggtaat tcttatgact
      181 gctcaaacac caattcatgt ttattctgaa attggaaaat taaaaaaagt gttgctccac
      241 agaccaggta aagaaattga aaatcttatg ccagactact tggaacgctt gttgtttgat
      301 gacattccat tcttagagga tgcccaaaaa gaacatgatg cttttgccca agctttgcgt
      361 gacgaaggta ttgaagtctt gtaccttgag accttagctg cagaatctct tgtcactcca
      421 gaaattcgcg aagctttcat tgatgaatac ctaagtgaag ctaatatccg tggaagagct
      481 actaaaaaag ccattcgtga gttgttgatg gctatcgaag acaatcaaga attgattgaa
      541 aaaaccatgg caggggttca aaaatctgaa cttccagaga tcccagcatc tgaaaaaggc
      601 ttgactgact tggttgaatc caattaccca tttgccatcg acccaatgcc aaacctttat
      661 ttcacacggg acccattcgc aactattggt acaggtgttt ctctcaacca catgttctca
      721 gaaacccgta accgtgaaac cctttatggt aaatacattt tcactcatca cccaatttat
      781 ggtggtggca aagtgcctat ggtttatgac cgtaatgaaa ccactcgcat tgaaggtggg
      841 gacgaacttg ttctttcaaa agatgtgctt gcggttggta tttctcaacg tacagatgct
      901 gcttctattg aaaaattgtt ggttaacatc tttaaacaaa accttggctt caagaaagta
      961 ttggcctttg aatttgcaaa taaccgtaaa ttcatgcact tagacactgt ctttaccatg
     1021 gttgactatg acaaattcac cattcaccca gaaattgaag gcgatcttcg cgtttactct
     1081 gtgacttatg acaacgaaga acttcatatt gttgaagaaa aaggtgattt agcagaactt
     1141 cttgctgcta accttggtgt tgaaaaagtt gaccttatcc gttgtggtgg tgacaactta
     1201 gtagcagcag gtcgtgaaca atggaacgat ggttctaaca cccttactat cgcaccaggt
     1261 gtggttgtgg tttataaccg taacaccatt accaatgcca ttcttgaatc taaaggcttg
     1321 aaattgatca agattcacgg aagtgaattg gttcgcggtc gtggtggacc tcgttgtatg
     1381 tcaatgccat ttgaacgtga agatatttaa taagctatgg taaaggtggt tataggtcag
     1441 aagccttttc aacaggacaa tttttagctg aaacgaaaat agaagcacga ttgacacgca
     1501 ttgtaacctt agcagattat tgtggttgcg gttatggtgc caaagtcact gaagcgctag
     1561 aaacttatac cagacgagaa ggcttttacc aactaaccat tcacagtgaa ctgacagcac
     1621 aaacctttta tgaaaactta ggttatcaga cctatggtcc caagtgttta gaagatggtg
     1681 agtattgtca gtcccttgca aaaaccattc ttaaatggga gaagaatatg gacatagcaa
     1741 tgctaattgc gattgttggt ggtctattag gctgctatct ctatctcaca aaaaataatt
     1801 aatcaaaaca gattacagtt aacactcgaa ggagacaata gatgacacaa gtatttcaag
     1861 gacgtagctt cttagcagaa aaagatttta cacgcgctga attagaatac cttattgatt
     1921 tttcagcaca tttgaaagat ttgaaaaaac gtggtgtgcc tcatcactac ttagaaggta
     1981 aaaacattgc cctcttgttt gaaaaaacat caactcgtac gcgtgcagct tttacaacag
     2041 cagccattga cctaggtgct cacccagaat acctcggtgc caatgacatc caacttggta
     2101 aaaaagaatc aacagaagac actgctaaag tattgggtcg tatgtttgat gggattgaat
     2161 tccgtggttt cagccaacgc atggttgaag aattggcaga attctcaggt gtgccagttt
     2221 ggaatggttt gactgatgaa tggcacccaa cccaaatgct tgctgactat ttaacagtga
     2281 aagaaaactt tggcaaactt gaaggcctta cccttgttta ctgtggtgat gggcgtaata
     2341 acgttgccaa ttcccttctt gtgactggtg ctatccttgg tgttaatgtt catatcttct
     2401 caccaaaaga actcttccca gaagaagaga ttgtgacatt ggctgaaggc tatgctaaag
     2461 aaagtggcgc tcgtatcctt atcacagaag atgctgacga agctgttaag ggcgcagacg
     2521 tcctttacac agacgtttgg gtatcaatgg gtgaagaaga caaattcaaa gaacgtgttg
     2581 aattgcttca accatatcaa gtcaacatgg accttgttca aaaagcagga aatgacaagc
     2641 ttatcttctt gcactgcttg ccagctttcc atgacacaaa taccgtttat ggtaaagacg
     2701 ttgctgaaaa attcggcgtg aaagaaatgg aagtcactga tgaagtcttc cgcagcaaat
     2761 acgctcgtca ttttgaccaa gctgaaaacc gtatgcacac tatcaaagcg gttatggcag
     2821 caacccttgg taacctcttt attccaaaag tgtaataagg actggtactc cttaactcat
     2881 ttcacatatc aatgtgaccc ctttaattta acaatttaac tacttaaaaa cgtactttaa
     2941 ctacatgaca agtcgttctg gttttcgcgt ccttgaccgg aactagaacg gcttattttt
     3001 atgaaaaggt aagaggtaat cattatgaca gaagaaaaaa aacggggttt tagaattcct
     3061 tcttcttaca ccgttctttt tatcattata gccatcatgg cagtgttaac ttggtttatt
     3121 ccagctggcg cctacgaaac cgctaagggc ggtggtgtta tttcaggaac ctacaaaaca
     3181 gtagcatcca atcctcaagg attttttgac atcttgatgg ctcccgttcg aggcatgtta
     3241 ggtgttgaag gcactgatgg tgctattcaa gtgtctttct ttatcttaat ggttgggggc
     3301 tttttaggag ttgtcaacaa aacaggtgct cttgacacag ggattgcgtc agtggttcgt
     3361 aaaaacaaag gtagagaaaa aatgttgatt gctattttaa tccctttgtt tgctctaggt
     3421 ggaacgacct atggtatggg ggaagaaacc atggcctttt acccactttt aattcctgtt
     3481 atgattgcgg ttggttttga cagtattgtt gctgtagcca ttattttgat tggttctcaa
     3541 attgggtgtc tagcctccac tattaaccca tttgcaactg gtgtagcagc tgatgctgct
     3601 ggtgtcagca ttgcagatgg aatgatttgg cgtgttatcc aatgggttat tcttgtcggc
     3661 atgtctattt ggtttgttta caattacgct agtaagattg aagaagaccc aagtaaatca
     3721 ttggttgcag acaaggaaga agagcataag gaactcttcc agttgcaaaa ttctggagaa
     3781 gacttaaaca agcgccaacg aaacgttttg accattttta ctttgacctt tgtcattatg
     3841 attcttagtt tgattccgtg ggaagatttt ggcatcaaat tctttactaa tatcaatact
     3901 tggttaacca caatgcctat cttaggggga gttattggga aaaccatggg agcatttggt
     3961 acttggtatt tcccagaaat caccatgctc tttatcatga tgggtgtctt agttgctatt
     4021 gtttatcgta tgagtgaaga agactttttt agctcttttt tgactggtgc aggtgaattt
     4081 ttaggtgttg ccatgatctg tgctattgca cgcggtattc aagttatcat gaatggtggt
     4141 atgattacag ccactatctt acacttaggt gaaacaagtc tttctggttt atcttctcaa
     4201 gtttttgtga tattagctta tattttctac ctcccaatgt ccttcttgat tccatcaaca
     4261 tcaggacttg ctggggctac aatggggatt atggcaccgc ttggacaatt ctcaaatgtc
     4321 cctgctcacc ttgttattac agccttccag tcagcttctg gaatcttaaa catgatttct
     4381 ccaacttcag caatcgttat gggagcactt gcgcttggtc gcgttgacct tggtacttgg
     4441 tggaaattca ttggtaaatt tattgtaatg gtgatgcttg taagcgtgct attacttgta
     4501 gttgcaacat tcttttaaca gataggaggt tcctatggaa tcctatatca cacctaaaca
     4561 tcaagaggcc tgtgtagctg ccattaaaca gatcgtttct tacccttctg tttgtcatga
     4621 aggagaaaat ggcacacctt ttggacaggc cattcaagat gttctcgaag caaccttaga
     4681 cttatgtcaa ggtcttggct tctatactta tattgatcct aaaggttact atggctatgc
     4741 tgagttaggt gaccaaaaag aggtcttggc tattctgtgc catttggacg ttgttccaga
     4801 aggagatcgt cagttatgga agacagagcc ttttgactgt gttgaggcag gcggctgttt
     4861 atttggtcga ggcactcaag acgataaagg gcctactatg atggcactat ttgccaccaa
     4921 agccttgata gatgcaggcg ttacctttaa taaacgcatt cgttttattt tcggaacaga
     4981 tgaagaaact ttgtggcggt gtatgaatcg ctacaatgat gtagaagaac aggctacctt
     5041 tgggtttgct cctgattcaa gtttcccttt aacctatgcc gaaaaaggcc tacttcaggc
     5101 aaaattagtg gggaaaggtt ctgataaact gtcacttgaa atcggacaag cctacaatgt
     5161 tgttcctgca agagcctctt atcaaggtga taagcttgag actttacaaa aagaactaga
     5221 taagcttggc tttgagtacg tcgtcaaaga gggagaatta acggtttatg gtctcgccca
     5281 acatgctaaa gatgctcccg atggcatcaa cgctatgatt aggcttgcca aagctttagt
     5341 ggtccttgaa cctaacaaaa cccttgattt tcttgctaat gtcattgatg aagatggcag
     5401 agcacttaat atttttggca gaatcgaaga tgaaccttca ggcaaattaa gctttaatgc
     5461 cgcagggctt accttaacca aagacaaggc agaaattcgc ctagatattc ggattccagt
     5521 tttggcagat aaggaaaaat tagtccaaca attaagccaa aaagcacaag aatacggcct
     5581 aacctatgaa gaatttgatt atttggcccc attatatgtg ccattagaca gtgaattggt
     5641 aacaaccttg ttatctgtct atcggaaaaa aacaggtgat caaagccctg cccaatcatc
     5701 aggaggagca acctttgcta gaacaatgaa gaattgtgtt gcctttggtg cccttttccc
     5761 tgatgctgtt caaacggaac accaagaaaa tgaacatatt gttttagcgg atgcttaccg
     5821 cgctatggat atttatgcgg aagctattta ccgactaacg caataacaag atatgaggag
     5881 taattatgac gaaacaaaaa atcgtagtcg cacttggagg aaatgctatt ctttcaacag
     5941 atgcgtcagc aaaagcacaa caagaagcct tgatgtccac atcaaaatca ttggttaaat
     6001 taatcaaaga aggtcatgaa gtcatcgtga cccacggcaa tggcccacaa gttggtaatc
     6061 tcttattaca acaagcagcg gcagattctg aaaagaatcc ggctatgcct ttggatactt
     6121 gtgttgctat gacagaaggt agcatcggtt tttggttagt taatgccctt gataatgaat
     6181 tgcaagccca aggtattcaa aaagaagtgg cagctgttgt cactcaagtg atcgtggatg
     6241 ccaaagaccc agcttttgaa aacccaacaa aaccaattgg tccatttctt accgaagaag
     6301 atgccaaaaa acaaatggcg gagtctggtg caagtttcaa agaagatgca ggtcgtggct
     6361 ggcgtaaggt tgtgccatca ccaaaaccag ttggtattaa agaagccaat gtcatcagaa
     6421 gtctcgttga ttctggcgtt gttgtggtta gtgctggtgg tggcggtgtg cctgttgtgg
     6481 aagatgcaac tagcaagtcc ctgactggtg tggaagctgt tattgacaag gactttgcta
     6541 gccaaaccct ttcagaattg gtggatgcag acctctttat cgttttgaca ggagttgaca
     6601 atgtttacat caacttcaac aaacctgacc aagccaaatt ggaagaagtg actgtctctc
     6661 aaatgaaaga atacatcaca caagaccaat ttgcaccagg tagtatgtta ccaaaagtgg
     6721 aagctgccat tgcttttgtt gaaaacaaac caaatgctaa agccattatc acatcgctcg
     6781 aaaatattga caatgtacta tcagcaaacg ctggaacaca aattatcgca gggtaatcaa
     6841 gaggattttt agttctgttt aaaagactca tttaatggta ttttctgaag agtacgactg
     6901 acataaagag ttgatactgt ttttaaagga aaagagtgtg ccataataaa aaacaataat
     6961 agtattagag aagactaatt ttattgagaa ttagcctttt cttttggctt tgataggtgt
     7021 ataataacca tactgttttt ttatttttca aaatattaga ataaacaaaa gtggacaacg
     7081 tataaagaga actgctaagt cgttgagttc attagtccca aaaagattac caaaaatgaa
     7141 ggaggagcta tgaagaaaag ttttattcat caacaagagg agatttcctt tgttaagaat
     7201 acgttcactc agtatttaat tgctaagtta gatgttgttg aagtgcaagg acccatttta
     7261 agtcgggtcg gggatggtat gcaagataat ttgtccggta ctgaaaatcc agtatctgtc
     7321 aatgtcttga aaattcctaa tgcaaccttt gaagttgtgc attcattagc aaaatggaaa
     7381 cgtcacacct tagcccgttt tgggtttaat gaaggtgaag gtcttgttgt taatatgaag
     7441 gctctccgac ctgatgagga ttcacttgac caaacccatt ctgtctatgt tgaccaatgg
     7501 gactgggaaa aagtcatccc tgatggcaaa cgtaatctcg cttaccttaa agaaactgtt
     7561 gaaaccattt acaaggtcat tcggctaact gaattagctg tagaagctcg ttatgatatt
     7621 gaggctgttt tacctaagaa aataaccttc attcataccg aagaattggt agctaaatac
     7681 cctgatttga cacccaaaga acgtgaaaat gccattacta aagaatttgg agcagtcttt
     7741 ttaattggta ttggcggggt tttacctgac ggtaaaccac acgatggccg cgctcctgac
     7801 tatgatgact ggacaacaga aactgaaaat ggctatcatg ggcttaatgg tgatattttg
     7861 gtttggaatg accaacttgg ttcagccttt gaattatcct caatggggat ccgtgtggat
     7921 gaagaggccc taaaacgtca ggtggaaatg actggtgacc aagaccgctt agcctttgat
     7981 tggcacaaat ctttgttgaa tggacttttc cctctaacga ttggtggagg aatcggtcaa
     8041 tcacgtatgg tcatgttttt gttgcgtaaa aaacatattg gagaagttca gacctccgtt
     8101 tggccccaag aagttcgtga tagctatgat aatattttat aagtaatcac atcattttgc
     8161 taagttttcc acttgtataa gagactttaa ataaatgatc agaaatattg aaaaaagaaa
     8221 tcatttttaa ggtttagagc tagaaatttg ctataataaa tgttatgaga gttgtatcag
     8281 gtgaatttgg tgggcgtcct ttaaagacgc tcgatggaaa gataacacgc cctacttcag
     8341 acaaagttag aggtgcgatt tttaatatga taggacctta ctttaatggt ggtcgtgttt
     8401 tagatttgtt tgcaggttca ggtggattag ccattgaggc tgtttctcgt gggatgtctg
     8461 ctgcagtttt ggttgagaag aatcgtaaag cgcaagctat tattcaagac aatattataa
     8521 tgactaaagc tgagaatcgg tttaccttgt taaaaatgga agctgagcga gctattgatt
     8581 gcttgactgg tcgatttgac ttagtctttt tagaccctcc ttatgccaaa gaaacaattg
     8641 tggcaactat tgaagcttta gcagctaaaa acttattgag tgaacaggtt atggttgtct
     8701 gtgagacaga taaaacagtc ttgttgccaa aagagattgc aacgttaggt atttggaaag
     8761 aaaaaattta tggaattagt aaggtaacag tttatgttaa ctaaaatagg actttataca
     8821 gggtcatttg atcctgttac aaacggtcat ctcgatattg ttaaacgggc aagtggccta
     8881 tttgatcaaa tatatgttgg gatttttgat aatcctacca aaaaaagcta ttttaaacta
     8941 gaagttcgta aagcaatgct tactcaagct ctggctgatt ttacaaatgt aattgtagta
     9001 acttcgcacg aacgtttagc tattgatgta gctaaagaat tacgagtaac tcacttgatt
     9061 agaggcttgc gaaatgcaac tgactttgag tatgaagaaa atttggaata ttttaatcac
     9121 cttttagctc caaatattga gaccgtctat ttgatatcaa ggaataaatg gcaggccctt
     9181 agctctagtc gtgtgagaga gctaattcat tttcagtctt ccttagaagg tttggttcct
     9241 cagtcagtta ttgctcaagt ggagaaaatg aatgaaaaga cttaacaaaa tcaaatggtg
     9301 gttagtgggt ctgctagctt taatctcttt gttgctagcg ttattttttc cgctacctta
     9361 ttatattgaa atgcctggag gcgcttacga tattcggact gtcttacaag tcaatggcaa
     9421 agaagacaaa cgaaaaggag cttaccagtt tgttgcagtg ggcattagtc gtgccagcct
     9481 cgctcagcta ttatatgctt ggctgacacc gtttactgaa attagtacag cagaagatac
     9541 aacaggcgga tacagcgatg ctgatttcct tcgaattaat caattttaca tggaaacatc
     9601 acaaaatgca gctatttatc aagctttatc cttagctgga aaaccagtta cattagatta
     9661 taaaggcgta tatgttttag acgtaaacaa cgaatctact tttaaaggaa cgttacactt
     9721 agcagatact gtaacaggtg taaatggtaa acagtttact agttcagcag aacttattga
     9781 ctatgtttct cacctaaaac taggggatga agttacggtt cagtttacga gtgataataa
     9841 gcctaaaaaa ggagttggcc gtattatcaa actgaaaaat gggaaaaatg ggattggcat
     9901 tgccttgact gatcatacaa gtgtcaattc agaagacaca gtgatcttta gtactaaagg
     9961 agtaggagga cctagtgctg gtctaatgtt tactcttgat atatatgatc aaataactaa
    10021 agaagattta cgcaagggcc gtacaattgc aggtacagga actattggca aggatggcga
    10081 agtaggagat attggtggtg caggtcttaa agtagttgca gcagctgaag ctggtgcaga
    10141 tatatttttt gttccgaata atcctgttga taaggaaatt aaaaaagtta atccaaatgc
    10201 tataagtaat tacgaagaag ccaaacgggc agccaaacga ctaaagacca aaatgaagat
    10261 tgttcctgtt acgactgttc aagaggcact ggtttatctt cgcaaataga ataactatga
    10321 atgtattata ttcacgctat taactcataa aaaaacggtt gaaccagata gacagatcct
    10381 tgaccagtct tttgggttca atcatttttt acataaaaca tatctaactt gacagcgtaa
    10441 aaaagatgtt ataaaagtct agtggtaaaa aggcaataga gaattgtgta aactttagtc
    10501 gattatctgg aaatagagca tactaaaaac acctagtgaa aattgatttt tttcactagc
    10561 tcatccaaga actttcgcag ataatcatga gtccattcca tgactttatt attctggaaa
    10621 gccttgcaat agacaagtta acgttataac aactaaatta aaaacttgag attgaaaaat
    10681 ccccataaac ttattttaca aggaggtaag gctatggtaa ccattaaaca agttgctgaa
    10741 gaagcaggtg tttctagatc aacagtctcc aggtatattt ctcaaaaagg atatgtatct
    10801 gatgatgcaa ggcataaaat caaagcagcg atagcaaaat tacattacac tccaaatgtc
    10861 ttggcgcagt cattgaagac gaaaaaaaat caactagtcg gtttattatt accagacatt
    10921 tccaatcctt tttttccgag gttagcaagg ggagcagaag aatatttaaa agaaaagggg
    10981 tatcgggtta tgctaggaaa tatttcagac agcgaagctc ttgaagaaga atacgtccat
    11041 gtccttcttc aaagcaatgc tgctggcatt attactaccc atgactttac aaagcggtat
    11101 cctactcttg ctattccagt tgtagtggta gatcgtgttg accaagagac ccagtacggt
    11161 gtcttttcag ataatagggc agggggctta ttggcggctc agactgtctg gcaagcaggg
    11221 gcgaaagaag ttctgttaat aagaggtccg ctggataatg ctgaaaacat taatgagcgg
    11281 tttgaagcta gcttttctta ccttcaaaaa caagacgtga ctatgtatgt gtgtgatagt
    11341 cagaattttg attttgaaaa tattcagcta gaagctagtt ccaacctcaa gtgttaccca
    11401 acaatagaca gtattatagc accttctgat atccatgcta ttgcttatat tcatgagctg
    11461 cattctcaag gtaaaaagat tcctcaagat gttcaaataa taggttatga tgacatttta
    11521 atgagtcaat ttatttatcc ttctttatcg actattcatc aatcctctta tttgatgggc
    11581 cgttatgccg ccgaattagt ttatactatt gctagtcaat taactgtgaa agcaaatcgg
    11641 attaaattgc ctgttcacta cgttgagcga aaaacaataa ggaaaagata agtaataata
    11701 ttagtccaga ttttagcagg tatgatgaag atttattggg atttaccttc tactttaaaa
    11761 gatgttatct gtccttactt tcatcgctat cagtcaaaac gcattcttat gcaactctta
    11821 accttaagct taaggtcttt ttgataacat agaggaatgt tacacgatga tgacgcaata
    11881 aagcctaaat atagtaattg tcgtgatttt atagctagtg agtaatgaga tagcaagtct
    11941 ctcatttact tacaaaagtc aaaaaatagt gtataatggt tgagttacag ataacactgc
    12001 aaaaaagata acaagtgtcc ataattatct aagactataa aggcgatata gacagatata
    12061 aaaaagatga cgaatcagtt atcactggac aattaaccga tttagttaca actaatggat
    12121 ttttcagaaa ggtgtcaaat gaaaaaagaa atttcgccag aaatgtacaa ctataataaa
    12181 tttccaggtc ccaaatttat tcattttgaa gagcaagtta aggctgaagg cattgatttg
    12241 ttactcttag aagatgttaa gaacgctttt gatacgacta gctttggtca acgttataca
    12301 gaagttctcc taaagtatga ctatattgtt ggcgattggg gaaatgaaca gcttcgtctt
    12361 aaagggtttt ataaggatag tgacgatatc aagaaaacga atcgcatctc acgtttagaa
    12421 gattatatta aagaattttg caattttggt tgtgcttatt ttgttttaga aaatcttcat
    12481 ccacaagata ttaaatttga agaggagcgc caaccaagac gaaagaaatc acctaaatca
    12541 aaatcaaatc gtcgcaagcc aaactattca aatcagcagc ccgcaacacc taagagtaaa
    12601 tcgaagcggg gatcaaaaga aaagcaacct gaaaaccaag cgtttaccag tcaaaaacgt
    12661 cgaagtaata ctaagcataa agaaaagtca aaacgtaatc agactagtca acttaatacc
    12721 aaaattagtc attttatcat cagaaagaaa gataaataat ccatgaaacc atcgatttat
    12781 agcttaacac gcgatgaact gatcgcgtgg gcagttgaac gcggccaaaa acagtttaga
    12841 gctactcaaa tttgggattg gctctataaa aaaagagttc aatcttttga ggagatgacg
    12901 aatatttcta aagattttgt ttctatttta aatgatagtt tctgtgtcaa tcctttaaaa
    12961 cagcgagttg tacaagaatc agctgatggt acagtaaaat atttatttga actgcccgat
    13021 ggtatgttaa ttgaaacagt tttaatgcgt caacattatg gtcattctgt ttgtgtgacg
    13081 actcaagttg gctgtaacat tggctgtact ttttgtgcta gtggattgat caaaaagcaa
    13141 cgtgatctaa acagtgggga aattacagct caaatcatgt tagtccaaaa atattttgac
    13201 gatagaaagc aaggtgagcg ggttagccat gttgtcgtaa tgggcattgg tgaacctttt
    13261 gataattaca aaaatgtcat gtgctttctt cgcgtcatca acgatgataa tggcttagca
    13321 attggtgccc gtcatattac agtctctacc tcagggttag ctcacaagat tcgggatttt
    13381 gcaaacgagg gagtacaggt taatttagca gtctcgttgc atgcaccaaa taatgattta
    13441 cgttcaagga ttatgcgagt aaatcgctct tttccgcttg aaaagctctt ttcagctata
    13501 gaatactata ttgaaaaaac gaatcgtcgt gtcacttttg aatacattat gctaaatgaa
    13561 gttaacgata gcattaagca agctcaagaa ttagcagact taactaaaac tattcgtaag
    13621 ttatcttatg ttaacttgat tccgtataat cctgtttcag aacatgatca gtatagtaga
    13681 agtcttaaag agcgagttct agcgttttat gatgtgctaa agaaaaatgg agttaactgt
    13741 gtggtgcgtc aagagcacgg aacagatatt gatgcagcct gtggccagtt acgttctaaa
    13801 acgatgaaaa aagatcgcga aaaggttaca gcgacaaaat aaagcccaaa aaatatcttt
    13861 gattgacaat gcttgatgac aaaatattcc tagtcactaa aatgactagg ttttttatct
    13921 ggcctaaaaa tgctctagaa gcacaatcca aaataatcca aaactaagat aaggaataaa
    13981 aggtatgcgc ttgatgccta atagtaagca agcagtaata cctgctaaac tagcaagttg
    14041 aattagccaa atcaacgacg ttagatccaa tactaaagct aagctagcaa ggtagaaaaa
    14101 atcgcctgct ccaattgaaa aaggtcttaa atgagctaat aaacctagta gcagtaatat
    14161 caatgataaa taattgatcg aataaaacag gagtagactt acaaagctaa aaagccacaa
    14221 gataaaaggg tattcttgag aacgccaatc aaataaacta aataataaag aaaagagtaa
    14281 caagtaacag taactagcac taacccaatg taccatacta gcccataaga taattattag
    14341 acttatctct aagctaaaga agattttttg gctagttata aaatggtttt ggaactgccg
    14401 aaaaacgcgt ttggcaaaag ttagttggtc acaaacaatg acagtctgtt tacttagctg
    14461 ttcttgacca ttatcaggaa aataaagtag taaacagtaa aaaagatggg tcaataagat
    14521 gcccgaacat atactaaaaa aagctatcat acttatttat tcgaaaagaa atcaaatact
    14581 tgcaatcttt ccttaatcat tgtagaatat agatataaaa cgataatgat tctaattaag
    14641 tgtctaatca tccaattagg attattccgt tattgtcgaa taggattagg tccttaaccc
    14701 tttcttatgt ttatcacgtt agggttagtt ccccctccat tcttgccctt taagctgaaa
    14761 agtaaggaga tgttattatg acaaacacac tcgttgaaaa tatttatgct tcagtaactc
    14821 acaatatttc taaaaaagaa gcatcaaaaa atgaaaaaac taaagctgtt ttaaaccaag
    14881 ctgtcgctga cttatctgtg gctgcatcta ttgtgcacca agtacactgg tatatgcgtg
    14941 gtccaggttt cttgtacctt cacccaaaaa tggatgaatt acttgatagc ttgaatgcta
    15001 atttagatga aatgagcgag cgtttgatca ctattggcgg agcgccttat tctaccctag
    15061 ctgagttttc taaacactct aaattggacg aagcaaaagg tacttacgat aaaacagttg
    15121 ctcagcattt agcaagattg gtcgaagttt acctttacct cagcagcctt taccaagttg
    15181 gtttggatat taccgatgaa gaaggcgatg ctggaacaaa tgatttgttt acagcagcta
    15241 agacagaggc tgaaaaaacc atttggatgc tccaagcaga gcgtggacaa ggcccagcac
    15301 tctaattgat tatgccttag gataaaagaa gtcaatgata aaattggctt cttttttatg
    15361 gaatcatcga ttcattttca gaaacataga aagcgattcc atacttgtct tgaaatttgc
    15421 cgtagaattt gctaaaatct acttatatga aaacactata tgatgtgcaa caattgctaa
    15481 aaaactttgg catttttgtt taccttggca aacgtctcta tgatattgaa atgatgaaga
    15541 ttgaacttca gcgtctctat gatagcggct tattggataa gagggattac ttaaatgcgg
    15601 agttaatttt gcgacgtgag catagattag aattggaaaa agaaggatag acaaatgagt
    15661 caaaaattac tggggattga tttaggtggt accaccatta aatttggaat tttaacagca
    15721 gcaggagaag tccaagaaaa atgggcaatt gagactaata ttttagaagg aggcaagcat
    15781 attgttcccg atattgtagc ttccatcaaa catcgcttag acttgtatgg tctaagcagt
    15841 gctgattttg tgggaattgg tatgggatca ccaggagcgg ttgaccgtga tactaataca
    15901 gttactgggg cattcaacct taattggaaa gaaacccaag aagtcggttc cgttgttgaa
    15961 aaagaattgg gcattccttt tgccattgac aatgatgcta atgtggctgc ccttggtgaa
    16021 cgttgggtag gtgctggtga aaataaccca gatgtcgtct tcatgacact tggaacaggt
    16081 gtcggtggag gcattattgc tgatggtaac ttgattcatg gtgttgcagg agcaggtggt
    16141 gaaatcggcc acatgattgt tgagccagaa aatggctttg cttgtacttg tggctcacac
    16201 ggctgtttgg aaacagtagc ttcagcaaca ggagttgtca aagtggcacg tttattggca
    16261 gaagcttatg aaggggattc agccatcaaa gcagctattg acaatggtga aggtgttacc
    16321 agcaaagata tttttatggc agctgaagca ggggattcct ttgctgattc tgttgtggaa
    16381 aaggttggtt actaccttgg ccttgcttca gcaaatattt ccaatatatt gaatccagac
    16441 tcagtggtta tcggtggggg tgtgtcagca gcaggagaat ttctacgctc acgtattgaa
    16501 aaatactttg tgaccttcac tttcccacaa gtgaggtatt caactaaaat taagattgca
    16561 gagcttggca atgatgctgg aattatcggt gcagctagcc ttgctcgaca atttatcaca
    16621 aaataggagg gggatatgtc tccaatcaca cttatcttat ggttacttct tgtcggcatt
    16681 gctggttact acacatggaa ctatttctct tttcgaaaaa tggcaaagca ggttgataac
    16741 gagactttta aagacgtgat gcgtcaaggt caattgattg atttacgaga gccagcggct
    16801 tttagagcta agcatatttt aggagctcga aattttccag cgcaacaatt tgatgctgct
    16861 attaagggac tacgcaagga caaacctgtt cttatttacg aaaatatgcg tccccagtac
    16921 cgtgtgcctg cggtcaaaaa acttaaaaaa gctggctttg aagacgttta tgtcttaaaa
    16981 gacggtattg attattggga tggcaaagtt aaacaaacaa cctagttaag agtaacgtgg
    17041 agttaagggg aataaaggca gtcactgtct caaaaacctt aattcctttt ttgctgtatc
    17101 cagacttgct gaaagtctga aaacatttac aattgattaa aaccagtttt ttaaaacatt
    17161 ttgtgttata cttatctagt taaaatatat ttacttagag gaacaaatga ctaacttaag
    17221 aaacgatatc cgtaacgtag cgattattgc ccacgttgac cacggaaaaa caacacttgt
    17281 agatgaatta ttaaaacaat cccatactct tgatgagcgt aaagagcttc aagagcgtgc
    17341 catggattcc aatgaccttg aaaaagaacg tgggattacg atccttgcga aaaatacggc
    17401 agtagcctat aacgatgttc gtattaacat catggatacc ccaggacacg cggacttcgg
    17461 tggtgaagtt gaacgtatca tgaaaatggt tgacggggtt gttcttgttg tggatgccta
    17521 cgaaggaaca atgccccaga cgcgtttcgt attgaaaaaa gcacttgagc aaaaccttat
    17581 cccgatcgtt gtggtgaaca agattgacaa accttcagct cgtccagcag aagttgtaga
    17641 tgaagtgctt gaattattca tcgaacttgg tgccgatgat gagcaattgg aattcccagt
    17701 tgtttacgca tcagctatta atggaacatc atcattatca gatgaccctg ctgaccaaga
    17761 gcatactatg gcaccgatct ttgatacgat tattgatcat attccagcgc cagttgataa
    17821 ttcagatgag cctttgcaat tccaagtgtc acttttggac tacaacgatt tcgtaggtcg
    17881 tatcggtatc ggtcgtgttt tccgtggtac tgttaaagtg ggtgaccaag tgactctttc
    17941 aaaacttgat ggtaccacta aaaacttccg tgttacaaaa ctgtttggtt tcttcggttt
    18001 ggaacgtcgt gaaattcaag aagctaaagc aggtgacttg attgctgttt caggtatgga
    18061 agatatcttt gttggagaaa ccattacacc aactgactgt gtggaagctc tgccaattct
    18121 tcgtattgat gagccaacgc ttcagatgac tttcttggtc aataactctc cttttgcagg
    18181 tcgtgaaggt aaatggatca cgtcacgtaa ggttgaagaa cgtcttttag cagaattgca
    18241 aacagacgtg tcacttcgtg ttgacccaac agattcgcca gataaatgga cggtttcagg
    18301 gcgtggagaa ttgcatttgt caattcttat cgaaaccatg cgtcgtgaag gctatgaact
    18361 tcaagtatca cgtccagaag ttatcatcaa agaaattgat ggtgtcaaat gtgaaccgtt
    18421 tgagcgtgtt caaattgata caccagaaga atatcagggt gcaatcatcc agtctctttc
    18481 agaacgtaaa ggggatatgc ttgatatgca gatggttggt aatggtcaaa cgcgtttgat
    18541 tttcttgatt cctgcacgtg gtttgattgg ttattcaaca gagtttcttt caatgacacg
    18601 tggatatggt atcatgaatc atacttttga tcagtatcta ccggttgttc aaggagaaat
    18661 tggtggccgt catcgtggtg ccttggtttc tattgaaaat gggaaagcaa cgacatattc
    18721 aatcatgcgt attgaagaac gtggaactat ctttgtcaac ccgggtacag aagtttacga
    18781 agggatgatt gttggtgaaa actcacgtga taacgacctt ggtgttaaca ttacaacagc
    18841 taagcaaatg acaaatgtcc gttcagcgac taaagatcaa actgcagtta tcaagacgcc
    18901 tcgtatccta acgcttgaag aatcattaga gttcttgaat gacgacgaat atatggaagt
    18961 aacgccagaa tctatccgct tgcgtaaaca aatcttgaat aaagctgcgc gtgataaagc
    19021 taataaaaag aaaaaatcag ccgaatagct tttgaagtta aactaactaa ataaaatagc
    19081 aaaaagatat ttaagaaaag tcatttttta aaggtctttt tgtgtttaca agttcctatg
    19141 gaatataaac caaaataaag gaggacggaa tgttttacct tattatggct gtcttgatta
    19201 tatcttatta tctatacatg gctcctaaaa gtgtccgtaa cacccttggg atgattggtt
    19261 tagttggctt ggttgctctg cttattgttt tagcgggctt gagttttatc aaaatcatgc
    19321 aaatccctcc tgaatttttt attgggatgg gaatggtggc attgggctat tttgctttaa
    19381 aagatgtgcg taaaatgacc aaaaaaccga gagttaaata aaaatactta aagattgatg
    19441 attttggttt ttatacgata aaaggactga tttgttttag acaatatcag tcctctttta
    19501 atagttcatt ttttctgaaa gaaagccttt agccgatttt cattgagtgt gcaactaaaa
    19561 agagatgctt ggtagtgaca gttaagacct ctgactagta ttttatctta ttttacttaa
    19621 aaaaacgtac caataatctc acaaatatgg gcatgatgtt tgtatattgg aaacggattc
    19681 taattctaaa ctcaagaacg gtatttttaa aatgttgaaa aagcatctaa ataaaggtaa
    19741 aatagaaatc aaatagaatg gatagtgtga gcttagatga aagtgataag taattttcaa
    19801 aacaaaaaaa tattaatatt ggggttagcc aaatcgggcg aagcagcagc aaaattattg
    19861 actaaacttg gtgctttagt gactgttaat gatagtaaac catttgacca aaatccagcg
    19921 gcacaagcct tgttggaaga ggggattaag gtcatttgtg gtagccatcc agtagaatta
    19981 ttagatgaga actttgagta catggttaaa aaccctggga ttccttatga taatcctatg
    20041 gttaaacgcg cccttgcaaa ggaaattccc atcttgactg aagtagaatt ggcttatttc
    20101 gtatctgaag cgcctattat cgggattaca ggatcaaacg ggaagacaac cacaacgaca
    20161 atgattgccg atgttttgaa tgctggcggg caatctgcac tcttatctgg aaacattggt
    20221 tatcctgctt caaaagttgt tcaaaaagca attgctggtg atactttggt gatggaattg
    20281 tcctcttttc aattagtggg agtgaatgct tttcgccctc atattgctgt catcactaat
    20341 ttaatgccga ctcacctgga ctatcatggc agttttgagg attatgttgc tgctaaatgg
    20401 atgattcaag ctcagatgac agaatcagac taccttattt taaatgctaa tcaagagatt
    20461 tcagcaactc tagctaagac caccaaagca acagtgattc ctttttcaac tcaaaaagtg
    20521 gttgatggag cttatctgaa tgatggaata ctctatttta aagaacaggc gattatagct
    20581 gcaactgact taggtgtccc aggtagccac aacattgaaa atgccctagc aactattgca
    20641 gttgccaagt tatctggtat tgctgatgat attattgccc agtgcctttc acattttgga
    20701 ggcgttaaac atcgtttgca acgggttggt caaatcaaag atattacctt ctacaatgac
    20761 agtaagtcaa ccaatatttt agccactaaa aaggctttat caggttttga taacagtcgc
    20821 ttgattttga ttgctggcgg tctagatcgt ggcaatgaat ttgacgattt ggtgccagac
    20881 cttttaggac ttaagcagat gattattttg ggagaatccg cagagcgtat gaagcgagct
    20941 gctaacaaag cagaggtctc ttatcttgaa gctagaaatg tggcagaagc aacagagctt
    21001 gcttttaagc tggcccaaac aggcgatact atcttgctta gcccagccaa tgctagctgg
    21061 gatatgtatc ctaattttga ggttcgtggg gatgaatttt tggcaacctt tgattgttta
    21121 agaggagatg cctaatgcct aagaagattt tatttacagg tggtggaact gtaggtcatg
    21181 tcaccttgaa cctcattctc ataccaaaat ttatcaagga cggttgggaa gtacattata
    21241 ttggtgataa aaatggcatt gaacatacag aaattgaaaa gtcaggcctt gacgtgacct
    21301 ttcatgctat cgcgacaggc aagcttagac gctatttttc atggcaaaat ctagctgatg
    21361 tttttaaggt tgcacttggc ctcctacagt ctctctttat tattgccaag cttcgccctc
    21421 aagccctttt ttccaaaggt ggttttgtct cagtaccgcc agttgtggct gctaaattgc
    21481 ttggtaaacc agtctttatt catgaatcag atcggtcaat gggactagca aacaagattg
    21541 cctacaaatt tgcaactacc atgtatacca cttttgagca ggaagaccag ttgtctaaag
    21601 ttaaacacct tggagcggtg acaaaggttt tcaaagatgc caaccaaatg cctgaatcaa
    21661 ctcagttaga ggcggtgaaa gagtatttta gtagagacct aaaaaccctc ttgtttattg
    21721 gtggttcggc aggggcgcat gtgtttaatc agtttattag tgatcatcca gaattgaagc
    21781 aacgttataa tatcatcaat attacaggag accctcacct taatgaattg agttctcatc
    21841 tgtatcgagt agattatgtt accgatctct accaaccttt gatggcgatg gctgaccttg
    21901 tagtgacaag agggggctct aatacacttt ttgagctact ggcaatggct aagctacacc
    21961 tcatcgttcc tcttggtaaa gaagctagcc gtggcgatca gttagaaaat gccacttatt
    22021 ttgagaagag gggctacgct aaacaattac aggaacctga tttaactttg cataattttg
    22081 atcaggcaat ggctgatttg tttgaacatc aggctgatta tgaggctact atgttggcaa
    22141 ctaaggagat tcagtcaccg gacttctttt atgacctttt gagagctgat attagctccg
    22201 cgattaagga gaagtaaatg gcaaaagata aagagaaaca aagtgatgac aagctcgttt
    22261 tgacagagtg gcaaaagcgt aacattgaat ttttaaagaa aaagaagcag caagctgagg
    22321 aagaaaaaaa actcaaagag aaattattga gtgataaaaa agcgcagcag caagctcaaa
    22381 atgcttctga agcagttgag cttaaaactg atgagaaaac tgatagtcag gaaattgagt
    22441 cagaaacgac gtcaaaacct aaaaaaccca aaaaagttag acaacccaag gaaaaaagcg
    22501 cgacacaaat cgcttttcaa aaatccttgc ctgttctttt gggggcgctc ttacttatgg
    22561 cggtgtctat ttttatgatc actccttata gcaaaaagaa agagttttct gtaagaggaa
    22621 accatcaaac gaaccttgac gaattaatca aagctagcaa agtcaaagca tctgactatt
    22681 ggttaacgtt gttaacttcg cctggtcagt atgaacgacc gattcttcgt actattccat
    22741 gggtgaaatc tgtacatctc tcttaccaat ttcctaatca ctttctattt aacgttattg
    22801 aatttgaaat catcgcttat gcacaagtcg aaaacggttt tcagcctatt ttggagaatg
    22861 gaaaacgtgt ggacaaggtc agggcatcag aactaccgaa atctttcttg attcttaatt
    22921 taaaagatga gaaagcgatc caacagttag ttaagcaatt aacgacatta cctaaaaaat
    22981 tagtcaagaa tatcaagtca gtgtctcttg caaattccaa aacgacagcg gatttactac
    23041 ttattgaaat gtatgacggt aatgtagtta gagtaccgca gtcacaactc acattgaaac
    23101 ttccctatta tcaaaaattg aaaaaaaacc ttgaaaatga tagtatagtg gatatggaag
    23161 ttggaattta tactacaaca caggagattg aaaatcaacc tgaagttcct cttacgccag
    23221 aacaaaacgc agctgataaa gaaggagata agcctggtga acatcaggaa cagacagaca
    23281 atgattcaga aacgccagca aatcagagta gtcctcagca agcaccacca tccccagaaa
    23341 cggtcctcga acaggcccat ggctagctaa tatctaagtt gaaaaagcaa tgaaaacgtt
    23401 agaaattcaa cgattctaac ccataatgaa ttgcctaaaa aaaattaagt ttatataaca
    23461 aaaaacgtaa aatgataaca ttttacgttt ttttatggta taatattttc tgaatgattc
    23521 tgttttttag cagtttttag aatagcaaaa gtttggaaag taagtgaggt caagtgaatg
    23581 gctagaaatg gcttttttac tggtttggac attggaacaa gctcgataaa agttttagta
    23641 gcagaattta tttctggtga gatgaacgtc attggtgtta gtaatgttcc aagtaccggc
    23701 gtaaaagatg gcataataat cgatatagag gcagctgcga ctgccatcaa aactgcggta
    23761 gaacaagcag aagaaaaagc agggatgaca attgaaaagg ttaatgttgg gctaccggca
    23821 aaccttcttc aaattgaacc aacacaagga atgattcctg tcccaagtga gtctaaagag
    23881 ataaaagacg aggatgttga tagcgttgtt aaatcggctt taacaaaaag tatcacacca
    23941 gaacgagagg ttatctcttt agttccagaa gagttcattg tggatggctt tcagggcatt
    24001 cgagatccac gtggtatgat ggggattaga ttagagatgc gcgggcttat ttatactgga
    24061 ccaagcacca ttttacataa tctgcgtaaa acggtagaaa gagcaggcat taaagttgaa
    24121 aacatcatta tttctccgtt agctatggct aaaaccattt taaacgaagg tgagcgcgag
    24181 tttggagcta ctgtaattga tatgggaggt ggacagacaa ctgtcgcttc tatgcgagca
    24241 caagaattgc agtataccaa tatatatgct gaaggcggcg aatacattac taaagatata
    24301 tcaaaagtat taaaaacgtc tttggctatt gcagaagcac ttaagtttaa ttttggtcaa
    24361 gcggagatat cagaagctag tataactgaa acagtaaaag ttgatgtggt aggtagtgaa
    24421 gagcctgttg aggtaactga acgttattta tctgaaatta tttcagcgcg tattcgtcat
    24481 attttagatc gtgtgaagca agatttggaa agaggtcgtt tactagactt accaggaggc
    24541 attgttttga ttggtggcgg tgcaatcatg cctggagtgg tagaaattgc acaagaaatc
    24601 tttggagtaa ctgtaaagct ccatgttcca aatcaagtcg gtattagaaa tccaatgttt
    24661 tcaaacgtta tcagtttggt agaatatgtt ggtatgatgt ctgaagtaga cgttttagca
    24721 caaactgcag tttcaggaga agaacttttg cgacgcaagc ctattgattt cagtggtcaa
    24781 gaatcttatt taccagatta tgatgattca agaagaccag aatcgaccat tggctatgaa
    24841 caacaagcgt cacaaacagc atatgattca caagttccga gtgatcctaa acaaaaaatt
    24901 tcagaacgtg ttcgtggcat atttgggagt atgtttgatt aaaagtaata aagtgaggaa
    24961 ataaaatggc attttcattt gatactgcat caattcaagg tgcaattata aaagtaattg
    25021 gagtcggcgg aggtggcgga aatgccatta atcgtatgat tgatgaaggt gttgctggtg
    25081 ttgagttcat cgcagcaaat acagacattc aggcattaag ctcatcaaaa gctgaaacgg
    25141 ttattcaact aggccctaaa ttaactcgtg gacttggtgc tggaggacaa cctgaagtag
    25201 gacgtaaagc tgctgaagaa agcgaagaaa ttttaacaga agctcttaca ggagcggaca
    25261 tggtatttat tactgccggt atgggtggtg gctctgggac aggggctgca ccggttattg
    25321 ctcgtatcgc taaaagtttg ggagccttga cagtagctgt tgttactcgc ccgtttggtt
    25381 ttgaaggtaa caaacgtggt aattttgcta ttgaaggtat cgaagaacta cgtgaacaag
    25441 ttgatacttt gttaattatt tcaaataata accttcttga gattgttgat aaaaagacgc
    25501 ctttattaga agcacttagt gaagctgata atgttttacg tcagggagtt caagggataa
    25561 ccgacttaat tactagtcct ggccttatca atctcgattt tgccgacgtg aaaacagtta
    25621 tggcaaataa agggaatgcc ttgatgggga ttgggattgg ttctggagaa gagcgcattg
    25681 ttgaggcggc gcgtaaggca atctattcac ccctattaga aacgactatt gatggtgcac
    25741 aagacgttat tgtaaacgtt acaggaggtc tcgacatgac acttacagaa gctgaagaag
    25801 cctctgaaat tgttgggcaa gctgctggtc aaggcgttaa catttggtta ggaacatcta
    25861 ttgatgatac tatgaaagat gacatccgtg tgactgttgt agcaactgga gtgcgccaag
    25921 aaaaagccga gcaagtttca ggttttcgtc agcctaggac ttttacccaa accaacgcgc
    25981 agcaagtagc gggtgcacaa tatgcatcag atcaagcaaa acagtcggtt caaccagggt
    26041 ttgatcgtcg ctcaaatttt gattttgaca tgggggagtc tcgcgagata ccaagtgcac
    26101 aaaaggtaat ttctaatcat aatcaaaatc aaggttcagc ttttggaaat tgggatttga
    26161 gacgtgataa tatttctcgt ccaacagaag gtgaattgga taaccatctt aatatgtcaa
    26221 cgttctcagc taacgatgac agtgatgatg aattagaaac gcctccattc tttaaaaacc
    26281 gttaataatg gatttactga caaataaaaa gaagattttt gagactatcc gcttatctac
    26341 agaggcagca aataggacta atgatagtgt ttcagttatt gctgtaacaa aatatgtgga
    26401 tagtacaatt gcaggtcagc ttatcgaagc aggaattgag cacattgccg aaaaccgtgt
    26461 tgataaattt cttgaaaagt atgatgcgtt aaagtgtatg ccagtaaagt ggcatttgat
    26521 cggtacctta caacgtcgta aggttaagga agttatcaat tatgttgatt attttcacgc
    26581 tctagattct gtgagattag ctttggaaat caacaagaga gctgaccatc ctgtgaagtg
    26641 ttttctacaa gttaatattt ctaaagaaga gagtaaacat ggttttaaca tttctgagat
    26701 tgatgaagcg attgaagaaa taggtaagat ggagaagata cagttagttg gtttaatgac
    26761 tatggcacca gcaaatgcca gtaaagaaag tattataact atttttcgac aagcaaatca
    26821 attaagaaaa aacttgcagt taaaaaaaag aaagaatatg ccttttacag aattgagcat
    26881 gggcatgagt aacgattatc caattgctat tcaagaaggc tcaactttta ttcggattgg
    26941 tagagctttc tttcactaat ggagaataag atggctttta aagatacatt taacaagatg
    27001 atttcttatt ttgacacgga tgaggttaac gaagttgaag aagatgttgc agcatcaact
    27061 gataacgtta ttccaagatc acaacaatca gtcagagcaa gtagtcatcc aaaacaagaa
    27121 cctagaaaca atcacgtaca acaagatcat caagcgagat cccaagaaca gacaaggtca
    27181 caaatgcatc caaaacatgg tacttctgaa cgctattatc agcagtctca gccaaaagaa
    27241 ggccatgaaa tggttgacag aagaaaacgg atgagcactt ctggtattgc aaatcgccgt
    27301 gagcagtatc aacaatcaac ttgttcagat caaacaacta ttgccttaaa gtatcctcgt
    27361 aaatatgagg atgctcaaga aattgtggat cttttaatag ttaatgaatg cgttttgatt
    27421 gattttcagt ttatgctaga tgctcaggct agacggtgtt tagattttat tgatggtgct
    27481 agtaaagtgc tctatggtag cttacaaaag gtaggctctt caatgtactt actggctccg
    27541 tcaaatgtat ccgtcaatat agaagaaatg actatcccac atactacaca agatattggc
    27601 tttgattttg atatgaaaag gcggtaaata aatgatatta atactatcta ttcttcttcg
    27661 tctgatcaaa gtttacactt atttattgat tgcttacgca ctaatgtcat ggtttcctgg
    27721 ggcatatgat tcaaaaattg ggcgtttgat tagtggtatc gttgaaccaa ttttaaaacc
    27781 ttttagagca tttaatttac aatttgccgg tcttgacttc actatttttg tcgtcattat
    27841 tagtttgaat tttttagctc aagttttggt ccgtgtgttt atttaatggt tagtcatagt
    27901 aagatttatc agcattttca ccaagaagaa tatcctttta ttgatagaat gtctgatatg
    27961 attaatagag ttgaagatta ctatctttta gaagttactg agtttttaaa tcctagagaa
    28021 gtgatgattt taaaaagttt gattgcttta acagatctaa aaatgttcgt atcaacagat
    28081 tactatccaa gcgaatatgg tcgtgttatt attgcacctg gttactatga cttagaacaa
    28141 agtgattttc aaatagcttt agtagagata agttatcagg caaagtttaa tcagttgaca
    28201 catagtcaaa ttttaggaac tttaattaat gaattaggag taaagcgaaa tttatttgga
    28261 gatgtttttg ttgaaatggg atatgcccag ctcatgatta agcgggagtt attggattat
    28321 tttttaggaa caattactaa aatagctaaa actagtgtga aattaagaga agttaacttt
    28381 gatcagttaa ttaggtctat tgataacagc cagaccctgg atattctagt ttctagtttt
    28441 cgattagatg gtgtagttgc tactatctta aaaaaatctc gaacgcaagt tatagcatta
    28501 attgaagcaa ataagattaa ggtaaactat cgactcgcta ataaagcttc agataatcta
    28561 gtcatagggg atatggtgag tatcagaggt cacgggcgtt ttactctttt agcagataat
    28621 ggagtgacca aacatggcaa acaaaaaata acactaagta aaatgataca taaataagga
    28681 gatacaatgg cacttacaac gctagaaatt aaagataaaa cttttaagac aaaattccga
    28741 ggatactgtg aagaagaagt caatgaattc cttgatattg ttgttgatga ttacgaagct
    28801 cttgtacgta aaaatcgtga taacgaagca agaattaaag atcttgaaga aaaattatct
    28861 tactttgatg aaatgaaaga gtcacttagc cagtctgtaa tcttagctca agaaacagct
    28921 gaaaaagtga aagcaacggc taatgcggaa gcaacaaact tggttagtaa agcgacttat
    28981 gatgctcagc atttattaga tgaatctaaa gctaaagcca atcaaatgtt gcgtgatgca
    29041 actgatgagg ctaagcgagt tgcgattgaa acagaagaat taaagcgtca aacacgtgtg
    29101 ttccaccaac gtttaatctc atctattgag tcacaattaa gcttatcaaa ttcacctgaa
    29161 tgggatgaac tgttacaacc gactgcaatc tatcttcaaa attctgacga tgcttttaag
    29221 gaagtcgtga agaccgttct taatgaagac attcctgaat ctgatgatag tgcctctttt
    29281 gatgcaacac gtcagtttac tccagaagag ttagaagaat tgcaacgtcg tgttgatgaa
    29341 agcaataagg agttagaggc ttaccaactt gactctcaat ctgattctac gactgagcca
    29401 gaggtaaatc tcagtgaaac acaaacgttt aaattaaata tctaaataaa gaaaaacaag
    29461 atgatttgct tataatcaca gcaagcggga gatgatgaga gtctcgtatt ccctaagtat
    29521 tatcattatc attttctaaa attttcgctg aactacagta agcgaggagg tttgttcacc
    29581 ttacgagcaa agagggagcg gtaagtctta tgatatatta tcgctctgaa ctaaggtggt
    29641 accacgagct ttcgtccttt ttgagacgag gcttttttcg ttatagtcgc aagtttgttt
    29701 aaaaggagtt tgaaataatg aaattaaaag agacacttaa tctaggaaaa acagcctttc
    29761 caatgcgcgc aggtcttcct aataaagagc cacaatggca agcagcttgg gaacaagcag
    29821 agctttacaa aaaacgtcaa gaattgaatg caggtaagcc tgcctttcat cttcatgatg
    29881 gacctccata cgctaacggc aatattcacg ttgggcatgc ccttaataaa atttcaaaag
    29941 atatcattgt gcgttctaag tccatgtctg gctttcaagc gccttatgta cctggttggg
    30001 acacacacgg ccttccaatc gaacaagtct tggctaagca aggaatcaaa cgtaaggaga
    30061 tggatttagc agaatacctt gagatgtgtc gtcaatacgc tttaagtcag gttgataaac
    30121 agcgagatga tttcaaacgg ttaggtgttt cggcagactg ggaaaatcct tatgtcactt
    30181 tggacccaca gtttgaagct gatcaaattc gtgtttttgg agcgatggct gaaaaaggtt
    30241 acatctatcg tggtgctaaa cctgtttatt ggtcatggtc ttcagaatcg gccttggcag
    30301 aagctgaaat tgaataccat gacattgatt caacctcttt atactacgcc aataaagtta
    30361 aagatggcaa aggcatcctt gatactaata cgtatatcgt tgtttggaca acaacaccat
    30421 ttacggttac agcatcacgt ggtttgactg ttgggcctga tatggattat cttgtggtga
    30481 aacctgctgg ttcagaccgt caatatgttg tggcagaagg tcttttggat agccttgctg
    30541 gaaaatttgg ctgggaatct tttgaaactt tagccagcca taaaggagct gatttagagt
    30601 acattgtgac agaacaccca tgggatactg acgtagaaga attggttatc cttggtgacc
    30661 atgttaccct tgagtcaggg acagggattg tccacacagc accaggtttt ggtgaggatg
    30721 actacaatgt tgggacaaaa tacaaactgg aagttgctgt gactgttgat gaacgtggcc
    30781 taatgatgga aaatgcaggt ccagatttcc acggacaatt ttataacaag gtaacgccga
    30841 ttgtcattga taaacttggt gatcttttat tggcacaaga agtgatcaat cactcttacc
    30901 catttgactg gcggacgaaa aaaccaatca tctggcgtgc tgtaccgcaa tggtttgctt
    30961 ctgtttctga tttccgtcaa gatattttgg atgaaattga aaaaacaacc ttccatccat
    31021 catggggtga aacacgcctt tacaatatga ttcgtgatcg tggcgactgg gttatttctc
    31081 gtcaacgtgc ttggggagtt ccgcttccta tcttctatgc cgaagatggc acagctatta
    31141 tgactaaaga agtgacagat catgtggctg atttgttcca agaaaatgga tcaatcattt
    31201 ggtggcaaaa agaagctaaa gacctattac cagagggctt cactcatcca gggtcaccaa
    31261 atggcgagtt tacaaaagaa actgatatca tggacgtttg gtttgactct ggttcttctt
    31321 ggaatggagt catgaatgct agagaaaatc tttcctatcc agcggatctc tacttagaag
    31381 gctctgacca gtatcgtggt tggttcaatt catccttaat tacatctgtg gctgttaatg
    31441 ggcatgctcc atataaggct attttatcgc aaggctttgt tcttgatggt aagggcgaaa
    31501 aaatgtctaa atcaaaaggc aatatcattt ctccaaatga tgtggctaaa caatatggtg
    31561 cagatattct ccgtctctgg gtagcttctg tggataccga taatgatatt cgtgtttcta
    31621 tggagatcct tggtcaagtc tctgaaactt accgtaaaat ccgtaacacc cttcgcttct
    31681 tgattgctaa tacatctgat ttcaaccctg ctacggatac agtagcttat gcagacttag
    31741 gagctgttga taagtacatg acaattgtct ttaatcagtt ggtagcaacg attactgacg
    31801 cttatgagcg ttatgacttt atggctattt acaaagcagt ggtgaacttt gttacggttg
    31861 atttatcagc cttctatctt gattttgcta aagacgttgt ctatattgaa gctgccaata
    31921 gcttagaacg tcgtcgcatg cagacagtct tctatgatat cttggttaag attaccaagt
    31981 tattgacgcc aatcttgcct cacaccactg aagaaatctg gtcttatcta gaatatgagt
    32041 cagaagcatt tgttcaattg gcagaaatgc ctgtggcaga aactttctca gctcaagagg
    32101 atattttaga agcttggtct gctttcatga ctttgcgtac ccaagctcaa aaagctttgg
    32161 aagaagcgcg aaatgctaag attatcggta aatcattgga agcccatttg accatctacg
    32221 ctagtgaaga agtgaaaacc ttattgactg ctttagacag cgatattgct ttgcttttga
    32281 tcgtgtctca attaaccatt gctgacttgg cagatgcgcc tgcggatgca gtggcatttg
    32341 aaggtgttgc ctttatggta gaacatgcca taggtgaagt ttgtgagcgt tcacgccgca
    32401 tcgacccaac tactcgcatg cgttcttaca atgcatttgt ctgtgatcac agcgctaaaa
    32461 tcattgaaga aaatttccca gaagctgtgg ctgaagggtt tgaagagagt ggcaaataag
    32521 tcttatcaag acttgaagtg acactgagta agaagacaac catcgggtct taggacctga
    32581 tggtttttta gtagagctga ttacgtccat tagccagctt taacgagaga caaagtagga
    32641 gaaatttaga ctactttttt tatttctttt aagaaaattg ctggcttcat ataaggacta
    32701 ttaagataga gttcaccttt cgctaataaa aaacttagct cttttagaag ggctaagttt
    32761 tgtctgaata gctggctgct gtttatacag aagtttgaaa tgaaatttca ataaggttat
    32821 tcgtgtgaag tgtttttgat tgtccaggaa taacaatttt aggatcaatt ttacgtttta
    32881 aaaaaaattc gcgaatgata tcaagttcat cctccttgat ggcacggtat ttatttgaaa
    32941 taagtagttc gtaatgtttt ggtgcttggg taaaaatgac atctgtattt cctgctgagt
    33001 atacttcgac taaataggca tcggtgtttt ttagctgatt tctgatgagt tctgggtgac
    33061 tgctagtggt attgatgagt ctcataaatg tcctccttag tattcctgta cctattatag
    33121 cactaattta aagccttagt tagtagaatg atgctttttt tgccattcct tgactcccca
    33181 ttgatggctc tcccgtttta atttagcaat tgcctctata ggagaaaacc aacctaagtt
    33241 attaaaatct tctaagggct tagaaacagc ttgaaatgca gttacttcat aaagataggc
    33301 aggatggtag aagtgggtat cacgatggcg agagtagaaa tattcatcag cctgaccgta
    33361 atatgaacca atagtagcag aaaaaccaag ttcttcaatc agttcacgct ctagggcctg
    33421 aagctgacct tcacctgctt caatttcacc accaggtaaa aaccaggaac cattaggagc
    33481 ttgaacaaga ataatttttg tttgttcgtg attgggaatg atagcataga caccgtaacg
    33541 tgtgacatag tctttatgtg catttttatg tccaaatgtt ggaatcatca ttttatttac
    33601 ctttcctttt tcttcattat actaaatttt tgctaattat tcttatcaat ttgtttagtt
    33661 taataaaaaa ttgatagaaa aagagagagt ctccttatag aaactctctt agctaacgtt
    33721 aatctagaga ctcttcgtta agaaaagaat ctccctcttt aacagcttta atcgtgatgt
    33781 tttcactgtt tgtcatcagt gcacgtaact gtttttcagt tgggtgttct aaataatagt
    33841 ctgtaatggc atcttcgata taatcttgga tagtacgacg gagcggccga gcgcccattt
    33901 taggatcata gcctaaatct actaattttt ctttgacctt ttgtgtcaca tcaagatgaa
    33961 tcccattata gcctaagcgc tcattaacat cttccagcat taaatcaacg atatgcagca
    34021 aatgttcttt agataaagct ttgaattcaa taataccatc gaaacgattc ataaactctg
    34081 ggctgaagaa gttgcttaat tcaccaagaa cagaacttgt ccgtccttct ctagcagcac
    34141 caaatccgac agaagcttcg cttttacctg ttccggcatt agaggtcatg ataataatgg
    34201 tgtccttgaa gctgactgtt cgcccttgac cgtctgttaa gcgaccgtca tcaagaactt
    34261 gtaagaacat gtgcatgacg tcaggatggg ctttttccac ctcatctaag agaataaggg
    34321 aataaggatt gcgacgaact tgttcggtta gctgtccagc ttcttcatag ccgacataac
    34381 ctggaggagc cccgactaat ttagcaacgg catgtttttc catgtattcg gacatatcaa
    34441 agcgaatcat attgtcagca gagccaaaga gttcaatagc tagttgctta gacaactctg
    34501 ttttaccaac acctgttggc ccaacgaata ggaaagaacc aataggacga tttggagttc
    34561 ccaatcccac acggttccgg cgaatggcct tggcaatttt gtcaacggca tcatcttggc
    34621 caatcacgtg agctttcaaa tcattagcca aattaacgag ttgagattgt tctttttctt
    34681 tcaagtcgcc aactggaata ttggtttttt gttcaatgat ggcttcaatg gttttttcag
    34741 taatgatagg aatatcttgc tcatcgactt tttgagcctg catttccttg tatttcgcaa
    34801 tttgatcgcg gaaataagct gcgcgttcat agtcttcgtc tcgagtagct tgcgccttga
    34861 gattctcagc ttcaataaga cgtttgtcaa tttctttagg atcaacaaag ttgagggtta
    34921 gattcatttt ggaaccagct tcgtccagaa ggtcaatagc cttatcagga agaaaacggt
    34981 cttgaatata gcggttagat aaatgagcgg cagcttcaat agcggctggg ctatatttga
    35041 catgatgata gtcttcgtat ttcggttgga taccttttaa aatcgtgatg gtttcctcaa
    35101 cagaaggttc atcaacttta acgggttgca tacgtcgctc caaggcagca tctttttcaa
    35161 taatacggta ttcatttaag gtagtagcac caacgagttg caactcacca cgggccaagg
    35221 ctggttttaa aatattacca gcatccatat tgccgtctcc tgcagaacca gcaccgacaa
    35281 tctcatgaat ttcatcaata aagagaatca catccttgcg attgcgaatt tcttccatta
    35341 atttttgcat gcgctcttca aactgaccac ggatacctgt tccctgaacg aggctaacca
    35401 catcaagacg aatcacttgc ttgccttgga gtttttgagg aacagtacca tcaataattt
    35461 tttgagccaa accttctaca acagcagttt taccaactcc aggctcacca attagcacag
    35521 gattattttt agtacggcgg ttgaggatct cgataacgcg tgtaatctct tcgtcacgac
    35581 caataacagg atcaatatta ccatttcttg caatatctgt gacattaatc ccaaactctt
    35641 ctaacaagcc ctttgcttgc tgatttggtg tttgtggctg agcaggtcgt tgtccgttgt
    35701 agttaccacc atagcgtcct ccgccatttc cattttgccc tgcctgagta ggtggggtat
    35761 ttggaagatt accaaaagct ctaaaattat tcaaatcacc aaaaaagtca tcaaagaaag
    35821 gacttgtgga tctatcttgt gctctatatc ctggggttag gccatttaaa atagaattgg
    35881 caggatcgga tttcatgatt tgataacaat tttgacagag atcaacctgt ctttgttttc
    35941 cattaacact tgtataaaga tgaatagtag attcgtttaa attacaattt tgacacagca
    36001 taatatacct ccgagggttt atctaaaagt caaagtcatt tagtcaaaaa tggtcaaact
    36061 ttatattcat attatagcac cacggcttgg gaaatcaagt aaaaagttta tcgctttagc
    36121 gttagctttt agagagtaac atgacagagt aactttatta ggtttccaat gagcaaatgt
    36181 ttaaaatcat tgaaaagagt aaaaaaagta aaatatcaat aaatatatta ctttccttgt
    36241 tagtttccct tgttttgtgt taaaataaga gggataaaaa acgaatagga gaaacgaaat
    36301 ggaatcacat ttggtgagaa tcatcaatcg tttggagttg atggtgacag atggcggtaa
    36361 tctcaagcga aattttgaac gcgatggtgt tgttgttgca gaagttgcct tttcaaatga
    36421 tcctgaaaat ggacctgttt tcacattgcg tgatgttgag gcgcgtgagt catattcctt
    36481 tgatagcatt gacttgattg caatggaaat ctacgattta ttatattaag cttgacatag
    36541 taaagagact tgcctgaggc aggttttttt attgtcaaaa agtattgtat taatattcat
    36601 cagatggtat aattatcttt attgtaatga acctaggact tatgaggaga tataaatgga
    36661 tttgtcattt ttgcccaaat actgggccta ctttaactac ggtgtacttg tcaccattat
    36721 gatttcagtc agcgttgtct tttttggaac ccttattggt gtcttggtaa ccctgattaa
    36781 gcgtagtcat gtgaagccgt tgacctgggt cgttaatctt tacgtttgga tctttcgggg
    36841 aacacctatg gtggttcaaa tcatgattgc ctttgcttgg atgcatttta acaatatgcc
    36901 tactattggt tttggggttt tagacttgga cttttcaaga ttacttcctg gaattattat
    36961 catttcattg aatagcggtg cttatatttc agaaattgtt agagcaggta ttgaggctgt
    37021 accaaaaggg caattagaag cagcttattc actaggtatt cgtcctcaaa atgccatgcg
    37081 ttatgtgatt ttgcctcagg cctttaaaaa tattttgcca gccttaggaa atgaatttat
    37141 taccattatt aaggatagtg ctcttttaca aaccattgga gtgatggaac tttggaatgg
    37201 tgcccaatcg gtggtaacgg ctacttattc tccaatttcc cctttactgg tggctgcttt
    37261 ttactactta atggtcacaa cagtgatggc acagttattg gcagtcttag aacgtcacat
    37321 ggcgcaagga ggtaatcatt gatgactgag gctattattt caattaaaga cttgcacaag
    37381 tattatgggc acaatgaagt gcttaaggga attgatttag acattatgcc aggagaggtt
    37441 gtggtgatta ttggcccttc tggttctgga aaatcgacct tacttcgaac tatgaatctt
    37501 ttggaagtac caactaaggg acagattagg tttgagggga ttgatattac cgataagaag
    37561 aatgatattt tcagcatgcg tgaaaaaatg ggaatggttt tccagcagtt taacctcttt
    37621 cccaatatga ctattttaga aaatatcact ttatcgccaa tcaaaactaa gggaatggct
    37681 aaagcagagg ctgacaaaac agccttgagc ttgttggaca aagttggatt atcagaaaaa
    37741 gccaaggctt atcctgctag tctttctggt gggcaacagc agcggattgc gattgcgcgt
    37801 ggactggcta tggatccaga tgttttactc tttgatgaac caacttcagc tctagaccca
    37861 gaaatggtgg gtgaggtctt ggctgtcatg caagatttgg ctaaatctgg gatgactatg
    37921 gttattgtga ctcatgaaat gggctttgct aaagaagtcg cagaccgtgt gatttttatg
    37981 gatggcggcg ttattgtgga agaaggaagt cctaaccaac tttttgatct gactaaagaa
    38041 gaacgtacaa aagatttttt gagtagagta ttataaatct gttctatgaa ttataaaagg
    38101 aagtcctaaa tgatttagga cttcctttta taatttgcta aggcatttta taggagatta
    38161 cttttctttt tgttaaaata aaaagaaata gttgcattat ttgcatagaa gaaagggatc
    38221 tgttatggtt tcagtgatgt ggtttcgtag agatttaagg attgatgatc aaaaagcttt
    38281 agctcatgct attgctagtc aatcaccaac cttatgtgtg tttcaattta acaaggagca
    38341 attaaatctg ctacatagtc ggaatcaatc tagttttatt actagcgttt tggcttttag
    38401 aaagttatta aaatgtgaag gtattgactt atatctaatg tatggagact taatgacctg
    38461 ttttgagcaa ttattgacac aattaaaaga ctggacagat gtgtatttta actatgatga
    38521 atctggatat ggtcgtttac gtgatcaaaa agcagcacaa tttttcaaaa aaaatgggat
    38581 tgccgttcat acctaccaag atcactattt acatggtagt caagagatca ttaaccaatc
    38641 aggtcagcct tataaagttt ttacgcccta ctataggatt tggcaaaatt atccgaaaga
    38701 gactcctatt aaagtagaac tatcgcaagg caggtggtta aatcttgaga caccagatga
    38761 tgttttaagg actgttgaga gctttaaaga tgaaaaatat caggatgttg caacttttga
    38821 tgaagcgtca aaacaactaa atcgatttat tcaagaccaa ttagcagctt atcacgctaa
    38881 tcgagatttt ccagcgcagc tagggacgag tcggttgtct ccttttttaa gaataggagc
    38941 tattggcatt cgcacggtat atcacgctgt gcgtcaagca ccaaatagtc tagggcaagc
    39001 tactttttta aaagaattag cttggagaga cttttacaat atggtctatg tggcttatcc
    39061 tgatcagaaa actcagccta tccaaaaagc cttttctcaa atcgaatggg ttaataatcc
    39121 tgactggttt cagttgtgga aagaaggtaa aacgggttac cctattgtcg atgctgcaat
    39181 gcttcagtta caaaagacag gatggatgca taatcgttta cgaatgatag tagcttcttt
    39241 tttaactaaa gatcttttat gtgattggcg tttaggagag cagcattttc aacaacaact
    39301 aattgattat gatgctgcca gtaatatcgg aggatggcag tgggctgctt ccactggaac
    39361 agatgctgtt ccttatttta gagtatttaa tcctgttact caaagtaagc gctttgatcc
    39421 caaaggcgag tttattaaag cgtatttgcc tcaactagaa cacgttccag agaagtatct
    39481 ccacgaaccg tggaagatgc caaaatacct tcaagagagt gtgtcctgta ttattggcac
    39541 agactatcct caaccaattg tcgatcatgc taaacaacgt gaacaagcta ttgcaaagta
    39601 tgagtgggca aaagaaaaag caaaaataga atgactgttc tcattataag agtttaaaca
    39661 aaaagttatc atgaattaag attatttaat ttaaaaaaca agttgacttt atttagatta
    39721 tttgatacta ttcagttgtc tcccttagag aaagcgattt cttgttttgg agctgatttt
    39781 taccatttgg tcttagaata ggatgagtaa tatgacttac aacgaggtat atcaagaatg
    39841 gttgcacaat aatgatctta gtgatgatat taaagcagat ttagcagcca taaaagacaa
    39901 tgaggctgag attcaagatc gtttttacaa aacacttgaa tttggaacag cagggctaag
    39961 aggaaaactt ggagcaggca ccaatcgcat gaatacctat atggttggta aggcagcaca
    40021 agctttagct aatactatta ttgatcatgg acctgaagca gttaaaaagg gcattgcggt
    40081 tagttatgat gttcgctatc aatctagaac atttgcagaa ttaacatgct ctattatggc
    40141 agctaacggt attaaggcgt acctttataa agggattcgg ccaacaccaa tgtgttcgta
    40201 cgctattcgt gctttgggat gtatctctgg tgttatgatt acggctagtc acaatcccca
    40261 agcttacaat ggttataaag cttattggca agaaggttct caaattttgg atgacattgc
    40321 ggatcaaatt gcacaacaca tggctgcact aactcagtat caggaaatca aacaaatgcc
    40381 ttttgaaaag gctctggaca gtggacttgt tacttatatt gatgagagta ttgaagaagc
    40441 atataaaaaa gaagtgcttg gtttaacgat taatgatact gacattgata agtcagtccg
    40501 agtagtctat actcctttaa atggtgttgg gaatctacca gtgcgtgagg ttttaagacg
    40561 ccgcggtttt gaaaatgttt atgtggtacc tgagcaggaa atgcccgatc ctgattttac
    40621 aacagttggc tatcctaatc ccgaagtccc taaaactttt gcatattcag aaaaattagg
    40681 taaggcagtt gatgctgata ttttgattgc aactgatcca gattgtgacc gtgtggcttt
    40741 agaagttaaa aacgcagtcg gtgactatgt ttttctcaat ggcaataaaa tcggagcgct
    40801 tttatcttac tatatctttt cacaacgatt tgacttaggc aatttaccgg ctaatcctgt
    40861 tttagtgaaa tccattgtaa caggagactt gtcacgggct attgctagcc attatggtat
    40921 tgaaaccgtt gaaacattga ctggttttaa gaatatttgt ggcaaggcaa acgaatatga
    40981 tgtgacgaaa cagaaaaact atctgtttgg ttatgaagaa agtattggtt tttgctatgg
    41041 cacttttgtt cgtgacaaag acgctgttag cgcctctatg atgattgtag aaatggcagc
    41101 ttactacaag aaaaaggggc agaatttact agatgttttg cagactattt atgcgacatt
    41161 tgggtattat aatgaacgtc aaattgcctt ggagcttgag gggatagaag gacaaaaacg
    41221 cattgcgagg ataatggaag atttcagaca gacaccaata gctagtgttg cagagatggc
    41281 gttagacaag acaattgatt ttattgatgg ctatcaagat tttccaaagc aaaactgtct
    41341 caaattttat ttggatgatg gttcttggta tgcacttaga ccatcaggaa cagagcctaa
    41401 aataaaattt tatttatata ctattggcca aacacaagaa aatagtgcaa caaaattaga
    41461 tgctattgaa gcagcgtgtc gcacaaaaat aaatcaggtt aattaaacat caaaaatgga
    41521 taacactttt acactatttt tccatataaa caactacaaa aggaggtgag acttttaggc
    41581 accttctttt tcttgtaggt gtcactaatc aatttaatcg actcaaacca atactaaaaa
    41641 ataagtaaga gtataaagaa caggcatcta tttttttgtt ataatagaaa aatgaaatta
    41701 aagggagatg tcaatgacag aactaattga tggtaaagcc ttagctcaaa agatgcaaca
    41761 agagttagca gctaaagtca acaatctaaa acaaaaaaaa ggaattgtac caggcttagc
    41821 cgttattctt gtaggtgatg atcctgctag tcaggtgtat gtccgtaata aagagcgtgc
    41881 agctcttact gtaggtttta aaagtgagac cgttagatta tcagaattca tttgtcaaga
    41941 agagcttatt gcagtaatcg aacgttacaa tgcagataac actattcatg gtattttagt
    42001 gcagctaccc ctgccaaatc atattaatga taaaaaaatt attctcgcca ttgatcccaa
    42061 aaaagatgtg gatggttttc acccgatgaa tacaggtcac ctttggtcag gacgtccctt
    42121 gatggttcct tgtactccat cagggattat ggaattgctt cgagaatata atgttaacct
    42181 tgaaggtaaa catgccgtca ttattggcag atcgaatatc gttggaaaac caatggcaca
    42241 gctcttactg gacaaaaatg caacagtcac gttgacacat tcaagaacac gtcaattaga
    42301 agaagtatgt cgctgtgcag atgtgttgat tgtggcaatc ggacaaggtc atttcataac
    42361 aaaacaatat ataaaagagg gtgcgatagt gattgatgtg ggaatgaacc gtgatgataa
    42421 tggcaagcta attggagatg tggcctttga tgaggtggca gaagttgcag cgaaaatcac
    42481 ccctgtacca ggaggtgtcg gtcctatgac gattgctatg ttgctagagc aaacttatca
    42541 atctgctctc cgtagtactc ataaatagtt atcattagac aattcaacat aagagaatat
    42601 aagaagtcag caatggcttc cttttttgtt tttctgctca ctatttatcc agaaaaatgg
    42661 tataattgca ttagtatgca aagggactat gtcaggtcca actaagtgaa aggtggcttg
    42721 atggcagatt atttaaccgt cactcatttg acgaaatatt taaaattaaa atttgaccgt
    42781 gacccttatt tggaacgggt ttatctgact ggtcaagtgt ccaattttcg aaaacgacca
    42841 actcatcaat atttttcctt aaaggatgaa agtgctgtga ttcaagccac catgtgggca
    42901 ggagtctata aaaaactagg attcgaccta gaagaaggca tgaaaattaa tgtaattggg
    42961 cgagttcaac tttatgaacc tagtggctct tactctatcg tgattgaaaa ggcagagcca
    43021 gatggtatag gtgccttggc tttgcagttt gaacaattaa agaaaaaatt aacggcagaa
    43081 ggttattttg agcaaaaaca caagcagcct ttgccacagt ttgtatcaaa aattggggtc
    43141 attacaagtc ctagtggtgc tgtgattcga gatattatca caaccgtttc acggcgtttt
    43201 ccaggggttg agattttatt attcccaact aaagtacaag gtgatggagc cgcccaagaa
    43261 gtagtggcta atattcgaag agccaatcaa agagaggatt tggacttgct cattgtcggc
    43321 cgtggaggtg gctcgataga agacctttgg gccttcaacg aggaaatagt ggttcaggct
    43381 atctttgaat cgcaacttcc agtgatttcg agtgtgggtc atgaaacaga cacgacttta
    43441 gcggattttg tggcagatcg cagagcagcc acaccaacag cagcagcaga gttagcaacg
    43501 cctattacaa aaacagatct tatgtcttgg atagtagagc ggcaaaatcg ttcctatcag
    43561 gcctgcttga ggcggattaa gcaacggcaa gagtgggtgg ataaactctc gcaatctgtt
    43621 atttttaggc aaccagaacg attatatgat gcctacctgc aaaaaattga tcgccttagc
    43681 atgaccctga tgaatacgat gaaagatcgt ctgagttccg ccaaagaaaa caaggttcag
    43741 ttggaccatg ccttggccaa tagtcaatta cagacaaaaa tcgagcgata ccaagaccgt
    43801 gttgctaccg ctaagcgttt actgatggct aatatggcta gtcaatatga tagtcagctg
    43861 gctcgctttg aaaaagcaca ggatgctttg ctatcactgg ataccagccg aattatcgcc
    43921 cgtggttatg caatgattga aaaaaatcaa gcactggtag cctctgtaag tcagataaca
    43981 aagggtgatc agttaaccat taagatgcgt gatggacaat tagatgtaga ggtaaaagat
    44041 gtcaaaaacg aaaacatttg aagaaaattt acaagattta gagactattg tgaacaaact
    44101 tgaaaatggg gatgtccctt tggaagaagc tatttcagaa tttcaaaaag gaatgcttct
    44161 ctcaaaagaa cttcaaaaga ccttacaagc ggcagaaaaa acactcgtca aagtgatgca
    44221 agctgatggc acagaagtag atatggatga ttaatggaca aattagctag aattgacgaa
    44281 gccattcgtc gctactataa gacgactagt aacggtgtat ctgaagagtt gattgatgct
    44341 atcttgtatt ctgttgacag tggtggcaag cgcattcgac cacttatctt attagagatg
    44401 attgagggat ttggggtatc gttacagaat gctcattttg atttggctgc agcccttgaa
    44461 atgattcata caggaagtct gattcacgat gatttgccag ccatggataa tgatgattac
    44521 cgacgtggta gactgaccaa tcacaaacaa tttggagaag ccacggccat tttggcggga
    44581 gatagcttat ttttagaccc ctttgggtta atagctcaag ctgaattaaa tagcgaggtt
    44641 aaagtagcct taatccaaga actttcccta gcttcaggaa cttttggcat ggttggtggt
    44701 cagatgctag atatgaaagg ggaaaatcaa gctttgagtc tccctcagtt gtcactgatt
    44761 cacctcaata aaaccggaaa attattaact tttcctttta aagcagcagc tcttgtaaca
    44821 gaacaggcta ttactgttcg tcaacaacta gagcaggcgg gaatgctcat cgggcacgcc
    44881 tttcagatta gggatgatat tttagacgtg acagctagct ttgaagatct tggaaaaacg
    44941 cctaaaaagg atttatttgc agaaaaagct acttacccaa gtttattggg gttagaagcc
    45001 tcctgccaac tgttgacaga gagtttagat caggctttga cgatttttca gacactcgaa
    45061 agcgatgtag gctttaagcc tcaaataatt acaaaactga tagaagggtt acgacttaat
    45121 gcctaaagaa agagtagatg tgttagccta taagcaagga ttatttgaga ccagagagca
    45181 agctaagcgt ggtgttatgg ctggcttagt ggtctctgtg attaatggcc aacgctatga
    45241 caagccaggt gacaaaattg acgatgggac tgagttaaaa cttaaaggtg aaaaactcaa
    45301 atacgtcagt cgtggtggat taaaactgga aaaggggctg cacgtttttg gtgtatcagt
    45361 tgctaatcaa attgggattg atattggcgc ttcaacaggt ggctttaccg atgttatgtt
    45421 acaagatggg gccaaactag tctatgccgt cgacgttggg actaaccagt tggtatggaa
    45481 actcagacaa gatccacgag taagaagtat ggaacagtat aactttcgtt atgctcagcc
    45541 agaggacttt aatgagggac agcctgtatt tgccagtatt gatgtgtcct ttatttctct
    45601 cagcttgatt ttgccagccc tgcataacgt tttgtcagat cagggacagg ttattgctct
    45661 cattaaaccg caatttgaag ctgggcgcga gcagattggt aaaaaaggca tcgtcaaaga
    45721 caaacagatt catgaaaaag tgattcaaaa ggtcatggat tttgcctcag gttacggatt
    45781 tacagttaag gaacttgatt tttcccctat tcagggtggt catggaaata tcgaattttt
    45841 agctcatctt gttaagtcac agacacctga aacgttagcc ccacatctga ttcaggaagt
    45901 tgttgccaag gcacataagg agtttgagaa acatgaaaaa aagtgaacga cttgaattaa
    45961 tcaaaaaaat ggttttgacg catccaattg agacgcaaca tgacctctta agattattgg
    46021 cagagcatgg gttagaatta acccaggcta ctatttcaag agacatgaat gaaattggta
    46081 tagtaaagat tccttctggc agtggacgtt acatctatgg tctttctcaa gatagtggaa
    46141 aaaagatcgt tcaaggacct agatcgataa agagcactat tttagctgta tctgacaaaa
    46201 caaaaggttt agaacaacac ctctatttaa aagtcgtacc tggcaatagt aaattaatca
    46261 aacgttattt attagcagat ttttcaaaag ctatttttag tcttattgct gatgatgata
    46321 gtttattgtt aattgcaaag tctccttcag aagcagatat gatacgccaa gaaattttgc
    46381 tttggatgca gggtataacc tagaaaaaat aggggagaaa gtgatgttat tagaaatttc
    46441 cattaaaaat tttgctatta ttgatgaaat ttccctaaat tttgaaaatg gtatgacggt
    46501 tttgacgggt gaaactggag caggaaagtc tattatcatt gatgctatga atatgatgct
    46561 tggtgcgcgt gctagtacag aagtgattcg tcgtggagct aataaagcag aaattgaggg
    46621 gttcttttcg gtagatgcta ccccagaact ggttgcgtgt ctggaatcat caggtattgc
    46681 tatggaagaa gaactgatta ttcgccggga tatctttgcc aatggcagaa gcgtgagccg
    46741 cattaatggt cagatggtta acctagccac cttaaaacag gtcggacagt ttttggtaga
    46801 tattcatggg caacatgacc aagaagaatt aatgcgacca cagctccacc agcaaatttt
    46861 ggacgctttt ggtgataagg cttttgagca attgaaagag aactatcagc ttatttttga
    46921 tcgttataaa agcttgcgtc gccaggttat tgacaaacaa aaaaatgaaa aagaacataa
    46981 agatcgtatc gacatgttgg cttttcagat agcggagatt gaagctgctg ccttgagtcg
    47041 aggtgaggac gaccggttaa atcaagaacg tgatcgctta atgaaccaca aacaaattgc
    47101 tgataccctg accaatgcct acgtcatgct agataatgac gatttttcaa gtctatccaa
    47161 tattcgctct agcatgaatg acttactatc aattgagcag tttgattcag agtacaaagg
    47221 gatgtcgact tcgatttctg aagcctatta tattcttgaa gaagtgagca agcaattatc
    47281 agataccatt gaccaactgg attttgatgg tgggcgatta caggaaattg aatttcgctt
    47341 ggatacactc aatagcttaa cccgtaaata cggtggtaat gtgaatgatg tgcttgacta
    47401 ctacgataat attatcaaag aataccagct attaacagga gatgacttgt cttcagggga
    47461 tctagaggca gaattgaaaa gcttggaaaa acaattggtt gctgctgctt cggagttaag
    47521 tgtctctcgc catcaattgg cggagcaatt agaagctgag attaaagctg aacttaagga
    47581 actttatatg gaaaaagcag atttcaaagt tcactttacc acatcaaaat tcaatcgtga
    47641 tggtaatgaa agcttggaat tttacatctc tactaatcca ggcgaaggat tcaagcccct
    47701 tgtcaaggtg gcttctggag gagagttatc acgccttatg ttagccatca aggctgctat
    47761 ttctagaaaa gaagataaga cgagtattgt ttttgatgaa gtagatacag gtgtttctgg
    47821 tcgcgttgcg caagctattg cccaaaaaat ttataaaatt gggcgacatg ggcaagttct
    47881 cgctatttca cacttacctc aagttattgc tattgctgat tatcagtatt ttatttctaa
    47941 agaaagtaaa gaagagtcca ccgtttctaa ggtaaggtta ttaactcctg aagaacgtgt
    48001 ggaagaaatt gctagcatga ttgcaggaac agatatgaca caagctgctc ttacgcaggc
    48061 tcgtgaacta cttgccaaac attaagatta tgtttggtat ttgatatttt cataattaga
    48121 tgacattgat tttttaggtg ctaaaataat cattgtgtca gaccattttt cctctgttaa
    48181 tctggcttgg tttgccttga caaacctctg agaaatagta gaatagataa gagaatttta
    48241 agctgagggg atagaaatga ctagtaaaaa agcgtgttta tcaagcatca ttgtgttagc
    48301 aagtttaacg tgtggaaatg atactgttag tgccaatcat ctctcagcaa ctggagataa
    48361 gtttgatgat tgctcaacac ttgttgaaaa agatgtggcc cctaaagatg aacttgagat
    48421 gttagcatgg tcctcgtctc aaacaactga tgatgctgac agagactatg aagattttct
    48481 cgatgatgat tcttttaatg atgattcttt tatttctcaa aatgaaactg ataagatgtt
    48541 tgagaattta actgatgata ggttattaga tgaattagat gaagaagata caattgagcc
    48601 agagcaaaat gtaataatgc ctagtgacga tgagctattt gatttaactg atgctgttga
    48661 gacacgcctt actgtttcta gtgctcccca tttagaggct gaattgccga aaccacattt
    48721 gaggagccta tcagatacag cactgcggtc tggtgaaatt agaggacatt tagataacaa
    48781 actggacgct ttgtctgtaa cagctacaaa gttagcatta acgatggctc aaaaatttga
    48841 tttgacaacg catgtctatt ctataggtga aagctttagt gaagtattag ctgctcatta
    48901 tgaagacaga aaagcagaat cagctttttc taagaaaaag agatttcacc ttcctattgc
    48961 tactccagat gttgttatag aggagttaag gcgcctggtc tcttctattg gaagttcaaa
    49021 agaagatgtt tcagttcctt ataatcggaa gctaggtatg gcagttgcaa aaagaaaaat
    49081 agccctgcca caaacgggag aggagttctc ttattatcca gctttacttg gtttaatgat
    49141 attaggatta acgccgatta tgataccaaa gaagataaat aattaggtaa taagttattg
    49201 tagttgtaaa agacggggca aatgttcaag cgtgaaaagg ttgacttttg cctcgttttg
    49261 tatctcgtta ttgctaaggc attttcttcg agcagctagt gctcgccata cctatctacc
    49321 gagtgactat tcaatagcac taccagtttt gctttattta gcaaggagtg ttagaataaa
    49381 gaggtgagaa actagtttag aatggaaaaa tacatgggaa ctataaaaat tgttacagat
    49441 tcatcaataa ctattgaacc agaattaatt aaagctttag atattactgt agtgccttta
    49501 tctgtcatga ttgatagcaa attatattct gataatgatt taaaagaaga aggtcatttt
    49561 ttgagtctta tgaaggctag caaatccctt cccaaaacca gtcagccacc ggttggtctc
    49621 tttgctgaaa cttacgaaaa tttggtcaaa aaaggagtaa ctgacattgt tgctattcac
    49681 ctctcaccag ctttatcagg tactattgaa gcttcccgtc agggggctga aatcgctgag
    49741 gcacctgtta cagttttaga ttcaggattt actgatcaag ccatgaaatt tcaggtcgtt
    49801 gaggcagcaa agatggcaaa agcgggtgct agtttgaatg agattttggc tgctgttcaa
    49861 gctatcaaat caaaaacaga gctctacatt ggtgtatcta ccttagaaaa tttagtaaaa
    49921 ggaggtcgta ttggtcgtgt gacgggtgtt ttgagctcgc tacttaatgt caaagttgtt
    49981 atggcactta aaaatgatga gttaaaaacg cttgtcaaag gtcgaggtaa taaaacattt
    50041 acgaaatggt tagatagtta cctcgctaaa aatagtcatc gcccgattgc agagatagct
    50101 atttcttatg ctggtgaagc tagcctggca ttaaccttaa aagaaagaat cgcagcttat
    50161 tacaaccact ctatttcggt tttagaaaca ggctctatca tccaaacaca tacaggagaa
    50221 ggagcttttg cggttatggt tcgttatgaa taatcgtcat ttatttagtg ggatattttt
    50281 ctttgttatt agtttatgtc tggccttttt attgctaaat attattatcc ctaagtcaaa
    50341 ttcacgtttg aaaaagagtg attttctgac aaaagaacaa gtagctatcc aatatgttgc
    50401 tataggagat tcattgacag aaggagtagg tgatctaact catcaaggtg gttttgttcc
    50461 tttgttaacg aatgatctca gtgaatattt taaggctaat gttaatcatc aaaattacgg
    50521 cgtatctggt gataccagtc aacagattct tgataggatg ataaaacaaa agcagataca
    50581 gttatcttta aaaaaagcag atataatgac gttaaccgtt ggtggtaatg atgttatggc
    50641 agttattcgg aagaatttag cggatttgca agtttctagt tttagaaagc cagctcgtca
    50701 gtatcaaaaa cgattaagac agattatcga gttagccaga aaagataata aagatcttcc
    50761 tatttttatt ttaggcatct ataatccgtt ttatttgaat tttccagaac taactgatat
    50821 gcaaaaagtg attgatgact ggaatatcaa aactaaggag gttgttggag aatacgatcg
    50881 tgtgtacttt gtgccaataa atgacctctt gtataaaggg ataaatggac aagaaggaat
    50941 tgtccattct tcaggagatc aaactacaat tgtcaatgat gccttgttta ctggggacca
    51001 ttttcaccca aataatactg gctatcaaat catgtcaaat gcagtaatgg agaaaattaa
    51061 aaagcatgaa aaaaaaatca aaccttaatt ggtggaagtg gagcttctta tgtctgcttg
    51121 cttttaatac cgcctttttg atggttattg caagtcgtct cattcaagta agagaacctg
    51181 agtcagaact gattgctaaa aaaccagtta aaaatatcaa aattggtaca tttgtcacaa
    51241 ccagagaaca gcttaacgaa actgtagcaa gttatcttaa agattatcag actaaaaaaa
    51301 tgtcttataa attttatgcg acatcttctt ctattttgtt tgaaggaact tatcaattat
    51361 tagggtatga agtcccttta tatatctatt ttcaacctca tcgtctagaa aatggagctg
    51421 tccaactaca ggtgatctct ttttcagtgg gaactctgcc actcccagaa aaagatgttt
    51481 tgcagtattt gaaatcaagc tacaaattgc caagctttgt taaagtgatg ccaaatcaat
    51541 cagctatcgt tgttaattta caagatatcc aaaatgatgc taaggtttat ttaaaggcca
    51601 agaaaattga tttatttaat gatgaaatca gttttaacat ctataagaaa taagctcaaa
    51661 taacgttaaa tacttgacct aatcgctttt tttagatatg ataatatctg ttaaagcatt
    51721 aagcttacta attatttgga ggatttgtta aatggctaac aaacaagatt taatcgcaaa
    51781 ggttgcagaa gcaactgaat tgactaaaaa agattcagca gcagcagttg atgccgtgtt
    51841 ttctacaatc gaagctttcc ttgctgaagg tgaaaaagta caattgatcg gttttggtaa
    51901 cttcgaagta cgcgaacgtg cagctcgtaa aggtcgtaac ccacaaactg gtgcagaaat
    51961 tgaaattgca gcttcaaaag ttccagcctt caaagctggt aaagctctta aagacgctgt
    52021 taaataattc gtctagaaaa atcttgttgc tatcgatgtt tattgatagc gacaaggttc
    52081 tttttttata tttggggcat aaagttagta gttttctctt cagttaagct aagttctaat
    52141 gcatgcactc tataatggtc agtcatcctt ctattagtat atcatttccg caggtagggg
    52201 gagttttttt catatttgca aatagttgaa gttaggattt ttgaaagcaa aaggtaagtt
    52261 taaaaaaagt ttatttagaa tgtttctaaa ttacttgact tatttattta
//
LOCUS       DAUGUF010000010        51280 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUGUF010000010 DAUGUF010000000
VERSION     DAUGUF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51280
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.010"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..220)
                     /locus_tag="VIB71_000575"
     CDS             complement(<1..220)
                     /locus_tag="VIB71_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8822329.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAI"
     gene            complement(210..1337)
                     /locus_tag="VIB71_000576"
     CDS             complement(210..1337)
                     /locus_tag="VIB71_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8822330.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            complement(1334..2314)
                     /locus_tag="VIB71_000577"
     CDS             complement(1334..2314)
                     /locus_tag="VIB71_000577"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8822331.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            complement(2454..3032)
                     /locus_tag="VIB71_000578"
     CDS             complement(2454..3032)
                     /locus_tag="VIB71_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEQ8822332.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFANSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHIAFKYAKSKVARCINTLKKFNDK"
     gene            3120..3791
                     /locus_tag="VIB71_000579"
     CDS             3120..3791
                     /locus_tag="VIB71_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8822333.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            3766..4602
                     /locus_tag="VIB71_000580"
     CDS             3766..4602
                     /locus_tag="VIB71_000580"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEQ8822334.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGET
                     DS"
     gene            4599..5504
                     /locus_tag="VIB71_000581"
     CDS             4599..5504
                     /locus_tag="VIB71_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8822335.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            5508..6503
                     /gene="pta"
                     /locus_tag="VIB71_000582"
     CDS             5508..6503
                     /gene="pta"
                     /locus_tag="VIB71_000582"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEQ8822336.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            6629..7384
                     /locus_tag="VIB71_000583"
     CDS             6629..7384
                     /locus_tag="VIB71_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEQ8822337.1"
                     /translation="MGNIALVTGASAGFGRAIVEHLIADGIKVIGAARRLEKLKALET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDAGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(7578..8267)
                     /locus_tag="VIB71_000584"
     CDS             complement(7578..8267)
                     /locus_tag="VIB71_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEQ8822338.1"
                     /translation="MKNAISILALLTPENQLEDTFIRELSHHFSHLFEVTILTSKANI
                     QSNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATTVLLLSQYLTRF
                     YQKFDGYFLQYLPLQARLSDAKGNILVDNHAFNGSFLPTTDNEIEDWILAELRLSDSP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            8693..9421
                     /locus_tag="VIB71_000585"
     CDS             8693..9421
                     /locus_tag="VIB71_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822339.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVVNLFGGDEHA"
     gene            9414..10940
                     /locus_tag="VIB71_000586"
     CDS             9414..10940
                     /locus_tag="VIB71_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEQ8822340.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDMYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            11218..12201
                     /gene="guaC"
                     /locus_tag="VIB71_000587"
     CDS             11218..12201
                     /gene="guaC"
                     /locus_tag="VIB71_000587"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEQ8822341.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAYEY
                     EFVTSLKEDTPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVNGETFKEYYGSASAYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      12324..12419
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12506..13087
                     /locus_tag="VIB71_000588"
     CDS             12506..13087
                     /locus_tag="VIB71_000588"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEQ8822342.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            13087..14370
                     /locus_tag="VIB71_000589"
     CDS             13087..14370
                     /locus_tag="VIB71_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEQ8822343.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSSAM
                     FGALIASGIYVSLVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVIIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(14434..15372)
                     /locus_tag="VIB71_000590"
     CDS             complement(14434..15372)
                     /locus_tag="VIB71_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEQ8822344.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQVAGVKPVSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTSKGKQYHHILDRQTGCPIETDMLSLTIMAPSSFYCDIWATRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(15425..15610)
                     /locus_tag="VIB71_000591"
     CDS             complement(15425..15610)
                     /locus_tag="VIB71_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEQ8822345.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            15748..16317
                     /locus_tag="VIB71_000592"
     CDS             15748..16317
                     /locus_tag="VIB71_000592"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEQ8822346.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            16352..17431
                     /gene="prfA"
                     /locus_tag="VIB71_000593"
     CDS             16352..17431
                     /gene="prfA"
                     /locus_tag="VIB71_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEQ8822347.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DQKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            17431..18270
                     /gene="prmC"
                     /locus_tag="VIB71_000594"
     CDS             17431..18270
                     /gene="prmC"
                     /locus_tag="VIB71_000594"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEQ8822348.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            18254..18844
                     /locus_tag="VIB71_000595"
     CDS             18254..18844
                     /locus_tag="VIB71_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEQ8822349.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILVFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITTALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            18862..19314
                     /locus_tag="VIB71_000596"
     CDS             18862..19314
                     /locus_tag="VIB71_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8822350.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            19304..20560
                     /locus_tag="VIB71_000597"
     CDS             19304..20560
                     /locus_tag="VIB71_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEQ8822351.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     HYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            20567..21544
                     /locus_tag="VIB71_000598"
     CDS             20567..21544
                     /locus_tag="VIB71_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEQ8822352.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            21545..22144
                     /locus_tag="VIB71_000599"
     CDS             21545..22144
                     /locus_tag="VIB71_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEQ8822353.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            22154..23872
                     /locus_tag="VIB71_000600"
     CDS             22154..23872
                     /locus_tag="VIB71_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822354.1"
                     /translation="MKRLRPYLKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLVSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEVPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPINDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGE"
     gene            23875..25602
                     /locus_tag="VIB71_000601"
     CDS             23875..25602
                     /locus_tag="VIB71_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822355.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQLVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRGEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            25843..27213
                     /locus_tag="VIB71_000602"
     CDS             25843..27213
                     /locus_tag="VIB71_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEQ8822356.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(27372..28355)
                     /locus_tag="VIB71_000603"
     CDS             complement(27372..28355)
                     /locus_tag="VIB71_000603"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEQ8822357.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            28546..31032
                     /gene="gyrA"
                     /locus_tag="VIB71_000604"
     CDS             28546..31032
                     /gene="gyrA"
                     /locus_tag="VIB71_000604"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEQ8822358.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDTLAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIDEINTDRENSISKNKDN"
     gene            31052..31801
                     /locus_tag="VIB71_000605"
     CDS             31052..31801
                     /locus_tag="VIB71_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEQ8822359.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIVVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLEK
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            31884..32297
                     /locus_tag="VIB71_000606"
     CDS             31884..32297
                     /locus_tag="VIB71_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8822360.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            32911..33351
                     /locus_tag="VIB71_000607"
     CDS             32911..33351
                     /locus_tag="VIB71_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822361.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEEKWQDTKDAVEVYGGIAAE
                     TVEESLGQAKEKVEGIGEATSQTIQSKMEKLTSDKTDADDDDEK"
     gene            complement(33401..34312)
                     /locus_tag="VIB71_000608"
     CDS             complement(33401..34312)
                     /locus_tag="VIB71_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8822362.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(34429..35079)
                     /locus_tag="VIB71_000609"
     CDS             complement(34429..35079)
                     /locus_tag="VIB71_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEQ8822363.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(35076..35516)
                     /locus_tag="VIB71_000610"
     CDS             complement(35076..35516)
                     /locus_tag="VIB71_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEQ8822364.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLLQEVTQ"
     gene            35735..36583
                     /gene="ylqF"
                     /locus_tag="VIB71_000611"
     CDS             35735..36583
                     /gene="ylqF"
                     /locus_tag="VIB71_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEQ8822365.1"
                     /translation="MATIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTHY
                     PSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDVD"
     gene            36573..37364
                     /locus_tag="VIB71_000612"
     CDS             36573..37364
                     /locus_tag="VIB71_000612"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEQ8822366.1"
                     /translation="MSTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKA
                     IQAELAEEERLEAMLSYEKALYKKGYQAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     SQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            37429..38265
                     /gene="dprA"
                     /locus_tag="VIB71_000613"
     CDS             37429..38265
                     /gene="dprA"
                     /locus_tag="VIB71_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEQ8822367.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            38372..40501
                     /gene="topA"
                     /locus_tag="VIB71_000614"
     CDS             38372..40501
                     /gene="topA"
                     /locus_tag="VIB71_000614"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEQ8822368.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSIAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSINFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMEEGENVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(40576..41460)
                     /locus_tag="VIB71_000615"
                     /pseudo
     CDS             complement(40576..41460)
                     /locus_tag="VIB71_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            41473..42039
                     /locus_tag="VIB71_000616"
                     /pseudo
     CDS             41473..42039
                     /locus_tag="VIB71_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
     gene            42054..43046
                     /locus_tag="VIB71_000617"
     CDS             42054..43046
                     /locus_tag="VIB71_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEQ8822369.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESSLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWRLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNA
                     DLFKSFKKGAILMNMARGALIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            43151..43816
                     /locus_tag="VIB71_000618"
     CDS             43151..43816
                     /locus_tag="VIB71_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEQ8822370.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            43809..44525
                     /locus_tag="VIB71_000619"
     CDS             43809..44525
                     /locus_tag="VIB71_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEQ8822371.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILVITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGLCMIMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            44688..46034
                     /gene="trmFO"
                     /locus_tag="VIB71_000620"
     CDS             44688..46034
                     /gene="trmFO"
                     /locus_tag="VIB71_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEQ8822372.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIDVIRDEITEIPDDAITVIATGPLTSDALAEKIHAVNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRNNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALVFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            46211..47608
                     /locus_tag="VIB71_000621"
     CDS             46211..47608
                     /locus_tag="VIB71_000621"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEQ8822373.1"
                     /translation="MQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTILDKIGYYSL
                     ECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHYADDIVDKF
                     ISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVHTLNYYLSL
                     VKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSGISEMTYLK
                     VAEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRD
                     HYRETGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLAEQGLADKYEEVLAEVPKVRAD
                     LGYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKI
                     IGDEAVIACRPADLIEPQMIYLRDEIAPYARSEEDVLSYASFPQQTRDFLGRREDPFY
                     DVPVQEVTVQLDIQD"
     gene            complement(47719..48771)
                     /gene="citC"
                     /locus_tag="VIB71_000622"
     CDS             complement(47719..48771)
                     /gene="citC"
                     /locus_tag="VIB71_000622"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEQ8822374.1"
                     /translation="MPYYTVSKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDQSLVPFSVRKMLIQEGLRHLDNIIFHETGPYLISQ
                     ATFPAYFQTEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(48860..49342)
                     /locus_tag="VIB71_000623"
     CDS             complement(48860..49342)
                     /locus_tag="VIB71_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEQ8822375.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            complement(50036..51106)
                     /gene="xerS"
                     /locus_tag="VIB71_000624"
     CDS             complement(50036..51106)
                     /gene="xerS"
                     /locus_tag="VIB71_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEQ8822376.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT        16051 a         9042 c        10385 g        15802 t
ORIGIN      
        1 tgatagctaa tttaaaacct gtgagttctt tattaatagt gatttttaaa gggaaaccat
       61 cccctgaatt aggtattttt tcgagtaaac gtattaattg gtagtgccct actttagttt
      121 gactaaatgt agtatctctt agggtatatt ttttaatgtt tggactgatt gtataaaggt
      181 atttacagtc tttaagctta atttcttttt caaaagccat ctgttcctcc taaaatattt
      241 tttaatgttt gagctaattg attaacatct tcaatgctat tttgatctga aaaactgata
      301 cgaattgatt cttttaaacg agaagagtca tccccatagt acgcagctaa aacatgactt
      361 ggattaacag ctccagcagt acaagcagaa ccagttgata ctgcaatgcc tgctaagtca
      421 agttgtgtta gtaaaatagt attttggtag cctaaaaatc caatattgag aacatgagga
      481 agataatgag taccttgatt aatatagtag ggtagtcctt ctaggaggct aatcaagtga
      541 tgacgtaaac tgataatgtg atcagttgat tggtcaagac aagtcatagc atcagtcaaa
      601 gcttgtgcca taccaataat acctaacata ttttcagtac ttgcgcgtcg ctttccttct
      661 tgatcacccc cgtgaagaag agggtcgatt ggttgtccgt tactgtataa aaagccgcat
      721 cctttaggac catgaaattt gtgagcagaa gcagataaaa agtcaatccc aagttcgcta
      781 ggaataatct tgagtttgcc aacagcttga acggcatcaa catgaaaagc agcttgatgg
      841 tctttgagca gattcccaat gtccttaata ggtaacaggt cacctgtttc gttattggca
      901 tacattatgc ttaccaaaat ggtgtcatct ctcaaggctt gttttaagtc agataaattt
      961 atttgtccat tttgacaagg caaataagtg acctcaaaac caaatcgctc ttcgagatag
     1021 gccatggtat gaagcacaga gtggtgctca atagtagttg tgatgagatg tttgcccttt
     1081 gcttgatgag ctaaagcata gccttttatg gccatattat tgctttcagt tccaccggac
     1141 gttactataa tttgctgttc acttgccccc aagtttctag cgatagcttg tcggcattca
     1201 cgaaggattt tattggctcg gcgcccgtag aaatgaatac tagaggggtt accaaagtta
     1261 tcttgcatag ctgctgtcat cgccctaatc acattaggac taagtggtgt ggtggcggcg
     1321 ttatcaaagt aagtcatgcg ttatttttgc ctttaggttg ataagaaaaa agtggactta
     1381 agggtcttct ttcatggatg cgaataatag cttctgcgat taaatcactg gcgctaagat
     1441 aagtaacgtt ttctggcaca cgatttttag ttttaacaga atctgtaacg ataatttctt
     1501 tgattggagc tgtttctaat acctcagcag ctccaccagc aaataagcca tggctagcga
     1561 ccgcgtaagt atcagtagcg cctgagcgtt caagaatttt agcagcttct gcaaaggttt
     1621 tcccagtatt taaaatatca tcaattaaaa tggctttttt accagaaaca tcaccaataa
     1681 tataaccttg ttcacgttca gaatcatctt gtgcatagtc gataatagca atcggggaat
     1741 caagatattc agccaagctt ctagcacgtt taattccaga atttttaggg ctaacgacaa
     1801 caacatcaga acctgataag cctaatttac tgtaacgttc tgcaaaaaga gggactgtaa
     1861 agaggttatc cactggaata tcaaaaaaac cttgtacctg aacagcatgt aagtcaagcg
     1921 tcactacacg atcaatacca gctttagtca gcatattagc tactagttta gcagtaatcg
     1981 gttcgcgggg cttagcgaca cggtcttgac gagagtaacc aaagtatggc aatacaatat
     2041 tgacggtatt agcacttgca cgtttacaag catcaatcat gatgagtaat tcccaaagat
     2101 tatcattgac aggaaaacta gtggattgaa taatatagat atcatctcca cgcactgttt
     2161 cttcaatatt gatcataatt tctccatcgg aaaattgacg tgaagacatt tttccaagag
     2221 ggattccagc agctttagca attttttcag caattggaag atttgatgtg agtgagaaca
     2281 gtttgatttg cttgtcagca tatcgttcag tcatgataga tttagctcct taacttcaat
     2341 aaaattgggt aaactgtttt attaatgagt cacattaccc aaaagtgttt aattgacatc
     2401 cctattttaa cagaaaaaca gaaaaatttc agtttttctg tcgcttttag ccattattta
     2461 tcgttgaact tttttaaggt gttaatacac cgagctactt tgcttttagc atatttgaaa
     2521 gctatgtgat gttcagataa aaaagaatca aaatcaatct ttccttgaag agcgtcactt
     2581 acttctaatt ctaattcata gtctttggta ttggcatata ggttatagtc taaggccaat
     2641 ttacctatcg gtatcactgt ctcgcgacga acggtagtta aattgccaaa agttaccagt
     2701 gcagatggtt tgataccttt tgaaataata atatcaagag cagttgattc aggaagattc
     2761 ccatgtttaa tcatatcttt tgcttgttca agaaaaagag ggacattgta ctcacgattc
     2821 cccacttttt ctggcacttt taaggttaat tcggcgctat ttgcaaatgt tcgaatacgt
     2881 aatgacattt tgttagcttt taaatcaaat gcttttgtat caatatagta attagtttgt
     2941 gtaacaggcg tcacatgttt catttgagat aaaagacggt tatactcatt ttttgtaagt
     3001 agagttttat attcgatttc taggttagtc atgggaaatt ccttttaatt tgtgctataa
     3061 taaattgtta tttcaatttt atattattat cctggctttg acaagaaagg agacaataga
     3121 tgaccttaga ttgggaagaa tttttagatc cttatatcca aacagttggt gaattaaaaa
     3181 taaaactacg gggtattcgc aagcaatatc gtaagcaaaa tcgttattct ccgattgaat
     3241 ttgttacggg acgtgttaag tcaattgaaa gtattaaaga aaaaatgatt ttacgtggtg
     3301 ttattgaaga aaatatagca caagatattc aagatattgc tggactacgt attatggttc
     3361 agtttgtcga tgatgtggaa gaagtcttag ctctattgcg tcaacgacaa gacatgacaa
     3421 ttgtttatga acgagattat attcgcaata tgaagtccag tggctacagg tcttatcatg
     3481 tggtggttga gtaccctgtt gacaccattg aaggtcaaaa aaaggtctta gcggagattc
     3541 agattcgtac tttggcaatg aacttttggg cgaccattga gcattcttta aattataaat
     3601 atggtggaga cttcccagaa gaaattaaaa agcgtcttga agtgactgct aaaattgctt
     3661 tagaattaga cgaagaaatg cgtaagattc gagaagatat tcgagaggct caattattgt
     3721 ttgaccccgt gacacgaaat ttaagtgatg gtgtaggaaa tagtgatgac acagatgaat
     3781 tatacaggta aggtaaagcg agttgctatt attgcaaatg gtaagtacca aagtaaacgc
     3841 gttgcctcca aacttttctc cgtatttaaa gatgatcctg atttctatct ttcaaagaaa
     3901 aatccggata ttgtgatttc tattggcgga gatgggatgc tcttatctgc ttttcacatg
     3961 tatgaaaaag aattagataa ggtacgtttt gtaggaatcc acaccggtca tcttggcttt
     4021 tataccgatt atagggattt tgaagttgat aaattgattg ataatttaag aaaagacaag
     4081 ggagaacaaa tctcttatcc gattttaaaa gttgctatta ctttagatga tggtcgtgtg
     4141 gttaaagcgc gtgctttgaa tgaagcgacg gttaagcgta ttgaaaaaac gatggtagca
     4201 gatgttatta ttaaccatgt caaatttgaa agcttccgag gtgatgggat ttcagtatcg
     4261 accccgacag ggagcacagc ctacaataaa tctttaggtg gtgctgtctt gcatccgacg
     4321 attgaagcgc tgcaattgac ggaaatttcc agtcttaata accgtgtctt tagaaccttg
     4381 ggctcatcaa tcattattcc caaaaaagat aagattgagt tagtgccaaa acgattagga
     4441 atttatacca tttccattga taataaaacc tatcagttaa aaaatgtgac gaaggtggag
     4501 tattttatcg acgatgagaa aattcatttt gtttcctctc cgagtcatac gagcttttgg
     4561 gaaagggtca aggatgcctt tattggagag actgactcat gagatttgaa tttgtagcag
     4621 acaaacgaat aaaagtaaaa acccttttaa aaagtcatga tgtctctaaa ggactattgg
     4681 ctaaaatcaa atataagggc ggtaatatat tagtgaatgg tattgaacaa aatgccattt
     4741 atttattgca agtgggagat gttgtcacca ttgacattcc aaacgaagag ccctttgaaa
     4801 agcttgaagc catccctttt gatttggata ttgttcacga ggatgatcat tttttggtga
     4861 ttaataaacc cattggcttt gccagtattc caagtgccat ccactccaat accattgcta
     4921 actttatcaa ggcatattat gtggacaatc attacctaga ccaacaagtg catatcgtga
     4981 ctcgtttaga cagagatacg agtggcttga tgttatttgc taagcatggt tatgctcatg
     5041 caaggttgga caagcaactc caaactcgct caatagagaa acgttatttt gctctggttt
     5101 ctggaaatgg gacgttgcca gatgaaggag atattattgc tccaattggg cgttcaaaag
     5161 atagtattat taccagggca gttgacccta tgggcaaata tgccaagact agctataagg
     5221 ttgtggcgcg ctattcagaa aatgtgcatt tagtggatat caaattgcat acaggacgta
     5281 cccatcaaat cagagttcat tttgcccata ttggttttcc acttttaggg gatgaccttt
     5341 acggaggtcg tttggactta ggaataacaa ggcaagcttt acattgtcat tatttgaatt
     5401 tcaaagatcc atttacagaa agtgattgta gctatgcaat acacttgaca gatgactttg
     5461 atagcgttat cataggttta cagaaaaaag atagaggtta ttaaagaatg agtattcgta
     5521 gtttattcgg tggtttaaga gaaaaaattc ttggtaaaaa catgaagatt gttttcccag
     5581 aaggtaatga tgagcgcgtc gtccgtgcag ctgctcgttt gaaatttgaa ggactcttag
     5641 aaccgattat ccttggacag tcagaagagg tacgcaacct tttgacaaaa ttaggtttcg
     5701 ctgatcaaga ctatactatc attaatccaa atgaatatgc ggattttgac aaaatgaaag
     5761 aagcttttgt tgacatccgt aaaggaaaag caacgcttga agatgctgat aaaatgcttc
     5821 gtgatgtgaa ttactttggt gttatgttgg ttaaaatggg attagcagat ggaatggtat
     5881 ctggtgctat tcattcaaca gctgatactg ttcgtccagc ccttcaaatc attaaaacca
     5941 aaccaggtat ttcaagaact tcaggtgttt tcttgatgaa tcgcgaaaat acgagtgagc
     6001 gttacgtgtt tgctgattgt gctatcaata ttgacccaac agcacaagaa ttggcagaaa
     6061 tcgctgttaa cacagctgaa acagctaaaa tctttgatat tgatcctaaa attgctatgt
     6121 taagcttctc aacaaaaggt tctggtaaag cgcctcaagt tgataaggta agagaagcaa
     6181 cagaaattgc taaagggttg aaccctgatt tggcacttga tggtgagttg caatttgatg
     6241 cagcctttgt tcctgaaaca gcagctatca aagcaccaga ttcagcagtt gctggtcaag
     6301 ctaatacttt cgttttccct gacttacaat ctggaaatat tggttacaaa attgcacaac
     6361 gtttaggaat gtttgatgct attggaccaa tcttacaagg attgaacaaa cctgttaatg
     6421 atttatctcg tggctcaagc gctgaagata tttacaaatt agctattatt acagcagcac
     6481 aagctattga aagccaaggg taacttaaga ccccttgata taggattcta accgctaagt
     6541 gatgtgttag aagttgtcct aagactaatt gacattatta aaaacgagtt ggccagacca
     6601 tctcgttttt ttgaaggtga ggaaatgtat gggaaatatt gccttagtaa caggggcttc
     6661 agccggtttt ggcagagcca ttgtcgaaca cttaattgca gatgggataa aggttattgg
     6721 tgccgctcgt cgtcttgaga aactcaaggc cttagaaacg agctttgggt cggacaactt
     6781 ttaccctttg cagatggatg tcacagatac caaagcgatt gatgatgctt tgacaagtct
     6841 accaaatcag tggcaagata ttactatttt agtgaataat gcaggcttgg cattgggact
     6901 tgataaggct tatgaagccg attttgagaa ttggatgacg atgattaata ccaatattgt
     6961 tgggttgatt tatctcacac gtcaattatt accacatatg gtctccaaag atgctggtat
     7021 tattattaat ttagggtcaa ctgcagggac aattccctat ccgggagcta atatttatgg
     7081 ggctagcaag gcttttgtta agcagttctc actcaattta cgagctgatt tagcaggtag
     7141 ccatatacgt gtgaccaata ttgaacccgg tctatgtgaa gggacagaat tttcaaaggt
     7201 tcgctttaat ggtgatgagg cacgggtgaa ggccatttat caaggagcac atgccattca
     7261 acctcaagat attgcgtcga ctgtatcatg ggtgattcat cagccccctc atgttaatgt
     7321 taatcgtatt gagctgatgc cagtgtcgca aagttatgga ccgcaaccag ttagtcgtga
     7381 ctagcaaggg atgagtccat aagaataata atctttagaa aaatggttta ctggtatgga
     7441 ttattcttta taagtgagac ttaccgattt agtcatcaaa aaaagcaatc aagaagaagg
     7501 ttttgaggtc ttcaagcgtt catgattgct tcttgtgcgt tgatgattta ggctgaactc
     7561 cctatttaaa atcaagttta gtgatctaaa atggaagggc ctgatgtgac atcggaccag
     7621 ccaacaatgg cttgtccagt ttcttctaaa tactggttta ataacggttt aatgtcttga
     7681 acggtatcca aaactcccac cagctgacct tgaggatttt taagagcttg ataatgctgc
     7741 atgtaaatat gatccaatga acccgaagga agtaggaagg ttttacaagg gctatctgat
     7801 aaacgcaatt cagcaagaat ccaatcttct atttcgttat cagtagttgg caaaaaactt
     7861 ccattaaaag catgattatc gactagaatg ttcccctttg catcagataa ccttgcttgc
     7921 aaaggaaggt actgtaaaaa atatccatca aatttttggt aaaatctagt gaggtattgg
     7981 cttaacaata agactgttgt tgcttgatca aagacacttt ctgtcactaa aaagccctga
     8041 ccatgttgag aggttttgaa atagagtgta ggcaagtcaa tgtcatgctc atggaaactg
     8101 aaaattcctt ggaaagtcga caattgattt gactgaatgt tggctttgct agtgagaata
     8161 gtcacctcaa aaaggtgtga gaagtggtgg gaaagctctc taataaacgt atcttcaagt
     8221 tggttttcag gtgttaagag cgctaaaatg gaaatggcat ttttcataat tgtatgatag
     8281 ctgtattttc tagaaaagac aattaatctg cttatctatc atcataggca agtctaggat
     8341 ttttgataag gtaattttgg agagataggc tgacaaagtg acctgttttt ctataagggg
     8401 taaggaggaa tagtctcatt atttgactta tagtgggaaa ctttttataa tggtcaacaa
     8461 caaacgacaa gaaaataatg agagaaaatg tttttgagaa ttggtagttt ttaccttact
     8521 gaggatacct aagagtccct ttaattagta gatgcgtttg tctaaaaatg gaagtgcctg
     8581 cagtaattcc ttgtagatac ttagaacgtt ttgagaaaaa atgacagaga tacaggttga
     8641 atgaactcat cagcttttat gctgttgctt taaccaatga attggagaga taatgatacg
     8701 ttttaataat gtttctaaaa cttttggtca gacaaaggtt ttgcaagagc agacctttca
     8761 aattaatgac cgtgaatttt ttgtgctggt tggccccagc ggatcgggca agaccacact
     8821 tttaaaaatg attaattgcc ttattgaacc aagctctgga gatattttac taaataacgt
     8881 cccacagaaa gagttagatt tacgtgagat gaggctatct attggatacg tattgcagca
     8941 aattgctctg ttccccaatc tcacagtagc tgaaaatatt gcgattatcc ctgagatgaa
     9001 gcaatggtca gctgaagaaa ttagacaaaa aactgaagaa ttattggata aggtgggcct
     9061 acctgctaaa gattatcttg atcgttaccc aagtgattta tcgggaggtg aacagcaacg
     9121 tattggtatt gtacgtgcta tcatttctca tcctaaaatt ctattgatgg atgaaccatt
     9181 ttcagcctta gatcctattt cacgtaaaca attgcaagag ttaatgttga gtcttcacaa
     9241 ggaatttgac atgacgattg tatttgtgac acatgatatt gatgaggcca ttaaattagg
     9301 agaccgtgta gctattttaa atgagggaga aattgtgcaa ctggatcgcc cagaaatgat
     9361 taagacccac cctgctaatg cttttgtggt caatttattt ggaggtgatg agcatgccta
     9421 gtttgtttgt aactttccaa aaccgtttta atgaatggct ggcggctctg ggggaacacc
     9481 tgcaaatttc ccttttatct cttatgatcg ccttgctaat aggtgtgcct ttagcagccc
     9541 ttctcagtcg cagcaaacgt tggtcagaca ttatgttaca ggtaacaggt gtttttcaaa
     9601 ccattccctc actggctttg cttggtcttt tcatcccttt aatgggaatt ggaacgttgc
     9661 ctgcagtgac agctttagtt atctatgcga tttttccgat tttacaaaac accatcacag
     9721 gattaaatgg tattgaccca agtctcgtgg aagcaggaat agcttttggg atgaccaaat
     9781 gggagcggtt aaaaacgttt gagattccaa ttgcaatgcc tgttattatg tcaggtgtgc
     9841 ggacgtcagc agtcatgatt atcggcacag ctactttagc ttccttgata ggagccggtg
     9901 gacttggctc tttcatctta ttggggattg atcgtaataa tgctaacctg attctgatag
     9961 gggctatttc ttcagctctg ctagctatta ttttcaatag tttgttacag taccttgaga
    10021 aagcttcctt gcgacggatt atgattagtt ttggaatcac cttacttgca ttgctagcat
    10081 cgtatactcc tatggcgctt agtcagtttt caaaaggaaa agatacagtg gttattgccg
    10141 gtaaattggg agcagagccc gatattctga ttaatctcta taaggaatta attgaagacc
    10201 aatcagatat aagtgttgag ttgaaatcta attttgggaa aactagcttc ttatatgaag
    10261 cccttaaatc tggagatatt gatatgtatc ctgaatttac aggaaccata acatcaagtc
    10321 ttttacgcga caaaccacct ttgtctaatg accctaagca ggtctatgag gatgctaaaa
    10381 aaggcattgc taagcaagat aaactgaccc ttctcaagcc atttgcttac caaaatacgt
    10441 atgctgttgc tatgccagaa aaattggcta aggaatatca gattgaaacc atttctgatt
    10501 taaaagcgca tgctgatact ttaaaggctg gttttacttt ggaatttaag gacagagcag
    10561 atggctataa gggaatgcaa tctcaatatg gattacagct atctgtggcg acgatggagc
    10621 cagctcttcg ttatcaagca attcaatcag gagatatcca agtaacagat gcttactcta
    10681 cggatgctga aattacgaaa taccatttga aagttttaaa ggatgataaa cagttgtttc
    10741 caccttatca gggagctcct ttgatgaaaa cttccttatt aacaaaacat ccagaattaa
    10801 aaggcattct taatcaatta gcgggaaaaa ttactgaaaa agagatgcag gacatgaact
    10861 acgaggtatc tgttaaagga gcagatgcta ataaggtcgc tcgagattat ctgttgaaaa
    10921 caggcttaat ccagaaataa acagaaatgt tggtccgtag gactggcatt ttttcgtctc
    10981 ttaagttcaa gaagtaacaa ttcataaaca caaaaaccga actttaaaat taaaaatagc
    11041 atataaattt gacaaaacat aaacaaataa gtaatctata aaatgaaagg taagttttta
    11101 cctaaagata cctctaatca tcagaggtca taggaagatt attttgtata gaggacttag
    11161 agaagaaggt gagaactaac ttgtttttct taatctatgt taaaagagga gaaacttatg
    11221 tttaatgaca tccctgtatt tgattatgaa gatattcaac tgattcctaa caagtgcatt
    11281 attactagtc gttcacaagc agatacaagt gtgacactcg gaaaatacca gttcaagcta
    11341 ccagttatcc cagcaaatat gcaaaccatt attgatgaaa caattgctga gcagttggca
    11401 aaagagggtt atttttatat tatgcatcgt tttgatgaag atagccgcaa accttttatc
    11461 aaacgcatgc atgaacaagg cttgattgca tccatctctg ttggggttaa agcttacgaa
    11521 tatgaatttg tgacttcttt gaaagaggat actcctgagt ttatcaccat tgatattgct
    11581 catggtcatg ctaacagtgt tattgatatg attaagcata tcaaaactga attaccagaa
    11641 acatttgtca ttgctggaaa tgttggtacg ccagaagctg tacgagaact cgaaaatgca
    11701 ggtgctgatg ctactaaagt aggcatcggt ccaggcaaag tatgtatcac taaagttaaa
    11761 acaggtttcg gtacaggtgg ttggcagtta gcagcactgc gctggtgcgc aaaggcagct
    11821 cgtaagccta tcattgctga tggtgggatt cgcacacatg gtgatatcgc taaatccatc
    11881 cgctttggag ctagtatggt catgattggt tcgctttttg cagggcatat tgaaagtcct
    11941 ggaaaaacag tagaagtgaa tggtgaaacg tttaaagaat attatggctc ggcgtcagca
    12001 tatcaaaaag gcgagcataa aaatgtagaa ggcaaaaaaa tcttattgcc tacaaaaggt
    12061 cacttatcag ataccctgac cgaaatgcaa caagatttgc aatcgtccat ttcttacgcg
    12121 ggtggtaaag atttagacag tttgcgtcat gttgattatg ttatcgtcaa aaattctatt
    12181 tggaatggtg attccattta aatgatatgg agttagctag gaccagtaaa gcatttttta
    12241 gcttaatgct ggagatgctt ttatcatatc tctgtaggta ttgaaaaaaa taagaaacat
    12301 ggtaaaatag taaattatca taatgaattc aataatgaca tacttattta tgctgtgaat
    12361 tggcgcagcg tctctacaag acaccttaat gtctaacaat aagtaagctt ttaggcttgc
    12421 ttggttttta accttgcaaa gtgagaaact cttatagttt ctggctttgc ggcaggcttt
    12481 ttctatttga atcaaaagga gatttatgca gttacttgaa gaacgtatct taacagatgg
    12541 caatattcta ggagagaata ttctaaaggt agataatttt ttaactcatc aagttgatta
    12601 ccggttgatg aaagcaattg gtaaagtgtt tgctcaaaaa tatgctgagg ctggcattac
    12661 aaaagtggtt acaatcgaag cttcaggtat tgcaccagcc gtatacgctg cagaagcaat
    12721 ggatgttcct atgatttttg cgaaaaaaca taaaaacatt accatgacag aaggcatttt
    12781 gacagcagaa gtttattctt tcactaaaca agtgacgagc acggtgtcta tcgctggtaa
    12841 attcctatct aaagaagaca aggttttgat tattgatgac tttttagcta atggtcaggc
    12901 agccaaaggc ttgattgaga ttattggtca agcaggggca caagtcgtcg gcgttggtat
    12961 tgtgattgag aaatctttcc aagatggtcg tcgattgatt gaagatatgg gcattgaagt
    13021 gacctcatta gcccgtatta aaaactttga aaatggtaat ctaaacttct tggaggctga
    13081 cgcataatga cacattcaac aaagcaggaa cattctcact cgcaatcagc tgtccttggc
    13141 ttacagcatg tgctttcgat gtatgccgga tctattttag taccaattat gatcgcaggt
    13201 gctttaggtt attccgctag agagttgact tacctgattt cgacagatat tttcatgtgt
    13261 ggtgtggcta cttttttaca gttaaagtta accaagcata caggagtagg gttaccagtt
    13321 gttttaggct gtgcttttca atcagtggca cctctatcca ttattggagc gcaacaaggt
    13381 tcaagtgcca tgtttggagc cctcattgcg tcaggaattt atgtcagttt agtggcaggt
    13441 attttttcta agattgctcg tttcttccca ccaattgtta caggatcggt cattaccgtt
    13501 attggcttaa gtctcgtagg tgttgctatg gggaatatgg gagataacgt caaagagcct
    13561 acggcacaaa gcatgatgtt atcattgttg acgattgtca ttattctttt agtccaaaaa
    13621 tttaccaaag gttttgtgaa atccatttcc attttgattg ggcttgtagc gggaactttg
    13681 gtttcagcca tgatgggatt agtagataca actcctgttg tagaggcttc ttggattcat
    13741 gtgccaaccc cattttattt tggcatgcca acttttgaaa tcacttctat tgtgatgatg
    13801 tgtatcatcg caacggtttc tatggttgaa tcaacaggtg tctacttagc gctttcagat
    13861 ttgactaatg atcaattaga tgaaaaacgt ttgcgcaatg gttatcgctc agaagggatc
    13921 gcagtctttc tcggtgggtt atttaatacc ttcccttaca ctggtttttc tcaaaacgtt
    13981 ggacttgtcc aaatctcagg tattaaaacc cgtcgtccga tttactacgc agcaggtatc
    14041 cttgtgatca ttggcctact ccctaaattt ggagcaatgg cacaaatgat tccaagccca
    14101 gttcttggtg gagctatgct tgttctcttt ggtatggttg ctcttcaagg aatgcaaatg
    14161 cttaatcgtg ttgatttcca aaagaacgag tataatttta ttattgctgc cgtttccatc
    14221 tcagcaggtt taggctttaa tggcactaat ctttttgcca gcttaccaga gacagctcaa
    14281 atgttcttaa cgaatggtat tgtgatcgca accttgacat ctgttgtctt aaatttagtt
    14341 ttaaatggca aagataaaca agatgaataa ttaaaaaacg gctaattgag ccgttttttc
    14401 tgtgatcagt tttgagcaaa ccgttaaccc cttttaatga tagtatggtt gaaaatagtg
    14461 tctcaaacca tttgacataa ggacatggtg ctttcttgtt actagaagac cttcaatatt
    14521 atcaaaggtg tttaaaagtg tgataatcat tgagctatca agaccaaata aacgggtagc
    14581 ccatatgtca caataaaaag aagaaggagc catgatcgtt aagctaagca tatctgtttc
    14641 tatagggcag cctgtctgac gatctaagat atgatgatac tgtttccctt tggatgtaaa
    14701 ctgcctttca taaattccag aagtcacaac agagtgattg ttaaccttga tgacaccaag
    14761 atgttgccca cgtttagcat ctggtttttg aataccaatt cgaaaagtct tgtcagggct
    14821 tttcggatta ggtccatgaa cgcgtacatt tccacctaaa ttaataaggg cagagtcaat
    14881 accatcttca atcaggtagg ccataatctt atcagtaata taaccttttg ctaaggctcc
    14941 taagtctaaa gccattccta cttgttgtaa aaagacagtc tgttttttgt catctataag
    15001 aacctgtcta ggatctgtta gagctaactg ttgtgagata aggttatgac taggcactct
    15061 agcatcttca aatccaattc gccaggcttg aacaagtggc ccaatggcga tattaagatt
    15121 acttggtgtt gacaagctat gagctttacc aatttggatt aggttaaata aatcagagtg
    15181 aacgctgacg ggtttaacac cagccacctg attaatagcc atcaattcag agtttgaatc
    15241 attagctgaa aaacgatttt tgtaagtata taataagtca atgactctac ttagttgttg
    15301 gcaagctttg tcagattcga tctgaatatc aataactgtt cccattagct ttaattgttg
    15361 cgtaacaaac ataattagtc ctctttttag cagaataccc ccactaagga gtgggggaag
    15421 gtcattatga tttttgtttc atttcacctt gaggatagta agttccttca ggcatatcgt
    15481 tgataaaaac atggatattt tctttaggtg cttttgcaat gcgtgagact acttcggtaa
    15541 cctcgcgagc taattgattt ttttgttctt gtgagcgtcc ctcaaacaag tcaattgtta
    15601 caaatggcat aatgttactc ctttatgtta ttgggcatca ttgtaacata atgctgtgaa
    15661 aaagtataca ctgttttcaa tggctgggaa aacttcagcc tttgtggtaa aataggtaga
    15721 atactataga aagtaggatt ttccgctttg gctcaactct attataaata tgggacaatg
    15781 aattctggta aaaccattga aattttaaaa gttgctcata actatgaaga acaaggcaaa
    15841 cctgttgtca ttatgacaag tgctcttgat acacgtgatg gttttggcat cgtctcaagc
    15901 cgtattggta tgcgacgaga agctatcccc atttcaaatg acatggatat tttcacattt
    15961 attgcccaat tggaggaaaa accttattgt gtcctgattg acgaaagcca atttttaagc
    16021 aagcaaaatg tttatgattt ggcgcgtgtg gtggatgagc taaatgttcc tgtcatggct
    16081 tttggtttga aaaatgattt ccaaaacaat ctttttgaag gttcaaaaca tttgctatta
    16141 ttggccgata agattgatga aatcaaaaca atttgccaat actgtagtaa gaaagcaacc
    16201 atggttttaa ggacagaaaa tggaaaacct gtctatgaag gtgatcagat acaaattggt
    16261 ggtaatgaaa catatatccc agtttgtcga aaacattatt ttaatccaga gatttaaaag
    16321 gtaatcggtt ttaaaggaga tacaaagaaa aatgaatatt tatgatcaat tgcaggcagt
    16381 tgaagatcgt tatgaagaat taggtgagtt acttagtgat ccagatgttg tttcagatac
    16441 aaagcgattt atggaattat cacgtgaaga agctaatact cgagaaactg tcacagctta
    16501 tagagaatat aaacaagtca ttcaaaccat ttcagatgct gaagaaatga tcaaagatgc
    16561 cagtggtgat cctgaattag aagaaatggc taaagaagaa cttaaagaat caaaagcagc
    16621 taaagaagag tatgaagaaa aattaaaaat ccttctatta cctaaagatc ctaacgatga
    16681 taaaaacatt attctagaaa ttcgtggtgc tgctggtggc gatgaagcag cgctttttgc
    16741 tggtgatctt ttaacaatgt atcaaaaata tgctgaaact caaggatggc gttttgaagt
    16801 tatggaatca tccgttaatg gtgttggtgg tattaaagaa gtggttgcca tggtttctgg
    16861 tcagtcagtt tattctaagc ttaaatatga atcaggagct catcgtgttc aacgtgtccc
    16921 ggtgacagag agtcagggtc gtgttcatac gtcaactgca actgttttgg taatgccaga
    16981 agttgaagaa gtagaatacg acattgatca aaaagacctt cgcgtcgata tttaccacgc
    17041 gtctggtgct ggtggtcaga atgtcaataa agttgctact gcagttcgta tggtacacat
    17101 tcctacagga atcaaagttg aaatgcaaga agaacgtact cagcaaaaaa accgtgataa
    17161 agcgatgaaa atcattcgtg ctcgtgttgc tgaccatttt gcgcaaattg ctcaagatga
    17221 acaagatgct gaacgtaaat caacagttgg tactggtgat cgttcagaac gtattcgtac
    17281 ttataatttc ccacaaaatc gtgtaacaga tcatcgtatt ggtttgacac ttcaaaaatt
    17341 agatactatt ttatctggaa aaatggatga agttattgat gcactcgtta tgtatgatca
    17401 gacaaagaaa ttagaatctc tcaataacta atgaactatg ctacattaat cagaacttat
    17461 gaagataaac tagaacaaat agatgaggat cgcgaaaatc tcgcctatgt ttttagagaa
    17521 atcaaagaat ggtcaagtct agatatgttg attcaccaaa atcaagctgt gactcctgaa
    17581 gatgctgttc ttttggaaca tattttctgt tctctaagtc agcatttatc tcctcaatat
    17641 attacaggta atgcttattt tcgtgatttg aagcttgcag tcgacaagcg tgtattaatt
    17701 ccaaggccag aaacagaaga attagttgac atgattttag ctgaaaatct tgatgcaccg
    17761 ttgaatgttt tagatattgg tacaggtagt ggagcgattg ctatttctct caaaaaagaa
    17821 aggcctaact ggcaagtaac ggcatctgat atttctagag ctgctcttga cttggcaaaa
    17881 gccaatgctg atgcttacca gcttgatata acgtttattg aatcagatgt ttttagtctc
    17941 atttcaggaa catttgatat tattgtgtca aatcctccct acatatccta cgaggataag
    18001 gaagaagtca gtctaaatgt tttgcaatca gagcctcatt tggcactttt tgctaaagaa
    18061 aatggctatg ctatttaccg taagattatt gaacaagctg acaattactt aactaaggag
    18121 gggaagcttt actttgaaat tggttataag caagctgaag gtataaaaga tatgttacaa
    18181 gcctattttc ctcaaagaca tatacgagtc gtaacggata tatttggcaa agaaagaatg
    18241 gtggttgttg attatggagt atctagctag tatcattgaa tcaggtgatg cccttgtttt
    18301 gccaacagaa acggtttatg gtctttttgc caaggcttta gatgaaaaag cagtaaatgc
    18361 tgtttatgac ttaaaacaaa gaccccgaga taaagcaatg aaccttaatg tggctgattt
    18421 taatagtatc ttagtctttt caaaagaaca gccgagatac ctcaagaaat tataccaagc
    18481 ctttttacca ggtccgttaa cgattatttt aaaagctaat gaccaggttc cttattggat
    18541 taattcgggt ctttcaacgg ttggttttcg cttacccagt catccaatta ccacagcttt
    18601 aattcaaaaa acaggccctt taattggtcc ttctgcaaac ttatctggca aagctagtgg
    18661 tcgagttttt gatcatatta tgcaagattt tgactttcaa gtgtttggtt atgcagatga
    18721 tccttttcta acaggtaagg attcaaccat cttagactta tcaggtgagc gtgctgtgat
    18781 tttacgtcaa ggtgctatca ccaaagaaga attattagcc aacgtgcctg aacttcgctt
    18841 ttaagagagg agccgcttgg aatgttgaga ccattaagta aaacggactg tcctatgcta
    18901 caagaaatta acgccaaagc ccttggctat ttagtttcgc ttgacttgtt agaaaggcaa
    18961 tatgaacgat tgattgagga ttgccatcac tattttttag cttatgccga caaggatacc
    19021 aatcaattat taggctatgt tcacgctgaa cggtatgaga ccctttatgc ttctgatggt
    19081 cttaatctct tgggcttggc tgttttacca gcctatcaga gaaggggaat tgggagtgcc
    19141 ttactaaggg ccctggaatc ccaagctagg caggaaggca ttgcctttat tcgcctcaat
    19201 tctgccagtc atcgtaaaga agcgcatgct ttttaccgaa acctcgacta tgcagatgat
    19261 aaaacacaat tacgattcat caaaaactta caaggagatg acaatgattt ttgataaagg
    19321 taatgttgaa gactttgata aagagctttg ggatgccatt catgctgaag aagaaagaca
    19381 agaacatcat atcgaattga ttgcatctga aaacatggtt tcaaaagctg tcatggcagc
    19441 tcaaggttct gttttaacca ataagtatgc agaaggctat ccaggtaatc gctattatgg
    19501 tggaacagaa tgtgtggata ttgtcgaaac gcttgctatt gaacgtgcta agaaactttt
    19561 cggtgccgca tttgccaatg ttcaagccca ttccggaagt caagccaatg cagcagctta
    19621 tatggccttg attgaggctg gtgacaccgt attaggaatg gatttggctg caggtggtca
    19681 tctcacgcat ggctctccag taaatttttc tggaaaaacc taccattttg tgggttactc
    19741 agtagatgct gatactgaaa tgttaaatta tgaggcgatt ttagaacaag caaaggcggt
    19801 ccagccaaag cttatcgttg caggggcttc ggcctactct agaagcattg attttgaaaa
    19861 gtttcgtgcc attgctgatc acgtaggtgc ttacttaatg gtggacatgg ctcacatcgc
    19921 tggccttgta gcagcaggtg tgcacccgag tcctgtccat tatgcgcata ttgtgacatc
    19981 aacaacccat aaaaccttac gtggtcctcg tggaggcttg atattaacca atgatgaagc
    20041 tcttgctaaa aagattaatt cggccgtttt ccctggttta caaggaggac ctctggaaca
    20101 cgtgattgct gccaaagcgg ttgccttcaa agaagccttg gatccagcct ttaaagacta
    20161 tgcacaagct attattgata atactgcggc tatggcagca gtttttgcac aagatgatcg
    20221 tttccgtctg atctcaggtg gtacagataa tcatgtcttt ttagtagatg tcactaaggt
    20281 tattgctaat ggtaaactag cgcaaaatct tctggatgag gttaatatta ctctaaataa
    20341 aaatgccatt ccttttgaaa ccttatctcc ttttaaaaca tcaggcattc gtattggttg
    20401 tgcagctata accagtcgtg gcatgggagt taaagaaagc caaactatcg ctcacctcat
    20461 catcaaagcc ttggttaatc atgatcaaga aactattctt gaagaggttc gtcaggaagt
    20521 gcgtcagtta accgatgcct tcccactcta taaaaagtaa ggaatcatgt tagatagtta
    20581 tataaaacgt attgtcattc atcaattttc tcccaatgac actgagttac tgttatcaga
    20641 tcgtttagtg agcattacac cacgaattga tgaatatttc cggaaaaaat tggctaaagt
    20701 gttctcggat gaagccaaac ggggtcagtt tgaggctaat aatacctttt ttacaaccat
    20761 tggtgatgat ttgttggaaa cgtctgttac cattgcccag ttatggaagg aagcctttgt
    20821 tatttcagag gatcaaaaaa ccaatgattt agtctttgtc cagtttgata aggatggcga
    20881 accctttttt gctttcttgc gaattgcttt gaaagaacag tttgctcacc tttctgacaa
    20941 ttatgaacat ccatttacgg tgacgcagaa taatctgccg agtcccaccc agacaccaga
    21001 tgaagcacta gtcattaatc tcaaatctgg tcagtactac ttgattgaaa agcgtgtgaa
    21061 gcataatggc agttttgcta attatttttc agaacacctc ttgaaagtta cacctgagca
    21121 atctgttaaa aagtctatca aaatgataga acaaaccgct caaaaaattg cagagcattt
    21181 taatcaagat gattttactt ttcagtcaaa gatgaaatcc actcttttta agcagttaga
    21241 agcagacgac gttttatcac cagaaaaatt agctgaccaa ctctttgatg ataatttaac
    21301 agcccgttta acctttgtgg atcaagtcaa agatgtcatt ccagaaccta taaaaattag
    21361 cgatattgat cattctagac agataaaaaa actagaaaat caaaagctat cgttatcaaa
    21421 cgggatagaa ttaacagtac caaatgccat ttatcaggat gctgaagcgg ttgaattttt
    21481 gttaaatgat gatgggactt attcaatctt gattaaaaat atagaggata ttaaaaccaa
    21541 atagatgttt agacttttaa agcgtgcctg cagttttctt cttctttttg tcatttatca
    21601 atcctttgtt attcatcaca atgttcaacg tgttttggca tataagccta tggttgagaa
    21661 aacattagca gaaaatgata caaaggcaaa tgtagactta gtcttagcta tgatatacac
    21721 cgagacaaaa ggaggagaag cagatgtcat gcaatccagt gaaagcagtt caggacaaaa
    21781 aaactcgatt acagatagtc aggccagtat tgagcacggg gtgaatttac tgtctcataa
    21841 tcttgctcta gctgaggaag caggagtaga ttcttggacg gctgttcagg cctataattt
    21901 tggaacagct tatattgatt atattgctaa acatggaggt caaaataccg ttgatttagc
    21961 gactacctat tccaaaaccg ttgtggcgcc aagcctaggc aacactagtg gtcaaaccta
    22021 tttttattac caccccctcg ccttgatttc tggaggtaag ctttataaga atggcggcaa
    22081 tatctattac tcacgagaag ttcatttcaa tctttattta attgaactga tgagcctttt
    22141 ttagaaagtt atcatgaaac gattacgtcc atatttgaaa gggtacctaa aagaaagtat
    22201 cttaggtcct ctttttaaat tattagaagc tttatttgaa ttattagtcc ctttgttaat
    22261 tgctaacatg attgatatat cgattagtca acacaacagc cagggaattt tgagggttgt
    22321 tttaacatta tttggtttag caaccattgg cttattgctt tccgttacag cccagtattt
    22381 ttcttcgaaa gcagctgttg gttttacaag acaaatgaca gatgatttgt ttaaaaaaat
    22441 catgtttttg agcaaggagg accaagacca tcttggttat gctagtctgg tatcacgatt
    22501 gaccagtgat agttttcaaa ttcaaactgg tatcaatcaa tttttgcgtc tttttctaag
    22561 ggcccctatt atcgtatgtg gtgctatggt aatggcttat tggattagtc caagtctaac
    22621 cctatggttt gtgatgatgg tgattgtctt actaacactt gtttttgtta tgtcacattt
    22681 attaggtccc ctttatctct taatccgccg agaaacagat cacttggttc gtttgactag
    22741 ccaacagtta caaggaatcc gagtaattaa ggcttttaat caaacccaaa aagaactcca
    22801 agcatttaag cagcaaaata tgctcttaag tcgccaccaa tatcaagctg ctaccctagc
    22861 caatgtcttg aatcctatga cttttttagt ggtcaatctt actctgttaa tcttgatttg
    22921 gcaaggaagt tggcaagtag ctcatagatc gcttagtcag ggcatgttgg ttgctttaat
    22981 taattacctc ttgcagattt tggcagaact tttgaaaatg accatgttga tgggaaccat
    23041 caatcaaagt gtaacagccg caaaacggat taatcaggtg tttgttttag ctgatgaagt
    23101 gcctttgccc ttacttaaag atggtcctat ttcaactcat ctgttgacca tccggcactt
    23161 gacctttact tatccaggag cagcagagcc aagtctgtat gatattcagt taagtgctga
    23221 tcagggagaa tggattggca tcattggtgg tactggagca ggcaaaacga ctttgattga
    23281 cttgatctgc caaacttatt cacaatatag tggtgagatt agtcttaatt ggcaaggaga
    23341 agtgccaaaa acactaaccg agtggcgaaa tgtgattgct cttgttcctc aaaaagctca
    23401 attatttaaa ggaacgatta gaagtaacct cctactggga caatcaatgc ctattaatga
    23461 tgaggagctg tggcgggctc ttgaattagc tcaagcaaaa gagtttgtcg ctgccttacc
    23521 agaacaatta gaggcacctg ttgaagcctt tggccgtcat ttttcaggag ggcaacggca
    23581 acgtctagct attgccagag cacttctgaa gccaaaaccc attttgattt tggatgatgc
    23641 cagttccgcc ttagacaatg agactcgagg acgacttttt aaagctctaa aagaagagtt
    23701 atcagatgtt ttagtgattc tagtcacgca atccattaag aatttgcagt ttgctgataa
    23761 gattttagtg ttggaacagg gccatcaatt ggattttgcc agtcatgacc agttaaaagt
    23821 aagcaatgca ctttatcaag aaatgctagc gctttacgtg aagggggagt aaaaatgatt
    23881 aaaacagacc atcacctcct aaagcgagtg cttcaggatt tgttaaaaaa acctctacct
    23941 gtttgtattc tcgtgatagc tagttttgta caagttggtt taagtgttta cttgcctgtt
    24001 cttatcggta aagccgttga tatgagtttg tcagtcaatt cttggcaaac tttaaaatgg
    24061 ctgttggggc aaatgttagt tgttattgtg gtcaacacat tgattcaatg ggtgatgcct
    24121 cttgtctata gtcgtttgct atatcaatat agccagcaat tgaaagataa gcttttggaa
    24181 aaaattcatc gtcttccttt tgcatatcta gatcgtcaaa ccattggaga tttggttagt
    24241 cgagtgataa ccgacactga gcaactgatc aatggtctac aattggtttt taaccagttt
    24301 atacttggac tattgacgat tctgtgtacc attatagcta tggcacagat tgactggctc
    24361 atgttaatct tggttttggt gttaacacca agctccctct ttttagctcg ttttattgct
    24421 caaaagagtt ttcattatgc acaagcacag accaaaagca gaggaaattt agctcagttt
    24481 actgaagaaa tccttcgtca agaaggtttg gttcaactgt ttaatgctca agagcagtct
    24541 atctgtgatt atcatgtttt aaataaaacc tattgcgagg cttcacaaaa agccattttt
    24601 tacgcctcaa cagtcaatcc agccactcgc tttattaata gtgtcattta tgctttactg
    24661 gcaggtttag gggctgttcg tatcatggct ggactttttt cagtaggtca gctaaccact
    24721 tttttaaatg ttgttgtcca atataccaaa cctttcaacg atatttcatc tgtcttggca
    24781 gagatacaga gttctttagc ttgtgcgcaa aggctttatg accttttaga tattgaaata
    24841 aaagagcaag agcactttct aacatttaag gcatcagcgg ttaagggaca aattgacttt
    24901 gaagaagtaa gtttttctta tcaaaaagac aggcccttac tgaaggatat taatttttct
    24961 gttcctgcgg gttccaaggt agcgattgta gggcctacag gtgcaggcaa atcgacttta
    25021 atcaatttac tcatgcgctt ttatgaactt gatgctggta gcatcaagtt agataaagtt
    25081 cctattaagt gttatgctaa ggaagaactt aggtccatta ctggcatggt attgcaagaa
    25141 acctggttga aagatgcgac tgttcatgag ttgattgctt acggcagtga agaggctagc
    25201 cgtggtgaag tagtggcagc agccaaagca gctcatgcac acttctttat tatgcaactt
    25261 cctaagactt atgatactta cttaagtgct tctgatgatg ctttgtccca agggcagctc
    25321 cagttattag ctattgccag aatgtttttg aaaaaaccaa aagtcttgat tctagatgaa
    25381 gccacctcct ctattgatat tagaacagaa gctgttattc aagaggcact aaaagaactc
    25441 atgagaggaa ggaccagctt tatcattgcc catcgtttat caacgattca atcagctgat
    25501 ttgattcttg ttatggatca aggtcgattg gttgagtggg gaacacatgc cagcttaatg
    25561 tcaaaaaacg gatgttatgc tagattacaa aagatagaat aaagttcgtc ttttaacaaa
    25621 ggtgaacttt ttaactcttc ctaaagttag ttaattaaca aactttaaac tgttatataa
    25681 aaaaataaca gcgaaaaagc ggacgatctt tttttataag tgagaaaaaa cagttgacta
    25741 aagaagaaat aactcaaaaa agtgagcaat atatttggaa gcgttttttg actgtggtat
    25801 aatagagccc tatataatat tgtgaaatga ggaacaaaat atatgagtaa aatcgttgtt
    25861 gttggtgcaa accatgctgg tacggcctgt atcaagacta tgttaacaaa ctacggtgat
    25921 gctaatgaga ttgttgtatt tgaccaaaac tcaaatattt catttttagg ctgtggtatg
    25981 gcactttgga ttggtgagca aattgctgga ccagaaggac ttttctattc agataaagaa
    26041 gaattagagt ctttaggggc taaagtttac atggaatcac ctgttcaatc aatcgactac
    26101 gatgccaaaa cagtgacagc gcttgttgat ggtaaaaacc acgtggaaac ttacgacaag
    26161 ttgatttttg caactggctc acaacctatc ttaccaccga ttaaaggtgc cgaaatcaaa
    26221 gaaggatcac ttgaatttga agcaactctt gaaaatcttc aatttgtgaa gttataccaa
    26281 aactcagctg atgtgattgc aaagcttgaa aacaaagaca ttaaacgtgt agccgtagtt
    26341 ggtgctggtt acattggtgt tgagttagct gaagctttcc aacgcaaagg caaagaagtg
    26401 gttctgattg atgtcgtgga cacttgcttg gcaggttatt acgaccgtga tttgactgac
    26461 ttaatggcta aaaacatgga agaacatggt attcaactag cctttggtga aacagttaaa
    26521 gaagtagctg gtaatggtaa ggttgaaaag atcattactg acaaaaatga gtacgatgtg
    26581 gatatggtta tcctcgccgt tggtttccgt ccaaacacaa ctcttggaaa tggtaagatt
    26641 gatcttttcc gtaatggtgc tttccttgtc aataaacgcc aagaaacttc tattccaggt
    26701 gtttatgcta tcggtgactg tgcaactatc tacgataatg ctactcgcga tacaaactac
    26761 attgctttag cttcaaatgc tgtccgtaca ggaattgtag cagcacataa tgcttgtggt
    26821 acagaccttg aaggaatcgg tgtccaaggc tcaaacggta tttccattta cggcttgcac
    26881 atggtatcaa ctggtttgac tcttgaaaaa gctaaacgac ttggttttga tgctgcagtg
    26941 actgagtata ctgataacca aaaacctgaa tttatcgaac acggtaactt cccagtaacc
    27001 attaagattg tttacgataa agactcacgt cgtatcttgg gtgctcaaat ggcagcccgt
    27061 gaagatgtgt caatgggaat tcacatgttc tcacttgcta tccaagaagg cgtaaccatt
    27121 gaaaagttgg cattaactga tattttcttc ttaccacatt tcaacaaacc ttacaactac
    27181 atcacaatgg cagcacttgg tgccaaagac tagtatctga taggaaaaag ccagagcagt
    27241 tcagcagcac tggctttttt gctttttaat tgttgcaacc tgaaaagttc taaacttatg
    27301 attatcctct tatagcacgt tggaaaagga atatcaggca aaacaaaaag agaccaaagt
    27361 ctcttttgtg attagttttt agcagcagaa gcaaattctt ccttagcaaa ggcttcatca
    27421 atgatagctt tcaattgatt tgcagaggct tgcatttttt gcaattcagc atcgttaagt
    27481 ggaatgttta ctggacgaac aattccatac gctccaacga tagctggttg accaatatag
    27541 caatcttcaa caccttcgta ttggccttct tggaaaacag aaagcggaag aacagcattt
    27601 tcatcatcaa gaatagcttt tgtaatacga gctagggcaa ctgcaatacc gtagaaagta
    27661 gcaccttttt tattgatgat tgagtaagca gcatcacgta cagaaatgaa aagatcaact
    27721 aggccttgct catcaatgtc acgattagct tggagccagt cgtaaagacc tacaccagca
    27781 acgttagcgt gtgaccaaac agcaaattca gagtcaccgt gttctcccat gatgtaagcg
    27841 tgaaccgaac gcgcatcaac accgatttta gcagccagag cttgacggaa acgggctgaa
    27901 tctagagatg tacctgaacc aatgacacgc tctttaggga aacctgagaa tttccatgtt
    27961 gagtaagtca aaacgtcaac tgggttagca gcaacaagaa agattccttt gaaaccagat
    28021 gcaacgattt gtgtaacaac ctctttattg atacgaaggt ttttttcaac aaggtcaagg
    28081 cgtgtttcac ctggtttttg aggagcacca gctgttaaga caacaagatc agcatcatga
    28141 cagtctgagt agtcagctgc atagattttt ttaggtgatg taaaagctag agcgtggctt
    28201 aaatcttctg catctccttg agttttttct ttaaaaatat caataatacc aagttcttga
    28261 gcaatatttt gtgttaccaa tgcaaaagcg tatgatgaac cgacggcacc atcaccgacc
    28321 aagattactt ttttgtgttg tttagttgca gtcatttcta aacatctcct taattttatt
    28381 agagcaaaag ctcatacggt cttattttaa catattgata attgtttgtc attgaattca
    28441 gaaaaataat gaaaatagtt tcctgataac gcttccaata agaaaaaata aggaatttat
    28501 ggtataatga aatctagtat tgactagaaa aggagcattc cttaaatgca agatcgaaat
    28561 ttaattgacg tcaatctgac aagtgaaatg aaaacgagtt tcattgacta tgccatgagt
    28621 gtcattgtgg caagagcttt gccagatgtg cgtgatggtc tgaaacctgt gcatcgtcgt
    28681 attctctatg ggatgaatga actcggtgtg acacctgata aaccgcataa aaaatctgct
    28741 cgtattacgg gtgatgtcat gggtaaatat cacccgcatg gggattcttc tatttatgaa
    28801 gctatggttc gtatggctca gtggtggagt tatcgccata tgcttgttga tgggcatggc
    28861 aattttggtt ctatggatgg tgatggtgct gccgctcaac gttatactga agcgcgcatg
    28921 agtaaaattg cgcttgaatt attaagggat atcaataaaa ataccgttaa ttttcaagat
    28981 aactacgatg gaagcgaaag agaaccagta gtattaccag ctcgctttcc taatttatta
    29041 gtcaatggag cgacagggat tgccgttggg atggcaacta acattcctcc tcataatttg
    29101 gcagagtcta ttgatgctgt caagatggta atggaacatc cagactgtac aacaagagag
    29161 ttgatggaag tgatccctgg acctgacttt ccgactggtg cccttgttat ggggcgctca
    29221 ggtattcata gggcttatga tactggtaaa ggttctatcg ttttacgctc tcgaacagaa
    29281 attgaaacaa ctcaaacagg tcgggaacgt attgtggtta ctgaatttcc ctatggcgtc
    29341 aataaaacga aagtgcatga acacattgtt cgtttagcac aagaaaaaag actagaaggt
    29401 attacagcag ttcgtgacga atctagccgt gaaggagtgc gttttgttat cgagattcgt
    29461 cgagaggcat ccgcgacagt tatcttaaat aacctcttta aattaacaag ccttcagacg
    29521 aatttcagtt ttaatatgtt ggctattgaa aatggtgtgc ctaaaatatt gtcactcaga
    29581 caaatcattg ataattacat tagtcatcaa aaagaagtta ttatacgtcg cacccaattt
    29641 gataaagata aagctgaagc cagagctcat attttagaag gcttactgat tgcccttgat
    29701 catttagacg aagtgattgc tattattcgt aacagcgaga cagatgtcat tgctcagaca
    29761 gaattgatgt cacgtttcga cttgtctgaa cgccaaagcc aagctatttt ggatatgcgt
    29821 ttgcgtcgtt tgactggttt ggaacgtgat aagattcaat cagaatatga tgatttgttg
    29881 gccttgattg ctgacttatc tgatacttta gccaaaccag aacgtattat cactatcatc
    29941 aaagaagaaa tggatgagat caagcgtaaa tacgctaacc cacgccgtac agaattaatg
    30001 gtcggtgaag tcctttctct agaagatgaa gacctaattg aagaagaaga tgttttgatt
    30061 accttgtcaa ataaaggtta tatcaagcgt cttgctcaag atgaatttcg tgcccagaag
    30121 cgtggtggac gtggcgtcca aggaactggg gtcaacaatg acgactttgt acgtgaattg
    30181 gtatcaacaa gtacccatga tactttgctc ttctttacga attttgggcg tgtctatcgg
    30241 ttgaaagctt acgaaattcc agaatatggt cgtacagcaa aaggtcttcc aattgttaat
    30301 ctattgaaat tagaagatgg tgaaaccatt caaactatta tcaacgcacg taaggaagaa
    30361 acagcaggta aatccttctt ctttacaacg aaacaaggca ttgtcaaacg tacagaagtt
    30421 tcagaattta ataatatccg tcaaaacggt ctccgtgctc ttaagttgaa agagggagat
    30481 cagctgatta acgtcctttt gacaagcggt caggatgaca ttatcattgg aactcattcc
    30541 ggatattctg ttcgttttaa tgaagcaagc atccgcaaca tgggccgatc agctacgggt
    30601 gttcgcgggg ttaagcttcg tgaagatgat cgcgttgttg gcgcgtcacg tattcaagat
    30661 aaccaagaag ttcttgtaat taccgaaaat ggctttggta agagaacaag tgctacagac
    30721 tatcctacaa aaggtagggg gggaaaagga ataaaaacag ctaatattac ccctaaaaat
    30781 ggtcaattag ctggattggt taccgtagat ggtacagaag atatcatggt gattacaaat
    30841 aaaggtgtca ttattcgcac aaatgttgca aatatttcgc aaacaggtcg tgctactttg
    30901 ggtgttaaaa ttatgaaact agatgctgat gctaagattg taacatttac cttggttcag
    30961 cctgaagaca gtagtatcga tgaaatcaat actgatcgtg aaaatagtat ttcaaaaaat
    31021 aaagataatt aatcataaca aggagtaaaa aatggtaaaa aaacaaaagc gtcgaaaaat
    31081 aaaatccatg tcttgggcaa gaaaactact aatagttgta cttttaattc taggtttagc
    31141 attgcttttt aacaaaccta tccgaaatac attaattgct cgaaactcta ataaatatca
    31201 agtaacgaaa gtttcgaaaa aacaaatcaa aaagaataaa gaggctaagt caacatttga
    31261 tttccaagcc gtagagccag ttagtacaga gagtgtcttg caagcacaaa tggcggctca
    31321 gcaacttcct gttatagggg gcattgccat accagagctt ggcattaatt taccaatttt
    31381 taaaggttta ggaaatactg agcttattta tggcgcagga acgatgaaag aagaacaagt
    31441 tatgggagga gaaaataatt attctcttgc cagtcatcat atttttggaa ttacaggttc
    31501 atctcaaatg ctcttttcgc cgcttgaaaa agcacaaaat gggatgtcca tctatttaac
    31561 agataaagaa aaaatttacg aatacatcat aaaagatgtt ttcacggtag ctcctgaacg
    31621 cgttgatgtt atcgatgata cagctggtct caaagaagtg actttagtga cttgtacaga
    31681 tatcgaagca acagaacgta ttattgtcaa aggagaacta aaaacagaat acgattttga
    31741 taaagcgccc gccgatgtat tgaaagcttt taatcattct tataaccaag tatctaccta
    31801 gatatatctt aaatataata tttaaaaagt aggaccatag agaaaattta tctcatccta
    31861 ctttttttga aaggagaaat atgatgaaac taaatgccat tcatcacgtt gctattattg
    31921 tatctgatta tcatctgtca aaagattttt atgtgaataa actcggattt gaaattatca
    31981 gagaaaatta tcgtcctgac aagcatgatt acaaattaga tttatcttgt ggtcgtattg
    32041 aattggagat ttttggtaag gtgacaagtg acccctacta tcaagctcct cctaaacgtg
    32101 taagtcaacc agaatttaaa agtgaggcct gtggtttgag acaccttgct tttcgtgtta
    32161 ccaacattga gagttatgta gatgatctaa agagcttagg aattccagtg gagcctatta
    32221 ggcatgatga ttacacaggt gagaaaatga ctttcttttt tgatccggat ggtttgcctt
    32281 tagaattaca tgaatagact tattaggtta acgactggat cgtgctatta aactcgttaa
    32341 aaatagttat ttgttgtatc ttcttttgct tgattaatct cttttgatcg ttaaatgatt
    32401 tggttaactt tcaaagtgaa gagcaatttt tggagtaatc ttgtcgaagt tttttaatag
    32461 aataactata ggaaaagcaa aatatttgac gataaactct tacagtgtta taatgacaat
    32521 ataagtaaat aactgtgttg tcactttgtt gaaatgtttt cgtattaatg tttttttatc
    32581 tattacgata gataatttta cttcaatttt tgattgaaaa tactaaaata agtgatgtgg
    32641 tcactttgac aaccatttat tggtcctttt agataagaca attttgtggc tcttcagttg
    32701 aaaggatgtg ttgttgatgt tagaggaaac aatcatgtta aattaactca ggcttaaaga
    32761 ccaaaaaagg agtgaagtct attatgaaaa aaagaaattt taaacttaca gaaatgttac
    32821 aattggtttt attagtggtt cctgctgtaa aacttgctaa aaaaattttt aacgatagta
    32881 aaacaccgtc taaaagaaag taggtctaca atgactaaaa aaaatcatgg cgttttttgg
    32941 gggttgttgc ttggatcagc agcagctagc attgcttact taagtttatc gtcttccaaa
    33001 aaagatcaac tcttgaaaga tagtgctaaa aaaatagatg atctcaacgc ttacttgcaa
    33061 gataaaagta agcaagttct ggatgcagta tcggaaaaag tacaagaatc caaagatgct
    33121 gttgaagttt atggtggtat tgccgcagaa accgttgaag aaaagtggca agataccaaa
    33181 gatgctgttg aagtttacgg tggtattgcc gcagaaacag ttgaagaatc tttgggacag
    33241 gctaaagaaa aggtagaagg aattggcgaa gctactagtc aaactatcca atctaaaatg
    33301 gaaaaactca ccagcgataa gacagatgct gatgatgatg atgaaaaata ggttttaaaa
    33361 tacctttaag ataagacaaa aagtgccatt aggcactttt ttaatcttct gttggaacaa
    33421 taatcgaaat ggcttttgga atgatatcta attgaatggg cagatagtca cttttatccc
    33481 catcaatcct ggtacgtggt aatatcgctt gttttttagc ttgtggtagt aagctaagcg
    33541 tattggcttg aaaatgactg atttcctctg ctttggaaaa atcaccctgt ttaaaatcat
    33601 taatatgcca taaaaattta aagaaagaga cttttttcat ggtataaact tggaaatagc
    33661 catcgtcagc ttgagcacca ggagaaaaag aaggaaaacc agcaatggta tttgtcatcg
    33721 tgattaagag aaacttcgtt tttaggtgaa tacgatggtt gtggctaatt aaagagatgg
    33781 catagctgcg atttcttttc agtattcgaa tactatcttt taaaaatgct agaggaccaa
    33841 agcgtcgttt ttcctcagcc gttacgtcgg cagcaatatc agccagtaat cctaaggtta
    33901 aactggaaat catgtattgc tggttagctt tgcaaatatc aacttgtttg atttgtcccg
    33961 tcaagatagt atccaacgcc tcagtaattt gtaaagggat atgcatagcc ttggcaaaat
    34021 tattgactgt ccctgagggc actaagccta ttaaacaatg agctcctcct tcatagatgc
    34081 caccgatgat tttatttagt gtcccatcgc caccaagagg gataaccaag tcaatcttgt
    34141 ccttagcagc ttgttttgct aattgaaaag cctggtcagc atctttaggg gtaataactt
    34201 ctacagaatc ttcggaaaaa ccatgttggc aaaaatagtc tttgacttgc ccagcaagtt
    34261 ggtcttcttt ctttccagaa ttaggattgt aaaaaatccg aacggttttc atcaggtctc
    34321 tcctttgaca gcttattact tgctatccat tataccactt ctaagaattg atgtcttaca
    34381 ccaactcatc acattaagcc tctcaatcag tctgagcatc tatttatctt aaagcataaa
    34441 gaaagtgata gcgataaatt ggagggcaga ggccaataaa ataaagagat gccaaatcat
    34501 gtggaagtag ggtctttttt tggcataaaa taccgctcca atggtataag acaagccacc
    34561 aaataacatg agaagaccaa aagcaagact agttttttga atgatgactg gcaagataaa
    34621 cacaacgagc cagcccataa cgatataaag catcaaactg aatttttcat tgatacgttt
    34681 agcaaaaatt ttgtataaaa tcccaaaaag cgtaatgccc cactgcaaaa caataatgat
    34741 atagcctagc caaccagaaa caagggataa ggcaacaggt gtataacttc ctgcgatagc
    34801 aatgtaaatc atactgtgat caataatgcg tagaatgtat ttgtgaaccg aaccataagc
    34861 catggagtgg taaatcgtag aggacaaaaa catcaaaaag agactgatga caaagatgga
    34921 gataccaata gcggctttaa ggtcataagt ttgataagca tagctggctg aaataggaag
    34981 tagaatgagc atagcaaatg ctccgatagc gtgtgtcacg ctgtttgcta cttcctcact
    35041 aaaagataag ggtaaacttt gtttaaaggt ttggttcatt gggtcacctc ctgtaataaa
    35101 taaatagttt tgtggtaatc tttgaccgtt tgacaggcaa cctgcacaat cggtggaatg
    35161 tcctcctcaa tgggagcctt ctgattccaa caggttacaa aagtattgta aagactttca
    35221 gaatcagcct gtgcctgaag ttcctccaat acgcgactaa tatcttgaat aggaaatacc
    35281 gttttaaaca aactgatggc aattaagcgc gctagttgtt gcttttggta ttttttcttg
    35341 ataggtttag tcacataccc atgcttgacg taattattaa tcatagatgc cgttagtgat
    35401 ttattatctg acacttctga aaaatcagtg cactggttga cataaagtaa gacttgatcc
    35461 aaatataagt ctaaatcagg gaggtccttc caataaggta atgatggaaa aatcatagtt
    35521 tcgtctctct atctagtttt gataactaga ttatatgatt aatgaaaact tattgcaagc
    35581 aaaaactgta aagacttaaa agaggaaagt agaaatggcg aagtgaagct aatcatgcta
    35641 taatgttaaa gaattgattg ggatagatgc cttctgtcgc aatcagacta ttttatcacg
    35701 aagaagatga tgctacgaaa ggaatttaaa ctctatggct actattcaat ggtttcctgg
    35761 gcacatgtcc aaagccagaa gacaggttca ggaaaatgta aagcatgttg actttgtaac
    35821 tattttagtg gatgcacgct taccactttc tagtcaaaat cccatgctta caaaaattgt
    35881 tggtgataaa cctaaattaa tgattttaaa taaagctgac ttggcagatg caactcgaac
    35941 taaagagtgg aaggcttatt atgaaagtca aggtattaaa acattagcca tcaattccaa
    36001 agaacaatca acggttaaaa aagtaacaga agcagccaag gaactcatgg ctgataaaat
    36061 tcaacgcttg cgagagcggg gcattcaaaa agaaaccttg cgaaccatga ttattggcat
    36121 tccaaatgct ggtaaatcta ccttaatgaa tcgcttggct ggtaagaaaa ttgctgtagt
    36181 tggcaataaa cctggtgtga ctaaaggaca acaatggttg aagtccaata aggaattgga
    36241 aattctagac actcctggta ttttatggcc aaaatttgag gacgaattgg tgggcttaaa
    36301 attagcttta acaggtgcta tcaaggacca attactacca atggatgagg tcactatttt
    36361 tggtttgaat tactttaaaa cacattatcc tagtcgcctt actaagcgtt ttaagaatat
    36421 tcctcttgag gaagaagctc ctgaaatcat tatgaccttg acacgccaac tgggatttaa
    36481 agatgattac gaccgtttct acactttatt cgtcaaggaa gttcgtgatg gtaaattagg
    36541 tcaatacacc ttagatcagg tgggagatat ggatgtcgac tagtattaaa gctattaaag
    36601 aaagcctgga agctgttact agcctcttgg accccctctt tcaagaattg gcaaccgaca
    36661 ctaggtcagg cgtccaaaaa gctctaaaaa gccgacaaaa ggctattcag gccgagttag
    36721 cagaagaaga acgattagaa gccatgcttt cttatgaaaa agctctttat aaaaaaggtt
    36781 atcaagccat tgcaggtatt gatgaggtgg gacgtggtcc cttagcaggt cccgttgtgg
    36841 cagcttgtgt gattttacct aagtattgta aaattaaagg ccttaatgat tctaaaaaaa
    36901 tccctaaatc taagcatgag accatttatc aggcagtgaa agaaaaggct ttggctatcg
    36961 gtatcggtat tattgacaat cagcttattg atgaggtcaa tatttatgaa gcaaccaaac
    37021 tagctatgct agaagccatt aaacagttag agagccaact cacacagcca gattatctct
    37081 tgattgatgc catgacattg gatattgcta tttcgcagca gtctattctt aaaggcgatg
    37141 ccaattcctt gtctattgca gcagcatcaa ttgtagctaa ggtcaccaga gatcagatga
    37201 tggctaacta tgatcgcatt tttcctggtt atggcttcgc taaaaatgca ggctatggca
    37261 ccaaagaaca tttacaggga ttaaaagctt acggcataac gcctatccat cgtaaaagtt
    37321 ttgaacctgt taaatccatg tgctgcgatt caactaatcc ttaaaaagtt ctgtttttag
    37381 cagaattttt ttctttttta cgaataaatg aagtaaggag gtaacttagt gaatcatttt
    37441 gaactttata agctaaagaa agctggactg actaataaaa acattctcaa tattcttgac
    37501 taccaagaac accaggaaaa atcgttgtca cttcgagata tggccgttgt ttctggttgt
    37561 aagcatccgt ctcactttat agaagcctat aagcagttag atattcaaaa tttaaaaata
    37621 gaatttaaac agtttcctag tatttctatc ttagataagc attacccaat ggcattgaaa
    37681 gaaatataca atccacctgt cctcttgttt tttcagggaa atttagacct tcttgagaaa
    37741 cctaaattag ccattgtcgg ctccagacgc tcaagcgata ccggagtaaa gtctgtccgt
    37801 aaaattctta aagaactcgg gaaccgtttt gtgattgtta gcggacttgc tcgaggtatc
    37861 gacactagtg ctcatttagc ctgccttaaa aatgggggac aaaccatcgc tattattgga
    37921 acagggttgg atcgctttta ccctaaagaa aatagggagt tgcaaacttt cttagggaaa
    37981 aatcatcttg tgctaacaga atacggtcca ggagaagaag ctttatctta tcactttcca
    38041 gaacggaatc gtattatcgc aggccttagc cgaggtattc ttgtcgttga agcaaaaaat
    38101 cgttcaggtt ccttgattac ttgtcaaatt gggatagaag aaggccgaga catttttgct
    38161 gtcccaggaa acattttgga cgggaaatcc gaaggttgcc ttcagttaat taaagaggga
    38221 gcaacatgcg tcacgtcggg catggatatc ctttcagagt actaaaaaag ttaaagtttc
    38281 ttcctatgta gcattttttt attgacagtt tcttaaaaat gggatattat gctataagct
    38341 ttaaacaaac tgttatagga agtgtgtcga attgggaaca aaaactacaa ctaagccaaa
    38401 aacgggtact aaaaagtcca ccactaaaaa gaaatcaata gcgaaaaaaa atctcgttat
    38461 tgttgaatca cctgccaaag ctaagactat tgaaaaatat cttggacgca gttataaagt
    38521 tgttgcttcg gtaggacata ttcgtgactt aaaaaaatcg tctatgtcta ttaattttga
    38581 taataattat gagccacaat acattaatat ccgtggtaag ggacccctta tcaattcttt
    38641 aaaaaaagaa gccaaagctg ctaaaaaagt ttatttagct agtgacccgg atcgtgaggg
    38701 agaggctatt tcttggcatt tgtcacatat cttaggactt gatcctcaag ataataaccg
    38761 agtggttttt aatgaaatta cgaaagatgc agttaaacat gcctttgtgg agcctcgtca
    38821 gattgatatg gacttggtag attctcaaca agcacgtcgt gttttggacc gtattgtggg
    38881 atattccatt tcaccaattc tttggaaaaa ggtcaaaaaa ggactttcag caggacgtgt
    38941 ccagtcggtt gctttaaaac tcatcattga ccgtgaaaat gacatcaaag catttgttcc
    39001 aaaggaatac tggtctattg atggtctttt taaaaaagga actaaaaagt ttcaagcgac
    39061 tttttacggt attaatggca aaaaaacaaa gcttgataat aacaacgatg tcaaagaggt
    39121 attagcaaag ctaacaaatg aagattttct tgtcagcaag gttgacaaga aagagcgacg
    39181 tcgtaatgct cccttacctt acacaacatc atctcttcaa caagatgctg ctaataaaat
    39241 caatttcaga acgcgtaaaa ccatgatggt agcccaacaa ctgtatgagg ggattcattt
    39301 aggagaaaat ggaactcaag gtttaattac ctatatgcgt actgattcta ctcgtatcag
    39361 tccagtagca caaaacgatg ctgctcaatt tattatcaat cgctttggag ctaattattc
    39421 aaaacatggt aatcgtgtca aaaataccag tggtgcccaa gatgctcacg aggcgattcg
    39481 tccatctagt gttaatcata cgccagactc tattgccaaa tacctcaaca aggatcagtt
    39541 aaaactttat acgcttattt ggaatcgttt tgtggctagc caaatgacag cagctgtttt
    39601 tgataccgta aaggtgaact tggagcaaaa tggcgtgatt tttgttgcca atggtagcca
    39661 aatgaagttt gatggttaca tggctgttta caatgattcc gataaaaaca aaatgttacc
    39721 tgaaatggaa gaaggagaaa acgttaaaaa ggtatcaact tctccagaac agcacttcac
    39781 gcaacctccg gctcgctact ccgaagcaac tctgattaaa actttagaag aaaatggggt
    39841 cggtcgacca tcaacttatg ccccaacctt agaagtgatt caacgcaggt actatgttaa
    39901 attatctgct aagcgctttg agccaactga gcttggggaa attgtcaaca agcttattgt
    39961 cgaatttttc ccagatattg ttgatgttgc ctttactgcc gagatggaag gtaagctaga
    40021 tcaagttgaa atcggtgaag aagaatggca acatgtcatc gatcaattct atcaaccctt
    40081 tgtcaaagaa ttgaataagg ctgagtctga aattgaaaag attcaaatca aagatgagcc
    40141 agctggtttt gactgtgatg tttgtggcca cccaatggtc attaagttag gacgttttgg
    40201 gaaattttac gcgtgtagca acttcccaga gtgccgtaat acaaaagcca tcactaaaga
    40261 aattggtgtt acttgtccgg tttgtcataa aggacaagtt atcgagcgta aaaccaaaaa
    40321 aaataggata ttttatggtt gtgatcagta tccagattgt gagtttatct cgtgggattt
    40381 acctattgga cgtgcttgcc ctaagtcagg tgactatctt attgagaaaa aagttcgtgg
    40441 tggcaaacaa gtaatgtgta gcaatgagac ctgtgattac aaggaagaaa aaattaaata
    40501 aaaaaagaat tggaactcct tgtcttgttc caattctttt tttatttaca aaggtatttt
    40561 taactacaaa aatcgctagt tcgtttttaa aaggcttaaa aattcctcaa taactggact
    40621 gaaactcgca tcatctcggt aagcaatccc aatagggtaa aaattatttt tatcttgcaa
    40681 aggaatccaa actaagttat ctacctgatt aagactctca aaatcactcg ggaggatagt
    40741 caaggtattt aaatcgtgca aactatgaat aagaacttcc caatcattgt gtttaaagac
    40801 aatatctggt tcaaaaccga gagctcggca ttttctagga agcatttcgc ctaacatgta
    40861 gtgatcgttt aaagaagcaa tcttatagcc ttttaaatct ttaagtttta actgaggatg
    40921 ttgcgccaaa gggtgctgtt tgaggagaac gatactgacc ttatagcctt ttgtggacgt
    40981 ttgtaatagc tcaatggtaa tatccttttg aatacttaga aaggagagga gaccaatatc
    41041 gatttttcct tgggacaata attcttataa tttgcgagaa ccatcctgta taagtgatac
    41101 ttcaacattt gagtgagtag ccataaagat tgaaatttgt ttcatgaatt gtatagcaaa
    41161 cagtgatgtt aattcaacac gaatcatctc tttttttctt gatttaattg ctgaatatcc
    41221 gcaacaattt gattaaagtc atccacaagg tctttgcctt tgtgataaag aatatctcca
    41281 gcttcggtta gtagtagctg tcaatcactt tgtgtaaaaa gcgtggtgtt caaactagga
    41341 ctctagcctt ttaattgatt gagaaagagt atgttgcgtt acaaacaaac ttttagcagc
    41401 gtgggaatga ttttttgttt cagcaactgc aataaaatag gttaattatc taatatccat
    41461 agtagatcct tcatgattag tcagggaatt gcgtctctac ttggtttaca acctattttg
    41521 atgtctctcc ttattgccat gattttctgc ttccttattg tttctccaat tacaacggta
    41581 ggaattgctc ttgcgattaa cttatctggt attggttcag gtgctgcaaa cttaggtatt
    41641 tgtgccgcaa gctttggact ttgtttagca ggttgggctg ttaattcaaa aggaacttca
    41701 cttgctcacg tcttgggatc accgaaaatt tcaatggcca acgttttatc aaaaccaaaa
    41761 atcatgttgc caatgttatg ttctgcagct gtacttggtg ttattggtgc tatctttaat
    41821 attcaaggaa cacctgctag tgcaggcttt gggattagtt gtttgatcgg acctatcaat
    41881 gcccttaatt tagctaaagg cggatggtct ctagtaaata tcctacttat cattatcatt
    41941 tttgtaaggg caccaattgt tctcaatatg atctttaact acctttttat caaggtgctt
    42001 aaagtgattg atccaatgga ttacaaactt gatatctaag aaaggaactt ttgatgaaat
    42061 taaaattata taatgttaga ggcgaagaag cagtcttagc aaaaaaatgg gctgatgaca
    42121 atgggattga gatttccttg acagagtctt ccttaactcc tgaaacggtt aaagaagctg
    42181 aaggctttga cgggattgcc aatgcccaaa ttggtccttt agatgatgca atctatcctc
    42241 tcttaaagga aatggggatt aaacaaatcg ctcagcgcag tgctggtgtc gatatgtata
    42301 accttgattt ggccaccgaa aatgacatta ttatcacaaa tgttcctagc tattctccag
    42361 aatccattgc agaatttacg gttactattg cccttaattt aattcgtcat gtggagttga
    42421 ttcgtgaaaa tgttaaaaaa caaaatttca cttggagact ccctatccgc ggccgtgttt
    42481 taggtgatat gacagttgcg attatcggaa ctggccgtat tggtctagct actgctaaaa
    42541 tctttaaagg ttttggctgc aaggtcgttg gatatgatat ttaccaaagc gatgctgcca
    42601 aagctgtctt ggactataag gaatctgtag aagaagcgat taaagatgct gatcttgttt
    42661 ccttacacat gccaccaact gcagagaaca cacacctttt caatgctgat ttatttaaat
    42721 cattcaaaaa aggggctatt ttgatgaata tggcgcgtgg tgctctcatt gagacgcaag
    42781 atttactgga tgctttggat gcaggcttat tgagcggagc tggtattgac acttacgaat
    42841 ttgaaggacc ttatattcct aagaattttg aaggtcaaga aattacagat tcactattta
    42901 aagctttgat taaccatcct aaggttattt atacgcctca tgcagcttat tatactgatg
    42961 aagccgttaa aaacctagtt gaaggtgccc ttaatgctac agtagagatt atcaaaactg
    43021 ggacaacgac aactcgtgtt aactaacaac tgatttgacg tccattataa aggaataatt
    43081 ccaaaaattc ctttataatg gacttttttg tattagtccg ttataataga ctgtaagaaa
    43141 gggggctctt atgacatata tagcgcttat tggagatatt atccagtcca aacaattgac
    43201 ggatcgttcc aaagttcaaa aaactttagc agcttattta gacgacctca acaaaacctt
    43261 tgctccttat attatttcta aattatccct aacgttggga gatgaatttc aaggactttt
    43321 tcaggtggat actcctattt tccatctgat tgatttgatt aatcatcaca tggatatccc
    43381 tattcgattt ggagtaggag taggttctat tctaacagac atcaatcctg atattagtat
    43441 tggggctgat ggacctgctt attggcatgc tcgtgaggct attcgttata ttcatcaaaa
    43501 aaatgattat ggtaatacta cattagctct tcggactggt catcacaacc aggatgatgt
    43561 attaaacagt ttactagcag ctggagatgc tattaaagcc aactggcgag ctagtcaatg
    43621 ggaaattttt gacacgcttt tagatttggg catttatgag gaatactttg atcaacaacg
    43681 actaggaaag caattatctc ttagctctag cgctttgtca aaacgtctaa aaagtagtca
    43741 tgttaaaatt tatctgagaa cacggcagag tgcgctaaac tgtctcaaac aaatcaagga
    43801 ggaaactgat gattaatggt gtctctcact acctagctca aacccctaca cttaccctgt
    43861 ttctcatttg tcatgtgtta tcagactacc agttacaaag tcagcaagta gctgatttaa
    43921 aagaaaaaca tttgacttat ttaggttacc acttgattgg agttagcatt cccctaattt
    43981 gtttaaccct cattatccca caagcatggt tgatgagcct attggttatg ataagtcacg
    44041 cgcttattga ctggctaaag ccaaagatgg ctaactctct aaaatggaaa agagagtgga
    44101 tttttctgct ggatcaatgc ttacatatcg ctattagttc atttgctggg ctaaggttag
    44161 caggggtgac cttgcctaat tggcttccga tatctatttt gatgaccgtt ttatttatcc
    44221 tagtcattac caaaccaact aatattgtct ttaaactctt tttcagcaaa taccagcctg
    44281 accaaggaga aaaaatggac acgatcatag gagcgggggc taccatagga attctagaga
    44341 gaattgttat tggtttgtgt atgatcatgg ggcaatttgc ttcaataggt ctggtcttta
    44401 ccgctaaatc tattgctcgc tacaataaaa tttcggaaag tccagctttt gcagaatact
    44461 acctgattgg gtctttattt agtattctca gtgtttttat cgcagcatgg atttgtttct
    44521 tctagttgaa aagggttccc gtagaaagag gttatcgctt agtctctttc tctttctctt
    44581 tctttttctt tcttcttatt tctgttataa taagtcaggt aactacatta gaaagatttg
    44641 tgggtctgtc atctaagaga tgtcattccc gaagaggtat tagtgacttg tctcaatcaa
    44701 ctgcaactta tattaatgtt attggagctg ggctagctgg ttctgaagct gcctatcaga
    44761 ttgctaagcg cggtatcccc gttaaattgt atgaaatgcg tggtgtcaaa gcaacaccgc
    44821 aacataaaac cactaatttt gccgaattgg tctgttccaa ctcatttcgt ggtgatagct
    44881 taaccaatgc agtcggtctt ctcaaagaag aaatgcgtcg cttggattcc attattatgc
    44941 gtaatggtga agctaatcgt gtacctgctg gaggagcaat ggctgttgac cgtgaggggt
    45001 atgcagagag tgtcactgca gagttggaaa atcatcctct cattgatgtc attcgtgatg
    45061 aaatcacaga aatccctgac gatgccatta cggttatcgc gacgggaccg ctgacttcgg
    45121 atgccctggc agaaaaaatt cacgcggtaa atggtggcga tggattctat ttctacgacg
    45181 cagcagcgcc tatcattgat aaatctacta ttgatatgag caaggtttac ctcaaatctc
    45241 gctacgataa aggcgaagct gcttacctca actgccctat gaccaaagaa gaattcatgg
    45301 ctttccatga agctctgaca accgcagaag aagccccgct gaattctttt gaaaaagaaa
    45361 agtattttga aggctgtatg ccgattgaag ttatggctaa acgtggcatt aaaaccatgc
    45421 tttatggacc tatgaaaccc gttggattgg aatatccaga tgactataca ggtcctcgcg
    45481 atggagaatt taaaacgcca tatgccgtcg tgcaattgcg tcaagataat gcagctggaa
    45541 gcctttataa tatcgttggt ttccaaaccc atctcaaatg gggtgagcaa aagcgtgttt
    45601 tccaaatgat tccagggctt gaaaatgctg agtttgtccg ctacggcgtc atgcaccgca
    45661 attcctatat ggattcacca aatcttttaa ccgaaacctt ccaatctcgt aacaatccaa
    45721 accttttctt tgcaggtcag atgactggag ttgaaggtta tgtcgaatca gctgcttcag
    45781 gtttagtagc aggaatcaat gctgctcgtt tgttcaaaag agaagaagcg cttgtttttc
    45841 ctcagacaac agctattggg agtttgcctc attatgtgac tcatgccgac agtaagcatt
    45901 tccaaccaat gaacgtcaac tttggcatca tcaaagagtt agaaggccca cgcattcgtg
    45961 acaaaaaaga acgttatgaa gctattgcta gtcgtgcttt ggcagattta gacacctgtt
    46021 tagcgtcgct ttaacactaa aaaagagttc cttttcagtt gagttgctga agaggacttt
    46081 tttacttgct gatttgagcg ctagctatgc aaaagaatgc acaaaaaata catgaataga
    46141 ctatggtcac tagaagcaat attatataat gaatagtact cattagttga ttcagtttgg
    46201 aggttttagc atgcagcagc aagtcgcaat aacagaaaca gttttacggg acggtcatca
    46261 aagtttgatg gcaacgcgtt tatctattga ggatatgctt cctgtcctta ccatcttaga
    46321 caagattggt tattattccc tagagtgttg gggaggagca acctttgatg cctgtattcg
    46381 ttttttgaac gaagaccctt gggaaagact gcgcacgtta aaaaaaggct tacctaatac
    46441 ccgtttacaa atgttattaa gaggccaaaa ccttttaggc taccgtcatt atgcagatga
    46501 catcgttgac aaattcatta gtttatcagc tcaaaatggg attgatgttt tccgcatttt
    46561 tgatgcccta aatgacccac gaaatatcca gcaagcctta agagctgtga aaaagacggg
    46621 taaagaggct caactgtgta ttgcctatac aactagccca gtgcacacgc ttaactatta
    46681 cctttcttta gtgaaagaat tggttgagat gggagctgat tctatctgca tcaaagatat
    46741 ggctggtatt ctaactccca aagcggctaa agagttagta tctggtatca aagccatgac
    46801 taacttacct cttattgtgc atacccatgc taccagtggt atttcagaaa tgacttactt
    46861 aaaagtagca gaagcaggag ctgatattat tgatacggcg atttcctctt tttcaggggg
    46921 aaccagtcag cctgccacag aatcaatggc gattgccttg acggatttag gctttgacac
    46981 aggcttggat atgcaagagg tagccaaagt tgcagaatat ttcaatacca ttcgtgacca
    47041 ttaccgagag acagggattt taaatcccaa agtcaaagac actgagccaa aaacattgat
    47101 ttaccaagtt ccaggtggta tgctatcaaa cctattgagc caattagccg agcaaggcct
    47161 agctgataaa tacgaagaag tcttagcaga agtacctaaa gtaagggctg atcttgggta
    47221 tccgccactc gtaacgccat tatcacaaat ggttggcaca caggccttga tgaatatcat
    47281 ctcaggggaa cgctacaagg tagttccaaa tgaaattaaa gactatgttc gagggctata
    47341 cggtcaatca ccagcgccat tagcagaagg tatcaaagag aaaatcattg gtgacgaagc
    47401 agtcattgct tgcagaccag ccgacctaat cgagcctcaa atgatttatc tacgtgacga
    47461 gattgctcca tacgctcgtt cagaagaaga cgtgttaagc tatgcgagtt tcccacagca
    47521 aaccagagat ttcttgggac gccgtgaaga tcctttctat gatgttccgg ttcaagaagt
    47581 tactgtacaa ctggacattc aagactaaca gggaatgact aatcctctta accattaatc
    47641 tccttggtga cacgcatttg ctgtaagaac aataccaaaa acctacctga ttttgataat
    47701 cagataggtt tttttatctt agtaatgttt gacagatgaa gtggcttgta tctttttaat
    47761 aatgggttgg gcttctagcg aacaaaaata atctaaagaa gttttgggaa ggagttttgc
    47821 cagaaggtcc caatcattat ctttcaatgc ctgcctagcc gttgaggcac tgataggatc
    47881 ttgctgctga ttgatagctt tccttggcaa aatatctagg aggataccag cttgctgcaa
    47941 ctgctctgcc atgatttcat tgtaaatagc agttactcgg ctggttggct cttctccaac
    48001 gtatcttttt gtaatctgta aggtttgagc aatctttaga aaaatagcag tatccagcaa
    48061 agcttggctt ttgatcacat cattgtcttc cgtttggaaa taagctggaa aggttgcctg
    48121 actaatcaaa taaggacctg tttcatgaaa gataatgtta tcaagatgtc tcaatccttc
    48181 ttgaatcaac atttttcgta ctgaaaaagg aaccaagctt tggtcctcac taaccataaa
    48241 cagatgaacc caatcatttt ctcttgcagc tttctctact aaaaattgat gccctaaggt
    48301 aaaggggtta gcgttgataa caatagcagc gactttacca ggtgtttgct caggcttatt
    48361 aagtgtcatc agataatctt gaaaaccagt ttttttattt tccaagaaac tgatgtgatt
    48421 gtcgatatgg acaatttcag taaaaccaag atctttgaaa aaagcagcag aagaggtctt
    48481 cgtataaaca aaaagatgat agttgccaag ggcatattct tcatcaatga gatgactcac
    48541 aatcctatta agaagtcctt caccttgata ggcactggat acgcaaagac agcgcaagct
    48601 atttccaaag taagaaccgg tagcaatcac atcattttgc gcattcatga tggcacaagt
    48661 ataatctaaa tgagcatcca aacgaatacc ttcttgatga agcaggttct ttacactagc
    48721 cattgtcgtt ttatctgaag gaaagacttt tgaaacagtg tagtaaggca tttcttctcc
    48781 ttatctttaa ttttattgaa tcataacata acttagtacc aaaacaggct gatctatcta
    48841 aaggcaactc tgttttttat caacgccatt ttttaaaagg aaatcgaatg tgtttgacag
    48901 actcaaaagt atcagcgatt ttttgattgc gttccacagt ccgcaagttt tcttggtcta
    48961 ataagtcttg acttttttcc aaaacatcaa cagtaatgta gtagagtttg atcaggcttc
    49021 ctatcttata tttaccagat tttggagaca tagcaaccac ttcattgaga ttactatgaa
    49081 gccatttttt atgaggctta gcaggtatag tggctactac aaagccaagt tgttccaaat
    49141 gagcttgtgc ctgatcaaca ggaagattaa tcacatcatc tatcgtgcgt agttgcatct
    49201 ctttttcatg tttttgttcc atacgttttt cgataattgg tcgactgtta tcaatcgttt
    49261 ttccaataat ttcagtagtg tcaggaacaa ttgacatcag tttcccaact actcctagag
    49321 cttttcttat tctctttggc atcttttatc tcctcaagtc gtttcttttt attataacaa
    49381 attgtctaaa aatagtatgc gataaacctt gttctaaaag attaaataga tcaattcaag
    49441 gaaaaaatag gaggggatcc gacaaaaaat acaaagattc taaaaaagtc aagctatttt
    49501 agcctttgtc aatcgtatca gttcaaatag aaaatacaag ttttgacaag aatttattta
    49561 tgtaacaaac tttgtttttg attcttcaga ctatctagcg ataatgttat ctgattcttg
    49621 ttttcaacca attgatgtta aagaagctgt cttcatgatt ctctaacatt ccttcagttt
    49681 tagctttata ttactctaag ttatcagtaa tgacattaag tagtttaata agaataatcc
    49741 taaaagctac tttacaaaat aacgtattat catactaaat aaaagtaccg acatactaaa
    49801 aacaggctta tctcatcttt ttgatgagaa ccttactaga tttaatctat aaacatcaca
    49861 aaaaagtcat tcaaagaagg gacaaagtta gcagtgatat tcctttttct aagtggcttg
    49921 agtagtttgg aaaacggcct aacaccaaac tgtcacggtt aatagtagcc atctattaaa
    49981 cttaattttg aagctatttt tacctttaat gttacataaa aacaattatg taacattaaa
    50041 ggttatctaa agcatttttt tgctcatcat tgacaatatg ggtataaaga tccgtgactt
    50101 gagtagagga atggcctaat tgatgactaa ctaacacctg agatttagta gcatcatata
    50161 gtcttgtcgc tagcgtatga cgcaatttgt gaggagtcac acgaatttta aaatcctcag
    50221 agtacttgcc aaccatcttt tctatactag aagcatccat tcgatttgga acgccacggt
    50281 attctgttaa aaagaaagca agatcctgtt tttcagcctt gtaacgtctc tgacgaacag
    50341 ctaaataaga ctccaaataa cctttcgcaa aacctgctac attgactgaa tcacgttttc
    50401 cgcctttgcg aataacttcg ataatcatca tatttagatt gacatctttt aaatcaagat
    50461 tcactgcttc agacaaacga acaccagaag caagtagtag agcaataata gccaaatccc
    50521 tctccttatt tttacggaaa gaagatttgg cacgattaga caatttttgc tcatattcct
    50581 tatccacata atccaagaaa gctagagttt catcacctaa aaacagtttc tgcttaatat
    50641 tttccgctct ggaagccagg gtttcttttt tcttttttgt tgacactttt ttcataacat
    50701 tccgataaaa ataaggctcc ccttggtcat tttcaacctc ttcagtcaag tacttgtaaa
    50761 ggcttgatag ggcagacaag gtccgattaa tagtggtttg agaaagcccc tctttggtgg
    50821 aataggtgtt gagagaaggt cgttcccgca aataaagcac aaaggcctct aaatccttct
    50881 tggtaaggtg ctcaagcgtg ctcaagtcaa tatcagcaat ctttggcgcc tgcgttaaat
    50941 cagcatccat cagccaatca aaaaagcgtt tgtattcttt taaatactca tataaggtgg
    51001 taaagctgta tggaacagct aacttggatt ggtaataatc taaaacatac caaggcatga
    51061 tggccttata ggtttcaatt ttttctagta ataattcgcg tctcatatca tcataattcc
    51121 ttaacaataa caattttttc aaaaatgaat tttcgcaaat tgtctcatgt attttatgtc
    51181 attcattctc tacaagagca gtatatcaca cctataaata tttttcaaga aaattacagt
    51241 ttttcggaaa gatgtcacga gacaaatctc tttttttaca
//
LOCUS       DAUGUF010000011        48638 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUGUF010000011 DAUGUF010000000
VERSION     DAUGUF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48638
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.011"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            269..3001
                     /locus_tag="VIB71_000625"
     CDS             269..3001
                     /locus_tag="VIB71_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEQ8822377.1"
                     /translation="MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPEKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKVGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      3166..3281
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            3279..3779
                     /locus_tag="VIB71_000626"
     CDS             3279..3779
                     /locus_tag="VIB71_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEQ8822378.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            3973..5931
                     /gene="ligA"
                     /locus_tag="VIB71_000627"
     CDS             3973..5931
                     /gene="ligA"
                     /locus_tag="VIB71_000627"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEQ8822379.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELAGLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKENFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            5945..6967
                     /locus_tag="VIB71_000628"
     CDS             5945..6967
                     /locus_tag="VIB71_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ8822380.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            7359..7556
                     /locus_tag="VIB71_000629"
     CDS             7359..7556
                     /locus_tag="VIB71_000629"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEQ8822381.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            7591..8307
                     /gene="atpB"
                     /locus_tag="VIB71_000630"
     CDS             7591..8307
                     /gene="atpB"
                     /locus_tag="VIB71_000630"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEQ8822382.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            8325..8819
                     /gene="atpF"
                     /locus_tag="VIB71_000631"
     CDS             8325..8819
                     /gene="atpF"
                     /locus_tag="VIB71_000631"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEQ8822383.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            8819..9355
                     /locus_tag="VIB71_000632"
     CDS             8819..9355
                     /locus_tag="VIB71_000632"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEQ8822384.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            9371..10879
                     /locus_tag="VIB71_000633"
     CDS             9371..10879
                     /locus_tag="VIB71_000633"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEQ8822385.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            10895..11770
                     /locus_tag="VIB71_000634"
     CDS             10895..11770
                     /locus_tag="VIB71_000634"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEQ8822386.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            11932..13338
                     /gene="atpD"
                     /locus_tag="VIB71_000635"
     CDS             11932..13338
                     /gene="atpD"
                     /locus_tag="VIB71_000635"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEQ8822387.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            13351..13767
                     /locus_tag="VIB71_000636"
     CDS             13351..13767
                     /locus_tag="VIB71_000636"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEQ8822388.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            14033..14290
                     /locus_tag="VIB71_000637"
     CDS             14033..14290
                     /locus_tag="VIB71_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEQ8822389.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFC"
     gene            14355..15626
                     /gene="murA"
                     /locus_tag="VIB71_000638"
     CDS             14355..15626
                     /gene="murA"
                     /locus_tag="VIB71_000638"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8822390.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            15630..15818
                     /locus_tag="VIB71_000639"
     CDS             15630..15818
                     /locus_tag="VIB71_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8822391.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            15854..16393
                     /locus_tag="VIB71_000640"
     CDS             15854..16393
                     /locus_tag="VIB71_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEQ8822392.1"
                     /translation="MLTRKKRKRVQEQKVPKRANALLTKSTRQYQDRSQLKKGYRSFK
                     PAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKP
                     YSTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLKAKSSDDSLAFNVFVP
                     NVQAGLTVDYRTGQIAINL"
     gene            16676..17719
                     /gene="pheS"
                     /locus_tag="VIB71_000641"
     CDS             16676..17719
                     /gene="pheS"
                     /locus_tag="VIB71_000641"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEQ8822393.1"
                     /translation="MDLQAQLEELKSKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            17929..20334
                     /locus_tag="VIB71_000642"
     CDS             17929..20334
                     /locus_tag="VIB71_000642"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEQ8822394.1"
                     /translation="MLVSYKWLKELVDIDVTPVALAEKMSTTGIEVEGIEVPAEGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIELSIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYLGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVAEKPVALAGVMGGQATEIDGNS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTSIKLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            20444..20821
                     /locus_tag="VIB71_000643"
     CDS             20444..20821
                     /locus_tag="VIB71_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEQ8822395.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTVAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            20814..21200
                     /locus_tag="VIB71_000644"
     CDS             20814..21200
                     /locus_tag="VIB71_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEQ8822396.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            21273..22349
                     /locus_tag="VIB71_000645"
     CDS             21273..22349
                     /locus_tag="VIB71_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822397.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVRLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GIGNITIAQAVLLQTFLLSALGSGLGLLGTWLTSLVLPEAVPFQSNWLVYLAILVSMV
                     CFALLGTLFSVFSIVRIDPLKAIG"
     gene            22359..23027
                     /locus_tag="VIB71_000646"
     CDS             22359..23027
                     /locus_tag="VIB71_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822398.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGIAGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYRMQDGEL
                     RQER"
     gene            complement(23131..24048)
                     /locus_tag="VIB71_000647"
     CDS             complement(23131..24048)
                     /locus_tag="VIB71_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEQ8822399.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASTRQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRAVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            24199..27414
                     /gene="rexB"
                     /locus_tag="VIB71_000648"
     CDS             24199..27414
                     /gene="rexB"
                     /locus_tag="VIB71_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEQ8822400.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLIDKLILFLEKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            27375..31043
                     /gene="addA"
                     /locus_tag="VIB71_000649"
     CDS             27375..31043
                     /gene="addA"
                     /locus_tag="VIB71_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEQ8822401.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDITHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKTEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYCFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADVFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            31183..31995
                     /locus_tag="VIB71_000650"
     CDS             31183..31995
                     /locus_tag="VIB71_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8822402.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLEAPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            32136..32312
                     /locus_tag="VIB71_000651"
     CDS             32136..32312
                     /locus_tag="VIB71_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEQ8822403.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(32440..32802)
                     /gene="mscL"
                     /locus_tag="VIB71_000652"
     CDS             complement(32440..32802)
                     /gene="mscL"
                     /locus_tag="VIB71_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEQ8822404.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            32932..34746
                     /gene="dnaG"
                     /locus_tag="VIB71_000653"
     CDS             32932..34746
                     /gene="dnaG"
                     /locus_tag="VIB71_000653"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8822405.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPIPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     EILYQRLKQQGYITSYDLSEMSEEINRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            34755..35864
                     /gene="rpoD"
                     /locus_tag="VIB71_000654"
     CDS             34755..35864
                     /gene="rpoD"
                     /locus_tag="VIB71_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEQ8822406.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            36100..36438
                     /locus_tag="VIB71_000655"
     CDS             36100..36438
                     /locus_tag="VIB71_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEQ8822407.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            36576..37430
                     /gene="rfbD"
                     /locus_tag="VIB71_000656"
     CDS             36576..37430
                     /gene="rfbD"
                     /locus_tag="VIB71_000656"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEQ8822408.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            37549..38703
                     /locus_tag="VIB71_000657"
     CDS             37549..38703
                     /locus_tag="VIB71_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEQ8822409.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEDNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWSK
                     QKGQLAELINQVDAGFDSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            38693..39625
                     /locus_tag="VIB71_000658"
     CDS             38693..39625
                     /locus_tag="VIB71_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8822410.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            39628..40431
                     /locus_tag="VIB71_000659"
     CDS             39628..40431
                     /locus_tag="VIB71_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822411.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYVVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            40431..41636
                     /locus_tag="VIB71_000660"
     CDS             40431..41636
                     /locus_tag="VIB71_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822412.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            41661..42668
                     /locus_tag="VIB71_000661"
     CDS             41661..42668
                     /locus_tag="VIB71_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8822413.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTVYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEMSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            42665..44410
                     /locus_tag="VIB71_000662"
     CDS             42665..44410
                     /locus_tag="VIB71_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEQ8822414.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETNDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            44407..46881
                     /locus_tag="VIB71_000663"
     CDS             44407..46881
                     /locus_tag="VIB71_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ8822415.1"
                     /translation="MIKDTFLKTNWLNISHHITLLVFGFYFSFYSLAKELVSSTAQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVRAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKLSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVAILAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNVQYDVTIGKGYLLKHKTFFKISR"
     gene            47060..47755
                     /locus_tag="VIB71_000664"
     CDS             47060..47755
                     /locus_tag="VIB71_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8822416.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDASDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            47757..48098
                     /locus_tag="VIB71_000665"
     CDS             47757..48098
                     /locus_tag="VIB71_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEQ8822417.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            48091..>48638
                     /locus_tag="VIB71_000666"
     CDS             48091..>48638
                     /locus_tag="VIB71_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ8822418.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVSLVFIM"
BASE COUNT        15559 a         8242 c         9834 g        15003 t
ORIGIN      
        1 atgaaatgtt tttgttacaa taagcatgta tcgaatgcta taaagctgtc ttgttcgcta
       61 tcaggggtgc ttgtgatgtt atgtcagatc aaacaagtct ttaattgggt gacttaacag
      121 attaaaagaa aagatctaat cgtgttactt gatagtataa ttaatgcaaa cagaaagtgt
      181 atcccaattc atagtttcag gtggaggtta atattcaaaa ataaaatctt gttgttgtct
      241 taaactaatc acattaaaag gagatatcat gattaacaag aaatatataa tacctgtttc
      301 attgttgaca ctagctatta cgcttactag tgttgaagaa gttacttcac gccaaaattt
      361 gacttatgcc aatgaaatcg taacacaaag gccaaagaga gaatctgtta ttagtgataa
      421 atcgaatttt cccgtcatat caccttacct agcaagtgtg gattttggtg agagaaaaac
      481 acctttgcca acacctgata aaggagtaaa agtaactact gaacagtcta ttgctcaagt
      541 aagaaagggg cctgaagaaa gaacctatac tgttactggc aagattacga gtgtgatcaa
      601 tggctgggga ggctatggct tttatattca agatagtgaa ggtattggac tttatgttta
      661 tcctgaaaaa gatttaggat acagtaaggg agatattgtt caattaacag gtacacttac
      721 tcgctttaaa ggtgatttac aactccaaca ggtgactgca cacaaaaagt tagagttatc
      781 ttttccgact tctgttaaag aagcagtaat atcagaatta gaaacaacaa caccctcaac
      841 attagttaag ttatctcacg tgacagttgg agaattatca actgatcaat ataacaacac
      901 atctttcctt gtaagggatg atagtggtaa aagtatagtt gttcatatag atcatcgtac
      961 aggggttaaa ggggctgatg ttgttactaa aataagtcag ggtgatttga ttaacctcac
     1021 agccatattg tctattgttg atggtcagtt acaattaaga ccgttttctc ttgaacaatt
     1081 ggaagtggtt aaaaaggtca caagctcaaa tagtgatgct tcatctcgta atattgtgaa
     1141 aataggcgag attcaaggag ctagtcatac gtcgccactt ctcaaaaaag cggtcaccgt
     1201 agaacaggtt gttgtcactt atttagacga ttccactcat ttttatgttc aagatcttaa
     1261 tggtgatggt gatttagcga cttcagatgg tattcgtgtt tttgctaaaa acgctaaggt
     1321 tcaagtcggc gatgttttga ccatttcagg tgaagtggaa gaattctttg gtcgtggtta
     1381 tgaggaacgt aagcagactg accttaccat cacccaaatt gtggctaaag cagtgaccaa
     1441 aacagggaca gctcaagttc catcaccgct tgttttaggg aaagatcgta tcgcgccagc
     1501 caatattatt gataatgatg gcttgcgtgt gtttgatcca gaagaagacg ctattgatta
     1561 ttgggaatca atggaaggca tgttagtggc ggttgatgat gctaaaatcc ttggtccaat
     1621 gaaaaataaa gaaatttatg tcttacctgg ctctagtaca agaccgttaa ataattcagg
     1681 tggagtatta cttccagcta attcttataa cacagatgtg attcctgttc ttttcaaaaa
     1741 aggcaaacaa attattaaag taggagactc ttacaaagga agattagctg ggccagtatc
     1801 ttatagctat ggtaattaca aggtctttgt tgatgacagc aaaaacatgc caagtttaat
     1861 ggatggtcat ctaaaacctg aaaaaacaaa cttgcaaaaa gaccttagca agttaagcat
     1921 tgcttcttac aatattgaaa acttctcagc caatccttct tcaactaaag atgagaaggt
     1981 caaacggatt gccgaatcct ttattcatga tctgaatgct ccagacatta ttggattaat
     2041 tgaagtccaa gataataatg ggccgactga tgatgggaca acggatgcga cacaaagcgc
     2101 acaacgcctc attgatgcta ttaaaaaact aggtggccca acttatcgtt atgttgatat
     2161 tgctccagaa aataatgttg acggaggtca accaggtggt aatattcgaa caggattcct
     2221 ttatcaacca gagcgcgtca gcctttctga taagccaaaa ggcggtgctc gtgatgctct
     2281 aacttgggtt aatggagaat taaaccttag tgttggtcga attgatccaa ctaacgccgc
     2341 ttggaaagat gttcgtaaat cactagcagc agaatttatc ttccaaggtc gtaaagtcgt
     2401 tgttgttgca aatcatttga actctaagcg tggggataat gctctttatg gtcgtgtgca
     2461 accagtcact tttaaatctg agcaaagacg tcacgtcttg gctaatatgc tagcacaatt
     2521 tgcgaaagaa ggggcaaaac accaagctaa tattgtgatg ctaggtgact ttaatgattt
     2581 tgaattcaca aagacgattc aattaatcga agaaggtgat atggttaact tggtgagccg
     2641 acatgatatt tcagatcggt attcttattt tcaccaaggc aataatcaga cccttgataa
     2701 tatattagtt tcacgccatt tacttgatca ctacgaattt gacatggttc atgtgaattc
     2761 cccatttatg gaagctcacg gacgcgcatc agatcatgat ccattgttac ttcaattatc
     2821 attttccaaa gaaaatgata aggcagagtc ttctaaacaa agtgtaaaag ctaaaaaaac
     2881 ttcaaaagga aaactgttgc caaaaacagg agatagtctt gtttatgtga taacgctact
     2941 aggaacggct agtttattag tgcctatttt attattgact aaaggcaaaa aggaatcata
     3001 gcgatttgaa gaattggagt tcataaagag tcgttaaggg cttgatatac ttacgttaga
     3061 ccttaagcta aaatggatga ctatataaaa actaatattg ataacaaaag aagataacaa
     3121 taagacagct ttacttgcta aagacttttg tcaagctaat tgttttatgg tacaatgtaa
     3181 ccgttgcttt gcaacccttg gtgcttagtt ccctttcacc aagcatatta gaaacgtaga
     3241 tagcttttga gagttatcca gacgttaaag gagaaaaaat gacaaaattg actgtacacg
     3301 actatgttca cattgggcta gtagctgcct tgtatgttgt cttaactatt accccgcctt
     3361 taaatgcgat ttcttatggg atgtatcaat ttagaatatc tgaaatgatg aatttcttag
     3421 ctttttatca tcgcaagtat attattgcgg tgactcttgg atgtatgatt gctaactttt
     3481 atagtttcgg actgattgat gtctttgtag gcggcggttc aactcttatt tttgtgacct
     3541 taggtgttat tttgtttagt aagtatcaaa aagattatct ttttaatggc atttttaata
     3601 aagcttttgt ttacttttct ttcttttttg caacttccat gtttactgta gcaatcgaac
     3661 tttacttctt tggagctcca tttttattaa catggtttac aactgcgttg ggagaattag
     3721 tatctctgct cataggatca cttattattg ataagttgtc tcaaagaatt tccttttagt
     3781 aatgcatcat actcaaaaga gttgggtcaa tacccttctc ttttttatgt tgtttgtaat
     3841 gttaaaatcg ttctagatag aaatatttaa cactttagct aatagtacca tatggagtgg
     3901 ccaacgatta cttttgatgt tgttatgata tagaaatagc tcatttgtta tcttttatga
     3961 taaaataaaa gtatgaaaaa acgcataaaa gaattaacag atcttcttaa ccgttaccgt
     4021 tatgactatt atactaaaga tgccccatca gtttctgaca gtgactatga taagctttat
     4081 cgtgaactgg tgactttaga gcagtcatat cccgagtatg tcttgcaaga tagcccaacg
     4141 cagcaggttg gagggactat tttaaagggg tttgaaaaat atcgacatca gtatccgctt
     4201 tttagtttgc aggatgcttt ttcacgtgag gagctggatg cttttgataa gcgcgtcaaa
     4261 gccgaatttc caaatgccac ctatctagca gagttaaaaa ttgatggttt atctatttcc
     4321 ttgagttatg agaatggctt cttacaggtt ggagcaacac ggggtgatgg caatatcggt
     4381 gaaaatatca cagaaaatat caaaaaaata aaggatattc ctcaccaatt gagtgagcct
     4441 ttaaccatca ccgttcgagg agaggcttac atgtctcgtc agtcctttaa agcgatcaat
     4501 gaagcacgcc aagaaaatgg ggagactgaa tttgctaatc ctagaaatgc tgccgctggg
     4561 acactaaggc agctagatac gtcagtggtt gctaaacgtc aactagccac ttttttgtat
     4621 caagaagcta gtccgacagc tagaaatcaa caaaatgagg tcttagcaga attagcaggt
     4681 ctaggttttt cagtaaatcc gtattatcaa ctcacatcgt ctatggatga gatttgggat
     4741 tttatcaaaa ctattgaggc aaaaagagat caattagctt atgacataga tggcgttgtt
     4801 attaaagtta atagcctagc catgcaagaa gagctagggt ttacggttaa agctccacgc
     4861 tgggccattg cttacaaatt tccagcagaa gaaaaagagg cagaaatcct ttcggttgac
     4921 tggacagtgg gacgaacagg cgtggtcaca cctacagcga atctaactcc tgtgcaacta
     4981 gcggggacaa ccgtgagtcg tgcaacccta cataatgtgg attatattgc cgaaaaagat
     5041 atccgtattg gcgatacagt gattgtatat aaggcagggg acattattcc tgctgtctta
     5101 aatgtcgtta tgagtaagcg gaaccagcaa gaagtcatgc ttattcctaa actatgccca
     5161 tcttgtggta gtgaattagt tcattttgaa gatgaggttg ctttgcgttg tattaatccg
     5221 ttgtgtccta gtttgattca gcgaagtttg gagcattttg caagtcgtga tgccatgaac
     5281 attactgggc tgggaccagc tattgtggaa aaactatttt tagcggggtt tgttcatgat
     5341 gttgctgata tttaccagtt gaccaaagaa aatttcatgc aattagatgg catcaaagaa
     5401 aagtcagctg ataaattgct cgctgcgatt gaggcttcta aatcaaattc agctgaaaaa
     5461 ctgttatttg gtctaggaat tcgtcatatt ggctctaaag ttagtcgctt aattttagag
     5521 gtatacggag atatttctgc tcttttaacc gctaaagaag aggagatcgc aaggatagat
     5581 ggccttggct caacgattgc tcaatcactt actcaatact ttgaacaaaa aacggctgcg
     5641 attttagtag acgagttaaa gacagcaggt gtcaacatgc attactcagg tcaaaaagtt
     5701 aatagtgacg cagcgctttt tggtctaact gttgttttaa ctggcaaatt aaatcagctg
     5761 aaccgaaatg aggccaaaga taaattagag gcattaggtg ccaaagttac tggaagtgta
     5821 tctaagaaaa cagatttagt tattgcaggt agtgacgctg gttctaagct agaaaaagca
     5881 aagagcttag gaattcggat tgaagatgaa gattggctac gccagcttta agtgaggtaa
     5941 tgttatgaaa aaacaattga gagcacgtct catttataat ccaacgtcag gacaagaact
     6001 tatgagaaaa agtgttcctg aagttttaga catattagaa gggttcgggt atgaaacatc
     6061 tgcctttcaa acaacagccc aaaagaactc tgctctaaat gaagcaagaa gagcggcaaa
     6121 ggcaggtttt gacttattga ttgctgctgg aggtgatggc actattaacg aagtggtcaa
     6181 tggaattgct cccttgaaaa agcgccctaa aatggccatt attccaacag gtaccactaa
     6241 tgattttgct agagcgttaa aagtaccaag aggaaatccg agccaagcag caaaacttat
     6301 cggaaaaaat cagactatcc agatggatat tggtagagct aagaaagata cttatttcat
     6361 caatattgct gcagcaggaa gtttgacgga attaacttac agtgtaccaa gtcagttaaa
     6421 aacgatgttt ggatacttgg cttatcttgc taaaggagta gaactgctcc caagagttag
     6481 caatgtgcct gttaaaatta cgcatgacaa aggcgtcttt gaaggtcaag tttctatgat
     6541 ttttgcagct attaccaatt ctgttggggg atttgaaatg attgctcctg atgcaaaact
     6601 agatgacggt atgtttacgc tcattttaat aaagacagca aatctttttg aaattgtaca
     6661 tcttttgcgt ttgattttgg atggtggtaa gcatattaca gatcgccgtg tcgaatacat
     6721 taagaccagt aaaatagtca ttgaacccca atgtggtaag cgaatgatga ttaatttaga
     6781 tggtgagtac ggaggagatg ctccaattac attagagaac ctaaaaaatc atatcacttt
     6841 ttttgcagat actgatttga tttctgatga cgctttagtc ttagatcagg acgaattgga
     6901 aattgaggaa atcgtaaaga aatttgctca tgaagtagaa gacttagaac aagaattaga
     6961 agaataatac aatagttatt agctactgac agtttagtca aatgcactac tattagaatc
     7021 taagattttt aaatcaattg aggtagtgtt ttttgatgca ctcaaagagt caatttattc
     7081 atatgagggg cctatttgag gtctctcttt tttgatcata tgcaagaaaa tgccatgttt
     7141 taggggtgtt attataccct ttttggaatc ttgttgcctt tttgttataa taagagtgta
     7201 attctatttt taaaaagatc ttaacaaaga cagactcgtt tatcaaaaag gttagtatta
     7261 gtctaagaaa gcgtactcag tctaaagaaa tctgttgaca ttcttaattt taaggaatag
     7321 aatagcaaag taaaaaaaat ttaaaggagt attctactat gaatcctatt ttcgcattgg
     7381 ctttggcctg ttttggtgtt tctcttgccg aaggtttctt gatggcaaat ctttttaaag
     7441 cagcatctcg ccaaccagaa atcattggtc aattacgttc attaatgatc ttgggtgttg
     7501 cctttatcga aggtactttc tttgttaccc ttgttatggc cttcattctt aaataacagc
     7561 ctatttgata atagaaaagg agggtgttag atggaagaag ctaaaatacc catgctaaag
     7621 cttggtccaa taacctttaa tttgacccta cttgctgttt gtattgtcac aattgctgtt
     7681 atctttgcct ttgttttttg ggcaagtcgc caaatgaaat tgaaaccaga agggaagcaa
     7741 actgctttag aatatttaat cagttttgtg gatggtattg gagaagagca cttagatcat
     7801 aatctacaaa aatcttattc gctgttactc tttaccattt ttctctttgt ggctgtcgct
     7861 aataatttag ggttatttac taagttagag acagttaatg gctataacct atggacctcg
     7921 ccaacagcca atctggcttt tgaccttgct ctatctcttt ttattacctt aatggtacac
     7981 attgaagggg ttagacgtcg tggcttggtt gcccatttga aacgtttggc tacaccgtgg
     8041 ccaatgactc cgatgaattt attagaagag ttcacaaatt tcttatcact tgccattagg
     8101 ttattcggta atatctttgc cggggaagtt gttacaggtt tgattgttca actggccaat
     8161 tatcgagttt attggtggcc gatcgctttc ctagtcaata tggcgtggac agccttttca
     8221 gtctttattt cctgcataca ggcttttgtt ttcacaaaac taacagcgac ctatctagga
     8281 aagaaagtta atgaatcaga agaataagga aggagaacaa acgaatgtca atcacatttg
     8341 gtgaactcgt tgggaatttt attctagtaa caggttctgt aatcgtcttg ttactcttga
     8401 tcaaaaaatt cgcttggggt gcaattgaat cgattttaca gacacgctca caacaaatct
     8461 ctcgagatat tgatcaggct gagcaatcac gtctaagtgc tcaacagtta gaggcaaaaa
     8521 gtcaagctaa cctagatgct agtcgttcac aagcaagtaa aatcattagt gatgccaaag
     8581 aaattggtca attacaaggt gataaattgg tggcagaagc tactgatgaa gcaaaacgct
     8641 tgaaagaaaa agcgttgaca gatattgaac aaagcaaatc agacgctatt tcagcagtca
     8701 aaacagaaat gtctgattta acggttcttt tagcggaaaa aattatggga gccaatcttg
     8761 ataagacggc gcaaagccag cttattgaca gttatcttga tgacttagga gaagcttaat
     8821 gaccaaaaaa gaacaggctc ttatcgagca atatgcaaaa agccttgttg aggtggcaag
     8881 tgaacatcat tctcttgatg ccttacaagc tgatgtgctt gcgattttag agacgtttgt
     8941 aacaactaat cttgatcaaa gtctatcaag tctagctgtt ccgcatgctg aaaaaataaa
     9001 attgctaacc ttattaaagg gaaataattc tgtttatatg aataatttct tgaatctcat
     9061 tttacaaaac gaacgtgaag cttatttgta tcaaatgctt caggctgttt taaatgaaat
     9121 tgcaatagtt tcaaatcagt atgatgtgac agttacctca tcactacctt tgactgagga
     9181 gcaaaaaagc cgtgttcgag cagttgttgc aaagaaattt gctgtaacag cgggtcgttt
     9241 aattgaaaaa gtagatcctt cgcttattgg aggatttatt atcagcgtca ataataaagt
     9301 aattgatacc agtattcgtc gtcaattgca agcatttaaa atgaatttaa aatagaaagt
     9361 ggtgtgactt ttggcaatta atgcacaaga aattagcgct ttaattaaaa agcaaattga
     9421 gaacttccag ccaaatttcg atgtcacaga aactgggatc gttacctata ttggtgacgg
     9481 tattgcacgt gcccgtggat tagataatgc catgagtggt gaacttcttg aatttgaaaa
     9541 tggtgcctac gggatggctc aaaaccttga gtcaaatgat gtgggtatta ttattcttgg
     9601 tgatttttca gcaatccgtg aaggagatgt ggttaagcgc accggtaaaa tcatggaagt
     9661 accagttggt gaagctctca ttggacgtgt ggtaaaccca cttggacaac cagttgatgg
     9721 cttgggagat atcgaaacaa ctggctttag accagtagaa acgccagctc ctggtgttat
     9781 gcagcgtaaa tccgtttctg aacccttaca aactggatta aaagcaattg atgctttggt
     9841 tccaattggt cgtgggcaac gtgagttgat tatcggagac cgtcaaacag gaaaaacatc
     9901 cgtagctatt gatgcgattt tgaaccaaaa aggtcaagac atgatttgta tctatgtggc
     9961 tattggtcaa aaagaatcaa ccgttcgtac acaagttgaa acccttcgcc gttacggtgc
    10021 cttggattat actattgttg tgacagcgtc agcctcacaa ccatcaccat tgctctttat
    10081 cgctccttat gcgggtgttg ccatggctga agaatttatg taccaaggca agcatgtctt
    10141 gattgtctat gatgacttat caaaacaagc ggtggcttat cgtgaattgt ctctcttgct
    10201 tcgtcgtcca ccaggtcgtg aggcttaccc aggggatgtt ttctacttgc atagccgtct
    10261 tttggaacgc tctgcaaaag tttctgatga tttaggtgga ggttctatca cagctctacc
    10321 atttatcgaa acacaggccg gagatatctc tgcatatatt gcgactaacg ttatttcgat
    10381 tacagacgga caaatcttct tgcaagagaa cctctttaat tcaggaattc gtccagcgat
    10441 tgatgcagga tcatctgtct cacgtgtagg tggttcagct caaattaaag cgatgaaaaa
    10501 ggttgctggt actcttcgtt tggatttggc ttcctatcgt gaattagaag cctttaccca
    10561 atttggttcg gaccttgatg ctgcaacaca agcaaaactt aatcgtggtc gccgtacggt
    10621 tgaaatcttg aagcaaccat tgcataaacc gttacctgtt gaaaagcaag tcgttattct
    10681 ttatgccctt actcatggtt tcttagatga tgttcctgta gatgatattt tggcttttga
    10741 agaagctctt tacgactact ttgacgttca ttacaatgat ttatttgaaa ctatccgtac
    10801 cacaaaagac cttcctgaag aagctgccct tgatgccgct attaaagcgt ttaaagaaca
    10861 ctcaaacttt aagtcataga gggaggatac tagtatggca ggctctctaa gtgaaattaa
    10921 agctaaaatt atttcaactg agaaaacaag taaaatcact agtgccatgc gtatggtttc
    10981 ttctgcaaaa cttgttaaat ctgagcaagc agctcgtgat tttcaaattt acgcctcaaa
    11041 aattcgccag attactacag atttattgaa atcagaatta accataggat ctgataatcc
    11101 gatgttggtg tctcgtcctg tcaaaaaaac aggctatatt gtcatcacgt ctgataaagg
    11161 acttgttgga ggttacaatt caaaaatctt gaaatctgtt atggatatga ttacagagta
    11221 ccatgctgat ggtgactatg aaatcatttc tattggtagt gttggttcag acttcttcaa
    11281 agcaagaggg atgaatgtgg cttttgaact tcgtggactt gcggatcaac caagttttga
    11341 acaagtgaga caaatcattt cacaatccgt tgacatgttt gtcaatgaga tttttgatga
    11401 gttatatgtc tgttacaatc accatgtgaa tagcttaacc agccaagtcc gtgttcaaca
    11461 gatgttgcca atttctgact tggttgctga tgaagcagca gaagaaggtg ttactgggtt
    11521 tgaattagaa cctaatcgtc atgatatttt agatcaattg ttacctcaat tcacagaaag
    11581 tttaatttat ggggctatca ttgatgctaa aacggctgaa catgcagcag gtatgactgc
    11641 catgcagaca gcgacagata acgctaagaa tgtcattaac gatttgacca tccaatataa
    11701 ccgagctcgt caagcagcaa ttacacaaga aattactgaa attgttgcag gagcaaatgc
    11761 actagaataa aaaataacgc tgactagcga ttaggttatt gtcagcattc aattttatca
    11821 atcgagataa aatgacttat gggacttttc tattgaaaga ctgctctttt cagtataaaa
    11881 gaagttagca agactaacta agccctgact atcgaatata aggagaaatg aatgagctca
    11941 ggcaaaattg ctcaggttgt tggtccagta gtagacgtta tgtttgcgag tggggacaaa
    12001 cttccagaga ttaataatgc attgattgtt tataaagata gtgataaaaa gcaaaaaatc
    12061 gtccttgaag ttgctctgga acttggtgac ggtatggtgc gaacaatcgc tatggaatca
    12121 actgatgggc ttacacgtgg gttagaagtt cttgacactg gtcgtgcgat tagcgtacca
    12181 gtaggtaaag aaactttggg acgcgtcttt aatgtacttg gagaaaccat tgatttggaa
    12241 gaaccatttg cagaagatgt tgaccgtcag ccgatccata aaaaagcacc atcgtttgat
    12301 gaattatcaa catcatcaga aattcttgaa actggtatca aggtaattga ccttcttgcc
    12361 ccttacctta aaggtggtaa agttggactt ttcggtggtg ccggagttgg taagactgtc
    12421 cttatccaag aattaatcca caatatcgcc caagaacacg gaggtatttc agtatttacc
    12481 ggtgttggtg agcgaacacg tgaaggaaat gacctttact gggaaatgaa agaatcaggc
    12541 gttattgaaa aaaccgccat ggtttttggt cagatgaatg agccgcctgg ggcacgtatg
    12601 cgtgtagccc ttactggttt aaccattgct gagtatttcc gtgatgtaga aggccaagat
    12661 gttttgctct ttattgataa tatcttccgt ttcactcagg caggttcaga agtatcagcc
    12721 ctcttaggcc gtatgccttc tgctgttggt taccaaccaa cacttgctac tgaaatgggg
    12781 caattgcaag aacggattac atcaactcaa aaaggttctg ttacatctat ccaagcgatt
    12841 tatgtaccag cagatgatta tactgaccct gcgccagcaa cagcatttgc tcacctggat
    12901 tcaacaacta accttgaacg taaattgaca caaatgggga tttatccagc cgttgatcca
    12961 ttggcttcaa gttcacgggc tttatcacct gagattgttg gtgaagagca ctatgctgtg
    13021 gcaacagaag ttcaacgtgt gcttcaacgc taccgtgaat tacaagatat tattgctatt
    13081 ttggggatgg atgaattgtc agatgaggaa aaaacattgg ttggacgtgc gcgtcgtatc
    13141 cagttcttcc tctcacaaaa ttttaacgtt gctgaacaat ttaccggtct tcctggttct
    13201 tacgtgccag ttgctgagac agttcgcggc tttaaagaaa ttcttgaagg aaaatacgat
    13261 gatcttccag aagacgcctt tcgttcagtt ggtccaatcg aggatgtgat taaaaaagcc
    13321 gaaaaaatgg gcttttagtg aggtgatgcc atgacacaaa tgactgttca agtggtaacg
    13381 ccagatggaa tcaaatatga tcaccatgct aaatgtattt cggtaacaac accagatggg
    13441 gaaatgggga ttttacctaa tcacatcaat ttaattgcac ctttgcaagt ccatgaaatg
    13501 aaaattcgcc gaggtggtga agatgaaaaa gtggactgga ttgctatcaa tggtggtatt
    13561 attgaaatca aagataatgt ggttaccgtt gtcgctgatt ctgcagaacg tgaccgtgat
    13621 atcgatgtca gccgagcaga gcgagcaaaa ctaagagcag aacgtgaaat tgcacaggct
    13681 gaaacgaccc acaacattga tgaagttcgt cgtgccaagg ttgccttgcg ccgcgctttg
    13741 aatcgtatca acgttagtaa aaagtaagtg gtgttgataa aagacaagga taagtaagaa
    13801 aggtttttaa cctattattt tgtttgctga gtctttttaa catcagtttc tgagagtttg
    13861 accatactac cttctctaaa cacgttatta ttgttgagag gagttatatg ggggaactct
    13921 tttttgtatc cacgttgtta gtagaaactc agtaatgacg cttaatgtat ttttaggcta
    13981 tcaacttagt cagagaggat gtcaatttaa ttgataagtt ggacggatca agatggtatg
    14041 ttataataat cctatggaat tattaatgaa gatcattgcc ttttcgtgtc atttattttt
    14101 tattggcctt agttaccaat tattgattag tgtgattgac tggacaaaat ttagtcatta
    14161 tcatccagaa aatcttggcc ggctacgact ttttgtcttt ttattagcta ctgccctagg
    14221 gtatttggtg agccattgta tgctggaatt gcttcaaatt agccagacgc tcttttttga
    14281 gttctgctaa tactggaata aaagaagtat ggtataattt tactacgact aagagataga
    14341 taagggagaa aattgtggat aaaataatca ttgaaggtgg tcaaacacgc ttagaaggag
    14401 aagttgttat tgagggtgct aaaaacgcag ttcttccttt actggcagca tctattttac
    14461 cttcaaaagg aaaaacaatt cttagaaacg ttcctattct atctgatgtt tttaccatga
    14521 ataacgtggt acgtggttta gatattcgtg ttgattttaa tgaagcagct aacgaaatca
    14581 cagttgatgc ctcaggacac attttagatg aagcccctta cgagtacgtg agccaaatgc
    14641 gtgcctctat tgttgtttta ggaccaattt tggcacgtaa tggccacgca aaagtatcaa
    14701 tgcctggagg ctgtacgatt ggcagtaggc ctattaattt gcacttaaaa ggattagagg
    14761 ctatgggggc aacgattact caaaaaggtg gagatattac cgctcaagca gatcgactgc
    14821 aaggtgccat gatttatatg gacttcccat ctgtaggagc tacccaaaac ttgatgatgg
    14881 ctgccacttt agctgatggt gtgaccacta ttgaaaatgc tgctcgtgag cctgaaattg
    14941 ttgatttagc tcaatttttg aataaaatgg gagctagaat tcgtggtgct ggaacggaga
    15001 cgttaacgat aacaggcgtc acaagtcttc atggggtgga gcacgatgtg gttcaagacc
    15061 gtattgaagc aggtactttt atggttgcag cggcgatgac ttcaggcaat gttttgatta
    15121 gagatgctgt ttgggaacat aatcgtccat tgatttcaaa attaatggaa atgggtgttt
    15181 ctgtaacaga agaagaatat ggtattcgcg ttcaagcaaa cacgccaaag ctcaaacctg
    15241 taacggttaa aaccttgcct catccaggtt ttccaacaga catgcaagct caatttacag
    15301 ctttaatggc agtggtcaat ggagagtcta ctatggttga aactgtcttt gaaaatcgat
    15361 ttcaacatct ggaagaaatg cgacgcatgg gcttacaatc tgaaatcctt agagaaactg
    15421 ccatgattca tggtggaaga caactgcaag gtgctcctgt gatgtcaaca gatttacgtg
    15481 ccagtgctgc ccttatcttg acagggattg ttgctcaagg agttacaata gttaataatt
    15541 tggttcattt agatcgtggc tactatcaat ttcatgaaaa attagcaaag cttggagcta
    15601 ctattagtcg tagcagtgag gtctagctta tgacaaatgg tttaaaatat gtcttagaac
    15661 aaatgttatt acttttagta attgctgcct tggcgtgtct ttttttagcc attggactta
    15721 tgattggtta tagttttatg ggagatggcc atagtccatg gcatatttta tctatggata
    15781 agtgggcaga gttagtgaat aaatttactg gaaagtaggc cttgcctact ttttatagca
    15841 tctgagagga agtatgttaa caaggaaaaa acgaaaaagg gtgcaagagc aaaaggttcc
    15901 taaaagagct aatgccttac ttactaagtc aacccggcaa tatcaagacc gttcacaact
    15961 taagaaaggt taccgttcat ttaagccagc aggttggcac cgattgcacc acttaaaagg
    16021 aagttatgat cacgcggttg atagagggca tttgctaggt tatgctttag ttggtggact
    16081 gaaaggtttt gatgcttcta ctggtaatcc tgataatatt gccactcaac taagttgggc
    16141 taatcaagca aataaaccct actcgacagg tcagaattac tatgaaggtt tagtacgtcg
    16201 tgctttggat aaggggcatc gcgtccgcta ccgtgtcacc ctactttatg atggtgataa
    16261 tctactagcc agcggtagcc atttgaaggc taaatcctct gatgacagct tggcttttaa
    16321 cgtgtttgtt ccaaatgtcc aagcaggatt gaccgttgac tatcggacgg gacaaatagc
    16381 tatcaatctc taagcgaaaa gtcactgatt taagattgtc actaagcact ttttttgata
    16441 gaatagaact aattgaataa gtgtctatga gactagtact aatagagaaa ttaacaggga
    16501 gtgagggccg tgactggaag ccttcttaag ggaactatta ggaattcact cagctaaaga
    16561 caattaatta aggtctgata acatcagata aaaacggatg gtaccgcgtg tcaacgctcc
    16621 gcttatcaag tggaggagtg gcatgctttt ttcatcgcca aaagaaggga aaactatgga
    16681 tttacaagca caattagagg aattaaagtc aaaaacattg gagaccttac agtctttgac
    16741 gggtaatcat accaaagaac tgcaagattt acgcgtggct gttcttggga aaaagggatc
    16801 tttgacagaa ttactaaagg ggctaaaaga cttgtctaat gacttgcgtc ctgtggttgg
    16861 taaacaggtg aacgaagttc gtgacttatt gacaaaagcc tttgaagaac aggccaaaat
    16921 tgtagaagct gctaaaattc aggcccaact tgatgctgaa agcattgatg tgactttacc
    16981 gggtcgtcaa atgactctgg ggcatcgtca tgtgttgaca caaaccagtg aagaaatcga
    17041 agatattttc ttaggaatgg gttttcagat tgttgatggc tttgaggtgg aaaaagatta
    17101 ttacaacttt gagcgcatga atttgccaaa ggatcaccct gcccgtgaca tgcaagatac
    17161 attttatatc acagaagaaa tattgttacg aactcatacc agtcctgtgc aggcccgtac
    17221 tcttgatcaa catgattttt caaaagggcc tttaaaaatg gtttctccag gtcgtgtttt
    17281 ccgtcgtgat actgatgacg ctacccactc acatcaattc catcaaattg aaggtttggt
    17341 tgtgggcaaa aatatttcca tgggagacct caaagggact cttgaaatga tcatcaagaa
    17401 gatgttcggt gaagaacgta gcattcgttt gcgcccgtca tatttcccgt tcacagaacc
    17461 atctgttgaa gtggatgttt cttgctttaa atgtggtggg aaaggctgta atgtctgcaa
    17521 gaaaacagga tggattgaaa ttcttggtgc tggtatggtt cacccaagtg tcttggaaat
    17581 gtcaggtgtt gatgcaaaag agtattcagg ctttgccttt ggtttaggtc aagagcgaat
    17641 tgccatgttg cgttatggca ttaatgacat tcgtggtttc tatcaaggcg accaacgttt
    17701 ctctgaacaa tttaactaaa acgagtcgtt tgaagacctc tgtcagctat tttatctaag
    17761 attgagtaaa agttgatagg taatgataat aggttaattg tctaaggaga aagtccctct
    17821 cgcttcaacg tcataagggt tttgacttgg aacttaaaat acgaaaggaa atgactcaaa
    17881 tcacggcttg agagctttct ctagccgagt gatttgggca ctaaaattat gttagtatct
    17941 tataaatggt taaaagaatt agtagatatc gatgtgacac cagtagcact tgctgagaaa
    18001 atgtcgacaa cgggtatcga ggtagaagga attgaagtcc ctgcagaagg tttatcaaaa
    18061 ctggttgtgg ggcatgtgct ttcttgtgaa gatgtgccag agacacattt gcatttgtgt
    18121 caggtagata caggtgatga aacgccacgt caaattgtgt gtggcgcacc aaatgtgaaa
    18181 gcagggatta aggttatcgt ggctgtgcca ggtgctcgta ttgcggataa ctataaaatc
    18241 aaaaaaggca aaatccgcgg catggaatct cttggcatga tttgttcctt gcaagaactt
    18301 ggtttgtcag atagtatcat tccaaaagaa ttttcagatg gtattcaaat cttgccagag
    18361 gaggctgtgc caggtgatgc tatttttaaa tacctggact tggacgatca tatcattgaa
    18421 ttgtccatta cacctaaccg tgctgatgcg ctttctatgc gaggtgtggc acatgaagtc
    18481 gcagctattt atggcaagtc agtatcattc ccccaaaaaa atctacaaga atctgataag
    18541 gcaacttcag aagccattga attgtccatt gcctctgata acgttctaac ttacgctagc
    18601 cgtgtcgttg aaaatgtcaa agttaagcca agtccacaat ggttgcaaaa ccttttaatg
    18661 aatgctggta ttcgtcctat taataatgtg gttgatgtga ccaactatgt actcttgtat
    18721 cttggtcaac ctatgcatgc ttttgattat gataaatttg aagaccataa gattgtggcg
    18781 cgtgcggctc gtcaaggaga aagtttggtc acacttgatg gtgaaaaacg ggatttgacc
    18841 actgaggatc ttgttattac cgtggctgag aaaccagttg ctttagcagg tgttatgggt
    18901 ggtcaagcca ctgaaattga tggcaactct cagacggttg ttcttgaagc tgctgttttt
    18961 gatggcaaat cgattcgtaa aaccagtggt cgtttaaacc ttcgttcgga atcctcttca
    19021 cgttttgaaa aaggggttaa ctatgcaact gttttagaag cgcttgactt tgcagcggct
    19081 atgttacaag aattagcaga aggtcaagtc ttatcaggcc atgttcaagc tggacaattg
    19141 ccaacagaac ctgttgaagt ctcaactagc cttgactatg tgaatgttcg tttaggaaca
    19201 gaattaactt ttgctgatat tcaaaggatt tttgaccaac ttggatttgg tctaacagga
    19261 gatgaaacaa gcttcacggt agctgttcct cggcgtcgtt gggatgttag catcccagct
    19321 gacttggtgg aagaaattgc gcgtatctat ggttatgata agttgccgac aaccttacca
    19381 gaggcagggg gaacggctgc agaattaacg ccaacacagg ctcttcgtcg taaagtccgt
    19441 ggcttagcgg aaggattggg cttgactgaa atcatttcgt atgccttgac aacaccagag
    19501 aaagctgttg agtttgcagt ggcaccaagt cacctaacag aactcatgtg gccaatgtct
    19561 gtggaacgtt cagcgcttcg tcaaaatatg gtttcaggga tgttagatac ggtagcttat
    19621 aatgtggctc gtaaacaaag taacttggct ctttatgaaa ttggaaaaat ctttgaacaa
    19681 gaagctaatc caaaagaaga ccttcctaat gaagtgaacc attttgcttt tgctatttgt
    19741 ggcttagtgg cacaaaaaga tttccaaacc caagctcagg cagtggattt ttaccatgct
    19801 aaaggtatct tggatacttt atttgcaaac cttaacctca aggttcaata tgtgccaacc
    19861 aaagacctag caaacatgca cccaggacgg acagcgctta tcctattaga tgagcaagtg
    19921 attggatttg ttggtcaagt tcatccagga acagcaaagg cttatagtat tccagaaacc
    19981 tatgtggcag aattggatat ggctgcttta gaagcagcgt tgccaagtga tcaaactttt
    20041 gcggaaatca caaaattccc tgctatgaca cgtgatgttg ccttgttact tgaccgtgag
    20101 gtgagtcatc aggccattgt aacagctatt gaatcagcag gtgtaaaacg cttgactagc
    20161 attaaactct ttgacgtcta tgaaggagca accattcagg ctggcaaaaa atcaatggct
    20221 tatagcctta ctttccaaaa tccaaatgac aatttaacgg atgaagaagt tgccaaatac
    20281 atggagaaaa tcaccaaagc attgacagaa caagtcggtg ctgaagtacg ctaagaaaaa
    20341 aactgggcct ctaaggctcc gtttttttct gttataatag aggaaaaaag aactccagtt
    20401 caaatgattg gagaaaaaca tcagaaggtg gaggaaaatc agaatgtatc aaacaaaaat
    20461 aacaggcaac cgcctttacc acacggtttc gaaaggctac ggagatagtg taaccttatt
    20521 tggaaaaact gatcaagggg aaacccctat gagtttactg gttattgcct tgtcttcttg
    20581 tgtgactatg tgtgtgcagg gtttttacca tcgtcaattt cagcaagaca cagttgctgt
    20641 ttctgttgag gctagttatg aggaagaagt ttttgaacta cttgttagga ttgatgatgt
    20701 tttagatgac aaaaagaaag ctgatttatt ggcttacatt ggaacttatt gtcgtgtgaa
    20761 acaactcctc aaacctgaag ttacggtgac cattacgttg gaaggattgt ctcatgtctg
    20821 atgctagttt gaaaacttac caaaaacaat gggcttatca aaagtattgg gtcatggcac
    20881 actcacagca gcattacaat gctttaagag aattgtttaa aggaaatcag tggtcagaag
    20941 aaaaggtgtt gacttttcat tgtttgattg aagaagcgca agccattcct cccacagtaa
    21001 aaagcttacg aacggcatat cagcatgttt gggggtattt taaaaaggta gcgagtcagg
    21061 aagaaaaaga ccatttcaaa gatttggatg ctcagttgga aactaaatct gaggagatgc
    21121 tatgcttttt acaagagatg actgctcatt atcagccctc ttatctgcta tcttgccgtt
    21181 tgattaccaa aggtccttaa atgctaaaca gaaaagtagg gatttctggg aagttatgct
    21241 aagctagtga tataaataag ggggaatgag agatgttttt agcgcttaat gaaatgaaac
    21301 aatccaaatt gcggtatggt ttgattgctg gtttgctatg tttggttgcc tatttgatgt
    21361 tctttttgtc aggattggcc tttggtttga tgcaggagaa ccgctcggcg gttgatcttt
    21421 ggaaagctga cagtgtttta ctagccaagg atgctgacgc taccttgacc ttatcacagg
    21481 tgtccagagc tcaagaaaat caaataacag cagacaaggt agctcctctt gctcaactca
    21541 ataccgtggc gtggtcagtt aaaaatccta aggatgccga caaagttaag gttagacttt
    21601 tcgggattga ttctaatagc tttattcgtc ctaacattgt aaaaggtcga ttatttaaga
    21661 ctaacaaaga ggttgttttg gatcaaagcc ttgcaaaaga ggaagctttt gcgattggca
    21721 aggactttta cacatcgagt tctagtcaag cattaactat cgttggttat actcaaaatg
    21781 ctagatttag tgttgcacca gtggtttata tgaatttgga agcttttgaa acattaaaat
    21841 atggagaacc actaccaaaa gataagcaag ttgttaatgc ttttatcact aaaggaagtt
    21901 taacagatta tcctaaaaaa gacttccaaa aattagatat taaaaccttt attactaaat
    21961 tacctggtta tagcgctcaa cttttaactt ttggctttat gattagtttt cttgtcatta
    22021 tttcagctat tattattggt atttttatgt atattttgac tattcaaaag gcacctattt
    22081 ttgggattat gaaagcgcaa ggtatcggga atataacgat tgcacaagca gttctgctgc
    22141 aaaccttctt gttaagtgct ttaggaagcg gtttagggtt attgggaact tggttgacgt
    22201 ctttagtgct ccctgaagca gttcccttcc aaagtaattg gctagtttac ttagcgatat
    22261 tagtcagtat ggtttgtttt gctttgttag gaaccttatt ttctgttttt agcattgtac
    22321 gaattgatcc tttgaaagca attggatagg aggtagtgat gtcggtttta acatttaaac
    22381 aagtgaccaa aacatttcaa gatggtcatc acgaaatcaa cgcattaaag gcaactgact
    22441 tttccattga agctggagaa tttgtggcta ttattggacc atcaggttct ggaaaatcaa
    22501 cctttttgac cattgctggt ggcttacaga ccccaagctc tggtcagcta atcattgatg
    22561 gcactgatta tacccattta tcagaaaaag agcgctcacg cttgcgcttc aaatccgttg
    22621 gttttatctt acaagcttcc aatctgatac cttttttaac ggtccagcag cagttggaat
    22681 tggtcgatca tttgacagga agcaaagaaa aagccaaagc caatcagtta tttgacgatt
    22741 taggcattgc agggctaaaa catcagttac ctcaagaatt gtccggcgga gaaaggcaaa
    22801 gagcggctat tgcccgtgct ctttaccatg atccagcact gatattggca gacgaaccta
    22861 ctgcaagttt ggatactgaa aaagcctatg aagtggtcaa actgttggct aaggaaagta
    22921 aagaaaaaaa caaagccatt attatggtca ctcatgatga tcggatgcta aaatattgtg
    22981 acaaagtcta tcggatgcaa gatggagagt tacgtcaaga gagatagtag actggtaaga
    23041 gtttatgata ttagaagaaa aaaccaaaca agcacagcac ttgtctggtt tttttctaag
    23101 tgtgactatt atcaatacgt caccatttcc ctaaagctta ctatacggga tgctaaaggt
    23161 atcaccatgc tcaaagtcgc catattggta acctcggtca aaccaacgtt ggcgttgctt
    23221 agaagttccg tgggtaaaac tatcaggaac ggctctgcca taggtttctt cttgcagagt
    23281 atcatcccca actgcgtgag ctgctgccat tgcttcctca atatctcctt tttccaaaag
    23341 gccttgccct tgaacataat tagcccaggc accagcatag taatcagctt gtaattccaa
    23401 cttgacgttg agctgattgg ctttagcctt tgattttcct tgtctagtgc tagcgtaatt
    23461 atccataatt cccaattcat tttggatgtg gtggccaact tcatgagcaa tcacataggc
    23521 catagcgaaa tcaccttttg cgccgtactt ggttgatagt tcattataaa aagaaatatc
    23581 taaatacact ttttgatcgc ctgggcaata gaaaggacca gaagaggctt gccccctgcc
    23641 acaagcggtt tgagttgctc cagtatatag aactaatgtt ggtttatgat aagttaaccc
    23701 tttctcacga aatgtcttag tccaatagtc ctcggtagag gcgaagacct tactgacaaa
    23761 agaaacctgt tcttgactag ccttgtcacc atttgtacgc gttacttggc ttgattgata
    23821 ggcattgttg ttggtagaag aaggcttgcc tcctaaaaca ccagataggc cacctcctcc
    23881 cataactagg agaaggagaa gaataaccag cttggttttc caacctcctc gtgaaaagag
    23941 taattgaagc aggagaccgc cccctaggcc gccgccccca aaagaaccag acgattgacc
    24001 acgtctatct tcaacctgtt gactttctct caaatcatcc gttttcataa gtttctccca
    24061 tctatttctt gattttatta taaaataatt ctattagaat tgctattttt atgatgagat
    24121 tataactaaa aataggaaaa gcaataggta tttgctataa tataacaagg gtagattcag
    24181 tttgtataaa ggagtcatat gaaattaatt tacacagaga tgagttactc gatgacagag
    24241 attttggtga atgaagcacg aaaagctgct gaccaaggtt atcgagtgtt ctatattgct
    24301 ccaaattctc tttcatttga aaaggaaaga gaagtcttaa ccttattgcc tgaacgaggg
    24361 actttttcga taatagtcac ccggttcgtt caaatgtcaa ggtattttac agttgagagc
    24421 tctccttcta agcaacatct agatgacacg actttggcta tgatttttta tcgggccttg
    24481 atgcaattaa aaccagaaga tttgccgagt tatggtcgtt tgcaaaataa ttcggttttt
    24541 attgaacaac tagttgagtt atataaggaa ttaaaaaacg cacaattaag cgtacatgat
    24601 ttaacagggt tagaccatcc tcaaaaacaa gaagatctta ttaaaattat tgagcttgca
    24661 gagacgatca tgattcagca agattacaat caagatagtc ctctacaatc ttttgcaaga
    24721 gcaattaagt taggactttt aaataatcaa ctatcaaaaa cagttattgt tattgatggt
    24781 ttttcacgtt tttcagctga agaggattat ttattatcac ttttaaataa caactgtcaa
    24841 gaggtcatca ttggcagtta tgtgagtcaa aaagcttatc aaaaatcttt tattaaggga
    24901 aatatctatg aggctagcct tcattttttg caagatttgg ctcaaaaata ccatatcaag
    24961 ccggtatttg cgacctctaa tcaagtgttt aaaccagcct tttcacggct aacacaatta
    25021 tttgaagcaa ctcatgattt ttcacaagta gactggcaac tccaaaagaa tgatcttgat
    25081 cactttagcc tttggcaatg tcatcatcaa aaagaggaaa ttgaacatgt agcaaaatcc
    25141 attcggcaaa agctatatga aggttaccgt tataaggata tcttagtgtt gctaggagat
    25201 atggatgctt atcaattaca aattgggcct atctttgata agtttgaaat cccctactat
    25261 ttaggaaaag cagagcctat ggctgcccat ccattagtcc aatttataga atcgctcgaa
    25321 cgaagtcagc gctataattg gcgtcgtgaa gacattttaa acatgttaaa atcaggactt
    25381 tttggttgtt ttgatgatag tgatattgat cgctttgagg aatatactca gtttgcagat
    25441 attaaaggat ttactaaatt ttcaaagcct tttaccatta actcttctag gcagtatcct
    25501 cttgactttt taaatgaaat gagacaagac atcgttttac ctttgcaaga attgtttaag
    25561 agtcaaaaac agcttggtgc ttcacttatt gacaaattaa tacttttttt agaaaagatt
    25621 agattagctg agaatatgca aggtttagca cagtcccaat tagaggtgga aaaaaacgaa
    25681 gaagtttgga aaaggtttac agatattttg acttcttttc atcatatttt tggccaagaa
    25741 aaattacggc tatcagattg ccttgcttta atcaaaacgg gaatgaaatc agctcagtat
    25801 cgtgttgttc cagcgacatt agatgttgtc actattaaat cttatgacct tgttcaacca
    25861 cattcaaaac ctttcgttta tgcaattggt ctaactcaat cacattttcc taagcaaatt
    25921 caccattcag gactactttc tgatcaagag cgtgctagaa ttaatgaaat aagaaattat
    25981 cgtcattttg atattgctag tgccgaaaat agtaaaaaaa accatcaaac tgcgttatct
    26041 ctgtttaatg ctgctactaa agagttagtt cttagtgttc caacggtaat caacgagaca
    26101 ttcgatgatc tatctcctta tcttaaagaa ttaataaact ttgggttacc tcttttggat
    26161 aaaggcaaaa actatctatc ttatgataat agcgatattg gtaactataa agctctcttg
    26221 tcacaaatta ttgctattaa ccgacaagat cttatagaaa tgtcagatca agataagatg
    26281 ttttggactg ttgtcttacg ttatctcagg aaacagttaa gaaagcaaca gctagagcta
    26341 cctacttcag attatcgttt atcaacaaag cctttgtcta aagaagttat cgaggtatgt
    26401 tttccaaagg gaatcccttt aaagctatct gcaactgctt taaccgtttt ttataataat
    26461 cagtacaact attttttgaa atatgttttg aatttaaaca aaacagaatc cattcatcca
    26521 gattccagaa ttcatggtca atacttgcat cgtgtctttg agcggttaat gaaagatcac
    26581 acgcaagaac cgtttgataa taagttaaaa caagcaatct accataccaa tcaagaaagt
    26641 ttttttcagc aggtttacca agataatgcc gaggctgagt acagtttagc tatactagaa
    26701 gatattgtta gatcaacagc acctatcttg caacttaacc aaaacataaa ggtcattgat
    26761 caagaaaaga actttcatct ggatatggga aatgagatat tagtccacgg gatcattgat
    26821 cgtattgacc agctgagcga cggtagcttg ggcattgttg actataaatc aagcgcgaat
    26881 caatttgata ttgggacctt ttataatggg ttgagtccac aactagtgac ttacctcgca
    26941 gccttaaaac agatcgcacc gcacgatata aaccaattat ttggggctat gtaccttcat
    27001 ttgcaagatc ctaaattgga tctagtaaca tttaaacaaa ttgataacac attagtggag
    27061 agtatctata aagcgttgac ctataaaggt attttttcag aagtcgaaaa agagcatcta
    27121 tctactggtg cttaccaaac caaaaatgct ctttattcca atgacgaatt ggaaacactt
    27181 ttaaattata acaagtacct ctatcttaaa gctgctaaac acattaaaaa gggacatttt
    27241 ttgattaatc cttatacaag cgatggtaag acagttcaag gagatcaatt aaaagccatt
    27301 acccgttttg aagcagatct tgacatggca caggcaaggc gactagtgac tctccctgct
    27361 aaggagaaaa aagagtgctt tttaacatta atgagaaagg agagccactt gtgatttctt
    27421 ttgccccatt tttaagcccc gaagctatta aacatttaca agaaaacgaa aggtgcagtg
    27481 atcagtctca aaaacgcaca gctcaacaaa ttgaagcaat ttatactagt ggccaaaata
    27541 tacttgtatc agcttctgct ggttcaggaa aaacctttgt aatggtcgaa cgcatacttg
    27601 ataaaatttt gagaggtgtt tcaattgatc ggctttttat ctcaaccttt actgttaaag
    27661 cagctacaga actgcgtgaa cggattgaaa acaaattata ctcacaaatt gctcaaacta
    27721 cagattttca aatgaaagtt tatttaacag aacaattgca atctcttggt caagctgata
    27781 ttggtactat ggatgctttt gcacagaaag tagtaagtcg ctatggttat agcattggca
    27841 tttcatccca atttcgtatc atgcaggata aagcagaaca agatgtttta aagcaagagg
    27901 tgtttagcaa actctttagt gagtttatga atcaaaaaga ggcaccggtg tttagggctc
    27961 ttgtgaaaaa tttttctggt aactgtaaag acacttcagc ttttagagag ttagtttata
    28021 cttgttattc ttttagccaa tcgacagaaa atccaaaaat atggttgcaa gaaaattttc
    28081 taagcgctgc taaaacttac caaagacttg aagatatccc ggatcatgat attgaactct
    28141 tacttttggc aatgcaagac actgcaaatc agctaagaga tgtgactgat atggaagatt
    28201 atgggcagct gactaaggca ggtagccgat ctgctaaata cactaaacac ttaacgatca
    28261 tagaaaagtt gtctgattgg gtgcgtgatt ttaaatgttt gtatggaaaa gccggattgg
    28321 atcggttgat cagagatgtg acaggcctta taccatctgg gaatgatgtt acagtctcga
    28381 aggtaaaata ccctgttttt aagaccttgc atcaaaaatt aaaacaattt aggcatttag
    28441 aaacaatttt aatgtatcag aaagactgtt ttcccttatt ggaacagtta caagattttg
    28501 tgcttgcgtt ttcagaagct tatttagctg tcaaaataca agaaagtgct tttgaatttt
    28561 cagatattac acactttgca atcaaaattt tagaggaaaa tacggatatt cgccaatcct
    28621 atcagcaaca ctatcatgag gtgatggttg atgaatatca agataacaat catatgcaag
    28681 agcgactcct gaccttacta tcgaacggtc ataatcgctt tatggtagga gatatcaaac
    28741 aatcgatcta tcgatttcgg caagccgatc ctcagatttt taatcaaaag tttagagact
    28801 atcaaaaaaa aactgagcag gggaaagtga ttttactcaa agaaaacttt cgtagccaat
    28861 cagaggtgtt aaatgtcagc aatgctgttt ttagtcactt aatggacgaa tcagtaggag
    28921 acgtcttata cgatgagcaa catcagttaa tagcaggtag tcatgctcaa acagtcccct
    28981 atctagaccg tcgtgctcag ttattgctat ataatagcga taaagatgat ggcaacgccc
    29041 cttcagatag tgagggtatt tcatttagtg aggttacaat tgttgccaaa gaaattatta
    29101 agcttcacaa tgataagggt gtcccttttg aagacattac gttactcgtt tcttcaagaa
    29161 caagaaatga tatcatttct catacattca atcaatatgg tattcctata gtaacagatg
    29221 gtgggcagca aaactatctt aaatctgttg aagtgatggt tatgttagat acattacgca
    29281 ccattaataa cccaagaaat gattatgccc ttgtggcttt actgcgctca ccgatgtttg
    29341 cctttgatga ggatgattta gcaagaatag cacttcaaaa agacaatgag ctagataaag
    29401 attgcctata tgacaagata caaagggctg tgattggaag aggtgctcat cctgaattga
    29461 ttcacgatac cttgcttggc aagttaaata tttttttaaa gacgttgaaa agttggcgtc
    29521 gatacgctaa gctagggtcg ttgtatgact tgatttggaa aatttttaat gatcgttttt
    29581 attttgattt tgtagctagt caagcaaaag cagaacaagc acaagctaat ctatacgcat
    29641 tagctctacg tgctaatcag tttgaaaaat cgggctataa agggctatac tgttttatta
    29701 aaatgattga taaggtactt gagacgcaaa atgacttagc agatgtggaa gtggctgctc
    29761 ctaaacaagc tgttaattta atgaccattc acaagtctaa aggtttacaa tttccgtatg
    29821 tatttatcct taattgtgac aagcgcttct caatgacaga tattcataaa tcatttattc
    29881 tgaatcggca gcacggtatc ggtatcaagt accttgcaga tatcaaaggt ttacttggtg
    29941 aaacaacact caattctgtt aaagtaagca tggaaacctt accttatcaa ttgaacaaac
    30001 aagagttgcg cttagcaact ttatcagaac aaatgcgctt attgtatgtt gctatgacac
    30061 gagctgaaaa aaaagtttat tttattggta aagctagtaa gagcaaaagt caagatatca
    30121 cagatcctaa aaagttaggc aaacttttgc cgctggcttt acgagaacag ttattgacat
    30181 tccaagattg gctattagca atagcagatg tattttcaac tgaagatctt tattttgatg
    30241 ttcgctttat tgaagatagt gatttgacac aagagtcagt cggacgactt caaacaccac
    30301 agttattaaa tccagatgat cttaaagata atcgtcaatc agaaacaatt gcacgggctt
    30361 tagatatgtt agaagcagtg tctcaattga atgccaatta tgaagcagct attcatttgc
    30421 caacagttcg aacgcctagc caacttaagg cagcttacga gcctttatta gaacccattg
    30481 gtgtagatat tatagagaaa tcttctcgat cgctatctga ttttactttg ccacattttt
    30541 caaaaaaagt aaaagttgaa gcaagtcata ttggatcagc tcttcatcag ttgatgcagg
    30601 tgctcccttt gtcaaaaccg ataaatcaac aaacgctttt agacgcttta agagaaattg
    30661 atagtaacga agaggtaaaa acagctcttg atctcaaaaa aatagagtcg ttcttttgtg
    30721 atacaagcct aggccaattt tttcagactt accaaaaaca cttgtatcga gaagcaccat
    30781 ttgctatttt aaaagttgac cctattagtc aagaagaata tgtcctacgt ggtattatag
    30841 atgcctactt tttgtttgat gatcatattg tattagtgga ctataaaaca gataaataca
    30901 agcagcccat tgagttaaaa aagcgttacc aacaacagtt ggagttatat gcagaagctc
    30961 tcactcaaac gtataaactt cctgtgacta agcgctatct tgttttaatg ggaggtggaa
    31021 agccagaaat tgtcgaagtt taaggttgtt gtgacacaag ggtattttgc aaatgataat
    31081 agtatagttg aggattttac gaaatgcttg aaaagctatt gacctttgaa taataataca
    31141 atataataag ttttattagt gacaaaaagg aataaatata ctatgaattt taaaaaaata
    31201 agatttggtt ttttgctttg cctcctactt tatcctttag cagcttgtaa caagtctgaa
    31261 caacttaatc actacgaaag aattaaaaaa acaagaaaat tagtcgttgc tgtaagccct
    31321 gattatgctc cttttgaatt taaagcttta gttaatggaa aagatactat tgttggagca
    31381 gatgttcaat tagctcaggc tattgctgat gaattagacg tcgatcttga gctttcacca
    31441 atgagttttg ataatgtttt gtctagttta cagactggta aagctgatct tgctatttca
    31501 ggaatctcac atactaaaga aagagctaaa gtatatgatt tttcaattcc ttactatcag
    31561 gcagaaaacg ctatagtgat gagagcatct gatgctaaag tgaccaaaaa tattagtgac
    31621 ctaaacggta agaaagtagc cgctcaaaaa ggtagtatcg aggaaggttt agttaaaata
    31681 caattaccaa aggccaatct gatttctttg actgctatgg gagaagccat taatgaacta
    31741 aaagcaggac aagtctatgc agttacctta gaagcacctg tagctgctgg ttttttagcc
    31801 caacataagg atctggcttt agcacccttt agcttaaaaa ccagtgatgg agatgccaaa
    31861 gcagtggccc ttcctaaaaa tagtggtgac ttaaccaaag ccgttaataa ggttattgct
    31921 aagttagatg agcaagaacg gtacaagtca tttattgcag agacaatagc actaacgaaa
    31981 aatactatga agtaataagg ttaataaaaa ctttattagt atccgttgga aaagtgttta
    32041 gaataaacaa taaaagaggt ttgacttttt ttaaaaaata atgtaatata attgggaacg
    32101 tgaaaatgtt acaatatctt gaggaggtga aacacatgtc aaaaacagta gtacgtaaga
    32161 atgaatctct tgacgatgct cttcgtcgct tcaaacgttc tgttactaaa gctggtactc
    32221 ttcaagaatc acgtaaacgt gaattctacg aaaaaccttc tgtaaaacgt aaacgtaaat
    32281 cagaagcagc tcgcaaacgt aaaaaattct aatggtaaaa aataaaaaca gttctcacaa
    32341 ttagaactgt ttttattttt tatccagaag aagcaaggga gcttttttga tatcaaaaaa
    32401 agcagttaga catgcctaac tactttatca aaaatcgctt tatttttgag ccaacaaatc
    32461 acggatttct gtcaataatt cttcttgagt aggagctgca gcttcttttt cttttttagg
    32521 catagctttt tcagcggctt ttacaacaaa gaaaagactg gtaccgatga taagaaaatt
    32581 aataacggct cctaaaaagc taccatattt aacaccattc catgacaatt gagtgatgtt
    32641 ttcaacattt gcagccttca gagctgggtt taaaataagc ggtgtgataa tatcgttcac
    32701 aaaagaagtg acaatagcac caaaagctcc cccgatgata actgctacag caagttcaat
    32761 aatgtttcct ctaaacaaaa atgcttttaa ttctttaacc attaaatatt ccccctttta
    32821 atatctctaa gttaagcata gcataattag taaacaaaat ccaatggaat cacttcagtt
    32881 tttaaattta caaaaaagag tttcggtggt ataataaaac gtaaaactaa aatgggattt
    32941 ttatggggag gtgacgattt ggcaattgac aaagaaatga tttcccaagt aaaaaatagc
    33001 gttaatattg tcgatgtcat tggagaagtg gtcaaacttt cccgatcagg gcggcattat
    33061 ctcgggcttt gcccatttca taaggaaaag acaccctctt tcaatgttgt tgaagacaga
    33121 caattttttc actgctttgg ctgtggaaaa tcaggggatg tttttaaatt tattgaggaa
    33181 taccgccaag tccccttctt agaaagtgtt cagattattg ccgataagac tggtatgtcg
    33241 cttaatatac cgccaagtca ggcagtactt gctagccaac acaagcaccc taatcacgct
    33301 ttgatgacac ttcatgagga tgctgctaaa ttttaccatg cagttttgat gaccactacc
    33361 attggtcaag aagctaggaa gtacctttac cagagaggct tggatgacca attaattgag
    33421 catttcaata ttggtttagc cccagatgag tcagattatc tttatcaagc tctttctaaa
    33481 aaatacgagg aaggtcaatt ggttgcttca ggattgttta acttgtccga tcaatccaat
    33541 accatttacg acgcctttcg aaatcgtatc atgtttccct tatcagatga ccgagggcat
    33601 attattgcct tttcaggacg tatctggacg gcagctgata tggaaaagag acaggccaag
    33661 tataaaaatt caagaggaac agttcttttt aacaaatctt atgaattgta tcatctggac
    33721 aaagcaaggc ctgttattgc caaaacccat gaagtgtttc taatggaagg gtttatggac
    33781 gtgattgccg cttaccgttc cggctatgaa aatgctgttg cttcaatggg gacggcattg
    33841 actcaagaac atgtcaatca ccttaagcaa gtcactaaaa aagttgtttt gatttatgat
    33901 ggtgacgatg ctggacaaca tgctattgca aaatcactag aattgcttaa agattttgtt
    33961 gtcgaaattg tcagaatccc caataaaatg gatcctgacg aatttgtaca acggcattcc
    34021 ccagaagcat ttgcagattt gcttaagcag tcacggatca gtagtgttga attttttatt
    34081 gattacctaa aacctactaa tgtagacaat ctgcaatcac aaattgttta tgtggagaaa
    34141 atggcaccat tgattgctca atcaccatcc atcacagctc aacattcgta tattaacaag
    34201 attgctgatt tgttgccaaa ctttgactat tttcaagtag aacaatcagt aaatgcatta
    34261 aggattcaag ataggcaaaa gcgtcaaggt caaatagctc aagccgtcag caatcttgtg
    34321 accttaccaa taccaaaaag tttgacagct attgctaaga cagaaagtca tctcatgcat
    34381 cggctcttac atcatgacta tttattaaat gaatttcgac atcgtgatga tttttatttt
    34441 gatacctcta ccttagaaat actttatcaa cggctgaagc aacaaggata cattacatct
    34501 tatgatttgt cagagatgtc agaggaaatt aaccgtgctt attacaatgt tttagaagaa
    34561 aaccttccca aagaagtagc tcttggtgag attgatgata ttttatccaa acgtgccaaa
    34621 cttttagcag agcgcgatct tcacaaacaa gggaaaaaag ttagagaatc tagtaacaaa
    34681 ggcgatcatc aagcggctct agaagtacta gaacatttta ttgcgcagaa acgaaaaatg
    34741 gaatagagga aattatgaca aaacaaaaag aaataacaac ttttaacgtt caagttgcgg
    34801 agtttattcg ccatcacaaa aaagaaggaa cagcgattga tgatgacgtg accgaaaaac
    34861 ttgtcattcc atttgctttg gatgctgatc agattgatga tttacttgag cggttaacag
    34921 atggtggtat ctcgattacg gataaagaag gtaacccatc atcaaaatac attgttgaag
    34981 aaccaaaacc agaagaatta actgatgaag aattaattgg tagtaattca gctaaagtaa
    35041 acgaccctgt ccgcatgtac ctcaaagaaa ttggtgtggt accgctttta acaagtgaag
    35101 aggaaaaaga attggctgtt gcagttgcca agggagattt aatggctaaa caacgtttag
    35161 cggaagcaaa ccttcgtctt gttgtctcaa ttgcaaaacg ttatgttgga cgtggaatgc
    35221 aatttcttga tttaattcaa gaaggtaaca tgggactcat gaaagctgtt gataaatttg
    35281 attattcaaa aggattcaaa ttctcaactt atgcaacatg gtggattcgt caagctataa
    35341 cacgcgcaat tgcagatcaa gcacgtacga ttcgtatccc tgttcatatg gttgaaacga
    35401 ttaataaatt agtccgtgaa caacgtaacc ttcttcaaga acttggtcaa gatccaacgc
    35461 cagaacaaat cgcagaacgt atggaaatga ctccagacaa ggttcgtgaa attctaaaaa
    35521 ttgctcaaga acctgtttct ttagaaacac caattgggga agaagatgat agtcacttag
    35581 gtgattttat cgaagatgaa gttattgaaa atccagtaga ttatacgacg cgtgttgttc
    35641 ttcgtgagca attggatgaa gttttagata cgcttactga ccgtgaagag aacgttcttc
    35701 gcctacgctt tggccttgac gatggtaaaa tgcgtacgtt agaggacgta ggtaaagtct
    35761 ttaatgttac tcgtgagcgc attcgacaga ttgaagctaa agcccttaga aaacttcgcc
    35821 atcctagtcg tagtaaacaa ttaagagact ttatagagga ctaaaatcgt ccagtggacg
    35881 attttaggtc gttcctttga aataagaaag gagcgaaaat cctaagtggc acttatcagc
    35941 ggtacaccta caaattagaa atcggaccga atgtggtggg tatttttaag gttggacttg
    36001 atatcttaaa caagcccaga gggcaattcc tctaaatagg caaagcttta gtggtttttt
    36061 tacttatcta cgacatattc aaaaaatgaa aggaaagcca tgtctgatac accaaaatat
    36121 acgcaagatc aggtgatagc tatcaagaat agaattcttg aagctttaga aactgttatt
    36181 gatcccgagc taggtattga tgttgttaat ctaggtttga tttatgaaat tcggttcaat
    36241 gataacggtt atacagagat tgatatgaca ctcacaacaa tgggttgtcc tttggcagac
    36301 ttgttgacag attacatcca tgatgccctg caagatgtgc cagaagtcac taagactgag
    36361 gtcaaattag tctggtaccc tgcttggacg gttgataaaa tgagccgcta tgctaggatt
    36421 gcgctgggta ttcgctaatc attgatagta aagggatgaa atattccctt ttttgatgta
    36481 gaataaaagg aaatacaggt gaaagccttt ggttaatgtt agagaacact aagatactga
    36541 gaaaagtgtt ctacctatgg caaaaaggag aactgatgat tttaattaca ggaagcaatg
    36601 gtcaattagg gacagaactt cgatacttat tagatgaacg aggtgttgat tatgtagccg
    36661 ttgatgtcgc agaaatggac atcacaaatg aagacaaagt cgaagctgtt tttgcgcagg
    36721 tcaagccaac attggtctat cattgtgctg cttatacggc agttgatgca gcagaagacg
    36781 aaggaaaagc cttgaatgag gctattaatg taacaggctc agaaaatatt gccaaggctt
    36841 gtggaaaata tggggctacc cttgtttaca tttcaacaga ctacgtattt gatggcaata
    36901 aaccagtcgg tcaagaatgg gtagaaacag atcgtccaga ccctaagaca gaatatggcc
    36961 gtacaaaacg tttaggagaa ctagctgttg aacgatacgc agagcatttt tatattatcc
    37021 gtactgcttg ggtatttgga aattatggta aaaactttgt ctttaccatg gagcagttag
    37081 cggaaaatca ctcccgtttg actgttgtca atgaccaaca cggtcggcca acgtggacaa
    37141 gaaccttggc agaattcatg tgttatttga cagagaatca aaaagccttt ggttactatc
    37201 acttgtcaaa tgatgctaag gaagacacca cttggtatga ttttgccaaa gaaatcttaa
    37261 aagacaaggc tgttgaagtg gtgccagttg attcatcagc tttcccagca aaagccaaac
    37321 gtcctttaaa ttcaaccatg aatcttgata aggcaaaagc aacagggttt gttattccaa
    37381 catggcaaga agccttgaag gcattttacc aacaaggact gaaaaagtaa gtattctaaa
    37441 aagagttggc tttctaaggc caactctttt tcatgggttt aaggtcgcat tagccttcta
    37501 attgtggtat aatatcactg attatatttt agaatggggt agtatgcaat gcaggatgtt
    37561 tttatcattg gtagcagagg gttaccagcg aaatacggtg gctttgaaac ctttgtcgaa
    37621 gagttgatta gtcatcaatc atctaaaaac attcgttatc acgttgcttg tttaagcgat
    37681 acgaagcata aggttcattt tgattataag ggggcagatt gcttttacct taatccccca
    37741 aaacttggtc ctgctagagt tattgcttat gatatgatgg caattaccta tgccctgtct
    37801 tatagcgacc aacaccagat tcagaaccct attttttatg tgttgggcaa tactgtaggc
    37861 gcttttattg cgccatttgt gaagcagatt cacaatcgag gtggacgctt ttttatcaat
    37921 ccagacgggt tagagtggaa acggtctaaa tggtcaaaac cagtgcaggc ctacctgaag
    37981 ttttccgaaa agcaaatgac tagacaggct gatttggtca tttcagataa tattggcatt
    38041 gaccgctacc ttaaacaggt ttatccttgg tctaaaacat gttttattgc ttatggaacg
    38101 cagacacaac cttcacgttt gacaacagca gatagcaagg tcagagctta ttttcaaacc
    38161 tttgatatta gagaaaagga ttactatctc attttaggac gctttgttcc tgaaaataat
    38221 tacgaaactg ctattaaaga atttatggct tcctcaacta agcgtgattt agtgattatt
    38281 tgtaatcatg aagacaatgc ttactttaag caattacttg ctgagacaga gtgtgataaa
    38341 gacccacgca ttaaatttgt tggtaccctt tatgacaaag aactattagc ctacattcga
    38401 gaacaggctt atgcctatat ccatggtcat gaggtaggag ggactaatcc aggccttcta
    38461 gaagcactag cccataccaa tcttaatttg gttttaggag ttgattttaa ccagtcggtg
    38521 gctaagtctg ctgcgctgta ttggtccaag caaaaagggc aattagcaga gctgattaac
    38581 caagttgatg caggttttga tagtgatcgt ctgggcaaag aagccaaagc tattattcaa
    38641 gaacattaca cttgggaaaa aattgtaggg gagtacgagg ctttattttt aaatgaacat
    38701 taatatttta ctatccacct acaatggaga acgcttctta gcagaacaaa ttcaaagtat
    38761 ccaaaggcaa acagttaacg actggacctt attgattaga gatgatggat caactgatgg
    38821 cacccaggat attattcgca catttgtcaa ggaagacaaa cgaattcagt ggatcaatga
    38881 ggggcagaca gaaaatctgg gagttattaa gaatttttac accctcttaa agcaccaaaa
    38941 agcagatgtc tattttttca gtgaccaaga tgatatatgg ttagacaata aactggaagt
    39001 gaccttattg gaggctcaaa aacatgaaat gacagctcct ttattggttt atacagacct
    39061 caaagtggta acccaacatt tagctatttg ccatgacagt atgattaaga cccaatctgg
    39121 tcatgcaaac acaagcctac ttcaagaatt aaccgaaaat accgtaacag gcggcacaat
    39181 gatgattact catgctctgg ctgaggaatg gaccacttgt gacggtttat tgatgcatga
    39241 ctggtattta gctttactag cttctgctac tgggaaatta gtttaccttg atattccaac
    39301 agaattatac cgtcagcacg atgctaacgt gttgggagct agaacttggt ctaaacgcat
    39361 gaaaaattgg ttaacccccc atcatttagt caacaaatat tggtggttga ttacttcaag
    39421 ccaaaaacag gctcaattac tattagattt accattaaaa ccaaatgacc atgaattggt
    39481 aacggcctat gtttctttat tggatatgcc ttttaccaaa cgcttagcta ccttgaaaag
    39541 gtacggtttt agaaaaaatc gcatctttca cacctttatt tttcgtagtt tagttgttac
    39601 cttatttggt tacaggagaa agtaagaatg aattttttaa caaagaaaaa ccgtatttta
    39661 ctgagagaaa tggtaaaaac ggattttaaa ttacgctatc aagggagcgc aattggctat
    39721 ctatggtcta tcttaaaacc gcttatgatg tttacgatta tgtacttggt atttattcgt
    39781 tttcttcgcc tgggtggaaa tgtacctcat tttccagtag cgcttttatt ggcaaatgtc
    39841 atctggtctt ttttttcaga agcaactagc atgggaatgg tatctattgt atctcgggga
    39901 gacttgttgc gaaaattgaa cttttctaag cacatcattg ttttttcggc agtgttagga
    39961 gctttaatta attttcttat taatttggtt gttgttttaa tttttgcgtt gataaatggt
    40021 gtgactatat cagggtatgc ttatctctct ctttttcttt ttatagaatt agttgtttta
    40081 gtgcttggaa ttgcattgtt attgtcgaat gtctttgttt attatcgtga cttagctcaa
    40141 gtctgggaag tactattaca agcaggtatg tatgccactc caatcattta tccgatcact
    40201 tttgttttag atagccaccc tttggcggca aagttgttga tgctaaatcc agtagcacaa
    40261 atgattcaag attttcgtta tttattgatt gacagagcca acgtaacgat ttggcagatg
    40321 tcaaccaatt ggttttacgt tgttattcca tatttagtac catttgttat attatttatt
    40381 ggcatctttg tctttaagaa aaatgccgat agatttgcgg agattattta atgattaata
    40441 gagaaattgc agtaaaagta cagcatgtta gtaaaacatt taaactgcct acagaagcaa
    40501 ctaaaagttt tcgcacgact ctggttaatc gcctaagagg gattaaagga tttactgaac
    40561 aacatgtgct aaaagatatt aactttgatg tttataaagg cgattttttt ggaattgttg
    40621 ggcgtaacgg ctcgggaaaa tcaacgctcc ttaaaattat ttcccagatc tatgttccag
    40681 aaaaaggaca ggttacagta gatgggaaga tggtttcttt tatagagctt ggagtgggat
    40741 tcaatccaga attaacagga cgagaaaacg tctatatgaa cggcgccatg ctgggattta
    40801 ccaaagacga agttgatgat atgtacaatg atattgttga ttttgcagag ttgcatcatt
    40861 ttatgaatca aaaattaaaa aattattctt ctggcatgca ggtacgttta gcattttcag
    40921 tggctattaa agcccaaggt gacgttctta ttttagatga ggtgcttgct gtaggagatg
    40981 aagcttttca gcgaaaatgt aatgattatt ttatggaaag aaaagacagt ggtaagacga
    41041 ctattttagt gacacatgat atgggagctg ttaagaagta ttgtaaccgt gcagttctta
    41101 ttgaagatgg tcttgttaaa gcatatggag aaccatttga tgttgctaat cagtatagtg
    41161 tagataatac agagacagct gaggatgcaa tgaatgctga aaaaatatct gtatctgata
    41221 ttgccaaaga tttgaaagtg tcattaatct caaatccaag aataacacca aatgacacaa
    41281 tcacatttga agtttcttat gaagttttaa aagatgattt tacctacatt gccttttctt
    41341 taacggatat tgatagaaac atttgggttt acaacgacaa ttctttagat tatccaacac
    41401 aaggtatagg tagaaaatgc atttcctacc aatgtcaact atctcaactt aatgatataa
    41461 aactaaaatt agaagtaact gtccgagata agaacggtca gatgctactc ttttcaacag
    41521 cagaacaatc accccagata gtgattcaaa gaaacgatat tgatcaagat gatctgtcag
    41581 ctctagattc agcaagtggc ttgtatcaac gtaatgggaa gtgggttttt cattaatgag
    41641 taatagctag aagggaattt atgtataaag tttcaattat ttgcaccaat tataacaaag
    41701 ctccttggat atctgatgca cttgacagtt ttttaagcca agtgacagat tttgaggttg
    41761 aaattattgt tattgatgat gcttctacag atgactcacg agagatttta aagagttatc
    41821 aaaaaaagtc ttcaggaaaa attaaattac tctttaacga aactaatatt ggaataacaa
    41881 agacttggat aaaagcatgc ctttatgcaa aaggcaaata tattgctaga tgtgatggtg
    41941 atgattactg gacggatagt tttaaactcc aaaaacaagt tgatgtctta gaagcttcca
    42001 aacggtcacg atggtgtaat actgattttg actttgtaaa tagtcaaggc gacttattat
    42061 atgctaatgc tttttcatct ggtcatacac ctttgacaga tacttacgaa aaagttttag
    42121 ccttaaaagg gatgacgatg gcatcgacat ggttagttga tgctgattta atgagacaag
    42181 taaaccaaaa aatcaatgta gatacaccag acgatacttt tgacattcaa ctagagttat
    42241 ttcaactgac tcaactgacc tatattaaag actcaacgac ggtttatcgc atgacaaccg
    42301 attctgattc aagacctact gatacaccaa aaatgattca tcgtattcaa aaactacttg
    42361 atactcagtt aaattactta aaaaagtata atcaggtaga tacaaaagaa atgtctgaac
    42421 tattattaca acaagatgct aagcaagaaa tacgaattca tgagttgagt tgctttattc
    42481 aagaattaca acaaactatc gtagataaaa caaagcagca agaaacacgt gaagtggagt
    42541 tgcaaaatgt catagaagaa caaaaaaatc aactatctga attaagacaa caataccatg
    42601 ccattattaa ttcacgtcaa tggaaataca cgtctaagct cattgctttt attaggagaa
    42661 aaaaatgaat cgtattttat tatatgttca cttcaacaaa tacaataaaa taagtgcaca
    42721 tgtttactat caattggaac aaatgagatc actgttttct aagattgttt ttatctcaaa
    42781 tagtaaagtg agtcacgaag atttaaaacg tctcaaaaac cactgtctta ttgatgagtt
    42841 tttgcaacgc aaaaataaag gttttgattt ttctgcatgg cacgatggct tgattactat
    42901 gggatttgac aagttggaag agtttgactc attgacgatt atgaacgata cttgttttgg
    42961 tcctatttgg gagatggctc cttattttga aaattttgaa gaaaaagaga cagttgactt
    43021 ttggggaatt actaataata gaggtacaaa agcttttaaa gaacatgtcc aaagttattt
    43081 tatgacgttt aaaaatcaag tcattcaaaa caaagttttt caacaatttt ggcaatcgat
    43141 aatagaatat gaaaacgttc aagaagtgat tcagcattat gaaacgcaat taacatccat
    43201 tctcttaaat gaaggcttta gttatcagac ggtctttgat actagaaaag ctgagtcgtc
    43261 attcatgcca catccggatt tttcatatta taatccaaca gcaattttaa aacaccatgt
    43321 gccttttata aaagtaaaag ctattgatgc taaccagcat atcgctcctt acttattgaa
    43381 tctgatacga gaaacaacca attatcctat agatcttatt gtttcacata tgtcgcaaat
    43441 ctctttgcca gatgctaagt accttttatc tcaaaaatac ctaaactgcc aacggttagc
    43501 aaaacaaact tgtcaaaagg tagctgttca tttacatgtt ttttacgttg atttgctaga
    43561 tgaattttta acagctttcg aagactggaa cttccattat gatcttttta ttacaacaga
    43621 tagtgatatc aaaagaaaag agatcaaaga aatacttcaa agaaaaggta aaactgctga
    43681 tatacgcgtt acgggaaata gaggaagaga tatttatcca atgttattac taaaagataa
    43741 actttctcaa tatgattata ttggtcattt ccatacgaaa aaatcaaaag aagctgattt
    43801 ttgggcagga gaatcttggc gaaaagaatt gattgatatg ctcgtgaaac cagcagatag
    43861 tattcttagc gcttttgaga caaatgatat tggtattata atcgcagata ttccaagttt
    43921 ttttagattt aataagattg tcaatgcttg gaatgagcat ttaatcgctc aagaaatgat
    43981 gtctttgtgg agaaaaatgg atgttaaaaa acaaattgat tttcaagcta tggatacatt
    44041 tgttatgagt tatggaacat ttgtatggtt taaatacgat gctctaaaat cactttttga
    44101 tttagaatta actcaaaatg atattccaag tgaaccttta ccacaaaact ctatattaca
    44161 tgcgattgag cggttacttg tctatatagc gtgggggaat tcttatgatt ttaggattgt
    44221 taaaaatccc tatgagttaa caccttttat tgacaataaa ctgttaaatt tacgtgaaga
    44281 tgaaggagct catacctacg ttaactttaa tcaaatgggc ggtatcaaag gagcattaaa
    44341 atatattatt gttggtcccg ctaaagcaat gaagtatata ttcttgcgtt taatggagaa
    44401 acttaaatga ttaaagacac atttttaaaa accaattggt taaatattag tcaccatatt
    44461 acccttcttg ttttcggttt ttatttcagt ttttatagtt tggcgaaaga actagtaagc
    44521 tccacggcac aaccggtaaa ctattatact catttactaa atgtttcttt tgtgggatat
    44581 attatatcac tgattggatt atcttattat ttgagtcgcc aagttagtcg acagttgttt
    44641 ttgaaaacta gttttattgt gatatcttat ctaattgtca gctattgggt acaaataaca
    44701 cagcacctga atgataaacg gtttgatatc tggtcattaa ctaaaaatca attttatcaa
    44761 tttcaagctc taccttcttt actcattatt ttagtgatgg ccactttaat aaaaatattg
    44821 gtagcatatt ttgcaataga aaaagataga tttgggctat taggctatca aggtaatact
    44881 ttttctgtag ctctgatttt agcagttgtg ccaattaatg acatacatct gttaaaacta
    44941 ataagttctc gattttctga attagtaaga gcaggtaata gccaaattgc actgttaaaa
    45001 ataagtggac tgttgatagt tttacttgtc atatttgcaa caatcatata cgtggtttta
    45061 aatgctctaa aacaccttaa gtcaaataaa ctttcatttt cagtagcagc tactactagt
    45121 ttgtttttag cattagtttt taactatacg tttcagtatg gcgtaaaagg tgatgaagca
    45181 ttgctaggat attatgtttt ccctggagct actctttttc agatagtagc tattacacta
    45241 gttgctattt tagcatacgt gataacgaat agatattggc caactacctt ctttttgctt
    45301 attctgggaa caattatttc tgttgttaat gatttaaaag aatcaatgag aagcgagccg
    45361 ttattagtaa ctgattttgt ttggttacaa gaattaggtt tagtgacaag ctttgttaaa
    45421 aaatcggtga ttgtagaaat ggttgtagga cttgctattt gtattgtggt agcttggtat
    45481 ctacatggcc gagttttagc agggaaatta tttatgagcc ctgtcaaacg ggcaagtgct
    45541 gtattaggtt tatttattgt atcttgtagt atgttaatac cattttctta tgaaaaagaa
    45601 ggtaaaatat tatctggtct tccgattatt tcggctttaa ataatgataa tgatataaac
    45661 tggttaggtt tttcaacaaa tgctaggtac aaatctttag catatgtttg gacaagacag
    45721 gtgaccaaga aaataatgga aaaaccgaca aattatagcc aagaaacaat agcgagtatc
    45781 gctcagaagt accaaaaatt agcagaagat attaataaag acagaaaaaa taatattgct
    45841 gaccaaacgg ttatttatct tttaagtgaa agtttgtcag atcctgatag agtatcaaat
    45901 gttactgtta gtcacgatgt tttacctaat atcaaggcaa tcaaaaatag cacaactgcg
    45961 ggactcatgc agtcagactc ctacgggggt ggaactgcta acatggagtt tcaaacgtta
    46021 acaagcttac ctttttataa tttttcttct tcagtatctg ttctttattc agaagtcttt
    46081 cctaaaatgg ccaaacctca tacgattagt gagttttacc aaggaaaaaa tcgtattgcg
    46141 atgcatcctg ctagtgctaa caattttaat agaaaaacag tttatagtaa tttaggtttt
    46201 tccaaattct tagctctatc gggttctaag gataagttta agaacattga aaatgtcggt
    46261 ttattgacta gcgataaaac tgtctataat aatattttat ctttaattaa tcctagtgaa
    46321 agccaatttt tctcagttat tacaatgcaa aatcatattc cttggtcatc cgattatcct
    46381 gaagaaattg ttgctgaagg aaaaaatttc acggaagaag aaaatcacaa cctaacaagt
    46441 tatgctcggt tattatcgtt tactgataag gaaacaagag catttttaga aaaattaaca
    46501 caaattaaca agcctatcac agtggtgttt tacggagatc atttacccgg tttatatcct
    46561 gatagtgctt ttaacaagca tattgaaaat aaatacctta ctgattattt tatttggagt
    46621 aatggtacta acgagaaaaa aaatcatccg cttatcaact caagtgattt tactgcagct
    46681 ttatttgagc atactgattc aaaagtatca ccttactatg ctttgttaac agaggtactg
    46741 aataaagcta gtgtcgataa atcaccagat agtcctgaag ttaaagctat tcagaatgat
    46801 ttaaaaaatg tccaatacga tgtgactata ggaaaaggtt accttttgaa acacaaaact
    46861 ttttttaaga tatcacgtta agaaaaatgc taggctgtcc gagtatagac gagcatcaag
    46921 gtttggtaat ttgctcaaat gattgtcaac agagtatcta gggccaggtt taaaagatta
    46981 taattcttaa ggtcttattc gtttataaaa aatgaatact cttttaaaat cttaattgaa
    47041 atgaatagga gaagttttcg tgaaaaagtt aatcattatt cctgcttaca atgaaagcag
    47101 taatattgtc aatactatac gtactattga atcagatgcc tcggattttg actatatcat
    47161 tattgatgat tgctcaacgg ataatacgtt agcaatatgt caaaaacagg ggttcaatgt
    47221 tatttctttg cccattaacc tgggaattgg cggtgcggtg caaactggct atcgttatgc
    47281 acaaagatgt ggatatgacg ttgcagttca agtagatgga gatggtcagc acaatccatg
    47341 ttatttggaa aaaatggttg aggtattagt tcaatcttca gtaaatatgg taattggatc
    47401 acgatttatc acaaaagaag ggtttcagtc atcatttgct cgacgtatcg gcataaagta
    47461 ttttacatgg cttattgcgc tactaacagg aaaaaaaata acagatgcaa cgtcaggtct
    47521 aaggttaatt gaccgttcat tgattgaacg ttttgctaat cattatccag atgattatcc
    47581 tgaacctgaa acagttgttg atgtattggt tagtcatttt aaagtgaaag aaattcctgt
    47641 tgtaatgaat gagcgacaag gcggtgtgtc atctatctca ttgacgaaat cggtctatta
    47701 tatgattaaa gtgactttag ctattttagt tgttagattg aaaggaaatc gttaaaatga
    47761 cggtaacagc cagtttattt ataagtttta ttgtattaac ctttgttttc tttttgatta
    47821 acttaatcaa aaaagacaaa ctagcgatta agtactcttt attgtggttt attttagctt
    47881 tattaatttt actatttacg tggttaccta acatattaaa taaaatgtct cacttcctgg
    47941 gtattcattc accaaccaat atgctattct ttttaggttt ttgtttgagt ttagctatta
    48001 ttttttcact gactaataat atctcacttc aaaatgataa agtaaaacgt ctgacccaag
    48061 aagtggccct tatgaaaaaa gagaaaacca atgattaatc cttcaaaaca aaaccaaacg
    48121 atttttttat ggaatatgtt aggaagttta tcaacagctg taatatcagt tatattactt
    48181 atggtggtta ctaggttact aacttcggct gattcagata tttacgcctt tgcctattct
    48241 tttgctaata tgatggtagt tgttggactt tttcaggttc gtaattatca agcaacagat
    48301 attaatgaaa aatattcctt tagtcagtac ttagtggcaa gactgatgac ttgtttatta
    48361 atgttagcca taacagtaat ttatttaacg ttaactaaga cagatagcta caagagtaca
    48421 attgtctttc tagtctgttt ctatagatcg acagatgctt tttcggattt atatcaggga
    48481 atgttccaac aacatgaacg gctggatatt gcaggtaaat cgctagctta cagaaatact
    48541 cttattttta tggtgtacac agcaataata ttatattcca aaaatcttac tttagcatta
    48601 gtagctgtct gtatagtttc attagttttt ataatgta
//
LOCUS       DAUGUF010000012        46506 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUGUF010000012 DAUGUF010000000
VERSION     DAUGUF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46506
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.012"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..1141
                     /locus_tag="VIB71_000667"
     CDS             <1..1141
                     /locus_tag="VIB71_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEQ8822419.1"
                     /translation="FVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAYIS
                     KQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQEGDGFGGV
                     TIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDTETAHLYGE
                     LAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLNLFSYTAAF
                     SVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKL
                     IFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFK
                     KQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            1138..1824
                     /locus_tag="VIB71_000668"
     CDS             1138..1824
                     /locus_tag="VIB71_000668"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEQ8822420.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            1918..3084
                     /gene="aroC"
                     /locus_tag="VIB71_000669"
     CDS             1918..3084
                     /gene="aroC"
                     /locus_tag="VIB71_000669"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEQ8822421.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            3145..3486
                     /locus_tag="VIB71_000670"
     CDS             3145..3486
                     /locus_tag="VIB71_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEQ8822422.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            3707..5059
                     /gene="gorA"
                     /locus_tag="VIB71_000671"
     CDS             3707..5059
                     /gene="gorA"
                     /locus_tag="VIB71_000671"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEQ8822423.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKKIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKAIVDVLVEEM
                     AVGGPCLHSHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFGLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKIDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(5147..6415)
                     /locus_tag="VIB71_000672"
     CDS             complement(5147..6415)
                     /locus_tag="VIB71_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8822424.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(6445..6885)
                     /locus_tag="VIB71_000673"
     CDS             complement(6445..6885)
                     /locus_tag="VIB71_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822425.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITISRALQPVPDKTSNDTPKESSNTIVKIIEKESSQSNQNHTGTSETTDDNKTTLP
                     SSSTAPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTKP"
     gene            7120..8262
                     /locus_tag="VIB71_000674"
     CDS             7120..8262
                     /locus_tag="VIB71_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ8822426.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNSLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            8274..9488
                     /gene="thiI"
                     /locus_tag="VIB71_000675"
     CDS             8274..9488
                     /gene="thiI"
                     /locus_tag="VIB71_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEQ8822427.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAIAVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTKITPEIV
                     NDEVENLIDALL"
     gene            9526..10818
                     /locus_tag="VIB71_000676"
     CDS             9526..10818
                     /locus_tag="VIB71_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEQ8822428.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    10923..10997
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            11032..11346
                     /gene="rplU"
                     /locus_tag="VIB71_000677"
     CDS             11032..11346
                     /gene="rplU"
                     /locus_tag="VIB71_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEQ8822429.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            11358..11684
                     /locus_tag="VIB71_000678"
     CDS             11358..11684
                     /locus_tag="VIB71_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEQ8822430.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            11712..12005
                     /gene="rpmA"
                     /locus_tag="VIB71_000679"
     CDS             11712..12005
                     /gene="rpmA"
                     /locus_tag="VIB71_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEQ8822431.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            12353..13267
                     /locus_tag="VIB71_000680"
     CDS             12353..13267
                     /locus_tag="VIB71_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8822432.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            13264..13722
                     /locus_tag="VIB71_000681"
     CDS             13264..13722
                     /locus_tag="VIB71_000681"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEQ8822433.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            13712..14602
                     /locus_tag="VIB71_000682"
     CDS             13712..14602
                     /locus_tag="VIB71_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ8822434.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            14998..15519
                     /gene="pyrR"
                     /locus_tag="VIB71_000683"
     CDS             14998..15519
                     /gene="pyrR"
                     /locus_tag="VIB71_000683"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEQ8822435.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            15535..16794
                     /locus_tag="VIB71_000684"
     CDS             15535..16794
                     /locus_tag="VIB71_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEQ8822436.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            16855..17790
                     /locus_tag="VIB71_000685"
     CDS             16855..17790
                     /locus_tag="VIB71_000685"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEQ8822437.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            17834..18916
                     /gene="carA"
                     /locus_tag="VIB71_000686"
     CDS             17834..18916
                     /gene="carA"
                     /locus_tag="VIB71_000686"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEQ8822438.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            19162..22338
                     /gene="carB"
                     /locus_tag="VIB71_000687"
     CDS             19162..22338
                     /gene="carB"
                     /locus_tag="VIB71_000687"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEQ8822439.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            22544..23815
                     /locus_tag="VIB71_000688"
     CDS             22544..23815
                     /locus_tag="VIB71_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ8822440.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            23815..24525
                     /locus_tag="VIB71_000689"
     CDS             23815..24525
                     /locus_tag="VIB71_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822441.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            24537..25757
                     /locus_tag="VIB71_000690"
     CDS             24537..25757
                     /locus_tag="VIB71_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822442.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKLALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            26011..27744
                     /locus_tag="VIB71_000691"
     CDS             26011..27744
                     /locus_tag="VIB71_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEQ8822443.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            27871..28143
                     /gene="rpsP"
                     /locus_tag="VIB71_000692"
     CDS             27871..28143
                     /gene="rpsP"
                     /locus_tag="VIB71_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEQ8822444.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            28153..28392
                     /locus_tag="VIB71_000693"
     CDS             28153..28392
                     /locus_tag="VIB71_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEQ8822445.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            29324..32350
                     /locus_tag="VIB71_000694"
     CDS             29324..32350
                     /locus_tag="VIB71_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEQ8822446.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTLGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLNTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGKGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRALQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            32370..32771
                     /locus_tag="VIB71_000695"
     CDS             32370..32771
                     /locus_tag="VIB71_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEQ8822447.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(32965..33840)
                     /locus_tag="VIB71_000696"
     CDS             complement(32965..33840)
                     /locus_tag="VIB71_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEQ8822448.1"
                     /translation="MPVSKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESSNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLKESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSGIEVN"
     gene            33976..34497
                     /locus_tag="VIB71_000697"
     CDS             33976..34497
                     /locus_tag="VIB71_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8822449.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLEFIK"
     gene            34712..35230
                     /gene="rimM"
                     /locus_tag="VIB71_000698"
     CDS             34712..35230
                     /gene="rimM"
                     /locus_tag="VIB71_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEQ8822450.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DRFVQEVTIVSHRKQKHFDIIKFKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYH
                     QIIGMAVYEKDVLIGHVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLSVDVPNKRV
                     DVELMEGLDDED"
     gene            35220..35939
                     /gene="trmD"
                     /locus_tag="VIB71_000699"
     CDS             35220..35939
                     /gene="trmD"
                     /locus_tag="VIB71_000699"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEQ8822451.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALG"
     gene            35951..36943
                     /locus_tag="VIB71_000700"
     CDS             35951..36943
                     /locus_tag="VIB71_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ8822452.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYTSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKTSTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            37121..38179
                     /locus_tag="VIB71_000701"
     CDS             37121..38179
                     /locus_tag="VIB71_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEQ8822453.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNRFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGNSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            38192..39115
                     /locus_tag="VIB71_000702"
     CDS             38192..39115
                     /locus_tag="VIB71_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEQ8822454.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     IVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
                     ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            39371..40084
                     /locus_tag="VIB71_000703"
     CDS             39371..40084
                     /locus_tag="VIB71_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8822455.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQLIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            40081..40992
                     /gene="pfkB"
                     /locus_tag="VIB71_000704"
     CDS             40081..40992
                     /gene="pfkB"
                     /locus_tag="VIB71_000704"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEQ8822456.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISREQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFVKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            40989..42935
                     /locus_tag="VIB71_000705"
     CDS             40989..42935
                     /locus_tag="VIB71_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8822457.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGHTYHAKNGKSET
                     AVSSEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPKDQLGNLGSY
                     HEVAAIFMKIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGTIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            43028..43627
                     /locus_tag="VIB71_000706"
     CDS             43028..43627
                     /locus_tag="VIB71_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8822458.1"
                     /translation="MKVKKRRRRARSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            43779..44486
                     /locus_tag="VIB71_000707"
     CDS             43779..44486
                     /locus_tag="VIB71_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ8822459.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(44543..44854)
                     /locus_tag="VIB71_000708"
                     /pseudo
     CDS             complement(44543..44854)
                     /locus_tag="VIB71_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(45058..45423)
                     /locus_tag="VIB71_000709"
     CDS             complement(45058..45423)
                     /locus_tag="VIB71_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822460.1"
                     /translation="MPSTDDGILRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEF
                     DFKIRKFLMESKEIHLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVLKKYKD
                     NKTINMKDFSHFDIYLWTK"
     gene            complement(45443..46468)
                     /locus_tag="VIB71_000710"
     CDS             complement(45443..46468)
                     /locus_tag="VIB71_000710"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEQ8822461.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSN
                     GNLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQ
                     DSWNQTN"
BASE COUNT        14723 a         7686 c         9622 g        14475 t
ORIGIN      
        1 ttttgtcgaa aagaagctga cagcaggggt acaattatta gatgaaaaag atttttctaa
       61 tataaaggaa aaaaatcagt tggttcaact ggtgaccaag tccaatcgtc ccattggaac
      121 agcatatatc tctaagcaaa ataaaggaat tggttggtat ctaggaccag aaaaaatcga
      181 cttgtctatc tcttattttg ttagtctatt ttcagttgct aaggccaaaa gacaagattt
      241 tgctcaatcg gacgagacca atgcttatcg cctttttaat caagaaggag acggttttgg
      301 tggagtaaca attgatcttt ataaagattt tgcagtcttt tcatggtaca atgcctttgt
      361 ctatgacaaa aaagaaatga ttatggaggc ttttcaacag gtttttcctg aagtcaaagg
      421 agcttatgaa aagtgtcgct ttaaaggtcc agatactgaa actgctcatc tgtatggtga
      481 gctggcacaa gaaacctttt cgattttaga aaatggcata gcctatcaag tcttcttgaa
      541 tgagggctta atgacaggta tttttctaga ccagcatgat gttagaagag cactagtaga
      601 tggtttagct atgggcaagt cccttcttaa cctattttcc tatacggctg ccttttctgt
      661 agcagctgct atgggtggtg ctatcgagac cacttctgtg gacttggcta aacgatcgag
      721 agaattatca ctagctcatt ttgagcataa ccagttaaac ttagcctcac atcattttgt
      781 ggtgatggat gtttttgaat acttcaaata tgccaaacgg aaaaaattaa tctttgatgt
      841 gattgtgatt gacccaccaa gctttgctag aaataaaaaa caaactttct ctgtgagcag
      901 ggactaccac aaattaatca cagaggcctt ggacatattg agtcctaagg gaactattat
      961 agcttcaaca aatgctgcta atatgactgt tagccagttc aaaaagcaaa ttatcaaagg
     1021 atttggaagt cgtcgtcctg agtctatgac tctccagcag cttccgagtg actttactat
     1081 caataaagca gatgaaagaa gtaactattt aaaggtattt actataaagg tacgagaatg
     1141 agaattgtag caccagtcat gccaagacat tttgacgagg ctcaagccat tgatatttct
     1201 aaatatgaag atgttaattt aattgaatgg cgagcagact ttcttcccaa ggatgagatt
     1261 gtcgcagtag caccagctat ttttgaaaaa tttgccggaa aagaaattat ctttaccctt
     1321 cggaccgttc aagaaggggg gaatattacc ctttcaagtc aggagtatgt tgatattatc
     1381 aaagaaatca atgctattta taatccagac tatattgact ttgagtattt tacgcacaag
     1441 tcagtatttc aagaaatgct tgattttcca aatcttattt tgtcttatca caactttgaa
     1501 gagactcctg aaaatttaat ggaagctttt tcagaaatga ccaagttggc accgcgtgtg
     1561 gttaaaattg ctgtgatgcc ccagagtgaa caagatgttc tagatttgat gaactatacc
     1621 agaggcttta agacgctcaa tcctgagcaa gaatttgcaa ctatatctat ggggaaatta
     1681 ggaagattgt ctcgttttgc gggagatgtc attggctctt cctggacata cgtttcatta
     1741 gatcatgtta gcggtccagg tcaagtgact ctcaatgata tgaaacgtat tattgaggtc
     1801 ttagaaatgg atatctctaa ctagtgaatg gtctaaaaat attatttcta caatagttaa
     1861 gaaatgatgt ttttagatta atgtttttaa aataagtgga accaaaaagg agaaaaattg
     1921 cgttatttaa cagcaggaga atctcatggg ccatccttaa cagctattat tgaaggtata
     1981 ccagcaggat taactcttca tccagcggat attgatcacg aattacagcg acgtcaagga
     2041 ggttatggcc gtggtgccag aatgtctatt gagactgatc gggttcaaat atcctcagga
     2101 gttcgtcatg gcaaaacaac aggggccccc attaccttaa cggtaattaa taaggaccac
     2161 caaaaatggc tagatgtcat ggctgtagga gacattgaag agactctcaa gttaaagcgt
     2221 cgtgttaagc atcctagacc aggacatgcg gatttggtag gaggtattaa atatcatttt
     2281 aacgatttaa gagatgcttt agagcgttcc tcggctagag aaacaacgat gagagtggct
     2341 gtaggcgctg ttgctaaacg tatcttagct gaacttggaa ttgatatgtt acatcatatc
     2401 ttaatatttg gtggtataac gatcacaata ccttctaagc tctcttttag agagttgcaa
     2461 gaaagggctc tccattcaga attatctatt gttaatccaa agcaagaaga agaaattaaa
     2521 acgtatattg ataagataaa aaaagaaggg gatactattg gtggtattat cgaaacgata
     2581 gttcaagggg tgccagcagg tcttggatct tatgtccaat gggataaaaa attagatgcc
     2641 aagctggctc aagcagttct ttccattaat gcttttaaag gggtggaatt tggagttggg
     2701 tttgatatgg gattccaaaa gggctctcag gtaatggatg aaatcacctg gacacctacc
     2761 caaggctatg gtcgtcaaac aaaccactta ggtggctttg aaggtggcat gaccacagga
     2821 caacctcttg ttgttaaagg ggttatgaag cccattccta ctttgtataa accactcatg
     2881 tcggtagata ttgatagtca tgaaccttat aaagcaacgg tggaacgctc tgatccgacg
     2941 gccttaccag ctgcaggggt tatcatggaa aatgtggtgg cgacggtgct tgccaaagag
     3001 attttagaga ctttttcttc tactaccatg tctgaattgc aaaaagcttt ttcggactat
     3061 cgtgcctacg tcaagcaatt ttagatagcg agatactggc ttttatggta tcatacaggt
     3121 attaatgaac aaaaggagac tgtcatgtca caagaaattt atgactatgc taatcaactt
     3181 gaaagagcag ttcgtgctct gccagaatac caaaaagtgt tagaagtaaa agaggccatt
     3241 caagcagacg ctagtgctag cgaactgttt gatgagtttg tcgctatgca agaaaaaatc
     3301 caagggatga tgcaatcagg ccaaatgcca acggctgaag aacaaacaag cattcaagaa
     3361 cttagccaaa agattgaagc taatgaccag ctaaaagctt attttgaagc gcagcaggcc
     3421 ttatctgttt acatgagtga tattgagcgt attgtatttg ctccgttgaa agatttagtc
     3481 aagtaagcca attaagatag gaaaaaaaca gattgctggc agctcgtcag gatctgtttt
     3541 ttagtgttta ttttctttgt atcagaaagt tgagcctctt tcttatttgt gatatagtca
     3601 aataaagtga ccaaaatagc aggccagtag tggctttaat gaaggcaagt tgtctgctaa
     3661 ctgactatgc taaaacatca gtattagaaa gtaaaaggtg ataaaaatgg ttattcctta
     3721 tgattatatt gttattggtg gagggagtgc aggtattgct tctgcgaaca gggcagccat
     3781 gcatggggcc aaagtattgt tagctgaagg taaaaagatt gggggaacct gtgttaacct
     3841 aggctgcgtt cctaaaaaag tcatgtggta tggcgctcaa gtagcagata ttttagggac
     3901 ttacgctaag gattatggat ttgactttaa agagaaagca tttgatttta aacaattgaa
     3961 agcaaatcgt caagcttata ttgatcggat tcatgcttct tatgagcgag gctttgagca
     4021 gaatggtgtt gaccgtattt atgattatgc tgttttcaaa gatgctcata cggtagaaat
     4081 tgcagggcag ctttataccg caccgcatat tttgattgcc acaggaggac atcctgtttt
     4141 tccagatatt gagggggcac aatacggtat cagctcggac ggcttttttg ccttagatga
     4201 ggtaccaaaa cgtacggctg tggttggggc aggctatatt gctgtggaac ttgccggtgt
     4261 tttgcatgct ttggggtcga agacggattt gtttatccgt cacgatcgac ctttaagaag
     4321 ttttgacaaa gccattgtgg atgttttagt tgaggaaatg gcagttggtg gtccttgctt
     4381 acactctcat tcagaagtgg caaaggttgt caaaaatact gatgagtcct tgacccttta
     4441 cctcaaagat ggccaagaag ttgaggttga ccagctcatt tgggctatcg gtcgcaagcc
     4501 taatctagaa ggttttggtc ttgacaaaac tggagtgacg ttaaatgata aaggttatat
     4561 tgagacagat gcctatgaaa acacgtctgt caaaggtatt tatgccgtgg gagatgttaa
     4621 tgggaaactg gctttaactc cagttgctgt ggcagctgga cgtcgcctat cagagcgtct
     4681 tttcaatggc aaaatagacg agaaattgga ctaccaaaac gttgctactg tgatttttag
     4741 tcaccctgtt attggctctg ttggcttgtc agaagaagca gcagtcaaac agtatgggca
     4801 agaagcagtt aaaacatatc aatcacgttt tacgtctatg tttactgcta tcactaacca
     4861 tcgccaacct tgtctgatga agttggtaac agtcggagat accgaaaaaa tagttggtct
     4921 tcacggaatc ggctatgggg ttgatgaaat gattcagggc tttgcagtag ccatcaaaat
     4981 gggagcaacc aaggcggatt ttgataacac cgttgctatt cacccaactg gctcagaaga
     5041 atttgtcacc atgcgctaaa aaatgtagcc taaggcaata aaaaatgatg ttaacagttt
     5101 ttgaggaaag tcttctaaac tgctagcatc gttttttgtt aggtgattag gggaatatgt
     5161 ttttaaagat atttgcgttg ctcagacaat attgccttac ctcggagata aaataaagtg
     5221 accctgtaac aacaaagagt tcatcagatg ttacggaacc ttgtaaccag tctctgtaat
     5281 cttttacctg tgggtattta tcaggataat cctctaaaag atttgcttca gggaaatcaa
     5341 aagtcgtgac agatacttca aaagtatcta gttgagccag caagtcggct aaaggcttac
     5401 gtttgagacc tgcaaagaga atatgaatag gacgtttggg aaattcttct tgcagtagag
     5461 actttaattt agcaatggaa tctggattgt gagcgccgtc taatagaaga ttaggttgaa
     5521 taaattcgga ccggccaggc caagttgttg cctcaattcc tttttgaatc gtttttggag
     5581 atattttagg aaaggatttt ctaagtaatt gagctgtcat aatggctaaa caggcattcg
     5641 ctttttgatg ttgacctaat agtttgagac ggagtttggt taaattcaag ttatcgtgtt
     5701 gaaaggaaaa cgtcttttct gaaggattga gcaaaaaatc ttttcctaat tgatataagc
     5761 gtgaaccggc tttttgggta acttgttgaa agacttgact agcctcctgc tcaagttgac
     5821 cgataataac gggttcttta gctttgataa cttctgcttt ttggtgagca atttctgcta
     5881 ggctataacc taaacgttct tggtgatcaa aactaataga agggcatacg acggccagag
     5941 catgaaaaac attggttgcg tcggttttcc caccaatccc tgcctcaata atggcaatat
     6001 caacaggttt aagattggca aagtagcaaa acattatgag cgtcactaac tcaaactcgg
     6061 taggtctatc ccaatttgtt tcaagggaca ttttagtgag aatgggtcta atcacgctca
     6121 cacattgcgc caattctagg tctgaaatgg gctggccatt aaggcaaatc cgatcgtgaa
     6181 aagagataat aaaaggagat gtaaaggttc cgacctgata accagaagtt gacaggatat
     6241 gctgtaagta ggctgtcaca gagcccttgc cgttagttcc aacaacgtga atagcaggga
     6301 atttgtcttg tggccggcct agtgcctcaa gtaaccaagc cattctggcc aaatcggtct
     6361 tgcgaccatt agccttaaag gtatgaatcc aggaaatgct atcataggta gtcattacta
     6421 tttcttgtcc ttctaacaat gcttttaagg tttcgtagga agaccagtat tagcatcttc
     6481 agctccagtt gcattaggaa gttgcgtccc ttcagtggtt gatggtgtct caggagctgt
     6541 aggagtagtc tcgttgtgag aaggtgcggt agaagatgac ggaagagttg tcttattatc
     6601 atctgtggtt tctgaagtac ctgtatggtt ttgattactc tgagaagact ctttttcaat
     6661 aatcttgaca atggtattac tcgattcttt gggtgtatca ttagaggtct tatctggtac
     6721 aggctgcagt gctcttgaaa tggtaatggt tgccacgatg atactcaaaa tactaccaat
     6781 aagtgcaatg gatttttgga aagctgtaaa acctgtttta atatgctcgg tagggacacc
     6841 tcctgattta cgaggttttt gttgacggga ataacgtgat gacatatttt tctcctttaa
     6901 aatcatcgta atgccaagat taaggaggag taaacagaag tcctagctcc tctttaacac
     6961 ttcatctatc agtataatct agaaaaaaag tgaagtcaac ggtttacctt atgtctagga
     7021 caaggaagtc ctttgggctt attgtaatac gaatattctt gatttcattt tagctatttt
     7081 gtgatagaat aaagtattga gtaaaaatga aggtgacaca tgatttattt tgataatgca
     7141 gccacaacca taccttatgg agaggctctt aaaacttacc aagaagtagc aacaaaaata
     7201 tatggcaatc cctcaagtct gcaccaatta gggacaaatg cgtctcgcat tttagaagct
     7261 tcccgtaaac agattgctgg tttgttgggt gttaagtcag aagaaatctt ttttacgtct
     7321 ggtgggactg aaagtgctaa ttgggctatt aagggaattg cttttgaaaa aactgctttt
     7381 ggcaaacata ttattatctc agccattgaa caccctgccg tgagtgaaag tgtcaaatgg
     7441 cttctcacac aaggattcga agtttcttat gctccagtga caacacaggg agttgttgat
     7501 gtgaatgctt tagctgagct gattagacca gacaccatct taatctcgat tatggctgtt
     7561 aataatgaaa tgggagctat ccaaccgatt agagccattt caaacctatt ggctaaccaa
     7621 ccaacgatca cctttcacgt tgatgctgtt caagccattg gtaaaatacc actctgtgat
     7681 tatatgacta atcgtgtgga tttggcttct ttttcagggc acaaatttca tagtgttcgt
     7741 ggtgttggct tcctttataa aaaagcaggc aagcgactca attctctctt gtcaggcggc
     7801 ggccaagagc aggagttacg ttcaaccact gaaaatgttg caggaattgc tagcatggcc
     7861 aaagcattaa gaatagtcac tgaaaaacaa gtgagcgtct tacctaaact aacagcgatg
     7921 cgagatgtga tttacaaagc tttgtccgct tacccagatg tgacagtatt ttcagctcaa
     7981 gaaggctttg cgcccaatat tttgaccttt gggattagag gggttcgagg agaagttatt
     8041 gtccacgcct ttgaaaaata tgagatttat atttcgacca caagtgcatg ttcgtccaaa
     8101 gcaggtaagc cagcaggaag cctagtggct atggggattc ctgtaaaaac tgcccagaca
     8161 gccgttcgta ttagtctaga cgatgacaac gatatgggac aagtagagca gtttttgacc
     8221 atattcaaac agatttatga taaaacacag aaagttaggt aagattaggt aagatggact
     8281 attcagaaat tatggttcgc catggtgaac tgtcaactaa agggaagaat cgcatgcgat
     8341 tcattaacaa acttaaaaac aatattcaag acgtactggc tcctttccca gccattgctg
     8401 tccgttcaga tcgtgatagg acccatgtgt ctctaaatgg cacagattat cagcctattg
     8461 tagaagcttt aaagctggtg tttggtgttc aagctctatc tcctgtttat aaacttgaaa
     8521 aaagtgtccc tcttttggta acagctgttc aagatatcat gacttctctt tatcgtgatg
     8581 gactgacgtt taagattgcc actaagcgta gtgatcacgc gtttgaattg gatagtcgtg
     8641 agcttaacag tcttcttggt ggagctgttt ttgaggtttt accaaatatc caagcccaga
     8701 tgaaacatcc cgatgtgact ctcaaagtcg aaattcgtga tgaagcagct tacatttctt
     8761 atgaagagat taagggagca ggcgggttac cagtaggaac gtcagggaaa gggatgctga
     8821 tgttatcggg cggtattgat tcaccagtag ctgggtattt agcccttaaa cgtggcctcg
     8881 atattgaagt tgttcatttt gctagccctc cgtacaccag tccaggtgcc ttggctaaag
     8941 cccaagacct tactcgtcgg ttaactcgtt ttggtggaaa tatccaattt atcgaggttc
     9001 cttttacaga aattcaagaa gaaattaaaa ataaggcacc agaggcttac cttatgacat
     9061 taacccgccg ctttatgatg cgcatcacag atgccattcg tgagcaacgt aagggtcttg
     9121 ttattgttaa cggtgagagc ctaggtcagg ttgctagtca aacccttgaa agcatgcagg
     9181 ccattaatgc ggtaacatca accccaatta ttagaccagt cgtgacaatg gataaacttg
     9241 aaattatcga gatggctcag gcgattgata cttttgacat ttctattcaa ccgttcgaag
     9301 attgctgtac tatttttgca ccagaccgtc ctaaaaccaa ccctaaacta ggtaatgctg
     9361 aaaaatatga agaacgcttt gatattgatg gtcttgtcca gcgtgctgtg tcaggaattg
     9421 ttgtcacaaa aatcacacct gaaatcgtca atgatgaggt tgaaaatctc attgatgctt
     9481 tactttaaaa gaaaagatca agtgtaaatc ttttagtagt cagtaatgat actattgaaa
     9541 agcctctata agggcttttt tgctgcaatg aaggaggaaa attttgaggc aagatgttat
     9601 aatagagaaa aaggagggtg tgtcttgatt aaaactatgc aatacaaaaa aacgatggca
     9661 acagttgttg ctcttatcgt cgcacttttg ctatttggct tgatttatga tttacttggg
     9721 gttcaaaaaa ataagctagc agctcaaaaa tctgctcagc caaaggtcaa aacagcgcgt
     9781 gttgtagcta atggcgacat tttaattcat gatattctct acatgagtgc tagaaaagct
     9841 gacgatacct atgatttcac tccttatttt gaatatgtta aggactggat tagcggtgct
     9901 gacttagcta ttggagatta tgaagggacc attagcccag attatccctt agcaggctat
     9961 cccttattca atgctccaga agagattgca ggtgctctga aaaatactgg ctatgatgta
    10021 gtcgatttag cccataatca tatcttagat tcccaattag acggtgccct taacactaaa
    10081 aaggtttttc atcaattagg tatagacagt attggcatct atgacaagga tcgttcaaaa
    10141 gaatccttct taattaaaaa tgtcaatggt atcaaaattg caattttagg ttattcttat
    10201 ggttataacg gcatggaggc cacacttagc caagaagact atgagaaaca catgtctgat
    10261 ttagatgaag ctaagataaa aaaagaactt cagctagctg aaaaaaaggc tgacgtgacc
    10321 attgtcatgc cacaaatggg aacagaatat gccttagaac cgacagcaga gcaaaaagaa
    10381 ctttaccaca aaatgattga ttggggagct gatgtcgtcc taggaggcca tccgcatgtt
    10441 attgaacctt cagagacagt tataaaaggt aggcaaaaga aattcattat ttactctatg
    10501 ggaaatttta tttcaaatca gcggcttgaa accgtagatg atatctggac tgagcgtggc
    10561 ctattgatgg accttacttt tgagaaaaaa gataacaaaa caaaaattaa aacagttgag
    10621 gcccatccaa ccatggtttt agccaaaggt aaaggcattg tgggtaaaga aggttttgaa
    10681 ctatacaatt atcgaacaat ggttttagaa gattttatca aaggtggaaa ataccacgac
    10741 aagattgatg aggaaaccaa agcaaaagta gcacttgcct atcaggaaat taatgattta
    10801 gttaacctga aatggtaatg tttggtggtt tagcatctaa cgataaaaaa tagagattaa
    10861 acttaatttt tccttgataa aaagcagtta tggtgctaaa atagtaacgt tgactaaatg
    10921 cacatcctgt gcaaccgcac gaaaatcgtt gtcaagtaga ccaagtctca cgattccagg
    10981 cgagtcttca cagagggaaa cctcaactaa aaattttata ggaggtgcat catgagcaca
    11041 tacgcaatca tcaaaactgg tggaaaacaa gttaaagttg aagtaggtca agcaatctac
    11101 gttgagaaaa ttgacgctga agctggcgca gaagtcactt ttaacgaagt tgttcttgta
    11161 ggtggtgaca aaactgtagt tggtactcca gttgttgaag gagctactgt cgttggaact
    11221 gttgaaaaac aaggaaaaca aaagaaagtt gtaactttca aatacaaacc taaaaaaggt
    11281 agccaccgta aacaaggtca tcgtcaacct tacactaaag ttgtcatcaa cgcaatcaac
    11341 gcttaattta ctagcttatg attaaagcaa tttttactcg ccaaaaaaat ggtcaactga
    11401 gcagtgttac actgacaggt catgctggta gtggtaaaca tggctttgat attgtttgtg
    11461 cctctgttag tactctagcc attaactttg ttaattctct tgaggtgtta gcagattgcc
    11521 aagcattagt agatcttaat gatgttgaag gtgggtatat ggctattaca ataccaccac
    11581 atgacaacaa ggaggaagtt caattattat ttgaatcttt tcttctagga atgactagtt
    11641 tggcgaagga ttcttcgaaa tttgtcaaca ctcaggtcat ctaaatttaa tttaagagag
    11701 gaaacaacat tatgttaaaa atgaatcttg ctaacttgca acttttcgcc cacaaaaaag
    11761 gtggaggttc tacatcaaac ggacgtgact cacaagctaa acgccttggt gctaaagctg
    11821 ctgacggtca aactgtttca ggtggatcaa tcctttaccg tcaacgtgga actcatatct
    11881 acccaggtgt aaacgtaggc cgtggtggag atgacacact ttttgctaaa gttgaaggtg
    11941 ttgtacgttt cgaacgtaaa ggacgcgata aaaaacaagt ttctgtttac ccagtagcta
    12001 aataattgtt taacatcgca ttatataagg ctttccaggt gtctggaaag ccgatttttt
    12061 tattttgcta ctcatttgct acccatattc taaaagccga tgtaggaaga gagcttgtca
    12121 gcagttttat cttttgagga tttagtaaca tgagcgtaga tattcatggt agtttggata
    12181 gtttcacgac caagtgtatt ggattttctt ctatcctact aaagattgta gttgcttatt
    12241 tagagcaata gttctaattg taaaaagtca gcataataaa acaatatcat aagatgttgt
    12301 tataacgggc tttatggtat aattaaggat actcatttta ggaaggaaag caatgaatat
    12361 tcaacaatta cgctatgtgg tagccatcgc taataatgga acttttcgag aagctgcctc
    12421 taaattgttt gtcagtcagc ctagcttatc agtttctatc aaagatttag aggcggaatt
    12481 agggtttcaa atttttaatc ggactacttc aggaacagtc ttgacaagtc aaggactagt
    12541 tttttatgag aaagctttag aagtagtcaa atcttttgat tcttttgaaa aaaccttttc
    12601 tcaagctgat ctggatcaaa atgaattttc tattgctagc caacattatg actttttgcc
    12661 acctcttatt acagcttttt cgcaacaata cgatggtcat cgtgtctttc gtatctttga
    12721 atcaacaact attcaaattt tagatgaagt tgctcaagga aacagtgaaa ttggtattat
    12781 ttacttgaat gtagacaatc aaaaaggtct ctttcagcgg atggataagc tgggcttaga
    12841 atatgtttct ctaattcctt ttactactca tatttatctt tcaaaaacgc atccattggc
    12901 taatcgcgaa gcgctttatt tgaacgatat tcaaggatta cctgcggtaa ggtttaccca
    12961 agaaagggac gagtatttgt attattctga aaattttgtg gatactagtg aatgccctcg
    13021 tatttataat gtgtcagata gggcaacctt gaacggtatt ttagagagaa ccaatgcctt
    13081 tgcgacagga tcaggttttc tcgatcatcg gagtgttaat gggattaaag tgatacctct
    13141 agctgatcat attgacaatc aaatgattta tgtcaaacga aaagataaaa acctttctgt
    13201 tgctggggcc acttttgtga ctattttaaa agactatttt gataaaagaa ggaaggcctt
    13261 aacatgaaaa aacgattgtt tgtgcttagc ttgatcctcc ttgtagcttt ggatcaactt
    13321 agtaaatttt ggattgtttc tcatatagcg cttggagaag tgaaaccctt tatcccaggt
    13381 atcgtcagct tgacttactt gcaaaacaat ggggctgcct tttccatatt gcaggaccag
    13441 caatggttct ttgttgtcat aacggtttta gttatcggtt atgctattta ttaccttgct
    13501 actcatcccc atttaaatat ctggaagcaa ttagctctct tgcttattat ttctggtgga
    13561 atcgggaatt ttattgatcg tttgcgttta gcttacgtga ttgatatggt tcatttagac
    13621 tttgtggatt ttgccatttt taatgtggca gattcatacc ttaccgttgg tgtcatattg
    13681 ttagtgatat gtttatggaa agaagaggat tatggaaatt aatgtgataa catcggggca
    13741 acgcttggat aaggcactag ctgatttaag tcccctgtca cgtggtcaag ccaatgacca
    13801 aattaagcaa ggccttgttt tagttaatgg tcagcaaaaa aaggctaaat atacggttca
    13861 agcaggagat gtgatttgtt ttgaactccc taaagaagaa gtcttagagt accaagctca
    13921 gaatattccc ttggacatta tctatgaaga tgatgctctc gccattatta acaagccaca
    13981 gggaatggtg gttcaccctt cggcaggaca cccttcagga acaatggtta atgccttgat
    14041 gtatcatatc aaggatttgt cctcaatcaa tggtgtggtt cgtccaggaa ttgttcatcg
    14101 gattgataag gacacctcag gtctcttaat ggtagctaaa acagatgcag ctcatcaagc
    14161 cttggcagaa gaattaaagg ctaaaaaatc tctcagaaaa tacctcgcca ttgtccatgg
    14221 aaacctaccg aatgatcgcg ggatgattga agctcctata ggtcgtagcg aaaaggaccg
    14281 taaaaaacag gctgttacag caaaaggcaa agaagcagtg acacgtttta cagtgctaga
    14341 acgttttggc gattacagtc tagtggaatt acaactggaa actggtcgaa cgcaccaaat
    14401 tcgtgttcat atggcctata ttggtcatcc tgttgctggg gaccctttat atggaccacg
    14461 taagacacta tcaggtcatg gccaatttct tcatgcaaaa acattgggat taacgcatcc
    14521 tatgacagga aaagaaatga tatttactgt tgaagctccc gaaatttttc aaaaggtgtt
    14581 aaagctgcta agaaaaaaat aaacagcgag gagtagccat tatttttagt cttatatctt
    14641 tgtgcaaagt ttttaacatt ataaaaaata ctaaaaagca tttacgataa gccaggaaat
    14701 atgagaagtc ttttatgtta ttgggatatg caacatatct gttagagatc tttatttaaa
    14761 ctccttaaag aaaagagata ttccaaatag atgctaggta ttgtcttttt tacttgtttt
    14821 tcttttcttt ttttgctata ctgattgaaa taaaatattc ctttaaaaca gtcctgtgag
    14881 gctgtcaagg agacggatta aaaacatgca ccatgatact taattgtgct atattttgct
    14941 gaatctcctt gtttccaagg agatcttttt atttgaattt ttagaggagg tttcaacatg
    15001 aaaactaagg aaattgttga tgacgtgacc atgaaacgcg ccattacccg tattacttat
    15061 gaaattattg aacgtaataa acaattagac aatgtggttt tggcaggcat caaaacgaga
    15121 ggtgtttttc tagctcgtcg cattcaagaa agactgcatc aattagaagg gttggattta
    15181 ccaattggtg agttagacat caagcctttt agagatgaca tgagagttga ggaagacaca
    15241 actctcatgt cagtagatat tacaggcaag gatgtgattt tgattgatga tgtgctttat
    15301 actggtcgta ccatccgcgc agccatcgat aacttagtga gtttaggtcg accagcccgt
    15361 gttagtctag ctgttttggt ggatcgtggc catcgggaat taccgattcg cgcggattac
    15421 gttgggaaaa atattccaac aagcagtgta gaagaaattg ttgttgaggt tgtcgaagtc
    15481 gatggccgtg atcgtgttag cattattgac ccaacataag aaagaggttt tactgtgaaa
    15541 gatgtcattt atgatgtgga agaagtgcca aaggcaggta tgttagttgg tttgtccttt
    15601 cagcacttat ttgctatgtt tggtgcgact gttctggttc ccattctagt tggaattgac
    15661 ccatcagttg ctttgttatc tagtggttta ggaacccttg cccacttatc agtgaccaaa
    15721 tttaaaattc cagcctacat gggctcaagt tttgcttata tagcagctat gcagttactg
    15781 atgaagacaa atggtattgg tgctgtagct caaggggcta tgacaggagg tctcgtttac
    15841 ctgattgtag ctttgattgt taaagctatt ggcaatgatt ggattgataa catcttacca
    15901 ccgattgtgg ttggtccgat tgttatggtc attggtctaa gcctagcttc tacagctgtt
    15961 aatgatgtca tgctaaaaaa tgggaactat aatctgactt atcttgttat tgggttagtc
    16021 accttattat cagttatttt tttcaatatt tatggtaagg gaattgttgc tattgtaccg
    16081 cttttattag ggctattagt tggttatgtt gtagcccttt tagtgggtgt tctcaccggt
    16141 caagaaattg ttgattttac caatgtggct caggccaaat ggtttagtat cccatcagtg
    16201 gaaattcctt tcttaaccta cggggttaaa ttctacccaa gtgccatttt aactatggca
    16261 cccattgcct ttgttacaat gacagaacat tttggacaca ttatggtctt aaatagtttg
    16321 acaaaaagag attatttcaa ggatccagga cttgaaaaga ctttaactgg tgatggtttt
    16381 gcgcaaatca ttgccggctt cttaggggca cctccggtca cttcttatgg tgaaaatatc
    16441 ggtgtaatgg ctttgaataa aatattctcg gtttatgtta ttgcaggtgc cgcagtgatt
    16501 gccgctctcc tcagttttat cggtaaggta tcagccttaa ttcaatctat tccaacacca
    16561 gttattggag gtatatcagt tgccttgttt ggtgtaatag cttctagcgg tttgaaaatc
    16621 ttgattgaat ccaaagttga tatggataat aagaaaaact tattgattgc cagtgttatt
    16681 ttggtctctg ggattggagg attgatgctt caagtaaatg gtcttcaaat ttcaggtgtc
    16741 gctttttcaa cacttcttgg catcatctta tatcaggtac ttcctgaaaa ataggaagaa
    16801 ttgttgttag accacttaca tagtcatcag tcgttagtga taaaggggat aatcatgtca
    16861 gttgtaaata atcgcgttgc acttaccaat ttagtttcaa tggaagcatt aaccaccgaa
    16921 gaagttttag gtcttatcaa ccgtggttca gaatataagg ctggtaaggt tgttatttcg
    16981 gatcatcaaa aggatcttgt tgccaattta ttctttgaaa actccacccg aacccataag
    17041 tcttttgaag tggctgagaa gaaactcggc ttgacagttc ttgatttcaa tgctgatgca
    17101 agtgcggtta acaagggaga aagtttgtat gatactgtgt taaccatgag tgcacttgga
    17161 acagacatct gtgtgattcg tcacccagaa gatgattatt acaaggaatt agtagaaagt
    17221 ccaactatta cagcttccat tgtcaatgga ggagatggtt ctggacaaca cccgagtcaa
    17281 tgtttacttg acttattaac catctatgaa gaatttggac actttgaagg cttaaagatt
    17341 gcgatcgctg gtgacttaac tcactctagg gtggcaaagt ccaacatgca aatcctcaaa
    17401 agattaggag cagagcttta tttctatgga cctgaagaat ggtattcaga agcctttaat
    17461 gcttacggca cttatattgc tattgaccag attattaagg aattggatgt tcttatgttg
    17521 ctgcgtgtac agcacgaacg tcatgacggc catcagagtt tttcaaaaga aggttaccat
    17581 caagcgtttg gattgacaca ggaacgttac caacaattaa aagattctgc tattattatg
    17641 catccagctc cagttaatcg ggatgtggaa attgcagata gtttggtgga agctcctaaa
    17701 gcgagaattg tatctcagat ggctaatggt gtctttgttc gcatggctat tattgaagcc
    17761 attttgaatg gtagaaataa aaactcatga tgaaagatta aagcatgttt agaaggtagg
    17821 aaaaggtagg aaaatgacaa aacgattact tattttagaa gacggcacta tttttgaagg
    17881 agaacccttt ggtgctgata ttgatgtgac tggtgaaatt gtctttaata caggaatgac
    17941 aggctaccaa gaatccatca ctgaccaatc ctacaatggg caaattttaa cctttaccta
    18001 tcctttgatt ggaaattatg ggattaatcg agatgactat gagtccattt cacccacctg
    18061 taaaggggtt gttgtgtctg aagtcagtcg gttggcaagt aattggcgca agcaaatgac
    18121 gctagatgcg ttcttgaaaa taaaagggat tccagggatt tcgggaattg atacgagagc
    18181 tttgaccaaa attattcggc aacacggtac catgaaagct acgatggcag atgatggaga
    18241 tagtatccag catttaaaag atcaactgcg tgcaacagtc ttaccgacta acaccattga
    18301 acaagtgtca actaaaacag cttatcctgc accagggatc gggaaaaata ttgtattggt
    18361 tgattttggt ttaaaacatt ctattttaag agaattttct aaaagacaat gtaatatcac
    18421 cgttgtccct ttcaacatca ctgcagaaga agtgctccaa ctaaatccgg atggcttgat
    18481 gctatctaat ggcccaggaa acccagaaga tttgccagag gctttagaca tgattcgtgg
    18541 ggtacaaggt aagattccta tttttggtat ttgtatggga catcaactct ttagtctagc
    18601 aaatggtgcc aagacttgta aaatgacctt tggtcatcgt ggctttaacc atgccgttag
    18661 agaaattgca acgggaagaa ttgattttac cagtcaaaac catggttatg ccgttgaacg
    18721 tagtagtcta cctgatactt taatggttac gcatgaagac attaacgata agacggtcga
    18781 aggagtgaaa catagagatt ttccagcttt ttcagtccaa tttcaccctg atgcggctcc
    18841 aggacctcat gatgccagct acttatttga cgaatttttg gaaatgattg attcttggag
    18901 atgtacgagt aaatagtaaa tcagttgcaa tttcacgact atatcacctc ttgttactct
    18961 atttattaac atttacagtt gatttagtac cctatcaaaa atattattta atgttgctct
    19021 gtgaggcaac aaatagagaa aggaaggcaa ggagaacaca agtaaataat ttagtaaaaa
    19081 gttaggtttt caaagagata aagctcttat tgagaagtgc tgactttacc gcttcttgtg
    19141 gtattcttgg tatcattaat tatgccaaaa cgaaaagata ttcaaaaaat catggttatc
    19201 gggtctggcc cgattattat tggacaagct gctgaatttg attatgcagg gactcaggcc
    19261 tgtttggctc taaaagaaga aggctataag gtcatacttg ttaattcaaa tcctgcaacg
    19321 attatgacag ataaagaaat cgctgataag gtatatattg agcctttgac tcttgaattt
    19381 gttaatcgta tcattcgaaa agaaaggcca gatgccatac tgccaacctt aggtggtcaa
    19441 acgggcctca atatggcaat ggcattatct aaagctggta ttcttgatga tttagagatt
    19501 gaattgttag gtactaagtt atctgcgatt gatcaggcag aagacagaga ccttttcaaa
    19561 caattaatgc aagaactaga ccaacccatt ccagaatcta caattgttaa aacagttgat
    19621 gaagctgtta catttgctag agatatcggt tatccagtca ttgtgcgccc agcttttact
    19681 cttggtggaa ctggtggagg aatatgtagt agtgaagaag aactttgtga aattactgaa
    19741 aacggcctaa agttatcacc ggtcacacag tgtttgattg aacgctcaat tgctggcttc
    19801 aaagaaattg aatacgaagt aatgcgagat agtgctgata acgcgctggt tgtttgtaat
    19861 atggaaaact ttgatcccgt agggattcac acaggagatt ctattgtatt tgcaccaaca
    19921 cagacccttt ctgatattga aaatcaaatg ttacgtgatg ctagtttaaa aataattcga
    19981 gctctgaaaa ttgaaggtgg ctgtaacgtc cagttagcac tagatcctta tagtttcaaa
    20041 tattatgtta ttgaagtaaa tcctagagtg tctcgttcct ctgcccttgc ttcaaaagca
    20101 acaggttatc ccattgccaa attggctgca aagattgctg ttggcctaac acttgatgaa
    20161 atgattaacc ctatcacagg cactacttac gctatgtttg aacctgccct tgattacgtt
    20221 gttgctaaaa ttccgcgttt tccgtttgat aaatttgaac atggtgaacg ccaactggga
    20281 actcaaatga aagcgacagg tgaagtcatg gctattggcc gtaatttgga agagtcctta
    20341 ctaaaagcct gtcgttcttt agaaattggt gtttgccata atgagatgac aagtttaagt
    20401 aacattagcg atgaagagtt agtgactaaa gtgattaaag ctcaagatga tcgacttttt
    20461 tacttgtcag aagcaatacg acgaggttat agtatcgaag aacttgagag cttgaccaag
    20521 attgatttat ttttcttgga taaattactt catattgttg aaatagagca agaattacaa
    20581 atgcatgttg accatttgga aagcctcaaa aaagcaaagc gttatggatt ttcagatcaa
    20641 aaaattgcag aaatttggca aaaggatgaa agtgatatca gagcgatgag acattctcat
    20701 agcctgtatc ctgtctataa aatggtagat acttgtgcag ctgaatttga tgctaaaacc
    20761 ccttattttt attcaacata tgagttggaa aatgaatctg ttcagtcgaa taaagaatca
    20821 attttagttt taggttcagg ccctattcgt attggtcaag gggttgaatt tgactacgca
    20881 acggttcatt ctgttaaagc catccaaaaa gctggctatg aagccattat catgaattca
    20941 aatccggaga ctgtatctac agatttttcg gtatcagata aattatattt tgaaccgtta
    21001 acctttgaag acgtcatgaa tgtgatagat ttagagcagc ctaagggagt aatagttcag
    21061 tttggaggac aaactgctat taacttagca caagcacttt ctgaggcggg tgttacaata
    21121 ttaggaacac aagtagagga tttggatagg gctgaagaca gagatttatt tgaaaaggcg
    21181 ttgaaagagc ttggaatccc acaaccacaa ggtcaaacgg caactaatga agaagaagct
    21241 ttagaggcag ctaaaaaaat tggttttcca gtcttagtta gaccttctta cgtacttggt
    21301 ggccgggcta tggaaattgt tgaaaacaaa gaagatctta gagaatatat aagaacagcg
    21361 gttaaagcaa gtcctgaaca tcctatctta gtggactctt atattttcgg taaggagtgt
    21421 gaagtggatg ccatttcaga tggaaaatca gtcttaattc ctggtattat ggagcacatc
    21481 gaaagagcag gtgttcattc aggagattca atggcagttt atccgccaca gcaattatct
    21541 aagcaaattc aagaaacaat agctgagtat actaaacgtt tagccattgg gttaaattgt
    21601 attggtatga tgaatgttca atttgttatt aaaaatgaac aagtttatgt tattgaagtg
    21661 aatccacgcg ctagtcgtac cgtacctttc ttatcaaaag taacaggtat tccgatggct
    21721 cagattgcta ctaagttgat tttaggtcaa acattaaagg atctaggata tgaagatggt
    21781 ctttatcccc aaagtcaact ggtgcatatc aaagcgcctg tgttttcatt tacaaagttg
    21841 gcacaggttg atagtctttt aggtcctgaa atgaaatcaa ctggagaagt aatgggttcg
    21901 gatactagtc ttgaaaaagc actttataaa gcgtttgaag ccaataattc tcatttatca
    21961 gaatttggtc aaattgtctt tactatagca gatgatagta aggcagaagc tctaagtcta
    22021 gcaagacgat ttaaggcgat tggctatcaa attatggcta ctcaaggtac agcagcttac
    22081 tttgctgagc aaggcttaag cgcgtgttta gttggaaaaa ttggtgatgc tgccaatgac
    22141 atcccgacac tcgtgcgaca tggtcacgtt caggcaattg ttaatacagt tggaattaaa
    22201 cgcacagctg ataaagacgg acagatgatt agaagttcag ctattgaaca aggagttcct
    22261 ttatttacag ctttagatac tgcaaaagct atgttaacgg ttttagaaag cagatgcttt
    22321 aacatcgaag cgatataaaa attaaaaaat catttttaag aaaacttaaa aatgattttt
    22381 ttagattata atgacaaaag tttcagtaag ctattaattt gtcatagcat ataagtcatt
    22441 atcttgtggc ttgttttcga ctaagggcta agaatttctt gacaacaata taaaaaggtc
    22501 atatacttgt cttatacaaa tagtacaaaa ggggaggata gaaatgtcta aaagaggaaa
    22561 aattaaaata acaacgaaaa caaagcttat tacagctagt gttataacgc tagtattaat
    22621 tataactgga gtagtcttgt ggaaacaaca acaaaatacg ctaacagctg atatcgctaa
    22681 agaaccttac tctactgtta gtgtaactga agggagtatt gcttcttcga ctttactatc
    22741 aggtactgta aaggctttat cagaggaata tatttatttt gatgctaata aaggaaatga
    22801 tgcaactgtt acagttaaag taggtgatca ggtaacgcag ggccagcaat tagttcaata
    22861 taatacaaca acagctcagt cagcttatga tactgctgtt aggagtctta acaagattgg
    22921 ccgacaaatt aatcatctta aaacatacgg agttcctgct gttagtacag aaactaataa
    22981 agatgaagct accggtgaag agacgacaac aacagttcaa ccatcagctc agcaaaatgc
    23041 taattataaa cagcagctgc aagatttaaa tgatgcttat gcagacgcac aagcagaagt
    23101 aaataaagcg cagatagcgt taaatgatac agtagttatc agtagtgtct ctggaactgt
    23161 tgtggaagta aataatgata ttgatccttc ttcaaagaac agtcaaacac ttgttcacgt
    23221 agcaaccgaa ggacagcttc aggtgaaagg aacattgaca gagtatgatt tagcaaacgt
    23281 taaggttggt caatctgtaa aaattaagtc taaagtttat tctaatcaag aatggactgg
    23341 aaaaatatca tatgtttcaa actatccaac tgagtctaat gcaggttcaa caacgccagc
    23401 aggtagcact ggagcgggaa gttctacagg agctgcctat gattacaaga ttgatattat
    23461 aagtcctctc aaccagctta aacaaggttt cactgtttct gttgaggttg ttaatgaagc
    23521 taaacaggcc ttagttcctt taacggctgt tattaagaaa gataaaaaac actatgtttg
    23581 gacttatgat gatgctactg gcaaagccaa aaaagtagag gtgacacttg gaaacgcaga
    23641 tgcacaacaa caagaaattc ataaaggagt agctgttggt gacattgtta ttgccaatcc
    23701 agataaaaat atcaaaccgg ataaaaaact agaaggggtt atttcaatag gtaccaacac
    23761 aaaaccggaa aaagattctc aatcaaagaa taaaaaatca ggggtggata aatagtgtcg
    23821 catgaaaaaa aacaattaat gcaattatca aatattgtga agagctatca aaatggggat
    23881 caagttctta aagttttgaa aggtattaat ttaacagtat atgagggtga atttttagct
    23941 attatgggtc cgtctggctc gggaaaatca acactaatga atattattgg tttattagat
    24001 cggccaacat ccggagatta cacattacat aatactaaaa tagaaatcct taatgatcgt
    24061 gaattagcaa aagtacgaaa cgatgaaatc ggctttgtct ttcaacaatt ctttctgtta
    24121 gctaaattaa ctgcattaca aaatgttgag ttgcctctta tttatgctgg tgtaaacgtc
    24181 tcaaaaagac gtgaacaggc taagcaattt cttgaaaaag taggacttgg acgacgtatc
    24241 aaacatctac cgtcagaact gtcaggaggt caaaagcaaa gggtggctat cgcacgagct
    24301 ttagtaaatg acccatctat tattttagcg gatgaaccaa caggtgcact agatactaaa
    24361 acaggtcagc aaattatgga actcttgaca gagttaaaca aagaaggtaa aacaattatt
    24421 atggttactc atgaaccaga aattgctgat tttgcaactc ggaaaattat tattcgtgat
    24481 ggtgatatca caacggatac tacagctagt gttgttattg actaggagga aaaataatgg
    24541 aaaattggaa attcgctctt agctcaattt gggggcataa gatgcgctca atcctgacaa
    24601 tgttgggaat tatcatcggt gtagcagcag ttgtgattat tatggggttg ggaaatgcta
    24661 tgaaaaatag tgtaacaagc acattttcta gcaaacaaaa agatattcaa ctctattttc
    24721 aagaaaaagg agaagaagaa gacctgtatg ccggattgca cacgcatgaa aataatcacg
    24781 aagtgaagcc agagtggtta gaacaaattg ttaaagatat tgatggtatt gattcttatt
    24841 actttaccaa ttctgctact tctactattt cgtatgaaaa aaagaaagta gacaatgctt
    24901 cgatcatagg ggtaagtaaa gattatttta atataaaaaa ctatgatatc gtagctggtc
    24961 gtacactaac agataatgat tattctaatt tttcgcgtat cattctttta gatacagtat
    25021 tagccgatga cctatttggc gaaggtaatt ataagttagc tttaaataaa gtggtaagtt
    25081 tatctgataa agattattta gttattggtg tttataaaac tgatcagacg ccagtttctt
    25141 ttgatggatt atcaggcggc gctgtcatgg caaatactca ggtagcttca gagtttggca
    25201 ccaaagaaat aggatctatc tacattcatg tgaacgatat tcaaaacagt atgaacttag
    25261 gaaatcaagc agctgatatg ctaaccaaca tatcgcatat taaagatgga cagtacgctg
    25321 ttcctgataa tagcaaaatc gttgaagaaa tcaatagtca gttcagtatc atgacaacag
    25381 tcataggttc aattgcagcg atctctcttt tagtgggagg aattggtgtt atgaatatta
    25441 tgttggtatc tgtcacagag cgaactaggg aaattggttt acgtaaagca cttggtgcaa
    25501 cacgcctgaa aattttatca caatttttga ttgaatccgt tgttctaaca gttcttggag
    25561 gcttgatagg attattatta gctcaattaa gtgtaggggc tttaggaaat gcgatgacat
    25621 taaaaggagc ttgtatttct cttgatgtgg ccttaatagc agttttattt tctgcctcaa
    25681 taggtgtctt ttttggaatg ttgccagcta ataaagctag taagttagat ccaattgagg
    25741 cattacgtta tgaatagaat agttcgtatc aattaatcta tagacgctga ctagtttaac
    25801 gtctgattat atctagtttt tgtattagca cagtagttat atcattgaag tgttagtgca
    25861 ttttttgagg tgataatatc tagcaaagct atcattggta tgatgatgtg gatagcgtat
    25921 aagtgataca tcttttattt ctagctgaac ttcggttcgg ctaggaagtt gtcaggcaat
    25981 gagttgttta aaataaagga gattagttca atgacatttt tatctgattt gatatcatta
    26041 atgacaaaaa tcagattatc ttgggtaata aaggcgggta tttttcaatt attatttgta
    26101 acgattgcta atattgtctt atcagaattt ttctatttta tattagacgt tactggtcaa
    26161 tatcatttag ataaagacaa tgttgtgact tttttaaaaa atcctatagc acttgcttta
    26221 ttaggtgcct atttattttt attagctgct tttattcacc ttgagttttt tgctctatat
    26281 cgaattattg cggatcaaga aattagtttc tatcttttta gaaaacagtt ttcttattac
    26341 ctaagggggc tttggaaaac attttctggt taccaattat tacttttttt gctttatatc
    26401 ctactgacta ttccagtctt acatattggt ttatcttctg tgattactca aaagctttat
    26461 cttccagaat ttattgttgg ggaattatca aagataacta gcacaaagta cttgctttat
    26521 ggcagtctta ttcttgtgtt ttaccttaac ctaagattag tatatttttt accattgata
    26581 gcaatcaacc atcgtacggt tgctcaagca tggagagaga gttggcaaaa gactaaaaag
    26641 aaacatgtat tgttatggat gaaacttttt gcaatcaatg gtcttacgct tgtagtctta
    26701 tcgctagcta tttccatgat tcttattttt gttgatatgt ttaatcctaa ggggaataat
    26761 attattgttc agctgggagc tttgaccttt acatgggagc tcattttttt tactactatt
    26821 ttttttaaac tctgttcagc aatgatttta aaagaggcaa ttgaaccaca aaagcaatat
    26881 gatgagccaa gaagaagtaa taaggcatat gttgtaatct ttatcgtggt gacagtaggt
    26941 tttgcttatc aatctcttga acgtttaact ttttttgaca catctcactc taagacagtt
    27001 atcgcgcata gaggacttgt atcagcaggt gtagaaaatt ctctggaagc ccttgaaggt
    27061 gctaagaaag caggaagtga ttatgtagaa ctggatctaa tcttgactaa ggataatcac
    27121 tttgtggtgt ctcatgataa tcgattgaag cgtttagctg gagtaaataa gacgattcgc
    27181 aacttaacct taaaagaagt tgaacatcta acgagtcatc aaggacattt ttcagggcgt
    27241 tttgtttctt ttgacacttt ttatcaaaag gctaagaagt tgaatatgcc attacttatt
    27301 gaactcaagc caattggtac agaacctgga aattatgtcg atttgttttt agaaacttat
    27361 catcgacttg gtataagcaa agataataaa gtcatgtctt tagatttaga agtaatagaa
    27421 gctatcaaga aaaaaaatcc atcaattacg actggttata tcataccaat tcaatttggc
    27481 ttttttggag atgaatttgt tgatttctat gtcattgaag acttttctta tcggtcttat
    27541 ttgtcgtccc aagctttttg gaataataaa gaaatttacg tttggactat taatgatccc
    27601 aagcgcatag agcattatct cctaaagcct attcagggaa ttattacaga tcaaccagct
    27661 ttaactaatc aattgattaa agacttaaaa caagataatt cttattttag tcgattagtc
    27721 agaattatta gtagtcttta ttaaaggttt aaagaaagtg tcaagaaaaa aacttgacac
    27781 tttctttaaa ctgagttata ctgtttaaca taggaattta gcgtagctgt atttcttata
    27841 cattactaaa agaaaagaga ctatttaaaa atggcagtaa aaatccgttt aactcgtatg
    27901 ggttctaaga aaaaaccttt ctaccgtatt aatgttgcag attcacgtgc accacgtgat
    27961 ggtcgtttta tcgaaacagt tggaacatac aacccattag tggctgaaaa tcaaattact
    28021 attaaagagg atcgtgttct tgagtggtta tctaaaggag cgcagccttc tgataccgtt
    28081 cgtaacatct tgtctaaagc tggtgttatg gctaagttcc acgaccaaaa attctctaaa
    28141 taataacagc ctatggatac cattgaaaat cttattatcg ctattgtgaa acctttgatt
    28201 tcacaaccag ataatcttac cattaaaatt gaagatactc ctgacttttt agagtatcat
    28261 cttgacttgg atgctcaaga catcggtcgt gttatcggca aaaaaggtcg aactattact
    28321 gcgataagat cgattgtcta ctcggttcca acactaggaa aaaaagttcg cttagttatt
    28381 gatgagaaat aatcactaac ttgagatgga ttgaaaagct tgttgacttt aagtcaacaa
    28441 gctttttgaa tagcaaaaat cttaatattt ctgaaatgaa aagattagat ttttctgtct
    28501 ttaactaaaa agaagttaaa gaatggctta gctgattgcc tttataagag attatactgg
    28561 tttttgatag ctgctgtcat gtaaaatagc tacaattcat cttacgagat tgaccttagc
    28621 attgccagtg cagtctttat tttccaacct gctgtttgtt gtatgtttat agtttcctaa
    28681 aaaatgttct ctcagttttt tgggggacat tcctaaaatt aagtatactt aattttagga
    28741 atgtttatat tctttacatt ctgatgaaaa tacaaattat cctaacatga tgtattgaaa
    28801 ggagaaatag tttatgttag tatactgatt aagtgaagct gtaatgaggc ttatacgatc
    28861 aaaaaagtta gagtaacttt ataaaacagt ggtgttgaag caagtttagc ttcttctcag
    28921 aaatagatta tctataaaaa atcccaaaag tagtttgttt ccagttaatg aacttctttt
    28981 gggaaggctt ttttgctgat cgccacttca cttgtatatc gggaacattc acgctaagat
    29041 gtataagttg aatcgtttgt ctatggcttg atgaaaatta atcaaaagat aatgttcaac
    29101 tctataatta gtacaagcaa aatgagataa cttattcatt agtaagcata agatataaca
    29161 agagaaatta ccttaaaaca ggaagtacta gagtatttaa aataagtgat agacttggat
    29221 attattaggt cgactagtgt tcttttcaat aatttaatat cgttattatt agtatcagcc
    29281 aatcaaatgt gaataagttg gcttttagaa aggttttacc acaatgaaga aacatcttaa
    29341 aacagttgcc ttgaccctca ctacagtatc ggtagtcacc cacaatcagg aagtttttag
    29401 tttagtcaaa gagccgattc ttaaacaaac tcaagcttct tcatcgattt ctggcgctga
    29461 ctacgcagaa agtagcggta aaagcaagtt aaagattaat gaaacttctg gccctgttga
    29521 tgatacagtc actgacttat tttcggataa acgtactact cctgaaaaaa taaaagataa
    29581 tcttgctaaa ggtccgagag aacaagagtt aaaggcagta acagagaata cagaatcaga
    29641 aaagcagatc acttctggat ctcaactaga acaatcaaaa gagtctcttt ctttaaataa
    29701 aacagtgcca tcaacgtcta attgggagat ttgtgatttt attactaagg ggaataccct
    29761 tgttggtctt tcaaaatcag gtgttgaaaa gttatctcaa actgatcatc tcgtattgcc
    29821 tagtcaagca gcagatggaa ctcaattgat acaagtagct agttttgctt ttactccaga
    29881 taaaaagacg gcaattgcag aatataccag tagggctgga gaaaatgggg aaataagcca
    29941 actagatgtg gatggaaaag aaattattaa cgaaggtgag gtttttaatt cttatctact
    30001 aaagaaggta acaatcccaa ctggttataa acatattggt caagatgctt ttgtggacaa
    30061 taagaatatt gctgaggtta atcttcctga aagcctcgag actatttctg actatgcttt
    30121 tgctcaccta gctttgaaac agatcgattt gccagataat ttaaaagcga ttggagaatt
    30181 agcttttttt gataatcaaa ttacaggtaa actttctttg ccacgtcagt taatgcgatt
    30241 agcagaacgt gcttttaaat caaaccatat caaaacaatt gagtttagag gaaatagtct
    30301 aaaagtgata ggggaagcta gttttcaaga taatgatctg agtcaactaa tgctacctga
    30361 cggtcttgaa aaaatagaat cagaagcttt tacaggaaat ccaggagatg atcactacaa
    30421 taaccgtgtt gttttgtgga caaaatctgg aaaaaatcct tatggtcttg ctactgaaaa
    30481 tacctatgtt aatcctgata agtcactatg gcaggaaagt cctgagattg attatactaa
    30541 atggttagag gaagatttta cctatcaaaa aaatagtgtt acaggttttt caaataaagg
    30601 cttacaaaaa gtaaaacgta ataaaaactt agaaattcca aaacagcaca atggtgttac
    30661 tattactgaa attggtgata atgcttttcg caatgttgat tttcaaaata aaactttacg
    30721 taaatatgat ttggaagaag taaagcttcc ctcaactatt cggaaaatag gtgcttttgc
    30781 ttttcaatct aataacttga aatcttttga agcaagtgac gatttagaag agattaaaga
    30841 gggagccttt atgaataatc gtattgaaac cttggaatta aaagataaat tagttactat
    30901 tggtgatgcg gctttccata ttaatcatat ttatgccatt gttcttccag aatctgtaca
    30961 agaaataggg cgttcagcat ttcggcaaaa tggtgcaaat aatcttattt ttatgggaag
    31021 taaggttaag accttaggtg agatggcatt tttatcaaat agacttgaac atctggatct
    31081 ttctgagcaa aaacagttaa cagagattcc tgttcaagcc ttttcagata atgccttgaa
    31141 agaagtatta ttaccagcat cactgaaaac gattcgagaa gaagccttca aaaagaatca
    31201 tttaaaacaa ctggaagtgg catctgcctt gtcccatatt gcttttaatg ctttagatga
    31261 taatgatggt gatgaacaat ttgacaataa agtggttgtt aaaacgcatc ataattccta
    31321 cgcactagca gatggtgagc attttatcgt tgatccagat aagttatctt ctacaatggt
    31381 agacctcgaa aagattttaa aactaatcga aggtttagat tattctacat tacgtcagac
    31441 tactcaaact cagtttagag acatgactac tgcaggtaaa gcgttgttgt caaaatctaa
    31501 cctccgacaa ggagaaaaac aaaaattcct tcaagaagca caatttttcc ttggccgcgt
    31561 tgatttggat aaagccatag ctaaagctga gaaggcttta gtgaccaaga aggcaacaaa
    31621 gaatggtcag ttgcttgaaa gaagtattaa caaagcggta ttagcttata ataatagcgc
    31681 tattaaaaaa gctaatgtta agcgcttgga aaaagagtta gacttgctaa caggattagt
    31741 tgagggaaaa ggaccattag cgcaagctac aatggtacaa ggagtttatt tattaaatac
    31801 gcctttgcca ttgccagagt attatatcgg attgaacgtt tattttgaca agtctggaaa
    31861 attgatttat gcacttgata tgagtgatac tattggcaag ggacaaaaag acgcttatgg
    31921 taatcctata ttaaatgttg acgaggataa tgaaggttat catgccttgg cagttgccac
    31981 tttagctgat tatgaggggc tcgacatcaa aacaatttta aatagtaagc ttagtcaatt
    32041 aacatctatt cgtcaggtac cgactgcagc ctatcataga gccggtattt tccaagctat
    32101 ccaaaatgca gcggcagaag cagaacagtt attgcctaaa ccaggtacgc actctgagaa
    32161 atcaagctca agtgaatctg ctaactctaa agatagagca ttgcaatcaa acccaaaaac
    32221 gaatagagga cgacactctg caatattgcc taggacaggg tcaaaaggca gctttgtcta
    32281 tggaatctta ggttacacta gcgttgcttt actgtcacta ataactgcta taaaaaagaa
    32341 aaaatattaa attgatttaa ggagaaaaaa tgataacaca agaaatgaaa gatcttatta
    32401 ataaccaatt agcaatggtt gcgacggttg atgccaaagg tcaacccaat attggtccaa
    32461 aacgttctat gcgtctctgg gatgataaaa catttattta taatgaaaat acagatggtc
    32521 aaactcgtat taacattgaa gataatggga aaattgaaat tgcctttgtt gatcgtgagc
    32581 gccttttagg ttacaggttt gtaggaactg ctgaaattca aacagaaggt gcttattacg
    32641 aagcagcgaa aaaatgggca caaggacgca tgggggtacc aaaagcagtt ggtattattc
    32701 atgtcgagcg tatttttaat ttacaatctg gtgctaatgc aggtaaagaa ataaacagtg
    32761 aaagtaacta aaattaactg taacagtatt taggaccctt attttaaacg ctaaaaaaca
    32821 agcatactct tttttacagc atagtgacta tgttgtaaaa aggggtatgc ttattaggtg
    32881 ctcttaatat ttctagataa ctgcacctaa taagttttca atagacttat agcacattag
    32941 ttgacttcaa ttagttgact tcaattagtt gacttcaata ccagaaagag aagaacagtg
    33001 atgttggtgt tcgtttaaag aagtatcgat ttccacagtg actgagttta tattgtacct
    33061 ttgacaaatc agtctaatag attttttgca atgtttttca gtggtagatt ctttcaagca
    33121 gcaatgtata gttgctctat ggtcaatacc atccatcgac caaacattaa gctgattaac
    33181 agacactata tgaggaagtt ggctgagttc atggtgcaaa gcgcaatagt ctatcgaatc
    33241 aggaacacca tctaaaaaaa tgttagcggt tgctactaac tttggaagag ctttagataa
    33301 tataaaagaa gcaatggcaa ttgataataa aggatcaaga atgtaccaag gtttccattt
    33361 taagatcagt gacaatatga taatggctaa ccacccaagg atatcttcta aaaagtgaag
    33421 gcttaatatt tcttcatttt ttgtctggtt agagtgaatg atgaagctag caaatccatt
    33481 gattataatt gcaaaaatag ctaaaacgaa cataccgtca taattaacaa tagtaggatg
    33541 ccataatttt ggtatcgttt caatcattac taataatgac ccgctaataa gtattagatt
    33601 tgtcgttagt gctcctaaaa ggctaaatcg cttatagcct agtgaaaaat ttgaactctc
    33661 ttttttaaca gcctttcttt ctaagatagc tgagatacca atagcaatgg catctccaaa
    33721 atcgtggaca gcatctgcta aaatagcacc cgaaaagaat aatgtcccaa aaataaattc
    33781 aatgagggaa aaactaagat ttaatataaa aataatggtg acttttttac ttactggcat
    33841 aattttctcc ttttgttata ctggtaatat gtatagtaga attctttatt ctattatcta
    33901 aaagttaaaa tacaattact ataaccaaaa atgagcacct gttcaatagt gaacaacatt
    33961 tagaaagtgt gtgatatgac aaaagacaga caaatcaaaa aaacaaaaac agctatctat
    34021 agtgctttta ttgctttatt acaaaaaaaa gaatattcga aaataactgt tcgagatatg
    34081 attacacttg ctaatgtagg gagatcaacc ttttatgcac attatgaaag caaagaaatg
    34141 ttactaaaag aactctgtga agaacttttt catcatttgt ttaggcaaaa aagaaatgtg
    34201 acttttgagg actatttggt acatatttta aagcattttg aacaaaataa agacagcatt
    34261 gcgacgttgt tactttctaa tgatccctat tttttattaa gatttaaaaa cgaactagaa
    34321 catgatgttt accctaactt gcgctgcaag tatatcgaca aaacgactat tccagaagta
    34381 ttcctaaaac aatttgttct atctagtttt atagaaacct taaaatggtg gctccatcaa
    34441 aggcaaagga tgtctgcaaa tgaactatta aagtattatt tagagttcat aaaataatga
    34501 ctagtgagtc atcttgccaa attcaatttt ttaatacaga cggattttaa caatttagca
    34561 gagaaagaca aaactgtaag tgcaaaatag actataacgt gataaaataa taggtaattt
    34621 ggttctgaaa aagaagtgtc tatcaaactt tagaatcaag agaggtcgct aaagtgacgt
    34681 gagataaaga gttaacgatt taggagctac catggaatat tttaatgttg gaaaaattgt
    34741 caacacgcaa ggcctgcaag gagagatgcg cgtgttgtct gtcagtgatt ttgctgagga
    34801 acgctttaaa aaaggctcac aattagcttt atttgatgat aaagatcggt ttgttcaaga
    34861 agtgacaatt gttagtcacc gtaaacaaaa gcattttgat atcatcaaat ttaaagacat
    34921 gtatcatatt aatgctattg aaaagtacaa gggatacact ttaaaggtct caaaagacaa
    34981 tcaaggggat ttacaagaag gagaatttta ttaccatcag attattggca tggctgttta
    35041 tgaaaaggat gtccttattg gacatgttaa ggaaatcttg cagccaggtg ctaatgatgt
    35101 ttgggtagtg aaacgccaag gaaaacgaga cttgctctta ccatatattc ccccagtagt
    35161 tcttagcgta gatgttccta acaagcgcgt agatgttgaa ttgatggaag gcttagacga
    35221 tgaagattga tattttaacc ctttttcctg aaatgtttgc ccccctagaa cattccattg
    35281 taggcaaagc aaaagaaaaa ggattacttg acattcacta ccataacttt cgagattatg
    35341 ctgaaaaagc tcgtcatgtg gatgacgaac cctatggtgg gggccaaggc atgttattga
    35401 gagcgcagcc catttttgac accattgaac agattgaagc caaaaaacca aggattattc
    35461 ttttagatcc agcaggtaaa ccctttactc aggcttatgc tgaagaatta gctcttgagg
    35521 aagagttaat ttttatttgt ggtcattatg aaggttatga tgagcggatt aagaccttgg
    35581 tgacggatga aatttcatta ggtgactttg tattaacagg aggtgagttg gcggccatga
    35641 ctatagtgga tgcgaccgtc aggttaattc cacaggtact tgggaaagaa agtagccatc
    35701 aggacgattc tttttcatca ggacttttag aataccctca atacacaaga ccttatgatt
    35761 atcgtggtat gacagttcca gatgttctaa tgagtggtca tcacgaacgt attcgcttgt
    35821 ggcgtctaga agaaagtctc agaaaaacct atttgagaag gccagatttg ttagagcggt
    35881 acgatttttc cgaggaagag cgcaagctat tggataagat taaagaagca ttgggttaag
    35941 gagaagatta gtgaaagata aagcatatga tattacgatt attggtggtg gtccaatagg
    36001 tttatttgca gccttttatg caggtcttag gggcgtaaca gtaaagatta ttgagagttt
    36061 gtcagaactt ggtggacagc ctgccattct ttatcctgag aaaatgattt atgatattcc
    36121 agcttataca tctttaacag gtgttgagtt gacagaaaat ttaataaaac aattaagccg
    36181 ttttgaagat cgtacaacca tttgtttaaa agaagaagta ttaacctttg acaaggttaa
    36241 aggtggtttt tcgattagga ctaataaggc agagcatttt tcaaaagcta ttatcattgc
    36301 ttgtggaaat ggcgcttttg caccaagaac tttagggtta gaaagtgagg aaaactttgc
    36361 tgatcataac cttttttata atgttcacca gttggaccag tttgcgggac aaaaagttgt
    36421 gatttgtggt ggtggagatt cagcagttga ttgggctttg gctttagaag atattgctga
    36481 gagtgtgacg gttgtgcacc gtcgtgatgc tttcagagca catgaacaca gtgtggaatt
    36541 attgaaaaca tcaacggtaa acctcttaac accttatgtg ccaaaagcat tgaaaggaat
    36601 tggaaacctg gctgaaaaat tagttattca aaaagtgaaa gaagatgaag tgttagaact
    36661 tgaattggac agtcttattg ttagttttgg tttttcaact tctaataaga atttgaaaaa
    36721 ttggaatctc gactataagc gttcaagtat tactgtttca ccactttttc aaacaagtca
    36781 agaaggtatt tttgccattg gtgatgcagc cgcttataat gggaaagtgg atttgattgc
    36841 tactggtttt ggcgaagcac caacagcagt taatcaggcc attaactata tttatccaga
    36901 tcgagataac cgtgtggtgc attcaacctc tttaattgac taagggagtc ggaagtttca
    36961 agagcagtag caacagttaa tattcagttt gtcaggagag gacaaatggt ttttacctaa
    37021 gtcttcgtga caagttttat actttgtgat aaaatagtca ttgtgaaaaa agtgtgatgg
    37081 ttttcacaga ttaacacatt acaatgaaaa ggggtctatc atgacaacaa cagataaaga
    37141 gacatttagt tcttttatga ataaggtctt ggctggtaca gcgattgcta tcgttgtggc
    37201 actcattcca aatgctattt tagcgacttt cttaaaaccg cttttgccaa acatggcagc
    37261 tgctgaattt ttacacattg tgcaagtctt ccaattcttt acgccgatta tggctggttt
    37321 cttgattggg caacaattta agtttaatcc tatgcaacag ttggctgttg gtggagctgc
    37381 ttatatcggt tctggggctt gggcttatac agaagtcatt caaaaaggtg tggcgacagg
    37441 aacattccaa cttagaggta ttggggactt aatcaatatg atgattacag ctagccttgc
    37501 ggttttagct gtgaaatatt ttgggaatag atttggctct ttaaccatta tcttgttacc
    37561 tatcactata ggaactggcg taggttatat tggttggaaa tttttgcctt atgtgtctta
    37621 cgtgacaacc ctgatcggac aagggattaa ttcttttaca accttacaac ctattttaat
    37681 gtctatttta attgcagttg ctttctcgct tatcattgtt agtccgattt caactgttgc
    37741 aatcggttta gctattgggc ttaatggaat ggctgcggga gcagcttcta tgggaattgc
    37801 atcgacagca gcagtcttag tgtgggcgac gcttaaagtt aataaatctg gtgtaccaat
    37861 tgctatcgca cttggggcta tgaaaatgat gatgccaaac ttcttgaaac atcctatcat
    37921 ggctattccg atggtgttca ctgcagcaat tagctcatta acagtaccat tgtttaatct
    37981 tgttggaaca ccagcttcat ctggttttgg cttagttggt gcagtaggtc cgattgcttc
    38041 tttagcaggt ggtaactcaa tacttattat tatccttgct tggatcattg ttccgtttgc
    38101 ggttgctttt gcggcgcata aggtttctaa agatattcta aaactttata aagaagacat
    38161 tttcgtcttt gaaggctaat aggaggaaaa tatgttagtt tatattgctg gctcaggagc
    38221 catggggtgc cgttttggtt accaaatttc aaaaacaaat aacgatgtga ttttgttaga
    38281 taactgggaa gatcatatca atgccattaa agaaaacggg ttgattgtaa caggtgatgt
    38341 ggaagaaaca gttaagcttc ctattatgaa accgactgaa gccactcaag aagccgattt
    38401 gattatcttg tttacaaaag caatgcagtt gccacaaatg cttcaagaca ttaaaggcat
    38461 tattggaaaa gaaaccaaag tgctttgcct tttaaatggt cttggacacg aagacgttat
    38521 tcgtcagtac attccagagc acaacatttt gatgggggtc actgtctgga ctgctggtct
    38581 agaaggacca ggtcgtgctc atcttcaagg agttggtgct cttaacttac aaagtatgga
    38641 tccaaacaat caagatgcgg gacatcaagt agctgacttg ctaaataaag ctaacttaaa
    38701 tgcgacttat gatgagaatg ttgtgccaaa catctggcga aaagcttgcg tgaatggtac
    38761 catgaattcg acttgtgctc ttttagattg tacgattggc gaattatttg ccagtgaaga
    38821 tggtctcaaa atggtaaaag aaatcatcca tgagtttgtt atcgttggtc aagcagaagg
    38881 tgtcgaacta aacgaagaag aaatcacaca atatgtaatg gatacatctg ttaaagctgc
    38941 tcaccattac ccatcaatgc accaagacct tgtgcaaaat caccgattga ctgaaattga
    39001 ttttatcaat ggtgcagtca ataccaaagg tgaaaagctt ggtatcaata ctccatactg
    39061 ccgtatgatt acagaactag ttcacgctaa agaagcagtg ttgaacatcc aataaacgct
    39121 atcaaatcgt tatactcaat attatggcta aagctttaat attgagtttt ttgttatgct
    39181 gatagtattt ttcttaggcg tcattatttg tgagcctaga ttatgagtta ataaaagaaa
    39241 taataattgg tagaatttga tagattttga aaggttatgc ttgactttta gttataaaat
    39301 agtataataa ttgtaaacga tttcagttag gggtggttct atcttaaaat caaaacgaaa
    39361 acaattaatc atggcaaaga tcactgaaga aaactatgtt tctttagagg atttaatgca
    39421 attactcaac tcctctgagt ctactatccg tagagatcta ggagagttgg agcaagaagg
    39481 acggctacat cgtgttcatg gaggtgctga actttttcac tctttacaag aggaactttc
    39541 taaccaagaa aagtctgtca aaaacagtca tattaaaaaa gctattgcgc aaagagcctc
    39601 tcagcttatc tatgacaacg atgtgatctt tattgatgct gggacaacga ctgaattttt
    39661 attacctttt ttacaagcta aaaatttaac tgtagttact aattctattc atcatgctgc
    39721 tagattagtt gaactctcta ttgagacgat tattgtaggt ggttatgtca aacaaacgac
    39781 cgatgccagt attggtaatg tagctttgga acagattagg cagatgaatt ttgacaaggc
    39841 atttcttgga atgaatggtg ttgatgattc ttacctgacg actcctgata tggaagaagc
    39901 agttattaaa aaagcggttc tgtcaaatgc aaaattagct tatattttag tagatggcac
    39961 taaaattggt caggtatcgt ttgtaaaagt agctcctatt aatgatgtga ctattattac
    40021 attaggagga tcagcaagta ttcttaaaca aataaaggaa aaggcaaagg tgattgaatt
    40081 atgatttata ccgtgacctt aaacccttct attgacttta ttgtcagaat tgaccaaata
    40141 aatcttgggt cagtgaatcg catggcgagt gatgataagt ttgctggagg taaaggcatt
    40201 aatgtgagtc gtatcttgca acgtttagac attgctagca cggcgacagg gttcttgggt
    40261 ggttttacag gacgttttat cgaagaaagt ttgagtgcag aaggcgttaa aactgatttt
    40321 gtaaaaggtg atcaagatac tcgaatcaat gttaaaatca agtcacaaga agagaccgaa
    40381 ttaaatggtc aaggacctat cattagtcgg gaacaactag aggagttgaa aactaagctt
    40441 tcccagctaa cagcagagga tacagttgtc tttgcaggtt cagcgccagc taatcttggc
    40501 aatgctgttt ataaggaatt acttccttta gttaggcaaa gcggtgctca ggtggtttgt
    40561 gattttgaag gacagacttt aatagatgcg cttgcatata atcctctgtt ggttaaacct
    40621 aataatcatg aactagaagc tatttttggt acgattctga ctagtcttga tgatgttgaa
    40681 acctatgccc gtcgtctttt agagatgggt gctcaaaatg tcatcatttc aatggctggt
    40741 gatggtgctt tgctggttac taaagaagcg acttattttg ctaaaccgat taagggagaa
    40801 gttaaaaatt ctgtcggtgc tggtgattcg atggttgctg gctttacagg cgaatttgtg
    40861 aagagtcaaa atccaataga agccttaaaa tggggcgtgg cttgtggtac agcgacggct
    40921 ttctctgatg acttggcgac aattgcattt attaaggaaa catatcataa agttgaggta
    40981 gaaaaacgat gaaaattcaa gatttattga gaaaagatat tatgattctc gatttacagg
    41041 ctatttctaa agaagttgcc attgacgaga tgattactaa attagttgaa aaagatattg
    41101 tacatgattt tgatgtcttt aaaaagagta tcatgacacg tgaagaacaa acatcaacag
    41161 ggcttggtga tgggattgcc atgcctcatt ctaaaaatat tgtagtagat aaaccagcgg
    41221 tcttgtttgc gaaatcaaat aaaggtgtgg attataaggc tttagatggt caaccaacgg
    41281 atctcttctt tatgattgct gcgcctcaag gagcaaatga tactcacttg gctgcgctag
    41341 cagaattatc acaatacctt ttgaaagacg gctttgctga taaacttcgt gctgcagcga
    41401 caccagaagc agtcattgct gtttttgatg aagcgtcaac agctaaagaa gaagtggttg
    41461 ctccaacaag tggtcaagac tttatcgttg ctgttacagc ttgtccgaca ggaattgctc
    41521 acacttatat ggcagaagag gctttgaaaa aacaagctgc agaaatggga gtagctatta
    41581 aagttgaaac aaacggtgct tctggtgtgg ctaatcgttt aaccgctgaa gatattcaga
    41641 gagctaaagg agttattgtt gcagctgata aagcggttga aatggaccgt tttgatggta
    41701 aacaattcat tgctcgccct gttgcagatg gtatcaagaa gagtcaagaa ttgatttctt
    41761 tgattttgaa taatgaagga cacacttacc acgctaagaa cggaaagtct gaaacagcag
    41821 tatcatctga gaaaacaagc ttaggcggtg ctttctataa acacttgatg ggtggtgtct
    41881 ctcaaatgtt gccattcgtt attggtggcg ggattatgat tgctctagct ttcttgttgg
    41941 ataacatgct tggtgtgcca aaagaccaac taggcaatct tggatcttat catgaagtag
    42001 ctgctatttt catgaaaatt ggtggtgcag ccttctcctt catgttacca gtattagcgg
    42061 gttacattgc atactctatc gctgaaaaac caggtttggt tgctggtttt gtggcaggta
    42121 ccattgcctc aaatggtctt gcttttggta aggtaccatt tgcagcagga ggagaagtga
    42181 gcttgggctt aacgggcgtg ccatcaggtt tccttggggc gcttgtgggt ggtttccttg
    42241 ccggtggtgt tattcttgcc cttcgtaaat tgttggcagg cctaccacgt tctctagaag
    42301 gggttaaatc tatcctcctt tacccattac ttggcgtcct tgtcactggt ttcttgatgc
    42361 tttttgtcaa tattccaatg gcagctatta acacagccct taatgatttc ttacaaggtc
    42421 tttcaggaag ctctgctgtc cttatgggac ttcttgttgg tggaatgatg gctgttgaca
    42481 tgggtggtcc tgttaataag gcagcttatg tttttggtac aggaacttta gcagctactg
    42541 tcgcaaatgg cggttcagtc gttatggctg ctgttatggc aggtggtatg gtacctcctc
    42601 tagctgtttt tgtagccact ctcttgttta aagataaatt taccaaagaa gaacgtgaat
    42661 caggtttgac caacattgtc atgggacttt ctttcatcac cgaaggagca attccgtttg
    42721 gtgcagctga cccagcacgt gcgattccta gctttatcgc aggttctgcc ttgacaggag
    42781 ctcttgttgg tttggctggt attaaattaa tggcgccaca tggtggtatc ttcgtaatcg
    42841 ctttaacaag caatccaatc ttatatcttg tctttgttgt gattggcgcc cttgtatcag
    42901 gtatcttatt tggcgctctt cgcaaaaaag cctaaaaggt aaagaacttt tttcttacta
    42961 aaactagaat ctgtcaaggt tctagttttt tgctatacta gagttaaagg ataagaaacg
    43021 aggacctttg aaggtgaaaa aaaggagaag aagggctaga tcatcagtaa atcgacttgt
    43081 cttagggtta gtattactta atctgattgt tagtatgtgg acactaaaat tgggaaacca
    43141 gcgattagct ccgtatgcgg atcacgaaac tctgacattt gtcaggaaga ttagtcatgc
    43201 tgctcaatca gtcgctcaaa agaaacagtt atacagttcg gtgatgatgg ctcaggccat
    43261 tttagaatcc aataatggca agtcacaact aagtcaaaaa ccttattata attttttcgg
    43321 gattaagggg agctataaag aacggtcagt catttttcca actttagaag acgatggaca
    43381 agggaatctt tatcaaattg atgctgcttt tcgttcctat gggagcctga cagcttgttt
    43441 tttagattac gcaagagttt tgaatgatcc actttatgac aaaacccaca aaaagttttg
    43501 gtctcattat caagatgcta ctgcaacctt aacaggcact tacgccactg atacaactta
    43561 ccataccaaa ttaaatgaat tgattgaatg gtatcaactc actaattttg atggtctaat
    43621 gaaatagtta tccacaattt taaaaaaaat cagaagaaat atgtcgattt caagacaaaa
    43681 gttatcaatc tcattaaatt atctgtggaa aagttaattt aaacgttcgt gtgctataat
    43741 agaaacatag aaaatgtata aaaaaggata tgtgaataat gacaaaaaag aaaggtaagc
    43801 ttgtacttat cagtcttttt gttctagcag cttgtttagg agcttatagt gcaatgagac
    43861 aatctcataa aacttcaaac gtgtcagctg agactatcgc cagttcttca acccgacatt
    43921 ttattgatga aattggtcca actgctagta ctattggtca agaacgtgat ctttatgcgt
    43981 ctgttatgat agcacaagcg attttagaat caagtaatgg taaatcaagt ctaagtcaag
    44041 caccttatta taattttttc ggtattaagg gtgcctataa cggttcttct gtgacgatgt
    44101 caacttggga agatgatggt aatggcaata cctatacgat tgatcaagcc tttagagctt
    44161 atccaagtat tgcagactcc cttaatgact atgcagactt gctaagttct agcacttata
    44221 taggtgctag aaaatcaaac acgctatcgt atcaagatgc tacagcagct ctaactggct
    44281 tatacgctac agacaccagt tataacttaa aactaaataa tattattgca acctatggtt
    44341 tgacggctta tgatgttgct aatagctcag ctcaagaaac tggtctagca acttcgggtt
    44401 atgtttggaa tgagtatcgt cgtaattaca ctgatgcgga gaccctagca gttgatgagg
    44461 cttgggctaa acgcatgact tattaatgta acactaacaa caatctgctt gcactgaccc
    44521 caaaaaagct ggatactcta ttttaagtaa aggatttagt tctgtattgt acagaactaa
    44581 atccttttag ttttactttg atatgtttat cgttgtaata atcaatgtca tttgtaatcg
    44641 cttgttctaa gtcttctagt gatttatagt tattctcata accatagaac atttctgact
    44701 ttaagatgcc aaagaaagat tccatcatgc tattgttagg actgtttctt ttacgtgaca
    44761 tagacggacg aattccttta gagtttagga aatgatgata atagttgtgt tgatattgcc
    44821 aaccttgatc actctatcat atagttccat catagcattt atttggagat gtctttttcc
    44881 attattggtt taatgtgatt taagcaaggt tattagctaa acttaatgcc agacaaaaac
    44941 accccaatta ttagattttt tgtctaactt ttggggcgca attcaatctg agcagtttta
    45001 gatttggtat caatgttatt ataggtcaat tgatcatatt tatccaaagc ttttagctta
    45061 tttagtccaa agataaatat caaaatggct gaaatctttc atgtttatag tcttattgtc
    45121 tttatatttt tttaagacat cagatctggt gctattgggt tttgcgtcat ataaattgat
    45181 tttttcatgt ttcctatttt tactgtgaat ttctaaactc ccccttatat aaggagactt
    45241 agtcaaatga atttcttttg attccatcaa aaattttctt attttaaaat cgaactcttg
    45301 aatcgtaaca atatccttat cgatttttat aggatttatt aatgtttttt gctgttgccc
    45361 atctataaaa aaattccctg caatagtatt agtccttaga ataccatcat ctgttgaagg
    45421 tattctttct tattgatacg ctttaattgg tctgattcca actatcttgc cctgttgaaa
    45481 gtgtaaataa ccctagtact tgagcaccaa tattatcttc ttttatttct ttagcagaaa
    45541 tagctacttt tccagcggaa ttaacaccaa caaagtattt cttcatacca atagatgcat
    45601 tactatcaga gtctgttaca taaatagctt taaggttccc gttagaatca aagtcagctc
    45661 cccacaggtt tataacatgg ttgatgcgta cgttagcgta ggtgtgtgat aggcctagag
    45721 ccttgccttc ggttaactct ttcttaatga gatcactgat ttctttgaga tttttttctt
    45781 taaaatcatg acgacttgtc aatagcttac tttgatcacc tcttgtaaat acggcgtcaa
    45841 aaataccacc tcggcgatct ttctcttgat aggttctatt gacatcagta gtctgtgtct
    45901 tataaacatt taagtaataa ccattgataa acatatctaa aacaagatca ggcataactc
    45961 caattcggcg tgctgacaaa ccggggaaag ctttatctcg gaaataatta aaaagctcgc
    46021 tatttgtttg gtcacctttg gtattaataa cttttcttac atccaataat tcttgatcac
    46081 caaacatgat tttttgttta tctgggtgtt tttttagata tgcttcaatt ttttctttgt
    46141 tttgatcgaa ccaccagtga agcatattcc ctgctgtggc agccccgcaa agaagatcgt
    46201 cttttccatt gaatgttttg gtaatatcat accatccttg gttagcaaca taaggagcgt
    46261 gaaaaacatc ttcgccttga gtgaattttg ctggaggagt aactcctttg gtccaaacgg
    46321 aagtaacgtg ataaggtgtt acttccgaat atctaatctc ttgattagca gaaaaactat
    46381 ctgctataac accacgatct accgatagag caaataaagt cactgctgcc aatactgcag
    46441 ctgaagttga atagcatctt tttctcataa gaataccttt ttctatataa ttttatgata
    46501 aagaaa
//
LOCUS       DAUGUF010000013        44652 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUGUF010000013 DAUGUF010000000
VERSION     DAUGUF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44652
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.013"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            28..315
                     /locus_tag="VIB71_000711"
     CDS             28..315
                     /locus_tag="VIB71_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HEQ8822462.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            305..640
                     /locus_tag="VIB71_000712"
     CDS             305..640
                     /locus_tag="VIB71_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8822463.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKISHYHSTKGYTLSKDYIVLYHIEGEENRVAIDYLLPT
                     QSDYIKLFK"
     gene            792..1262
                     /locus_tag="VIB71_000713"
     CDS             792..1262
                     /locus_tag="VIB71_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEQ8822464.1"
                     /translation="MEEFTKPTHKTYSEIFEKWYQAYRDTVEPTTASRTLNLFRLHIL
                     PVMGELPINKTSPLDCQNFITDKAKTFKNIKQIKSYTEKVFDFAIKMKLLKHNPMAEI
                     IMPKRKKTRIENYWTVQELQEFLVIILQKEPYKHYALFRLLAYSGLKERRAMRS"
     gene            1225..1587
                     /locus_tag="VIB71_000714"
     CDS             1225..1587
                     /locus_tag="VIB71_000714"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ8822465.1"
                     /translation="MAALRKGELCALKWADIDFQSETLSVNKSLGRLDGQAIKKSTKN
                     DFSVRKIKLDSETISILQEWKAISQKEKTELAVAPLSIESDSIFTYCTREGSIEPLHT
                     DYINNILSKVIKQHSLKK"
     gene            1623..1772
                     /locus_tag="VIB71_000715"
     CDS             1623..1772
                     /locus_tag="VIB71_000715"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822466.1"
                     /translation="MIEIGVDPVNTAKRLGHASSQMTLDTYSHATAVGEDKSIKQFAN
                     CLKNN"
     gene            complement(1892..2284)
                     /gene="rpsI"
                     /locus_tag="VIB71_000716"
     CDS             complement(1892..2284)
                     /gene="rpsI"
                     /locus_tag="VIB71_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEQ8822467.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2305..2751)
                     /gene="rplM"
                     /locus_tag="VIB71_000717"
     CDS             complement(2305..2751)
                     /gene="rplM"
                     /locus_tag="VIB71_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEQ8822468.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(2969..3175)
                     /locus_tag="VIB71_000718"
     CDS             complement(2969..3175)
                     /locus_tag="VIB71_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8822469.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(3172..3678)
                     /locus_tag="VIB71_000719"
     CDS             complement(3172..3678)
                     /locus_tag="VIB71_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822470.1"
                     /translation="MFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGG
                     VAFVLTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLSMGASIFYRHY
                     LDAKEADE"
     gene            complement(3814..4674)
                     /locus_tag="VIB71_000720"
     CDS             complement(3814..4674)
                     /locus_tag="VIB71_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8822471.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(4771..5289)
                     /locus_tag="VIB71_000721"
     CDS             complement(4771..5289)
                     /locus_tag="VIB71_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEQ8822472.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            complement(5293..6039)
                     /gene="rlmB"
                     /locus_tag="VIB71_000722"
     CDS             complement(5293..6039)
                     /gene="rlmB"
                     /locus_tag="VIB71_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEQ8822473.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKSRGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(6086..6883)
                     /locus_tag="VIB71_000723"
     CDS             complement(6086..6883)
                     /locus_tag="VIB71_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822474.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQTNQSANQEIDSTSNPFRSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLLGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(7079..7492)
                     /locus_tag="VIB71_000724"
     CDS             complement(7079..7492)
                     /locus_tag="VIB71_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEQ8822475.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAHLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(7485..8828)
                     /locus_tag="VIB71_000725"
     CDS             complement(7485..8828)
                     /locus_tag="VIB71_000725"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEQ8822476.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDSEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            complement(8856..9086)
                     /locus_tag="VIB71_000726"
     CDS             complement(8856..9086)
                     /locus_tag="VIB71_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822477.1"
                     /translation="MNKIRVGLYVIMSLSILVFSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(9565..10146)
                     /gene="cysE"
                     /locus_tag="VIB71_000727"
     CDS             complement(9565..10146)
                     /gene="cysE"
                     /locus_tag="VIB71_000727"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEQ8822478.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTIRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(10155..10907)
                     /locus_tag="VIB71_000728"
     CDS             complement(10155..10907)
                     /locus_tag="VIB71_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEQ8822479.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(10900..13032)
                     /gene="pnp"
                     /locus_tag="VIB71_000729"
     CDS             complement(10900..13032)
                     /gene="pnp"
                     /locus_tag="VIB71_000729"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEQ8822480.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGDSTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            complement(13313..14044)
                     /locus_tag="VIB71_000730"
     CDS             complement(13313..14044)
                     /locus_tag="VIB71_000730"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEQ8822481.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCSVIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICLQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDDNH"
     gene            complement(14054..15433)
                     /locus_tag="VIB71_000731"
     CDS             complement(14054..15433)
                     /locus_tag="VIB71_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEQ8822482.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLTFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVIFYLVATVASVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQE
                     AINNVSEEI"
     gene            complement(15460..15744)
                     /locus_tag="VIB71_000732"
     CDS             complement(15460..15744)
                     /locus_tag="VIB71_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8822483.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            complement(15737..17797)
                     /locus_tag="VIB71_000733"
     CDS             complement(15737..17797)
                     /locus_tag="VIB71_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8822484.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQKKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRDVRGEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLDLVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKSVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(18149..18418)
                     /gene="rpsO"
                     /locus_tag="VIB71_000734"
     CDS             complement(18149..18418)
                     /gene="rpsO"
                     /locus_tag="VIB71_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEQ8822485.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(18594..18794)
                     /locus_tag="VIB71_000735"
     CDS             complement(18594..18794)
                     /locus_tag="VIB71_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822486.1"
                     /translation="MTMLGYRLSAEVLGSAILPLLAGYLIRQAIAQVYSDLKTASWLF
                     GLASSVAYGGLVKAKRAHSTTR"
     gene            18920..19177
                     /locus_tag="VIB71_000736"
     CDS             18920..19177
                     /locus_tag="VIB71_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8822487.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTCRIADLDALTQLSVNN"
     gene            19304..19918
                     /locus_tag="VIB71_000737"
     CDS             19304..19918
                     /locus_tag="VIB71_000737"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8822488.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(19951..20493)
                     /locus_tag="VIB71_000738"
     CDS             complement(19951..20493)
                     /locus_tag="VIB71_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8822489.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKEIKANLLSQAEALLAAI"
     gene            complement(20625..21053)
                     /locus_tag="VIB71_000739"
     CDS             complement(20625..21053)
                     /locus_tag="VIB71_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ8822490.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(21163..25560)
                     /locus_tag="VIB71_000740"
     CDS             complement(21163..25560)
                     /locus_tag="VIB71_000740"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEQ8822491.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     ILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMSILGNMPEDNQLSLFDDFF"
     gene            complement(25814..27670)
                     /locus_tag="VIB71_000741"
     CDS             complement(25814..27670)
                     /locus_tag="VIB71_000741"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEQ8822492.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGVNFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLTAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGASIEVNAENLIETLEILTKEH"
     gene            complement(27868..29127)
                     /gene="rseP"
                     /locus_tag="VIB71_000742"
     CDS             complement(27868..29127)
                     /gene="rseP"
                     /locus_tag="VIB71_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEQ8822493.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLIIGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(29200..29994)
                     /locus_tag="VIB71_000743"
     CDS             complement(29200..29994)
                     /locus_tag="VIB71_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEQ8822494.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(30007..30756)
                     /locus_tag="VIB71_000744"
     CDS             complement(30007..30756)
                     /locus_tag="VIB71_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEQ8822495.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNHRQRRFGKV"
     gene            complement(30975..31340)
                     /gene="yajC"
                     /locus_tag="VIB71_000745"
     CDS             complement(30975..31340)
                     /gene="yajC"
                     /locus_tag="VIB71_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEQ8822496.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(31456..31830)
                     /locus_tag="VIB71_000746"
     CDS             complement(31456..31830)
                     /locus_tag="VIB71_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEQ8822497.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSIAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            complement(31945..35442)
                     /locus_tag="VIB71_000747"
     CDS             complement(31945..35442)
                     /locus_tag="VIB71_000747"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEQ8822498.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVMLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGFQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGEHLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDKDTSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADSVKVVVYDKQDQTKVLGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     YGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAKYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTGNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            complement(35640..37253)
                     /locus_tag="VIB71_000748"
     CDS             complement(35640..37253)
                     /locus_tag="VIB71_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEQ8822499.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTNGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSKAQETWLPVNPNYQDINVADALADPDSIFYTYQQ
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDQEQVFAKDLAGAE
                     VVITNTDVDKVLETKHLQPWDAFCLKLKA"
     gene            complement(37382..38515)
                     /gene="ugpC"
                     /locus_tag="VIB71_000749"
     CDS             complement(37382..38515)
                     /gene="ugpC"
                     /locus_tag="VIB71_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEQ8822500.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYSLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(38813..39661)
                     /locus_tag="VIB71_000750"
     CDS             complement(38813..39661)
                     /locus_tag="VIB71_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEQ8822501.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLDQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPADLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAVSIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFQQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            40002..41324
                     /gene="ska"
                     /locus_tag="VIB71_000751"
     CDS             40002..41324
                     /gene="ska"
                     /locus_tag="VIB71_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEQ8822502.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSRPAHGGKTEQGLSPKSKPFATNSSAMPHKLEK
                     ADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKERYHLTTLAVGD
                     SLSSQELAAIAQFILSKEHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYKANSKTGIVEKTNNTDLISEKYYVLKKGEEPYDPFDRSHLKLFTIKYVDVDTNELL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHNDTNRIIT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPKDK"
     gene            complement(41422..41865)
                     /locus_tag="VIB71_000752"
     CDS             complement(41422..41865)
                     /locus_tag="VIB71_000752"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEQ8822503.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     SQLYDSFNEQLAEFVKVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(41880..44099)
                     /locus_tag="VIB71_000753"
     CDS             complement(41880..44099)
                     /locus_tag="VIB71_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEQ8822504.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGHDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            complement(44351..44461)
                     /locus_tag="VIB71_000754"
                     /pseudo
     CDS             complement(44351..44461)
                     /locus_tag="VIB71_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_129544913.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        13069 a         9971 c         8453 g        13159 t
ORIGIN      
        1 ataaattaca taaaggggtt acataaaatg actacagtaa aaaaaaacag agcggttacc
       61 tttcaagcta ataaagaatt ggtaagcgaa gcaatgacag tattaaacaa aaaaaattta
      121 accttatcat ctgctttaag attattccta caaaatgtcg ttgtcacaaa cgaggttgac
      181 ttattgacgg aagaggagtt agagaaagaa aaacttttca agcaatttca agctgaaatc
      241 aacaaaaata ttgaggacgt tcgtcaaggg aagttttata cctctgaaga agtgagggct
      301 gaacttggac tataagaaat atcagattat ctatgctcct gatgttttag agaagctaaa
      361 agaaattcgt gattatattt ctcaaaacta ctcctcaaca tcaggtcagc gtaaaatgga
      421 gcaaatcatt agcgacatag aaaaactcga ggttttccca gaagttggtt ttgatgccga
      481 tgaaaaatat ggttcaaaaa tcagccatta tcacagcact aaaggttaca ccttaagtaa
      541 agattatatt gtcctatacc atatcgaggg ggaagaaaat agggtcgcta ttgattactt
      601 gcttcctact caaagcgact atataaagtt attcaaataa cacgttaaaa gccttagcag
      661 tcttgctagg gcttttttgg tagattacca attaactagg agcaaaatga gttcgggctg
      721 tttaatagat attccacaaa gaagccaaag actacgaagc taggctaatc taccttaagg
      781 cttcaggaaa cttggaggag ttcaccaagc caactcataa aacttatagc gagatattcg
      841 agaaatggta tcaagcttat cgagatacgg tagagccaac cacggcttct cgtactctta
      901 atctgtttag acttcacatt ttgccagtca tgggagaatt gcccattaac aaaacctccc
      961 ctttagactg ccagaacttc atcaccgata aagcaaagac ctttaagaat atcaagcaaa
     1021 tcaagtccta cactgaaaag gtctttgatt ttgccatcaa gatgaaactg ctcaagcata
     1081 accctatggc tgaaatcatt atgccaaagc ggaaaaagac acgaatagaa aactattgga
     1141 cggttcaaga acttcaggag tttttagtca taatacttca gaaagagcct tacaagcact
     1201 acgcactatt tcggctacta gcttatagcg gccttaagga aaggcgagct atgcgctctt
     1261 aaatgggctg atatagactt tcagagtgag acactaagcg tcaataagag cctaggacga
     1321 ttagacggac aggcaatcaa aaaaagcact aaaaatgatt tctcagtaag aaagattaag
     1381 ctagacagcg aaactatttc tattctgcaa gaatggaaag ccatcagcca aaaagaaaag
     1441 acagaactag cagttgcacc tctttcaatt gagtctgact ctatatttac atactgtact
     1501 agagaaggga gtattgaacc acttcataca gactatatta acaatatctt atcaaaggtc
     1561 attaagcaac atagtcttaa aaaataagtc ctcacggctt caggcatacc catgcaaccc
     1621 tgatgattga gattggagtt gacccagtaa atacagccaa aaggttagga catgctagta
     1681 gtcaaatgac tcttgataca tacagtcatg ctactgcagt cggagaagac aaatcaatca
     1741 aacaatttgc taactgtctc aaaaataact aaataaacgt attaaaccaa gtcaaaagtt
     1801 ttccgaaacg gtatcaaaag caaaaaacga caaaaaaagc accttgcaag agacttgcaa
     1861 aatgcttgta atcgttgatg taaagctgtt cttaacgttt tgagaattgt gaagctttac
     1921 gagctttctt aagacctggt tttttacgtt caaccatacg tgcgtcacgt gtaagaaggc
     1981 cagcgcgttt caatgaatcg cggaagtctg ggtctacttg aagaagcgca cgagcgatac
     2041 catgacggat cgcacctgat tgtccaccgt aaccaccacc aacaacgtta acgaaaacgt
     2101 cgtatgaacc ttcagttgat gtaactgcaa aaggttggtt gatgatcaaa cgtaagtcag
     2161 catgtgggat gtattcttct acatcttttt tgttaacagt gattttacca gtacctggaa
     2221 ccaaacgaac gcgtgcaaca gcgtttttac gacggccagt acctgcatat tgtgcttgtg
     2281 ccattattta atgctccttt cctcttagat aagtcctgag atgtcaagta cttctggttg
     2341 ttgtgctgcg tgagtatgct caccgccaac gaagactttc aatttcatac cttgtgcacg
     2401 tccaagagtg ttatgtggaa gcatgccttt aactgatttt tcaatcaagc gaactgcgtt
     2461 tttagagcga agttcaccag cagtgattga tttcaaacca cctgggtaca ttgagtgagt
     2521 gtagtaaact ttatcagttg cttttttacc agttaattta actttttcag cgttgataac
     2581 gataacaaaa tcacctgtat cagtatgtgg tgtgaaagtt ggtttgtttt ttccgcgaag
     2641 tacgctagca actactgcag aaagacgtcc aagtggcaca tcagttgcgt caacaacgta
     2701 ccatttgcgt tcaacttggc ctggtttagc catgaaagtt gttttgttca tgatttctcc
     2761 tatacgaatt cgtaatattt gtttacaagg tgatgggtgt tccgtcccat cgaaggtatt
     2821 tggaaggttc cggggccttt caaatggggt aaacaatacc gcctactatg atatcaaact
     2881 taagaggctc cagtcaagtg ctttagctga ttttattgga ttattttttc tttcgattta
     2941 ggagaatggc agagctgctc tgctggtgtt aacgagaatc atcagcttcc caaaaaaggt
     3001 catctaaagt cttatcaagc actcgacaaa tggcaatgca aagattaatc gttgggttgt
     3061 aatcaccttt ttcaacagcc gcaatggttt gtctggagac gcctaccaaa tctgctagag
     3121 cttgttgaga caaatctttg cctgcacgcg ctgcttttaa tttgaggttc ttcattcatc
     3181 tgcctcttta gcatccagat aatgacgata gaaaatacta gctcccatac taaggttaca
     3241 atatgtcgtt tgaactgcca accctcccca taaagccaac gtaaagagga agcttgcaga
     3301 taccagtccc tctgtgaatc ggctaataaa gagtgacagc cagataacca caatcataaa
     3361 ccaaaaccca atagtgtatc ctttgagaag aatctgtttt tggcgttcat catatttggg
     3421 caacttctga tcgtccctta ccttagaatc tagtacttcc ttgctgtcta gtctcgtttg
     3481 gagctttttc gctgtcttta gcccccatac caacaatatg agaaagctag tcaatacaaa
     3541 agctacgcct ccaactaagt aacgttgaaa actggtctta gccagtaatg ttgctactat
     3601 cacaactaga tccatcactg ctgttatgac aatgaaaccc cattgtgact tagcgagatt
     3661 ttgtttgcta tcaaacatga ttcgtttctc ctttaaatct ttatatgaca taatataaat
     3721 tattttggat attttgtcaa atatatttta cataattgat tgacttaagc agcaaaaaag
     3781 gattgaggat ttctcttcaa tccttataag ggattaacgg gaattctgcc caatcacaaa
     3841 aactgccagg gtgttaggac caacgtgagc tgagataact ggtcctagtg gcatcataag
     3901 aacatcgcta atattctcat gcgccagcag ctcttctcgt aacttttcgg cactaccctg
     3961 atcgcttgta taagagacaa taaccgtcga atccgcaata tctttttcca cttgagccac
     4021 catttctttg atggcttttt ggcgtccccg aatttttgca atgggcacca atttcccttc
     4081 ctcatcaatc cacaaaagag gtttgatact ggctaaactg cctagaaaag ctgaaccttt
     4141 tgacagacgc ccaccacgca tcaaatgaaa aagatcatct actaagaaat aggtgcgcag
     4201 tcgagggatc actgcttcaa caatatcttt agtctccagt aaatttttgc cactatctct
     4261 ggcttctgct gctaaaatgg ttagatagcc ttctcctcct gcagcagcca aggtatcaac
     4321 aatttcaatc accgcatcgg gataatcttc tcgaacaaga tcgcgtgcca ttagagcgct
     4381 ttgataggta cccgataaaa ccgaagaaaa agcaagataa agcagtgctt tgttgttcct
     4441 agcatgttca cgaaaaacct tctcaaactc tcccacatta atctgactgg tttgaggatg
     4501 actgccagct ttcatctttt tcaaaaggta atcactacta atacggttag gaccgaccgt
     4561 ttcataaacc tctccatcgc acaaaatcgt taatcctata aggacaatat catgatcttc
     4621 tgcccaggtt tgattcaaat cagcggttga atctgtcatt attgtaaagg tcattcttac
     4681 ttctcctcat ccagtttttt agtttgataa tcaaataatt attgttttat tttatcaaaa
     4741 aaacccgcac ttggcgagtc gtaattctca ttatcgatct aactgagaca taaaatcctt
     4801 caattgaata agctgtcctt ggtcaaaagg ccgcagttta ggcgttttga gatcaatatc
     4861 tctagacatt ttatctaaat cagctttgac agtatgaact ctttgctcta attctcttgc
     4921 agtgacacga agagctcctt gagaaaaaat cgtccattgt tcatttaaat cactcgtagc
     4981 tacttctacc atatgtatag ccgtatttaa ctctgctgcc atgcgctcaa tgtagctatc
     5041 tgctgtttcg tcttcctctg taaataccac tgagatataa tactggtcat atcgttgcct
     5101 tagccccggt acatattggg catcaaaaac acaaataata ttaatattct caaaatgggc
     5161 ataatgatta agttttgtta aaagtgtgtt acgtgcctga tcaagctgat ttgtcttaaa
     5221 caactgacgg gttgattgcc aaaaggcaat catattatac ccatctacta ataatatccg
     5281 ttttttcata atttagcgcc tatttcggaa aacttcatac atgagaatag ctgccgctac
     5341 gctagcattt aagctctgta cgtgaccatt cataggaatc gtaatcattt catcaacttg
     5401 ctttttgata ttggtagaga tgcctttgcc ttcgttacca atgactaaag caagtttacc
     5461 attagtgttc cagcaatcag acggtgttcc attcatgtct gtgccaaaaa tccagaatcc
     5521 tcttgatttc aatttatcta gagtttgact aaggttagtt actctcgcta tcggaatatg
     5581 ttcaacagca cctgtagacg tctttgaaac cactggagtc acaccaacag aacgatgttt
     5641 aggaataatc actccacata catttgtagc atcagctgtc cgtaaaatcg atcctaaatt
     5701 atgaggatct gtcagaccat ctaaaataag aatcaaagga tttgcttctt gctctgctat
     5761 ttcgaggatc tcatcaacat cagtataggc aaaagctgat actctcagaa caaaaccttg
     5821 atgcacagct ccatcagtca tttgtgacaa ggttttttta ggcgtccatg aaatagcgac
     5881 ctttttttgt gtcgctaagc ttttgatgtt atccactttc tttcctctta aatcctcttg
     5941 gatataaagc ttatttcctg tatttgcttg aaggctttct gtaacggcat gaacaccata
     6001 gacgatatcg tttgtttcaa tagtatcttt atcttccatg agtttattat accatgaatg
     6061 cttcaaaata aatgcataga ctcttttatt ttcgtctaga tactttttga atagctataa
     6121 ataaacctgc agctaaactg actactagac ctaataagac ccaagggaat cctctttttg
     6181 aagtaggttt tacttcctct ttgtccacta gcatttttgt cttgttgcta ccgttttttt
     6241 ggctattact agcagttggt gtaagtttct catttttagt agatcgcttt aaggaagttg
     6301 atcgatgatt agtagctgat ctgaaaggat ttgaagtaga atctatttct tggttagctg
     6361 attgatttgt ttgagctttt gtgtctacat cgaccgaatt cgtcgttgct ttagaagtat
     6421 ccttttgttg catattagtt ggtgtttttc tagctttgtt ttgatcaaaa tgaacagttc
     6481 ctgattgacc agttactgcc ttttcttgag tatgaacggt gacagttaca tgatagtcac
     6541 cactcttttg tccagttaaa tcaaaccaag ctgtaaaacg acgctgttgc gctgccatag
     6601 tatataccca actattaata gtattatcac tagcgtcttt aagtgttatc gttgcctgag
     6661 ttggttgtct gacaggttga tctgtggtga ctgtagcatc aatataaggt tctgttccac
     6721 gcatactggc ttcaacactg acctgactaa tagttgattc agctataaca ttatcagtgt
     6781 gctgatcttg tgcatacaca gatatggctt tgccagaagt ccccagcaaa ccaataagta
     6841 aagctagtga taataagcta actgtttttt gcatagttgt cataataaat atctcctctt
     6901 taaattagtc ttaccctctc attataaact attcgaaaat gatttcatta tttttatgtc
     6961 ttttttgtta caaatgtatc ttttttatat cattatgtct ttttgatgtc ataaaaagac
     7021 ttaatggctc tctaccttta cttcagacct atgaaaataa gagtctccta ggggactctt
     7081 atgaggatat caattgttgc ttttctacat actcaataca ccatctgatc aattcttcta
     7141 accgctcttt ttggcccatc atatcaagat aacccataat ggcttcaaag cctgtcgaca
     7201 tacgataggt aataatatcg gcattcttag ctttagtatg gctattggta ttgcgaccac
     7261 gtttatagat gtcttcttct ttttcggtca ataggtgcgc ttctaacata gcctgaatca
     7321 agttggcttg tgccttagca gaaacatatc tcgttgctaa acggtgtagc tggctaggtt
     7381 tcgttttacc ttgaaaaatg agatgacgac gaacatagta ggagtaaacc gcatcccctt
     7441 caaaggctag ggcaatacca ttaatcaaat tcacatcaac tggattagtc acgcagccac
     7501 ctcacaccat ctttggtatc tagcagcttg atgccttgag ctgctaactg atctcgaatg
     7561 gcatcagctg tggcaaaatc acgattcgcg cgtgcttctt gtcgcttagc aatcaaggct
     7621 tcaatgtcaa cctcaagcac ctcttcttca aagataatgc caaaaacagc taacattttc
     7681 tcaaaagcgc ttttaacagg ttctgtataa gagccagaat taatccactt agccatgtca
     7741 aatacgacgg taatcccatt tgctgtattg aaatcatcgt ccatagcgtc ttggaaagct
     7801 attacaaact gttttagctc ttgctcatct gcagtttctg tcagcggttg ttgcaaggtg
     7861 tttttaagat acttcagatt gatttccgca tcatgaatag ccttttcagt gaagttaatt
     7921 ggttttcggt actgttgtgt cgcaagaaag aatcgcaaaa cctgaccatc aacggtttgt
     7981 aacatgtcat gaacggtcac aaaattacct agtgacttgg acattttttc gctatcaaca
     8041 gtgacaaacc cattgtgcat ccaatagtta gcaaaagtct tgcctgtttt ggcctcagat
     8101 tgggcaattt cattggtatg atgaggaaat tccaaatcag ctccgccacc atgaatatca
     8161 atggtatcac caagaatttc agtagccatc acagaacatt caatgtgcca gcctggacga
     8221 ccaaaccccc aggggctatc ccaagaaacc tcacctgcct tagctgattt ccaaagagca
     8281 aagtccagtg gattttcttt taaagctgtc tcagcatctg ttcgaccact ggctccaact
     8341 tcaagttctg acagggtttt attagctagc ttagcataat gctctgactt ttccacgcgg
     8401 aaatacacat ctccatctgc ttcgtaagca aaatcttttt caatgagact ttcaacaaat
     8461 gaaatgattt ctgctatata atccataaca cgaggatttt gtgtggctgg cttaacaccg
     8521 agtgccttgg tatcttctat aaaagctgca ataaagcgat ctgataattc tttaggagaa
     8581 acacctgctt gagtagcagc tttgataatt ttatcatcga catcggtaaa attggaaatg
     8641 taattgacct ggtagccagt atactcaaaa taacgtcgaa tggtgtcaaa agcgaccgct
     8701 gatctagcat ttccaatatg aatataatta tagaccgtcg gtccacaaac gtacatattg
     8761 actgtatttt cagtcaaagg tacaaacttg cggagcgaac gggtcatggt atcataaatt
     8821 ttaatcatgt aaactcctta ttcaatagcc tggcattagt tgtcatcttg atatcctaag
     8881 tctttttctg aaatgctgtt ccaccttttc aacaatttga tattaataac caaacctatt
     8941 aaccaaaata gggtcaaaat gaagtatata atcgctttaa ccatgtcttg tctcagtaaa
     9001 aaaattagac tagccaccag tgtaatacta aaaacaagga tagacaaact cataatgaca
     9061 tacagcccaa ctcttatttt attcatgagg ctcctttatt aacgaaaaac cttcacaacc
     9121 tgtgaaggct tcagaaagta gacaaaccca cttttatgct caaaaagcat gaatagatct
     9181 actgatttga catcaggttt cctatttctg catgtggggt gagccaaaac agctgctttt
     9241 tgttgtggta aaagtggcat caatattgac agtgataccc atacggattt ttgagatctt
     9301 aggctcaaaa ctaaggcatg gaattccaaa ggaagtcgct gccgtaagca ccacctgaga
     9361 aaaagtatca caatagactg tttcttcagt ctaagacttg cttagttgat gctcttttac
     9421 gcgttttttg tattttgtaa cattcccata tcactacact cagcaaccaa actgataggg
     9481 ctagctaagt tcaacattac tctactagaa agtcccaaaa tattttattg gaagtcatca
     9541 gcgcttcttt ttgttatttt ccgatcattt tgacaactga taagagacct ctcgttgttt
     9601 ttgtaaactt tgaatttgac gattatcttt ttgcccatgc actcgtacta tcttagctgg
     9661 cacacctaca actgtcacgt cttcaggaac atctgataac acaacagctg ctgcccctac
     9721 tttagcattt gctccgatgt caataggtcc aatcacttgg gcatgtgccg aaattaaggc
     9781 accttgtcga atcgttggat gacgcttgcc acaatctttt ccggttccac ctagggtcac
     9841 cccatgataa agcatcacac ctttttcaac aattgctgtc tctccaataa caagaccagc
     9901 accatggtca atgaagactc caggagcgat ttgtgctcca ggatggattt caatttgtgt
     9961 ccaaaatcgc caaaattggc tatgcattct ggctagtaat ttaaaatgat gtcgccaaag
    10021 aaaatgagac aaacgatgag cagctagggc tttgatgcct ggataagtta ggataacctc
    10081 aagactatta cgagcagctg ggtctagagc tttaacaata gctatacttt ctttccacca
    10141 acccatacta actcctacga cttatctaat tctgaccaat caacaagaat ttgttggtca
    10201 tcaaaaggat tgatggcgac accgaacgtt tcatcaagct cgttttcacc atttcttggt
    10261 tgataaatat catcaatcgt ccaagtcaga atcactcctt cagctttcct gaaaaggcct
    10321 ccaaaatcgt cttggttgta ccatttcgca aagctttgaa gatttgaaaa ggcgggaaca
    10381 tagctttttc cttcaggcgt tgacatggta ggaaaaaggc ggtcgtaatg gttattatct
    10441 ttaggataaa caaaggcagg aacaaggtaa accttttcca tcgtatctgc cgccacattg
    10501 tcatcactca taagcgtatt taacacagtg gtgtaatggt tcataaattg aatcatatca
    10561 ctgcttttga aaatggtaga attcccaaaa tctccctttt tcttaaggtt aaagacaaga
    10621 cctgctgcac cagatgtaat gacttcttct agcactgcaa gagctgaacg ctccagccaa
    10681 tactgacttt gagcactctt ttgttcttct ttaaagcgag ccatatcttc cttatcggta
    10741 aaaacagggg taaccttgac accttcgact tctatcacgt agggttcttt agcagcccag
    10801 acaggaaaat tatggaaagc gttgacaagc gcaaggctat ccaaaaagtt atcaggcgca
    10861 ttgataaaag ctcttaagcg aatatctaat tcatttgatt tagtcatgtt tttcttcttt
    10921 tttctctggt tttggtgggc gtggaatcaa agctttcatt gaggcatcca cacgaccctt
    10981 ctcatcaatc ttaatgacct taacatcaac gtcttcaccc acttcaagga catctgacac
    11041 gttggtcgtt ctagtccaag caatttcaga aatgtgaaca agtgcatctg tcttgtcaaa
    11101 gaggttgaca aaggcaccaa atttctcaat acggacaacc ttagcatggt aaacttcgcc
    11161 taccttagct tcacgtacta ggccagcgat gatttcttta gtgcggttaa tggcagcttg
    11221 gtcacttgag tagatagaga catttccttc gtcatcaata tcaattttga cacccgtttc
    11281 ggcaataatc ttgtcaatag tttcgccacc tttaccgata accactttga ttttgtctac
    11341 gtcaatcttg atggtgtcaa ttttcggtgc agttggggct aactcaggac gtggttcagc
    11401 gatagttgct tcaatcacat caaggatttc aaagcgagct tttttagctt gtgcaagagc
    11461 ttcttctagg atttgaggcg taatccctgc aatcttaata tccatttgaa gggctgtaat
    11521 cccttcacga gttcctgcca ctttaaagtc catatctcca aagtggtctt caagaccttg
    11581 gatatcggtc aagacagtat aatttgtccc atcggaaatg agacccatgg caatccctgc
    11641 cacaggagcc ttgattggta caccaccagc catcagagca agggtaccag cacagataga
    11701 agcctgagaa gacgaaccgt tagattctag aacttcggca actaaacgaa tggcataagg
    11761 aaactcttct aagcttggca agacttgttc aagagcgcgt tcacctaagg caccgtgtcc
    11821 aatttcacga cgaccagcag ctccgtaacg acccgtttca ccaactgaat attgcgggaa
    11881 attgtagtga tgcaagaagc gttttttgta ctctggggcc agaccatcaa tgatttgagt
    11941 ttctcccatt ggtgccaagg tcaaaattga tagcgcctga gtttgaccgc gcgtaaaaag
    12001 acctgatcca tggacctttg gcaagaagtc aaccacagca tcaagcggac gaatttcgtc
    12061 aatcttacga ccgtcaggac gaatcttgtc ctctgtaatg aggcggcgca cttcagcatg
    12121 ctccatttgt tcaaggattt ctgccacgtc acgcataatg gttgctaggt tttcgtcttc
    12181 tgcgtaacgt tcttcgtatt cagccttaac catttcttta acggcttctg tggctgcttc
    12241 acgcgctttt ttctcttcaa cttgaacagc tttttgcagt tgagcattgt acttagccac
    12301 aatatcagct tgtaagtctg catcaacctg taacagttca acctcagctt tctctttacc
    12361 aacaactgct acgatttgtt cttggaaggc aattaattct tgaatggctt ggtgaccttt
    12421 taaaagagcc tcaagcatga tgtcttctga taattctttg gcaccagatt caaccatgtt
    12481 gatggcttct ttgctaccag caacggttaa ttctaagagc gacgcttcca tttgttcttt
    12541 atctgggttg atgatgaact cgccatcaat atagccaact tgaacacctg caatcggtcc
    12601 attaaatgga atatctgaga tggacaaggc cagagatgag ccaaacatcg ctgccattgg
    12661 agcgctagca ttttcatcat aagaaaggac agtgttaatc acttgtactt cgttacggaa
    12721 accttcggca aacatgggac gaatcgggcg gtcaatcaag cgagctgtca aggtcgcatc
    12781 tgttgaaggg cgtccctcac gtttcatgaa acctcctggg aatttaccag cggcatacat
    12841 tttttcttcg taattaactt gaagagggaa gaaatcaccc gttgccattt tcttagacat
    12901 gacagctgcg gtcaggacag ttgagtcgcc ataacgaaca acggttgccc cattggcttg
    12961 cttagcgact tgaccaactt caacaacaag gggtttccct gcaaatgttg ttgtaaaggt
    13021 ttgttttgac atatattctc cttttaattt tcagaggggt aaagaggtac ctgttctctg
    13081 cttagattca attgttatac gttgttttgc tacaaaaagc aacctgccac gcttgtcaca
    13141 cgctcctctt tgtatcaaac gacgtatctg ctacatttta ccataaaata gcagaaattt
    13201 cactgtcaga tcgcaatctc ttgaaatgtc cttgaaaaat attaagcgaa acttatactc
    13261 ttttaacaaa gcaaaaaaag caggttggta tgcctgcttt cgtctcctaa tattaatgat
    13321 tgtcatcctc taaaatttta aagccgaggc tggtactgtc tttcagaaac atttgcacgg
    13381 tttcaaggga atagtcttct aaatcttttc cttgaagagg caacttggca atcaaatcag
    13441 tggtacaagt gataatgtcc acgcctagct gatcagcttg atagatatta taagtttcac
    13501 gaggactagc ccacaacaat tcgacccctt ctttttgaag acaaatgcgt agagcttctt
    13561 ccatgattgg cattgggtca acgccggtat ctgcaatacg accagcaaaa acagacacaa
    13621 tagctggcac tccagcggtt aaatgatcaa ccacagcttg agtctgctca attgtaaaaa
    13681 tggctgtgac gtttaactta atgcctttgg ctgacaactt ttgaataacg gaacaagttg
    13741 attcgcctgt tgaagtagtg actggaattt tcacatagac attgtcacct agactggcaa
    13801 ttttctcagc ttccttttcc atgcttgcga gatcatccgc aaagacttca aaggacactg
    13861 ggtagtctgt aattttggca agcacttctt tggcaaagcc aatataagaa ctgatgcctg
    13921 cttttttcat caaacttgga ttggttgtaa agcctgtgac caaacctgtt tgtaaatcct
    13981 ttaacatggt ctctaagacc gcaccgtctg aaaagacttt aacgtttagt ttttttgtca
    14041 tcatgtcctc cttttagatt tcttctgaaa cattattgat ggcctcttga gattttgaca
    14101 gaaagtttgg aagcaccaat acaatagcaa gcacagcaac caccaagtaa ataccgattt
    14161 gaccaatcga cgttcctaag cggcccagta aaatccctaa aacaccgaaa tccacatctc
    14221 caaaggtcgt gtttgaaaaa ccaagtttac caagtacagg tagaagcatg gctggcaaga
    14281 aggcgagtaa taagccatta gcgaaagcac caatcatcgc accgcgacga ccacctgttg
    14341 aatttccaaa aatccctgct gttgcaccac agaagaaatg aggcaccata cctgggataa
    14401 tcaggacacc acctgcaact cctaaaatca acatcccaag taagccacca acgaaacttg
    14461 acgcaaaacc gatgataaca gcggttggcg cataagggaa gaataccgca cagtctacag
    14521 ctggaatagc atttggaatt aatttgttag caataccttg gaaggctgga atcaagtcag
    14581 ccaaaatcat gcgaacaccg gcgtagacaa ttgccacacc aaccgcaaag gtaagaccac
    14641 tcttaatagc aaagataaat gggttttgac ctgctgctaa ttcttctgtt actgaagcat
    14701 tcctcaaaac agaagccact gttgccacta agtagaaaat caccatgata agtcctgttg
    14761 aaatggtggt gttgcgtaag aaactccatt tttcagaaat ctgaaggtcc tcggtatctt
    14821 tactgtcttt gccaaccttg ctaccaaccc aggcagaaag gtaatagccc aaactaccaa
    14881 agtgtcccat ggcaatttca tctccgtcag tcactttcaa cgtatactgt tgaccaatgg
    14941 ctggcgaaat agctgaccaa gctcccaaga ggaacccacc taagataatc aaaagacttc
    15001 ctttgaaacc aacagctcca agcacggcgg acaagagaca agccataaag aagctgtgat
    15061 gtcctgttaa gaaaatgtat ttgaagcggg taaaacgagc aaaagtcaaa ttgagcaata
    15121 acccaaccac caagatggac atggtttcca cacccagaat cttttgagcg acagaagtga
    15181 cggcttcatt atttggcact acgccagtga tgctaaaacc gtgctcaatg agtttggcaa
    15241 gagggtctag attggtcaca ataacacccg cccctgcagc aagcataagg tatcccaaaa
    15301 ttggccccaa ggttcctgtc aacaccttat gagcaggtgt tttcaaagcc accaaccctg
    15361 caaaggcaat caagcccatt aaaaatgcag gttcttttaa aatatctcga ataaatgata
    15421 ataatgcttc catagtatct tcctatctcc tttaaaggct tattccttgc cactcatttc
    15481 cttgagaacc ggaaccaaat cttcttcaat ttttttacga ttggtatagc ttttaacgat
    15541 acaaaccttg gcatcctctg gaaaaatatc tttaaattct ttaacggtaa caaacaaatc
    15601 tgcacccttt ccaacagccg cattggaatc acaggattct gcatccacat caatacccaa
    15661 actagatgcg atagcttcta ctttcatgcg aagtaacaag ctactaccaa taccgtttcc
    15721 acaaaccgtt acaattttaa tcatgtgatt catctccttt ttcaatcata tggctaatca
    15781 gactcattat ttcctcagta ttcttagcct caattaattg ctcaatatgt tcatcgtcat
    15841 ctaaaatcaa cgacagttcc tgcaaagcct tcaaatgtga actagaatcc acagcagaca
    15901 aaacaaaaat caattgcact tgcttgtctg gatcaccttc ttgcttcaaa tcaaagctga
    15961 caggttcttt tagttgtaag agagacatgc ctaactgccg cgttcctttt tcaggcgccg
    16021 catgaggaac agccacctta ggggctaaaa caatataggc cccaagctca ttgaccgaat
    16081 caatcatgcc atcgatataa gatgtttcaa tcatctggtg ttctagtaaa ggctgagcag
    16141 ccaaacgaat cgcttcctgc caatccgaaa cagcatcagc ctgcctaata aaatctgctg
    16201 ttaacaagtc caatagtcct agacctcctt tttcaatcgt taaatggtta ccaatcaggt
    16261 aacgggataa atcactaaca agtccttctt tattagtaat cgtggtgtgt ttatgaataa
    16321 tactcaacag gtcatccaaa gcgaattgct ctgacaaggg aagatgaaag tcatcacaga
    16381 ccatcttttt caacatcatt ttctcaacag gccccatcaa agcttgcgtc acataaacag
    16441 gtttagcaca gtcaaaagct actgttgaaa aaatcaaatc aaaggaagct ggatccaaca
    16501 actttatttt gtccagctgg tgaatcctaa taaactgtag ctgtggaaaa agttccttca
    16561 aggttgcctc caacatcaga gacgaactaa tgccattagg gcaaacagat aaggctacca
    16621 gctgattgct cggcctcttc ttaggggcct gcaaccatct cccaaaatga atggtaaaat
    16681 aagcaacctc atcttcatta actgatttcc ccaattgttt ttctagagga gaaaggctgc
    16741 gcttgaccaa gtaaaagaga gattcataat cttgtttgat ttgttccttc aaaggattgg
    16801 tcaagttaat gtcgtagtaa agtcggtaat aagctggtaa aaggtgactg tataggttct
    16861 gacgaagttc tggggtatcg gtgatagaca aacccgtatt aaccgccacc gaattgatga
    16921 tttcctccat aatatcatag ataggctgct gaaagactaa gtctaagtca ccttgaatac
    16981 aaccaagtaa cctagattga accaaatatt tttcttcggt tagactgggg aagttgacca
    17041 ataactggtc caccatcgtt tcaacagctg gcgaagctaa aggaaaagtg tccactgctt
    17101 caccccttac atcccgtgaa aatggtcgat gagcgagaag gcagaaaaaa taaatcaaat
    17161 ccctcaattt ctccgaaata aaagttaagt ggttctccct gctcagttcc tccaacgttg
    17221 ctgccatcac ctttttctgg tcgggcaaac caagttcatg caataagtaa ctgaacaccc
    17281 aaggtcctga tgtgacttgc aaaagagaac tgaccgctga ttctaagaga cgccgcaagg
    17341 ctaagggttc tccttcaaaa aaataaccat cctggcgatt gtaagctaaa gttacctgaa
    17401 aagcttgtac ccgatcacgc accaagttta aatcagcaat aacggaattt ctgctgagcc
    17461 gtaacaaact ttccaagtgg ttaatggaga taaattcttt agccatcatg atgtaaatga
    17521 taatcatgtc cagacgctca tcttgaaaga gatagtcgtc taaggtaggt agcatgcgat
    17581 tcaacaagtc cttttcagta aggtctggcg gataaaccag ctgcctgtcc agagcaataa
    17641 ggggtaactg atagagtgac aacgtgtcat tgattttagc aatatctgcc agtatatgac
    17701 gtttgcttgt ctttaatatg gattcaaatg cctccagtga atgtccttta tatttagaaa
    17761 agagttgata gtttctgatg agctcatgag atagcatgtc atctcctcct ataatgtcag
    17821 tataaaatga agcgttttca ttttcaagac aaattgagtc caattgtctc tcgtcatttt
    17881 tgactgcaat tggactcaac aggtgatatc attgtaacaa gttcctcaaa aggtggcaaa
    17941 aaataggcaa atctgggaat tgattccctt tttcttcatg atacaacaaa agatacctca
    18001 tcactgagat accttttgtt gctaaataaa atcatcaact gctaaaaaaa cagtcttaga
    18061 ccattctagc caaatgtgaa aactaacaaa caacatgtca aaaatgaaaa agcccactgc
    18121 ataagcagag gactttttaa acttgaaatt aacgacgaag tccaagagat tggatcaact
    18181 cacggtaacg gttaacatct gtacgacgta ggtatgccaa caagttacga cggtgaccaa
    18241 tttttttcat caatccacgg taagtagcgt ggtctttttt gtgttctttg atgtggctgt
    18301 tcaagtggtt gatttcccat gtaagaactg caacttgaac ttctactgaa ccagtatcgc
    18361 cttcgtgacg tgcatattga gcaatgattt catttttttt ctcttttgag attgccataa
    18421 tatattctcc tttttttgct taatccgagt cctaggattg gcactcctaa aaccaagaaa
    18481 aagttggttt gtctttcgac cactctattc tagcagattc ataatattag gtcaaccgtt
    18541 atcctattat tctgagctct cacatccaaa ccacctcact aggcttaaaa aggttatctg
    18601 gtcgttgaat gtgctctttt tgctttaacc aaaccaccat aagcaacaga actagcaagg
    18661 ccaaatagcc aagaggctgt ttttaaatca gaataaacct gtgcgattgc ttgcctaata
    18721 agataaccag ctaaaagagg taagatggct gatcccagca cttcagctga taagcggtag
    18781 cctagcatag tcattcattt ctttccaaca aagtgttcac tgataatatg aattgctcta
    18841 gtattaacaa acccaatccc taatccatga acacagctta ttaaccgatg cgacctgcct
    18901 ttatgacata ggtcaagagt tgacacaaaa tgtttgccaa caaaacatta cctataccgt
    18961 caaagagcgc tttgcttcct atacccttga agcgcaagcc aaccaagagg ttcatctaaa
    19021 ccttacatta ttagcaaacc gttttggaac aagcgatcgc catcttaagc acgtacttaa
    19081 gcagcccatt tttcagagga ttatcgaacg catctgcttc aaaacctgtc gtattgccga
    19141 tttagacgct ctaactcaat taagtgttaa taactagacc tctgaggtat gcagcccatt
    19201 aacttataat agcaatcact ctaaccacta cctgactttt ctttaaaaaa gaaatgattt
    19261 gtgatatagt aaatccagtt aaaaaaaaag taaaggagta gacatgtctg cacaagataa
    19321 attaattaaa cctagtcatc tgattaccat ggatgacatt attcgtgaag ggaatccaac
    19381 tttaagagct gtcgccaaag aagtgagctt acccttgtgt gatgaggata tcctattagg
    19441 agaaaagatg atgcaatttt tgaagcattc tcaagatcct gtaatggcgg aaaaacttgg
    19501 tcttagggcc ggtgttggtc tagcagctcc tcagattgat gtgtcaaaac gtatcatcgc
    19561 tgtgctcgtt cctaatcttc ctgataaaga aggaaatcct cctaaagaag cctatagctg
    19621 gcaagaagtc ctgtataatc ctaaaatcgt ttctcattct gttcaagatg cagccctttc
    19681 tgatggcgaa ggttgtttat ctgtcgatcg tgttgttgaa gggtatgtgg ttcgccatgc
    19741 tcgtgttaca gtagactact atgataaaga aggacaacag catcgcatca aattaaaggg
    19801 atacaacgct attgtggttc aacatgaaat tgaccatatc aatggtgttt tgttctacga
    19861 tcggatcaat gctaaaaacc cctttgaaac caaagaagag ctcttgattt tagactaaca
    19921 aaaaaaggct aaagggcctt ttttgttagt ctaaatagcc gctaaaagag cctctgcctg
    19981 agatagcaag tttgctttta tctcttttga aatctcaagc cttcctgttc cccaggcatc
    20041 aggattcaca gttgcttttg taaactctcc tgctactgaa gttcggataa acggcaatag
    20101 tgctttaaac tgatcaaata cttgatcatg cccgccattt gcaactgaag agaccgtaac
    20161 caccttaccg ccaatagcag atgggcccgt cggatcagac aaatcaagag cacgagacaa
    20221 ccagtctagc aggtttttaa cagaacctgg aatagagaag ttgtaaactg gtgtaaaaat
    20281 ccagatagca tccgctgact gaacagcttg acgagcgtca acaactggta aaggtgcatt
    20341 agcttcgata tcttgattca aaacaggaac gtctttccaa tttaagtaag atacaactgc
    20401 ttgatgttcc agagcttttt gtgcttgagc cgctaattga tggttaaaag acccttcacg
    20461 aagcgagcca acaataaata aaatatgttt catctctttg tcctcttttt tttaaagatc
    20521 gttttaaagc tttctaaaag tggtatttca ttgatacttc tttttgaaat ttatcactat
    20581 gtagtaatta tatcttctct aagaagagct gtaaagagat ttgtttataa ttgtttgaac
    20641 tttttgagaa gttcaatcag acaaagttgt tctttttcag tcaaaacagc aaaggcttct
    20701 tccacccgtg cgacgtgttt aggcaaaaca gcttcaatca agcgagtacc cttatctgtt
    20761 aaggtaacca cataggctct tttatcagtt ttgtctttgc acttgctaat ccagccattg
    20821 cgttccatat tatttagtac aacagtcata ttccccgaag tcgctaacaa agaatcaatc
    20881 aagtgattga ttcgcataca gcctttagta tatagtactt caagcacact gaactgcgtg
    20941 gctgttaaat ctgccttttt aaaaatatca gccccaaaag catctagcgt tcgctgagct
    21001 ttacgaaaca ccaccatggc tttcaaagcg gtgttcttat ctaaatgact catttgattt
    21061 cctcgcttta tacggtatgt cacagtttag tatcagagag attagaaagt gatcttgtcc
    21121 ctcttctttt atgactttgc atattactac catcatgata atctagaaaa agtcatcaaa
    21181 aagacttaat tgattatctt ctggcatatt tcctaaaata ctcatctcat ccattttctc
    21241 aacgagcgtt gacgatgccc cgcctcgttt acgcaattcc attttagaga ggaattcgcc
    21301 ttcttgacga gctttaacga tttgcttggc cacgttttca cccagacctt ctaacgctat
    21361 aaatggaggg ataagggtat ctcctttgat ttggaattct atagcatcac ttttgtaaag
    21421 gtctaatttg ccaaacttaa agccgcgttc taacatttcg ttgacaatct ccaaggttgt
    21481 aaagaggtca ttttccacat tggtagcttc attattttta cgttttatag taatatcttc
    21541 cattcttgct ttaacagcat ctaaaccacc actcatggtt tttaattcaa aagccttcgc
    21601 acgaatagag aaataagcac aataatacat aatggggtgg tgcaccttga aataagccac
    21661 ccgaagggcc atcaaaacat aagctgccgc atgggcttta gggaacatgt acttgatttt
    21721 tccacacgat tcaatgtacc agtcgggcac attgttttct cgcatggcat caatatagcc
    21781 attacgttct tcctcagaaa ttttcagcca taatccctta cgcacacgct ccataatggt
    21841 aaaggccatt ttcggttcta agcctgcgtg catgaggtaa accatgatgt cgtcacgaca
    21901 accgataacg gtttttaggg tcgcaatgcc ttctttaatc aaatcttgcg cattaccaag
    21961 ccaaacatcg gttccatgag atagtccaga caactgcaaa agctccgcaa aagtggtcgg
    22021 atgcgtttcg ttaaccatgc cgcgaacaaa gttggtccca aattctggaa tgcctaacat
    22081 accagtcggt gtcccaattt gttccggggt aacgcccaaa atctctgtcc cagaaaagag
    22141 agccataaca cctggatcat cagcagggat agtaatagga tcaatgcccg ataaatcctg
    22201 aagtttacga atcatggtcg gatcatcatg ccctaggata tcaagtttca agacgttttc
    22261 atcaatatca tggaagttaa agtgagttgt ctgccaagaa gccgttacat catcggctgg
    22321 atattgcacg ggggtaaaat cataaacatc catgtaatta ggaataacaa caatcccccc
    22381 agggtgctgc ccagtcgttc gtttcacacc agcagcacct gctgctagac gatccacctc
    22441 agcatcccga tagaacttgc catagtcgcg ttcatagcct ttgacaaatc cataagctgt
    22501 tttttctgct acggtaccaa ctgttccagc acgaaaggcg tattcgtcac caaaaatatc
    22561 tcggacatct aaatgggcac tgggctgatc atcaccagag aagttcaaat caatatcggg
    22621 caccttatcc ccatcaaacc caagaaaggt ctcaaaggga atgtcttgcc catctttttg
    22681 ataaggggtg ccacattttg gacaaggctt attaggcaaa tcatagccag atccaactga
    22741 cccatctgtg ataaattcag aatgttggca ggacgggcaa acgtagtgag gcggcatagg
    22801 attaacctcg gtaatcccaa tcatggttgc cacaaaacta gaccctacag atcccctaga
    22861 accaactagg tagcctcgct catttgaccg gttaacaagc atttgggaag cgagataaat
    22921 cacagcaaaa ccgttcccca agatagaggt tagctctttt tcaatgcgta aatcaataat
    22981 atctgggaga ggattaccat aaatttcaaa ggctttttga taggttaatt cggcaaccgt
    23041 ctcttcggcc ttgtcaatat acggggtgta aagatcgccc ttaaccactt ccacttcctc
    23101 aatacggtcc gcaaaatcct gagtattttg cacaaccact tgataagcga ggtcttttcc
    23161 aagaaaggca aactcatcca gcatttcatt ggttgttcta aagtgcgctt taggtagagg
    23221 agcaggttgg gccccttccc cacggccgat tgttctatta atcatggcac cctgaccgag
    23281 actacgcaca ataatttcac ggtaaatctc ttcttcaggc tctagataat gcacattccc
    23341 agtggcaagc acaggtttct tagctcgttt ccctacttca atgaggtcac gaatcacctg
    23401 ctcaatacct gcttgatctt tgattaattc acggacaacc aatggctggt aaatggctgg
    23461 tggcatgatt tcgataaaat cataatactt agccaaatca accgccgcat caattccttt
    23521 agtcagaacg gcatcaaaaa cctcgccgtc agaacaagct gttcctagta acaacccctc
    23581 tctgtgagca tctaagacgg ttcttggaat acgcggcacc ccttcaaaat atttgatatt
    23641 ggaaaggctg accagcttaa acatattttt aagaccaacc tgattttgca catagatagt
    23701 cgcatgctta atccgcgctt ttttgtaaga atcctcagcc accaaatctg tattgagttg
    23761 caaaagattt ttgatgccat gcttttctct ggcatctctt agaaaaataa acaaaagacg
    23821 tcctgtggct tccgcgtcgt aattggccat atgatggtgg tctagactca cttggaaacg
    23881 cttggtgagc ggtcccaaac cgtgacgttt gtattcagga tacaaatttc ttgcgaattc
    23941 taaggtatca atcacaggct gtgtgatttt gggcaagtca tggcgttcat aattggcgtt
    24001 cataaagccc acgtcaaaac tggcgttgtg ggcaaccaag atactatctt tgcaaaagtc
    24061 ctgaaaagct tttaggacgg taactaatgg cttggcgccc tgcaaatgct tgtcggtaat
    24121 ccctgtcaat tcggtggtaa aggcagaaag aggatgccca ggatcaatga attcatcaaa
    24181 ctgctctaca atatttcctt taaacatttt ggaagccgca atctgaatca ggtcattatt
    24241 catagcagat agacctgtgg tttccacgtc aaagaccaca taggtagctt cgtgcaaatc
    24301 catatcaaca ggatcataag aaataggcac cttgtcctca acaatattgg cttctagacc
    24361 aaaaatagcc ttaattccag ctttgcgagc cctatggtag ccatgaggaa aactttgcac
    24421 attagcatgg tcggtgatag caaccgcctt gtgtccccac ttggctgccg tatcaatcaa
    24481 gctttctact gtcggtaagg catccatggt agacatattg gtgtgggcat gaagttcgac
    24541 ccgcttttgc ccttctggca tcaggtcttt gcggtcatga tggacaattt ctttgacctg
    24601 ctgaacattc atggtaagac tcttcgtaaa aggattggtc tcaatattac cttgtacccg
    24661 taaccaagcc cccttagcaa tcatgtcaaa tttacggagc tcctcatcgt ctttggccca
    24721 tttttggaga gcaaacgagg aggtataatc tgtcatttta aagttgatga tatggcgacc
    24781 tgtcctagtg gtcttgcgct ccacatcaaa aaccatcccc tcaaagacaa ttcggttttc
    24841 ttcggtctca atctcaatca ttggtgtgat ggtcgctttt tcaaatcctg cctgacgctt
    24901 agctgctcgt tccttgtagt caaacttagg agcaggtgtg gcttcctcaa ctggtggcat
    24961 catggcttca agggattttt gggcttccaa attatcctgc acagcctttt tcacaagagc
    25021 ctgacgactg gaaacaaaat ccttggtcaa atgctcagtc atctcctgat ctgacaccat
    25081 atctatggtc aaggtgccaa agccaaaggc ttctaattgc ttgaccaaat taggcagatg
    25141 attgtttcta aaatgatcgt tattcacaaa acctggcgct gcaataatga gtttgtcatc
    25201 ctcataagtc actttgagct ttgagaaaga agatttaaaa ctagcactat tacacggtgc
    25261 atgctcaaaa gcttcttggt aataagcttg aagcagatca tctgaataat ccacctgagc
    25321 agcttggata tcaaaggtta ccttaatgtc agccgcctca aaagttctta tcaaacgatc
    25381 atgcaattca cgataagttg caatcggtaa aaccgccgca aaggcaaaat gaaattccca
    25441 caagcgtgac accgaatgca cctttacctc gataatatca gcagatgaaa aggcacttga
    25501 acgtctcatg tcaagtggca tttctatctg gtccatcaat ttagcgaata aatctgacat
    25561 aattttctcc tgattttact aggctttatt ttatcacaat tcaagatgat tttcgagttt
    25621 tagatggaaa gaaaagcagg gctttcttct gacgttcttt ggctaattta ttccaagtga
    25681 tagctcagct gaggtcattt ttttgtcaat cttttatcgc caagcgcttt tggtaaagca
    25741 aaagccactc tgtatcagac aagttcacag caaaaagagg ccactctaaa caggcagcct
    25801 cttcatttct tttttagtgt tcttttgtta aaatttcaag ggtttcgatg aggttttctg
    25861 cattaacttc aatgctggca cctgttgcct tgattttaat ttccacgata ccttcagcgg
    25921 cttttttacc aacagtgaca cgaattggca aaccaatcaa atcgctatca gagaatttcg
    25981 aaccgacgcg ttcattacgg tcatctgtca agacatcata ccctttagcc gtcaagtcag
    26041 cttctaactt cgccgtcaag tcttgggcca cttgatcttt gacattaact gtaatcaaat
    26101 gcacgtcaaa tggggctaat tctttaggga agttaacacc ccaagcataa cggtaatcgc
    26161 cttttggtgt cttgttcaca aagagacggg catgctgttc aataacagca gacaaaatgc
    26221 ggctaacccc gataccataa caacccatca caattggaac ggctctgcca ttttcatcaa
    26281 gaatcgttgc tcccatgctg tctgaataac gagtgcccaa cttgaagata tgaccgactt
    26341 cgataccacg cgcaaactgg agaacaccat gaccatccgg agacatttcc ccttctttga
    26401 cttcacgaat atctacatat tcagcctgga agtcacgtcc tggattgact cctgtcacat
    26461 ggaaaccatc cttgttagct cctgcaacgg cattggtaag gttttgcact ttgcggtcag
    26521 ccacaatgcg actaccttgt gccaagttga caggcccaag tgagccaaaa cctgcaccaa
    26581 agaaagcacg ggcttcttct tcactagctg gctctaaaaa atcagcagct agatagtttt
    26641 ttaatttaac ggtattgata tggtcatttc caactagcaa agcaacaaca ggttcattat
    26701 ctgccacaaa aagcaaggtt ttgatggttt gtgtttcatc tactgaaaga aaagcagcca
    26761 cttcatcaat cgttttgcaa tgtggtgtct caacttctgc caaggcatct tcagcagcta
    26821 cttttgagga cggtttgtat tcgttagttg ccatctcaag gttggcagcg tagcttgatt
    26881 ctgttgaata agcaatagta tcttcacctg aaatcatcca agcagccaat tctgccttaa
    26941 tctcttctaa gacctctttt ggaatatcat ccattgacgc aatagacttg tcaagaacca
    27001 cccagcgatc aaggtccgta cgagctggtg taatggccat aaattcttgg gaatctttcc
    27061 cccccatggc accgccatct ccaataatcc ctttgaaatc tagaccagct ctggtaaaaa
    27121 tagcttcgta agcttgacga taatcttcgt aggtcacatc taaatcttca tagttgtgat
    27181 ggaaactata gccgtctttc atgataaact cacgggtacg aagcaagcca ttacgcggac
    27241 gtttttcatc acgatactta gactgaattt gataaaggtt taagggcaat tgcttgtaag
    27301 atttgaccgc atcacgcacc aaagtcgtaa aggtttcttc gtgggtcgga cccaagataa
    27361 agtctgagtt atcacggttt ttaagcttat agaggtcctc tccataggtc tcataacggc
    27421 ctgattcacg ccagagatca gctgtcaaaa gagctggtgc caacatttca acagcaccga
    27481 tcttttcaaa ctcttcacgc atgatggtct tgaatttctc aatggtacga tttgccagtg
    27541 gtaaataagc atagatacca gcagaaactt ggcgcacata accggcacgc accataagcg
    27601 cgtggctgat aacctgggca tcacttggca tttcgcgcaa ggttgggata agcagtttac
    27661 tttgtttcat agattattcc gttttaatac atccccttat cctcaaaccc ttctggaaac
    27721 atcaagtaag agtgaagcgg gattattcaa taatttgaat gtgtattcct ttcattttga
    27781 gtaagacctc aacccttgca aatcttaggg ttgaggtctt tttcgatctt taacatgata
    27841 aagtcagctt aagatgacct atcttgatta gaaaaagacg cgcatgatat cattccatgt
    27901 cacagcaatc atcaatacga ccatgatagc aaccccagct agggtgatat aggcctctgt
    27961 ttcttgcttg ataggcttgc gacgaatggc ttcaatgata ttcatcaaga tttttccccc
    28021 atcaagtgca ggaatcggaa tcaggttaaa gatccctaaa ttgatcgaaa gcattgccat
    28081 aagagataag actgactcta agccgttttg agcagcctga ttggacatgt catacatggc
    28141 aacaggtcca cctaatttat tgagactaaa gccaatgatc aatcctttca aagcattcaa
    28201 aatagtaaac gccccactcc aagctaattc tagaccgcct aagagcttat ccttaaatcc
    28261 tgttttcaga ctcgccttaa ctcctatcgt gtatgtcttt gcatgctttt gtggtttcac
    28321 agccaccgtt tttaagcgct gatgtgactt gtaggtgacc ttaatggtct gtgacgggcc
    28381 tagatcccgt gttgcaaggt ctacagcctc agtaagatca ttccagctag tcaccttgta
    28441 accattaatt gcgacaattt ggtcattatc tcgaagacca gccttagctg ctgctccatt
    28501 ttcttgaaca cggacatgat tgctactaaa atctggcatc ccaccttgta aaaagaccaa
    28561 gaggataaaa accacaatcc ctaaaataaa attattcatg ggacctgcaa aattggtgat
    28621 taaacgtccg ccaatactag cattttgata ttgaacatca agcggagcaa ttcttatctc
    28681 agtaccgtct tcttcaacaa tagtagcatc gtgagcgacc ttatatgtct tggtttcttc
    28741 taaaaccaag ccagtaatac tcagctgatc ttctaagtca tagcctgtaa catgcattgg
    28801 gagactcgtt gggtctaact tactttgaga caagttgatg cgcttaacaa aaccttgctc
    28861 attaagggtt aaacttgctg gagtacctgt tttgatctca gttttgtcat caccccaacc
    28921 agccattcgc acataaccgc ccaagggtaa catcctcaag gtataaagag ttcctccttg
    28981 gtcaacatga gaaaaaattt tagggcccat tccaatggca aattctctta ctagaatgcc
    29041 tgatttttta gcaaaataga aatgtccaaa ttcatggaca atcactaaaa taccaaaaat
    29101 aataataaag gttattattc ctaacataga tttcctttca gtctattgct tttttgagtt
    29161 ctgtcgcgtt gttgcgactc caaacattac ctcttaagat tagaataaac caaagagatg
    29221 catgatggga aaaacaaaaa tcatggaatc aaagcggtct aaaataccac catgtcccgg
    29281 gataagctta cctgaatctt tgacaccaaa gtgacgtttg agagcacttt caaccaaatc
    29341 accaaattgg gcaaaaatgg aaaaaagagc gaccaatacc aacatggtca aaaagtgatg
    29401 tggcgcataa acagacctat caatcaccat aaagataaaa gacacaagga ctgcacaagc
    29461 gatccctcct aaactacctt caatggtttt gtttggagaa actgtaggca atagtttgcg
    29521 tctgccaaac tgacgcccaa tcagatatgc tccaatatca gtggcccaaa cgataaataa
    29581 ggccaaaaag accttgtcaa ttcctgacag gcgagcattg atcaaatgtt gaaaaccaat
    29641 cccaacataa aaactagttg caatcggaaa ggctgcatca tcaaatgaat aagctctgct
    29701 atttaaaaca gtacctgcca aaatgaaaaa aaccattaag ctgtaaaaag caacattcgc
    29761 atcaattggt aaaaaagtga ggtaatggtc catcggaact gccaatacaa aggcggctaa
    29821 catggcaaaa acaccttcaa aagaaaagac ttctaacctt ttcattttca gtaattctga
    29881 taccccaatc atggccaaaa cgcctacaaa taattggaat ggtaggtttc ctattatgag
    29941 aaaaggtagg aaaatagcta ctgctactcc cccccaaaca acacgttctt tcataactat
    30001 ctccttttag accttgccaa aacgacgttg gcggtggtta taatccgcaa tggcctttag
    30061 tagctctgcc tttttaaaat caggccacaa gactggtgtg aaataaaatt cactgtaagc
    30121 tgattgccaa ggcaagaaat tgctcaaacg cagctcacca ctggtgcgaa taatcaaatc
    30181 ggggtctcgg tagagatatg gcagatggtc tgtcatcaag taattagcaa tcaaatcctc
    30241 cgtaatatct cctggattta atttggcatc taagacatct tgagcaataa agcgaacagc
    30301 actggtaatc tcagcacgtc ctccataatt gagagcaaaa ttcaaaatta aacccgtatt
    30361 acgttttgtt ttgtcgatgg ctgcatttag cgctgccaag gtatcttcag gtaaacgact
    30421 agtctctcca atcatttgaa tctttacatt gttctcatga agcacaggca catatttgtc
    30481 aaagaaggtt actggtaaat tcatgataaa agacacctca tcttgaggtc tggaccagtt
    30541 ttctgtcgaa aaggcataga ctgtcagaac tttaaccccc aactcagatg cagtaatcgt
    30601 tacttcttgt aaagcatcca tcccagcttt atgcccaaac actctaggtt ttagtctttt
    30661 tttggcccaa cgtccattac catccatgat aattccaata tgctttggga tactccccaa
    30721 aacttttttt gttgatttcg cttttaatcc aaacatgttt tttccttatt gataagcata
    30781 cttatctcat attttatcat atttcacgcc ttttggcttg ttttttatca attagatctt
    30841 atcttcacaa aatgttcatc tatcctctga tagatgtgtc agcttttcat gaacctgtta
    30901 gcatcagaat aactgtttca atccagggat caaaacaaaa aagtttggca tatttcatcc
    30961 aaactttccc cgccttaatg gctttcaatg gcactgtcag tgtcagtgct atctactgtc
    31021 tcaacagcag gctcattaac aacactggtt tcttctgttt caaccagtgt cgtttctgtg
    31081 gtagcttttg ttacaatacg cttaatagct gatagctcaa atgtcaaaaa gacgccatcc
    31141 acatctaaca caatcttttt agctgttgta tcgacttcgt caacaatcgc aaacatgcca
    31201 ccaatcgtta cgacttcgtc tcctttttca atagcgttta actgattttg gcgttcttgc
    31261 gcttgttttt tttgttgacg ttgcataaac caaatcaatc caagcatcac tacaaacatt
    31321 aaaattgttg gaaatcccat aatgtctcct ttttcttcta taaaagtcat gtcttactat
    31381 atcaaaaatc aagcggtata gcaagactag acgttacctg atttcttctt taaacgagac
    31441 gctaagcgca gtgctttact cacgagtcaa aaaagctaag atgtcatctg gtgtcaaact
    31501 tgaatcacat acagcccttt ggtgctgatc gtaactaact agcaaagctg gaactgtcac
    31561 taattggtag ttctcacgaa aggcagcaag ctcagcagca tcagcagcgt tttcgctatc
    31621 cacaaaatag acttcttttt gattatctgt tgccacttgt gccaacttag gagcaaagcg
    31681 gcgacaataa ggacagctcg aacgtcctaa aaagacaatc atgtctttgc cactagcaat
    31741 agctgatgtg acttctgcaa tactcgacgg tataaaattc gcaacgattt cttcaaatgt
    31801 catggatgtc tccttctctt ttggtctcat gatacactaa agtagcaatt ttctcaatca
    31861 caaggtcttt tcacagctca gagcttttat agccgtcaaa aagaatccgc aaacggcaat
    31921 ctttttgtct ctattaacac caccctaatc tttttggcgc ttcatcaaca ggctaatagc
    31981 caataaaagc agagctactc cagctgctaa taagcctttt gaggaggctt cacccgtttt
    32041 tgggagcttt tggtttgttt tagctctttt tggcctagtc attaatgatt tgtctaggtc
    32101 ttttgagcca tctggtgttt tggtttgatg attgcctgtc tgactctttt gctgagaggg
    32161 attagccgtt tttgaggata ctttgaggac cagggcagtt aggccatcaa tagtcaagcc
    32221 ttctttggta aactggactc ccttaggctt agcaatggca gtaacaccag cttgctcagc
    32281 atcagcaagc acttgggctc ctagcaaata gcggtaggct tgaggtaaaa ctaccttgcg
    32341 ggtcttgttg tctgcattga caaagacagc atagcgatct ccatttgatg ccaccgtttg
    32401 gtaacccatg atgaggtcct cttgttgaat accatcttgt cctgcttggg tgatcaaggt
    32461 cacatcccga tctacctcag ctttggttgc ttttgtaaag gcatctgttg agcgacgcaa
    32521 cgcaattagt ccctgtgtat aggcttttgt ttggttgcta atcgggtgag ctatggaatc
    32581 tgttgccttg gcccagtcaa aatgattgac cgcatcagac gaatcataag aatcgtggat
    32641 gaagtaaggg tatttcgcta cagcatcaat cagagtcgcc ttatttggca ccttatcatc
    32701 agacaccttt gtcttgtagt cgggatttag aagctgcttg gttcgtccat attcctgacc
    32761 agaatggata aaggcagtcc cttgagcagt taaaatcatg gtatttccta gacgaatacg
    32821 cttgtgaatc tcttcttcag ccactttagg atccttattg atggatttgg caatgacatc
    32881 atgtaaggtc aggttgtcat gggctgcaat atactgcact acatctcctg gggcatctgc
    32941 ttcaaagtta ctaggctgtg ctttgatcgt tttgaacagt ccttctagat tttttgcgcc
    33001 accagtaata aaggctgctg tgccttcatt tgggaaacct gacttgaggg tatttctgat
    33061 atcatcagag aaaacaccga ccgtattggt tgctttcatc caatcttgat ctgccgcaat
    33121 ttcttttttc ccctcatcac cttggtaggt acgccagcct tcgccaatca taatggtatt
    33181 tggattaatg gctttggctg ccttaaaggc ttgctcaata gctgccgcat catggtcacc
    33241 catcatgtcg aaacgaaaac catctacctt gaattcacga gtcagataag taatcgaatc
    33301 caccaagata cgacgactca tggcatgtgt cgttcctaga cgacctccgc caaaactctc
    33361 tctagctgta ccatcagcat tcataaaatg atagtagttg ggttccaaat cttcaaagag
    33421 ataggttcta gccgtgtggt tataaaccac atcaaaaata acacccatac cacgtttgtg
    33481 aatctcattg acaaggtttt taagctctgc gatacgtaaa gcagggtcat taggatttgc
    33541 cgaatacatg ccagaaaggg caaagtagtg ttgtgggtca taaccccagt tgtaattatt
    33601 gtctgaagac gtgtaggctg ttgagcggct cttgtccagc tcattggcat aaaaataact
    33661 caaaaccggt agcaattgaa cgtgggtaac ccccaagtct ttgagatagt ctagctgttc
    33721 aacaaaagct gaaaaagtcc cataagggtg tgttaactta ccttctagag ccttatctga
    33781 cgtaaaatct cgcacatgtg cttcatagat aatagcgtct tcacgctttt taaagttgtt
    33841 aattttggca aaatcaaggc ctgttggtcc tagtttgctt ggatcaataa aggcagcttt
    33901 tgctgttttg atgtcatcag tagcagtcgc atcattccag gcagcgagag atttggcgta
    33961 aggatccaaa accatgactt tttcctgacc gcgcgtgatt tcataaagat aataatagcc
    34021 tgtgtaatca ctaatgccct tgacgctgtc agaagttaga tgagctctcc aaacaccctt
    34081 gtccgacttg gtcaaatcag cttgaccaag aacctttgtc tgatcttgtt tatcgtaaac
    34141 gacaacctta acactgtcag cacttggaga ccatagcgct aaatcaacag aaccatcctt
    34201 agctagggta gctccaagtt caccatcgta agcatagagt ttatctttta attgccagga
    34261 ttggcgagcg acttggctaa cttctccaaa tgtaacagtg tagactgcac cttgcgcctt
    34321 aaaatcaccc tttaatgtca ttacagacgt atccttgtca agtgtcaatt catcaattgc
    34381 aacagttttc cctgctttgt cagtgatctt gatgttttgt ttcaccgcat cttcatcaag
    34441 cccatctaag gtcgtaaaaa tggctttaat ctcatttggc gtggtttgtt cagctccttt
    34501 gagactaacc tgatcaatat aataaggatt gttgtagact tttgggtcag tgtctttgac
    34561 aaaaacctga gtatgattgt ctaactcttt aaacagataa tcttttggtt gcactttaat
    34621 agcatctcct gtcttacttt tatcaaggat taaaaatccg atttcgttag ctccttcttt
    34681 taaggggaca tcaacataag ctccataagg ccctttatgt gacaagtcaa gtccatttgg
    34741 ccagtcggtc gttggggttt tgacatcttt aaaggtccag acagctaagt tatcgtagtg
    34801 tcccgattga ttgtggtagt tgattcgaag gtaacctttt ttcaaaggtc gataagcgtg
    34861 tgcatggtaa ttctcgtcta tccaaacttc attcattttt ggcgtgagaa gcgagatgtg
    34921 ctggtccttt gaaagatgct ctccagcttt attattaatg agataagaca cttgctggcg
    34981 gtgtttagct gctagtggca catctagata atagccatag tcatcttttt tcgcctttgt
    35041 catggtgata gcaccatttg gccaatcctt tgaaggttga tccacatctc cccacaccca
    35101 aagtcccaag cttcctagcg actcaccagc tggcaatgtt ttaaaatgca tacgcaaatg
    35161 atgctcagca atactagcag gattagctga cgagctgtct aaaactggtt tagcctcctt
    35221 actagacgat tgaaaaccat caccagattt agcattgcca tctccttgtt gagcttcatc
    35281 gcgggctagt ccaacaatgg ttttagcagc aacttgatgt gttaagatac taggggtgca
    35341 ccctaacatg acagtcccag ttgcagcgat tacaaaacct atcccccact tttttaacag
    35401 atactgatag cgctttgatc cttggttgac tttctttttc ataagacctc catttagtat
    35461 aacattcaaa caagactatc ttatcacatt gcgcaagcgc ttgcaagaca tgccgcactt
    35521 caacttagaa cacagctcaa acaatgacta tcacccctta ataggatctc aaaaatcaaa
    35581 cagccaaaac gagtttccgc tcgcttggct gttgggtaaa ctcaaatcac atacaactgc
    35641 taggccttca gtttgagaca aaaagcatcc caaggttgta ggtgcttggt ctctaacact
    35701 ttgtccacat ctgtattggt gatgaccact tctgcacctg ctaaatcttt ggcaaagact
    35761 tgctcttgat cagacacatt gacaacaatc acatatgtct cttctccaag ctgacgctga
    35821 taagcaaaca ctttatcagc tgttggcaag aggtgataat ccgcttcaac tagccagtct
    35881 tgctccttac gcaaggcgat tagttgttgg taggtgtaaa aaatagagtc tggatcagca
    35941 agggcatcgg ccacattgat gtcttggtag ttggggttga ccggcaacca agtctcttgg
    36001 gctttagaaa agccagcatg tgtgtcctta gaccactgca ttggcgttct agcattgtct
    36061 cgtcctacct tacggatgct atccatcaca cgcgcagctg acactccatt tcccatagct
    36121 tccttagcat agttaaggga ctcaatatca ttaacctcgg ttaagtcttt aaaaggataa
    36181 ttggtcatgc caatctcttc tccttggtaa atgtaagggg ttcctcgcat caaatgcagt
    36241 aaaatagcta aagccttggc tgatttttct cggtaagtgc tgtcattgcc ccaaatggat
    36301 aagacccgtg gcaagtcatg gttattccaa aaaagcgaat tccagccttc tcccaacttt
    36361 aattctgtct gccacttgct aaaaatagct ttcagagcag gcacgtctaa ttctttggca
    36421 taatcccact tgggagcgtc aggtttatgt tgaagaccca catgctcaaa ttggaagacc
    36481 atggataact ctttgttttc agggcgagaa tactggcgag caatttcagg cgttgctccc
    36541 caagtctcac cgactgtcat cacgtcatgg ttgccaaagg ttgcttgatt catttctttg
    36601 aggtaatcgt gtaagcgcgg cccgttaccc gtgatctcca agtcaggaac cttcccaatc
    36661 aggtcaatca catccatacg aaaaccaccg atgcctttgg caatccagaa attcatcata
    36721 tcgtaaattt tatgacgcaa agcttcattc tcccagttga gatctggctg acgtttgcta
    36781 aaaaggtgca aataatattg acctgatgca ttatcatatt cccaagctga gccactaaaa
    36841 atagaagtca aatcgttagg ttcatctcgc caaatataaa aatcacgctc aggactatta
    36901 gggttttccc tagcttcaac aaaccaagca tgctcatcag acgtatggtt gaccaccaag
    36961 tccatgataa tcttaatgcc tcgctcatta gctgctgcta agagctcatc catatctgcc
    37021 atgtctccaa aaacatcagc aatcgcttca tagtcagaga tgtcataacc attgtcatcc
    37081 attggacttt ggtaaacagg agataaccaa atggctgtaa tgccaagttt ttgcaagtag
    37141 tccagttgac tggtaatgcc ttttaaatca ccaataccat tgccattggt gtctttaaag
    37201 gatctcgggt aaatctgata aatcgtagct ttatgccacc agtgtttctt cattattctt
    37261 ctcctattaa tcattcattc atcttttatt ttaacgtttt ttctcttttt gtgcaatcgt
    37321 ttgcgcaaat gacatgataa aaaggctgga acccaacctt tttatgaata tcgcttatac
    37381 cttaacgaat agcttgttcg gtatctctgt caaagaaatg ccccttagcc acattaaaag
    37441 tcaagctaac ttgctcccct ggactatgga aatcacgcgc atctacacga gaagcaaact
    37501 cagtttgtcc aagcttgaca tagagcatcg tctcagagcc cagtaactca gaaaccaaaa
    37561 cttctgctgt gacagttgca cttggataag tatcatgcac gatttgtctg ctagaaatgt
    37621 cttctggacg aataccaaaa gtgacttttt tccccttgta accagccgct tcaagcattt
    37681 ttgcttgtcc ttcaggaatc gcaatagcaa gaccatcttc actcacaatg cggccatctt
    37741 taacttccac ttcaaagaag ttcatggcag ggcttccgat aaagccggca acgaatttat
    37801 tagctggaag gctgtacaat tcttgtggcg aacccacttg ttcaatttta ccaatcgttc
    37861 cattaccctg agggttttta gtggcactca tgataacgat acggtctgcc aaggtcatgg
    37921 cttctgtctg gtcatgggta acgtaaatag ttgttgagcc aatcctacgg tgaatctttg
    37981 cgatttcagc acgcatggag acacgaagct tcgcatccaa gtttgacaaa ggctcatcca
    38041 tcaagaacac tttagcatca cggacaatag cacgccccat ggccacacgc tgacgttgac
    38101 caccagacag gtcagcaggt ttacgctcta aaaattcggt caaaccaaga atctgcgcag
    38161 cttccttgac acgacggtca atatcatctt ttttgtactt acgtaatttc aaaccaaagg
    38221 ccatgttatc atacacagtc atgtgtgggt aaagggcgta gttttgaaag accatggcaa
    38281 tatcacggtc tttaggagac ttgtcattca ccacttcgcc accgattttt aactctcctt
    38341 cagaaatgtc ctcaagacct gcaatcatac gaagagtagt cgatttacca catcctgaag
    38401 gtccaacaaa gacgataaat tctttatctt tgatgtccaa gtcaaaatct tcaacggcat
    38461 aatgagtagt attggggtat tttttataga tgtgatttag atttaattca accatgtgta
    38521 actcctattt agccagcaaa cgttctagct gactgcaaag ctagaaaccg ctgatatctt
    38581 ttatatgatg cttttattat aacaaaaata gcgctttcaa aacagagaca aagcgaccaa
    38641 acttctttgg gcaacttgca caatagcagg gctagtcaag tcgtaaggga ccataaacca
    38701 agaaaactat gtaaacacag gccggtcaca ggagccaaaa caagctgaac gatctatcat
    38761 tctccttatc agctacagtc caggcagcaa aaaagaaagc cctgtggctt tcctaatatt
    38821 tcaacaaaaa gagatgagca aaggctaaat catccaattg cttcaagtgt agtcctgatt
    38881 gctgagcaaa tttatcaagt ttgtattgca aggagttacg gtgaatatac aagcgctgcg
    38941 ctgtctgcac cagattgccg tgttctgacc atagcgcgtg aaccacatcg gccatatcac
    39001 tttgaggact taggaattgt tgaaactgac gcgtcaatgc caaaaaagtg tggtgcgaca
    39061 gcaaagacca cagcatcagt cctgaaaatg ttaataattt tctgcctgat tgttgcctta
    39121 aataggccgt taacagctga cattcctcct caaaacactc tctcaatgta cccgcagcta
    39181 cttgatacca ggcatttcca acaaacatgg ttaaggccaa accaaaatca ctttctagcg
    39241 ttggcaagag atcttcaagc cagcgcaaga cctttattga gactgcttgt cggcataaaa
    39301 atgccgtttg ggttgcacta ataggcaaaa tgacctcaag ccctgcaatc atctgttgga
    39361 gcaactcaac taagtcagct ggtaaagcct gctgatgatt aaggtaaatg aactgagaag
    39421 tctcaaacag ctgaggggga ttgccctgat gatcaagcaa ataccgctgc caaggtgacc
    39481 ctagcggctg caagacctca cactgatcca gtcccacctc aagtaataag cgctcttttt
    39541 cggataaaca tgatttggga aaatgcacat attggtcccc ttctttgaca ctcacccact
    39601 ctttatcccc taacggatga gggcctactt gcatctctgg aaaatagtct tttagctcca
    39661 tagccattcc tttcatgacg gtctttaaac cattataaca catgactctt tatcacacag
    39721 ttcggtttgt tgtcagcatt attttgtatt ttctgacttt tttaatcatt aaagctaaat
    39781 aatggttatt catttttagc aagaacattc aatcaaatag ctatttatcg gaagattaat
    39841 ttatgtttat actaaaatag gtattatttc tcttttttca ttatcatgac attatcatta
    39901 agatatcatt taaaaacaat tattaggttt ttgtttgtat ctataaaatt attatgttat
    39961 tctaataatg gggattgaaa cttaactttt aggaggtttc tatgaaaaat tacttatctt
    40021 ttgggatgtt tgcactgctg tttgcattaa catttggaac agtcaagcct gtccaagcta
    40081 ttgctggacc tgaatggctg ctagaccgtc catctgtcaa caacagccaa ttagttgtta
    40141 gcgttgctgg tactgttgag gggacgaatc aagaaattag ccttaaattt tttgaaattg
    40201 acctaacatc acgacctgct catggaggaa agacagagca aggcttaagt ccaaaatcaa
    40261 aaccatttgc tacaaatagt agcgcaatgc cacataaact tgaaaaagct gacttattaa
    40321 aggctattca agaacaattg atcgctaacg ttcacagtaa cgacggctac tttgaggtca
    40381 ttgattttgc aagcgatgca accatcactg atcgaaacgg caaggtctac tttgctgatc
    40441 gagatgattc ggtaaccttg ccgacccaac ctgtccaaga atttttgcta agcgggcatg
    40501 tgcgcgttag accgtatcaa cctaaagccg ttcacaactc agctgaacgc gttaacgtca
    40561 actatgaagt gagctttgtc tccgaaacag gaaatttaga ctttacgcca tcgttaaaag
    40621 aacgatacca tttgaccaca ctggcagttg gtgactctct ttcatcacaa gagttagcag
    40681 caattgccca atttatccta tcaaaagagc atccagatta tatcattaca aaacgtgact
    40741 cctcaatcgt cactcatgac aatgacattt tccgtacgat tttaccaatg gatcaagagt
    40801 ttacttacca tatcaaagac cgggaacaag cttataaggc caattctaaa acaggtattg
    40861 tagaaaaaac gaacaacact gaccttatct ctgagaaata ttacgtcctt aaaaaagggg
    40921 aggagccgta tgatcccttt gatcgcagtc acttgaaact gttcaccatc aaatacgttg
    40981 atgtcgatac caacgaattg ctaaaaagcg agcagctctt aacagctagc gaacgtaact
    41041 tagacttcag agatttatac gatcctcgtg ataaggctaa actactctac aacaatctcg
    41101 atgcttttgg tattatggac tataccttaa ctggaaaagt agaggataat cacaatgaca
    41161 ccaaccgtat cataaccgtt tatatgggca agcgacccga aggagagaat gctagctatc
    41221 atttagctta tgataaagat cgttataccg aagaagaacg agaagtttac agctacctgc
    41281 gttatacagg gacacctata cctgataacc ctaaagacaa ataaccacga tcttctaaaa
    41341 cgatgagatt aactgacaaa aaaagcaagc aacacgctat caacagttgc ttgctttttt
    41401 ctaatctctt agttgtagag actagtgaca tttcgtgtct aaaataatcg taactggtcc
    41461 atcattgatg agactaacct gcatatctgc cccaaaaacg ccacgctcaa ctttcacaaa
    41521 ctctgccaat tgttcattaa aactatcata caactgacta gccaaatctg gcttagcagc
    41581 accagtaaag gcaggacggt ttcccttttt ggtgtcagca taaagggtaa attgcgacac
    41641 agataagata ctgcccttga tgtcttggat agactgattc atcttgccat cagcatctga
    41701 aaaaatgcgc atgttgacta tttttcgcac agcgtaagcc aaatcttctg cattatcatc
    41761 tggtcccaca cctactaaca acaacaaccc ttgattaata gcgccagcaa ttttcccatc
    41821 aatagaaaca gaggcctctt tgacccgttg caagacaagt ttcatggttt tatcctttct
    41881 tagccattgg tccgcttcac gctataaaca tctggaactg ccttgatttt ttcgacaaca
    41941 gtggtcagat gcgtcagatt tggaatgcca aagctcacgt gaatattagc aaacttcatg
    42001 tccttagtcg gctgagcatt gactgtcgat atgctcttgg ttgagtttga taaaatttgg
    42061 agcacatcat taagcaggcc actacgattg agcccataga tatcaatttc agcctgataa
    42121 tctttactcg aattgtccaa gtcccactcg acctcaatca agcgttcttg gtagccatct
    42181 tgactcttaa tgttatgaca gtccgatctg tgaatcgcaa tgccacgccc tttggtaatg
    42241 tagccgtcaa taggatcacc aggtacggga ttacaacact tggcaatccg catcaagagg
    42301 cctgatgctc cttggataat gaccccattt tcactgcgaa ccttgagcac atctttgttt
    42361 tcgtgtttga cctcaccgcc cttaaccaat tcttcagctt ctgctttagc cttggccctt
    42421 tcttcttcac ggcgctcttt ttcggttaac ttgttaaaga cactgatagg actaatgtca
    42481 ccaaacccaa cggctgcata gagtgattct tcgctcttca cactgacttt tggaaggatc
    42541 gcttcaatgc gttttttgtc aaggtattta ttggcaacgt agccctgctc ttgaaaataa
    42601 gacaccaaca aatcacggcc tttattcact gacaattcct tgtcttgatt tttaaagaac
    42661 tgacgaattt tgttgcgagc cttattggtt ttgaccagtt ttacccagtc tcgactaggg
    42721 ccaaaggaat tggcattggt gatgatttca accacatctc ctgtttttaa cttggcagtg
    42781 agaggaacca tacgcccatt aaccttggca cctgttgctt tttcaccgat ttgcgtatgg
    42841 atcgcataag caaaatcaat aggacctgat tcttttggca actcctgaac ggcccctgtc
    42901 ggtgtaaaga cataaatccg ttcagaaaaa atgtcttctt tgaccgaatc cacaaagtcc
    42961 actgcatcac catttgaggc atcttgcaat tctaccagct ctttgatcca gttcatgcca
    43021 acggcttgct cagcttgatt gaccttacca cgcacgcctt ttttataagc ccagtgagca
    43081 gcaaccccgt actcagccac ttgatgcatg tccttagttc tgatttgaat ctcaataggt
    43141 ccttttggtc catacacagt ggtatgaata gactggtagc cattagcttt aggagctgca
    43201 atataatcct tgaagcggcc tggcatggga cgccaaagct cgtgaatata gccaaccata
    43261 gcatagacat cgctttgcgt ttccatgaca caacgaatgg caatcagatc aaaaatctga
    43321 tcgaaacgtt tctttttgtc ccgcattttc cgataaatgg aataaatgtg ttttggtcgg
    43381 ccatacacat ctccaaacaa cccttgttgt gtcgtatagg ttttgacctt actgacaata
    43441 gcctctacca aggcttcacg ctcgcgacgt ttttctttca tcatatggga aattttgtaa
    43501 aattcggttt cattgaggta acgaaaagcc aaatcttcta gttcccattt gatgcgacta
    43561 atccccaaac gatgcgccaa gggggcatag atttccatgg tttcgcgcga aatgcgctct
    43621 tgtttgtcct tgcgcaaatg tttgagggtg cgcatattat gcaggcggtc agccaatttc
    43681 accaaaatca cgcgaatatc tttggacata gccatcagca ttttgcgatg gttttcggcg
    43741 agttgctcct catgagattt gtactcaact ttacctaact tggtgacacc atcaacgata
    43801 tcacgagcat catggccaaa gtctgcttcg atctcatcta aggtaatgtc cgtatcttct
    43861 acgacatcat gtaaaaagcc acaagcaact gtcacagcat ccagatgcaa atcagccaga
    43921 atccccgcca cctgaatcgg atggacgata tagggctcgc ctgactttct cacttggtag
    43981 aaatgggccg ctgttgcata tgctaaagcc tttgccacaa aagccacatc agccttggtc
    44041 atataggtgg ccgctaaggc aatgacttct tctcctgtta cgttcattat ttttgccatt
    44101 tcgttcctca tctagcattt cttttcccta ttttaacact ttacacacaa aagcaaaagg
    44161 cagaatctgc taagaaagcg cttagtgtga ccttttctta gaaaacggtt agtgagctgc
    44221 ttttgatatc ttttgggatc tctcaggtgt gagcatgata ccaaaggcct gctcccgacc
    44281 aaaaatagag agaaccaagg ggctctctct attatgtttg cttatcagta aggcctctca
    44341 attcagagga ttagttgttt tctttgcgtt ttgtaacggc taggacacca gctgttgtca
    44401 tcactgctac tgctgctgct gtaaagaatg ggttggcttg ctcaccagtt gctggtagac
    44461 gtctgtggtt gttggctaca ggtgtcttag ccatattgcc attgcggcgt tctggcgttt
    44521 ggttagcttc tttgtcagca ggtttttctg gagctggagt tacctctttg ctcttttctg
    44581 gagctttttc gcctggttgc tctggcattt ctggcgttgg tgtcacttct gggctctttt
    44641 ctggagcttt tt
//
LOCUS       DAUGUF010000014        41857 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUGUF010000014 DAUGUF010000000
VERSION     DAUGUF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41857
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.014"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..409
                     /locus_tag="VIB71_000755"
     CDS             <1..409
                     /locus_tag="VIB71_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8822505.1"
                     /translation="VLMGGQSESVEFTKDTQTGMSGQTTPQVETEDTKEPGVLMGGQS
                     ESVEFTKDTQTGMSGFSETVTIVEDTRPKLVFHFDNNEPKVEENREKPTKNITPILPA
                     TGDIENVLAFLGILILSVLSIFSLLKNKQNNKV"
     gene            633..1481
                     /locus_tag="VIB71_000756"
                     /pseudo
     CDS             633..1481
                     /locus_tag="VIB71_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407229.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
     gene            1767..4037
                     /locus_tag="VIB71_000757"
     CDS             1767..4037
                     /locus_tag="VIB71_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus ancillary protein 1"
                     /protein_id="HEQ8822506.1"
                     /translation="MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMFLTLVSSMRGA
                     QSIFGEEKRIEEVSVPKIKSPDDAYPWYGYDSYDSSHPYYERFKVAHDLRVNLNGSKS
                     YQVYCFNINSHYPNRKNAFSKQWFKRVDGTGDVFTNYAQTPKIRGESLNNKLLSIMYN
                     AYPKNANGYMDKIEPLNAILVTQQAVWYYSDSSYGNIKTLWASELKDGKIDFEQVKLM
                     REAYSKLISDDLEETSKNKLPQGSKLNIFVPQDKSVQNLLSAEYVPESPPAPGQSPEP
                     PVQTKKTSVIIRKYAEGDYSKLLEGATLRLTGEDILDFQEKVFQSNGTGEKIELSNGT
                     YTLTETSSPDGYKIAEPIKFRVVNKKVFIVQKDGSQVENPNKEVAEPYSVEAYSDMQD
                     SNYINPETFTPYGKFYYAKNKDKSSQVVYCFNADLHSPPESEDGGGTIDPDISTMKEV
                     KYTHTAGSDLFKYALRPRDTNPEDFLKHIKKVIEKGYNKKGDSYNGLTETQFRAATQL
                     AIYYFTDSTDLKTLKTYNNGKGYHGFESMDEKTLAVTKELINYAQDNSAPQLTNLDFF
                     VPNNSKYQSLIGTEYHPDDLVDVIRMEDKKQEVIPVTHSLTVKKTVVGELGDKTKGFQ
                     FELELKDKTGQPIVNTLKTNNQDLVAKDGKYSFNLKHGDTIRIEGLPTGYSYTLKETE
                     AKDYIVTVDNKVSQEAQSASENVTADKEVTFENRKDLVPPTGFITDGGTYLWLLLLVP
                     FGLLVWFFGRKGLKND"
     gene            4030..4551
                     /gene="lepB"
                     /locus_tag="VIB71_000758"
     CDS             4030..4551
                     /gene="lepB"
                     /locus_tag="VIB71_000758"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8822507.1"
                     /translation="MTNYLNRLNENPLFKAFIRLVLKISIIGFLGYILFQYVFGVMIV
                     NTNQMSPAVSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVSFTQEGG
                     LLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALPINQI
                     KGKISTLLRVRGI"
     gene            4573..5601
                     /locus_tag="VIB71_000759"
     CDS             4573..5601
                     /locus_tag="VIB71_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QVPTGV class sortase B protein-sorting
                     domain-containing protein"
                     /protein_id="HEQ8822508.1"
                     /translation="MKKNKLLLATAILATALGTASLNQNVKAETAGVVSSGQLTIKKS
                     ITNFNDDTLLMPKTDYTFSVNPDSAATGTESNLPIKPGIAVNNQDIKVSYSNTDKTSG
                     KEKQVVVDFMKVTFPSVGIYRYVVTENKGTAEGVTYDDTKWLVDVYVGNNEKGGLEPK
                     YIVSKKGDSATKEPIQFNNSFETTSLKIEKEVTGNTGDHKKAFNFTLTLQPNEYYEAS
                     SVVKIEENGQTKDVKIGEAYKFTLNDSQSVILSKLPVGINYKVEEAEANQGGYTTTAT
                     LKDGEKLSTYNLGQEHKTDKTADEIVVTNNRDTQVPTGVVGTLAPFAVLSIVAIGGVI
                     YITKRKKA"
     gene            5617..6342
                     /gene="srtB"
                     /locus_tag="VIB71_000760"
     CDS             5617..6342
                     /gene="srtB"
                     /locus_tag="VIB71_000760"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HEQ8822509.1"
                     /translation="MMMTIVQVINKAIDTLILIFCLVVLFLAGFGLWDSYHLYQQADA
                     SNFKKFKTAQQQPKFEDLLALNEDVIGWLNIPGTHIDYPLVQGKTNLEYINKAVDGSV
                     AMSGSLFLDTRNHNDFTDDYSLIYGHHMAGNAMFGEIPKFLKKDFFNKHNKAIIETKE
                     RKKLTVTIFACLKTDAFDQLVFNPNAITNQDQQRQLVDYISKRSKQFKPVKLKHHTKF
                     VAFSTCENFSTDNRVIVVGTIQE"
     gene            6359..6946
                     /locus_tag="VIB71_000761"
     CDS             6359..6946
                     /locus_tag="VIB71_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HEQ8822510.1"
                     /translation="MRKYWKMLFSVVMILTMLAFNQTVLAKDSTVQTSISVENVLERA
                     GDSTPFSIALESIDAMKTIEEITIAGSGKASFSPLTFTTVGQYTYRVYQKPSQNKDYQ
                     ADTTVFDVLVYVTYDEDGTLVAKVISRRAGDEEKSAITFKPKRLVKPIPPRQPNIPKT
                     PLPLAGEVKSLLGILSIVLLGLLVLLYVKKLKSKL"
     gene            complement(7105..8310)
                     /locus_tag="VIB71_000762"
     CDS             complement(7105..8310)
                     /locus_tag="VIB71_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEQ8822511.1"
                     /translation="MVIFDLKHVQTLHSLSQLPISVMSQDKALIQVYGNDDYLLCYYQ
                     FLKHLAIPQAAQDVIFYEGLFEESFMIFPLCHYIIAIGPFYPYSLNKDYQEQLANNFL
                     KHSSHRSKEELLSYMALVPHFPINNVRNLLIAIDAFFDTQFETTCQQTIHQLLQHSKQ
                     MTADPDIIHRLKHISKASSQLPPVLEHLNHIMDLVKLGNPQLLKQEINRIPLSSITSS
                     SISALRAEKNLTVIYLTRLLEFSFVENTDVAKHYSLVKYYMALNEEASDLLKVLRIRC
                     AAIIHFSESLTNKSISDKRQMYNSVLHYVDSHLYSKLKVSDIAKRLYVSESHLRSVFK
                     KYSNVSLQHYILSTKIKEAQLLLKRGIPVGEVAKSLYFYDTTHFHKIFKKYTGISSKD
                     YLAKYRDNI"
     gene            8695..12180
                     /locus_tag="VIB71_000763"
     CDS             8695..12180
                     /locus_tag="VIB71_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ8822512.1"
                     /translation="MTQKNSYKLSFLLSLTGFILGLLLVFIGLSGVSVGHAETRNGAN
                     KQGSFEIKKVDQNNKPLPGATFSLTSKDGKGTSVQTFTSNDKGIVDAQNLQPGTYTLK
                     EETAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISKAGSKDVSSSLQLENPKMSV
                     VSKYGKTEVSSGAADFYRNHAAYFKMSFELKQKDKSETINPGDTFVLQLDRRLNPKGI
                     SQDIPKIIYDSANSPLAIGKYHAENHQLIYTFTDYIAGLDKVQLSAELSLFLENKEVL
                     ENTSISNFKSTIGGQEITYKGTVNVLYGNESTKESNYITNGLSNVGGSIESYNTETGE
                     FVWYVYVNPNRTNIPYATMNLWGFGRARSNTSDLENDANTSSAELGEIQVYEVPEGEK
                     LPSSYGVDVTKLTLRTDITAGLGNGFQMTKRQRIDFGNNIQNKAFIIKVTGKTDQSGK
                     PLVVQSNLASFRGASEYAAFTPVGGNVYFQNEIALSPSKGSGSGKSEFTKPSITVANL
                     KRVAQLRFKKMSTDNVPLPEAAFELRSSNGNSQKLEASSNTQGEVHFKDLTSGTYDLY
                     ETKAPKGYQQVTEKLATVTVDTTKPAEEMVTWGSPHSSVKVEANKEVTIVNHKETLTF
                     SGKKIWENDRPDQRPAKIQVQLLQNGQKMPNQIQEVTKDNDWSYHFKDLPKYDAKNQE
                     YKYSVEEVNVPDGYKVSYLGNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGSKIIDE
                     DTLTSFKGKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEFKNLKK
                     YNGTGNDIIYSVKEVTVPTGYDVTYSANDIINTKREVITQQGPKLEIEETLPLESGAS
                     GGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFSKRDIDGKELAGATMELR
                     DSSGKTISTWISDGQVKDFYLMPGKYTFVETAAPDGYEIATAITFTVNEQGQVTVNGK
                     ATKGDTHIVMVDAYKPTKGSGQVIDIEEKLPDEQGHSGSTTEIEDSKSSDLIIGGQGE
                     VVDTTEDTQSGMTGHSGSTTEIEDSKSSDVIIGGQGQVVETTEDTQTGMYGDSGCKTE
                     VEDTKLVQSFHFDNKEPESNSEIPKKDKPKSNTSLPATGEKQHNMFFWMVTSCSLISS
                     VFVISLKSKKRLSSC"
     gene            complement(12447..13112)
                     /locus_tag="VIB71_000764"
     CDS             complement(12447..13112)
                     /locus_tag="VIB71_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822513.1"
                     /translation="MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKALTADEKSIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPTEITYEHHY
                     WDGTVHSEKHNNTQWHYDWKSQQTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEEDYKNKWDKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
     gene            13465..14871
                     /locus_tag="VIB71_000765"
     CDS             13465..14871
                     /locus_tag="VIB71_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEQ8822514.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLHSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
     gene            complement(14939..15850)
                     /locus_tag="VIB71_000766"
     CDS             complement(14939..15850)
                     /locus_tag="VIB71_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8822515.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEVKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKTSHLKHYIKHTILDYFTNQRF"
     gene            15971..17155
                     /locus_tag="VIB71_000767"
     CDS             15971..17155
                     /locus_tag="VIB71_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ8822516.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRSAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            17167..17826
                     /locus_tag="VIB71_000768"
     CDS             17167..17826
                     /locus_tag="VIB71_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ8822517.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            17829..18476
                     /locus_tag="VIB71_000769"
     CDS             17829..18476
                     /locus_tag="VIB71_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ8822518.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(18598..19278)
                     /locus_tag="VIB71_000770"
     CDS             complement(18598..19278)
                     /locus_tag="VIB71_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8822519.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            19452..19817
                     /locus_tag="VIB71_000771"
     CDS             19452..19817
                     /locus_tag="VIB71_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ8822520.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            19854..20873
                     /locus_tag="VIB71_000772"
     CDS             19854..20873
                     /locus_tag="VIB71_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEQ8822521.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            21327..21647
                     /locus_tag="VIB71_000773"
     CDS             21327..21647
                     /locus_tag="VIB71_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822522.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKSLADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            21637..23637
                     /locus_tag="VIB71_000774"
     CDS             21637..23637
                     /locus_tag="VIB71_000774"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEQ8822523.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEESHRQQAAQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKQHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            23639..24118
                     /locus_tag="VIB71_000775"
     CDS             23639..24118
                     /locus_tag="VIB71_000775"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEQ8822524.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLISLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            24187..24771
                     /locus_tag="VIB71_000776"
     CDS             24187..24771
                     /locus_tag="VIB71_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEQ8822525.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKGLFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            24787..25785
                     /locus_tag="VIB71_000777"
     CDS             24787..25785
                     /locus_tag="VIB71_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEQ8822526.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLVAALANDLPKERVIERMRPIA"
     gene            25782..26102
                     /locus_tag="VIB71_000778"
     CDS             25782..26102
                     /locus_tag="VIB71_000778"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEQ8822527.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            26303..28078
                     /locus_tag="VIB71_000779"
     CDS             26303..28078
                     /locus_tag="VIB71_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEQ8822528.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGNFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     ESNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFKEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            28079..29494
                     /locus_tag="VIB71_000780"
     CDS             28079..29494
                     /locus_tag="VIB71_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEQ8822529.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            29539..30165
                     /locus_tag="VIB71_000781"
     CDS             29539..30165
                     /locus_tag="VIB71_000781"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEQ8822530.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFADL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLEETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(30285..31547)
                     /locus_tag="VIB71_000782"
     CDS             complement(30285..31547)
                     /locus_tag="VIB71_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEQ8822531.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTHA"
     gene            complement(31560..32438)
                     /locus_tag="VIB71_000783"
     CDS             complement(31560..32438)
                     /locus_tag="VIB71_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822532.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            32876..34168
                     /locus_tag="VIB71_000784"
     CDS             32876..34168
                     /locus_tag="VIB71_000784"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEQ8822533.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLGFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            34495..35538
                     /locus_tag="VIB71_000785"
     CDS             34495..35538
                     /locus_tag="VIB71_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8822534.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSSKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIETAK
                     KAIIEGTITVPEN"
     gene            35711..36250
                     /gene="nusG"
                     /locus_tag="VIB71_000786"
     CDS             35711..36250
                     /gene="nusG"
                     /locus_tag="VIB71_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEQ8822535.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            36621..37976
                     /gene="nga"
                     /locus_tag="VIB71_000787"
     CDS             36621..37976
                     /gene="nga"
                     /locus_tag="VIB71_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEQ8822536.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFVSPM
                     RIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            37981..38466
                     /locus_tag="VIB71_000788"
     CDS             37981..38466
                     /locus_tag="VIB71_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEQ8822537.1"
                     /translation="MYKVPKSLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMVHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            38490..40205
                     /gene="slo"
                     /locus_tag="VIB71_000789"
     CDS             38490..40205
                     /gene="slo"
                     /locus_tag="VIB71_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEQ8822538.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRS
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            40460..40867
                     /locus_tag="VIB71_000790"
     CDS             40460..40867
                     /locus_tag="VIB71_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822539.1"
                     /translation="MKQQSYQPLRFVYLLVALFAAMLLIARPVMADGENNDPANAAYY
                     KGKSAGKEASWTDLTPTNPTIPEPPSDIRETTNKQHYKDGYTDGYRDGYNEGWKSQHP
                     VLTPVKVIWDLISHWLQQFFPNNQATTTVQSMS"
     gene            complement(41053..41289)
                     /locus_tag="VIB71_000791"
     CDS             complement(41053..41289)
                     /locus_tag="VIB71_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822540.1"
                     /translation="MKKKLSLFMIATAAVVSLSLATPENQTVSANDTQVTCVGCPDCG
                     PKWSCCPLTCMRDLLRGWGKSAAYYCTWGYYYSE"
     gene            complement(41699..>41857)
                     /locus_tag="VIB71_000792"
     CDS             complement(41699..>41857)
                     /locus_tag="VIB71_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822541.1"
                     /translation="KLSLFMIATAAVAGLSLATLGSHQTVSANDASYSNGFYGHTGPD
                     SWLLYTVW"
BASE COUNT        13397 a         7171 c         8727 g        12562 t
ORIGIN      
        1 agtgttgatg ggaggccaaa gtgagtctgt tgaatttact aaagacactc aaacaggcat
       61 gagtggtcaa acaactcctc aggttgagac agaagacacg aaagagccag gagtgttgat
      121 gggaggtcaa agtgagtctg ttgaatttac taaagacact caaacaggca tgagcggttt
      181 cagtgaaaca gtgaccattg ttgaagatac gcgtccgaag ttagtgttcc attttgacaa
      241 taatgagccc aaagtggaag agaatcggga aaagcctaca aaaaatataa cacctatcct
      301 tcctgcaaca ggagatattg agaatgtttt ggcctttctt ggaatcctta ttttgtcagt
      361 actttctatt tttagccttt taaaaaacaa acaaaacaat aaagtctgac gtaaaagtgt
      421 tccataagaa ataatgcgca aatatgctga atagtggata actgctacag tcaagacaag
      481 tgttaattca aaaggtacta cttatacatc gtataataga cttacaagaa atcaagttat
      541 tgttaaacgt cgtaaagctt aacgctttca aaagtcgaaa tcaatcgaga ctgtctttag
      601 gcagtctcga tttttattga taaggaactg caatgacaga aagactaaaa aatctaggga
      661 tactcttatt atttttattg ggaacagcca tttttcttta ccctacgcta agtagtcagt
      721 ggaatgccta tcgtgatcgt caattgttat caacttatca caaacaagtg actcaaaaga
      781 agccctcaga aatggaggag gtgtggcaaa aggctaaggc gtataacgct aggcttggga
      841 ttcagcccgt tccagatgct ttttcattta gggatggcat tcatgataaa aactacgaaa
      901 gcctacttca aattgaaaac aatgatatta tgggataagt tgaagtgccc tctattaaag
      961 tgacgttacc catataccac tatacgacag acgaggtgct aactaaggga gcaggtcact
     1021 tagttggaag tgccttacca gttggtggcg acgggactca cacggttatt tctgctcata
     1081 gaggccttcc atcggcagaa atgtttacta atttgaattt agtgaaaagg ggagatacct
     1141 tttactttcg tgtgttaaat aaagtattgg cttataaagt tgatcagata ctaactgttg
     1201 aaccagatca agtcacatct ctttctgggg taatgggaaa agatcatgct actctggtta
     1261 cctgcacacc atatggtgtt aataccaagc gtctattggt cagaggtcat agaattacat
     1321 atcattacaa aaagtatcaa caggctaaaa aagcaatgaa actcgtggat aaatcaagaa
     1381 tgtggacaga agtagtgtgt gctgctttcg gggtggttat agctattatt ttagtattta
     1441 tgtattcaaa gatgactgat aaaaaagtga ttaaaaacta acttgccctg aaccttcttt
     1501 atcgtattga aactgtcata aaagtaaaat aatctggtag ttactatccc ctttgatgaa
     1561 gtttaattaa atctcatcaa gagaaaaata ttaggcgatt acaaatgatt ttcccaaaaa
     1621 ttattttttg gaacgcataa tatggaaaaa aagatgataa gaacaactgt tttaaacatc
     1681 aaataaatga tatagtagct atgaaatagc attgtgactg tccggtaaag ggatgggact
     1741 gaagatttta ttcagaagga gagggaatga ataacaaaaa attgcaaaag aagcaagatg
     1801 ctcctcgggt atcaaacaga aagccaaaac aattaactgt cactttagtg ggagtatttt
     1861 taatgttttt gaccttggta agttccatga gaggtgctca aagcatattt ggagaggaaa
     1921 agagaattga agaagtcagt gttcctaaaa taaaaagtcc agatgatgcc tacccttggt
     1981 atggctatga ttcatatgac tctagtcatc cttactatga acgttttaaa gtagcacatg
     2041 atttaagggt taatttaaat ggaagtaaga gctaccaagt atattgcttt aatatcaatt
     2101 ctcattatcc gaatagaaaa aatgcttttt ctaaacaatg gtttaagaga gttgatggga
     2161 caggtgatgt gttcacaaat tatgctcaga cacctaagat tcgtggagaa tcattgaata
     2221 ataaactttt aagtattatg tacaacgctt atcctaaaaa tgctaatggc tatatggata
     2281 agatagaacc attaaatgct attttagtaa ctcaacaagc tgtttggtac tattctgaca
     2341 gttcttatgg taatataaaa acgttatggg catctgagct taaagacgga aaaatagatt
     2401 ttgaacaagt aaaattaatg cgtgaagctt actcaaaact aattagtgat gatttagaag
     2461 aaacatctaa aaataagcta cctcaaggat ctaaactgaa tatttttgtt ccgcaagata
     2521 aatctgttca aaatttatta agtgcagagt acgtgcctga atcccctccg gcaccaggtc
     2581 agtctccaga accgccagtg caaacaaaaa aaacatcagt cattatcaga aaatatgcgg
     2641 aaggtgacta ctctaaactt ctagagggag caactttgcg tttaacaggg gaagatatcc
     2701 tagattttca agaaaaagtc ttccaaagta atggaacagg agaaaagatt gaattatcaa
     2761 atgggactta taccttaaca gaaacatcat ctccagatgg atataaaatt gcggagccga
     2821 ttaagtttag agtagtgaat aaaaaagtat ttatcgtcca aaaagatggt tctcaagtgg
     2881 aaaatccaaa caaagaagta gcagagccat actcagtgga agcgtacagc gatatgcaag
     2941 atagtaacta tattaatcca gaaacgttca ctccttatgg gaaattttat tacgctaaaa
     3001 ataaggataa aagttcacaa gttgtctact gttttaatgc tgatttacac tctccacctg
     3061 aatcagagga tgggggagga actatagatc ctgatattag tacgatgaaa gaagtcaagt
     3121 acacacatac ggcaggtagt gatttgttta aatacgcgct aagaccgaga gatacaaatc
     3181 cagaagactt cttaaagcac attaaaaaag taattgaaaa aggctacaat aaaaaaggtg
     3241 atagctataa tggattaaca gaaacacagt ttcgcgcggc tactcagctt gctatctatt
     3301 actttacaga cagcactgac ttaaaaacct taaaaactta taacaatggg aaaggttacc
     3361 atggatttga atctatggat gaaaaaaccc tagctgtaac aaaagaatta attaattacg
     3421 ctcaagataa tagtgcccct caactaacaa atcttgattt cttcgtacct aataatagca
     3481 aataccaatc tcttattggg acagaatacc atccagatga tttggttgac gtgattcgta
     3541 tggaagataa aaagcaagaa gttattccag taactcacag tttgacagtg aaaaaaacag
     3601 tagtcggtga gttgggagat aaaactaaag gcttccaatt tgaacttgag ttgaaagata
     3661 aaactggaca gcctattgtt aacactctaa aaactaataa tcaagattta gtagctaaag
     3721 atgggaaata ttcatttaat ctaaagcatg gtgacaccat aagaatagaa ggattaccga
     3781 cgggatattc ttatactctg aaagagactg aagctaagga ttatatagta accgttgata
     3841 acaaagttag tcaagaagct caatcagcaa gtgagaatgt cacagcagac aaagaagtca
     3901 cttttgaaaa ccgtaaagat cttgtcccac caactggttt tattactgat ggtggaacct
     3961 atctgtggtt attattgctt gtcccatttg gtttgttagt gtggttcttt ggtcgtaaag
     4021 gactaaaaaa tgactaatta cctaaatcgc ttaaatgaga atccactatt taaagctttc
     4081 atacggttag tacttaagat ttctattatt ggatttctag gttacatttt atttcagtat
     4141 gtttttggcg tcatgattgt taacacaaat cagatgagtc ctgctgtaag tgctggtgat
     4201 ggagtcttat attatcgttt gactgatcgc tatcatatta atgatgtggt ggtctatgag
     4261 gttgataaca ctttgaaagt tggtcgaatt gccgctcaag ctggcgatga ggttagtttt
     4321 acgcaagaag gaggactgtt gattaatggg catccaccag aaaaagaggt cccttacctg
     4381 acgtatcctc actcaagtgg tccaaacttt ccctataaag ttcctacggg tacgtatttc
     4441 atattgaatg attatcgtga agaacgtttg gacagtcgtt attatggggc gttacccatc
     4501 aatcaaatca aagggaaaat ctcaactcta ttaagagtga gaggaattta aaaaaatttg
     4561 gagagagaga aaatgaaaaa aaataaatta ttacttgcta ctgcaatctt agcaactgct
     4621 ttaggaacag cttctttaaa tcaaaacgta aaagctgaga cggcaggggt tgttagcagt
     4681 ggtcaattaa caataaaaaa atcaattaca aattttaatg atgatacact tttgatgcct
     4741 aagacagact atacttttag cgttaatccg gatagtgcgg ctacaggtac tgaaagtaat
     4801 ttaccaatta aaccaggtat tgctgttaac aatcaagata ttaaggtttc ttattctaat
     4861 actgataaga catcaggtaa agaaaaacaa gttgttgttg actttatgaa agttactttt
     4921 cctagcgttg gtatttaccg ttatgttgtt accgagaata aagggacagc agaaggagtt
     4981 acatatgatg atacaaaatg gttagttgac gtctatgttg gtaataatga aaagggaggt
     5041 cttgaaccaa agtatattgt atctaaaaaa ggagattctg ctactaaaga accaatccag
     5101 tttaataatt cattcgaaac aacgtcatta aaaattgaaa aggaagttac tggtaataca
     5161 ggagatcata aaaaagcatt taactttaca ttaacattgc aaccaaatga atactatgag
     5221 gcaagttcgg ttgtgaaaat tgaagagaac ggacaaacga aagatgtgaa aattggggag
     5281 gcatataagt ttactttgaa cgatagtcag agtgtgatat tgtctaaatt accagttggt
     5341 attaattata aagttgaaga agcagaagct aatcaaggtg gatatactac aacagcaact
     5401 ttaaaagatg gagaaaagtt atctacttat aacttaggtc aggaacataa aacagacaag
     5461 actgctgatg aaatcgttgt cacaaataac cgtgacactc aagttccaac tggtgttgta
     5521 ggcacccttg ctccatttgc agttcttagc attgtggcta ttggtggagt tatctatatt
     5581 acaaaacgta aaaaagctta agtgattagt caaagaatga tgatgacaat tgtacaggtt
     5641 atcaataaag ccattgatac tctcattctt atcttttgtt tagtcgtact atttttagct
     5701 ggttttggtt tgtgggattc ttatcatctc tatcaacaag cagacgcttc taatttcaaa
     5761 aaatttaaaa cagctcaaca acagcctaaa tttgaagact tgttagcttt gaatgaggat
     5821 gtcattggtt ggttaaatat cccggggact catattgatt atcctctagt tcagggaaaa
     5881 acgaatttag agtatattaa taaagcagtt gatggcagtg ttgccatgtc tggtagttta
     5941 tttttagata cacggaatca taatgatttt acggacgatt actctctgat ttatggccat
     6001 catatggcag gtaatgccat gtttggcgaa attccaaaat ttttaaaaaa ggattttttc
     6061 aacaaacata ataaagctat cattgaaaca aaagagagaa aaaaactaac cgtcactatt
     6121 tttgcttgtc tcaagacaga tgcctttgac cagttagttt ttaatcctaa tgctattacc
     6181 aatcaagacc aacaaaggca gctcgttgat tatatcagta aaagatcaaa acaatttaaa
     6241 cctgttaaat tgaagcatca tacaaagttc gttgcttttt caacgtgtga aaatttttct
     6301 actgacaatc gtgttatcgt tgtcggtact attcaagaat aacgaaagga ggagactttt
     6361 gagaaaatat tggaaaatgt tattttctgt cgtaatgata ttaaccatgc tggcctttaa
     6421 tcagactgtt ttagcaaaag acagcactgt tcaaactagc attagtgtcg aaaatgtctt
     6481 agagagagca ggcgatagta ccccattttc gattgcatta gaatcaattg atgcgatgaa
     6541 aacaatagaa gaaataacaa ttgctggttc tggaaaagca agcttttccc ctctgacctt
     6601 cacaacagtt gggcaatata cttatcgtgt ttatcagaag ccttcacaaa ataaagatta
     6661 tcaagcagat actactgtat ttgacgttct tgtctatgtg acctatgatg aagatgggac
     6721 tctagtcgca aaagttattt ctcgaagggc tggagacgaa gaaaaatcag cgattacttt
     6781 taagcccaaa cggttagtaa aaccaatacc gcctagacaa cctaacatcc ctaaaacccc
     6841 attaccatta gctggtgaag taaaaagttt attgggtatc ttaagtatcg tattactggg
     6901 gttactagtt cttctttatg ttaaaaaact gaagagtaag ctataaaacc catttttaag
     6961 agtcacacat ttttagttgc tctattttta taatgaaact tattgacatc ttcatagtct
     7021 tgcttgactt tggagatgtt ttctatgctg ataggttttt gtaccatata agataatgat
     7081 tgatgaaaag agtgtcttga attcttaaat attatctcgg tatttagcaa gatagtcttt
     7141 tgaagaaata cccgtgtatt ttttaaagat tttatgaaaa tgggtagtgt cataaaaata
     7201 taagctttta gccacttctc caacaggaat tcctcgtttt aagagtagtt gagcttcttt
     7261 gatttttgta cttagaatat aatgttgtaa ggaaacattt gagtattttt taaagactga
     7321 acgtaagtga gattcggaaa catataggcg cttagcgata tcagatacct ttaatttgga
     7381 atacaggtga ctatcgacat aatgaagcac actattgtac atttgacgtt tatcagaaat
     7441 acttttattg gttaatgatt cggaaaaatg gatgatggct gcacagcgaa ttctcaaaac
     7501 tttgagcaag tcactcgctt cttcatttaa ggccatgtag tatttgacaa ggctataatg
     7561 ctttgctacg tcagtatttt ctacaaaact gaattccagt aacctagtta aatagataac
     7621 agtgaggttc ttttccgccc ttagagcaga aatagaagat gaggtgatac ttgataaggg
     7681 gatgcgattg atttcttgct tgagcaattg tggattgcct agctttacca gatccataat
     7741 atgatttagg tgctctaaaa caggcggtag ttggctagat gctttgctaa tatgcttaag
     7801 gcgatgaatg atatcaggat cagcagtcat ctgttttgaa tgctgcaaca attgatgaat
     7861 tgtttgttgg caagtcgtct caaattgtgt gtcaaaaaaa gcgtcaatag ctatcaaaag
     7921 gttccgcaca ttattaattg gaaaatgtgg gacaagtgcc atataggata agagctcttc
     7981 tttgctacga tgagaagaat gttttaaaaa attattagct aattgttcct gatagtcttt
     8041 attaagtgaa taagggtaga aaggtccaat ggcaataatg tagtgacaaa gaggaaaaat
     8101 cataaaggac tcttcaaata aaccctcata aaaaataaca tcttgtgcag cttgaggaat
     8161 agctagatgc tttaaaaatt gatagtaaca taataaatag tcgtcattac catatacttg
     8221 aataagtgcc ttatcttgtg acatcactga aataggtaat tgagacaagc tgtgtaatgt
     8281 ttgcacatgt tttaaatcga atataaccat ttgatagatt gccccccatc cttagttgta
     8341 tcattttcct tagacttgta aaagctttag taaatgttaa tggtgaaaat tcctatttgg
     8401 taggcacact aaaaggtctt cctaatagta aactctctct ccatcatctc ctgccttaat
     8461 tatactatga atagctaagc agataaagat aaaggatttg tacgttaagc gcttgaaaaa
     8521 gaaagagtta cagataatga cataaaaaac gctaaaaaac catcaaaata aatactctga
     8581 ccataagatg tagacttgac aactgaaaat ggtaaaataa ctatttgaca gttggcctgt
     8641 agtctttagt tttggacata ggctgtcgct tatgaatgtg gagagagaaa ataaatgaca
     8701 caaaaaaata gctataagtt aagcttcctg ttatccctaa caggatttat tttaggttta
     8761 ttattggttt ttataggatt gtccggagta tcagtaggac atgcggaaac aagaaatgga
     8821 gcaaacaaac aaggatcttt tgaaatcaag aaagtcgacc aaaacaataa gcctttaccg
     8881 ggagcaactt tttcactgac atcaaaggat ggcaagggaa catctgttca aacgttcact
     8941 tcaaatgata aaggtattgt agatgctcaa aatctccaac cagggactta taccttaaaa
     9001 gaagaaacag caccagatgg ttatgataaa accagccgga cttggacagt gactgtttat
     9061 gagaacggct ataccaagtt ggttgaaaat ccctataatg gggaaatcat cagtaaagca
     9121 gggtcaaaag atgttagtag ttctttacag ttggaaaatc ccaaaatgtc agttgtttct
     9181 aaatatggga aaacagaggt tagtagtggc gcagcggatt tctaccgcaa ccatgccgcc
     9241 tattttaaaa tgtcttttga gttgaaacaa aaggataaat ctgaaacaat caacccaggt
     9301 gatacctttg tgttacagct ggatagacgt ctcaatccta aaggtatcag tcaagatatc
     9361 cctaaaatca tttacgacag tgcaaatagt ccgcttgcga ttggaaaata ccatgctgag
     9421 aaccatcaac ttatctatac tttcacagat tatattgcgg gtttagataa agtccagttg
     9481 tctgcagaat tgagcttatt cctagagaat aaggaagtgt tggaaaatac tagtatctca
     9541 aattttaaga gtaccatagg tgggcaggag atcacctata aaggaacggt taatgttctt
     9601 tatggaaatg agagcactaa agaaagcaat tatattacta atggattgag caatgtgggt
     9661 gggagtattg aaagctacaa caccgaaacg ggagaatttg tctggtatgt ttatgtcaat
     9721 ccaaaccgta ccaatattcc ttatgcgacc atgaatttat ggggatttgg aagggctcgt
     9781 tcaaatacaa gcgacttaga aaacgacgct aatacaagta gtgctgagct tggagagatt
     9841 caggtctatg aagtacctga aggagaaaaa ttaccatcaa gttatggggt tgatgttaca
     9901 aaacttactt taagaacgga tatcacagca ggcctaggaa atggttttca aatgaccaaa
     9961 cgtcagcgaa ttgactttgg aaataatatc caaaataaag catttatcat caaagtaaca
    10021 gggaaaacag accaatctgg taagccattg gttgttcaat ccaatttggc aagttttcgt
    10081 ggtgcttctg aatatgctgc ttttactcca gttggaggaa atgtctactt ccaaaacgaa
    10141 attgccttgt ctccttctaa gggtagtggt tctgggaaaa gtgaatttac taagccctct
    10201 attacagtag caaatctaaa acgagtggct cagcttcgct ttaagaaaat gtcaactgac
    10261 aatgtgccat tgccagaagc ggcttttgag ctgcgttcat caaatggtaa tagtcagaaa
    10321 ttagaagcca gttcaaacac acaaggagag gttcacttta aggacctgac ctcgggcaca
    10381 tatgacctgt atgaaacaaa agcgccaaaa ggttatcagc aggtgacaga gaaattggcg
    10441 accgttactg ttgatactac caaacctgct gaggaaatgg tcacttgggg aagcccacat
    10501 tcgtctgtaa aagtagaagc taacaaagaa gtcacgattg tcaaccataa agaaaccctt
    10561 acgttttcag ggaagaaaat ttgggagaat gacagaccag atcaacgccc agcaaagatt
    10621 caagtgcaac tgttgcaaaa tggtcaaaag atgcctaacc agattcaaga agtaacgaag
    10681 gataacgatt ggtcttatca cttcaaagac ttgcctaagt acgatgccaa gaatcaggag
    10741 tataagtact cagttgaaga agtaaatgtt ccagacggct acaaggtgtc gtatttagga
    10801 aatgatatat ttaacaccag agaaacagaa tttgtgtttg aacagaataa ctttaacctt
    10861 gaatttggaa atgctgaaat aaaaggtcaa tctgggtcaa aaatcattga tgaagacacg
    10921 ctaacgtctt tcaaaggtaa gaaaatttgg aaaaatgata cggcagaaaa tcgtccccaa
    10981 gccattcaag tgcagcttta tgctgatgga gtggctgtgg aaggtcaaac caaatttatt
    11041 tctggctcag gtaatgagtg gtcatttgag tttaaaaact tgaagaagta taatggaaca
    11101 ggtaatgaca tcatttactc agttaaagaa gtaactgttc caacaggtta tgatgtgact
    11161 tactcagcta atgatattat taataccaaa cgtgaggtta ttacacaaca aggaccgaaa
    11221 ctagagattg aagaaacgct tccgctagaa tcaggtgctt caggcggtac cactactgtc
    11281 gaagactcac gcccagttga taccttatca ggtttatcaa gtgagcaagg tcagtccggt
    11341 gatatgacaa ttgaagaaga tagtgctacc catattaaat tctcaaaacg tgatattgac
    11401 ggcaaagagt tagctggtgc aactatggag ttgcgtgatt catctggtaa aactattagt
    11461 acatggattt cagatggaca agtgaaagat ttctacctga tgccaggaaa atatacattt
    11521 gtcgaaaccg cagcaccaga cggttatgag atagcaactg ctattacctt tacagttaat
    11581 gagcaaggtc aggttactgt aaatggcaaa gcaactaaag gtgacactca tattgtcatg
    11641 gttgatgctt acaagccaac taagggttca ggtcaggtta ttgatattga agaaaagctt
    11701 ccagacgagc aaggtcattc tggttcaact actgaaatag aagacagtaa atcttcagac
    11761 cttatcattg gcggtcaagg tgaagttgtt gacacaacag aagacacaca aagtggtatg
    11821 acgggccatt ctggctcaac tactgaaata gaagatagca agtcttcaga cgttatcatt
    11881 ggtggtcagg ggcaggttgt cgagacaaca gaggataccc aaactggcat gtacggggat
    11941 tctggttgta aaacggaagt cgaagatact aaactagtac aatccttcca ctttgataac
    12001 aaggaaccag aaagtaactc tgagattcct aaaaaagata agccaaagag taatactagt
    12061 ttaccagcaa ctggtgagaa gcaacataat atgttctttt ggatggttac ttcttgctca
    12121 cttattagta gtgtttttgt aatatcacta aaatccaaaa aacgcctatc atcatgttaa
    12181 gataagctgt tggtgacaat agcgaaaaag ggtccactta ttagtgggcc tctttttctg
    12241 gaatcgatcg tctcggttca ctagataagt cattttaagt agttcaaaaa ggccgagcct
    12301 taaaaggttt tctgcctttt taatcttgtt gggtacttac gaaagtattt cggccacttc
    12361 aagcataata cagtcagagt ctgagcaatc atgttgtctc agactctgac tgtattatgc
    12421 aaaagatgat ggactggcag cttcatttac tcaccgaact cccctttata acttgggaat
    12481 gatgctgcta atgggttgtt ttgtttaatg cctgctataa acggtaattt atcccattta
    12541 tttttataat cttcttcaag ctcagtttta aacttccaaa ccattttatg agaaaaataa
    12601 gtgtgtgatt gacggccata ggtgtctact aaaacgtgag aaaattttcc gtcgtttttt
    12661 agtttgtaaa atttatctag agaaggactc cagccagtat aaccagggaa tttatcaaat
    12721 tcttgattaa aatttgtttg ttggcttttc caatcataat gccattgtgt attattgtgt
    12781 ttttcagaat gaactgtacc gtcccaataa tgatgctcat aagttatctc tgtaggagct
    12841 tttacaccct taggaagaaa aactgagaaa tcagggtaaa cccattgttc tttagctgaa
    12901 ttaaaggtta cagtccattc gatacttttt tcatctgcag ttaatgcttt agtatagtcg
    12961 acatagttat caacatagta atttccctgc cagtaaaggt gcactttacc tttctcatca
    13021 atgttatcat gggcatgtac tgatttatac gaactaaaca gcatcgaagc tgctagtagt
    13081 gaagtgaaga gatatttatt acatcgtttc atatcatgaa aaacctttct tttaatacta
    13141 atatattata tcaaaaaaac taaaaagtaa attatttttt aattttttat cataattatt
    13201 taattattta attataacaa agacattgtt gatgagtgaa gcgccattct ttttgctata
    13261 aataagggtt atggaagcaa taaaaaaatc atagttgttt gtttatgaaa acgttatcat
    13321 aataaaaagg gaacaaaagt gttttttgtg ggtttaaact tattgataac taaatgaact
    13381 aaagaaacgc ttattaatat tatcgatagg ttactgatca aaagaacaaa agtgcttgtg
    13441 gacaatgtga aaggaattga caacatgaat aacatcaaaa ccaaaaaaag gtttatggat
    13501 cgctatattg atggctttat gaaatggatg ccagaatcgc tttttatctg ttttatttta
    13561 acctttttag tcgttactat gtctgtgttg atgacggata gtccctttat tggtacggaa
    13621 aagacgggcg ggattatcta tggctgggta aatggttttt gggggctgtt gtcctttgcc
    13681 atgcagatga ctattttact tgcgacaggg aatgctgtag cgagttctcc acctgctcat
    13741 aaaatgttta agtcccttgc caaactgcct caaaccagga ctcagatttt tattttttct
    13801 attgtagtag gttctatctt tggcttttta cactggggtc ttggtatgat ggttgccatt
    13861 gtgtttggga aagagttgct tgttcaggct aggcaaaaag ggattaaggt gcatacacct
    13921 ttgtttgttg ctactttatt ttttaccttt ttaccagcta cttctggttt atctggtgct
    13981 gcggtgcttt attcggctac tccagattat ttgcgaaata gtgtcgcaga tgcttataaa
    14041 caggttgttc ctgaaagtgt tcctctgaca gaatcagttt tgaatcttcc atttatcagt
    14101 cttttagtgg tgtgtatgct ggtaccgctt tgctttgctt tattggcgca cccaaaagat
    14161 gaaactaaaa tcatggaact tgatgatgag atctatcacc atagtcttga taccgcttca
    14221 catgttgtta ttgcaagaaa cacacctgct gagaagatga acgcatctcg cttagtgatg
    14281 tatcttgttg gtggggccat tgttagctat agcctttatc atttttcggt ggtgggcttg
    14341 tctggtctag atctcaatag ttttaacttt ttatttttag gcttagggtt gcttctttgt
    14401 ggtcaacaag gaccagaata ttatggttcc ctattcaaag atggggtcat gtcatcttgg
    14461 ggcttggtgc ttcagtttcc attttacgct ggtatttttg gaatcattca aagtacaggt
    14521 ctaggactag agatttccca tttctttgtc gctatttcaa atgggacaac atggccggtc
    14581 tttgcttatc ttcactcggc tttgctgaat attgcggtac catcaggagg ctcaaaattt
    14641 gtgattgaag ctccctatat cgtccctgca accatcgaag ttggtaatga cctaggtaag
    14701 attttgcagg cttatcaatt aggagatgcc acaacaaact tgatagttcc tttttgggcc
    14761 ttatcttacc tctcaaactt caaactaaaa ttcaatcaaa ttgtggctta tactattcct
    14821 tgtgtcttgg tggtcacagg tattgccatc atttacctat ttgtatttta ggaaataact
    14881 atatgaaacg cttgggattg tttccttcag gtgttttttt aaggtctgag tcaagcaatt
    14941 agaagcgctg gttcgtgaaa taatctaaga tggtgtgctt gatataatgt tttaaatggc
    15001 ttgttttatt gtgcttgaga gaggctagaa caacttccca ttttggatgt tcggtcagtt
    15061 ggacctccac taaaccgtcc atatgagcaa aatgagtaat aggccttggt aggattgtta
    15121 ggtaagagga atagcgcgtg caatttaata aaaaatccca cgaggcagaa taacatttga
    15181 ctacaggaag actatttgct tcttcaaata aggtggtaag ctgatgatta atcataaagg
    15241 ttttatcaaa agttactaag ttttgacgat gtaatgcttt gatagagatg ttaggattac
    15301 tatcaaacgt ctcttgaaag gttttgtgac tcatataaag gcagagttga tctcttagga
    15361 gaatgtcgat atcagcaata gtagcatcta gtgtagtggg tgttaataaa atcgcaaaat
    15421 cgacttcttt tagaaacagt tttttttgca gttcataagc acccgtttct acaatatgaa
    15481 atttaacttc gggattttct tcgatgagtt ttggaatgag ctcagaaaaa acaatgccag
    15541 agatgagttg aggaataccg attgaaattt ctcctttgta ttttttggat tcactccgca
    15601 aatcagccat taattgctca tgtgatgcga taaccacctt agcattttca aaaaagcgtt
    15661 cgccgactga ggttagtcca actagacgcc ctttttgacg ctggaataaa acgactcctt
    15721 cttctttttc gatagtcttg atataactac taagggcggg ttgcgaaata tgactttttt
    15781 gggctgcttt ggttaagtta aagtcacaat taacaatctc aataaaataa gccaagcttg
    15841 aaatattcat attttcctct ttcgataacg tttagttata gcatatataa aaaaacgata
    15901 tttgtttatt atagttcaca ttatataata aaaatgtaag cgtttcaata atgaaaaagg
    15961 agaagtttct atgactaaag aagtggtgat cacatctgct tatcgtaccc cgataggaaa
    16021 ttttggagga gtctttaaat ctttatcagc cgtagatttg ggggtgacag ttgttacaaa
    16081 aattttagct gataccggtc ttaaaagtga tgccattgat gaagtgatct ttgggaatgt
    16141 gttacatgca ggtctgggtc aaaatgttgc tcggcaagta gcgctaaatg cggggctttc
    16201 ttatgatacc cctgctttta cgattgatat ggtctgtggt tctggcttaa aagcagttga
    16261 gttaggtgct caaaagattc aaacgggcaa cgctgatatt gttttagtcg gtggtaccga
    16321 aaacatgagt caagcacctt acgttttaca aggccaacgt tggggatctc gtatgggaga
    16381 tagtaaagta gtagatacca tgcttaaaga tgggttgagt gatgcttttg caggttatca
    16441 catgggtata acagccgaaa atattgtgca acagtatgga ctgaccagag aagaacaaga
    16501 tgcctttgca gctgatagcc aacgtaaagc ccaacttgcc atagaaaaag gtcgtttcaa
    16561 agaagagatt gcacctgtca ctattcctca gcgtaaaggt gaacctttac tcgttgatca
    16621 agatgaatac cctaaatttg gaacgacagt ggataagtta gcaaagttac gctctgcttt
    16681 tatcaaagat gaggggacag taactgctgg taatgcttca ggaatcaatg atggagcagc
    16741 ggcaatttta ttgatgagta aagaaaaagc tgaagaatta gggctcccta ttttagctaa
    16801 aatcactagt tatgcaagtg caggtgtaga cccaagtatt atgggctgcg gaccaatacc
    16861 tgctacgaaa aaggctcttg caaaggctca gctgacaatt gatgacattg atttgattga
    16921 agcaaacgaa gcttttgctg ctcaggcttt agcggtttca cgagaccttg gttttgacaa
    16981 tgaaaaagtt aatgtcaatg gaggagctat tgctttgggt cacccgattg gagcatcagg
    17041 tgctcgtatt ttagtcacct tattagcaga aatggctaag cgtgatgtga gacatggatt
    17101 agcaacgctt tgtattggtg gtggccaagg tcaaagtatc atcgtaacaa gatagaaggt
    17161 aaccgtatga aagagaataa aagaatagca atagcagaag ctatcagtca tattaaagat
    17221 ggtgacacga ttatggtcgg tggttttatg gctaatggaa caccagaagc gttaattgat
    17281 gcactggttg acaaaggcac aaaagactta accttgatct gtaatgatgc tggttttgtt
    17341 gatcgtggtg ttggaaaaat ggtggctaat catcaattca aaaccatcta tgcaacacat
    17401 attggattaa ataaagaagc tgggcgccaa atgactgccg gtgaaacgac gattgagctc
    17461 attcctcaag gaaccttcgc cgaaaaaatt cgcatcggag cttatggcat tggtggcttt
    17521 tacacgccaa caggggtagg aaccttagtg gcagaaggca aggaaacaaa aaccatcaag
    17581 ggaaaaactt atctcttaga atacccattt gaagcagatg tcgccttgat atttgctaat
    17641 aaagctgatg aaatgggaaa tttacagtat agtggttctg aaaataattt taatcaattg
    17701 atggcagctt gtgcaaaaac aacaattgtt caggcgcgag aaatagtacc agtcggcacc
    17761 atacaaccag aatgcgttca tacaccacac atttttgtag attacattgt taaagaagga
    17821 gtatagttat ggcggttgca ttaagtaaag aagagattca aaatcgtatt gcaaagcgtg
    17881 tggccaaaga attagaagat ggtactttgg taaatttagg tattggtcta ccaaccaaag
    17941 tagcgaattt tgtgcctgaa gaaatgacag tgtattttca atctgaaaat gggtttattg
    18001 gactaggtcc taagtcagat gatccgaatt cgactatcgt taatgcagga ggacagcctg
    18061 tgacggttta tccaggagcc gctttcttta atagtgcaga ttcttttggc attatacgtg
    18121 gtggtcatgt tgatttgacc gtcttgggtg ctttagaaat tgcagaaaat ggagatatcg
    18181 ccaattacct gattccaggc aaaatggttc ctggtatggg aggagcgatg gatttattag
    18241 ttggtgctaa aaaagtcatc gtagctatgg agcataccaa taaaggaaag cataagctcc
    18301 taaaagaatg taccttacct ttaacagcaa aaggtgtggt tgaccttatt atcacagaaa
    18361 tgggtgtgtt taaagtaacg ccagatggta tccaagtaat tgaaatcagt gaagggttta
    18421 cttttgatga ggttcaagct gcgacaggtg tacctctaag catagctgaa ggttaatgac
    18481 cagtagcctt ttcttgccat aaaggcatat tgagtaaaaa aaacgtcagt catcggtata
    18541 tcagagattg tgatgcttat ctgaaatact tttaactggc gttttatggt gatttggtta
    18601 ttgatcggct tcaatttttt taaggtagcg gtaaacactt ggttcggaaa tacatagaat
    18661 atcagcgact tttgagacgg ctccttttag ttgaaagact cctttttcat aaagcttggc
    18721 aacaatgtct attttgacat cttggctaag atgtacattg tgtctcagta acgagggatc
    18781 aataatttga ccgataatat cttggatgtt agaggttaaa atttcaacag cttcttctgg
    18841 ctggggtgtg actgttttag gttctttagc agttgggatg aaatgttcta aattgagatt
    18901 gacaagtttt aagaggtccc tagctactcc ttgataggct gaaatatcta agttaataca
    18961 tagcattccc tcgagattac cctttttatc tttaataaaa aaagtagatc cccgaacttc
    19021 tttgtgctga ggactaacga ttgctttgta attggtcaca aaatcttttt ccttatagac
    19081 tttattggta atcaaatcaa gagcaaaggt ggtgagagga gactgtttag accgtccact
    19141 gatatgacta ttaacgagtt ctccaatata gatatcattt ttatcaatca catgtaaaat
    19201 aatttcatag ttatcaccta agacatcgtg aagaaatgtg ataaccgttt tccagtagtt
    19261 tagcgtttct ttatccatgt caaacttcct atatctatct tcttatttac aaatatagta
    19321 atacatttta gactaaaaaa caattgccaa tcaccttaat aataattttt tatcaaaaag
    19381 agaatttatt attgactgtg aatgcggttt cctgtaaaat ttaactatat tatcaatgag
    19441 gaggttcgta tatgaagagc tacccagaac caatgggccc ttattcaact tatacgattg
    19501 aaggacattt tctatacacc gcaggccaat taccccttaa tccagtgaca ggtcaattgt
    19561 cagatggttt tgaggcacag tgtcgccagg tttttgttaa tttacaatct attttggcag
    19621 agcaaaagtt ggacttgaat catatctata agctaaatgt gtatttaaca gatgtgacca
    19681 atgtggaaat attaaatcat gtcatgactg atttgtttga agagccttac cctgttcgga
    19741 cagcggttca agtgtcggcg cttcctttgc aagctttgat tgaagtcgaa gctgttgcca
    19801 gagtgaagca gttatagtgt cttatgtaat gagatagatt ggtggaatag attatggata
    19861 ttattattgg aacaagtctt ttgattcttg ttttagctat ttttagcttg tttaactata
    19921 aggctcctca tggtgccaag gcaatgggag ctttagcttc ggcagcttgt gcctcttttt
    19981 tagttgaagc ctttcaagat tctttttttg gtaaggtttt aggctttcag tttctaagtg
    20041 aagtaggcgg agcaaatggc tcattatcag gggtagctgc tgctatcttg gttgccattg
    20101 caattggtgt gtctccaggt tatgccgttt tgattggttt gtcagtttca ggaacaggta
    20161 ttatcccagg ttttgtggct gggtatgtgg tatctttttt aatcaagtgg atggaaaaaa
    20221 atattcctgg tgggcttgat ttaatctcga ttattattgt cggtgcacca ttaactcgtt
    20281 tcttggcgca gttaattacg ccagtgatca atagtacttt attgactatt ggagacatcc
    20341 tgacctcaag tgctaatagc aaccctatta tcatgggaat gatactaggc ggtacgattg
    20401 ttgttgtagc aacagctccg ctatcatcaa tggctttgac agcaatgctt ggtctaacag
    20461 gtattccgat ggctataggt gccttatctg tctttggctc ttcttttatg aatggtgttc
    20521 ttttttaccg attaaaattg ggtgaaagaa aagacaatat tgcttttgct attgaaccgt
    20581 tgactcaggc agatgtgacg tcagccaatc ccattccgat ttatgtgact aattttgttg
    20641 gtggtgctgc atgtggtgtt ttgatcgccc taatgaaatt ggttaatgat acgccaggga
    20701 cagctactcc gattgccggt tttgcggtaa tgtttgccta taatcctgtc gctaaagtgc
    20761 tgataacagc ccttggatgt attattatca gcttaattgt gggttatatt ggaggttctg
    20821 tctttaaaaa ttaccgttta gtaacaaaac aagaattaca agcgagaaac taataaacat
    20881 ctttttgaca ggacttttaa cacgatagca gttatactgt tatcacattg gcttggctat
    20941 tggctggtaa aggttcctta ccgtcaacta gatcaaggtt actaaatgcc taaagaagta
    21001 taagataaca cacgaaagac agcaatacaa agctttagag ttctgtgtca tcttactgct
    21061 ttgacaggtt tttagctaac ctttttctga actaagccat tgtttttatg gatagaattg
    21121 aaagcgctta acttacagat gctgttcgtt taatcaagca attatcctat ctcaaaaaag
    21181 ctgttagtag ataggttaga gatttagctc tagcttatag tcgctggttg attaaccccc
    21241 aaaagtagcc tttcttgtag ctttgttttt aagtacctag tgagtcaaag aattagcaat
    21301 agataaagat aaggagttga tatgtgatga ataccctatt gtcactaatg aatagtatcg
    21361 aacaagaggc tagaacaatt tatgacagtt acgatgctaa gaaaaaatct ctagctgata
    21421 aaaaagaaga agagttaaag cagctgttcc ttgagtacga acaagaaact cagctactat
    21481 tagaagctaa acgtgaggtg ttttttgaag ctaatcgtca agaacaaaaa gcttcaaaaa
    21541 agaggttagc gacgcaacag ctagcccttc atgccatttt agaagagcat aagctaaccg
    21601 ttgttaggga gttagtggat aaggtggtgg agacatatgg ccattagtca aatgaaaaag
    21661 ctggcaatgg tttttgaaaa agattatctt gatcttgttt taaaaacact tcaacaatct
    21721 caattagttg aagttcgtga catgaagcaa ctaaaacatt ggcaagatgc ttttaacaaa
    21781 ggcaacgtca agttgccaca aatcgtccaa tacgatctga cgcatcaaaa acctctacta
    21841 gatgatgaag ctttacaata ccttttacaa agccaacaag agttagaaaa cggccttgct
    21901 agcttatcag cgtttttacc accaatagga aagttaacag ccttgagaca aaaaacgcca
    21961 tctctttcgt ttaaacagtt cgaagaaagc catcgacaac aagcagctca aacggctttg
    22021 aaaatgatgt cacaaaagat agagcgacta gagcagctgc aaaacaaaat agaccagcta
    22081 acagaatact gtcaggagtt agaaaagtgg cgttccttga ctgttttgcc tcaggactta
    22141 gcgcaatttc attttttgtc ggcaagagtt ggaacgattc ctagtacagc aaatgatcat
    22201 ttttatcatc agctaaagca gcacaaaggt ctttttattg aggaagtata ccatacagaa
    22261 tttgagtacg gccttgtctt attttggcaa gcacaagata cgattcattt acagaaatat
    22321 cagtttaaac ccttattata taaagaacag ctactgccat cagaacaact tcgtataaac
    22381 aaagagttac taacgaattg gctagctgaa aaagatagtc tactaaaaga gcttaggcag
    22441 tctcaaaaga tactggcaca gttacaggtt gaaatagact atgtccttag tcagtatcaa
    22501 cggcagcaaa ctaaaaagca attactcggt acaagacatc tgatagcctt agaagggtgg
    22561 atagaagctg attcggttaa ccaattaaaa gggctaatga ctaagacact aggtgatatg
    22621 ttttatctgg atagttacga tgtcacgcca gacgattggg aagatgttcc cattaagcta
    22681 cgtaatcacc gctacattgc accgtttgaa ttggttacag aaatgtacgc tttgccaaaa
    22741 tatcaagaaa aagatccgac acctttttta gcacctttat accttacttt ttttggcatg
    22801 atggtagctg atttgggcta tggtttgttg ctatatgctg tgacactagc tgcattggtc
    22861 ttttttaatc tccaaaaaac cagtaaacgg ttagtgacct tctttaatat tttagctatt
    22921 tcagtagcca tatgggggct tatttacggt tctttctttg gttttgactt acctgtggca
    22981 ttattatcaa ctaaaacgga tgtgattact attttggttg tttctttgct atttgggttt
    23041 gttacactta tatttgggct tttgttagga gcatggcaac aagtaaggat gaaagcatat
    23101 gctacggcct atacgtcaag tctagcttgg acttttattt tattaggcct gctgttattt
    23161 attcttggta agaatgtatc tggccttgct tacttatcgg ttattggtaa gtggcttgca
    23221 ttgggcaatg cctttgggat tttggttgtt tctttactaa aaagcaaaag ccttttaggt
    23281 ctaggtagtg gattatataa tttatatggc attagctctt acttaagtga tttggttagc
    23341 tttactcgtc taatggcatt agggctttct ggagctagta ttggagcggc ttttaacatg
    23401 attgttggga tttttccacc agtcacgcgc tttacagtag gtatctttat ttttattctt
    23461 ttgcatgcga tcaatatttt cttatcaatg ctttcaggat atgtgcatgg tgctcgtctt
    23521 attttcgtag agttttttgg aaaattttat gaaggtggag gaaaagcttt caatccttta
    23581 aagttagctg ataattatgt caatgtcaat gaagaaacag atttggagga caattaacat
    23641 ggaacattta gcacattatt ttacagcaca tggtggcgtt ttcttcgcag ccttaggaat
    23701 tgttttagcc gtagctctta gtggcatggg ctcagcttat ggtgtcggta aaggtggtca
    23761 agcggcagct gcgctcttaa aagaagaacc cgaaaaattc acgtctgcgc ttatcttgca
    23821 actgttaccc ggtagtcaag gaatctacgg ctttgctatt ggtattttaa tttggatgaa
    23881 actgacacca gaactttcag ttaaccaagg attagcttac tttttgatat ctcttccaat
    23941 tgctattgtt ggttattttt cggccaagca ccaaggcaat gtttctgtag ctggtatgca
    24001 aatcttggct aagcgcccta aagactttat gaagggtgtc attttagcag ctatggttga
    24061 aacctatgct attcttgcct ttgtcgtctc ctttattctc ttaaataaaa ttggataagg
    24121 taacggtcct tatctagatt ttaaaaaacg gtgacaccac taacactatc aaaaggggga
    24181 aattaggtga atgatataac acagttaaga caaaacgttc ttgaaaaagc acatcaagaa
    24241 ggtcaacagt gcctaaagat agcgacagat agtctcgata ctgactttaa agagcgtcaa
    24301 cagcaaggac tacacgattt aaaagcaaag cgtcaaaaag agttaaaagc tcttgaacag
    24361 caatttcagg ttgcgcagca gcaactcaaa aaccaagaaa gacaagctct actagcatta
    24421 aaacaagaca gtataaaggg gctatttgaa gcttctttgg agaagatgac gaacttttct
    24481 aaggaagaag aattggcttt tttgaagcaa gtcttgtcta aatatccaga acagccattg
    24541 caagttactt ttggcgaaaa aacagggcaa aagttcagtt cttatgattg tgctgagctg
    24601 agattagcgt ttcctcaatt aagctataat caagagctaa ttcctcagga agcaggattt
    24661 ttagtcagtt tagaccaagt cgatgacaat tatttatacc gttacctttt agaatcagtt
    24721 cttaaagaag aaagctcccg catcattgat atgctttttt cagagatata ggaggtttga
    24781 ctagcgatgc caacatttct agaattaaac actactatca gtgtcaaaga aaaagagtta
    24841 ttgactaaag agcaatttga taagctattg caggctccca atacaacaac cttagctcga
    24901 ctgttgcacc agtcagtcta tcacctaact gttgacgatc tcaacgattt ggatcggcta
    24961 gaatctatct taatggctga gctaaccaag acctatcgct gggcttttgc agaaacccct
    25021 caacctgaca tagtacaatt atttaccttg cgttacacct atcataatgt caaagtgttg
    25081 ttaaaagcta aagctagtca agcagatctg agtcacttat tactaccaat tggtgacaag
    25141 cctttggtgg ctttagaaca tttgattagg acgatgactt ctgatgagtt tccaaaagag
    25201 gtggtaacag aaatccagtc catttgggcc gaatatcaag attatcaaga catacgcgtc
    25261 ttagaaattg gtactgactt agcttatttt aaggcgttga aacaaatagc acaaagatta
    25321 gaggaccctg ttttccaaca agctgttctt attgtgattg atttgtataa tctgattacc
    25381 gtcagacggg ccaaatcgca aaataaacca ataagtttca tgatgcagtt attatctgat
    25441 gaagcaagta gaccaagtaa aacatttatc acacttgaag atgataagga tctgatgacg
    25501 tggtttgaaa atgtaacacc tgatagctat atgacagccc taaaacctta ttcagagaaa
    25561 cttcgccaag gcactcttca aacgactgag ttagaatacc ttgttgatga atgcctttac
    25621 catttatttg cgaaggccaa atatcaagtc gatggacctt atgtgcttgc tcgttttttg
    25681 ctagctaaat cgtttgaagt aaaaaaccta cggcttttag tggctgcttt agctaatgat
    25741 ttacccaaag aacgtgtcat agaaaggatg agaccaatag catgaccaaa acattgtata
    25801 aagtcggggt aattggtaac agagatgtta ttctaccttt tcagatgatt gggtttcaaa
    25861 cttttccagt aataaaacca caagacgcta ttaaccagtt gcgtcaacta gcaatggaag
    25921 actttggtat tatttatatc acagaagata ttgctgcagc tattccagaa gccctcactc
    25981 actatgacaa tcaagttcta ccagcagtca taccattacc aactcatcaa ggagcgcaag
    26041 ggataggcct gtcacgcata caagccatgg ttgaaaaggc tgtcggtcaa aatattttat
    26101 aacactaaga cgttaggcaa agaggactta tactctgttt gaggcttatg agtagctcac
    26161 tgatgaaatg caaggaaagg aaaattggtg aagttagcag ctgaacgcat aggatagttt
    26221 gctgactatt caaaatagtc acattaaacc ttgacagtat agattagtta gtatgatttg
    26281 gaaaaaataa aggaggaaaa aggtgaacca aggaaaaata ataaccgttt cgggacctct
    26341 tgttgtggct tctgggatgc aagaagctaa tattcaagat atttgtcgtg tgggacatct
    26401 tggcttagtc ggagaaatta ttgaaatgcg ccgcgatcaa gcgtctattc aggtttatga
    26461 ggaaacatca gggatcggtc caggagaacc agtagtgact actggttgtc ctttgtcggt
    26521 cgagttaggc ccaggcctga tttcagaaat gtttgacggt attcagcgac cgcttgatcg
    26581 ttttcaaaaa gcaacggaca gcgacttttt aatccgtggt gtggctatcc caagtcttga
    26641 tcgaaaggct aagtgggcat ttattcccaa gctaagtgtt ggtcaagaag tagttgcagg
    26701 tgatatttta ggaactgtgc aagaaacagc tgtcattgag catcgtatca tggttcctta
    26761 taaagtttca gggaccttgg tggctattca tgcagggaac ttcacagtaa cagatacagt
    26821 ttatgaaatt aagcaggaag acggttccat ttaccaaggt agcctcatgc agacttggcc
    26881 agttcgtcaa agtcgccctg ttgctcaaaa gcttatccca gtcgagcctt tggttacagg
    26941 tcaacgggtt attgacacct ttttccctgt tacaaaaggt ggtgccgctg ccgttcctgg
    27001 accatttggg gcaggaaaaa cagttgtgca gcatcaaata gctaaatttg ccaacgttga
    27061 tattgttatt tatgtcggtt gtggggaacg cggcaacgag atgaccgacg ttttgaatga
    27121 gtttccagag ttaattgacc caaatacagg ccagtccatt atggagcgca cggtgttaat
    27181 tgcaaacacc tctaatatgc cagtagcagc gcgtgaagcg tcgatttaca caggcattac
    27241 cattgccgaa tatttccgtg atatgggcta ttctgtggct atcatggcag actcgacatc
    27301 acgttgggca gaagctctgc gcgagatgtc agggcgccta caagaaatgc ctggtgatga
    27361 aggctatccg gcttacttag ggagtcgtat tgccgaatat tatgaacggg ctggtcgtgt
    27421 tcggaccttg ggaagtcaag aacgtgaggg aaccattaca gccatcggcg cggtttctcc
    27481 tcctggagga gatatttcag agcctgtcac tcaaaacacc cttcggattg tcaaagtttt
    27541 ctgggggctc gacgcgcctc ttgcgcaacg gcgtcacttc ccagcgatta actggctgac
    27601 gtcttattca ttgtatcaag atgatgtagg aagctatatt gaccgtaaac aggaatctaa
    27661 ttggtccaac aaggtaactc gtgccatggc tattttgcag cgtgaagcca gtctagaaga
    27721 aattgtacgc ttggtggggc ttgattcact gtctgaacaa gatcgtttga ccatggctgt
    27781 tgcccggcaa attcgggagg attatctcca gcaaaatgcc tttgattcgg tggatacctt
    27841 tacttccttt ccgaaacaag aggccatgct aaccaatatt ttgaccttta atgaggaagc
    27901 cagcaaagcc ctttctttgg gagcttattt taaggagatt atggaaggca ctgctcaggt
    27961 acgcgatcgc atcgcacgca gcaaatttat cccagaagaa aacttagagc agattaaagg
    28021 gcttactcag aaggttacca aagagattca ccacgtttta gcaaagggag gaatttagat
    28081 gagcgttctc aaagaatatc ggacggttag cgaagtggtt ggccctttga tgattgttga
    28141 tcaagttgca ggagtgcact acaacgaatt ggtagatatt actttgcata atggagaaag
    28201 gcgtaaaggt caagtcttag aagtccaagg tgacaaggct atggtacagc tatttgaagg
    28261 atcaactggc atcaacctag ccaaaaccaa ggttcgattt acagggcatc ctttggaatt
    28321 agccgtatca gaagatatgg tagggcgcat ctttgatgga atggggcagc ccatagacgg
    28381 cggtccagaa cttattcccg aaaaatacct tgatatcgat ggtcaagcga tcaatcctgt
    28441 cgctcgtgat tacccagacg aatttatcca gacaggtatc tcagctattg atcacctcaa
    28501 taccctcgtt cgtggtcaaa agttaccagt tttttcgggc tcagggttac ctcataatga
    28561 attggccgca cagattgctc gtcaggcaac tgttctaaac tctgatgata actttgcggt
    28621 tgtgtttgca gctatgggta ttacttttga agaggcagaa ttctttatga atgacttgcg
    28681 tgaaacgggt gccattgatc gatctgtttt atttatcaat ttggctaatg accctgctat
    28741 tgaacgcatt gcaacaccac gtatagctct gacaacagcc gaatacttgg cttatgaaaa
    28801 aggtatgcat gttttagtca tcatgacaga tatgacaaat tattgtgaag ccttacgaga
    28861 agtatcagcc gctcgcagag aagttccagg cagacgaggt tatcctggct atctctatac
    28921 taatctctcc accttatatg aacgggctgg tcgtctgatc gggaaaaaag ggtcagtgac
    28981 tcaaattcct attttaacca tgccagaaga tgacattacc caccctatcc ccgatttgac
    29041 aggttatatt accgaaggtc agattatttt gtcgcaagaa ctatataaaa atggttttag
    29101 accgcctatt aatgtcttgc catcgctatc tcgcctaaaa gataaaggct caggtgaagg
    29161 taagactcga caagaccatg ctgccacaat gaatcagctc tttgcagcct atgcccaagg
    29221 aaaacaagct aaggaattgg ctgttgtgct cggtgaatca gccctttctg aaacggataa
    29281 actatatgtg gcctttacca accggtttga agaagaatac attaaccaag gattttacac
    29341 caaccgtagc attgaagaaa gtcttgactt gggttgggaa ttgttgtcga ttttgccacg
    29401 taccgaatta aaacgcatta aagatgatat gttagatcgt tatttgccta aagcagatac
    29461 cacgatgaca aaggtttttg ttgcaaatga ttgagttgac catgcaattt caagcccttg
    29521 acgaaaggag ttatatcaat ggcacgatta aatgttaaac caacacgcat ggaacttagt
    29581 aacttgaaaa atcgcttgaa gacagctaca agaggtcata aattattaaa ggacaagcgg
    29641 gatgagttga tgcgtcgctt cgctgattta attcgtgaaa acaatgagct tcgtcaaact
    29701 atcgaaaaag aacttgctgc caatatgaag gagtttgtct tggcaaaagc atccgaaaat
    29761 agtctaatgg tagaagaact ctttgctgtt ccagtccatg aagtgacctt atggattgat
    29821 attgaaaata tcatgagtgt caatgtgcct aaattccatg tccagtctaa tacggcaaga
    29881 gagcaagaac aaggtgagtt tgcttatagt tacctcagct caaatagtga gatggacaat
    29941 actatccaaa agacaaaaga actattagaa aagctcttac ggttagctga agttgaaaaa
    30001 acttgtcaac taatggctga tgacattgaa aagactagac gtcgcgtcaa tggcttagag
    30061 tattctatta tcccgcaact ggaagagacg attcactaca ttgagttgaa attagaagag
    30121 gccgagcgtg ctagccttgt tcgtattatg aaaataacat cataaaagat aagtgttata
    30181 tcaaacaagg cgattattcg ttaagtagta aaaaagcaag acatcaaagg gattaaccta
    30241 attgatggct tgctttttaa gtagcgtgac aggtgatgtt tagcttatgc gtgagttgtt
    30301 ttatcaattg ttttttgagt ttccttgcct tcactaagaa gtgcttgcac aatattttgg
    30361 tcacgtagtt tgacagaatc gttaatggtt tcggcagacc tgataatagc actttctagt
    30421 tgtgctcgtt ctttgcgtcc atgatcaatc gccgcaatga tcccattatt ttgtgctact
    30481 aaactttctg ccagacttgt cacagatttc atagacaaag tagggttttg tgctgattgt
    30541 tccaatgctg ggatggcttc tttgctggtt tccgccaaca tctgaagggc agcattatta
    30601 gcattaataa tggcgtcagc agtcattcca gatttaaccg attgttgcat catgcctaac
    30661 tgagcaatag atagtttcat cgttggaatg gtattgcggc gtaacatgcc tagtttttga
    30721 cgcatgtcag aagagacctt gactagatta cgcatttgcg gagtcgtcgc ccaagcaaca
    30781 tagaggcgac tcaagtattc ggtgtgttgt tgttcgaggg tgttgatgac ttcggtagtt
    30841 cttgccaaaa gatcagcttt tatttgatag tctggtgtag cactgtcttt ggtttttagg
    30901 tctttttgta aagccgcagc gcgctgacta gcttcttttt gactagcttc gataaaagca
    30961 atgacgccta ccaaatgttc aatggactta gtattatctt caattaacaa ttctgctgag
    31021 acaatattgc gagctaaggt atcttcttgc ttgacaaccg ctgcagccat actatccatt
    31081 ttttgctcaa tgttttgaga atcaaaataa aactcttgca gggtatcacg gctttgttta
    31141 aagagttttt gaagaaagtt tggcttttta tcaaggtcca caggtgtggc atccttgtat
    31201 ttagcgataa aaccattgag ttcacgattg gttgatttta aaagatcatc aacctgagga
    31261 atctgtaatt ttttttgctc tgccaagata tgattaaccg ttgcattgac cccttcaaca
    31321 gcagactgac caaaatcaag tagcgcattt tggtctgcca aaaaggtatc taccaatgcc
    31381 ggggctttgg cagtaatagc tgtctgctgg tcagcactta gtttctcaaa aaaagagatt
    31441 tggccatttg tgtcagttgg taagtctgag ataatatcgg tggttttatc ggttttgaca
    31501 acagcattgt cagcaatttg gtcaatgtca aaattaaaat ctgccataaa gggactcctt
    31561 tagtcttttt ggtgatgcgt tgttcgtctt tgagtagcac cttgcatgat tcgaaggcta
    31621 atatcaaaat ctttaagatc actttcattg agtcgacgaa gggtttcgtc aagatcttca
    31681 tcaaattgtt ggatagcttg tttggcttgt tctaaacgag cagcagcgtt atagtaattt
    31741 ttaggctctt ctttgatttt taagtagcct gttaagatat cctcaaacct tctcatgtta
    31801 gcttcatgca gcgcaagcaa ttcttcttga ttgtcggctc cttggatttt agcaaggata
    31861 gcttgatgat ctgtctgaat attatcataa tacggtttga gctcaggtgc tttgttaata
    31921 agattaggag atggggtttt caaaggctga gggttaagag ttgtggcaat ctgcagtgtt
    31981 tcgagttgaa gggtaatatc actttcaacg tcattggctt ttttggtgat acgacgataa
    32041 attttgggat ctaactggtc ttttaacgta atagcttttg ctttgatgtc actaagttgt
    32101 ggtaataatt gctgagcaag tacgttatat tggaagtcat catggtctgc cagataagtg
    32161 tctaacagcc gaactttacg atcagctagc tgaatttttg cttttagatc ttctaattgt
    32221 ttggcaatct tggcctttgc tagccgcttt tgatgagatc taacacgaaa aatagcataa
    32281 cctgtaccac caatggctat ggcaggcaaa atgtctagaa gtgactcagt aaaagaagag
    32341 ccacctataa agcttgaaat cataaaaaaa gcaatgatta gccaaatcca gtttagtgat
    32401 ttcttttttg tgctcgtgcg gtcatacttt ctaatcatgt gatatttcct cgatatgttt
    32461 ttactggcta tctcatagag gtaacttact attattttac cttaaaaccg ctatttctga
    32521 aagaaaagag ctaatgtttt aagagaatcg tttaaccctg ctaaagctta ggagaaacga
    32581 ggttaaaagc ttttctctta taatgttcgt ttttttagga ttgtttatca tggttaaaaa
    32641 aagagtttct ctttttcctt aataatgcta agaaatctag cagaaaaaat cattttttgc
    32701 tataataagt tgtaaggtat atgctagcag gtgagattcc tgcctgtttt ctttaaatat
    32761 caagagctac attgctgatc ttacagatct gaccttcttt ttggttttta agcagtggtt
    32821 agcttgccta tgatttttat tgagaataag tgtttcagaa agttaggaca atgatatgac
    32881 atctgtagtt gttgttggta cccagtgggg tgacgaaggt aaaggtaaaa tcactgattt
    32941 cttgtcagcg gatgcagaag taattgctcg ctatcaaggt ggtgataatg ctggtcatac
    33001 gatcgtgatt gatggtaaga agtttaaact tcacttgatc ccatcaggaa ttttcttccc
    33061 gcaaaaaatt tccgttattg gtaatggcgt tgtggtcaac cccaaatctt tggtcaaaga
    33121 gttggcgtac ctgcatgatg aaggagtgac gacagataac cttcgcattt cagaccgagc
    33181 tcatgttatt ttaccttatc atatccagct ggatcaactg caagaagatg caaaaggtga
    33241 caataaaatc ggaacaacta ttaaagggat tggtccagct tatatggata aagctgctcg
    33301 agttggtatc cgtatcgcag atttactgga taaggatatc tttgcagagc gcctacgcat
    33361 taatttagct gagaaaaacc gtttatttga aaaaatgtat gacagtacac ctcttggttt
    33421 tgatgctatc tttgaggagt actatgctta cggtcaagaa atcaagcaat atgtgacaga
    33481 tacttctgtg attttaaatg atgcacttga tgctggtaaa cgtgttcttt ttgaaggtgc
    33541 tcaaggggtt atgcttgata ttgaccaagg aacttaccca tttgtaacgt cttcaaaccc
    33601 agttgctggt ggtgtaacca ttggttctgg tgttggccca agtaaaatca acaaagtagt
    33661 tggtgtctgt aaagcctaca caagccgtgt cggtgatggg ccattcccta cagaactctt
    33721 tgatgaagtg ggtgagcgca ttcgtgaagt gggtcatgag tacgggacaa cgaccggccg
    33781 tccacgtcgt gtcggttggt ttgactcagt tgttatgcgc catagtcgtc gtgtgtcagg
    33841 gattactaac ctctctctga attcaattga tgttctttca gggcttgata cggttaagat
    33901 ttgtgtggct tatgaccttg atgggaaacg tattgactat tacccagcaa gccttgaaca
    33961 actcaaacgt tgcaaaccaa tctatgaaga attaccaggc tggcaagagg acatcacagg
    34021 tgttcgtagc cttgatgagc ttcctgaaaa tgcccgcaac tacgttcgtc gtgttggaga
    34081 attggttggc gttcgcattt caaccttctc agttggtcca gggcgtgaac agaccaatat
    34141 tcttgagtca gtctgggcat ctatctaagg tgtctagtat gacaaagagt tggatagcgt
    34201 ttccagctct ttttaccgct tgttggattg tatagttagt catgctatta ctagtagctt
    34261 gagttttgtc gttgtcttat ctccttaaga ggtgattttt gaggagataa cgggttttac
    34321 cagttgatct cactttctcg ttcggtcatt ttggtgaaaa agagattttt cagcaaaaat
    34381 agtaggataa aactgatttt tttgatatac taaacttttc gttctagagc ataagtagaa
    34441 cgttaacaat gacacatcac tttaggatta aacatttagg aggttcattt tcacatgaac
    34501 aaaaaagtaa tgtcacttgg tcttgtttcg actgccctat tcacattagg aggctgcacc
    34561 aataactcct ctaaacaaac aactgacaat tcattaaaaa tcgctatgat cactaatcag
    34621 acgggtattg atgacaagtc atttaaccag tcagcctggg aaggcttaca agcttgggga
    34681 aaagaaaata aacttgaaaa aggaaaaggc tatgattatt tccaatcagc caatgaatca
    34741 gagtttacca caaaccttga gtcagcagta accaatggtt ataatcttgt ttttgggatt
    34801 ggatttccat tacatgacgc tgtagaaaaa gtagccgcaa acaatcctga caaccatttt
    34861 gcaattgtgg atgatgtgat taaaggtcaa aaaaatgttg caagtatcac cttttcagac
    34921 catgaagcgg catacctagc cggtgttgca gcagctaaaa cgacaaaaac caagcaagtt
    34981 ggttttgtag gtggtatgga aggagatgtt gtcaagcgct ttgaaaaagg ttttgaagct
    35041 ggtgtgaaat cagtagatga taccatcaaa gtaagagttg cttatgcagg ctcttttgca
    35101 gatgctgcca aaggcaagac gattgcagct gctcaatatg ctgaaggcgc agatgttatt
    35161 tatcatgcag caggaggcac aggggcgggt gtctttagcg aagctaagtc tatcaacgaa
    35221 aaacgtaaag aagaagataa ggtttgggtt attggtgttg accgtgacca aagtgaagat
    35281 ggaaaataca ccacaaaaga tggcaagtca gctaattttg ttttgacctc aagtatcaag
    35341 gaagtcggaa aagctttagt aaaagtagcc gtaaaaacct cagaaggcca attcccaggt
    35401 ggtcaaataa ccacttttgg tttaaaagaa ggtggtgtta gccttacaac ggatgctctg
    35461 acacaagaca ctaaaaaagc tattgagact gctaaaaaag cgattatcga aggaaccatc
    35521 acagttcctg aaaactaaaa ctgtacaata ccgtccagag tcgtcacgaa ccgactttgg
    35581 actttttaat aaaggtgtca agtagctcca cagatacgtt gacaccagcc ctgtctttta
    35641 ttataatgaa ggtgatagaa aacagcgcaa aagccaaaaa aagggctttt ttataatgaa
    35701 aggaaacatc atgctagatt catttgataa gggctggttc gtcctccaaa cttactcagg
    35761 ctacgaaaac aaagtaaaag aaaacctctt gcaacgtgcc caaacctata acatgttgga
    35821 caatattttg cgcgtcgaaa ttccgacaca aacggttaac gttgaaaaaa atgggcaaac
    35881 caaagaaatc gaagaaaatc gctttccagg gtatgtcttg gttgaaatgg tcatgacaga
    35941 tgaagcttgg tttgttgtgc gtaacacacc aaacgttaca ggttttgtgg gatcacacgg
    36001 gaaccgatca aaaccaacac cacttcttga agaagaaatc cgtgctatct tgttgtctat
    36061 gggtcaaacc attgatgtct ttgataccaa tatcaaagaa ggtgatgtgg ttcagatcat
    36121 agacggtgcc tttatgggac aagaaggtcg tgtggtagaa atcgaaaaca acaaagtgaa
    36181 gctgatgctc aacatgtttg gctctgaaac agtagcagaa gttgaacttt atcaaattgc
    36241 agaactatag gctctcaaag gtctgatggt ataagtatta ccatcagacc ttttttagtt
    36301 ggcagtgaag cgtgtttaca aaccaatgga tgactattgt taacatcatt gtaatcagaa
    36361 ataattaaca gatctattac tgataacggt gctactatca aatatttaac tagtactttt
    36421 aatctggttt aaatagaaca gatgtgaagg ttctgtgata ataagatgga aatatcccct
    36481 tgaaacttgt aacagttggc tacttgtttt tttgtgttca tttttttgat agaaaagcct
    36541 aaaacgatgt taataaatcg cattgacaaa aactagttgt taatgtatag tttacttaaa
    36601 aataatataa ggtggtttac atgagaaaca aaaaagtaac attagctcat attgtcgcaa
    36661 agacaagtgt tgctattgct ttggctggag caatgggtag cagtttatta gctaatagca
    36721 caacgtacgc tgttagtggc aaagaaaata aaaaaagcga tgtcaaatat gaaacgacca
    36781 aagttatgga agctaacgca acttcctcta aagaagacaa tcatgtcatg cacacattag
    36841 acggctcaat gagtactgtc tgggaggaaa attcacctgg tggtggcgtt ggtgaggtac
    36901 tttcctacaa gtttgtttcc ccgatgcgta ttgggagaat tttaattgtg aatggagata
    36961 catctagcaa ggagaattac tacaagaaaa atagaattgc aaaggctgat gttaaatact
    37021 ataacgggaa taaattggtc ctctttcaaa aaattgaatt aggcgacacc tacactaaaa
    37081 aaccgcatca cattgagatt gataaaaaat tagatgttga tcgtattgat attgaggtaa
    37141 cagaggtcca tcagggacaa aacaaggata ttttagcctt gtcagaggtc acttttggca
    37201 atatggaacg cgatcttttt gaaaaaaagt ttaaagaaat taaagataaa tgggtaacag
    37261 ataaacaagc agatgagttt attgaaactg ccgacaagta tgctgataaa gctgttcaga
    37321 tgtctgctgt tgcgtcacgt gctgagtatt accggatgta cgttagccgc aaataccact
    37381 acaaaaaaga gtttgttgaa aaactaaaac aagtctacaa agaaagcgga gcttctcacg
    37441 ttacaagtaa aaaagatttg atgttagctt ttgatgatgc taaaagaaag tcaacgattg
    37501 gtcgacaaga aaacggtctt tttgtgacaa gttttgctga agatatggca ttgctcttta
    37561 ctgatcaagg taagttaaaa tcagctgacc aaattgaaaa tataaaaggt gtcgatagcg
    37621 gaaaatatag cgatggagtt tatcaatatg agtacgattc tgaactaaca aaaaacattg
    37681 ataagctagg ctatatccga acagctagcg gagatacccc tggagcaaat tcgctcaaca
    37741 ttcctggttg ccaaacgtgg tcaggaaaac acattgaaaa ttcagaaagt gagttaattt
    37801 tcccatcgat tagtgttaaa gatctaaaat ctaaagctgt cttagcagag attgatgcca
    37861 aaggctattt tgaaattatt gatcctacca tcattgctcc aaatggtgac cataaaaaag
    37921 taactggtcg cttcaaaatt aagaaaatgc aagatagaat gcaagatagg aagtaacaat
    37981 atgtataagg tgccaaagag tttagaacat taccaaaaaa tgtttcaaaa agaagtaact
    38041 gttaatgatt taaaaaaata cttgataggt agtgacaaag agtatcgtat cactagaaga
    38101 gactcctata tgggagatat ttctgatcca gaagttattt tagagtatgg ggtttaccct
    38161 gctttcataa aaggctatac ccaattgaaa gctaacatcg aagaagcatt attagaaatg
    38221 tcaaatagcg gtcaagcatt agacatttac caagcggttc aaaccctaaa cgctgaaaac
    38281 atgttattaa attattacga aagcttgcca ttttatttaa accgtcaaag catactagct
    38341 aatataacca aagcgttaaa agatgcgcat attagagagg ctatggtaca ttacaaatta
    38401 ggagaatttg ctcactatca agatactatg cttgatatgg tcgaaagaac aatagaaaca
    38461 ttttagaatg ataaaaaggt atgaaggaca tgtctaacaa aaaaacattt aaaaaataca
    38521 gtcgcgtcgc tgggctacta acggcagctc ttatcattgg taatcttgtt actgctaatg
    38581 ctgaatcgaa caaacaaaac actgctagta cagaaaccac aacgacaaat gagcaaccaa
    38641 agccagaaag tagtgagcta actaccgaaa aagcaggtca gaaaatggat gatatgctta
    38701 actctaacga tatgattaag cttgctccca aagaaatgcc actagaatct gcagaaaaag
    38761 aagaaaaaaa gtcagaagac aaaaaaaaga gcgaagaaga tcacactgaa gaaatcaatg
    38821 acaagattta ttcactaaat tataatgagc ttgaagtact tgctaaaaat ggtgaaacca
    38881 ttgaaaattt tgttcctaaa gaaggcgtta agaaagctga taaatttatt gtcattgaaa
    38941 gaaagaaaaa aaatatcaac actacaccag tcgatatttc catcattgac tctgtcactg
    39001 ataggaccta tccagcagcc cttcagctgg ctaataaagg ttttaccgaa aacaaaccag
    39061 acgcggtagt caccaagcga aacccacaaa aaatccatat tgatttacca ggtatgggag
    39121 acaaagcaac ggttgaggtc aatgacccta cctatgccaa tgtttcaaca gctattgata
    39181 atcttgttaa ccaatggcat gataattatt ctggtggtaa tacgcttcct gccagaacac
    39241 aatatactga atcaatggta tattctaaat cacagattga agcagctcta aatgttaata
    39301 gtaaaatctt agatggtact ttaggcattg atttcaagtc gatttcaaaa ggtgaaaaga
    39361 aggtgatgat tgcagcatac aagcaaattt tttacaccgt atcagcaaac cttcctaata
    39421 atcctgcgga tgtgtttgat aaatcagtga cctttaaaga gttgcaacga aaaggtgtca
    39481 gcaatgaagc cccgccactc tttgtgagta acgtagctta tggtcgaact gtttttgtca
    39541 aactagaaac aagttctaaa agtaatgatg ttgaagcggc ctttagtgca gctctaaaag
    39601 gaacagatgt taaaactaat ggaaaatact ctgatatttt agaaaatagt tcatttacag
    39661 ctgtcgtttt aggaggagat gctgcagagc acaataaggt agtcacaaaa gactttgatg
    39721 ttattagaaa cgttatcaaa gataatgcta ccttcagtag aaaaaaccca gcttatccta
    39781 tttcatacac cagtgttttc cttaaaaata ataaaattgc gggtgtcaat aacagaagtg
    39841 aatacgttga aacaacatct accgagtaca cgagtggaaa aattaacctg tctcatcaag
    39901 gtgcctatgt tgctcaatat gaaatccttt gggatgaaat caattatgat gacaaaggaa
    39961 aagaagtgat tacaaaacga cgttgggaca acaactggta tagtaagaca tcaccattta
    40021 gcacagttat cccactagga gctaattcac gaaatatccg tatcatggct agagagtgca
    40081 ccggcttagc ttgggaatgg tggcgaaaag tgatcgacga aagagatgtg aaactgtcta
    40141 aagaaatcaa tgtcaacatc tcaggatcaa ccttgagccc atatggttcg attacttata
    40201 agtaggactg gttcaagagg ttcgtcaagc accttgatgc tgcttatctc ttgaggcctt
    40261 gtgcctaatc ctctcacaaa tacagaagaa agcttgtcta tgagatacct tcatagacaa
    40321 gcttttttga tatactaatc aaaaaattat tcttttctca catcgtgacc ttgaagctaa
    40381 gctgcttcta atctataata ctaacaagct gctttttaac aagcaaagca taacataaaa
    40441 gggagagata actattatca tgaaacaaca atcttaccag cctctacgct tcgtctacct
    40501 cttggtggct ctatttgctg ctatgttgct tatagcaaga cctgttatgg cagatgggga
    40561 gaataatgac ccagctaatg cagcatatta taaagggaaa agcgctggaa aagaagctag
    40621 ttggactgat ttgaccccaa ctaatccaac cattccagaa ccacctagtg atatcagaga
    40681 gactactaat aaacagcatt ataaagacgg gtatacagat gggtacagag atggttataa
    40741 tgaaggctgg aaatctcagc atcccgtctt gactccggtc aaggttatat gggatttgat
    40801 ctctcattgg ctacagcaat tcttccccaa taaccaggca actacaacag tacaaagcat
    40861 gtcataataa aaatgaatta aaaacagcct ttaactgcta atgtgaaagg ttgttttttt
    40921 aggatatggg aatgaacaat aaaaaaagag tttgtgaaaa agcctctcgg ccacacaaaa
    40981 aaacaatggc gtcaaagcca ttgttttttt agcataatca agagactact gtctcagact
    41041 ctcaagtaat ttttactcag agtagtaata tccccaagtg caataatatg ctgctgactt
    41101 gccccaacct cttaacaaat cgcgcataca ggtcaatgga caacaagacc attttggacc
    41161 acaatctgga catcctacac aagtaacttg cgtgtcattt gctgaaacag tttggttttc
    41221 tggtgttgca aggctaaggc ttacgacagc agcagttgcg atcataaata aagataattt
    41281 ctttttcatt tgtaactcct taaattatag tatacctata ttatactcat attatgttaa
    41341 tgattcaata tcacatttta atctttttgt tatgtgtttg accgaaaaag gcaaagaaat
    41401 ccgatactaa agcatttctt tatcttatat aaataacatt aattattaat aatgttaatc
    41461 tggttataat tatatttgag gtgttacagc ttttttggtg gtggttagct agcaactgtt
    41521 acgacttgtg ttttgggctt gtccttttat aggcggtatg ccttttcttt ttaatcttga
    41581 gggatcgtta gtaaaaacgt tttagccaat caaaaagcct agaactgctt acgcagctct
    41641 aggcttttca taaccgtagt cttacgaaga agatagcttc tatgttacgg tattaggttt
    41701 accatactgt gtaaagtaac cagctgtcag gaccagtgtg tccgtagaaa ccgttactat
    41761 agctagcatc atttgctgaa acagtttggt ggcttcctag tgttgcaagg ctaaggcctg
    41821 caacagcagc agttgcgatc ataaataaag ataattt
//
LOCUS       DAUGUF010000015        40802 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUGUF010000015 DAUGUF010000000
VERSION     DAUGUF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40802
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.015"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..117)
                     /locus_tag="VIB71_000793"
     CDS             complement(<1..117)
                     /locus_tag="VIB71_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ8822542.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEY"
     gene            complement(186..257)
                     /gene="shp3"
                     /locus_tag="VIB71_000794"
     CDS             complement(186..257)
                     /gene="shp3"
                     /locus_tag="VIB71_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEQ8822543.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            337..1188
                     /gene="rgg3"
                     /locus_tag="VIB71_000795"
     CDS             337..1188
                     /gene="rgg3"
                     /locus_tag="VIB71_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEQ8822544.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1441..4980)
                     /gene="smc"
                     /locus_tag="VIB71_000796"
     CDS             complement(1441..4980)
                     /gene="smc"
                     /locus_tag="VIB71_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEQ8822545.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVISQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLKQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGTNRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAIIQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(4981..5673)
                     /locus_tag="VIB71_000797"
     CDS             complement(4981..5673)
                     /locus_tag="VIB71_000797"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEQ8822546.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6105..6914)
                     /locus_tag="VIB71_000798"
     CDS             complement(6105..6914)
                     /locus_tag="VIB71_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8822547.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(6918..8270)
                     /gene="vicK"
                     /locus_tag="VIB71_000799"
     CDS             complement(6918..8270)
                     /gene="vicK"
                     /locus_tag="VIB71_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEQ8822548.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8263..8973)
                     /locus_tag="VIB71_000800"
     CDS             complement(8263..8973)
                     /locus_tag="VIB71_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8822549.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9135..10169)
                     /locus_tag="VIB71_000801"
     CDS             complement(9135..10169)
                     /locus_tag="VIB71_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8822550.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PMIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10225..11472)
                     /locus_tag="VIB71_000802"
     CDS             complement(10225..11472)
                     /locus_tag="VIB71_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ8822551.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLEKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKMFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     ALNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(11429..12577)
                     /locus_tag="VIB71_000803"
     CDS             complement(11429..12577)
                     /locus_tag="VIB71_000803"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEQ8822552.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNAVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWILRSHQKASYCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGHYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(12972..13121)
                     /locus_tag="VIB71_000804"
     CDS             complement(12972..13121)
                     /locus_tag="VIB71_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEQ8822553.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(13207..13992)
                     /locus_tag="VIB71_000805"
     CDS             complement(13207..13992)
                     /locus_tag="VIB71_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822554.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFVIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESAGS"
     gene            complement(13994..14812)
                     /locus_tag="VIB71_000806"
     CDS             complement(13994..14812)
                     /locus_tag="VIB71_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEQ8822555.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLVVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(14814..15806)
                     /locus_tag="VIB71_000807"
     CDS             complement(14814..15806)
                     /locus_tag="VIB71_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8822556.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRILSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELRPGQEQVVSQFMGLPDIT
                     VERHELSLDIQYDSSRYQTADIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(15947..17890)
                     /gene="thrS"
                     /locus_tag="VIB71_000808"
     CDS             complement(15947..17890)
                     /gene="thrS"
                     /locus_tag="VIB71_000808"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEQ8822557.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(18312..19646)
                     /locus_tag="VIB71_000809"
     CDS             complement(18312..19646)
                     /locus_tag="VIB71_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8822558.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGNGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAVIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19648..20646)
                     /locus_tag="VIB71_000810"
     CDS             complement(19648..20646)
                     /locus_tag="VIB71_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ8822559.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADSKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20777..21778)
                     /gene="ccpA"
                     /locus_tag="VIB71_000811"
     CDS             complement(20777..21778)
                     /gene="ccpA"
                     /locus_tag="VIB71_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEQ8822560.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            21952..23037
                     /locus_tag="VIB71_000812"
     CDS             21952..23037
                     /locus_tag="VIB71_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ8822561.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFRYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTSYVQGMRLVKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23086..23751
                     /locus_tag="VIB71_000813"
     CDS             23086..23751
                     /locus_tag="VIB71_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ8822562.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23762..24139
                     /locus_tag="VIB71_000814"
     CDS             23762..24139
                     /locus_tag="VIB71_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ8822563.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24284..25210
                     /locus_tag="VIB71_000815"
     CDS             24284..25210
                     /locus_tag="VIB71_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ8822564.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMSNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPVMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25421..26104
                     /locus_tag="VIB71_000816"
     CDS             25421..26104
                     /locus_tag="VIB71_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEQ8822565.1"
                     /translation="MEWIKLIGIVIIVLGFILKCDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQALTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26104..27030
                     /locus_tag="VIB71_000817"
     CDS             26104..27030
                     /locus_tag="VIB71_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEQ8822566.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27080..27727
                     /gene="pcp"
                     /locus_tag="VIB71_000818"
     CDS             27080..27727
                     /gene="pcp"
                     /locus_tag="VIB71_000818"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEQ8822567.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKYIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(27842..28561)
                     /locus_tag="VIB71_000819"
     CDS             complement(27842..28561)
                     /locus_tag="VIB71_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEQ8822568.1"
                     /translation="MSIMITKGQVCLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28567..29034)
                     /gene="smpB"
                     /locus_tag="VIB71_000820"
     CDS             complement(28567..29034)
                     /gene="smpB"
                     /locus_tag="VIB71_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEQ8822569.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLAPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29037..31370)
                     /gene="rnr"
                     /locus_tag="VIB71_000821"
     CDS             complement(29037..31370)
                     /gene="rnr"
                     /locus_tag="VIB71_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEQ8822570.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKVIVNDKGIPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYSQPSQEKRDHFTQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVASVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGIK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31464..31700)
                     /gene="secG"
                     /locus_tag="VIB71_000822"
     CDS             complement(31464..31700)
                     /gene="secG"
                     /locus_tag="VIB71_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEQ8822571.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31746..31892)
                     /gene="rpmG"
                     /locus_tag="VIB71_000823"
     CDS             complement(31746..31892)
                     /gene="rpmG"
                     /locus_tag="VIB71_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8822572.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(31889..33082)
                     /locus_tag="VIB71_000824"
     CDS             complement(31889..33082)
                     /locus_tag="VIB71_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEQ8822573.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVTPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33204..34706)
                     /locus_tag="VIB71_000825"
     CDS             complement(33204..34706)
                     /locus_tag="VIB71_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEQ8822574.1"
                     /translation="MTTMTIAKGSQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISEMGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSDI
                     ESQQLVQSSPFASKYSQSIDRDSAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
                     QAATKKANRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(34896..35489)
                     /locus_tag="VIB71_000826"
     CDS             complement(34896..35489)
                     /locus_tag="VIB71_000826"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEQ8822575.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPNNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR"
     gene            complement(35486..36313)
                     /gene="mutM"
                     /locus_tag="VIB71_000827"
     CDS             complement(35486..36313)
                     /gene="mutM"
                     /locus_tag="VIB71_000827"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEQ8822576.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(36485..37351)
                     /gene="rgg2"
                     /locus_tag="VIB71_000828"
     CDS             complement(36485..37351)
                     /gene="rgg2"
                     /locus_tag="VIB71_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEQ8822577.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37440..37508
                     /gene="shp2"
                     /locus_tag="VIB71_000829"
     CDS             37440..37508
                     /gene="shp2"
                     /locus_tag="VIB71_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEQ8822578.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38422..38691
                     /gene="stcA"
                     /locus_tag="VIB71_000830"
     CDS             38422..38691
                     /gene="stcA"
                     /locus_tag="VIB71_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEQ8822579.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTTMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39039..39437)
                     /locus_tag="VIB71_000831"
     CDS             complement(39039..39437)
                     /locus_tag="VIB71_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEQ8822580.1"
                     /translation="MHRLLNRLIPEEDNNKLSRAAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLAHHLLHSDGVIPSLNDKSA"
     gene            complement(39530..40600)
                     /locus_tag="VIB71_000832"
     CDS             complement(39530..40600)
                     /locus_tag="VIB71_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822581.1"
                     /translation="MMMLRDVKVKTSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGAFPDNIK
                     VSINPKGRQATITYGDGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
BASE COUNT        12296 a         8679 c         7158 g        12669 t
ORIGIN      
        1 atattcaaat aattcatctg atatagaatg ttcaactgga ttaccaagca atgcagaata
       61 cataaatttc atcctcctac gtttaattag tttactacta acataaagta caagcattac
      121 acagagctaa ccattaccta taagtcttta gagtatctaa agacttaggt atacacctaa
      181 gtaacttacc caccaacaat aatgataata tccattgcta aaattaaaat cggcaaaaat
      241 tttgaaattt tcttcataag tggacttcct ttcagttttt atttattgta caataaaaaa
      301 aaacggaatt gatttttgtt gggaaagtgg gaaaatatga aatcaaaact tggtgccaca
      361 cttagaaaag ttcgaaaagg aaagcaaatt agtctgtgct tcgtggcaga tgaacacctt
      421 tcaaaatcac aaatctctcg ttttgagcgc ggggagtcag agatatcgtg tatccgactg
      481 atcaatattc tagacaaatt acacattact ttggatgagt tccttatttt acatgatgaa
      541 gactatacca attccgaaac atttgctaac ctggtacagt atattcgtaa gcaatattca
      601 tcacaaaata tcaataatat agcatgttta ctttccgaca cttctgatta cactctgaat
      661 tcttttgaga aaacaatggt aaagtccatt ttacacacaa tggattcaag catcattcca
      721 tcagatgatg aattacttca actaacagat tatctcttta aagttgaaaa atggggctac
      781 tatgaaatcc ttttattggg taactgtgta cgaacaatta actacaactc ctacttccta
      841 ttgacaaagg agatgttaaa taattacatt tactcttcac ggaacaaaac taataaacga
      901 attgtcactc agcttgctat aaattgtttc attcttagca tcaataagga ggaattttct
      961 aattgctcct atttaattga tgagataaaa accttgttag ataatgaatt aaacttctat
     1021 gaacagacag tttttctcta tgcaacaggt tactttgaat ttaagcgcca attagaaact
     1081 ggagttgaaa agatgaaaca agccatacaa gttcttgata ttttaaatga agacaagtta
     1141 aaattacatt acgctgacca ttttgataaa ctagtcaaca aagattaagt gaaatcattc
     1201 tttacctttt aacgaaatgc caatcaagag tgtctcaata aaaaatcatc tactctgaca
     1261 acttttctct tttacctatc gacagctaaa aagccttgga aactgctatt tccaaggctt
     1321 tctttgtact ctattgtatc aattagctta ttccgatttc tgttgctatt agtttaatca
     1381 tgaaatctcc taacttatgg ccgaacatcc aaaaaaacag aaggaactgc cttctgtttt
     1441 ttaattggtc atctcttgag cttcttttaa ttttacagat acaattttag agacccccga
     1501 ttcctgcatg gtaattccat aaatactatc tgctgcagcc attgttcctt tacgatgggt
     1561 cacgacaata aattgactat ctttgtcaaa gcgattgagg aaatccccaa agcgcttaac
     1621 atttgcttca tcaagagccg cttctacctc atctaaaatc acaaacggaa tcgttttaac
     1681 acgtataata gcaaacaata aagccagtgc tgacaaagct ttttctccgc ctgacatcaa
     1741 gttaagagat tggattttct taccaggagg ctgcacagaa atctctatac cagcagacaa
     1801 gagatctgtt tccgttaaaa ccaaatcagc agaaccccca ccaaacatct gagtaaaggt
     1861 ttccttaaaa cttttttgaa ttgcctcaaa agtcactttg aaacgagcct tcacttcgct
     1921 atccatacta ttaatagtct ctagcaaaag atttttagct tttgtcagat ctgtcttttg
     1981 acttgttaaa aaagtcaaac gctcatgcac ttcctcatac tgaataatag catcactatt
     2041 aattggtcct agtgcacgaa tagtcttttg taaatggtgt aatttttctt tggcactttc
     2101 taagtgatca atactatttg ttacctcctt tgcgtctgct agtgtcattt gaaaatcttc
     2161 tgataaactt ttagcatagg ctcgtaagcg attagccact tgctctaaat gtgtctctaa
     2221 cttggtttga cgacgaataa atgtgtcatt tttttcgctt tctttggtta ttttttctgc
     2281 tgtttcttct aagcgggcct catagtcctc tatttcaaat cttaattgga ctaaacgttt
     2341 ttgagcacca gacttatgct ctgtggcatc ttgtaactgt ttttgccact ggggtagtct
     2401 ttgaatgctg tcttgactta cgttgttgtt tagtatgctt tcaagtttga gaatattttg
     2461 ctggcattgc ttcagctgag ttcttagacg agattgatta gcttgctcaa atttcttttc
     2521 attaagtaaa tctctttctt gcaaacgagc ttgagataaa gcttggtgaa tgttttgtgt
     2581 tttttgccta atcaaatctt tgttttcttt gatatcatca atatcacaag ttaaggcatt
     2641 ttttttctta gcaatagctg ttaatgcttc ttcaatacga gcttgttctg ccaataaaga
     2701 ttcatcagaa tgagtcgtct gactttgatc aagggcagct aacaaagcct ttgaatcttc
     2761 ttgtttttct tgcaattgct gataagccat ttgagctctt tgttcagcta agcgtgcctg
     2821 gtcaccggct aatttcaatt gtgtcagttc ttcttttttt gctatcaaat cgctttgcaa
     2881 ggcagctact tctttttcag ttatttttaa ttgctcaact aatcgcgtta attcctcact
     2941 gatttgttct aactctggtt tgataaaagt tgtattgctt tgtctattag ttcctcctga
     3001 aaaagaacca cctggtcgta attctgttcc atcaagagta acaattctta ccttatatcc
     3061 taataagcgc gctgcaatat tagcttggtc aatagtttca aagatagcag tactagataa
     3121 aaggttttgg ataatagctg aaagactatc atcatagcga accaatgatt ctgcagttcc
     3181 cagataacct tcacaagtcg ctaattgacg atgatagtgt tctgataatg atctagcctt
     3241 tatagtagtt aaaggtaaaa aagttgctcg tccttggcga ttttttttca aataagcaat
     3301 tgctcttttt gctgcagctt cgtctgttac aataatatgc tgactattag cacctaatgc
     3361 aatttcaaga gctgtttggt aatcagaatc aaaagaaagg tgttcactga ctgcacctat
     3421 gatccctcca agcttttttt gtgattgaag gacagctcgt actcccgcat agaattgact
     3481 atgacttttt tgaatagatt ctaagctagc cttacgagct tcttttcctt ttttttgatc
     3541 caacaagtca aatagtcttt cttgcttcag ttggtaatct ctttctaatt cctgaacgcg
     3601 tttatcacct tcttgataat tttggagcaa catttcgact tgctcttttt gagctttata
     3661 atgagcttga gctttttgag actcgtcatt aagttgatca agcttagtaa caagcagctg
     3721 atattcttga gccttatgtt gacgagcctg tttttctttg tctaaatggg cttttaaagc
     3781 tgtcagctga tttgataagg ccgcctcttt ttgcatcaat aatacaaact cttctcttag
     3841 agtttccatt aattggtcgg gatcacttga aaaacgctct aatgcattgc tcaattcgtt
     3901 taactgttgt ttgacatcac aaagttgttg atcaatatgc aataattgtt ctgtacgctg
     3961 cttttcttct gcttgaaaac catccaattg ttcttgtaac tgttcgaggt gttttttggc
     4021 ttctgccttt ttctctgctt cttggccact ttctagctta accaattcaa tttgcttttc
     4081 caagtcagct attagcttgg ttaattctaa taatgttgtt tgggtttgat ctgactcttg
     4141 actaataacc tgcttttttt gcttaaattt ttggtaatct tcttccatag attgacgctt
     4201 agcgtaataa gatgctaagt cttgttgtaa agcagctaaa gcttcagtat ctttagtctg
     4261 tctttcttga gctatatcaa tatctttgac tagaatatct agttgtagtt gcttacgatt
     4321 ggcatcaagt tctaaaaatt gtttagctac tttagcttgc ttttcaagtg gggccaactg
     4381 cgtgtctagc tcataaataa tatcctctag acggtctaaa ttatcttgag tttgatttaa
     4441 tttaatctga gtttcttttt tacgtgtttt atattttaaa acaccagctg cttcttcaaa
     4501 aatggcgcgc ctttcttcag gtttactatt gaaaatttcc tctacacgac cttgagaaat
     4561 aatggagaaa gaatcacgac caagccctgt atccataaac aaatcatgaa tatcacggag
     4621 ccttaccttg cgaccatcaa tcagatagtc actatctcca tttcggtaaa tatgcctttc
     4681 gacacggatt tctttcttgg cagtttttat aaaatgatcg gaattatcaa gaacaaccgc
     4741 taccttagca tagtttagag gattacggtt ttgtgtccca gcaaaaatga catctggcat
     4801 cttgccccca cgcagatttt tagcacttga ttctcctaaa gcccaacgta aactttctgt
     4861 aatattactt ttacctgaac catttggtcc tacgactgca gttactccct tatcaaattc
     4921 aattttagtc ttgtccgcaa aggacttgaa cccttccaac tcaatttctt ttaaaaacat
     4981 ctaaacctca ctaagttggg caagggcatt tttagcagca tcttgctccg ctaatttttt
     5041 agacttacct aaacctttac taaggacagc accattaaca actatcgata cctcaaattg
     5101 tttagcgtgg gcaggtcctt tctcactaat gacttgataa tcaatagcca catcaccttt
     5161 tgtttgcaaa aactcttgaa gacaagtttt atagtctttt accctttcaa aattcccttt
     5221 ttccacctga ggaatcatga cttgtttcaa gaagcgacgt actgcatcaa tccccttatc
     5281 taataaaaga gcacctaaaa aggcttcaaa taagtctcct aaaatagtat cacgacggcg
     5341 accacctgac ttttcctcac cttttcctag tttgatataa gcgtcaaaag aacaaaatcg
     5401 tgaaaaacct gccaagcttt cctcacgtac aatcatggaa cgtaacttag acatatctcc
     5461 ttctgtcttt ttaggatact ttgcaaataa atactctgaa ataatcaatt gtagaacagc
     5521 gtctcctaaa aattccaagc gttcattatg tgaaacgttt aggagacgat gctcgttagc
     5581 gtaagaggtg tgggtaaaag ctgtttctag taaagtcaaa tcattaaatt gaatatcaaa
     5641 agatgttgag agtaactctt caagctgttt cataaaaaat ccctttcata tttgtcagta
     5701 gaccttattt agtataccaa aaatccacct agaaaaccga ctctaagtgg atttttcgtg
     5761 atttattaaa catcttaaat acccgtcaaa ggaaactttc tcatacaatc aaaagactct
     5821 acactatctg aggggaatgt cccactacag atagtataga gctattttgt ttttagtctg
     5881 aacaactaaa aaactacctt atctttataa tcctcaacac ctttgataaa tagatcagac
     5941 aagccaaaac tacaggctaa tttaagtcta ttgatgctct aaaggataac caatgagagt
     6001 tcattgaact cagaagacaa tacgctttaa gacatcaaaa aatagccctg actggtatat
     6061 caccaatcag cgctactttg catattctct tttagtttct tatctcaaat atcagttaat
     6121 ggacaagcag tatctggaga ggtatcatgg accgtaaagt ctgtacctac tgctaaatct
     6181 gccatagcca gttgattgac catcgtcata tgcgctaact ctttgatgtt attttcttta
     6241 ctcagatgac ctaggtatat ttttttggta ttgtacccca ggcttctaat catggctccc
     6301 gctccatctt catttgataa atgtcctaaa tcagataaaa tacgctgctt caagctccaa
     6361 ggataagagc ctgatctcaa aatttcaata tcatgattgg attcaatcaa gtagccatct
     6421 gcattttcaa taatacctgt catcctatca ctgacatatc ctgtatctgt caacatcaca
     6481 aaagacttat tatctttcat aatccgataa aattgaggat caatagcgtc atggctgact
     6541 ccaaaacttt cgatatcaac atctccaaag gtcaaaactt tatccctttg gaaaatatgt
     6601 ttttgtgagg catcaagctt acctagcata ttgcactcat ccatcagctg ccatgttttt
     6661 tcattagcat agatatccaa atggtatttg cgggccataa cgcctacacc cttaatatgg
     6721 tcagagtgct catgggtaat caaaatagca tccaaatcct caggtttgcg gtcaatttca
     6781 gcaagaagac tggtaatttt cttaccagta agccctgcat caatcaataa gcgtttttta
     6841 ggtgtttcta aataaaaaca atttcctgtg gacccagatg ctaaaatact atatttaaaa
     6901 ccactctcat tcattgatta gtctacatct tcctcccatt cttcatagat ggctgcatct
     6961 ttttcataag gcaagacaat agtaaaggtc gatcctttac catagtcact cttagcccag
     7021 ataaagccat ggtgctgctt gatgatttct ttagcaatgg caaggcctag accggtccct
     7081 ccttgggcac gacttcttgc cttgtctaca cgatagaacc gatcaaaaat aagaggcaaa
     7141 tctgttttag ggatacctag tccttggtct gaaatggaaa taattaattg ggtatctgtt
     7201 gttttcatac ggactgtgat ttttccacca tctggagaat acttaatggc attgttcaaa
     7261 atattctcga taacctgtgt cattttatca ttatcaattt caagccagac agaggtaata
     7321 gggtaatctc ttacaatttc atagactttt cctgtacctg tatgctgatt tttaaccaaa
     7381 tcaaatctgt ttaaaataga agttataaaa gcagtaaaat tagtcatctc tactgctaat
     7441 tgggttactt gattatcaat ccgagacagg tttaaaagat ctgaaatcat acgcatcatc
     7501 cgattagttt catcaagaga aacttttatg aaacttggag caatatcttc tttaagtgca
     7561 ccttcatcaa gagcctccaa gtaggattta accgaagtta aaggggtcct taattcatga
     7621 cttacattag agacaaaaag acggcgttca cgttcttctt tttcttgttc tgtggtgtca
     7681 tggagcacca caaccaagcc cgaaataaaa ccactctctc tcctattcaa cgcaaagcgc
     7741 aagcgtaatg agacaaactc acccatatca tttcggctat taacagttac cactggtgtt
     7801 ttggatacca aatcacggta ggtatatgaa gtatcacctt ctaacaaatc tgtaatgttt
     7861 ttctttagtg cctcttcttt acttaaattt aattgcttgc gagctgtctc gttaatcatg
     7921 atgattttac cagaccggtc tgtagcaagt acaccatctg acatataagc caaaatactt
     7981 gccaagcgat ttttttcttg ggcaagattt tcatgcgtca agcgaaaaac atctgacagg
     8041 tcatttaact ggtctgaaag ctccattaac tcaatgtctg ctttttcgtc gattatatca
     8101 gtatagcgac cattaatcaa gtctcggatt ttatggctca tcatccgaat aatacgtgca
     8161 tttcggtaat cacgcaccgc aagatggata aagtaaaaag caacaaaaac aagtaagata
     8221 aggatcgcta attcaaatgt ggataagttt ccaatgatat ctctagtcat aagatttcat
     8281 gtagtaccca acaccacgtc ttgttaaaat atactcagga cgacttggtg tgtcttcaat
     8341 tttttcacgg agacgacgaa cagtcacatc aaccgtgcgc acatcgccaa aataatcata
     8401 tccccaaaca atttccaata agtgttctcg tgtcatcacc tgacccatat ggttagctag
     8461 atgatgcaat agttcaaatt cacgatgggt caactctacc tcttgaccat gttttttagc
     8521 aacaaacgca tctggtaaaa tctgtaaatt accaatggtt agttcctgtg tacctgaaga
     8581 agcattttct tctgcaacag ccgtttcaat agtttcggta cgacgcagat gagccttgac
     8641 acgtgccagc aattcccgat tagaaaaggg cttggtcacg taatcatcag ccccaatttc
     8701 aagtccaata accttgtcaa actcactatc tttagccgac aacataataa tcgggacatg
     8761 actggtttta cgaatttcct tggctacttc aagaccgtcc aactcaggga gcatcaaatc
     8821 aagaataatt aaatctggct tttcttcttc aaaaattgtt accgcttcgc gtccatcaaa
     8881 agctgtaaca atgtcataac cttcttttgt caaattaaac ttaataatgt cagaaatcgg
     8941 tttttcatca tccacaataa gtattttttt catgtctata cctcagaaag ttcttgtaat
     9001 tgatattaca atttgtgatt tttgtggtta ataaaaaatc acaaaactat atttttctaa
     9061 attatttcta cctgattata ccaaaaattc agcctaattg acaatgacga ctaccgttac
     9121 aaatagagta ctttctaaaa ccaacccttt ataggatgaa tttgacgttt gaattgctta
     9181 gcagattttt tgactctggc aaaactactc ttgttgtggt aagcaaaaag tcctttggca
     9241 ttaaaataag agaacataaa gtcatctttt tgagctctaa accactgacg aaatactctt
     9301 tttggcgatc gaaatccttt aagggtgtcc cttctaaact gaggatcgtg acggctaatc
     9361 ggatcaacat ctaaatccca atgtctagga ccatctgtgc catagttaaa agatgcacca
     9421 ttgacaattc ctttttcggt cactacttct gcatcaactt cattaagaaa aaagcctgtg
     9481 ctatctagaa taaattcggt atgaaaccaa agaagtactt ttatattata ggaaacttct
     9541 tgacttggaa aaatgacttt attatcttca aatcttagtt tattatgtaa cctggcagaa
     9601 tccatcaagg tataatctgg tgcttgccgc cacaaacaag gccctttttt agacctcaaa
     9661 aaaagggcca gagcttgggc gtctgtcatc tcaatcattt tataatggtt tctgatagat
     9721 tgagcttgtt gactagagat gacataacga aattgatgca aacgcttttc aagctcacct
     9781 gcttggctta gtgttttgcc aggaaaagct tgatcaacta agctagccaa ctctttccaa
     9841 aacatatgat ctggcaatag agatggatgg aatcgggtga gtagcgtttg agtttcatgc
     9901 aactgaccac ttagctcaaa tggcatctct accaaatcaa gaagaaacgt tagtaactgc
     9961 ttagctgatt ggttttcttt ttcaataggc catattaccc agaaagttgg agaaccaagt
    10021 cgattatcaa tcataggctc tttagctata gcacgaaatg cttggtttga taaacctgcg
    10081 ttttgatagc atttcaaggc ctgatagcga tctaagatag cttgtttcat ggccttctcc
    10141 tcatcttttt tgaccatatt ataacacatc taaagctgaa tcgtcacttg tatctcacta
    10201 taagcaaaac gaaacctgaa gtggttaact aagccactgt ttgggtattt tatttaaaag
    10261 aacttctcga ttaattttac cattatcttt taaaggcaaa caatcaatca caagatagta
    10321 cttgggaagt tgtccagagt ttaaataaag agctaaaaag tctttaatag gtgctaggca
    10381 atccttctta gtcaaaacta atactaatat tagggtttcg ttttctcctt ttcctatctt
    10441 taaagcgtgc gcttctttga cgtttagcgc ttggtgagcg agttcaacta ggctaggcag
    10501 gtggcatttc actcctcgtt gattaaccca gtcatcttgt cgcccttcta aaattaaacc
    10561 cgctgggctc atttttccta agtctgagac actgtatggt tgtgacattc cttctacact
    10621 ataaggagtc tctacaaaaa tttccttatc tttgaaactg atagacacat caggaaaggg
    10681 ctgtcctacc aaaccattaa ttttgacagc agctctgcca ttacaccacg ttataaaaga
    10741 taattcacta gccccgtaga aaatgacaat ttcaagctga ggaaattttt tgtaataatg
    10801 tcttagtaat tcttgtgata tcatttgcga agaggtcaat aagtgagtcg cagtcatgtt
    10861 gttcttagtc aaataaggta gcaagcgatt taggtaggtc ggtaaaaggt aaaggtgact
    10921 cacctttttt gcttgccata agcttaacca cgttttcaaa gacagctttt ggcttaaaac
    10981 cagacatccc ccggcccata gttgagctaa tgctaagtta agattgccag taaaactaaa
    11041 actaccatgt aagaatagac aactattacc agtcatacca aacatcttat tttgataatc
    11101 aaaaagtctc gtccaagttg atagacaacg ccaaaataat tttgctttgc cagtcgttcc
    11161 cgaactcaaa acagcaaaat cagctttttc aagaagctca ccatcgacgt gttttatttg
    11221 ctgctgaaat gtacctgaga tattagggtg taaaatgata ggacagctgc cttcttttaa
    11281 tcctcgtaaa aaagagagta actgattaag atagcgacta tgactgatga tatatggtac
    11341 actgtctttt attgtctgat cctttattaa aaccgcttgc catagctctt gataagtcaa
    11401 gcttatctga tcggctacga tagctttttt atttgggcat tgctttgccc aatattctag
    11461 ctttgtcagc atgactaaac tccttatgat attttagtaa aacagcaaac ccttggccac
    11521 cagctgctgc tatagcagct attccatagt gtccattttt aatctctaaa gccctcatta
    11581 agtgcaatat tataatggct gctgaggcac catagggatg accataagct aatgcaccac
    11641 caaatatatt atagcggtcc aataaatctg ggtaatgggt ttcaaataga ccatcaataa
    11701 cggcaaaggc ttcgttccat tcaatcgctg tcatatctgc catccctaga ccatgttttt
    11761 ccaaaaggac ttgactagcc ttaatcacca ttaaagggct acgctgtggg tctcctgcta
    11821 cttctaccac atcaatcagt ttaaaagctg aaggctgact acttagctgt aaaaaggcag
    11881 cagcatcatg ggttaggcag gcattggctg cactaatcac gtgatcttct cctaagatag
    11941 ggggtacctt tgacaacacc ttacttgaca agcgcggtcg aataccttga tcactggctc
    12001 ctggcaggtc tagaataaga tcagctaaca gggcttgctc ctggcaataa ctagcctttt
    12061 gatgacttct caatatccag tgattcaaat actcctttgt aaagccatgc tctcttgcca
    12121 ctcgttctgc cccttcaatc atcgcaaaag ggctgatact atctggagaa aactgagcta
    12181 ccttgtaggc tccttggcgc caatcagctg aagcatatac cgattcaggt tgtaaggagc
    12241 tgctttcaat ccctcccact aaaaggttgc ttgccatacc tgccttgatt ttagcataac
    12301 ccacggaaag agctgcacca gctgatgcac actgcatatc aaccgtcaaa gcagagacag
    12361 attctcctaa atgagaatac agggtcatca agcgcccaat attaccaccc gttccgacgg
    12421 cattgccaca aatcacttgg tcaatgggaa ctggatactt attttgtaaa gcattgatga
    12481 gctttgctcc aaggatttct ggttgttctt tagcaaattg tttccctact aaaccgatag
    12541 gggttctaag gcctgcagca atataaacat ccgtcattat attgacctcc tttattttcg
    12601 atgtccttaa atggttatta tataattatt tctgatggtt ttcttttttg aactaataac
    12661 tgctaaaaat acacctaaat taatttagag aatctcttta gtctcgctag tgtgccatca
    12721 ataaaatcta taaaattctc taacgtcatt gaaatgtcaa gtcccacaac tattgtcgta
    12781 gaagtcactt actttgttgc tttaacattc aaactgtaac ctttgttttt gatacagggt
    12841 gactttatta tactggaaaa ccattcctaa gaaaagaaaa tcttatatag aataaagaat
    12901 tagacaccat aaaaaagcta agctgtgaca cttaactttt ttatggtatt gacaaacctt
    12961 gtctttacta tttattgata gttaatgcct ctaactaaaa taaaagccat gtctgtatca
    13021 gcctgcaagg catctgctaa gctggtatcg ttactagatt tgacaggtct cataaaggca
    13081 aaagatctca aagttccata aacgttatct agcaattgca tgcaaccact tgaaatatat
    13141 ctgcttatgt tattttaccg cccttaattt agaccaatct gctgatgatg gttccaaaca
    13201 atgcctctag gaacctgcac tttcataagc atctaggccc catttccaaa gcttaagcga
    13261 caaggccaaa accagtaacg acaccactac caagcctcca atattaaaga gcaggtgctg
    13321 acctgttaaa aaataagaag cagggtaata agctgtaaaa gcaaagggaa tgacaaaact
    13381 gattaaccac cgcaaaaagg aatggtaaat ggacataggg tacttggaaa agtcattaaa
    13441 catgtaaaaa atatagataa ctgccccaga ctgcttggtc caaaaagaaa tgctggcggt
    13501 cgcaattttt aaagaggtgt aaatcaaggt cgcaaaagga ataaccaaaa taaacaaaag
    13561 caccttagga agagtccata cgatactacc agccgtggtc actaataaga taaccccaac
    13621 caataattca cccagggcat ccacttgaaa tgtctcaacc aaaacatgaa acaaaggact
    13681 aattggtctg gtgaggtact tgtcaaattc tcctttgcgg acaagccgtt gccctaaagc
    13741 ccaaagattg tcaaaaaaga ggtgatcaat tccctttgga atcaaagaaa agccataaat
    13801 aaaggcaatt tgttcaaacg tccagccttc taaagaaggg atatgttgga aaagtaccga
    13861 taaaaagagc agattaagac cctgagtgag aaaaacacct agcactccca ccacaaaatc
    13921 aaccttgtat tccataattt gtttgaggta ttgtttgata aaaatagcgt gcatacgtct
    13981 caattttgcc atctcaccct ccttgaatcg ttaaatggta ctgaaccttt ttccagatga
    14041 cttgcgataa gactaccatc accagtaacc aaaagatttg caaacttagg gcaaccatta
    14101 tctgactaag gctgtatttc ccaatgacaa tcataactgg cgtgtaaacc aaagaggaaa
    14161 acggtagaaa actaagcact atagaaacca ttttaggaaa aaaagccaat ggaatcaaac
    14221 tgcctgacat aaaggcaacc aaggcatttt tcaataaatt agacccccaa aggtttttaa
    14281 agacaaatgc tgaaaagcca aaacaaatgt tgaaataaaa attgattaaa aaagctaata
    14341 aaaggctaac taaatacaga caactgctgg ctaggacttg caagatagac agccccgcca
    14401 tgactttaat accagataag accactaaaa aaggaaagcc gacactcatt agcacaatcc
    14461 agcgaaaacc aatttccata aagaggtaag aggctgcaaa atgaactggt cgaagcaggc
    14521 gcatgatgat agaaccatct ttcacttctt cgccaatcat aaaggagctg tctgatttgg
    14581 tcagtaaagt ggtcacaaaa ctcatgataa tgtaaaaggt catgtcagac agagtaaaac
    14641 cattgattaa ggattgctta gacgaatcaa aaacagcctt ccagaggtaa taagccacaa
    14701 aagcccccat gacatctcca atacgataca aaaagaaatt aacgcgatag gttattaatt
    14761 cctgaattcc tgcactgaga aagggtctat aacgtttcca aaatgaccac atcttaaagc
    14821 tcctttcggt agaaacgacg aacaatatcc tcaatatcaa catcagtcat cttcaaatcc
    14881 ctgaccgcaa aatcagccat ggttttttga ataatgtccg ctgtttgata gcgcgaactg
    14941 tcatattgaa tgtctaaact aagctcatgc cgttccactg tgatgtcagg taagcccata
    15001 aactgtgaga ccacctgctc ctgccctggc ctcaactcaa aagacagact cttcattttt
    15061 ccaaagcttt gctttaattg ggtcaccgtt ccatcaaaga tttcttgccc tttatcaatc
    15121 atgataatcc gatcacagag ctgttcaata tcactcaaat catgggtcgt cagtaaaata
    15181 gttgtctctt cttcttgatt aatttgagta atggcacgcc gaatgttgtc cttcacagaa
    15241 acatcaagtc caatcgttgg ttcatctaaa aacaatactt taggattatg caacaaggaa
    15301 gcagcaatat cagctcgcat ccgctgaccg agtgataaga tccggacagg atccttaata
    15361 aactcattca ggtccaaaac ctcatttaaa aaatccatgc gcttgcgaaa ggctttttca
    15421 ggcacatcgt aaatttcttt taaaacgaca taggtctctt gcaaggccaa atcccaccat
    15481 agttgtgttc gttgaccaaa aacagctcca atgtctctca cataatcttg acgattatct
    15541 tgtggaatct ttccgttaat gcgacagtaa cctgatgtag gctttaaaat acctgttaac
    15601 atcttaatcg ttgttgattt tcctgcacca ttggctccaa taaaacctaa aatttgccct
    15661 ttgggtacct caaaagataa gtccttaacc gcctcaaaga tttctctttg gggatgaaca
    15721 aaggacttca aggctccctt taatcctggc tctttaatgg ttttggaaaa atttttttga
    15781 aggtgggaca cttctatcat gaccatttac cattcctcgt ttctgttatc gtcttatcac
    15841 cgttactaaa caatttatta taacaccatg aaaaagactg tgcaaccgtt tgcttaattt
    15901 tttaagaaag aaaaagaagc ccataaggac ctctttttgc cattgattaa gcttgtgcat
    15961 ctggacgtga cttgcgagca atgtctgcca agatgttttc cacaaattct tccacagatt
    16021 cagtgtgagt cgccttacta ccatagcggc gaacattgac tgatttgtct tccatttctt
    16081 tgtccccaac aattaattgg taaggaattt tgctggtttg agacgcacga atcttgtact
    16141 gcattttttc attgcggtca tcgacatctg cacgaacacc acggtcacga agggtttttg
    16201 ctacttccca agcatagtca atgtgggctt catttgaaat tggaatcacg gttacttggt
    16261 gaggtgccaa ccaagttggg aaagcaccct tgtaagtttc aataaggata gcagtgaaac
    16321 gttccatagt tgagataaca ccacgatgaa tcatgactgg gcggtgttct tcgccatctg
    16381 caccaatgta tttaaggtca aaacgttctg gcaacaagaa gtccaactga atggttgata
    16441 gagtttcttc gttaccaaga gctgttttca cctgaatatc aagcttaggc ccataaaaag
    16501 ctgcttcacc ttctgcttca aagtaatcta cacccatctc atcaagtgca gctttaagca
    16561 tactttgagc attttcccac atctcatcat tgtcataata tttatgagta tcgttagggt
    16621 ctcggtatga caaacgaaaa cgataatcag tcaagttgaa gtcagcataa acatcaatga
    16681 ttaattgaag ggcacgttga aattcttcct ggatttgctc tggtgttacg aaaatgtggc
    16741 catcattcaa ggtcatttca cgtacccgtt gaagtcctga tagggcacct gatttttcgt
    16801 aacggtgcat catgccaagc tcggcaatac gaataggcaa ttcacgataa gaacgcacat
    16861 gatttttata cacttgaatg tggtgtgggc agttcattgg acgaagaaca aactcctcac
    16921 catctcccat atccattaca gggaacatat cttcttgata atgatcccaa tgacctgatg
    16981 tcttgtacaa ttctacagaa gcaagtggtg gtgtgtaaac gtgttggtag cctgatgcta
    17041 attctttatc tgtgatgtag cgctcaagtg tacgacgaat agtcgctcca tctggtaacc
    17101 aaaatggcaa gccttgacca acttcttgac taatcatgaa caagtcaagc tctttaccaa
    17161 gcttacggtg atcacgttct ttggcttctt ccagacgagt caagtaagct ttgaggtctt
    17221 ttttatcaaa ccaagctgtt ccatagatac gttgcatcat gttattgtcg ctgttaccac
    17281 gccagtaagc acccgccaca ttgagcaagt ggaagacttg gatacggcct gttgatggca
    17341 catgagggcc acggcaaaga tccacaaatt caccttgacg gtaaaccgtc aagccagcac
    17401 cagcatgctc attaatcaat tctaccttgt aaggatcatc tttgaacaat tccaaagctt
    17461 cttctttagt cacttcttca cggatacatg ggtaattttc tgtcacgatt ttttgcattt
    17521 cagcttcgat acgtggcaaa tcttcgtttg aaatttggcc ttcagcatta tctgtatcat
    17581 agtaaaagcc ttctgcaatg gcagggccca cacccaaatg aagatttggg aacaagcgtt
    17641 ttgcagcttg ggcaaataaa tgggctgcag agtggcgaag cacctcataa gcatctttgt
    17701 ggtcaggtgt cacgatttca atactgccat cttcttcaat ggcacgagtg gtgtcaatga
    17761 gttgatcatt gaacttacca gctaaagctt ttttagccaa tgatttgctg atggactcag
    17821 caatgtcaaa cgttgttacg ccagattcaa attcacgcac ggcgccatct ggaaaagtaa
    17881 tcttaatcat ttgctttctc ctttaagtca gttaagattt ccactaaaac atggatagta
    17941 agacaaatta gggacaagag gttagtgaat agctcaatac caccacgtag aagaacaata
    18001 ccttattcac gaatctaccc tccctagtcc ttaaaaacaa ggctaatccc ctccaaaaca
    18061 aaaaaactga ccgcatccca aaggacgcaa tcagcgtggt tccaccttaa tttatgcagg
    18121 acaaaaaaca tgccttgcac ctctagtggc gataaggggg ccaccctttt atgtttgcat
    18181 aaaaaccagg aaggagtatc agattagcta tccttgtgct ctttccacca accagcactc
    18241 gcttaaaaga ttctgtccaa tctaacttgt cttcaagata attatagcaa gttttcaaaa
    18301 atttacaagt cttaatccag aaaatctttg atagcatgga ccagcttgat aggagccttg
    18361 actactttta ctgaggtgat agctgtgacc ttagcagcac gtttaggcaa gtgaatagca
    18421 ccttgcacta attttagaga actactttta ccagaatgat taagataaag actcagcttt
    18481 tgagcttctt tgctatttct agcaattaac gtatctaaat agaacgtgta aatagatttt
    18541 ccaaagtgct gtgctgagat ttcataacgt ttttttgcta ataaccgttt atccataact
    18601 ggtgttttta gtatggcatc aataacagca tcagttaaat ctgtttcagc gtaataaaga
    18661 gtgccaaaca ttttatcagt caccacatca tctaaataag gattgccatg agcaataata
    18721 ggagtgccac tagccaaact ttcaatatag gtcaagccct gagtctcact agttgatgct
    18781 gagataaaga aatcacaagc cttatagtac agagcaacct tatcatgagg caccatgcct
    18841 gtaaaggtca cgtgtttgtc aacctctaac tgcatcgcca agtgtttcaa atcttgcaaa
    18901 tagggaccat ttcctacaat aataagcttt atcttggcat tttcagccaa aatagctggc
    18961 atctgattga tgatagcttg aatatttttt tcataagaaa tccgtgacaa actcaataac
    19021 atggtttcat caccagcaat gcccaattct gcttttaagt tggttacttc ttctgctgtg
    19081 atgtcatcac gaatatattt ttccaaagga atgcctgttg ggataacccg cttagggata
    19141 gtcacttcgt aaccttctag aagattgagg acaatcctac ttgggcagat aaccccatcc
    19201 aaatccttca aatagcccct aagaagaggt ttgaccatac ttggtcgaat gatttttccg
    19261 ttggcaatat aactcacgta gtcctcatat tgggtatggt aagtatggac aacaggaatt
    19321 cgcaaagctt tgcctatcat tttccctaat aagcctaagc taaactcagt ttgcgtatga
    19381 ataatatcaa gattatagtg ttttgcaatt ttgtatgacg aaatgaggcc acgataaacc
    19441 acacgtctat ccgtaaatga cacaaaagga acacttggca gtcgaataat ggtcgggtct
    19501 tcaaagcgtt tgacatctct atcagtagtg gtgaaaatat aaacttcgtg accttctttt
    19561 tctagctctt cttttaacgt acgaatacta gtagcgactc ctgaaacttg tggaaaatag
    19621 gtatctgtga atagacctat acgcatctta taactccatt acttttttat agacatctac
    19681 taaggcatgg ccaaccgttt ctaggcgacg actctgggca accttgtaac cagcttcaac
    19741 tttgttgctg gcaccagaaa agactttttt cagagcttct ataaaacctg gtatatcggt
    19801 tgctaattcc gcactacttt gatcaaccca tccgtagtaa actggtatat cacgtaaaac
    19861 aaggtgctgg cgactggcca aggcttctaa gacaacaatg ccttctgttt cttcacgact
    19921 tggaaagaaa aaggcatctg caccagtcat ggcaccttca taaacatccc ctttaatgta
    19981 tcctgggaaa ataagatttt tcgggtggtt accattgacc atttggcgaa cttgagcagg
    20041 aatgacccat ttgttggtct cgccaaacca gataaaacga acatctggca tagcttgggc
    20101 aactttgaca aagtcatcaa ttcctttcct cagaaaaaat aatcctgctc ccataaccac
    20161 tttttcaccc tctttaatgt caaagtagcg acgaaaagct gcttcctttt tagaatctgc
    20221 tccgtactgc tccaaatcaa tcccatttga cactgcaaaa ataggtgact tcactccata
    20281 actctcaatc aaagacttag aatatagggt aggggtaatg atagcatctg ccttattgta
    20341 aaagtgacaa aggtattttt taaaccaagg agataataga tttgaaaaaa taaaagaatt
    20401 tctaaaatct tcttctgtag aatgcccatg catgataacc ttcttaccag ctttttgtgc
    20461 ttttatcatc agcagccaac tttttaaacc ataggtattg agatgaacca aatcataagt
    20521 ttctcttgga ttagtcgtaa aatgttgacc aacaagtgac aaggctttag cctgatgctt
    20581 aatcgctcga ccaattcctg attttcttag ataattttct gcttctaaat acaataagac
    20641 tttcataagt tctattatag ctcattttat agtatttttc actaagacat gcaaaaatca
    20701 gccctaaggc tgattttagt attgaagaaa cagtctattg tgatactttt tgttagatgg
    20761 tgctcataag tcacagttac ttagttgtcc cacgtttttt aataccatga ttcaaaagaa
    20821 tttctttttc ttccaactct tctttgttca tgattttagt caacatccgc atgctaacag
    20881 cacctaagtc ataaacaggt tgactgatag aactcaaatt gggacgagtg tattgaacca
    20941 ctggtgaatc gttgctggtg atgatttcaa agtcctctgg tacgcgttta cctgcttcaa
    21001 acaagccgtt taaaaggcct gctgccaatt catcttcagc cacataagcc gctgttgctc
    21061 ctgagttaat gacgcgctgc gccaattcaa atccttcttt ataagaatag ttcgcttcaa
    21121 aaacaagacc ttctttgaag tcaagcttat tgtgcttcaa cccttctttg taccctgcta
    21181 agcgcacttt accattgata tcatcaatga gtggtcctga cacaaaagcg atacacttat
    21241 gattttcagc taaaatatca acaacgtttg acaccgcagc tctatagtca atgttgacgc
    21301 ttggtaattg atgatcaaga tctacagttc ctgccaaaac aactggagta cgagagcgtg
    21361 aaaattcggc ccggattttt tctgtcaagt gatgccccat aaaaataata ccatccactt
    21421 gcttggcaaa aagggtattg acaacattaa cctccttgtc atcatcttca tcactggagg
    21481 caagcacaat attatatttg tacatagcgg cgatatcgtc aataccctta gctaagatag
    21541 aaaaataact atttgcaata tttggaatca caacgccaac ggttgttgtc tttttgctgg
    21601 cgagaccacg cgcgacagca ttgggacgat agtcaaggcg atcaataact tctaaaactt
    21661 tcttacgtgt attttcctta acatttttat tgccattaac aacacgacta acggttgcca
    21721 ttgaaacacc agcttcacgg gcaacatcat aaattgtaat ggtatcatct gtattcattt
    21781 tttatcttcc tttctatttg aaaatgacgc tttcaaaaag tattttagca tgatttgtaa
    21841 ccactttcaa gtgttatagg ttaatttttg aaaaagtttt caaaaattaa ctcgaagctt
    21901 gattttttaa gctttttttg aaaaaatagt aagtagaaag aaggttagcc tatgacaaaa
    21961 ttagaccaaa tacgtttgta tcttgaccaa aagggagctg aattggcgat tttctcagat
    22021 cctgttacga ttaactattt aactggattc ttctgtgacc cacatgaaag acaactgttc
    22081 ttgtttgtct accatgattt agcccctgtg ctttttgtac ctgcccttga ggtggccaga
    22141 gctagccagg ccatatcatt tcctgtgttt cgttatgttg actctgaaaa tccttgggaa
    22201 aagatcaagg ccgttttacc aaatacagca gccaaaacca tttatgctga atttgaccac
    22261 cttaacgtca ataagttcca tggcttgcag actatctttt caggacaatt taacaatcta
    22321 acctcttatg tccaaggcat gcgcctcgtc aaatcagctg atgaaatcaa taaaatgatg
    22381 attgccgggc agttcgctga taaggctgtt caagttggtt ttgacaatat ttccttagat
    22441 gctaccgaaa cagacgtcat cgctcaaatt gagtttgaaa tgaaaaaaca aggcattcat
    22501 aaaatgagct ttgacactat ggtcttaact ggaaataatg cagccaatcc ccatggcatt
    22561 cctggaacaa ataacattga aaacaatgcc ctacttctct ttgacttagg tgttgagacc
    22621 ttaggctaca ccagtgatat gaccagaact gtggctgttg gtcagccaga ccaatttaaa
    22681 atcgatatct acaatctctg cctagaggca caactagcgg ctattgactt tatcaaacca
    22741 ggtgtaacag ctgctcaagt agatgctgct gctcgtcaag tgattgaaaa ggctggatat
    22801 ggtgagtact tcaaccaccg cttgggacat ggtatcggca tggatgtcca cgaatttccc
    22861 tccatcatgg ctggcaatga cttggtcctt gaagaaggta tgtgcttctc tgtggaacca
    22921 ggcatttaca ttccaggtaa agttggtgtg cgcatcgaag actgtggcca tgtcactaaa
    22981 aatggctttg aagtctttac ccatactcca aaagagttgc tttattttga aggctaagcc
    23041 cctaccatct ggttaaacaa accctcgcga aaggaaggta ttcgtatgga tcaaaccatt
    23101 catcaccaaa tacagcaagc actacacttt aggacagccg ttcgtgttta taaggaagaa
    23161 aagatttctg atgaggattt agcccttatc cttgatgctg cttggttaag cccttcttct
    23221 gttggcttag aaggctggcg ctttgtcgtt ttagacaaca agcctattaa agaagaaatc
    23281 aagccctttg cctggggggc ccagtatcaa ctggaaacag ctagtcactt tattctttta
    23341 atagccgaaa aacatgcaag atacgatagc cctgctatca aaaatagcct tttacgacgt
    23401 ggtatcaaag aaggtgatgg tctcaacagc cgcctaaaac tctatgaatc tttccaaaaa
    23461 gaggacatgg atatggcaga taatcctcgg gcactctttg attggacagc taaacaaacc
    23521 tatatcgctc ttggtaatat gatgatgaca gctgctcttt tgggcattga tacttgccct
    23581 attgaaggct ttcattatga taaggtcaat catatcctag ctaagcataa tgtgattgat
    23641 ttagaaaaag aaggcattgc tagcatgtta tccctaggct atcgtttgcg agatcccaaa
    23701 catgctcaag ttcgtaagcc taaagaagaa gtgatttcag tcgttaaata aggagattaa
    23761 aatgaaagca ttacatacct gtatccgcgt caaagacctt gaccagtcgg tagcttttta
    23821 cacaagcgcc ttccctttta aggaaaacta tcgtaaagat tttccagata gtcaatttac
    23881 tcttgtttat ctggctttag aaggagaaag ttatgaatta gaattaacct acaattatgg
    23941 tcatggcgac tacgacttag gaaatggcta tggtcatatt gcccttggct ctgaacattt
    24001 tgaagcagac cataaaaaac atcgacaagc aggttttcca gttaccgata tcaaagaact
    24061 ggctgacaaa tctgcccgct attatttcat tcaggatcca gatggctaca aaattgaagt
    24121 cattgattta aacaactaat actattaaca acagaagctt taaagcttct gttgttttat
    24181 tttttaacct gacgattggg ataatctcat tattaacaga gttttgaaat atctcagctt
    24241 ttgtgttaca attgccctaa aattccattt gaaagaaaag tctatgacac tactatctat
    24301 cattgtcccc tgctttaatg aagaagcaaa cattctccct tattttgaag aaatgcatca
    24361 actagaaacg tccatgtcca accaacttgc ttttgaatac atttttattg atgatggttc
    24421 taaggataac accttaggta ttttgcgtga gctagctgct cgctttccaa acgtgcatta
    24481 tctgtctttt tcacgccatt ttggcaagga agctggactc ttagctggac taaaagaagc
    24541 caaaggcaat tacattactg tgatggatgt ggatctgcaa gatccacccg aacttttgcc
    24601 agttatgtac gctaagctaa aagaaggtta tgacatcgtt ggcaccaggc gccaaaatag
    24661 acaaggagaa ccactaattc gttcaatgtg ttcgaatcta ttttatggac tgatcaaaca
    24721 cttatcagat actgaaatgg tcaatggagt tcgggattat cggttaatga ccagacaagt
    24781 cgttgatagc attcttgagt tgggagaggt taatcgtttt tcaaaaggga tcttttcgtg
    24841 ggttggttat cgtatcacct atcttagttt tgaaaatcaa aaacgcaaat atggaaaaag
    24901 tcgttggcat ttttgggagt tgctccgata ttctttagat ggctttatca acttttcaga
    24961 aatgccgtta accattgcta cctggacagg gactttcagc tttttgattt ctattttcgc
    25021 catcttattt atcattatca gaaagatact ctttggtgat cctgtctctg gttgggccag
    25081 cactgtctct attattttat tcatgggagg cattcagctc ttttgcatgg gtattattgg
    25141 aaaatatatt tcaaaaatat tccttgaaac taaaaaaagg cctctctata ttatcaaaga
    25201 aaaacattaa attaaaacat ttttctcatc aatcgtttcc tactccttct gtgcgcgaag
    25261 ctttcttttt aagcccgtta taccaaatga taatgacctt tccaaaatag tatcaccttc
    25321 cttaacactt taagtagaaa aggaactatt aggttgagcc tttttgcaaa tcctagcgac
    25381 taatgttata atcgtcatac tattgaaaaa ggagttcttt atggagtgga ttaaattaat
    25441 cggtattgtg attatcgtgt tagggtttat tttaaaatgt gatgctatcg ctaccgtagt
    25501 tgttgcagga cttgttaccg cgctggtttc aggaatttcg tttattgatt ttctagatat
    25561 tttaggaaaa gaatttacca atcaacgttt gctaaccatt ttcttcatca ctttaccgct
    25621 tatcggcttg tcagaaactt atggactgaa acaccgagct actcagttga ttcaacgtgt
    25681 tcaagccctt accgtcggcc gtttattgac tctctacctt attattcgag aattagcagg
    25741 tctcttttcg attcgactag ggggacatcc acagttcgtt cgccccttga ttcaacctat
    25801 gggagaagct gctgctaaag ccaacattgg agaagagttg accgatgcag aaaaagatga
    25861 tatcaaagct atggcagctg ccaatgaaaa ctttggcaat ttctttgccc aaaatacctt
    25921 tgttggcgca ggaggtgtcc tacttatcgc tggaacttta gaacagcttg gctatgatgg
    25981 taaccaagct aaaattgcat tttcttctat tttaattgct attatctcta ttattatagt
    26041 tgctatttac aattacctct ttgagaaaaa aatggaacgt caacatcaga aaggagataa
    26101 ctaatggcta acattgcaaa ccttgtttta gaaacgatat atatccttat cggcttgcaa
    26161 ctgtttcaca cagcctactg cacctttaaa gataaaacca accctgtcta ttttgggaca
    26221 gctctgttct ggggattgct gggtgttacc ttcgttggcg gtgccttttt gcctaataaa
    26281 gttatcggtt ttatcgtgat tgtcctagct cttttaacct tgtttaagca agttcgtatt
    26341 ggaacattac cagcctttaa tgaacaaaaa gctgaagaaa gtgctcaccg cattggtaac
    26401 tggattttct taccagttat gttaatggct atgatttctc tacttcttgc cttgatcctt
    26461 cctgatttca gtaaaagtgc cattgggatt gctggtatct tagccactat tgctatttta
    26521 ataatcacta agcaaaaacc atctgctctt ttagctgaaa ataatcggat gaaccaacaa
    26581 gtgtccacaa gcggtatttt gccacagctc ttaggagctt taggagctat ttttgcagct
    26641 gctggtgttg gtgatgtgat tgcttctctc attcgggaga ttgtacctgc tgatagccgc
    26701 ttctttggcg ttctcgctta tgtgcttggc atggttattt ttactatgat tatgggaaac
    26761 gcttttgctg cctttaccgt tattacaacc ggtatcggtg ttccttttgt ttttgcttta
    26821 ggagctgacc ctattattgc cggtgcttta gctatgactg ctggtttttg tggtacctta
    26881 ttaacaccaa tggcagcaaa ctttaatgcc ttgcctgttg ctttgatgga gatcaaagat
    26941 cgaaatgcag ttatcaaaaa gcaagctcct atcgcccttg ttttaattat tagtcacatt
    27001 gccttaatgt atttacttgc ttattattaa catttttgct aagttagtag cgtcagttat
    27061 tcattgaaag gacattatta tgaaaattct tgtaacaggc tttgatccct ttggcggcga
    27121 agctattaat cctgcccttg aagctatcaa gaaattgcca gcaaccattc atggagcaga
    27181 aatcaaatat attgaagttc caacggtttt tcaaaaatct gccgatgtgc tccagcagca
    27241 tatcgaaagc tttcaacctg atgcagtcct ttgtattggg caagctggtg gccggactgg
    27301 actaacgcca gaacgcgttg ccattaatca agacgatgct cgcattcctg ataacgaagg
    27361 gaatcagcct attgatacac ctattcgtgc agatggtaaa gcagcttatt tttcaacctt
    27421 gccaatcaaa gcgatggttg ctgccattca tcaggctggg cttcctgctt ctgtttctaa
    27481 tacagctggt acctttgttt gcaatcattt gatgtatcaa gccctttact tagtggataa
    27541 atattgtcca aatgccaaag ctgggtttat gcatattccc tttatgatgg aacaggttgt
    27601 tgataaacct aatacagctg ccatgaacct cgatgatatt acaagaggaa ttgaggctgc
    27661 tatttttgcc attgtcgatt tcaaagatcg ttccgattta aaacgtgtag ggggcgctac
    27721 tcactgactg tgacgctact aaacctatta aaaaaacaga gatatgaact aactctgttt
    27781 tttttgtgct aaaaatgaaa gacctaggga aacttttcat aggtctttct caattgtcat
    27841 cttaatctaa tactacttct aacatcagcg ggtatagttt accagtaatt aagaaacgtt
    27901 gttgatctaa atgagcaatc ccattcaaaa cattaaggtc agggtaatgg gacttatcaa
    27961 gatttaaggc ttttaacaaa ggactaatat cataggtggc taccaccttt ccagaatcag
    28021 gttggagttt gacaatagta ttggtttgcc aaatattggc atagagataa ccatctacat
    28081 actctaattc gttaagcatt gagatgggga cactttctat agcaactagt acggtatcca
    28141 ataaagcaaa atctttgggg tctcgctttt gcaaaaaagc atttccacta gtcatccaaa
    28201 gacactggtt ttccttatca taggctaatc cccagccatc tccttcaaat ggataggccc
    28261 ctaaacaatt gcaggtagcc ttatcaaact tgtaggctac accctcttta taggttagta
    28321 accaaaaata atcctcaaca actgttagcc cttctgcaaa aactgtatct ggaaaagcta
    28381 ttttttctga aaagatctct tgagtaaggt catacacccc tacttttgag aaaccataac
    28441 gaccggcact aagtaatata tgattgttgt tgagttgttc taatccctgc gtgtataagt
    28501 tgctatcata agaataagtt cgtaacaaac aaacctgtcc tttagttatc ataatactca
    28561 ttcaccttac cttgcattgt agtgtttcat ttgtttttta atatctcttt cctgatcacg
    28621 gcgtttaatg gtttcgcgtt tgtcatactc gtgtttccct ttagctagac caatcagaac
    28681 tttagcaaag ccatccttga gataaacttt gagaggagcc aaagtcatgc cagatccttt
    28741 aagttcattt gctagatgcg taatctcacg ttttttgagc aacagtttgc gggtccgttc
    28801 aggatcagcg ttccaaatat taccttgttc aaaaggtgca atatgcacgt tgaccaacca
    28861 cgcttcccca ttcttaattt gggcaaagcc atctttcagt tgaatacgag ctgcacgaac
    28921 acttttaatc tcagttcccg ttaagacaat ccctgcttca acggtttcaa caatgtgata
    28981 atcatgtcta gcctttttat tttgcgccag tatatgacct tcaccttttg ccatagttaa
    29041 ctccttttac gactcttctt ttttgcttgt tctttgtaaa atggtttttt agaccctttt
    29101 ttagttttac ccttggtttt tgccttggct acttctttag gttctttttt ctttatccct
    29161 ttagatgatt ttgaggattt acggcgatct cgtcgactag ctttatccga catcttgatt
    29221 ttttcaacca catcaaagtc gctaggtaaa tactcaaagt caatgtcacc agtttccttg
    29281 tcagccttaa ccaatttcac acgaataggt tgaccaactt taaagacttt acctgatttt
    29341 tcaccttgaa ggcttagcgt tctttcatta aagtgatagt attccggtaa gctagtaata
    29401 tgaaccaaac cttcaatcgt atttggcaat tctacaaaaa aaccaaattt aacgacactg
    29461 gccacgatac cgtcaaattc ttcacccaca tactctgcca tatactcagc ttttttcatg
    29521 gcttcaacca cgcgttcagc atcaatagca cgacgctcta actgtgaaga agatgttgct
    29581 aattctggaa tgatctgagt aaaatggtcg cgcttttctt gactaggttg actgtactca
    29641 cgaaccatgc ggtgaaccaa caagtcaggg taacgacgaa tcggactggt aaagtgagtg
    29701 taatattctg cggccaaacc gtaatgccca tgattatgtt cagaatatct tgcctgttgc
    29761 atagagcgta agagcatcat gttaagcact tctgctcctg gttgaccttc gacttttgcc
    29821 ataaaggctt gcaaggcttc ctgagaaatc ttgttggctg ttccttgaat gtgaatacca
    29881 aaggtgctag cgtaatcaat aaattgttga agtttttcgg cctttggttc ttcgtgaata
    29941 cggtagataa acggtaactt agcttttgca aaatgttctg ccacacactc attggctgct
    30001 agcataaagg actcaatcat ccgctctgca attccccttt gacgaagcac cacatcaacc
    30061 ggtattcctt tgtcattaac aataacttta gcttcttgcg tatcaaaatt caaggcgcct
    30121 cgttttgacc gcatagcttc caaaatccta tgcaaagcca ccatgagggt cacatcatca
    30181 gcaatgctag cgaattcttg gagcgcttct tcatctcctg caatcatgtc attgaccgta
    30241 ctatacgtca ttcggtaagt tgtcttaatc actgattgac agatttgata attgaccaca
    30301 tgcccttgag aattaatttc catcaaggct gactgggtca aacgatcaac gttagggttc
    30361 aaagagcaga tgccatttga caaacgctct ggtaacatcg gaaccacacg atcggtgaca
    30421 tagacagaag tgccacgggc gatagcttcc ttatcaaggg cagatccttc tgtcacataa
    30481 tatgagacat ccgcaatatg taccccaagt tcatagttac cgttatccaa tagcttaata
    30541 tggatagcat catctaagtc tttggcgtcc gcaccatcaa tagtaatggt ggtttcttga
    30601 cgcaaatcca cacggcctat taaatcttta gcagttggtg cttctgaaat agcattggcc
    30661 tcggctaaaa cttctgctgg gaactctgac acgatatcca tcgattcaag gacttctagg
    30721 acatcaattc caacgtctcc ttgatggcct acgatatcac gcacactggc tacaaaataa
    30781 tcgtgcccgc gtgtcgggta tttatcaata tcaaccttga tgatttcagt gcctttaagc
    30841 acaacaggtt cttttttgat atagattttt tgttgaatct tttgattttt ggacctgata
    30901 taaccagcat attttggttt gtcatcatct aaaataaagg ttccaacagc tgtttttaaa
    30961 gaacggtcaa caatagcaac gaccttagct tcagccgctg tgcctttgag acggtctgct
    31021 ggctttttaa ccactacttc gacagtatca ccatcaatag catacccaac atcattacga
    31081 ccgataaaca tgtcatcttc attctcatcc acatgtaaga aaccaaagcc tgctttattg
    31141 gcacgaaaaa caccctgaac agtaggttct tttttctttt cacgctcttt tctaagagcc
    31201 agactgccat catctgaaaa ccgtaacagg ctctgacttt ccattttgga aatggtttta
    31261 ataaggctgg gaaaatgctt agctccagcc atctccaagg ccgcagccaa gtcgttcaca
    31321 ttggacttgc catgctcctt gaggtaagtc attattcttt ctttcatcat acctaatttc
    31381 tatttctgtt ttgtttgttg gaggatatca atccgtttcg ctgataaaaa aatgagctag
    31441 actaactctg tcaagctcac tccttattta cttgataaaa tggcaagcac aagtgcaatc
    31501 gctagccaaa aaaatactag aactgctgtg aatcgttgca tgaatgcttc aaagccacga
    31561 gcttttgtac gttcaaacaa ggcttctgaa ccgctgctat caaaaacatt gctacttggg
    31621 tttttttgag gttgcataaa aatagcaatc acaagcaata ccgacagtac tagcaatatc
    31681 gtaagtagta agttgtacat gttatttcct ccactattgt catgaccatt ctaacacaat
    31741 tcttatcaag tttcaacatg cagggtcact tttctctcct tggggcagta tttgggaact
    31801 tttatttttt ccggatgact gcttttattt ttactggtta gataattgtt actgccacac
    31861 tcactgcatt ctaaattaat ttttactctc acacaatatc cttaacttta atatattttc
    31921 gaaatataat caaactccat attaaattaa caaacacaat caaactagtc acataaaaaa
    31981 cagaacggta gcctagcact acagccacat ttgatccgat aaaagggcca atgacttgac
    32041 caaggttact aaacatttga ttataggcaa atactctaga aataccttct tttggtgtta
    32101 acttagttag taaagagtta atacttggca tcaaagcgcc cacaccaaac ccataagcaa
    32161 agcgtagtac tcctaattga aaactggtct gcgctaaggc actgctaaaa tacatgataa
    32221 agctataaca caaagcggct aacaataacc gatgattgcc aaatcgatct cctaattttc
    32281 ctaagtaaga actgctaaat aagctagaaa accccatggc cgaaactacc aggcctgaag
    32341 taaacattaa gttgtgagtt tgaccaagat gacgaatata caatgataaa atgggggtca
    32401 ctgattgagc tgaaatttga ataatcatac tagtcacaaa caaaccaagc ataatctggg
    32461 gactttttac ctgttttaaa atgacttttg taggtatcat ctcaaagcgc ctaatcggct
    32521 taaactcttc tttaacataa acagctgtca ttaaagaaca taaaaataat atcacaccaa
    32581 ctaataagaa aacttgtcga attcctaata gctctgccaa aattccccct agtaaaggac
    32641 caattaaagc gcctgctgtc actcctgttg ctaatgtgcc taaagcataa cctgactcct
    32701 cttttggggc ttggctggca atcaaggcag tggcatttgg cacatagccc gcaaagacac
    32761 ctgttaataa tctcaaaatg agtaaccaaa acacattagg aataatagct aaaccaccca
    32821 ttgtaaatgt catgacaaaa cttgctcgca gcatcatagg ttttcggcca taacgatcag
    32881 ccaacttccc ccaaacagga gcaaataaag ctgaagcaag tgccgtcaca gcaaccgcca
    32941 gaccagcata gtattctact aattctgtcg gagtacctaa attttccaca tacagagcca
    33001 taaaaggcat aacaagtgaa aagcttgccc cagtaaagaa gttaccaagc caagccactt
    33061 ttagattttg ccgccagttc actgtcgtta ccgctttatc actaatagat catcatcttc
    33121 tttccatcgg gcctttgatt attataacac atttctgcca aaaacagtgt cccataatag
    33181 tgctaagtct catctgatag ccttcatcgt ttacgtaagc tacccagtaa acctctgacc
    33241 agttctcgcc caattgttct aaccgtcgta ctaataaacg catctgttgc tttttcgacg
    33301 actgttttgc ggggacgccc aacagaacgg cgattagctt ttttggtagc agcttgtgcc
    33361 ttgatggctt ctttagcttc tttttcgcgt tgtgctgtcg ctatcgcttc ttgggccagt
    33421 cggttgtctt ctaaaacctt agcagctaat ttttcataag cagaatcacg atcaatggac
    33481 tgactatatt tactggcaaa aggtgaggac tgcacaagct gctgactttc tatatctgac
    33541 aaaacagcaa agctactctt aggcggcatg atataggcac gttcaacgat ggatggttgt
    33601 cccttatcat tcaaaacaga aatcaaagct tcgccgactt ctagttctgt aatcaccctt
    33661 gccacatcta agtcaggatt ttgtcggaaa gtatccgcag cgacacgaac cgccttttgt
    33721 tctttcggtg tataggcacg taaggcatgc tgaatacgat ttccaagctg agccaaaacc
    33781 gtttctggca aatcaagcgg gttttgagtc acaaagaaaa tcccaactcc ctttgaacga
    33841 ataagtcgca caatctgttc aactttttcc aagaaaactt taggggcatc tttgaagagc
    33901 aagtgagctt catcaaaaaa gaaaaccatc ttaggtttgt ccaaatcccc aacttctggc
    33961 aataattcgt acaactcaga caagagccaa agtaagaagg ttgtgtaaag ggtaggagat
    34021 tgaaaaagct tagtcgctga caaaatgtta atggctccat aacccgaagc aacatctaat
    34081 tgcatcaaat cagccacatc taaagcaggc tctccaaaaa attggtgggc cccttcttgt
    34141 tctaatgtca agagacttct ttggatagcc ccgatagatt gcttggcgat attaccgtaa
    34201 tggctggagt agtctgaggc atggtcacca acttctttta agatagcctg caagtctttc
    34261 aaatcaatca aaagccaacc tttctcgtcg gcgattttaa agacgatgtt taagacacct
    34321 gtctgggtat cattaagatt caataaacgc gacaacatca tcggtcccat ttcagaaatt
    34381 gttgtccgta agggttgacc gttttgacca aaaacatccc acattcttac aggaaaggcc
    34441 tgaggctggt aatcacttac cccgattgtg gctaaacgcg cagccaattt atcagtcacc
    34501 tctcctgctt tagtaagatt agacaggtct cctttgatat ctgccaaaaa gactggcaca
    34561 ccagctaaac ttaattgctc tgctagcact tttaaggtca cagttttacc tgttccagtc
    34621 gctccagcaa tcaaaccgtg acgatttagc atccctaatt gtaaggctat cggttgactg
    34681 ccttttgcaa ttgtcattgt agtcataggc ttcctctttt ttgatgatca tacttgtcga
    34741 tatgtgttta cccataagtt aaggtgttta gaagtgtctc gctcttaata ctattataac
    34801 atataaccct tgatgcgcta atttaaaagg gaccagctag ttttagacag aaatagcttg
    34861 attttgacag ctatgatacg aatctctcag cttagctacc tcggattggc taatgacaac
    34921 aacgcagatt gtacttgctt tattaacgtt tccatgtctc cattattatc aatcactaga
    34981 ctggcatagg gctttttttc ctctattggt aactgactgg ctattcgctg tcttgctttt
    35041 cctttgtcta aacgatttct agccattaag cgctgcaatt gtgtctgagc atctacataa
    35101 accagccaaa tcgcatcaaa ccagtcttgg tagcccaatt ccattaaaag gggaatatcc
    35161 atgaaaaaaa tggcttggct ctgtgctaag tggtcacgct tagccgccaa ttcttcctta
    35221 atgatttgat tttgaatggc tgaggatgtt gccatattat ttgggtttga aaaaagcatt
    35281 tctgacagct ttgtgcgatc taactcacca tctgctttta aaatctgatt cccaaaagct
    35341 tctctaagag cctcgtaaag acgaccgcct ttttcttgca aatcatggac cacttgatcc
    35401 gcatcaatca cctgataacc agcttttcta atgaccttaa ccacagtcga ttttcctgat
    35461 gcaatgcctc ctgtgatgcc aataatcatg gtcttttttt ctggcatttt ggacaaatgt
    35521 gcgtccccct tcctccaact tttaatttga caatagcctg tccacaacga ggacacggtt
    35581 tcccagtttg accataaacc tgcaaatagt cctgcatggt gccatcagct cccaaagcat
    35641 tacggtaagt acggacggtc gaaccgccct tttcaattcc taaagctagg attcgtatgg
    35701 tttcatcatg cagccgtttt atctccgcct tattcaacct agaagacgca gtttctggat
    35761 gaaccttagc agcccaaagt acctcgtcta cataaatatt ccctaaacca gcaaccaagg
    35821 tctggtctaa cagatgtggt tttatgggtt tttgggagga tagcagagca gcctcaaagg
    35881 tttttaactt aaaggtctct ttctttggtt cagggcctag ttttcgtttg gcaaaaaatg
    35941 ctgataattg agattttgct atcaaatcaa aggttccaaa tttacgcaca tcttggtaaa
    36001 ccaaggtcga accatttttc aattcaaaaa agacatgaaa gtgtttgtta tcagggacct
    36061 catctggaaa aagcaaatat ttgccttcca tccgcaaatg tgataccaac actaattgcc
    36121 ccaaatcaat taataaatat tttccccgac ggccaactga ctgaatgatt tgaccaggta
    36181 gggtcagagc aaacgtctct aagtcggttt taaccatttt tggtacttta agcgtaacag
    36241 ccacaatttc ttggccaagc actaaagtct caagccctcg tcggaccgtt tcaacttctg
    36301 gtaattctgg cataatccgt tatttaaagg acagctagac cctttgctgc tacaaagaat
    36361 aaactcagta taaaaaagtc actcaataga ctcaggtcta ggctactgac tgcgtttcaa
    36421 aaaacacagc tgtccttctc ctttcttatt tcttatttta cgaacacatc tgatagaaag
    36481 caactcataa atctgcctca gaccagtcct catccccctt acctcccagc actatttgac
    36541 ggtaatgttc cttataacta taatacaatg agtcctctcc aagatactta aaaatctgca
    36601 aggcctgccg catgtcctct tctccagaca tttcttcctg ctttaattta taatacccat
    36661 gcacatataa gaaaacagtc ttttcataaa aattgagctc gtctcgcagc aaaagatcaa
    36721 ttttgttaat caaatagcga ctatgttcaa agcaagaatg gtcaatactg ataatgagac
    36781 aattaatgga taactgagtc actaacattt tattggtttt attttgttcc gaataagcaa
    36841 aagatgctac catttcctta gtcaataaaa atagggtatt gtaattcatg aagcgcgagc
    36901 aattccccag aagaatgatt tcataatatc cccactgttc cactttaaat aaataatctg
    36961 tgaggcgagt caattcttct tgactaggtg caattgagga gtcaatagaa aaaagaatag
    37021 ctttaatcat cgttcgttca taatctttat gggcataatc cttcaacagt ttggtcaatt
    37081 taaccacgtt tttctcagca taacattttc tcgcctgact taagagcgtg aaaaaatgcg
    37141 tatgcgtctt ggaatgagcc gaaacaaatt cgtcaatcgt aatattcagt ttatccaaaa
    37201 gattaagcaa gcgactgcag gtgatttctg attcccctcg ttcaaatctt gaaatttgtg
    37261 acttggacag gtattcatct gctaaaaaag aaatgctaac ctgcttaccc ttacgtaatc
    37321 gccttaaggt ttttccgagt tctttttcca tttttcccac tttcacaaca aaaaattaaa
    37381 atctgctaaa tccattatat aatacaagta caaaatagaa aatcagaaag gagacagtca
    37441 tgaaaaaagt taataaagct ttgcttttta cattgatcat ggatatcctg attatcgttg
    37501 gtggataacc tttcgcttaa aaacaatcca cttttgggaa acccttatat ttagtttgta
    37561 acaggaaaac taatagatat taaaaagagt gttagcgacc tagcggcagc tttactctta
    37621 agtgcgtttg ctgccattga cagcaaggtc aaagctgatg aaacagcagg ggcataccgt
    37681 tatgatgtgt ctaaacaaaa cacttactat caaactatca gctccattaa ccagcaacga
    37741 cctggtgcca ctctcgacga atgaggtgat tattatggaa cccttacttc atttacttcc
    37801 caaagtcgta ccagtactta tacacttggt agacaaagcc aacgtatcat ggttaacagt
    37861 gatattacag ttacctatac tcttaaagac aatttggtag cccttcataa ggaatataaa
    37921 acctttgtca aaaaaatatt acagataaac cgatcaccag tgactacgac aaggctaagg
    37981 ttatttataa ccatttaatc aacgaataca cttacgccac aaaataactt agcaccaatc
    38041 gcaaaaccgt aagcagcatc aacaatcata ctcctaaagc tctttatcgt ggcaagtgtg
    38101 gtgcttgtca agcttatgcc gtcatgttta aagatatggc agaagctgca ggcttatcaa
    38161 cttggtatgt gataaaaaag gattgaatga gcaccatact tgaaacatcg ttaccattca
    38221 tggtgttaat tcctacgttg atgctacctg gaatgattca gcatacacca caaggtattt
    38281 ccttgctgga aaagacgtga ggaatactga gtaccgttta gatagccagt acaaccactt
    38341 ggctaatact attttaaata ccagctacca aaaaggctaa actaacaaca actacatttt
    38401 tcaactagaa aggcctaaac aatgaccaaa aaacagtttt atcttatctt agctattagc
    38461 atactgtgtt ttattcttgc cgtcagccct aaaccaccaa ttcctaaaca cactattgaa
    38521 aggaaaagga ctacgatgac cataggccac tcaaaacaaa accctcacaa aaaagaagcc
    38581 cttaaacaca aaaaaaataa aaataaggct ctatttcttc caagtgggga cagcgctatc
    38641 aaatctgtta ttagcatgac agttagactc ctgttagatg accaatctta gctctcctaa
    38701 aatcagtgga cactaccatt tcggtagtgt tcttttttaa gctaatctca tcaccacgct
    38761 ttcttcaagc taaaaaactg atcatgaaag agcaacccca tcaccctaac agcccacttt
    38821 gcccgcactt tcttaaaaag ttaggagaaa acgatatacc aattattttc tgatcccagc
    38881 tccctatcat taacaagatg tgtagcacgg acctacatac aggtaagcta gagtcattct
    38941 cgctatttcg gacaaaaaga ggccggtagt tccctgacct cttctttatt tatcttgtaa
    39001 cactcctctt cttagcgaga cttactagca cataattctt aagcactctt atcatttaga
    39061 ctaggaataa caccatctga atgaagcaaa tgatgcgcca gatctgccag agtatcatct
    39121 ccataagtaa tccctgtttg gtgctgtttc tgatgaaaat cagatgactc cttaacttta
    39181 gcagtcacct gctggtcact tggatgaaaa ttaatttctc tcttggcttc agccgcaact
    39241 ggctcgagga acaacttatt gacattacgg tcttcctcca aatgattaag gatagcagca
    39301 tcatcttcta acgaaagaac cttcttgggt aacaaaaagg ggttatttag ccttggctca
    39361 gtaacgactt ccttggctgc tcgtgatagt ttattattgt cttcctcagg tatcaaacga
    39421 ttaagcaatc gatgcaattc ttccggctat gaggcgctca cagctacttc agaagaaacc
    39481 tccaagccct ttcctgtttg cctgtctaaa gcaaccggca aattattaac taacttttta
    39541 acctgtcctc agcgctcatt tcaacactag gaagagctgt cgctggttct agccagctac
    39601 caacttctgc tggtcttacc ttaacatcgc tggcaggctt ctccttctca tcttcattag
    39661 gtctaaaagg ctcaaaccgc cctgttgatt tttcatctat gacctttata ttgtctttta
    39721 ctacatgaga cagtggttcg acatttacca tagcttcatg ctcgttaagg ctctggtctc
    39781 gtttgaattt accaggaata ccaggagtcg gtgttccaac agattgatcg gcttcagtag
    39841 gctcttttac ggagcctttt ttccataaaa ctgctggagg aataatatcc gtagagccat
    39901 ccccataagt aatcgtggcc tgcctcccct ttggattaat agatacttta atattgtctg
    39961 ggaaagcccc actacctcct gtggttaaaa gggcacccgc atttttaatg agagttgtca
    40021 ttcgttcaat accagcaacg ccaatatggt tcaagtcatc tactggtaac tgatcaacag
    40081 atttcatggt gtatttccaa gcttgcggtt gaacaagaaa aacagttcct ttatacattg
    40141 tgttatgcat atcatcaatg actttgaaat accttgtata tttggtttgt acattagggt
    40201 tagcaacggg aacagtgctt tcaggaactc ctgacatcgt aaaaatccct ctagcagaag
    40261 tttgaaagcc ctcataaaca tgacccatac caggaacagt ctgagcggtc aaagacttac
    40321 cagaaccatc caaagcaatg cgaatatctt tcatcagata catctgattg gtataggtaa
    40381 acctaaccgt gttagcctca cctcgataca aaaccacttg ggagggctga tccgaagaaa
    40441 actgagaggt tgtttcttcc ttatagccaa ctccaaaacg tctatcagac gaatggactg
    40501 aatctgccgc aactgtacta ctcaaactga ctagtaaagt agccgcacaa ccaactaata
    40561 aactgctcgt tttaacttta acatctctta acatcatcat gttcctttca ttatttttta
    40621 tttaggaatt cgtcatacta tattttctca tattagtcta acaaaaaact cgtaattcta
    40681 tataaatcat ataaaatgac gagctttggc aaagatgagt atagcaggat ggaaaacaga
    40741 ttgtttctga aacttcaaag gtatcttctt gtcacgaact attctttaat tgaatcggtt
    40801 ac
//
LOCUS       DAUGUF010000016        40789 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUGUF010000016 DAUGUF010000000
VERSION     DAUGUF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40789
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.016"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            473..949
                     /locus_tag="VIB71_000833"
     CDS             473..949
                     /locus_tag="VIB71_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEQ8822582.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            1007..2188
                     /locus_tag="VIB71_000834"
     CDS             1007..2188
                     /locus_tag="VIB71_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8822583.1"
                     /translation="MPLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            2178..3425
                     /locus_tag="VIB71_000835"
     CDS             2178..3425
                     /locus_tag="VIB71_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEQ8822584.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVSISPEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLLYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(3484..5136)
                     /gene="fbp54"
                     /locus_tag="VIB71_000836"
     CDS             complement(3484..5136)
                     /gene="fbp54"
                     /locus_tag="VIB71_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEQ8822585.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFEPVLFSDSHATFETLSEMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            5490..6488
                     /locus_tag="VIB71_000837"
     CDS             5490..6488
                     /locus_tag="VIB71_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8822586.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANRQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAATSKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            6833..7702
                     /locus_tag="VIB71_000838"
     CDS             6833..7702
                     /locus_tag="VIB71_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822587.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERYFKGVRLTR"
     gene            7699..8457
                     /locus_tag="VIB71_000839"
     CDS             7699..8457
                     /locus_tag="VIB71_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822588.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            8661..10322
                     /locus_tag="VIB71_000840"
     CDS             8661..10322
                     /locus_tag="VIB71_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ8822589.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            10455..11240
                     /locus_tag="VIB71_000841"
     CDS             10455..11240
                     /locus_tag="VIB71_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEQ8822590.1"
                     /translation="MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGK
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            11270..11596
                     /locus_tag="VIB71_000842"
     CDS             11270..11596
                     /locus_tag="VIB71_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822591.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            11642..13549
                     /locus_tag="VIB71_000843"
     CDS             11642..13549
                     /locus_tag="VIB71_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8822592.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDKTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQETLME
                     EWETIAEQIES"
     gene            13836..14804
                     /locus_tag="VIB71_000844"
     CDS             13836..14804
                     /locus_tag="VIB71_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEQ8822593.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            14863..15861
                     /locus_tag="VIB71_000845"
     CDS             14863..15861
                     /locus_tag="VIB71_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEQ8822594.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            16046..17455
                     /locus_tag="VIB71_000846"
     CDS             16046..17455
                     /locus_tag="VIB71_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEQ8822595.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPTVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIKAILEVAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            17782..19545
                     /gene="lpdA"
                     /locus_tag="VIB71_000847"
     CDS             17782..19545
                     /gene="lpdA"
                     /locus_tag="VIB71_000847"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEQ8822596.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAI
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            19854..19931
                     /locus_tag="VIB71_000848"
                     /pseudo
     CDS             19854..19931
                     /locus_tag="VIB71_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(20219..22636)
                     /gene="hylA"
                     /locus_tag="VIB71_000849"
     CDS             complement(20219..22636)
                     /gene="hylA"
                     /locus_tag="VIB71_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEQ8822597.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYVKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASTNITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLNRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEASSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTSVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            22869..23858
                     /locus_tag="VIB71_000850"
     CDS             22869..23858
                     /locus_tag="VIB71_000850"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8822598.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILTKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            complement(23967..24758)
                     /locus_tag="VIB71_000851"
     CDS             complement(23967..24758)
                     /locus_tag="VIB71_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEQ8822599.1"
                     /translation="MTYTSLKSPENTDYLYNLNIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGARVTVDIVSLNDAFDQDYYDLVFFGGGQDYEQTIVAKDLPSKKAALADYIAKNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLYDDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKEKYGSAITLPSYDDILKQEVAEEYADIKRKAAFDKA"
     gene            complement(24758..26101)
                     /locus_tag="VIB71_000852"
     CDS             complement(24758..26101)
                     /locus_tag="VIB71_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEQ8822600.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGQLALACNKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     GRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFICLNCGFKRPQLDYRLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIMEAIEKQESKHAYILATYTAMLEFRSLLADRHVVEKEMN"
     gene            26208..27059
                     /locus_tag="VIB71_000853"
     CDS             26208..27059
                     /locus_tag="VIB71_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEQ8822601.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            27056..28012
                     /locus_tag="VIB71_000854"
     CDS             27056..28012
                     /locus_tag="VIB71_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEQ8822602.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            28066..29421
                     /locus_tag="VIB71_000855"
     CDS             28066..29421
                     /locus_tag="VIB71_000855"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEQ8822603.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIIFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            29545..30186
                     /locus_tag="VIB71_000856"
     CDS             29545..30186
                     /locus_tag="VIB71_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822604.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLTD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            30249..31379
                     /locus_tag="VIB71_000857"
     CDS             30249..31379
                     /locus_tag="VIB71_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEQ8822605.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FESYDIHDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLEQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            31389..32141
                     /locus_tag="VIB71_000858"
     CDS             31389..32141
                     /locus_tag="VIB71_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEQ8822606.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQIISDGQLNAQAMIEWRAIKQTESEID"
     gene            32141..32905
                     /locus_tag="VIB71_000859"
     CDS             32141..32905
                     /locus_tag="VIB71_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEQ8822607.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQSMLAKQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYIEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            32905..33537
                     /locus_tag="VIB71_000860"
     CDS             32905..33537
                     /locus_tag="VIB71_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEQ8822608.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            33982..38088
                     /gene="cas9"
                     /locus_tag="VIB71_000861"
     CDS             33982..38088
                     /gene="cas9"
                     /locus_tag="VIB71_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEQ8822609.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGEIAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSK
                     SRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRLNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKE
                     HPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMLAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PTAFKYFDTTIDRKRYTSTKEVLDATFIHQSITGLYETRIDLSQLGGD"
     gene            38088..38957
                     /gene="cas1"
                     /locus_tag="VIB71_000862"
     CDS             38088..38957
                     /gene="cas1"
                     /locus_tag="VIB71_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ8822610.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKA
                     LNNEGKGVPEFRI"
     gene            38954..39295
                     /gene="cas2"
                     /locus_tag="VIB71_000863"
     CDS             38954..39295
                     /gene="cas2"
                     /locus_tag="VIB71_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ8822611.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            39285..39947
                     /gene="csn2"
                     /locus_tag="VIB71_000864"
     CDS             39285..39947
                     /gene="csn2"
                     /locus_tag="VIB71_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEQ8822612.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSEL
                     KFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
     gene            40331..40789
                     /locus_tag="VIB71_000865"
                     /pseudo
     CDS             40331..40789
                     /locus_tag="VIB71_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
BASE COUNT        12821 a         6919 c         8503 g        12546 t
ORIGIN      
        1 attgggaggt tgtgacaatc gagcggatat cagatgttat ggcagaactt tctgagtctg
       61 aataatttta gttcatcaaa gaatcaagaa agaaccattg gggcaaaatt ggggcataag
      121 tttagaactt ttgtcgtttc ttgtgtcgat acaataccgg tttaatacta acaaatgctt
      181 ttattatcga ctttgtaacc attattgttc cttgtgtttt ttcgggaata aactcaagaa
      241 gtgattaaat aaaacattaa agaaccttgt catatcaatt atcgttgata tgacaaggtt
      301 cttttgatag tttaaattga tgtttttcat tgtaggctct tatctacact tttttaaggc
      361 atctttagaa ggttttgagc gtgactaagt attcacactt tgactcataa aatgatagca
      421 tattttctag agattggtat aatagaaaca aagatggaaa ggaaagagat agatgactca
      481 attagcaacc atttgttaca ttgataatgg cgattctttg ctattattac accgcaataa
      541 aaaagaaaat gatgtccaca aaggcaagtg gatttcagtt gggggtaagc tcgaggctgg
      601 tgagacccca gatgagtgtg cccgtcgtga gattttagag gaaacccatt tgactgttac
      661 agagatggcc tttaaaggaa tcattacttt tccagaattt acccctggtc atgactggta
      721 tacctatgtt tttaaagtaa caggatttga aggagacctc atttcagatg aagagtcacg
      781 agaaggaacc ttggaatggg taccttacga tcaagtgttg gaaaagccaa cttgggaagg
      841 tgattatgac atttttaaat ggattttaga agaccgtcct tttttctctg ccaaatttac
      901 ctatgaccaa aacaaccaac tcatggataa atctgtgacc ttttattgat ttacccaggt
      961 taccagtaaa acttatcatt ttcccaaaga aaggaaccct atcttaatgc ccttaatacc
     1021 tgaaaagtct agaacagata gcttatttta caaatggttt ttaaataatc aagctaccat
     1081 ggctttagta ataacacttt tagccttttt aacgattttt gtttttacta aaatctcttt
     1141 tttatttatg ccagtgattt ctttttttgc ggtcatcatg ttgcccttgg ttatttcgac
     1201 cattctgtat tatctgacca aacccttagt tgaccttatt aatcatttgg gcccgaatcg
     1261 taccacctct atttttattg tttttggttt gattacctta ctttttgtct gggcgatttc
     1321 aggctttgtt cccatggtac agacccaact taccagtttt attgaggatt tgcccaaata
     1381 tgtgggcaag gtcaatgaag aagccaataa acttcttgaa aatgaatggt tagtcagcta
     1441 caagccccaa ctccaagaca tgcttaccca tacaagtcaa aaggctttgg attacgcgca
     1501 aagtttttca aaaaatgcta ttgactgggc tggtaatttt gctggtgcca ttgctcggat
     1561 taccgtggct attattattt cgccctttat tctcttttat tttttacgag acagtagcca
     1621 catgaaaaat ggccttgtga atgtcttacc tctcaaatta cgggtgccta tggttcgagt
     1681 cttgggagat attaacaagc aattatcagg ctatgtccaa gggcaggtta cggttgcaat
     1741 tgttgtcggc tttatgtttt ctatcatgtt tagccttgtg ggactgaaat atgccatcac
     1801 ttttgggatt attgctggct ttcttaacat gataccttac ttaggaagtt tccttgccat
     1861 gatacctgtt gtgattatgg ctatggtaca aggcccattt atgttggtta aggtgcttgt
     1921 tatctttatg attgagcaaa ccatcgaagg ccgttttgtg gcaccgcttg ttcttggaaa
     1981 taagctgagc attcatccga ttacgatcat gttcttattg ttgactgcag gatcaatgtt
     2041 tggcgtttgg ggtgtcttct tagtcatccc aatctacgct tctgtcaaag ttgtgattaa
     2101 agaattattt gactggtaca aaaaagttag cggtttgtat gacgaagaag tattggtgat
     2161 tgaggaggtt aaggaccatg ttaaatagtg aaaaaatgat tgcttccttg gatcagcaag
     2221 acctagcgca cgctgaaaaa tatttccaaa aagctttaaa agaagatgat gcagatagtt
     2281 taatcgcctt aggagaatac ttagaaagta taggtttttt gccacatgcc aagcgtattt
     2341 atttgcagtt agctgatgat tacccagaac tcaatataaa tttagctcag attgcagcag
     2401 aagacgacgc cattgaagaa gctttcttgt atttggataa ggtttcaaaa gatagcccca
     2461 attatttgtc agctctctta gtaatggctg acctctatga catggaagga ctgacagagg
     2521 tggcgcgtga aaaattgctt caagcagtga gcatcagccc agagccattg gtcatttttg
     2581 gtttggcaga aattgacatg tccttgcagt attttaaaga agctattgat tactatgcac
     2641 agttagacaa tcgtcaaatc cttgaattga caggtatttc cacttatcaa cgcattggac
     2701 gagcctatgc tagcttaggg aaatttgagg cagccatcga attcttggaa aaggccgtgg
     2761 ccattgaata cgaagatgaa actgtttttg aattggcgac cctcttgtat gaccaagaaa
     2821 attatcaaaa agctaatctt tactttaaac agttggaaac catcaatcca gattatccag
     2881 gttatgaata tggttatgct ttgagtcttc atgaagagca taagacgtca gaagctttgc
     2941 gcttggttca acagggccta cgtaaaaatg catttgacag tcaattatta ttactagcat
     3001 cgcagctttc ttatgaatta cacgataggc agaatgctga aaattacctg cttcaagcaa
     3061 aggaagtagc tgttgatgac gaagagattc tcatgcgttt agtgaccctt tattttgatg
     3121 ccgagcgttt tgaggaggtt attgctctta atcgtgagac gattgataat gtcttaacca
     3181 aatggaccat tgcaaaggct taccacgcct tggaacaaga agaagttgcc ttggctcttt
     3241 ataatgagat ttcggctgat ttggcagaaa atccggagtt tttacaggat tatgcctatt
     3301 tattaaggga gtttggccag tttcacaagg ctatccaaat ggctaccgct tacctcagac
     3361 aagtgcctga tgatgtgaat atgcaagact ttcttgacca tatcaagcac caacaatcag
     3421 aataaaaaaa cagttctcct aggggaaata actttcctag gagagctgtt ttttagttgc
     3481 ttatcaggat aatttcatag agagaatttt ggcttggtca ggagtaaccc gtaaagtttt
     3541 ttgaccagta taagtcacaa atcctggctt ggcgccacta ggtttgtgta attttttagc
     3601 ttcaatcata tcgacctgaa cgagatttga taacctagct ttcgaataat aagcagctag
     3661 ttcggcagca tcagttttaa cctcgtcact tgggtcaaga ttgtctttga tgatgacatg
     3721 acttccaggg atatccttag catggaacca gagttctcct tttttagcca ttttaaaggt
     3781 gagttcttca ttttgcaagt tattgcgtcc caccatgaga atggtttttc catctgaagc
     3841 caggtactgc tcaggctttt tacgtttatg gcgtttgtct ctttggcgac ttttcaaaaa
     3901 gccagcctga tataattctt cgcgaatatc ttcgatgtcg tcgatacttg cttgagataa
     3961 attgtagtcc acgctctcaa agtaagtaat actttgcttg gtatcggcaa tcaaaccaga
     4021 taagtgtttg acagcttctt ttagcttttg gtatttttta aaataacgtt gagcattttg
     4081 atttggtgtc agagccttgt ctaaggcaat ctcaattttt tcccctgtat aataattgtc
     4141 taaaatcaca gagtcttggt tgtttgggac cagactgagg taggtggtca ataattctcc
     4201 tttttgacgg aataattcag cattttcagt ggctagcagc tcagcttctt gcttacttag
     4261 cttgttacga tttttgtcca gttcagtttg cacacggtga atcaaatcac tggcttgctg
     4321 attgatacgg tcacgctcag ccttatcttg ataaaagtga tcaagcatct ctgataaagt
     4381 ctcaaacgtc gcatggctat ctgagaaaag aacaggctca aaagaagctg tggtcagatt
     4441 tgcctgagta ggtctagcaa aaaactcacg gaaccgtttt aatttgtctg tggtcagaag
     4501 ctcggccaac tcttttgcgg tgtctcgccc caaaccttga aaatgctgtt gcaagctttt
     4561 aactgttagt tcttgtgttt ggaggatttc aaatagagga acatctgtaa ttgtaaaagg
     4621 attaacagca gctgttttag ggggctcaat gtaggtagag ccaggtaaaa tggtgcggta
     4681 agagttttgt gaaaagccaa catgtttaat ggattcgatg attttatttt ctgcacggtc
     4741 caccaagatg atattgctgt gcttccccat gatttcaatg attagggttg cctgaatagc
     4801 atctccgatt tcatttttat tagatacctt gatttcgata atgcggtcat tatcaatctg
     4861 ttctaactgc tcaatgactg caccctggag gtatttacgc ataatcatgg taaaggtatt
     4921 aggtacctga ggattttgaa agtctgcttg ggtgatttgt acccttccaa aaacaggatg
     4981 ggcagacaat agcaatttat aattcttgcg atggttacga atggttaaga caagttcccg
     5041 ttcaaagggt tgattgacct tttggatacg accgtaaagc aagttctctt ttaattcgtt
     5101 ggttaaatgg tgtaagaaaa agccgtcaaa agacatggtt tctcctttct gaattctaat
     5161 ctcttcatta taccacaaat acttgactaa aaatatggac gaaagagctt gcaatttttt
     5221 tgatttaggt tataatgtta aaaaaacgag aaaggaagtc aatgatggta aaaacacaac
     5281 acttagtaaa ttggcaaggc tggcatagat aagttgtgtt tatgaattgg catagatacg
     5341 acttttagag tacttctaaa aagatatcta tgcgctgaca ttggatttca caagggcgcc
     5401 tagtaatcat tactaagtgc tttttctttt gagaagtatt ctcatcatca acgttttaaa
     5461 gagattgaca tgaaatgtga ggaattcaga tgaaaaacaa gagtttaata gctaccctcc
     5521 ttgttttaac tgtaatagtg ataggctctc tattatcaaa aggagtatca aaggaaaacc
     5581 gtgatttggc taaccgacaa aacattacaa ttggtatctt acaattcgtt actcatgagg
     5641 ctcttgatga tattaagcga ggtattgaag atcaactcaa aaagcagatg cctcaaaaac
     5701 aaaatgtagt gattaaggtt atgaatgctg agggggatca gagtaaaatc caaacaatga
     5761 gtaggcaatt agtgcaatca ggaagtgata tcgtgattgg tatcgcaacc ccggcggcgc
     5821 aaggcttagc agccaccagc aaggatatcc cagttgtcat gtcagcagta tctgatccag
     5881 taggatctag attagtgatg caattggatc aacctgaagc taatgtaact ggtctatcta
     5941 ataaagtgcc tgttaaacag acaattgatt taatgaaaaa gctgacacca catgtcaaaa
     6001 cagttggaat tttatatgca agtaatgagg ataattcctt atctcaagtt aaagagttta
     6061 ggcggttagc tcgcaaaaag ggctatcaag tcatttcata cgcggttcct tctactaacg
     6121 aagttcctgc cacgatgtca gttatgttag gtaaagtaga cgcggtattt atcccccaag
     6181 acaatactat agcaagtgca ttttcatcag tcatgacaac cagtaaggct gcaaagattc
     6241 ctgtctacac tagcgttgat cgaatggttg aaaaaggtgg tttagcagct atttctcaaa
     6301 atcagtacga tttgggagtt caaacagcta atcaggtgtt aaaattaatc aaaggaaagc
     6361 gtgttgtaga tgttcctgtc aaagttgtgg atattggtca accgctaatt aataagaatg
     6421 tagcagcaga attaggtatt gctattaaca gggaagattt tccttcagct tcttttattg
     6481 agaattaata caatgacatg tgatataaaa ggtcaagaaa aaaccataaa aaacaccctc
     6541 actgagatga atttggatgc caagtcagac aatcgtcttg aggatgtaag ggttattttt
     6601 atcattttta gttttaaaat gctctatttc agacacgtaa aaaatcttgc cttttgagta
     6661 agtttaaaca tgattctcga tttttttgtt ttctgtctta gtttcgttaa agtgattgga
     6721 aaaaagacta agccacggtg ctgaactaag tataaaacaa atctaaaaat taatgtaaag
     6781 aaagggttta tactggcgag agttacccgc taatataaat atgaggaaaa atatgattat
     6841 ttcatcagtt tcacaaggcc ttatatgggg agttttagga ttaggaatct acctgacctt
     6901 taggatttta aacttccctg acatgactac agaaggttct tttcctttag gaggagctgt
     6961 tgcggtcacc gctattagct tagggtggaa tccatttcta tcaaccttac ttggtatgtt
     7021 atcaggtgct ttagcaggtt ttttaacagg gctgttatat acgaaaggaa aaatgccaac
     7081 acttttagct ggaattttgg tgatgacgtc atgtaactcc attatgctaa tggtaatggg
     7141 aagagcaaac ttgggtttac atgatcataa acgtattcag gattgtttac ctttttcaat
     7201 tgatttaaat agccttttaa caggtctgat aactgttgtg attgttatta gcgttttgat
     7261 ctatttcctt tacactaatc taggtcaagc ttatatcgct acgggagaca ataaagatat
     7321 ggctaagagt tttggtatta acacggattg gatggaagtt atgggacttg tggtttctaa
     7381 tagtttaata gctttatcag gtgctctagt gagccaacaa gatggctatg cagatgtctc
     7441 aaaagggatt ggagttattg ttattggttt ggcgagcata attgttggtg aagtactata
     7501 ctcaactgga ctgactcttt tagaacgttt gattgctatt gtaataggct cgattcttta
     7561 tcaattttta atttcagtag ttattacgct aggttttaat acaagttatt tgaaattaat
     7621 tagtgctctt gttttagcac tgtgcctcat gataccagtg gtaaaagagc gctactttaa
     7681 gggagtgagg ttaacacgat gacaaaaatt attgaattga tcaatgcaac agttgacgta
     7741 gataatggtt ttgaagatgc taaaacaata ttggacaatg tgacactaac tatctatgaa
     7801 catgattttt taactatttt aggaggaaat ggagctggaa aatcaaccct ttttaatgta
     7861 attgcaggaa cgctaagttt gacacggggg caaattagga ttcttggtca ggatgtgacg
     7921 cattggccgg cagaaaaaag agctctttac ctatcgcgag tctttcaaga tcccaaaatg
     7981 ggaacagccc ctcggatgac agtggctgaa aatctcttaa tcgcacgtca aagaggagaa
     8041 aaacgctcct tggcttctcg aaaaataaca gagcacttag ctagttttga ggatttggtt
     8101 aaacgaacag gaaatggcct agaaaagcat ttagaaacac cagcaggtct tttgtctggt
     8161 ggacaaagac aggctttaag tttattaatg gcaacgttga aaaagccagc tctcttatta
     8221 ttagatgaac atacggctgc ccttgaccct aagacgagtc aatctttaat gcaattgaca
     8281 gatgagtttg tgacaaaaga tggcttaaca gctttgatga ttacccacca tatggaagat
     8341 gcattaactt atgggaatcg tctgattgta atgaaagatg gaaacattat taaagattta
     8401 aatcaaatgg aaaaagaaca actgacgatt actgactatt accaactatt tgattaatca
     8461 acgatctaaa tcattgacga ataataagtc agtgattttt tgatttccgt actgaaaata
     8521 atctgaaagt atcaaggcta tttagagaaa aaacgcctca aatatgatat actatagaag
     8581 atagtagcat agctacataa cagtaattcg acttacgttg taaggaccgt ttgtaataat
     8641 aaaatattta aaggagtatc atgactgata ttaaaatgat tgccttggga ggggtccgtg
     8701 aatacggaaa aaacttctat ttggtagaaa ttaacgattc tatgtttatt ttagacgcag
     8761 ggctcaagta ccccgaaaat gagcaacttg gggtagattt agtcatcccc aatttagatt
     8821 atgtaattga aaacaaaggt aaagtacaag ggattttctt gagtcatggc catgctgacg
     8881 ccatcggagc ccttccttat ttgttagctg aagtatcagc tcctgtattt ggatctgaat
     8941 tgactattga attagccaag ctatttgtga aaagtaataa cagcactaag aaatttaata
     9001 attttcatgt ggtagacagt gatactgaaa ttgaatttaa agatggccta gtttcgttct
     9061 ttagaacaac gcattcaatc ccagaaagta tgggtattgt tattggaaca gataaaggaa
     9121 acattgttta taccggtgac ttcaaatttg atcaagcagc aagagaaggt tatcagacgg
     9181 atttgctacg tttagctgag attgggaaag aaggggttct agctctttta tcagattcag
     9241 tcaatgcgac aagcaacgat cagattgcca gcgaatctga agttggtgaa gaaatggaca
     9301 gtgttatctc tgatgctgat ggccgtgtca ttgtagctgc agtagcctca aatcttgttc
     9361 ggattcagca agtatttgat tccgccactg cccatgggcg tcgtgttgtt ttaaccggaa
     9421 cagatgcaga aaatattgtc agaacagctt tacgtctaga aaaattaatg attacggatg
     9481 agcgtctttt aattaaacct aaggatatgt ctaaattcga agaccatgaa ttaatcatcc
     9541 ttgaagctgg tcgtatgggt gagccaatta atagcttaca aaaaatggca gcgggacgtc
     9601 accgttatgt tcaaatcaaa gaaggagacc ttgtttatat tgtaactaca ccaagtacgg
     9661 ctaaagaagc tatggtggcg cgtgtagaaa acttgattta caaggccggt ggttctgtta
     9721 aattaatcac tcaaaactta cgcgtgtcag gccatgctaa tgggcgtgat ttgcaactat
     9781 tgatgaattt gttaaaaccc cagtatcttt ttccagtgca aggagaatat cgtgatttag
     9841 ctgcccatgc aaagctagct gaagaagttg gtatttttcc agagaatatt catattctga
     9901 agcgtggcga tatcatggtg cttaatgacg aaggttttct ccatgaagga ggtgtacctg
     9961 ccagtgatgt catgattgac ggtaatgcta tcggtgatgt gggtaatatc gttttacgag
    10021 accgtaaagt cttgtcagaa gatggtattt tcattgttgc tattactgtt tctaaaaaag
    10081 aaaaacgcat tatttctaag gctaaagtta atacgcgtgg atttgtgtat gtcaagaaaa
    10141 gtcatgatat tttaagagaa agtgcagaat tagttaatac aactgttggc aattacttaa
    10201 aaaaagatac ctttgactgg ggcgaattaa aagggaatgt cagagatgat ttgtctaaat
    10261 tcttatttga acaaaccaaa aggcgcccag cgattctgcc ggttgtgatg gaagttcgtt
    10321 agtgaaaata ggaaggttag gcaaaaactg cctaccttct ttgattttaa caactggtaa
    10381 accaggaaac tgttcaccca aaaatacagt agatttacgt gataggatta ttttggtata
    10441 aaggagtgta atgaatggca agtattgcaa ttgaatacca ttcggtagtt ttaggaatgg
    10501 agcgtaaggt aaatgtgatt tatcctgacc agtctgaaat ccctaaaaaa gatcaagggg
    10561 ataaggatat tcctgtttta tatttgttac atggtatggg aggcaatgaa aactcttggc
    10621 aaaaacgaac agctattgaa cgcttgttgc ggcataccaa tttgatagtc gttatgcctt
    10681 cgacagacct aggttggtat acagacacgg cttatggact taactattat cgggcgttgt
    10741 cacaagagtt accgcaggtc ttagcagctt tctttcctaa tatgacccag aaacgagaaa
    10801 aaacctttgt tgctgggctc tctatgggtg gttatggtgc ctttaagtgg gcactcaaaa
    10861 gcaatcggtt ttcttatgcg gcatcgtttt caggtgcttt ggatttttct cctgagacct
    10921 tgcttgaggg aaaactggga gaattagcct attggcaggg cgtttttggc cagtttgatg
    10981 accctgacct tgacaagcat taccttaaaa atatggtggc agaaagtgat ggaaaaacca
    11041 aattttatgc ttggtgtggc tatgaggatt ttctttttgc cactaatgaa aaagctattg
    11101 ctgattttca ggctcaaggt cttgacattg attatcataa aggtcatggt aaacatgagt
    11161 ggtactattg gaaccaacaa ttagaagttc tgttagagtg gttaccgata aactaccaaa
    11221 aagaagaaag gttatcttaa ccatttccta gtacaacatg aggtgacaaa tgaaacaatt
    11281 actggcgatc attttgtggc tgcctaagct aatagtgaaa atgttttggc atcttatcaa
    11341 agggttttta caaactatct tattagtaac gattattatt atagggctga tgtactattc
    11401 taatcacagt gattccgttt tagccaataa gatctcgata gttactgagc aagtggtgca
    11461 aatttttgat atcttaacac aaaagccatc tgcaaagacg cgtcatggga gtggtaatag
    11521 tcattccact ttccttgtta gcgctaaaga aggtaatcaa cgacttaaaa agagttcgat
    11581 ttcttttgga aactaggctg aaaatgtcct caaaagggca tttttttgtt agaatgaaag
    11641 tatgattatt ttacaaggaa acaagttaga acgctctttc tcaggagatg ttctttttca
    11701 aaacatatca ctgcaagttg atgaaagaga cagaattgca ttagtggggc caaatggagc
    11761 tggtaagtca accttactca agctattggt tggggaagaa accccaacga gcggagaagt
    11821 taatactaaa aaagacctaa ccttgtctta tctggctcaa aatagccgtt ttgaatctga
    11881 caaaacgata tatgaggaaa tgctcaaggt tttcgaagca ttacgacagg atgaaaagcg
    11941 cctgcgtcag atggaaatgg atatggcaac cgtttcaggt caagatttaa cccgactgat
    12001 gacagattat gatctgctta cagagcattt tcgtcagcaa ggcggcttta cgtatgaatc
    12061 tgacatcaaa gccattttaa atgggtttaa gtttgatgag agcatgtggc agatgactat
    12121 cgctgagctg tcaggaggtc aaaacactcg tctggccttg gctaaaatgc ttttagaaaa
    12181 gccagaacta ttggtccttg atgagccaac aaaccactta gatattgaaa ccattgcctg
    12241 gttagagaac tacttggcca attatcaagg agctctaatc attgtgagtc acgaccgtta
    12301 ttttttggat aaggtggcaa cagtgacctt ggatttaact cctcatggat tggatcgcta
    12361 cgttggcaat tattctcgtt ttatgacttt aaaagctgaa aaattagtag ccgaagaaaa
    12421 gcagtttgac aaacagcaaa aagaaattgc caagttagaa gattttgttc aaaaaaatat
    12481 tgtcagggct tcaactacaa aacgtgctca ggcgagacgt aagcaattgg aaaaaataga
    12541 acgcttagac aaaccgacta gtgctagaaa atcagctcac atgacttttc aggcagataa
    12601 gccgtctggc aatgtggtgt tgacggttga aaaagctgct attggttata accaacatgt
    12661 tttatctgag cctattaacc tagacgttca caaattagat gcgattgcta ttgttggtcc
    12721 aaatggtatt ggtaaatcca ctctgattaa atctgttatt ggacagattc ctttcatcaa
    12781 aggagaagtg aaatacggtg ccaatgttga aataggttac tatgaccaaa cccaatcaca
    12841 tttgacgtct agcaacacag ttttggaaga attatggcag gatttttcaa ctacgccaga
    12901 agtcgatatc agaaaccgat taggggcttt tctcttttct ggagatgatg tcaaaaaatc
    12961 ggtggccatg ctgtcaggtg gagaaaaagc ccgtctgctt cttgcgaagt tatctatgga
    13021 aaacaataat tttcttgttc tggatgagcc gactaaccac ctagacattg acagtaaaga
    13081 agtgctagag aatgccctca ttgactttga cggcaccttg ctttttgtca gccacgaccg
    13141 ctatttcatt aatcgtttgg caactaaggt tctggaaatt accgaaaatg gctcaaccct
    13201 ttacttaggt gactatgatt attaccttga gaaaaaggca gagctagaag aactagcccg
    13261 cctagcagca ggagagacag ttgaggaaac aaaagaagcc tctgccactg attatcagct
    13321 acaaaaagct aatcaaaaag agcgtcgtcg cttgacccgc cgatatgagg agattgaagc
    13381 aagacttgaa accattgaag agcgcattgg tgctattcaa gaagacatgc atgcctccaa
    13441 tgatacggcg cagttaatcg cttggcaaaa ggaatgggac caattggatc aagaacaaga
    13501 aactcttatg gaagaatggg aaaccatcgc tgaacaaata gaatcataaa aataagcttt
    13561 agcagttttg ctaagcttat ttttatcgct ttgttacttg tttgaaggtg tgaaagaggt
    13621 tttaaaatga tgtgtttttt ttatgtcaag gtcggtaaaa cgtgaaactg ttatatagta
    13681 tttttaaatt ttttagtaca gttttgtttg taatttcaca aactattgca tttctaaaaa
    13741 accaaataag gtaaggtaga aagcgattta attatttgca aattgtgaaa aaaagtttta
    13801 tcataaaaag gtaatatgat aatatggagg ccgaaatggt aacagtttct aaagaacaac
    13861 atttggatat gttccttaaa atggaacgta ttcgtgaatt tgattcacgt attaataaac
    13921 tcgtccgtcg tggatttgta caaggcatga ctcacttctc agttggtgaa gaagcagcca
    13981 atgttggagc ggtggctcac ttgtcttacg atgacattat tttttcaaat caccgtggac
    14041 atggacaatc aatcgctaaa gacatggacc ttaataaaat gatggctgag cttgctggta
    14101 aagcaactgg tgtttctaaa gggcgtggtg gctcaatgca cttggctgat tttgaaaaag
    14161 gaaactatgg taccaatggt atcgttggtg gtggttacgc tcttgcagtt ggtgctgccc
    14221 tcacccaaca atacaaagga actaacaata tagctgttgc tttctcaggt gatggcgcta
    14281 ctaacgaagg atcattccac gagtctgtta atatggctgc aacatggaaa cttcctgtta
    14341 ttttcttcat catcaacaac cgttatggaa tttcaatgag catcaataat gcaacaaata
    14401 caccacactt atacacacgt gcagaagctt acggaattcc tggtttctac tgtgaagatg
    14461 gcaatgacgt gatggctgtc tatgaaacaa tgggcaaagc cgttgaacat gttcgtggtg
    14521 gaaatggccc agctattgtt gaggtagaat cataccgttg gtttggtcac tcgactgcag
    14581 atgctggtaa ataccgtact aaagaagaag tggatgagtg gaaagaaaaa gatccaatga
    14641 tcaaatatcg tacttatctg acaagcgaag gcattgccac tgatgacgaa ttggatgcta
    14701 ttcaagcaca agtcaaaaaa gaagttgacg atgcttatga atttgcacaa aacagtccag
    14761 atccagaact ttcagtagcc ttcgaagacg tttgggttga ctaagatcac cttgtcagta
    14821 agaagcaatc gtatttgaat aataaatgga gaaataaaaa tgatgtcaga aacaaaatta
    14881 atggctttgc gtgaagcagt caaccttgct atgactgagg aaatgcgcaa ggacgaaaac
    14941 attttcctta tgggagaaga cgtaggggtt tacggaggag acttcgggac ttctgttgga
    15001 atgattgaag aatttggtcc taaacgtgtt aaagataccc caatttcaga agctgctatc
    15061 tctggtgcag ctattggtgc agcgattaca ggactacgtc caattgtcga cgttaccttc
    15121 atggatttcc ttaccatcat gatggacgct atcgtgaata atggtgctaa aaataattac
    15181 atgttcggtg gaggccttat tacccctgta accttccgtg tggcatcagg ttctggtatt
    15241 ggttccgctg cgcaacactc acaatctctt gaagcatggt tgactcacat tccaggaatc
    15301 aaagttgttg ctcctggtaa tgccaacgat gctaaaggct tattaaaatc agctatccgt
    15361 gataataaca ttgttctttt catggaacca aaagcgcttt atggtaaaaa agaagaagtt
    15421 aaccaagatc ctgacttcta tatcccactt ggcaaaggtg acatcaaacg tgaaggaact
    15481 gatttgacaa ttgtgtcata tggtcgtatg ttggagcgtg tccttcaagc ggctgaagaa
    15541 gttgcagcgg atggtattaa cgttgaagtt gttgacccac gtaccctcat cccacttgat
    15601 aaagagttga ttattgaatc tgttaagaaa acaggtaaat tgatgcttgt caacgatgcc
    15661 tacaagaccg gtggattcat tggggaaatt gcaaccatga ttaccgaaag tgaagctttt
    15721 gattaccttg atcatccaat cgttcgtctt gcaagtgaag atgttccagt accttatgca
    15781 cgtgtacttg aacaagcgat cttaccagac gttgagaaaa tcaaagctgc cattgtgaaa
    15841 atggcaaaca aaggcaacta gaagataagg caagtggtct gataaaggct atgtttatca
    15901 gtaacgtctc agctaaaaac tattttgaaa gtttttagaa gaactgagtt gtcttatccc
    15961 gtgtcgcggc acctcacctt tcgtatgttt tcgtagcaag gtgaagatgt tgatggcgct
    16021 tatcaaatcg tgaaaggatg tagaaatggc atttgaaatt attatgccaa agctgggcgt
    16081 tgacatgcaa gaaggcgaga tcatcgagtg gaaaaaacaa gaaggtgata ccgtcaatga
    16141 aggtgatatc cttcttgaaa tcatgtcaga caaaaccaat atggaacttg aggcagaaga
    16201 ctcaggtgtg ctattgaaaa ttgtccgtcc agctggtgat actgtacctg taactgaagt
    16261 tatcggttac attggtgcag agggtgaatc agtagatact attgcttcaa gtgaaaaaac
    16321 aacagaaatt ccagttcctg cttcagcaga tgctggacca acagttgctc caaaagaaaa
    16381 tgtggcaagt ccagctcctc aagtggcagc gacagctatt ccgcaaggaa atggcggaaa
    16441 agttcgtgct actccagctg cacgtaaggc agcagcagaa atgggcattg accttggcca
    16501 agttccagga acaggaccaa aaggacgtgt ccataaagaa gacgttgaaa actttaaagg
    16561 tgctcaaccg aaagcttcac cacttgctcg taaaattgca gcagacaaag gtattgattt
    16621 ggcaaccgta tcaggtactg gctttaacgg taaggtcatg aaagaagaca tcaaggctat
    16681 tcttgaagtg gctaaaccag ctgaagcaaa agcaccagca gctaaagaag aaaaagttgt
    16741 tgaccttcca gaaggtgtgg aacacaagcc aatgtcagct atgcgtaagg caatctctaa
    16801 aggtatgaca aactcttacc ttactgcgcc tacctttacg cttaactacg atattgacat
    16861 gacagagatg attgcccttc gtaagaagtt aattgaccca atcatggcta aaacaggcct
    16921 taaagtcagc tttacagact tgattggtat ggcagtggtt aaaaccttga tgaaacctga
    16981 gcatgagtac atgaatgctt ccctcatcaa tgatgctaat gatattgaat tgcaccgctt
    17041 tgtgaacctt ggtattgccg taggtcttga tgatggtctt atcgttcctg ttatccatgg
    17101 ggctgacaag atgagcttgt cagatttcgt gcttgcttca aaagatgtga ttaaaaaagc
    17161 gcaaactggt aagttgaaag cagccgaaat gtctggatca accttctcta tcacaaactt
    17221 gggaatgttt ggtacgaaga catttaaccc aattattaac caaccaaact cagcaattct
    17281 tggtgttgga gcaactatcc caactccaac ggttgtggat ggtgagattg ttgcccgtcc
    17341 aattatggca atgtgcctaa ccatcgacca ccgtttagtt gatggtatga acggtgcaaa
    17401 attcatggtt gatctcaaga aattgatgga aaatccattt gaattgttaa tctgatcaat
    17461 cagttttaaa caagaaaagc attcaataat aaaagggatt ttgctaagtt tagacttggt
    17521 gcccttttct caaaaatata gaaaggatgt agaacgagga gctctcatgc aaatgagtga
    17581 taagcaattg aatccgagcg aaaagctcgg ataaaaatgg taagagttgg ctaatcttag
    17641 cgtcgtagac gtctgaactt tcctcaattt ttgtttcgga aagtcctagt cgtcctgacg
    17701 tgggtgcgtc aacgaaatca aagatttctg acttaccgca aaaattcaat cgctttctcc
    17761 ttgctcttgg tatcttaaat tatggctgtt gaaattatta tgccaaaact cggtgttgac
    17821 atgcaagaag gtgaaatcat cgagtggaaa aaacaagaag gtgatactgt caatgaaggc
    17881 gatattcttc ttgaaatcat gtcagataaa accaatatgg aacttgaagc agaagactca
    17941 ggtgttcttc ttaaaattac acgtcaagca ggtgaaacag tacctgtaac agaagttatc
    18001 ggctatatcg gtgctgaagg tgaatctgtt gaggtttcta gcccagctgc ttcagatgtg
    18061 aatgttgctc gtacaacaga agatttagaa gctgctggac ttgaagtgcc aaaagcacca
    18121 gctcaagctg cttcagctgc accaaaagct gcacttgctg atgatgagta tgacatcatc
    18181 gttgttggtg gtggccctgc tggttattat gcagctattc gtggtgctca acttggtggt
    18241 aaaattgcca tcgttgagaa atctgaattt ggtggaactt gcttgaacgt agggtgtatc
    18301 ccaaccaaaa cttaccttaa aaatgctgaa atccttgatg gtattaagat tgcagcagga
    18361 cgtgggatta accttgcctc aactaactat accattgaca tggacaaaac agttgacttt
    18421 aaaaacaccg ttgttaaaac cttaacaggc ggcgttcaag gtcttctaaa agctaataaa
    18481 gtcactatct ttaatgggct tggtcaagtc aaccctgaca agactgtaac cattgggtca
    18541 caaaccatta agggtcgcaa cgttatcctt gctacaggtt ctaaagtatc acgtatcaat
    18601 atcccaggta ttgactctaa acttgtctta acgtcagatg atatccttga ccttcgtgaa
    18661 atgccaaaat cactagcagt tatgggcggt ggtgttgttg gtatcgagct tggacttgtt
    18721 tgggcatctt acggtgtgga tgttaccgtt attgaaatgg ctgaccgtat tatcccagct
    18781 atggataaag aagtctctct tgaacttcaa aaaattcttt ctaagaaagg catgaagatc
    18841 aaaacatctg ttggtgtctc tgaaattgtt gaagcaaata accaattgac cttgaaactt
    18901 aacaatggtg aagaagttgt cgctgaaaaa gctcttcttt ctatcggtcg tgtaccacaa
    18961 atgaacggtc tggaaaatct taaccttgaa atggatcgta accgtatcaa agttaatgac
    19021 taccaagaga catcaattcc aggtatctat gcgccaggtg acgttaacgg aacgaaaatg
    19081 cttgctcacg ctgcttaccg tatgggtgaa gtggctgcag aaaatgcgat acatggcaac
    19141 acaactcgta aagctaacct taaatacaca ccagcggctg tttacacaca ccctgaagtg
    19201 gcaatggttg gtttaactga agaacaagcg cgtgaacaat atggtgatgt gcttattggt
    19261 aaaaacagct ttactggtaa tggacgcgcg attgcttcaa atgaagcaca tggttttgtt
    19321 aaagttattg ctgatgccaa ataccacgaa atcttaggtg ttcatattat tggtccagct
    19381 gcagctgaga tgattaacga agcagctact attatggaat ctgaattaac cgttgatgaa
    19441 ttgttattat caattcatgg acacccaacc ttctctgaag tgatgtacga agcctttgca
    19501 gatgtgcttg gcgaagctat ccataaccca ccaaaacgta agtaaaacgt ctttgtctta
    19561 ttaactaatg aaaaatatca tcacataaca gatcacaaaa aagactagca caactatgaa
    19621 ctgcacccca aacgttagat ataaaaccct aacgtttggg gtgtttttgt atgacattaa
    19681 gctatgaaga taagctagac atttagcgct aaaaaaacga gagaactccg tttgaaagaa
    19741 gcatctctga aaagatgaag acaaaaaacc attataaaga atggacaaag acgagctctg
    19801 attagacttt cttttaagaa cggctaaatt gactcgttct acctactatt atcatcgatt
    19861 attgcaacaa taaacgtatc aaaataaaac gaaaaggact tagtcctcta caacacagaa
    19921 ctaaatcctt tacttcaaat agagtagcca acttttgggg ctcagtgcag tttccagttt
    19981 ttttgtcttt aataacgttt cattgttaac ccttactttc caataacagc taaatcctta
    20041 agtctttctt acgaaagggt tttgtgatat ggttaaaaga agcaactaaa gctccaccta
    20101 agaattctaa agaggaggac tgatacccag tatgcggtaa gcgtcgttgt cttttgtggg
    20161 gaattttatg agagttaaga gcattgtttt tagctgcaat tccttgatga gcaagctttt
    20221 attgttgatt ttgcttgaca ggatgaggaa aactataaaa gccttgatga gaaagattat
    20281 gatttgaaaa catcgttgct tttttttcat agtgaatgac gtgcatctgt tgactatcat
    20341 gatcgtagac agcggccagt ttgtcattgt tttctaacaa gtcgatatca agcttgctaa
    20401 tataggtttc aaattcttga cgagtcatat ttggaagcat catataggca taacgatcgc
    20461 catcttgagt atggttttgc atgatagtga taaaggtatt tgaaacttct ttgatggctt
    20521 ctggtgattt gtcatcagct tttatgtttt gccatttccc tgtttgaagt gccttactta
    20581 tgctaagtgt tgttggcttg aagaagtagt aaccaatatt ttgagcggga tcatcacttt
    20641 caaggaaaat acttttagtg tttgtaaaat caactagctg attattcaag tcaacgggtt
    20701 gattgttaac ataagaacag taagggtgct tttgattttc ttttcgttgc tcaatagttg
    20761 tatacgcctt gtgagatgac tggtttttga tattgctacc aacaaagatt attttgtttc
    20821 ctaagataaa ccacccttta ttgagagtga ggcttttatt ccaattagtg aaggtcatag
    20881 cagctagagc acttgtgtta ttaagttttt tacttgcaac aaaagcgtca tcagagagac
    20941 tagtcatgcc aacttgttga tagttcgttt taatattctc aggagttccc tctagtggtt
    21001 tttgctcagt ttctgtggtt ccaggtaagc ggtagggatt taccgttgcc caatagtttt
    21061 cactgtagtg tcctaaatcg ttattgtata ggtaaaacat tccatcagaa gtaaaccagc
    21121 catgaagatt ttcattattc atagcttcat aattttgagt tcgattcgaa aacattgata
    21181 gaccaaaagc aaaatcgtgt ttattattat atagtgccaa tttatccata ctattgaaac
    21241 tagctacgta actatcaagt ttttggactg gaacagaagt atcacttagc agttctttca
    21301 taagtttgat atcgtgatag gttttcaaat tatcatagac attgtaaaaa gcattccctt
    21361 gtgtgacgag tgtttttata cgtgttttaa gtgccaaacg gtgaggctct tcagacatgt
    21421 cagcaatacg taaaatagca cgaagtgctt caataccagc aacatgagat tgagcattaa
    21481 aacgactgat agaacgccct cgagtcatat ccatcatttc tccacgaacg atgataggga
    21541 aaaaagaatg gttaatccaa tgatagatag tagccatttt atccgcttct ataggagact
    21601 ttgttttttg aataatagga attaattgcg ataagccatc tataagaaca ttaccgtaag
    21661 ctccagtgta agcaatgcct tttttataaa gtggactttg agcgttagta accacgtgat
    21721 caattaaaga accgtcttgg taaaaaccat ttccttcgtc aactagcgtg aaaactttct
    21781 caattgcttt gattgtatca ctaatttcga gatcatcttt acgaagaata ccggaaatga
    21841 gtttaacacg tcccatatca attaaatttc cgctactggc ttcaaaaggt gaaaaattgg
    21901 cagcgcgaac cctaaaacga gtagggtcag gcacaaattt ttcgattgga gctgtgtatt
    21961 taaggatttc ttcttgagta aaataaggat acatcaagga taaggtatta ttaatagcac
    22021 gaggagttcc aatttcataa acccaccaat tttctttgtt ttcttttcca gttgtttgat
    22081 gattttcacg atttagatta taagcgtgtt catacatgaa ggccataccg tcttttacaa
    22141 tagcaatagc tttactatct tgataatagc atgattcagg attagtgatc tgttttgcta
    22201 ttttttcaat attgcggtaa gttttcgtga tattagtaga agcggaataa tcctttgcat
    22261 gttcccaaag gtaagttcta ttttcgtggt caggcccttg atagctttta ataatgtttt
    22321 gagcatcctt ttcagcttta ttatgaaaag tgaccatgtc aggattggtt ttaacataag
    22381 catcgttgcc tgcgataata ctgttccatt ggtctaacaa ttcagtatag tagtcttttt
    22441 gttgtggctg tactaccttt ttttcgctat ctgtagtagt gagcgtttgc gtttgaaagt
    22501 aagtattatt aggttctgaa tttgaagtca gtgtatcggc ataaatggca gttccttggc
    22561 ccatcatagc aaagctaagg aataggtttg aataaagtag taattgttta tggtgtgtgc
    22621 aaaaataagt attcactgat aaattcctcc aatataaaaa tgagataata aaagtagatt
    22681 ggtttactaa gtaaaaatat accacgttaa agtattttta taaaccctta cataaataat
    22741 ggctgagttt ttgtgcacta ataagtgtag gtactgaaga tgtcatacag aataggacac
    22801 ttgtctttta tatttgtttt cattatacta gagaggtaga ttacattttt gaaaggattt
    22861 tttctcctat gaaatacatc gttaacaaaa gtcacaatcc tgcctttaac atcgctttgg
    22921 aagcctatgc ttttagagaa ctagtggaag aagacgaatt gtttatcctt tggatcaatg
    22981 agccagctat tattattggc aaacatcaaa acaccattca agaaatcaat aaagaataca
    23041 ttgatgaaca tggtattcat gttgtgcgac gtttatctgg tggtggtgcg gtttatcatg
    23101 atttgaataa cttgaactac actatcattt caaataaaac agcggaaggc gcatttgatt
    23161 tcaaaacctt ctcacagcct gtgattgcga ctttagctga tttgggtgta acagccaact
    23221 ttacaggccg taatgatatt gaaattgatg gtaaaaaaat ctgcggtaat gctcaagctt
    23281 actacaaagg tcgcatgatg caccatggtt gccttttgtt tgatgtggat atgaccgttc
    23341 ttggcgatgc tcttaaggta agtaaggata agattgagtc taaaggagtg aagtctgttc
    23401 gtgctcgcgt gaccaatatt ttaaatgaat taccagaaaa aattaccgtt gaggaatttt
    23461 cagataaaat cttgaccaag atgaaagaaa cgtacccaga catgacagaa tatgtcttgt
    23521 cagaggatga gttggctaag attgaacaat ctgccaaaga gcaatttggt agctgggatt
    23581 ggacctacgg caaagcgcca gaatatacga ttgaacgcaa tgttcgttac cctgcaggta
    23641 aaatttcaac ctttgcaaat gttgaaaatt ctatcattaa aaaccttaaa atctatggtg
    23701 atttctttgg aatcaaagat gtgcaagaca ttgagaactt attaattggt tgtaaatatg
    23761 agtaccgtga tgtttttgaa cgtttaaaaa cgattgatac gacccagtac ttctcacgca
    23821 tgaccgttga agaagttgct aaagctattg tttcttagtg gttttaatca cttaagaagc
    23881 tctgtcagaa gaaaaaacta taaaactcct aagcgaaata tcgtgtcctg cttaggagtt
    23941 tttgtttgat gacatgaaag aagaacttaa gctttatcaa aggcagcttt acgtttaatg
    24001 tcggcatatt cttcagcgac ttcttgtttc agtatatcat catagctagg tagtgtaata
    24061 gctgatccgt acttttcttt gagagctgtt gttacgagac ggtaagcaag gttcacgttg
    24121 cgtgataaga taggaccatg gaaataactg ccgtagacgt ttttatagtg aacaccttca
    24181 gtttggtctt ccttattatt accattgcca taaaccactc gtccaagtgg cttctcatca
    24241 tcgtataaga aggtacgacc ttgatgattt tcaaagccat aataggtttc gttaaattcg
    24301 tcattatgaa ttttaatatc tccaataaag cgattttggt gctgattaag ggtgtagtgt
    24361 cccataattc caagtccatc aattttaacc ccattagctt ggacatagta ttgccccagt
    24421 aattggaagc caccacagat ggcaagcacc actttattct tagcgatata atccgctaaa
    24481 gcagcttttt tgctaggcaa atccttagca acgatggttt gctcatagtc ttgtccacca
    24541 ccaaaaaaaa caaggtcgta gtaatcttgg tcaaaggcat cattgaggga aacaatatca
    24601 acggtaactc tagctccaag tttttcagcg acatacttga gcatcaagac attcccattg
    24661 tcaccgtagg tattcatcag gtttccgtag agatgagcaa tgtttaggtt atagaggtag
    24721 tcagtgtttt ctggagattt tagtgaagtg taagtcatta gttcatctcc ttttcaacaa
    24781 catggcggtc ggctagcaag ctacggaatt ctaacattgc agtataggtt gctaaaatat
    24841 aagcatgttt gctttcttgt ttttcaatag cttccatgat ttgctcgagc ttttcagctt
    24901 gttttatctt agtgtcgtca aatcctgtga ctctaagtct tctggcaatt tcagagtgac
    24961 ggacgccgcc agcattaatt tctgtaatgg gcatttgggt aatgagttca aaattagcat
    25021 cccaaatcca gctggtatca atgccgtcag cgtaattagc atttaaaagc acagataagc
    25081 taaatgggta atcagctagc tgaatcattt caagcgcttg actggctcca acaggattct
    25141 tgataaggat aagggtgcat gatttatcac caatagtaaa agtttcttgt cttccaaaaa
    25201 ccgccttact tttgttaaag cccgccttga ttttctcggg agaaacaccg aaaaattcag
    25261 caacagaaac cgcagcaagc gcattgtaaa tattataaag accaccaaca tttatcttgt
    25321 agttttgtcc atcaataaca aattcagaac tttggtgagt aatagcggtg agttcagtta
    25381 atcgataatc caactgtggt ctcttgaagc cacaatttaa acaaataaag tctcctagat
    25441 tcgcataagt attgagacga tactgaagaa tatgttcgca ttttggacat aaaatccctt
    25501 ctgtgttgta atgagctagc tgcggagcat gcttagcagt atcaaaacca taatactgaa
    25561 ctggattaac tatgtcctta gaagagaaaa taggactatc tccattggct agaatagttg
    25621 cttttggagc atttcgagca ccatctacaa tcatctgata agtagtataa atctctccgt
    25681 agcggtccat ctgatcccta aaaatattag tataaacaaa aagactaggt tttaagtaag
    25741 tggtaattct aggaagacta gcttcgtcaa tttctaaaac agcaatttgc cttccagatt
    25801 tccctttttt agcagctaaa aaagtagaag taattccagt aatcatattg gcaccacttg
    25861 gatttgtgat tatctcgcca aatgcctctt tcaaaatacc gacagtaaga gcagttgtta
    25921 acgttttacc attagtacca gtgacgacca caatatcata gtctttagac aaatccttta
    25981 aaatatcttt attacaagct agagccaatt gaccaggata agtagatcct cgccctagtt
    26041 ttgttaaaat ggattgagca gctttgccag caataatgcc gagtaatgtc ttcattttca
    26101 tgcttatatt ttatcataag tttattgatt ttagataggg aaaaatcttt gatcatgata
    26161 tgatataata tagctaataa cttttttgat atagaaatga gagttgtatg aataatttat
    26221 ctagtatcga tattaaattt ttattaagct tatttgcgga tccttggctg ctggcagtgc
    26281 atcttttaga tattctaatt gttgcctatt tgatttatcg ttttattaaa gcattgactg
    26341 gaactaaaat catgtcttta gttcaagggg tcattttctt tttggttctt cgttttattg
    26401 cagagtggat tggctttacg acaatcacat acttaatgaa ccaagtcatt acttatggtg
    26461 taattgcagg agtagtcatt tttacccctg aaattcgggc aggactggag aaatttggtc
    26521 gttctacgca agttttttta caaaaacagt acgtcagcag tgaatctgct ttggtcgatg
    26581 ctttgattaa atctgtggcc tatatgggtc cacgcaagat aggtgcactg attgctattg
    26641 aacagactca aaccttacaa gaatatattg cgacaggaat tccgctgaat gccgatattt
    26701 caagtcaact actcatcaat atttttattc caaatacgcc gcttcatgat ggagctgtta
    26761 tcgttggtca gaataagatt gtggcagcct gtgcttactt gcctttgtca gaatcaaagg
    26821 caatttccaa agaatttggg acccgtcata gagcggctat tggattatct gaaaactctg
    26881 atgcactaac tatcattgtt tcagaagaaa caggagctat ttcagtaact cgcaaaggcc
    26941 aatttttaca cgatttaagc acagatgaat ttgaaacggt acttaggacc tacctgatga
    27001 gtgattcaaa tgttagttta ccatggtata agaaaattct aggagggaaa tctaaatgaa
    27061 acgattttta aatagtcgtc cttggttagg aatggtatca gtcttttttg cgattctcct
    27121 ttttttaact gcagcatcga gcaatcataa taattctagc tcgcaaattt atagcccgat
    27181 tgaaacctat acgcatagcc ttaaagatgt accaattgat atgaagtatg atagtgacaa
    27241 atattttatc agtgggtatt cttatggtgc ggaagtttat ctaacctcca ctaatcgtat
    27301 caaattagat tctgaagtga acaatgatac acgtaatttt aagattgtgg cggatctaac
    27361 acatagtcat ccaggtacag taaatgtcaa cctaagagta gaaaaccttc cttctggggt
    27421 gacagctacc gtatctccag ataaaatatc agtcacaatt ggcaaaaaag aatctaaggt
    27481 atttcctgtt agaggaagcg ttgatgctaa acaaattgca aatggttatg aaattagcaa
    27541 aattgaaacg ggggttaata aggttgaagt gaccagtgat gaatctacca ttgctttaat
    27601 tgatcacgtt gtggcaaagt tacctgatga tcaagtgtta gataggaatt atagtagtcg
    27661 agtgacctta caagctgtct cagctgatgg aactatttta gcaagtgcaa ttgatcctgc
    27721 aaaaacaaat ttatcagttg ctgtaaaaaa aataacgaaa tcagtcccga ttagagttga
    27781 ggcagtgggg atgatggatg atagcttatc agatattcaa tacaaattgt caaaacaaac
    27841 agctgttatc tcaggtagtc gagaggtctt agaagatatt gatgaaatta ttgcagaagt
    27901 taacatttct gatgtcacta aaaatactag taagaccgtg agtttgtctt ctagtcaggt
    27961 gtcaattgag ccgtcagtag tgaccgttca gttgacaacc accaaaaaat aatggataat
    28021 aactaggaaa attgaatgga ggaagccatt aggcttatat aaattatggg aaaatatttt
    28081 ggaacagatg gtgttcgtgg tgaagcaaat gttgagctga cacctgagtt agcttttaaa
    28141 ctgggccgat tcggtggtta tgttttaagt caacatgaga ccgaaagacc taaagttttt
    28201 gtggcgcgtg acacccgtat ttcaggagaa atgttggagt cagccttgat tgctggtcta
    28261 ctatctgttg gtattgaagt ttataaactt ggtgttttag cgacacctgg tgtctcttat
    28321 ttagttagaa ctgaaaaagc aagtgcaggt gtgatgattt ctgcaagtca taaccctgcg
    28381 cttgacaatg gcatcaaatt ctttgggaat gacgggttta agttagctga tgaccaagaa
    28441 ttggaaattg aagctctctt agatgctccg gaggacacgc ttcctcgccc gagtgcagaa
    28501 ggacttggaa ccttggtaga ttatccagaa ggacttcgta aatatgaaaa gttcttggta
    28561 acaacaggta ctgacttaag cggtatgaca gttgccttag acactgctaa tggagctgct
    28621 tcagtgtcag cacgtgatgt ctttttagat ttaaatgcag aaattgctgt cattggcgaa
    28681 aaaccaaatg gtcttaatat taatgacggt gttggttcaa cgcatccaga acaacttcaa
    28741 gagttagtta aggaaacagg agcagatctt ggtttagcct ttgacggcga tagcgaccgt
    28801 ctgattgctg tggacgaaac tggtgagatt gttgacggtg atcgtattat ctttatcatt
    28861 ggtaaatact tgtcagaaaa agggcttctt gctcacaata ccattgtcac aacggtgatg
    28921 tctaacctcg gttttcataa agctttagat aaacaaggta ttaataaagc aattacagca
    28981 gttggagacc gctatgtggt tgaagaaatg cgtagctcag gatacaatct cggtggtgaa
    29041 caatcaggcc atgtcattat catggactac aataccactg gagatggtca gttgacagct
    29101 atccaattag ccaaggtgat gaaggaaact gggaaatcac tttcggaatt agctgctgaa
    29161 gtaaccattt accctcaaaa actggtgaat attcgtgtgg aaaacagcat gaaagaccgt
    29221 gctatggaag ttccagctat tgcgaacatc attgcaaaaa tggaggatga aatggctggt
    29281 aatggtcgta ttctcgtgag accaagtggt acagaacctc ttcttcgtgt catggcagag
    29341 gcgccaacag atgccgaagt tgattattat gtcgatacta ttgctgatgt cgtccgtaca
    29401 gaaatcggat gcgataacta acgagttgag tacaaacaag aaaccttatt tctaaggctt
    29461 ctgtcaacaa ttggaaagag gcttggggcg tttagcccaa gtctcttttt ataaattgct
    29521 aaagtagaag agaaaggata tcggatgaca aaacagcaaa tcgaaaaact agcggactta
    29581 ctgcctcctt ttgcagccac actttactta gatatgattc ctgaatttca ggaaggttat
    29641 gcttcatatg tttatcaaac ccaaaaagaa gatattcaaa agcgccgcat caagcagtta
    29701 actaaaaatt ttgaacgatt actagatacc ccatcttttt atgtgatgcc tgtgacaaga
    29761 aaaacagcag agcaattgct agcagataaa ggcctagctt atcatttgtt atcgacagtt
    29821 gcagctaatc aagtgtttgc ggctgctgtt aacgaggatc agacgctttt tcaagtgctt
    29881 cgaaatggag caagagtagc ctttgtgatt cttcaagaaa agggggaatt tctagaaatg
    29941 actttaggga ttcttgaaac agtgacagaa aacgaggttc cagcagctat tgtggaggct
    30001 gtccagacat atcttctgac agatatgcaa gagaaactcc cttctttaag cattatggtc
    30061 agtcaagaat caagcaagct tttttaccaa gaacaagggt ttgttttgct agctaagggt
    30121 tgcaagccag gaaacgaaaa tgactctgac gtttgtcagc tcgtaaaata cttttccaag
    30181 ccatgaagaa tcaagggaaa tggtttattc atagaaacat tttatcatca aagtggtata
    30241 ataagaccat gtcaaaaaaa cctacttcag cctatgtgca cattcctttt tgcacacaaa
    30301 tttgttatta ttgcgatttt tcaaaagtct ttatccaaaa tcaacctgtt gatgcttatt
    30361 tgaaagcctt gattcaagaa ttcgaatcct atgacattca tgacttaaag actctttata
    30421 ttggaggagg tacgcctaca gctatcactg ctaaacagtt ggagtatctc ctaaatcacc
    30481 ttgaacgaaa cctcaattta gatgatcttg aagaattcac aattgaggca aatcctggtg
    30541 atttgacgcc agaaaaaatt gcggtgcttc agaggtcagc tgtcaatcgg atttccttgg
    30601 gggtgcagac ttttaataac aagcaattaa agcagattgg ccgtagccat aatgaagaac
    30661 aaatttatag caccattgcc aatttaaaaa ctgcaggctt tcacaatatt tccattgatt
    30721 taatttatgc cttgccaggt caaaccttag aacaagtcaa ggaaaatgtt gctaaagctt
    30781 tggcacttga tattccccat cttagtcttt atagccttat tttggaacat cacaccgttt
    30841 ttatgaacaa aatgcggcgt ggtaaactta acttaccaac ggaagacttg gaagcagaaa
    30901 tgtttgagta tattatttca gaaatggaag ctaatggttt tgagcattat gaaatttcca
    30961 attttaccaa accaggtttt gaaagtcgcc ataacttgat gtattgggat aatgtggagt
    31021 attttggatg tggtgcaggg gcttcaggtt accttaatgg cattcgttat caaaatcggg
    31081 tgcccatcca gcattatctt aaagcggttg aagcaggaaa cgctagacta aatgaagaag
    31141 tgctgcgcaa agaggaaatg atggaagagg aactcttttt gggcttacgt aaaaagacag
    31201 gagtctccat ccagcggttc caagaaaaat ttggtatttc ttttgaggag cgttatggaa
    31261 atattgttag ggagcttcaa aatcaaggac tgcttgtcaa agatgacgcc tttgtcagaa
    31321 tgactaaaaa gggtcttttc ttaggtgatt ctgttgctga gcggtttata ttagattagg
    31381 agagtattat gggattaagt tatcaggagg agttgacact tccttttgaa ttatgtgatg
    31441 tcaaatcaga tataaaattg ccccttttat tagactattg tttgatggtt tctggtagac
    31501 agtctgcgca attaggacga agtaacaaca atcttttagt tgattacaag cttgtttgga
    31561 ttgtaacgga ttatgagatc actattcatc gcttgccaca ttttcaagaa accatcacca
    31621 ttgaaacaaa agccctttcc tataataaat ttttttgtta tcgccaattt tatatttatg
    31681 atcaagaggg gggtctttta gtggatatct tagcctattt tgctttgtta aacccagata
    31741 cgcgaaaagt ggcaactatt ccagaagatt tagtagcgcc ttttaagact gattttgtta
    31801 aaaagctaca ccgtgttcct aaaatgcctc ttttagaaca atcaattgat cgtgattatt
    31861 atgtgcgtta ttttgatatt gatatgaatg gtcatgtcaa caacagtaaa tatttagatt
    31921 ggatgtatga tgtgttgggg tgtgcgtttt taaaaacgca tcagcctctt aagatgactt
    31981 tgaaatatgt taaagaagtc tcaccaggcg gtcaaattac ttccagttac catttggacc
    32041 aattaacttc ttaccatcaa atcatctcag atgggcagct gaatgcccaa gccatgattg
    32101 aatggcgagc gattaaacaa acagaaagcg agatagacta gtgccttata agggttattt
    32161 aattgattta gacggaacga tttaccaagg gaaaaaccgt attccagcag gggagcggtt
    32221 tatcaaacgc ctacaagaaa aaggcattcc ctatttatta gtgactaata ataccacaag
    32281 aacacccgaa atggtgcaaa gcatgctggc taaacagttt aatgttgaga caggcattga
    32341 gactatctac acagctacca tggcaaccgt tgattacatg aatgacatga accgtggcaa
    32401 gacagcttac gttattggag aaacagggct caaatcagct attgcagcag caggttacat
    32461 agaagaactt gagaatcccg cttacgtggt ggttggttta gacagtcagg tgacctatga
    32521 gatgttggct atagccacct tagctattca aaaaggtgcc ctctttattg ggacaaatcc
    32581 tgatttaaac attccaaccg aacgtggttt gatgccagga gcaggtgcat tgaatgcctt
    32641 actagaagct gccacacgtg taaaacctgt ttttattggc aagcccaacg ctatcattat
    32701 gaataaatca ctagaggtat tgggcattca gcgctctgaa gccgtcatgg ttggcgataa
    32761 ttacttgact gatatcatgg caggtattca aaatgatatt gcaacgatcc tcgtgacaac
    32821 aggctttacc agacctgaag aggtaccaac cttaccaatt cagccagatc atgtcctatc
    32881 tagtcttgat gagtggaggt tgtgatggta gaaaacacta aattactatg tagctgggta
    32941 tggttattag cgttagctat tctcataacg atctattcaa cgtggctgtg gtatcctctt
    33001 gaggtggacc atctaaagtt agaacaagtt gtttttatga gcaaggatgc tatcttgcat
    33061 aactataacg gactactaaa ttacctcacc aatccttttg taacaaggtt ggaatttgct
    33121 aattttcact catcggcaga cggactcaag cattttgcag atgtgaagtg gctttttcac
    33181 ctaactcaag tcgtttttct tggcctcctt tacccaaccc ttaagacttt cacacaaagg
    33241 ttaaaaacca aacgtttctg gctccttcaa aaacctttaa tactagcagc tttgtttcct
    33301 cttatgattg gtctaatggc tagtttcatt gggtttgaac atttttttac tctttttcat
    33361 caggtgcttt ttgtaggaga tagcagctgg ctctttgatc ccttgaaaga tcctgtgatt
    33421 tggatccttc cagaagtctt tttcttgcac tgtttccttt tctttatgat agtttacgaa
    33481 atcatcctgt ggagcttagt aggtttagca agatggcagc gcctaaatgt agaatgataa
    33541 aacaagcgtt ttgaaagcgc ttgtttttta gtttgcagtc agagtagaat agaagtatca
    33601 aaaaaaagca ccgactcggt gccacttttt caagttgata acggactagc cttattttaa
    33661 cttgctatgc tgttttgaat ggttccaaca agattatttt ataactttta taacaaataa
    33721 tcaaggagaa attcaaagaa atttatcagc cataaaacaa tacttaatac tatagaatga
    33781 taacaaaata aactactttt taaaagaatt ttgtgttata atctatttat tattaagtat
    33841 tgggtaatat tttttgaaga gatattttga aaaagaaaaa ttaaagcata ttaaaccaat
    33901 ttcggaggtc attaaaacta ttagtgaaat catcaaactc attatggatt taatttaaac
    33961 tttttatttt aggaggcaaa aatggataag aaatactcaa taggcttaga tatcggcaca
    34021 aatagcgtcg gatgggcggt gatcactgat gattataagg ttccgtctaa aaagttcaag
    34081 gttctgggaa atacagaccg ccacagtatc aaaaaaaatc ttataggggc tcttttattt
    34141 gacagtggag agatagcgga agcgactcgt ctcaaacgga cagctcgtag aaggtataca
    34201 cgtcggaaga atcgtatttg ttatctacag gagatttttt caaatgagat ggcgaaagta
    34261 gatgatagtt tctttcatcg acttgaagag tcttttttgg tggaagaaga caagaagcat
    34321 gaacgtcatc ctatttttgg aaatatagta gatgaagttg cttatcatga gaaatatcca
    34381 actatctatc atctgcgaaa aaaattggta gattctactg ataaagcgga tttgcgctta
    34441 atctatttgg ccttagcgca tatgattaag tttcgtggtc attttttgat tgagggagat
    34501 ttaaatcctg ataatagtga tgtggacaaa ctatttatcc agttggtaca aacctacaat
    34561 caattatttg aagaaaaccc tattaacgca agtggagtag atgctaaagc gattctttct
    34621 gcacgattga gtaaatcaag acgattagaa aatctcattg ctcagctccc cggtgagaag
    34681 aaaaatggct tatttgggaa tctcattgct ttgtcattgg gtttgacccc taattttaaa
    34741 tcaaattttg atttggcaga agatgctaaa ttacagcttt caaaagatac ttacgatgat
    34801 gatttagata atttattggc gcaaattgga gatcaatatg ctgatttgtt tttggcagct
    34861 aagaatttat cagatgctat tttactttca gatatcctaa gattaaatag tgaaataact
    34921 aaggctcccc tatcagcttc aatgattaaa cgctacgatg aacatcatca agacttgact
    34981 cttttaaaag ctttagttcg acaacaactt ccagaaaagt ataaagaaat cttttttgat
    35041 caatcaaaaa acggatatgc aggttatatt gatgggggag ctagccaaga agaattttat
    35101 aaatttatca aaccaatttt agaaaaaatg gatggtactg aggaattatt ggcgaaacta
    35161 aatcgtgaag atttgctgcg caagcaacgg acctttgaca acggctctat tccccatcaa
    35221 attcacttgg gtgagctgca tgctattctg agaagacaag aagactttta tccattttta
    35281 aaagacaatc gtgagaagat tgaaaaaatc ttgacttttc gaattcctta ttatgttggt
    35341 ccattggcgc gtggcaatag tcgttttgca tggatgactc ggaagtctga agaaacaatt
    35401 accccatgga attttgaaga agttgtcgat aaaggtgctt cagctcaatc atttattgaa
    35461 cgcatgacaa actttgataa aaatcttcca aatgaaaaag tactaccaaa acatagtttg
    35521 ctttatgagt attttacggt ttataacgaa ttgacaaagg tcaaatatgt tactgaggga
    35581 atgcgaaaac cagcatttct ttcaggtgaa cagaagaaag ccattgttga tttactcttc
    35641 aaaacaaatc gaaaagtaac cgttaagcaa ttaaaagaag attatttcaa aaaaatagaa
    35701 tgttttgata gtgttgaaat ttcaggagtt gaagatagat ttaatgcttc attaggtacc
    35761 taccatgatt tgctaaaaat tattaaagat aaagattttt tggataatga agaaaatgaa
    35821 gatatcttag aggatattgt tttaacattg accttatttg aagataggga gatgattgag
    35881 gaaagactta aaacatatgc tcacctcttt gatgataagg tgatgaaaca gcttaaacgt
    35941 cgccgttata ctggttgggg acgtttgtct cgaaaattga ttaatggtat tagggataag
    36001 caatctggca aaacaatatt agattttttg aaatcagatg gttttgccaa tcgcaatttt
    36061 atgcagctga tccatgatga tagtttgaca tttaaagaag acattcaaaa agcacaagtg
    36121 tctggacaag gcgatagttt acatgaacat attgcaaatt tagctggtag ccctgctatt
    36181 aaaaaaggta ttttacagac tgtaaaagtt gttgatgaat tggtcaaagt aatggggcgg
    36241 cataagccag aaaatatcgt tattgaaatg gcacgtgaaa atcagacaac tcaaaagggc
    36301 cagaaaaatt cgcgtgagcg tatgaaacgt attgaagaag gtatcaaaga attaggaagt
    36361 cagattctta aagagcatcc tgttgaaaat actcaattgc aaaatgaaaa gctctatctc
    36421 tattatctcc aaaatggaag agacatgtat gtggaccaag aattagatat taatcgttta
    36481 agtgattatg atgtcgatca cattgttcca caaagtttca ttaaagacga ttcaatagac
    36541 aataaggtct taacgcgttc tgataaaaat cgtggtaaat cggataacgt tccaagtgaa
    36601 gaagtagtca aaaagatgaa aaactattgg agacaacttc taaacgccaa gttaatcact
    36661 caacgtaagt ttgataattt aacgaaagct gaacgtggag gtttgagtga acttgataaa
    36721 gctggtttta tcaaacgcca attggttgaa actcgccaaa tcactaagca tgtggcacaa
    36781 attttggata gtcgcatgaa tactaaatac gatgaaaatg ataaacttat tcgagaggtt
    36841 aaagtgatta ccttaaaatc taaattagtt tctgacttcc gaaaagattt ccaattctat
    36901 aaagtacgtg agattaacaa ttaccatcat gcccatgatg cgtatcttaa tgccgtcgtt
    36961 ggaactgctt tgattaagaa atatccaaaa cttgaatcgg agtttgtcta tggtgattat
    37021 aaagtttatg atgttcgtaa aatgcttgct aagtctgagc aggaaatagg caaagcaacc
    37081 gcaaaatatt tcttttactc taatatcatg aacttcttca aaacagaaat tacacttgca
    37141 aatggagaga ttcgcaaacg ccctctaatc gaaactaatg gggaaactgg agaaattgtc
    37201 tgggataaag ggcgagattt tgccacagtg cgcaaagtat tgtccatgcc ccaagtcaat
    37261 attgtcaaga aaacagaagt acagacaggc ggattctcca aggagtcaat tttaccaaaa
    37321 agaaattcgg acaagcttat tgctcgtaaa aaagactggg atccaaaaaa atatggtggt
    37381 tttgatagtc caacggtagc ttattcagtc ctagtggttg ctaaggtgga aaaagggaaa
    37441 tcgaagaagt taaaatccgt taaagagtta ctagggatca caattatgga aagaagttcc
    37501 tttgaaaaaa atccgattga ctttttagaa gctaaaggat ataaggaagt tagaaaagac
    37561 ttaatcatta aactacctaa atatagtctt tttgagttag aaaacggtcg taaacggatg
    37621 ctggctagtg ccggagaatt acaaaaagga aatgagctgg ctctgccaag caaatatgtg
    37681 aattttttat atttagctag tcattatgaa aagttgaagg gtagtccaga agataacgaa
    37741 caaaaacaat tgtttgtgga gcagcataag cattatttag atgagattat tgagcaaatc
    37801 agtgaatttt ctaagcgtgt tattttagca gatgccaatt tagataaagt tcttagtgca
    37861 tataacaaac atagagacaa accaatacgt gaacaagcag aaaatattat tcatttattt
    37921 acgttgacga atcttggagc tcccactgct tttaaatatt ttgatacaac aattgatcgt
    37981 aaacgatata cgtctacaaa agaagtttta gatgccactt ttatccatca atccatcact
    38041 ggtctttatg aaacacgcat tgatttgagt cagctaggag gtgactgatg gctggttggc
    38101 gtactgttgt ggtaaatacc cactcgaaat tatcctataa gaataatcat ctgattttta
    38161 aggatgccta taaaacggag ctgatccatt tatcagaaat tgatattttg ttattagaaa
    38221 cgaccgatat tgtcttgtcc actatgctgg taaaacggct agtggatgag aatgtccttg
    38281 tcatattctg tgatgataaa cgattaccaa cagctatgct gatgcctttt tatggtcgtc
    38341 atgattcgag tttacagctt gggaaacaaa tgtcctggtc agaaacagtc aaatcgcagg
    38401 tttggacgac gattattgct caaaagattt tgaatcaatc ttgctatcta ggagcatgct
    38461 cctattttga aaaatcccaa tctattatgg atttatatca tggtttggaa aattttgatc
    38521 cgagtaatcg agaagggcat gcagcgagaa tttattttaa tacacttttt gggaacgatt
    38581 tctcaagaga tttggagcat ccaatcaatg caggtctgga ttatggttat actttattat
    38641 tgagtatgtt tgcgcgtgaa gtggttgtgt ctggatgtat gactcagttt gggcttaaac
    38701 acgctaatca gtttaatcag ttcaattttg ctagcgatat tatggaacca tttaggcctt
    38761 tggtggataa gattgtttat gaaaatcgaa atcagccttt tcccaaaata aagagagagt
    38821 tatttacttt gttttcagat acattttcat ataatggtaa agagatgtat ctcacgaata
    38881 ttattagcga ttatactaaa aaagttgtca aagctctgaa taatgaaggg aaaggagttc
    38941 ctgaatttag gatatgagtt atagatatat gagaatgata cttatgtttg atatgccgac
    39001 ggacaccgct gaggaacgaa aagcctatcg aaaatttcgg aaatttttac ttagtgaagg
    39061 gtttatcatg catcaatttt ctatttatag taagttgctg ttgaataata cagctaacaa
    39121 tgccatgatt ggtcggctga gggagcataa tcctaataaa ggaaatatta cattactaac
    39181 ggtcacagaa aaacagtttg cacgaatgat ttatttacat ggtgaaagaa ataattgtat
    39241 tgcaaactcc gatgaaagac ttgtatttct tggggaggct tttgatgaat cttaattttt
    39301 ccttactaga tgaaccgatt ccattaagag gcggtacaat tcttgtgctc gaagatgtct
    39361 gtgtattttc aaaaatagtg caatattgtt acaaatatga ggaagattct gaacttaaat
    39421 tttttgatcg caagatgaaa accatcaaag aatcagaaat catgcttgta acagatattt
    39481 taggatttga tgttaactcc tcaaccattt taaaattgat tcatgcagat ttagaatctc
    39541 aatttaatga gaaacccgaa gtgaaatcga tgattgacaa attggttgct acgattacag
    39601 aactgattgt ctttgaatgc ttagaaaatg aattagattt agagtatgat gaaatcacaa
    39661 tcctggaatt gattaagtcc ttaggagtaa aagtagaaac gcaaagtgat actatttttg
    39721 aaaaatgtct agagatactt caaattttca aatatctcac taagaaaaag ttgcttattt
    39781 ttgtcaatag cggagctttt ctaacaaagg atgaagtggc tagtttacaa gagtatatat
    39841 cattgacaaa tttaacagtt ctctttttag aaccacgtga actatatgat tttccgcagt
    39901 atattttaga tgaagattat ttcttaataa ctaaaaatat ggtataatac tcttaataaa
    39961 tgcagtaata caggggcttt tcaagactga agtctagctg agacaaatag tgcgattacg
    40021 aaatttttta gacaaaaata gtctacgagg ttttagagct atgctgtttt gaatggtccc
    40081 aaaacgattg accacaacat ccaacgctta ggttatgttt tagagctatg ctgttttgaa
    40141 tggtcccaaa acaatagagc tagacaaaaa attgagtttg acgttttaga gctatgctgt
    40201 tttgaatggt ctccattcaa cattgccgat gataacttga gaaagagggt taataccagc
    40261 agtcggatac ctttctattc tttctgttaa agcgttttca tgttataata ggcaaaagaa
    40321 gagtagtgtg atggaacaaa cattttttat gattaagcca gatggggtta agcaagggga
    40381 ggtagttgga gaggttttgc ggtggattga acgcctaaga tttacgttta agcgattcga
    40441 gctaagacaa gctagttcga aatacttggc taagcacgac gaggccttgg tgataaacct
    40501 tttgatccta aacttaaagc ttacatgaca agtggtcctg ttttaattga gacacttctt
    40561 ggggactaag gtggttttgt ctttttgaac catgatgaga gtaaccaatc ctacggatgc
    40621 tctttgcgga accattcgtg ggaattttgc tcaggctctt agtgatgatt gggaaatttt
    40681 tagtatggtg catgggtctc atttaagcga ctctgctagg cgtgagattg tcctttggtc
    40741 tcatcaaagt aatctcggta gctccgctat tctcttgcaa gataatccg
//
LOCUS       DAUGUF010000017        37877 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUGUF010000017 DAUGUF010000000
VERSION     DAUGUF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37877
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.017"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            147..1343
                     /gene="tuf"
                     /locus_tag="VIB71_000866"
     CDS             147..1343
                     /gene="tuf"
                     /locus_tag="VIB71_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEQ8822613.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            1584..2342
                     /locus_tag="VIB71_000867"
     CDS             1584..2342
                     /locus_tag="VIB71_000867"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEQ8822614.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(2441..3676)
                     /locus_tag="VIB71_000868"
     CDS             complement(2441..3676)
                     /locus_tag="VIB71_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8822615.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKKGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(3663..4889)
                     /locus_tag="VIB71_000869"
     CDS             complement(3663..4889)
                     /locus_tag="VIB71_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEQ8822616.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKNNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTVGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLATGQTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     KTAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(4889..5698)
                     /gene="yidA"
                     /locus_tag="VIB71_000870"
     CDS             complement(4889..5698)
                     /gene="yidA"
                     /locus_tag="VIB71_000870"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEQ8822617.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGIHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(6154..7455)
                     /locus_tag="VIB71_000871"
     CDS             complement(6154..7455)
                     /locus_tag="VIB71_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ8822618.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSQGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            7538..7924
                     /locus_tag="VIB71_000872"
     CDS             7538..7924
                     /locus_tag="VIB71_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEQ8822619.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            8154..10835
                     /locus_tag="VIB71_000873"
     CDS             8154..10835
                     /locus_tag="VIB71_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEQ8822620.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLACIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVGMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(10919..11914)
                     /locus_tag="VIB71_000874"
     CDS             complement(10919..11914)
                     /locus_tag="VIB71_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8822621.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGKFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(11978..13885)
                     /locus_tag="VIB71_000875"
     CDS             complement(11978..13885)
                     /locus_tag="VIB71_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEQ8822622.1"
                     /translation="MSLAFARFKETVNPDFCRNYLLDYQTDSYADQKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFDALTKQEERLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYFGSNLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHIFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSICLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHIYF
                     IDGSYQTQFSDRNNYQHDRQILILPPGIFLIIDTIQAQGNHCLVSQFILDNHLEVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNGHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(13972..14793)
                     /locus_tag="VIB71_000876"
     CDS             complement(13972..14793)
                     /locus_tag="VIB71_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8822623.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVLLTVLIGIIGSWLGILA"
     gene            complement(14780..15562)
                     /locus_tag="VIB71_000877"
     CDS             complement(14780..15562)
                     /locus_tag="VIB71_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8822624.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVVIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFAFIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(15581..16069)
                     /locus_tag="VIB71_000878"
     CDS             complement(15581..16069)
                     /locus_tag="VIB71_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8822625.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQNIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(16105..17304)
                     /locus_tag="VIB71_000879"
     CDS             complement(16105..17304)
                     /locus_tag="VIB71_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEQ8822626.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPEAREAALKAADKLVQRYQDKGGFIQ
                     AWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFRDGSGQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKNLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(17304..17741)
                     /locus_tag="VIB71_000880"
     CDS             complement(17304..17741)
                     /locus_tag="VIB71_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8822627.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTAEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGATDDELGGI"
     gene            18066..18860
                     /locus_tag="VIB71_000881"
     CDS             18066..18860
                     /locus_tag="VIB71_000881"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEQ8822628.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKVVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            18885..19526
                     /locus_tag="VIB71_000882"
     CDS             18885..19526
                     /locus_tag="VIB71_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ8822629.1"
                     /translation="MKIALINENSQAAKNGIIYDALTSVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVAYLKSVLEQ"
     gene            19555..20556
                     /locus_tag="VIB71_000883"
     CDS             19555..20556
                     /locus_tag="VIB71_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ8822630.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMTLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGIRHFHFSGISLALGKKTQDLIEILAREAKKRDI
                     CISFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTTI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLHNQRDVQR"
     gene            20561..21196
                     /locus_tag="VIB71_000884"
     CDS             20561..21196
                     /locus_tag="VIB71_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ8822631.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGMSFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            21493..22143
                     /locus_tag="VIB71_000885"
     CDS             21493..22143
                     /locus_tag="VIB71_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEQ8822632.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            22840..23964
                     /gene="queG"
                     /locus_tag="VIB71_000886"
     CDS             22840..23964
                     /gene="queG"
                     /locus_tag="VIB71_000886"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEQ8822633.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRISPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGFDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCIDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNPPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSQKELELIRHKWQF"
     gene            24033..25131
                     /gene="prfB"
                     /locus_tag="VIB71_000887"
     CDS             join(24033..24104,24106..25131)
                     /gene="prfB"
                     /locus_tag="VIB71_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEQ8822634.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            25150..25842
                     /gene="ftsE"
                     /locus_tag="VIB71_000888"
     CDS             25150..25842
                     /gene="ftsE"
                     /locus_tag="VIB71_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEQ8822635.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            25835..26764
                     /locus_tag="VIB71_000889"
     CDS             25835..26764
                     /locus_tag="VIB71_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822636.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(27073..27771)
                     /locus_tag="VIB71_000890"
     CDS             complement(27073..27771)
                     /locus_tag="VIB71_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8822637.1"
                     /translation="MPFIFRYSFFNKVLIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSLGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            27939..28703
                     /locus_tag="VIB71_000891"
     CDS             27939..28703
                     /locus_tag="VIB71_000891"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEQ8822638.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLAGDDSNYITGQTIVVDGGMVFH"
     gene            28811..31312
                     /locus_tag="VIB71_000892"
     CDS             28811..31312
                     /locus_tag="VIB71_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEQ8822639.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLGHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRIQDDKDFTR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRKDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            31647..32840
                     /locus_tag="VIB71_000893"
     CDS             31647..32840
                     /locus_tag="VIB71_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ8822640.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGHDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            32861..34207
                     /gene="asnS"
                     /locus_tag="VIB71_000894"
     CDS             32861..34207
                     /gene="asnS"
                     /locus_tag="VIB71_000894"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEQ8822641.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVTNKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            34622..35512
                     /gene="rapZ"
                     /locus_tag="VIB71_000895"
     CDS             34622..35512
                     /gene="rapZ"
                     /locus_tag="VIB71_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEQ8822642.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQPSFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            35509..36486
                     /locus_tag="VIB71_000896"
     CDS             35509..36486
                     /locus_tag="VIB71_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEQ8822643.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYPGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            36483..37394
                     /gene="whiA"
                     /locus_tag="VIB71_000897"
     CDS             36483..37394
                     /gene="whiA"
                     /locus_tag="VIB71_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ8822644.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYVQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            complement(37571..>37877)
                     /locus_tag="VIB71_000898"
     CDS             complement(37571..>37877)
                     /locus_tag="VIB71_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEQ8822645.1"
                     /translation="LKKEIEIIDKKINRLNDLYINDLIDLPKLKKDIEELNHLKDDYN
                     KAIKLNYLDKKNEDSLGMLMDNIDIRKSSYDVQSRIVKQLIDRVEVTMDNIDIIFKF"
BASE COUNT        11434 a         6726 c         8060 g        11657 t
ORIGIN      
        1 tttcttctat ttaaaaaata aagaaatagc aaaaaacata aaatacttgc attttcattg
       61 taatttgcta caatagtaag gtaaagttag actgtatggc ctaccgtcta tctataaaat
      121 atattttatt ggaggctttt cctaaaatgg caaaagaaaa atacgatcgt agtaaacccc
      181 acgttaacat tggtacaatc ggacacgttg accatggtaa aactacttta acagctgcaa
      241 tcacaactgt attggcacgt cgcttgcctt catcagttaa ccaaccaaaa gattacgctt
      301 ctatcgatgc tgctccagaa gaacgcgaac gcggaatcac tatcaacact gcacacgttg
      361 agtacgaaac tgcaactcgt cactatgcgc acatcgacgc tccaggacac gcggactacg
      421 ttaaaaacat gatcactggt gccgctcaaa tggacggagc tatccttgta gttgcttcaa
      481 cagatggacc aatgccacaa acgcgtgagc acatccttct ttcacgtcag gttggtgtta
      541 aacaccttat cgtgttcatg aacaaagttg accttgttga tgacgaagag ttgcttgaat
      601 tagttgagat ggaaattcgt gaccttcttt cagaatacga tttcccaggt gatgaccttc
      661 ccgttatcca aggttcagct cttaaagctc ttgaaggcga cactaaattt gaagacatca
      721 tcatggaatt gatggatact gttgattcat acattccaga accagaacgc gacactgaca
      781 aaccattgct tcttccagtc gaagacgtat tctcaattac aggtcgtggt acagttgctt
      841 caggacgtat cgaccgtggt actgttcgtg tcaacgacga aatcgaaatc gttggtatca
      901 aagaagaaac taaaaaagct gttgttactg gtgttgaaat gttccgtaaa caacttgacg
      961 aaggtcttgc aggagacaac gtaggtatcc ttcttcgtgg tgttcaacgt gacgaaatcg
     1021 aacgtggtca agttattgct aaaccaggtt caatcaaccc acacactaaa ttcaaaggtg
     1081 aagtatatat cctttctaaa gacgaaggtg gacgtcacac tccattcttc aacaactacc
     1141 gtccacaatt ctacttccgt acaactgacg taacaggttc aatcgaactt ccagcaggta
     1201 cagaaatggt tatgcctggt gataacgtga caatcaacgt tgagttgatc cacccaatcg
     1261 ccgtagaaca aggtactact ttctcaattc gtgaaggtgg acgtactgtt ggttcaggta
     1321 tcgtttcaga aatcgaagct taattttaat taagttccca gaatagcaat ttaagtcaga
     1381 caacttaagt ttgaagaagt ccccaattcg ggggcttttt gctatcttaa actccataaa
     1441 atactgataa ataagaatga aaagctttca gaaaaagagt ttttatttgt gaaaatattc
     1501 ctaaaatata agcaattcct tttaatcgtc ggtcatttgt gctaaaatag aagatataaa
     1561 taaaaaaaga agaggtatgt gatatgtcac gtaaaccaat tattgctggt aactggaaaa
     1621 tgaacaaaaa ccctcaagaa gcaaaagcat tcgttgaggc tgtagcaagc aaattacctt
     1681 caactgacct tgttgatgtt gccgtagcag ccccagctgt tgatttggta accactattg
     1741 aagctgctaa agattcagtt cttaaagttg ctgcacaaaa ctgctacttt gaaaacacag
     1801 gggcattcac tggtgaaaca tcaccaaaag tgcttgctga aatgggagct gactatgttg
     1861 tgattggtca ctcagaacgc cgtgattact tccatgaaac agatgaagac attaataaaa
     1921 aagccaaagc aatctttgct aacggtttaa ctccaattgt ttgttgtggt gagtctcttg
     1981 aaacttatga agctggtaaa gccgttgagt ttgtaggtgc gcaagtttca gcagcacttg
     2041 caggtctttc agcagagcaa gtagcttcac ttgttttagc ttatgagcca atctgggcta
     2101 tcggtactgg taaatcagct actcaagatg atgctcaaaa catgtgtaaa gctgttcgtg
     2161 atgtggtagc agcagacttt gggcaagaag ttgctgataa agttcgcgtt caatacggtg
     2221 gttctgtaaa acctgaaaac gttaaagatt acatggcttg tccagatgtt gacggtgccc
     2281 ttgtaggtgg tgcatcactt gaagctgata gcttccttgc tttgcttgat ttccttaact
     2341 aagtcatcta aaaaagaaaa ggttaaatcc ttttcttttt tagatgactt aactcttact
     2401 ataagagaat aaaggtgatt ctacaggcaa atgcattagc ctaatagcgg tttaatagct
     2461 tttttgccaa tctaatgaaa tgatatttga ttggaaatgg ataacatcta aatgtccctg
     2521 gtttttgcaa aataaaacca ttgaaattct gtttaaagcg caagacaccg tctgaaccat
     2581 caaactttcc agtaatacca agaaaattat attgtttgat gcccttgtga attgccttga
     2641 gcatagcatg ctcttgtaat agagctgggc tataaaattt attaaatttg gggtaagatc
     2701 ctgaaaagag gtagacggcc tcttgttcgg tatagataaa aagacttccc gcaaggaaca
     2761 catctttagt tccatactct tcaagaaaat ggagagcttc agaaattctt acctgaaagg
     2821 tttcgaattg gctggatagt tcttttaatc tattttgctt tttttcagaa tgaggatttt
     2881 tgccaaggtc tcctttaact ttgttgatgc tggttgctag ttgtagttgt ctttgtttaa
     2941 ggttattaag gtaatcttca aaattaagag tcgcaaccat aaattcacaa gagtctccaa
     3001 aactatcata aaagtcctga tagtaagata atgatttgtc aaggtaatct ctacgatcag
     3061 aggttgcttc agtgatttct ttgaaatggt gtaactcatc tcgtttcagt tgacgtaatt
     3121 taataccaaa agtattagct ttttttatta aagcttttcc ttttttgctg aaggaatggg
     3181 ttaaacgtga ggaatcaatt ccttctaact ttttaacgta atgccaaaca ggttcaccct
     3241 caggatagcc tgtttttaaa ccgtcatgtt tatatcctaa cgccgttaaa aggctaataa
     3301 ggtcagtgtt tggatgagaa atagggatgc catcagtatc aaatgactga taattgtcgt
     3361 aaggttttaa aatgagttcg ataacgtctt tttgtttggc atagtcttta agttgagtgt
     3421 aaaaatgttc taattcttcg ggatgattgg tattagggcc tgcattgagt tccatacgcc
     3481 aacctccagc cactttttgg ctaaagacca tagcagcaac ctttagttca ccatcttttt
     3541 caagtccaag aaattgtggt tttgcccctt ttttagccat caagctggcc atttctgagg
     3601 tttggataaa ggaatgatgg acgagactgt ggcagtaatg gtcaaattgt tcttgtgaaa
     3661 tttcaattag tgccattagt tgtgctcctt aatttttttc ttaagttata ggtcaagatg
     3721 gctaagcttg aaacaaggcc gacaggaatg ttgaattcac ctgcaaattc ttcgatggtg
     3781 gggttgagtc tagctttgaa atgatagagt ccaccatctt gttgattttc cacacctcct
     3841 aaattatgcc agcggcagcc tcttttaaaa gcttctttag ccgttttata ccaggttaaa
     3901 agaggagctt gataattgcg ataatcatcg tccattcccg cataaagatt ttcagaagtc
     3961 tcgccataaa tcaaggttag ggtggcggct agtgggatgc gggtttggcc tgtagcgagc
     4021 tgctcgctta aaatggttaa atctttttgt agccgtgcaa tggttttttg attttctgct
     4081 actttgctag gtttactctt atctgttaat cgtgcttgtt ctgctaaggc tttgtccaac
     4141 tgttggatca agagtttttt ttgttcaggt aagtctaaac tagccatagt aatgtaggac
     4201 tgaccagcat aaatatctag taatttttga tagtaggatt tgcctcgaag gataatgcct
     4261 tttcgattct cggttttttt catcaaggct gaaaagtcgt ctagcaattc actgccacca
     4321 atcgtgacat taacaccttt attggtagcg gtacgaatgg attgcttggc ttttttaggc
     4381 aggctgtcaa agtcaaaatc cttggcgtag atgttggctt gtattcttgg ttgaatagtg
     4441 tcttcgagtt cttttgttct gccagaccat tcgacaccaa gtttttttag aaaagcaata
     4501 atagagagtg tcacatcatt ttctttgctc tcttttcctt ctaaagtttg tttgatgact
     4561 aaacttggat caattttgac aaaaagcgct cgtttgcttt ttccgacagt tttgagcgtt
     4621 ttaataacga aatcaaggag ttcaaaattg gcgtagtcca tgattggccc acgtgggata
     4681 taaatcatag tgaaaccaag aggaagtttt ctgattaaac aagcagcagc agcaacttgt
     4741 accccatttt cataaaagct gatgcgttcg tgtttccagt tatttttgac ttttccccac
     4801 tttgaacttt gaagtaagcc agcttgtggc tgtgctaaga caaactgatc atgttcttca
     4861 ggagatattc cgattttata tgtatacatt agtttaatac ccacttgcga atagcatgtg
     4921 ccacaccact gtcattgttg gatttggtga tgtatttggc tatttttttc aattcaggaa
     4981 ccccattttc catgacaaca gggttggcaa cgacttctaa catagcacga tcattttcag
     5041 catccccgat ggccatggtt tgtgacatat ctagcccgag ttttttagct aagtgtttga
     5101 tggcattacc cttgctgacg gtttttggca tgaactctaa ataaaaaggg gttgacttga
     5161 cgatggtgta cttatcaaag aaatgttgag gaatttgctt gatggccgcg tccaaaaggt
     5221 caggttcatc aatcatcatc attttgatga tttctttatt ggtcatttct tcgggagtgc
     5281 gatagaaaat aggcatgttt accaaagtcg attcatgaac tgtgtatttt ccaatattcc
     5341 gattggcagt gtaaatacct tctttggtaa tggcatgcat gtgaattcct aattttcggc
     5401 tcaaaaattc cgtttccaga taatcgtcgt aagtcatcaa ttctttaaca atttcttcgc
     5461 cggtctcggc atcttgcacc aagccaccat taaaagtgat aacgtggttt cctttgtggt
     5521 tgagttctaa ttgttcgagt aatgaaatca ctccggcaat aggtctgcca gtagcaatca
     5581 ccacatgaac cccttgggct ttagcctctt ggacagcttg aaaaacatca tctgtaattc
     5641 gacggtcatc agtgagtaat gtgccatcaa tatcgacagc aaccagtttg atagacatgg
     5701 catcctcctt gtttttttgt ggtttatctt aaaaatgttc tccctcctat cttactaaaa
     5761 ataggtgctt ttgtcatggg atgggaaagg aaacttaagg aaaaacgaga gaaaacgttt
     5821 tagtttagct caatcgcctc tgtagtaact aaaaagattg aagaaagtac tctttcttca
     5881 atcttagaat ggagacaaac ccagtttgat gctcaaaaag catgaactgc tctgctgatt
     5941 tgacaactga tttcttattt ctgcgtgtga cgtgagccaa aacagctgct ttttgctgtg
     6001 gcaaaagtgg tgtcaatact ggcagtgacg ttacgcggaa tttttgagac cctaggctca
     6061 aaaataaagc atagaattcc aaaggaagtc gctgccataa gcatcaccta agaaaagtat
     6121 caaaaaagac tttttctgca atcttaaagg gctttactga ctaaagtgaa aatgcccatt
     6181 ggaaatataa ctcataaaag tttccttgct aggagcaaag aggtcatcga gctctaacat
     6241 ttcctttgga aaataaaagc gacggtctcc gtaggttgtc cctgttaatg ctttgacaat
     6301 aggagataac tgagataatt cagcaaggct cccgtctttt tgtatcattt caatctgagt
     6361 tcttggattt tcgagctctg gtcgataaat atcataaggc aggtcgaagt tgatatggat
     6421 accggtgtaa taatctggat caaagccaac tgattcgacc aattggcgca agcgttctaa
     6481 ctctccttgg gaatcttggt caaaggtaac agacttcaga atttttcgat taataaagcg
     6541 actggccaaa tctgataaga tatggtcttc gcttgccatc cagacttgga agtaagtatt
     6601 catgaccccg tcatctaggg ctatataatc tgctaaatta gccttctttt caaagaaggg
     6661 gatgagtcca ggagctgttt tttggaaata agcctgttgc tcaggatata agtgttgggc
     6721 tcttttgagg agattttgta agatgagctc aacagcacgg ctggcgggat gaaaatagac
     6781 ctgcatgtac atttgaaaac gactgacaat atagtcctcg acagcatgca taccactatg
     6841 ttcaaagaca atgccatctt caacaggtcg aatcacacgt aggatgcgca ttaaatcaaa
     6901 ctgaccgtaa ttggcagcag aaaaataaga atctcttaaa aggtaatcca tacggtcgca
     6961 gtcaatctgg ctggaaatca gttgcacaac ttgcttgtta ggataagtat gattaatcac
     7021 gctggcaact ttgtctggaa aatcaggagc atgacgcacc aaaatggcat tgatttctgt
     7081 ctcaggattg gtaattatct cctgagtaaa ggcctcgtga tccgtatgga aaagggcctc
     7141 aaaggtatga gaataggctc catgaccaat gtcatgtaag agggcagccg tcatagtgac
     7201 cagactttca tctttattcc agatatcagc gtatttctct tcaaaaatag ctgtcacccg
     7261 acgggcaatt tcgtaaacac ctaggcagtg agaaaaacgg ctatgttctg cgccgtggaa
     7321 ggtgaaagct gttgtaggga cttgtttgat gcgtcgtaag cgttggaatt ctttggtatt
     7381 gataaggtca taaattaatg gattatcaat gtggatatag ttgtgaacag ggtcacgaaa
     7441 tactttttca ttcataattt ttattatatc aaaaattgat aaaataagga gaaattgata
     7501 gaataaacag acgagcttag aaatagaaag aagagttatg aaattacagt taaccaacca
     7561 tattcgcttt ggagatgaga cagagattat tcaagaaatt catgattgtg agtggcgaga
     7621 aaaagggggc tatcagtacc tcatctatca aaacactgac aaggaaaagg ttgtcatcaa
     7681 gtataatgag acagaactga ccatgagccg tttttccaac cctcagtcaa tcatgaaatt
     7741 ttttgcgggc aagaaggtcc tgattgctct acctacaccg atgggggttc aacaattttt
     7801 gacagatacc agtcattacc acttagattg ttcttgtcaa aaattggacc ttcattatca
     7861 tttgcttcaa gctcaaacag aaatgctatt tgcaagctat catcttgagc tgagttggga
     7921 ttaactaaaa agatagcagt aaatcatctg attagggatt attcttgttt tttagtcagg
     7981 tttttactat aatggttatt atatcaaggg agtagcagac ggctagccgt gattgtatcg
     8041 tcaatacgga atttcggttt ccggtacaat cttaaacagc gagacttgtt taagaaaata
     8101 aacaggtctt tttatttgaa caactaaaat aaaaagacca aggaggtact aatttgtcta
     8161 aagaacaaag acatgaagca ttttacacgc aaagtgaaga gaccgtactg gctcaattag
     8221 agaccagtcg cgaaggtctt acgtctgccc aagcaaaaga gcgcttagca gagtatggtc
     8281 gtaatgagct tgatgaaggc gaaaaacgaa gtttatttat gaaattcctt gatcaattta
     8341 aggatttgat gattattatt ttgattgtgg cagcccttct ttcagttctt acagagggga
     8401 tggaaggttt gacagatgcc attattatct tggctgttgt tatcctaaat gctgcttttg
     8461 gtgtttacca agaaggacaa gctgaagctg ctattgaagc cttgaaatca atgtcaagtc
     8521 cactggcttg tattcgccgt gatgggcatg tgactgagat agactctaaa gaattggtcc
     8581 ctggagatat tgtcttgcta gaagcgggag atgttgtccc tgctgatctg cgtcttttgg
     8641 aagctaactc cttaaaaatc gaagaagcag cgcttactgg agaatctgta ccggttgaaa
     8701 aagacttgtc aacggctgtt tcagaagatg ccggtattgg tgatcgcgtc aatatgggat
     8761 atcaaaactc aaatgtgaca tatggtcgtg ggattggggt tatcactaac actggcatgt
     8821 acaccgaggt tgggcatatt gctggtatgc ttgctaatgc tgatgagaca gatacaccat
     8881 tgaagcaaaa ccttgacaac ctttctaaga ttttgactta tgcgatcctt gtgattgcag
     8941 cggtgacttt tgctgttgga gtcttcttgc gtggtcaaca cccgcttgaa ggcttgatga
     9001 cttcagtagc gcttgccgtt gcagctattc cagagggact tcctgcgatt gttactgttg
     9061 tgctttctct tggaactcaa gtacttgcta aacgtaacgc cattatccgt aaattaccag
     9121 ctgttgaaac gctaggatca actgaaatca ttgcttctga taaaacgggt accttgacaa
     9181 tgaatcaaat gaccgttgaa aaagtttata ccaacgggac actccaaagt tcatcagctg
     9241 atattgcttt tgacaatacg acacttcgtg taatgaactt tgctaatgat actaaagttg
     9301 atccttcagg gaagttaatt ggtgacccaa cagaaacagc tttggtacag tttgggttag
     9361 accacaattt tgacgtacgt gaggctatgg tggcagaacc tcgtgtggca gaattaccat
     9421 ttgattctga ccgtaagttg atgtcaacca ttcataaaca agctgatggc aaatatttca
     9481 tcgctgttaa aggtgcgcca gaccaattgt tgaagcgtgt cacacagatt gaagaaaatg
     9541 gacaaattcg tcctattacg gatgctgata aaaaaaccat tcttgatacc aataagagtc
     9601 ttgccaaaca agctcttcgt gtcttgatga tggcttacaa atattctgat gctcttccaa
     9661 cactggaaac agaaattgtt gaggctaatc ttgtcttctc tggtttggta gggatgattg
     9721 accctgaacg tcctgaagca gcacaggctg ttaaagtagc taaggaagct ggcattcgtc
     9781 caatcatgat tactggtgac caccaagata cagcaaaagc tattgcgaaa cgtcttggta
     9841 ttatcgaaga agatggcgtt gatcatgtct ttacaggtgc tgaactcaac gaattatcag
     9901 atgaagagtt ccaaaaagtc tttaaacaat actccgtgta tgcccgtgta tctcctgagc
     9961 ataaagttcg tatcgttaag gcttggcaaa atgaaggcaa agttgttggc atgactggcg
    10021 atggggttaa cgatgcacca tctcttaaaa cggcagatat tggtattggt atgggaatta
    10081 caggtacaga ggtttctaag ggagcttctg acatggttct tgccgatgat aactttgcaa
    10141 ccattatcgt tgcggttgaa gaaggacgta aggtcttctc aaatattcaa aaaacaattc
    10201 aatacttact ttctgctaac atggcagaag tctttaccat cttccttgca accttgtttg
    10261 gttgggatgt gcttcaacca gttcacttgc tttggattaa cttggtaact gataccctac
    10321 cagctattgc tcttggtgtt gaacctgctg agcctggtgt gatgaaacac aaacctcgtg
    10381 gacgtaagtc aagcttcttt gatggtgggg tgaaggaagc cattctttac caaggtgcct
    10441 tccaaaccat tttggtgctt ggggtttatg gttttgcctt gatgttccca gaacacacaa
    10501 gctaccatga tgtccatgca gatgctttga ccatggctta tgtgaccctc ggtttgattc
    10561 agttggtaca tgcctacaac gtgaaatctg tttaccaatc catctttact gttgggttgt
    10621 tcaaaaacaa attgttcaac tattctattc cagtggcctt tgtagcattg atggcaacag
    10681 ttgttgttcc tggatttaat caattcttcc atgtgacaca cttgacgatc acacaatggt
    10741 tagtggttat tatcggaagt ctcttgatgg ttgttcttgt tgaattggtg aaagctgttc
    10801 aacgatcact tggtcaagat gaaaaagcaa tttaatagac gctaaaaggt ttgagacaat
    10861 tgtctcaaac ctttttttat aatcgttaca acgataagga ctattggtat gcctgacatt
    10921 aaaaagttga ttcttgccaa ttgacttgac agtcaaaaat ttgttgtttg gcttcttgac
    10981 tgtgaccttc aatatcatcg attaaaatct tagtagcctg ttcgccttct tcataggcgg
    11041 gttggataat agttgttagt gttggtgaag aaaattttgt ccactcaatg ttatcaaatc
    11101 ctactagtcc aatctctggt atattaaatt taagagactt catagctgta aatacttttg
    11161 gaagagccca acaattgggg acaaaaacca aactcttttt agtcagtgat ccttgcaaaa
    11221 actgagcaat tgcctctgaa gaagtctgat tttcatcaat aatcatttct tgatgagtaa
    11281 gatgattagc ttctaacaca tcaatgaagc ctgaagcgcg ttcaatacga gtgctaagta
    11341 aattggggtt acccgtgatc atgataaaat gttcataacc tttatcgata cattgttgaa
    11401 tggtatcata aacagcatca taattattag ttttgaccca gttggtacga tgctcataaa
    11461 gttgactatc aaaaaagaca accttctttt ttttaatatc gataatgcga gaatacttcc
    11521 tgaaattaga ggtaggttga atgataaagc catccactcc gaggttcagc atcttttcaa
    11581 tgagttcatc ttcgcgagaa gggtcgtagt tgctgtttcc gatgataatt tggtaaccaa
    11641 attcctgggc tttgctttca attcccttaa caatttgatt ggaaaaacta ttggtaatat
    11701 caccaataac cacgccaatg agtttagtag atttggcgtt tagacttctg gcagcaatgc
    11761 ttggtttata gttggtagct tcaatcgtgc ttttaatgcg atttttagtt tcttctgaca
    11821 tcttgtcaaa tttaccgttc aagtaaaagg aaactgtcgt tttggaagtt ttagccaatt
    11881 cagcaatatc tttgatggtt actttgcgct gcattgcata cactccttta atttagtaat
    11941 ggttagtcat attataacat aaggactcgt aaaagattta gtgtttcaat cgaataatct
    12001 cattcgtgat atggttgata acaaccacct ttcctctgat tttatgacca tttaggagaa
    12061 ctagtttttc tcctttaatt aaatcctctt ggagaacaca gatactgtag tcaaactgct
    12121 ttccttttaa atgccaggaa agggcggtct caattgggtt gcgtttgcct gtttgaagtg
    12181 gtgttaaggg agtaactttg gtatcgtcag ggactaatag ggtactggtg caacccttgt
    12241 ctttaaaggg ttttcgtttg atgagtttgt gactagtcag gtattggttg tatttttttg
    12301 acaaaatcgt ttcttcgata gtgaaagggc agtcactgat tagtctgagg tcactaaggt
    12361 gatctgtctt tacttctaag tgattatcaa gaataaattg actgacaaga cagtggttgc
    12421 cttgagcctg tatcgtatca atgataagaa aaattcctgg tggtaagatg agaatttgtc
    12481 ggtcatgttg gtagttgttc ctatcagaga attgcgtctg gtagctacca tcaataaagt
    12541 aaatgtgtcc attttgtcga aggtgacaat aattggattt ggggtaagaa aggtaagccc
    12601 aggagctatc aatctgctca ggtaattgtt cttctaagaa ggcggtagaa tgatggctag
    12661 cgctttttag ggcatagcgt aatggttctt ctttgtaagt gtatcgccca gcatcacaga
    12721 aaagtggttg tcctttataa tagagacaga tactattttg gtcgctatgg gtatgggaac
    12781 taccgatggg cccatttttg aaaaaaagat aataattttc ttgattgatg gtaatgtgcc
    12841 cggaatgttc aaagtgatgc gcaaaagttg gtaaggtttg gacgggtaac tgttcaaaaa
    12901 tgtggacacc tttttctcct agaaggagaa gactatcgat atcaagtgtg ggaaaagcag
    12961 cagcttttaa gtgtggttct tcaaggatag tggctgctag tgttagaata tctctggtat
    13021 cggtaaagtc actgtctcct aaggggatct gtttgtggtc agggccagtc attttgagga
    13081 gataatcact catggcaagc aaagtaggtc taagctgtgg aagataatca gggactagag
    13141 cagttaattc cagaagggct ttgagtactt ccacatgata catggttgat tgttcaaatt
    13201 gactgccgtc ttcgagaatt tgtagtgcga tttgttgtgt caattctttt ctagcgaaag
    13261 ctgttgctgc agcaatatca aggttggaac caaagtaggc atcagctaat aaaatcgcag
    13321 tggtttgcaa gattccccaa ttgctgagac tgtatttatc aaggtagttg gcatggagaa
    13381 agtgaagttg tttttccagg gaagctagga tgagcctttc ctcttgcttg gttaaggcgt
    13441 caaaaagatt aaggtaaatc aaacatttga cccaagcaaa acaacggatg ccagtatcta
    13501 aggttctagt agctaacccc ttagggtcta aaggaatagc tgattcaatc caattgagga
    13561 tgaaactttt ggcttttagg agataccgtt catctctttc aacaaggtag acgaggatta
    13621 atgtttggag ataggtctgt cgatttaaca taaaattcca ctcaggatca tctgtgacag
    13681 cctcttgcca agtaatggga tctaagtggt aagggatgtg gcagggctcc atatcccaat
    13741 tatcttcaaa taaaaaggta ttggttaaga gtaggtcagc tattcttttt tgatcagcat
    13801 agctgtcagt ctgatagtct agcaggtaat tcctgcaaaa gtctggattg actgtttctt
    13861 taaagcgtgc gaaagcaaga gacataggac gtttcctttc caaaagaaaa gagacctcat
    13921 catgtgctta ggaactattt ccctatgctc ataacaggtc tctgtgaacc attaagctaa
    13981 aatacctaac cagctaccga taataccgat aagaacagtg aggagaacca atttgtaggt
    14041 tgtccatttt ttgtttttaa taaggtaata catgagtaag gtaaagagag ctggtaaaag
    14101 tgcaggagca attttatcaa gcattccttg aatagtcaca aatttttgtg ctgtattggc
    14161 cgcatccacc ttgccagcgg caaaagtaat gggaacagtt attttaacag aagtagcagc
    14221 taatccagcg ataacggtaa caccgacaat atttgccatg cgcgacacaa ccgccatttg
    14281 ttcacttaat ttatcaataa agcttgtgcc gaccttgtag ccatagagac cagaaccgat
    14341 tttaatagca gttaggataa tattcatggc taggaagaag aaaattggac ctaaaactaa
    14401 accatcacta gctaaggaag ctgcaatcgt tgaaaagagt ggcgccaagc aaaattgtga
    14461 taaggagtca ccgataccag ctaaaggccc cataagtgcc attttgatgt ttcgggtttc
    14521 ttcttcagga cgatcatttt ctaacatgac caagtgcaga ctggtgatga aaggaaggaa
    14581 gtgagggtta gtattgtaaa actcacagtt atcttctaaa gcttgatata agcccttttt
    14641 atcactgcca aaatgttttt tcaaggcagg atagatgacg ttggcgtatc cgataccttg
    14701 gtaattactg taattaaacc cattttgtag gaagaaagct ctcagagctg ttttgaggta
    14761 atctttcttg gttaatttat tagatccagt catcttgttg gcctccttgg acagttgttg
    14821 catcgacttg tttaggtttg ttgtaaaatt cattcaaggc gaaaatgata ccaataatag
    14881 cgataccaat ggttggaatt tggaggtagg ctgcacaaac ataaccaatc agtacaaaag
    14941 gaatcaattc tttcttggcc ataacagata agatcatggc aaatccgata gcaggtaaca
    15001 ttttaccagc gacagtcaat ccattgagca agacaggtgg gatataatca accaagtgaa
    15061 ggagagtatc cattgacaag gcacctaata aaccaaggcc taatccgata aaagcgaaag
    15121 cccagatagt gccgttggca gcgaatttga agcctctaat attgcctttt tgcaattgct
    15181 ttttagcggt ttcgggagcg ccagcaaaag ctgtataggc gaatgtctga agaaattgga
    15241 tgacaactgc gattggtgtt gataaggcta gggccgcttc tggggtaact ttaccagcac
    15301 tggtaatagc catcaaggta ccaaagatac cagggccgat aggattagga ggaacggtac
    15361 caccggcacc cactccaaat cccatataag ctaattcgga gatagctccc atgctaagtg
    15421 cagttggcaa gtcacctaag ataatcccta caccaaaaga cagaataata caacggttgg
    15481 tgtagatgcc aagtaacatt ccgctgaaac aaaaggctgt ccaaagacca attaaaagtg
    15541 cctgtaacaa attgatatcc atatcaatct cctttattta ttaaatataa tctaagatgt
    15601 caacgtcaga ggcgctattg ccagctggag ttgttttggt gttaaaaacc acgtggtggt
    15661 catgggctaa gcaacgaata gcagacttgt ctgtttctcc cagcgaaata aactgggtaa
    15721 tcgcaacctt atcatcagtt ttatgaatat taccgatatt gatttctgtg atgggaacac
    15781 ccccttcaac taggcgtttg gcatcttgca aatctttgac cacgatgaag atattttgag
    15841 caggacttgc tttatgaatg atgtcaatca ctttttgaat ggagaaaaaa cgaatggcaa
    15901 tactggatgg aataactgtt ttcatgaggg attgttgaat cttatcttca gaaaccgcat
    15961 cgttagcgac gataacggtg ttgcagttga ggaatttgac ccataattgc ccctgtccgt
    16021 gaatcaagcg ctcatcaact cgcgtcatga taatgtttgg ttgtgtcata aaatctcctt
    16081 tttaaatgtg attatcggtg tttgttacca gtaagggttc cagtctttgt agaaacgaag
    16141 cagagcttca aggtagtaat agtctcccca gatatttcct tcatccaccc cttttccaga
    16201 gtgccaagaa tagactccgt gaagcagtag aggagcacca ggcttgagat ttttgttagc
    16261 ataatcctta atcaaggctc ttagcatgct gtgcatggca gcttcatatg tttttttatc
    16321 aggatcatga tctggtaagg tttttaacat ttcatgaata ccacacacag caatggctgt
    16381 tgctgaacta tcacgagact gtccacttcc atctctaaaa attaaatccc agtaggatac
    16441 ctggtcttta ggaagacggt tcaagaaata atgggtcatg cccttgaaga gttgaatgag
    16501 ttcaggttct tttaggaaac gataggtcaa aggaatgcca taaatgcccc aagcttgccc
    16561 tctggcccaa gccgaatcat cgctataacc ttgtcgggtg acccctttaa caggatcccc
    16621 tgtttctgga tcaaagtaga aggtgtggta agcagaggcg tcatctcgga tgacatgatt
    16681 ggctgaggcg tagaaatggt tgatcgccat gtcacggtaa cggttgtctc cagtttcttg
    16741 gctagcaaaa aagagtaatt ggatgtttag gagacaatca atgattaaac ggtaatcttc
    16801 ttttttcccc agttctcccc aggcctgaat aaagccgcct ttgtcttgat agcgttggac
    16861 taatttgtcg gctgctttca aagcagcttc tctagcctca ggtgttttta aaagtttcca
    16921 ctcagccatg caagaagggg tgtaaagaaa gcccaaatca tggtgatcta gctcaatgtc
    16981 tcttgttact cgatctagga aagaaaggtc atttgcttga gccagagctt taatggcatc
    17041 atccccactg tattcgtaag ctaaccaaag gcaacctgtc caaaaggcat tggtccattc
    17101 cgtgttgtcc ataatggcgt attggttatc tttggtagct ggcgttggaa agtcttcttt
    17161 aaaatagtcc atattaagcc gaacttgttt gagggctaag tcaagggcct gagtaatgtc
    17221 ttcttggctt agaaagtctt ctttggtaaa tcgttcaggc tgcttgatag gttcaagagc
    17281 aatggttttt aaagatcgtg tcattaaatg cctcctaact catcgtctgt cgcaccgtct
    17341 tcttgctgag aaagagtttt ccagtcaaca atgccttctt tagaacatgt tataagtcct
    17401 gatactaagt cgtcaaaaga agctgctgtt tgtcttgcaa aactagcttc aatcagcatg
    17461 gctaagttaa ggccagaaag aacattacac gtcgtgtttg gaagagattc cattaaggtt
    17521 gcagcgactt taaaaggggt acctcctaga aggtcacaaa gaactaaggt ttcctcttct
    17581 gggattaaag cacgagataa ttggtcctgc acatcagcgg cggtcatctc agcagtaaaa
    17641 tcaattgcag ttaccttctc ttgtggtcct gcaattaact ctagggatga gacaatccca
    17701 cttgcaaagt gtccatgtcc cataacaata atagcaatca tgataaaact ccttttggtt
    17761 taccggttta ctcaaaaaca ttgtagcgct ttcaaaattc tttgtcaata cttttttgag
    17821 atttattttt agagaaaata gagattaatc tccataacat gtcaaaaggg atcaatcata
    17881 gttgtttaat gaagaacact atgtaaaaga aatgccatta aggaataaaa cctattttta
    17941 aaagctagct agtttctctt ttttattttt gaaccgtttt cataaacatc ttgacaaaac
    18001 tagtttactt tgttatagtc ttagtaaaca ggtttactta atttaataac aaaaaggaga
    18061 atcctatgga aaatatgttt tcgttacaag gtaagattgc cttgattacc ggagcatcct
    18121 acggtattgg ttttgaaatt gccaaagcct atgctcaagc gggtgcaact attgtgttta
    18181 atgacatcaa acaagagtta gttgataagg ggttggctgc ctatcgagag ttagggatag
    18241 aagcgcatgg ctatgtttgt gacgtgactg atgaagctgg tatccaacag atggttagtc
    18301 aaattgaaga tgaagtaggt gttattgata ttctggtcaa caatgcaggt attattagac
    18361 gtacgccgat gcttgaaatg gccgcagaag attttcgtca agtcattgat attgatttaa
    18421 atgcaccttt tattgtgtca aaagtagttt tgccatcgat gattgcaaaa ggacatggta
    18481 aaattataaa tatctgttct atgatgagtg aattgggccg tgaaactgtt agtgcctatg
    18541 cggcggctaa aggtggcttg aaaatgttaa ccaaaaatat agcctctgag tttggagaag
    18601 ccaacattca atgtaatggg attggtcctg gctacattgc aacaccacaa acagctccgt
    18661 tgagagagcg acaagcagat ggtagtcgtc atccttttga tcaatttatc attgctaaaa
    18721 caccagcagc acgttggggg acaacagaag acttagctgg tccagctgtt tttctagcta
    18781 gcgatgccag taattttgtg aacggccata ttctttatgt cgacggtggc attttagctt
    18841 atattggaaa acaaccttaa tcacacacta gaaagagatt ttatatgaaa attgcattaa
    18901 ttaatgaaaa tagccaagcg gctaaaaatg gtattattta cgatgccctt acctcagtga
    18961 cagataaaca cggctaccaa gtttttaact atggcatgta tggcacagaa ggtgaaagcc
    19021 agttgaccta tgttcaaaat ggactcttag cttctatttt attgaccact aaggcggccg
    19081 attttgtggt gactggttgt gggacaggtg ttggagctat gttggccttg aacagcttcc
    19141 caggagttac ctgtggtttt gcgagtgagc caacagaagc atatctcttt tctcaaatca
    19201 atggtggtaa tgccttgtcc attccttttg ccaaaggttt tggttgggga gcagagttga
    19261 atttgacctt aatatttgaa cgcctctttg cagaaccaat gggtggtggt taccctaaag
    19321 agcgagctat tcctgaacag cggaatgcac gtattttaag tgatttgaaa aaaattactt
    19381 acagagattt gttggcaatt gtcaaagaca tcgaccaaga tttcctcaaa gaaacgattt
    19441 ctggcgctca ttttaaagag tacttctttg ccaatgcgga gccgtcagaa ttagtcgctt
    19501 atttgaaatc agtacttgaa cagtaattcc attttgacga ggaaaggagg tcacatgtct
    19561 aagttattat tggttggtga accgctgatt cgcgttagcc ccaatcagtt tcagcctttg
    19621 accaatgcct gcgacgctca gctttttttc ggcggttcag aagttaatat tgcaagaact
    19681 ctaggcggtt ttggcttaga agcaaggcta tttacggctc taccagataa tcctgttggc
    19741 cacgcttttc atcagttttt gaagcaaagc ggtgtggata tgaccttgac ggcttggcaa
    19801 ggtcatcgcg ttgggctata ttaccttgaa aatggctttg gctgtcgggc tagtcaggtt
    19861 tattatgacc gctgtggctc tagcttttcg gctttagata aggacagcct tgatttagct
    19921 gccatttttg aaggcattcg tcactttcat tttagtggaa tcagtttggc gttgggtaaa
    19981 aaaactcagg atttgattga aatacttgcg agagaagcta agaaaaggga tatttgtatt
    20041 tcctttgacc ttaactttag atctagtatg attgccgtag ctgatgctaa acgactcttt
    20101 tctcactttg ctcaatacgc ggatattatt tttggcatgg aacctttgct gttagacagt
    20161 gacgattttg acatgtttga taggaataag gcagatacta cgacgattag agaacgtctg
    20221 gcaggacttt atcagcgcta tcagttacaa gctatttacc atacggagcg ttcaaatgat
    20281 gcccaaggca gtaatcgttt caaggcttat gcctatgatg ggcagtttta cgaatcctgt
    20341 gaagtgacga ccccagtctt gcaacgggtt ggaagtggag atgcttttgt ggcgggttta
    20401 ctttatcagt tgttagaagg taacgaaaag cagcgcaacc ttgattttgc tgtggcaaca
    20461 gctagcctaa aatgtacagt agctgaagat cagctctatc acagcgtcca acaagtagaa
    20521 gcagtcttac ataatcaacg agatgtccag aggtgatgat atgggaaaaa tagaaatctt
    20581 aaccaaactt aaggctaatc ggcttgtcct ggttgtacga ggagagtcta gtgaggaagc
    20641 tttagcttgc agcctggcca gtattgaagg tggcattaag acaattgaag tcacctatac
    20701 taaccccttt gctagtgagg ttatcggtca attagctgaa cgcttcaaag aagatcctga
    20761 ggtattgata ggtgctggga cagttttgga tgatgtcact gcccgccaag ctattttagc
    20821 aggagcacag tttattgttg gtcctaattt caatcgagca gtggctttga tttgtcatcg
    20881 ttatagcata ccttatttac caggttgtat gacggttaat gaagtggtta cagcattaga
    20941 atcaggggtt gatatggtca aaatttttcc tggttctact gtagggatgt cctttattcg
    21001 ggcaatcaaa tctcctttgc cacaagtaga ggttatggtt acaggcggag tttcttcaga
    21061 taatctcaaa gactggctag ctgctggagt agatgtttta ggcataggag gcgagtttaa
    21121 tcagttagcg agccaaaaac aatataacct aatcactaag aaagccgctc attatatcaa
    21181 aagtttgcga caataatcta aaaaacgttt ttaccttggc tttagtgcta gtaaaaacgc
    21241 ttttttatca ttcattcaat taatatgctt ctgcttatgt ttttccagat agtatagata
    21301 taagagcagc taatttaaca agatgagcct gtcgtttgat atataggata taaacttttt
    21361 atgatcaaac aaaagtaata ccttttgaat tcgttagtat tgacctgatc taaagtgata
    21421 tcacttagaa tgaactagct gtgcagcttt tacagcaact tatgctaaaa tagaaaaaaa
    21481 ggagaaatgt tgatgattaa aggaattatt tttgatatgg acggtgtttt atttgataca
    21541 gaaccttttt atctgaggcg acgagaagat ttttttaaga caaagggaat tcccattgat
    21601 catttgaact ctaaagattt tattgggggc aatctccaag aattatggaa agagttgtta
    21661 ggtaaaaata gggatgatgc tatcgttaag gcaattacaa ctgactatga cgcttacaaa
    21721 caagcgcata agcctcctta tcaaaaactg ttgattacag aagtgaactc ttgtcttgaa
    21781 cagttgaaaa aacaaggtat taaactggct gtggcatcaa actcgaagcg tcaggatgtt
    21841 ttgttggcgt tggagacaac gcaaataaaa gattattttg aaataatcct agcgcgtgaa
    21901 gatgtttcta gaggcaaacc ttatccagat atctataata aagcagtaca aaaactagga
    21961 ttacaaaaaa aacaactgct tgtagtagaa gacagccaaa aaggcattgc tgccgccaaa
    22021 gcagccaatc tgacagtttt tgccattacc gactaccgat atggcattga tcagagtcaa
    22081 gctgatcaca agatagatca tttaggacaa ctgtgtgtaa aaatcggttg ttttggatcg
    22141 tgaagtaacg caactaactg atcattgatg atacttcaag acacttaaga atacgtctag
    22201 gactttctac agaccaataa caagaatacg tttatgtgtt tttactgttt ttttagctac
    22261 ctatttacaa tatgacactg aaaagagtac tatgtttaag ttattatcaa aaaaaccgtc
    22321 gcataagatc acctagaaaa ggattatgat ttttgtgatt tggatgcgat tgttagtcgt
    22381 tgaccatctt tatgtggcag gagatatgtt taaccgtggt cattatttgg atttgttttt
    22441 agattggcta gtgagtaaat atagaaggat cataatactg ctttgacaaa ggcagtatct
    22501 gagtccatga gttgcacgga taatgtgact cggttttggt tagctataat aatatttgga
    22561 agtgttatgc tgcttgtctt cgtaggtcca ttgattatag tcagacttac tttagagctg
    22621 agctgactgt ctagacaaga cgtgatggag atgtgatttc tgaccaagta gaggtaacca
    22681 gaaaagggac ttttacgatg taattgaatt tacttgttgc attcttgtgc atgttaagag
    22741 agaaaaccca gataaatcag gaagtaaaat ggttatgttt gattagaatt gtccttcttt
    22801 ttccttgaag tcttaactta ttttgattat gatagtagta tgactattaa ggcagaaatt
    22861 aaggcactcg ccaaagaaat tggtatctct aaaattggtt ttacgacggc agataacttt
    22921 gattatttgg aaaagtcatt gcgtgcttct gtggaagagg ggcgcaattc aggatttgaa
    22981 cataaagtca tagaggatcg tatctcccct gaaaggcttt tagaatcggc taaaacgatt
    23041 atttcaattg gcgttgctta tcctcacaaa cttcctcagc aacctcaaaa aacaccttat
    23101 aaacgtggca aaattacacc tagttcgtgg gggtttgatt atcattatgt ggtcggcgaa
    23161 aagttagaca gactatcaaa aggcattgaa gagctgtgtc gagattttcc tttgcaacaa
    23221 aaagcaatgg tcgatactgg agctttagtt gatactgcag ttgcccaaag agcgggtatt
    23281 ggttttatag gaaaaaatgg tctagttatt tctaaagaat atggctctta tatgtttttg
    23341 ggagaattaa ttaccaattt agagatcgag ccagacaagc ctgtcgatta tgattgtggt
    23401 gactgtcgtc gttgtataga tgcctgtcca acttcttgtt taattggtga tggctcaatg
    23461 aatgccaagc gttgtctatc atttcaaacc caagataagg gaatgatgga catagagttt
    23521 cgaaaaaaga ttaaaacagt tatctatggt tgtgatattt gccaaatttg ctgtccttat
    23581 aacaaaggta taaataatcc accagctaca gagattgatc ctgagttggc tcaaccagaa
    23641 ttaataccat ttttgagttt atcaaatgga caatttaaag aaaaatttgg tatgattgct
    23701 ggaagttggc gaggtaaaaa tattttacag cgtaatgcca ttattgcgct agcaaatgct
    23761 catgataaaa ccgcagtggt caaattaata gagattattg ataaaaataa taaccctatt
    23821 catactgcaa cagctatatg ggcattggga gaaattgtca aaaaaccaaa cgatgagata
    23881 ctggcgttta tgagtcattt aaccttaaaa gatgaagata gccaaaaaga gttggaatta
    23941 atccgtcata aatggcaatt ttaagccttt tatggtattt ttaagaacct tatgataaaa
    24001 taaaacagat taacaaagat tggagaaatc tcatggaagt ggctgaaatt cgccaaaaaa
    24061 tagtagaaaa taaagagaag ttgactagct tcaggaggtc tctttgactt agatcgtttg
    24121 gaagaggaga ttgctcttct tgaaaatcac atgactgagc cagacttttg gaatgacaat
    24181 attgcagcgc aaaagacatc tcaagaacta aatgaattaa aaggtaagta tgatactttc
    24241 cataatatgc aagaattatc tgacgaaaca gaactcttac ttgagatgct tgacgaagat
    24301 gattctttga aagaagaatt agaagaaaat ctaatgcagc tagataagat aatgggtgct
    24361 tatgaaatga cgcttctctt atctgaaccc tatgaccaca ataatgctat cttagaaatc
    24421 catcctggtt caggaggaac tgaagcgcaa gattggggag atttactctt acgaatgtat
    24481 acccgttttg gcaatgctaa tggtttcaaa gtagaagtat tggattatca agcaggggat
    24541 gaagctggta ttaaatcggt taccctctct tttgaaggtc ccaatgctta tggtttgttg
    24601 aaatcagaaa tgggagttca tcgcctcgtt cgtatatcac cttttgattc ggctaaacgt
    24661 cgtcatacct catttgcttc agttgaagtg atgccagagt tagatgatac gattgaagta
    24721 gaagtacgtg atgatgacat taaaatggat actttccgtt caggaggagc tggtggtcag
    24781 aatgtcaata aagtatcaac aggtgttcgt ttgacgcata ttccaactgg aattgtggta
    24841 tcgtctaccg ttgaccgtac tcaatatgga aaccgcgatc gcgctatgaa gatgttgcag
    24901 gctaagctat atcagttaga acaagaaaag aaagcacaag aagtagatgc tctcaagggt
    24961 gataaaaaag aaatcacttg gggaagtcag attcgttctt atgttttcac cccttatacg
    25021 atggtgaagg atcatcgtac taactttgag cttgctcagg tagataaggt tatggatgga
    25081 gaaatcaatg gctttattga tgcctacctt aagtggcgca ttgaagacta aaaataataa
    25141 aggagaaaca tggcactaat agaaatgtct ggtgttacta aaaaataccg ccgctcaacg
    25201 accgccctca gagacgtcaa tgtttctgtt aaccaaggtg agtttgttta tctcgtaggc
    25261 ccatcaggtg ctggtaaatc aacttttatc aaactccttt accgtgaaga acaactgaca
    25321 actggtaagc tatatgtggg tgaattcaat ttaactaaac taaaagcacg tgatgttccg
    25381 attcttcgtc gtcacatcgg agtagttttt caagattaca aactgctacc aagaaaaaca
    25441 gtctttgaaa atgtagctta cgccatggaa gttattggtg aaaagcgccg ccacattaaa
    25501 aaacgcgtgc cagaggtact cgatttagtt ggcttgaaac ataagatgcg ttcttttcca
    25561 agtcagctat caggagggga gcagcaacgt gtggccattg cgcgtgcgat tgttaacaac
    25621 cctaaattat tgattgcaga tgaaccgaca gggaatttag atcctgagat ttcatgggaa
    25681 attatgcagt tacttgaacg tattaatgtt cagggaacaa ctatcttaat ggcgacacac
    25741 aacagtcata ttgtgaatac attccgtcat cgtgttgttg ctattgaaga tggtcgcata
    25801 gtacgtgatg aagaaaaagg agattatggt tacgatgatt agatactttt tccgtcatat
    25861 ttgggaatcc attaaaaatc ttaaacgcaa cttttggatg acatttgctt cagttagtat
    25921 ggtggctgtt acattgactt tagttggtgt ttttgcggcg acattgttga atatacagcg
    25981 tgttgcttcg ggtgttgaaa ataatgtcca tatcaatacc tacttacaag ttgattcaac
    26041 tgatgctgca aaagttattc aaaatactgc cggtgaacct gttaataacg ataactacca
    26101 cagtgtttac gacaaaattg ctcagataaa aggtgtcaaa aagattacat tttctagcaa
    26161 ggatgaacaa ttgaaaaaat tgcaagaaac cttaggtgat gtttggaata tgtatgacca
    26221 agacactaat ccgctccaag atatctatct tattgagacc cagacgccta aacaagttaa
    26281 ggcgatcact aaaaagatca gaacgattga aggcgtagaa gccgcagatt atggagggat
    26341 taactccgat aaactattta agttttcaac attaattcaa acttgggggc tgatcggaac
    26401 agcaatgcta ttatttgtag ctgtctttct catttcaaac actattcgta tgactattat
    26461 gtctcgtaaa cgcgacattg aaattatgcg gttagttggt gctaaaaatt cttatattcg
    26521 agggcctttc ttttttgaag gggcttgggt tggcttgtta ggagctgttt taccatctct
    26581 tctgatttat tatggatatg atcttgttta taagcatttt gcacaagaat tacaacgtaa
    26641 taatctctcg atgtatccgc ttgatcctta tgtatattac ctgattggtg ctttgtttgt
    26701 cataggtatt atgattggtt cgcttggttc agtgctttct atgagacgtt atttaaaatt
    26761 ctaaaaaagc gctgctgacg aaacgtagcg accctcaaaa gttggacctc ttatgttatt
    26821 ccaaggactt cgttttgtat tgcacaggac tggtcctttt cattttgttt tgattcattt
    26881 gtttatttgt aataggcaat atagtttaaa atagcagttt ctaaggtttc aagagaagaa
    26941 aagcactcca aaagttagat gtttgatgta tctaactttt ggggtgtcat tcaaaattta
    27001 gtggctcttt tttagtaaaa tactatgatt tcagttttag gataacctca aacagtatct
    27061 aaaatagcta tgtcaatgaa aaaaggggtt agcatttttt tcgtgacaaa tggtagtaga
    27121 aggaccatgc ccaggataaa ctcggtaatg attaggtaag gtgaatagtt cttggcgaat
    27181 accagtaatg aggtcctcaa agttactggt aggtaagtca gtacgaccga tagtttcacg
    27241 aaatagagca tcgccagtaa cgactaattc atctgagtgg aaaacaaatg agactcctcc
    27301 caaagaatga ccaggtgttg gtaaaactgt gaattcaaaa ccatttagtt gatagggttg
    27361 ctttaattta aaaaagttct ctgccggtct tgctataaca gtaatgatat catcatgacg
    27421 gcctaagcca gataaattat catctgggga agatagccaa gcggcttctt tttctgaaac
    27481 ataaacaggt ggatgatcaa aagcatctct gaccaaatct aaactaaaaa tatgatcata
    27541 gtgagtatgc gttaagagga tagccactaa aggtttttca aaggatttaa ttttagcaat
    27601 gatttcttgg ccgttacttc ctggatcaat gaggataaca gcttgatcat taacgaggta
    27661 ataagtattt tcaccagcaa tgtggtttat tgttttatag attttcataa ggatagtgta
    27721 ccaaaaaatc aagactttgt taaaaaaaga gtagcggaaa ataaatggca attagtttca
    27781 gaaaatatga gatctcacag caatttcttg acaccgtttt cataaaggtg tatcataaaa
    27841 gtaatcaata agccaagcct aaagctgaac ttagtttaag aacactgact ttttgagagc
    27901 aacctaatcg gttgactaaa aaatatgagg tggaagatat gtcaaaagtt gctattgtta
    27961 ctggtgctgg tcaaggaatt ggatttgcta ttgcgaaacg tcttcatgca gacggcttta
    28021 aaataggcat tttagactat aatgaagaga ctgctcaggc tgcggttgat aaactatcac
    28081 ctgaggatac tgttgcagtt gtagcagatg tttcaaaacg tgaccaagtt tttgatgctt
    28141 tccaaaaagt tgtagatact tttggtgatt tgaatgttgt tgttaacaat gcaggtgttg
    28201 ccccaacaac ccctcttgac acgattactg aagagcagtt tgaaaaggct tttgcaatca
    28261 atgtcggagg aacgatttgg ggaagccaag cagctcaaaa acattttaga gaattaggtc
    28321 atggcggaaa aattataaat gcaacgtcac aagcaggatg tgaagggaat cctaatttga
    28381 ctgtttatgg tggtacaaaa tttgcagttc gtggtattac acagactttg gcaaaggatt
    28441 tggcatcaga aggaatcaca gtcaatgctt acgcaccagg tattgttaaa acacctatga
    28501 tgtttgatat tgcccatgaa gttggtaaaa atgcaggcaa agatgatgaa tggggtatgg
    28561 agcaatttgc aaaagatatc actttgaaac gcttgtctga accagaagat gttgctaatg
    28621 cagtaggctt cctagcggga gatgattcaa attatatcac tggacaaaca atagttgtcg
    28681 atggtggtat ggtattccat taaaaatgat taatactgac actgtgagtg aaactcacag
    28741 tgttttttat acttcttaaa aaattatcct atcttggtta ttggagtgat ggcacctttg
    28801 agatatagtc atgttttgtt ttatagatat agcgtgctat aatagactta ctatgaccca
    28861 gaaaaaactt agaaaatatg cagtagtgga cttggaagct actggagcag gtcccaatgc
    28921 ttctattatt caggttggga ttgttattat ccaaggaaat aaaattattg atagttatga
    28981 aacagatgtt aatcctcatg aatctttgga tgagcatatt gttcatttga caggtattac
    29041 ggataagcag ttggctaaag ctccggattt tggtcaagtg gcgcatcaca tttatcaatt
    29101 gattgaagat tgtatttttg ttgcccacaa tgtaaagttc gatgcaaatt tattggcaga
    29161 agctcttttt ttggaaggat atgagttaac aataccacgt gttgatactg ttgaattagc
    29221 ccaactattt ttccctcgct ttgaaaagta taaccttggt cacctatcta ggcagctcaa
    29281 tattgatttg gcagaagctc atactgctat tgcagatgca agagctacag ctatactgtt
    29341 tttaagactt ttacaaaaaa ttgagagcct tccaattgag tgcttagaaa gcttattagt
    29401 ctattcagat agcctgctat ttgaaacagc aatggtcatt caagaaggat tagccaaagc
    29461 caaaccttat gatcccaaca aatacattaa aatcagacag attctcttac caaagggctc
    29521 aaaagctctc aagccttatc aaatatcaaa aagcttccct attaatatgg cactattagg
    29581 tctggaagaa aggcctaaac agactcaatt tgctcagtta attgacgaag attaccatca
    29641 gggagtagct agttttattg aagctcagac aggtattgga aaaacctacg gctacctgct
    29701 accccttttg gcaaaagaag atcaaaacca aatcattgtt agtgtgccaa ccaaacttct
    29761 tcaagaccaa ttaatggctg gtgaagtagc tgctattcaa gaacaatttc acatcgcctg
    29821 ccatagttta aaagggcctg ccaattacct aaagctagat agctttgcag atagtttgga
    29881 ccaaaatgac cagaaccgtt tggtgaatcg ttataaaatg caattattgg tttggctctt
    29941 agaaactaag acaggagacc ttgacgaaat caaacaaaag cagcgctttg ccgcttattt
    30001 tgagcagctt aagcacgatg gagacattaa gcagtcttct gaattttacg attatgattt
    30061 ttggagagtt agttatgaaa aagccaaaac agcccgtctc ctgattacca accatgctta
    30121 ttttttacac cgtattcaag atgacaagga ctttactaga aacaaggtct tggtctttga
    30181 tgaggcccaa aagctgatgc tccaattaga tcaattatca cgtcatcagc ttaacctgac
    30241 ggttttttta caaacaatac aggccaagtt aagcaaccct ttacctcttt tagaaaaacg
    30301 cttattggaa agcttgtcgt ttgaactggg acaagtgtca agtgattact atcaaaataa
    30361 agagcaccag cttgctcatg attggtctcg tatagctggc tacgccaaag aattaacagg
    30421 agcagattat caagagttac aagccttttt tgctacctca gatggtgact actggcttag
    30481 tagcgaaaag caagaggaga agcgagtgac ttatctaaac agtgctagta aggcatttat
    30541 tcatttccaa cagctcttac cagaaacggt gaaaacttat tttgtttctg ccactttaac
    30601 catcagctca gaagtaacct tggcagacct attaggtttt gaagagtatc tctatcatgt
    30661 cattgaaaag gataaaaagc aagaccagtt ggtgcttgtt gatcaagagg cgcctatcgt
    30721 gacagaagtc agtgaccaaa tctatgtgga agcaattgca aaacgaatcg aaagcttgaa
    30781 gcaagagggt tatcctattt tagtgctttt taattctaaa aaacacttgc tgttggtttc
    30841 agactatcta gaccaatggc aggtgcctca cttagcgcag gaaaagaatg gaacagctta
    30901 taatattaaa aaacggtttg atcaaggaga gcaaactatt ttgcttggtt taggttcttt
    30961 ttgggaagga gttgatttta ttcaagcgga tcgtatgatt acccttatcg cacgattgcc
    31021 ctttgataac ccagaggatt tctttgttaa gaaaatgagt cattatctat tggaaaaagg
    31081 taaaaatcct ttcagagatt acttcttgcc aatgactatt ttgcgattaa aacaggctat
    31141 tggtcgcacg atgcgtcgaa aagatcaaaa gtcagtggtt attattttgg atcgtcgtct
    31201 ccttacaaag tcctatggac aagttatttt ggaaggtctc ggtcaggaat ttttgatttc
    31261 tcaacaaaat tttcacgatt gtctagtaga aacggactgt tttttgatat aatagaaagg
    31321 atctattata tcagaaaaat ttttaatggc gttaagcaca atcaactaac atttaaatta
    31381 gtttgaactt ttattatgct cttttagaca actgttcaaa tgttttcgaa ttgttttttt
    31441 gataaggaca ataaatgaac aaatttttgg ttttagtaaa cccaattact gttcttttca
    31501 ttagtgtcag ttgctatcaa aacagcttgt catagttcgt gcgatcagta gcgagtattg
    31561 gtaaaactga aaccgtagat tatgaaaaaa tgatctgttg atcattaatt aatctgaaga
    31621 taagaagtcg ataaaaagga gatacgatgc ccaaactatc aaagcgagtt ttagaaatga
    31681 aagagagtgt tactctggct gcaggtgcta gagctaaggc tttgaaagcg cagggccatg
    31741 atgtactgaa tttaacttta ggagaaccag atttttttac acctaagcac attcaagaca
    31801 aggcgattga atctattcaa aatggtacgg ctagctttta tacaaatgct tctgggcttc
    31861 cagaattaaa agctgcgatt gccacatatc tgaaaaatca gtatgggtat cacttgtctc
    31921 ctgatcagat tgtggcagga acaggtgcca agttcatcct ttatgccttt tttatggctg
    31981 ttttaaatcc tggtgaccaa gttctcattc caacaccata ttgggtatct tattctgacc
    32041 aagtaaaaat ggcagaaggt cagccgatct tcgttcaagg actagaagaa aatcaattca
    32101 aggtaactgt tgaccagctg gaaagagcaa ggacaagtaa gactaaagtt gtccttatca
    32161 attctccttc caatccaaca ggcatgattt atggtgctga ggaattaagg gccattggag
    32221 aatgggcggt gcacaacgat attcttattc tggcagatga tatttacggg tccttagtct
    32281 ataacggcaa tcagtttgtt cctatttcaa cactctcaga agcgattcgt cgtcaaacca
    32341 ttacggtcaa tggcgtggct aaaagttatg ccatgacagg ctggcgggtt ggttttgcag
    32401 caggtgaacc agagatcatt tcggcaatga gtaagatcat cgggcagact acctctaacc
    32461 tgacaaccgt ttcacaatat gctgctatcg aggctttctg tggtagtcag tcatcacttg
    32521 aagagatgcg attagcattt gaagagcgcc ttaatatcac ttatccattg ttgtgtcagg
    32581 tccctgggtt tgaggttgtt aaaccacaag gagcttttta cttctttcca aacgttaaga
    32641 aagccatgga aatgacaggt ttttccgatg tgacaagctt tgccaatgct attttagagg
    32701 aagtcggatt agctgttgtg agtggagcag gctttggcgc accggaaaat gttcgtctga
    32761 gttatgctac agatatcgaa acccttaaag aagctgttcg tagactgcat gtctttatgg
    32821 aaagtaatga aattaattaa ataaaaatag agagaaactt atgtcaaaaa aacttatttc
    32881 aattgttgat gttaaagatt atgttggtca agaagttact attggtgctt gggttactaa
    32941 caaatcaggt aaaggtaaga ttgcgtttgt acagttgcgc gatggttctg cttttttcca
    33001 aggtgtcgct tttaaaccaa acttcattga aaaatatggt gaagaatcag gtcttgaaaa
    33061 atttgacgtt attaaacgtc tcaatcaaga aacatctgtt tatgtaacag ggattgttaa
    33121 agaggatgag cgttctaaat ttggctatga gcttgatatt actgaccttg aaatcattgg
    33181 agagtcacat gaatatccta taactcctaa agagcatggg acagacttct tgatggacaa
    33241 ccgtcacctt tggttgcgtt ctcgtaaaca aatggctgtt atgcaaattc gtaacgctat
    33301 tatttatgca acttatgaat tctttgacca aaatggtttt atcaaatttg atagcccaat
    33361 tttatcagaa aatgcagcag aagattcaac agagttattc gaaacagact attttgggaa
    33421 accagcattt cttagccaat ctggtcaatt ataccttgaa gctggagcaa tggctctagg
    33481 ccgagttttc gactttggtc cagtctttcg tgctgaaaaa tctaaaacac gtcgccattt
    33541 aacagaattt tggatgatgg atgctgagta ttctttcttg tcacatgagg aatcacttga
    33601 ccttcaagaa gcttatgtta aagcattgat ccaaggcgtt ctagatcgtg cgcctcaagc
    33661 acttgatatt ttagaacgtg atgttgaggc tctcaaacgt tatatcacag agccattcaa
    33721 gcgtgtttct tatgatgatg ctattacact tcttcaagag catgaagcag atgaagatac
    33781 agattatgaa catttagagc atggtgatga ctttggttcc ccacatgaaa cttggatttc
    33841 taattacttt ggagtaccga catttgtagt gaattaccca gcaagcttta aagcatttta
    33901 tatgaaacca gttcctggaa atccagaacg cgttctttgt gctgatcttt tagctccaga
    33961 aggttatgga gagatcattg gcggctcaat gcgtgaagac aactacgatg ctcttgtggc
    34021 taaaatggat gaactaggta tggataaatc agaatatgac ttttaccttg accttcgtaa
    34081 atatggctct gttcctcatg gcggttttgg tataggtatt gaacgtatgg taacttttgt
    34141 tgctggtacc aaacatattc gcgaagctat tccattccca cgtatgttac atcggattag
    34201 accctaataa tacaaaaaag ttcatgtcat ctatgaactt tttgtattgg taagaagtga
    34261 gtgtgttata aaaacatcaa tatgtcctaa aggagagata agaaatagta gagtttgaac
    34321 ctacatcctt tgtgaagata aattttggaa gtttagtaga tcagttagca gataagacaa
    34381 tatagctttg ctcaagggat attttataga caagtatttg gactacgatt atcaaataga
    34441 cactctcatt tgatactaaa aaggtctcgt ctattcatat aataggagag ctacgggagt
    34501 tattattaaa attagctgat ttttacagtt caaaatgtgt taccactttt tcacttctta
    34561 gctttcttat gtatgtggta taatgaaggt ggacggttcg atagagaaag ggaaattgta
    34621 aatgtcagac aaacacatta atttagttat tgtgacagga atgagcggcg ctggaaaaac
    34681 agttgccatt cagtcttttg aggatctagg ctactttacc attgataata tgcccccagc
    34741 cttggttcca aaatttttag aattaattga acaaaccaat gaaaatcgta gggtggcttt
    34801 ggttgtcgat atgagaagtc gtttgttttt caaggaaatt aattctacct tagatagtat
    34861 tgaaagcaat cctagcattg attttcggat tctttttttg gatgcaacgg atggagaatt
    34921 ggtgtcacgc tataaagaaa ccagacggag ccaccctttg gctgcggacg gtcgtgtgct
    34981 tgatggtatt cgattggaaa gagaactcct atctcctttg aaaagcatga gccaacatgt
    35041 ggtggataca acaaaattga cccctagaca attgcgtaaa accatttcag accagttttc
    35101 tgaagggtct aatcaaccct ctttccgtat tgaagtgatg agctttgggt tcaaatatgg
    35161 tcttcctttg gatgcggatt tggtttttga tgtgcgtttt ctacccaatc cttattatca
    35221 ggtagagctt cgtgaaaaaa caggactaga tgaggacgtt tttaattatg tgatgtctca
    35281 cccagaatca gaggtgtttt acaagcattt gttaaacctt attgtcccta tcttaccggc
    35341 ttaccaaaaa gaagggaagt ctgtcttgac ggtggctatt ggctgcacag gaggccaaca
    35401 ccgcagcgtt gcctttgccc attgcttggc agaaagtctg gcaacagatt ggtcggttaa
    35461 tgaaagccat cgtgatcaaa atcgtcgtaa ggaaacggtg aatcgttcat gaaaaatcct
    35521 aaaatgactg ttataggtgg gggtactggc atctccatta tcctaaaaag ccttcgtaat
    35581 gaagcagttg atattactgc tgtggtcact gttgcagatg atggtggttc ctcaggagaa
    35641 cttcgtaatg ccatgcaatt agctccgcca ggagacttac ggaatgtctt gttagcgatg
    35701 agtgacatgc caaaatttta tgagcgggtt ttccaatacc gttttaacga gagtgatgga
    35761 gccttggctg gtcaccctct aggcaatctc attattgctg gtatctctga aatgcaaggc
    35821 tcaacctaca atgccattca aattttaacc aaatttttcc atattacagg taaaatttac
    35881 ccctctagcg agcaggcctt gacccttcat gctgttttta aagatgggca tgaagtagca
    35941 ggagaaagtt ctattgccaa atacccaggc atgattgacc atgtctatgt gaccaacacc
    36001 tacaacgacc aaaagcctca ggccagtcgt aaggtggttg aagctattct agaaagtgac
    36061 atgattgtct tgggaccagg ctcactgttt acctctattt tacctaattt ggtcattcca
    36121 gaaattaaag aagctttgcg ccagactaaa gcagaagtgg tgtatatttg taatatcatg
    36181 acccagtatg gtgaaacaga acaattttca gatgcagacc atgtggctgt tttaaatcag
    36241 cacttaggaa gagatttgat tgatacggtt ttggtaaatg tggctaaggt gccgcaggct
    36301 tacatgaatt ctaacaaatt tgatgaatac ctcgttcagg ttgatcacga ctttgctggc
    36361 ctttgcaggg ctgctaagcg tgtgatttcg tcttattttt tacggttgga gaatggcgga
    36421 gcttttcacg atggtaactt agtggtggaa gaattaatga atttagtgag gatagtcaag
    36481 caatgagttt tacaaccaag gtcaaagagg aattaattca cttgtccaca ggtgacaaca
    36541 atgaattggc cgccattatc aaattatcag gcagcttggg cttagctcac caaagccttc
    36601 atttatccat taccactgaa aatgctaaaa ttgcccgcta catttattct cttattgaag
    36661 acgcctatgt tatcgtgcca gaaatcaggt atcatcaaaa gacgaacctg cgcaaaaacc
    36721 gtgtttacac cgtctatgtt gagcaaggtg tggaaaccat tttagccgat ttgaaattag
    36781 cggactcctt ttttggtctg gaaacaggca tcgaacctca ggttttatca gacgataatg
    36841 ctggccgttc ttatcttaaa ggggcttttc tagcggcagg tagcatcaga gatcctgagt
    36901 caggcaagta tcagttagaa atctattcag tttatcttga tcatgctcaa gatttagctc
    36961 aactcatgca aaaatttatg ctagatgcca aaaccatcga gcataaaagc ggtgcagtta
    37021 cttatgtgca aaaggcagaa gatatcatgg actttttaat tataattggt gccatgtcct
    37081 gcaaagaaga ctttgaagcc atcaaattac ttcgagaagc tcgaaatgat attaaccgtg
    37141 ccaataatgc agaaacagct aatattgcca aaactatcag tgctagcatg aaaaccatta
    37201 ataatattat taaaatcatg gacacaattg gtttagaaag tttaccgatt gaattgcaac
    37261 aggtagccca gcttcgggtt aagcatccag actattccat tcaacaagtt gctgatgctc
    37321 ttgagttccc aatcaccaag agcggggtca accatcgctt gcgtaaaatc aataaaattg
    37381 cagatgactt atagaacatt tttatcgtat gagcctttgt tcatacgatt tttttgtcta
    37441 aaagtcgttt tccattgttt ttttgaagtg tctgatgttc tgtgatatga taaaagggat
    37501 aataacgttt gtaaaggaga ctgataatgg catgtacaac tatactcgtt gtagtgccta
    37561 aataatgctt ttaaaactta aaaataatat cgatgttatc catagtaacc tcgactctat
    37621 ctatcaattg cttaactatc ctagattgaa catcatacga agattttcta atgtcaatgt
    37681 tatccatcag cattccaaga gagtcttcgt ttttcttgtc taaataattc aatttaattg
    37741 ctttgttata atcatctttt aaatgattga gttcttcgat gtcttttttt agttttggta
    37801 ggtcaatcaa atcattaata tataaatcgt ttagacgatt gattttttta tcgattatct
    37861 ctatttcttt ttttaaa
//
LOCUS       DAUGUF010000018        37640 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUGUF010000018 DAUGUF010000000
VERSION     DAUGUF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37640
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.018"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            118..813
                     /locus_tag="VIB71_000899"
     CDS             118..813
                     /locus_tag="VIB71_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEQ8822646.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            921..1442
                     /locus_tag="VIB71_000900"
     CDS             921..1442
                     /locus_tag="VIB71_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEQ8822647.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            1603..2145
                     /locus_tag="VIB71_000901"
     CDS             1603..2145
                     /locus_tag="VIB71_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822648.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            2269..3048
                     /locus_tag="VIB71_000902"
     CDS             2269..3048
                     /locus_tag="VIB71_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEQ8822649.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFVTNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            3836..4432
                     /gene="recR"
                     /locus_tag="VIB71_000903"
     CDS             3836..4432
                     /gene="recR"
                     /locus_tag="VIB71_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEQ8822650.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            4533..5579
                     /locus_tag="VIB71_000904"
     CDS             4533..5579
                     /locus_tag="VIB71_000904"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEQ8822651.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            5778..7169
                     /locus_tag="VIB71_000905"
     CDS             5778..7169
                     /locus_tag="VIB71_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEQ8822652.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGTPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVE
                     RLVTDKNCDSYQP"
     gene            7250..7945
                     /locus_tag="VIB71_000906"
     CDS             7250..7945
                     /locus_tag="VIB71_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEQ8822653.1"
                     /translation="MDFFAIDPIGLPHISLIFYLLSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLCMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLAFAFSKEK"
     gene            8193..9737
                     /locus_tag="VIB71_000907"
     CDS             8193..9737
                     /locus_tag="VIB71_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEQ8822654.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            10044..11663
                     /locus_tag="VIB71_000908"
     CDS             10044..11663
                     /locus_tag="VIB71_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8822655.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            11790..13790
                     /locus_tag="VIB71_000909"
     CDS             11790..13790
                     /locus_tag="VIB71_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEQ8822656.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IVPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNMLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(13814..14092)
                     /locus_tag="VIB71_000910"
     CDS             complement(13814..14092)
                     /locus_tag="VIB71_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEQ8822657.1"
                     /translation="MTTKKAYMYVLECVDKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(14082..14936)
                     /locus_tag="VIB71_000911"
     CDS             complement(14082..14936)
                     /locus_tag="VIB71_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEQ8822658.1"
                     /translation="MKADFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIIEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
                     KGKPNHDH"
     gene            14976..15716
                     /locus_tag="VIB71_000912"
     CDS             14976..15716
                     /locus_tag="VIB71_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEQ8822659.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKLAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            15916..16578
                     /locus_tag="VIB71_000913"
     CDS             15916..16578
                     /locus_tag="VIB71_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEQ8822660.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            16559..18802
                     /locus_tag="VIB71_000914"
     CDS             16559..18802
                     /locus_tag="VIB71_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEQ8822661.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLIQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
                     FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGWTS
                     WHLETVR"
     gene            18873..19913
                     /locus_tag="VIB71_000915"
     CDS             18873..19913
                     /locus_tag="VIB71_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEQ8822662.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKVDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILDRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            20010..20615
                     /locus_tag="VIB71_000916"
     CDS             20010..20615
                     /locus_tag="VIB71_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEQ8822663.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
     gene            20782..21008
                     /locus_tag="VIB71_000917"
                     /pseudo
     CDS             20782..21008
                     /locus_tag="VIB71_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            20993..21241
                     /locus_tag="VIB71_000918"
     CDS             20993..21241
                     /locus_tag="VIB71_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822664.1"
                     /translation="MDADLAQMDALGLYYDDNHLSLVNTVKVYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            21238..21828
                     /locus_tag="VIB71_000919"
     CDS             21238..21828
                     /locus_tag="VIB71_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEQ8822665.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSIPDMQEYSLVYSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTAYYLQGLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLITLYSSGL
                     GGATQASEEVNGLGYVQLVQLTYVINEWHRVNHNMI"
     gene            complement(21942..23162)
                     /locus_tag="VIB71_000920"
     CDS             complement(21942..23162)
                     /locus_tag="VIB71_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ8822666.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQNLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(23169..24197)
                     /gene="queA"
                     /locus_tag="VIB71_000921"
     CDS             complement(23169..24197)
                     /gene="queA"
                     /locus_tag="VIB71_000921"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEQ8822667.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            24399..25103
                     /gene="nagB"
                     /locus_tag="VIB71_000922"
     CDS             24399..25103
                     /gene="nagB"
                     /locus_tag="VIB71_000922"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEQ8822668.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDI
                     EAEAKRYDQIIAGHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIKANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            25222..25938
                     /locus_tag="VIB71_000923"
     CDS             25222..25938
                     /locus_tag="VIB71_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8822669.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPIHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            26233..27195
                     /locus_tag="VIB71_000924"
     CDS             26233..27195
                     /locus_tag="VIB71_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEQ8822670.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFCCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIEGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            27208..29013
                     /gene="pepF"
                     /locus_tag="VIB71_000925"
     CDS             27208..29013
                     /gene="pepF"
                     /locus_tag="VIB71_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8822671.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFS
                     GHLLDSSANLLTITDTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMTKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            29389..30585
                     /locus_tag="VIB71_000926"
     CDS             29389..30585
                     /locus_tag="VIB71_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEQ8822672.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     VLRLKK"
     gene            30651..31358
                     /locus_tag="VIB71_000927"
     CDS             30651..31358
                     /locus_tag="VIB71_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEQ8822673.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPKLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            31421..32476
                     /gene="prsA"
                     /locus_tag="VIB71_000928"
     CDS             31421..32476
                     /gene="prsA"
                     /locus_tag="VIB71_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ8822674.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            32863..35481
                     /gene="alaS"
                     /locus_tag="VIB71_000929"
     CDS             32863..35481
                     /gene="alaS"
                     /locus_tag="VIB71_000929"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEQ8822675.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYNPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKHDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            35841..36056
                     /locus_tag="VIB71_000930"
     CDS             35841..36056
                     /locus_tag="VIB71_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8822676.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            36053..36814
                     /locus_tag="VIB71_000931"
     CDS             36053..36814
                     /locus_tag="VIB71_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEQ8822677.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            36833..37528
                     /locus_tag="VIB71_000932"
     CDS             36833..37528
                     /locus_tag="VIB71_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8822678.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIAGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
BASE COUNT        11537 a         6557 c         7799 g        11747 t
ORIGIN      
        1 atagtcacat tatgattttc aataaagtca gaatagacta gcttttttgc tatatttttt
       61 gtaaaatagg aattgtaaaa aggtagcaac ctttaaatta aaaggagata ttaactcatg
      121 gtaaaattgg ttttcgctcg ccacggtgag tcagaatgga acaaagctaa cctcttcact
      181 ggttgggcag atgttgatct ttcagaaaaa gggacacaac aagcgattga tgcaggtaaa
      241 ttgatcaaag aagcaggtat tgaatttgac cttgctttca cttcagtatt gacacgtgct
      301 atcaaaacaa ctaaccttgc ccttgaaaat gcaggtcaat tgtgggttcc aactgaaaaa
      361 tcatggcgct tgaacgagcg tcactatggt gctttgactg gcaaaaacaa agctgaagct
      421 gcagaacaat ttggtgatga acaagttcat atctggcgtc gttcatacga cgtgttgccg
      481 ccagctatgg ctaaagatga tgagtattca gcacacaaag accgtcgtta tgctgatctt
      541 gacccagccc ttattccaga tgctgaaaac ttaaaagtaa ctcttgaacg cgcaatgcct
      601 tactgggaag aaaaaattgc tccagctctt cttgacggta aaaacgtctt tgttggtgca
      661 catggtaact caatccgcgc tcttgtgaaa cacattaaag gtctttcaga tgacgaaatc
      721 atggatgtgg aaattccaaa cttcccacca cttgtttttg aattagatga aaaacttaac
      781 attgttaaag aatactacct tggtggtgaa taacttaaaa accagacttt ggtctggttt
      841 tttgggttct atatcctaag aagaaagaaa accctgctta aaaatatgat atgatagaaa
      901 taaaaaagga tagatagatt atgaaagcag aagatcgtcg tcaaaaaatt attgagtgct
      961 taaatagtga acaaaaagct gtatctgcta ctcgtttagg taagttatta ggagtgagtc
     1021 gccaagtaat tgttggagat atagctcttc ttcgagctca gcagattgat attatttcga
     1081 ctccaaaagg ttatattatg tcaacagcgc tttatagtca ccaattttgt gcacgtattg
     1141 tgtgccaaca taatgtagaa gaaactaaaa aagaattaga aattatttta gctcatcaag
     1201 ggattattac gacggtagag gtagaacatc ctatttacgg tatgataaca gcccctttaa
     1261 atattaagac acactctgat gtaactaatt tcatgtccaa actcagtcaa tctaaagcag
     1321 agttattgtc ttcgttgaca gaaggactac atagtcactt aatttcgtgt cctagtcaag
     1381 aagccttttt agctatcaag catgatttag aattagcagg tatcttatac aaaggaatat
     1441 aactacagta tattatgcca ttgatggttg ttatgaatac catgctaaaa tattctattg
     1501 attatttatc agcaacaagg tatcgtttaa aaataccaaa agatacaggt gtcttgatag
     1561 ttattggttt ttaaggtata ctatttttga aaaggagata aaatgactaa aaaaccaaca
     1621 caactaatag cttatacctc tattttggtc gcatttgcga ttttgattcc gataatcatg
     1681 cctcttaagc ttattattgg accagcttcc tttactctgg cgagccatgt tcctttgttt
     1741 ttggctattt ttatgtcgat tccagtagca attttggtcg ctcttggtac cacattaggt
     1801 tttttattag ctggacttcc tttaattatt gttttaagag cactctctca tttattgttt
     1861 gctattttgg cagcgtggtg gttaagtaga aaaccacaac tgatgacatc ggcagtaaaa
     1921 tgttttagtt ttgcgttttt cattaatgtc attcatggct tggctgaatt tttagttgtc
     1981 tatattttaa cagcaaccac agcaacttct atgtcttatt tttggtctat gctaggcttg
     2041 attggcttag gttcgcttat tcatggcata ttggatttct atcttgcttt agttctatgg
     2101 cgttttttag caaaaaactt aaaacttccc accataaatg cctaagacta aaatagagat
     2161 agttatatga taatgacgag ccctttcttg ttgaaagggc ttgcattttt taggaaaatt
     2221 gatatactaa agtgtgtgtt tgtgaataca gtaacaaaag gagatatcat gaaaacacca
     2281 gaacagattt tagaagcaac tattcatatt ggggaacata aggttaccaa aacttttttg
     2341 gctaaatcta tcttaggctt tattggtgga gcgatgatta gccttggtta tttactatac
     2401 gtgagaattg ccgccagtgg tttagaaact tttggtgctt tttccagtat cgtaggagct
     2461 tgtgcttttc cgattggtct aattattatt ttaatggcgg gtggagaatt aattacaggg
     2521 aacatgatgg ctgtttctgc agctttgttg gccaaaaaaa ttaagtttag cgagcttgcc
     2581 aagaattggc ttatcattac cttgtttaat gtgattggag ctgtttttgt agcttttgtg
     2641 tttggtcatt ttctaggctt gacatcagct ggtattttta aagaagaagt gattgaggtg
     2701 gcccatgcta aaatagcagc gagccctttg caggcactag tatcaggaat tggttgtaac
     2761 tggtttgttg gtttggcctt gtggctatgc tatggggcaa atgatgctgc tggtaaattc
     2821 cttggtactt ggtttcctgt catgaccttt gtagcccttg gttttcagca tagtgtagca
     2881 aatgcttttg tcattcctgc tgctattttt gaaggaggag caacatggtt ggattttgtc
     2941 actaatttta tttttgtcta tagtggtaat attatcggtg gagccatttt tgttagtttt
     3001 ttatatttta aagtttacta tcatccgcaa aagagtaaaa ctcaatgaga aaatattttt
     3061 ttagactgag ggcgtcctat tctcagtctt ctttttataa tttatggtaa aataagaagc
     3121 gaagtttaaa aaatttagct aaatatggtt agtttattcc ctaaaaaagg agtattccca
     3181 aaaaatccgt aaaaagaatt tgctatggga gtagttccca aaataatgca gatcattagt
     3241 tgtctttcaa aaatagcctt gatagggtaa aaagtggaca gtgatgcagc aacagattca
     3301 tcaggcgtac aaactgtctt atggtttgtg cttagagatt tcttaataat gcttttggta
     3361 atacactttt agtgaagaaa gtgtagcatg aaagcttaaa gataaccatg agtttgcttt
     3421 atgcactatt gttgagaaaa atagcatagt caattgagta aacatcattt ctgcatggaa
     3481 tgaaacaatt cctataaact tatatcataa ggatggtttg cggtttctaa aaaagtaaca
     3541 tgaatcaaaa aacaaaagcc aaatatccca aggccaaggt aacaagtcga gtaaaaaagt
     3601 ttttacttgg ctaatccaaa cggttctgtc acgattcacg ctaaaattgg aactgctgag
     3661 acttgtatca cagacaattc agatcagacc ttagtaactt acaacttaaa tgtagtagct
     3721 tataatacaa ataacgaaga taatattgcg gttgctgtac atattacgaa tatatcggca
     3781 aagatatgag ggcgctttat gtggcgatat atggaaaaca ataaaggaga acttagtgct
     3841 ttatccaaca cccattgcaa agttaattga cagttactct aaacttccag gaattggtat
     3901 caagacggcg acgagattag ccttttatac tattggaatg tcaaatgaag atgtcaatga
     3961 ttttgctaaa aacttattag cagctaaaag agaactgacc tattgttcga tttgtggaaa
     4021 ccttaccgat gacgatcctt gtcacatttg cacagacacg agccgtgatc agacgaccat
     4081 tctggtagta gaagatgcta aagatgtttc tgccatggaa aaaatccaag agtatcatgg
     4141 ctattatcat gtgcttcacg gcttgatttc gcctatgaat ggtgtggggc cagatgacat
     4201 caaccttaaa agtttaatta cccgtttaat ggatggtaag gtgagcgaag ttatcgtagc
     4261 taccaatgcc acagcagatg gggaagcaac gtccatgtat atttcacgtg tcttgaaacc
     4321 agccgggatt aaggtaactc gtttggcaag aggtctcgca gtaggttcag atattgagta
     4381 tgctgatgaa gtaacattat tgagagctat tgagaatcgt actgaacttt aatgatcatg
     4441 ttggtgcctt tactcgcaaa gagaggtttt gaaaaggcta catctttttg ttataataaa
     4501 aaaacattca attcagataa gaaaggttag ctatgtccaa acaaacgtta gttctattat
     4561 acggaggccg ctcagcagaa cgtgaagtct cagtgctttc agcagagagt gtgatgcgag
     4621 cagtcaacta tgataagttc ttagtaaaaa cttattttat tactcagatg ggccaattta
     4681 tcaaaactca gcaattttca gaaaagccat cggaatcaga acgcttgatg acaaatgaga
     4741 cgatagagct aactcaaaaa ataaaaccaa gtgatatcta tgaagaaggt gcagttgtat
     4801 ttcctgtatt acatggacct atgggagaag atggctctat ccaaggtttc ttagaagtgc
     4861 ttagaatgcc atatataggg actaatgtca tgtcttctag catagctatg gataaaatta
     4921 ctactaaacg tgtcttagaa tcaattggaa ttccacaagt tgcctatact gtttatattg
     4981 acggacaaga tttggaggct tgtttagttg aaactttagc aagacttact tttcctatct
     5041 tcgtaaaacc agctaatatg ggttcttctg tggggatttc caaagcccaa acaaaagtag
     5101 aattaagaaa agcgattcag ttagctctga cctatgacag tcgtgtcttg attgaacaag
     5161 gcgtggttgc cagagaaatt gaagttggtc tccttggaaa tgataaggtt aaatcaactc
     5221 taccaggaga agtaatcaag gacgttgatt tttacgacta ccaagcaaaa tatgttgaca
     5281 ataagattac gatggccatt ccagcagatg tagaccagag tattgtgaca gaaatgcgtt
     5341 cttatgctga agtagccttt aaagccttag gtggttgtgg gttgtctcgt tgtgactttt
     5401 tcttgaccca agacggacag gtttacctta acgaattaaa caccatgcca ggatttaccc
     5461 aatggtctat gtatccactc ttatgggaaa atatgggatt ggcttatcca gatttgattg
     5521 aagagctggt gacactggca caagaaatgt ttgaccagcg tgagagccac ctgatttaaa
     5581 cctatgagat gaataaatat tgacttggat ggaacggcaa acatcgtcaa gatgtgacgt
     5641 tcgtcctttt tttgttgctc ttttaggaag aatagtagag ccattaaggg agtttgacat
     5701 tttagaaatt tttctaatgt tttgtgctat aatagatagg acatcgtaaa tactagtgtt
     5761 cttagaaaga aaacaaaatg aaattaacct tacacgaagt ggctaaaata gttgacgccc
     5821 aaaataatgt gtctgactta gacgacgttc ctctgcatca cattgaattt gatagccgaa
     5881 agattacaaa aggagacctc tttttaccct taaaaggtca aagggatggt catgagttta
     5941 ttgatttagc ctttcaaaat ggagctgtcg ctactttttc agaaaaagaa ttgccgggga
     6001 cacctcacct tcttgttgaa gactgcctaa aagcttttca aaagctagcc cattattata
     6061 ttgataagat gcgcgtggat gttattgctg tgacaggctc aaatggtaaa acttccacca
     6121 aagatatgat aggagctgtc ctatcaacca cttacaaaac ttacaaaacg caaggaaatt
     6181 acaataatga gattggtttg ccttacaccg ttctccacat gcctgacgat acggaaaaaa
     6241 ttgttcttga aatgggacaa gatcacatgg gagatattcg tcttctgtct gaaattgcaa
     6301 ggcctcgtat tgcagtttta accttagtcg gcgaagctca tttagaatat tttggaagcc
     6361 gagacaaaat agcccaaggc aaaatgcaga ttgttgacgg catgaattca gatgggattt
     6421 taattgctcc gggagatccg attattgacc catatcttcc agaaaatcag atggttatcc
     6481 gttttggaaa tcagcaggaa attgacgtta ctggtattca agaagacaaa gatagcttaa
     6541 cgtttacaac aaatgtgtta gcaacacctg tgtccctacc tctaccagga aaatacaacg
     6601 cgaccaatgc tatggtagca gcctatgtag gaaaactatt ggcagtaaca gacgaggata
     6661 ttatagctgc tttacagact gtgacgttga caggtaatcg tacggagtgg aaaaaagcag
     6721 ccaatggtgc tgatatttta tcagatgtct acaatgccaa cccaacagcc atgcgtctga
     6781 ttttagaaac atttgctaac atagcaaaga accccggagg aaaaaagatt gcagtgctag
     6841 cagatatgaa agaacttgga aaggattcag tgatacttca ttctcagtta attgacagct
     6901 taacatcagg taatattgat cagcttgttt tttatgggga tcatattaaa gaattagcac
     6961 ggttggcaag tcaggtttat cctgctgagc aagtacatta ttttttaaaa actgaacaag
     7021 aagaccagtt tgaagccatg gcacaatatg ttcaaaacat tcttaatccc tttgatcaaa
     7081 ttcttttaaa aggcagccac tcgatgtcgc tagaaaagtt agtggaacga ttagtgactg
     7141 acaagaattg tgacagctat cagccttgat ttttataaaa ctttcagaga aaggcttgtt
     7201 ctctcatgaa gattaaggta taatgaaaaa aatatagaaa gggacgatta tggatttttt
     7261 tgcaattgac cccatcggac tgcctcatat ctcacttatc ttttacttgt tgtcactctt
     7321 gatagcgctt ttgcttgttt ttttgacttt tcaagcatat aggttaaaat cttatcgtta
     7381 ttttttcttg tttttacagt tatctcaggt gattggcttg tacacatggt acgtgttaag
     7441 ggggtttcct ttagatgaag ctttgccgtt gtatcattgt cgcatcgcta tgttagctat
     7501 cttttttcta cctgatcgta acaagtttaa gcaattatgt atggttttgg ggataggtgg
     7561 aacattcctt gcacttttat cgccagatct ttatccgttt agattatggc atgtagcaaa
     7621 tgtctcgttt tatcttggtc attatgcttt gttagtgaat ggtttgattt acctcttgcg
     7681 tttttacgat gccagtcagt taagactgct atcagtagta cgctatttag caactgttaa
     7741 ctttcttctt ctgttggtca gtttagccac gaaaggaaat tatggttttg tgatggatat
     7801 tccagtgatt catacgcgtc atttgctact taattttgtg atcgttacaa gtggcttgac
     7861 ttttatggtt aaaataaccg aatattttta ccttaaattt ggtgaagctc aacagctggc
     7921 atttgctttc tctaaagaaa agtaggtcgt tgaaaaagca cttaaaatca gctataataa
     7981 gaagagtctg ggatgatttc caggctcgat ttttttaaaa aagacactca ttgatagccc
     8041 aagataagtt ataataccag ttttgaagaa ctttagaggc taatcgtata tggagaaacc
     8101 caatgtagcc caactctttt gataaacaaa taatacctaa cgaaaataac tcagagaaaa
     8161 gctctgccat tttactatac aaggaaaaaa gaatgtcact tacagaagaa attaaaaaac
     8221 gccgtacttt tgccatcatc tctcacccgg atgctggtaa gacgactatt actgagcaac
     8281 tattatattt tggtggtgaa attagagaag cagggacagt aaaagggaaa aaatcaggta
     8341 cgtttgcaaa gtccgactgg atggatattg aaaagcaacg tggtatctct gttacttcat
     8401 ctgttatgca attcgattac gcgggtaagc gtgttaatat tttggataca cctggacatg
     8461 aggatttctc ggaagataca taccgtacct taatggctgt ggatgcggct gtcatggttg
     8521 tagattcggc taaaggtatt gaggcgcaaa cgaaaaaact ttttgaagtt gttaagcatc
     8581 gtaatattcc ggtttttacg tttattaata aattggaccg tgatggacgt gagcctttag
     8641 aactcttgga agaattagaa gaagttttag ggattgcttc ttatccgatg aactggccga
     8701 ttggtatggg acgcgccttt gagggcttat atgatttaca taataaacgt ttagaactct
     8761 ataagggaga cgagcgtttt gcaagtattg aagacggtga tcagctgttt gccaataatc
     8821 ccttttatga acaagtcaaa gaagatattg aacttcttca agaagcaggt aatgactttt
     8881 cagaacaagc tattcttgat ggtgacctaa ctccagtctt ttttggctct gcccttacga
     8941 actttggagt tcagactttt cttgatactt tcttggagtt tgccccagaa cctcatggtc
     9001 acaagactac agaaggtaat gttgttgacc ccttagctaa agatttttca ggttttgtct
     9061 ttaaaattca agctaacatg gaccctaaac accgtgaccg tattgctttt gtgcgtattg
     9121 tttctggtga atttgagcgc ggtatgggag ttaatttgac acgcactggc aaaggcgcta
     9181 agctctccaa tgttactcaa tttatggcag aatcacggga aaatgtgacg aatgctgttg
     9241 ctggggatat tatcggggtt tatgatacag gaacttatca agttggggat accttaacag
     9301 ttgggaaaaa taaatttgaa tttgaaccct taccaacttt taccccagaa atcttcatga
     9361 aggtttctcc gaaaaatgtt atgaagcaga aatccttcca caaaggtatt gaacaattag
     9421 tacaagaagg agcaattcag ctttataaga attatcagac aggcgaatac atgctgggtg
     9481 ctgtgggtca actgcagttt gaagtcttta aacatcgtat ggaaggtgaa tacaacgctg
     9541 aagttgtgat gacaccaatg ggtaaaaaga ctgttcgctg gatttcagaa gatgatttgg
     9601 atcaacgcat gtcctcaagc cgaaacattt tagctaagga tcgttttgac caaccagttt
     9661 tcctatttga aaatgatttt gcccttcgct ggtttgcaga caaataccca gatgtcactt
     9721 tagaagagaa aatgtaaccg aaacatgatt ttcaacagtc taacgttttg gagatcaatt
     9781 tactgagtaa ctttttaaaa gaaatgagtg gctagttatc tcttttgcag atttaagatt
     9841 ctatcaaaaa acgatatctt cacaactgta agcatattta tgatttagcg gataatcgtg
     9901 aaagcgtgtt attgcttata ttagccttat ttcctatctt tttgattcta attgtgttac
     9961 actagttagg ttgttaatca aacgacgaaa attaaaaggt ttataaggca gcttcgcact
    10021 gcctttttag aaaagagaaa caattgaaat ttacagaatt taacttatca caagacatcc
    10081 aatcagctgt tgttaccgct ggttttgaga aagcatctcc tatccaggaa atgacgattc
    10141 ctctcgcact agaagggaag gatgttattg gtcaagcaca aacaggaact ggtaaaacag
    10201 cagcgtttgg tctaccaacc ttgaataaga ttcgtactaa cgaaaatatc atccaagcat
    10261 tggtcattgc accaacgcgt gaattggctg tacaaagtca ggaagaattg ttccgttttg
    10321 gacgtgaaaa aggggttaag gttcgctctg tttacggtgg atcaagtatt gaaaaacaaa
    10381 tcaaagccct taaatcaggt gcccacattg tcgtgggaac accgggtcgc ttgttagatt
    10441 tgattaagcg caaggctctt attttagatc atgtggaaac cttaatcctt gatgaagcag
    10501 atgaaatgct taacatggga ttcttggaag acattgaagc tattattagt cgtgtcccag
    10561 cagaccgtca aaccttgctc ttctccgcaa cgatgccggc acctattaaa caaatcgggg
    10621 ttaaattcat gaaagaccct gaacatgttc aaattaagaa caaagaatta acaaacgtca
    10681 atgttgatca atactatgtt cgtgtgaaag aacaagaaaa atttgatact atgacccgtc
    10741 tgatggatgt taaccagcca gaattatcca tcgtttttgg gcggactaag cgccgagttg
    10801 atgaaattac acgtggcttg aaacttcgtg gtttccgtgc cgaaggaatc catggtgatc
    10861 ttgaccaaaa taaacgctta cgtgttatcc gtgatttcaa aaacgaccaa attgatattc
    10921 ttgttgccac tgatgtagca gcgcgtggcc ttgatatttc aggagttacc cacgtttata
    10981 actacgatat tacccaagat ccagaaagtt atgttcaccg tattggtcgt acaggtcgtg
    11041 ccggtaaatc tggtgagtct atcacttttg tctcaccaaa tgagatgggc tacctctcaa
    11101 tgattgagaa cttaacgaaa aaacagatga aacctcttcg tccagcaact gctgaagagg
    11161 cctttcaagc caagaaaaaa gtagccctca agaaaattga acgcgacttt gcggatgaga
    11221 ctattcgttc aaactttgat aaattcaaag gcgatgctgt ccaattggct gccgaattca
    11281 ctcctgaaga attagcttta tatattttga gcttaacggt tcaagatcca gatagcttac
    11341 cggaagttga aattgcacgt gaaaaaccat taccattcaa atatgtgggt ggtggtcacg
    11401 gcaataaaaa tggcaaaggt ggtcgtggac gtgacaaccg taaccgtggt gatcgccgtg
    11461 gcggctatcg tggtgaccgt aacagagatg agcgtgatgg tgaccgtcgt cgtcaaaaac
    11521 gtgataagcg tgatggtcac gatggcagtg gcaaccgcga tttcaaacgt aaatcaaaac
    11581 gtaatagtaa agactttttc aataaagaga aaaaatcaag tgctaaaaat actggttttg
    11641 tgattcgtca caaaggtgaa taagcttaaa gagagttgat gagagtcagc tctttttaat
    11701 tttctgaaaa agttgctttt ataatgggat ctgttataat ggtttcagtt atttcgttat
    11761 aatttttaaa aaattaggag gagtataaga tgtctgatag ccatcttact gcctttgaca
    11821 aagcttcaaa agcaggtttt attattgctt taggtattgt ttatggagat attggaacaa
    11881 gcccccttta tacgatgcag tctctagttg aaaatcaagg aggggttaat caggtttctg
    11941 aatcctttat tttaggatca atctctttaa ttatttggac actgaccttg atcacaacaa
    12001 tcaagtacgt tttgattgct ctaaaagctg ataaccacca tgaaggtggg attttttctt
    12061 tattcacctt ggtacgtaaa atgtcaccgt ggctcattgt tccggcgatg attggaggtg
    12121 caacactttt gtctgatggg gctcttacac ctgcggtaac agttacttca gctattgagg
    12181 gcttgaaagc cgttcctggt ctgagtcaca tctaccaaaa tcaaaccaat gtcattatca
    12241 caactctagt gattttaata gtcttgtttg gtattcagcg gtttggaaca ggttttattg
    12301 gtaaaatttt tggaccagtt atgtttatct ggtttagttt tctaggtgtt agtggttttt
    12361 ttaatatgtt ggggcatctg gaaattttca aggctatcaa tccttactat gctctgcatt
    12421 tgctgtttag tcctgaaaac catcgtggga tttttatctt ggggtccatt tttcttgcga
    12481 caacaggagc tgaagccctt tattcggatt taggacatgt tggtcgagga aatatttatg
    12541 tgagctggcc ctttgttaag atgtgtattg tgctgtctta ctgtggccag gctgcgtgga
    12601 ttttagcgaa taaacactca ggtattgaac taaacccttt ctttgctagt gtgccatcac
    12661 aattaagggt ttaccttgtt agtttggcaa ccttggcagc tattattgcc tcacaggctc
    12721 ttatttcagg ctcctttacc ttggtttcag aagccatgcg tttgaaaatt ttccctttgt
    12781 ttcgtgtgac ttacccaggg gcaaatttgg gacaattgta tattcctgtc attaactgga
    12841 ttttatttgc agtgacctct tgtactgttt tggcttttag aacatcagcc cacatggagg
    12901 cagcttatgg tcttgctatt accatcacca tgttgatgac aacaatcctc ttaaagtatt
    12961 acttaatcaa gaaaggaacg agacccatct tggctcattt agtgatggct ttctttgccc
    13021 ttgtagaatt cattttcttc ttggcttcag ctatcaaatt tatgcacggt ggctatgcgg
    13081 ttgttatctt ggcacttgca attgtctttg tcatgtttat ctggcatgcg ggcacacgga
    13141 ttgttttcaa gtatgtgaaa tctcttaatt tgaatgatta caaggagcag attaaacaac
    13201 ttcgtgacga cgtttgtttt gacctctacc aaacaaatgt tgtctaccta tccaatcgta
    13261 tgcaggatca tatgattgac cggtctattt tatactccat tttagacaag cggccaaaac
    13321 gcgctcaagt ttattggttt gtaaatgtcc aggtaactga tgaaccttat acagctaagt
    13381 acaaggtaga tatgatggga acggattata tggttcgagt caacctttat cttggtttta
    13441 gaatgccaca gactgtgcca cgctatttgc gcacgattgt tcaggatttg atggaaagtg
    13501 gccgtttacc caaacaagaa caggaatata ccatcacacc tggtcgtgat gttggtgatt
    13561 ttcgctttgt tttaatagaa gaacgggtct ccaatgcacg tcaattgagt aactttgaac
    13621 gctttattat gcagactaag gcaagcatta aacatgttac cgctagtcca atgcgttggt
    13681 ttgggcttca atattcagaa gtaacccttg aagtggttcc cttgattcta tcagatgtct
    13741 tgaagttacc aatcaaagaa ttggtgcctg tggaagacag tgaagcataa aaaaatcatt
    13801 gagatgataa gtctcaatga tttttctttt ctttttgatg agtagcaata taggccaatt
    13861 tctggcttct tgtttttcgt tttttaaaga gtgcttcagc gctcatcgca gcctctttgc
    13921 tatcaaacac ttcgtaataa agtaaagaaa caggtaaccg gtagcgagta tatttagccc
    13981 cctttcctgc gttatgtgta gctaagcgtt ttttcaaatc agttgtataa ccagtgtaga
    14041 gggttttatc aacacattct aacacataca tataagcttt tttagtggtc atgattaggt
    14101 tttcctttgg aagcagcacc aaaataaatc tcaaaaatat gatcagtgta ttctccgttt
    14161 tccttgtgga caactaaagg aggtaaaata gtcatccctt caatagaacc gtctttgatt
    14221 gcttcaataa gtaacatatt agctgattta cctaatttag gatagacaaa ttgtaccctt
    14281 ttaggggcaa gaccattagc tctaaggcta tctataattt ccaagaatcg atctggtcga
    14341 tgaaccattg ccagacgacc atttgattta agggcatgac gggctacctg acaaatctct
    14401 tctaaattag tggtcacttc atgacgagcc agtaaataat gttcagagac gttcttctta
    14461 gaactttcgt gacttttaaa gtaaggggga ttgcagagca tcaaatcaac tcctgaacgt
    14521 ggcacatggt ttaggaggtt ttttaaatca tcacaaatca tggttacttg gtcttccagt
    14581 tgattgagct ggatagagcg ttgtcccata tcagcaagcc gttcttgtaa ttcgacctca
    14641 atgatggctg ccttggttct agtgctagca aataagccaa ccgccccatt tcctgagcac
    14701 aaatccacaa ttaacccttt ggaaggcatc ttggggaagc gggataagag gacgctatca
    14761 atagagtaac taaagacatc cttgttttga ataatgccaa catcacttga aaagagttga
    14821 tcaatacgtt cgccttcttt taagattgct tttatcatac ctgttatttt aacataaaat
    14881 aggcttgagg tgaatgtttg aagagtgatt ttgactttcg aaaagtcagc tttcatgata
    14941 caataagtaa gattattcta ttaaaggaga agcctgtgtt ttacgcttac ttacgcggtt
    15001 tagtagtctt tttattatgg gttgtcaatg gcaatgccca ctaccatcat gaagaaaaga
    15061 tgttagatgc ttctgagaat tatattctgg tagcacccca tcgaaccttt tgggatccag
    15121 tttacatggc atttgcagca cgtcctaagc agtttatttt tatggctaaa aaagagttgt
    15181 ttgcaaatcg tctctttgct tggtggatta aaatgtgtgg tgcttttcct attgatcgtg
    15241 acaaaccgag tccagatgct attcgttacc ctgttaatat gctcaaaaag agcaatcgtt
    15301 ctcttcttat gtttccaagt ggaagtaggc attcgcaaga ggtcaaagga ggggtcgctg
    15361 tgattgctaa attggctaag gtcaagatta tgccagcagc ctatcagggg cctatgtcgg
    15421 tcaagggatt actagcggga gaacgggttg acatgacttt tgggaatccc attgacgtct
    15481 cagatattaa acgcatgaat gatgaaggga ttgctgaggt ggcaaaccgt attcaggcag
    15541 agtttgatcg gatggatgac gagttggcac ctttccaacc aggaaaagca aggaaccctt
    15601 taacttatct ctaccgttta ccattaggat tggttttggt ggtggtatta ttattaacca
    15661 tgttattttc ctatattgct agttttgttt ggaatccaga taaacatcgc cattaagaac
    15721 atgagggcta acatgtgcct gaaataagaa gtgattgaga ttagtcttct attgaaagaa
    15781 gccgctaatg cttaatcact tttttcattt ctaaaaaaga tattcgatga tacccttaac
    15841 tcttttaagc acaaaaaatg acaatactac tatacttttg gatatcattt acgaataaaa
    15901 agatgaggta aaaaaatgtt agacgaatta ttaattaaag gaaaatcgtt tttgagagag
    15961 cggtattttc tgccatacct aattagtctt ttattaggac tttttctaat actaagcttc
    16021 agttttttgt tctggggaaa taggcagagc aaggcagccg ttcctgcttt gagagaaata
    16081 tcgcctgtga aacagcaggt tagtgaagaa aaaaaggaaa ttcaagaaga tagcagtatt
    16141 ttagtggatt taaaaggcgc cgtacaaaaa gagggagttt ataagctaac tgctagcagt
    16201 cgtgtgcgag atgtcattga actagctgga ggcctaactt cagaagctga taaacatgct
    16261 attaattttg cagaaaaact aactgatgag caagttgttt atgtacctaa acaaggagaa
    16321 gagatttctg tgctaccaag atcattagtt tctggtaaaa aagaaactgc cagcaaggat
    16381 cagtcaaagg ttcatattaa taaggccagc ttagaagaac tacaacatat cccaggtatt
    16441 ggtgctaaaa gagctcagga tattattgat atgagagata agttaggtgg ttttaaagcg
    16501 ttagaagatc tccgtcaggt ttcggggatt ggcgaaaaaa cgctcgagaa attaaaagat
    16561 gacattttct tggactaagc tagtgcccct gtcaaagatt caatttgctt ttttaatctt
    16621 ggttctcttt tatcaaatcc atagccctag ctggttaacg tttctcctta gccttagttt
    16681 gatttgctta cttgtcaagc gtttgtctaa aaaagaattt ctcggtgtct ttgccatcct
    16741 tagtttctgt gctttgtttt tgctgtatca gaaacagcag ttgattcaaa aactggaaat
    16801 tcagccagta caaataacct ctgtagcatt agttcctgat agtattcgga ttaatggtga
    16861 tcaattagct gttcttggac gtcacgggaa acattcttat cagttatttt accgtttgaa
    16921 aagccaagca gaagcccaat tgttcaagaa agagcaccgt tggttagtga tgcacgcaaa
    16981 agtgacattg gaaaaagctg aggaagttcg aaattttaaa ggctttaatt atcagacttt
    17041 tttggcttat caaggaattt acaggatagg gaaggtagag caaatagaac agcttgaagt
    17101 gatttcaccc gagtcaatat gtgactattt gtcctcttta agacgacgag ccattgttca
    17161 ttgccagcag cattttccaa gacctatgtc tcactacctg acgggcctcc tttttggtta
    17221 tttagataag tcgtttggtg agatgacaga ttattatagt cagttgggta tcattcatct
    17281 ctttgcttta tcagggatgc aggttggctt ctttcttact tgttttagaa gggtgttgct
    17341 attactcgca gttcctttgg aatggataaa atggatagag cttccttttg cttgctttta
    17401 tgccgcgttg acaggttata gtatttctgt tattcgaagc ctcgtgcagt cgcagttgcg
    17461 tcatttagga ataaaaggat tagacaatct ggcttgtact tttttacttg tctttttatg
    17521 ggatgctcat ttcttaatga ctgttggtgg cgtattaacg tttagctatg cttttttgtt
    17581 aacagtggtt actgttgaag aattatcagg agctaaaaga cagttggtac aagtcttgac
    17641 catttcccta ggaatattac catttttgct cttttatttt tctagtttta accccatgtc
    17701 aatggtctta acagggctct tgtcttatct ctttgacctt tttattttgc cccttctttg
    17761 tctggttttt tgtctatccc ctttggtgac tgtctcaata tgtaaccatc tttttatttt
    17821 attagaaaaa gtcattcaat ttctcggaaa tactttcaat agttcccttg tttttggaag
    17881 cccgaccagt tggcacttgc ttatcttggt gattagcttc gctatttttt atgattatcg
    17941 gcaggtgcga caacgagtta tcacttgcgg tttggttata gcgttgacgc ttttgtctgt
    18001 caaatatcct ttgaccaatg aagtgacctt tatcgacatt ggccagggag atagtatttt
    18061 ggtgagggag tggacaggga aaaatctctt aatagatgta ggtgggcgcc ctttcttttc
    18121 ttcaaaagag cactggcgac gaggacatca cgtagctaat gctcagaaaa ccttaattcc
    18181 ttacttaaaa agtagaggta ttcacacaat tgaccaacta ttagtaactc acgcagatac
    18241 tgatcatatg ggggatatcg aagtggttgc caaagctatt cgaataaagg agattttgac
    18301 tagtcaaggc agtttaagcc atccaagctt tgttaggcgg ctaaggcgtt taaaatgtca
    18361 cgttagggtt ttagcagctg gagaccagtt gcctattatg ggaagtgtct tacaggtact
    18421 ctacccttgg cagttagggg acgggaaaaa taacgattct ttggtacttt atggcaggct
    18481 cttaaatcga acttttcttt tcacaggtga cttggaaaaa gagggggaaa acgagatcat
    18541 aaaacgttat cctcaactaa gagtagatta tttaaaagca ggtcaccatg gatcaaatac
    18601 ctcttctagt gcagcttttt tagaccatat tcagcctaaa gtggccttta tttctgctgg
    18661 aaaaaataac cgttatcagc atcctcacag agaaacctta gcccgtttgg aagacagaca
    18721 aattacttat taccgaacgg atacgcaagg agctattcgt ttgactggtt ggacaagctg
    18781 gcatcttgaa acggtccgtt agttaaaatt ccagcctgac gaagaaacaa gcagtcgctt
    18841 tccttttagg agaaagatga tataataaaa gcatgattgc gatagaaaag attgaaaaac
    18901 tgagtaaaga aaatttgggt cttataaccc ttgtcacagg agatgacatt ggtcagtata
    18961 gccagttgaa atcccgctta atggagcaga ttgcttttga taaggatgat ttggcctatt
    19021 cttactttga tatgtctgag gccgcttatc aggatgcaga aatggatcta gtgagcctac
    19081 ccttctttgc tgagcagaag gtggtcattt ttgaccattt gttagatatc acgaccaata
    19141 aaaaaagttt cttaaaagaa aaagacctaa aggcctttga agcctattta gaaaatccct
    19201 tagagactac tcgactaatt atctttgctc caggtaaatt ggatagtaag agacggcttg
    19261 ttaagctttt gaaacgtgat gcccttgttt tagaagccaa ccctctgaaa gaagcagagc
    19321 taagaactta ttttcaaaaa tacagtcatc aactgggttt gggatttgag agtggcgctt
    19381 ttgaacaact gcttttaaaa tcaaacgatg attttagtca aatcatgaaa aacatggctt
    19441 ttttaaaagc ctataaaaaa acgggaaata ttagcctaac tgatattgag caagccattc
    19501 ctaaaagttt acaagataat atttttgact taaccagact tgtcctagga ggtaaagttg
    19561 atgtggctag agatttgatt catgatttac gcttatcagg ggaagatgat attaaattaa
    19621 ttgctattat gttggggcaa tttcgcttat atttacagct tgccattctt gctaaagaag
    19681 gaaaatcaga acagcagctt gtaaccagtt tgtcagagat acttgatcgg cgggttaatc
    19741 cttaccaggt caagtatgcg ttaaaggatt ctaggacctt atctcttgcc tttctaacag
    19801 gagcggtgaa aaccttgatt gagacagatt accagataaa aacaggactt tatgagaaga
    19861 gttatctagt tgatattgct ctcttaaaaa tcatgactca ctctcaaaaa taggcgttgg
    19921 accgctttcc aagagataat caaattagtt gaaagctctt attttttgcg ataagataga
    19981 cgtatcataa aggaaaagag gacaggaaaa tggctattat tttaccagaa cttccatacg
    20041 cgtatgatgc tcttgaacca cagtttgatg cggagacaat gactcttcat catgataaac
    20101 accatgccac ttatgtcgct aataccaatg cggctttaga aaaacaccca gagatcggag
    20161 aaaatctgga ggaactattg gcagatgtca ctaagattcc agaagatatt cgtcaagcct
    20221 taattaataa tggtggcgga cacctaaacc atgcgctttt ctgggaacta ttatcacctg
    20281 aaaaacaaga cgtcactcct gatgttgcac aagccattga tgatgctttt gggtcatttg
    20341 acgcctttaa agaacaattt acagcagctg ctactggacg ttttggttca ggttgggcat
    20401 ggttagttgt taataaagaa ggacaactcg aaatcacatc aaccgctaac caagatactc
    20461 caatttcaga aggcaaaaaa ccaattctag cgcttgatgt gtgggagcat gcttactact
    20521 tgaattatcg taatgtacgt ccaaattata tcaaagcttt ctttgaaatc attaattgga
    20581 aaaaagtatc agaactttac caagccgcta aataagaaaa gggtttccaa tctcaaaaag
    20641 agattggttt tttaagtggt tttgtgaata acagtgtggg gacatcattt tttagaaaag
    20701 ataaaaatag tttgtctttt taatgtaatt ccttgatttt tagctaaatt tagctagaat
    20761 agaatggata ggagatttta ggtgttaaga aagaagaaaa ctaccattgt agggattatt
    20821 ttaggaatga tgatagtgac cttacttgtc ggctgtttga ctggtaaaaa gaaaggcttt
    20881 cctcctaaag caggtgagcg gcagcaaacg gctgacttaa aaatgaaaaa agattagaaa
    20941 aactgttcaa aaaccgttac ctgaaaaatc taaagaggct aagcaagctg ttatggatgc
    21001 agatttagcg caaatggatg ccttagggct ctattacgat gacaaccatt tgagtttggt
    21061 caatacggtc aaggtgtatt taaaggaatt tggcattggt gaatctcaaa ttgccttttc
    21121 ctacaaagac ctcaattcag gcaggactgc tgccatgaat gaccatcagc caatgattgc
    21181 aggaagcacc tataagctgc cattaaacat gctggtggta gataaggcaa attatccatg
    21241 acagagcgtt ttgacattac agaaactgat tatgaatatg atcaggaaca tcatgcctat
    21301 gttgctcaat tcaatggtgc catgtctatt ccggatatgc aagaatattc cttggtgtac
    21361 tcagaaaaca cgccagctta tgctctagca gaacgattgg gtggcatgaa taaggcttac
    21421 caattatttg accgctacgg gaaggtatcc ggggctatta cgaccattga tcgtaatggc
    21481 aataaaatca ccaccgctta ctatttgcaa ggtttggatt acttgtggca gcatcaggat
    21541 aaatataagg atatcttgta ctacattggt gaatctttcc ctgatttgta ttacaagact
    21601 tatttgcctc atgtaaaggt ttatcaaaaa ccgggttatg tcagagaagc cttaaatgta
    21661 ggtgccattg tttgcgaaga gtctccttat ttgattactc tttattcatc tggtttaggt
    21721 ggagcaacac aagcatcaga ggaagtcaat ggccttggtt atgtgcagct tgttcagcta
    21781 acatatgtaa ttaatgagtg gcatagagtc aatcacaaca tgatctaata ctcagttgac
    21841 attagtctga tagtagacat acttactgat gaaagtcact aaaataagtt tttgctcatt
    21901 aaaaaagctt ggcctgtttc ttcaggtcaa gctttttgag attaatgctg tgtttttgag
    21961 gtcttattgt cacctcttgt ttcttgataa tggtgaagca attttttgaa ttttttaacg
    22021 gcagcgcgtg ttagctgctt agatgatttg ccatttctgc tgtaaatggg attgtgctta
    22081 tccctttgct gttctaaatc gggaactaga aaagttgcat caggactatt aattgctttt
    22141 tcaataaaag ccggatcaaa aagcagaata gggtcaatat caagcagacg gtgcaagtca
    22201 tcgttttggt tgccataatt gaaagaagaa ccattgacaa tactatttcg cgttaggtta
    22261 tcaggatcta gtgctactaa aaattgtcca gattctgaca aaataaactc tgagtgaaaa
    22321 tgaattaaaa tcttatagtt ggcttgagga atattgtctg tatagactgc ctgatgattg
    22381 ccattagcat ctaaaatact agcaacctta ttatggtatc tagaagattc ataaagagca
    22441 taatcgtcat cttctagagt agccaaatat ttggctaagg catccgcatc ggttttccct
    22501 ttattcccat aatgtgagcg aacccactcc gtttgctggg ttgatatgag gtaacggagt
    22561 tgatgaattt tccgattaaa acggctataa ggaatgtgtt cgagattaac ataataagcc
    22621 tgaatcaggg tagataattg gtcccaaaaa ggatctgttg gcgatagctt tggacttaat
    22681 tgtgccaata cttgctgtgt ttgttttgat tgtcctgtca actcgtctgg catctttaaa
    22741 tacgtcaaga gcagttgtaa ccgtttttga gcttcttgag gcgtctgtgc catctcttct
    22801 tgttgccaaa gcttttgaaa gtcaggtgat cctatcaggc gaatgcgact ataaagttgt
    22861 tcgaaatgat aagagtttcc tctaacagcg agttgttcaa ggtatccttt ttggatggct
    22921 ttataggacc atccgtcctt atcgagcttt cgaacataat caagcaagtc gtggcgtaat
    22981 ttaatagctt ctgaaagctg gagttctcgt aatttaggat agttttggta aaaaggtgcc
    23041 actaaatttt gataaagttt gtgttctttt tcaaaggcaa tccgctgata gtctttctgc
    23101 caaaaactga cgcaaaaagt cagaaacatc aagaagaata gccattttcc aagtaatttc
    23161 ataggttttt agttgacaaa catggcatcg ccaaagctaa agaaacgata cttttcgtca
    23221 accgcgtgtc tgtaagcttc aaggacaaag tcacgccctg caaaggctga tactagcatc
    23281 acaagggttg attttggaag atggaaatta gttgaaaaag catcaactac cttgaattgg
    23341 tagcctggtt taataaaaat attggtccaa cctgaatcag cttgaatgtc cccttggaac
    23401 ttacctccga tggtttccaa cgtacgaata gaggtggttc ctacagcgac aacacgaccg
    23461 ccagcttgtt tgacgtctct tagggtttgc gctgcttctt ctgagaggga ataaaattcc
    23521 gaatgcatat catgctcatc gaggttatcc acggaaacag gtctaaaagt cccaagccct
    23581 acatgtaggg tcaaataaac caaatgtacc cctttggctt cgattttttt gagcaagtct
    23641 gttgtgaagt ggagaccagc agttggggcg gccgcagagc cattttcttt agcataaacg
    23701 gtttggtatc gctcagcatc ctctaatttt tcgtgaatat aaggaggcaa tggcatttcg
    23761 ccgaggctct ctaaaacttc taagaaaatc ccatcatagc tgaattcaac aattcgtcca
    23821 ccatgttcta attcgtcgat aatggtggct ttgagacgcc catctccaaa attgacttgg
    23881 ctaccaacct tgagccgttt ggctggcttg gctaaaactt cccattgatc tccttgtgta
    23941 tttttaagca aaagcaattc cacatgacca tgagtatcgg gtttttctcc ataaagtctg
    24001 gcaggcaaga cacgggtgtt attcatgacg agggcatccc ctggatttaa ttgatcaatg
    24061 atatggtcaa aatggctatc aaccatagtt ttttgacggt gatcaataat caatagtttt
    24121 gaactgtctc ttttttcgag tggggtttgg gcaatcaatt cttctggtaa ctcaaaatca
    24181 aaatcgttag tattcattgg gactccttta aagccactag taaatctctt cctagtaact
    24241 ctttcatgta agataaatct tttctattat atcacttgtc gtctaacccg tcatctttaa
    24301 tctttcatca gaaagtaaag gataggcttg acaaaaattg gtatatacca tataataaaa
    24361 acacgaaagg tctataccaa ttagaaaagg agaatgacat gaaaattatt cgggtccaag
    24421 atcagattga aggtgggaaa atcgctttta ccttattgaa agatagctta gctaagggag
    24481 ctaagacgtt aggattagca acaggaagtt caccaattag tttttaccaa gaaatggtca
    24541 aaagtccttt ggatttttcg gacttaacaa gtattaactt ggatgaatat gtcggtcttt
    24601 cagtagagag cgatcagagt tatgattatt ttatgcgtca aaaccttttt aatgcgaagc
    24661 cttttaaaaa gaattacttg cccaatggtt tagcaactga tatcgaagct gaagctaaac
    24721 gatatgacca aatcattgca gggcatccga ttgattttca agtgcttggg attgggcgta
    24781 atgggcacat tggttttaac gaacctggga cctcttttga agaagaaacg catgtagtgg
    24841 atcttcagga atcaactatc aaagccaata gtcgtttctt tacaagtatt gaggatgtgc
    24901 caaaacaagc tatctctatg ggaattgcct ccatcatgaa gtccaaaatg attgttcttc
    24961 ttgcctttgg acaagaaaaa gctgatgcga tcaagggaat ggtttttgga ccaatcacag
    25021 aagacctccc agcaagtatt ctccaaaaac atgatcatgt tatcgtcatt gtggatgaag
    25081 ctgctgcgtc acaattagat taacctaacc agtcgttaaa ccttgtaaga acaaaaatga
    25141 ggagatagtc aacctcattt aagaagaagt cttgtaactt ctatttcttt tgcaagggta
    25201 aatttatgtt acactactaa tatgcgttta gataaattat tagaaggtac aaaagttggc
    25261 tctagaagtc aagtgaagaa actgattaag gctcaagggg tttgggttga tcacatgcct
    25321 gccagaaatg gtcgacaaaa tgttgatcct ggcttgcaac tgattgaggt gactggacag
    25381 cgagtgacgc atcctaaaca ttcctacatt atcctcaaca agccatcagg ggtggtctca
    25441 gctaagaaag atactaacta tttaaccgtt attgatcagc ttgctgaaga agataaaagt
    25501 ccagacttgt atcctgttgg cagattggat agagataccg aagggttggt tttactcact
    25561 gataatggtc ccctagggtt tcggatgttg caccctattc atcatgtttc taaaacgtat
    25621 cttgtaaccg ttaatggctt gttagcagaa gatgcctcag atttttttgc agctggtatt
    25681 tgtttcccaa caggtgaaca atgtcaacca gctcaattga ctattcttaa agccgacaca
    25741 gaccagtcac aggctagttt gaccatttca gaaggaaaat ttcaccaagt gaaaaaaatg
    25801 tttttgacct atggtttgaa agtgacctct ctgaaacgga cgcactttgc aggattggaa
    25861 ctcggtcatt tagccagcgg agaatatcgt tatctaacag cgtcagaaag gcaactcatt
    25921 aaaacgtatc tagactgagc aaaacatgct ttcaaaaaga agctattctt gcttaatcaa
    25981 taaagtgtcc attgactatt atagtcatga tgagtccgac ttttgctatg tttagtcatc
    26041 ttgttgttac aaaatcaggt aagcaaaaaa attcaattcc cactgtctcc ttaacctgaa
    26101 gcgttataaa aacccttgtg ttaaactctc ataaattgga aatgggagtg ttttttgatg
    26161 gctaaaaaaa ctaaagctac ttaaagtttg gtacttagtt ttcgaataat aaggtggaag
    26221 atctaatagg aggtgacaaa aatattaacc gctttagatg gtaagaatca gctcatttcg
    26281 ctagtaactc agcctatttc aacgaaaccg cctttttgtt gcccagcttg caaatctcct
    26341 gttcgcttgc gtcaggggac aattagacga cctcattttg cccatgtaca actagctcat
    26401 tgtcaattcc aagcagaaaa tgaatctgag gaacatttga cgttgaaggc aaaactttac
    26461 accagtttag tccgaacaga agctgtctgt attgaaaaat atcttcctga gctgcaacag
    26521 atagcagacc tttgggtgaa tgataagtta gccttagaaa ttcagtgcag tcccttgcca
    26581 gttgagcgtc taaagaaacg caccaaagcc tatcaagaaa aggggtatcc ggtacgatgg
    26641 ttactgggaa gaaaattgtg gcttaacact cacttaactg ctttgcaaaa acagtttctt
    26701 tacttttcat ctagtttggg ctttcatttg tgggagctgg atgcagctgc aaatctgcta
    26761 cgtctcaaat atttaatcca tgaagactta tttggtaagg taagttacct aaccaaaacc
    26821 atttctttag accacaatat tatggaaatg tttcgattac cctatcagca agaaatcctt
    26881 tattcttatc agaaaaaaat gactgtgaac ctatctaaaa gaatacaaag agctctttta
    26941 gctagacacc cgaaatggct acgacgacaa gaaaaggctt acttatcagg ctataattta
    27001 cttatgttaa caactgatgc tttttatcct caatggagac cagttcaatc ttccagcggt
    27061 ttttgtcaaa ttgaaggaaa tcttcgccct tattatgaaa gttttaaagt ctattataaa
    27121 aaagaaaagg ataagaaggt gcaaacgctt ttttcaccaa aatattatgt taaaatggat
    27181 agtaatagaa aatgagaagg agatgttatg actgataatc gcagccattt agaagaaaaa
    27241 tacacttggg atttgagcac tatttttgca acagataagg attgggaagc tgaagtcagt
    27301 gacttagcta ctgaaattga cgcggctaag gatttttcag gtcatttact agattctagc
    27361 gctaatctgt tgacaattac agatacttat ttagagttag ctcgtcgtgt tgagaaagtc
    27421 tatgtttatg ctcacatgaa aaatgaccaa gacactactg ttgccaagta tcaagaatac
    27481 caagctaagg cttcaggctt gtatgcaaag tttagcgaag tgttttcatt ctatgaccca
    27541 gaagttatgg cattgagtca ggaagattac caagcttttc ttgcggaaac acctgattta
    27601 aaaaggtatc atcatttctt tgacaaattg ttccagacac gtgaccatgt gctcagccag
    27661 gctgaagagg aattattagc aggagcccaa gaaattttca acggcgctga agaaaccttt
    27721 agtattcttg ataacgctga tattgtcttt ccagtagtta aaaatgataa gggggaagat
    27781 gttgaattaa cccatggtaa cttcattagc ctaatggaat ctaaggaccg tagcgttcgc
    27841 caagctgctt atgaagccat gtatagtact tatgaacagt tccaacatac ttacgctaaa
    27901 accttgcaaa ccaatgtgaa agtgcaaaac tataaggcgc gtgttcataa atacgattca
    27961 gcacgtcaag ctgccatggc tgctaacttt attccagaag ctgtttacga cactttatta
    28021 gaaacggtta acaaacattt accactctta caccgttatt tgaaattgcg tcaagaggtt
    28081 cttggtttag acgatttgaa gatgtatgat gtttacacac cattatctga aacagatcta
    28141 gccattggtt atgatgaggc tttggaaaag gctgagaagg ttttagctgt ttttggtaaa
    28201 gattacgcag atcgtgtgca tcgtgctttt accgaacgtt ggattgatgt tcatgtcaat
    28261 aaagggaagc gttctggagc ttattcgggt ggttcctatg ataccaatgc ctttatgcta
    28321 ttaaactggc aagatacctt agacaatcta tacactttag ttcatgaaac tgggcacagt
    28381 ttgcattcta ctttcactcg tgaaacacag ccttatgtgt atggagatta cagtattttc
    28441 ttggcagaaa ttgcatccac aacgaatgaa aatattatga cagaagctct cttaaatgag
    28501 gttcaagatg agaaagaacg ctttgccatt ttaaaccatt acctcgatgg tttccgtgga
    28561 acagttttcc gtcaaaccca atttgctgag tttgaacatg ccattcatca agctgatcaa
    28621 aaaggagaag tgttaacaag tgaatacctt aaccagctat acgctgattt aaatgaaaaa
    28681 tattatggtt taagtaaaaa agataatcat tttattcagt atgaatgggc acgtattcct
    28741 catttctatt acaattatta tgtttaccaa tatgcaacag gttttgcagc tgcaagctat
    28801 ttagcggata agattgtgca tggcacacaa gacgatatcg atcattactt ggcctacctc
    28861 aagtcaggaa attctgatta cccacttgaa gtgattgcta aagcaggcgt tgatatgaca
    28921 aaaggtgatt atttggaagc cgcctttaaa gtctttgacg aacgtctaac agaacttgaa
    28981 gtactcgtgt ccaaaggcat acacaaaagc taaaatcaca aaagtcaagg acaaaaagag
    29041 tttaggattg atagaaatgg agattcacag ttggtgtgaa tctccatttc tatcggtcat
    29101 tttcttttta tattttagtg gattatcagt cctgaaaagc aggcttcatt gaccttagtt
    29161 tgacggtttc ttttttgtct tttttattgt gtggtcactc acttaaataa aactaatagt
    29221 tgagtaaggc gcttcagatt aacgctattc tattgcttta gagataacgt tcgcataaaa
    29281 catattttta ttatatttga cattttataa aagagataat agaattaaaa tactaacatt
    29341 tatgtttttt aaaaaataaa cgttcgtata ataaaaaagg agtttttcat ggaaaaaaca
    29401 aaacgttata tcattgcaac agcagggata cttctccact taatgttggg atcgacctat
    29461 gcttggagtg tttatcgtaa tccaatttta caagagaccg gttgggacca agctcctgtc
    29521 gcttttgcct tttctttagc tattttttgt ttaggtttat ctgctgcttt tatgggaaat
    29581 ttagttgaac aatatggtcc tcgtctaacc ggaacggtgt cagctattct ttatgcttct
    29641 ggaaatatgc tgactggttt agcgattgat cgtaaagaaa tttggctttt atatattggt
    29701 tatggtgtta ttggtggctt aggacttgga gcgggatata tcacaccgat atcaactatt
    29761 ataaaatggt ttccagataa aagaggcatg gcaacagggt ttgctattat ggggtttggt
    29821 tttgcgtctt tattaacaag tccgattgcc cagtggctaa ttgaaacaga aggtttggta
    29881 gcaacatttt accttttagg gctgatttat ctaatagtta tgctttttgc ttctcaattg
    29941 ataataaaac caactgctgc tgagatagct atactagata aaaaaagatt acaaaataac
    30001 agttatttaa tcgaaggaat gaccgctaaa gaagcactta aaacaaaatc attttattgt
    30061 ctttgggtaa ttttatttat caatatcaca tgtggcttag gacttatctc agttgttgcg
    30121 ccaatggcac aagatctaac tggtatgagt ccagaaatgt cagcaattgt ggttggtgct
    30181 atggggattt ttaacggttt cggtcgttta gtgtgggcta gtttatcaga ctatattgga
    30241 cgccgtgtga cagtaatact tttatttttg gtaagcataa ttatgactat tagtttaata
    30301 tttgcacata gttccctaat tttcatgata agcattgcca cccttatgac ttgttatggt
    30361 gcgggttttt ctctcattcc gccttattta agtgatcttt ttggggcaaa ggaactggct
    30421 acattacatg ggtatatatt gacagcttgg gcaatagctg cattaactgg acctatgtta
    30481 ttatctatca ctgttgaatg gactcataat tatcttctta ccttatgtgt ttttattgtc
    30541 ttatacattt taggattaat ggtagtatta aggttgaaga aatgatgtcc tataaaaaat
    30601 ttaaaagtaa accctagcaa agcctagggt ttttttatat aattaggttt atggttaaat
    30661 catacagtaa aacagcaaat cataatatgc gtcgtcctgt tgtcaaagaa gagcttgttc
    30721 attatatgcg aacacggcag aagcaaacca caggtttttt agcagagtta gagcaattcg
    30781 caagacaaga aaacattcct attattcagc ctgaggtcgt ggcttatttc aggtttttat
    30841 tgcaaagctt acagccaaaa cacattttgg agattggcac agccattggt ttttctgcgc
    30901 ttttaatggc tgaaaatgca ccagatgcga cgattgtgac tattgatcgt aatcgagaga
    30961 tgatcgattt tgctaaagca aattttgcta agtacgacag tcgccaacag atccgcctgt
    31021 tagaaggaga tgcagcagat atattatcta cacttgaagg aaattttgac tttgtgttta
    31081 tggattccgc caaatccaaa tatattgtct ttctaccaga gattttaaga ctgctaaaag
    31141 tcggtggtgt agtcattttg gatgatgtct ttcaaggagg tgacattaca aaaccgatcg
    31201 aagacattcg acgaggtcag cgtactattt atcgtggctt acagtctttg tttgatgcca
    31261 ctttaactca tccaaagcta acaactagcc tggtccctct tagtgatgga ttattaatga
    31321 ttcgtaaaaa tcaagcagat attgtattac cagattaagt aacattgata aatttatgtt
    31381 ataataaatt agttaaagat aaaaaggagc tcagaagtaa atgaaaaact caaataaact
    31441 cattgctagt gttgtgacat tggcctcagt gatggcttta gcagcttgtc aatcaactaa
    31501 tgacaatact aaggttattt cgatgaaagg tgatacaatt agcgttagtg atttttacaa
    31561 tgaaacaaaa aacacagaag tatcgcaaaa agcgatgcta aatctggtaa ttagtcgtgt
    31621 ttttgaagct caatatggtg ataaggtttc aaaaaaagaa gttgaaaagg cgtatcataa
    31681 aacagctgaa cagtatggcg cttcattctc tgctgctttg gcacaatcaa gcttgacacc
    31741 tgagactttt aagcgtcaga tccgctcttc aaaattagta gaatatgcgg ttaaagaagc
    31801 agctaaaaaa gaattgacaa cacaagaata taagaaagca tatgaatctt atactccaac
    31861 aatggcagtc gaaatgatta ctttagataa tgaagagaca gctaaatcag tcttagagga
    31921 actaaaagcc gaaggcgcag actttacagc tattgctaaa gaaaaaacaa caacacctga
    31981 gaaaaaagtg acctataaat ttgattcagg cgcgacaaat gtaccgactg atgtcgtaaa
    32041 agcggcttca agtttgaatg agggtggcat atcagacgtt atctcggttt tagatccaac
    32101 ttcttatcaa aagaagtttt acattgttaa ggtgactaaa aaagcagaaa aaaaatcaga
    32161 ttggcaagaa tataagaaac gtttgaaagc tatcattata gctgaaaaat caaaagatat
    32221 gaatttccaa aacaaggtta ttgcaaatgc attggataaa gctaatgtaa aaattaaaga
    32281 caaagctttt gctaatattt tggcgcaata tgcaaatctt ggtcaaaaaa ctaaagctgc
    32341 aagtgaaagt tcaacaacca gcgaatcatc aaaagctgca gaagagaacc catcagaatc
    32401 agagcaaaca cagacatcat cagctgaaga accaactgag actgaggctc agacgcaaga
    32461 gccagctgca caataagtag gattttattg actaatcagt taaaaaaact tataataatt
    32521 tagttaagaa ttgtttatca aggattagat acagaaaagt gacggttgct gcgagtcatt
    32581 gataattaga taaacatgct acttaacttt acaacaattg atatcgtaaa ttaagaatga
    32641 caagttcatt gaatagaggt ggtaccgcgg ttttcgccct ctgtgagatg gacttgtttt
    32701 gtattgagga ctatttgaaa tcaacgaaag gaatagagta gactaggctg ccaggcttat
    32761 agctgatctc ctagcaagaa agacgagctg tgtcaactgg tgtgattaca ttactagctt
    32821 cagcataaca ctgtttttct tactctttgt atctaaattt ttatgaaaga attatcgtct
    32881 gcacaaatcc gccaaatgtg gttggatttc tggaaatcta aaggacattg cgttgagcct
    32941 tcagctaact tggttcctgt gaatgaccca acgcttcttt ggatcaactc aggtgttgca
    33001 accttgaaaa aatactttga tggttcagtg attccagaaa atccacgtat taccaatgca
    33061 caaaaatcaa ttcgtactaa tgatattgaa aatgttggta aaacagcacg tcaccatact
    33121 atgtttgaaa tgcttggtaa cttctcaatt ggagactatt tccgtgatga agctattgag
    33181 tggggatttg aactcttgac aagtccagac tggtttgatt tccctaaaga taagctctac
    33241 atgacttatt acccagatga caaggattca tataaccgtt ggattgcttg tggcgttgaa
    33301 ccaagtcact tggtgccgat cgaggataac ttctgggaaa tcggtgctgg tccttcaggt
    33361 ccagatacgg agattttctt cgatcgtggt gaagatttcg atccagaaaa tatcggactt
    33421 cgcctcttgg ctgaagatat cgaaaacgat cgttacatcg aaatctggaa catcgttctc
    33481 tcacaattca atgctgaccc agccgtacca cgttcagaat acaaagaatt accaaacaaa
    33541 aacattgata caggtgctgg tcttgaacgt cttgcagctg ttatgcaagg ggcaaaaaca
    33601 aactttgaaa ctgacctctt catgccaatc atccgtgaag tagagaagtt gtcaggtaaa
    33661 acttataatc cagatggcga caacatgagt ttcaaggtta tcgctgacca catccgtgcg
    33721 ctttcatttg ctatcggtga tggtgcgctt cctggaaatg aaggtcgtgg ttacgttctt
    33781 cgtcgtcttc tccgtcgtgc tgttatgcat ggtcgtcgtc ttggcatcaa cgaaactttc
    33841 ctttacaaat tggttccgac tgttggacaa atcatggaaa gctactaccc agaagtgctt
    33901 gaaaaacatg attttatcga gaaaatcgtt aaacgtgagg aagaaacatt tgctcgtact
    33961 atcgatgcag gtagcggtca cttagattca ttgcttgcgc agcttaaggc tgaaggtaag
    34021 gatactcttg aaggtaaaga tatcttcaaa ctttatgata cttatggatt cccggttgaa
    34081 ttgacagagg aattggcaga agatgcaggc tacaagattg atcacgaagg ctttaagtca
    34141 gccatgaaag aacaacaaga ccgtgcgcgt gcagctgttg ttaagggtgg ttcaatgggg
    34201 atgcaaaatg aaaccctagc tggtattgtt gaagaatcac gattcgaata cgacacatat
    34261 agtcttgaat caagtctttc agtcatcatc gctgataatg aacgtaccga agctgtttca
    34321 gaaggtcaag ctcttcttgt ctttgctcaa acaccattct atgctgaaat gggtggacag
    34381 gttgctgaca caggtagaat caaaaatgat aagggtgaca cagttgctga ggttgttgat
    34441 gttcaaaaag caccaaatgg tcaacctcta cacactgtaa acgttttggc atcactttca
    34501 gttggaacaa actacacact tgaaatcaac aaagagcgtc gtttggctgt tgagaaaaac
    34561 cacacagcaa ctcacttgct ccatgcagcc cttcacaatg ttatcggtga acacgcaact
    34621 caggctggtt cattgaacga agaagaattc ttgcgctttg attttactca ctttgaagca
    34681 gtaagcaatg aggaacttcg tcacattgaa caagaagtta atgagcaaat ttggaacgct
    34741 cttacgatca caacgactga aactgacgtt gaaaccgcaa aagagatggg agcaatggca
    34801 ctttttggtg agaaatatgg taaagtggtt cgtgtggttc aaattggtaa ttattctgtt
    34861 gaactttgtg gtggaactca cttaaataat tcttcagaaa tcggtctctt caagattgtc
    34921 aaagaagaag gtattggttc aggcactcgt cgtattattg cagttactgg tagacaagct
    34981 tttgaagctt atcgtaacca agaggatgcc ctaaaagaga tcgctgctac tgtaaaagct
    35041 ccgcaattga aagatgcagc agctaaagta caagctctta gcgactcact tcgtgatctt
    35101 caaaaagaaa atgcagagct taaagaaaaa gcagcagctg cagcagctgg tgatgtcttt
    35161 aaagatgttc aagaagctaa gggcgtgcgc ttcattgcta gtcaagttga tgttgcagat
    35221 gcaggggcac ttcgtacatt tgctgataac tggaaacaaa aagactactc tgatgtgctt
    35281 gttctcgtag cagctattgg tgagaaggtt aatgtccttg ttgcaagcaa aactaaagat
    35341 gtccacgctg gtaacatgat caaagaattg gcaccaattg tagcaggtcg tggtggaggt
    35401 aaaccagaca tggctatggc aggtggtagc gatgcaagta aaattgcaga gctgctagca
    35461 gcagttgctg aaacagtgta aatccataaa aaccaagtta tttagaactt ggttttttat
    35521 atttgaaatg actaccatca taaccttttt gactattatc gttgtcaaaa agaaaaagat
    35581 atgttacaat tatagtaaca aatagacatg aggaggtgtt agagaaaatg acacatggta
    35641 tcaaacttaa gaggcagatt tgcttatggg caagtatcct gactcttttc attttaagtt
    35701 atcatcttat cagggtaatc tggtttggag tacccttgag ttatctggtt ttgggcttta
    35761 caggactagc cttgctgttg aatacttttt cttattttag aaagtaagtt ataagttaaa
    35821 gaagaatgaa ggagatggca atggaggtta ttcttaaaaa tcggctcaaa gaattacgag
    35881 ccagagatgg aattaatcaa acggaaatgg ctaaactggc aggagtatcg aggcagacca
    35941 tcagtctcat tgagcgtaac gagtacaccc catcagttat aattgccatg aaaattgcaa
    36001 aggtatttca ggaaccagtt gaagaggtgt ttcgtctagt ggaggtcgag gaatgaaaaa
    36061 gaagaagaat agttttttac gcttgttaaa aatgttattg ctatcaagtt tggcgggagg
    36121 gattataggt ggcatggttg gagccttttt aggttaccat ggagagagat tagatcagct
    36181 cacgttccta aaagatgatg tgattaacct gattatctta ttaaatcgtc tagtagttgt
    36241 cacaggcctc acactttcct ttgttttttt aacgcaactg aaaaaagaga cagctgttta
    36301 taacacaatt gaagaggatg attattctga aaatggttac cgtcagctga ataaaaagca
    36361 tgcttatacc atgttattga ttgccgtagc ttctatttta tccatgtgca atgtgctact
    36421 tggtctgacc ttaactaatg attcacagca tgccatgctg gccattccgc ttctggatat
    36481 ccttttatta ttaatggtca ttccttttca agctttagcc atgaaacgtt acaatgccat
    36541 tcggggaacc gatgttcctt attttccaaa tttgaaagaa ttaaaacata atatcatggc
    36601 tctagatgag gcagagttac aagcctatca taagacatcg tttgaaagtg tgttgtcatt
    36661 aaatggagtc atcatccctt ccttgtatgt gattttattt tttgtctatc tattcactgg
    36721 tcaagtggag ttaacagcca tcttagtttt ggtgttaatt cagctctatt tactcgttaa
    36781 gagtgcaaca atgaccagac aattttaccg ttagcctaaa aggagactgt ttatgaaagg
    36841 attcattaat tatttaaaaa tagcagtgct cattattctg gctatggttt tcaatgtcct
    36901 tccgatgatt ttattgcaaa agcaacacga tattcctatg gtgcttaatt ggggaattgg
    36961 tattttctac ttggttattg ttggaagtgt ccttattgta ttatggcgtc tttatcaagc
    37021 taagcaagac acccctatta aacagcaaaa aatgagattg gttgactggg gttatttagc
    37081 attattttgg ttaatcatcc gtgtgatagc tattgcaggt acccttgtta accagctatg
    37141 gtctggtcaa caagtgagtg ctaatgatgc tgcaatacat accttagcta gacttatcaa
    37201 aggtggtttc ccgctttata ctgccctatt tgtacttgtg atagctttta tcgctcctat
    37261 tatggaagaa ctagtcttta gaggatttcc tatgattgat ctcttcaaag gaaaatcact
    37321 taaggtggca ggtttagtga cctctcttgt ttttgcttta ccacatgcca ccaatagtgt
    37381 tgaatttatc atgtacagct gtatgggcat ttttctcttt gttgcctatc aaagacgagg
    37441 aaacttaaaa gacgctatct tgttacatat ttttaataac ttgattgaag tcattttgtt
    37501 aatgtcaata ggcttaggag tcatataata aaaagcttcg aatggatgaa ctgcacccca
    37561 aaagttggac aaaaaaatct aacatttggg ttggaattgt caagaaaaaa tagacataaa
    37621 gttaagctaa tgagtaacta
//
LOCUS       DAUGUF010000019        36765 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUGUF010000019 DAUGUF010000000
VERSION     DAUGUF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36765
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.019"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(376..1502)
                     /locus_tag="VIB71_000933"
     CDS             complement(join(376..1268,1268..1502))
                     /locus_tag="VIB71_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8822679.1"
                     /translation="MSTVKRYDEEFKQSLVNLYQTGKTQSELCKDYGVSASALAKWIK
                     QYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLIPKKSKCHIHAKLKVRLLAVYRLRF
                     EHATTTLCRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKV
                     ILQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPN
                     QVWSTDFTYISIGYKKYVYLCAILDLYSRKCIAWKLSHHMDAKLACDTLELALNKRKI
                     EGTLLFHSDQGSQFKARKLRKIIDDNTIMHSFSKPGYPYDNAVTEAFFKYLKHRQINR
                     KKYQNIKQVQLDCFEYIENFYNNYNPHTANLGLTPNQKEEN"
     gene            1806..2603
                     /locus_tag="VIB71_000934"
     CDS             1806..2603
                     /locus_tag="VIB71_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8822680.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYHGEILFADMMTKEQYTEVAKKVLANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            2607..3431
                     /locus_tag="VIB71_000935"
     CDS             2607..3431
                     /locus_tag="VIB71_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ8822681.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            3431..4981
                     /gene="ftsY"
                     /locus_tag="VIB71_000936"
     CDS             3431..4981
                     /gene="ftsY"
                     /locus_tag="VIB71_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEQ8822682.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEVVQQEDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHSSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KEVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(5036..6403)
                     /locus_tag="VIB71_000937"
     CDS             complement(5036..6403)
                     /locus_tag="VIB71_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8822683.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFNWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSLILFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            6731..7573
                     /locus_tag="VIB71_000938"
     CDS             6731..7573
                     /locus_tag="VIB71_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEQ8822684.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLIVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            7575..9437
                     /locus_tag="VIB71_000939"
     CDS             7575..9437
                     /locus_tag="VIB71_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ8822685.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKSISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGAATIVLAFSLTWFMGIDEE
                     SPEQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GEVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDFVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKIVTKEDALLVIL"
     gene            9456..10880
                     /locus_tag="VIB71_000940"
     CDS             9456..10880
                     /locus_tag="VIB71_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8822686.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(10979..11794)
                     /locus_tag="VIB71_000941"
     CDS             complement(10979..11794)
                     /locus_tag="VIB71_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEQ8822687.1"
                     /translation="MIRFLILSGYFELTMYLQLSGKLDQYINVRYSYLAYISMVLSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(11794..12696)
                     /locus_tag="VIB71_000942"
     CDS             complement(11794..12696)
                     /locus_tag="VIB71_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEQ8822688.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            complement(12844..12999)
                     /locus_tag="VIB71_000943"
     CDS             complement(12844..12999)
                     /locus_tag="VIB71_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822689.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDRPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            13233..15365
                     /locus_tag="VIB71_000944"
     CDS             13233..15365
                     /locus_tag="VIB71_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEQ8822690.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYNFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            15352..15789
                     /locus_tag="VIB71_000945"
     CDS             15352..15789
                     /locus_tag="VIB71_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEQ8822691.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            15853..16125
                     /locus_tag="VIB71_000946"
     CDS             15853..16125
                     /locus_tag="VIB71_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEQ8822692.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            16490..17422
                     /locus_tag="VIB71_000947"
     CDS             16490..17422
                     /locus_tag="VIB71_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEQ8822693.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            17419..18198
                     /locus_tag="VIB71_000948"
     CDS             17419..18198
                     /locus_tag="VIB71_000948"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEQ8822694.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            18220..18627
                     /locus_tag="VIB71_000949"
     CDS             18220..18627
                     /locus_tag="VIB71_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEQ8822695.1"
                     /translation="MDLVGISLMIIALGFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            18620..19048
                     /locus_tag="VIB71_000950"
     CDS             18620..19048
                     /locus_tag="VIB71_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ8822696.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH"
     gene            complement(19208..19492)
                     /locus_tag="VIB71_000951"
     CDS             complement(19208..19492)
                     /locus_tag="VIB71_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEQ8822697.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM"
     gene            19691..20617
                     /locus_tag="VIB71_000952"
     CDS             19691..20617
                     /locus_tag="VIB71_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8822698.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            20719..22005
                     /locus_tag="VIB71_000953"
     CDS             20719..22005
                     /locus_tag="VIB71_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ8822699.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            22215..22427
                     /locus_tag="VIB71_000954"
     CDS             22215..22427
                     /locus_tag="VIB71_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEQ8822700.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(22524..22664)
                     /locus_tag="VIB71_000955"
     CDS             complement(22524..22664)
                     /locus_tag="VIB71_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822701.1"
                     /translation="MTKEYISYISATIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(22800..24293)
                     /gene="lysS"
                     /locus_tag="VIB71_000956"
     CDS             complement(22800..24293)
                     /gene="lysS"
                     /locus_tag="VIB71_000956"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEQ8822702.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            24467..25369
                     /locus_tag="VIB71_000957"
     CDS             24467..25369
                     /locus_tag="VIB71_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ8822703.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKHVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDINDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAK"
     gene            complement(25477..26100)
                     /locus_tag="VIB71_000958"
     CDS             complement(25477..26100)
                     /locus_tag="VIB71_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ8822704.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVDFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNTSLTILETKDYLTYDCLIWNDKSFIEV"
     gene            complement(26441..26920)
                     /locus_tag="VIB71_000959"
     CDS             complement(26441..26920)
                     /locus_tag="VIB71_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEQ8822705.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            complement(27011..27574)
                     /gene="thiT"
                     /locus_tag="VIB71_000960"
     CDS             complement(27011..27574)
                     /gene="thiT"
                     /locus_tag="VIB71_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEQ8822706.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMTLSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     regulatory      complement(27619..27715)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(27843..28691)
                     /locus_tag="VIB71_000961"
     CDS             complement(27843..28691)
                     /locus_tag="VIB71_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEQ8822707.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     gene            29016..29519
                     /locus_tag="VIB71_000962"
     CDS             29016..29519
                     /locus_tag="VIB71_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8822708.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFALYPLSQQFPKYQLGCQ
                     AFLVALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            29503..29886
                     /locus_tag="VIB71_000963"
     CDS             29503..29886
                     /locus_tag="VIB71_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEQ8822709.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEILKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     MADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(29932..30411)
                     /locus_tag="VIB71_000964"
     CDS             complement(29932..30411)
                     /locus_tag="VIB71_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEQ8822710.1"
                     /translation="MPNLYDFTVKAQNGNDVSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(30404..32203)
                     /gene="pepF"
                     /locus_tag="VIB71_000965"
     CDS             complement(30404..32203)
                     /gene="pepF"
                     /locus_tag="VIB71_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ8822711.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKTLQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMEDFEVDGKTYKNSFVSYENFYQNHENAEIREKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNELNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVMSTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIINYTEEMSHA"
     gene            32362..35160
                     /gene="ppc"
                     /locus_tag="VIB71_000966"
     CDS             32362..35160
                     /gene="ppc"
                     /locus_tag="VIB71_000966"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEQ8822712.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQAIIAEEVALLKEMLENITRR
                     MIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQNQLTNQPAARMSSSVGLNTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            35299..36603
                     /locus_tag="VIB71_000967"
     CDS             35299..36603
                     /locus_tag="VIB71_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEQ8822713.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSTSGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
BASE COUNT        11311 a         6538 c         7799 g        11117 t
ORIGIN      
        1 ttgatgtata ctgtcattta gaataataat cacatattgt tgtcaacgaa acccaccata
       61 gtctataatg aaagcctagt agggatgagc tatataccaa ctatctatca atccagacgt
      121 ctctactaaa aaatactccg tcttctatga aactagaaac ggagtatttc tgtttgtcta
      181 taccactaaa tgaacagtta tatagaaagg tgattggatg tttggaataa acatcatgaa
      241 aaaaatttga gaccttctta tatcctaaac tagaacgaat gtctagtgaa ataaaaaaaa
      301 acgacaccat taggatgtat tttggactaa tgtcaaataa gtagacagaa aaccgtgtta
      361 ttttattacg ttaaactaat tttcttcttt ctgattaggg gttagtccta gattagccgt
      421 atgtgggttg taattgttat aaaaattctc aatgtattca aagcagtcta attgaacctg
      481 tttgatattt tgatactttt ttcggttgat ttgtctatgc tttaaatact tgaaaaatgc
      541 ttcagttacg gcattatcat aaggatatcc aggtttagaa aaagaatgca tgatagtgtt
      601 gtcatcaatt atttttctca atttcctggc cttaaattgt gacccttggt cggaatgaaa
      661 gagaagtgtt ccttcaatct ttcttttatt aagagctaat tctagagtgt cacatgctaa
      721 ctttgcatcc atatgatgac tcagtttcca agcaatacat tttctagaat agagatcaag
      781 tattgcgcag agatagacat atttcttata tccaatagaa atataggtga agtcagtaga
      841 ccatacttga tttggtttgt caggattaaa tttctggttg agtaagtttt gaggatacgt
      901 tttttgagtc cttttaagag ctgtttttgg cttaacggta gccattttag ggagcgccat
      961 attcttcata agacggtaaa ttcttccttc agagattttt gtgtcgtagt ctctttgaag
     1021 aatgaccttg atagacttca caccaagtct tttgtttgct ttggtataaa tctcaagtat
     1081 ttgttttcta taaatttgat tatccaattc tcttttggag ggcttatgtt ttagaaattt
     1141 atagtaagtg gagcgattga cacgtaaaac acgacataag gttgttgtgg cgtgttcaaa
     1201 gcgtaaccga tagacagcga ggagtcttac tttaagtttt gcatgaatat ggcacttgct
     1261 ttttttagga taaggttctc ctcttcaagc tgcgcattac gtttttgtag ctcttgtatt
     1321 tgcttggcag taagtacaga attatcttcg agtttgactt gagaatactg tttgatccat
     1381 tttgcaagcg cagaagcgga taccccatag tctttacaga gttcagactg agtttttcca
     1441 gtttgataaa ggttgacaag agattgtttg aattcttcat cgtagcgttt aactgttgac
     1501 ataggttgtc ctttcgtttt tgtgtctttt aaaacagatt gtaacacaca aagttttgtc
     1561 tacttttata gtatacatcc agtggtcatt tataaaaata aaaaagtagc agttcacttc
     1621 aaaaacggtc aggttatcga aatataatct ggctgttttt tacgaatgga atgaaagctg
     1681 ctttttatga tataataaga aaaattgaac agaatgcaga aatgatgggg cttatttaaa
     1741 tcgttaaaaa gtgcacaccc taaatggcgt ttgcaccccc ctagagtaaa aaaaggagac
     1801 attgtatgat taaactaata gcaacagata tggatggtac cttcctagct gaagatggta
     1861 cttataatca agagcaacta gctgcgctct tgccaaagtt agccgaaaaa ggcattttat
     1921 ttgcggtttc gagtggccgc tcgctcttag ccattgatca gctctttgag ccctttttgg
     1981 atcagattgc tgttattgca gaaaatggtt ccgtggttca ataccatggt gagattctat
     2041 ttgcagatat gatgaccaaa gagcagtata ccgaagttgc aaaaaaggtt ttagccaatc
     2101 ctcactatgt agaaacaggt atggtttttt ctgggcaaaa ggcagcctat attttaaaag
     2161 gcgcatcaga agagtacatt caaaaaacaa aacattacta tgctaatgtt aaggttatta
     2221 atggttttga agatatggag aatgacgcca tttttaaagt ttctaccaac ttcacaggcc
     2281 ataccgtctt agaaggaagc gattggttga atcaagccct cccttatgcc actgcagtga
     2341 ccaccggctt tgattccatt gatattatct taaaagaggt gaataagggc tttggtatgg
     2401 agcatctttg tcaagccttg ggcattaaga aagcagaaac gattgctttt ggggataatt
     2461 ttaatgatta ccagatgttg gagtttgctg gtagggctat tgctacggaa aatgcaagac
     2521 ctgaaatcaa agtgatttca gaccaagtca ttggccactg taatgacgga gcagtactaa
     2581 cgtatttaaa aggactagtg taactcatga atattagaat tttggcgctt gatttagacg
     2641 gtaccctcta caacactgaa aaaattgtca cagatgccaa taaaaaagcc ttagcagcgg
     2701 ctagagaaaa aggggttaag gtggttatta ccacaggtcg ccctctaaag gccatcggta
     2761 acttgctaga agagttggac ttgcttgacc acgatgacta cagtattacc tttaatgggg
     2821 gtttggttca gcgaaataca ggggaggttt tggataagag ctctctcagt tttgaccagg
     2881 tttgccagat tcagcaagct ttagaggcgg ttggcttacc aacagatatt atcagtggtg
     2941 gggatgtgta tagcattcca agtaaggacg gtaggcattc gcagtaccat ctagctaacc
     3001 cactgttgac ctttattgag gtgacatctg tagcggaact accaaaagac attacctata
     3061 acaaaattgt gacagtcacc gatccagact ttttggatca gcagattata aagctatccc
     3121 caagcttatt tgaggatttt gaagccttta aatcacgaga tattattttt gaaatcatgc
     3181 caaaaggcat tgataaagct tttggattaa acttgctttg tcagcacctt ggccttgacg
     3241 ctagacatgt catggctatg ggagacgaag ctaacgactt tgcgatgtta gaatgggcag
     3301 gacttggagt agctatggct aatggtgttt caggagctaa agccgttgcc gatgccgtga
     3361 ccaccttgac caatgatgag tctggggttg cagaagctgt gaagacattt attttagaag
     3421 aggagagtta atgggattat ttgatcgttt atttgggaaa aaagaaaccc cgaaggtagc
     3481 tgaggaaaag ttagaagaaa atcttttgac agaaacaact cagaaagagg agctttctga
     3541 aaaagccaat gagcaagaca agattgaggt ggttcaacaa gaggacgttt cttcagaggg
     3601 cgcaggttcg gtggaaaatg gtcccgaagc agcttcagta aatgcacagg ttgaggaaga
     3661 aacaggtgat aatagtaatc attcatcaga agataccaat gagtttgctg ccgacaaaac
     3721 agaccttaag gtaagtgaac ttagtcaatc tacggcatca gaaccaaaag accttgttga
     3781 ccagccagtt gtggaacagt ttccaacaaa acaagcccaa gctgatgcct caaatgattc
     3841 ggcgaatgaa gaagcagtag acacttcaaa agagcaatcc agtagccaac aggttatgga
     3901 agactactac cgtcgtaagg ctgctcttga aaaaagcctt caagaaaaag cagcggcaac
     3961 ggttccagtg atgccagaag aagttccaca agaaaatcaa gcctctacct cagcagaagc
     4021 ttctcaaaac aaggcaacct acgataccat tcctgagaca gatcaagaaa aatacaagcg
     4081 tagcttgaaa aaaacgcgga ctggcttctc agctcgtctg aacagtttct ttgccaattt
     4141 caggcgagtg gatgaagaat tctttgaaga cttggaagaa atgctgatct tatcagatgt
     4201 cggtgtacat gtggcgacaa ctttgacaga ggagttgcgt tatgaagcca aactggaaaa
     4261 tgcgaaaaaa ccagatgcct tgaaacgtgt gattgtggaa aaattggtag atatctatga
     4321 aaaagacggg cgttataatg aagccattaa ttatcaagat ggcttgacgg ttatgctttt
     4381 tgtaggtgtt aacggggttg gtaaaacgac ttcaatcggg aagctggctt accgttacaa
     4441 acaagaaggt aaaaaagtca tgttggtggc agcagatacc ttccgagcag gggctgtggc
     4501 tcagctagtc gaatggggac gccgagtaga tgtgccagtc attactggcc ctgaaaaggc
     4561 tgatccagcg tctgttgttt ttgacgggat ggaaaaagct gtggcaaaag aagtagatat
     4621 tcttctgatt gatacggctg gtcgcctgca gaacaaagaa aatctcatgg cagagctgga
     4681 aaaaatgggt cgtatcatta agcgcgttct accagatgcc cctcatgaaa cgcttttggc
     4741 cttagatgcg tcaacaggtc aaaatgcgct tagccaagcc aaggaatttt caaaaataac
     4801 acctttaaca ggcttaattt taacgaaaat tgatgggact gcaaaaggtg gggtggtcct
     4861 agccatccgt caagaattag acattccagt caagttcatc ggatttggtg aaaaagtgga
     4921 tgatattgga gaattccact cagaagactt tatgaaaggt cttttagaag gtattttata
     4981 agaaaaaaaa ccagtcttgt tcaacagaac gaggctggtt tttaagtaag tcagcttagg
     5041 caagtccttt tttccctaaa tggtaaaaca tagcaaagaa aaagataaaa tcaagtagag
     5101 caaaaatagt aaagagaagg tagacagact ggacaccgct tgtgaattct ggttgactat
     5161 ttgctatcag tgatgccata gcagttccta gagcgccagc aaattgctgc atcatctgaa
     5221 aaatggccgt ggcatcggca tttttctcgg caggcaattc tcgaatagcc gtggctaagc
     5281 tattattaaa gcccatgtta cgcccaaacg tgaataaaat atataaaaga gtgaatggta
     5341 aaagcataaa atgtcttgtt tgaagtgtca taataatcaa tgataaacta aataaggcat
     5401 ttcctaaata aagcgaaagt cttgctcctt tttgatcata aagtttacca aaagcaggtg
     5461 ctagtagagc tccgagtaag gtaccaggta gtaataccat accagcttga gaactattcg
     5521 caatcttttc catgacaata aagtttggcg ttagaaaatt tatgcctaaa ttaatcagct
     5581 ggaagacaaa aaagggaatc aggccaaagg ttagagaggg aattttgaga atgcgaatat
     5641 caagaaaggg ttgcttagct gtgagattct tgtagaggaa gaggataagg ctgagaataa
     5701 aaagccctaa gtaatacaaa ttaacacttc cgttttctag actagtaata gccaataagg
     5761 cagaagttaa gctaatcgat agtgcaataa atgccaacca gtcaaagggt actttttcgc
     5821 ttactggaga atcttcgagg tagtaataag ctagaatacc tgcaatcagt ggtacaggga
     5881 gtatacagat aaaaatccat tgccaattaa aatggctaat cataaagccc ccataagtag
     5941 gcccaaaagc aggtgctaag ctaataataa gaccagcaaa tcccataaat agacctacct
     6001 tatgcattgg gacacgctct aaaataatat taaacatctg aggcattacc agaccagtac
     6061 caatgccttg aaaaatgcgg gctagcaaca tgatcgcaaa ggactgggtc agaacggcca
     6121 agatggtgcc aaatgtaaaa agacctgtgg ccataaaaaa gaggggtctt tcccgcacat
     6181 tttttttcag tgtagccgaa gtggtcatca taatcgccac tgctagtaaa taaatggtcg
     6241 tcatccattg caagctattt aagggcaact gatagactga catcagtgtc gggaaggtga
     6301 cattcatact ggtttcagac aaaattcctg aaaaaccaat gagtgctatg gcgataatcg
     6361 ccataattgt ttgttttgaa acggtttgtt gatgatgtga catgataact cctttatcta
     6421 atcgattgtt attgtatcat ataatcttaa aattgtcaga aactcttttt tgctaaatca
     6481 atagatacga ataacaatag ttgctctttc agagaatttt ttgaaaacgc ttgacagaat
     6541 cttaaagaga tgataacatt aaagcgttct cagatgtgat tacttcaagt aagcaggcta
     6601 gagacataac aatcagaata ttaaaggatg ttatcacagt tttgtgagca gggacctatt
     6661 cgaaaagtgc tttttagcga gcttttggat aggtcatttt ttattgtgat actaaaggac
     6721 taggactttt atgttgatta aacgcgtttt aaaccataat gcggcgattt cgaccaacca
     6781 tcaaggatta gatattttat tgatgggaaa agggattgcc tttggaaaaa aagttggaga
     6841 tagtattgag cttaatgcta tcgaaacatc atttgtttta aaaaatagtg acaatatgaa
     6901 tcgcttcaca gagttattta ttacggtgcc acaagaagtt gttgcttgct cagagagaat
     6961 tatcaatcta ggtaaaatta aattaggcaa aaccttagat gaaattctct atattaattt
     7021 aacggatcat attcactctg ctattgaaag gcatgagcaa ggaatgttga ttcataaccc
     7081 actacggtgg gagattcaac gctattatcc tgatgaatat agtctagggg taaaagcctt
     7141 agagctaatt gagcgtaatc taggagtcac tctagctatt gatgaagcag cttttattgc
     7201 catgcatttt gtcaatgcta gtttggacac tccttttaag gagccacatc gcctgacgga
     7261 gattgtttct tatattgagc aaaaaatcaa aacagacttc aaaacagaat tggatgacac
     7321 atccatcgat tattaccgct ttatgaccca tattaaatta tttgctcaac gtgtgttatc
     7381 agagatgtct tacgatgatg atgatgcaga actgcttata gtggtgaaaa cgaaataccc
     7441 taaagaatat cggtgcgtct tagatattag tgaggagata aaaaagcggt acaactatca
     7501 ccttaattca agcgaacttt tgtatttgac ggttcatgtt aaacgtttag tgaaacattt
     7561 aaaggagact taatatgacg tatcaagaaa ctgccaaggc tattttagcg gcggttggtg
     7621 gcaaaacaaa tattcaacgt gtgacacact gtgtaacacg tctacgctta gtactgaaaa
     7681 atgatgagaa agttaaagat cagcaagtca aatccatttc aaatgtgatt ggcgtgatgc
     7741 gcaaaaacgg ccagtaccaa attatcttgg gcaatgatgt caataattat taccaagcct
     7801 ttttaagcct agggcatttt gacaatcaag atgaagatca ttcttcaaaa gcgaaaggaa
     7861 gtatccttga gcgcttgatt gaaaccattg ctggtgtgat tacaccgctg attccagccc
     7921 ttcttggtgg tggaatgctc aaagtggtgg ggatcttgct tcctatgctt ggcttagcga
     7981 gtgcggactc tcaaaccgtt gcctttatta acttctttgg cgatgcggct tattatttta
     8041 tgcctgtcat gattgcctat tcagcagcgg cgcgctttaa ggtgacacct gttttagcag
     8101 cgacgatcgc agggatttta ttgcatcctg cctttgttgc aatggtagca gaaggtaaac
     8161 cattggcttt atttggagca ccagtcactc ctgctagcta tggctcatct gttattccca
     8221 ttttgatgat ggtttacttg atgcaataca ttgaaaaatg ggtcaatcgc ttggtgccaa
     8281 gcgtgatgaa aagcttctta cagccaacct taatcatttt gatttctggc tttttggctt
     8341 tagtggttgt aggtcctctt ggtgtgatta ttggtcaagg gttatctaat accatgctcg
     8401 ctatttatca tgtggctccg tggctagcac ttgccatttt gggagcgatt atgccgcttg
     8461 ttgtcatgac ggggatgcac tgggcttttg caccaatctt tttggccgct tcggtcgcaa
     8521 caccagatgt cttgatttta ccagcaatgt tggcttctaa tttggctcaa ggagccgcat
     8581 ctttggctgt tgcctttaaa acaaagcaga aacaaacacg tcaagttgcc cttgccgcgg
     8641 ggatttcagc tttgctggca ggtatcacgg aaccggcact ttatggggtc acactgaaat
     8701 ttaaaaagcc actctatgca gccatgattt caggtggtct ggttggagcc tttattggtt
     8761 ttgtcaatat tgcttcttat acctttgtcg taccttctat tattggttta ccacagtaca
     8821 tcaacccatc aggcggagct aattttacaa atgctttgat tgccggagct gcgacgattg
     8881 tgttagcctt cagtttgact tggttcatgg gaattgatga agaatcccca gagcaagtga
     8941 gtgttgcagc agatatgtca caagttaaga gcggcttgtc aaccaaacaa acgttgtatg
     9001 ctccaatgac aggtgagatg ctttttctat cagaagttcc tgatgaaacc ttttcttcca
     9061 agttattagg agaaggattt gccatattac caagcgaagg tgaggtctat gccccctttg
     9121 atggtgaagt catcactttc tttccaacca agcatgctgt tgccttaaaa aacacacgtg
     9181 gtgtggaagt cttgattcat gtcggtattg atacggttga gttaaaaggg caaggtttcg
     9241 agcagttagt gtctgttggc gatttcgtga aacgaggcca ggcacttcta aaaatggata
     9301 ttgatttcat tacttcaaaa ggctattcac tcatcagtcc tgtggtcgtg accaattcgg
     9361 ctgagcagtt ggagattatt attcaagatg acaaaaaaat agtgactaaa gaggacgctt
     9421 tgttagtcat tttataacct aaaaggagag ggagaatggg aatttttcca aaagatttct
     9481 tatggggcgg cgcagtagct gccaaccaag tggaaggagc atttgaggca gacgcaaaag
     9541 gtttgtccgt acaagatgtt ctaccaaatg gtggactagg agaatggaca gatagtccta
     9601 ccagcgataa tttaacttta gaggcgattg atttttacca ccgctacaaa gaagacattg
     9661 ctctttttgc cgagatgggc tttaaagtct ttcgaacgtc tattgcttgg tctcgtattt
     9721 ttccaaatgg tgacgatgac cagcccaatg aagcaggttt gcaattttat gatgacttat
     9781 tcgatgaatt gttgaactat ggtatcgaac ccttagtgac cttgtcgcat tatgagacac
     9841 ctctgcattt ggccaaagcc tataatggtt ggacagatag acgtctgatt ggcttttttg
     9901 agcgctttgc tcagacagtc atggaacgct ataaggacaa agtcaaatac tggttgacct
     9961 tcaacgaagt caactcgatt ttacacatgc cctttaccag tggtggcatc atgacagaaa
    10021 aagaaaagct gagcctgcaa gatttatacc aagctattca tcatgaattg gtagcatctg
    10081 ctagtgtcac aaagctagcg catgaaatca atcctgatgt taaagttggg tgtatgattt
    10141 tggcgatgcc tgcttaccca atgacctctg atcctcgtga tatacttgct gcgcatgcat
    10201 ttgaaaatct taatctctta ttttcagata ttcatgtgag aggcaagtat ccttcatata
    10261 ttaagtcgta ttttaaagaa aatgggattg agattgtttt tgaagacgga gacaaggaat
    10321 tattagcgga acatacggtt gattttctat cctttagcta ttacatgagt gtcacacaag
    10381 cccacaatcc tgaagcttac acatctggtc agggaaatat tctaggtggt ttgtccaatc
    10441 catatttaga atcttcggag tggggttggc agatagaccc aattggtctg cgattggtct
    10501 tgaatcagta ctatgaccgc taccagattc ctttgtttat tgttgaaaat ggcttaggtg
    10561 caaaggatca gctggtgcaa accgcagatg gcagcatgac ggttcacgat gattatcgca
    10621 ttgactacat gagtcagcat ctcgtacaag ttgccaaagc gattgaagat ggcgttgagg
    10681 tcatgggtta cactgcttgg ggctgtattg attgtgtctc tatgtcaaca gcccaattaa
    10741 gtaagcgcta cggttttatt tatgttgacc gaaatgatga tggtactggt caactcacac
    10801 gctataagaa aaaatcattt gattggtacc gacaagtcat tcaaaccaat ggacgttacc
    10861 ttgaggataa tttttcctaa ataggtcttg tttaagatgg tgactctgtt cctatgctaa
    10921 ctgataaaac gcaaaaagca tttgttttga taaaaaacaa gtgctttttt attagtcttt
    10981 aaaaaacgcg gtaaacataa ggattattag gttctttggt ttgatgaacc tcagcaagtt
    11041 gaaggacagg tagatgttgt tctaagtttt tatcatattc catatgaagg cgacctttaa
    11101 ctgttagcca tgtattgtta gggtagctgg tttgattacc tgtggtcaaa agtccgtaca
    11161 ctcctgagtc ggcaatacag tgaataatgc cgaagcggaa aaggaattgg tagttgtcat
    11221 ggcccggttc gttataaaca aagccagtgt attggatgtc acgatcaaga aactcatctg
    11281 ggtagagata gatcaattcc atcacttcca tataattttc agtggtaatg gtgaccggtt
    11341 tcttgccttt atatttatgg agttcttgac gcatctcctt ttggtaggca gactttgtaa
    11401 agtaaaggct ggtatcaggt ttgaggtatt gaatggtggt accgtcatca ctgactcccg
    11461 ttttagaggc tcccgcagcc aatgggaaag tatagccttt agcagaaacc gtggtggaat
    11521 ctagggttac tgttggcaca aggagaccaa tcaaaacagg aaagaccaag ataaaaggac
    11581 tggtcagcct tgcgattttt cctgttaaat ggctatgtac cttaatgttt ttcatccagg
    11641 tatagagttg aacaagagct aaaatgaaag ataaaaccat ggaaatataa gcaaggtaag
    11701 aataccgaac attgatgtac tgatccagtt tgccagacag ctggagatac atggttagtt
    11761 caaaatagcc agataaaatt aaaaagcgaa tcattagagc acccccacaa gtaaacaata
    11821 aacggcaatc ataagaacgg atacgccgat aaattggaca atgaagcgtc ctttaaaagc
    11881 ctttaccatc atcataaggt ttttaatatc caccatagga ccaattaaaa gaaaggcaag
    11941 aactggagcc actccaaagg tggataataa ggaagctccg ataaaggcat cggcttcact
    12001 acataatgat agaatgaaag ccatcagcat catgatcaaa atggctgtca agggattgtg
    12061 cccaatcgtt gtcaacacac gagttgggac atatatttgc atggcagagg caatcaaggt
    12121 tccaaatacg agatacctac cggtgtcgaa gaattcatca atagcatgta ccagtgctag
    12181 ataaatgcgt tttggcaagc tttcatgaga ataatcatga aaatgcacgg gttgagcatt
    12241 atccttgaga atgttatcat ctacaataaa agctaacatt accccaagtg taatggctac
    12301 tagtgcagca ccgaccaagc gaagtatcag aaagcgcaaa gaattcccaa aagcagaata
    12361 agtagcgaac aaaacaatag gattaataat aggcgctgtt gccagaaaag ggacggccgt
    12421 ataactaggc accttttttt ccaaaaagcg gttgatgatg ggaataatcc cgcattcaca
    12481 agaaggaaaa acaaatccaa caaaggttcc aaacagaatg cgcaagcatt tttgcttagg
    12541 taggtatttt tgaaccaatt ctggcgttac aaagacttca atacaaccag ataaaatagt
    12601 tcctaggagc acaaaaggaa gagcttcaat gataatggac ataaaaatcg caaaccattg
    12661 caagacactg ggaggaaggt tggaaaagag tgacattcac catatccttt ctagatgata
    12721 aaagaggagg ctgaaacacg aatgttcagc ctcgactgat acgttttgtt agcctgatcg
    12781 ctaaaaatct ctcaactcag tttaaacgaa tggacgatat gttaagagaa tgagacaaac
    12841 tagctatggt ttgcttggtt ttgtttgttc tgtcgttttt tctttggtcg ctagtttacc
    12901 atcagtattg acttccaaag gcctatcaaa actagggatt gatgcaaagc ctgctagcat
    12961 tttttcaagt tcatcatttt ttttatgggt aattgccata tctatgacct tctttcattc
    13021 aagataagtc tattatacta tcatttgaga acaatgccaa aacggaagtg ttgtttactt
    13081 ctttcttttt taaaattagg tattgttatt tagggtttcg tcagttattt actaaaagta
    13141 gctttttttg attctttacg caactttata ttaggacaat gtttcgctat cattttttgc
    13201 attaatatgg tttgtgttat aatagcaata ttatggaaaa taacaataat cacaacattg
    13261 cagaggcttt gtcagttagt ctccatcaaa ttgaacaggt gcttgcccta acagcacaag
    13321 gcaataccat tccctttatt gcacgttacc gtaaagaagt aacaggaaat ctagatgaag
    13381 tggtgattaa gtccattatt gatatggata agtctctcac taccctgaat gagcgcaaag
    13441 caaccattct cgctaaaatt gaggaacagg gaaaactgac agatcagtta cgaacgagta
    13501 ttgaagcaac cgaaaaactc gctgatttgg aagagttgta cctgccttat aaggaaaaac
    13561 gccgtacaaa agcgacgatt gcgcgtgaag caggcttgtt cccattagcg cgtttgattt
    13621 tacaaaatgc gcaaaacctt gaaacagcag cagaaccctt tgtcacagaa ggatttgcca
    13681 gcccacaaga agctctagca ggagctgtgg acatccttgt ggaggccatg tcagaagatg
    13741 ctaaactacg ctcttggacc tacaatgaga tttggcagta cagccgctta gtatcaacgc
    13801 ttaaagatga gcagttggat gagaaaaagg ttttccaaat ctattacaat ttttctgacc
    13861 aagtgtctaa catgcaagga tatcgtactt tagcccttaa ccgtggcgaa aagttaggca
    13921 tcttaaaagt gtcttttgag cataacttgg agaaaatgca acgctttttc agtgtgcggt
    13981 tcaaagaaac caacccttat attgaagagg tcatcaatca gaccatcaaa aagaaaattg
    14041 ttccagctat ggaaagacgg gttcgttcag aactcagtga tgccgcagaa gatggggcta
    14101 tccacctctt ttctgaaaat ctccgtcatc ttttgttagt gtctccttta aaagggaaaa
    14161 tggttcttgg gtttgaccct gcctttcgaa caggtgcaaa attggctatc gttgatcaga
    14221 ctggaaaatt gttgactact caggttattt atcccgtagc accagctagc caaacgaaga
    14281 ttcaagcagc taaagaaaca ctgactcagc tcattgagac ttaccagatt gatattattg
    14341 ccattggaaa cggaacagcc agtcgggaaa gtgaagcctt tgtagcagac gttttgaaag
    14401 atttcccaaa tacgtcctat gtcatcgtta acgaaagcgg tgcttctgtt tattcagcgt
    14461 cagagttagc ccgccatgag tttccagacc tcacagtgga gaagcgctct gctatttcta
    14521 ttgctcgtcg cttgcaagac ccactcgcag aattggttaa aattgatcct aaatctattg
    14581 gcgtcggtca gtaccagcac gatgtgagtc agaaaaagtt gagtgagaat cttggttttg
    14641 ttgtggatac tgtggttaac caagttggtg ttaatgtgaa cacggctagt ccatctttat
    14701 tagcacatgt gtcaggtttg aacaaaacga tttcagaaaa tattgtcaaa taccgcgaag
    14761 aaaatggagc actgacatca cgcgctgaca tcaaaaaagt gccgcgttta ggagctaagg
    14821 cgtttgagca agcagcaggt tttctcagaa ttccaggagc caaaaatatt ttagacaaca
    14881 caggagttca ccccgagtcc tacccagcag tcaaagaact ctttaaggta cttggtattc
    14941 aggacttgga cgacgctgcc aaggcaactt tagcagcagt tcaagttccc caaatggcag
    15001 aaacattggc tattgggcag gaaaccctta aagatatcat tgctgatctc cttaaaccag
    15061 gtcgtgacct tcgtgatgac tttgaagcac caatcttacg tcaagatatc cttgatttga
    15121 aagatttgga aattggccag aagcttgaag gaactgtgag aaacgtcgtt gactttggtg
    15181 cttttgtaga cattggtgtt catgaagatg ggcttattca catttctgaa atgagcaaaa
    15241 cctttgtcaa ccaccctagt caagttgttt cagtgggtga cttggtaact gtttgggtct
    15301 ctaagattga cttggaccgc cacaaggtca atctcagcct attgccaccg cgtgacactc
    15361 actaattatg tccaagaagt ttccctggct gattttggca aaccatttca ccacaaggct
    15421 tattggaaca agcgcctaaa aacaactggc ggtcgctttt ttccaaaaga tggtcatttg
    15481 gattttaacc ctaggatgct tgaggagcac ggtgagctta tttttcggaa aattgttcgc
    15541 catgagctct gccattacca tctttatttt gaaggaagag ggtaccatca taaagatagg
    15601 gatttcaaag atctgctagc tcaagtaaac gggcttcgtt atgtcccaac tagctctaaa
    15661 tcaaagacta atcatcatta tagttgccaa acctgtgggc aggtttatca acgaaaaagg
    15721 cgtatcaatc tggctaaata tgtttgtgga aattgccacg ggaaacttat ggaaaaaaat
    15781 cagtcgtaag actggtttta ttttgcgaaa aacaatgtaa actagtatca tagaatgagg
    15841 aggtaaagaa acgtggaaac taaattctat aaacagcgaa aaaatcgctt ggttgcaggt
    15901 gtcattgctg gtttagcaga taagtatggt tgggatcttg ctctagcgcg tgtcttagcg
    15961 gctcttctta tttacggaac tggttttgga gttttgcttt atattttgtt ggccatcttc
    16021 ttaccttaca aggaagactt gcttgaagaa cgttatggcc gaggtcctcg tcgtcgtaaa
    16081 gacgctgatg tcttaaatga agaagaagat ggctggttct ggtaaacaat cagttaaaat
    16141 gataattcat cacgtaagag caaccatgtg attaactgat gataataaaa tgttttgata
    16201 tgtaagtaag cgaggggtct tatcagctat gatgaggctt tttgcttttt gacttagtaa
    16261 gatgatacct ttttaaatac cataataagc actaattgct caatgatact agtaaagtat
    16321 ttgtttgcca ttgtcttatt tttgactcat atctctaaat gataaaacct agtttttaat
    16381 agagctaaga ccatttttgg tgtcgttgtt ctcatttagt agtgaaaaaa tgagtatttg
    16441 caagggtcta acggtcgatt tgtgttataa tattgaaaaa ggagaaatta tgaccgttac
    16501 tgtaaagatg ctagtgcaaa aagttaaact tgatgtggtt tatgctacag ataacttgct
    16561 gtcaaaagag ataacaacat cagatatttc acgtccaggt cttgaaatga ctggttattt
    16621 tgattattat gctccagaaa ggttgcagct gtttggaatg aaagagtggt cttatcttac
    16681 acagatgact tctcacaacc gttattctgt tttaaaagag atgttcaaaa aggacactcc
    16741 tgcagtggtt gtctctagaa atttagccat tccaaaagaa atggttcaag ctgcaaaaga
    16801 agaaggtatt tcacttttaa gtagccgtgt ttcaactagc cgcttagctg gagaaatgtc
    16861 ttattttctt gacgcttctt tagctgaacg tactagtgtt cacggcgttt taatggatat
    16921 ttatggtatg ggggttctta tccaagggga ttctggaatt ggtaaaagtg agactggttt
    16981 agaattagtt aagcgagggc atcgtttggt tgcagatgac cgtgtggatg tctatgccaa
    17041 agatgaagaa accctttggg gagagccagc agagatcttg cgccacttgc ttgaaattcg
    17101 tggggtaggt attattgatg tgatgtcgct ttatggagct agtgctgtga aggactcatc
    17161 acaagttcaa ttggccattt accttgaaaa ctttgaggct ggtaaagttt ttgatcgtct
    17221 cggaaacggt aatgaggaga taactttctc aggagtgaga atccctcgta ttcgtattcc
    17281 ggtaaaaaca ggtcgaaatg tttcagtggt tattgaagcc gctgcgatga atcatcgggc
    17341 taaagaaatg ggctttgatg ctacaaaaac ttttgaagat cgtttaactc aactaatcac
    17401 caaaaatgag gtgagtcaat gatcaatccc attgccttaa aatgtggtcc actagccatc
    17461 cactggtatg ctctatgtat cttgtcagga cttgttttgg cggtttactt agcatcaaaa
    17521 gaagcaccca aaaaaggaat atcatctgac gctattttcg attttattct gattgctttt
    17581 ccacttgcta ttgttggtgc aagaatttac tatgttattt ttgaatggtc ttattatgtc
    17641 aagcatttag atgaaatcat agccatttgg aatggcggta ttgctattta tggcggtctc
    17701 attacaggag ctcttgtact tttggcttac tgttataaca aggtgctcaa tcccattcat
    17761 tttttagata ttgccgcacc aagtgtcatg gtcgctcaag ctatcggtcg ctggggaaat
    17821 tttatcaacc aagaagccta tggtaaagct gtgagccagt taaattactt accaagcttt
    17881 attcaaaagc aaatgtttat agagggaagt taccgcattc cgacctttct ctatgaatca
    17941 ctttggaatc ttttgggatt tgtcattatt atgatgtggc gtcgtaagcc aaaaagtcta
    18001 ttagatggag aaatctttgc attttactta atttggtatg gtagtggaag actagtcatt
    18061 gaaggtatgc gaacagatag tcttatgttt ttaggtattc gcatctccca atatgtgtct
    18121 gccttattaa ttattattgg cttaatcttt gttataaaaa gacgtcgtca aaaaggaatt
    18181 tcttattatc aagaataagg atagaaaaag gagaaactta tggacttagt tggaatctca
    18241 ctgatgatta ttgcactcgg atttgttgct ttggtgattt tcttgattat tgtattaaag
    18301 aaagtctcag aaacaattga tgaagccaaa aaaacgattt ctgtattgac aagtgatgtt
    18361 aatgtgacac ttcatcaaac taatgatatt ttagcaaaag ctaatatcct tgttgaagat
    18421 gttaatggta aagtagcaac catcgatcca ctgtttgttg ctattgctga tttgtcagaa
    18481 agtctttcag atttaaatag tcaagcaagg cattttgggc aaaaagcaac taatgctaca
    18541 ggtaatgttt caaaagctgg aaaattagca ttagttggta aagtagcctc aaaagtattt
    18601 ggaaaaaaag gagaaaagca tgaataaaag tttcaaaaac ttagtgattg gagctgtttc
    18661 aggagtagcg gcagcttact ttttatcaac agaaaaaggc aaggctttga aaaatcgtgc
    18721 tgaaaaagct tatcaagcct acaaagaaag tccagatgat taccaccaat ttgctaaaga
    18781 aaaaggtagt gaatacagcc atttagcacg tgatactttc tatgatgtga aagataagtt
    18841 ggcttctggt gacttaacta aagaggacat gttagacttg ctcaaagata aaacaacagc
    18901 tttcgtgcaa aaaacaaaag aaacccttgc cgaagttgaa gcgaaagaaa agcaagatga
    18961 tgttatcatt gatttaaatg aagaagacat catcattgac tatactgaac aagatgagcc
    19021 tgttagtgat acactagata aacactaact aaaacgacct aaaacataga agaagaaaag
    19081 attgaaggat ctgatcacta gtcccgatgg ttagttttag gctaactgaa gaaggggggt
    19141 attgtggctt caatcttttt ttgtttttga cacaaaaaaa agagtcacgt aaaacggact
    19201 ctggaagtta catcagtaat gatttgataa ccttggctaa taaggaagta atgcctaagc
    19261 tgatgatgct tgcaaataag aaagcaaaca ttggcgctaa attcattacg agcaggacaa
    19321 atgcaaataa aacggtaata aggctgaaac tagcgatacg agcaaagaag actaattctt
    19381 ttagctttgc actttggcca ttgaactctt gaaaatctcg aaatttactt tgagattctt
    19441 ggtaagaatc atcctgttca accgaattat gcttctttaa cggtgcaggc atagtcctct
    19501 cctttcctta acatactaag taattctatc ataaaagtct cttcttgtca tcttttttta
    19561 aaagatttga aaagatttac taatgacaag tgacttatca tgctataaca gtaaggggac
    19621 tagcttaacg tttgggcttt tgcaagaaat atgcttaagg tcttaaaatt tttggtataa
    19681 taaagcttat atggaaaaaa taattattac agccacagct gaaagcattg agcaagtcaa
    19741 agctttatta gctgctggtg ttgatcgtat ttatgttggt gaagccaatt acgggttacg
    19801 tcttccccat aacttttctt atgatgaatt gagacaaatt gccaaactag tgcatgatgc
    19861 aggcaaagag ttgacagtag cttgcaatgc tttgatgcat caagatatga tggatcagat
    19921 caaacccttt ttagacttaa tgatagagat tgctgttgat tatcttgtgg ttggtgatgc
    19981 aggtgtgttt tatgtcaata aaagggatgg ctataacttt aaactgattt atgatacctc
    20041 tgtttttgtg acttctagcc gtcaggtaaa tttctggggg caacatggtg ctgttgaaag
    20101 tgttttagca agggaaatcc catcagcaga gttattcacc ttagctgaaa atttggaatt
    20161 tccagcagag gtgctagttt acggcgcctc ggtgattcat cactcgaaac gtcccttgct
    20221 agaaaattat taccatttta caaagattga tgatgaggtt agtcgtgaac gaggactttt
    20281 cttggcagaa ccaggagatg ctagcagcca ttactccatt tatgaagaca atcatggcac
    20341 tcatattttc attaataacg atatcgacat gatgtctaaa ttgggtgagc tgtatgcgca
    20401 tggcttaact cattggaagc tagatggcat ttactgtcca ggtgatgatt ttgtcgctat
    20461 tactaaattg tttattcagg ctaaaacctt attagaagct gggcaattta cccaagaaga
    20521 agctgaaaag cttgatcaag cagtgcatgc ccatcatcca gctggccgtg gattagatac
    20581 tggcttttat gagttcgatc caaaaaccgt taaataagta atccttgtct tgagtgagtt
    20641 tactatttca gggcaagaca gggttatgac accattacac aggtaatcta cctatcttga
    20701 aaatagaaag aatatcacat gtcacatatg aaaaaacgtc ccgaggtctt atcacctgct
    20761 ggaacacttg aaaaattaaa agttgcgatt gactatggcg cagatgctgt ttttgttgga
    20821 gggcaggcct atggcctaag aagccgcgct ggtaacttct ctatggaaga attgcaagaa
    20881 ggcattgatt atgcacatgc gcgtggagct aaggtctatg ttgctgctaa catggttacc
    20941 cacgaaggga acgaaattgg tgcgggcgag tggtttcgtc aactgcgtga tatggggctt
    21001 gatgcggtca ttgtttcaga tccagccttg attgttattt gttcaacaga agccccaggt
    21061 ttggaaattc atttgtcaac gcaagcttca tctaccaatt acgagacctt tgaattttgg
    21121 aaagccatgg gcttgacacg tgttgtttta gctcgcgagg ttaatatggc cgagttagca
    21181 gaaatccgta agcggacaga tgtggaaatt gaagcctttg tccatggagc catgtgtatt
    21241 tcttattcag gccgctgtgt tttgtcaaac cacatgagtc accgtgatgc caataggggc
    21301 ggctgctcac agtcttgccg ctggaagtat gatttgtatg acatgccatt tggaggagag
    21361 cgccgctcct taaaagggga aattccagaa gactattcta tgtcctctgt tgacatgtgt
    21421 atgattgacc atattcctga cctgattgaa aatggggttg atagcttaaa aattgaaggc
    21481 cgaatgaaat ctatccacta cgtctcaacc gtaaccaact gttacaaggc ggctgtagat
    21541 gcttacatgg aaagcccaga agctttttat gctatcaaag aggaattgat tgacgagttg
    21601 tggaaggttg cccagcgcga gttggctaca ggtttttatt atggtatccc aactgaaaat
    21661 gaacaattat ttggtgctcg ccgcaaaatt ccacaatata aatttgtcgg agaagtagtt
    21721 gcctttgact cagctagcat gacagcgacc attcgtcagc gtaatgtcat catggaaggc
    21781 gatcggattg aatgttatgg accaggtttc cgtcattttg aaacggttgt taaggactta
    21841 catgatgcgg atggccaaaa gattgaccgt gccccaaatc caatggaact cttaaccatc
    21901 tctttaccga gagaagttaa gccaggggat atgattaggg cttgcaagga aggccttgtc
    21961 aacctctatc aaaaagatgg caccagtaaa actgttagaa catagtaaca agaaatacta
    22021 gaggccctct ttttccaaat ggtatacgac catagttggg aaaagagagc ctgttttttt
    22081 tgaaaattgg atatcacaat agcttatttt ctcaaaactt gatagaataa taggagaatg
    22141 agtcataaaa aaagtgaaaa aaagatgatt ttttccactt taatttcgaa tagtatagat
    22201 gaggaggaaa actaatggca gaatttacat tcaacattga ggaacattta ctcaccttat
    22261 cagaaaatga taaaggttgg acgaaagaat tgaaccgcgt cagctttaat ggcgcagaag
    22321 cgaaatggga tatccgcacg tggagtccag accatacgaa aatggggaaa ggcattactc
    22381 ttactaatga agaatttaaa accatcttag acgcttttcg taagtaatgt taccttaatc
    22441 gaaacataat ccctcgttcg cccttgtcct cttaacctgg tgatgacatc gctaggttaa
    22501 gaggacaggg gcgaatagaa ggattatttt tttgaattga ggcgatcagc aaggccgaca
    22561 agtaccaaaa ttaagcctag cccaagaaaa atccatttgg cagctaaaag gccataaagc
    22621 aagaagatag tagcactaat gtaggagata tattctttgg tcatcttgtt aagtcacttt
    22681 ctataagcta ctgttaataa accagtcttc atggtaatga agactggtta gagataataa
    22741 aacgttatgt tatattgtca cttatcggtt ttaagatatg aatacaaatc ttaaaaaagt
    22801 taaggtttca tcgttgggaa taaaagcaca tctctgattg ttgttgtgtt tgttaataac
    22861 atgcaaagac gatcaatccc gattccgagt ccaccggttg gcggcatacc atattcaaga
    22921 gcttcaacga agtcgtagtc aatgccagtt gcttcgtcat caccaagttc tttagcttgt
    22981 gcttgtgctt caaaacgaga taattggtca atgggatcat ttaactctgt gaaagcattg
    23041 gcgtattctt tggtcatgat gaaaagttcg aagcggtcgg tgaagcgggt atcttctgga
    23101 ttcttcttag ccaaaggtga tacttcaaca ggatgaccaa agacaaaggt tggttggacc
    23161 aaggtttctt caacgaattc ttcgaagaaa gcattgatga tatgtccgac acttgtgaag
    23221 tgtttttcga gtgggacctg tttttctttg gcaagtgcaa tagcttcttc gacagtcatt
    23281 tcaggccaga aatcaacacc tgtcacttcc ttgatagcat ctaccatgtg gacacgtttg
    23341 aaaggttcat tgatacggat ttcagttcct tgataatcaa taggcccatc acctttaaca
    23401 gctttagcag catgttggat aatgccttct gtcaggttca tgatatcaag atagtctgca
    23461 taggcttggt aaacctcaat agaagtgaac tcaggattat gagtagcatc cattccctcg
    23521 ttacggaaga tacgaccaat ttcatagaca cgttccatac caccaacaat caaacgtttc
    23581 aaatgaagtt ctgttgcgat acgaagcacc atatcaatgt tttgagcatt atggtgagta
    23641 acgaaaggac gagcagcagc accaccagcc tcgttatgaa gcacaggcgt ttctacttct
    23701 aggaaatcaa gaccgtctaa ataacgacgg atttctgaaa tcattttgga acgggtcacg
    23761 aagcggtcaa agctttcacg atttgaaatt aaatcaaggt gacgcttacg gtaaatggtt
    23821 tcaatatcag ttaatccgtg gaatttttca ggaagaggac gaagtgattt agaaaggtga
    23881 gtcaacttgg ttgccttgat tgacaactcg cccatgtctg tacgcatgac ttcgccttca
    23941 acgccgataa agtcgcctaa atcggctttt ttgaagattt catagttgtc ttcgccaaca
    24001 gagtccttgc gaacataaag ttggatttgg ccttcacggt cttgaagatg agcaaaacca
    24061 accttacctt tgccacgttt tgtcatcaag cggccagcaa caatagctgt ttcgtttaac
    24121 tcatgtaatt cttcttttgt tttatcagca tacttttctt ttaattcagc agaattggct
    24181 gtgcggtcaa agcgtttacc gaaaggatca attccttgtt cagccagagc catcatcttt
    24241 tcacgacgga caatctgttg gtcatttaat tcttcgatgt gttgattaga catattttcc
    24301 tccaatacga tttcctttcc attgtatcat aaaagaggct agaatacacc tatatttcgt
    24361 tggaaaatgc gactgcagcg gggcactttt ttgaaaataa aattgaaaag cctaatggaa
    24421 aatagtataa tgattgggat attaaactag aaaagaaaag agactcatga ttactgctat
    24481 tgtttttgat gtggatgaca caatttacga ccagcaagcg ccttatcgaa tcgccatgga
    24541 aaagtgcttc ccagattttg atatgtcagt aatgaatcaa gcttatattc gctttcgtca
    24601 ttattcagat gttggattcc caagagtaat ggcaggggag tggaccacag aatatttccg
    24661 attctggcgt tgcaaggaaa cactgcttga gtttggctat cgagaaatcg acgaagctgc
    24721 gggagtacat tttcaagaag tctatgagca cgaacttgag aacattacca tgttagatga
    24781 gatgcgcatg acccttgact ttttaaaatc aaagaatgtt cctatgggga ttattaccaa
    24841 tgggccaaca gaacatcagc tgaaaaaagt tcgtaaatta gggctttatg attatattga
    24901 tcctaagcat gtcattgtga gccaagcaac aggttttcaa aaaccagaaa aagaaatttt
    24961 taacctggca gcagaacaat ttgacatgaa tccacaaacc acactatatg ttggggactc
    25021 ttatgacaat gatatcatgg gtgcctttaa tggtggttgg cattccatgt ggtttaatca
    25081 tagaggtcgt cagctaaaac caggaactaa gcctgtttat gatgtggcta ttgataactt
    25141 tgaacagctc tttggtgccg ttaaagtact ctttgattta cctgataata aatttatttt
    25201 tgatattaat gacaagaaaa atccgatttt acagatggga atcaataatg gcttgatgat
    25261 ggcagcagag cgtttacttg aaagtaacat gagcattgac aaagtggtta tcttgcttcg
    25321 attaaccaag cagcaagaaa aagtgctacg tttaaaatat gccaaataga tgaaaccata
    25381 atagcccact agataataat aaaaaaagct agcaaagtga gtgtcttgtc agtaagaaat
    25441 caatgtgtta gcttttttta ttattgtcta gtggttttac acctctataa aagatttatc
    25501 attccaaatt aaacagtcat aagttaaata atccttagtt tcaagaatag taagactggt
    25561 attatctaag ccacctttag cgagtaaaag agcaggttca aaacctaata atgagcgaat
    25621 agttgctgtt aagttagcgc cgtgtcctac aataagaacg ttttgataat gtttatcttt
    25681 aaacgattgg ataagatggc agacacgttg agtcgtttgg taaattgatt cagcctcgaa
    25741 ctgatctggt ttgaactggg ctagattctc ccgaaaagcc agcatttgtt ggggatatat
    25801 agctgccatt gttgctattt tagccccttc caatttacct aatctccact cccgaagctg
    25861 gtcggtgtgg taaagttttg gctgttggtc aaaagcatct aagataatag ctgctgttgc
    25921 catagctctt tgaaggtcgc tagtataaac ggcatcaaaa tccaccttag ctaactcttt
    25981 gccaagtaag tgaatttcgt cttttgcctc ttcaagtaat ggcgaatcgc ccccagcgcc
    26041 ttgaaagcga ccttctaaat tccaaagggt tttcccatgt cttacaaaat ataatttcat
    26101 ttaagcctcc ttttagagat aactgatgcg agcgctaaaa ataaaaaagt aaccagaaaa
    26161 agtttaggca taaccaagca aaaataatac ctatagtgaa aagataaagt aaaaaagcgt
    26221 agtataagtg tataatagct aggttctgat taaagtgtaa agcccatatt agatttaaga
    26281 caaatcgacc tgaatttgtc gtgatatcaa gcctttacaa aagaaaaaga ttaacaggat
    26341 caatgttaaa gcagttgaga tcaaaataat actaaacaaa gactagctta atcaaggcga
    26401 aaaacttaaa aaagaaacca gataaagttg gcagtagtgt tcattttctc ttctttaaat
    26461 cagcaaagct tgcgccaacg aaatcagcta gagcctggct agaaatcttt atagaacgcc
    26521 caacttcacc agctgaaacg attatttgac ctttttccag tgcagtttgg tcaataaaaa
    26581 taggatatga atgtttttga cgaatcccaa caggattatt ggcaccgtga atatagcctg
    26641 ttgtcttttg caagtctttt tgaggaacca tggacacttt tttgttacct gatacttttg
    26701 ccaattgttt ttctgataag tgttctgtta atggaataat gccaattaga ggacctgttt
    26761 gatcaccagt cagagcaagt gtcttgtaaa tatctgatgg ttgaagatca tctggaaagt
    26821 cgccttctaa agcattaagc ttgagtcctt gatgagcaat attagcctta tcgaggattt
    26881 gttctactaa ggtttttttg agttttgttt ttttagccat atcaagtcct tacctttatc
    26941 taaacataaa aaaatggtat aacaacatta ttataccatt tttttaatgt aagattcaaa
    27001 tgactaaaaa ttagtctttg ggatcaaata attgaggatg aattggtaaa gcaatcatta
    27061 acgctaaaca tgttattaaa aaagttagga caccagctgt accattaacg ctaaaagaat
    27121 accagacagc ggacatgcct ttaggggcgt aactgcccca gaaaatgatt cctgcaagga
    27181 agtgccacaa gtaacgtact gtaacggcta gtaaactagc cattattgca agaaaaacgg
    27241 caaaaaaggt ttgttgtctt cttaaagttt taatcaaact atcagagaaa ctaccggcta
    27301 atcccataga ggtaaaggct aagatatatt caataaagac ttgggacatg ctgagatagt
    27361 aaacttttcc aagtacaaag tgaagtagcc cccaaatgag acccgccaac atgccgtact
    27421 ttaacccacg gcgcaaagag aaaataacca gtgcaatagc accataagaa ggactaaacc
    27481 agccagcaaa atctggaata aatgaaaggg tcatcgccaa tgcagcaaaa atagcagctt
    27541 cgataaggta tttgacattg gtgtttggtg acataaaaaa ctccttttgt gcacaaaaag
    27601 agtatcgctt tccaatcatt gattattggt cacaatccct acgcttgtac taacaagatc
    27661 aggtcctcag gatttcgcaa ttgcgatctc agccaaagca ctcctttgtg aaatattata
    27721 gtgctttcat tatatgatga gataatctcc ttgtcaagga taaggggttt taaattattg
    27781 acctagagtt tttcttggta agatgtaaac tataaaaaaa gattagccat gatgctaacc
    27841 tcttaattgt tggagttgcc aaataacttc tcaaacgttt ttttagtgtc ttttgttacg
    27901 gcaatttgat ttaaatctaa agcattgtta aaaccactga gataaccttg tgaggtatat
    27961 tggtgtaaat cgtaatctaa ggttgtatta ggagcagcct cataatagcc agaatcacta
    28021 ccataagtcg gaatccatac agcatcgaaa ccttttgttg aaatatcttg ttctgccata
    28081 aaataagttc caatatagag accaacattt tcagcaccaa gttttttaag ctcttctcgg
    28141 aaggctgtta cgcctttatt catatctttc atagtggctt cttcgacatc aatccagtag
    28201 taagttggat tatagggagc agcgtttttg tagaaagctc gggcctcttc tttcatctct
    28261 ttagtactac gaccaagtgc gtaactgtaa acagctacag gaacatttcg tttttgaaat
    28321 tctttgatat gcgttttaaa agatttgtca attccagttg taaaagcagc gttgttatga
    28381 gctgtaattt gcgatcctcc atagacacgt acaattgcgc cagagatgtg acgtgacaat
    28441 gtgtcataat caatttcttc agggagttgc cagccggaaa catcaacaat aggatttaaa
    28501 ataaagtctt cggtttcaga agtgctagtt tttgctttac taggattact ggttgcaata
    28561 ggaatatgac tcttagcgtc ttcaacttct ttttgtttcg catgattagc ttgtcttttt
    28621 ccgataatca ataccattgc cagtaaaata aagaagacta gcacaacaat aggttttatt
    28681 tttcttctca ttaactgtta ttgtacccta attactaaaa aaaatcaaaa tatcctaact
    28741 gttttcttat attgtcttgc attttaaggt attatctttt agaagttaca aatgagatcc
    28801 tctctaacta tgtcaagttt atgtcactat ctcttatagt tggtagctat attctttact
    28861 atattagttt agtctttgac tatatcatga cagtcagcaa gtactgtttt gttatttaat
    28921 tctcatgtta ttatcatttg ataaataagt gagcttcaaa ctggtaaacg ctctgtaaat
    28981 ctgtcataat agagaaaaaa acgaggaaga agtttatgtc agctaagctt atgagtcgca
    29041 ttgctatcat gtcagcccta tgtgttgtgt tgagaatggt ttttagcagc ctgcctaacg
    29101 tgcagcctgt gacggcattt ttactcagtt atcttcttta ctttgggtta gccgaggctg
    29161 tattagttat gatgttgtgc ttatttttat cagccttttt gctgggattt ggtccttggg
    29221 tcttttggca agttacttgt tttgtgcttg ttcttttatt atggcgtttt gccttgtacc
    29281 ctctgtctca gcaattcccc aaatatcagc ttggctgtca ggctttcttg gtcgccttat
    29341 gtggcctcct ttatggggtg ttgatagata cttgttttgc gtatttgtat agtatgcctt
    29401 ggtggagcta tgttctagct gggatgcctt ttaatatagc gcatgcttta tcaactctcg
    29461 tcttttttcc agttgtgatg atgttattta ggaggttaat cggtgaacaa aagatttaaa
    29521 acaggatttc tagcgcttgt tgctatgcta cttgttgctt gctcgcaagg aacaaaacaa
    29581 acacagactc caagcgttcc aaaagcagac catcacgttc gcttagttgt caaagaagat
    29641 accaatacca ttgatgaaaa agtttctttt ggaaaaggag atacggtgct tgagattctc
    29701 aaagataatt atgaggttaa agaaaaagat ggttttatca cagcaattga tggtatcgag
    29761 caagacacga aagctaacaa atactggctt tttaaggtca atggaaagat ggcagataag
    29821 ggtgccgatc aaattaccgt taaagatggt gatagcattg aattttatca agaagttttt
    29881 aaatagtaac tataatataa aatagacttg gcacgccaag tctattttat attaaccaag
    29941 aagtgcttta aggtcttctt caattagttt aggatctgtc tttgaggaat agcgtttaat
    30001 gacttgacca ttttggtcaa tgagaaattt agtgaaattc cattcgatgc gtttcccaag
    30061 gggaccactt ttttcttctt ttaaccaggt gaacaaagga tcagcgtctt taccattcac
    30121 tttgatttta gcaaagcgag ggaaagtagt gtgataggtc agactgcaaa agtgattaat
    30181 ctcctcagca tctcctggag cttgatttaa aaattggttg caaggaaaat ctaagacctc
    30241 aaatcccttg tcatggtatg tgtcatatag tgcttgcagg gcctggtatt gtggggttaa
    30301 tccacacttg gtagctgtgt taacaatcaa aacaaccttt tttttataag cagctaagga
    30361 aacgtcattc ccgttttgag ccttaaccgt aaaatcatag agattaggca tgtgacatct
    30421 cctcggtgta attgataatt tggtcaacgg tatcactcaa gaattgaatg gtatctcgaa
    30481 gaggcttttc ggtggcaatg tctgccccaa tgagcattgc agtatcaaga ggcgtacggc
    30541 tgccacctga ttttaggaag tcaagccatt cttttgcccc atctgggttg tttttaaggt
    30601 taaggtaacc agctgttgac ataacaagcc cagcagaata ggtataacta tataagccca
    30661 tgtagtaatg cgcttggcgc atccaggtaa gagctgcgtc atcgtcaatg tcaacggcat
    30721 ctccccagaa gtctgttaag acctctttca tcattgcatt taattggtca gctccaaagg
    30781 taccgccttc ttcaatcagg gtgtaaacct tacgttggaa agccgcttcc aataggtgag
    30841 tgatgaagtt atgaaagtaa gtatctgtta aacggtgagc aagagcaaaa cgtttttgac
    30901 gagggtcatc aaactgatgt tccaagtaat cactaagcat caattcatta aaggtcgatg
    30961 gcgcttcgac gtaataagtt gacatatggg tgttgaagta actttggtga ttatctgaaa
    31021 aaatgaattg accagagtga ccgatttcat gaataagggt ataaacatca gacattctgc
    31081 cagtccaact cattaagaca tacggatgaa ccttgtaggg atcagcggca tagccaccag
    31141 aatccttatt ggcgttagca gcaaagtcaa cccagcgttc tgtctgataa cgttcgattt
    31201 ctttcgtgta ttcttgccct aatggggcta gagatttcat cacgaggtca taggcaccat
    31261 caatgctgac ctctggattg agctcattat caatatctag tttccaatca gcaaaagtca
    31321 ttttctcaag accattgact tgggcgacat gttttaagaa tttctgagca accggtccaa
    31381 attcagtcat gatgagatca atttggcggt cgaacaagct acgatccact tcctgttcag
    31441 ctaggaggta atcaaagaca gaagcgtagc ctttcatatc cgctaacaat ttttcagatt
    31501 taaccttggc taagtaagcc gctgcagctg tattttggtg tttacggaga ccttttgaaa
    31561 aagagcggaa ggctttttca cgaatctcag cattttcgtg attttgatag aaattttcgt
    31621 aagaaacaaa gctattttta taggttttac catccacctc aaaatcctcc atgtcaaagt
    31681 caccagcccg cattttggtg taaatatcat agggcgcatt gataacctcg cgtaagttag
    31741 ccaaagcttt ttctacatca ggacttaaga ggtgttcttt ttgaattttt gccatgcgaa
    31801 tagctgcgct gaaataaggg ttcttttcta atgtatctaa cacgtcaagg tcggcattgg
    31861 ctaaggcggt gtcaaagaag ctaagggcaa cgctagcttt agtcatgaaa tcatcgccag
    31921 cctgagcaat ttgagcaaaa ctttcatctg aaaagtcagt ggtttgaggc ataaaggcat
    31981 aagtaccaat atgactcatt tgaatataaa tatgctcaat ttctattaag gcctgagtga
    32041 aatcgtccac tgatgttaag cggccttcat aattgcgctt aaacaggtca atatcttgta
    32101 aggttttttc aatagcgagt aaaaaatctt ggcggtcttt gtagagcgct gttagatccc
    32161 aaagttcatt ttcagggaat tctgaacgtt ttttcaattc catagttgtc tccttaacaa
    32221 tatagtcaag actagtataa cagaatttta gtggaatatg gagactaaac ctatccaaac
    32281 attctttaaa ataaagcgct tacttttgtt aaaaaacaaa cgttatgaac atgatcactt
    32341 ttatttttgg taaaaagtgg tatgatagaa gaaactagca aagaaggaga tggtcatttg
    32401 ccacttaaaa agttagagag tagtaacaat caagctatca ttgctgaaga agttgctctt
    32461 ttgaaagaaa tgttggaaaa tatcacacga cggatgattg gagatgacgc gtttacagtt
    32521 atcgagtcta ttatggtgtt atctgaaaaa caagattaca tagaattaga aaaagttgtc
    32581 gccaatattt caaatcaaga aatggaagtg atttccaggt atttttctat tttacccttg
    32641 ctaatcaata tttcagaaga tgtcgattta gcctatgaaa ttaattatca aaataatacg
    32701 gatactgatt atttaggaaa attagcccta accatcaagg atcttgctgg aaaagataat
    32761 ggtaaagaca ttttggagca ggttaatgtg gttcctgttt taacagcaca tccgacgcaa
    32821 gtacaacgta aaacgattct ggaattgaca actcacattc ataaacttct gcgcaaatac
    32881 cgtgatgcta aggctggtgt gattaatctt gagaaatggc gtcaggagct atatcgttat
    32941 attgaaatga tcatgcagac agatattatt cgcgagaaaa agcttcaggt gaaaaacgag
    33001 ataaaaaatg tcatgcagta ttacgatggt tctctcattc aagcagtgac caagttgaca
    33061 acagagtaca aaaacttagc ccaaaaacac ggtctagagt tagacaatcc caaacccatt
    33121 accatgggga tgtggattgg tggggaccgt gatgggaacc cctttgtcac agctgaaacc
    33181 ttgtgcttgt cagctacggt tcaaagtgag gttatcctca attactacat tgacaaatta
    33241 gcagcccttt accgaacatt ttcactgtcg tcaaccttgg tacaacccaa ctcggaagtg
    33301 gaacgtttag ccagtttgtc tcaggaccaa tcgatttacc gtggaaatga accttatcgc
    33361 agagcttttc attatattca atcgcgtctt aaacaaacac aaaatcaact aactaatcag
    33421 ccagcagctc gtatgagtag tagtgtggga ctaaacacat ctgcttggtc ctcaccagct
    33481 agtttagaaa atcccatctt agcctatgac tctcctgttg attttaaagc tgatctaaag
    33541 gctattgagc agtcgctact tgataatggc aactccgctt tgattgaggg ggatttgcga
    33601 gaagtcatgc aagctgttga tatttttggc ttcttcttag caagcattga catgaggcaa
    33661 gactccagtg tccaagaagc ttgtgtggca gagttattaa aaggagccaa tattgttgac
    33721 gattatagct ctctttcaga aactgaaaaa tgcgatgttc tcttacaaca attaatggag
    33781 gagccaagaa ccttatcctc ggcggcagtt gctaaatcag acctattaga aaaagaactg
    33841 gctatctata ctacggcacg agaattgaaa gataagcttg gagaagaggt tattaagcaa
    33901 catattattt cacatacaga aagtgtctct gatatgtttg agttggccat catgcttaaa
    33961 gaagtgggat tggttgacca gcagcgggct cgtgtgcaaa ttgttcccct ctttgaaacc
    34021 attgaggatt tagataatgc ccgtgacatc atggcagcct atttaagcca tgacattgtc
    34081 aaatcttgga ttgcaacgaa tcgtaattac caagaaatca tgttaggtta ttctgacagt
    34141 aataaagatg gtggctactt ggcatcgggt tggactcttt ataaagctca gaatgaatta
    34201 acggctattg gtgaggaaca tggagtgaaa atcaccttct tccatggtcg tggaggaaca
    34261 gttggtcgag gaggtggccc ttcttatgat gccattactt cacaaccttt tggttccatc
    34321 aaagatcgga ttcgtctgac agagcaaggg gaaattattg aaaacaaata cggcaataaa
    34381 gatgtggctt attaccattt agaaatgttg atttcagctt ctatcaatcg tatggtgact
    34441 caaatgataa cagatcctaa tgagattgat agttttcgag aaatcatgga tagcattgtt
    34501 gctgatagca ataccattta tcgaaaattg gtttttgaca acccccattt ctatgattat
    34561 ttctttgagg caagcccgat taaggaagtt tccagtctca acattgggtc aagaccagca
    34621 gcccgtaaaa cgattacgga aattacaggc ttgcgtgcca ttccttgggt cttttcatgg
    34681 tcacaaaatc gcatcatgtt cccaggttgg tatggggtag gttcagcctt taaacgttat
    34741 attgaccgag cacaaggtaa ccttgaacgc ctccaacaca tgtatcagac gtggcctttt
    34801 ttccattcct tgttatcaaa tgttgatatg gtattatcta aatcaaacat gaatattgcc
    34861 tttcagtatg cacaactagc tgaaagtcag gatgttcgag atgtttttta tgagattttg
    34921 gatgagtggc aattgacaaa aaatgttatt cttgctatcc aagaccatga tgatctattg
    34981 gaggataatc cttcccttaa gcatagcttg aagtcacgct tgccgtattt taatgtgttg
    35041 aactatattc aaattgaatt gattaaacgt tggcgtaata atcaacttga cgaaaatgat
    35101 gaaaaattga tccatacaac tatcaatggc atagcaactg gtttacgtaa ttcaggctaa
    35161 tgctcttgag tattaattgg tatttataga agttttcaag tgactaatca gaattttaaa
    35221 ggttagccct tggagcttct tttttgagga ttcttgactt ttccttttgt ttgatataga
    35281 aagatgttat aatgctaaat gattatctca agaagtagag ggaaaactat gaagattgat
    35341 aaaaggcacc tcttaaatta ttctatatta ttgccttatt taattttatc ggtgataggc
    35401 ttaataatgg tttactcaac cacaagtgtc agcttgattc aagcacatgc taatccattt
    35461 aaatcggtga ttaaccaggg agttttttgg ataataagtc tagtggctat tacatttatc
    35521 tataaattaa aattaaattt tttaacgaat acaagggtat taactgtggt tatgttagga
    35581 gaggcctttc ttttaattat tgcccgcttc tttacaactg ctatcaaagg agcgcatggt
    35641 tggattgtga tcggaccagt cagctttcag cctgctgagt atttaaagat cattatggta
    35701 tggtatttgg cattgacctt tgctaagatc caaaaaaaca ttagccttta tgattatcaa
    35761 gcactaactc gtcgaaaatg gtggccaaca caatggaacg atttacggga ctggcgtgtt
    35821 tattctttgt tgatggtact tttggttgct gctcagcctg acttaggaaa tgcttccatt
    35881 attgtattga cagccattat tatgttttct accagtggca ttggttaccg atggttttcg
    35941 gctatcctag tcatgattac cggtctatcc acggtctttc ttgggactat tgccgttatt
    36001 ggggtagaaa gagttgctaa gattcctgtt tttggctatg tcgctaaacg ttttagtgcc
    36061 ttttttaatc cttttcatga cttgaccgat tcaggtcacc aattagccaa ttcttactat
    36121 gctatgagta atggtgggtg gtttggccaa gggttaggaa attccattga aaagcgtggc
    36181 tatttgcccg aagcacagac agactttgtc ttttcagttg tcattgaaga gttaggtcta
    36241 ataggagcag ggtttatttt ggcacttgtt ttcttcttaa ttttacgtat tatgaatgtt
    36301 ggtattaaag caaaaaatcc ttttaatgcc atgatggctt taggagtagg cggtatgatg
    36361 ctcatgcaag tctttgttaa tattggtggt atctcaggct taattccatc tactggtgtt
    36421 accttccctt ttttgtctca aggtggaaat agcttacttg tcttatctgt tgcagtgggt
    36481 tttgtactaa atattgatgc tagcgaaaag cgagatgata tatttaaaga agctgaatta
    36541 tcttatcgaa aggacactcg aaaagaaaat agtaaagttg taaatatcaa gcaatttcaa
    36601 taatattcta aaatctcctt taaggagatt ttagaatata gacaatccca gtttgatgct
    36661 caaaaaactt gaactgctct gctgatttct tatttttgcg tgtgacatga gcccaaacag
    36721 ctgctttttg ctgtggcaaa aataaggtgt ggaattccaa aggaa
//
LOCUS       DAUGUF010000020        35608 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUGUF010000020 DAUGUF010000000
VERSION     DAUGUF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35608
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.020"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(14..628)
                     /locus_tag="VIB71_000968"
     CDS             complement(14..628)
                     /locus_tag="VIB71_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEQ8822714.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            720..1067
                     /gene="ssrA"
                     /locus_tag="VIB71_000969"
     tmRNA           720..1067
                     /gene="ssrA"
                     /locus_tag="VIB71_000969"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            1369..1989
                     /locus_tag="VIB71_000970"
     CDS             1369..1989
                     /locus_tag="VIB71_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEQ8822715.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(2246..4510)
                     /gene="glgP"
                     /locus_tag="VIB71_000971"
     CDS             complement(2246..4510)
                     /gene="glgP"
                     /locus_tag="VIB71_000971"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEQ8822716.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAVQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHVKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(4545..6038)
                     /gene="malQ"
                     /locus_tag="VIB71_000972"
     CDS             complement(4545..6038)
                     /gene="malQ"
                     /locus_tag="VIB71_000972"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEQ8822717.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDLLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEGQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(6153..7172)
                     /locus_tag="VIB71_000973"
     CDS             complement(6153..7172)
                     /locus_tag="VIB71_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ8822718.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISP"
     gene            7416..8663
                     /locus_tag="VIB71_000974"
     CDS             7416..8663
                     /locus_tag="VIB71_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8822719.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALIGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            8937..10298
                     /locus_tag="VIB71_000975"
     CDS             8937..10298
                     /locus_tag="VIB71_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8822720.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIDLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            10298..11134
                     /locus_tag="VIB71_000976"
     CDS             10298..11134
                     /locus_tag="VIB71_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ8822721.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            11321..12095
                     /locus_tag="VIB71_000977"
                     /pseudo
     CDS             11321..12095
                     /locus_tag="VIB71_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12609..13592)
                     /locus_tag="VIB71_000978"
     CDS             complement(12609..13592)
                     /locus_tag="VIB71_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ8822722.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(13623..14873)
                     /gene="dltD"
                     /locus_tag="VIB71_000979"
     CDS             complement(13623..14873)
                     /gene="dltD"
                     /locus_tag="VIB71_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEQ8822723.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(14866..15105)
                     /gene="dltC"
                     /locus_tag="VIB71_000980"
     CDS             complement(14866..15105)
                     /gene="dltC"
                     /locus_tag="VIB71_000980"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEQ8822724.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(15123..16379)
                     /gene="dltB"
                     /locus_tag="VIB71_000981"
     CDS             complement(15123..16379)
                     /gene="dltB"
                     /locus_tag="VIB71_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEQ8822725.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNLP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(16376..17914)
                     /gene="dltA"
                     /locus_tag="VIB71_000982"
     CDS             complement(16376..17914)
                     /gene="dltA"
                     /locus_tag="VIB71_000982"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEQ8822726.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(17926..18069)
                     /locus_tag="VIB71_000983"
     CDS             complement(17926..18069)
                     /locus_tag="VIB71_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEQ8822727.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            complement(18333..20324)
                     /gene="uvrB"
                     /locus_tag="VIB71_000984"
     CDS             complement(18333..20324)
                     /gene="uvrB"
                     /locus_tag="VIB71_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEQ8822728.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            20517..22691
                     /locus_tag="VIB71_000985"
     CDS             20517..22691
                     /locus_tag="VIB71_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ8822729.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            22691..23431
                     /locus_tag="VIB71_000986"
     CDS             22691..23431
                     /locus_tag="VIB71_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822730.1"
                     /translation="MTELKIDVQGLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            23589..25076
                     /locus_tag="VIB71_000987"
     CDS             23589..25076
                     /locus_tag="VIB71_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HEQ8822731.1"
                     /translation="MLHKEKPDYNRNQYGFYTLDQIVPDEHFLRQVEAVIDFDFIYDL
                     VEDTYSSDNGRPSLDPVMLVKIPLIQCFYGIRSMRQTIKDIEVNTAYRWFLGLTLDNK
                     VPHFTTYGKNYSRRFQEKGLIESIFTHILGLCINTGLIDPMEIFIDGTHIKAAANNRK
                     FINREVEKQAKFMSEQLEIEINRDREKHGKKPLGPVAKKISTTDPESGWFHKGDHKEV
                     FAYSAQVACDKYGWALAYSVEAGNIHDSQAFPALFAKLEPLKPQFIIADSGYNIPSIA
                     KFLIDKEITPVLPYTRPRGKKDLLRPKEFIYDEHFECVICPEHQALTYRTTTREGYRE
                     YKSDPAICANCPLLSVCTTSKNRQKVVTRHIWKDYLEQCEDIRHQRGMKELYQHRKET
                     IERLFGTAKEYHNLRYTREKGKSKMEDKVGLTLACLNLKKRVKRMVGEPFYFVQMRWF
                     KHGNRHFYLKTLKKTNTKSMFVFNLRQGNRFPCLFWLLLLFKPAK"
     gene            complement(25125..25277)
                     /locus_tag="VIB71_000988"
     CDS             complement(25125..25277)
                     /locus_tag="VIB71_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822732.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYSHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(25274..26653)
                     /locus_tag="VIB71_000989"
     CDS             complement(25274..26653)
                     /locus_tag="VIB71_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8822733.1"
                     /translation="MSHFSDKFMDISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGGSSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(26831..27280)
                     /locus_tag="VIB71_000990"
     CDS             complement(26831..27280)
                     /locus_tag="VIB71_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEQ8822734.1"
                     /translation="MIISAEGDVSVHHCFEAMLISLQEDHRQNTLRQLSRDDIKAGIN
                     YVKHYSKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANHFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(27277..27612)
                     /locus_tag="VIB71_000991"
     CDS             complement(27277..27612)
                     /locus_tag="VIB71_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8822735.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAIELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(27615..27926)
                     /locus_tag="VIB71_000992"
     CDS             complement(27615..27926)
                     /locus_tag="VIB71_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8822736.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(27949..29943)
                     /locus_tag="VIB71_000993"
     CDS             complement(27949..29943)
                     /locus_tag="VIB71_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ8822737.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRYKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(30049..31143)
                     /locus_tag="VIB71_000994"
     CDS             complement(30049..31143)
                     /locus_tag="VIB71_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEQ8822738.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAEQSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEKIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQITLKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIDPS"
     gene            complement(31152..32552)
                     /locus_tag="VIB71_000995"
     CDS             complement(31152..32552)
                     /locus_tag="VIB71_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ8822739.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEVIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            32777..33472
                     /locus_tag="VIB71_000996"
     CDS             32777..33472
                     /locus_tag="VIB71_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEQ8822740.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            complement(33477..33635)
                     /locus_tag="VIB71_000997"
     CDS             complement(33477..33635)
                     /locus_tag="VIB71_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822741.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(33704..35017)
                     /gene="obgE"
                     /locus_tag="VIB71_000998"
     CDS             complement(33704..35017)
                     /gene="obgE"
                     /locus_tag="VIB71_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEQ8822742.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDEADLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD"
     gene            complement(35074..35202)
                     /locus_tag="VIB71_000999"
     CDS             complement(35074..35202)
                     /locus_tag="VIB71_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEQ8822743.1"
                     /translation="MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM"
BASE COUNT        11126 a         7237 c         6264 g        10981 t
ORIGIN      
        1 ttaacaccaa accttaatgc tgtaagaacc aagatataac atcttttcca aaaataaata
       61 aataactgta gccgataata gaaattggtt tagttattaa aagaatagtt acaaagcgct
      121 ttaaagacat gtccgtcaat cccgtaatca taaccataat atcagctgga gaaacaggcg
      181 atgccataca aaaaataaat aatttttcat atcctggtgt ctccaaacgc ctttcatact
      241 tgtaaaatgt tttgtcattt acaaagagta agataaattt acgaccataa gtcttaacaa
      301 gcaagaagag gactatactg ccaataatga tgcctacata attataaata aaacctgtta
      361 cagggccaaa gattaaaaaa cctgcaactg tcgtaaggcc tccaggaatc acaggaaaaa
      421 caatctgtat gatctgcacg acaataaaaa caaacggccc ccataatcta tagcgctgca
      481 ctaagtcttt aagagcatta ctatcgttta atatacctag tctatacagc caaaaagcga
      541 ggaaaaaagt accaattagt gcaataattc ctaaaatttt gataattttt tgccataata
      601 tataggcttt tgaattacgt tttgtcatag actaatcata ccataagctg taaaattttg
      661 ctatttaaaa aaagttttga tagaatagtt agtgtaagaa attggttaat tatctatttg
      721 gggttgttac ggattcgaca ggcattatga ggcatgtttt gcgtcccatc ggcagatgta
      781 aattgccagt taaatataac tgcaaaaaat acaaactctt acgctttagc tgcctaaaaa
      841 ccagctagtg tgacttctac aagattgctt gtgtcctgtt agaagtctca aaatagcaag
      901 ctacggttac gaaattgtct agtttcgtga caagagattg atagactcgc aaactaatgg
      961 cttgagttat gtgtctttag tttgttaaat gaagacataa cctatggacg tagacaaata
     1021 tgttggcagg tgtttggacg tgggttcgac tcccaccagc tccatccatg cttaccgtaa
     1081 gtaatcataa cttactaaaa ccttgttaca tcaaggtttt ttctttttgt cttgttcatg
     1141 agtttccgtt atccctatag tcataccatc acacttaccg atactccatc aataccactc
     1201 aaaaccttgt catatcagag ctttttgacc atttttttca tgaatatcta aaaaaaagaa
     1261 tcaaaatagt actaaattcc ccatagcgca tgcgttatgg ggaatcatag ctatatcttg
     1321 tttataattt atgatataat acagcaaaaa tagtttagga aataacgtat gacaaaaaaa
     1381 cacttactaa cacttcttct catctctttt tttactagct ttttggtagc ttgttcaaca
     1441 acgaaagata aagagcctca accgtctgat tcagaaatca ttactccccg actacaccaa
     1501 gccgctcatc aagataaacg cgctaacttt gaaaaaatta aacttgcgac tgttgattcc
     1561 tcatttacag gaggaacaag ccttgaagaa cttatttcac tctttggaga gcctagccaa
     1621 catgatccaa aaacagcagg cgaagtaaca atcgacgctt atacttggca gtttgatcaa
     1681 gttactctca ctgttaatct ttatcaaaat agtagtattg ttaaaaccat ctctaatttt
     1741 acctttgcaa gagagttagg cttatcgcaa aaggaatacc aacaattaca aaaaggaatg
     1801 tcttatgaag acgttaaaaa gatcttaaca gaacctgata attatagcca agcgtcatct
     1861 agtgatcatc aaactttgca agcgatttgg gttagtggct taaagacaga tacaagcgga
     1921 gctaatattt ctctcgtttt tgaaaataat cagttaacag aaatgtctca ggtaggactt
     1981 gaagaataaa aaatgagtaa tatattttgc taaaaagatt gatttcggtg tacatcgaaa
     2041 tcaatctttt tatatcattt taataaaaaa ctttagtgta gtttcttata attacctcca
     2101 tagatcgcta aacagacttg ctttacgctt aatgtaataa ttaacctaag tctgaagtaa
     2161 aatcataaga cagcagaaac tactgtctta tgatttagtt taagcatgtt acggtaccgc
     2221 taccccacat tgcaattatt attttttatc gtgaatgcca aatatcttcg ttatactgct
     2281 caatggtacg gtcagatgag aagaatccag cttttgcgat gttatggacc acttttgtca
     2341 tccataaatc ttggtcttca tagtctgcta acattttttc tttcacttca atgtactctt
     2401 caaggtcaat caaagtcatg aaccagtctt ttgaaatcaa ttctttataa agacgatcaa
     2461 gacgttcttc gttgccaaat gctagcaatt ctggactgat aataaagttc actgctgctt
     2521 taatagcagg atggttatca tagtaatctt ttgctacata agaagcagtc gcataaaggt
     2581 tgatgatggt gtcagaatct ttaccaaagg tgtagatatt ctccatgcct gcaagctcag
     2641 cgatttctac gttagcaccg tccattgtac caagtgttaa agcaccgtta agcatgaatt
     2701 tcatattacc agttccagaa gcttctttgg atgctagtga aatttgctca gaaatatcag
     2761 ttgctggaat caagtgctct gctactgtca cgttgtaatt ttcaactaga tgcacattaa
     2821 ggtatgggct tacttcaggg tcattgttaa tcaattcaga caagcaaagg atcaagtgaa
     2881 tgatgtcttg agcaatgatg taagcaggcg ctgctttacc tccaaagata acagtgattt
     2941 tacgttttgg aaggttgcct tttttaattt ccaaatattt gtgaatcacg taaagagcat
     3001 tcatctgttg acgtttgtac tcgtggaaac gtttgatttg ggtatcaata atagaatgtt
     3061 catcaagctc aatgtcttta ttgtctttaa ggtaacgttt aagagctaat ttgttgttga
     3121 atttgatttc agccaattta acatgaacag ctttgtcatc tgcaaaggcc atcaattttt
     3181 ctaattttgt tgcgtcagtc aagtactcat cgccaataag ttctttgatg taatcagcca
     3241 agtcttggtt agcaaattct agccaacgac ggaaagtaat cccgttggtt ttgttgttga
     3301 atttttctgg gtaaaggtca tagaaagctt ttaattcgct gtttttcaag atttctgtgt
     3361 ggagtgctgc taccccattg acacttgttg caaaatgaat atccatatgg gccatgtgca
     3421 cacgacctga ttcgtcaata atttgaacag ctgggtcaga cacttctgaa cgaacaagag
     3481 catccaattt ttcaatgatg gttaccaagt gtggcactac ttcgtttaag taagcagttg
     3541 gccatttttc aagggcttct gcaagaatag tgtggttagt gtaaccaacc atatttttca
     3601 caacagctac cgcttcatca aagtcaaagc catgtttttc agtcaagaga cgaattaatt
     3661 ctgggatgac cattgatgga tgcgtgtcat tgatttgcac gtaagcgtag tctgcaaggt
     3721 catgaaggtt tgaaccacgt tcgatagctt catcaatgat taattgcact gcatttgaca
     3781 ccataaagta ctgttggtaa atacggagca attccccatt tttgtcagaa tcgtctgggt
     3841 agaggaacaa ggtcaagttt ttagcaattt gcgttttatc aaatgaaata ccgtctttga
     3901 ttaatccgta atcaacgccc tcgatatcaa acaagttaag gtagttttta gtgtcgcgtt
     3961 tgtaacccaa aacatcaata cgatcaagac gagattttaa ggtaaagttt ttgaagggca
     4021 catcgtaaga aatgtctgtt ggaaccaacc atgagtcatc ttcaatccag tagtttggct
     4081 cagcttcttg ctcattgtgt ttgaagactt gcttaaacaa cccacaatga tagtttaaac
     4141 caaccccttc accattaata ccaagagatg aaatagagtc aatgaaacat gatgccaaac
     4201 gtcctaaacc accattccct agtgatggtt ctaattcaac atcttcgact tctgcgatag
     4261 atttgccagc agctgccaat tcttctttga tgtctttgta aattcctagg ttaatcaggt
     4321 tgtttgatag taatttacca atcaaaaact ctgctgagat atagtaaact ttgcgtttag
     4381 cagaattttt agccttgtgg ctagcttctt ctttgacaaa gtttaataat gatagataaa
     4441 tctcttcatt gctggcttgc gtaagtgatt ttcctagttt agtttcaaca tattctgtaa
     4501 agcgtgtcat gtcttcctct tttcaataat gtaacattta aatattatct tgcgcgacca
     4561 taaagatctg ttaaataaat aaggtagtct ttgtgatctt ggttcaattc accgtcaagc
     4621 atacgccatt gccaattacc tccaattgta tttggcatat tcatacgact cttaccatct
     4681 ttatctaata aatcttggat gcaaagaatg gctgtatcac aaacagaagc aaagattgtt
     4741 cttagcatgg cttttgtaat actttcatct gcatgtttgt gaagatagtt atttacaaag
     4801 tgtacttgtc cttcactaag attgtcatac catccgttaa ccacctcgtt atcatgagtc
     4861 cctgtgtaag cgacacaatt acggtcatag taatgtggca aatctatact ttgactcgtt
     4921 atatcaaata aaccaaattc taatatcttc atgccaggaa agcctgttga tgctaatagc
     4981 tgctctgctt tttcatcaat ataaccaagg ttttctgcga tgataggaag ctctcctaag
     5041 gcctcacgaa ccgcagaaaa taacgctata cctggggctg aggcccaatg gccatttcta
     5101 gcagttttat caccagcagg aatttcccaa aaatctgaga agcctttaaa atgatcgatt
     5161 cttagctgat catatagttt gaaactttct tgaatacgat aaatccacca tgcaaaatta
     5221 gacttttcat gagcagacca attgtaggtt ggatttcccc acagctgacc atcttcacta
     5281 aagccatctg ctggtacacc tgcaataaac aatggctttt tatcactatc tactttaaat
     5341 agctcaggca tcgtccaaac ttctacactg tccgcagaaa cataaatagg catatcacca
     5401 ataatttcta tccctttatg gttagcgtaa gttttcaagg ctgaccattg ttggtaaaag
     5461 aagtattgac agactttatg ataggtaatc ttttttgcaa gcaactcacg gtaattatta
     5521 agtgagtctt cttggcgttt aatgacagtt tcgtcgtccc aatcttgtaa ggctttattg
     5581 ttaaaatatt cttttaaagc cataaattca gcaaaatcag ttaaccagct agaagctgtt
     5641 tcaaaagctt ctaatttaca cacattttct tgttcagcaa caaaagctct cactgctttt
     5701 tctaaaagtg gacgcctaac ttgaaaaagc tgagcatagt ctactgcttc aggatttgtg
     5761 ccgaatgtaa tatcacacaa atctgctgct tctaaaagtt catcatctac tagcaattca
     5821 aaatcaatga aatgtgtgtt cccagcaata gctgaaaatg actgataagg agaatctcca
     5881 aaactcgtcg ttgttaaagg cagaatttgc caataggttt gtttcgtctc tgctagaaga
     5941 tcaacaaatt caaaagctga ttttccaaaa gtgcctatcc caaatttccc aggcagggaa
     6001 ctaatatgca ttaagatacc gcttgcacgt ttgttcatga tttttctcct tgtgaaatct
     6061 attcatgatg agattataac gcaagcgctt gcgtaagtca accagtttcc taaaaaaagt
     6121 aacattcctt aaaaatgcta ctttttttgt tcttaaggac taatatcacg aacgctttct
     6181 ctttgtttta aactaaaagg aacaaaaata gtctgactaa gattctgttc attggaattg
     6241 ataatatcaa gtaattgctt aaaagacatt tttccaagat tttcaacatt tatatcaaat
     6301 gtcgttaaat aagggtgaat taatttagcg taattagaat tattaaaagt gataattgac
     6361 atatcatctg gcacttttat atcataaaaa gataataact gtaccatacg aatagccaga
     6421 acatcaccaa caacaaccaa ggcagttgct ttaaaggaag atatagtttc catcaatatt
     6481 tctacgctaa caggatcctt acgatcaaat aacagcattg gcttcgtttt taaagatcgc
     6541 ttaaaacaac ccttcaaata gccaagataa cgctcagaag ttacttctga tagtaaatca
     6601 tctgttataa ataatatgtt gtgatggcct ttttgataaa ggtgttctac tgctgtttta
     6661 gccattagct gattatcatt atcaatataa gtggttttat tagtgtcacc ttgtggagca
     6721 cctacaatga caaatggtaa gttatttgtc atcaaatatt ttttgacagg atcatcttga
     6781 tcagaataaa gaataataaa accatcaact cgtttttgaa gatgcatcag tttcacttgc
     6841 tctatcaggt catcaagaga tatacctgta gcaatcgaca cagtaaaatg agattcttta
     6901 gcttcgttag taatagtcga caaaatttcc ataaagaaag gttcacttaa tctatcgcta
     6961 gttgtaatag gaggaaaaac aagtcctata ttgtgtgtca aaccgctcgc tagaatctgt
     7021 gctgcgacat ttggaacata tcccaaatct gccatcgctt ttctaacctt ctcttttgtc
     7081 ttcatagaaa tagatcgatt atcttttaat accctactca ccgtcgaagg gttaacacct
     7141 gccttttgag cgacatcttt tattgttacc atattaacct cgttactata tttaccaaag
     7201 ataaacctta tcatgggttt gtcatgtatt tcgtttccat tatacaatta tctttcaaaa
     7261 aatcaacttc aatcaagatt cccttgtcat tttaactcaa attctctaaa ctattttttt
     7321 aaaaaaacga ccttttttta aaaaaaggct tgactttttc tgcaagcggt tgcataatat
     7381 taagtgtaag aaatatatct taggaggaaa tagctatgaa atcatggcaa aaagttatcg
     7441 tcggcggagc aagtttgaca cttgcaagta ccttgttagt gggatgtgga tcaggttcaa
     7501 aagataaaaa ggaagctggc gctgactcaa agactattaa actttgggta ccgactggct
     7561 ctaaaaaatc atatgcagat accattgcaa aatttgaaaa agattctggt tacaccgtta
     7621 aagtggttga atcagaagat ccaaaagcac aagaaaaaat caaaaaagat gcctcaactg
     7681 ctgccgatgt cttttcactt cctcatgatc aacttggtca acttgtagaa tctggtacta
     7741 ttcaagaagt tccagaaaag tacaataaag aaattgctgc tacttctact gatcaggcgc
     7801 ttatcggtgc acagtacaaa gggaaaacat atgctttccc atttggtatt gaatcacaag
     7861 ttcttttcta caataaatca aaattagctg ctgaagacgt tacttcatat gatacaatta
     7921 ctacaaaagc aacttttggt ggtaccttta aacaagctaa cacttacgct actggtccat
     7981 tattcatgtc agttggtaac actttatttg gggaaaacgg tgaagatgta aaaggtacta
     8041 actggggcaa tgaaaaaggc gctgctgttc ttaaatggat cgcagaccaa gcttcaaata
     8101 aaggttttgt tagcttagat gctaacaacg ttatgtctaa atttggtgac ggttcagtag
     8161 cttcctttga atcaggaccg tgggactatg aagctgctca aaaagctatc ggtaaagaaa
     8221 accttggtgt tgctatttat ccaaaagtaa ctattggagg cgaaacggtt caacaaaaag
     8281 cattcttggg tgtaaaactt tacgcagtca accaagcacc agctaaaggt gatacaaaac
     8341 gtatcgcagc tagctacaaa ttggcatcct acttgactaa tgctgaaagc caagaaaacc
     8401 aattcaagac tcgtaacatt gtcccagcca acaaagaagt tcaatcttca gaagctgttc
     8461 aatcaaacga acttgctaaa accgttatca ctatgggttc ttcttcagac tacactgtcg
     8521 taatgccaaa acttagccaa atgggcacat tctggactga aagtgctgct attcttagtg
     8581 atgccttcaa cggtaaaatc aaagaaagcg actaccttac taagttgcaa caattcgaca
     8641 aagatatcgc tgcaacaaaa taatatgatc tcatgtcatc actgctatac taaaacaagc
     8701 acaaggtaag tacttctaaa aagttctttc cacttacctt atgaagagtg gaactaggct
     8761 ccatcacatt ttattcaagc ttagtctcac tcttacttgt ttttgtttta ctagtagctt
     8821 agtgctactt aaatttttaa ctctttaaaa gtttacgtaa cacttagcta tttcatccta
     8881 acaagagatt gaatctgaac taccactcta gtatcctaaa ataaaggaga atctatatga
     8941 ctcagtcaaa cttgacacca aatatatctg taatagaagc cttaaaaaga ggcagttggg
     9001 atattaaact ttcgagtatt atcatgggat ttgccaactt tgctaacaaa cagtttatca
     9061 aaggaatctt atttttaata agtgaactta tctttctagt agcttttgtc tcccaaatca
     9121 tccctgctat ccgtggcctt gtcactcttg gtactcaaac tcagggaatg actacaaaaa
     9181 ctattgatgg gattaacatc caagttgctg ttgatggcga taactctatg ctaatgctta
     9241 tttttggttt agcatcactc attttctgcc tagtctttgc ttacatttac tggtgtaatc
     9301 tcaaaagtgc tcgtaacctt tatcttttca aacaaaaagg tcagaagata ccaagcttca
     9361 aagaagatct tgccacactt acaaacggtc gctttcatat gaccttaatg gctatcccac
     9421 tgattggtgt gcttttattc accattcttc ctttgattta catgatctgt ttggccttta
     9481 ccaattttga tcataatcac ttgcctccaa aatctttatt tgattgggtg ggacttgcta
     9541 actttggaaa tgttttaagc ggccgtatgg caggaacctt ttttcctatc ttctcatgga
     9601 ctttgatttg ggctgttttt gccacagtaa ctaatttctt ctttggtatt attcttgctt
     9661 tgttaatcaa taccaaagga ttaaagtgga aaaaaatgtg gcgaaccatc tttgttatca
     9721 ccattgcagt tccacaattc atctcattat tgattatgcg gaacttactc aatgacgaag
     9781 gcccactaaa tgctcttctc aataaaatcg acttgattaa tggctcactg ccatttttat
     9841 ccgatcctct ttgggcaaaa ttctcaatca tttttgtcaa catgtggatc ggtattccat
     9901 ttaccatgtt gattgcgact ggtattatca tgaaccttcc aagtgaacaa attgaggctg
     9961 ctgaaattga tggcgctagc aaattccaag tcttcaagtc tatcacgttc cctcaaattc
    10021 tcttgatcat gacaccaaac ttgattcaac aatttatcgg aaatatcaat aactttaacg
    10081 tcatttacct ccttactggt ggtggtccaa caaattcaga atactatcag gcaggaacaa
    10141 cagacttgct ggtcacttgg ctctataaat taaccgtcac agctgctgac tacaatttag
    10201 cttctgttat cggtatctta atctttacag tttcagctat ctttagctta cttgcttata
    10261 caaggacagc atcctacaag gaaggagcgg ctaaataatg aaaaacaaac gtcgatttca
    10321 acttggactt gtttatgcta ctttaatcat cctctcaatc atttggctct tcccaatcgc
    10381 ttgggttatt cttactagct tccgtagcga aggaactgct tacgtcaatt attttattcc
    10441 taagactttt acattaaatc actacattaa tctttttact aatgaaacct ttccttttgg
    10501 aaaatggttt atgaatactc ttattgtagc cacttttaca tgtattattt caaccttcat
    10561 aactgttgcc atagcctact ctcttagccg aattaagttt aagtttcgca atggcttttt
    10621 aaaactagcc cttattttaa atatgttccc tggtttcatg agcatgattg ccatctacta
    10681 tatcttaaag gccttaggtt tgacgcaaac cctaacagca cttgtccttg tttattcctc
    10741 aggtgcagcc cttggttttt acattgcaaa aggatttttt gataccattc cttattcact
    10801 tgatgaatca gctatgattg atggcgctac tcgtatggat attttcttta aaataaccct
    10861 tcctttagca aaaccaatca ttgtctatac tgcccttctt gcttttatgg ggccttggat
    10921 tgactttatc tttgcacaag ttattttagg tgatgctaca agtaaatata ccgttgctat
    10981 tggactattt tcaatgcttc agccagatac cattaacaac tggtttatgg ccttcactgc
    11041 tggttctgtc ttaatcgccg tcccaatcac tctcctcttc atgtttatgc aaaaatacta
    11101 tgttgaaggc atcacaggtg gttctgttaa ataagttaca acataccaaa ccttctaagg
    11161 gcaagccctt taggaggtgt ttgataaata aggccgtaga taatcatatt agtcctcaca
    11221 tttatcttca gatcccgcgt tgtaaaatga agtgcaacaa aaaagacatg ttcgtctgat
    11281 atactagaat tccccaattc agtatggaaa gcagatgaat atgtctaata ttaattctac
    11341 cagaaaatcc tcctattctc atctttcagc cacagaacgg ggtgaaattg ctgcttatct
    11401 taaaatggga aagaaacccg ttgagattgc tcgacttctg ggccgtcacc gttctacaat
    11461 ctgccgagaa ataaaacgtg gttcagtaga tcaggtaaag gataagaatg gaaaacaaac
    11521 cttcttcaac gcctatttcg ctgatagtgg acaacgtgtc tatgaaacca atcgatttgc
    11581 ctaagatggt tagtattaga aaacgttcta agaaagtcat gaaaacgaat aagaagactt
    11641 taggtaaatc tatcgaagaa cgtccagaat atattaatga tcgttctgaa tttggacatt
    11701 gggagattga tttggttctc ggcaagaaaa ccaaaggtga agctgttatg ttgactttgg
    11761 tagagcgcca gacacgctat gcactaggag ttaagctaga agacaagcag tcccaaacca
    11821 ttaaccgtgc tgtcacgcat ctcatcagtc attatcctat tgcatccatc acagcggata
    11881 atggttctga gtttagttta ctctcagact taaaagctgt tgacgtttac tttgcacatc
    11941 cctattcttc acatgagaga ggaacaaacg agaacttcaa tggcctcctc agagaatatg
    12001 tccctaaagg aatctcactt aatccactaa cctctgaaga acttgacaat gatattactg
    12061 ccatcaatga gcgcctaaga cgacttcttc aatagcaatc ctcaaaattc ctgtttgagc
    12121 tatcccgaac agcttaacct ctggaactct agttatctat gaactcgttg cacttgactt
    12181 gacaacttgc gagagcatat cagtaatttt tctgctaatt gaaaacaggg tatttactgt
    12241 cacacaagtc tgtcctttct ttttttctac aactttattt cgtcagcgta aataaaacaa
    12301 aagctctata atctcttgaa tgggtaaatc cactgtagag attatagagc tttttgaata
    12361 tcaaaaaagt cccataagat ttataatgaa aagcaaccaa actctcatta gaaagactct
    12421 tatggaacat atcaatcata ccttacaaca catcggaatt aaagacaaaa atatcactct
    12481 aaacaatgtt ttgaaggatg aatctcctac tgagctcgtt actacttatc agaaaggtag
    12541 ataggaaatc ctgatgaaga gtgtgtccaa gggattatca attaggtctt agattacaaa
    12601 atagtaattc aggtatgctc tactgttttc aacactagtt ctgcaatttg ttttcgagct
    12661 tgcttagctt ctcttattgg aaaaataaca tacgcatgaa tcattttttc tgcaataatc
    12721 agctgattag caattcgttg tcttgttaat tgatcatgta aagacataat gtctgggtaa
    12781 aaaatctctt ttgtcccaac aaaggtcgtt atttcaggca aatcctcata atcaccatac
    12841 aaaggactga cataaggaag ttgcatatta ccttgaccac ctgcccatag ttcacctata
    12901 tcacgaagac gacgagcatc taggtaagct tcttctgctt caaaatcctt gtaggcttga
    12961 tttttaaaac taacatctaa ccaaggagat ataagaatta attgctttgg ctgtggtgct
    13021 gttttagtat ctcgtatata cttagcaaac gccaaagcca tacccccacc agaagaatca
    13081 ccaatgacac taacttgact cggtccatta gacaagcaaa attgctggta agcttcaact
    13141 aatttaggat agacatcttg ataagtagca tacggtactt taggaaagtt aggaaaaaca
    13201 accttggcat tagtcagctg tataagatgc ttaaccgtct taaaatgaag tttttcgggt
    13261 cgtcgtaaat agacactgcc ataaagataa taaataacag gctgatgact ttgcttttga
    13321 tcattaataa taaaaacttg catcccgttc acatcgtatt cttgagttga aaaacctact
    13381 atctcttcag gattatctag atgataaggg atattacgat tacgctgcgt ctcaaccccc
    13441 ttataattat caactttttt agataactta tactttctat aagcaaacat tttctcaacc
    13501 aaccaacttg aaaaggagcg cttttgacca tattcaacta tcaaaatacc tagtatcact
    13561 ccaaaaaaaa tcaccacagc aataatgacc acttattatc ctcgttttct aatattattt
    13621 tactattgca agtctttcct atttgcccaa attttactat aaaaataagg gttcatttta
    13681 tagttgggta ctggctgctt cgtttctaga aatggttgca ctttcttatc aaaagctaac
    13741 cagccattcc aaccgagatg gatggtatct tgcataaagt aggactcacc accatctttt
    13801 gagaagtcag caatgcgatg aaatccttgt gactttaact ggaattttat tttacgaact
    13861 gccgcttgat acttatcttg atttaagccg gtataatccg cccaagcttt attaacagga
    13921 gttataacaa agagtacatc tgtttttcgt ttagcaaatt ctgataacaa aagctgaaaa
    13981 tcattgtatt ctggtgacgc caggtaacta taattaactt ggaaattctt ataaagattg
    14041 tatttaggtg ctattcgttt acgataaaat gtatttttaa tcccaaaacg gttgttggtt
    14101 gttgctaatt ggcctctctt agttgctaat gcattcaatt gtttatacga aaatacttta
    14161 ggtaatccct taacgcgagg caaaattctt ttttcatagt tagtagattt gcctaaaaaa
    14221 ctaaaaaggg actcttctct caatgctact tgatgttgac atttcaaaat agctctgtct
    14281 aaccgactaa gagacttacc cttacttact tttttcaata agtttgattt agacacacca
    14341 gggttaagct caagcaaacg ctttgctgca aactgtgatt ctttatcagt tctagctttt
    14401 agtaaaaatt caatcacttg agtgttagac aagtacatct gaaccgcact aggattaatc
    14461 ccttgagcag taaaccattg aggagatact acaaagatgg cttttttctt ttgcatttca
    14521 ttggtaattt gttgcatacc ataataatgc gacaaagatg ctgatcctct cttaccaatt
    14581 aaaaatggtc tatagctccg cttgtagcgc tctgcaagca ccgaagggtg catactatcc
    14641 attcgactcc attcgctaga accaaaaaaa ggcacaaaac gacaagtctc atctgataaa
    14701 gcttgtcttt taatcaaacc atttttaaaa gaactatctg tgatcgcaac ggcatttgct
    14761 ttttcctgag ctatggaatg atcaagttgt gtgggaaaac taaaaatagt aatcactact
    14821 aaaacaaagg caataagaag aggacctaga attaaccaga gtctcttaag catgttgcaa
    14881 ttcctctaca ccttgaacaa tcttagttac tgtgttccaa tcatcacgac caaattctga
    14941 aataggtact ttaatattga acgttgactc taactcaaca atcaattcga ctgtcccaag
    15001 actatccaac acacctgcat caaacaagtc ttcgtccatc atctctgaaa catcttccat
    15061 aaacaaacgg tcaaataatt caattacagt ttcttcaata gacattttta tacttccttt
    15121 tattaatgta gtggtctgtt aaaccaaagg tcatttaaaa aaccagagaa taacagaagt
    15181 gaaaacatga caacgtggaa agttaccacg atacataaga catggaatgc cctgctttga
    15241 aagaggggtg ataagccttt tttcttacgg tgacggttga tttctttttt cttacgaatc
    15301 caagcatcat taataataag tcctatacca tggaaaagcc cataagcgat ataataccag
    15361 gttaagccat gccaaaatcc catgactagc atattaacca gataggcaac acctgaagtg
    15421 acatttcggt ttttaaaggt tttatgctta atcaatagat gaaccaatcg cataaacaca
    15481 taatctctaa accagaagga caaactcatg tgccatctat tccaaaaatc tttcaaactt
    15541 gcagataaga aaggcaggtt aaagttttct ggtgttcgaa tacccaatag gtaggaaata
    15601 ccaatcgcaa acatcgaata accagcaaag tcaaaaaaga gattcaagcc atacacgtac
    15661 ataaccagaa tagtttcctt attaaagtag ccaccaacca tcaaagcctt attttcaagg
    15721 agaggaagta agatgccacc caaacaatag gaaatgatat gcttgtatag gaaacctaac
    15781 atgagataca tgactgcctt attgagcatt gcaaaataat catcacgttc aggaagttta
    15841 tgataatctt cctgaaaacg tctgaagcga tcaatggggc cacttgagaa agtggggaag
    15901 aaaatcatga agcgaataaa atccggtaaa cgaacctctt ggagagtccc gtcacgcatc
    15961 tcaataatca ttccaatact tttaaaggtc aaatatgaaa ttcctagaaa actaaagagt
    16021 gtttgagaag aaggacctgt taggggagca actttgaccc agataagggg gaataaggcc
    16081 atcgcaatag ctaagtaaaa cactcctgca ctattagctt tctcacggta tttctggtaa
    16141 gcaaaaacac tgatgatttg ccacaaaaga taaaagagaa aagcaactaa ttgttgataa
    16201 tgatctcctc caaacataaa gagaataaat accaaactca ccaaggtttc ataagtgctt
    16261 aagcgctttt gtttaaaaat cccaatgatg actggtaaga aagccaaaat aagatagaca
    16321 aagtaaatgg ggttaccgta aggttccatg tagggaatgt ggctaaaaaa catcatcatc
    16381 ggttattgac ctcattaatc aaagttttaa tatctatctt accatttgga gttaatggta
    16441 gactatctcg ataaagaaac ttagaaggca tcatataact catcatatga tccttaacag
    16501 aggctttgat agctttggtt aactccaatt ccctatcaaa acgctcttta accccatctt
    16561 tgacaacgat ataggccaag agattttgaa ccttatgttc tttattgtac cttggaacag
    16621 ccacagccga tgctaccatt ggtgattgat tcaactgttg ggaaacatct tctagttcaa
    16681 tacgataacc agcatattta atctgaaaat ccaaacgccc accatacagc aaaatattat
    16741 cttctgtcaa tgagccaatg tcccctgtat gataagcagg ctgtccttta aaagtaaaga
    16801 aagcttctgc ggttttctca ggattgttga ggtaaccttt tgacacagca ggccctgtaa
    16861 caataatttc accctgctcc cctgaagata actccttacc atcttcatca ataatatagg
    16921 tcggagaatc tggtttgggg tagccaatcg gcaagcgggt ataattatcc accatttctc
    16981 tagtaatttc aatagcggat aaggctacag tcgcttctgt tggtccatag gcattgataa
    17041 tcttggcact cgggaaacgt tcaaagagtt ttcgagccgt agaaacggtt aattcttcgc
    17101 catcaaaata aaaatgcgtt aaagctggca tcttagcctg gcaaaaatca tcgctaagca
    17161 tggccatatc agcaaatgaa ggagtcgatg tccaaatgcc aactggaagt tgcgcaatcg
    17221 ttgtaaataa ctgtttaaag tctgccacca attcttttgg aagtgcaaat aaggttccac
    17281 ctaaagccaa ggtaggtgcc cagtacatga cagaaaggtc aaaggaatag ggtggctgcg
    17341 ccagcatttg tggctgttta ggtacatcaa atgctgcatc ttcgatcatc cagttggtaa
    17401 agctcaaaag attgtcatgt gaaatttgca ccccttttgg ttggcccgtt gttccagagg
    17461 tgaaaataat gtaataatta tcatctcctt taacagaatg tgttcgctca tagggcattt
    17521 ctgctaattt tgctgactca atctctgata gtgagacaag ggaaatccct tcaatagtaa
    17581 gagggaattc ctcaatagca atgattaaac tgggctttgc aatctcaata atcgctaaaa
    17641 tacgttctgg tgctgaatgc acatctactg ggatataggc atgaccagat ttggttaaag
    17701 ctacaaaagt agctaacata tcataagttt gcgccccaaa aaccaaaact ggagattttg
    17761 ccagtaaagc taagctatct ataaatgcag caatgctatc agaatctctt ttgagttgtc
    17821 cgtaagtgcg gcgttcccct aaacaatcat aaactggaaa atcagcctgt gtctgagcaa
    17881 actgctcaat actgtcaatc atatccttaa tcatcagtca atctcctaaa attcattata
    17941 aataaagtta ctttgaccat gtcctagata accaaagaaa tagaccagca acattaaaat
    18001 cagataaaat aaaattgtct tgccaataaa aacagcaatt cctctcattc ttgatttgtt
    18061 ttttatcata ctttaccttc ttgtattagt gaaataatgt cctaaaaaat tctactcgaa
    18121 aaaacctaac ttgacaagct aaaagtcata ttattaaaaa gaaaattttt ttaaagctta
    18181 actatttaga cagttaaatt ttatgccttt ttactaaact tactaagtta atctttactt
    18241 taaaaagtta acttaaaatt gtcctaataa aaagaattat ttgactttaa cttatatatg
    18301 ttaataagta taatataagc tttattcaaa acctagtcca ttaatttaag ttctaaaatc
    18361 aagtctcgca tttgagctgc caattcgaaa tcaagtaatt cagctgcctc ttgcatttgt
    18421 ttttgcagag cattgatcgc ttcttttcgt tctcctcttg acatactttc ataatccatc
    18481 tcttcttttg atatatcatt gtggcttgtt ttacttatac taataaggcc tctgatgtct
    18541 ttttttatag tttgtggaac gatgccgtgc gctttgttat atgctatttg aatctcacga
    18601 cgacgagccg tttcgtcaat agcccgctgc atagaatctg tcatcttgtc cgcatacata
    18661 atgacatgac catctacgtt tcgagctgct ctaccgatgg tctgaatcaa gccgcgttca
    18721 ttacggagga aaccctcttt atcagcatcc aaaatggcta caagactaac ttctggcaca
    18781 tcaatccctt cacggagcag attgattcca atcaagacat caaaaacacc aagtcgtaaa
    18841 tcacgaataa tttctgtccg ctctaaggtt ttaatatcac tgtgcatata cttgaccttg
    18901 acacccatct cttttagata atcagtcaaa tcttctgcca tttttttagt taaggttgtg
    18961 atgaacgtcc gttcatcgcg cgctacgcgc tggttaattt ctcccaacaa atcatccatt
    19021 tgccccatac ttggccttac atcaatttca ggatcaagta gcccagtcgg acgaataatt
    19081 tgctcaataa ttgtattagt ctgtgacatt tcgtattcac caggcgttgc tgaaacatag
    19141 acaatttggt gcacatgact ttcaaattcc tcgcgtctta agggacgatt atcaagagct
    19201 gatggcaatc gaaaaccata gtcaactagc atttgttttc tggcttggtc accattatac
    19261 atgcctttga tttgtcccat tgtcatgtga ctttcatcaa tcataattaa aaaatcttct
    19321 gggaagaaat ctaacaaggt ataaggaggt tctcctggtg acctgccatc catatgacgg
    19381 gaatagtttt cgactccgct agtatagccc atttcacgta acatttcaat atcatattcc
    19441 gttctttggc gtaatcgctg tgcttctagt agtttacctt cagattcaaa taactgtaac
    19501 tgctctgcta actctgcttg aattttggct attgattgct ccatatgctc atcatttgtt
    19561 acaaagtgag tagctggaaa taaaaccaaa tggtcaactt ctccaatagt tttcccagtt
    19621 aaactttcga tttcacatat acggtcaatc tcatccccga aaaattccac ccgaaaagca
    19681 tgttcatccc tggatgctgg aaagacctca acaacatcgc cacgtacacg aaaacagccg
    19741 cgttgaaaat caatatcatt acgctcaaat tgaatatcta ctaattgatt tagcaaagtg
    19801 tcacgtgata tctcctgacc tggacgtagg ctgactgctg aatctgcgta ctcttttggc
    19861 gaacctagtc cataaataca agatacagaa gctaccacta tgacatcgtt acgctcaagt
    19921 aaagaagagg tggctgaatg gcgaagttta tcgatttcat cattgactga actatctttt
    19981 tcgatatagg tgtcgcttga tgggacatat gcttcaggtt ggtagtaatc ataataagaa
    20041 acaaaatatt ccacagcatt gtctggaaaa aattctttaa attcaccata taattgtcct
    20101 gctaaggttt tattgtgagc tatcactaag gtaggtttat ttactttact aattacttgg
    20161 ctcatggtgt atgtttttcc cgttcctgta gcacctagga gaatctgagc tttttctccg
    20221 ccctcgatat tatcaactag gctttcaata gcttgtggct gatcaccaga cggtttatac
    20281 tttgatttta gtttaaatgg tttatcatca cgtttatcaa tcattttata ccctctaata
    20341 gtcttactct cttatagact attttaacat agataagcca gaatcacctc caataagcgt
    20401 aaaaaacatg tcatttacat gttatgtttt atgacatata aataacaaat ttcttgctta
    20461 atgttcaata ttttgttata attaaccata ttttttagtt ttataaggag attagtatga
    20521 cgcacaaaat aaaagtattg ctgcttgcga taatgtctat ttttttgaca tgcaatattg
    20581 caagtgctga aactattgct attgtttcag atacagctta tgccccattt gaatttaaag
    20641 actcagatca aatttacaaa ggaattgacg ttgatattat taatgaagta gccaaacgtc
    20701 aatcttggga tttcagtatg agtttcccgg gttttgatgc agctgtaaat gctgttcaat
    20761 ctggtcaagc gagtgctcta atggccggta caaccattac gaatgctcgt aagaaagtct
    20821 ttcatttctc agagccatat tacgatacca aaattgtcat tgcgacacgt aaagccaatg
    20881 ccatcaaaaa atacagtgac ttaaaaggaa aaacggtcgg tgttaaaaat ggaacagcgg
    20941 ctcaagcctt tttgaataac tataaaaaaa agtatgatta tactgttaaa acatttgaca
    21001 caggtgatct tatgtataat agtttatctg ctggttctat tgccgctgtt atggatgatg
    21061 aggcggttat ccaatacgca atcagccaaa accaagatat tgctattaac atgaaaggag
    21121 agcccattgg aagctttggg tttgctgtca aaaagggaag cggatatgat tatctagtta
    21181 atgatttcaa tacagctctt aaagctatga aagctgatgg tacctaccaa gctatcatga
    21241 ccaagtggtt aggcacagat gataaagcta ccaccagtca ggcaacggga aatccatctg
    21301 ccaaagctac acctataaag gacagttata aaattgtctc tgattcgtct tttgcacctt
    21361 ttgaatttca aaatggtaag ggcaaatacg ttggtattga catagaatta atcaaagcta
    21421 ttgctaaaca acaaggtttc aaaattgaaa tcgctaatcc aggtttcgat gctgccttaa
    21481 atgctgtgca atctagccaa gcagatgggg tcattgctgg tgcaactatt actgacgctc
    21541 gtaaagctat ctttgatttt tctgatcctt attatacttc taatatcatt ttagctgtta
    21601 aagctggaaa aaacatcaag aactatgaag acttagacag aaaaacagtc ggtgctaaaa
    21661 acggcacttc atcttactct tggttaaaag aaaacgctcc taaatatggt tataatgtca
    21721 aggcatttga tgatggttct agcatgtatg atagcttaaa ttcaggttct gtagatgcta
    21781 tcatggatga tgaggcggtt cttaaatacg ctatctctca aggtcgtcgc tttgaaacac
    21841 ctcttgaggg catttctact ggtgaagttg gttttgctgt caagaaagga actaatccag
    21901 aattaatcga aatgttcaac aatggcttag ctgctctcaa aaaatctggt cagtatgatg
    21961 acattataga taaatacctt gactctaaga aagctgcaac tccttctgaa aaaggtgctg
    22021 atgagtctac tatttcaggc ctattatcaa ataactacaa acaactattg gcaggacttg
    22081 gaaccacgct cagtttaacc cttatttcat ttgctattgc tataattatc gggatcatct
    22141 ttgggatgat ggccgtgtca ccaactaaat cacttcgact catttcaacg gtctttgtgg
    22201 acgttgttcg agggattcct ttgatgattg tggctgcctt cattttctgg ggagtaccaa
    22261 accttatcga gagtatgacc ggccaccagt caccgattaa tgatttctta gctgctacaa
    22321 ttgcactgtc acttaatggc ggagcctata ttgctgaaat tgttcgcggt ggtatcgaag
    22381 ctgttccagc agggcaaatg gaagctagtc gaagtcttgg tttgtcttac ggaaccacga
    22441 tgagaaaagt aattctccca caagctgtga aactaatgtt acctaacttt atcaatcagt
    22501 ttgttatttc attgaaggat acaacaatcg tctcagcaat tggtttagtg gaactcttcc
    22561 aaacaggtaa aatcattatt gctagaaatt accagtcgtt ccgcatgtat gctattttag
    22621 caattattta ccttatcatg attacactct taacaagact tgcaaaacgt ttagaaaaga
    22681 ggcttaacta atgacagaat taaaaattga tgttcaaggt ttacacaaat cttatggtca
    22741 aaatgaagtc ttaaaaggaa ttgatgccaa attctacgaa ggtgatgtcg tttgtatcat
    22801 tggtccttct ggttctggga aatcaacctt tctacgtacc ctcaaccttc tagagacgat
    22861 taccagtggg aaggtcatgg tggacggttt tgaattatca gatcctaaga ctaatattga
    22921 caaggcacgt gaaaatatcg ggatggtatt ccaacacttc aaccttttcc ctcacatgac
    22981 tgttcttgag aatattatct ttgctcctgt tgaattaggt aaagagtcta aagaagttgc
    23041 taaaaagcat ggcatggcac ttctagaaaa agtcggactt tctgataagg ccgacgcctt
    23101 cccaggaagt ttatccggcg ggcaaaaaca gcgtgtcgcc atcgccagaa gtttagcaat
    23161 gaacccagat attatgctct ttgatgaacc aacttctgct cttgaccccg aaatggttgg
    23221 ggacgttttg aacgttatga aagacttggc agaacaaggc atgaccatgt taattgttac
    23281 tcacgaaatg ggatttgctc gccaagtagc taaccgtgtt atctttacag acggtggtca
    23341 attcttggag gatggtactc ctgaagagat ttttgatcat cctaagcacc ctcgtctcat
    23401 tgaattttta gacaaggtct taaacgtcta atagagcaga caccatacta acttccaaaa
    23461 aataataagg caaggaaaca ggtttccttg cctcagactg aagacaaagt ccttagaatc
    23521 acttttctag gggcttttca tgatacttag gagtataata taagaaaaag gacttgtgag
    23581 gttctcctat gttacacaaa gaaaaacctg actataaccg caatcagtac ggtttctata
    23641 cccttgacca gatagtgcct gatgaacatt tcctgcgcca agtggaagct gtgattgact
    23701 tcgacttcat ctatgaccta gtagaagaca cctattcgtc tgataatggt cgccctagcc
    23761 ttgatcctgt catgttggtt aaaatccctc tgattcagtg cttttatggc attcgttcca
    23821 tgcgtcagac catcaaggat attgaagtga atactgccta tcgctggttt ttaggtttga
    23881 ctttggataa caaggtgcca catttcacaa cctatggcaa aaattattcc cgtcgctttc
    23941 aagaaaaagg cttgattgag tctattttta cgcatattct tgggctatgt atcaatacag
    24001 gcctgattga cccgatggag attttcatag atgggactca tattaaggct gcggctaata
    24061 atcgcaagtt catcaaccga gaggtggaaa aacaagccaa gttcatgagt gaacagctag
    24121 aaatcgaaat caatcgggat agggagaagc atgggaaaaa gccgctaggg cccgtcgcta
    24181 aaaaaatctc cacaaccgat ccagaaagtg gctggtttca caaaggtgat cataaggaag
    24241 tcttcgctta ttctgctcag gtggcttgtg acaagtatgg atgggcgctt gcttatagtg
    24301 ttgaggctgg aaatatccat gatagtcagg cttttcctgc actttttgcc aagcttgaac
    24361 ccttgaaacc acagtttatt attgcggatt ccggctataa cattcccagc attgccaagt
    24421 ttctgattga taaggagatc actcctgtcc ttccttacac acggccaaga ggaaagaaag
    24481 accttctacg tccgaaagaa tttatttatg atgagcactt tgaatgtgtc atctgccctg
    24541 aacatcaagc cttgacctac cgcactacga ccagagaagg ctaccgagaa tacaaaagtg
    24601 accctgcaat ttgtgccaat tgtcccctgt tatctgtatg tacgaccagt aagaaccgcc
    24661 aaaaagttgt cacacggcat atttggaaag actatttgga acagtgcgag gacattcgtc
    24721 atcaaagggg gatgaaggag ctctaccagc atcggaaaga gacgattgaa cgactgtttg
    24781 gcacagccaa ggaataccac aatctccgct atacgagaga gaaaggcaag tccaaaatgg
    24841 aagataaggt tggactgact ttggcatgct taaatctcaa aaaacgggtc aaaaggatgg
    24901 tgggagagcc tttttatttt gttcagatga ggtggtttaa gcacggaaac agacattttt
    24961 atctaaaaac actaaaaaag acaaacacca aatcgatgtt tgtcttcaat ctgaggcaag
    25021 gaaacaggtt tccttgcctt ttttggttac tgttattatt caaaccagca aaatagggat
    25081 actcttatga ctctctcctt cataagagtg tcccctatgc ttttttatgg gcgtttatgt
    25141 ttagtgaggt aataacctaa tcccgtaaga gctagtcccg tcactatgtg tgagtatttg
    25201 ttaccaacca tcggactaat ggcaatgaga aaaaagccaa cagccattaa aaaagttgct
    25261 ccattttttt ctgtcatgca aggtcactcg ctttttcttt attggccaaa atgacaaatg
    25321 gtgcccagat aaggaaggca acaaagaggt taaacagtga aaccaaacct gccataatat
    25381 tacctccagt agctaggtaa gcataaagtc caacaggggt aatccaaggt actgataaga
    25441 ataccggtgg aatcaaacct attgcagtag caaaataagc tatgctagca caaattggtg
    25501 gcacaattag ccatggaatc acaaaggttg gattcaaaac aattggcatc ccaaatgtaa
    25561 ttggttcgtt gatattgaaa acacccattg gtgcggacaa tttggcaatg gttttatgct
    25621 cttctcgttt tgagaatatg aagatagcaa taatcaatgc caaggttact cctgaaccac
    25681 ccatttgagc ataagcatca aaggacccgc gtgtccaaag gtatggtaaa ttagcagcgc
    25741 tatgcgctgt attgtaagca gctgtatttt ctgttaaagc taccatataa ataccatcca
    25801 tcactggggc taagacatta tgaccatgca agccgaagaa ccagagcagt tgaactaaga
    25861 aggttaacaa gataactgaa ccaataccct gtgataagcc tagtaatggt aattggatat
    25921 aggttgaaat gacatcactt agggaagaac ctgttaatgc aaagatgagg taggcgaaaa
    25981 ttgccgaagc gtaaatcgca actgttcctg gaataatggc agcaaaggct ttattaaccg
    26041 caggtggtac attatctggt aaggtaatgg taatattacg tttggtcaaa gccgcataca
    26101 caaaacttga taaaaagcca ataattaaag ctgtgaacaa gcctgtagca ccgacatact
    26161 ttagagctat tgctccccat tgactagttt caatacttga acctccaccc gcagtaacga
    26221 ctgaaagccc catttctttt aaattgctaa ttaggttagc agaggcattt tcaagtggtg
    26281 tcgaaatggt taaagtctga ggtagggtgg caataaatga gccaaaagaa atcaatcctc
    26341 ctgccaatgg attaatctta tgcataacag ctaaattgta accgaaagca aaggcaaaaa
    26401 agagcgccat gataccaatt gtcccaaaat aaacatagcc attgatgtcg ataacaggtt
    26461 gcatagcttt tgcaaaccct gtccatccca tattgtttgg aatatcgcgt aaaaaaacgt
    26521 tcaataagac agcaactgaa cctgccatgg taataggcat cattgaaata aaggaatcac
    26581 gaatagctac taaatgccgt tgtgacccaa tttttcctga aatatccata aacttatcag
    26641 aaaaatgcga cataaatctt ctcctctttt tattttttta atgtaacaaa ggtaacctta
    26701 aaagcagcgg tgtctgccta acacaattat ctcaaaatca tccttgttaa acgtgatgct
    26761 tagagataac cggtaatcga ctcttatcca aatgaaccct tctctctcat ccaaggtctg
    26821 tgaataatct tcacaaagac gatggttgct gcaactgttt agcatattgg ataagggctg
    26881 ctaactgagc ttgagattgg cgttctaggc tttttttgaa cagtttgcca acaataaaat
    26941 gatttgcttt ttgaaaaata tctagaggat gatagtcata agaataggta attctagtcc
    27001 gattctcccc cagagcctct aatcgataag ccaattcctt tatcccatga ttggaactaa
    27061 aacaagcagt atataattgc ggagcttcta gggccgtaat aagcaccctc actgtacgct
    27121 ctttgtattt actataatgt ttaacatagt ttatccccgc tttgatatca tctcttgaca
    27181 actgtctcaa ggtattttgt cgatgatctt cttggagcga tatcagcatg gcttcaaaac
    27241 aatgatgaac ggaaacatct ccttctgctg aaatgatcat gactcacccc tctgtattgc
    27301 tgacattttg tcgtaaacgg taaccaattc cttggctaaa tcaataaagg ctaaggcagt
    27361 catcatgtga tcttgcccat gcaccatcaa taaagacaat tcaatcgcat caccagctgc
    27421 ttcttgggag agcaaatgtg tctgcgattt atgggcaata tttaacgagt ttgtcgcttc
    27481 ttgaagtaag tgctgagcct cctcaaactg cccatctcgt gctgcatgaa tagcctctac
    27541 ggccttgccc ttggcttcgc ctccatacat gattaagccc ataatagctt ctaagttgga
    27601 tggttccgtc atgcctactc ctccatcatc gctagggctg tttcaaggac tttttcaccg
    27661 ttcataagac cataatcagc catgttaatg gcatctactt taatatctgg ttcaaactta
    27721 tctttaaaat cctttagtaa gaatttgact tgtggaccta acaagagaac gtcaatgcta
    27781 ttagcagcca cttcgttgtc agcttcactc acaggaactg cccaaataga aacttcaagg
    27841 tcacgcgctt gggctgcttt ttgcatctta gtcaccaaca tactagttga cataccggca
    27901 ttacaaacta acataataga tttcataagg tttctccttt taatcgtttt aatcatgaat
    27961 aagtggggta aacactgtca tgaatttgga ataatttggt tcttctagta acgcttgctg
    28021 aagctccacc tgattgacaa aagatgccaa acctggtgat acatatttta acctatgatt
    28081 atgcccttta gacggggata atagaaagac aaaatgaaca gcttgatgcg ccttgtccca
    28141 ctcaagaggc tctcggcaaa tagccactac tacctgttca gaataagtca tgggattagc
    28201 aggatgcgga aaggcaagca cttctccata gatgactggg ctgtaatttt ccctcagtac
    28261 catttgatga tagaagtcct ctacaaacgt ttctgttccc gcctcgtcaa gacaagcaat
    28321 catccgtaaa agcaagtctt cctttgagat tttctcgtct aaataaagaa aacgattagg
    28381 gctaaaaaca cctgttagaa gctgctctgc ttttgctaaa ctcatctgtg acggtaaact
    28441 gacctctttc ttgatacctt cttgttctcc aataaattgt cgaatagttt caatatcctg
    28501 atttgacaaa aaaacactga cagtaatcac tggtgttaaa aacatcagat tggcaaggct
    28561 gatagaggaa ataatcaaat caacggtttt cagtcgctct tcggttattt catagtaact
    28621 gataacatcg acaatacgca aacgtccttc aaattccttt tccaagcgat ttttcaacat
    28681 catggcacta ccataacctg tggcacaaac tactagaacc ctcaatttat aacggtttga
    28741 ataacgctca atggccgcca ttaaatgcaa actaatataa gcccattcat catctgagac
    28801 atcattcttt tgacatacaa gcaaatccga aaaggtctgc ttggtaaggg taaatatttc
    28861 aggatactgg cttttaattt cctcagttaa aggattagtc agctgaatat ggttttcaag
    28921 acgtgtggtc aagggcatca tgtgggctaa taaaccttga aataaattgg tatctgtttc
    28981 taaagtcatg cctgtcaatt gactaatctt ggcaatacat gcttttaaat ggtcctgcaa
    29041 cttttcatcg gtattatcat cttgccaatg cttaccaaca gaatgtttga cctttagatg
    29101 cagtgcaata taattagcct cctctttagg aaaacgtatc cccatcactt cttccactcg
    29161 atacaaaatg cgcagagcta cttgatactc atcagactga cgaatagcta ttggaatgga
    29221 aaacagttct aatggacacc ccgatcgaat acgctgaacc attagggcaa tatgcaagac
    29281 tagattattc atgacaaaat cagaaagttt caacttagca tcccgacatt catccaagac
    29341 aataatcatg atttctgcaa aattaatacc ttcaagaaag gtattaccta ccatggtgga
    29401 caaggtatta tcaaaactag taacaaaaaa atagtccatg ataaaatgcc taatgtcctc
    29461 ttctttacct cttatttgaa tatgttggtg agttatttca agctctaact ggtaaggtat
    29521 tatgcgctcc ttaatgcctg ctaaaacatg ttttaaagtt gtccgactga tatacaattc
    29581 ttgacaaagc tcttcaaaat cctgaacggc atcttcaaaa aagaatttat gaagcacata
    29641 atcttctcga tcaaccgatt cttccacttg agtcacgtct gctaaacgtt ttttagacgt
    29701 cacactttct tgccaaaaga tgtcaaatgc catagaatgg tcaatttcta agcagtaacc
    29761 tcgaccttgt ttagaaatga tgtgagctcc gtgttcagga aggctactga tcagttcttt
    29821 gaggtatttc ctaaccgtac ggtcactcat accaataacc tcagccagag ttgcactaga
    29881 gacaaactgc tctttgtgat ggattagaaa tgttatgatg gccagttctt tttttgataa
    29941 cattagtcct ccttactact ttagaaaacg ctctctaccc tcttttagtg taccaaatat
    30001 ttcctgaaaa aggtgaccat cattttccgc attgattgtg aaaagaatct atgatgggtc
    30061 aatctccaaa caaaattcct gccaaggtcg caaatcatct aacaaactaa gatagtcctc
    30121 tctgacctca gcaaccacat tagcttttga actaaccgta aaatttttca aagtaatttg
    30181 cagttctccc ttatatcgat gatagcggtc attgtcaata ataatgctac ctcgtttgac
    30241 ctccttagat tggtctcttg gagcaatcga ttcctgagca taaactagac gtggcatggt
    30301 tgatcgaatc acataatcag atacatcgcc acgataacaa tgcggatagc caatgatttt
    30361 ctcctcaact tctgtcaaat cgatgatagg cctaaccttg atcgtcgtga ctggtcttgc
    30421 taaagcctga gtacatgctg ccaattcttc ttccgaaatg aattggttag atatgaggat
    30481 attatcaatg gttcctatcg ctttcattaa ttctacttgc aggccaatgg gcaagtgcct
    30541 atggtcttcc actgtcggca agccttctgc cagtagccaa gggccttcag atgctgactg
    30601 agcggtaata aaagcagccg tttcaatatc atgctcatga taaaaacgtg acatatcctt
    30661 aaaatgttgc catgacaaac cggtaaattc atgtggataa aaattatggc aaccaataat
    30721 attgctctgt tctgcatctg tcgctagcaa tgacatcaat aattgtttat cagtgctcat
    30781 attaagttca attttaagcc caaagggatt tcttgttaaa gttacaatct ctgctagagg
    30841 gagagcctcg tctaagcgta agcccgctaa cccgaaggca tgagctcgtt caataagctg
    30901 atctgaccaa ccagcttggc taataaagct tggactaacg tcagcaatta ctcgaatgcc
    30961 taattgattt gcataagcaa tgagctctgc gtagcaatga aacatctggt gatcagctgg
    31021 tgccagctgt aagagactca taaacaagcg cttggctcca tagctatgac ataagtcaat
    31081 ataagcttta ctcttggtaa catcataccg ctcagggtat agagaaaatc ctaaatcaac
    31141 catattgcct cctatttatc aaaaccattt gactcgctca acgccttaaa ccagtaacct
    31201 gattttttta tggttcgctt ttgactctct aaatccaaag ctaccaaacc atatcggttt
    31261 ttataagcat ttaaccaaga ccagcaatca ataaaagtcc acaagaggta gcctttgcag
    31321 ttggctcctt ctcccaaagc cttatgaagc tggataagat gatcctcgat aaaggtgatg
    31381 cggtagtcat cttgtatctg gccatctgct aaaaaagctt cttcaccttc gacacccata
    31441 ccattttccg tgactagcca ttcgatgtta ccatagtgtt cttttaaatt aagggcaata
    31501 tcataaagtc ctggttcata aatttcccaa ccccggtgag gattgacttt tttaccaggc
    31561 atatcataag gttcaaaata aatatctaag ataagggggt ccccctcttg ctgtgactta
    31621 ctaggtgcct gaacccgcaa aggctgataa taattaactc ccaaaaaatc aacagtattg
    31681 tttttgataa cctctaattc atcagcacta tattgaggta ataaatcagc ttcctctaaa
    31741 atggaaacta actctgctgg gtaaacaccc aaaactgatg gatctaggaa ggatttggtt
    31801 tggaaaagct ctgcgattct agcagccttg acatcttcag gagcatcact ccgaggataa
    31861 gcaggtgtca tgttaagcac aatactaatc ttgtggtcgg gatgaagctt atgacaagct
    31921 ttaaccgcca gtgaactggc cagttgtgtg ttgtaagcca cttgaactgc tgccttggca
    31981 tctactttac aagggtagtg ataataacct aaatagccac attcgactgg aacaatcggt
    32041 tcattaaagg taatccaagt gtttactaaa tcaccaaaaa gctcaaaaca ggtttttgcg
    32101 taggtttcat aagcccagac agtagctttg ttttcccagc cacctttttc ttgcaaggca
    32161 tagggaaggt caaaatgata gaggttaaca atcaatttaa taccttgagc aataatgtct
    32221 tgaaatactt ctcggtaaaa tgtcaccgcc tttggattaa cctccccgac tccttctgga
    32281 atcaatcgag accactggat tgaggtccga aaaatcgtgt ggcctgtttc tttcaaaagg
    32341 gcaatgtcac ccttatagtt ttcataaaag gttgaggttt tttctggacc aatttggtga
    32401 tgaaacttag ctgactcaat actaaaccag taatcccagt tgctaggtcc tttgccatct
    32461 ccaggaaccg ttccttcgct ttgaggccca gatgtggaac ttccccataa aaagccatct
    32521 ggaaattgat aacggtgttt tctttgtttc atatcctttg tcctttcttt gctcacttct
    32581 ctttttatta taagaagaaa aacaggtgat gtaaacgctt taaaaaatct gttttttcct
    32641 tatcatcacg gaaaataagt gatttaaagc ttgacatatt ttattatctt aaagagccta
    32701 tctaacctgc cctgctactt cttatcaaaa ccaagcccct attgacagat gccttagcct
    32761 atgtttgaat aggggtatgg cttatttaaa ctactttaca aaaaccgagt gggcactttg
    32821 gttaagctct gtcttggcca ttttaattag cgccctttta ttcggtaagc aagctccctt
    32881 agctttaata gcttctttga ttggtgtgac ctctctcatt tttagtgcta aagctaatcc
    32941 tattggtcaa gggctcgtca ttattttttc cattatctat gcctatcttt cattacgaaa
    33001 cagttactat ggagagttaa tgacctatct tttcatgacc ctccctatga ctattttttc
    33061 actttttact tggttaaacc atccttttga agggaaaaaa tcacaagtga ctatttcacg
    33121 attaacaccc actgatcgaa gatgtctttt cgtttttact atactggtca ctcttatttt
    33181 ctacggcatc ttggcttcta ttcaaacagc ctatttactt gtctccactt tatcgattgc
    33241 cacttctttc tcagccgttt atctcagcta taagcgaagc ccttattttg ctttggctta
    33301 tggactcaat gatctagtcc tcattctctt atggatgcat gctgctcaaa cagatgccag
    33361 ccaatatgct gtggtcatct gctttgccac ctttcttatt aatgatagtt acacttttta
    33421 tagttggcta atgctccaac gttaccaaga aaaaaaggtc aaaaaaggat gagggcctaa
    33481 gcctcatcct ttttcaattt ttcacgttct aagcgcaaac gtctattggg atttaaaaga
    33541 ttaaacaatt cttctaattt ctcagcattc caaacatctg ctgccgatac aaaatttcca
    33601 tccttatcct taaaggatat cggtttatca cccataatca gaaacctcca tcttaaagat
    33661 aaaacacaag gttgctatgg caatgccatt tctaaagacc acattaatcc acaaattcaa
    33721 attcaaattt gccaatacga acaggatccc cgtcttttgc tccacgttca cgaagggctt
    33781 cgtcaacccc cataccgcgc aattgacggg caaatttcat gatggattcg tcacgttcca
    33841 tattggtcat gacaaagaga cgttccaatt tctcaccaga caagacccaa gtagcatcat
    33901 catctcgggt aatctcaaag tctttttcag tttctgcaaa gccatagtaa gcttcctcgt
    33961 ccaccagatc agcttcatca tataataaga attcatccgt cttagcaagt aattctgctg
    34021 ttgcttctaa caagttctct aagccttgat gtgctaggct tgaaataggg aaaatcattg
    34081 gtaggtcatc aaactcgtca tattgggcag ccaatttttt cttgaaggct ttcaagtttt
    34141 cttgagcctc tggcatgtcc attttattag ccacaataat ctgtgggcgc tccatcaatc
    34201 gcaaattata ggtttccagc tcgttattaa tagaaacata atcttcgtaa ggatcacgac
    34261 cctcactagc agacatgtca atcacatgaa gaataacccg tgtccgctcg atatgacgga
    34321 ggaattgagt tcctaaacca accccttggc tagcaccttc aatcaaacct ggcagatctg
    34381 ccatagcaaa gctatcacct gacttggtac gaaccattcc aagattagga acaatagtgg
    34441 taaaatgata ggcaccaatt ttcggtttag ctgatgacac aacacttaac aaggttgatt
    34501 tcccaacaga tgggaatccg accaagccaa cgtcagctaa gattttgagt tctaactcta
    34561 actgacgttc ctcacctggc tcaccatttt cagcaatctc tggcgcagga ttacgaggag
    34621 ttgcaaaacg aatattccca cggccaccac gaccaccctt agcaatgacc acttcttgac
    34681 catgttctac taagtctgta attacttttc cagtttcagc atcacgaacc gttgtccctt
    34741 gaggaacaaa gacaatcaaa tcttctgcac cacggccgtg catgcctttg gtcatacctt
    34801 tttcaccaga tttcgccttg aatttacgat tataccggaa atccatcaag gtacgcaaac
    34861 cttcgtccac tcggaagata actgagccac ctttaccacc gtctcctccc caaggaccgc
    34921 catttgggac gtacttttca cgacgaaaag ctaccatacc atcgccacca cggcctgctt
    34981 ggacactgat ttttgccgta tctaaaaaca tactcatact ttttttattc tctaactttc
    35041 ttttacttta aaaaaacgcc tttcagcgtt tccttacatt aatactgata gggcactcgc
    35101 aataagcccg ccaacagtta caagaaccat taggataaca acaaacattg ttactttttc
    35161 aaaggttgtt tttttgcgag gtccattttc tccaaatgcc acgttaaata cctcatctat
    35221 tgatttttct tcttatatat taacatgaaa gatcgtttta ggcaaatacc agatgaatat
    35281 ttacgctatg tagactatta ctgagtattg tatcttgtga atttcatatg aatatgatac
    35341 attagcattt gcaaaataat gttacagata aaaacctcct cgtctggtga actgcacccc
    35401 aaaagttaga cacaaagtct aacggttggg gtgctatttt tttatgaaat ttaatcaaga
    35461 aacgaaagtt aagatttacg agttacggca aatgggagag tccattaaat ccatatcaaa
    35521 aaagtttgat atggcagaat ccgatctcaa atatatgatt cgcttgattg ataggtatgg
    35581 ggtaaccatt gttcaaaaat gtaagaat
//
LOCUS       DAUGUF010000021        35151 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUGUF010000021 DAUGUF010000000
VERSION     DAUGUF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35151
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.021"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(160..1437)
                     /locus_tag="VIB71_001000"
     CDS             complement(160..1437)
                     /locus_tag="VIB71_001000"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEQ8822744.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGRMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(1424..2599)
                     /locus_tag="VIB71_001001"
     CDS             complement(1424..2599)
                     /locus_tag="VIB71_001001"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEQ8822745.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAICFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
     gene            2808..3647
                     /locus_tag="VIB71_001002"
     CDS             2808..3647
                     /locus_tag="VIB71_001002"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEQ8822746.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMFAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            3727..4224
                     /locus_tag="VIB71_001003"
     CDS             3727..4224
                     /locus_tag="VIB71_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEQ8822747.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            4544..5773
                     /gene="clpX"
                     /locus_tag="VIB71_001004"
     CDS             4544..5773
                     /gene="clpX"
                     /locus_tag="VIB71_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEQ8822748.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELSEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            5783..6382
                     /locus_tag="VIB71_001005"
     CDS             5783..6382
                     /locus_tag="VIB71_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEQ8822749.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            6530..7273
                     /locus_tag="VIB71_001006"
     CDS             6530..7273
                     /locus_tag="VIB71_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822750.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(7331..9430)
                     /locus_tag="VIB71_001007"
     CDS             complement(7331..9430)
                     /locus_tag="VIB71_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ8822751.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPHRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQKDQ"
     gene            9808..10491
                     /gene="rpiA"
                     /locus_tag="VIB71_001008"
     CDS             9808..10491
                     /gene="rpiA"
                     /locus_tag="VIB71_001008"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEQ8822752.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     IVLEAPKAG"
     gene            10568..11779
                     /locus_tag="VIB71_001009"
     CDS             10568..11779
                     /locus_tag="VIB71_001009"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEQ8822753.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTIPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIFANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLGHLK"
     gene            11798..12239
                     /gene="arsC"
                     /locus_tag="VIB71_001010"
                     /pseudo
     CDS             11798..12239
                     /gene="arsC"
                     /locus_tag="VIB71_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     frameshifted; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
     gene            12223..13032
                     /locus_tag="VIB71_001011"
     CDS             12223..13032
                     /locus_tag="VIB71_001011"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8822754.1"
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEMAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            13695..14408
                     /gene="deoD"
                     /locus_tag="VIB71_001012"
     CDS             13695..14408
                     /gene="deoD"
                     /locus_tag="VIB71_001012"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ8822755.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            14401..15189
                     /locus_tag="VIB71_001013"
     CDS             14401..15189
                     /locus_tag="VIB71_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEQ8822756.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRIIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADVLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRCEPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(15269..16174)
                     /locus_tag="VIB71_001014"
     CDS             complement(15269..16174)
                     /locus_tag="VIB71_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ8822757.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLSDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHSKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            16396..16932
                     /locus_tag="VIB71_001015"
     CDS             16396..16932
                     /locus_tag="VIB71_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822758.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     ETFIKYYESPKVSTGEFE"
     gene            17209..17901
                     /gene="pyrF"
                     /locus_tag="VIB71_001016"
     CDS             17209..17901
                     /gene="pyrF"
                     /locus_tag="VIB71_001016"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEQ8822759.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            17959..18588
                     /locus_tag="VIB71_001017"
     CDS             17959..18588
                     /locus_tag="VIB71_001017"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEQ8822760.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFVYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            18785..20239
                     /locus_tag="VIB71_001018"
     CDS             18785..20239
                     /locus_tag="VIB71_001018"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEQ8822761.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALKQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            20357..21220
                     /locus_tag="VIB71_001019"
     CDS             20357..21220
                     /locus_tag="VIB71_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ8822762.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            21249..21899
                     /locus_tag="VIB71_001020"
     CDS             21249..21899
                     /locus_tag="VIB71_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8822763.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
     gene            22032..22685
                     /locus_tag="VIB71_001021"
     CDS             22032..22685
                     /locus_tag="VIB71_001021"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEQ8822764.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            22817..24085
                     /locus_tag="VIB71_001022"
     CDS             22817..24085
                     /locus_tag="VIB71_001022"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEQ8822765.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(24143..24784)
                     /gene="plsY"
                     /locus_tag="VIB71_001023"
     CDS             complement(24143..24784)
                     /gene="plsY"
                     /locus_tag="VIB71_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEQ8822766.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            24919..26868
                     /gene="parE"
                     /locus_tag="VIB71_001024"
     CDS             24919..26868
                     /gene="parE"
                     /locus_tag="VIB71_001024"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEQ8822767.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVETGHVYIALPPLYKMSKGKGKTEKVSYAWTDGEL
                     EDLRKEFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            26959..29418
                     /gene="parC"
                     /locus_tag="VIB71_001025"
     CDS             26959..29418
                     /gene="parC"
                     /locus_tag="VIB71_001025"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEQ8822768.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEVRLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            29496..30563
                     /locus_tag="VIB71_001026"
     CDS             29496..30563
                     /locus_tag="VIB71_001026"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEQ8822769.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAARLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            30627..30857
                     /locus_tag="VIB71_001027"
     CDS             30627..30857
                     /locus_tag="VIB71_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEQ8822770.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            30918..30998
                     /locus_tag="VIB71_001028"
     tRNA            30918..30998
                     /locus_tag="VIB71_001028"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30952..30954,aa:Tyr,seq:gta)
     gene            31050..31121
                     /locus_tag="VIB71_001029"
     tRNA            31050..31121
                     /locus_tag="VIB71_001029"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31082..31084,aa:Gln,seq:ttg)
     gene            31248..32453
                     /gene="rpsA"
                     /locus_tag="VIB71_001030"
     CDS             31248..32453
                     /gene="rpsA"
                     /locus_tag="VIB71_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEQ8822771.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            32566..32637
                     /locus_tag="VIB71_001031"
     tRNA            32566..32637
                     /locus_tag="VIB71_001031"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32599..32601,aa:Arg,seq:ccg)
     gene            complement(33000..33302)
                     /locus_tag="VIB71_001032"
     CDS             complement(33000..33302)
                     /locus_tag="VIB71_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822772.1"
                     /translation="MTYELCLEYGTYPLSRVYAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            33502..34488
                     /locus_tag="VIB71_001033"
     CDS             33502..34488
                     /locus_tag="VIB71_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEQ8822773.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWLVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            34559..34750
                     /locus_tag="VIB71_001034"
     CDS             34559..34750
                     /locus_tag="VIB71_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822774.1"
                     /translation="MQQDTSERGHQAHFVMQSHQQRRRQHQLCLEPFQKNCEFLYYEI
                     EKVKLDSEDCLTINPLGMV"
     gene            34883..>35151
                     /locus_tag="VIB71_001035"
     CDS             34883..>35151
                     /locus_tag="VIB71_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HEQ8822775.1"
                     /translation="MDFLTGDFPLVFRPMYNPHRYTISQDNQALEKVKQASYKRMDIA
                     MTHLDGLIGDSGHVYRDQQTIADAYAYAMALWSQKTPKSYENYPHL"
BASE COUNT        10988 a         6202 c         7294 g        10667 t
ORIGIN      
        1 tatttataaa tacctcatca aactcagaat agagtagatg agtaaataga gtatgttatg
       61 gagactattt ctaagacttg tatgtataga aacaaagatt aaacacccat gtaaaccaat
      121 tgtttacatg ggtgtttgcc ttatattagt tgtttaaatc taagactgtc ttagctggga
      181 taagtaaaaa tgtgcttttt ctagatttat tggtttatca gctagtaaag cattaactaa
      241 aggagcaatt tcgtcttggg ttgcccccgc caaaagagct aatgatttcg catgtagttt
      301 catgtgacca gcttggatgc cagatgaggt cagagctttt agtgcagcaa agttttgagc
      361 taaccccaca gatgcaatca attgggctaa tgttttggca tcaggttgat taagaagatc
      421 atgtgcgata gaaacagtag ggttaagccc gatagatccc cccttactag caataggcat
      481 agggagggtc attcggccaa gcagaacttg tttatcttga tcaaaatgcc actgactaag
      541 tccttgatag ctaccatttc ttgaggcata agcatgggcc cctgcttcaa tagcacgcca
      601 gtcatttcct gtggctatta ccactgcatc gataccatta aaaatacctt tattatgagt
      661 agtagcccgg taaggatcta cttgagctag tcggctggct agctctattt tttgagctaa
      721 ctgtagggat tttgttttat cgcgatctaa aaggcgcacg ggaatctcac aactagtagt
      781 aacaagcgac tctgttgcgt aattagataa aatcgccatt agacaatgcc ccttagacag
      841 tcttgttaaa tcaggaacaa gagcttccat catagtattg accatatttg ctcccatagc
      901 ttcttgggta tcaacagtca gatagaaaat caaaaactct cctttttctt ccaaatgaat
      961 ggttctagcg cctccacctc ttttaacaat ggaaggataa gctttatttg ccaatgcaat
     1021 tagctttttt gttttatgaa ggatggcggc tttagcgtta tctatttggt cgatatcgta
     1081 aagaacaatt tgaccaatca tttgtcggtt tagggtttga gctttaaaac cacctgagcg
     1141 tttgattagt tttgctgcga aagatgctgc agcaacaaca gaaggttctt ccgtgacaaa
     1201 aggcatctga taagttgaac cgttgacaag aaaatcagga gctatgctaa agggcaaagc
     1261 caatcgtcct aagacatttt cagtcatttg attagctgtt tggataggca aaagaacgtc
     1321 tgttttgagt tgatttaagt tttcagcatt aagtagttta aatttttcga taagttggag
     1381 gcgttcttcg aatgttttct ttgaaaaacc gctccagtta agattagttt ttgtcattgg
     1441 tatgatagat ccttcgatgc tccttgatgg ctgttagagc aaattttcca gttaagtaaa
     1501 tgtcaaaatt ggcattacca ttatcatcta attggacttg ttcgtagaaa aggtcttcgt
     1561 atttagaaac ggaaagacgt gttcgttgat ccagtaaagc ttgtcgatta gtcattaaca
     1621 ttttatcgta cccagcaact aactgaccgg aataaaattc acttacggca ccggaaccat
     1681 agctaaaaaa accaatttta tctccagatt gtaatacttt actattttca agtaaagata
     1741 acaatcctag ataaagtgag ccagtataaa tatttccaat ttgtttgcta taagtaatag
     1801 aagcttgaaa ggcttctatt agtttttctc tgtgttcagg aggtactgtg ttatccataa
     1861 tgttatttag accttttagg gctaacttgg gaaatggaat atggaaacaa attgcagcaa
     1921 aatcagataa ctgaaggttt tctcttttct gataagcttg ccacgtggtt tctaagcaat
     1981 tgagatattg cttggtagag taaataccat caacataagg tgtgaaacta tagttaggcc
     2041 tccaaaagtc cataatatcc ctagtttgag ccacattatc tttatttaga gcaagaatac
     2101 gagggttagc agttaccaaa agagcaatac taccagagcc ttgagttgat tcgccaggag
     2161 atcctacacc gtatctagca atatcactag caataacaag gacacgagaa tctggcttag
     2221 aagccacatg cagtttagca tagtctagag cagcagttgc gctatagcag gcttgtttta
     2281 cttcaaagga acgtgcaaaa ggctggatac caactaagtg atgtacatag atagctgatg
     2341 cctttgactg atcagtactc gattcagttg ccaaaataac catatcaatc ttagatcgat
     2401 cttcgtcggt taaaatttgg tctgctgcag aagcagctaa agtaataatg tcttcagtga
     2461 ttggtgccac actaaaagac tcaatgagta gcccttgact aaattttgct ggatccactt
     2521 ggcgtgcaag cgctaaatct tccaatttca agacatattg actggttgca aaaccaatct
     2581 tatcaattcc aattgtcata tttgtccttc ttttagttat ttttatagtc ttacccattc
     2641 tatcacattt tactgcaaaa ttagactgat aaagttattt gttttatcct ttaatagtta
     2701 aaatgttcat gaccacatga agtttttcga atgtttattt attctggtat tttttggtaa
     2761 aattagttag aatagtatga agtatgctta cagaaaggtt attagagatg acaaaagctg
     2821 accagatttt taaagctaat attcaaaaaa ttataaacga aggatcattg agtgagcaag
     2881 cacgtcctaa atataaagat ggtcgaacag ctcattctaa gtatattact ggggcgtttg
     2941 ctgaatatga tttagctaaa ggagagtttc ccatcacaac tttacgaccc attccaatta
     3001 aatctgctat aaaggaatta ttttggatat atcaagatca gtctaacagt ttagatgtgc
     3061 tagaagctaa atataatgtt cattattgga atgaatggga agttgaccag acacgtacta
     3121 ttggacaacg ttatggtgct gtagtcaaaa aacatgatat catctcaaaa atactaaagc
     3181 aattagcaga aaatccttgg aatcgtcgta atgtcatttc tctctgggac tatgaagcat
     3241 ttgaggagac aaaagggttg ttgccatgtg cctttcaaat catgtttgat gttagacgtg
     3301 taggggaaga tctttattta gatgctagtt tgacgcaacg ttctaatgac atattagttg
     3361 ctcatcacat caatgccatg caatacgttg ccttgcagat gatgtttgct aaacatttcg
     3421 gatggaaaat aggtaagttc ttttattttg ttaacaattt acatatttat gacaaccaat
     3481 ttgatcaggc tcaagaatta ctaaaacgac agccagttgc cagtcagcct aagcttgttt
     3541 taaatgttcc agatggtact aatttctttg atattaaacc agatgatttt gaattacaaa
     3601 attatgatcc agtgaagcct cagttgcact ttgaccttgc tatttaaact ttatttagat
     3661 tttttgtgag cattttgttc ataaatttgg taaaataaat agagtttaaa atgaaggaaa
     3721 taattaatga caaaggaaat tattgctatt tgggcagagg atgaagcagg gcttattggt
     3781 gttgcgggta agttaccatg gtatttacca aaagagttag aacattttaa aaagacaacg
     3841 ctacatcaag caatcttaat gggccgtgtg acttttgaag gaatgaattg caaaagactt
     3901 cctcaacgtc aaacccttgt catgacaaga aatagagatt atcaagtaga tgaggtgttg
     3961 acaatgacta gtattgaaaa agtcttggag tggtaccatg cgcaggataa aacactttat
     4021 atcattggtg ggaataaggt tttagaagcg tttaatggtt attttgatcg tatcataaaa
     4081 acagttatcc atcatcgttt taaaggagat acctaccgac ccaatctaga ttttagtcat
     4141 ttcacgcaag aaagccaaac gttctatgct cgagacgcta aaaatcctta tgattttacc
     4201 gttactgctt taaaacacaa atagtctgag gagatgataa gcgatgcaac gtagtatttt
     4261 tggagtattt acggcttttt tgtgcgtgat ttgtgttctt tgtgccatcc cagcttttaa
     4321 aaagaatcgt tatggcttag gaagtctgtt cttattaaat gcgtttacta atctggttaa
     4381 tagtattcac gccttctatg gtacattgtt ttgagatgcg acttgcaaag acagcactgg
     4441 tgaagattta gctatcaagc aagaatcacc aaaaaccaat acaacacatt gactaatatt
     4501 aaaattcagt aaaagataag agaaagtaag agaattataa gaaatggcag gaagtagaac
     4561 taacgatatt aaagtatact gttcattttg tggtaaaagc caggatgacg ttaaaaaaat
     4621 tatcgcagga aataatgttt tcatctgcaa tgaatgcgta gctttatcac aagaaattat
     4681 aaaagaagaa ttgtctgaag aagtccttgc cgatttgaca gaagttccaa aaccaaaaga
     4741 gctccttgat gttttaaatc aatatgtggt tggtcaagat cgtgctaaac gtgctttatc
     4801 agttgctgtg tacaatcatt ataagcgtgt ctcgtttaca gaaagtcgtg atgacgatga
     4861 tgtggattta caaaagtcta acattttgat gattggacca acaggttcag gaaaaacctt
     4921 cttagcacaa actctggcta aaagcctcaa tgtaccattt gctattgcag atgcaacttc
     4981 tttgactgaa gcagggtatg ttggagaaga tgtggaaaat attttactca aactgattca
     5041 ggctgctgac tataatgtcg aacgagcaga gcgtggtatt atttatgttg atgaaataga
     5101 taagattgct aaaaaaggtg agaacgtatc tatcacacgt gatgtatctg gtgaaggtgt
     5161 acagcaagcc cttcttaaaa ttattgaagg tacggtagca agtgttcccc cacaaggtgg
     5221 gcggaagcac cctaatcaag aaatgatcca aattgataca aaaaatatct tgtttattgt
     5281 tggcggggct tttgatggca tcgaggagat tgttaaacaa cgtttaggtg aaaaagttat
     5341 tggttttggt caaaacagcc gtaaaattga tgacaatgct tcttatatgc aagaaattat
     5401 ttcagaagat attcaaaagt ttgggcttat tccagaattt attggccgct taccagttgt
     5461 ggcagccctt gaacaactta aaacatcaga tttgattcga atcttaacag agccaaggaa
     5521 tgctcttgtc aagcaatatc aggcccttct ttcctatgat ggggttgaat tagaatttga
     5581 taaagcagct cttgaagcta tcgcaactaa agcgattgaa cgtaagacag gagcacgtgg
     5641 tcttcgttct attattgaag aaacaatgct tgacattatg tttgaaattc caagccaaga
     5701 agatgtcaca aaagtgcgta tcaccaaggc tgctgtcgaa ggcaagtcaa aacccgtttt
     5761 agagacagct taaggagaaa taatggctga agaacaagtc ttaaataccc ataacgcctc
     5821 aattttattg agtgctgcca ataaatctca ttacccccaa gatgatttgc cagaaattgc
     5881 cctcgctgga cgttcaaatg ttggtaaatc aagttttatt aataccatat tggggcgcaa
     5941 aaatttggca agaacctcaa gcaagccagg aaaaacccaa ctattaaatt ttttcaatat
     6001 tgatgacaag cttagatttg tggatgtccc tggttatggc tatgccaagg tttctaaaag
     6061 tgaacgggcc aaatggggaa agatgatcga agaatactta accaccagag ataatctgcg
     6121 tgctgtcgtg agtttggttg atttacgtca tgccccttca aaagaagata ttcagatgta
     6181 tgactttttg aagtactatg acattcctgt tattgttgtg gcaaccaaag cagataagat
     6241 tcctcgtggc aaatggaaca aacatgagtc tgtggtcaag aaagctttga attttgacaa
     6301 atctgacact tttatagtat tttcttcggt agaacgtatt ggtatcgatg attcttggga
     6361 tgctatttta gagcaggtct agcgataggt gttgatttat ctatgctaaa acattctcag
     6421 tagagggtgt ttttcttatc gaaaacataa aaaatcatag ttaggtttac cgattttact
     6481 tgacgcctta atgatgacat gctagtattt tatattaagg agatgagtca tgacacaagt
     6541 agcccaaggg cgctctaaag gaaagtcatt gttatgccat caatgcaatg ccctttttgt
     6601 atttattatt tttcttatct tgcttgctgt actttttggt gttcgatatc gtaatagctc
     6661 tattgaaggt atctggcgaa caacaagcat tgatcagaag ttaggcgatg attttgctaa
     6721 acgtcttact ggtttgcatc agagccctct tattgatgat agtttattaa cgtcatctca
     6781 gatgatacta acagttaaaa ataacaacgt tgacttgagt tttagtgttc aagttgaacg
     6841 agacattttt gtcaaacgtt tagctgctta tcaccaaaat gaattattaa agacattaaa
     6901 ggaaaatcat ttagttgttg gtgacttgag tagtaaagaa cgccaaatta ttgagaatag
     6961 tatgccagct agccatgaat tagaaatgat tttagatcaa gcttttgaga aattagcttc
     7021 tcagatcgga ggcaaatata atcaaaaaac aggacattta tctgctgtgg ttctcaaagg
     7081 aaaagttaat cgtattttgc acaccattga tatcaaagaa gaagtagcag cgggacatac
     7141 ttctttttca aaaggattgc tcacacctaa tggttatttt gattacacca gatttggaaa
     7201 gaaacttgag ttattaggcg atgaaaaaat tatttttaaa aaagcgctaa aaaaaagtcc
     7261 gtcaagtgta taacgtagtc acaagacgga ttttttcatg ttttgaaaat tattcaattg
     7321 aagaagttta ttactgatct ttttgcctaa tcactagttg tccttctttt aggattgcct
     7381 gaagtttttt gacttctgga tggtcaagat aataatcagt tatacggtca cgaatttcct
     7441 gttcgataat acgtcgtaat ggacgagctc ccatagcgtg attgtaccct aaatctatca
     7501 aatgagcttt agcgtcatca gcaatcgtta aactaatacc tttttttgcg gtggtttgat
     7561 ttacttcagc tagcattaaa tcaacaattt cttctaaatt ttctttttgc agatgattaa
     7621 atttaatgat actattaaaa cggttcaaaa actctggtct gaaataaggt gcaatgcgat
     7681 ccataatgtt agacccagaa gtttccgtat cttgttggcc aaaaccggca tttgatgtag
     7741 caataataac ggtattttta aagttaatag tatttccttg tccatctgtc aatcgtccat
     7801 catctaacac ttgtagaaga agtgtaatga tttgaggatc agctttttca atttcatcta
     7861 gtaagacaat agcataaggg ttacgacgaa cacgctcagt tagggtatta ttattatcat
     7921 cgtagccaac ataaccagcc gttgtcccaa tcaattttga cacagcagtg cgatcgttat
     7981 attcggacat atcaagtcga ataatagcat ctttggaacc aaataaatca agtgctaatt
     8041 gtttagctaa ctctgtttta ccaacaccag ttggacccac aaaaaggaaa gaacctattg
     8101 gacggttacc atcatcaaaa cctgctcgat ttcgtcgaat agcacgtgct actgctgcga
     8161 cagcctcatc ttgtccgatg acatggcttt ttaagcggct gctaattcct ttgagccttt
     8221 ctaaatcatt agtccccatg ttagagacag gaataccagt taagcgctct acagactctg
     8281 cgatatcatt gactgtagca gtaacatttt ggctttggtt atgttgctca atttgctttt
     8341 gtaatgtttc aatccgtgtt tttgctgcta aagctttttc aaagtcttct ttggcgacag
     8401 ctttttcttg actctctttt tgtttagcta tttcagtttc gagtgttttt aagtcagtga
     8461 ccgggtgttg cgcagctaaa tgagcagctg tcatatccag taagtcaatc gctttatctg
     8521 gcaggctacg gtgtgggatg tattgaatag aataatcaac agcagctttt agaacattat
     8581 caggaagggt aatatggtgg tgttgttcat aaagattacg aatacccatt aaaatgtgaa
     8641 aagtatcttc agctgatggt gcattcactt taacttcatt aaagcgacga gcaagagcag
     8701 cattttttaa aatagtattg cggtattcgt cttgagtagt agcaccaatc agtgttaatt
     8761 ctcctcgtga caaggctggt ttaagaatat ctgcaagtcc ctttgagcct gaatcactgc
     8821 ttgtggcacc agcaccaact atttgatgaa tttcatcaaa aaataagatg atattcccag
     8881 cttcttttac ttcttgaatc aagttttgaa tggtctcttc aaaggaacca cgatactgtg
     8941 taccagcttc aagactagaa atatcaattg atacgatttc tttgttttta atagcggctg
     9001 ggacatctcc attaacaatg gcttgagcta aaccttcaat gactgcagtt ttaccgacac
     9061 cagcatctcc gacaaggaca ggattatttt tagttcgtcg tgccaagatt tcagcggtat
     9121 cttgaatttc tttgttacga ccaatgacgg ggtcaagatg cccttgacga gcttcttgtg
     9181 ttaagttagt tccgagttga gtcaatacac tatcagcttt aggtgttaac atttgagaat
     9241 ttgttgcttt ggttgtcgct acagggagtt gtcctgtttg acgatagtgt tggaattctt
     9301 cgggagttat ttcgcgaccg ttaacgagat agcggggatt ttcgctacga taaccaccca
     9361 tgtttgccat taattggttg aaaatatcat ccatatttac aaaaggatct ttaccagaaa
     9421 aatgtgtcat atcagttacc tcgcaataaa aaatagacta taagatgttt gtaagcagtc
     9481 gcagaatcgt tgttaggatt tcacatgata ggaaaccctt tgctaataaa atgattcaga
     9541 cattattttt actcatctta tagtattatt ataatcaaaa ggtcagtaaa ggtcaaacaa
     9601 aaacacttga ttttcaaaaa gctaaataaa cacgaaaagt aagtgcttat atgatgactt
     9661 tagaataaat cataagtttt aaaaagatca tcctattcta tagcacttag gctgtcaatg
     9721 agagaaaaac aaatgttttc attaacaagt tggcgctttc atggtataat aaagtgctaa
     9781 gacgcaattc tattataagg gggaatcatg gaagcactca aaaaaattgc cggtgttacc
     9841 gctgcgcaat atgtgactga tggcatgacc attgggcttg gaactgggtc aacggcttac
     9901 tattttgttg aggaaattgg ccgtcgcgta aagcaagaag gactgcaagt ggttggtgtg
     9961 actacgtcaa gtgtgactag caagcaagca gaaggcttag gcattccttt aaaatcgata
    10021 gatgatattg atagcattga cctcaccgta gatggtgctg atgaagtgga taaggatttc
    10081 aatggaatca agggtggcgg cgcagcctta ctaatggaaa aaattgttgc aacaccaaca
    10141 aaagaataca tctgggttgt tgatgcttct aaaatggtag agcatctggg tgcctttaag
    10201 ttaccagtcg aagtcgttca atatggtgct gatcgtttgt tccgtgtctt tgaaaaagct
    10261 ggttacaaac cgtcttttcg tatgaaaggt gatagtcgtt tggtgacaga catgcaaaac
    10321 tatattattg atcttgattt gggttgtatt aaagatcctg ttgcttttgg tcacctgcta
    10381 gatggaacag ttggtgttgt ggaacacggt ctctttaatg gtatggttga taaggtgatt
    10441 gttgctagta aagacggcgt tattgtttta gaagcgccta aagcaggcta gtcttagcat
    10501 ataacagtgt taatatattt tataggtatt ggggagtcaa ccgtaacctc ccctagattg
    10561 gagacttatg tcaaaattta atcgtattca cttggttgtt ttagactctg tcggtattgg
    10621 tgcagcgcca gatgctgaca aattctttaa tgctggtgta gctgatacag attctgacac
    10681 cctcggtcat atttcagaaa cagcaggctt atcggttcca aatatggcaa aaattggact
    10741 tggaaacatt tctcgtccga taccactaaa aactattcca acagaagaca atcctactgg
    10801 ttacgtgacc aaattggaag aagtatctct tggaaaagat accatgacag gccattggga
    10861 aattatgggc ttgaacatta cggaaccttt tgacactttc tggaatggtt tcccagaaga
    10921 gattttaact aagattgaag aattctcagg tcgcaaaatt attcgtgaag ctaataaacc
    10981 ctattcagga actgcggtta ttgatgattt tggtccgcgt caaatggaaa caggtgagtt
    11041 gattgtttac acctcagcag acccagtgct tcaaattgca gcccatgaag acattattcc
    11101 tgtggaagag ctttacaaga tttgtgaata tgctcgctcc atcacgcttg aacgccctgc
    11161 ccttttaggc cgtattattg cgcgtcctta tgtaggcgaa ccaggaaact ttacacgtac
    11221 ggctaaccgt catgactatg cagtgtctcc tttccaagat accgttttga acaaactggc
    11281 tgacgcaggc gttccaactt atgccgttgg taagattaat gacatcttta atggttcagg
    11341 tattacaaac gacatgggac acaataagtc gaacagccat ggtattgaca cgcttattaa
    11401 gactcttcaa ttacctgagt ttactaaggg attctccttt actaacctcg ttgattttga
    11461 tgccaacttt ggtcatcgtc gtgacccaga gggttatcgt gactgcttgc atgaatttga
    11521 caatcgccta cctgaaatct tcgcaaatat gaaagaagac gatttgcttc tcatcactgc
    11581 tgaccatggt aatgacccaa cctatgcagg caccgaccac actcgtgaat acattccatt
    11641 gcttgcctac tctgcatcct ttactggaaa tggtcttatt ccacaagggc attttgcgga
    11701 tatttcagca actgttgcag aaaattttgg agttgataca gccatgattg gggagtcatt
    11761 ccttggtcac ttaaaataag aaagttagta attgataatg gaagaaatca cgatttatca
    11821 taatccaaac tgtggcactt cacgtaatgt tcttgccatg attcgccatg caggtattga
    11881 gcctactatt attgagtatt tgcagacgcc acctaatcgg gagactttaa ttgagctctt
    11941 acaatcgatg ggaatctctg cgcgagaact cttgcgaacc aatgttcctg aatttgaggc
    12001 tcatggatta gcaaatcaag cagtagctga gaaagacgtt attaatgcca tgttggcgga
    12061 tccaattttg atcaatcgtc ctattgttgt gactcgcaaa ggagtaaaac tttgtcgtcc
    12121 ttctgagacc ttactggata ttcttcctgt tcccctgcct agtccttact atgaaagagg
    12181 atggcgagag tgtgaaccct attgaggtaa aaggagaaaa agatgtcatt gatgactaaa
    12241 attaacgaaa caaaagactt tttagttact aaaggaattg aaactcccga atttggatta
    12301 attctgggtt caggccttgg tgaacttgct gaagaagtag aaaatgctat tgttattgat
    12361 tatgcagata ttccaaactg gggcaagtca acggttgttg gccatgctgg aaagttagtt
    12421 tacggagatt tagctggccg taaagtgctc gccttacaag gacgtttcca tttttacgaa
    12481 ggaaatccgc ttgaagtggt gactttccct gttcgtgtca tgaaagctct tggatgtgaa
    12541 ggcgttcttg tcacaaatgc agctggtggt atcggctacg gcccaggtac cttgatggca
    12601 atcacagacc atatcaatat gaccggaaat aacccactaa ttggtgaaaa cttggacgag
    12661 tttggtccac gcttccctga tatgtctgat gcctatacta aggtttatcg caataaggca
    12721 catgaaatgg ctgaaaaaat gaacatcaaa ctagaagatg gtgtttatat gggcttgact
    12781 ggtccaactt atgaaacacc agcagaaatc cgtgctttca aagtattagg agcagatgct
    12841 gttggcatgt caactgtacc agaagttatt gtggctgctc attctggact taaagtactt
    12901 ggtatttcag ctattacaaa ctttgcagct ggttttcaat cagaattgaa ccatgaagaa
    12961 gttgtggaag tgacccaaca tatcaaagaa gatttcaaag gtcttgttaa agctatttta
    13021 gcggagttgt aggacgaaca aaatcaactg gagcattatt acaggaatgt tattttatgt
    13081 cgtcagtttg gcacatctgt tcgcaataaa aaaatcaaaa aataatcacg gagtgtgagt
    13141 tccatgaatg ttgaactcag attctagctt ttctaactaa cataaccaac gaagggaaag
    13201 agacgtattc ggtttaaatt gagtatggac tcgaacattt cttcgtatta atttttaaat
    13261 aataaaggaa agagagttag tcctttctta tttgaactcg atttttagct ctcttctatt
    13321 caatatcaat tatgaaagga atggggttgt attcaattga atacgggcgg aaagctcgga
    13381 aactagataa actaactttt gagctcacac atggcgttag ttccctaaat ttcagtcgct
    13441 ttctgtccgc cctctgacct tctacaaaat aaaaggaaag gtagggctaa ctgtattcat
    13501 tgaattgaat acgggcggag aactgttttt cttccttata aaaaataaaa aaataagaaa
    13561 ggtgagggct gagttcatta atttgaattc gggctaagga cttggtcaaa aagataagtt
    13621 gtctagaaaa tcaggatttt ctgccaactt cctattttgc catcgttctt ttaacgccct
    13681 cagtatcata atttatgtct atccatattt ctgccaaaaa aggcgatatt gctgataaaa
    13741 ttcttctacc tggagatcct ttgcgcgcga aatttatcgc tgaaaatttc ctagaagatg
    13801 cagtgtgttt taacgaagtg cgtaacatgt ttggctacac aggaacttac aaagggcacc
    13861 gcgtttctgt catgggaact ggtatgggga tgccttcgat ctctatctat gctcgtgaat
    13921 taatcgttga ttacggtgtc aaaacattga tccgtgttgg tactgcgggt gcgattgacc
    13981 cagaagttca tgtgcgtgaa ttggtgcttg cccaagcagc agcaaccaac tcaaatatta
    14041 tccgtaatga cttcccagaa tttgatttcc cacaaattgc tgattttggt ttacttgaca
    14101 aggcttacca tatcgccaga gaaatgggag taacaactca cgttgggaat gtgctttctt
    14161 ctgatgtctt ttacactaac atgcctgagc gtaatatggc tcttggtaaa ttgggtgtta
    14221 aagccatcga aatggaagca gcagctcttt actatttagc tgctcagcac catgtcaaag
    14281 cccttggaat catgacgatc tcagataact tgaatgatcc aaccgaagat actacagctg
    14341 aagagcgcca aaccactttc actgatatga tgaaggtcgg cttggaaacc ttaattgcca
    14401 atgactaata atcaaacact agacatcctt ttggatgtct atgcttataa tcacgccttt
    14461 agaattgcta aagccttgcc aaatatccct aaaactgccc tctatttact agagatgtta
    14521 aaagagcgca gagaattgaa ccttgccttt ctggcggaac atgcagcaga gaatcggatc
    14581 attgaagacc agtaccactg ttcattatgg cttaaccaat cgcttgaaga tgagcagatt
    14641 gccaattaca ttttggattt agaagttaaa gtaaaaaacg gtgctattat tgatttcgtt
    14701 aggtcagtgt cgcctattct ttaccgactt tttctcagac taatcacgtc agaaattcca
    14761 aacttcaagg cttatatttt tgatacaaag aatgaccaat atgatacctg gcattttcag
    14821 gccatgttgg aatctgatca cgaggttttc aaggcttacc tgtctcaaaa gcagtctcgc
    14881 aatgtgacga ccaaaagctt agcagacgtg ttgacgttga cctccttacc tcaggaaatc
    14941 aaggacttgg tttttttgtt acgacatttt gaaaaggctg tccgtaatcc tctggctcat
    15001 ttgattaagc cttttgatga agaggaactg catcgcacca ctcatttttc ttctcaggct
    15061 tttttggaaa acattatcac cttggcgact ttttctggtg taatctaccg atgtgagcct
    15121 ttttactttg atgacatgaa tgccattatt aaaaaggagt tgagcctttg gagacaatct
    15181 attgtctgat atttatcaaa aaacacgata acttgaccga tacaggtctt actaccgtgt
    15241 ttttttagta tgacgattga aaaagaaatt aatcaaaggt tacttcttcg agaaggtatt
    15301 cgataaaacg ttcccccatt ttggacaagt tggctttttc atgcttgata aaaacaatgt
    15361 caatttcgtc agggacatct agcgggatag ccacaatctg gtcaccattt agattgctat
    15421 ttagaatacc actggcaacg gtgtagccat ctaaaccaat cattaagtta aagagggtgg
    15481 cacggtcact gaccacaatt gatttgctgt ggggcatctg ggacatcatc tcttctgaaa
    15541 aataaaagga gttgtgaatc ccttggtcat agctcaggta aggaaaatcg ctcaagtcgt
    15601 ccatgcttaa taggctttta gttgctagag gatttgattt gctgacaaaa atatgaggct
    15661 gtgccttaaa taatggagag gcagtcaaat gattgtcatc aaataatttg gtcaagacat
    15721 ctcggttata gtcgttgata aagagaacac caatttcaga tcgaaagttt ttgacatcat
    15781 caatgatttc ccaagttctt gtctcgcgca aaaagagttc ataccgagtc atgtcggtcc
    15841 gcttgaggag tgagacaaat gcattgacta cgaaggcata atgttgagat gaaacgctaa
    15901 agagctctcg gccagtattg tggtttttat agcggtcttc taacagtgat gtttgctcta
    15961 taatttgtcg agcataagat aaaaattcca ccccatcttt tgtcaaggtg atccctttag
    16021 gatttcggtt gaaaatggta atgcccatct ccatttccaa atccttgacc gcattggata
    16081 gacttggttg tgtgataaat aattgcttag cagcttcatt catagagccg cactcaacaa
    16141 ttttgataat ataatgcagt tgttgaattc tcataagtac agtctagctc aaaaaaaata
    16201 aagacgcaag cacaaacgtc atcatgggtt tagaactttg aaaaagcgct ggagtctttt
    16261 ctcaatatgg cctaggataa atatgattca attttgagag ttgaatctat caatttcatt
    16321 gcccttttat ttttcttgtg ttatattaat agtattaaca aataggtatt tttctaatca
    16381 aagggtggtg gtcgtgtgaa tgttactgaa caaaatagtc atcaaatctt aatccaaaag
    16441 ttattggtca gtatccacta tttgactctt tttcgagatg aactgaagct tgtagaacga
    16501 actccttcta tacttggagg ggaatttcca gctcatttag tacagtctga gttgggagat
    16561 attgttgcgg ccattgatac cttggatatg cagcaacgct tgattgagtc taccttttgg
    16621 tatgaagaat cagcttttaa gttgatgaac aaaactttgg atattgtcga taattggatt
    16681 aaaggagtgg atcatctgat agatttatgc cagtccaaag aagtctttca aattattatt
    16741 ggagataaac gcattcgagt ttttggggtc ttaagtgatg ttttttcatc tttaaaagtg
    16801 agtgctttgt cacttaagga agctcctatt ccggatgtgc tctatgaaca tatccagagg
    16861 gttaatcttg aagaagaaac ttttataaaa tattacgaaa gccctaaggt atccacaggt
    16921 gagtttgaat aaatgattgg gtaaaaatga taaaatgagt tgacgtaagt atacaaaaaa
    16981 agatatagta ggaaaaatgt gttcaaataa caaaaagttt tgacatcttg ttttaaaaaa
    17041 gctataatag tttaaattta gacaccttta agtgagtcca gagaggcaaa caaggtatac
    17101 aagataaaaa aagggaattc ccttttagtt tgctgtagcc tcgcttcttt ggtagcgagg
    17161 ctttttggtg cttaatgaga tattgacaca ttatagaaag gataagttat gaaagaagaa
    17221 cgcccaatta ttgctttaga cttttcatca tttgaggaga ctaaagcatt tttagactta
    17281 tttccagcag aagaaaagct atacgtgaaa attggtatgg aattatatta tgcgcaagga
    17341 ccagatattg ttcggtctat caaatcgtta gggcataatg tatttttgga tttaaaatta
    17401 catgatattc caaatactgt tcgtgctgct atggcagttc ttaaagaatt agatattgat
    17461 atggcaactg ttcatgcagc tggtggtgta gagatgctaa aagcagctcg agaaggacta
    17521 ggccaaggcc ctaccttaat tgcggtaacg cagctaactt caaccagtga agaccaaatg
    17581 cgtggtgatc aaaatattca aacgagtctt ttagagtctg ttttgcatta cagcaagggg
    17641 gcagctaaag ctcagctaga tggggtggtt tgttcggcac aagaagtaga agctatcaag
    17701 gcggtgacgc ctacgggatt tacttgctta actcctggca ttcgtcctaa aggcagtaat
    17761 attggcgatc aaaaacgagt gatgactcca aaccaagcaa gacgcattgg aagtgattat
    17821 attgtggtag ggcgaccaat tacccaggca aaagacccag tggctgctta ccaagccata
    17881 aaagctgagt gggcaggcta acagataaga ttaggaaacc aacacttgtc tgttaaagaa
    17941 gaaaaaggag aataagaaat gacactagca agccaaattg caactcaatt acttgatatt
    18001 aaagctgttt atttaaagcc tgaagatcct tttacgtggg catctggcat taaatcacct
    18061 atttacactg ataatcgtgt caccctttct tatcctaaga ctcgtgattt aattgagaat
    18121 gggtttgtgg aaactatcag ggctcatttc ccagaagttg aggtcatcgc tggtacagct
    18181 acagcaggta ttcctcacgg tgccattata gcagataaaa tgactcttcc ttttgtttat
    18241 attcgcagta agccaaaaga tcatggagca ggcaaccaga ttgaggggcg tgtgcttaaa
    18301 ggccaaaaaa tggttatcat tgaagatttg atttcaacag gtggttcggt actagatgca
    18361 gccgcagcag ccagtcgtga gggagctgac gttctgggag ttgttgcgat tttcacttat
    18421 gagttaccaa aagctagtca gaattttaaa gaagctggta tcaagttgat tacgctttct
    18481 aattatactg agctaattgc agttgcaaag ttgcaaggct atattactaa tgatggttta
    18541 catttactta aaaaatttaa agaagaccag gtaaactggc aacaataagg aactatcagc
    18601 caggtttatt tttaatgaaa aaatctcttt agccccaatt caaaatgtta tgttttgatt
    18661 gttttgtcta cattccttac acatcacatt ctaatttcta accttttaat ggtggttttc
    18721 ttttatttgt gttttaataa aaaagaatgt tttaggattc atatcttaga aaggaagagt
    18781 agctatgact tatcaagatg cgacggctat ggctattgct gttcagactg gtcagaccac
    18841 accactagaa ttagtaaccc aggctattta taaggctaaa aagttgaacc ctaccttaaa
    18901 tgctattacc tcagaacgct ttgaagcagc cctagaagaa gccaaacaaa gggatttttc
    18961 aggtctgcct tttgctggtg tgcctctttt tttaaaagat ttgggacaag aattaaaagg
    19021 tcactcatca acctcaggtt ccagattgtt taaagagtat caagcaacta aaacggattt
    19081 atttgtgaaa agattagaag ctttaggctt tattatttta gggcgctcca acacgcctga
    19141 atttggcttt aaaaatatta gcgatagcag tttgcacgga ccagtgaatt taccaaagga
    19201 taatacacga aatgctggtg gctcatctgg gggagctgct gctctagtgt catcaggaat
    19261 tagtgcgcta gcaactgcta gtgatggtgg tggttctatt cgaattccag cctcgtttaa
    19321 tggcttaatt gggctcaaac ctagccgtgg gcgcatgcct gtcggacctg gttcttatcg
    19381 aagctggcaa ggagcctcag ttcattttgc cttgaccaaa tccgttagag atactagaaa
    19441 tctactctac tatttacaga tggaacaaat ggaaagcccc ttccccctag ccaccttaac
    19501 aaaagatagc atttatcaat cgctacaacg tcccttgaca attgcttttt atcaacggtt
    19561 aagtgacggt agtccagtat ctttagatac tgcaaaagct ttaaaacaag cagtaacttg
    19621 gctaagagaa caagggcatc agctagttga attggaagag tttcctgtaa atatgacaga
    19681 agtgattcgt cattattata ttatgaatag tgtggaaacg gctgctatgt ttgctgatat
    19741 tgaagacact tttggacgtc cgatgaccaa agacgatatg gaaaccatga cctgggctat
    19801 ttaccaatca ggtaaagaca tcccagcttg gcgttactca caggtccttc aaaaatggga
    19861 tacgtacagt gcaaccatgg ctagttttca tgagacttat gacctgttgt tgacgttcac
    19921 aaccaacaca ccagctccta agcacggaga acttgtccca gattcgaaac tcatggctaa
    19981 cctggctcaa gctgaaattt tcagcagtga agagcaattc aatttggtcg aaaccatgtt
    20041 tggtaagagt ctggctatta atccttacac agctctgcct aatctaactg gccagccagc
    20101 tattagttta cctacttacg aaactaagga agggctccca atgggcattc aactaattgc
    20161 agccaaaggt agagaggacc tattattagg aattgcagag cagtttgagg cagcaggatt
    20221 attgaagatt cctcaataat aatcttataa aacagtttaa ctattataga ttaacttttt
    20281 aaagagattg agcgctcact gataacacaa cttaatcaaa atgttatact attcttatct
    20341 taataaagga gttactatga agaaatcagt tactttactg tctatcggac ttgccagcct
    20401 tttattggca gcatgtgcgc cacataaatc tcaaaaatca agttgggaca ctatcaaaga
    20461 aaaaggggtg ttaaaagtag ctaccccagg aacctatcag ccaacttctt tttacaacga
    20521 taataatgag ttagtaggtt acgaagtaga tatggtcaaa gaaatcggta aacgacttaa
    20581 cattaaagtc aagtttgttg aaacaggatt tgaccaagcg tttacctcag ttgatagtgg
    20641 tcgagtggat atttctttga acaactttga cattacccca aaacgtcaga aaaaatacaa
    20701 tatctctacg ccttataaat acggggtagg aggcatgatt gtccgtgctg atggcagctc
    20761 aaacatggct aaaaaagatc ttagcgactg gaaaggaaaa aaagcagctg gtgcttctgg
    20821 aacagaatac atgaaagtag cgcaaaaaca gggagccgaa ctggtgacct acgataatgt
    20881 tacaggagat gtttatctaa acgatgtggc taacggtcga acagatttca tcccaaatga
    20941 ttacccagct caaaaattat ttgtggatta catgttatct caaaatccaa atctaaatgt
    21001 caaaatgagc gatgttcagt acaacccaac cgaacaagga attgttatga acaaaaaaga
    21061 cgatagcctc aagaaaaaaa tagatgctgt tattaaagac atgataaaag atggtagctt
    21121 gaagaaaata tctgaaacct actatgctgg tcaagatttg acaaaacctt ttggcaaaga
    21181 caaaaaaatt cccgtcattg atacgaaaga cgttaactaa tacttgatgt taaaggagtc
    21241 ctaaccacat gattaatatc ccattaatga aagatagttt aggatttgtg ttatcgggat
    21301 taccttatac ccttggtatt tcgttgctca gtttttttac gggtctgttt ttaggtttag
    21361 gcctagccct tctgggaagg tcacgtcagc cgttgattca ttatcttgtt agagcgtaca
    21421 tctctattat gcgaggtgtg ccgatgatcg tggtgctctt tgttctttat ttcgggttgc
    21481 cttattatgg tttagaattg ccagctttac tttgcgctta tcttggtttt tctatggtta
    21541 gcgctgccta tatttctgaa gtttttcgct cttctataga agctattgat aagggacaat
    21601 gggaagcagc taaggcttta gggttgccat atgctcttat ggttaagaaa attattcttc
    21661 ctcaagcctt tcgaattgca gttcctcctc taggcaatgt cattattgat atggttaaaa
    21721 gttcgtcgct agctgccatg attaccgtac cagatatttt tcaaaatgcc aaaattatcg
    21781 gtggtaggga gtgggactac atgtccatgt acattttagt agcctttatc tattggatta
    21841 ttgctttttt gttagaacgt taccaagaat tcttagaaaa taagctagca cttgtttaat
    21901 atcctgtaaa aaacgaatat taaccctgga aatatcatat tttcagggtc tttctattta
    21961 aaatgtggta aactagatag aaaaggacat cgtatttaac ttagaaactg acgtgattag
    22021 aaaggaatct tatggctcat tcaatttggc atgagaaaat caaatcattt ttgccggagc
    22081 attactacgg tcgcatcaat cactttttag atgaagccta tgcttccggt cttgtctatc
    22141 ctccacgaga aaatgtcttt aaagccttac aagtcactcc tttggaagaa accaaagtgt
    22201 tgattttagg acaagaccct tatcatggcc ccaaacaggc ccagggctta tcattttcag
    22261 ttccagaaga gatttctgct ccgccatccc ttattaatat tttaaaagaa ttagcagatg
    22321 acattggtcc tcgtgaccat catgatttaa gcacttgggc tagtcaaggg gttctacttt
    22381 tgaatgcttg cttaacagtg ccagcaggcc aggctaatgg gcatgcaggc ttaatatggg
    22441 agccatttac agacgctgtt attaaagtgc tgaatgagaa agacagccct gtagttttca
    22501 ttttgtgggg agcctatgca aggaagaaaa aagccttcat tactaatcca aagcaccaca
    22561 tcatcgagag ccctcatcca agccctttgt catcttatcg tggctttttt ggcagcaaac
    22621 ccttttcaag aaccaacgct attttagaaa aagagggcat gactggcgta gattggctaa
    22681 aataagccag ccatttcaac taaatagctt aagctagaca ttttgatacc tttaataagt
    22741 gaaatgagtg cagtagattt ttcctattaa agaacgtaag gtcttatggc taaaacagat
    22801 aaataaagga gaaaacatga tactcatcaa aaatggacgc gttatggacc cgaaatcgca
    22861 gagagatcaa gtggcagatg tcttgattga tggtaaacag attgtaaaga tagcttcagc
    22921 tattgaatgc caagaagctc aagtgattga tgctagtggt cttattgttg ctccgggttt
    22981 ggtcgatatt catgtgcatt ttagagaacc cggtcaaacg cacaaagaag atattcacac
    23041 gggagccttg gcagcagcag caggtggtgt gactacggtt gtcatgatgg ctaataccaa
    23101 tcctgtcatt tcagatgtcg aaactttaca ggaagtgcta gctagcgcag ctaaagaaaa
    23161 gattcatatt tacaccaatg ccagtgtcac ccaagccttt aatggaaaag acgtgactga
    23221 ttttaaagct ttgttggaag caggagcagt aagcttttca gatgatggta ttcccttaga
    23281 aagttctaaa gttttaaaag aagcctttga tttggctaat gccaaccaaa ctttcatttc
    23341 tttgcatgag gaagatcctc agttaaatgg ggttcttggt tttaatgaag gtattgctga
    23401 ggagcatttt catttttgtg gggcaactgg tgtagcagaa tatagtatga ttgcaagaga
    23461 tgtcatgatt gcttatgaca ggcaagctca tgttcatatc caacatttat ctaaagcaga
    23521 atcggttcaa gtagtggctt ttgctcagca gttgggtgct aaggtaactg ctgaagtgtc
    23581 cccacaacat ttttcaacaa ctgaagatct cttattgacc gcaggtacca gcgccaagat
    23641 gaatcctccc cttcgtacac aaagagatcg cttagctgtc atagaaggct tgaaatcggg
    23701 tgttatcaca gtcattgcca ctgatcatgc tcctcatcac aaggatgaaa aagctgttga
    23761 tgatatgact aaagccccat ctggtatgac aggacttgaa acttctttgt cattaggttt
    23821 gacgcatttg gttgaaccag gtcatcttac acttatgtca ctattagaaa aaatgacgct
    23881 taatccagct ttgctttatg gttttgatgc gggttatttg gcagaaaatg gtccagcaga
    23941 tttggttatt tttgcagaca agcaagaacg tctgatcact gagaattttg cttctaaagc
    24001 tagtaattcc ccatttattg gtaacaaact caaaggtgtc gtgaaataca ctattgcaga
    24061 cggagaggtt gtttacccta attaacaaat gagttaaaac aaaaaagctt gactttcaga
    24121 ggaagtcagg cttttagtaa atttattttt taggcacttg tttgcttaaa tttagccccc
    24181 aaggtattag attttcagta tgatgtttga tacgactaat gttatctttg tgtcttataa
    24241 taataatgaa cgcaagtaat atcacaataa aagttaaaaa gtagtcataa tttggtaaaa
    24301 gaaaatgaat ggcaggaaat gttaaaacag ataacacacc aacgatagct gaaaccacac
    24361 tagctaaaga tatcatgcta aataaataga gaactaaaac aaagatagat gctaaaaaaa
    24421 agagatataa cggagcaaag cctagcaata caccagcact tgttgctacg gccttaccac
    24481 ctttaaagtt ggcaaaaata ggaaaagtat gccctaaaac tgcgaaaaag ccgatagcaa
    24541 tggatgaaat tgaagtcata ccaaaaataa ttggtaacaa tattgaaagt gtccctttaa
    24601 acatatcaat agctaaggta gctgttcctg ccttgacacc taaaatccga aaagtatttg
    24661 tggttccagt atttcctgat ccatgctctc gtaagttgat gtggtaaaag tactgtccaa
    24721 tccatagtcc agttggaata gaaccaagta aataggcaat ggtaataaaa agtagtaatt
    24781 tcataatcct tattataaca tattcataga ttggagaact agatctggaa aagaattcgg
    24841 aaaaaattag caaattattt tgcaaaattg gtaaaaaact tgtaagataa aaaagatgaa
    24901 actgtctgga ggtcggtgtt gactaagaaa gaaattacaa ttaataatta taatgacgat
    24961 gctatccaag tcctagaagg gttagatgct gttcgcaagc gtccagggat gtatatcggt
    25021 tcaacagatg ctacgggatt gcaccacctg atttgggaaa ttgttgataa tgctgtcgat
    25081 gaggccttgt ctggttttgg agatgatatt aaggttgtta tcaataaaga tggctcggtc
    25141 agtgtggcag atagcggacg tggaatgcca acaggccagc atgccatggg gattcccacc
    25201 gttcaagtta tttttacgat tcttcatgca ggtggtaaat ttggtcaggg tggctacaaa
    25261 acgtcaggtg gtttgcacgg tgttggctcc tctgttgtca atgctttgtc tgcctggtta
    25321 gaagtcgaaa tcacaagaga cgggtcagtg tatcgtcagc gctttgaaaa tggggggaaa
    25381 cctgttacaa cccttaaaaa agttggcaca gctcctaagt ctaaatcagg aacggttgta
    25441 acctttatgc cagatgataa gattttttca actattgact ttaagttcaa taccatttca
    25501 gaacgattga aagaatctgc ttttcttttg aaaaatgtca agatgagctt gacagatctt
    25561 cgtggagatg acccgattat tgaagagttt cattatgaaa atggggttca agatttcgtc
    25621 gaatacctca atgaagataa ggaaaccttg acacctgtta tttacatgga aggtcaagac
    25681 caagactttc aagtcgaggt tgctttgcag tataacgatg gtttctccga caatatctta
    25741 tcctttgtaa acaatgtgcg caccaaagat ggtggaagcc atgaaacggg actaaagtca
    25801 gctattacca aagcgatgaa tgactatgct cgtaaaacca atctcttaaa agaaaaggat
    25861 aaaaatctag agggctcaga ttatcgagaa ggactctcag cagtattatc tatcttagtt
    25921 cctgagcagc acttgcaatt tgaaggacag accaaagaca aattgggaag tcccttagcg
    25981 agacctattg tagagagcat tgtttctgaa aaattaacct tctttttact cgaaaatgga
    26041 gaagtagctt ctcatctagt tcgcaaagcc attaaagcta gagatgctcg cgaagctgct
    26101 cgaaaagcgc gtgatgactc acgtaatggt aagaaaaaca aaaaagacaa aggcttgttg
    26161 tcgggaaaat taaccccagc ccagtccaaa aatgccaaga aaaatgaatt gtatctggtc
    26221 gaaggagatt ctgcgggagg ttcagccaaa caaggacgag accgcaaatt tcaggctatt
    26281 ttaccattac gtggcaaagt tttaaatacc gaaaaagcta agatggctga catcttgaaa
    26341 aatgaagaaa ttaacactat ggtttatacc attggagctg gagtgggagc tgactttaat
    26401 ctcgaggata tcaactatga taagattatt atcatgaccg atgccgatac cgatggtgcc
    26461 cacattcaaa ccctcttatt gaccttcttt taccgttata tgcgaccatt agtagaaaca
    26521 ggtcacgttt atattgcgct tcccccgctt tataaaatgt caaaaggtaa aggtaaaaca
    26581 gagaaagtgt cctacgcttg gacagatggt gaattagaag atttacgtaa ggaatttggt
    26641 aaaggagcca ttcttcaacg ctataaaggg ctaggtgaaa tgaacgccaa ccaattgtgg
    26701 gaaaccacca tggatcctga aaccagaacc cttattcgtg ttactattga tgatttagca
    26761 agagcagaac gacgcgtttc tgttttgatg ggtgacaaag ccgctccacg ccgtcagtgg
    26821 atcgaggaca acgtcaagtt taccttagaa gaaaatacgg tgttttagtc atacaagttt
    26881 ctcacagata attacaagtg ctaaagacga ttgtttttta ggtaattaat aaataatgaa
    26941 aaagaaagct atttgaatat gtcaaacatt caaaacatgt cccttgagga tattatggga
    27001 gaacgcttcg gccgttattc caagtatatt attcaggaac gggcacttcc tgatattcga
    27061 gatggattga aacccgttca gcgccgcatt ctttattcga tgaataagga tggtaatact
    27121 tttgaaaaag gttaccgtaa atcagccaaa tcagttggta atatcatggg gaatttccac
    27181 ccgcatgggg attcctctat ttatgatgcc atggtacgga tgagtcaaga ttggaagaac
    27241 cgtgaaattc ttgtggaaat gcacggaaat aatggttcaa tggatggcga tccgcctgcg
    27301 gctatgcgtt atacagaagt tcgcttgtct gaaattgcgg gttatcttct tcaagacatt
    27361 gagaaaaata cggtctcttt tgcgtggaac tttgatgaca cagaaaaaga acccaccgtt
    27421 ttaccagcag cttttcctaa cttacttgtc aatgggtctt ctggtatttc cgcaggttat
    27481 gcgacagata ttccaccgca caatttgtca gaagtgattg atgccgttgt ttacatgatt
    27541 gaccatccca aggctagctt agagaaatta atggagtttt tgcctgggcc agatttcccg
    27601 acaggaggca ttatccaagg agctgacgaa atcaaaaaag cctacgaaac aggtaaggga
    27661 cgtgtcgttg ttcgctctag gacggaaatt gaggaactta aaggtggtaa acaacaaatt
    27721 attgtcactg agattcctta tgaagttaac aaagcagtct tggtcaaaaa gattgacgat
    27781 gttcgtgtta acaataaagt cccaggcatc gtagaagtac gtgatgaatc tgatcgcaca
    27841 ggtcttcgca tagctattga gttgaaaaaa gatgcagata gccaaaccat tctaaattat
    27901 ttgttgaaat acacagacct tcaagttaat tataatttca atatggttgc tattgatcac
    27961 tttacaccac gccaagtagg tcttcaaaaa atcttatcaa gctatatcag ccaccgcaaa
    28021 gatattatta ttgagcggtc taaattcgat aaagccaaag ctgaaaaacg cctccacatt
    28081 gttgaaggat tgattcgtgt cttgtccatc ttagatgaga ttattgcttt gattagatcg
    28141 tctgacaata aggctgatgc taaagaaaat ctgaaagtca gctatgattt ctctgaggaa
    28201 caagcagaag cgattgtaac cttgcagctt tatcgtttaa ctaataccga tattgttact
    28261 ctccaaaatg aagaaaatga tttaagagac ttaatcacga ccctttccgc tattatcggt
    28321 gacgaagcaa ccatgtataa cgtcatgaaa cgtgaattaa gagaggtgaa aaagaaattc
    28381 gccaatcctc gtttatcaga gttacaagcg gaaagtcaaa tcattgagat tgacactgcc
    28441 agcttgattg cagaggaaga aacttttgtt agtgtgacac ggggcggata cctcaaaaga
    28501 accagcccac gatccttcaa tgcgtctagt ttagaagaag ttggcaagag agatgatgat
    28561 gaactcatct tcgttaaaca ggccaaaaca acagaacacc ttttgttgtt tacaacttta
    28621 ggcaatgtca tttaccgacc aatccatgaa ttgaccgatt tacgttggaa ggatatcggt
    28681 gaacatttat cacaaaccat ttcaaacttc gcgacagaag aagagattct ctacgctgat
    28741 attgtgactt cctttgacca gggcttgtat gtggctgtca cacaaaatgg ttttatcaaa
    28801 cgctttgatc gtaaagaact aagtccttgg cgaacttata aatctaaatc aaccaaatat
    28861 gtgaagctaa aggatgacaa agaccgcgtg gttaccttgt caccagttat tatggaagac
    28921 ctcctattag tgactaaaaa tggttatgct ttgcgattct ccagtcagga agtgcctatt
    28981 caagggttga aatctgctgg tgttaaaggc attaacttga aaaatgatga cagccttgcc
    29041 tcagcctttg ctgtgacaag taactctttc tttgtcttaa ctcagagggg ttctctcaaa
    29101 cggatggctg tcgatgatat tcctcagaca agtcgtgcca atcgtggact attggtccta
    29161 cgagagttaa aaaccaaacc tcatagagtt tttctggccg gaggcgttca atcagatact
    29221 tcagctgagc agtttgattt gttcactgat atacctgaag aagaaactaa tcaacaaatg
    29281 cttgaagtca ttagtaagac tggtcaaacc tacgagattg ctttagaaac gctttcgtta
    29341 tcggaaagaa ccagcaatgg ctcctttatt tcagacacta tttcggatca agaagtactg
    29401 gtagctagaa cacgttaaaa agagtgaaaa ctctttttaa ttttatggta aatttagaat
    29461 attaatgcaa aagaatagaa taaacttgaa aattattgaa aaaaagttac aatagaaaaa
    29521 agcagaaaag aggtacgatg atgacaatag caattgattg ggacaaccta ggatttgaat
    29581 atcataagtt gccatttcgt tacatttctt attacaaaaa tggtcaatgg gataaaggtc
    29641 aattaacaga agatgccacc ttacatatct cagaaagcgc tccagcgctt cattatggac
    29701 aacaagcttt tgaaggttta aaggcttatc gcaccaaaga tggctctatt caactattta
    29761 gaccagaccg taatgcagcg cgtttacaag ccacagcaga ccgcttgttg atgccacaag
    29821 tatcaacaga gcaatttatt gatgcagcta agcaagtggt taaagccaat gaagactttg
    29881 taccacctta cggaacaggt gcaacgcttt acctgagacc gttattaatt ggagttggag
    29941 atattattgg ggttaaacca gccgaagaat atattttcac tatttttgcc atgccagtag
    30001 gaaactattt caaaggtgga cttgctccaa ctaattttat tgtttctgaa gcgtttgatc
    30061 gcgccgctcc ttacggaaca ggtgctgcta aggtgggagg aaactatgca ggaagtttgc
    30121 taccaggtaa ggccgctaaa tcagcaggct tttctgatgt gatttactta gatccagcaa
    30181 cccatactaa aattgaagaa gtcggagctg caaacttttt tggcattact gcaaataatg
    30241 aatttgttac accacttagt ccatccatct tgccatctat tacgaagtat tcactcttac
    30301 aactagctga agaaagactt ggtatgacag taattgaggg tgatgttcca attaatgaat
    30361 tggataaatt tgtggaagca ggagcttgtg gaacagcagc tgttatctct ccaattggcg
    30421 gtatccagta caaggataac ttacatgtct tttacagtga aacagaagtt ggtcctgtga
    30481 cacgccgttt atacgatgag ttggtcggca ttcaatttgg ggatattgaa gcaccagaag
    30541 gttggattgt aaaagtagat taaaatagag cttgctcttg caagcttttt tgattttgtg
    30601 taaaatagac aaagtgaggt aaagtgatga gtaaaaaaga taaaaaaatt gaaatccaac
    30661 tgattgatca caaagttatg gttaatgaga ctaagattga tggctatcaa ttacaaattg
    30721 gtaaacgtgt ggttggagaa attgcagaac ttgatgagaa atttgctgtc ttaaaaaatg
    30781 atggagtaga ttgcttcttc aaaacgctcg aacaagcagt tgaaaatatc attgaaaact
    30841 acaatttgaa ccattaaaat tagacaaaaa cacttgccag cttacaaaaa ctatgataga
    30901 atagtttttg ttgttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
    30961 ctccttcggg ttcgggggtt cgaatccctc tctttccatt tcggaaacta atctaattag
    31021 aaaattagtt ttctgtaaaa aaatattttt ggggtatagc caagcggtaa ggcaagggac
    31081 tttgactccc tcatgcgttg gttcgaatcc agctacccca gtcagaggta tcaggtgctc
    31141 cctgagaccg tcaaagataa gagttgttgt cgttgcgggt taccttgaga aaatatattg
    31201 ttatcaaaag ctagcattgg ctagcttttg ttggaggatt ttttagaatg aatgaatttg
    31261 aagatttgct aaacagtgtt agcgaagtga accctggtga tgttgtcact gcggaagttt
    31321 taactgttga taacggtcaa gcaaacgttg ttatcgaagg aacaggtgtt gaaggtgtct
    31381 tgacacttcg tgaattgact aacgaccgcg atgctgatat taacgacttt gttaaagctg
    31441 gcgacacagt tgaagtactt gttcttcgtc aagtagtagg taaagatact gatacagtta
    31501 ctttcctagt atctaaaaaa cgtttggaag ctcgtaaagc ctgggacaaa cttgttggtc
    31561 gtgaaggcga agttgttact gttaaaggta cccgtgctgt taaaggtggt ctttcagttg
    31621 aatttgaagg acttcgtgga tttatccctg cttcaatgat tgacactcgt tttgttcgca
    31681 acactgaaaa atttgttgga caagagtttg atgctaaaat caaagaagtt gatgcagcag
    31741 aaaaccgttt catcctatca cgtcgtgaag ttatcgaaga ggccgctaaa gaagctcgtg
    31801 ctgaagtgtt ctctaagatt tcagaaggtg cagtcgttac aggtactgta gcgcgtttaa
    31861 caagttttgg tgctttcatt gaccttggtg gtgttgacgg acttgttcac gtgactgaat
    31921 tgtctcacga acgtaatgtg tcacctaaat cagttgtttc agttggtgaa gaagttgaag
    31981 ttaaagttct ttcaattgac gaagaagctg gtcgtgtgtc actttcactt aaagcaacaa
    32041 cacctggacc atgggacggc gttgaacaaa aacttgctca aggtgatgtt gttgaaggta
    32101 aagtaaaacg cttgactgac ttcggtgctt ttgttgaagt attaccaggt attgatggac
    32161 ttgttcatat ttcacaaatt tcacacaaac gtgttgaaaa tccaaaagat gtactttctg
    32221 taggacaaga agtaacagtt aaagttcttg aagtgaatgc agctgatgag cgcgtatcat
    32281 tatcaatcaa agctcttgaa gaacgcccag cgcaagctga aggagacaac aaagaagaaa
    32341 aacgtcaatc acgcccacgt cgtccaaaac gtgaatcaag acgtgactac gaactcccag
    32401 aaacacaaac tggattctca atggctgatc ttttcggtga tattgaattg taataaatct
    32461 aaaaagttga ggttttcctc aactttttat tgtcttctgg ttagaaaagt tatttcatat
    32521 tatttcattt tatgatatac tataagggta ttgacaaagt tgtgaccacc tttagtgtaa
    32581 tggatatcac gtaagattcc ggttcttgag atgggggttc gattccctca aggtggatag
    32641 aaatcatata aaaaagccct atttgatagg ctttttttgt ttcttttcca aaatttgtcc
    32701 aaaattatct agaagagttg acgaaccttt tcaaaatcat tatttttctg accttgaaaa
    32761 cgatgagtat aggttttaaa tatctctgta atgccacagc ctgaatttta tttgactcag
    32821 attcataaga ttgtaagtaa tcaaggttaa ttattgatga gatggtgaaa ccatttttag
    32881 caagtgctat taaagcattt agtgattttt cgaaacgttt taaaatttaa gaagagtttt
    32941 acctaaaaaa ctagctgtgt catctgtcta agcacagtta gttttttagt attagatttt
    33001 taaagaagaa acgtctcaat cttaattgga taatccttat atttggattt taatatagta
    33061 gctacttctt gatatagtat ccgaatctgc gctctttttt caggcatgtt aaaaccaaca
    33121 taatggaatt gtgattcaat agttacaaat aaatcatgga acaggtgatt catagtttct
    33181 agtttatggc aaagcagtcg atcttcttga atgaatgttg ggggattttg atcttctccc
    33241 caataagcat aaacacgtga caacggataa gtcccatatt ctaaacaaag ttcataagtc
    33301 attttggcct ccttgtttta tcttagcatt ttctaaataa agcttctaat gatctgctta
    33361 aaggagtaat ggattgcatc tcatctcatc aaaaataaat tgagatctat tttgtgaaaa
    33421 aaaagacaaa caaatgactt gcctagactt gtttttccta gatataatag gaagtaactg
    33481 aataacaatg aaggagaaaa aatgtcagaa aaaatcagag ttttactcta ttataaatat
    33541 gtttcaattg aaaatgcgca agagtacgct gcgaaacatc tagaattttg taaatctatt
    33601 gggcttaaag gtcgtatttt gattgcggat gaggggatta atggaactgt ttctggagat
    33661 tatgaaacaa ctcagaagta tatggattgg gtccacagcg atgagcgttt tgctgatctt
    33721 tggttcaaga ttgacgagga aaatcaacaa gctttccgta aaatgtttgt tcgttataag
    33781 aaagagatcg tgcaccttgg gttagaagac aataactttg atagtgatat taatcctttg
    33841 gaaacaacag gtgagtattt aaatcctaaa caatttaaag aagccttgct tgatgaagat
    33901 actgttgttt tagatacgcg taatgattat gagtatgact taggtcactt ccgtggagca
    33961 attcgtcctg atattcgcaa tttccgtgag ttaccacaat gggtacgtga caacaaagat
    34021 aagtttatgg aaaaacgtgt tgttgtgtac tgtacgggtg gtgttcgctg tgagaaattc
    34081 tcgggttggc tggttcgaga aggctttaaa gatgttggac aattacacgg tggtattgca
    34141 acatatggaa aagatccgga agttcaaggt gaactttggg atggtgcgat gtatgttttt
    34201 gatgatcgta tctcggtgcc aattaatcat gttaatccaa ctgtcattag taaagattat
    34261 tttgatggaa caccttgtga acgttatgtc aattgtgcaa atccgttttg taacaaacaa
    34321 atttttgctt cagaagaaaa cgaaacaaag tatgttcgag gatgctcgcc tgaatgtcgt
    34381 gcacatgaac gtaatcgcta tgtgcaagaa aatggtttat cacgtcaaga atgggcagaa
    34441 cgtttagaag ctattggaga atccttgcca gaatttgtag gtgcctaata tctcaaaaca
    34501 aatcaggaaa ctggtttgtt ttttgtgata cagatgatga gaccaaattg caaagacttt
    34561 gcaacaagat actagtgaac gtggacacca agctcatttt gtcatgcaga gccatcaaca
    34621 gcgaagacgt caacaccaac tctgtctaga accttttcaa aagaattgtg agtttctgta
    34681 ttacgagata gagaaggtaa aactggattc tgaagactgc cttaccatca atcctttggg
    34741 aatggtttaa gctttacagc ttgatgatgg tcaaatcgtc acacaggcag gtattatctt
    34801 gctctttata gcgaaacaaa ccctgaaatc tcagctcatt ccccaagata atcttttggc
    34861 agaaagttga ttcaacgaaa tcatggattt cttaacaggt gattttcccc ttgtttttag
    34921 gccaatgtac aaccctcatc gctacactat ttctcaagac aatcaagcgc ttgaaaaagt
    34981 caaacaagct tcttacaagc ggatggatat tgctatgacg catttagatg gtcttattgg
    35041 ggatagtggg catgtttatc gagatcaaca aaccattgca gatgcttatg cttacgccat
    35101 ggcgctatgg tctcaaaaaa caccaaaatc ttacgagaat tatccgcatc t
//
LOCUS       DAUGUF010000022        32675 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUGUF010000022 DAUGUF010000000
VERSION     DAUGUF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32675
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.022"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            18..98
                     /locus_tag="VIB71_001036"
     tRNA            18..98
                     /locus_tag="VIB71_001036"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VIB71_001037"
     tRNA            105..175
                     /locus_tag="VIB71_001037"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VIB71_001038"
     tRNA            187..259
                     /locus_tag="VIB71_001038"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VIB71_001039"
     tRNA            268..339
                     /locus_tag="VIB71_001039"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VIB71_001040"
     tRNA            359..442
                     /locus_tag="VIB71_001040"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            702..887
                     /locus_tag="VIB71_001041"
     CDS             702..887
                     /locus_tag="VIB71_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822776.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWPEP"
     gene            1525..1833
                     /locus_tag="VIB71_001042"
     CDS             1525..1833
                     /locus_tag="VIB71_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ8822777.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSDVPYCLLSGCAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            1888..2100
                     /locus_tag="VIB71_001043"
     CDS             1888..2100
                     /locus_tag="VIB71_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ8822778.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            2210..2653
                     /locus_tag="VIB71_001044"
     CDS             2210..2653
                     /locus_tag="VIB71_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEQ8822779.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2657..3376
                     /locus_tag="VIB71_001045"
     CDS             2657..3376
                     /locus_tag="VIB71_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822780.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEVETDDEKGGHGHA"
     gene            3369..4184
                     /locus_tag="VIB71_001046"
     CDS             3369..4184
                     /locus_tag="VIB71_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ8822781.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4224..4607)
                     /locus_tag="VIB71_001047"
     CDS             complement(4224..4607)
                     /locus_tag="VIB71_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ8822782.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWESITINQENWDLTPFLKHL"
     gene            complement(4658..5914)
                     /locus_tag="VIB71_001048"
     CDS             complement(4658..5914)
                     /locus_tag="VIB71_001048"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEQ8822783.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6006..8318
                     /locus_tag="VIB71_001049"
     CDS             6006..8318
                     /locus_tag="VIB71_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ8822784.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8582..12148
                     /gene="rpoB"
                     /locus_tag="VIB71_001050"
     CDS             8582..12148
                     /gene="rpoB"
                     /locus_tag="VIB71_001050"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ8822785.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12239..15862
                     /gene="rpoC"
                     /locus_tag="VIB71_001051"
     CDS             12239..15862
                     /gene="rpoC"
                     /locus_tag="VIB71_001051"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEQ8822786.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAE"
     gene            16014..16379
                     /locus_tag="VIB71_001052"
     CDS             16014..16379
                     /locus_tag="VIB71_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEQ8822787.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16472..17410
                     /gene="tadA"
                     /locus_tag="VIB71_001053"
     CDS             16472..17410
                     /gene="tadA"
                     /locus_tag="VIB71_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEQ8822788.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYARLLELGITKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17394..18380
                     /locus_tag="VIB71_001054"
     CDS             17394..18380
                     /locus_tag="VIB71_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEQ8822789.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWSTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGVELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18382..18708
                     /locus_tag="VIB71_001055"
     CDS             18382..18708
                     /locus_tag="VIB71_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEQ8822790.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18683..19111
                     /locus_tag="VIB71_001056"
     CDS             18683..19111
                     /locus_tag="VIB71_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEQ8822791.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19116..19352
                     /locus_tag="VIB71_001057"
     CDS             19116..19352
                     /locus_tag="VIB71_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8822792.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEMTLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19345..19779
                     /locus_tag="VIB71_001058"
     CDS             19345..19779
                     /locus_tag="VIB71_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEQ8822793.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19763..20089
                     /locus_tag="VIB71_001059"
     CDS             19763..20089
                     /locus_tag="VIB71_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ8822794.1"
                     /translation="MPFKTNLKAGVLLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20187..21140
                     /locus_tag="VIB71_001060"
     CDS             20187..21140
                     /locus_tag="VIB71_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8822795.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21199..22395
                     /locus_tag="VIB71_001061"
     CDS             21199..22395
                     /locus_tag="VIB71_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEQ8822796.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22582..22890
                     /locus_tag="VIB71_001062"
     CDS             22582..22890
                     /locus_tag="VIB71_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822797.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLALIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(22973..23743)
                     /locus_tag="VIB71_001063"
     CDS             complement(22973..23743)
                     /locus_tag="VIB71_001063"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEQ8822798.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23791..24858)
                     /gene="pepA"
                     /locus_tag="VIB71_001064"
     CDS             complement(23791..24858)
                     /gene="pepA"
                     /locus_tag="VIB71_001064"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEQ8822799.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRAVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEDAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            25314..25604
                     /locus_tag="VIB71_001065"
     CDS             25314..25604
                     /locus_tag="VIB71_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEQ8822800.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRKRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDK"
     gene            25604..25921
                     /locus_tag="VIB71_001066"
     CDS             25604..25921
                     /locus_tag="VIB71_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEQ8822801.1"
                     /translation="MIRPTSYESLAALVEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWDIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25939..26565
                     /locus_tag="VIB71_001067"
     CDS             25939..26565
                     /locus_tag="VIB71_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEQ8822802.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMVAHLDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            26717..27112
                     /locus_tag="VIB71_001068"
     CDS             26717..27112
                     /locus_tag="VIB71_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ8822803.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLISIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27372..28013)
                     /locus_tag="VIB71_001069"
     CDS             complement(27372..28013)
                     /locus_tag="VIB71_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEQ8822804.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28033..29010)
                     /gene="dusB"
                     /locus_tag="VIB71_001070"
     CDS             complement(28033..29010)
                     /gene="dusB"
                     /locus_tag="VIB71_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEQ8822805.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(28997..29869)
                     /gene="hslO"
                     /locus_tag="VIB71_001071"
     CDS             complement(28997..29869)
                     /gene="hslO"
                     /locus_tag="VIB71_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEQ8822806.1"
                     /translation="MDKIIKSIAQSGSFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSRITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEVARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIINDKA"
     gene            complement(30016..31509)
                     /gene="rofA"
                     /locus_tag="VIB71_001072"
     CDS             complement(30016..31509)
                     /gene="rofA"
                     /locus_tag="VIB71_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEQ8822807.1"
                     /translation="MIEKYLESSIESKCQLVVLFFKTSSLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPDSLSMTIQKRMISCQFTHPSKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNIIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
     gene            31777..>32675
                     /locus_tag="VIB71_001073"
     CDS             31777..>32675
                     /locus_tag="VIB71_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEQ8822808.1"
                     /translation="MNNKMFLNKEAGFLVHTKRKRRFAVTLVGVFFLLLACAGAIGFG
                     QVAYAADEKTVPNFKSPDPDYPWYGYDSYRGIFARYHNLKVNLKGSKEYQAYCFNLTK
                     YFPRPTYSTTNNFYKKIDGSGSAFKSYAANPRVLDENLDKLEKNILNVIYNGYKSNAN
                     GFMNGIEDLNAILVTQNAIWYYSDSAPLNDVNKMWEREVRNGEISESQVTLMREALKK
                     LIDPNLEATAANKIPSGYRLNIFKSENEDYQNLLSAEYVPDDPPKPGDTSEHNPKTPE
                     LDGTPIPEDPKRPDESSEPALPP"
BASE COUNT         9828 a         5870 c         7075 g         9902 t
ORIGIN      
        1 aaaatttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tacaaacctt gttttttgtt
      481 ttgatcttaa gctgtagcta cgtagtacaa tctcttatat tactgataag gtctatttaa
      541 tgcgcaagat ttgtggtatg atgaatatga ttgagtattg atgctttatg ggattaccgg
      601 taaggttttg aaaaaggttt gtcactacta ggtgcttttt tagctataga aagacagtta
      661 tggattgatg tattgtaact aatgttggag gttaatggtg gttgagtttt gagatattta
      721 cactgataat cgggtggaaa ctggttgggt atcgggtaat ggagtgtggt tcttcgttta
      781 agcaaggaga ttatcgtttg gtggttcata tttgcttgtt aaatgttagg gatgagatgc
      841 tgagtcagca aggccatgaa gataaagctg actggccaga gccttgagat gtgacgtttg
      901 gtggaagtcc tttttggtga gatggcacag catatagtaa tattagatcc tgaggaagaa
      961 ttgggacttt cattaggctt gactggggta tgacctcact ttacaattca tttcgatgat
     1021 gggtttgatg atacgttttt agttcaggac tttgtagagt tggagaattt ggttctttat
     1081 gaggaagaag tgcaggtaat tcgttgagac agtcgtgaag atattttagg tatgattgat
     1141 gaaggttcgt tcattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggc
     1201 caatataaag tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt
     1261 atatttgata gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga
     1321 gcttctgtaa aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac
     1381 gatttatcga tggtcatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata
     1441 gatgacaata agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat
     1501 gatgtttata agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc
     1561 gtttacttgg aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct
     1621 gttactatca gagcattaaa tcagttatgg ctccttactc ttagccgaaa agatatgatg
     1681 gatattggta taccgattgg tagtgatgtg ccttattgct tgctttcagg ttgtgcccaa
     1741 gtcactggta aaggtgaagt ggtttgtcgc attttggggc tgttatcgtc ttgggtggtt
     1801 ttggttaaac cagattttgg tatctcgact tgaacatttt ttctagatat taattgtaaa
     1861 atcatttcaa gagtgtctac tactcatttg gttgcggcga ttgaagcggg taactataat
     1921 gatgggatat tgactgaaat gaacaatttg ctggaagata ttttcattgc caagcgaccc
     1981 tttattcaaa aaataaaaga gaaaacactg caagctggtg ctgctactac tttgatgaca
     2041 ggaagtggac cgactgtttt tgctttgtgc cagaccgaaa aacaaactat aatagtttaa
     2101 aaggactttg caaggaagtt tttaaggtga gaatgttgta atattttgtt gggattgctt
     2161 ctttggaagc ttcatgttat aattaactgg ttaatgaaag aggagattta tggggacttt
     2221 agaaaaaaaa cttgataact tagtaaatac tattttatta aaagcagaaa atcagcatga
     2281 gttattattt ggagcttgtc aaagtgacgt taagcttact aatacgcaag aacatatttt
     2341 aatgttacta tctcagcaac gtctcactaa tacagatttg gctaaggcat taaatattag
     2401 tcaggcggca gtaactaagg ctatcaagag tttggtcaaa caagacatgc tagcaggaac
     2461 taaggatacg gttgatgcta gggtgactta ttttgaatta accgagttag ctaagcctat
     2521 tgcgtcagaa catacccatc atcatgatga aaccttaaat gtttacaacc gtttattaca
     2581 aaaattctcc gcgaaagaat tagagattgt agataagttt gtaacagttt ttgctgagga
     2641 attagaaggg taatccatga gatacatatc agtgaaaaat ctctcctttc aatatgaaag
     2701 tgagccagtt ttagaaggga tcacttatca tttagatagt ggagaatttg tcaccatgac
     2761 cggtgaaaat ggcgctgcaa agtcaacctt aataaaagca accttaggaa ttttacaacc
     2821 aaaggctgga cgagttacta ttgctaaaaa aaataaagac ggtaaacaat taaggattgc
     2881 ttacttgccg cagcaagtag ctagctttaa cgctggtttt ccatccaccg tttacgagtt
     2941 tgtcaaatca ggtcgctacc cacgtagtgg ttggtttaga catttgaaca aacacgatga
     3001 agagcatgtg caagcaagct tagaagcagt cggcatgtgg gaaaaccgtc ataagagaat
     3061 tggtagttta tcaggtggtc aaaaacaacg tgtggttatt gcccgtatgt ttgcttctga
     3121 ccctgatatt tttgtgctag acgagccaac aacgggaatg gatagcggta ctactgatac
     3181 cttttatgaa ctgatgcacc acagtgcaca tcaacacggg aaatccgttc tgatgattac
     3241 ccatgaccca gaagaagtga aggcttatgc tgatcggaac attcatttag tcagaaacca
     3301 aaaacttcct tggcgttgtt tcaacattca tgaagttgaa acagatgacg aaaaaggagg
     3361 tcatggtcat gcttgatatt ttatcctatg atttcatgca acgggcggta atggcggtag
     3421 ttgccattag tatttttgct ccgattttag gtattttcct tattttacgt cgtcaaagtt
     3481 tgatgagcga tacccttagt catgtttctt tggctggggt agcgcttggg gtagtccttg
     3541 gtatttcacc aaccatcact actattattg ttgtggtttt agctgctatt ttgttagaat
     3601 acctgcgtgt agtttacaaa cactacatgg agatttcaac ggcgattttg atgtcacttg
     3661 gcttggccct atctctgatt attatgagta agtcgcatag ttcatcaagc atgagtttag
     3721 aacaatacct ttttggatcg atcatcacga ttagtatgga acaagttgtc gccttgtttg
     3781 ctattgctgc gattatttta atcttgaccg ttctcttcat tagaccgatg tacattctga
     3841 cctttgatga agatactgct tttgtagatg gtttgcccgt tcgcttgatg tctgttctat
     3901 tcaatatcgt cactggggtt gctattgctt tgaccattcc agcagcagga gcacttttgg
     3961 tttctaccat tatggtcttg ccagcaagta tcgcaatgag attgggtaaa aactttaaaa
     4021 cagttatctt actgggaatt gtcatcggtt ttagcggtat gttatctggt attttcttat
     4081 cttatttctt tgaaacgcca gctagtgcca ctattaccat gattttcatt agtattttcc
     4141 tcttagttag tctaggtgga atgcttaaaa aacggttatt ttaataagaa aaatcctcac
     4201 atgtttaaca tgtgaggatt tatttataaa tgctttaaaa agggggtaag gtcccaattt
     4261 tcttgattaa tggtgatgct ctcccaaaag ctatcattag ttaaacgagg aatcaaatga
     4321 aggtgaaaat gagtcccctc atccatcaac tccttgtcat tgctgacgct agtgacgcct
     4381 gaaatgggaa ggtgctgctc tagcttagca actagagcgg cttgtaagtc gatgagatca
     4441 tagcgcactt cctttggtag ttgtgtcaga ctagtgtaat ggtctttgga aatcagtaaa
     4501 aggtgcccct tttggatagg atcaatatca aaaacaacct tgaaatattg actttgagtc
     4561 agtagctgat ttgctttgag ctgatggcaa aagatacatt ctgtcatagg tacatctcct
     4621 tatgaaaaaa cgagccagag ctcgtttaat cggttatcta gtaagtgaga acagcgtatt
     4681 ttttcttacc gcggcgaata acggttaatt gatcatcaat tttatcatca ttacttaatt
     4741 ggtaatctaa atcttgaacg cggtctccgt taatgtagat tgctccattt tgcacgtctt
     4801 cacgcgcttg gcgttttgat ggggaaatac ccgcggtgac aagcatgtca acaaggttaa
     4861 ggctgtcttc tgattgaacg tgataatttg gtacattgct caatccttgt tttaattcat
     4921 tagcagaaag atttttgatg tttccagcaa ataactgctc ggtaatgtta agagcttgtt
     4981 tataagcttc ttcgccatga accaaggtaa ccacttcgcg tgccaaggtt ttttgagcga
     5041 gacgctcgtg acgagcggca ttaaattgag tttcaatttc tgcaatctca tctagagata
     5101 agaaggtgaa gattttcaag aaacgcactg catcatcatc catgacattt aaccagaatt
     5161 ggtacatctc gtaaggagac gtcttatcgg catcaagcca gacagcatta ccttctgatt
     5221 taccgaattt tttcccggtt gagtcagtga tgagtggtac agtcatgacg tgcccagttt
     5281 tatcagcctt tttgcggagc aattcagtac cagctgtcat attaccccac tggtcagagc
     5341 cgccaatttg taaggttaca ttatgcttgt cattgagttc gtagaagtcg tagccctgca
     5401 tgatttggta agcaaactca gtgtaagaaa tgcctgtttc aatgcgtttt ttaacagagt
     5461 ctttactcat catgtagtta acggtgaagt atttaccgac atcacggagg aagtcaataa
     5521 agctgatttg cgagaaccag tcgtagttgt tgacaagctc tgctttatta tcaccatttt
     5581 caaaatcaag gaaagtagac aactgccctt taatcttgtc actccactcc aaaactgttt
     5641 ctttggtttg aaggctgcgc tctgcatctt taaaggaagg atcaccaatt aaacctgtgg
     5701 caccacccac aagagcgtaa ggtttgtgcc ctgctagttg caagcgacga gatgttaaga
     5761 tagccactag atggcccaga tgaaggctgt cagcggttgg atcataaccg gtataatagg
     5821 atacttgccc ttctgttaat gctttgacaa gggcttgttc atcagtcgtt tgaaagacca
     5881 agccacgagc tttgagttct tcaaaaatat tcataggctt tctccatttt cattatagtt
     5941 tcgaatcatt atatcaaaaa acgctactgc tatgcaagct ttatcaaagt ttggtataat
     6001 gataaatgag gtattttatg gtgaaatgga acacgaaaca aaagcgtata agtcatcaaa
     6061 gattaggtct cttggatttg gggccggtgc tattacgtac gttgagacta ctgtctaact
     6121 ttttttatat tgttatcttc ctttttggaa tgatgggatt tggtatggca tttgggtatt
     6181 tggctagtca gattgaatct gttaaggtac caagtaaaga aagtttagtc aaacaagttg
     6241 aatcattaac gatgatttcg caaatgaact attctgataa tagtttaatt tctactttag
     6301 atacggattt acttcgaaca ccagtagcta atgatgcgat ttcagagaat atcaaaaaag
     6361 ctattgtatc aacagaagac gaacattttc aagaacataa aggtgtcgtg ccaaaagctg
     6421 tttttcgggc aacattggct tctgtattgg gatttggaga agctagtgga ggttcgacct
     6481 taacacagca attagtcaag caacaagttt tgggagacga tcccacattt aagcgcaagt
     6541 ctaaggagat cgtttacgct cttgccttag agcgttatat gtccaaagac aatatcttat
     6601 gtgattatct taatgtttca ccttttggcc gtaacaacaa gggtcaaaat attgctggtg
     6661 ttgaagaagc tgcgcgtggc atttttggcg tttctgccaa agatttaacg gtgccacagg
     6721 cagcattttt ggcgggtctt ccgcagagtc ctattgttta ctctccttat ttgtcaacgg
     6781 gacaactgaa gtcagaaaag gacatggctt atggcatcaa gcgtcagcaa aatgttctct
     6841 ataacatgta ccgtacaggt gttctgtcta aaaaagaata cgaggactat aaggcttatc
     6901 cgattcaaaa ggattttatt caaccgggaa gtgcaatagt aaataatcac gattaccttt
     6961 attacacggt gttagcggat gctaaaaaag ccatgtatag ctatttgatt aagcgagata
     7021 aggtgtctag tcgtgacttg aaaaatgacg agactaaggc tgcttatgaa gagagagcct
     7081 taacagaatt gcaacagggt ggctatacca tcaccacaac cattaataag cctatttaca
     7141 atgcgatgca gacagcggca gctcagtttg gtggcctgtt agatgatggc actggtacag
     7201 ttcaaatggg aaatgtcttg acagacaatg cgactggtgc tgtgttaggt tttgttggtg
     7261 gtagagatta tgctctgaat caaaataatc atgctttcaa tacagttaga tcgccaggtt
     7321 ctagcattaa accgataatc gcttatggtc ctgctattga tcaaggttta atggggagtg
     7381 ctagcgtttt gtctaattac ccaacaactt actcgagtgg ccaaaaaatc atgcatgctg
     7441 atagtgaagg aacagccatg atgccacttc aagaggccct aaatacttct tggaacatcc
     7501 cagctttttg gacacagaaa ttactgcgtg aaaaaggggt cgatgtcgaa aattatatga
     7561 caaaaatggg ttataagatt gcagactact cgattgaaag tttacctcta gggggcggta
     7621 ttgaagtctc ggttgctcaa caaaccaatg cttaccaaat gctttcaaac aatggcttat
     7681 atcaaaagca atatattgta gataagatta ctgctagcga tggtacagtc gtttacaaac
     7741 atgaaaataa gccaattcgt attttttctg cagcaacagc tacgatttta caagaattgt
     7801 tgagaggtcc gattacttca ggcgctacga ctactttcaa gaaccgtttg gcggctatta
     7861 atccgtggct tgctaatgct gattggattg gtaagaccgg aacaactgag aattatacgg
     7921 atgtttggct agtcctgtct actccaaaag ttaccttagg cggttgggca ggacatgatg
     7981 acaatacctc attagcgcca ttaacaggat ataacaataa ttctaattac cttgcctatt
     8041 tagctaatgc cattaatcag gccgatccca atgttattgg agtagggcaa cgtttcaact
     8101 tagatccagg agtcattaag gcgaatgtct tgaagtcaac aggtttacaa ccaggaactg
     8161 ttaatgtcaa tggacatact ttttctgttg gtggagaaat gaccaccagt ctatggtccc
     8221 aaaaaggacc gggggctatg acttaccgat ttgctattgg tggcacggat gccgattatc
     8281 aaaaagcttg ggggaacttt gggttcagaa aaaattaggt tgccatttat cgataaaaag
     8341 ggtataatag caataactat ttgtcgtcca atctagctga aatattgtcc agttaggaag
     8401 aacagcagtt aaatcacact gataaagtca gatttagctg ctctttttgt gtctattttt
     8461 agaaaagata gggtttgtaa cctatattta aatattctaa aaattaacat ttagggcaaa
     8521 tgataactta gttgcgattt gctgaaacag caaagcttaa atagaagaag gagctaaaaa
     8581 cttggcagga catgaagttc gatacggaaa acaccgtaca cgtcgtagct tttcaagaat
     8641 caaagaagtt cttgatttac caaatttgat tgaaattcaa actgactcat tccaagattt
     8701 cctcgattca ggtttgaaag aagtatttga agatgtactt cctatttcaa actttacgga
     8761 tactatggaa cttgaatttg ttggttacga atttaaagaa cctaaatata cccttgaaga
     8821 agctcgtatc cacgatgcaa gttattctgc accaatcttt gttaccttcc gtttggtcaa
     8881 taaagaaact ggtgagatta aaactcaaga agtcttcttt ggtgatttcc caatcatgac
     8941 ggaaatgggt acctttatta tcaatggtgg tgaacgtatc atcgtttctc agttggtgcg
     9001 ttctccaggt gtttatttca acgataaagt tgataaaaac ggtaaagttg gttacggatc
     9061 aacagtgatt cctaaccgtg gggcttggtt ggaattagag actgactcaa aagacattgc
     9121 ctacactcgt attgaccgta cccgtaagat tccattcaca accttggttc gtgcccttgg
     9181 tttctcaggt gatgatgaaa ttgttgatat ctttggtgaa agcgaccttg ttcgtaatac
     9241 cattgaaaaa gacattcaca aaaatccaag tgattctcgt acagacgaag cccttaaaga
     9301 aatttacgag cgtcttcgtc caggtgagcc aaaaactgca gatagctctc gtagtctttt
     9361 gattgcgcgt ttctttgatg cacgtcgtta cgatttggct gcggttggtc gttacaaagt
     9421 gaacaaaaaa cttaatatca agactcgtct tttgaaccaa atcattgctg aaaaccttgt
     9481 ggatgctgaa actggcgaaa ttttggtaga agctggaact gagatgactc gtagcgtcat
     9541 cgaatccatc gaagaacacc ttgacggtga tttgaacaag tttgtttaca caccaaatga
     9601 ttacgctgtg gttactgaac ctgttgttct tcaaaagttc aaggttgtgt caccaattga
     9661 tcctgatcgt gtagtaacta ttgttggtaa tgccaatcca gatgacaagg ttcgtgcatt
     9721 gacacctgct gatattttgg cagaaatgtc ttacttcttg aaccttgcag aaggtcttgg
     9781 aaaagttgac gatattgacc acttaggtaa ccgtcgtatc cgtgccgttg gtgaattgct
     9841 tgccaaccaa ttccgcatcg gtcttgctcg tatggagcgt aacgttcgtg agcgtatgtc
     9901 tgttcaagac aacgatgtgt taacaccaca acaaatcatc aatatccgtc ctgtcacagc
     9961 agctgtcaaa gaattcttcg gttcgtctca gttgtcacaa ttcatggacc aacacaaccc
    10021 attgtcagag ttgtctcaca aacgtcgttt atctgcctta ggacctggtg gtttgacacg
    10081 tgaccgtgct ggttatgagg ttcgtgacgt gcattacacg cactatggcc gtatgtgtcc
    10141 gattgaaaca cctgaaggac caaacattgg tttgattaac aacttgtctt catttggaca
    10201 tcttaataaa tatggtttca tccaaacacc ttaccgtaag gttgaccgtg cgactggtag
    10261 ggtaactaac gagattgttt ggttgactgc cgacgaagaa gacgaataca cagttgcaca
    10321 ggccaattcg aaactaaacg aagatggcac ttttgctgaa gaaatcgtta tgggtcgtca
    10381 ccaaggtaat aaccaagaat tttctgcaag tgttgttgat ttcgttgacg tttcccctaa
    10441 acaggtagtt gctgttgcga cggcatgtat tcctttcttg gaaaacgatg actccaaccg
    10501 tgccctcatg ggtgccaaca tgcaacgtca ggctgtgcca ttgattgatc caaaagcacc
    10561 atatgttggt actggtatgg aatatcaagc tgcccatgac tcaggcgctg cggtgattgc
    10621 tcagcacaat ggtaaagttg tcttttctga tgctgaaaaa gtggaaatcc gtcgtcaaga
    10681 tggctcactt gatgtttacc acattaccaa attccgtcgt tcaaactcag gaacagccta
    10741 taaccaacgc acccttgtta aagtaggaga cattgttgaa aaaggtgatt tcatcgctga
    10801 tggaccttct atggaaaatg gtgaaatggc tcttggacaa aacccagtcg ttgcttacat
    10861 gacttgggaa ggttataact ttgaggatgc cgttatcatg agtgagcgcc ttgtgaaaga
    10921 agatgtctac acatctgttc acttggaaga attcgaatct gaaacgcgtg atacaaaact
    10981 tggccctgaa gaaatcactc gggaaatccc aaatgttggt gaagaagccc tcaaagacct
    11041 tgacgaaatg ggcattatcc gtatcggtgc tgaggtgaaa gaaggcgaca tcttagtagg
    11101 taaagtcaca cctaaaggtg aaaaagacct ttctgctgaa gaacgtttac ttcacgccat
    11161 ctttggggat aaatcgcgtg aagtgcgtga tacctcactt cgtgtccctc atggtggtga
    11221 tggtattgtt cgtgatgtga aaatctttac acgcgctaac ggcgatgaat tgcaatcagg
    11281 tgttaatatg cttgtgcgtg tttacatcgc tcaaaaacgt aaaatcaagg tcggagataa
    11341 aatggccggt cgtcacggaa acaagggtgt cgtttcacgt attgtaccag ttgaagacat
    11401 gccatacctt ccagacggaa caccagttga catcatgttg aaccctctcg gggtgccatc
    11461 acggatgaat attggtcagg ttatggaact tcaccttggt atggctgctc gtaatcttgg
    11521 cattcacatt gcaacacctg tctttgacgg ggcttcatca gaagaccttt gggacactgt
    11581 tcgtgaagct ggcatggata gcgatgctaa gacggtcctt tatgatggtc gcaccggtga
    11641 accatttgac aaccgtgtat ccgttggtgt catgtatatg atcaaacttc accacatggt
    11701 tgatgataaa cttcatgccc gttctgtagg accatactca cttgttaccc aacagccact
    11761 tggtggtaaa gctcaatttg gtggacaacg ttttggtgag atggaggttt gggcccttga
    11821 agcttatggt gcatcaaatg ttcttcaaga aatcttgacc tacaagtcag atgacgtcac
    11881 aggacgtttg aaagcctatg aagcgattac taaaggtaaa ccaattccaa aaccaggtgt
    11941 accagaatcc ttccgtgttc ttgtaaaaga attgcaatcg cttggtcttg atatgcgtgt
    12001 gcttgacgag gatgataatg aagtggaact tcgtgatctt gatgaaggtg aagacgatga
    12061 tattatgcat gttgacgatc tcgagaaggc acgtgaaaaa caagctcaag aaacccaaga
    12121 agtttctgaa acaactgacg aaaaataagc aatcaattct tattaaataa ttatttactg
    12181 gtctggggca aaggccccag gaactggtaa agtcatcaaa ggcagaaagg taaaactagt
    12241 ggttgacgta aatcgtttta aaagtatgca aatcacatta gcctcaccaa gtaaggtccg
    12301 ttcatggtct tatggtgaag ttaaaaaacc tgaaacaatc aactaccgta cattaaaacc
    12361 agaacgtgaa ggactctttg acgaagtcat ctttggtcca acaaaagact gggaatgtgc
    12421 gtgtggtaag tacaaacgta tccgttataa agggatcgtt tgtgaccgct gtggggttga
    12481 ggtaactcgt gctaaagtac gtcgtgaacg tatgggtcac attgagttaa aagctcctgt
    12541 atcacatatc tggtatttca aagggattcc atctcgtatg ggattgactc ttgatatgag
    12601 tcctcgtgcc cttgaagaag tgatctattt tgcggcttat gtggtcattg atccaaaaga
    12661 tacaccgctt gaaccaaaat cattattaac agaacgtgaa taccgtgaaa aactacaaga
    12721 gtatggtcat gggtcatttg tcgctaagat gggtgctgaa gccattcaag atctcttgaa
    12781 acgtgtggac ttggcagctg aaatcgctga attaaaagaa gagttgaaat ctgcttctgg
    12841 tcaaaaacgg attaaagcag ttcgtcgttt agacgtcctt gatgccttta acaaatctgg
    12901 aaataaacca gaatggatgg ttcttaacat cctgccggtt attccaccag atcttcgtcc
    12961 gatggttcaa ttggatggtg gtcgttttgc ggcatcagac ttgaatgact tgtaccgtcg
    13021 tgtgattaac cgtaacaacc gtttggcacg tttgttagaa cttaatgccc ctggcatcat
    13081 tgttcaaaat gaaaaacgaa tgcttcaaga agccgttgat gctttgattg ataatggtcg
    13141 tcgtggtcgt ccaatcactg gaccaggtag tcgtccattg aaatcattga gccacatgct
    13201 taaaggtaaa caagggcgtt tccgtcaaaa cttgcttggt aaacgtgtag acttctctgg
    13261 acgttccgtt atcgctgttg gtccgaccct taaaatgtat caatgtggtg tcccacgtga
    13321 aatggctatc gagcttttta aaccatttgt aatgcgcgaa attgttgcca aagaatatgc
    13381 tggtaacgtt aaagccgcta aacgtatggt tgaacgtggc gacgaacgca tctgggatat
    13441 cttagaagaa gttatcaaag aacacccagt cctacttaac cgcgcaccga ctcttcacag
    13501 acttggtatt caggcttttg aaccggttct tattgacggt aaggcacttc gtcttcaccc
    13561 acttgtgtgt gaggcctaca atgccgactt cgatggagac caaatggcca tccacgtgcc
    13621 actttcagaa gaagcacaag ctgaagctcg tcttttgatg cttgctgcag agcacatctt
    13681 gaaccctaaa gatggtaaac cagttgttac cccatctcag gatatggttc ttggtaacta
    13741 ctatcttacg atggaagatg ctggtcgcga aggcgaaggt atgattttca aggataaaga
    13801 cgaagctgtg atggcatatc gtaatggcta tgctcatctt catagtcgtg tgggtattgc
    13861 tgttgacagc atgccaaaca aaccttggaa agacagtcaa agacataaaa ttatggtgac
    13921 aactgttggt aagattttgt ttaacgacat catgccagag gaccttcctt acctccaaga
    13981 gccaaacaat gccaacttga cagaaggaac acctgataaa tacttccttg aacctggtca
    14041 agacatccaa gaagtgattg acggcttaga catcaatgtg ccatttaaga agaaaaacct
    14101 cggtaacatc attgcggaaa ccttcaaacg tttccgtaca acagaaacat cagccttcct
    14161 tgaccgcttg aaagaccttg gttactacca ttcaaccctt gctggtttga cagtgggtat
    14221 cgctgacatt cctgttattg ataataaagc tgaaatcatt gatgctgctc accatcgtgt
    14281 tgaagaaatt aacaaagcct tccgtcgtgg tttgatgaca gatgatgacc gttatgttgc
    14341 cgttacaaca acatggcgtg aagctaaaga agcccttgaa aaacgtctga ttgaaacaca
    14401 agatcctaag aacccaatcg ttatgatgat ggactcaggt gcccgtggta acatctctaa
    14461 cttctcacag cttgccggta tgcgtggttt gatggctgct cctaacggac gcatcatgga
    14521 acttcctatc ttgtcaaact tccgtgaagg tttgagcgtt ttggaaatgt tcttctcaac
    14581 ccacggtgca cgtaaaggga tgaccgatac ggcccttaaa acagccgact caggttatct
    14641 tactcgtcgt ttggttgacg ttgcccaaga tgttatcatt cgtgaggacg attgtggcac
    14701 tgatcgtggt cttcttatcc gtgctattac agatggtaaa gaagttaccg aaacgcttga
    14761 agagcgtctt caaggtcgtt acacacgtaa atcagtcaaa caccctgaaa ctggtgaagt
    14821 cttgattggt gctgaccaat taatcactga agacatggct cgtaagattg ttgatgcagg
    14881 tgttgaagaa gtgaccattc gttctgtctt tacctgtgcg actcgtcatg gtgtctgccg
    14941 tcactgttat ggtatcaact tggcaactgg tgatgctgtt gaagtgggtg aagcagttgg
    15001 tactattgct gcccaatcta tcggtgagcc tggtactcag cttaccatgc gtaccttcca
    15061 cacgggtggt gtagcctcaa ataccgatat cacccagggt cttcctcgta ttcaagagat
    15121 ctttgaagca cgtaatccta aaggggaagc ggtcattact gaagtgaaag ggaatgtcgt
    15181 cgagattgaa gaagatgcgt caactcgtac caagaaagtc tacgttcaag gtaaaactgg
    15241 catgggcgaa tatgtcgtac catttacagc acgtatgaaa gttgaagttg gcgacgaagt
    15301 taatcgcgga gctgccctta cagaagggtc aattcaaccg aaacgtctcc ttgaagtgcg
    15361 tgataccttg tcagttgaaa cgtaccttct tgcagaagta caaaaagttt accgtagcca
    15421 aggggtagaa atcggagaca aacacgttga ggtaatggtt cgccaaatgc ttcgtaaagt
    15481 tcgtgtcatg gatccaggtg atacagacct ccttccaggt acacttatgg atatttctga
    15541 tttcacagat gctaacaaag atattgttat ctctggtggt atccctgcga catctcgtcc
    15601 tgttcttatg ggtattacta aggcttccct tgaaaccaat tccttcttat cagctgcatc
    15661 cttccaagaa acaactcgtg ttcttacaga tgctgctatc cgtggtaaga aagaccactt
    15721 acttggtctt aaagaaaatg ttatcattgg taaaatcatc ccagcaggta ctggtatggc
    15781 gcgctaccgt aacattgaac cacaagcgat gaatgagatt gaagtgattg atcatacaga
    15841 agtctcagca gaagcagaat aatctcatga aagagtcctt aggggctctt tcttgtctga
    15901 gtttgttggc agtaaaaagc attgacaatc agtcttagtc ccaatgagca gatgtttttc
    15961 aaaatactta tgatttagct ataataatgc ataagaggaa tgggtaatgt gttatgtatc
    16021 aagtaattaa aatgtatggt gattgggagc cttggtggtt catcgatgga tggcaagacg
    16081 atattataga tgagcaacaa tttagtgact ggcaagaagc gcttgattat tttaatcaag
    16141 aatggcagcg catgaaagct atttttccta gttatcatag ccaaaagaat ttgttagcta
    16201 ctttttggga aaaagaagat aaaagatggt gcgaggactg tgacgaagat ttgcagcagt
    16261 ttcattctct tttactcctt aaaaataaag atattgtacc aagcaataat tatattcctg
    16321 aatttgaaca acgaaatgat tcaccacagg tagcttatct ttgcaagtta aacctttaag
    16381 tgtttgttaa aaacaaaata agttaaaaga aaatatcatt tcttatgata ttttcttttt
    16441 ttgtttacga ataaatgagt aaggaggaat tatggtacaa gcattagcaa aagctattct
    16501 agcaaaagct gaacaggttc aggcacaaga tatttatatt ttgccaagag cagatcaata
    16561 tgatcttttt ttacgaatag gagatgaaag gagattagtt gatgtttatc agagcgatcg
    16621 gatggctcct cttattagtc actttaaatt cgttgcagga atgatagttg gtgaaaagag
    16681 acgttgtcag gtgggttcat gtgattataa gcttagtaaa gataagcagt tatctttgcg
    16741 cttatctagc gtgggtgatt atcgcgggca agaaagctta gtgattcgtc tgcttcatca
    16801 tcaaaataaa agtgtacatt attggtttga tggattgaca aaagtagcca atcaagttgg
    16861 cggtagaggg ttgtatttat ttgcaggacc agttgggtct gggaagacaa ccttgatgta
    16921 ccagctgatt tcgagttatc atcaagaagc acaggttatt agtatagaag atcctgtaga
    16981 aattaaaaat caccaaattt tacaattaca agtgaatgat gatattggta tgacttatga
    17041 caatttgatc aaactgtctt tacgccatcg accagatatt ttagttattg gtgagattcg
    17101 agatagtcaa acagcaagag ccgttattag ggctagtcta acaggtgcca tggttttttc
    17161 aacggttcac gctaaaagta tctcgggtgt ttatgcaaga ttgttagaac ttggtataac
    17221 gaaagcagaa ctgtctaatt gcttagcatt aattgcttac caaaggttac ttaatggagg
    17281 agcattgatt gactctactc aaaacgaatt tgaatattat tcctcatcga actggaatca
    17341 acaaattgat cagcttcttg aggcaggaca tctcaatccc aagcaagcta agcttgaaaa
    17401 aattatctag taaacatcag cataaattca ttcaattact agctaatctt ttatctacag
    17461 gatttagctt cgcagaggtt attgcttttt taaaaagaag ccagttgctt cagctagatt
    17521 atgttcttaa aatggaagag tctttattaa aaggacaagg cttagcagat atgttgtcgg
    17581 gtttaggttt ttcagatgct attcttactc aaattagttt agctgataga cacggtaata
    17641 ttgaaacaac attagtagcg attcaacatt acttgaacca aatggcaagg atcagacgaa
    17701 aaactgttga agttatcacc tatcctctta ttcttttact ttttcttttt gtgatgatgc
    17761 tagggttgag acgctattta gtccctcaat tagaaactca aaatcagata acttactttc
    17821 ttaaccattt tcctgccttc tttataggtt tttgctcagg tcttattttg ttgttcggga
    17881 tggtatggct acgatggcga tctcaaagcc gcttgaaact ctatagtcgg ctaagtcgtt
    17941 atcctttttt aggtaaactg ttaaaacaat acttaactag ttattatgct agagaatgga
    18001 gtacgttaat aggtcaaggt cttgatttga tgactatttt agacattatg gccattgaga
    18061 aatcctcact aatgaaagaa ttagctgagg acatcagaat gagtctgctt gaagggcaag
    18121 cctttcacat taaagtagct acctaccctt tttttaaaaa agaattaagt ttaatgattg
    18181 aatacggtga aatcaaatcg aaactggggg ttgagttgga aatctatgcc caggaaagct
    18241 gggaacaatt ttttagtcag ctttatcaag tgacacaact tattcaacca gctatttttt
    18301 tagtagttgc tgtgacaatc gtcatgattt atgcggcaat cctattacca atttaccaaa
    18361 atatgggagg tattttttaa gatgattaat caatggaaca acttacgaca caagaagtta
    18421 aaaggattta ctcttctaga aatgttattg gtgattcttg tcatcagtgt tttgatgcta
    18481 ttatttgtgc ctaatttaag caagcaaaaa gacagggtta cagaaacagg taatgccgct
    18541 gttgttaaat tagtggagaa tcaagcagaa ctatatgaat tatctcaagg ctcaaaacca
    18601 agtttgagcc agttaaaggc agatggtagt atcactgaga aacaagaaaa agcttatcaa
    18661 gactattatg acaaacataa aaatgaaaaa gcccgtctta gcaattaaag cttttacttt
    18721 gcttgaaact ttactaagtt tgtcagtgat gagtttcatt atattgggat tgtctgtacc
    18781 agtgacaaaa agctatcaaa aagtagaaga gcatctgttt tttagccatt ttgaacattt
    18841 gtatcgacat cagcaaaagt tagccatatt acagcaaaaa cagcgcgtct tggatatttc
    18901 ttcaacaaaa attgttacag aaggtaatag cctaacagtt cctaaatcaa taacagtgaa
    18961 tcatccttat cggttagtta ttgatcagat gggaggcaac cattccttag ctaaaattat
    19021 ttttgacatg actgatcgac gctttaaata ccaattttat ctagggagtg ggaattatca
    19081 aaaaacaagt caaagcttac atagcccttg aaagtatgat tgcaacaggc atcctcttta
    19141 gtattgtcat tctcgtctta agcagtttac agcagagtca ggctgctcta acgtactatc
    19201 gaaagcagca agaaaagctt aatctagcct tgatggcagt acaaactaga actaaagaga
    19261 tgacattgaa tggttgtcat attactattt tacgtacgga tagatacatt agtattcacg
    19321 atgacgaagg agaagtgatg aagattgagt aaacaattaa gtaacataaa agcttttacc
    19381 ctcctagagg cgttaatagc cttactcgtg atatcagggt ctttattggt ttatcaaggt
    19441 ttgacccaaa ccctccttaa acgtagccat tacctagccc gtcatgatca agacaattgg
    19501 ctcttatttt ctcatcaatt gcgagaggag ttaagtggag caagattttg caaagtagct
    19561 gataataaac tatacgttga aaaaggaaag aaagtactag cttttggcca atttaaaagt
    19621 catgattttc gaaaatcagc tagtaatgga aaaggatatc aacccatgtt atttggaata
    19681 tcacgtagtc atattcacat agagcagtca cagatttgca ttactttaaa gtggaaaagt
    19741 gggttagaaa ggacttttta ttatgccttt caagactaat ctcaaagcag gcgtcctttt
    19801 gtatgctatg tttatggcta gtattttttt gctggtttta caggtttacc tttctcaagt
    19861 gacagctcta cacaaggaat accaagctca aactgactat gttaaagccc gactgatagc
    19921 agaaatagtt tatcaagatc atagatataa agcttctaat cctgtctttt ttaaaggtgg
    19981 tcaagtcatt tgtcgagagc gaaaagagag atggatgtta attgttaagt tagatcagca
    20041 acgacagtat cagtttgaat accttaaacc caaacaatat agtcaataaa tagtattgtt
    20101 gtcataaatc cttaaaatga tccaatatat agtaattaaa ggtgacactt cttttcattt
    20161 caagtgtaat ttggtatgat aaggttatga cttttgaaaa aattgaagaa gcttatcagc
    20221 tgctcttaga gaactgtcaa ctaattgaaa atgatctaaa aacacatata tacgatgcca
    20281 ttgttgaaca aaactccttt tatttagggg ctgagggagc tagtcctcaa gttgctcaaa
    20341 atagtgataa actgaaagcc ttgtgcctga caaaagaaga atggcgtaag gcctaccagt
    20401 ttctttttat taaggcagct cagactgagc aactccaagc caaccatcag ttcacaccag
    20461 atgctattgg cttcattctg ctgtatcttt tggaacaatt gagtgataaa gatagcttag
    20521 aggtacttga gattggaagt ggaacaggga acctagccca aacccttctc aacaacacga
    20581 gcaagagcct tgattatgta gggattgaac ttgatgatct cttgattgat ctgtcagcca
    20641 gtattgctga gataatggat tcttcagctc attttattca agaagatgcg gtaaggcctc
    20701 aattactaaa agaaagtgac attgtcatca gtgacttacc agttggttat tatcctaacg
    20761 atgatattgc caaacggtac aaggtggcta gttcagataa gcatacctat gcccatcatt
    20821 tattaatgga acagtcttta aaatacttga aaaaagacgg ttttgcgatt tttctggcac
    20881 cagtcaattt attgacgagc cctcagagtc agttattgaa acagtggtta aaagattatg
    20941 ctcaggtggt ggccttgatt acgctaccag attctatttt tggtcatccc tcaaatgcca
    21001 agtccattat tgtcttacaa aaacaaacag accacccaat ggaaaccttt gtctatccaa
    21061 ttcgggattt gaagcttgca gagaatattc atgattttat ggaaaatttc aaaaaatgga
    21121 aactgagtaa tgtcaattaa ttgatttttt gttataataa aaaagcatca cagaaaacga
    21181 tttcaagaga ggttaaaaat gtcaaagaca attgcaatta atgcaggtag ttctagttta
    21241 aaatggcaac tttatcagat gccagaagaa gaagtgttag cacaaggaat tattgagcgt
    21301 atcggtctca aggattctat ttcaacagtt aagtacgatg gcaaaaaaga agagcaaatt
    21361 cttgatattc acgatcatac agaagctgtt aaaatcttat tgaacgattt gattcacttt
    21421 ggaatcattg cagcttatga tgaaattaca ggagttggac accgtgttgt tgctggtggt
    21481 gaacttttca aagaatccgt tgtggttaat gacaaagttc ttgaacagat tgaagaatta
    21541 tccgttttag ctccacttca taatcctgga gcggcggcag ggattcgtgc cttccgtgat
    21601 attttgccag atattaccag tgtttgtgtg tttgacacgt catttcacac cagcatggca
    21661 aaacatactt acctttaccc aattcctcaa aaatattata cggactacaa ggttcgtaaa
    21721 tatggagctc atgggacaag tcataaatat gtggcgcaag aagctgctaa aatgcttggt
    21781 cgtccattag aagaattaaa actaattact gctcatattg gaaatggtgt ctcaattaca
    21841 gctaattacc acggtaaatc agttgatacc tcgatgggct ttacaccact tgctggtcct
    21901 atgatgggaa cacgttctgg tgacattgac ccagctatca ttccttattt aattgagcaa
    21961 gacccagagt taaaagacgc tgctgacgtt gttaatatgt taaacaaaaa atcaggtctt
    22021 agtggggtgt caggcatttc tagtgatatg cgtgatatcg aggctggttt acaagaagat
    22081 aatccagatg ctgttttagc ttacaatatc tttattgatc gcattaaaaa atgcattggt
    22141 caatattttg ctgttttgaa tggagcagat gctttggtct ttacagctgg tatgggtgaa
    22201 aatgcaccat tgatgcgtca agatgttatt ggtggcttaa catggttcgg aatggacatt
    22261 gatcctgaga aaaatgtttt tggataccgt ggtgatattt caacacctga gtcaaaagtg
    22321 aaggttcttg ttatctcaac agacgaagaa ttgtgcatcg cgcgtgacgt tgagcgtttg
    22381 aaaaatacaa aataaaagag actaagtctc aatagattaa ccaagtaagg caacacttta
    22441 cttggttttt tatgaggttt atctgttagt tatggtgcct aggtattagt tctgattagt
    22501 ctccttgctt tttgtaatct tgtgctaggc gatttggatg tcagccttat ttagaagttt
    22561 ttaattgctt caacgctttt cttgtatgtg tttatagagc ccaatgatct aaaagactat
    22621 ttgataacgg tttatgatga gcgtaatcgt gcgattcgaa aacagacaca agtttactgc
    22681 ttttacctga tgattgttct atttgttgcc ttattctttt tcttcccttg cttaaccatt
    22741 cgagaccttg tttcttataa gctagctttg atttttgctt acctttactt gattatcaga
    22801 agtctggtgg ctaagaaaat ggaggcacta gggaaaataa caactaatag tcaaaaacct
    22861 ccgtttgata cgagtcaggt tctttgttag atgacttgtc taacggttga gtttcctgtc
    22921 tggtcaacgg aggtgtttgt attgttgtct gatttgtatt ggggcactta ttttacaagc
    22981 ttttagcctt atcgatggtt ttgtcaatgg cagagctgac agtagttgtg aggccaaggc
    23041 gttctaactc catcagacca gcaatagttg tgccaccagg gctacaaata gcgtcaatga
    23101 aatcgtgcgg actttgagaa ctggtcttga gattgctggc actagccaag actgtttgag
    23161 taacaatctc cagcgccttt gctttaggca tgccattctt gacgccagcc ttagccaaag
    23221 cctcaataaa gagataaata taggcaggac ttgaccctgc taaagcggta aaggtgtcaa
    23281 aatccttttc actaatatca aatgtgctac caaagctatc tgttaagtct cgaacacgtg
    23341 cttgtaattc ctgagacacc aaagcatttc ccgttaaagc ggtactgctt tggagaattt
    23401 gtgcattcat gtttggcatg atacgtagca gcggaaggtc ttgtcctacg aatgttgcta
    23461 gtcgttgaag ggaaatgcct gctgccatag atataatagg ctgtttgaag tgaagcggtt
    23521 tgagtaccgt ttcaaatagt tgaggcttga tgcctaaaat aacaagatca acctggtcaa
    23581 taaggtcttg gtgggacata gcataaggca gtgttaactg ctccgcaatt tccttggacc
    23641 gttctaaaga tgatcctgaa atgataagtt catggggtgt ttgtttaagg cctttgatga
    23701 tagcgctagc cattttgcca acaccaataa tgccaatttt cattctgttg ctccttgtgg
    23761 gatattatgg ttaatcaggc taatgctagt ttagtaacgt ttaatcaagt caacggttga
    23821 gcgatccagt tttttgataa tggcttgtaa gaaggcttgg gcttctacga aatcatccat
    23881 agcgtagagg gtttgatgag agtgaatgta gcgtgcacag actccgatgg ttgttgatgg
    23941 gacaccacca ttttgaaggt gtgcagcacc tgcatctgtg cctcccttgc cacaatagta
    24001 ttggaaattg acaccagcgt cctcagcagt agtcagtaag aagtcgcgca tatctttgag
    24061 catgacatgg cctgggtcgt agaaacgcaa caaggtgcca tccccgattg ttccaggatt
    24121 gccataaata tcaccagcag gcgaacaatc tactgcgaaa aagagttcag ggtcgaactt
    24181 ggtggttgag acgtgggctc cgcgcagacc aacttcttct tgaacgttag cacctgcaat
    24241 tagggtgttg ttaaggtctt gtccttttaa cgcttcaagc atttctgtta tcatgagaac
    24301 gccatagcga ttgtcccaag cttttgaaat aatatttttt tgattggctg ttaggatcgt
    24361 ttcagattga gggacaataa tatcacccgg tgtaatgcca aagctttcag cttctgcctt
    24421 atctgtaaag ccaccatcaa acacaatatc ttcgatatgt ggtagactag cagagccatt
    24481 tgccccacgg agaaaatgag gaggtaccga tcctgaaata aggggaataa cttggccagt
    24541 gcgtgtgtaa agggtaaacc gttgtgaact gacaacaagt gggttccaac caccgatacc
    24601 aaccgcgcgt agcgttccgt caactttgat atcactgacc ataaaaccga cttcgtccat
    24661 gtgcgcagct actaaaatac ggggggcttt ttcagcttta ctatctctga taccaaaaat
    24721 gccaccaagc ccgtctgttt caacacggtc aaccagcggg gttattttgg tgcgtaggta
    24781 gtcacgaacg ctatgttcat agcccgcaat gccatccagt tcggtaactt ctttgatttt
    24841 tgagaataag tctgtcattt ttcatctcca tttaaaaggt ttcagaccag ttcaacgcgg
    24901 tcatctcctt atattctacc actttttaag taagaatggg tttcacagaa aagaaaaatc
    24961 ccagagacta gagatctctg gaagaagtgt ttgtcttttg gcgataatct gtttttttag
    25021 gcagcaagga aatcattaaa atgataaagc acaagctggt taataagaat agtagggcgc
    25081 ttaggatgcg aaaagactct tcactagcga aaagtaagga taatggagtc ataaggagaa
    25141 ccttccattt taggttaatc agtgattttt atagcgtggt taaattaata ataaaccaca
    25201 cctaatcaac gtacctttag tttagttgtt tttactattt ttgtcaatac ataacagtag
    25261 aaatctttag ttttcttatt tcagatcgtc caatttgatc tttttatgat aaaatgaggg
    25321 atatgagtaa aaagaaaata ggtatgattt caggtatctt tggatttagt ttagctattg
    25381 gcctaggaat agttatcaaa gattattgcc aagataggaa gcgccgacaa atgacaaggg
    25441 atttacgcac ctttttttca cctttaggac aaatcgaagt tttatatatc aatccttgtc
    25501 aggtcaaaca agattatatt tcaggtgggg ttgttatgtc aaacggcaaa cagtaccaat
    25561 tcacctatca cagtcgacaa attagttttg aggaggacaa gtgatgatca gaccgacttc
    25621 ttatgagtca ttagcggctc ttgttgaaaa agaagataag ctggtgttat tttttacggc
    25681 agactggtgt ccagactgtc aatttattta tcctattatg ccagaaattg aagcagaact
    25741 tacagatatg acttttgttt gtgttaatcg tgatcagttt atagaggtag cacaaaagtg
    25801 ggatattttt ggtattccta gttttgtcgt gattgaaaaa ggtcaggaag tagggcgtct
    25861 ggttaacaaa atgagaaaga caaaaactga gattatgcat tttttagctg cttatcaata
    25921 agaaaagagg aagaataaat gatttttgca tacaataaag aacaagttgg cgatgtcttg
    25981 atggttatct tacaagacac caaagatatc aaacgtcaag tagaacgaaa aggcaaagta
    26041 gcccgtgttt ttgcagaaga aagcggcaaa acccttgctt ggaatatctt tgaagcgtca
    26101 agcttgatta ctattgaagg caatggacag atttttttga cagacgagga ccttgcaaga
    26161 ttaaatgcag agcttgctaa ggaaggattt tcagaaaggc ttgaaccgac tgtgggacct
    26221 gtttttgtgg tcggtcaaat tgttgagatg gtggctcatc tagatagcga ccatcttaat
    26281 atctgtcaag tggctattgg tgaagatcaa acggttcaaa tcgtagcggg cgcaccaaat
    26341 gctgcgcttg gtttaaaaac gattgttgcc ttaccaggtg ctataatgcc aaatggtagt
    26401 ctgattttcc caggaaaatt gcgtggtgaa gaaagttatg gtatgatgtg ctctcctcgt
    26461 gagttagcct tgccaaatgc accgcaaaaa cgtggcatta ttgaacttga tgagtcagct
    26521 gtggtaggag aagcttttga cccagccaaa cattggaaag gttagaaaaa ccagctgaaa
    26581 taagactgta tttaactaaa tgaccagaaa aaaaggatta ggatccccta ttcctttttt
    26641 cttatgtttt caaaaacgtt taaaatgaaa cttattttac cacaattttt acgaataata
    26701 agataaggag gtcagtatgt ataataaagt gatagcaatc ggtcgtttgg tagctaaacc
    26761 agaattggta aaaacagcta cggataagca tgtagcacgt ctctctttag ctgttaatcg
    26821 aagatttaaa aatgcttctg gagagcgaga agctgatttt atttcagttg ttgtttgggg
    26881 aaagttagca gaaactctgg tttcttatgc tagcaaaggt agtttgatat ctattgatgg
    26941 cgaacttagg acccgcaagt atgataaaga tgggcaagtg cattatgtga cagaagttct
    27001 ctgccaatca tttcaactgc ttgaaagtcg tgctcagcgc gctatgagag aaaataatgt
    27061 tactaatgat ctagttgatt tagtcttaga agaagatact cttccctttt gatagaggat
    27121 aatgcttctc atcagggttc agctgattac tgaaatatat gatgaggtga tatccgagca
    27181 acaaaagtgt gactagatac ttctgataaa aataaaaaaa caccttacga gtatgaacaa
    27241 agtttcaagt gctagatgtt ggaactttgt tcatcatagg aatagtaggg tgttttttag
    27301 tgtattactt ctttttgttg ctggtgttaa ggtttacttg cttacaagtg gttatcaggc
    27361 cactagaact cttataataa atggagctct ttgagtttgg tgtcaatcat ttttaagaca
    27421 gtcgccaaat cttgtgggtt ttgaacgaaa tcaagggaat tgccatcaat tttcattttt
    27481 ggagagacct tgtagtcttc gtaccaggtt gggtattcac cgtggacttg atggtaatat
    27541 tgctcaagac taggattgcc gtcgacctgc tcaaaacttc ggccacgttt ttcaatgcgc
    27601 tcaagcattt tgtcaaaaga cacatcaatg tagatgagaa gatcagggcg ttttttaggc
    27661 atgccttcta gttcttctaa catgttggcg agaagttcct gatagatgtc aagttctgtc
    27721 ttagtgacat tgccattttt gtagttaagt tttaagaaga gttcgtcttc aaaaatagag
    27781 cggtcaagaa tgttgttatc ggcttgataa gcttctttga tggacttaaa ccgtttattc
    27841 aaaaaataaa tttgaagtaa aaaggcgtac tttttagggt cttggtagta gaggtctagc
    27901 acggggttat tatcaacagc ttcgtaaaaa acgtcagttc ctaaatgctc tccaagtgca
    27961 gcagcaagcg agctcttgcc agccccaatt gttccagcta gtacaatcaa catgcgtctc
    28021 cttctaatgt cattagcgta ctgtttcgaa gatggcttca acctcagcta gagtctcagc
    28081 gcgtgaaaca gcaccacgaa ctttggcagc acctgctgtt ccacgaagat agtgtggcgc
    28141 taagccccga aattcccgaa cagcaatggt ttcacctttg aggttaatca ggcgtttaag
    28201 gtggtctttg gcgatgtcta attttttggc aaagggaaga tctggcaatt cttgaccagt
    28261 ttcaaagaaa tgattgattt gggtaaaaag ataaggattg ttcatggctg cgcggccaat
    28321 catcacggca tctacaccga tttcttcaat cataaatttg gcgtcttgca ccgaacgcac
    28381 gtccccattt ccaataaagg gaatcttagt gatagcctta gaaactcggg ctaatgtctc
    28441 atggtcgcag gttcctgtat acatttgttc acgggtacga ccgtgcatgg caagagcaga
    28501 tacacctgcc gactcagcgg caagggcatt ctcaacggca agtgaactat ccgcccaacc
    28561 tgtacgcatt ttgacagtca gtggaatatc taaaacagac gtgacttcct tgacaatgtg
    28621 gtaaatctta tcagggtcac ggagccactt ggcaccagcc tcgtttttga caactttatt
    28681 aacagggcag cccatattaa tatcaacaat atcggccttg gtattggttt gaatgaaatc
    28741 agctgcacgt ttcaaccctt ctgcatcacc accaaataat tgaatggaca tagggtgctc
    28801 attctcgtca atatggagca tatggagggt cttttcgttg ttgtagagca gccctttttc
    28861 ggaaatcatt tccataacca ccaaaccagc accaaattct ttggcgatgg tacgaaaggc
    28921 agagttggtc acaccagcca tgggagcaag gacagtgcgg tgagggattt ccacatcacc
    28981 aatcctaaag gaagaattaa gctttatcat tgataatggc ctccaaatca ctttcattaa
    29041 attggtactt ggtaccacaa aattggcaaa caatctcagc acccttatct tcgtcaatca
    29101 tggcctgtaa atctgctttt ggcaaagtca ttagggctgc ttcaaaacgt tctctagaac
    29161 agtcacactg aaaactcaga ggttcttcag aaagacgctt gtaaggttca tctccataga
    29221 tggcctccaa aagggcatcc acatgatttt tggaagctag taggtgagaa atggcaggca
    29281 tttcttgcag gcgtttttca tagcgagcaa cctcttcttc agaagctcct ggtagcacct
    29341 gcaccataaa gccaccagca accttgacct tatcattttc atctaaaagc acattaagtc
    29401 cgattgcaga tggtgtttgc tctgattcgg ttaagtagta ggcaaaatcc tcaccaattt
    29461 ccccagtaat aagaggcgtt gttgaggtgt aagggttacc tgtgccataa tcaataatcg
    29521 tcacaaaatg accattcccc ataaaaggcc caacaaggac ttcacctgtt gcggtctttt
    29581 taatatcgac accagtattt tgaatgtaac ctttcacatg tcctttggta tctgccacag
    29641 agataatgtg tccaaaagaa gaatcaccaa tcactttgac ggtgattcta ctatcgcctt
    29701 tttgattagc cgccaaaatc tggttggcga tcaaggtacg gccaagcgca acagtagacg
    29761 atgacagcgt gttgtgtttt tcttgagcta atgcaactgt ctcagtgcta tcaaggacat
    29821 aagccctaaa agaccctgat tgtgctatcg atttaattat tttatccata acttagatta
    29881 tagcataaag tgtaaaactt gtattgacag gattgcttga aaaatcaata cagatagaca
    29941 gtaaaaaatc ccagagaatg actcgggatt aagttaaggt gtggtctaaa gtcgcgcaat
    30001 gtggtgacat ggcgcttatg ttaattgctt ggttaaatca gcttggaatt tttcctcttt
    30061 aacttgatac atcaattctt ggatagacag aatcgattca tcaaaagata tttcagcaac
    30121 agcaattcct tttgtaagtt catggtgaac aaaaggaatc agttgactgt gagtgatgac
    30181 caaatctggc tttaaatcag gaatttgata aacattatct tgcaatagat aataggaatg
    30241 aaaatcaatg cttttatccg agaaatacct tgggaaagaa tctgttagga gatgagcatt
    30301 gataaaatta ctggctacga aaacaacaac taaaggaggt tggatatttc ttagaatttg
    30361 ctcgacatag tggcaaaaaa gatgaaaatg cttatggttc aagtaacgct taccaggaag
    30421 tttggccatc cactcttcga caattaactt taaggacgta tagagttttt ggtttccttt
    30481 atagtacgga gaaacgaata agttggtctc aggaataaaa tgttgcagat taaacaagaa
    30541 tgattttgaa aaaaacataa gagcttttac taaactagcc ttttgctctt ttaggttagg
    30601 taaaagagtg atgataggat ttaaaagcag gcgaaaagta tcattttctt caaaaagttg
    30661 acaacattgt ctgatatgct caggtgtcca ttgtaagctc gcaaaagaat tattagcggt
    30721 gatataaatt aaatagaggt agtccaaatc tcctgctgaa aagtttagtt ggcagtaagt
    30781 ttcgataata tcacggctac tttttttcaa agaatcgtag acaaaaagtt tttttaattg
    30841 ttgaaaaatt ctggtttggg gaatagttac cgaaaattga tgccgcttcc acgataaagc
    30901 taataaaatg tcatagaaag aaaacgattc cgataaccaa ggagaagttt taaggtgggt
    30961 ggaactatgg gataaaaagc tatgaataat gtttttgtct tgctgcgtca agtcataaac
    31021 tttaatgcca aacttactat atagcagagc gatgaggtaa cggatacgat attcctcacc
    31081 gacaatcttg ttcttagaga gttttaattc aaagtttctt aataaaggaa tcaatgcttc
    31141 gcgcatccga taagctgagg agtttgataa aaaatgactt cttgcaaaat ccgtaagggg
    31201 acgagagtgg gaaccatttt ttattaaaaa cgctagtaat tgtaagacat tagatgatgc
    31261 atagagttgg taaagataag tttctttaga aggatgtgta aattggcaag atatcatcct
    31321 tttttggatg gtcatagaca gactatcagg gaaaaaggca ttcagctcct cacaataatg
    31381 gtttagttgt aaaaaggtta agccagtttt ttctgctacc tcagttattg gcaaagaaga
    31441 tgtcttaaaa aacaagacaa ctaactgaca ttttgattcg attgatgatt ccaagtattt
    31501 ttctatcaag gaaaggggtc ctctcttcct acacttagaa agccaaataa gtctttgata
    31561 agtgtattct cctatttcaa ttctatctaa gctaaaaata gaaatcaaat ctaatggttt
    31621 ttggtgaaaa gtcgaaacct tttgaaatag ctttaaagca atattttctc aaaaaatcat
    31681 tttcaaaaac attaatttgg tgaaatatac aatcaaaaaa atatctttct tgacaataac
    31741 atggtaagct catatatatt tgcgagagga gagaaaatga ataacaaaat gtttttgaac
    31801 aaagaagccg gttttttggt acacacaaaa agaaaaaggc gatttgctgt cactttagtg
    31861 ggagtctttt ttctgctttt ggcatgtgcg ggtgctatcg gttttggtca agtagcctat
    31921 gctgcggatg agaagactgt gccgaatttt aaaagcccag atccagatta tccctggtat
    31981 ggttatgatt cgtatagagg aatatttgca agatatcaca atttaaaagt aaatctaaaa
    32041 ggaagtaagg agtatcaagc gtattgtttt aacctaacaa aatactttcc tcgccccact
    32101 tatagtacta caaataattt ttacaagaaa attgatggga gtggatcagc gttcaaatct
    32161 tatgcagcga atcctagggt tttagatgag aatttagata aattagaaaa aaatatactg
    32221 aatgtaattt ataatggata taaaagtaat gcaaatggtt ttatgaatgg tatagaagat
    32281 cttaatgcta tactagtaac tcaaaacgct atttggtact attcagatag tgctccatta
    32341 aatgatgtta ataaaatgtg ggaaagagag gttcggaatg gggagattag tgagtcacaa
    32401 gttactttaa tgcgtgaggc attgaaaaaa ctaattgatc ccaatttaga agctactgca
    32461 gctaataaaa tcccatcagg atatcgttta aatatcttta agtctgaaaa tgaagattac
    32521 caaaatcttt taagtgctga atatgtacct gatgatcccc ctaaacctgg tgatacgtca
    32581 gaacataatc ctaaaactcc cgagttggat ggcactccaa ttcccgagga cccaaaacgt
    32641 ccagatgaga gttcagaacc tgcgcttccc ccatt
//
LOCUS       DAUGUF010000023        27969 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUGUF010000023 DAUGUF010000000
VERSION     DAUGUF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27969
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.023"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            22..1194
                     /gene="sda1"
                     /locus_tag="VIB71_001074"
     CDS             22..1194
                     /gene="sda1"
                     /locus_tag="VIB71_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase Sda1"
                     /protein_id="HEQ8822809.1"
                     /translation="MSKHWRHLIIHSALTILATLFLGILPITENTSSTIYAESGTISN
                     NWSIEQHPNYYHVEGKAQLDIKNFPELYRTTERVYKKSGQSTKPVTVSNIHYSVLDGY
                     GRSGEAYGIITKDMIDMSAGYREKWESKPEPSGWYSYFFKNTNQRATESDYKHSPKNV
                     SKISNNIKASILLSNGNVRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNNDRK
                     GGMQYIENKVLDHIKRNPKVHVYYKATPVYQGSELLPRAVLVSALSSDGFIDETVRVF
                     NNVAGFNIDYQNGGLLSSTADVDINNVEENEIETTDDEIEEGIENEPDTDALKKDNKD
                     TSLQDTVYVASNGQSDVYWYNKDSMPKTVNLEKVVEMSEQVALTRGKHHSTQENIE"
     gene            complement(1310..2506)
                     /locus_tag="VIB71_001075"
     CDS             complement(1310..2506)
                     /locus_tag="VIB71_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8822810.1"
                     /translation="MTFLDNIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFNTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYQ
                     SVVGETDYKKACHAIKDAGYATASGYAELLIQLIEENDLQKWDKEILTNQKEVTMTTA
                     NEIVKYCVDLANSGMGVDKDGAYGTQCCDLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHAHQTVDTAPQNSDTIVETPKSGTFTLDVVEINIR
                     RWPSLASEVVGSYKQGDTVSFDSEGYANGYYWISYLGGSGMRNYMAIGITDKDGNIIS
                     LWGKLN"
     gene            complement(2617..2802)
                     /locus_tag="VIB71_001076"
     CDS             complement(2617..2802)
                     /locus_tag="VIB71_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822811.1"
                     /translation="MSKWFKKVGIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKDEE"
     gene            complement(2799..3098)
                     /locus_tag="VIB71_001077"
     CDS             complement(2799..3098)
                     /locus_tag="VIB71_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822812.1"
                     /translation="MHFDLLQAGAAAAALMSVFGLWKAVVTPFKKAMEANEFAMAQLK
                     DSLKELAYELKNLDRDREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            complement(3109..3729)
                     /locus_tag="VIB71_001078"
     CDS             complement(3109..3729)
                     /locus_tag="VIB71_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822813.1"
                     /translation="MRNWKVTGNYPQWDGTGAVVDTQVIITDDRGAVISEKVKKDLRT
                     ANDAEIIEAALEEFKKTAYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHVLTSGGKIDPDIYKGMLELIEPAKKGEYKEHDIFTVVDADKDTD
                     GVAGEGNLVFVYVNDKFTYDAQTLKDLEELEDKVTVIKYADLVKQD"
     gene            complement(3732..3893)
                     /locus_tag="VIB71_001079"
     CDS             complement(3732..3893)
                     /locus_tag="VIB71_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822814.1"
                     /translation="MQEKLLGKIINDLTLKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            complement(3902..5809)
                     /locus_tag="VIB71_001080"
     CDS             complement(3902..5809)
                     /locus_tag="VIB71_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8822815.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFKADGDTKSVKLANNKCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGSGESTGLFKNLEGALSQLKELNLELTDTVNSQ
                     LWAKIKLTTNGMLREYHRDNITTEIVESANGIATRISEDTDKKLALINETVSGIRRDY
                     QDADRQLSSTYQAGINGLKATMANDKNDLKAVIQATAQGLSQKYDDEIQQLSAKITTT
                     SSGTTEAYESKLADLRAEFTRSHQGMRTVLESRISGLQSTQQSTAYQISQEIKNREGA
                     VSRVQQDLASYQRRLQDTEKNYSSLTQTVRGLQSTVSAPNRGLESRVTQLAGLIEQKV
                     TRGEMESYIRGAGDSIMLAIKGKLPQSKMSASEIVSAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIEHTIT
                     SLLEGKVIRARNGAMMIDLNNSTIDFNSDASINFNSNNNALVRKSGTHTAFVHFGNAT
                     PKNFTRSALYASIGITSSGDGINSASSGRFCGARFFRTASGYEHTASVDQAEIYGDTI
                     IFADDFGINRGFKMTPTGVNTLVDINKMYYAIVALARCWKHLQNVGWDTTHPNFTSAI
                     MNEHSNYMTGI"
     gene            complement(5820..6455)
                     /locus_tag="VIB71_001081"
     CDS             complement(5820..6455)
                     /locus_tag="VIB71_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822816.1"
                     /translation="MAVQEIPDTYFYRLDSQSIDGTLLQKASLVVDQFYIKIDDYYSF
                     YTDQDVDVYKIISSTQADVYKANKYNYQSLSKPDTSVQKPSAAMGLYQSITIDGLPIA
                     RVICNNQVIWSQSAEPQEVYNITAYVDANVSKLNDYAVIDYNQDFATYGVVWHRVDKV
                     AVEVDGKIVAKLQKPVRTVAGGGAMLSIETWTYPFDGIDKYKNPTFKISQH"
     gene            complement(6455..7510)
                     /locus_tag="VIB71_001082"
     CDS             complement(6455..7510)
                     /locus_tag="VIB71_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ8822817.1"
                     /translation="MTLEERIPIKVLFDRKDAAEWQKLNPVVDDGELVVELDTHRLKV
                     GDGKLNYNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTSIA
                     DITKVGETLTITLSDDTQKTFSIPNGQKGDRGKGVESARVDEEGNLFVKFEEESEKLV
                     GNIKGQKGDKGDSLKFEDLTSDQIAQIKAKDVDLSAYATKAELKEIDVSKQLADYLSK
                     AEANSTYAKASHKHSLSDITDLNLDRYATKIELQNKASTYHRHRTSDIDGIDEYLKQT
                     DLPQDIVKQSDIRDVVRNAQLSGYVRLADIQYQLNNIGKLKDVATGQYLSVRVVDKGK
                     VPYNTSGLIVFERSGGK"
     gene            complement(7507..9489)
                     /locus_tag="VIB71_001083"
     CDS             complement(7507..9489)
                     /locus_tag="VIB71_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8822818.1"
                     /translation="MITFLDHRDIEYGAISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLMRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINRRTDKELEEFRETL
                     KNLALPEEAIKKITDAIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEIIGTDGKTRY
                     NKNLLVGNPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLNKVAITLIQANN
                     KGLKLVLTPTKAKMEPQTFEVTKDKQSIEVYPLSYKGVLTGDWYKSKQIDLTASEGQI
                     LALDMAYKAVVDAKGATITAKQSSNPKIILDGRRDR"
     gene            complement(9499..10341)
                     /locus_tag="VIB71_001084"
     CDS             complement(9499..10341)
                     /locus_tag="VIB71_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8822819.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            complement(10353..14735)
                     /locus_tag="VIB71_001085"
     CDS             complement(10353..14735)
                     /locus_tag="VIB71_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEQ8822820.1"
                     /translation="MPGTFDGSIFADIGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVDIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGRQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVVQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSALSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINTVLGDFAHTGELSGQAFDNLKAKITSLAPKVIALWA
                     VMNPASAIATIMPLLSLFGKVGLALGSLGASVGVFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IDQLLNTAVTKGPSIIQGLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQ
                     LITSLVQGIGQNATSLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIGSFGNSLQANLPSIISHGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIVQSAVQIIQSLVSGLTQALPQIIAAG
                     IQLVVQLAVALIKGLPQIISAGIQLITGLGKAMLEAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATAMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFA"
     gene            complement(14750..14983)
                     /locus_tag="VIB71_001086"
     CDS             complement(14750..14983)
                     /locus_tag="VIB71_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822821.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            complement(15058..15513)
                     /locus_tag="VIB71_001087"
     CDS             complement(15058..15513)
                     /locus_tag="VIB71_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822822.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            complement(15567..16166)
                     /locus_tag="VIB71_001088"
     CDS             complement(15567..16166)
                     /locus_tag="VIB71_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8822823.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQISESAGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            complement(16178..16537)
                     /locus_tag="VIB71_001089"
     CDS             complement(16178..16537)
                     /locus_tag="VIB71_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822824.1"
                     /translation="MDYSPETLYLKKVKNRLGALGIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARLLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            complement(16541..16885)
                     /locus_tag="VIB71_001090"
     CDS             complement(16541..16885)
                     /locus_tag="VIB71_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ8822825.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQRLLHYRVVSPALYSIYLELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            complement(16882..17160)
                     /locus_tag="VIB71_001091"
     CDS             complement(16882..17160)
                     /locus_tag="VIB71_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822826.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            complement(17171..17527)
                     /locus_tag="VIB71_001092"
     CDS             complement(17171..17527)
                     /locus_tag="VIB71_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ8822827.1"
                     /translation="MGDKQLIDDIKLFIGISKDDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            complement(17539..18426)
                     /locus_tag="VIB71_001093"
     CDS             complement(17539..18426)
                     /locus_tag="VIB71_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ8822828.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAESIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            complement(18439..19008)
                     /locus_tag="VIB71_001094"
     CDS             complement(18439..19008)
                     /locus_tag="VIB71_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8822829.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLTTTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            complement(19164..19430)
                     /locus_tag="VIB71_001095"
     CDS             complement(19164..19430)
                     /locus_tag="VIB71_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822830.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            complement(19433..19621)
                     /locus_tag="VIB71_001096"
     CDS             complement(19433..19621)
                     /locus_tag="VIB71_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822831.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            complement(19652..21097)
                     /locus_tag="VIB71_001097"
     CDS             complement(19652..21097)
                     /locus_tag="VIB71_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ8822832.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRRDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFNCRTTLIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNG
                     HKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDRVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            complement(21057..22589)
                     /locus_tag="VIB71_001098"
     CDS             complement(21057..22589)
                     /locus_tag="VIB71_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8822833.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYNIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            complement(22605..23882)
                     /locus_tag="VIB71_001099"
     CDS             complement(22605..23882)
                     /locus_tag="VIB71_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8822834.1"
                     /translation="MTIKQRPKINIVIKYPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            complement(23872..24324)
                     /locus_tag="VIB71_001100"
     CDS             complement(23872..24324)
                     /locus_tag="VIB71_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEQ8822835.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            complement(24414..24830)
                     /locus_tag="VIB71_001101"
     CDS             complement(24414..24830)
                     /locus_tag="VIB71_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEQ8822836.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            complement(24827..25018)
                     /locus_tag="VIB71_001102"
     CDS             complement(24827..25018)
                     /locus_tag="VIB71_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822837.1"
                     /translation="MKIEFFLKQGPTKSVSNYGEICIDEVIGAMKNNDVIALNGKNNA
                     VIIPKQNISHVIIHKEVTG"
     gene            complement(25008..25859)
                     /locus_tag="VIB71_001103"
     CDS             complement(25008..25859)
                     /locus_tag="VIB71_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEQ8822838.1"
                     /translation="MEIKCGNCLELLAELTDGLIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASQKLTKNGGMIIFNDWKNLGDIARHCEKNGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGVWVVRKKSKWVFNRKSEKYDRPEYRYPVVAGAEKTQH
                     PTQKPVALMKDIITRHTTKGAVVLDPFMGSGSTGVACLLTGRDFIGYELNKDYFNIAN
                     KRIAELTGNGGVGMNIIHRMENGIDAVGDLTTYAVPCCPECKNETYSQKHCPFCGENL
                     MEVANEN"
     gene            complement(25868..26134)
                     /locus_tag="VIB71_001104"
     CDS             complement(25868..26134)
                     /locus_tag="VIB71_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822839.1"
                     /translation="MTEELIKPLLEEIKRKDDRLYMQSNVIAVLMTAVIMLLMISIAL
                     QNHYEPQITGLRTQLSRTQKQLKRASEDRARQTKRIAELTGNGG"
     gene            complement(26131..26298)
                     /locus_tag="VIB71_001105"
     CDS             complement(26131..26298)
                     /locus_tag="VIB71_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822840.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLKFWNSCEAT
                     VKEKYTREWKK"
     gene            complement(26299..27621)
                     /locus_tag="VIB71_001106"
     CDS             complement(26299..27621)
                     /locus_tag="VIB71_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ8822841.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKSTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDFERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            complement(27618..27893)
                     /locus_tag="VIB71_001107"
     CDS             complement(27618..27893)
                     /locus_tag="VIB71_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEQ8822842.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMGNWV"
BASE COUNT         7583 a         6242 c         4900 g         9244 t
ORIGIN      
        1 taacaaaagg aggacataaa tatgtctaaa cattggagac atctaattat tcactctgct
       61 ctgaccattc tagctacgtt atttttaggt atactaccaa ttactgaaaa tactagtagt
      121 accatttacg ctgaatcggg cactatttca aataattgga gtatcgagca acaccccaat
      181 tattaccatg ttgaaggtaa agcgcaactg gatattaaaa attttcccga actttatcgt
      241 acaaccgaaa gggtctataa gaaaagtggg caaagtacta aacctgttac agtttccaat
      301 atccattact ctgtacttga tggctacggc cgttctggag aagcttatgg tattatcaca
      361 aaagatatga ttgacatgtc tgctggctat cgtgaaaaat gggaaagcaa accagagcca
      421 agtgggtggt attcttattt cttcaaaaat actaaccaga gagccactga atccgactac
      481 aagcatagcc ccaaaaatgt gagtaagatt tcgaacaata tcaaagctag tattctctta
      541 agtaacggaa atgttcgtaa cggctacctg tttgatagaa gtcatttaat agccgatagc
      601 ttaggaggaa gaccttttag aaataatttg attacgggta cccgcaccca aaacgtaggt
      661 aataatgatc gtaaaggtgg gatgcagtat attgaaaata aagttttaga tcacattaaa
      721 agaaatccta aagtccatgt ttactataaa gcaactcctg tatatcaagg atccgaattg
      781 ctacctagag cagttttagt gtctgcttta tcatctgatg gatttattga cgagacagtt
      841 cgtgtgttta ataatgtagc aggttttaat attgattacc aaaacggtgg actcttatct
      901 tctactgctg acgtagatat taataacgtt gaagaaaatg aaatcgaaac tactgatgac
      961 gagattgaag agggaatcga aaacgagcct gacacggatg cactaaaaaa agataacaaa
     1021 gatacttctt tacaagacac tgtatatgtg gcaagtaatg ggcaatctga tgtatactgg
     1081 tacaacaaag acagtatgcc taaaactgta aacttagaga aagttgtaga aatgagtgaa
     1141 caagtagctt tgactagagg taaacatcat tcaactcaag aaaatataga ataacaaatt
     1201 caacagacca actagaactt gaaatagttt ttatattctt attagttatg cataagcata
     1261 cgaaacacac aaaaaaccgc cctcaatcaa gagagcggtt ttgtcttatc taatttaatt
     1321 taccccaaag gctgataatg ttaccatctt tgtcagttat cccaatagcc atgtaatttc
     1381 gcatacctga gccgccaaga taactaatcc agtagtagcc attggcataa ccctcgctgt
     1441 caaagctgac agtgtctcct tgtttgtagc tacctactac ttcactggct aggcttggcc
     1501 aacgtctaat attaatctcc acaacatcaa gcgtaaaggt accagatttt ggtgtctcta
     1561 cgattgtgtc agagttttgt ggtgctgtat ctaccgtctg atgagcatgg tcaacaggta
     1621 acctaatcca gccgacaacg ccagtaaaat cacgagtatt aaaacgggct ggtccaccta
     1681 cttgtaagct atcccaatta ccgtcaatat tttgctcaac ggttttaata gtatagccat
     1741 cactatcctc gatgacagct cctgtatgtc cgtagggact accagctacc tccatgacaa
     1801 aaaggtcact agctttggga ttgactccag gggcattata tatgacctct agcccttgcg
     1861 cagatgcgct atttaacagg tctatggcat taccccataa atcaatgccg aaccagtttt
     1921 tgacgataaa acatggtaag tcacagcatt gcgtcccata agcaccgtct ttgtcaactc
     1981 ccatacctga attggcaagg tcgacacagt attttacaat ctcatttgcg gttgtcatcg
     2041 ttacctcctt ttgatttgtt aagatttcct tatcccattt ttgtaggtca ttctcctcga
     2101 ttagttggat aagcagctcc gcatatccac ttgccgtggc ataacctgcg tccttgatag
     2161 cgtgacaggc ttttttatag tcagtctcac caacaacaga ctgatagcgt ggattatcgt
     2221 ttaaaaactt gccatggtcg ataatgctat cagtccagct atcataggcc ctaaatcggt
     2281 ccacaatatc cgtgacgata ccaggctggt actcctcctg cgtcttagtg ttaaaagact
     2341 tacctgtcca gcttgcatca gctttaatcc caaacagagc gttatgtggg gcatgtttac
     2401 cccacccgct ctctaagatt gcttgtgctg cggtcaagga tggcaagatt ttgtacttag
     2461 tccagccatc taagcagcct tgcttaatgt tatctaaaaa ggtcatctgt cctccttatc
     2521 tacaaacggg taaaagataa gagcaaccac agataatggc acatacagta ttgcgattgc
     2581 tagtattaac gctaatcgtg tgattgctcg catggcttat tcctcgtctt taatttgtga
     2641 cacgttcatc aggacacatg ttagtcctga tagcagtacc gctgacaaca ttgttggcca
     2701 gttaatatcc gtaatcaaca cgcttgaccc gataagacca accgcagttt gtgccattgt
     2761 tttgattgtt ttaattccta cttttttaaa ccatttgctc atttttcttc ccctttttta
     2821 aatagcgtga taatacgctc tttgttgata ataacttcgt cttcgacgcg acctaaacgc
     2881 tcttcgtgac gatcgataat ttttttggta atttcacgat cgcgatcaag atttttaagc
     2941 tcataagcta actctttgag agagtccttg agttgagcca tggcaaactc attagcttcc
     3001 atggcttttt taaaaggcgt tacaactgcc ttccaaagac caaaaacaga catgagagcc
     3061 gctgccgcag ctcctgcctg tagtaaatca aagtgcatct aaccacctct aatcctgctt
     3121 aaccaaatca gcgtacttga taactgtgac tttatcctct aattcctcta aatctttgag
     3181 tgtttgtgca tcataagtaa acttatcatt gacataaaca aagactaagt tcccctcacc
     3241 ggctacaccg tccgtatctt tatcagcgtc tacaactgta aaaatatcat gctctttgta
     3301 ctcacctttt ttagcaggtt cgatgagctc taacatgcct ttataaatgt caggatcaat
     3361 cttgccaccg cttgtcaaaa cgtggatggt ttgcaagtta atcatctttt gcgtgcgttc
     3421 agcggacact ttagctagtc cagcggctgt ttgagcagtc ttggcagtct tagcggtttc
     3481 ttgtgagatt ttttcaaggt cgtctacttt ttgcacggct tcgcccattg caatttcgac
     3541 gtaagcagtc tttttaaact cctctaaagc agcctcgata atttctgcat cattagctgt
     3601 tctcaagtct tttttgacct tctctgagat gactgcacct ctgtcatctg taataattac
     3661 ctgtgtatca acgactgctc ctgtaccgtc ccactgtggg tagtttcctg ttactttcca
     3721 atttctcatg tttatttacc ttcttccttc ggtgctgttg cttcatccaa ttgtgcgttt
     3781 aattcttcca attcgatttc atgctgtgct tttaattgag cattttccag cgttaaatta
     3841 gcgactttaa gtgttaaatc gttaataatt tttcctaata atttttcttg cattgtttct
     3901 cctaaattcc agtcatataa ttgctatgct cgttcatgat agcgctagta aaattcgggt
     3961 gtgtagtatc ccagccaaca ttttgtagat gtttccagca ccttgccaaa gctacaatcg
     4021 cataatacat tttattgata tccacaagtg tgtttacacc cgttggtgtc attttaaatc
     4081 cacggtttat accaaagtca tccgcaaaaa tgatggtatc tccataaatt tctgcctgat
     4141 caactgatgc tgtatgttca tatccgctag ccgtccgaaa aaaccttgct ccacaaaaac
     4201 gaccagatga cgcgctattg ataccatcac cagatgaagt gattccgatt gacgcataaa
     4261 gagccgacct tgtaaagttt tttggtgtcg cattaccaaa atgcacaaaa gcagtgtggg
     4321 tacctgattt tcgaacaagc gcattattgt tgctgttgaa attgatggat gcatcgctat
     4381 taaaatcgat ggtagagttg tttaaatcaa tcatcatagc accatttctt gctctgatga
     4441 ctttaccctc aagcaaactt gtaatcgtat gctcaatcct tgctttaata aagttagcat
     4501 ctaaaccaac aatgctgcta gcgttgagat taatcacatt gattttgttt gcatcgattg
     4561 tcccaccgat aatctggtcg gcttttagct tgataaactc accaagtttt gcgccaaacg
     4621 ctccattaac cgtggtattg ccgtctaagg cgatacgctc gccagagatg cggacaccgt
     4681 agccgtttaa attaatggct gagacaatct cacttgcgga cattttgctt tgcgggagtt
     4741 tgcccttaat cgcaagcata atactgtcgc ctgccccacg aatataactc tccatttcac
     4801 cacgagtgac tttttgttca atcaagccag ctagttgtgt gacacgggat tctaaccctc
     4861 ggttaggggc gctgacagtt gattgtaacc ctctaactgt ctgggttaag ctactgtaat
     4921 tcttctcagt atcctgcaat cgccgctgat agctagctag gtcctgttgc acacgactaa
     4981 cagcaccctc acgattttta atctcttgtg agatttggta ggcagttgat tgttgcgttg
     5041 attgcaaccc actgattctt gactctagca ctgtccgcat gccttgatgg ctacgagtaa
     5101 actcagctcg taagtccgca agcttactct cgtaggcctc tgtggtgccg ctagatgtcg
     5161 tggttatctt agcagataac tgctgtatct catcatcata cttttgcgac aaaccttgag
     5221 cggttgcttg tatcacagct tttaggtcgt ttttatcatt ggccattgtg gcctttaggc
     5281 cgttaatgcc agcttgataa gttgatgata gctgtctatc agcgtcttga tagtcacgtc
     5341 taatacctga gactgtctca ttaataagcg caagtttttt atcagtatcc tcactaatcc
     5401 gtgttgctat accatttgca ctttcgacaa tctctgttgt gatgttatca cgatgatact
     5461 cacgcaacat gccgtttgtt gtgagtttga tttttgccca aagctgagaa ttaacggtat
     5521 ctgtcagctc taaattaagc tcttttaact gactgagcgc tccttccaag tttttaaaaa
     5581 gtccggttga ctcaccgctg ccctcaacaa ccactggcgc cacgtagtta gttggcttac
     5641 cccctcgctc aatcatgagc tggttaaagc gagtcgtacc gatacatttg ttattagcta
     5701 atttaacgct ttttgtgtca ccatcagctt taaatgtata ataagcacgt ccgtcagagc
     5761 caatcgttaa atttgactcg tctattaaaa gtgttggatc tctactcaat tgttacctcc
     5821 taatgttgcg aaattttaaa tgttgggttt ttatacttgt ctatcccatc aaacggataa
     5881 gtccacgtct cgatagacag cattgcgcct ccgccggcaa ctgtccgaac tggtttttgt
     5941 agcttagcaa cgattttgcc gtcaacctca acagcgactt tatcaactcg atgccaaaca
     6001 accccataag tcgcaaaatc ctgattgtaa tcaatgacag cataatcatt taatttagat
     6061 acgttagcgt ctacatacgc tgtaatgttg taaacttcct gaggctctgc tgattgagac
     6121 caaatgacct gattattaca aataacgcga gctattggca gtccatcaat agtaatcgat
     6181 tggtacaaac ccatcgcggc agaaggcttt tggacgctag tatctggttt tgataatgac
     6241 tgatagttat acttattagc tttatacaca tcagcctgtg tgctagatat aattttatat
     6301 acatcaacgt cttgatctgt gtaaaagcta tagtaatcat ctatcttaat ataaaattgg
     6361 tcgacaacca aactggcttt ttgtaataaa gtaccatcaa tgctttgact gtctaagcgg
     6421 taaaaatacg tgtctggtat ctcttgcact gccattactt acctccagag cgttcaaaaa
     6481 caattaatcc gcttgtgtta tatggcactt tacctttatc aaccacacgg acagataggt
     6541 actgacctgt tgccacatct tttagctttc cgatgttgtt taactgatac tggatatcag
     6601 ctaatctaac atagccgctt agctgcgcat ttcggacaac gtccctaata tctgattgct
     6661 taacaatgtc ttgtggcaga tcagtttgtt taaggtattc atctatacca tcaatatcag
     6721 atgttctgtg ccggtgatat gtacttgctt tgttttgtag ctctatttta gtcgcatacc
     6781 ggtctaggtt tagatcagta atatcactta gcgagtgctt gtgacttgct ttagcataag
     6841 tgctgtttgc ctctgcttta gacagatagt ctgcaagctg cttactcaca tcaatctctt
     6901 taagttctgc ctttgtagcg taggcagata ggtctacgtc cttagcttta atttgggcga
     6961 tttggtcaga agtaaggtct tcaaacttta aggaatcacc cttatcacct ttttgacctt
     7021 tgatgttgcc tactaacttt tcagattctt cttcaaactt gacaaaaagg ttcccctctt
     7081 catcaactcg agcactctct actccttttc ctctatcccc tttttggcca ttagggatac
     7141 taaaggtttt ttgagtgtca tctgatagtg tgatagtaag cgtctcaccc actttagtga
     7201 tgtcggcaat acttgtccct ttatcacctt tttgaccttt gatgttgcca agcttagtct
     7261 ctttgtcgcc aatccacaca gacaagtcac cattttcgga tagctgtact ttagtgatag
     7321 attctccttg aggaccttcg tagtaaggca agtcgttgta attcaatttg ccatctccga
     7381 cctttagcct gtgagtgtct agctcaacaa ctagttcacc atcatcaaca acaggattta
     7441 atttttgcca ttcggcggca tccttgcggt caaataagac tttaattggt attctttctt
     7501 ctagcgtcat ctgtccctcc ttccgtctaa aataattttt ggattgcttg attgtttagc
     7561 tgtgattgtt gcacctttag catcaaccac agctttataa gccatatcca gagctaaaat
     7621 ttgcccctct gacgcggtta aatctatttg cttagattta taccaatcac ctgttaaaac
     7681 acctttatag ctcaaaggat agacctctat agactgttta tccttagtga cctcaaacgt
     7741 ctgtggctcc atcttagcct ttgtcggtgt cagcaccagc ttgagacctt tattattagc
     7801 ctgtatcagc gtaattgcca ctttatttag tggctcacat gtctggctaa agctaatcgt
     7861 ataggtctcg ccacgcttga aaccaccatc attggcttct acctcaataa aatcctcatc
     7921 aattttttta acacgattag ggttgccgac cagcaaattt ttgttgtagc gggtcttacc
     7981 gtctgtgcct atgatttcgg cgtttagacg ggatgtctcg ctcgtttcac tgactttgtt
     8041 tttgaggtcg tcaaagcttt gtttaatcga tgggatgtca tcaaccttga tagcatctgt
     8101 gattttttta atggcttctt ctggtaacgc taggtttttg agtgtttctc taaactcttc
     8161 aagctctttg tcagtgcgcc ggttgatttc ttcttgcgct tttttggctt tttcgattgc
     8221 ctcagagatt tgtttttcga ggtcttcacg ccatcgttct gggtcgttca caacctcggg
     8281 ttcctcccac tcagcaccat tccaaaagta cattctagta gtatcaccaa cttttagaaa
     8341 taatatgtct ccttttttta aggttccttt tggttcatct ttgggcattt ctgtgccacc
     8401 gtaaacagta tttttcccat cagcagatac tagtgcttgt gttgctactt caattgcaga
     8461 agcaatatct gcatctatct gattgattct actgtttata gacagacttc ctacgctttg
     8521 ttttttcaca gatccgatat cattacaagt gacttcatgt tttactaaag ctccagttgc
     8581 gtcgtagtag cttgtaaaag aaactatccg tatacgctct tgaaaaccta aagtctcatt
     8641 tatcgccata atgtagtcac cagcaaccgg cctctcacat ctataaccag ctctcattaa
     8701 atcttccata tcaattttta ctgatatctt ataagaattt tcaacattac tttttaaagc
     8761 ttcttttaga ttatctgcca ccgtgaagcg ctcatccgtc agaggcgccc cttcaagtcg
     8821 accgtactcc ttggcaagag ggctttcgta ttccgcctca agtctcccct tagagtggtc
     8881 ctctgggtcg gtccatgcac caaagccttt ctgataggta ataaagctat caatattttt
     8941 ttcaatggta agatcattca tgttgaaatt ttttcgtacc actgttgaca gatcagtacc
     9001 tatgtttttt aatagccgaa caactttccc gctgactgaa aactcaagtc cggtcgcttt
     9061 aataatctca ttgaataaat ctaacctaga cttataatta aaagattgtt ttctaaatgc
     9121 gttcacacct acttctagct tatagcggta cccactacct ttaaatactg tctctagata
     9181 ggtatcaatg gtatgagacc catctccgag accctcatag atactactct tgctgaagtc
     9241 ccaaaaaaat tggtgtatgg catcaaacga aacttgcgtt ttttgaccaa catcaacagg
     9301 ctttgcgtaa ataacaacgt aatactcatc ttcaaatcta agtcgccacc ctctatcgat
     9361 attattgagg acatcactgt ttgtataaat ttccccgctc actgagcgct caccattaac
     9421 agcattagta tgcctaatga cactaatggc cccatactca atgtcacgat gatccaaaaa
     9481 agtaatcatt agaccctcct atttatacaa ctctacaaaa tttaaaatcc taatcgtgcc
     9541 aagaaaatcc gttttgtaag taattctctt gttaggatta ggattgaaga taaaatactc
     9601 atagttcgtt ttagcattga cataatttcc gtttagtgtg gtagctatgc ctgtcaaaag
     9661 taatttatca ctattttgta gctggctatt ctgcttaaac tcaaagcgcc tgccatcaat
     9721 ttcaatataa aaattagtct gacctccaga gggagtaagc tctataataa aaggccactc
     9781 taactgactt gctttagcgg ttcctccata ggcaaaactg ccccctgata gagttatgtc
     9841 ctttggtttt gtctcaccga aaggtaattc agcagttctt agtgtgaagg aaagattata
     9901 ttttagtcct tgactggttt ttcctataaa ttcataagcg atagtgtcgt ctaggatgac
     9961 tttaaatcta tatttccaag gtttatgagg agagccaata agttgcaggt ctcctgtgct
    10021 ttcccctgga agctcaaagt taaatagatc tgagttttca gggtacatct tagtcacgta
    10081 gaaaggttcg tcaacaacaa gcagagcgtt tagttcgtcc tgtttgtcca aaactccttc
    10141 tacatcgctt accgtcactc ttcctttgac cttaagcgtt ttagtcgtaa aagtagcccc
    10201 atcgtagatg taaccactcc ttcctttgac tgctcggtgt gatacagata gtagaggagc
    10261 actatcttca atagcaatat tataaatacc aaagtcagac aatctagttg cctgactctc
    10321 tttttctatt aataaatcca aaatactccc ttctaggcaa aaacaaaata agaatcttta
    10381 gattgctctc ttgattcttt ttctttaaca gccgtgtaaa ttttatctcc aacaatctca
    10441 ttatgcactt caaagatagg ctctgacaat tgagactgcc taacctcttc gctaagatta
    10501 tcaagagagg tattgattcc actattatta actttagcag atgttgaaac agtactattt
    10561 accccccagt tttgatcagt aactgctgtt gcgtatgctt tacctagact attgatctca
    10621 cctatccact ctgccatacc gagggcaaac ccctctccag taaatgctcc tagtgtttta
    10681 gtgacacgag atggcgagtg aatatccaga gcgcgtctaa ttgttgctgc tacgttagcg
    10741 gcaatgctgt tagctattgc gtagattgtg cctgcgctac tagctagacc attagcaaaa
    10801 ccttgacctg cataagctcc tgcagaagac atctgccctg ccaaagccct gaatattgag
    10861 aggatcttct gacaagcatt attagacacc gcggttgcac gagacatccc agaagtcact
    10921 gaacttacaa ggtttgccat agattgcttt gcagtactgt taatgctact aaatcctgtt
    10981 ttaaccgcat tggctatccc attcattgag gttgttgctg aagtcttcgc cttattgaag
    11041 ccagactcaa ccgccgagga caacctattg gcgcttgagg ttgcagaggt tgctgcagaa
    11101 gacatttcac ttgtcacgct attagacaga ccagaggctg ctttagttga gtttgactgc
    11161 attgatgcca gactgttact cactcctgag ctcatagctt gcgcctgaga agttgcactt
    11221 gtgctagcgg ttcccatgtt tgcaccaaca ccactagcta agctgagcgt atgattaatg
    11281 gcgtctagat tcattgaaga agtcgcacca ttaacccctg aagccatttc ttgagcctga
    11341 gtagtagcgt taatattagc cacagacata ttagcgctaa tgccactcgc aagagacatt
    11401 gaatcattca acccctgaag actcatcgtt cctgtctgag cattaacatt attagccatc
    11461 tgtgtagcat ttgatgtagc gtttatatta gcaagctctg tattttgact aatgctatta
    11521 agcatagatg tcgtatctgt attggcttga ttagccatag ctgttgtttg agtaccaaca
    11581 ttcaaggcca tggccgtggc gtccgcagag actttagctg tacttgtgga actcttacct
    11641 gtgatttgat cccacatcga actgaatccg ctcttaatac cttcccaaac tcctgaaaga
    11701 gcatttggga tagcctctaa catggcttta ccgagtcccg taattaattg aatacccgca
    11761 gaaataatct gtggaagtcc ctttatcaag gctacggcta gttgtacaac aagctgaatg
    11821 cccgctgcga taatctgagg cagagcttgc gtcagtccag aaactaaaga ctgtataatc
    11881 tgtacagcag attgtacaat ctggggtaga ttttgaataa tcccctgcac aaggctaata
    11941 atgatttgaa tgccaccttg aagtaactgc ggtaaaaact gtacaattcc agatacaaaa
    12001 ctcgtaataa cttgagtagc tatctgcaga acagttggca acatttgagt aattccctgt
    12061 acaagattca ccaaaatagc tataccgtgg ctgataatac taggaaggtt agcctgtaaa
    12121 ctgttcccaa aactaccaat gatttgctgt gcttgctgga taataagagg tatattttga
    12181 actatgccgt tgacaacatt taataatagc tccattccaa cagaaataag ctgcggcaag
    12241 gcactcgcaa ttgagctaac aaaactacca atgattttta ttgctgaact aattaaactc
    12301 gttgcatttt gtccaatacc ttggacgaga ctggtaatta gctgaacgcc agcttgaatt
    12361 ataaccggta ataacactgt gatagcattt gcaaatttag caatcaattg agtaccacta
    12421 gctatcaaag ctggtatttt agaagtaatc ccttttacaa ggccttgaat aatgctaggg
    12481 ccttttgtta cagcagtgtt aagtagctgg tcgatttgtg cgccaaactg gctattaatc
    12541 aaaccaagtc ctgccaccac aagtcctagg atagcggccg gtcctatggc cgccagtgct
    12601 aaactcacaa gactggacat tgcgcttgtc atagttccaa gcacagatag cccacgccct
    12661 gctgcggtag caaaaacgcc aggtaatccg cttagagttg ccgcaaaggc accaacaacg
    12721 ccgctggcac tagctatccc actagaaatt atgccgccaa acaccccgac agaagcccct
    12781 aagcttccta aagctagacc aacttttcca aatagagaaa gcaaaggcat tatcgttgct
    12841 atagcgctag cggggttcat cactgcccaa agggcaatga ccttaggggc taaagaagtg
    12901 atttttgctt ttagattatc aaaagcctgc cctgataatt caccagtatg tgcaaaatct
    12961 ccaagaacag tattaataag agcaaacacc tctttaacgc tggcgcctaa tgggctaaag
    13021 tcaatattga tagactgttt tagcctagcg aatgctgcaa ctgcatttgg aataagagaa
    13081 ttaatcgtat caaaaacgct ggttattgcg ggcttcaggc taagaagtgt ttcagcaatg
    13141 gtcttcatac cattagcttt agccgcttca tcaaaggctg aaatcatacc tgctacgcct
    13201 tttacaacgg cggtatgtac gttcttccac gcagttcgga ttccaccagc cgatgattgg
    13261 gccatctctg caaatccgcc ttgggcatcg ttaagctcaa tcattttatc tgcgaactct
    13321 tgtgcagtga ttttgccatc agataaggct gattttaaat cttgtacgcc atttttacca
    13381 aaaccgaagg cttccgccat tttagacatt aaacctggcg cagcttctga tacagagtta
    13441 aactcttcag cttgaatttt tccagacccc aacgactggt taaactgcct gagtgcttgc
    13501 tcagcccctt cagttgttgc cccgtaaccg atcattgcgt tattgaaggc gagggctaaa
    13561 ctagtccctt tatctaaact tcctgtggtt atggcgagct gttgagcgct ttttacagca
    13621 ctgtctagag gagttggcag accttcaatt ccttttgata gcttatcaat tgatgcctta
    13681 gattgttcag cagaataccc aaatagcgcc atcgttttcg gaaagcggtt catggtatca
    13741 acgcgactaa ccgccccgtc tattgcccca gtaatagcgt gcatagcttt ttgaacaaca
    13801 gccattaaac taaaggcctg cacgatgctc atcactgtac ttttgagtct ctctccagca
    13861 gaagaggtgt tggcgaattt ctggctgatt ccattcaagg aagtagccgc agaactagac
    13921 attctgctaa aaccattgct aagactactc cctattttac ttgataaatt agctaaactt
    13981 gaggtcagcc gaccaaacaa actagtactc actttgtttg cgaaagcaga cgccttagct
    14041 gatacagaac taaaaaaatt attccatgac tgtaaggctg ggttcaagac ttgccgacca
    14101 agtgaattag aaatcttccc tccaacagac tgtatagagc tattcagggt agaaacggat
    14161 gaggcaattt ttctaaacgc tgttccgaat ggtcgcggaa gcttgcctgc gaccgtttcg
    14221 aatattgcag ataagttatt aagcttacta cttgccctct gagttaagat atcaactcca
    14281 gtcgcagcct tggcaaatgc agatcttatc ttaccaatat ccacaagatt ctgaagttgc
    14341 atttttgttt gattaatgaa accggttaag ttaccccgta ttttgtcaat aacacttgca
    14401 actggaataa tgattttttg aaaaccattc tttatgggtt cgggaatttt ttcgccaatg
    14461 gaagctgcta tgcgttgaat ttcaccaata ctcagtttta aaccagtagc gtaggcggaa
    14521 ccaagtctct ttccgagcga ttcgccgttg ttcgctaatt gggccatgat ttgtccaatg
    14581 atttgaacca ttttattact actgttaacc gctgtatctt gggcttttct gaaagcattc
    14641 tgagtcgtac taacaatacg agccatggcc tgctcatagt cctttgtgtt ggcaccaata
    14701 tcagcaaaaa tagaaccatc aaacgttcct ggcatctact cctccttatc tatctatttt
    14761 gaaaatgatt attaagcatt tgtattctct caacaatact gctatcacta tcggcttggc
    14821 tacggctagc tttttgatac gatcttttga tagttagcct atgcttatcg tatttgagct
    14881 tacctacatc aaccttttta gcatttaatg tatatctaag ttttagagac aattcagaga
    14941 ggttctcgcg ctcagcaacc tgcttatact caagcccctc cataatagcc tctagctccc
    15001 acttagtaca tttatagata gtatcaatgt ctgtgagccc taaccgtgcg caatttacta
    15061 agatactgcg ttgctcattc ttccaatcat gtcttcgata atttggattt gagttgcgtc
    15121 cgtgtcgtcc ttcgctttga gataacgagc tgatttctcc atgttttcga tatatttcaa
    15181 aatcttcgct ctgaaaaaac cagaatcaac catttctttc tctatttcag caaacaaccc
    15241 ttctgttgtt ccttcttcat caacagcttc tgcaattgca tctagaattt catcttcagt
    15301 tagcgctttt tttccgcttc ccgcagataa acgcacaagg tcaacaatgg cgctttcatt
    15361 acgctctaag atattgaaaa acaaagcacc aacaccatct gcattgcgct ctcctgtttc
    15421 tgggttaatt gttcctagtt tattattgat cttaaacata gttttaaaat caaatttaat
    15481 atcgatattt cgtttcgctg ctgtaaattc cattatttta tctccttttt aaatcaaaat
    15541 ggggcagcag ttgccgcccc tgtgtactac ttagtgatat tatcgtagtc gccagtagta
    15601 tcacccggat tttgatagcc gtatacgttt tctagcattt caatttcttc tttcgtgaga
    15661 gggaatttac catcttgtaa ggcccctaca atgttagcgg tgtaggacat ttctactaag
    15721 tctgaaatac cagtaccgcg ttcgatttcg tcaatcttgg cgtacccaaa cttagcaggg
    15781 taaacatctt tcttgggtcc agccgattca gaaatttgga tctgttcttt gacactttcg
    15841 tcggcaatga cttcccaaat tttgatagat ttacctgttt tcttagcttc ctcgatgaca
    15901 gcaacagatg gatctgtcgg tacaaagtac gttgtcaaat caatagagtg ttcatctgta
    15961 gccttctcaa taacgcggcc ttgttgggtt tgctcatcaa tgtattcacc gcccatggtt
    16021 gtagtaccat cggtacgata ggctggcagc aaagccttgc tacctttttt agcatcaact
    16081 gattggatga aataaaaaat ctttttccct acaatcggtt tacctgttgt aatttcaata
    16141 gttgttcctt ctttagtgtt tgccatttag gtctccttta aaatagtgtt tctgtaatgt
    16201 tgatagcaac tctatagact tctcgtccta ttgaattatc taccaaaatc tgagccttta
    16261 tttggttatt ccgcccaagt agtctaagca ggcgagcttt aatctcttct gcatccaaac
    16321 gactatcgcc aggtaagaaa gcatcgatat tcaggctaaa atcgtcaata actgctccag
    16381 tttgagctgt ttttgacaag tctgatatat ttgtacctac aacaataaaa ggctctaaaa
    16441 cgtctgattt aggcaattta aaatagattg gtatgcctaa agctcccaat ctatttttta
    16501 ccttttttaa atatagtgtt tctggtgagt aatccatgca tcacctctta aacatttttt
    16561 tgagattagc cattagcaca ggccattctt ttctcagggc agggtctaaa aacggttgag
    16621 cttccatttt acgagtacct aattcaagat aaatagaata taaagcagga gaaaccactc
    16681 tatagtgtaa gagtcgttgt tgctcattgt agatttgagc tctcagccat ccagtatcaa
    16741 ccggggctag tattttagcc tgtctctcaa tcctagcagc tgatttacta agctctttat
    16801 ctacagcgat tcgtactgac ttctgcttgc gctcaacgct gcgtaaaaac ctatctaggc
    16861 ctctcatccg ataaataaga ctcatacata aataaccgtg ctatttttat ggtgtgctag
    16921 tccctttatc aacctcggtt ttcccttgta gataatcttg ctaaagccgt cgtaatggcc
    16981 ttgcaagtgc aacttaaaag cattcaaatc atatttacca aatagcccca tctgttcaga
    17041 ttttgtgaaa gtattttcca tgcaggggat tttcccgcta ggtttttcaa cagttctttt
    17101 atctagaaaa tcgtcctgct catcgacata cactaagatt actctatctt tatagatcat
    17161 tgtgtatctc ctaaataaat cttgctaccc ctttgcctga atataccttc ccaatagcag
    17221 cgcttctgag tgttgattca tactctttaa ggtaactgtc ccacttaaaa gtctttcctt
    17281 cttcgctatc ttcaacggtt ccttctgaat taatcctatt aaaccgttta atagcaacat
    17341 cacggacaat aaacctcaat ctatcaggaa ttttggtgat ttcagtttct gagtattcat
    17401 taagtttagc tagcacacgc tctttacttt cagatatagc aagggtgatg agctcatctt
    17461 gcgcaccatc atccttggaa atacctataa agagtttgat atcgtcaata agttgtttat
    17521 cgcccatata aatagccttt aaccaccaat gccgggtaca gcagcagctt cgattgttgc
    17581 ctctacaacc ccttcaggaa tttcagcaaa cagcacattt gccccaaaga aaacagattc
    17641 ataggtaaga ttagaaagct gacgattacg agctgcagca attaaacctg tctcatcagt
    17701 aaaatcagca aacaaaccac ccaagtctcc gcctttaaca tttaaagatg caaaaactag
    17761 attctctaca gccgttgagt agattttacc ctctggcaca gatggcataa caatcacgtt
    17821 ttgcataccc aaaaagttct taagcaatgt cattccaaaa acattagaag catccgcacc
    17881 tactttagta tctccaagat agttggctac gtctaaagga gagacaaaag aaacaagcgg
    17941 ggaaccctca aactcattaa aagtagctag cttagcccat gatgcagaca gcgctttttg
    18001 aaggccaacg cctttaactt ttgttggttt tgttttgagg aatgtaaaga atgcatcctt
    18061 aattccattc tgaagctcac gcataatgcg cttatctgct tcagtaatag cacgagctgc
    18121 gccatggcga gcaattgact cagctgtagt tgcacgacgt ttcttgaacc acttcactgt
    18181 atagtcttta tctttagttc gagtaacctt agacagaggg atggtttccc cttctccagg
    18241 atcagtttga tctaaagtca cttcccactt ataggtctga atttttagat cgttagttaa
    18301 tgtttcacga cgagtaaccc ctagcaattt tagtaaatca ttaatatttt tggaaaactt
    18361 gttaacaaaa tcaattgatt taatatctcc taagtccgcc atagtgttta aatttttttc
    18421 agccataata ttcctctctt aaaataagtt acgattctca gcaattaaac gcatacgttc
    18481 gtcatcatcc tctattgcca tgatgtcagc cttagtcata ccgaccgagc cgtttccagt
    18541 tcgtggtggc ttctgggtta aacgatcgtt aacacgtttt tcgacagctt tatcaaaaat
    18601 agtttgtaaa ttatcaatat tggccttaac ctcttctgca gtagtggtta aaacaatatc
    18661 aataaaatcc aatggcaatc ctttctccac aagcagggaa tgcgtttcaa tgcgcatctc
    18721 gcgctctgct actgcttttt cacgctctgc gatagcatct agacgttttt gttcctcctc
    18781 tttagcgcgc tcatcttttg acaacttggc caaacgttca ccctctgtac gagctttttc
    18841 aatagcttct gattgttcag attcccattt agtgcgttcg gcagccatca tttttgagat
    18901 gtctgcgcga gtaaaagttc gctcatgttc ctgcttagga tgttcaacag cttctttttg
    18961 agtgtcgact tgctcagttg tttctgttgt tacattctct tctgccataa ctttctccta
    19021 gtggttacgc caccaaccga tagtctagct ttacgtcctg cgacgaaaca gtgtagcttt
    19081 tagtgtcatc aacaaagttt ggacacaata aaagccgtat tgctacgact ttgatttcta
    19141 aaggggtcga attcgtttaa aatttatttt ccccacttac gcttataatt tttcttaatg
    19201 tagttaacat caattgcaat gtttgtaata gctgcttgat tatctaaagt agcagcttta
    19261 acagacgcaa actcttcgtt tgttgccaga gcgttccgct gaacaattga tttcaactcc
    19321 atgatttctt tgttttgatt tttaattgct tctgcttgca tggcattctc tgcaacaagc
    19381 atcacaacca ctgtttccaa tttacgtttt ttcttaatgc gcttattcat gtttatccta
    19441 cctttttcaa ttctgcaata attgacttaa ccgctattgc tgcaatgcca acaatcaata
    19501 tgagcaccaa tacacctagt gccactaata ccatttgcca aataaacata ttttcctcct
    19561 tgatagtttt aatagggtga tgtataattg agataaagaa ggatgatggt ctaacgccca
    19621 cgaagcagtt tactgtggag gcggtggggc atcatccttc tttttctaat acagctaata
    19681 cctcatcttt atttttgata attgatatat caagacccct acgatctatc atataaattt
    19741 gttctaactg ccccattatc tcttcaaatg ataaaggggt ttttgttata tcaaaaatga
    19801 tattagttgc ctgctttttt gcttttcgta gattgccatc aatgacgttt ttacccgaac
    19861 ctgtgatttc ttttagatca aaaggaactc tatcaactaa ataatcagga gtattgatat
    19921 gttcagggga attaactctt ggcaccatgt caacttgcaa tcctgtcttt ttagataacc
    19981 aattagcaac tctatattca taattcgagt gatcaagaac aacattatgg ccatctactt
    20041 tgtaaggagt gccatttttt acatactcat ttagtagtga cagttgtggt ttatgcccat
    20101 ttccatctat ccaatctgag gtgacatcct taaaatactt agtgctttta tcatcaattg
    20161 gttctacttc aatgcttagc tcatcttcat caggaataag ggttgttctg cagttgaaat
    20221 gataaggtgc tgcattaatt ccaggcttta gctcagataa tagctttctt ttgttttctt
    20281 tagcgatttt acgacatatc tcagttgtcc tgtcatcacg cctaactaaa tcacgataat
    20341 acttaagacc tgcatccaag tagcgcctag cggtagcatt attaatcacc atagttccat
    20401 cagttctgat tagtgtttca gccctgtgat tggcaacatt aaattgctta gctaaatctc
    20461 tggctatcgc cctaggatgc tcgccacgaa caaaaccttg ttttaatttc ttttggagat
    20521 tcttgacaag attgtcagta ttgccccaca gctgttctga atagttataa ccatcaaacg
    20581 gggttctaac cagttcttct aaaactggac cattgattgt ccctgaccgt ccacccattg
    20641 cttttttata agcatatgag gcagcttttt ttaaatgatt ttcaaatgct gaatcaagta
    20701 caccttttag tatccctgcg cgataaacaa gttcaagatt taatgcatcc atccttgtag
    20761 ctcttgctga tacatactgc tcattaagtc gttttagcag ctcagggtct ttctcagctt
    20821 gtttgcgata cttgttagca ttagctacgt aatctgataa atcttcatga cgtagctttt
    20881 taacgacatc ctgataagtc attttgttct cttcagaata cttagtataa aaatcaaaca
    20941 attccttttg taactcaaaa gcctgttcat tatataactt ctgcagttct gaaaagacat
    21001 ctaaatcagc tctgtctaaa taacttagaa tatcttcttg acgcttttgc cagtaattaa
    21061 ggcttttctg ctgttggttc ttcttgacca ctagcatcac ctaccaatct aggctccggt
    21121 aaagattgct ttttatcagc ttcttctttc aaacgttcaa gctctgcttc agcgtctact
    21181 cctgtgacag tgtttaagat ttcaaagata gtctgatcgc taacaatgcc ataaagattt
    21241 tgtgcagctg taacaatttc attatcgttt tgaggaagat taggtgtgaa aactatactc
    21301 gtatcattta caaggctata tgtagttgct tcattccctt tgatggccca gatattagct
    21361 gctaagcgta agcgccgcat taagcctttt ttgaacaacc tctcttgctt ctcgcgatag
    21421 ttgtcagaag ccataagctt atacttcatt gattcaccag attgaactcc tgaaaatttc
    21481 atatcttgtg tatctggcgt aaaagtaaac ctcaaaatgt ctgcaactag tctatttttg
    21541 taggcttcgc taccggcggt atcatactct tttttgagaa agtacgcttg tggtttaacg
    21601 ccatttggat taggattatc gtctaaaatt aacacttggg cttttttaaa cccaattgag
    21661 atcgctaaac gaccattagg atttaatcgt ccgtcatcta agtagtcatt ctcatcagcc
    21721 cctgtgtaag cattaccagc tattacaagc aacgcattga ctgaatcttg ttgaaaatta
    21781 gcaagctcgg actgagataa atcataggca tcaatattat caagtacaga ctcataagcc
    21841 cctgtacgct cctcattatt agcatattca ttgactggta cacctttaaa aaaatgttct
    21901 tcatgctctt ttaagcacgt accttttgtt tcgagattat agtcttcgta ggtgtaaatt
    21961 gtgtcggaag tatatacttt gataatctgt ttgcgtttac ctgagccata atctatgttg
    22021 taaaaatgaa cggccatcaa cgaatttcgc tggtatgtat catcatagat aacaaaagtt
    22081 tgctcggctg ggagctggta gagttttact tcggtttttt tgtcatctat ttcctcaaca
    22141 gttaacagct cgtaggctct tccataaatt gataaatctg tttttatttt gacgttgtgg
    22201 tagtcctcat tgtttctgac cgacataagg tcaatagccg cctggaggtc tttattttca
    22261 tttttgtact caacgggaac accaagcata taaccttgct caaataccgt aatatattta
    22321 gcaaaatcac ttgcaatacg attatccgct gcgtatttat ctgttttagc aggtctatac
    22381 ttgatgttat tatccccaag atagtatcgc tttaactctt tcaaacgctc taattgttct
    22441 gctttaaacc ttgaaatgta attcttaagt tgatctatcc aaagttttga ttcatagtca
    22501 attgcttcaa agtcttcttg cagcataata aattgcttat tagcattctc attaaaacga
    22561 gttcctgcta aaaattgttt ttcttccaaa gtctcacctc attcctaaaa ataatattta
    22621 gcatttttca tgcgcttact tctatccgcc gactggtata ttctgtcttg tacggcatat
    22681 cttatggcgt caatgcagtg gttataactg tcaactggtt cgttgatata ctcattagtt
    22741 ttcttgtctt tcttccaagt gtaattttcg agttcttcaa tagtcttgac acacctttca
    22801 tcaacaaccc aatcatactg aagcaggtac tgaattcctt gcataacggt tccaggccct
    22861 tttgtaacat caatcattct aggaatacct aaattcctca gctcttggtt agatttcttt
    22921 tcagccgaat ctcctctgat ttcttctttg gcatagccga ggtcctttat agcatttgct
    22981 attttgtcat tggtcaaatt ctttctgaca tattcctcta tgacgtataa cttcttgttt
    23041 gcgtcatcga ttttaacatg caaaaatgcc gaagggtcat tgataaaccc atagtccaaa
    23101 ccaaaaaaag aagacaagtg tgataacttg tctttgttta atatttgctt gtcatatttg
    23161 ggaaaaatta gtttatcaag tgtagcaaac tggccaagag catatatttt gtagtaagct
    23221 tcattcctat cggctagttc ctcaatattt tctctcgtga catcatctaa gaagcggttg
    23281 tctttataag ttgtttgata gacaactgta ttcttaggtg tcttaacgaa gaaggcttta
    23341 taaacccagt ttacttttga cacagggtta aacatcaagt atatttgctt ctctagatgt
    23401 ttcttatctc ttaaacgcaa agtcaactgc gtataatcat caagcgtaaa ctcactagct
    23461 tcttccatga cgacatcaga tatcccctta attgacttaa tcttctcagg gttatccata
    23521 cccttaaaaa tgaattccga gccattcggg agcgttattc taaaagccga catatttatc
    23581 ttacatttat ccaagatgcc gaaatacgac aaattagaca tgatatcagc aaatacagag
    23641 tctctaacgg ttgcaccgac ttttctgaga actaatatct ttctgggatg tttgaattta
    23701 gggttaagtg cttttaaaat tatcttttga aaaacaccgt gagactttcc gctagacgcc
    23761 ccaccataat gaacttccgt gaagttgcta tagttgtaaa gtttgtcgta gatatgtttg
    23821 ttaaaaactt tgctaggata cttgattacg atattaattt tagggcgctg tttaatcgtc
    23881 atcccactca cctacgttaa tggttacatc tgagctgaca tccatttcaa ccttgtcagt
    23941 gaataatctg taccgcttac ctagtagctc agctgccttg attctatctt ttgcaccaac
    24001 atcgatgtca actatcttct ggccaaactc tccaacgcta atgagcgtct tttcttgttg
    24061 gtctcctcgc ataattgaag tgagatattg taggacttct tcttgcgtag caatcttttc
    24121 agattcaagt ttttcaagcc gctcgtctat ataagcttta atgtcaggtt tggtcaagtt
    24181 ttcttgacct attgaccttg ctgtcttttt actataccct gctttaatag cagctgctgt
    24241 cgcgttagct gagatgatgt actcatctgc aaaacgcttc tgttttaggg ttaatttact
    24301 caattttcca tcacctccaa gcataacaaa aaggcaagac actatttgcc ttacctttaa
    24361 actcatacta tcaatttatc atcaaaaaga tgacaattcc atacattttt gtgtcacatt
    24421 cctatttttt tggagaatat ttctagaatc cgctctcttt tgcggtaaat agacttacgt
    24481 gacagatgtc ttgtataggc aatttcttcc caagtgttac ttgaaccaac accccaccta
    24541 agattaaaaa tatcagttag ctcttcatcc aaaagattta gcgttgcaat aactgcttct
    24601 ttgaaattgg atagaccctt tagttcccta tctgaatccc accttgcaac cacatcctca
    24661 gtaacttttg aaacaaaatt tgctcttcct ccaccgatat ttttatctac ttctgtattc
    24721 atatcagttt gtagctcaag ttttcgaagt gcaatcttgt tatcaataaa acgataatca
    24781 aacaaccatt catcaaaagc ctttagctgt gcattagata atctactcat cccgttacct
    24841 ctttatgaat aattacgtga gaaatatttt gtttgggtat aataactgcg ttgttttttc
    24901 catttagagc aatgacatcg ttatttttca ttgcgccaat tacttcatca atacaaattt
    24961 caccataatt agaaacgctc ttagtaggac cttgctttaa aaaaaattca attttcattt
    25021 gctacctcca taagattttc accgcaaaaa ggacagtgtt tctgactata tgtttcattt
    25081 ttacactctg gacaacatgg tactgcataa gttgttaaat cacctacagc atctatcccg
    25141 ttttccattc tatggattat attcatacct acccccccat ttcctgtcaa ttctgcaatc
    25201 cgtttgtttg cgatattaaa gtaatcttta tttagctcat atccaataaa gtctctcccc
    25261 gtcagtagac aagctactcc tgttgatccg ctgcccataa aaggatctag gacaacagcc
    25321 ccttttgttg tgtgtcgcgt aatgatgtcc ttcatcagag ctactggctt ttgtgtcgga
    25381 tgctgtgttt tttctgctcc tgccacaact ggatatctgt attctggcct atcgtatttt
    25441 tcagatttac gattaaatac ccacttggat ttttttcgga cgacccatac cccgtactcg
    25501 ctatctgtaa tataccttct atctctgttt ctgggcatag ggttatcttt tacccaccta
    25561 aaaatatcct ttactactaa cccatttttt tcacaatgtc ttgcaatatc tcctaaattt
    25621 ttccaatcgt tgaagattat catgccaccg tttttagtta atttttgact tgcaatgtca
    25681 atccaactca gtaaatcaaa acctttatcc caatcaccaa aatctatacc tgttcgcccc
    25741 atggtagcaa agttattttt tactgatatg ttgtatggtg ggtccgttat caccatgtcg
    25801 atcaatccat cagttaactc cgctagtaat tctaagcaat ttccgcattt tatttccatg
    25861 tgttttctta ccccccattc cctgtcaatt ccgcaatccg ttttgtctgt ctagctctat
    25921 cctcactcgc acgtttaagc tgcttttgtg tcctgcttag ctgtgtccgt aatcctgtaa
    25981 tttgcggctc atagtggttt tgtaaggcta tacttatcat cagtaacata ataactgctg
    26041 tcattaagac ggcaattaca ttagactgca tatacaatct atcatctttc cgctttatct
    26101 cttctagcag cggttttatt agttcttctg tcattttttc cactccctag tatatttttc
    26161 tttaactgtt gcttcgcaag aattccaaaa cttcaacatg tccgcttttc gcgtaaaggt
    26221 tttctcttca aactgaggtt ttgcctcaaa attcttttct ctacccgtgt agattctaac
    26281 gacatattct tttttcatct agactcctaa ctgcgcctta actgcttcga gtaaggcgtt
    26341 ctgatttttt tctttgcctt gtaaaatcct aagtactttt tcatcaactg tattttctgc
    26401 aacaatgtgg tgcacaataa cgggttctgt ctgcccttgt ctatctaatc tggcattagc
    26461 ttgctgataa tattcaagac tccacgttag cccaaaccaa acaataatat gcccgccttt
    26521 ttgtagatta agcccatgcc cagctgattg agggtgacac agaagaattg gtattttccc
    26581 ggaattccac ttgtcaactg acgtcaactc ttcagcctga gggaatcgtt tcttaagtct
    26641 ttcaaaatca tgttgatact gataaaaaac taagattggc tggccttggc tttcttctac
    26701 tatgtcctca agcgcgtcaa gtttgtcatc gtgtatagca actgttgatt tatcatcatc
    26761 atagatagca ccattagcca tttgaagtaa tttattggcc aagaccgcag agttagccgc
    26821 agatatttcc ttatccttaa actccaacac caaatcagct tcaagctgtt tgtaagcttt
    26881 catattagat aacttaactg atacaacgtt gttggttcgc ggcggtaact tgagatagtc
    26941 tttagctttc atgctgacac agatgtcctc aatcttgtta tagatttctg cttctgcgcc
    27001 atccctaagc gcccaactgt aaatgattgg accattacgc ttatcaggaa caaaatactt
    27061 gtctttaaat cgagtctggc tagtctcaag cctgtcgcct ctgtccatca gataaatctg
    27121 cggccacaaa tcaatcaaac tgttaggcgc tggggttcct gttagtccta caaggcgttg
    27181 gactttcggt ctaacttttc gcaaagccct aaaccgtttt gacttactag acttaaagct
    27241 tgacagctca tcaataacca caaaggtaaa cggccattta gtcttgtagt attcaacaag
    27301 ccaggtaaca ttctcacgat taatcaaata gatatcagct tctgtttcta acgcctcaat
    27361 tcgttttccc tcgctcccca aaactttaga gtaggtgaaa tcaaaatgcc atttctcaat
    27421 ctccgtaggc cacgtttctt ccgccacttt tttaggggct acgattaaaa tcttatgatc
    27481 ctcggaaaaa atattttgaa tctcatctat cgccgatagt gttgtcagcg ttttaccaag
    27541 gcccatgtca agtaaaaggc cgcaataagg gtgctctact atccatgtct tagcgtattc
    27601 ctgatactcg tgcagtctca cacccagttc cccatttctt ttaaggccat gtccactgat
    27661 tcgtaggagt caacaaccca aacatgctgc ccagcctctt ttattttttt gtgcattgca
    27721 acttggctgg gtcttggttt tttaccaggc gctttgacct ctacaaaaaa ggttcccgta
    27781 ttcatgacaa caattctgtc aggcactcct atcgtccctg gactagtaaa ttttaaacac
    27841 agcccttttg ttttcttttt caaataattt tcaatatctt tttcagtcct catccttcct
    27901 cctttggtca ataaaggtca gggttaccgt ttttttcaac ttactttctc ttttttatat
    27961 atgtgtttt
//
LOCUS       DAUGUF010000024        27655 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUGUF010000024 DAUGUF010000000
VERSION     DAUGUF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27655
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.024"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(207..668)
                     /locus_tag="VIB71_001108"
     CDS             complement(207..668)
                     /locus_tag="VIB71_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEQ8822843.1"
                     /translation="MNIEEAKELVDNSKFYGKTSSVIKAEVRDIIDQLNQPKPEVPQC
                     VADWIEECKEEDLTLKGLFSNSDMPAKIFDWIFGSDENCRLMAEAWINGYTVEKEKLY
                     TVDLPNGQPLVRGINTLYFSQNLATENVKLTESEIRKDFEWAWQFAEEVTE"
     gene            complement(720..965)
                     /locus_tag="VIB71_001109"
     CDS             complement(720..965)
                     /locus_tag="VIB71_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822844.1"
                     /translation="MIPNFRGFNKKTKKMYSIDGFKSSERKIYRCSLADDEFRSGRLE
                     TFHFVEDNLVEKCNRPPERFYRQKQVRKSDRRLMARQ"
     gene            complement(962..1156)
                     /locus_tag="VIB71_001110"
     CDS             complement(962..1156)
                     /locus_tag="VIB71_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822845.1"
                     /translation="MTTTKKHVVRVYNKGITATYAIYDKKLFKEHEFATKNEAMRFIR
                     QLELANDKRATEYYLREVEK"
     gene            complement(1143..1655)
                     /locus_tag="VIB71_001111"
     CDS             complement(1143..1655)
                     /locus_tag="VIB71_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822846.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSKSYFERGRY
                     MASQLGLIQSRALKKYDCYFSTIAVEKNSVMEPNQQSMLKIGIVTGIILGRLIADNVA
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKEKALEYCGKTVKDDEADAILIGSYYVNQGY
                     LDELETHDYY"
     gene            complement(1652..1990)
                     /locus_tag="VIB71_001112"
     CDS             complement(1652..1990)
                     /locus_tag="VIB71_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822847.1"
                     /translation="MEQIKITETGMVVISDKALKTFVIAGHLSERWEFTSKFKKLDEP
                     SLDENGDLFEPVYELMLEARSKGQISITSSYCGKNHKKDTDEIIKVFSFIEDNKRNIF
                     ENLGIRGVLE"
     gene            complement(2186..3214)
                     /locus_tag="VIB71_001113"
     CDS             complement(2186..3214)
                     /locus_tag="VIB71_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEQ8822848.1"
                     /translation="MQELQLKVTQAQVEIIDREKFEQNINEVVAKYQNYAVTAGTIKD
                     DKQVLADLRKLKKQLSDERIKVKKELSKPADDIDGYIKQASKPLDDTIDKIATDVKEF
                     EDHQKALRLDTVKSYLSNKASEYMLDPRIFDEKAMEYTKAGNFMADGVTLKKVTMKSL
                     EDLVTFEYQKEQEVEKAKATVSGQCAEYGMTDQPYIRMLKEMTLVEVLGQIKADYLAE
                     KQKQEMRKAEEEREQLLAAQQTKEQEQAQKSAEIPQIDKETGEILDGWQLSQNNQETL
                     TGAENEFKKYNQKMTLEVYFEDTAEKDRFKTGLTQLGFDFKKNYQVSGYQNIEPLTQA
                     ELARRCGW"
     gene            complement(3224..4015)
                     /gene="bet"
                     /locus_tag="VIB71_001114"
     CDS             complement(3224..4015)
                     /gene="bet"
                     /locus_tag="VIB71_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEQ8822849.1"
                     /translation="MANQLSTQQVKRDITTDPTLLTGADIKKYFDPQNLLSEKQVGQA
                     LALCKGRNLNPFANEVYIVAYKNNSGTDFSLIVSKEAFMKRAERCEGYDGFEAGITVM
                     RNGEMVEIEGSLKLPDDVLIGGWAIVYRKDRSHRYKVTVDFNEYVKLDKYGNPRSTWK
                     SMPGTMIRKTALVQTLREAFPDELGNMYTDIDGGDTFDAIKDVTPQETQEEVRARKMA
                     QIEQYKQEQTQKQTQKADTSYPVDEVSEHTDDPVQGELLDGELEY"
     gene            complement(4018..4347)
                     /locus_tag="VIB71_001115"
     CDS             complement(4018..4347)
                     /locus_tag="VIB71_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822850.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNKKDVLAYNVELTDSIQLASF
                     LPEEAYNIQKEKIDNLAETLGCDVVVIEASYDLKFIDGEDVPELTKEQKVKSMVNGMF
                     EQVFGGE"
     gene            complement(4403..4609)
                     /locus_tag="VIB71_001116"
     CDS             complement(4403..4609)
                     /locus_tag="VIB71_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822851.1"
                     /translation="MTPEQAEKAKIRAKQELETFSIYLDQAVDELGGVLTSREVFLAA
                     GFTYLGAGQTDIHAAVEGLCEQIQ"
     gene            complement(4618..4758)
                     /locus_tag="VIB71_001117"
     CDS             complement(4618..4758)
                     /locus_tag="VIB71_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822852.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKARYVTLLRQLRKKY
                     AI"
     gene            complement(4755..4988)
                     /locus_tag="VIB71_001118"
     CDS             complement(4755..4988)
                     /locus_tag="VIB71_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822853.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKNGVKP
                     IFNWINLYAFGTDITTAEADRLRIERYKQENVL"
     gene            complement(4969..5355)
                     /locus_tag="VIB71_001119"
     CDS             complement(4969..5355)
                     /locus_tag="VIB71_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ8822854.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHEDNMPIEVVNLAL
                     REAVENNKISWKYINKILVDWYKSGDTTVEKVRDRLQRFDDSKKQRSVTTSNVPSWSN
                     PDYKEPDLEEFALGSMDGIEDGSGDF"
     gene            complement(5838..6023)
                     /locus_tag="VIB71_001120"
     CDS             complement(5838..6023)
                     /locus_tag="VIB71_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822855.1"
                     /translation="MNKLELFLLVTTIILAIITRVQHEVIKKHNSPENKRRIFREVAL
                     ENSKGWSEKRSGGKVVS"
     gene            complement(6025..6336)
                     /locus_tag="VIB71_001121"
     CDS             complement(6025..6336)
                     /locus_tag="VIB71_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEQ8822856.1"
                     /translation="MPKAEITYRAVDVNETASHGDYKHLIQQWEGLTVATAKQWATEM
                     RDHPDFKQFVLNPTHRIVFIDYEGFKLFVQWKSRNRYKTKKETLSEMLENIKFEKRVG
                     A"
     gene            6479..6715
                     /locus_tag="VIB71_001122"
     CDS             6479..6715
                     /locus_tag="VIB71_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822857.1"
                     /translation="MIFFFLSVVSKHINQNFNVDNQLVEFVVAELNQMNAPITQKQAQ
                     HIVNILEYVSKSTSKSTIAAMTNALLELGVLKGD"
     gene            6857..7663
                     /locus_tag="VIB71_001123"
     CDS             6857..7663
                     /locus_tag="VIB71_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HEQ8822858.1"
                     /translation="MLNIDTQFVDTIGKILSDYVSHSEITRMGEVLGYPQNDQNSGFN
                     KHKRVHNLVSDILNRTQNTDNIKLVIEYVCNPLRYINEVSIFEQLRTAINIPLSLKGL
                     IVSDSGQIVTTTTSKTLSEAKKRFETLDSRLKELKVHPHVLKFCTQELLQENYFHAVF
                     EASKGVFHRIRLLTGSAMDSASLIDQCFKPGEPIVIINGNKLQTLDEQSEYKGLKNLL
                     LAIAHLYRNSKAHKLKYYNPDNLNDALTALTLMSLAHNLLDSCSNTRRLD"
     gene            complement(7598..7864)
                     /locus_tag="VIB71_001124"
     CDS             complement(7598..7864)
                     /locus_tag="VIB71_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822859.1"
                     /translation="MEEKKFFTTYEMDLMNSVVTLQKSILTQTEHLSDQLTKKLHHLE
                     DYNSPIDDEAIRLAEVTAEFYKLLIKSPSVGATVKEIVSEGHKR"
     gene            complement(7896..8621)
                     /locus_tag="VIB71_001125"
     CDS             complement(7896..8621)
                     /locus_tag="VIB71_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEQ8822860.1"
                     /translation="MNHLINVTLNENQEPVVSARDLHKELKVKTRFSEWVKQNFKILE
                     EGYDFTSVVGTTVVNNGAVREIQDYVLSLDAAKNLAMVSKTDKGKEVRKYFIQVEKDF
                     NSPEKIMARALLMADKKVHKLESQIEADRPKVLFADAVSASHTSILVGELAKLLKQNG
                     VNIGATRLFTWLRKHGYLIKRNGRDWNMPTQKSVELGLIRVKETSITHSDGHITVSKT
                     PLVTGKGQQYFINKFLNQEYLPV"
     gene            complement(8672..8899)
                     /locus_tag="VIB71_001126"
     CDS             complement(8672..8899)
                     /locus_tag="VIB71_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEQ8822861.1"
                     /translation="MTKKQRLKQEHLKPKKRLREERLKREYTEMYMADLIGLKNRKGY
                     SEKEDGLQPFKDYEMAIISQKFNVSESELFF"
     gene            9059..9814
                     /locus_tag="VIB71_001127"
     CDS             9059..9814
                     /locus_tag="VIB71_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8822862.1"
                     /translation="MNILGNSIKEIRKSKKMTQKELAKLTGFKQNTISNHENGNRQLD
                     EVDIRKYAKALKIEPQQLFDYSSSPTNPQVELIPSTLQKITSTSSQLEHKRQLNVLDY
                     AETQLEQQNTVESNKDIVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIELPVDYD
                     ADFVIPVHGDSMEPKYHSGDYVFVKLSVELADGDIGVFEYYGDAYIKQLLINDEGAFL
                     HSLNSKYEDIPVDRDSDFRIIGEVVGSYSGNHS"
     gene            9852..10532
                     /locus_tag="VIB71_001128"
     CDS             9852..10532
                     /locus_tag="VIB71_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822863.1"
                     /translation="MKFWNLVVKTLKQKNNQAVAEKVVKITESTTNIKSPSYPDLNKY
                     RVNPSGKRYDDTYITGVGYKLREILLLVWWGRTKNPRKPTSKPPRYFFYDYHLNTKKT
                     TDMFIRDGLLKKNKEGCITLTLSGKVLYDEYKILWEIHSYKGYIGELPNMDRVFHGWN
                     YNSYKANNNLLEIRHLEDIVKYNTIMRDQYKKGSNEYNAFQQDIEQDKNQIALLFNEH
                     QLLENIDN"
     gene            10668..11807
                     /locus_tag="VIB71_001129"
     CDS             10668..11807
                     /locus_tag="VIB71_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8822864.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAK
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSIRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(11901..12941)
                     /gene="rfbB"
                     /locus_tag="VIB71_001130"
     CDS             complement(11901..12941)
                     /gene="rfbB"
                     /locus_tag="VIB71_001130"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEQ8822865.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGE
                     GKNVRDWIHTNDHSIGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(13185..13778)
                     /locus_tag="VIB71_001131"
     CDS             complement(13185..13778)
                     /locus_tag="VIB71_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEQ8822866.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(13778..14647)
                     /gene="rfbA"
                     /locus_tag="VIB71_001132"
     CDS             complement(13778..14647)
                     /gene="rfbA"
                     /locus_tag="VIB71_001132"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEQ8822867.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTSQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHELAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(14705..15811)
                     /locus_tag="VIB71_001133"
     CDS             complement(14705..15811)
                     /locus_tag="VIB71_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEQ8822868.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGNDFKGLIGFDNCLYASGAARVEGATLCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDNYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVPGLKNFYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSNGKA"
     gene            complement(15846..16634)
                     /locus_tag="VIB71_001134"
     CDS             complement(15846..16634)
                     /locus_tag="VIB71_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEQ8822869.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(16624..17310)
                     /locus_tag="VIB71_001135"
     CDS             complement(16624..17310)
                     /locus_tag="VIB71_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEQ8822870.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(17382..18038)
                     /gene="nth"
                     /locus_tag="VIB71_001136"
     CDS             complement(17382..18038)
                     /gene="nth"
                     /locus_tag="VIB71_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEQ8822871.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(18035..18718)
                     /locus_tag="VIB71_001137"
     CDS             complement(18035..18718)
                     /locus_tag="VIB71_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ8822872.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(18799..19317)
                     /locus_tag="VIB71_001138"
     CDS             complement(18799..19317)
                     /locus_tag="VIB71_001138"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEQ8822873.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(19468..21678)
                     /gene="recJ"
                     /locus_tag="VIB71_001139"
     CDS             complement(19468..21678)
                     /gene="recJ"
                     /locus_tag="VIB71_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEQ8822874.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(21675..22439)
                     /locus_tag="VIB71_001140"
     CDS             complement(21675..22439)
                     /locus_tag="VIB71_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ8822875.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGTFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(22439..23368)
                     /locus_tag="VIB71_001141"
     CDS             complement(22439..23368)
                     /locus_tag="VIB71_001141"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEQ8822876.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(23383..24018)
                     /locus_tag="VIB71_001142"
     CDS             complement(23383..24018)
                     /locus_tag="VIB71_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEQ8822877.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(24011..25249)
                     /gene="hflX"
                     /locus_tag="VIB71_001143"
     CDS             complement(24011..25249)
                     /gene="hflX"
                     /locus_tag="VIB71_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEQ8822878.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRERRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(25322..26221)
                     /gene="miaA"
                     /locus_tag="VIB71_001144"
     CDS             complement(25322..26221)
                     /gene="miaA"
                     /locus_tag="VIB71_001144"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEQ8822879.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            26355..26531
                     /locus_tag="VIB71_001145"
     CDS             26355..26531
                     /locus_tag="VIB71_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEQ8822880.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(26649..27557)
                     /locus_tag="VIB71_001146"
     CDS             complement(26649..27557)
                     /locus_tag="VIB71_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEQ8822881.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFSYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGVLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LPLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
BASE COUNT         8115 a         5902 c         4802 g         8836 t
ORIGIN      
        1 ccacagagcc atcgcaggct cttgagcgct tgcgtggggt tataattttg tcagcgatac
       61 ccatttaaac tgtggaaact gttctgcttg tttgcgggtg catttagtag cctgatgtgg
      121 attatcaaca taagatatat acctgcaagt tttatataaa taatacttat gccatttttc
      181 gctatataac actcctaact cttcagtcat tcagtcacct cttcagcaaa ctgccacgcc
      241 cattcaaaat ctttgcggat ttcggattcg gtgagtttta cattttcggt tgctagattt
      301 tgactaaaat acaaagtgtt tatgccgcgc actaaaggtt gaccgtttgg taagtcgaca
      361 gtgtagagct tttctttttc tactgtgtag ccgttaatcc atgcttcagc cattaaccta
      421 caattttcgt cactaccaaa aatccaatca aaaatttttg caggcatatc gctgttagaa
      481 aacaagcctt ttaaagttaa atcttcttct ttgcactctt ctatccaatc cgccacacac
      541 tgcggtactt ctggttttgg ttggtttaac tggtctataa tgtcgcgaac ctcggctttt
      601 ataacactgc tagtctttcc ataaaatttt gaattatcta ctaattcttt cgcttcttct
      661 atattcattt ttgcatctcc tctaatactt ttaaaaaaca ctgctcagca atgacttgat
      721 cactgccttg ccataagtcg cctgtcactt ttgcgtactt gtttttgtcg ataaaatcgt
      781 tcaggtggtc tgttgcactt ttccacaaga ttatcctcta caaaatggaa tgtctctaag
      841 cgaccagagc gaaactcatc atctgctaag ctgcatctgt atattttgcg ttcacttgat
      901 ttaaagccat caatgctata cattttttta gtttttttgt taaaccctct aaaatttggt
      961 atcatttctc tacctctctc aaataatatt ctgtcgctcg cttatcatta gctaactcta
     1021 gctgtctaat aaaccgcatc gcttcgtttt tggttgcgaa ctcgtgctcc ttaaacagct
     1081 ttttgtcata gatcgcgtaa gtcgctgtaa tacctttgtt gtaaactctc acaacgtgtt
     1141 ttttagtagt agtcatgtgt ctccaattca tcaagatagc cttgattgac atagtatgag
     1201 ccaatcaaaa tagcatccgc ttcatcatct tttactgttt ttccgcaata ttcgagagct
     1261 ttttctttcg attgtgcttt catcgctttt ttagagcggt ctttgtagct aaacttccag
     1321 tgcttacgcc acgttgatac atttataaag gcgacgttat cagctattaa tcttcctaag
     1381 ataattcctg taacaatacc gattttaagc atggattgct ggttaggttc cataactgaa
     1441 tttttttcga ctgcgattgt actaaaatag caatcgtatt tttttaatgc tcgtgactgg
     1501 attagtccta attggctagc catatagcgt ccgcgctcaa agtaggattt actcttatgt
     1561 tttaagacac cactctggat aaggtctgag cctttaaata aggcccaccc tgttccagat
     1621 gttgagatgt ctaacgataa aactagattg ctcattcaag caccccacga ataccaaggt
     1681 tttcaaaaat atttctcttg ttatcttcga taaacgagaa tacttttatg atttcgtctg
     1741 tgtctttttt gtgatttttg ccacaatatg atgatgttat gctaatttgt cccttcgacc
     1801 tggcttcaag catcaactcg tatacaggct caaacaaatc tccgttttca tcaagtgatg
     1861 gctcatctaa ttttttaaat ttagaggtaa attcccacct ctccgataaa tgtcctgcaa
     1921 tcacaaaagt tttgagtgct ttatcgctta taacgaccat tcctgtttct gtaattttga
     1981 tttgttccat atttctcacc ttttaaaatc cacactcgcc ctaaaattgt gtgtgagcat
     2041 tggcaaggac gagtgtagca attttttata tcatcaatcc tgttaacttg acgatattcc
     2101 aactttcctt tctcactcgg aaaatattga tactgcaaag gctgagcttc actttgcaat
     2161 aggttgttaa aaaactattt tttatttacc atccgcaccg ccgagccaat tcagcttgag
     2221 taagaggctc tatattttga taaccgctga cttgataatt ttttttaaaa tcaaaaccta
     2281 gctgagttag accggtcttg aaacggtctt tttcagccgt atcttcaaag tacacctcaa
     2341 gtgtcatttt ttgattgtac tttttaaact cgttttcagc tcctgtgagc gtttcttggt
     2401 tgttttggga taattgccaa ccatccaaga tttcgcctgt ttccttgtcg atttgtggta
     2461 tttctgctga tttctgagcc tgttcttgtt ctttagtttg ctgagctgct aaaagttgct
     2521 ctctttcctc ctcggctttt cgcatttcct gcttttgctt ttcagcgaga taatcagctt
     2581 taatctgacc tagcacctct acaagcgtca tctcttttag catacggatg taaggttggt
     2641 cagtcatacc atactcagca cattgtcctg agacggtagc ttttgctttt tcgacctctt
     2701 gctccttttg atattcaaag gtaaccaagt cctcaagaga tttcatggtg acttttttga
     2761 gggttacacc gtccgccata aaattgccag ctttggtgta ctccatagct ttttcgtcaa
     2821 aaatacgggg gtcaagcata tactcggatg ccttattaga caagtagctc tttactgtat
     2881 ctaatcgcag cgctttttga tggtcttcga attctttgac atcagttgca atcttgtcaa
     2941 tcgtgtcatc tagtggcttg cttgcctgtt tgatatatcc atcaatgtcg tcagcaggct
     3001 ttgagagttc cttttttact ttgatacgct catcagacaa ctgttttttg agcttgcgta
     3061 gatcagctag gacttgcttg tcatctttga tagttccagc tgtgactgca taattttggt
     3121 attttgccac aacttcgttg atgttttgtt caaatttttc acgatcaata atttcaactt
     3181 gtgcctgtgt gacttttaat tgtaattctt gcatggtttc ctcctaatac tccagttctc
     3241 catcaagtag ttctccttgt actggatcat cagtatgttc agacacttca tcaacgggat
     3301 agctagtgtc tgctttttga gtttgtttct gagtctgttc ttgcttgtac tgctcaatct
     3361 gtgccatctt ccgtgctctg acttcttcct gtgtttcctg aggagtcaca tctttaatag
     3421 catcaaaagt atcgccaccg tcaatatcgg tgtacatatt accgagttca tcaggaaaag
     3481 cctctctaag tgtctgaaca agtgctgttt ttctaatcat tgttcctggc attgatttcc
     3541 aagtacttcg tggattacca tatttgtcaa gtttgacata ttcgttaaag tcaacagtaa
     3601 ctttgtatcg atgtgagcgg tctttgcggt aaacaatggc ccatccacct atcaaaacat
     3661 catcaggtag ttttagagag ccctcaattt caaccatctc accatttctc ataacagtaa
     3721 tgccagcctc gaatccatca tatccttcac aacgttcagc acgtttcata aatgcctctt
     3781 tagatacaat caaactgaaa tctgtgccgc tattattttt ataggccaca atataaactt
     3841 cgtttgcaaa tggattaagg ttgcgcccct tacacaaagc cagagcttgc cctacttgtt
     3901 tttcgctaag caagttctga ggatcaaaat attttttaat atcagctcct gtcagcaaag
     3961 ttggatcagt tgtgatatca cgtttaactt gttgtgttga taattgattt gccatctcta
     4021 ttcacctcca aaaacctgct caaacattcc gtttaccata cttttaactt tttgctcttt
     4081 tgttaactct ggaacatcct cgccatcaat aaattttagg tcatatgacg cttcgataac
     4141 tacaacatca cacccaagcg tttctgccaa attatcaatt ttttcttttt gtatgttgta
     4201 agcttcttct ggtaaaaatg atgccagttg aatgctatct gtaagttcca cattataagc
     4261 aagtacatct tttttgtttt tgaaactctt taaaaaactt ccgtcttcag tgtttcttag
     4321 cactacaatt ttttctttga tgttcatttc atttcctctt tttgtgtttt agttgctctc
     4381 ccagtcttca ctaaatttaa aatcattgga tttgctcaca taatccctcg actgcagcat
     4441 gtatatctgt ctgacctgcg ccaaggtagg tgaatcccgc tgccaaaaag acttctcgcg
     4501 aagttaaaac tccaccgagt tcatcaactg cctggtcaag gtatatgcta aacgtttcaa
     4561 gttcttgttt agctctgatt tttgcttttt ctgcttgttc tggtgtcata tttcctccta
     4621 aatcgcatat ttcttacgca attgccgcaa tagtgtcacg taccgtgctt tatcaactag
     4681 tccaaaatca agcaatctct cacgctcttg atgacttgct cggtaccaga taagcgtttc
     4741 tctatgctgt tttgtcataa cacattctcc tgtttatatc gctctatcct taatcggtct
     4801 gcttctgctg ttgttatatc agttccaaaa gcgtataggt ttatccaatt aaaaattggc
     4861 ttaactccat ttttttcgat tccttcagcg cagtaactag caaacttagc aaaagtctct
     4921 ttactcgccg ttttaccaaa atcttttttg atttgtttgt taaaaaaatt aaaaatctcc
     4981 tgatccatct tctataccgt ccatgcttcc tagagcaaat tcttctaaat ctggttcttt
     5041 gtagtctgga ttcgaccagc ttgggacgtt tgaggtagtt acacttcgtt gttttttact
     5101 atcgtcaaac cgttgcaacc tgtctctgac cttttctact gtcgtatctc cagatttata
     5161 ccaatcaact aagattttat tgatatactt ccaactgatt ttgttgtttt ctaccgcttc
     5221 tcttaaggca aggttgacaa cttcaattgg catgttatct tcgtgaatcc acttttgaat
     5281 atcttcgatt tcaaatggcg atatcatccg tccaaaagtt aattggaaat tttcaaaaag
     5341 ctttttttcg tccatagctc ctcctgatgt tgatgatgat gcttattatc tgttagtatt
     5401 tattgttatt tagtatttat ttataagtta gtaattatta gtgttacgtt ttacaacttt
     5461 gtaaaataca actttgtaaa atacaacttt gtaaaacgtt aagttgtaaa atcactaatc
     5521 atttttttaa atgcttgttc ggatatcttt ttatctgagc aaaatctata atattgtatg
     5581 cctttccctc gccctaaaga ttttctgtaa gttctcacat atccgactct ctctaattct
     5641 tctaagcaag tccttacaac tctcacgcta tctctggacc ttctagccaa ttcctctgga
     5701 tatactctcc aatcttcttt atttctaaga attaccataa gcaggccttt tgattttagg
     5761 gataattcac aatcatctat aaattcgttg ctaacggatg tatagctact tgtcgtattt
     5821 ttgaaaaatg tactgcatca gctgaccacc tttcctccag aacgcttctc gctccaccct
     5881 ttgctgtttt ctaaagccac ttctctaaaa attctgcgtt tattctctgg cgaattatgt
     5941 tttttaatga cttcgtgttg tactctagtg atgattgcta agatgatcgt tgttactaat
     6001 aaaaatagtt ctaatttgtt catgttatgc tcctactctt ttttcgaatt taatattttc
     6061 aagcatttct gacagtgtct ctttttttgt tttataacga ttgcgagatt tccactgtac
     6121 aaacagtttg aatccttcgt aatcaatgaa tacgattcta tgcgttggat ttaatacaaa
     6181 ctgtttaaag tctggatgat cacgcatttc tgtcgcccac tgctttgcag tagcaactgt
     6241 caacccctcc cattgttgaa tcaagtgttt ataatcacca tgagaagctg tttcattaac
     6301 atcaactgct ctataagtaa tttctgcttt tggcatatta atatcctctc tcttgtggta
     6361 taattaagta aattaatcta gttttgagtc cgattgccgt cggacttttt ttgttatctg
     6421 aattcgtcca agctgacacc taagacatcg gcgattttaa cgacatcatc aaatttcaat
     6481 gatttttttc ttcctttctg ttgtctcaaa acatatcaac caaaatttca atgttgacaa
     6541 ccaattagtt gaatttgtcg ttgcggaact taatcaaatg aatgcaccta ttacacaaaa
     6601 gcaagctcag catatcgtta atattttgga gtatgtctct aagtcaacct ctaaatctac
     6661 tatcgcagct atgacaaatg cattgttaga gcttggcgta cttaagggag attgatgcaa
     6721 tcaactttac cggtttttat cagttcaggg tctatcttat gataggctct ctttttctct
     6781 ccgctatacg gatatcgttt tggtctcatg tggttctcct ttctgtggta taatttaaat
     6841 aaaaacgagg tttgttatgt taaatattga cacccaattc gttgatacaa tcggtaaaat
     6901 actatctgac tatgtttcgc attctgaaat aacccgaatg ggcgaagttt taggttatcc
     6961 ccaaaacgac caaaattctg gatttaacaa gcacaaacgg gtgcacaatc tcgtgtccga
     7021 tatattaaat aggacacaga atacagataa tataaaactt gtgattgaat acgtctgtaa
     7081 tcctttaaga tacattaatg aagtttcaat ttttgaacag ttaagaaccg ccattaacat
     7141 tccgctctcg ctaaaaggtt tgattgtatc agatagcgga caaattgtta ctactactac
     7201 ttcaaaaact ttatcagagg ccaaaaaacg cttcgaaaca cttgatagta gattaaaaga
     7261 attaaaagta caccctcacg ttttaaaatt ctgcactcaa gagctcttac aagaaaacta
     7321 ttttcatgcc gtatttgaag caagtaaagg tgtttttcat cgtattcgtc tgctaacggg
     7381 ctcagcaatg gactcagcta gtctgataga tcaatgtttc aaacccggag aacccattgt
     7441 gattatcaac ggtaataaat tgcagactct agacgaacaa agtgagtata agggattaaa
     7501 aaatttgcta cttgcaatcg ctcaccttta tcgcaactct aaagctcaca aactcaaata
     7561 ctacaatcca gataatctca atgacgctct tacggcctta acgcttatgt ccctcgctca
     7621 caatctcctt gacagttgct ccaacactag gagacttgat taacaacttg taaaattctg
     7681 ctgttacctc agccaatcta attgcttcat catcaatcgg actattgtag tcttctaggt
     7741 gatgaagctt ttttgttagt tgatctgaca aatgttccgt ttgcgttaag attgattttt
     7801 gaagagttac aactgaattc atcagatcca tttcatatgt agtaaaaaat tttttctctt
     7861 ccatattttc tcccttcgtt agttttgtta cgtttctaaa ctggtagata ttcctgatta
     7921 agaaatttgt tgataaagta ttgctgacct tttccggtta ccagaggtgt cttgcttact
     7981 gtaatatggc catcagaatg ggtgatacta gtttccttga ctctgataag tccaagctct
     8041 acgcttttct gagtaggcat attccaatcg cggccattgc gcttgataag atagccgtgt
     8101 ttacgaagcc aagtgaagag acgggttgct ccaatattta ccccattctg cttgagtaac
     8161 tttgcaagtt ctccgactaa gatagaggta tggctagcac ttacggcatc agcaaatagt
     8221 actttgggac ggtccgcctc aatctgagac tctaatttat gcactttctt gtccgccatc
     8281 agcaacgccc ttgccatgat tttctcagga ctgttgaagt ctttttcaac ctggatgaag
     8341 tatttacgga cttctttgcc tttgtcagtc ttggatacca ttgccaaatt tttggcagca
     8401 tcaagtgaga gaacgtagtc ttggatttct ctgacagccc cattatttac aaccgtagtt
     8461 ccaactacac ttgtaaaatc atatccttct tcaagaattt taaagttttg ttttacccac
     8521 tcactaaaac gagttttgac ttttaattct ttatgtaagt ctcttgcact tactactggt
     8581 tcttgatttt cgtttagtgt tacgttaatt agatgattca tattgtcctt tctagtgttg
     8641 tacgctttat ctcgttttga gatatttttg tttaaaaaaa taattcactc tctgaaacat
     8701 taaatttttg agaaatgata gccatttcat aatctttaaa aggctgtaaa ccatcttctt
     8761 tctcagagta accttttcta ttttttaaac caattaaatc agccatatac atttctgtgt
     8821 actcacgttt taaacgttct tctcttaaac gctttttagg tttgagatgt tcctgtttta
     8881 aacgttgttt tttcgtcatt cccccacctc ctttcgcttt gcttaattcc ttaagcttga
     8941 ttatattata tctcaaaacg agatattttg tcaactattt tttatctctt tttgagattt
     9001 ttttatttac ttttttgttt cttgatgtta tatttatagt agagaaagga aaaatattat
     9061 gaacattctc ggaaattcta tcaaagaaat tcgaaaatcc aaaaaaatga cccaaaaaga
     9121 gttagcaaaa ctaactggat ttaaacaaaa tacaatttct aatcacgaaa atggtaatag
     9181 acaacttgac gaagtagata ttcgaaaata tgctaaagca ctgaaaatag agccacaaca
     9241 gctttttgac tattcctctt ctcccacaaa cccccaagtt gaactcatcc catctactct
     9301 acaaaaaatc acttctactt cttctcaatt agaacacaag cgacaactaa acgttcttga
     9361 ttatgccgaa acacaattag aacaacaaaa cacagtagaa agcaataagg atatagtaga
     9421 agaaccacaa gccacctact acacctacaa ttactacgac cacgcagctt cagctggtac
     9481 aggtcagtat ctaaatgatg tacaagtaga aacaattgaa ttaccagtcg attatgacgc
     9541 tgattttgtc ataccggttc atggcgattc tatggaacca aagtatcact ctggggacta
     9601 tgtgttcgtt aagctatccg tagagctcgc agatggcgat ataggcgtct ttgaatacta
     9661 tggtgacgct tatatcaaac agctacttat aaatgacgag ggggcatttc tgcacagttt
     9721 aaatagcaag tatgaagata tacccgtaga tagagatagc gactttagaa ttattggtga
     9781 agtcgttgga agttattcgg gaaatcatag ctgatgagtg atagttaaag aatttaggtt
     9841 aggagattga tatgaagttt tggaatttgg tagttaaaac tctaaaacag aaaaataatc
     9901 aggctgtagc tgaaaaggtt gtaaaaatta ccgaatcgac tactaatata aagtcaccaa
     9961 gctatcccga cttaaataag tatagagtaa atccaagcgg gaaaagatat gatgatacat
    10021 acataacagg tgtaggatac aaactacgtg agattttatt gttggtgtgg tgggggcgta
    10081 ctaaaaaccc cagaaaaccg acaagtaaac caccacgcta cttcttctac gattatcatt
    10141 taaatactaa aaaaactaca gatatgttta ttcgagatgg attgcttaaa aagaataaag
    10201 aagggtgtat tactttaaca ctatcgggga aagttcttta cgatgagtac aaaatcctct
    10261 gggaaataca ttcgtataaa ggatatatcg gtgaattacc aaacatggat agagtgttcc
    10321 acggatggaa ttacaactct tataaggcca ataacaattt attagagatt agacatttag
    10381 aagacattgt aaaatacaat acaattatga gagatcaata taaaaaaggt agcaatgaat
    10441 ataatgcgtt tcaacaagat attgagcaag ataaaaacca gatagcacta ttgttcaacg
    10501 aacatcaatt gcttgaaaat atcgataatt agttaatcta aaacaaaaaa ccccacgctc
    10561 tcaaagtttg gcgactctga gcgtgaggca agacagtata gtaaaaacct gcttcgcagt
    10621 aggtctcttt actataccta ttttaacaga aaatgaggta aaaaacaatg tggtcagaaa
    10681 aacacaaaag cggaaaagta aattttgtag aacggtacaa acacccgtat actggcaagt
    10741 ggtgcagagc ttctgtcctt atggaaaaag acacgccacg aatacgaaaa gaagccaaaa
    10801 aatatcttga cgaaaaaata tctaaaatct taacaagtct taccacaacc gatgcctacc
    10861 tactagatgt catgaacgaa tggtgggaac atcatcagaa atcactcaaa tcaacttcta
    10921 tccgctctct tgattttaga ataagagaat tgcgaaactt aattgatcca gaagtgatga
    10981 ttgccaagat aaccacgaaa tacctgcaaa gtattatcga caaaatacca ggtagttatg
    11041 acaaacgtaa acgagcacgg cagctgctta aacaaacctt cgactacgct atcgctttag
    11101 aatatgtctc aatcaatccg gttattagta cccaactcgc aaaacctgtt aagaccatca
    11161 aagactttga agacgttgcc cagaagtttt tagaaaaaga tgaactcaaa aggctattag
    11221 atgaaatgta tagacgtaaa ggatcgatta aaatggctta tctggcagaa tttatgagct
    11281 taaacggctg ccgcattgga gaagctctag ctatacagcc agacaatatc aaaaatgata
    11341 tcattgaaat ccacggaact cttgactaca cctcaaatgg ctatagaaac gctatcaaaa
    11401 ccacccctaa aacaaattcc agttggcgtg aaacattgat aaccaaacgt gaaaaagaaa
    11461 ttattcagga tatactgaaa attaatgctc ttgaaaaaaa tactaatcct aattacaagg
    11521 acatgggcta catcttcatt tccagaaatg gcgttcctat tcaagacaac gccctcaaca
    11581 cctctatcag agcggcaaat aagagactag aaaaaccgat tcaaaaagaa ctcaccagcc
    11641 acatctttcg tcataccctg gtgagtcgcc ttgcagaaaa caaagtgccc ttaaaaacta
    11701 tcatggatag agttggacat gctgactcga aaactactca acaaatctat acccacgtca
    11761 cgaaaagcat gaaaaatgaa gtcgtcgaca tcttaaaccg gctataatat accccaaata
    11821 tgccccaaaa atgccccaaa acacaagaaa aaaccttgat atcttcaaca aacgttgata
    11881 tgacaaggtt ctttaatgtt ttatttaatc acttcttgag ttttagcata cttggcttct
    11941 acagcatctt tttctgcttt ccaccatgtc tcattttctg tataccactt aatagtttct
    12001 tccaaacctt ctgaaaagtt tgtaaattgt ggttcccagc cgagttcttc acgcaatttt
    12061 gtagaatcaa tagcgtaacg aagatcgtga ccagcacggt cagttacgtg atcataagcg
    12121 tcttttggtt gacccatttt ctcaaggata agctcaagaa cttccttgtt gtttttctcg
    12181 ccgtcggcac caataaggta tgtttcaccg atacgaccct tagtcaaaat agcccatact
    12241 cctatagaat gatcattagt atgaatccag tcacggacat ttttcccttc accgtatagt
    12301 tttggcttga tgcctgataa aatattggtg atttggcgag gaataaattt ctcaatgtgc
    12361 tggtaaggtc cgtagttatt ggaacaattt gaaatggtcg ctttcacacc gaaggaacgt
    12421 acccatgcct taacgataag gtcagaagct gccttagttg atgagtaagg tgatgatgga
    12481 ttgtattttg tttcagcagt gaatttttca cctggtcctt caccctgtcc tggaaggtct
    12541 tcacgaagtg gaagatctcc ataaacttca tcagttgaca cgtggtggaa acggatatcg
    12601 tatttacgag ctgcttcaag caaagtgtaa gttccgataa agtttgtatg gataaatgga
    12661 cttggatctt ccaatgagtt atcgttgtga ctctcagccg catagtgaac aatagcatcc
    12721 gttttggcag ccaatttgtc taccaattca gcgtcagcga tatcaccaac aactaactca
    12781 acacgatcac caagaatagc ttcaatgtta gcacggttac ctgcatatgt caatttatca
    12841 aggacagtta catgaacatc tgggtggtta ttgtagacat agtgcacaaa gttagatccg
    12901 atgaaaccag ctccaccagt tacgataata tttttataca taagatataa agggaccttt
    12961 cgtttccgaa aaaatctatt aaaagtaata actctaacaa agacgtttta ggcctaagaa
    13021 aacatcgctt tctaagattt gagtcccatg ttcagctcaa agagagaaac tgaactttcc
    13081 tttcatcatt tttagttgtt acttgttacc tgaagtagag aagaataact cccctcatat
    13141 ccacctcaaa tgattaatcc caatcatctg agtatgttgt ttccctatag gtcttttggt
    13201 ttcagtggtt tgacatcact aagaagagga tggtttttat ctgcttcaga aacttctgca
    13261 gctgctagat tttcccaagt aatcccaaga cttgggtcag catagtttac aaaagcatac
    13321 ttaggtttca agtcaagagc ccagtagtca ttgacaagat aactgtaaga gacagtctct
    13381 gaaagaactt gaaagccatt agcaacccct ctaggaacaa acattccttt tgaagcatca
    13441 atcactgtct ggtagacgtt tccaaaagtc tctccctcac gaagatcaac ccaagctcct
    13501 aaaaccttgc catcatcagc aactgagatg tatttatccc aaggttcagc atgaagtcca
    13561 cgcagcacat gctgacgtga aaaagaaacg ttgttttgta gttttccttc ctcaaaaaaa
    13621 cgttctggaa agccaattgg caacattttt tctttttgga aattttcttt aaaccagcca
    13681 cgattatccc cacgaacagg aatatcaaac tctagtaagc ctgggatttc tttgatttct
    13741 cggcaagcca atggtttgtc aaaaaaagtt tctgtcatta agcttctcca atcaaacgaa
    13801 gcaagtattg cccgtattcg tttttcttta aagactgcgc caattcatgg acatcttctt
    13861 tactgatgta acccatgcga taggcaattt cttccagatt tgccacttga gcgttttgca
    13921 aacgttgaac tgtttcaata tattgagccg cttcaagtag actttcatgc gttccagtgt
    13981 ctagccatgc aaaaccacgc cccatcaatt caacggagag gtcaccacgt tccaagtaag
    14041 ccttgttgac gtctgtaatt tccaactcac cacgcgcgct tggtttaatg tttttagcaa
    14101 tttctaccac gtcattgtca tagaaataaa gtccagtcac tgcaaagtgg gacttaggca
    14161 cttctggttt ttcttcgata gagatagcat tcatgttctc atcaaattcc accactccaa
    14221 agcgctcagg gtctttcact tgataaccaa aaacggtggc tcctttttct ttggcagctg
    14281 ccttttgaag cattttagtg aggccattac cgtggtaaat attatctcct aaaataagag
    14341 caacacggtc atcaccgata aactcctctc caataatgaa agcttgtgct aaaccatctg
    14401 ggcttggttg ttccttatag gataagctaa tgccaaattc tgacccatct cctagcaatt
    14461 cttcgaaacg aggaagatct tgggaagttg aaatgattaa aatatcttta atccctgcca
    14521 acatcaaggt tgacaatggg taataaatca ttggtttgtc ataaatgggc atcaactgtt
    14581 tagatgcggc acgggtcagt ggatacaagc gtgtccctga acctcctgca agaataatac
    14641 ctttcatagt agtgctccta ttcttctata taccctatca ttctatcatt ttttgaaagc
    14701 agtgtcacgc tttaccatta gaccgcaaaa ggtaaggctc aggggaatag tcgctaggcg
    14761 ttaaaagtcc ttcgtgtcct agcaataatt gagctaattc atagccaatc aaaggtccaa
    14821 ctgttaatcc cgatgaccct aaaccactag ctgtataaaa gttcttcaat cctggaacct
    14881 gaccataaaa aggagaataa tcactggtat aagctcttat tcctacacga cacgtttttt
    14941 gagtagcttc ttttaataac ggcaaataag taagagcttg catttcaagt ttttctaaaa
    15001 cctgccaatc aggctccaaa tcatagcctt tatcattttc gtgactcgca ccaacagaaa
    15061 tcttaccttg attgaaagga ataagatcta tttcaccttc tggcataaca actggataat
    15121 tgtcgctgat gatgtgatga acgtcataat ccaagagttg tcccttttgt ggtcgcacat
    15181 caacctgata gcctaaaggc ctcaataagt caggtagcca tgctcctgct gccagaatga
    15241 cctgatcaaa ataatgacca gcaatctcat aaccacttcc ttgctgtttc agagtgactt
    15301 tttggcgaat aactggataa ccactagcct tgagtaacgt ctcacataaa gtagcccctt
    15361 caactctagc agctcctgaa gcgtacagac agttatcaaa gcctatcaat cctttaaaat
    15421 cattccccag ttctttacga tttttaatgg ctaactcacc aataatcggt gattctacct
    15481 ttcttgctaa cgctaattca taaagatctc ttagtttttc ttcctgcttt tttaaaacat
    15541 agatgccatt ttgctgataa aaatctgttg caaaaccatc ttctttgagg tcattgatta
    15601 attgctgata aaagtccgct cctaaacgag ccatgcggta ccaaacttta ttgcgacgct
    15661 ttgaaaacca aggactaata ataccagcag cagccttagt ggcctgtcct tgaccatggt
    15721 caaaaatggt aacttctttt tgaccacttt gttgtaaata ataagcggcg gttgatccta
    15781 caatccccgc cccaataatg gctattttca ttcctggtat ccttttattt taagacctta
    15841 acagcctata aatggctaaa tggattggtc gaggctttgc ttgaaataat gctgacatcc
    15901 caaccgttct cttctttcca cccttggagt ttctccttta atttctccgt aaaaagcacc
    15961 tcaatatgat gccccgggtc aaccgcaaat agtccttctg tcagcatctc ctgtgctgta
    16021 tggtaataga tatcccctgt aatataaacg tctgcgcctt tttgcacagc atcctgataa
    16081 aattcaccac cacttccgcc acagatagca atctttgaaa tcaaagggtt ttccttatca
    16141 taacggataa gtcgcacggt atctaaatca aacacccttt tgaccttact tgctaactct
    16201 tctaacgctt gttctttaac tgttccaata cgaccaatgc caaagccttc tttggtttca
    16261 gacaagtaag ttgcttcctt gatttctagc aggtcacaaa accaatcatt tagcccacct
    16321 ggtacaatgt caatattggt atggctcaca tagacagaaa tgtcatgctt gaccaaatct
    16381 agaaggatat cacgctgagg ggatgaaacc agatctttaa gcggtttaaa gatgggagca
    16441 tgcttagtta taatgagatc aacttcattt ttgatggctt ctgctactgt tgactctcgg
    16501 atatctaaag taatcataac cttacgaatg tctttatcca atgaacccat ttgaagacct
    16561 ttaacgtctc cttccataga taaatcaagt gggcaaaagg cttcataggc atcaattagg
    16621 gttttagctt tcatgaacaa tcacctcttt tatttgttgt atttttgtca agagaagctg
    16681 acgctcttga gttttttctt ctgggatgca ggacaaggca taagctaact tatccatttc
    16741 tcgttgccac ttctctttaa aaacgactga tttttcctga gaaaggtatg gaccaaaacg
    16801 caattctgtc gcggataagg ccttttcacc atgctcagca acgatgattt cataatattt
    16861 gtcattttca gccatgatgg tttctgcaac aattttaaaa gcgttaaccg ataaccaagc
    16921 ccgtaaatca tcctcacgat tgttgggttg taaaaccaga cgttcaatgc cctgcaattt
    16981 ttccttacct gcctctaaaa tatcagcaat caaacggcca cccatgccac aaatggtaat
    17041 ggctgtcaca tcatcagctt cttcaaaggc tgcaaggcca ttggctaagc gcacctgaat
    17101 atgctcggca aggccagact gtgtgacatt tttaagagca gattcgtagg gacccctaac
    17161 cacttcgcca gcaatggctg ctgaaatctg attagtttct accaaaaata tgggaagata
    17221 ggcatgatca ctgccaacat ctaataattt gacacctttt ggaacatagg ccgcaacttg
    17281 ggccaaacgg tttgataatt gactatccat cttgatttct ttctaaaacg taatgattct
    17341 attatagcaa aattacctcc ataaaaaaag aaaaccaaag gctaggcttt cgattttcca
    17401 taagtatttt gatagtactt gcagtaagac tgaacgggac aaatctcaca ttttggtttt
    17461 ttggctaaac aatggtagcg tccaaagaaa atcaatcgat ggtgagtaat aatccaatct
    17521 ttctttggaa ttttagccat caaatctgct tcaatctgct tgacatcggc atctggtgat
    17581 gaaatattga gcctctttga gactctagcc acatgagtat caaccgcaat agctggaaca
    17641 ccataaacct ctgccaatac cacattggct gtttttcggc caacacccgg taaactttca
    17701 agttctttgt gggtttttgg cacttgaccc ttaaaatcat cacgaatagc ctgagcagtt
    17761 ttaatgatat ttttggcctt atttttatag agtccaatcg ttctcagagc attttcaaca
    17821 tcagaaagtt cagcaaaagc taagtcttct atttctggat aagactgcca tagtccagga
    17881 gttaccttat tgacggcctt atctgtcgtt tgagctgata aaatcaccgc aatcaacaat
    17941 tgaaaaggtg tttcccagtc taactctccc ttagcctcag gaaacatttg accaatgatg
    18001 gtcaggactt ttgctaatct tgcttttcca attctcatga atcactccat aaattcatcg
    18061 cagatagaaa atcctctgat atcgtcactt gagaaagatc ttcgccttct ctaacacgtc
    18121 tacgttcttc tacttgtcga agattaacaa taccttcttt tcgccaatta cgtaagatag
    18181 cctggatata tttccaattt gttttgccgt tgaagacagc ttcttttaaa gcttctcgta
    18241 tcaaatcagg atctgtttta tcatcacgaa gcgttttttc aagatcttct aactcaaaag
    18301 gactcaagaa tcgtcctaat tcacgttcaa attcatcaac taatcgtttg aaatgatttg
    18361 gtgtttcttg tttgtcaatt tcagttgccg tttgactgac aaacaattga tctaacttgg
    18421 ctaacacagg actcgcatca aaaataattt caatttctcc agtaagttca attgtccgca
    18481 tatctaaaag cccttgacta gtcaaagatg aaatgatttt attaatatca gcaactgatt
    18541 ttccaagcgc atgagcaatt tgactgggcg ctaagtcgtc tcgctttgtc gtattttgaa
    18601 gatagaaaaa ctgccagacc aaaaaatcat ctgagctctt aaaaagatct ttgtaatgaa
    18661 aaagcaaggc acttgggata accaaattac ctgacttata atgttctaaa aaactcataa
    18721 tccctcaatc aaaaggctaa aatcgaatct atagccttta ctactttaaa tcccctaatc
    18781 agatgctgat taatgtgctt acccaggaaa ctgcattaag actttatagt catagttcct
    18841 aatagcatga cgaccattta aaccttctaa ttcaataagg aaggcacaac cagctacaat
    18901 accaccaagt ttttcaatca tttcaatagt tgcttttacc gtaccgccag tcgctagtaa
    18961 atcatcgaca atcaaaacac gttgtccagg cttaatagca tctgcatgca tagttaaagt
    19021 atcaagacca tattcttttt cgtaatcggc agagacaaca tctcttggca gttttcctgg
    19081 tttacgaacg ggagcaaaac caattcctaa ctcaactgca acaggacaac caatgataaa
    19141 accacgcgct tcaggtccaa caaccatatc aatatcttta tcacaagcgt actgtgctat
    19201 ttcacgaata gcatagctat atgctttacc gtcagccatt aaaggtgaga tatctcgaaa
    19261 cgtaatacca gctttagggt aatctttgat cgatgcaatg taatttgtta aatccatagt
    19321 taattctttc tagtggcaaa ttgccaaata taaaatactc ttcattatat cacgaaacat
    19381 atttttcgta aaataagact tctgacatta ttgtttatct gatacttcat tcgtaactac
    19441 ctcaataact actgtcaact gctttactta ttgatcgttt gatttcacca aataatcata
    19501 catctctttc gggctagcca aagccatgat ttcttgaaat ttcaccaatt cttttaagtc
    19561 ttggtaaatg tggctctctg aaatctctcg tttttgcgct tgggggttaa ccgtcatcag
    19621 cccatcgtca atcgtcacaa aagacaactc ttcaaaaatt tgaatcaact taatcagtaa
    19681 aagtttttct atgtttaaat agtgactcaa ctctgtcaat ttatgccgta aatcaaattc
    19741 aggaaactgg tagatggttt tgtagagctt ggcaaactgc tctctgctgc caaatcctgt
    19801 taaataataa ggatgtttca tctgattttt aaaatagatg gcgtcaaaat ccttgtgaac
    19861 aaactggttg cgccaggttt tgaaatcttc agggatgtca ttaatcagaa tgactctggc
    19921 atttgggtct tcttcaatag tcggaatacc ttcaggaact ttggctgttt ttgtccttaa
    19981 gtcaagaagt tgcactccgt caacacgagc atctactaac atgaattgga gactcgtgtt
    20041 cccattccaa tggttgacag ataaggtaac tgctaattct aaaccagtag cttgtcggaa
    20101 ctcttgcagt tgacttcctt gaccaaaagc cagtacgtca aaggaagctt tgccctgact
    20161 gactttaaat ttaagatggc tctggtcttg ccctatggta cgcgcttgac taacccttat
    20221 gtccttgaca taaaagaccg gcttttgatg atccatccca taaggggcta atttatctaa
    20281 actctttaaa atatcaaggc taaggtcgtc caaagacagt ctttcatcaa tagttaacgt
    20341 atttttggca gtctgatcta agccacgttc tatcacaaac tgacaaagaa agtctgaaag
    20401 agcttccaag ttgtcaacgg gcagggtcat tcctgctgca ccagcatgtc ccccaaaggc
    20461 tgtaaataac tcacgcttgc cattcaaggc ttcaaaaata ttaatagctt ctaaacttct
    20521 ggccgagcct tttgcaaagc cattatcaat ggtcaaaacg acgaccgttt gtccaatagt
    20581 ttccatgata cgaccagcga caatcccaag aacaccagga tgccagccag cttgtgccaa
    20641 gacttgaaca ggtttttgag gatcaaccat agccatcgct tgatcaaaaa tgtcttggac
    20701 taaggcctta cgctcttcat tttttttctt aatcatcaag gcaatcgctt gagcttcttg
    20761 gtcatcaaag cccgtcagta gctcaatggc tggattaggg tcatctaagc gccctaaagc
    20821 atttaattgc ggagcaatct gaaagccaat ggcgtcttca ttaaaatgtt ccaaatcaat
    20881 aggagacaag gacatcaact cctgcaagcc cactctttcg gtgtgtttga gcatggccag
    20941 accatttttg actaaaacac ggttttcacc tgtcaagctt accatatcgg caatggttcc
    21001 aatagctacc aagtctagac agtctgttgg taaactttct agcaaagctg ttgccaattt
    21061 aaaggcaacg ccacagccag ctaagtgttt aaagggataa tcagcatcag gatgctcagg
    21121 atgaatgatg gcaaaggctt ctggcaattc ttcaggcagg ctatgatggt cagttacaat
    21181 gacatcaact tcctgttctt gagcatatct aatcgcttca tgtccggcca cgccattatc
    21241 aaccgtgata attagggaca cagcttcctg ctcaataaaa tatttataga cgctctggtt
    21301 ggggccatag ccatctgtaa agcggttggg aagataaacc aaaggctctg ctcccatcat
    21361 gtctagggtt tctttgacaa tagaagccga cgtcatgcca tcagcatcat agtcgccgta
    21421 aatgagaatt cgttcgccct cttcaatagc ttgacgaatt cttggaacag cttttgccat
    21481 gtcatgtagc aagtaaggat catgcagttg agacaagtcc gctgttaaaa actcatctaa
    21541 ggcttcttca gtccttatcc ctcgatcata aatcaactga gcggcggtct gggttagacc
    21601 ttttgtcttt gctagcttaa agaagccatc atctggcttc ttgtctttta ttttccagct
    21661 atatttggat ttaatcattt ataattaaat acctttcttg caagataatc agataattta
    21721 gggaaaaggg tgtaaaattg atgggtcacc gctaaactaa agggcaaatt caattctcgt
    21781 ttatttttcc cgataataga aaccaaacgc ttagccactt gatttggttg gagagtaaat
    21841 gtaccaacgc tttccaaata atgtccagac gggtcagctt ggtcaaaaaa cttggtggca
    21901 atgggacctg gattcacggt ggtcacgtaa acccctttat ccgctaattc taagcgaagg
    21961 gcattggaaa atccgataag ggcaaacttg gtggctgaat aaatgctcga tttggctgac
    22021 gcaatcaagc ctgccatgga cacaatatta ataaggtgac cttgcccctg ctctgccatt
    22081 ttctgaccaa tcaagcaagc aaagtgaatg ctcgctaggg tgttaacctg aaacatatca
    22141 gctatttctt gggcagaaaa ctcttcaaag cctttgaaag ctccgtagcc agcattatta
    22201 atcaagacat caatacggcc atagcgctgg taaatctggg cgaccatttt ctcaatggct
    22261 actggattgg taatatccaa ctcaaggcat tctttgttgt caatatgctg ataacagtgt
    22321 tctaggcgtt ctttgttacg tcctaataaa atcaagctgt cttccttggg taactgctta
    22381 acaattgcct gagccagtcc tccagaagct cccgtgataa caatgattct ttgtgccatt
    22441 aaataatcac ttcctctaaa tcttgtacca ttttaacatt ttcaaatata gtggcggcat
    22501 ctttttccat ctggcgacaa tcacgcccta aaaagcgagc tgatacatga ttgagcaaga
    22561 ggcgttttgc gcctgcttca tgagcgattt gtgctgcctg catgttggta gaatgcccgt
    22621 gatttctcgc aatccgctcg tcacccttac cataggtgga ttcatgaacc aaaacatctg
    22681 catctttagc gagtttaaca ctggcagacg ttttgcgcgt atcgccgata atggtgatga
    22741 ttttgccttt tttaggggca gaaatataat ctttggcaca aatcaggcgg ccgtcttcca
    22801 actcaacgtc ttgaccattt ttaattttgc caaagagtgg tccaaaagga acacccgctg
    22861 cttttaaggc ttctgcgtct agggttcctt ctaagtcttt ttgaactact cgataaccca
    22921 tgcaaaaaat ggtatgcgcc agacgctctg catagacctc aaacttatct gtttccatta
    22981 ttttacctaa tgatttgtca tcaaattcat gaaaatgaat ctgataaggt acacgcgctc
    23041 cagaaacttt tagactagtt aacacgtaag ttttaatgcc aattggtcca taaatatcaa
    23101 gatctgtctg ttcttcacta gcttgaaaag accgacttga taaaaatcct ggtaatccaa
    23161 aaatgtggtc cccatgcaaa tgagtaatga aaatctttct tatttttcgt ggcttaatcg
    23221 tcgtttctaa aatttgtctt tgcgttcctt caccgcaatc aaacatccag acttcattga
    23281 tttcgtctag taatttcaag gcaagacttg acacattgcg ctgcttggct ggttgaccag
    23341 ctccagttcc taaaaattgt aattccattc aatctattct ttctattggg tgatgtaaat
    23401 cataaattct cgttgggcaa aatcataata cttttgacca gaaaatgttt ggctaagagc
    23461 ccataactcc tctacattaa accccttaag catggtgata ccgtttgcca gacggtaaat
    23521 cttcgacaag agtgtgtcat caggcgtaat gtcttcacat tctccttgct caaactgctt
    23581 agcctgcatt ttaagctggc ctttgtcttc ataaaccata tattgtggga aaatttgtgt
    23641 taattcaaag aagagttcgg gtttcttagg ctctgctttt tcagaaaata ccaatgcaac
    23701 ttcttggtca ttttggtaag caaaaccata agcttttcca gacaaattga ggcgtacaaa
    23761 gggcttttct tcctcaaaag atggttggtc agtaaaaagc cccaaagcct tagaaagatt
    23821 aaaataataa tcagtcgcag cttgcggtga ctgtttttgg tagatttcag caaagtaggc
    23881 attaataaca cttggtggtg gtgtgataaa agctagtttt tgctggtctg tcaaactggc
    23941 taatagatgg tttaggtagt tggtatccag actagtaaat ccaccatagg tttttgctaa
    24001 atcaatataa ttattcataa aaatcgtcaa gtctccattg ctgttttggg gaaatgtagc
    24061 ccgaaatatc ctctatttct tggtcaaacg tgtagtggtc taaaagagca actcgattca
    24121 aatcatacag cttgtacgcc ttgtcttgat gcactttgat tctaaaagga acaaactggt
    24181 ctcgaatttg gtcaatgatt aaacgtctca agagaatttt gctatccttt gaacgggctg
    24241 aaatcctgat atttggaaaa gcagtagctg tgaattgttc tgctatatcc accttgttat
    24301 aaatagctaa acgcggaata ttaagcatgt ctagctcttt tagaaggttt aaaaccactt
    24361 tttcttgctc actatgattg gggtcgctag cgtcaatcac atgtaacagc aaatccacat
    24421 atttgctttc ttctagggtt gatttaaaag cagccactaa ttccgttggc aagtcttgaa
    24481 taaagcctac ggtgtctgtt aaggttgctt gaaattgatt ttctaaatag agttgctttg
    24541 tagttgcatc taaggtagca aataattcat tggcttcata gtggctgtca tctgtcaaca
    24601 agttcataat ggttgacttg ccagcattgg tgtagccaat caagccaatt ttaaaggtat
    24661 ctgaacccac acgacgttct ctaattgttt ggcgattttt ctctacctga gttaattggc
    24721 gttcaatatc agcaatctga tgacgaatcg aacggcgatt taactctagt tggctttcac
    24781 ctggtccacg gctcccaata ccacctgctt gacgacttaa catgatgccc tgtccaacca
    24841 aacgaggtaa catatatttc aattgggcaa ggtgtacttg taatttgccc tcatggcttc
    24901 tggcacgcat ggcaaaaata tctaagatta actgcatacg gtcaatgact tttacctcta
    24961 aaacagcttc tagattagca ttttgcctag cagtcaaccg attgttcaca ataactgcat
    25021 caatctcatc agcttccaca atcgccttaa tctcatccag tttccctgag ccgataaagg
    25081 ttttgctgtc gtaacgttct cgtttttggc tgaaacttgc cataactttg acaccagctg
    25141 ttttggcaag attagctaat tctgtcatgg acatgtcaaa atgttctgtt gtctgaagct
    25201 caactcctaa aagaatcact ctttcttgct gacgctttgt ctcaatcatc acctttacca
    25261 atcctccaaa ttccgtaaat tctattataa catatcttca acagattctg ctaattttgc
    25321 gtcatgactt ctctttctga ccaagaaaat ccctgaccct atcatgtact acctgtgggt
    25381 aatcaggagc cgttatggca gtgaagctaa cagccattcg attgcggaac caagttagct
    25441 gtcgcttggc aaaacgtctc gtgttttgtt ttaattgatc actagcttct gccaaagtca
    25501 tttcacctac aaaatagggg aataattcct tataacctat gccacgacta gcctgaacag
    25561 tcgggtaatg ctcatataac cattttgctt cttccaataa gccgttttca agcatacgat
    25621 tcacgcgctg attgatacgg tcatagatga cttggcggtc atcattcaag ccgataataa
    25681 gcggctcata agccgtctcg gcattctcta attcatcagc aaactgagcc aattcaaggg
    25741 ctcggatcgc ccgtctgcga ttcacctgct caatggtaat gttattgact tgcaagcgtt
    25801 catacaagtc gtgatcgtcc aattgctcca actcatttcg ataggctttt accgcctctt
    25861 gatcaacttg acctcctaga tgataacctt cgagtaaact ttgtaagtaa agaccagttc
    25921 cacctacaat aattggtaat ttcccacgac taacaatgtc tgaaatagct ttttgagcat
    25981 cttggacaaa atcgtaggcc gaataagact ccgtcacctc acgaatatca attaagtgat
    26041 gaaccgctgc ttcttgctct tcttgagtgg ccttggctgt tccaatatcc aactgtcgat
    26101 aaacttgctg gctatctcct gaaataattt ctccattaaa agccttggct aaactaatcc
    26161 caagtgctgt ttttccaacc gctgtcggac caacaatcac aactattttt atttttgtca
    26221 ttttcttgtc tttctattag aaaagcgtgt ccaaaaacgc cttttacttg aaaattagct
    26281 tatttttcgc taccatatat tataacataa gattaaggac cactgaggtc cttcactaga
    26341 aatggagaat aatcatggtt aagaaatatc aatttgttaa aggtcttgct actggcgtcc
    26401 tagcaactgc tgctactgtt gctggtgctg tctttgctgt aaaaaaaaca atcattgacc
    26461 ctgaagaaga aaaagctgct ttcattgaag aaaaccgcaa aaaagctgcg cgtcgtcgtg
    26521 tagctcgcta acgtgacaat ggatcaattt aaaagagact agcacattaa agtgccggcc
    26581 tcttttttag taatctcgat aactagttag tagtaactgt cttttgatga gccaagatat
    26641 tagctgcttt acttattttg aaatagaaat ctcaggtaag ccccataaac ataagtgact
    26701 aaagctgtcg ccaacaatac ctctcctagc aaaagaacct gccaacctaa accttgccaa
    26761 cctaaaaaag ataaggtcat ttttaaggaa gtggcactaa tcacaaacgg aaaggtaaaa
    26821 gctgaaaaac ctgggttaaa gggacgattg agtaagcgag gaagctgtac aaccacaaaa
    26881 gcatataaca gttgtgagct gatgagaaga aagataacca ttcctacttg tggtctagga
    26941 aaggttgcta aataagacgc tgaaagtaaa gacagagggg cacaaaacgt tgaaatatta
    27001 ggcattactg cttgacctag accaatccca taagtctttt tggccataaa aggtaaaatc
    27061 acagcagtta ggggaagaca aacccaaaaa atcacctgtc ctaataaaaa ctgcctacta
    27121 gcaggtgctg ttaatgccgc cattgcaatt ccaacaaaaa gcacggacca ggaaggaaaa
    27181 acgttatccc atgaaaaaga aaagacaaaa cgatactggt aataagcaat caggacaaga
    27241 tttcccaaaa agaatagcca ccaagtgaga aagcctaacc aacaccctcc tgtcactttg
    27301 agaaagagtg aagacaacaa cacccctgtc ataaaaaaag ttggaaaaac agaggcaatt
    27361 agaggttgtc gtaactgcat tttggtatcg ttaagattcc taaccatgcc aacaagcaag
    27421 ataccataga taaaaagagc tgccagaatt cccaaataac taaaaatcga aacataagta
    27481 gccaacaaat tgccaaatga caacgttcct aatgccaatc ctgacatgac caatggtggg
    27541 tttttaaggt gtttcataag tgtccttttc tgcctattaa cagctatttt tagtgacata
    27601 atcttgttta ttttatcaca tttcgagcat ttttgccata aaggctgcca gatgc
//
LOCUS       DAUGUF010000025        25610 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUGUF010000025 DAUGUF010000000
VERSION     DAUGUF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25610
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.025"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            2..676
                     /gene="speC"
                     /locus_tag="VIB71_001147"
     CDS             2..676
                     /gene="speC"
                     /locus_tag="VIB71_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeC"
                     /protein_id="HEQ8822882.1"
                     /translation="MITVILISTISPIIKSDSKKDISNVKSDLLYAYTITPYDYKDCR
                     VNFSTTHTLNIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLFYILNSHTGEYI
                     YGGITPAQNNKVNHKLLGNLFISGESQQNLNNKIILEKDIVTFQEIDFKIRKYLMDNY
                     KIYDATSPYVSGRIEIGTKDGKHEQIDLFDSPNEGTRSDIFAKYKDNRIINMKNFSHF
                     DIYLEK"
     gene            complement(744..1949)
                     /locus_tag="VIB71_001148"
     CDS             complement(744..1949)
                     /locus_tag="VIB71_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEQ8822883.1"
                     /translation="MTFLDKIKQGCLDGWAKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFNTKTQEEYQAGVITDIVDRFRAYDSWDESIADHGQFLVDNPRYQ
                     SVIGEADYKKACHAIKDAGYATASGYAELLIQIIEENNLQKWDKEAIVRKEKQMINSQ
                     CREVIEFFINLANAGMGVDKDSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAAV
                     GWEVHRMPTDANPLTGAFFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALY
                     VGAPARFNTRDFTGVIGWFYPPYQGDTVTQPVSTEPQTSETIVETAKTGTFTLDVAEI
                     NIRRWPSLASEVVGSYKQGDTVSFDNEGYANGYYWISYVGGSGMRNYLGIGQTDKDGN
                     RISLWGKLN"
     gene            complement(2065..2292)
                     /locus_tag="VIB71_001149"
     CDS             complement(2065..2292)
                     /locus_tag="VIB71_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEQ8822884.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKK"
     gene            complement(2289..2564)
                     /locus_tag="VIB71_001150"
     CDS             complement(2289..2564)
                     /locus_tag="VIB71_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822885.1"
                     /translation="MATELIFGVGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHAEQNKTLITMTEQIKNLTDDVKDLKDMMRGEIK"
     gene            complement(2574..3191)
                     /locus_tag="VIB71_001151"
     CDS             complement(2574..3191)
                     /locus_tag="VIB71_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8822886.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQLVKQDLIS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHMLMSGGKIDSDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEAFEYDKQTLEELESEAKVTVIKYADLVKQD"
     gene            complement(3194..3625)
                     /locus_tag="VIB71_001152"
     CDS             complement(3194..3625)
                     /locus_tag="VIB71_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ8822887.1"
                     /translation="MDLTLKNKELNTLYRVLDKIKITNMRANRGRAKLLAKVVDKINE
                     YAKDETDLIDMYAAKDKDDKFVIDEHKNIKLADPAKLDELNDLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGE"
     gene            complement(3637..5523)
                     /locus_tag="VIB71_001153"
     CDS             complement(3637..5523)
                     /locus_tag="VIB71_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8822888.1"
                     /translation="MSRDPTLTLDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRRLS
                     SSYQSGINGLKAQLANDKIGLQAEIQATAQGLSQKYDNELRQLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGMRIELESQISGLRAVQQSTASQISQEIRDRTGAVSRVQQDL
                     ESYQRRLQDAEDNYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLSSAKMDFNSNATINFNSRDNALVRRDDTHTAFVHFSNATPKGYTGS
                     ALYAAIGITSSGDGVNSASSGRFAGMRCFRHATGYNHTAAVDQTEIYGDSVLIADDFS
                     INRGFKFRPDKMTKVLDMNDLYAAVVALGRCWKHLANVGWNTVHGNFTNAVTNELNNH
                     INKI"
     gene            complement(5536..6546)
                     /locus_tag="VIB71_001154"
     CDS             complement(5536..6546)
                     /locus_tag="VIB71_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ8822889.1"
                     /translation="MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGD
                     GKNQFSKLKYLNKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNL
                     KGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRT
                     GKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKAL
                     GTLKITHENPNVEANYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIR
                     NLGDDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVKKLKALLMDK
                     QV"
     gene            complement(6543..8687)
                     /locus_tag="VIB71_001155"
     CDS             complement(6543..8687)
                     /locus_tag="VIB71_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8822890.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVNGASVGAESALEIWKKNLVGDDKFDVKSDILTLGSFSWEADKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILRKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEAPGKPHVGEHKQPEEQLVTLPEFILDGQYLSLYAQRRIQMVDLSSHFN
                     DDKNKKEPTVEEIRKLAQKYLKDNNVGAPKVSIEVDYIDLSQTLDYQDFRVMEEVELC
                     DIVPLYYPKFGITTESEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVSERINAL
                     ENNQKVITNNQKQFELNLPKYLNDINGKRVWYEKPDDNIEHKIGDYWFEKNGKYQRTW
                     IWDGNQWVKVLDTEDLNPNQRAFDEAMAEIEKAKKAQEEINQRTDKELEEFRATLKNL
                     ALPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEILGNNGKTRYNKN
                     LLVGDPNRTKTYDEDYIEVEANDGGFKRGETYTISFSQTCELLQKVAITLTQANNKGV
                     KLVLTPTKAKTDAQTFEVTKDKQSIEVYPLSYTGVLTGDWYKPKQIDLNASDTQELAL
                     EMAYKEVVDGKDAAITGIWSDSPQIILDGGKK"
     gene            complement(8684..9391)
                     /locus_tag="VIB71_001156"
     CDS             complement(8684..9391)
                     /locus_tag="VIB71_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEQ8822891.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDVDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTANQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKINFLIHPIKYLKTGKQEVSLVNGSTLQNPGNVQAKPILKIKGIGN
                     GVLTINGFKTGLENVQGELVIDMERHLVYKDVLSAWDNIVRTERHRMPLFDVGQNKIS
                     WTGSFTITAVPNWGVKV"
     gene            complement(9391..13314)
                     /locus_tag="VIB71_001157"
     CDS             complement(9391..13314)
                     /locus_tag="VIB71_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEQ8822892.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAQVAELQNRLRALATETSVFTRFGKAAERIGGKMKSFGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYESAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIDLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWKENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSILGKGIGVIGGTIQAIGKMSKGIGALSGWLRTFKAGA
                     VAASVGAEAATASMGSLTGAVALLSNPVTWGVLLGGAAVIGIGLIADSMYKAQKRTEE
                     WGTAVSATEATALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMIIAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHRGISQMASDMAQKLGISYDDAYRKMAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWQNMTLEQKKLVVDGQQAMIEIFDSKELLAQWQVLTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNATDKTAGDTQSAQSKIDNVKQKAPADMKAS
                     DKTGPDVASANRAVNSPKQNSPAVIRAQDNASGVAENVIWSLARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAVVNDQKGALYRELVTLPTGESFIPTGRNVILPLPRGSKVLK
                     ASRTKQLFPHYANGIGFDDTRIASLTTRLKSVQDKGTVVVNADPQLAELIKLLKDRDD
                     RNVTNNYTLNATNSSSSEDMFSQENMRRLVRELAYYTKGEEGRLA"
     gene            complement(13327..13476)
                     /locus_tag="VIB71_001158"
     CDS             complement(13327..13476)
                     /locus_tag="VIB71_001158"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822893.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            complement(13524..13850)
                     /locus_tag="VIB71_001159"
     CDS             complement(13524..13850)
                     /locus_tag="VIB71_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822894.1"
                     /translation="MYEITLKKGGVDKEFKKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMTVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            complement(13903..14511)
                     /locus_tag="VIB71_001160"
     CDS             complement(13903..14511)
                     /locus_tag="VIB71_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8822895.1"
                     /translation="MGKVKFGLRDFYYGVLDGNDKVTKAESIKHLPGMKSAKLDITNE
                     LVTVPADDGPYVVLSGGISETKLEIELLDLTSDARKDFFGITVEKGVEKYNKNLTPND
                     IVCLFRTSDENGKAIWIALLKGKFNLPGMEAQTKEGAPDPKPDTTTGNFVARGPKEEV
                     LLVGREGNSGFNLNEFLKCVFAGCGDAEIKKIPIAEQASTVM"
     gene            complement(14527..14952)
                     /locus_tag="VIB71_001161"
     CDS             complement(14527..14952)
                     /locus_tag="VIB71_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822896.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGTFKNGFKQGIFTYDIPD
                     NPVNLRKVELAPFMRINTTLDGPFDYADDEILCNEQRITINFWCKTASEADQINKCID
                     NILKQGGFERYTANEKPRYKDRDIDLLMNVRKYRYFDFY"
     gene            complement(14949..15326)
                     /locus_tag="VIB71_001162"
     CDS             complement(14949..15326)
                     /locus_tag="VIB71_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ8822897.1"
                     /translation="MTKGLDEILANLTKLEVKASKTAKAAVTKVAKEFEKTLKSNTPV
                     YEIETDERLQEDTVISGFKGSNVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKER
                     TINQMTPRARQIYAEKVKEGLGL"
     gene            complement(15323..15670)
                     /locus_tag="VIB71_001163"
     CDS             complement(15323..15670)
                     /locus_tag="VIB71_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEQ8822898.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAIRKDLYTCWAEVLKTQ
                     LRDFNYQSKFQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFDKRIYKIDKIESDES
                     GKDMIMISGVSMS"
     gene            complement(15667..15969)
                     /locus_tag="VIB71_001164"
     CDS             complement(15667..15969)
                     /locus_tag="VIB71_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ8822899.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFEDDIIKEMIESAQEQICFAIEEG
                     STAGTFKESAKFALAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            complement(16114..17301)
                     /locus_tag="VIB71_001165"
     CDS             complement(16114..17301)
                     /locus_tag="VIB71_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEQ8822900.1"
                     /translation="MFEEKIKEIKATIASLNQAIATKTAEVKNALESDDLETARSIKA
                     EVEQAKADLVEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPIDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQCATEKMVSVEELEKNPKLAKPKFKDVEWKVETYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEPKADVKTLDEIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSVTGKVFLGKPVFVLADEVLGKN
                     KAFVGDFKRGVLFADRKDLGLRWVDNDIYGQYLQAVLRFGVAKVDDKAGYYVTFTPEQ
                     LPS"
     gene            complement(17326..17991)
                     /locus_tag="VIB71_001166"
     CDS             complement(17326..17991)
                     /locus_tag="VIB71_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEQ8822901.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDI
                     ILEVNSNGGLVTVGSEVYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFNWVAGNSDDLDKASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEIL
                     QGL"
     gene            complement(17969..19189)
                     /locus_tag="VIB71_001167"
     CDS             complement(17969..19189)
                     /locus_tag="VIB71_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8822902.1"
                     /translation="MSFFRPLGSSKVSYDDYISSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDSHEIIYTFTDTLTAKQVKCFAHDVVHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILTMKGAQLSGDARQR
                     ARQEFEKMREGSIGGSPLVFDSTMEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLNDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLIELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            complement(19223..19447)
                     /locus_tag="VIB71_001168"
     CDS             complement(19223..19447)
                     /locus_tag="VIB71_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822903.1"
                     /translation="MNKRIKKKRKLETAIVLLIKEVAELRSIVSANAKATNNELAAVK
                     SAILDNQVAIKSIGDEVGHIKQNYKRKWRK"
     gene            complement(19440..19610)
                     /locus_tag="VIB71_001169"
     CDS             complement(19440..19610)
                     /locus_tag="VIB71_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822904.1"
                     /translation="MIDFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIVL
                     AIYVDSVGGKRE"
     gene            complement(19607..21361)
                     /locus_tag="VIB71_001170"
     CDS             complement(19607..21361)
                     /locus_tag="VIB71_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEQ8822905.1"
                     /translation="MKVEYDYSAISDIYKDDAFYYAKMVVDEQIKSSKKVFRACLRHL
                     NDLKKIDGDNFKFIYLPEKAADPINFIEILPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDGEIT
                     DEGYFGYVAEQDNEEEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKTTWELARIDKPDTNKRRVWLGVDVGRVSDLFAITPVVM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLECQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEINGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KKGKIKHSGNPLLTMAINNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTNEKIIGGESLF"
     gene            complement(21365..21595)
                     /locus_tag="VIB71_001171"
     CDS             complement(21365..21595)
                     /locus_tag="VIB71_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822906.1"
                     /translation="MERVKEFSVKLLENGKFPIVEINGEKINGITKLIVKYDSDDAQN
                     NPLDNGFLVEYISEEGGRYYMQTIGQSFRIGL"
     gene            complement(21598..22065)
                     /locus_tag="VIB71_001172"
     CDS             complement(21598..22065)
                     /locus_tag="VIB71_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEQ8822907.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            complement(22236..22574)
                     /locus_tag="VIB71_001173"
     CDS             complement(22236..22574)
                     /locus_tag="VIB71_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEQ8822908.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDKQAKQFYN
                     SRIWRETSKQVLLQNDYICAMCGGEATMTDHIVSVKQDWNKRLDWNNLQASCKACNDS
                     KAIRERRKNN"
     gene            22810..22995
                     /locus_tag="VIB71_001174"
     CDS             22810..22995
                     /locus_tag="VIB71_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEQ8822909.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPMHNK
                     DLGKGLEDTILKQAGLK"
     gene            23047..23424
                     /locus_tag="VIB71_001175"
     CDS             23047..23424
                     /locus_tag="VIB71_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEQ8822910.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGEDFQEAYEMAVEVLG
                     FALEDYTDYPKASAVSDLKEQYPDSDIALIGIDMVAYMKKYHSKKVRKNVTIPEWLND
                     AAEDKNLNFSQVLTEALELKLQA"
     gene            complement(23551..24444)
                     /locus_tag="VIB71_001176"
     CDS             complement(23551..24444)
                     /locus_tag="VIB71_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEQ8822911.1"
                     /translation="MLKLDEKKIRKGKPVGLPYQGSKKKISKKIVEIIKQNFDADKPI
                     YDVFGGGGAITAECVLNGLEVHYNDLDNDITDMFQRVISQDREWIKTLIISRDEFNKI
                     RQKEPKSVDDNLKLLVNSFGNELSSYLYGADWSDTKYDLAVEIINKHDVFSGYKQTET
                     YKKADKPYDEGELEKNKKLTQLEQLQQLGRLQQLGRLEQLEPTNYSYEAFSDIEDAIF
                     YLDPPYENTTQKSYKGDFNSQAFYDWAFGMSKNNIVLISSYDISDERFECVYEFKTAR
                     STMQGGGAGKRTEKLFMAVIT"
     gene            complement(25027..25464)
                     /locus_tag="VIB71_001177"
     CDS             complement(25027..25464)
                     /locus_tag="VIB71_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ8822912.1"
                     /translation="MGNIPTTKANNFLEELKTIPHLIETLERDANLMSRSLVKSPQWS
                     DMKVSGGVKQSQEDKNIKMLHMVGYYSDQIEQLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
BASE COUNT         6851 a         5728 c         4408 g         8623 t
ORIGIN      
        1 cataattaca gtcatactga tttctactat ttcacctatc atcaaaagtg actctaagaa
       61 agacatttcg aatgttaaaa gtgatttact ttatgcatac actataactc cttatgatta
      121 taaagattgc agggtaaatt tttcaacgac acacacatta aacattgata ctcaaaaata
      181 tagagggaaa gactattata ttagttccga aatgtcttat gaggcctctc aaaaatttaa
      241 acgagatgat catgtagatg tttttggatt attttatatt cttaattctc acaccggtga
      301 gtacatctat ggaggaatta cgcctgctca aaataataaa gtaaatcata aattattggg
      361 aaatctattt atttcgggag aatctcaaca gaacttaaat aacaagatta ttctagaaaa
      421 ggatatcgta actttccagg aaattgactt taaaatcaga aaatacctta tggataatta
      481 taaaatttat gacgctactt ctccttatgt aagcggcaga atcgaaattg gcacaaaaga
      541 tgggaaacat gagcaaatag acttatttga ctcaccaaat gaagggacta gatcagatat
      601 ttttgcaaaa tataaagata atagaattat caatatgaag aactttagtc atttcgatat
      661 ttatcttgaa aaataattca tcatacacaa aaaaccgccc agaataatct gagcggtttt
      721 gtcttatctc ggagctttac ctcctaattt aatttacccc aaaggctgat gcgattccca
      781 tctttatcag tctgtccaat acctaggtag ttacgcatac ctgagccgcc aacatagcta
      841 atccagtagt aaccgttggc ataaccctca ttgtcaaagc tgacagtatc accttgctta
      901 tagctaccta ctacttcact ggctaggctt ggccagcgtc tgatattgat ctctgcaaca
      961 tcaagggtaa aggtgcctgt ttttgctgtc tccacgatcg tttcagaagt ttgcggctcg
     1021 gtgctgactg gttgcgtgac tgtatcccct tgatatggtg ggtaaaacca acctatcacg
     1081 ccagtaaagt cacgagtgtt aaaacgagct ggtgcaccga catacaaagc atcaggattg
     1141 ccatcaatgt tttgctcgac agtgcgcatg gtgtaaccgt cactatcctc gataacaatt
     1201 cccgtatgtc caaattggtg atacggcact gattggacaa aaaatgctcc cgtcagtgga
     1261 tttgcatctg tcggcatgcg atggacttcc caacctacgg cagcagcgct atctagtaag
     1321 tcaatcgcat ttccccaaag gtcgacatcg aaccagtgct ttgctgcata acaaggcaca
     1381 tctgcacatt gccagcccgc aaaactatct ttgtcaacac ccataccagc attggccaaa
     1441 ttaataaaaa attcaatgac ttctcgacat tgagaattaa tcatttgctt ctcctttctg
     1501 acaatagcct ctttatccca tttctgcaag ttattctcct caataatttg gataagtagc
     1561 tccgcatagc cactcgcagt cgcatagcct gcatctttta tagcatgaca agctttttta
     1621 taatcagcct ccccaataac agactggtag cgtggattat ctactaaaaa ttgtccatgg
     1681 tcagcgatag attcatccca gctgtcatag gctctaaacc tgtcaacaat gtcagtaata
     1741 acaccagctt gatattcctc ttgggttttg gtgttaaacg acttaccggt ccagcttgcg
     1801 tctgccttaa taccaaacaa agcgttatgt ggtgcatgtt taccccaccc gctctctaag
     1861 atagcttgtg ctgcggtcaa ggatggcaag attttgtact tagcccagcc atctaaacag
     1921 ccttgtttaa ttttatctaa aaaggtcatc tgtcctcctt atctaaaaac ggataaaaga
     1981 taagagcaac cacagataat ggcacataca gtattgcgat tgctataact aatgctaatc
     2041 gtgtgattgc tcgcatggct cctcctattt tttgggctca tggtaagtca atgcttgttc
     2101 gctgtcagat aagccttttg tagtaggatc tgtgacaacg ccaagcaaca ccaaaagcgt
     2161 tacagctgtg ttggcaatat ccgcgatgtt tgatggtaat ttaataccta attgttgcgc
     2221 taacaaaaag atagctccca aaatagccat caaggttact ttgttttgta gtcgtaattt
     2281 taaattgatc atttgatttc tcctctcatc atatctttta aatctttaac atcatctgtt
     2341 aaatttttaa tttgctctgt cattgtaatc aacgttttat tttgctcagc gtgctcttca
     2401 agccgccgag cattttggcg tgtaacaatt tttaaatgct ctacctcaga ttgcaacaaa
     2461 gtaatatctg tcgcatgctt gatggatttt gcattaaaaa tattgtaagt cgtgacgata
     2521 gctaaaataa agccaccaac gccaaatatc aactctgttg ccataaacca cctctaatct
     2581 tgtttaacca aatcagcgta cttgataact gttactttgg cttctgactc tagctcctct
     2641 aaggtttgtt tgtcatactc aaatgcttcg ttaacgtgta cgaagactag gttcccttcg
     2701 cctgcttcac cgtcttcctc tttagtactg tcgaccaccg taaagacatc atacgcttga
     2761 tactcacctt ttttggctgg ctcgattagc tcaagcatgc ctttataaat gtcagaatca
     2821 atcttgccgc cgctcattaa catgtggatc gtttgtaagt taatcatctt ttgcgtgcgc
     2881 tctgcggaca ccttagctag tccagcagct gtttgagcag ttttggcagt cttagcggtt
     2941 tcctgtgaga ttttttcaag gtcgtctacc ttttgcacgg cttcgcccat tgcaatttca
     3001 acgtattcag attttttaaa ttcttccaaa gtagctttga taatctctgt gtcattagtc
     3061 gagattaagt cttgcttaac aagttgagag atgactgagc catcctcagc agtgataata
     3121 atatgtgtgc ttgcgactgc tcctgtgctg tcaaattgtg ggtattttcc tgtcactttc
     3181 caatttctca tggttattct ccttttttac tttcttcaaa ttgttccaaa atgttgtcga
     3241 taagaatgat ttcagatgat gtaaattcat cttcacactc ttctaaaaag tttaaaaagt
     3301 caataaatcg cttggagtac tcaccccctt taatcacaat ttcttcatct gctagctcgt
     3361 tgagtaggtc gttgagctcg tcgagtttag cggggtctgc tagcttgatg tttttgtgct
     3421 catcaatgac aaatttgtca tctttatcct tagctgcata catatcaatt aagtcggtct
     3481 catcttttgc atactcattg attttatcga ctactttggc aagcagctta gcacggccac
     3541 gattagcacg catattagtg attttgattt tgtctagtac acgatatagt gtattgagtt
     3601 ctttattttt taatgttaaa tccattgttt ctcctattaa attttgttga tatgattatt
     3661 taactcgtta gtgaccgcat ttgtaaaatt gccatgaacg gtattccagc cgacgttagc
     3721 taagtgcttc caacaacggc ctaaggctac tacggccgca tacaagtcat tcatatcgag
     3781 tactttagtc attttgtccg gcctaaattt aaagcctcta ttgatgctaa agtcatctgc
     3841 aataagtaca ctatcaccat aaatttctgt ttggtcgact gccgcagtgt ggttgtagcc
     3901 tgtagcgtgc ctaaagcaac gcatacccgc aaaacgtcca gatgacgcac tgttgacccc
     3961 atcaccagat gaggtgatac ctatggctgc atagagtgcc gaacctgtat aaccttttgg
     4021 tgtggcatta ctaaaatgta caaaagcagt gtgtgtgtcg tccctgcgga ccagagcgtt
     4081 atcacgactg ttaaagttga tggtcgcatt actattaaaa tccatcttag ccgagctaag
     4141 atcaataagc atagcgccat tacgagcttt gatgactttg ccctcgagca aatcagtgat
     4201 agcatagcca attttagctt tgataaagtt agcgtctaaa ccaacgatac tacttgcgtt
     4261 aaggttaatt actctaatcc tagcagcgtc aatcgtgcct gcaataatct gatcagccct
     4321 aatcttgata gcctctgcta tctttgtggt aaaggtgccg ttgacagtcg tattgccatc
     4381 gagagcgatg tgtttacctg cgattgttac tccgtaggag ttgaggttaa ttgctgagat
     4441 aatctcatta ccagacattt tggcattaat gccgccagcc ttttggatag ctaatttaat
     4501 gctgtctcca gcgccactaa taatactcat gacaccatct ctagtaaccc gctgctcaat
     4561 ttgtcctgct agttgagtaa ggcgtgattg gattttacca gtcggggacc ccacatcact
     4621 ctgcaaacct ctaactgtat gggttaagct actgtaatta tcttccgcat cctgcaaacg
     4681 acgctgataa ctctctaggt cttgctgcac acgactgaca gcacctgtcc tgtctctaat
     4741 ctcttgtgag atttggctag ctgttgactg ctgtacagct cttagtccgc tgatttgaga
     4801 ctcgagctct atcctcatgc cttgattact acgagtaaac tcagcacgta agcccgcaag
     4861 cttactctcg taggcctctg tagtgccgct tgaggttgtt gtgatcttag ccgataactg
     4921 tcttagctcg ttatcatact tttgtgataa tccttgagcg gttgcttgta tctcagcttg
     4981 taaaccgatt ttatcattgg ctagttgagc ttttaggccg ttaatgccag actggtaact
     5041 tgaggataag cgcctatcag catctcgata ctcacgcctg ataccatcaa tggtatcatt
     5101 gatgagcgct agctttttat cagtatcctc gctgatacgt gtagcgacac ctctggcgga
     5161 gttgactatc tcggtcttga tcttaccgtc gtagtattcc tgcaacatac cacggttagt
     5221 cagcttaatt tttgaccaaa gctgggaatt agcagtatct gtcagctcta agctaatctc
     5281 tttgaggtct ttaaatagtc cagtcggatt acctgtaccc tcaactacta ctggcgcaac
     5341 atagctagta gcttggtctc ctcgctcaat catgagctga ttaaaatgcg ctgtgcctag
     5401 acacttgcta gctagtctga cttttgggtt gtcgtcctct gcggtaaatg tgtaatgcac
     5461 acgtccatcc ttaccaataa cgagatttga ctcgtctaat gtcaacgttg gatctctact
     5521 catatttcct cctctttaca cttgcttatc cattaagagt gcttttaatt ttttgacttc
     5581 actatcaaca taagctttag ttgccgcatg atcatccgct gtgggattct tgagtttcag
     5641 gttgccatca atctgcgaag ttttcttggc ataaaaacca ccgtcatgct tgacgtagaa
     5701 cttatcatca ccaagatttc taatcctaag caacttccct gtcgttcctg aggttgagtt
     5761 aatgtagatt ccttgagcag cagtaccttt tccgcctttc tgttttttaa cgatatcaat
     5821 agataacgct gcagcgtttt catcgtaatt tgcctcaacg tttgggtttt cgtgtgtgat
     5881 tttgagcgtt cccaatgctt tttcgacgcc tctaatttgc atcgcactac cattttcatt
     5941 gccgctagta atattaagcg cagaggaaaa attgggggtg gttggctgac gcatcgcaat
     6001 attaacggca ttagtcttac cgctgtaatc gacaaaaagc gctgattgat tgaaggtctc
     6061 tttacccgtc cgcaagctca ttaacggccc atcactggta tcattgttag aatagacaac
     6121 aacaccagca ccttccgatt tagacatatc aatgttaatc gctcctccta cggaagatga
     6181 gggtttaata ccacttttat taggtttaaa ctgtagttga cctgtcatga cgccgccttt
     6241 gagatttaat ttcttgtcaa gctctatttt tgactctgct tttaagtaaa cagcgttttt
     6301 atctgctttg cttgattcta atttggtgat tttactatta gtttcttctt tttgtgcaaa
     6361 cgcacctaga tctggtttat taaggtactt aagcttacta aattggtttt taccatcacc
     6421 aaacttagca tatcctgtat cggtctcaaa gcctatttca ctctcaagta agatgacatc
     6481 gctgcgagtc cattcttcgg cagtcatccg cttaaattgg actcgtagcg gtatagtttc
     6541 tgtcattttt tacctccgtc taatataatt tgtgggctgt ctgaccatat ccctgtgatt
     6601 gcggcatcct taccatccac aacctcttta taagccatct ctagagccaa ttcctgcgtg
     6661 tctgaggcgt ttaaatctat ttgcttaggt ttataccagt caccagttaa aacgcctgta
     6721 taacttaaag gatatacctc tatagactgt ttatccttag tgacctcaaa cgtctgtgca
     6781 tccgtttttg ctttagttgg tgtcagcact aacttaactc ccttgttgtt agcctgtgtc
     6841 agcgtgatag ccactttttg gagtagctca caagtctggc taaagctaat cgtgtacgtc
     6901 tcgccacgtt taaaaccacc atcgttggct tctacctcga tgtaatcctc atcataggtt
     6961 ttggtgcggt tagggtcgcc aaccaataaa tttttgttat agcgggtctt accgttgtta
     7021 cctaaaattt cggcgtttag acgggacgtc tcgctcgttt cactgacttt gtttttgagg
     7081 tcatcaaagc tttgtttaat agacgggatg tcatcaactt tgatagcctc tgtgattttt
     7141 ttaatcgctt cctctggtaa cgctaggttt ttgagggtgg ctcggaattc ctctagctct
     7201 ttgtcagtac gctggttaat ttcttcctgc gcttttttgg ctttttcgat ttcagccatt
     7261 gcctcgtcaa aggcccgttg gttagggttt aaatcctctg tatctagtac tttgacccat
     7321 tgattgccat cccaaatcca tgtgcgctga tacttcccat ttttctcaaa ccagtagtcg
     7381 cctatcttat gctcaatatt gtcatctggt ttttcgtacc aaacgcgttt accattgatg
     7441 tcattgaggt atttaggcag attgagttca aattgttttt ggttgttagt aattaccttt
     7501 tgattatttt ccaacgcatt aatacgttca gaaacaccac cagtcaaact tttagagatt
     7561 gattgaccaa tcgtacctaa tttgattgtg tgattgctat ctgtatagac gtcatagaca
     7621 atctcaacta ctttttcaga ctcagtcgtg atgccaaact ttggataata aagcggcaca
     7681 atgtcgcaaa gctcaacctc ctccatgacc ctaaaatctt gatagtcaag cgtttgtgac
     7741 aagtcgatat aatcaacctc aatgctgact ttaggggcgc ctacgttatt atccttaagg
     7801 tatttctgag ccaactttct aatttcttcg actgttggct cttttttatt tttgtcatcg
     7861 ttaaaatgac ttgataaatc aaccatttgg attctgcgct gagcatataa gctgagatat
     7921 tgaccatcta ggataaattc aggcaatgtc accagctgtt cttcgggttg tttatgctcg
     7981 cctacatgcg gcttaccagg ggcttcctct tgcggttttg gttgtggcgt atatcttacg
     8041 taaggataga tagaggtgta attgccatct agcaagcgct cctcctctac gctgacgata
     8101 ttacggccat actccaatac cgtgggagct ttacgcccca tttgcttgcg taagatgatt
     8161 gtacggttgt caaactcgta ctcgccaccg taaacatcta ggatagagcc agcgacacct
     8221 cctagagcac cacgggcatt gccgatttta tcagcttccc agctaaagct cccgagcgtt
     8281 aggatgtcgc ttttaacgtc aaacttatca tcaccgacaa ggtttttctt ccagatttct
     8341 aaagctgatt cggctcctac gctcgcaccg tttacaaacg gttttaaagc aatatcctgt
     8401 gtgcgcatag agatatgacg cgcaaaaatc tcgatgtggt ctttactatt tcgtagtacc
     8461 cgattaatct caaaagtctg ccatttggtt ctacgaccag cgtcagactt aatcttcatt
     8521 tcctctttaa aaactgaggc aaagacacca tctagcggat atttgatgta cagtgagtaa
     8581 ttaccattgc gctcacgagt ggctttaacc tcataagcat ccgcaatctc accgagacca
     8641 aaagtcctaa acttggtttc cttagcctca tacaaaactg gtatcatact ttaacccccc
     8701 agtttggcac tgcggtaatt gtaaagctac cagtccacga gattttattt tgtccaacgt
     8761 caaataacgg catgcggtgg cgctctgtcc gcacgatatt atcccaagcc gacaagacat
     8821 ctttatagac cagatgcctc tccatatcta tgacgagttc tccttgcaca ttttccagcc
     8881 ctgtcttaaa gccattaatg gttaaaaccc cattgcctat acctttgatt tttaagatag
     8941 gtttagcctg aacattgccg ggattttgta gagtactacc attaacgaga gacacctctt
     9001 gcttacccgt ttttaagtat ttgatagggt ggattaagaa gttgattttc agtctgccga
     9061 attgttttag aatctcgtct atctcaaaaa gattgacaac actagcccga tagatatagt
     9121 ccttgtccca agacaaagct aagtcatgcc aacctttgac gtgcaaccat tcacttattt
     9181 tttgttgatt ggcagtcacg tcaccaacca gcgaaaaagg aaagtcttgc tcaaccgctt
     9241 ttaagcgttc gttgtcttta ataagtacac cgtcacgacc agctacttcg attaaatcaa
     9301 cgtcattatt tgtcgactta attgaccgct cgcgttctag caacaaacct aaatcattgc
     9361 ttttagttcc gttaaactca atgtatctca ctaagctaac ctcccttctt caccttttgt
     9421 gtagtaagct aattctctga ctagccgtct catgttttct tgactaaaca tatcttctga
     9481 actactgcta ttagtagcgt ttagtgtata gttgtttgtg acatttctgt catctctgtc
     9541 tttaagcagc ttaatcaact cggcaagttg tggatcagcg ttaacgacta cagttccttt
     9601 atcttgcaca gatttaagac gagttgttaa gctagcgatt cttgtatcat caaaacctat
     9661 tccatttgca tagtgcggga ataactgttt tgttcggctg gcctttaaaa cttttgaccc
     9721 tctcggtaga gggaggataa cgtttcgacc agttgggata aatgattctc cagtcggtaa
     9781 ggtaactaac tctctatata gcgccccttt ttggtcattg accacagcta acccgccagg
     9841 gtggaaatca gtcccttttt cgtgtccgaa aatcttacgg acaaacgttg taatggttgt
     9901 tgtaacactt cttgggattc tagccagtga ccatataaca ttttctgcaa cgccgcttgc
     9961 gttatcttgt gctctaataa cagctggact attttgttta ggactattga ctgccctatt
    10021 ggcgcttgca acatctggtc cagtcttatc cgatgccttc atatcggctg gcgctttctg
    10081 cttgacatta tcaatcttac tttgcgccga ctgagtatca cctgctgttt tatccgtagc
    10141 attcacatca gcaggtactg tttgtttaac gctatcaaga gcttgttgag cggacatagt
    10201 tggttcttgt gttaagtttt tcgctagtaa gactttttct tctggtgtca acacttgcca
    10261 ttgcgctaac aactctttgc tatcaaaaat ttcaatcatg gcctgttgcc catccacaac
    10321 caattttttc tgttctaacg tcatgttttg ccattggcca ccagctacta gcatttcagc
    10381 aagtgcggct ctccccgtcg gttcaacatc agcgttctta accatgattt caaagctatt
    10441 ccaaccttct gccgttgata acaattcgtt taaactttgt tgtggattat cactcgtaaa
    10501 caaactgtcc cattgagcat ttgctgctgc tacctctgca gtagcattag cggtattacg
    10561 tgataaaact ttcaacgttt caccggattt ttcggtatag taagccattt tgcgataagc
    10621 gtcatcatag ctaatgccaa gcttctgagc catatctgac gccatttgac ttatgccgcg
    10681 gtggatttcc tcttgacttt taccagattc ttttaaccgt tggactcgct ccctctggat
    10741 agcaagatac tgatcattca aagctttggt ttttaggttg tgctgcatat taagttcggt
    10801 aagtctattc aaaacttcct gtctagcagc caactcttca gcactcaatt tactagtgtc
    10861 gctgccaaat tgcttcaaaa tctcttttaa ctctgctttt tttgttttat atgcagaatt
    10921 ttctttatcg agcatcttaa cagtgttttc agatactttt tccaactgcc ttgcatttag
    10981 cgcatctaac tcgttattca aagctgctgt taaagctttc ttttctgatg cagaaaactt
    11041 cattaaatca agttgagcaa taatcatttc tctctgattt cgcaaaacaa gttctttttc
    11101 agcgcttgac aactggctca tgtcaccatt gtgcttctcc atgattgctt taatctgggt
    11161 gttcatgctt ttaacattgt taactactga ttcagttttg gatttcaaag catttatggt
    11221 ttcttctgac aatcctaatt ttttagctaa gtttatattc ttatctaatt ttgattgagc
    11281 taacttttca atacttccga ccaaatcatc aaaagcttca gtcactttct taacgctacc
    11341 tgcgcctgcc tcgaacattt gcaaagaagt gttagtttcg tcaacttttt tcttaaagtt
    11401 acttagtgca gttgcttctg tcgcggaaac agcggttccc cactcttccg tgcgtttttg
    11461 ggctttatac atgctatcag caattaaacc aataccaata acagctgcgc cacctagcaa
    11521 aacaccccac gttaccgggt tgcttaataa ggcaaccgcg ccagtcaaac tgcccataga
    11581 agctgtggca gcttcagctc caacacttgc tgctactgca ccggctttaa acgtgcgtag
    11641 ccaaccagat aaagcaccaa tccctttgct catcttgccg atagcttgaa tggttccgcc
    11701 gataacacca atacccttac ccaaaataga taaagccggc ccagcggcgg ctgcaataag
    11761 tccccacttg ataatttgct gttgttgctc tttgtcgagc gagttaaatt gtttagctaa
    11821 gtcagccgcc atttggatga ttggcttccc tgcttcgagc ccgtttctca gagcgtcaac
    11881 caaaggacca ccaaattcta tggctacatc attgacttcg tttttaagca ttttcagctt
    11941 agactctgtt gtctcgtaac gtttgttagc ttcgtcagtc aacgccgtgt tttctttcca
    12001 agccttattg gaaattccaa gtgccttgcc taatgtttca gatgctaaac ctaatgattt
    12061 caacatgtta gactggcgaa taccgcttaa tcctaactca tcaagtactt ttgtggcact
    12121 ttcgcctttt ttatcaagtt gaccaagccc cttaataaac tcttgcaatg cgacaattgg
    12181 cttttctttc cacgctctag caaaatcggc tgaggacatg ttagctatct gagcaaattt
    12241 atttaaatta tcgcctccag atgcgactgc acgttcaata gctgataatg attgagtcat
    12301 tgctgtacca ccagcctccg cctctatacc aacgcttgac attgctgtag ctaaagctaa
    12361 catctcctga ttagttaatc ccgcaagctt accagatgct gctatacgat tggtcattgc
    12421 aacaatgtct ctttcagttg tcgcaaagtt attccctaac gcaacgacag cacttccaaa
    12481 acgcgaatac tcagatgatg ctagacctgt aatatttgca attttagcaa tagacgtcgc
    12541 cgcttcctct gcagataaat tggtagattc tcctaaatca atcattgtac gagagaaact
    12601 aagaatatct cctgtcttaa ctcctaattg acctgctgct tctgcaacgt gagcgatttc
    12661 aacagcactg gctggcaact ctttggccat ttgtctaatg ccttgcgaca acttagcata
    12721 ggataccgtc gccgtttcat ccacggtttt cttgacaccg gcaaaagcag attcataatc
    12781 gacagccgct ttaatagcat aaccagctcc tgcaacaatc ggagctgtaa ctcctcttgt
    12841 aaatgcagca cctacaccgg cgacagaatc gccgaatgac ttcatcttcc cgccaattct
    12901 ttcagcagct ttaccaaatc ttgtaaagac gctagtttca gtggctaaag ctcgtaatct
    12961 gttttgcaat tccgccactt gcgctgctgt ttctagcatg gctgatttag cgccaattaa
    13021 tttttgtttt tgctcagcag tagcgttatt aacatcacct atctcttttt ttaggtcgct
    13081 atatttttgt gactgagttt ttagtaattc ttggtaacct tttaatgcac tacctgtttc
    13141 agcatagacc gctttaagac ctttaatccg cccgccatgc ccttgaaagc tcttttcaac
    13201 tgcttttaaa gagttatcta agcctttcat gtaggttttt aggtttcttg tgtttgacat
    13261 aaagggtgat atgtctaatg tagctgttgc tactaaatca cctatattcc ccatttagtc
    13321 tcctttctag ccgaaaagga atgggaatgc cttatccaag gtcgtttcaa tcacttcttc
    13381 tttttcgaca gtttcaattt ctagtgcttg taccatcaat tcgatgtctg ataagcgcat
    13441 ttttttaata tctaaaatgg tataaccgtt tttcaaaagg ctctgtatcc acaagagtaa
    13501 gttttcttta gcctcttgtg gggttattgt tccttttttt cgctttcgtc ttcctcctgc
    13561 tctcctccga gtgctgcaat gtacaggtca ttaagtgtat ttaaaacggt catatcagat
    13621 tgctttaaat catcaacggt aaactgacct gcgtacatat caacaaacat ttgcaagtaa
    13681 gattcgttaa gttttctatg cgctttagaa tctaaacgtc ttttctcatc gctaaacaca
    13741 gcgctttgtc taacttgatg ctcaacagcc aacaaattat cttcgacatt gataaagtct
    13801 tttttaaatt ccttatcaac accgcctttt tttaaggtaa tttcgtacat atctactcct
    13861 tgtcaaaaat aaaaggtcgc agcttaaatg cgaccttaaa aattacataa ccgtacttgc
    13921 ttgttccgca attggtattt ttttaatttc tgcatcaccg cagccggcaa atacacattt
    13981 taaaaattca ttcaaattaa aaccgctatt accctcgcgc ccgaccaaaa gcacttcctc
    14041 ttttggtccg cgggcaacaa agttacccgt tgtagtatct ggtttcggat caggtgcgcc
    14101 ttcttttgtt tgtgcctcca ttcccggaag attaaatttc cctttaagca acgcaatcca
    14161 aatcgcctta ccgttttcat cgctagtcct aaataaacaa acaatgtcat ttggcgttag
    14221 gtttttgttg tacttctcaa cacctttttc tactgtgatt ccaaagaaat ctttgcgtgc
    14281 atctgatgtt aaatctaaca actcgatttc aagttttgtc tcgctgattc cacctgataa
    14341 tacaacgtaa ggtccatcgt ctgctggcac agtgaccaat tcattggtaa tatcaagttt
    14401 tgcggatttc attcccggca aatgctttat actctctgct tttgtaacct tgtcatttcc
    14461 gtctagtact ccatagtaaa aatcacgtag tccaaatttt acttttccca ttttttcctc
    14521 tttcttttaa taaaaatcaa aatagcggta tttccttaca ttcatgagta agtcaatatc
    14581 tctatcttta tatcttggtt tttcattcgc ggtatatctt tcaaaaccgc cttgttttaa
    14641 aatgttatct atacatttgt taatttggtc agcttctgaa gctgttttgc accaaaaatt
    14701 aatagttata cgttgctcat tgcaaagtat ctcgtcatca gcataatcaa aaggaccatc
    14761 taacgttgtg ttaattcgca taaatggtgc caattctact tttcgtaagt taacaggatt
    14821 atccgggata tcataagtaa aaatcccttg tttaaatcca tttttaaaag taccgcctct
    14881 gagcctatcc aacagctcat ttagcgtctt atcgttactt aacaatttat aagctgctgt
    14941 ttcagcaatc aaagtcctag tccctcctta actttttcag cataaatttg tctggctctc
    15001 ggtgtcatct gattgattgt tctttccttg aaatcctgtc cacgttgata aattgtccca
    15061 tcgttaggat agtgagcacg ccaacctgtc gctttaccat aaccgatttc ttttgaaaca
    15121 atgccgacat tagaaccttt gaaaccgctg ataactgtat cttcttgtag ccgctcatct
    15181 gtttcaatct cataaacagg tgtatttgat ttgagggtct tctcaaattc tttcgcaacc
    15241 ttagtcacgg cagcttttgc agtttttgaa gcttttactt caagctttgt cagattagcc
    15301 aatatttcat ctaaaccctt tgtcatgaca tgcttactcc acttatcatg atcatatctt
    15361 tgccggattc gtcagattcg attttatcta tcttataaat gcgcttgtca aactcaacaa
    15421 acatcgtgtt atctatggat aattcagggt tatacctaat taaaaaaact tttgtatcct
    15481 tatttgtcgg cagattgcta gcgttttgaa actttgattg gtaattaaag tctcttaact
    15541 gcgttttcaa tacttctgcc caacaggtat ataagtcttt tctgatagca gatactactt
    15601 caccatcttc attttgccca cctgattggc taaaaatcgt tatcctgacg ttcatcttgc
    15661 gtgtaatcat gaatcatcac cccgcaatcg tagttgatgg atgatattta aaacgccatt
    15721 tgccaacgga tagcgaaaac tatccgcaga caaaccgcga tggtcatact cttccttgac
    15781 ttgttttttg actgctaaag caaatttagc gctttcctta aacgtgcctg cggttgagcc
    15841 ctcttctatc gcaaaacaaa tttgttcctg agcagattca atcatttctt taatgatgtc
    15901 atcctcaaaa tcaaagtcaa ttttacaata gagctttaca ctgtctaata actctttcga
    15961 tacagccatg gctatacctc ttcaacgcct gctagtgcaa gtaaatctga tttcaatgtc
    16021 ttaccactaa agtcaattcc cttgcttgtt aaatagcgtt tgatttcttc tacagtgctt
    16081 ttgcttgttg gtttcgccac ttcttcagtg gccttacgag ggcaattgtt ctggcgtaaa
    16141 tgtcacatag tagccagctt tgtcatctac cttagcaaca ccgaaacgta acacagcttg
    16201 caaatattga ccgtaaatgt cattatcgac ccaacgcaaa cctaagtctt tgcggtcggc
    16261 gaataacaca ccacgtttga aatctccgac aaatgcttta tttttaccta aaacctcatc
    16321 ggctagtaca aaaacaggtt ttccaaggaa tactttccca gtaacagaag tgattgagtc
    16381 ttggagtaga taacgaccgt tttcgtcttt taaagtatcc atggactggt aaaagctttg
    16441 agatacgata aatgacacat tgtaagctgg atctaaatct acatttagga tttttttgat
    16501 ttcatctaat gttttgacat cagctttagg ctcaaatgtt tttaggactt tagcaattgc
    16561 atcattagtt gtattaactt tcatttgacc gattgtttca gcaacaattc caactaaatc
    16621 aacatctgca tcgtcaattg actcttgaga taatgggatg gctccacgat aagtctcgac
    16681 tttccactct acgtctttaa attttggttt agcaagcttt ggattttttt cgagctcttc
    16741 aacgctaacc attttttcag tcgcacattg caatactggc catttccctg acgctttttt
    16801 agctgggtgg atgctagtga attgtttcaa atcaacaact gtcttaactt cacgagctgg
    16861 tgtgtaaaga atttcttcac tagagacagg ttttacatct gttttcttaa caccgtccgt
    16921 tttaggatct ataggagtcg tttggttaag tgggataaga acctcgtctt tcccttcgaa
    16981 acgcaaagct tcgttagtta ctgttccttt tgaacgaata aattcgttaa cgctttcgcg
    17041 gtatgtttta gtttcttgtg gcacttcttt tcctccagta ttttctgcac cgcctttttc
    17101 aatgctagct tcatataact tcaagtcgtt ttctgcttct actaggtccg cttttgcttg
    17161 ttcaacttct gctttaattg agcgagcagt ttcaaggtca tctgattcca aagcattttt
    17221 tacttcggct gttttagtag caatcgcttg gtttaaacta gcgatagtcg ctttaatttc
    17281 tttgattttt tcttcgaaca taaattcctc caataaaaaa agagcttata gcccttgtaa
    17341 aatttcttct ttttcaattt ctagcaacat gttgctaatc tcttgcttgc gcttacttct
    17401 gtttgcgtaa tagtcgtcaa taacagcttg tggcaacatt tggttatcga tactcgccac
    17461 cgcttcaaaa gacatcactt catcagcaaa acctttttca acagcgtctt gagcagacat
    17521 aaacgtttca ttccgcatta aattcatgat ttcatcttcc gataaccctg tctttgcgac
    17581 ataggcattc acgatagctt tatcacttga tttcaaagca ttagaagcct tatctaagtc
    17641 atcgctatta ccagctaccc aattaaacaa tgccttgtgt accatcatct gtgctgttgg
    17701 actcatgaca actttatctg ctcccataac tgcaacggat gctgcacttg cagccatgcc
    17761 agtaatttct gcagttactt ttcctttgta atttcgcaaa gcggtataga cttcactccc
    17821 tactgtaaca agaccaccgt ttgaattaac ttccaaaata atatcactgc tatcttctgg
    17881 caattggtta ataatgcttt tggcactagt cgcttccatt ccatagtagt cataaacttc
    17941 ttgcgaatta tttgcaataa gtgggccttt aagatttatc ctctttggca tttacctcac
    18001 ctcctttccc tttgatacca accttgtcct gatattcttc ttttttatcc aaaaagacat
    18061 agtttagact cgattggtac ctatccatat taggatctgt agatttctgc ttacctaact
    18121 caataaggcc ttggttaggt gtcagtattt gattgttaac caatttgaca atctcatcaa
    18181 cattacggcc tgtaacgcta cgtgtatcaa attcaatacg atagagacgt ctatctttat
    18241 catttaacgt tttaagacct aattcgcttg taatcgcgtc aaaataaaaa ggcaagtcgt
    18301 ttgtgacata gtcctccatc agttgagcta cggattgatt agggctatta acaccaagct
    18361 tgtagctggg aacccgcaaa gcttttgcga tttgcgccgt tgaaaaattg ttactagtga
    18421 ttaactgcaa tacgttagta tcaatttcaa gcggcgtgta ttccatggta ctatcaaaca
    18481 ccaatggact gccaccgatc gaaccctcgc gcattttctc aaactcttga cgtgctcgct
    18541 gccgtgcgtc tccgcttaat tgagcacctt tcatagttaa gataccgcta gaaaatccat
    18601 ctttaaagaa tttaattaag gtattgatac cacctgtttg caaatcaatc tcatctccta
    18661 aagacaatag cggagacctg ccaaggattg tgtcgtggct aaaaaacttc cagtgtacaa
    18721 catcatgagc aaagcattta acctgttttg ctgttaacgt atcagtaaaa gtgtagatga
    18781 tttcgtgact atccgtttcc tctactgttg tttctgatgg cctgtaaaat tggaattgca
    18841 aagcttgatt agtctttgga tctctcaaaa tacgcgaaaa agaattacca gtcaaaatgg
    18901 catttactgc catagcaaat ttccatgtcc tggcgctcgc attttttgta gatttaacat
    18961 ttaaaagata attaatatcc tcatcatgga taatgtcccc attaacatcc tttttaacaa
    19021 gcgggaacct agcaatatcc ccagctataa tagacgttgc tgttaaaata tcgctattct
    19081 tcaaagccga cacccctaag tatttttgag agacatcacc agctaaaaca gatgatatat
    19141 agtcatcgta ggacaccttt gaactgccca aaggtcggaa aaaactcatc gatttctcac
    19201 ctcctttcta aaccattaac atctatttcc gccacttgcg cttataattt tgcttgatgt
    19261 gaccaacctc atcaccaatt gacttgatag ctacttgatt gtctagtatc gctgatttaa
    19321 ctgctgcaag ctcgttattt gtagctttgg catttgctga cacgatggat cgtaattcgg
    19381 cgacttcttt aattagcaac acaatagctg tttccaattt tcgttttttc ttaatgcgtt
    19441 tattcacgtt ttcctcctac gctatctaca tagatagcta aaacaattaa aataagacca
    19501 ctggcaataa aaccgacttt atcaccaaac aaaaacaacc catacatcaa taaacctagt
    19561 ccagctaaca agattaatgt gtgtatgttt tttaaaataa aatcaatcaa aacagcgatt
    19621 ctcctcctat tattttttca tttgtccagt agccagaacc atcgaacggt tctaagtaac
    19681 aaacagcgta gccatcaaga gcagcatcaa gcgggtcaat cttattgcta ttcttattct
    19741 tatcgatcct cataccatta ttatcagttt taatataagc attgttaata gccatggtta
    19801 gcaaagggtt accagagtgc tttattttgc cttttttgag gtcgtcacga aattgttttg
    19861 tcggcatgtt caaaaccatt gtcgtttgac taacctcaat cagaggccac tctggatgcc
    19921 ttttttcaat cattgtaagt aatgttccaa attgataagg gtcaaaacaa attccattaa
    19981 tttcccagtc gtttgagtag accatctctt caattttttc gagtacacgt tcatcatcga
    20041 tgacaccact ttctagggtg gttatctcgc aataaccttg gcattcaagg ttgctataag
    20101 atacgccatc ccgcttttct ttagcagtta aaccatattt ggtagccaca aaagaaaagc
    20161 tgtcgatata ccaaaaatca tccatcataa caactggtgt gatagcaaat aagtcgctaa
    20221 cacgaccaac gtcaacacct aaccaaactc tccgcttatt agtatctggc ttatcaatcc
    20281 gagcaagttc ccaagtcgtt ttatcgatgt aagattcctc actagactga cgccacatgt
    20341 taaagttttt gattaatact ttattgattt caccagtttc aagggacact ctacgacgcg
    20401 ttctcaggta atccattagc ttatcatgta aagcttcaac ctcaaggatt ggatttgatt
    20461 ttatccagtt tgattcgtct ttaatttcct cttcgttgtc ctgttctgca acatatccaa
    20521 aataaccctc gtctgtgatt tctccgtcta gtattttagt gatgtatgga tactcaattg
    20581 tgtgcatagg gacattcaaa tccatccctg ccgtcgaaat aatcaagata aacgggttat
    20641 caagctgacc ttgaccagat tctaaaagtt ctaacatttc attcgtcttc gatgctgcaa
    20701 attcatccaa aacgccaaca taaggctcaa atccatctac agccccagta tctcgactaa
    20761 gtgctctgat atatgattcg tcatgtaagt ttttaagctc atcacggaca atttttgtag
    20821 cctttctgac atcagcgtcc ttcgctctga gagatgataa ctgcttcttt gccatatccc
    20881 aagcgatttt agcctgcgtt ctatcatttg cagtacaaaa caattgtctg ctcatagatg
    20941 ggttatggcc aaacaaaaat tcgtaaagca agataccagc tatcagaatt gttttaccgt
    21001 ttttacgagc aacagaaatc atagcttttc taaaacgtct caaggaatga tctgttttct
    21061 ttcgccatcc atataaattc ccaataataa acttctggaa catcgccaac gggtaaggtt
    21121 tccccgtttt tacatctggc aaaatctcaa taaagttaat cggatcagct gctttttctg
    21181 gtaaatagat gaatttaaaa ttatcaccat ctattttttt gaggtcattc aaatgtctta
    21241 aacaagctct aaataccttc ttacttgatt ttatctgttc gtcaacgacc atttttgcat
    21301 aataaaaagc gtcatcttta tagatgtcgc tgattgctga ataatcgtat tccactttta
    21361 tcacctacaa acctatacgg aatgattggc ctatcgtttg catataatac cgaccacctt
    21421 cttcgctaat atactccact aaaaaaccat tatccaacgg attgttttgg gcgtcatctg
    21481 aatcatactt aacaattaat ttagtgatac catttatttt ctcaccgttg atttcaacaa
    21541 ttggaaactt accattttct aatagcttaa cagaaaattc tttaactcgt tccattttta
    21601 tcctccaaat ttatcaaaaa tactcttagg cttttcctct tctttaggaa taaacatttt
    21661 catccgacta tccacagtca acccaagctg acttgcgcta cttctaatat tcgctgtggc
    21721 tttttctagt gttaaaataa gcggactagg aataatgccc ttgtctggat cattcgtaaa
    21781 ataaccaacc tcatctagtt ttctacttgt ttctttgtag atagcatacc atgtgcaata
    21841 taactctaat agccctctat cgagatttct taggggtagg ttttggaggt cttctatgat
    21901 tctcctatac tcgtacttag ctacattatt aaagtgttca ggaggtgtct tttgcaactt
    21961 tttaagaccg tcagacgcct tattttgcgc ggtttctcgc actatttttt cttctttcgt
    22021 aagatgcttt tttgtcgttt cgactagctt taaatttctt cccataagac ctcctttaca
    22081 cgaactttac agttttaaaa atttcaaaaa gggaattttt tgcacggaaa agggcgcgtt
    22141 cttaagtttc cgaacaatat agccccgttt aaaaatgaag ggggtagttt ccgaatatta
    22201 acatactgtt gttaattttt acacccgttt ttacattaat tgtttttacg tctttctcgt
    22261 atcgctttac tatcattaca tgctttacag cttgcttgca agttattcca atctaatctt
    22321 ttgttccaat cttgtttgac tgatacaatg tggtcagtca tagtcgcttc gccaccacac
    22381 atagcacaga tgtaatcgtt ctgaagtaat acttgcttac ttgtctctct ccatatcctt
    22441 gagttataaa actgtttggc ttgtttatcg tacttccagc gattacgatt atagtcacga
    22501 tactctgctg atctatcatc gtagtcaact gttgtacgtc taccacctgc gatggttaac
    22561 ttctgtggcc tcataccctg acctcaccag ttagcctatt aatataatga actaatgttg
    22621 tgtatggaat agtgtagccg ttatcaacgt atatattact tacttctttt tcccattgtg
    22681 gtttactata cggatactta tttggtctca tttgttatct cctaattttt gcgtatttta
    22741 tgcgtatttt gcattgacat ctacattgtt tatgtgtata atataagtat agaaagtgag
    22801 gtaagcaata tgccaatgac cccaaagcag atgataaaac tgctaaaaaa gaatgggttc
    22861 tacgaagtca gtcaaaacgg aagtcacaaa aaattccgag acaataacgg acatcaaacc
    22921 attgttccaa tgcacaataa agacctcgga aaaggtcttg aagataccat tctaaagcag
    22981 gcgggtttaa aataatccgc ttgccagatg gtgtgcttat ctcacagtaa tcaaaggagg
    23041 atcattatgt taatttatcc agctacattt acacaagaca cagactatat catggttaca
    23101 tttccagatg tacctgaagc aattactcaa ggtgaagact ttcaagaggc ttatgaaatg
    23161 gctgtcgaag tcttaggttt tgcccttgaa gactatactg actatccaaa ggctagcgcc
    23221 gtttctgatt taaaagaaca gtatcctgat tccgacattg ctttaattgg catcgatatg
    23281 gttgcctata tgaaaaaata tcactccaaa aaagtccgca aaaacgtgac tatccctgaa
    23341 tggttaaacg acgcagcaga agataaaaac ctcaactttt ctcaagttct tactgaagcg
    23401 cttgaattaa aattacaagc ataagagcca ctgttgtggt tcttttttac ataataaaaa
    23461 accacgacgt tgacctatcg aaacattgta atttcaacgt ttgtaactaa taagtaacca
    23521 tgtcgcggac cataacaaaa aaaatcacca ctatgtgatg actgccataa acagtttttc
    23581 agttctctta cccgctccgc caccttgcat ggtgcttctt gcagtcttaa actcatatac
    23641 gcattcaaaa cgttcatctg atatatcgta actagaaatt aaaacaatgt tgtttttaga
    23701 catcccaaac gcccaatcat aaaatgcttg actgttaaaa tcacctttat aacttttttg
    23761 cgtggtattt tcgtatggag gatcaagata aaaaatagcg tcttcaatat ctgaaaatgc
    23821 ttcgtaacta taatttgttg gttctaactg ttctaaccgt cctaactgtt gtaaccgtcc
    23881 taactgttgt aactgttcta actgtgttag ttttttattt ttttcaagct ctccttcatc
    23941 gtaaggcttg tcagcttttt tatacgtttc ggtttgtttg tacccgctaa acacatcgtg
    24001 cttattaatt atttcaaccg ctaagtcata cttcgtatca gaccagtctg cgccgtataa
    24061 ataactgctt aattcattcc caaaactatt tactaacaat tttaaattat catcaactga
    24121 cttaggttct ttttgcctaa ttttgttaaa ttcatcacga ctgataatga gtgtttttat
    24181 ccattctcta tcttgactaa tcacacgctg aaacatatct gttatatcgt tgtctaagtc
    24241 gttataatgc acttctaaac catttagcac acactcagca gtaatcgctc cgcctccgcc
    24301 gaaaacgtcg tatatgggtt tatctgcatc aaagttttgt ttaataattt cgactatttt
    24361 cttactaatt ttctttttac taccttgata cggaagtcca actggtttcc cttttcgtat
    24421 tttcttttcg tctaatttaa gcattttcac cccacaataa aaagccacca caatgtgatg
    24481 actaattggt taaccataga taaatagcaa atgaattcta agcctattgc ctaccccatt
    24541 ctgggacact tctatttatc aaacaggaac agtcggaatc gaaccgactt acaaccgttg
    24601 tccctactaa ccacaagcaa ggttgcgacc cttgttttac ttgtggttaa tcaaatgagt
    24661 caatctgttg tgaatacgta cacgtagact atacagccga tctatgtatc ttttttacca
    24721 atcgtcattg gtaggaatat gactatcaac caagtaaaaa ccagtatatc agtgcgtgac
    24781 tgcctttcgg gatactgggt cgcgcctctt ctgggcgctg attgagacgg caggaatcga
    24841 acctgcatac ccagttgtcg tctcaactcg ctgtaccgcc atcaggctac aaaataacaa
    24901 gtttgattgt agttaaagtt ggcgactaaa taaatagtca gttggtaaaa tggttatctc
    24961 ttcttgttat tttgctatgc tactatatta acactgtaat tagtattatg tagtatcaat
    25021 ttgtatctaa ttagtatttt ttagtatcaa ttccagactt tcctttccac gcctaacaaa
    25081 cataaagtat ttattacgat ttcctatgtt taagcgttct ctggctcttt catagtctcc
    25141 atcacagtca agataagtcg tgagtaaaac gtgactctca caaatgccca tgctttgcac
    25201 aatcaaatta gccatttctt gtcgacggtc ttttagttgc tcaatctgat cgctataata
    25261 gccgaccatg tgtaacattt ttatgttttt gtcttcctgt gattgtttaa ccccgccaga
    25321 taccttcata tcagaccact gaggagactt aacgagcgac cgactcatta ggttagcgtc
    25381 tctttcaagg gtctctatga gatgtgggat agtctttaat tcttccaaaa aattattagc
    25441 ttttgttgtc ggaatgttgc ccatctaact ctccattcat gatataatat tgttgggtat
    25501 ttaatcatga aggcgttcgc atggacgtct ttttttgtgg agaaaagtcc tctctttcct
    25561 ttgttttttg acacaggcgc acgatgtcgt gttaaagcat tagcgacgcc
//
LOCUS       DAUGUF010000026        25422 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUGUF010000026 DAUGUF010000000
VERSION     DAUGUF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25422
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.026"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(525..911)
                     /gene="rplQ"
                     /locus_tag="VIB71_001178"
     CDS             complement(525..911)
                     /gene="rplQ"
                     /locus_tag="VIB71_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEQ8822913.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(926..1864)
                     /locus_tag="VIB71_001179"
     CDS             complement(926..1864)
                     /locus_tag="VIB71_001179"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEQ8822914.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1910..2293)
                     /gene="rpsK"
                     /locus_tag="VIB71_001180"
     CDS             complement(1910..2293)
                     /gene="rpsK"
                     /locus_tag="VIB71_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEQ8822915.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2311..2676)
                     /gene="rpsM"
                     /locus_tag="VIB71_001181"
     CDS             complement(2311..2676)
                     /gene="rpsM"
                     /locus_tag="VIB71_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEQ8822916.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2694..2810)
                     /gene="rpmJ"
                     /locus_tag="VIB71_001182"
     CDS             complement(2694..2810)
                     /gene="rpmJ"
                     /locus_tag="VIB71_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEQ8822917.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2836..3054)
                     /gene="infA"
                     /locus_tag="VIB71_001183"
     CDS             complement(2836..3054)
                     /gene="infA"
                     /locus_tag="VIB71_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEQ8822918.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3172..3810)
                     /locus_tag="VIB71_001184"
     CDS             complement(3172..3810)
                     /locus_tag="VIB71_001184"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEQ8822919.1"
                     /translation="MNLLIIGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3960..5264)
                     /gene="secY"
                     /locus_tag="VIB71_001185"
     CDS             complement(3960..5264)
                     /gene="secY"
                     /locus_tag="VIB71_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEQ8822920.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5281..5721)
                     /gene="rplO"
                     /locus_tag="VIB71_001186"
     CDS             complement(5281..5721)
                     /gene="rplO"
                     /locus_tag="VIB71_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEQ8822921.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5936..6118)
                     /gene="rpmD"
                     /locus_tag="VIB71_001187"
     CDS             complement(5936..6118)
                     /gene="rpmD"
                     /locus_tag="VIB71_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEQ8822922.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6133..6627)
                     /gene="rpsE"
                     /locus_tag="VIB71_001188"
     CDS             complement(6133..6627)
                     /gene="rpsE"
                     /locus_tag="VIB71_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEQ8822923.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6646..7002)
                     /gene="rplR"
                     /locus_tag="VIB71_001189"
     CDS             complement(6646..7002)
                     /gene="rplR"
                     /locus_tag="VIB71_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEQ8822924.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7107..7643)
                     /gene="rplF"
                     /locus_tag="VIB71_001190"
     CDS             complement(7107..7643)
                     /gene="rplF"
                     /locus_tag="VIB71_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEQ8822925.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7846..8244)
                     /gene="rpsH"
                     /locus_tag="VIB71_001191"
     CDS             complement(7846..8244)
                     /gene="rpsH"
                     /locus_tag="VIB71_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEQ8822926.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8395..8580)
                     /locus_tag="VIB71_001192"
     CDS             complement(8395..8580)
                     /locus_tag="VIB71_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEQ8822927.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8596..9138)
                     /gene="rplE"
                     /locus_tag="VIB71_001193"
     CDS             complement(8596..9138)
                     /gene="rplE"
                     /locus_tag="VIB71_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEQ8822928.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9162..9467)
                     /gene="rplX"
                     /locus_tag="VIB71_001194"
     CDS             complement(9162..9467)
                     /gene="rplX"
                     /locus_tag="VIB71_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEQ8822929.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9546..9914)
                     /gene="rplN"
                     /locus_tag="VIB71_001195"
     CDS             complement(9546..9914)
                     /gene="rplN"
                     /locus_tag="VIB71_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEQ8822930.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9939..10199)
                     /gene="rpsQ"
                     /locus_tag="VIB71_001196"
     CDS             complement(9939..10199)
                     /gene="rpsQ"
                     /locus_tag="VIB71_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEQ8822931.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10225..10431)
                     /locus_tag="VIB71_001197"
     CDS             complement(10225..10431)
                     /locus_tag="VIB71_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEQ8822932.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10441..10854)
                     /gene="rplP"
                     /locus_tag="VIB71_001198"
     CDS             complement(10441..10854)
                     /gene="rplP"
                     /locus_tag="VIB71_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEQ8822933.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10858..11511)
                     /gene="rpsC"
                     /locus_tag="VIB71_001199"
     CDS             complement(10858..11511)
                     /gene="rpsC"
                     /locus_tag="VIB71_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEQ8822934.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11524..11868)
                     /gene="rplV"
                     /locus_tag="VIB71_001200"
     CDS             complement(11524..11868)
                     /gene="rplV"
                     /locus_tag="VIB71_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEQ8822935.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11884..12162)
                     /gene="rpsS"
                     /locus_tag="VIB71_001201"
     CDS             complement(11884..12162)
                     /gene="rpsS"
                     /locus_tag="VIB71_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEQ8822936.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VIB71_001202"
     CDS             complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VIB71_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEQ8822937.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13153..13449)
                     /locus_tag="VIB71_001203"
     CDS             complement(13153..13449)
                     /locus_tag="VIB71_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEQ8822938.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VIB71_001204"
     CDS             complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VIB71_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEQ8822939.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VIB71_001205"
     CDS             complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VIB71_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEQ8822940.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VIB71_001206"
     CDS             complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VIB71_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEQ8822941.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGAKVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15477..16766)
                     /locus_tag="VIB71_001207"
     CDS             complement(15477..16766)
                     /locus_tag="VIB71_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEQ8822942.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VIB71_001208"
     CDS             complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VIB71_001208"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEQ8822943.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNVGHGKALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPIVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VIB71_001209"
                     /gene_synonym="adhC"
     CDS             complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VIB71_001209"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEQ8822944.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALAEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21374..23149)
                     /locus_tag="VIB71_001210"
     CDS             complement(21374..23149)
                     /locus_tag="VIB71_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEQ8822945.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLFWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMVGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGTLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPNGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23146..23547)
                     /locus_tag="VIB71_001211"
     CDS             complement(23146..23547)
                     /locus_tag="VIB71_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822946.1"
                     /translation="MINMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23571..24008)
                     /locus_tag="VIB71_001212"
     CDS             complement(23571..24008)
                     /locus_tag="VIB71_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEQ8822947.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     KPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMNKEY"
     gene            complement(24146..25144)
                     /gene="ruvB"
                     /locus_tag="VIB71_001213"
     CDS             complement(24146..25144)
                     /gene="ruvB"
                     /locus_tag="VIB71_001213"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEQ8822948.1"
                     /translation="MARILDNDVMGNEEFSDRTLRPQYLREYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25191..25286)
                     /locus_tag="VIB71_001214"
     CDS             complement(25191..25286)
                     /locus_tag="VIB71_001214"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEQ8822949.1"
                     /translation="MLKKYKYYFIFAALLSFKVVQELSAVDWWRL"
BASE COUNT         7522 a         5345 c         4459 g         8096 t
ORIGIN      
        1 aattttgttg gaaacggctt aaagtgacag attgtaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt aaaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttgcgat gcaagttttt ttcggacatt taaacgaggg
      181 gattacaccg tttatttgcc catgagaggt ctttaaacac ctgcataagg ttttcttatt
      241 ctgatgacct tattgtctct gagaaaactt tataaacgca tcagaagagg cttctgtgtt
      301 attgttttac tcagcttaaa agcgggagtg tcacctcata atacaacaaa acgcctgctt
      361 ataaaaagtt tctatagctt agataccttt cataaacaag cgtcacatat taacaatatg
      421 atgagtgttc ccgctaggaa aaatcctagc ggtagaccag agctagacta agaataatct
      481 ctcgattact ccatcatcat aacactcaac aaaattgata aaaattaaac taattcaata
      541 attgccattg gagcagcatc tccacggcgt ggttctgttt taagaatacg agtgtatcca
      601 ccgttacgtt ctgcataacg aggtgcaatt tctgagaaaa gtttttgaag agctgtcgtt
      661 gatgtgtatt tatcggtagc ttcatcataa ttttctgatg cgatttcgtt acgaacgtat
      721 gcagctgctt ggcgacgagc atgaagatca ccacgtttac caagagtaat cattttttca
      781 actgttttac ggatttcttt tgcacgtgct tctgtcgtta caattgattc gttgatcaaa
      841 agatctgtcg tcaaatcacg aagcattgct ttacgttgtg agctagtgcg tcctagttta
      901 cggtaagcca ttttgtcctc ctatattatt tatcgttttt tagtccgaga cctaagtcag
      961 caagtttaac cttaacttct tcaaggctct tacgtccaag attacggact ttcatcattt
     1021 caggctcaga tttttctgtt aagtcgaaga cagtgttaat gcctgcacgt tttaaacagt
     1081 tatatgagcg tacggataaa tcaagctcct cgatggtgcg gtcaagtacc ttttcatcgt
     1141 tcactttttc agtttctttc attacttcgg tagcttttgc aacctctgtt aaatcagtaa
     1201 acaggtttaa gtgttcgatc aaaactcgag cagatagacc taaagcatct tcaggaataa
     1261 ttgttccgtt tgtcatgatt tcaatcgtta atttatcaaa gccatcattg ctacctacac
     1321 gggcaggttc aacttgataa ttaacttttt taactggcgt atagattgaa tctactgcca
     1381 atgtacccac aggtgcatca tcttttttgt ttccttctgc tggcacataa ccacgttttt
     1441 tagcaacagt cattgttgca cgtagagaat gtccttcagc gattgtaaaa agataatgat
     1501 ccgggttaac aagttcgata tcactgtcag taagaatatc accagctgtt acctctgctg
     1561 gtccttctac ttcaagttcg ataatctttt cgtcttcgac gtatgatttc acagcaagtc
     1621 ccttaacatt aaggataatt tgcatgacat cttcacgtac acctgggatt gtatcaaatt
     1681 cgtgtagtac tccatcaatt ttaattgatg ttactgctgc acctggaagt gaagacaaga
     1741 gtacacgacg aagagaatta cctagagttg ttccgtagcc acgttcaagt ggttcgataa
     1801 caaatctacc gtaatcttta ttttcatcaa tttttgttat tattggtttt tcaaactcaa
     1861 tcattttttc acccctcgaa acgaaacttg tgtactattt gttatatgat tatacacgac
     1921 gacgttttgg aggacgagca ccattatgtg gcacaggggt cacatcacga attgcagtta
     1981 cttcaagacc tgcagctgct agagcacgaa tagctgattc acgacctgaa ccaggacctt
     2041 ttacagtcac ttcaacagtt tttagtccgt gttcttgtgc agattttgca gcagcttctg
     2101 cagccatttg agcagcaaat ggagtagatt tacgagaacc tttgaaacca agagcaccag
     2161 ctgatgacca tgcaagagca ttaccatgca catctgtaat cataacaata gtgttattaa
     2221 atgtagcgtg aatgtgtgca acaccagatt cgatgttctt tttcacacga cgtttacgtg
     2281 ttggtttagc caattgtttt acctcctatt ttattttttc ttacctgcaa tcgcaacagc
     2341 tttcccttta cgagtgcgag cattgttttt agtattttgt ccacggacag gaagtccacg
     2401 acgatgacgg attccacggt atgaaccgat ttccatcaaa cgtttaatgt tcatgtttac
     2461 ttcacgtcga aggtcacctt caactttgat tgcatccact tcacgacgga tagcatcttc
     2521 ttgatctgat gttaaatctt taacacggat atcttcagaa atacctgcag ctgctaagat
     2581 ttttttagat gttgcaagac caattccgta aacataagta agtgaaatta ctacgcgttt
     2641 atcatttgga atatcaactc cagcaatacg agccattttt tctcctttct attttatcct
     2701 tgacgttgtt tgtgttttgg atttgtcgga caaattacca taacacgacc attacggcga
     2761 ataactttac agtattcgca aattggttta accgatggtc ttaccttcat gttttaatcc
     2821 ctccaattat ttcgattatt taaagcggta tgtgatgcgt ccacgtgtca agtcataagg
     2881 actcatttct actgtaacac ggtcacctac taaaatacga atgtaatttt tgcggatttt
     2941 tcctgataca gttgctagaa tttgatgtcc attttccaat tcaacagtaa acattgcatt
     3001 tggcatcgtt tctactactt tgccttcaat ttcaatcacg tcttcttttg ccacgcaaaa
     3061 gtacccccta aatttcgatt tgatgtcctc tgagcacaga ggtaacaatt ataagtcaga
     3121 ctaaactagt atatcattac taatctactt atgcaagtag attagtataa tttatttgag
     3181 ttctagcaac gctttttcaa catctgcaaa aacgtctgtt atttcttgat taccttcaat
     3241 atctgtaaca agaccaagct tacgatagtg ttcaagaata ggttctcctt gagccatatt
     3301 gacgtccaaa cgacgtttaa cagtttcagg cttatcatct tcacgttgat agtaatcttc
     3361 ttctttataa tctactggtg ggttgaacac tttatggaac gtttcaccag ttttacgatt
     3421 gataatacga ccactcaaac gctctacaag acatgatgga tccactttaa tattaataac
     3481 accatctaag cggagtccta gttcttcaag tgttgcatct aaggcgtgtg cttgttcaat
     3541 agtacgtgga tacccatcaa gcaaaaaacc tttttctgcg atatcatcct cagctaagcg
     3601 ctcttttaca atcccgtttg tgacttcatc aggaaccaat tcacctttat caatataact
     3661 tttagctaaa cgtcccattt cggtttgatt agccattgcg gcgcggaaca tatcccctgt
     3721 tgagatgtga gcaacaccaa attcttcaac aatcttagct gcttgggtcc ctttaccagc
     3781 tcccggcaaa cctatgatta aaagattcat cttttcctcc tcttttaaaa taaatacata
     3841 gtaggaaatt attttccttg gtttttgttt tcaaatggca acaagaaatc gtttgatgat
     3901 aaccaagtct tattgtcatt taaaaacaaa atagaaggtt gacaatgtca acctgtattc
     3961 tattctgctg tattcataaa tccgacatat tttctcttta gaagatatcc ctcaagctgt
     4021 ttcatacctt cgataccagt tgaaatcaaa atgagcaaac tagttccacc taaagcaata
     4081 ctagaagaaa ggttgagagc ttgttgtgct gctattggcg ctaaagagat aaatgctaag
     4141 aagatagctc ctacggttgc tagttttttt agcaatgcgg acataaattg ttctgtctca
     4201 cgtccagggc gaacacttgg tatatatgag gaattcttct gaagattttc tgctgtcttc
     4261 tcaggattaa cttgtacaaa ggtatagaag aatgagaaca atataatcaa caaggcgtaa
     4321 actatcattc cgactggagt ttgataatta aaaatttctt gcaaacggtt taaccacggt
     4381 aaatctctac cattttgaac aaaaggaata atcgtacttg ggatagttgt aatcgagcta
     4441 gcaaagataa cgggaataac gccggctgga tttactttta atggaagata tgaacttgta
     4501 ggtgcacctt gcattagctt tgtgtattgg attggaattt tatattccgc ttgttggaca
     4561 tatgttgtaa agaaaacaat agcaagaaca gctatgatta aaatcccaac aatgagataa
     4621 gacgagtgta aatcacttgc cttaacattt acaaaatagt cttcacgaat tgttgcaatt
     4681 gcacttggaa tagacgaaat aatacccgca aagataatca ttgatacgcc attaccaaat
     4741 cctttatctg tgatttgttc tccaagccag gtaacaataa cgctacctgt tgtcagtaat
     4801 gccccgatca gtaaatatgt tttgatgtct ggtgtcttaa caagtgcaac gttcgacaaa
     4861 gtattaaacc ctgcagtgat accaatggat tgggcaaaag ccaaaacaag tgaaatatag
     4921 cgcgtcgctt gatttaattt acgacgtcca acctcacctt gtttgcccca ctcaacaaac
     4981 ttaggtaaaa tatccatctg caataactga acaacgatag aagcagtaat atatgggcta
     5041 acccccattg aaaatactga gaaatttctc atcgcattac cactaactaa gtttaacata
     5101 tttaagaaag ggagttcact taattgctct aagctcttgg catttacacc aggtacggta
     5161 atatgtgtcc caattcggaa tacaagaatg ataaatatag taaagaaaat tttattccgt
     5221 acagtcttta tctttaacgc gtcttttagt atttttaaga acataatgag tatcccctca
     5281 ttagatgact tcgattgaac cacctttagc aataatagct gcttcagcag attttgagaa
     5341 cttagctgct tttacagtca attttttagt caattcaccg ttaccaagca ctttaacgcc
     5401 tgatttttca gctcggacaa taccagcatc ttttaaaata gccggagtca cttctgtacc
     5461 atcatcaaaa acattcagtt gatcaagatt cacaagtgca tattctttag tattaatatt
     5521 tgtaaagcca cgttttggaa tacgacggaa caatggtgtt tgtccacctt caaaacctaa
     5581 acgtacaccg ccaccgctac gagctttttg acctttttga ccgcgaccag atgttttacc
     5641 attacctgat gatgtcccac gaccaacacg gttacgtact ttacgtgagc cttcagcagc
     5701 ttttaattca tgaagtttca ttttttctcc tttttttgta aaatgctagc gcctctatga
     5761 gggaaaagga ctccctatag aaactcgcct atacattaat gatacttaag ttatccaaaa
     5821 taacttaata cagatacgca ctaaccgact actgtttgtt gccaaaaaag caaactacaa
     5881 gagtcggttt tgtgctcgtt tttaattatg aaatcagaga tttcacagtt ataacttatt
     5941 taacatcttc aacggtaacc aagtgagaaa tagctgtcac cataccacgg atagcagcat
     6001 tatcttcttt gactactgaa gagtttaatt taccaagtcc aagagcaaca acagttttac
     6061 gttgttctgg cttacgtccg ataggagact tagtcaaagt aattttaatt tgagccatga
     6121 tgatcccctt tcttatgcta agtcagaaac tgagatgcca cgaagtgcgg caacttcttc
     6181 tgcacgttta agttgtttca atccttcaac agttgcacga acaatgttga ttggagtgtt
     6241 tgaaccaaga gattttgaag taatatcagc aacacctgct aattcgatga cggcacgaac
     6301 tgcaccacca gcagcaactc cagaaccttc tacagctggt ttcaataata ccttagctcc
     6361 accgaagtta gtgtaaactt cgtgagggat tgttgtacca accattggta cttcgatcat
     6421 gtttttctta gcagcttcaa ctgctttacg gatagcttct ggaacttctt gagctttacc
     6481 agtaccaaat ccaacacgac catttccatc accaacaact acaagagctg caaagcgaag
     6541 acgacgtcca cctttaacaa cttttgtaac gcggttaatc gcaacaacgc gttcttcaag
     6601 ttcaactgca ttatctttaa atgccattat tttgtgtcct ccctattaga atttcaatcc
     6661 gttttcacga gctgcatcag ccaaggcttt aacacgtccg tgatagagat atccaccgcg
     6721 gtcaaacacc acttcagaaa tacctttagc cactgcacgt tcagcaacaa gtttgccgac
     6781 tacaacggct tgttctgttt ttgttccttt agaaacgtct ttatcaagag ttgatgcact
     6841 tgcgagcgtt acacccgcta cgtcatcaat aacttgagcg tagatgcctg tattagaacg
     6901 gaatacgttc aaacgtgggc gatcagcagt tccagagagt ttaccgcgga cgcgacggtg
     6961 gcgtttttgg cggattttgt ttttatctgg tttcgaaatc acaattttca cctcttaatt
     7021 ttaatcaatt tgtctcattg acaagttgtc gattgaactt atcgagcatg ttaaggtgca
     7081 atacttccca tacccgacta agaacattat ttacctgttt taccttcttt aaggcgtacg
     7141 tattcaccaa cgtaacggat ccctttgcct ttgtaaggct ctggtgaacg caagctacgg
     7201 atgtaagcag ctgtttgacc aacaacttct ttgttgattc cttcaactga gattgaagtt
     7261 gggttagcaa cagtgaaagt aattccttct ggagcttcaa cttcgtcttg gtgagattta
     7321 cctactgaaa ggacaagttt agtaccttga agttgagcac ggtaaccgac acccttcatt
     7381 tcaagatctt ttttgaaacc ttcagaaaca cctacaacca tgttattcaa gttagcacgg
     7441 gttgtcccat ggattgtttt catttctttt gagtcgttag gacgtacaac tgtgatttca
     7501 gtcccttcaa ctttgatttc aatatttttg ttaaactcac gagtgagttc gcctttaggg
     7561 cctttaacag taataacatt gttgttattt gttaattcaa cgcctgcagg catagtaatt
     7621 actttattac caatacgtga catgtttatt ttctcctgtt aaattgtcaa gccgcatagc
     7681 gactagtttt cacgggggtt tgatagaatg atatacttca atttatattt caaaattgaa
     7741 cacgagctgt ggtctgtgtg aaaaagataa atcttccttg agtgtaaaca cgctacgtca
     7801 gatttcctat tttcactttg tccacgacgc tcttagtatc ttaaattacc aaacgtaagc
     7861 gatcacttct ccaccaacat tcttttggcg agcttctttg tcagtcaaaa gaccttctga
     7921 tgttgaaatg attgcaattc caagtccgtt aagaacttta ggcatgtcat cacgttttgc
     7981 gtaaacgcga agacctggtt ttgaaatacg ttttaagtta gtgataacac gctcaccatt
     8041 ttttccgtat tttaagaaca cacgaatgat gccttgttta tcatcttcga taacttcaac
     8101 attttttaca aaaccttcac gtttaagaat ctcagcaatc ccttttttaa tgtttgaagc
     8161 aggtacttct aacacttcgt gttttacttg attagcatta cggatacgtg ttaaaaagtc
     8221 tgcaattggg tcagtcataa ccatttttta tattctcctc ttactagcag tttgatgcta
     8281 tcacttacta gttaatgttg tccttaaagg actttggtat cagcttatgc tcacaccgtt
     8341 ttaattaagc acaagactta atctgaagaa caaattaagt tttgtgtcat atttttacca
     8401 agaagctttg acaacacctg gaatttgacc tttgtaagcc aattcacgga agcaaacacg
     8461 acaaagttta aacttgcggt aaactgaatg tggacgtcca catttttcac agcgagtata
     8521 agcttgtgta gagtgttttg caggacgttt gttcttagca atcatagatt ttttagccaa
     8581 tttatttacc ccctattatt ttgcaaaagg cattccaagg cccttaagca attcacgtga
     8641 ttcttcgtca gtatttgcag tagtgacgat tacaatatca agaccacgta ctttatcaac
     8701 atcatcaaag ctgatttctg ggaagataag ttgttctttc acaccgagag tgtagtttcc
     8761 gcgtccatca aacgattttg ttggaacgcc atggaagtca cgtacacgag gaagtgaaac
     8821 gctaaccaat ttgtctagga attcgtacat acgttcgcca cggagggtaa cttttgcacc
     8881 gatcgctaca ccttcacgaa gacggaagcc agcgattgat ttcttagctt tagtaataag
     8941 tggtttttga cctgagataa gcgctaattc agctgcagct ttctctaggt tttttgcgtt
     9001 ggatacagca tcaccaacac ccatattgag aacaattttc tcaacttttg gcacagccat
     9061 aactgatgtg taattgaatt tctctgtcaa cgcaggaatt acttcgttag tatatttttc
     9121 ttttaaacga tttgccatta tgcttctcct ttccttcgtg attaatcaag cacttcgcct
     9181 gattttttgc tgtaacgtac ttttttaccg tcaacaactt tataaccaac acgtccagct
     9241 acaccatttt tatctaatac ttgaacatta gagacatgga taggtgcttc tttttcgacg
     9301 atagctcctt gaggattttc agtgttaggt ttttggtgtt ttttaatcat tccaacacct
     9361 tcaacaataa ctttgttaac ttttggaagt gctttaagaa ctacagcttc agtgcctttg
     9421 tccttgccag caattacgcg aactttgtcg ccttttttta caaacattct ggtttctcct
     9481 attatttctt acgccccgat gggcacccta ggaaaaccta ggggactacg tttgttaacc
     9541 tgagattaaa gtacttctgg tgcaagtgat acgatcttca tgtagccacc ctcacgcaat
     9601 tcgcgtgcaa ctgggccaaa gatacgagtt ccgcgaggag ttttatcatc acggatgatt
     9661 acagcagcat tgtcgtcaaa tttgatgtat gaaccgtctg gacggcgtgc accagttttt
     9721 gtacgaacga taacagcttt aaccacatca ccttttttaa ctgctccacc aggagtagct
     9781 tgttttacag aagcaacgat tacgtcaccg atgttagcga atttacgtcc tgaaccacca
     9841 agtactttga tagtcaagat ctcacgagca ccgctattat cagcaacttt caagcgagtt
     9901 tcttgttgaa tcatttcaat tttctccttt tagtttgatt agataataac agctttttcc
     9961 actacttcca caagacggaa acgttttgta gctgaaagtg ggcgagtttc catgatacga
    10021 acgatatcgc cttctttagc aacgttgttt tcgtcatgtg ctttatattt tttagaatag
    10081 ttgatacgtt taccatagac tgggtggtta cgtttagttt caactacaac tgtgattgtt
    10141 ttgtccatct tgtcagacac tacgcgtccg taaagagttt tacgttgatt acgttccatt
    10201 tagaatttct cctttcccaa tctattattt catttctgat tgcacagttt taacacgtgc
    10261 aatttgtttc ttaacttcgt caaggcgagc agtcttttca agttgacctg ctgcagcttg
    10321 gaaacgaaga tcaaacaatt cttttttgag ctcgttttct ttcttagcaa gttcttcttg
    10381 agacaatcca cgaagctctt taacaaaatc tttaatttct tgaagtttca tgtcttctcc
    10441 ttattctgct tcacgtttta cgaatttgca cttaactggt aatttgtggc tagcaagacg
    10501 taatgcttcg cgagcaattt cttcagaaac accagcaatt tcaaacatca ctttaccacg
    10561 tttaactggt gctacccaac cttcaggtgc ccctttacca gaacccatac gtacaccgat
    10621 agcttttgca gtgtatgatt tgtgtgggaa gattttaatc caaactttac caccacgttt
    10681 catgtaacga gtcatcgcaa tacgggcagc ttcgatttga cggtttgtaa tccagtggct
    10741 agttgtggct tgaagtccgt attcaccgaa tgaaacttct ttaccacctt tagcctcacc
    10801 gcgcattttt ccacggaatt cgcgacggtg tttaacacgt ttaggtacta acatttgtta
    10861 tttgcctcct ttagtgtttt tacgagctgg aagaacttct ccacggtaaa tccaaacttt
    10921 aacgccaagt ttaccataag ttgtgtcagc ttcttcccaa gcatagtcga tatcagcgcg
    10981 aagcgtgtga agtggaacag ttccttctga ataaccttca gcacgagcga tatcagcacc
    11041 gttcaaacga ccagaaactt gagttttaat ccctttagct cctgcacgca ttgtacgttg
    11101 gattgcttgt ttttgagcac gacggaaagc aacacgttgc tcaagttgac gagcaatgtt
    11161 ttcaccaaca aggtgagcat ctaaatcagg ttgtttgatt tcgatgatgt tgatgtgtac
    11221 ttgttttcca gttaatttgt taagttgacc acgaagagcg tcaacgtttg cgccaccttt
    11281 accgataacc atacctggtt tagcagtgtg aagtgaaaca ataactttgt ttactgcacg
    11341 ttcaatttca atagttgaaa ctgatgcgtc agctaattct ttattaatga atttacggat
    11401 tgcaagatct tcatgaaggt aatccgcgta ttctttttca gcataccatt tcgcatccca
    11461 gtcacggatg attccgacac gcataccaat tggatgtact ttttgaccca cgattttacc
    11521 tccttatttt tctgatacaa ctacagttac gtgagttgta cgtttgttga ttggtgaagc
    11581 tgaacctttc gcacgtggac ggaaacgttt cattgttggt ccttcgttag cgaatgtttc
    11641 agatactacc aagtttgctt tttccaaacc aaagttgttt tctgcgttag caattgctga
    11701 gttaagagtt ttctcaataa cacgagctgc tttgtttgga gtgaatttta agattgcgat
    11761 tgcgtcagca actttcttac cacggataag atcaagtact aaacgtgttt tacgaggtga
    11821 aacacgcact gtacgagcca ttgctttagc tgaagtaatt tctgccattg tgtcctcccc
    11881 ctattaacga cgtgttttct tgtcgtcagc tgcgtgacct ttgtaagtac gcgttggtgc
    11941 aaattcacca agtttgtgac ctaccatgtc ttcttggatg taaacaggta catgtttacg
    12001 tccgtcataa actgcgattg tatatccgat gaaacttggg aaaatcgttg aacgacgtga
    12061 ccaagttttg attacttttt tcttttcgtc gtttgcttga gcttcaactt ttttcatcaa
    12121 atgctcatcg acgaaaggtc cttttttaag actacgtccc attttgtagt tttctccttt
    12181 aaataatgta ccacagcggc ttgagttcaa gagcaagact ccaaaactct accgagttgg
    12241 cggaataaat agcaaagcta ttgtaacgct atttcagcaa gttttaagca acttactaag
    12301 attatttttc gttacgacga cgaacgataa gtttgtctga tttagctttc ttgttacgag
    12361 ttttaagacc aagcgctggt ttaccccatg gagttgatgg cgctttacgt ccaactggtg
    12421 ctttaccttc accaccaccg tgtgggtgat cgttagggtt cattacagaa ccacgaactg
    12481 ttgggcggat acctttccaa cggctacgtc ctgccttacc aatgttaaca agtgattgtt
    12541 gttcgttacc aacagtaccg atagttgcac ggcatgtacc aagaatcata cgaacttcgc
    12601 ctgattgaag acgaacaaga acgtatttac cttcttgacc aagtacttga gcagaagctc
    12661 cagctgcacg aacaagttct ccacctttac caggtttcaa ctcaatattg tgaacaactg
    12721 taccgacagg aatgtttgct aatggaagtg cgttaccaac tttgatatct gcatctggac
    12781 cagaaacaat acgttgacct acttcaagac ctttaggtgc aatgatgtaa gctttcacac
    12841 cgtcagtgta atgtacaagt gcgatgtttg cagtacggtt tggatcatat tcgattgttt
    12901 taacaactgc ttcaacgcca tctttgttac gtttgaagtc gatcaaacgg taatgacgtt
    12961 tgtgtccacc accttggtga cgaactgtga tgcgaccatt gttgttacga ccagctttgc
    13021 tcttaagaga aacaagcaat gatttctcag gcgtgcttgt tgtgatttcc gcgaaatcca
    13081 aagaagtcat gttacgacgg ccatttgtcg ttggtttata aactttaata cccacgttat
    13141 ttcctcctta gattattcag cttcagctgc gaacaactcg attgctttag aatcagctgt
    13201 aagagtgatg atagcttttt tagtttttga agtgaaacct gtgtaacgac caacgcgttt
    13261 tgcttttggt ttaacgttaa cagtgtttac acttgcaact ttaactccgt caaaagcagc
    13321 ttcaacagct tgtttgatca aaagtttgtg tgcacgagta tcaacttcga aagtgtattt
    13381 gcctgcttca agagcaatca ttgacttctc agtgataact ggttttttga ttacgtcgta
    13441 caaattcatt atgcaagaac ctcctcaatt gtagagattg cttctttagt aacaagaagt
    13501 ttgtctgcgt tcacgatatc aagaacactt gcagttgctg cagttgcaac agttacgttt
    13561 ggaaggttac gtgcagaaag tgctgcaaat tcatttcctt cttcaacaag aacaagtact
    13621 tttgtatcaa tgctaagagc tgaaagcact tttgcaaatt cagcagtttt tggtgctgca
    13681 aatgaaaggc cttctacagc tacaaattta tcttcagcaa cttttgctga gtaaactgat
    13741 ttcaacgcaa ggcgacgaac tttttgtgga agtttgtatc cgtatgaacg gggagttggt
    13801 ccaaagacaa caccaccacc acgccattgt ggtgagcgga tagaaccttg acgagcgcgt
    13861 ccagttcctt tttgacgcca tggtttacgt ccaccacctg atactgctga acggttttta
    13921 accgcatgag taccttggcg aaggctagcg cgttggctaa ttacaacatc aaaaacaact
    13981 gattcgtttg gttcgatacc gaagatagcg tcgtttaatt caactgagct aacttcttta
    14041 ccagtttggt caaatagttt tacgtttgcc attttaactg ttttctcctt tcttattatt
    14101 tagcagcttt aactgctgac ttgatagtga taagagattt cttagcacct ggtacgttac
    14161 ctttaataag gataacgttc ttttctggga taacttgtac aatttcaagg ttttgaactg
    14221 ttacacggtt accacccata cgtcctgcca agcgtttgtt tttgaaaacg cggttaggcg
    14281 caacaggtcc catagaacct gggcgacgat ggtaacgaga accgtgagcc ataggaccac
    14341 gtgattgacc atggcgtttg ataacacctt ggaaaccttt accttttgat gtccctgtga
    14401 cgtcaacaac atcaccagct tcaaattgtt ctacagataa ttctgcacca acttctaagc
    14461 cttcaatgtt tttgaattca cgaatgaagc gcttaggagc tgtgtttgct tttgcaacat
    14521 ggcctttggc aggtttgtta ctcaagactt cacgtttgtc atcaaaacca acctgaactg
    14581 cttcataacc gtctgtttca acagttttaa cttgaagcac aacgtttgga gttgcttcaa
    14641 tgacagtaac agggatgaat tcgcctgatt cagtgaagat ttgagtcatt cccacttttt
    14701 tccctaagat tccttttgtc atgagaaaat atttcctttt cttaataata tttcaaaaag
    14761 ttttttatga gcgttttttg tgctcaaaaa agttttttac gagcgttttt tgtgctcata
    14821 gcaagataca aagagcgtca aactcaaaat aaaaatagaa aatctaacac aaaaacttct
    14881 gtttcgagga agatttatct ttttcatgta gagtttagct cgtgttcaag ttccatcaaa
    14941 cactaactgt acttgcaaaa tctcaccgat taaagtttga tttctacgtt gacaccactt
    15001 ggaagatcaa gtttcatcaa agcatcaaca gttttttgtg ttggattgat gatgtctacc
    15061 aaacgtttgt gtgtacgcat ttcaaattgt tcgcgagaat ctttgtattt gtgagtcgca
    15121 cgaataattg tgtaaagact gcgttcagtt ggaagtggaa ctggtccagc aactttagca
    15181 cctgtacgtg ttgcagtttc aacgattttt tctgccgctg tatcaagtgt acggtgttcg
    15241 tacgctttca aacggatacg gatttttttg tttgccatct tttctcctct cgtctattta
    15301 cgataatagg ctagctcctc aagaaaaccg acacctgttg cgtggcaatg caaccgagcg
    15361 tgtcgcaacc tcttgtatca ttgctaaagc tgtattttta cagcaccaca atataataac
    15421 agaatcattt agtcattgca agctttttag ggcatttttt caaaaaaact accttcctaa
    15481 tgaaaggtaa tttcttggta ctttttaaat tgtttagaga gaataaacca ccgactggta
    15541 ttatctaaca ctgtcgccat ccagacccct atgagtccat attgccaaac cacaccaatc
    15601 acataaccaa ggccaatgcg aatcacccac attcctatgg ttgttgcata gaagggaagc
    15661 tttgcttttc ccaaaccctg ccagacggct gtataaacta aagtgcctgc cgttgcggga
    15721 gctcctagta aagaaaaaag taaaacaacc atggcggacc tttgagcatc agtattctga
    15781 gtaaatagcg gcaagagact aggacctagc agataggtca aggctcccat aaccagcatc
    15841 atgagggtgg ataaaataaa agcttctcta ataatatacc ttatctcagt caccttaccg
    15901 ccccccagtt gcctggccac tagaataatt gttgccgttg ccatggctaa gccaggcatg
    15961 taattaaact gagtcaaggt ttctccaata gcattacctg ccaaggccgt tgtcccaaaa
    16021 cgaacaacaa tgccaataat taggacatct cctgctctca tcatcaaacg ttcaccagca
    16081 gcaggtagtg ataaatcaaa aataattttg tccaaaggtc tcatcaatcg tttcgcaacc
    16141 tgtttaatag gaataaactg acaaagtaaa aacacaccca ctaaacgaga taaaaccgtc
    16201 gcccaagcaa caccaagaag accaaatccc catacataga tagacaaggc agaaaaaatg
    16261 gcattgagta cgtttattaa taagctcact tgcataggaa tcttaggata cccttgagct
    16321 cgaacaatag ctcctaagct agttaaaagt cctagactaa caatcatacc gccgacaatg
    16381 gatagatatt gccctccaac caatgttaca gaagcttcag ctcctagcca ttctaacacc
    16441 tgatgatgtc caacaactga taacaaccct aagccgaccg aaaggaggag tgttacttgc
    16501 aagacacctg ccatatagtt taattgtttg ttctgattat tttctccaat acttcgagca
    16561 atcagactag atacagcggc tcccagcgcg ataaagaggg actgataaat actgataatg
    16621 ttgttagcta tggagacacc agagactgct acaagtccaa tttgagccac caggtaatta
    16681 tcaaccattc ccattaacat ctgtaaaata ttttctatca tagaaggcag agctaaagag
    16741 aaaatttttc ttctattata tatcatttat gtcccctaat aaaaaattct tgatcaaacg
    16801 atttttttaa acacagtcac tggactcatt cagttatttt gttccattaa tgaattcata
    16861 aagtctacct taatagcaga gtcccaagat acacgacact tagtgttaca gtaacaattg
    16921 accacatgcc aatccttaac atttacctaa cgtttataac taagaagacg aagaacaaaa
    16981 ggactccaaa cgaatttttt ctattatata atatattctt catttagcaa ctttcaatgt
    17041 atcaaaatag cactctcgag tcaaaaatgt tttctgatac tcgagagtgc tattttattt
    17101 ggaaccaaat ttaagcaact taggcttatc tcatatttaa tacatttgta tgtttagctg
    17161 atgaaatcta agaccttgcg cccttggatt aaaccacgtt ccatttcatc aaagacttct
    17221 ggagcagtgt caactggaac tttttcgaca atcggaacaa ccagaccttc tgcaccaaag
    17281 gcaaaggctt cttccaagtc tttacgtgtc cctacaagtg atccgaccac tttgatacca
    17341 tctaaaacag tttttacgat agacagttcc atgtattctg atggaagacc tacggctaca
    17401 actgtcccac cggcacggac actatcaatt gcttggttaa aagcaacttt agaaacagcc
    17461 gttaccacaa caccatgtgc tccaccggtt ttttcttgaa tatagcctgg aacatcttca
    17521 atttctttgc cgttaactac aatatctgcg ccaacttctt tagctaactc aagtttatca
    17581 ttattaatgt ccactgcgac aacatgtgca ttaaagactt ttttagcgta ttgaacagcc
    17641 agatttccaa ggccacctgc cccaaagata acaatccatt ggcctggagc agcacctgcc
    17701 tctttaatag ctttataagt tgttacacca gcacaagtaa tggaagaagc ttgagccggg
    17761 tctaaacctt ctggaacttt aactgcataa tcagctgtta ctactgcata ttcactcatt
    17821 cctccatcaa cactgtatcc agcattttta acactacgac aaagtgtctc acgtcctgta
    17881 gtacagtatt cgcaatgacc acatccttca aagaaccatg caatagagac acgatcacca
    17941 acctttaagg atgttacgcc ttctccaatt tcttctacta taccaatacc ttcgtgcccc
    18001 aaaatacgtc ctggtacctg accaaaatcg ccatgtgcaa cgtgtaaatc agtatgacaa
    18061 acgccacagt attctacttt aacaagcgct ttaccatgac caacatttgg aagatcatgc
    18121 tcaacaactt cgacacctgt actagcttga ttaacaacta cggctttcat atcagtcctc
    18181 catctaataa tgactttttt gtaatcggtt acaaataaat tgtacatctt ttcacaatga
    18241 aagtcaatag aaacctgaaa agtttctgaa acttaactgg ttaatcttat agctgtttgc
    18301 ctatctgcaa aatacttaac tacattttct gacactggat ataaatgata tatttagaaa
    18361 ataaaatgat ttcttatgac tttaatcata agaaatcatt tcctggtatc aacattaaaa
    18421 atcacttacg tcgtcctgga cgttcagcat aaccatagta agcatcttca ataatttctt
    18481 gcatgtgatc aaccattgga agacgtgggt tagcaggtga acattggtct tcataagcaa
    18541 ggtaagccaa ttcacgagaa tgttctttcc attcgttttc gtcgatacct tgagctttga
    18601 agttcatttg aataccaact cggcaaccca gatcataaac agctttcgca taagattcca
    18661 ctgcttcttc tggtgtagaa gctggaagcc ctaacaattt cgcaatgtct tggtattttt
    18721 catccgcacg gtagtaatta tacttaggcc atgttgctgt tttagctgga cgagttccat
    18781 tatagcggat aacatacggc aaaagaattg catttgtacg tccgtgtacg gtatggaatt
    18841 gtgcgccaat tttatgcgcc attgagtgag aaatacctaa gaatgcattg gcgaaagcca
    18901 tacctgccat agttgacgca ttgtgcatct tttcacgtgc ttcaaaatcg gctgttttaa
    18961 ctgatttttc aagattatca aaaacaattt taatggcttg aagagctaaa ccatccgtaa
    19021 agtcattggc catttgtgac acgtaagctt cggttgcgtg tgtcaaaacg tccataccag
    19081 tatcagcagc aataaagcct ggaacagtca ataccaaagc tgggtcaaca atggctacag
    19141 ttggtgttaa tgagtaatca gcgattggat atttacgatt atttgctttg tcagagataa
    19201 cagcaaatgg tgtcacctct gaacctgttc cagaagttgt tgggatagca acaaattttg
    19261 ttttcttacc aagttctggg aatttgaacg cacgtttgcg gatatccatg aatttttgaa
    19321 cgaggtcatg gaaatcaact tctggttgct cgtagaagag ccacataact ttggctgcat
    19381 ccataggaga tcccccgcca agggcaataa tggtgtctgg tttgaaggta cgcattaatt
    19441 cagtaccttt cataacagtt gtaatgtctg gatctggttc tacttcagca aagatctgat
    19501 aaacaacttt attgcgacga agatcaagtt gttcaatgat acgatccaag aaaccaagct
    19561 caaccatagc gtgatctgta acaatcatga cacgttcaac gtcacgacat ttttgcaaat
    19621 attgaattga atcacgttcg aagtatgttt ttgaagggac tttaaaccat tgcatattat
    19681 ttctacgtct tcctactttt ttgatgttca agagattaac agcactaacg ttatcaccaa
    19741 ctgcgttacg tccatacgaa ccacaaccaa gagtcaatga tggtaagaaa gcattgtaaa
    19801 catcaccgat accaccaaat gtagaaggtg aattccagat gacacggata gcacgaattc
    19861 tagtaccaaa ttcttttgcc aactctgcat ctgctgtatg aatggcagct gagtgaccaa
    19921 gtccattaaa ttcaaccatt tgacgagctt tttcaacacc gtcttcacgt gattcagatt
    19981 tcaaaacagc aatgactgga gataattttt cacgtgttaa aggctcattt tctgaaactt
    20041 ctttacattc tgcagcaaga atattggttc cttctggaac agtaaatcca gcttgttctg
    20101 caatccaagt agctggtttt cctacaatat ttggatttaa ttttgcacca gcacagtttt
    20161 tgctatttgc tttggcacca aaacagaatt cttcaagaag ggctttttct tttttattta
    20221 caaaataagt atggtaagat ttgaattctg ctacaaaatc gtcatagatt tctttatcga
    20281 tgataacagc ttgttcagag gcacagacca taccattatc aaatgattta gacatcacaa
    20341 tatcatgagc ggcttgacgg atattagctg atttttcaac ataagctgga acgttaccag
    20401 cacctacccc aagggcaggt ttcccacatg agtatgccgc tttaaccatc gcatttccac
    20461 ctgtcgcaag gatagtggca atgccgtcat gattcatcaa agcatttgtt gcttcaagtg
    20521 atggtgtttc aacccactgc acacaatttt caggagcacc agcggcaata gcagcatcac
    20581 gaacaatacg agcggcatgt gctgatgatt cttgtgctga tgggtgaaag gcaaaaataa
    20641 ttggattacg tgtttttaac gagatcaaag atttaaagat agctgttgaa gttgggttag
    20701 ttgtgggtgt aatcccacag ataacaccaa ccggctcagc aattaatgtc aaacctgtca
    20761 catcatcttc ttcaataatt cctactgttt tttgatggcg catgttatta accacatgct
    20821 cacaagcaaa tagatttttt gttgctttat cttcaaagac accgcgacct gtttcttcat
    20881 aagcatgttt agcaagttca ccgtgagcat ccaaagcagc aacagaagct ttggctacga
    20941 tatagtcaac ttgttcttgg tcaagcttac gcatctctgc aagagcagct aaaccttttt
    21001 gaacaagagc atcaattgtc acagaaacag aggttgtttc aacagtatta tgtccttcag
    21061 tcatttgaga ctcctttatc ttgttaaaag tttcacaatt ttgtttacaa aattattata
    21121 gcactttttg aaattttgta aatcatttca caataaattt gtgaagtttt tttcaaatta
    21181 tttctgaaat cctatggtat caatattctt cattaacttt ttttcagaaa tatatctaaa
    21241 aaaagccgtt ttatttctga aaccgctttc ttttaaaaaa cctcaaagta ctactatttt
    21301 acaatcatca tttgttcaca agaaaaagcc agagcacaat ggatctgact tatctcttag
    21361 acatttctta actttattta gctggttttt tagctgattt ctcaacagca gtctggattg
    21421 tggagacata tagttctgct ccttgactat cttcactata atgaacaccg tcactgccat
    21481 accaaatatc tggatgttca acagcaactt tataccagtc tgcaatagtg acatacttgt
    21541 attttttgga caatttaaga ccatagtctc tagcttctgc aacctgactg gcatttttgg
    21601 cattatatgg agaaaccaaa actaaacgat gaccatttgg caatgcctca ataaaagact
    21661 gaactgcttg agaatagttg tcaagcgagt taacacctac tgctaagaca acagtcttag
    21721 atagactctt agatttaatt tggttattaa ataaatcgaa agcttcttta aaattccgac
    21781 tgaccgctgc atccagttgc gcttgtggca taatttttga gaatgctgca ctagagcgta
    21841 atgctacaga atcaccaata atacctacgt cactcaaagc attagcgtct cctgcagcta
    21901 gtgtatgtgt ccgctccata ttactttgag cctgttgtag ggaactaacc aacaattgtt
    21961 tctcaaactt accaacttta ggcgctatca tacaagttcc taaagttaat aatgctaagg
    22021 cgagagtccc tcctacaatc cacttatagt aaggagaaca gtcaatttct aaaccaagca
    22081 ggtttggttt tctcccttgg accaaaggtt ctacaatata gtaagacaca gtggcaaaca
    22141 agattgaaaa gaaaactgtt agaataactg ccaaaatatg agacattaat tggctaaaaa
    22201 taatgtaaaa tggccaatgg aagaggtaaa tcccatagct aatatcagct atataagtga
    22261 tagctttagg ctcttgtaca tctggtgttt gctcatgaag aacacgcgct gcataaatca
    22321 taattgatgc gaataaacta gccaaagcaa agccaaatag ataggtcgtg atatggttaa
    22381 aatccaatgt gaccgttagc acaagcaaaa gtgtaaatgc tccaaccata gcagcaagga
    22441 catactggcg cggccataaa cgtacatttt tttgaaatcg aacagtagtc tcgttaatac
    22501 ctgttatcgt ggcaaacatc gcccctaaaa agaagggaaa actgtgagaa agactcgaaa
    22561 aataaatcag ggaaaaattt gaggtcataa aagatcttat aaacatgctc aagaaactaa
    22621 tagcaaatat tcccaaagaa atcaaaaaca gtagtcctct cagttgtttc tgagtctcct
    22681 tgcgtctagc taataaccaa acaaatacac cccaaaacaa gtaaaaatga acttcaatag
    22741 ctaagctcca cgtatgaaca aagagatgtg gaataaattg gctttcataa ctacttcccg
    22801 tcaatatttc ataaatatta gtggtaaatc ctaaaacagc tgtaatctga cttcctatat
    22861 tagcaatgaa atccttctta attaaaaacg taaaaggaat ggtcaataaa atcattaaca
    22921 ccaaaggagg aacaattcga taaaagcgtc tttttaaaaa accgataata tcgatagact
    22981 ctttttttgt gtattcatca atcaagaggg ctgtgattag atatcctgaa aaggtgaaga
    23041 aaatgtcaac accaataaaa cctcctggaa atacattttt aaaaaagtgg tagagtaaaa
    23101 ccagtaaaag tcctgttacc ctaacaaacg aaaaccattt tattctcatt tttgaaatat
    23161 cccctgttta aaaatccctt tatagacttt attattcttt gcttttaaca cacctttgcc
    23221 atttgcttgt cctttatgaa attccccgtt atataaccag cccgtcttag cagtaaaagt
    23281 tccttttcct tcaaataggc cattcttaaa agtaccctca tagatatcac cgttggggta
    23341 gacaagcttc ccttctccat tcattttatg gttaatcacg taaccagtat agtgcatacg
    23401 ccctttatca taggtcaaac ttgtcttatt cgaaattctt acgctaaaaa cagaaattgc
    23461 acaaaccaat atgacaatca ccgagacaat ttccaacttc gcccgtgtaa tactccattt
    23521 ttttactata tcttgcatat ttatcatttc ttttactcaa cttctaatta tcaatactct
    23581 ttattcatta aacgagaaag ccaatcctgg catccttttc taactaattg gtaggtttct
    23641 tcaaaatcgt tagtgtacca aggatcagga acaccccctt ctctaaacag atagatttta
    23701 gagtcccatt gatgttgcga catctctttg agatttttca cattatcgct atccatacca
    23761 ataatatagt caaaggtgtt aaaatcagtt atagttatct gcttggagca tttagttata
    23821 tcataattaa tttggtaagt ttttaatatg gactgtgtac ctgagtgaat aggttttcca
    23881 tgctcccaat cagaagtagc acgactttct atcatcataa catcacttga tactattgac
    23941 ttcattacaa actcagccat ggggcttcga caaatattac ccagacagac aaaacatact
    24001 tttttcatta aatactcctt tgaattatta tatcaaattt ctaactgata tcggagaaat
    24061 caatctaata attttctgtc aacttatcaa aaaatccgaa cacaaaaagc aggttcagat
    24121 taattttctt agatttgaaa aatcattaag tgttttgata gggatagcca agatgacgat
    24181 aagccttttg agtcgctaca cgacctgttc gtgttcgcat gagaaagcct ttttgaatta
    24241 agtagggttc atacatctct tcaactgtat tacgctcctc ggcaatattc acagataatg
    24301 tccccaaacc aactggtcct ccctgataca tctcaatcat cgttcgtaaa attttctgat
    24361 caatgtaatc gagaccttcg cggtcaacat ctaacatagt caaagctcta tcagttattt
    24421 gagccgttat gatgccatca ccaataattt gagcatagtc acgcactcgt tttagtaatc
    24481 gattagcaat gcggggcgtt cctctactgc gacaagctaa tttccgtgca gcttcatggt
    24541 ctatttttat ttcaaaaata gtagctgtac gctccacaat ctctgtcaaa tccttttctt
    24601 gatagtattc catgtgacca gtgataccaa aacgagctct gaggggatta gataacatgc
    24661 ctgcacgtgt agtagcacca atcaatgtaa atggaggcag atccaaatga atactacgac
    24721 tagtatctcc agcgccaatc ataatatcaa tatagaagtc ttccatagca ctatatagta
    24781 cttcctcaac agacattggc atgcggtgaa tttcatcaat aaacaaaata tcccctggtt
    24841 ctaattcatt taaaatagct accaaatctc cagctttctc aacggcagga cctgaagttt
    24901 gctttaaatt aactcccaat tcattggcaa tcacaaatgc cattgttgtt tttcccagtc
    24961 ctggaggtcc aaataataaa acatggtcta aagattcgtc acgtctttta gctgcttcta
    25021 taaaaatagc gaattgttcc ttaactttat cttgtccaat atattcgcgt agatattgag
    25081 ggcgaagagt ccgatccgaa aactcctcat ttcccattac atcattgtct aaaattctag
    25141 ccataggact attataacat aaagtaaaag agagcagtgg cctactttta ttataatcgc
    25201 caccagtcaa cagcactaag ctcttgaact actttaaaag atagtagagc tgcgaatata
    25261 aaatagtact tatacttttt taacatggat aaaaactcct taataattat tttttatatt
    25321 aggaattata tcttactatt aaatatttaa aaatgacatt tttgtcctgt taataacttt
    25381 taacatcttt ttcccactct tgaattaact tgttttccaa at
//
LOCUS       DAUGUF010000027        25285 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUGUF010000027 DAUGUF010000000
VERSION     DAUGUF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25285
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.027"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            181..429
                     /locus_tag="VIB71_001215"
     CDS             181..429
                     /locus_tag="VIB71_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ8822950.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            466..1077
                     /gene="amaP"
                     /locus_tag="VIB71_001216"
     CDS             466..1077
                     /gene="amaP"
                     /locus_tag="VIB71_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEQ8822951.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQIS
                     GVKEGIEKGITEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1088..1276
                     /locus_tag="VIB71_001217"
     CDS             1088..1276
                     /locus_tag="VIB71_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEQ8822952.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1289..1828
                     /locus_tag="VIB71_001218"
     CDS             1289..1828
                     /locus_tag="VIB71_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8822953.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1869..2069
                     /locus_tag="VIB71_001219"
     CDS             1869..2069
                     /locus_tag="VIB71_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8822954.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKIK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2080..2568
                     /locus_tag="VIB71_001220"
     CDS             2080..2568
                     /locus_tag="VIB71_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ8822955.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2731..3360
                     /locus_tag="VIB71_001221"
     CDS             2731..3360
                     /locus_tag="VIB71_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8822956.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNL"
     gene            complement(3515..4057)
                     /locus_tag="VIB71_001222"
     CDS             complement(3515..4057)
                     /locus_tag="VIB71_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8822957.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAKIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4175..4876
                     /locus_tag="VIB71_001223"
     CDS             4175..4876
                     /locus_tag="VIB71_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822958.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4891..7527
                     /locus_tag="VIB71_001224"
     CDS             4891..7527
                     /locus_tag="VIB71_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ8822959.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNANHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7619..8215
                     /locus_tag="VIB71_001225"
     CDS             7619..8215
                     /locus_tag="VIB71_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8822960.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAVDHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8226..9182
                     /locus_tag="VIB71_001226"
     CDS             8226..9182
                     /locus_tag="VIB71_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ8822961.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9279..10619
                     /locus_tag="VIB71_001227"
     CDS             9279..10619
                     /locus_tag="VIB71_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEQ8822962.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELQKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVISLTNQLDKLALEKDATFHSKLATIEKERDGIKNQL
                     VLQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDTNGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10735..11619
                     /gene="truB"
                     /locus_tag="VIB71_001228"
     CDS             10735..11619
                     /gene="truB"
                     /locus_tag="VIB71_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEQ8822963.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11648..12580
                     /locus_tag="VIB71_001229"
     CDS             11648..12580
                     /locus_tag="VIB71_001229"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEQ8822964.1"
                     /translation="MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12623..13027
                     /locus_tag="VIB71_001230"
     CDS             12623..13027
                     /locus_tag="VIB71_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEQ8822965.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDVDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            13029..13307
                     /locus_tag="VIB71_001231"
     CDS             13029..13307
                     /locus_tag="VIB71_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEQ8822966.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13297..14085
                     /locus_tag="VIB71_001232"
     CDS             13297..14085
                     /locus_tag="VIB71_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEQ8822967.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            14088..15398
                     /locus_tag="VIB71_001233"
     CDS             14088..15398
                     /locus_tag="VIB71_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEQ8822968.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSQEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
     gene            15537..16403
                     /locus_tag="VIB71_001234"
     CDS             15537..16403
                     /locus_tag="VIB71_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEQ8822969.1"
                     /translation="MKMKKKFFLLSLLVLSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            16414..17349
                     /gene="pstC"
                     /locus_tag="VIB71_001235"
     CDS             16414..17349
                     /gene="pstC"
                     /locus_tag="VIB71_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEQ8822970.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLLGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            17339..18226
                     /gene="pstA"
                     /locus_tag="VIB71_001236"
     CDS             17339..18226
                     /gene="pstA"
                     /locus_tag="VIB71_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEQ8822971.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            18242..19045
                     /gene="pstB"
                     /locus_tag="VIB71_001237"
     CDS             18242..19045
                     /gene="pstB"
                     /locus_tag="VIB71_001237"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822972.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            19058..19816
                     /gene="pstB"
                     /locus_tag="VIB71_001238"
     CDS             19058..19816
                     /gene="pstB"
                     /locus_tag="VIB71_001238"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822973.1"
                     /translation="MTESILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            19884..20537
                     /gene="phoU"
                     /locus_tag="VIB71_001239"
     CDS             19884..20537
                     /gene="phoU"
                     /locus_tag="VIB71_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEQ8822974.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            20742..23279
                     /locus_tag="VIB71_001240"
     CDS             20742..23279
                     /locus_tag="VIB71_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEQ8822975.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIGNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNHHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQSNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQSTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            23625..24299
                     /locus_tag="VIB71_001241"
     CDS             23625..24299
                     /locus_tag="VIB71_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8822976.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
     gene            24292..>25285
                     /locus_tag="VIB71_001242"
     CDS             24292..>25285
                     /locus_tag="VIB71_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8822977.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKYRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVNRSLRMDKA"
BASE COUNT         8033 a         4172 c         5197 g         7883 t
ORIGIN      
        1 taacatttta taggattttg aaatatcggt attcaaacaa aaaataaact aacactttat
       61 tatttagttt atatagtcac tttttgaaag tcgactatta aaagactatt gcttgaagaa
      121 taacagctgt tattcttcct tggacaaaag gtacaggagt atctaaaaag gagaattatc
      181 atgggactta tttggacttt aatcgtcggt gcgcttattg gtgtgattgc tggagcactt
      241 actaaaaaag gtggttcaat gggctggatt gcaaacatcg ctgctggtct agttggttct
      301 tccgttggtc aagctttact tggttcatgg ggcccttctt tagcaggaat gtctttgatt
      361 ccgtcagtta ttggtgccgt tatcgttgtt atgatcactt cttttgtact aaacaaaact
      421 aacaactagt ttcctcttta tttagtaagt acttacaaat agagaatgtt aagtagaaaa
      481 gaggtctgta tgtcaaaatt gttaaagatt agttattgtc ttgtcggact tgttctattg
      541 tctgtttttg gatgggtagt tggaataacc ggaggctata tatatttacc ttatagttat
      601 cgttggctaa gttggggtat ggatagtttt cccaatctct tagattcagc tttatcctat
      661 tattacttct ggacagccct tgtattattt gttataacat ttcttgcctt attagttatt
      721 attttatacc caagaattta tactgaggtc cagttacgcc ataaaaataa aaaaggaaca
      781 cttttattaa aaaaatcggc tattgaaagt tatgttgcga ccgctattca aactgcaggt
      841 ttgatgccaa acccaacagt cacagctaaa ttatataagc ggaagtttaa gattatcgtt
      901 aaaggacgtt tagcttctcg tgtagcagtg gcagatcaaa ttagtggcgt gaaagaaggg
      961 atcgaaaaag gtataaccga gttcttcgga attaattatc ctgttaattt caaagtttat
     1021 gttaaagata ttgctgattc tgatcgtaaa catattacca gaaatcgtgt agaataggag
     1081 atctatcatg gaattttatg aaaaattcaa gtaccctatt attggtggct tggtggggct
     1141 aattattgcc atattgctca tggcttttgg tttattcaaa acgctactag caattatttt
     1201 cattatttta ggaatatatg gtggcctgta tgccaaaaaa acaggtatta ttgatcaatt
     1261 tcttaatcgt aaataaagga gacttattat gactgaaact tatatcaaaa acacatctaa
     1321 agacttaact tcagcaattc gtggccaatt aacatatgat gataaagtaa ttgaaaaaat
     1381 tgttggttta gcacttgaaa atgttgatgg gttactgggt gtaaatggtg gtttttttgc
     1441 taacctaaaa gataaattag taaacaccga atctgtacgt gatggcgtga acgtggaagt
     1501 tggaaaaaaa caagttgccg ttgatcttga tattgtcgct gaatatcaaa agcatgtgcc
     1561 gactatttat gactctatta aatcgatcgt tgaagaagaa gtgaagagaa tgaccgatct
     1621 ggatgtgatt gaagttaatg ttaaagtagt cgacattaaa acaaaagaac aatttgaagc
     1681 tgaaaaagta agtttacaag acaaagtttc agacatggca cgttcaacat ctgaatttac
     1741 gagtcatcaa gttgagaatg ttaaagcttc agtggataac ggtgttgaaa aacttcaaga
     1801 tcaaaaagct gagccacgtg taaaataatc atatgtcgtc aattaggtaa gctaaaggag
     1861 ggtttattgt gtcagatgaa aaatataatg cgaaattaga tcaagctggt ggcaagttaa
     1921 aagaaggatt tggtaagatt tctggagata aatctttaga aactgaaggt aaagtagata
     1981 aagttactgg aaaaattaaa gaggttattg cagatgccaa agatactgta aaaggattag
     2041 ctaaaggctt agataataaa gataaataaa ggggacatga tggaaaaaac tcaaattaaa
     2101 agcactctta cttatgacga taaggtcatc gaaaaaattg tcggtcatgc tttggaaaac
     2161 gttggcggat tactagctgt aacaggtgga tttttctcaa atatcaaaaa taatttggtg
     2221 aattctgagt ctgtaactga tggtgtttca gttgaagttg gtagcaagga agtagcagtt
     2281 gatttagcaa tcattgtaga atacggtaaa gatattcctg ctattgcaga atctattaaa
     2341 gctattgttt ctcaaaacgt tgacagtatg acacatttga aagttgttga agtcaatgtg
     2401 aacgttgttg atattcgtac taaggaagaa catgaagctg ctagcgttac tgttcaagat
     2461 cgtgtcacta gtgcagcttc aagtacttca caatttgtat cagaacaaac agaaaaatta
     2521 aaagatacta tctctgatac tgtaaatagt gatgaggcag ctaaataagc aatcgtctag
     2581 gaagtattat tgactagtgg tgataagttt gagctggtat ttaccagctc tttttgtcac
     2641 ggttaaaaag atacggacta ttgtcatctc tctaaaaata tgatttaatt agatataaat
     2701 ttttcaaatt gttagaaagg agtaaattaa gtgataagtc ctaaaaaaga gataacaagt
     2761 tcaaaatatc aaaaaattgc tatttcagta gctcagcgta tcgcaaatgg cgaatatgaa
     2821 gtgggcgaaa agttaaagtc aagaactact atcgcctcga catttaatgt atcacccgaa
     2881 acggctcgta aaggcctgaa tattttagct gacttgaaaa ttttgacttt aaaacatggt
     2941 agtggagcta ttgtgctgtc aaaagaaaga gctattgagt ttataaatca atacgaatca
     3001 acccattcca tcgctgtttt aaaagaaaaa atacgtgaga ctattaatga tcagggaaaa
     3061 gcaatggaaa aaatggctgt tttggtcaat gattttttaa tgcaaagtca atctgttagt
     3121 aagcaatacc cattagcacc ttatgagatt atttgtagtc aagattcgga acattttggc
     3181 aaatctatcg gtgtgttaaa tatctggcac cagacaggag caactatcgt cgctattgaa
     3241 catgctggtc agtttatcgt ttcaccaggt ccttattctg ttattgaaaa aggcgatcat
     3301 atttatttcg ttggtgatga gtcagtcatt tcacgaatga agaccttttt taatttatga
     3361 aaaggattat aagtttgagg gcccacctca aacttttttt gttgctgttg agcattatta
     3421 aaagaggcag atcatcatgg tttgtctttc caaaatatct gtttagacag ttgttttgga
     3481 ttgggagcat gatttcagac tcttttgatg ttttttaatt gtctagagta actgctttga
     3541 gaataatatc ggcaacctct tcagtggttt cttgatagcc attagcaatc caatagctga
     3601 taatgctctc aatactggca aggtaaactt ctaaagcata gggataagga atatggtatt
     3661 gattggtcac aatgtcttgg aaaccagtaa tagtagtcaa aaattggtaa cagaaatcct
     3721 tgatgagttg cggaaatttg aggtaagaaa tagtagcgag tgcggttata aattctctat
     3781 gttctataag gtaggacaag gtttgattga ggacttgtcg agtgtctgtg tagattttag
     3841 cctgatttaa caaacggtac aaatcatcca gagtgtcatt tttgaagtga ttcatcatgt
     3901 caaatttatc agtgtagtgg aggtagaagg ttcctctatt gataccagcc tttttagtaa
     3961 ggtcagagac agtaagagtt tcaaaagatt gttcagttag taaggtggtt aaggcggtct
     4021 ttacataagc tttggtttca gtatgtcttt tggtcattct caggtgctcc ttaaatcaac
     4081 agttgcgtca gatttgttct tgttaaatac ttagggccat tatataataa ggctataatt
     4141 aaatcaacac tatgttcaaa taatggaggg gcagatggct tttattgaat taaaacaggt
     4201 ttcaaaatct tatcaggtag gagagacgac tgtttttgcc aaccacgaag tgtcttttga
     4261 gattaataaa ggagaactag tggttatttt gggagcatcc ggagctggta aatcgacagt
     4321 cctcaatatt ttggggggca tggacacagt agatgcaggt caagtaatta ttgatggcaa
     4381 agacattgct cattacacgt ctaaggcctt aactcagtat cgtcggaatg ctattggttt
     4441 cgtttttcaa ttttataatt tggttcctaa tttgacagct aaagaaaatg ttgaattagc
     4501 agttgaaatt gtagcagatg ctttagatcc tgtgaccatt ttaaaggaag taggactcag
     4561 tcatcgtctg gatcattttc ctgctcagct ctcaggtggt gaacagcaac gggtttcgat
     4621 agcacgtgcc ttagctaaaa accctaaatt gcttctttgt gatgaaccta caggtgccct
     4681 tgactaccaa acaggaaagc aaattctaac cctcttacag gatatggcac gaactaaggg
     4741 gaccacggta gttattgtaa cccacaatgc tgctattgct ccgatagctg atcgtgtcat
     4801 ttttatgcat gatgcacagg ttaccaagac agtcattaat aaggaacctg caagcattga
     4861 gacaattgat tattaagagg aaggtgtcgt atgataaaga aaaccttatg gaaggatatt
     4921 ttgagagcta tcaagaatag taaagggcga ttcatttcct tatttttcct aatggcctta
     4981 ggctcctttg ctttagttgg acttaaagtc accggtccag atatggaacg aacagccagc
     5041 cgttacctcg aaagacacca ggtgatggac ctaacggtac tggcttctca tcaattttcc
     5101 caagccgata aacaagagtt agatacgtta aaaggggctc atttagaata tggtcattta
     5161 cttgatgtca gtctaactag caaccagaaa tctcttaggc tctatagcgt gccaaagaaa
     5221 gtgtctaagc cagtcttggt taaagggagt tggccaaagc gagagacaga tttggtttta
     5281 tcctcctcac ttgctaaaaa ctatcagatt ggagatgaac tagcagtcac ctcacctatg
     5341 gaaggtttgc tgacgacaac gcattttcaa gtggttggtt ttgcgaattc ttcagaagtt
     5401 tggtccaagt ccaatttagg aagttcctca accggagatg gaagtctcta cgcttatgct
     5461 tttgttaatc caaacgtttt taaaagtgcc tttaacctgc tgcgcatccg ttttagtaat
     5521 cttcgtctga caaacgcttt ttccaaagac tatcaaaaaa gggtaaccca aaaccaagct
     5581 catttggata atctacttaa agataatggc cagaagcgtt atgatgacct ccaaaatcag
     5641 tatgaccttg ccttaaaaaa tggcagagca gcacttgcaa aggaaacagt gaaactagct
     5701 gcgagtgagg agaacttaac ttttttagaa ggctctgctt tacaagaagc taagcatcag
     5761 attgaacaag gcaaacaagc attagccaag gaggaaaagc agttagagca ggtgcaggct
     5821 acaaaagata agctagaaaa acccagttac ctgacttata atcgctcgac cctaccagga
     5881 ggagaaggat atcatactta tgcaacttca acgacctcca tttcaaatgt tggaaatatt
     5941 tttcctgttg ttctttatct cgtagctgct ctagtagcgt ttaccaccat gacacgttat
     6001 gttgatgaag aaagaacaag ctctggtcta ttaaaagcca ttggttattc taacaaggat
     6061 atcagtttaa agtttcttat ctatgggctt ttagccagtt ttttagggac aactttaggt
     6121 attattgggg gaacttacct cttatctgcc ttgatttcag agatcttaac aggagctttg
     6181 actattggaa agactcacct ttatagttat tggttttata atggcatagc ttacttgctg
     6241 gctatgttat ctgctgtttt accagcctac ttaattgtca aaaaggaatt attcctcaat
     6301 gcagctcagt tattgctgcc caaacctcct agtaaggggg caaaaatctg gttggaacac
     6361 cttacttttg tctggaaagc cctgtccttt actcacaagg tgaccatacg taatattttt
     6421 cgctataaac aaagaatgct gatgaccatt gtaggcgttg cgggctcagt agccctttta
     6481 tttgcaggct tagggattca gtcgtcatta gccaaagtag ttgagcatca atttggtgat
     6541 ttaacgactt atgatatttt ggctgtcggt tcggccaaag cgacagcgac agagcaaacc
     6601 gacttagcta gctatcttaa acaagaacct attacagggt accaaaaggt atcttatgcc
     6661 agcttaaccc ttcctgtaaa gggattacct gataagcaaa gtatttccat tttatcaagt
     6721 tcagctactt ctcttagccc ctattttaat ctgctggata gtcaggagca aaagaaggtt
     6781 cccattccaa cctctggtgt tttgatttct gagaaattag cctcctatta caaggtaaaa
     6841 ccaggtgatc agttggtatt gactgatcgg aaaggacagt cttataaagt gacgattaaa
     6901 caggttattg acatgacagt tggccattac ctgataatgt ctaataccta ttttaagaat
     6961 cattttaaag gattggaggc tgctcctgcc tatctgatta aggtaaaaga caaagatagc
     7021 aagcacataa aggagacagc cagtgacttg ttaaccttaa aagcgattag agcagtttca
     7081 caaaacgcca atcatattaa atctgttcag ctagtagtca cctctcttaa tcaggtcatg
     7141 accctccttg tcttcttgtc tattttatta gcaatcgtta tcctttataa cttaacgact
     7201 attaatattg ctgagcgtat tcgagaatta tccactatta aagttctggg attttacgat
     7261 caggaggtca ccttatatat ttatcgagaa actatttcgc tatccctagt aggcattctt
     7321 ttaggtatct atttaggaaa aggcctgcat acttatatca tgacaatgat ttcaactggg
     7381 gatattcaat ttggtgtaaa ggttgatgct tatgtttatc tagtgccaat tctagtaatc
     7441 cttagcttgt tagcggtatt aggtatctgg gttaatcgcc atttaaaaaa ggttgatatg
     7501 ttagaagctt tgaaatccat agattgattg gtgaaaagac agagatagac agcacttgaa
     7561 aagttaatca tattatgata gtatctaaat actatgattt aatagaaaga tactatatat
     7621 ggaaaatagc attgaggcct atctagcaga tagcagagaa aaggtaacat taggtacagt
     7681 tgttgattgt tttaaaggaa aagcagtctc aagtaaggtt gtgccaggtg atgtgggatt
     7741 gattaattta tctgacatgg gcaccttagg aattcaatat caccaattaa gaactttcca
     7801 gatggatcgt aggcagctct tgcgttacct tttggaagac ggagatgtct taatcgcctc
     7861 taagggaacc ctaaaaaaag tctgtgtttt tcataagcaa aatcgagatg tggtggcatc
     7921 atcaaatatc actgtcttac gccctcaaaa actgttaagg ggctactata tcaagttctt
     7981 tttggactca cctattggtc aagcgctctt ggacgcagtg gaccatggca aagatgtgat
     8041 caatctctca acgaaagaat tgttggatat tccaattccc gttattcctt tagtgaaaca
     8101 ggactatttg attaatcact acttgagagg attaacagat tatcatcgta aactcaatcg
     8161 agcagaacag gagtgggaat atattcagaa tgaaattcaa aaaggattag gttaggagtc
     8221 ttgtcatggg ttcagttgaa cgtacattaa aaatgacctt ggctaccatt gttgccattt
     8281 taattgctta ccaacttcat ctggattatg caatgtcagc ggggatcatt gccctgttaa
     8341 gtgttttaga cacccgtaag tccagtttgg tggtcgctag gaatcgcttg ctatcttttt
     8401 tcctggcttt tgggattgcg atgatgtgct ttagcttgtt tggttttacg acagtaggtt
     8461 ttatgtgtta tttgttaatt attattcctt tgctctatca ctttcagata gaggcaggac
     8521 tggttcctat aacagtactt gtgacacatt tgattgctaa aaagagtatt gcattaccta
     8581 ttttatcgaa tgagtttatg ctcttttttg tagggactag tgtcgcttta ctatttaatg
     8641 cttatatggg tccacaagat cagcaaattc ggtactatca ccaaaaagtt gaatcggatc
     8701 tgaaaggtat cttataccgt tttgaaagtt ttctgctgga aggaaaaggt caaaatgaag
     8761 ggctcttgat caaaaacctt gataaaatat tagatgaagc tctaaaacta gtttatcgag
     8821 aaaggcataa tcaactattt cagcagacca attatcaagt tcattatttt gagatgcgac
     8881 gacaacaaaa tagactattg ggacaaatgg ctatcaacgt aaacacgtta atgagacaaa
     8941 gtaaggaaag tattcttttg tcacatcttt ttcacgaaac tgcttgtcag ctaagcgaac
     9001 aaaatccggc tttaaccttg attgatgaca tcgaacaatt gcttgaaacc tttcgtcatg
     9061 gtgatcttcc tcaaactcgg gaggaatttg agcgacgtgc ggttttattt cagctcttac
     9121 aagacttgga acgttttatc ttattaaagg tagagtttta tcaggattat caaaatgact
     9181 aaatctctat tgcacacttc ttatctatga cagcttggga cttaacttcc tgagcttttt
     9241 tgctataata aaaacaagaa tctcagaatg gagacaagat gaacgaaata aaatgccctc
     9301 attgtcatac cctatttact atcaatgagt cagagtatag tcaattattg gaacaagtca
     9361 gagggcaagc ctttgatgaa gaattgcaaa aacggctaat caatgagata gccttgctag
     9421 aagaaaaagc gaagcatcaa ttgcatgagg ttgtcgcaaa aaaagaaaca gctattacca
     9481 gcttgacaaa ccaattagag caaattgaaa aagaacaagc ctacctcaga caagaagaac
     9541 tggctaaaaa agaccagctt attgcttctt tagaagcgaa acttgataaa ttagcctcac
     9601 aaaatgcttt ggaactggcc aatcaattag ctgagaagga caaagaagtg attagtttga
     9661 ccaatcagct ggacaaatta gcacttgaaa aagatgctac gttccactca aagcttgcta
     9721 caatcgaaaa agaacgcgat ggaatcaaaa accaattggt gcttcaagct aaagaaagtg
     9781 aattgtcgtt ggcttcggtg cgcagcgact acgaagcaca gttaaaagcg gctaacgagc
     9841 aagttgaatt ttataaaaat ttcaaagcgc agcaatctac caaagcaatc ggagagagtc
     9901 tagaactcta tgctgaaaca gagttcaata aagtaagaag ctatgctttt cccaatgcta
     9961 gctttgtcaa agataaccaa ttgtctagtc gtgggtcaaa aggggactat atttaccgag
    10021 aggttgatac caatggtgta gaaatcctct ctatcatgtt tgagatgaag aacgaggcag
    10081 acaccaccaa aacaaaacat aaaaatagtg attttttcaa ggagttagat aaagaccgtc
    10141 gcgaaaaaga ttgtgagtat gctgttttgg taagcatgtt agaagctgat aatgattact
    10201 acaatacagg gattgttgat gtcagtcatg agtatcaaaa gatgtatgtg gttcgtcctc
    10261 aactctttat tcagttgata gggattctgc gaaatgcagc cctgaatagt ttacattata
    10321 agcaagagtt ggccttgatt aaggaacaaa atattgacat cactcacttc gaagaggatt
    10381 tggaccaatt taagaatgcc tttgctaaga actatcagtc tgccagcaac aactttaaaa
    10441 aggctattga cgagattgat aaatcgatta aacgcatgga ggaagtgaaa cgctttttaa
    10501 ccactagtga aaatcagtta cgcttagcta ataataaatt agaggatgtt tcagttaaaa
    10561 aactgacccg ccaaaaccca accatgcgag agaaatttga agccctcaag gaccagtaag
    10621 cctgaaagtg agtctttccc tgctaaaatt ggttaagcgt ttattttggc aaaactgatg
    10681 ataaagcggt agaatagaat cagtaataat tactaattag agagaaaaat agacatgata
    10741 aatggaatca ttaatttaaa aaaagaagcc ggcatgacct ctcatgacgc agtttttaaa
    10801 ttacggaagt tattacaaga aaaaaagatt ggacatgggg ggaccttaga tcctgatgtg
    10861 gtcggtgttc taccaattgc agttggtaag gctactcgtg tgatcgaata catgacagaa
    10921 gctggtaaag tttatgaagg acaagtgact ctcggttact caacaacgac tgaggatgct
    10981 agtggagagg tagttgcgag gtcctctttg ccagctgtgc taacagaaga actcgttgat
    11041 caaacgatga cgactttcct tgggaaaatc acacagaccc cacctatgta ttcagccgta
    11101 aaggttaatg gccgtaaatt atacgagtat gcgcgtgctg gtgaaagtgt ggaacgtcct
    11161 agaagagaag tgactatttc tctgtttgaa cgcaccagcc ctttgaattt tactgaagac
    11221 ggtctttgcc gattctcttt taaagttgct tgtagcaaag ggacttatgt gcggacctta
    11281 gcagttgatt taggtcgagc tctaggggta gagagtcata tgtccttctt gcagcgatca
    11341 gcttcagcag gattaaccct cgagactgcc tatactttgg gagaaattgc tgatatggtt
    11401 tctaaacaag agatgtcttt tttgttaccg atcgagtatg gcgttgctga tcttcctaaa
    11461 atggttattg atgatactga attgactgaa atttcatttg gtcgccgtct tagtctccct
    11521 agtcaagagc cactgttagc tgcttttcat ggcgaaaaag taattgctat tttagaaaaa
    11581 agagatcaag aatacaaacc caaaaaagtt cttatttaaa tagtttgagt aagtagaatg
    11641 gataattatg gaaattgaat atatcaaaga ttatcgtgat attaaccaag aagatgatac
    11701 agtcttgata ttgggatatt ttgatggatt acaccgtggt cataaagcct tatttgacaa
    11761 agcaagagag gttgcaaata aagaagggtt aaaagtagtc gtttttacgt ttacagagtc
    11821 tccgaaattg gctttttcgc gtttttctcc tgagttattg cttcatatta cttatccaaa
    11881 gaagcgttat gaaaaatttg ccgattacgg tgtaaataaa ttatatttgg ttgattttac
    11941 ttctaaattc tctaaggtct catctgatca ttttataact cattatatta aaaacctgaa
    12001 agcaaagcat attgttgtcg gttttgacta taagtttggg cataatcgta cagatagtga
    12061 ttatttaacc agaaattttg aaggacaagt ttataccatt gaggaaataa aagaagatca
    12121 tcgaaaaatt tctgctacat ggataaggaa gcttattcaa gaaggtaatg tagttaaagc
    12181 aaaccacttg ttaggctatg acttatcgac aaggggaaga gtcgttcacg gggatgcgcg
    12241 tggccgtact attggtttcc caacagccaa tctagctcca attgacaaca catacttacc
    12301 agctgatgga gtctatgtta caaatgttat tgttgctaat aaaatctatc gctctatgac
    12361 gagtttaggt aaaaatgtga catttggggg gaaagagttg cgtctagaag ttaacatttt
    12421 tgactttgac gaagagatct atggagaaat tattgagatt gtttggttag ataagattcg
    12481 agacatggaa aaattcgagg gaatcgaaga tttgactgat agattggaat atgataaacg
    12541 aacagcatta aattggaaaa aagatagcaa attatcttaa atttttgtat aataaggtaa
    12601 gtaaatttga tagaggaaaa atatggttac cttattttta tcacctagct gtaccagttg
    12661 tcgtaaagca agggcatggt tagtaaaaca cgaagttgac tttcaagagc ataatattat
    12721 tacaagtcca ttaagccgtg atgaattaat gtcaatcctc tcttttacag agaatggaac
    12781 ggaggatatt atttcaacac gttcaaaggt ttttcaaaaa cttgatgttg atgtagaaga
    12841 gctttcaatt tcagatttaa ttgatttaat tgctaaaaat ccaagtcttc ttcgtcgccc
    12901 tattatcatg gatcaaaaac gcatgcaaat tggttttaat gaagatgaaa ttagagcgtt
    12961 tttatcgaga gattatcgca agcaagaact acgtcaagca acgataaaag cagaaattga
    13021 ggggtgatat gtcaggtaat tattattatc cacttgactt aagttggagc actgaagaaa
    13081 tatcctcagt gcttcatttt ttgaataaag tggagttagc atatgaaaaa aaagtagatg
    13141 caaaacaact cctagatagt tataagactt ataaaaccat tgtcaaaagt aaagctcagg
    13201 aaaagcaaat cgaccgtgat tttcaaaaag ttagtggtta ttcgacctat caagttgtta
    13261 aaaaagcgaa ggcaattgag aaaggattct tttcccttgg aaactaaata cgcatttgca
    13321 aggcaaatca ttaaagaagc agggcttttt atcaagtcaa aaatgtcaga gcagctagat
    13381 attcaggtga aaacacaatt tgatgatctg gttaccaatg ttgatcaaga aactcaacag
    13441 ttactgatgg atcgtattca tcagacctat ccttgtgatg ccattttagc tgaagaaaat
    13501 gacgttcgtc accccattaa tcaaggaaat gtttgggtca tcgatcccat tgatggaacg
    13561 gttaacttta ttgtgcaggg atcacagttt gcagtgatga ttgcctatta tgaacaagga
    13621 attggccaat ttgggcttat ttatgatgtg atggcagatc aattactagc tggtggtggt
    13681 gattttgaag ttactttaaa cggtgataag cttccagctt accaagaaaa acctttagag
    13741 cgtagcttaa ttggctgcaa tgcaggcatg tttgccagaa atgatcgtaa ccttgctcat
    13801 ctaattgcaa agactttagg tgtaagggtt tatggtggtg caggtatctg catggttaag
    13861 gtcatgaagc aggaattact ggcctatttt tcatttatcc aaccatggga ttacgcagca
    13921 gcaaaagtac taggcgataa actgggttat gttttactaa ctattgacgg atatgagcct
    13981 gattttcaaa cacgtcaaaa aatcatgttt gttcctaaat gccaactcac taggatagca
    14041 tcttttctaa caaaggactc tgccgtcaca cttgaagatc aatagaaatg atgtcattac
    14101 caaaagaatt tattaacact tatcaagcaa tactaggcaa agaattagaa gatttcttgg
    14161 caagttttaa ccaagagccg gtcaatgctt ttcggattaa ccccttaaag aatcaactaa
    14221 aaacctttga acaccccatt ccaaatacct tatggggata ttatggtaaa ctatctggca
    14281 agtctcaaga gcatgtgtcg gggttggttt attcccaaga accagcggct caaatggtgg
    14341 cacaagtagc ggctcctcaa aaggggagtc gtgttttaga cttggcagct gcaccaggag
    14401 gaaaatcaac tcatttatta gcttatttag acaatacagg tcttttagtc agcaatgaaa
    14461 tttctaagaa gcgcagcaag gttttagttg aaaatatcga acgttttggc gctagaaatg
    14521 ttgtggtgac taatgaatcc gcagatcgtt tagccaaggt attttctcat tattttgata
    14581 ctatcgtctt tgatggacca tgttctggtg aaggaatgtt tcgcaaggac cctgatgcta
    14641 ttcaatattg gcatcacggg tatcccgcag aatgcgccaa gttgcaaaaa tctattttag
    14701 aagacgcctt aaccatgtta aaaccaggag gagaattgat atactccacc tgtacttggg
    14761 ctcctgaaga aaatgaagat gttgtgcagt ggctcttaga gacttatacc tttttagaat
    14821 tggtcgatgt tccaaaacta aatggaatgg ttagtggtat cggacttcca gagactgcta
    14881 gaatgtaccc tcatcgttat caaggggaag ggcaatttgt ggccaagcta aaagataagc
    14941 gtcaagaagg acaaagcact aaactaaaag cacctaaatc caatttgacc aaagaccagt
    15001 tacgtctttg gaaaatgttt gaaaaagacc atctaaacct taccctatca ggaacactac
    15061 aaacctttgg tgattaccta tacctcttgc cagatggtct tcctgcttta gatggcctta
    15121 aaattgctcg gaacggttta gaattaggcg tcttcaagaa gaaacgcttt gaaccctctt
    15181 acgccttggg attagcttta aagcctgatg aggtccgatc atctattgag cttagagagg
    15241 aagactttag accttatgtg tcaggtaacg tcattacttt gccccaatct tatccaacag
    15301 gctggtacca gttactcatt aatggcaatg gtctaggatt tgccaaggtc gttgacaaga
    15361 ccatcaaaaa taatttccct aaagggttaa gattttagcg taaaaaataa gattaaaaag
    15421 ttaaatattt aaagaaaaaa tgctttcaaa gcataggtag atatgttact ataaagaata
    15481 tgtggcactt agtttctaca tatataccct ttatttttac gaataggaaa taaataatga
    15541 aaatgaaaaa aaagttcttt ttgttaagtc ttttggtcct atcaactttc tttttatccg
    15601 catgttctag ctggattgat aaaggtgagt caataaccgc tgtaggatca acagcactac
    15661 aacccttagt agaagcagta gctgatgaat ttggaagcag taatctaggc aagactgtca
    15721 atgttcaagg tggtggttca ggtacagggt tgtctcaagt tcaatcagga gctgtccaaa
    15781 ttggaaatag tgatgtcttt gcggaagaaa aagatggtat tgatgcttct aaattagttg
    15841 atcatcaagt agctgttgca ggacttgcag ttattgccaa tcctaaagtc aaggtttcca
    15901 atctcagtag tcagcagttg caaaagattt tttcaggaga atataccaat tggaaacaag
    15961 ttggaggaga agatcttgcg atttcagtga tcaaccgagc agcaagttct ggctcacgag
    16021 caacctttga cagtgttatc atgaaagggg tcaacgctaa acaaagtcaa gagcaagact
    16081 ccaatgggat ggttaaatcg attgtttcac aaacaccagg tgccatttct tacctttcct
    16141 ttgcctacgt tgattcatct gttaaatctt tgcaattaaa tgggtttaag gcaaatgcta
    16201 agaacgtggc tacaaatgat tggccaatct ggtcctacga acacatgtat accaaagata
    16261 aaccaacagg gttgaccaag gaatttcttg attatatgtt ttcagatgaa gtacaacaga
    16321 acattgttac acatatggga tatatttcga taaatgatat ggaagtggtc aaatctcatg
    16381 atggaaaagt aacaaaaagg taatggagga attatggaaa atcaggaatt ggctaaaaaa
    16441 ttagcctcac catcaaagaa ttcaaggctt gaaacctttg gccgcaccat tacgtttttg
    16501 tgtctggctt tgattgtttt tatcgttgcg atgattctga tcttcgttgc tcaaaaaggg
    16561 ttgtcaacct tctttgttga caaggttaat ctttttgatt tcttgcttgg aaaggagtgg
    16621 caaccaagtg tgaaaaatgc ggccggcatt ccttatcttg gtgctctgcc aatgattaca
    16681 ggatcctttt tggttaccat tttatctgct attattgcca ccccatttgc cattggcgca
    16741 gccgttttta tgactgaaat ctcacctaaa tatggcgcta aattattaca gcctgcggtt
    16801 gagcttttgg ttggaattcc ttcggttgtt tatgggttta tcggtttgca agtgattgtt
    16861 ccttttatgc gctctatctt tggtggcaca ggttttggaa tcctatctgg ggtctgtgtc
    16921 ttgtttgtta tgattttacc aacagtgact tttatgacaa cagacagtct gcgggcggtg
    16981 cctcgtcatt accgcgaagc gtctatggct atgggagcaa cacgttggca aaccatctgg
    17041 cgtgttgtcc ttaatgcagc tcgtccagga atttttaccg ctgttatttt tggaatggcg
    17101 agagcttttg gagaagcctt ggctatccaa atggtagtcg gtaactctgc tgtaatgcca
    17161 agttcactaa cgacaccagc cgcaacctta acgtctgtct tgacaatggg tattggtaac
    17221 acggttatgg gaacggtcca aaataatgtg ctttggtccc ttgccctagt cttattatta
    17281 atgagtctgg ccttcaattc ccttgtcaaa ttaatcacga aagaaagaaa gagaaattat
    17341 gaacgctaaa aaagtcgata aagtagcaac tggtactctt tataccattg ctggaattat
    17401 tgtagctatt ttagcttcct taattctata tatccttgtc cgtggcttgc cacacatcag
    17461 ctggtccttt ttaacaggaa aatcgtcttc gtacgaagct ggtgggggaa ttggtatcca
    17521 gttgtataat tccttcttcc tattgattgt tactttaatt atttccattc ctttatcaac
    17581 tggagcgggg atttacttgg ctgaatatgc caaaaaaggg cctgttacca actttattag
    17641 aacctgtatt gagattctgt cttccctacc atctgtggtt gtggggctct ttggttactt
    17701 gattttcgtt gtgcagtttg aatatggctt ttctattatt tcaggggctc ttgctttgac
    17761 ggtctttaat cttcctcaaa tgacccgtaa tgttgaagat agtttactgc atgttcatca
    17821 tacccaaaga gaagcaggat tagctttagg cctgtcacgc tgggaaacgg ttttttatgt
    17881 ggttatccca gaagctctcc cgggaatggt aacaggtatt gtcttagctt caggtcgtat
    17941 ttttggtgaa gcggcagcgc ttatctatac tgctggtcaa tcagcaccag ctctggattg
    18001 gtcaaattgg aatccactta gtgttactag tccaatctct attttccgtc aatctgagac
    18061 ccttgctgtt cacatttgga aagtcaatag cgaagggaca attccagatg ctactcttgt
    18121 atccgcagga agtgcagcag tgctattaat ttttatcctt attttcaact tttcagctcg
    18181 ctttattggg aagaaacttc attctaaaat gacagcggcc aaataaaata gtggagaaat
    18241 catgacagaa tacaattgga atgaacgtca tatcatcact tttcctgaag aaacgcttgc
    18301 tctagctacc aaggatttac atgtttacta tggtgcgaaa gaagctatca aagggattga
    18361 tatgcagttt gaaaaacata aaataacagc cttgattggt ccatctggtt gtggcaaatc
    18421 aacttatctt cgtagtctta accgcatgaa cgataccatt gatattgctc gggttacagg
    18481 tgagattctt tatcagggca ttgatgttaa tcgaaaagac atgaatgttt acgagattcg
    18541 caagcactta ggaatggttt ttcaaagacc taatcctttt gctaaatcca tttataaaaa
    18601 cattaccttt gcccatgaaa gagctggtgt gaaagacaaa aaagttttag atgaaattgt
    18661 tgagacttca ctgaaacaag ccgcgctttg ggatcaagtt aaagatgacc ttcacaaatc
    18721 agccttcacc ttatcagggg gtcagcaaca acgcttgtgt attgctagag ccatttctgt
    18781 caaacctgat attctattaa tggatgaacc agcctctgcc cttgacccga ttgcaacgat
    18841 gcagctggaa gaaaccatgt ttgaattgaa gaagaattac acgattatta ttgtgaccca
    18901 caatatgcaa caagcagctc gtgccagtga ttacactgcc ttcttctatt taggcaacct
    18961 cattgaatat gataagacac gtaatatttt ccaaaatgcg caatgtcagt caacaaacga
    19021 ctacgtttca gggcactttg gttagaaagg caatatgatg acagaatcta ttttacagat
    19081 cagagacctt tctgtttact acaatcaaaa gaaaacgtta aaagatgtct ctttggacct
    19141 ttatccaaat gaaataacag ctttaattgg tccttctgga tctgggaaat caacgctctt
    19201 gcgttctatc aaccgtatga atgatttgaa tcctgaagta accattacag gctctatcgt
    19261 ctataacgga cacaatattt atagtccaag gacagatacg gttgatttac gcaaagaaat
    19321 tggtatggta ttccaacaac ccaacccatt tccgatgtct atttatgaga acgtggttta
    19381 cggccttcgc ttaaaaggta tcagagataa atcaatctta gaccatgctg ttgaaagctc
    19441 tcttaaaggg gcttccattt ggaatgaagt caaagatcgt ttacatgatt ctgcggttgg
    19501 cttatcaggc ggacagcaac agagagtttg catagctaga gttcttgcta ccagccccag
    19561 aataatcctt ttagatgaac ctacctcagc tcttgatcct atctcagctg ggaaaattga
    19621 agaaacatta ttgttattaa aaaaagatta tacactggct attgtgaccc gctcaatgca
    19681 gcaagcctca cgtttatcag atcgaacagg ttttttcttg gagggtgact tacttgagtg
    19741 tggtcctaca aaagccatgt ttatgaatcc taagcgcaaa gaaaccgaag actatatttc
    19801 tggtaaattt ggttgagaaa gacgtatatg gttgacccct ctgtgttttt attataatga
    19861 ctagattgta ggaagaaaaa atcatgttaa gaacgaaatt tgaagaagaa ttagataaat
    19921 tgcataacca gttttattca atgggaacgg aagtattggc acaaatcaat aaaactgttc
    19981 gtgcctttgt tagtcatgat cgtgaattgg ccaaagaagt tatcgaagaa gatgacacta
    20041 ttaataattt tgagacaaag cttgaaaaga aatcgctgga aattattgcc ctacaacagc
    20101 cagtttcgaa tgatcttaga atggttatta ctgttttaaa ggcatcaagt gatattgaac
    20161 gtatgggtga ccatgctgct tcgattgcca aggccactat tcgtatgaaa ggtgaggagc
    20221 gtattccagt ggttgaagaa caaatcaacc ttatgggaaa agctgtgaaa cagatggtag
    20281 aagaagccct taatgcatat atcaatgctg acgatacaaa agcttatgaa atcgcagctt
    20341 ctgatgagat tatcgatcaa tatttccgta atatccaaac cttagctgtt gaagaaatcc
    20401 gtaagtctcc agatgctgtt tttgcaggaa aagaatattt tcaagtatta atgtatttgg
    20461 aacgtattgg tgactatgct cgcaacattt gtgaatggat tgtttatctt aaaactggaa
    20521 aaattattga attataagaa attatgctat aatgagactg ggaatcagct tgccagtccc
    20581 tggttttata cgaaattgtg caagttagaa aatgaactaa caagaaaagt tttctttgct
    20641 gaatctgatt ttgttaggtt aacaaatata tgtagacaga gatgatactt aggtatcatc
    20701 tgttgatcta ttatgatttg ttattagaat taaggagtta tatgaagaca gtagaacatc
    20761 tcatcgaaac atttgtgcct gaaaattata acatcttttt agatattaat cgtcagacta
    20821 aaacatttac ggggaatgtt gcgattaatg gtgaagcttt agataatcat gtggctttcc
    20881 accaaaaaga tttggacatt aagtctattt tgctcgataa tgaagctgtt atttatcaag
    20941 tggataacga caatgaagtt gtgcgtgttg aattacctga aacaggaatg atgacgcttg
    21001 tcattgaatt ttcaggtagc attacagata atatgacagg tatttaccct tcatattaca
    21061 ctaaaaatgg tgagaaaaaa gaagtcattt caactcagtt tgaaagccat tttgcgcgtg
    21121 aagctttccc atgtatcgat gaaccacaag caaaagctac ttttgattta agcttgacct
    21181 ttgatcaaga aattggtgag atagcgttat cgaatatgcc agaagtcaat attgaccgtc
    21241 gcgaggagac tggtctttgg acatttgata cgacaccaag aatgtcatct tacttgctag
    21301 cgtttgcgct aggagaactt catggaaaga ctgtagaaag caaaaaagga acaactgttg
    21361 gtgtgtatgc gacaacagcg catcctctta gctcgcttga tttttcattg gatattgcag
    21421 ttcgtgttat caacttttat gaagactatt ttggagtaca ttacccaatc ccgcaatctc
    21481 ttaatattgc gcttccagat ttttcatctg gtgctatgga aaattggggt ttaatcactt
    21541 atcgtgaaat ttatttatta gtagatgaaa attcgactgt tcaaagccga caacaagttg
    21601 cacttgtaat cgcccacgag atagcacacc aatggtttgg aaacttggtt acaatgaaat
    21661 ggtgggacga tctgtggtta aatgagagtt ttgccaacat gatggaatat gtctctatcg
    21721 aggctattga gccgtcttgg aaaataatag aagatttcca aacaggtggt attcctcttg
    21781 ctttaaaacg tgatgctact gatggtgttc aatcagtgca tgttgaagtc aatcatccag
    21841 atgagataaa tacattgttt gatcctgcta ttgtctatgc aaaaggtagt cgtttgatgc
    21901 atatgttacg ccgttttatt ggtgatcgtg attttgccat tggcttacat cactactttg
    21961 aaaaatatca atatcgaaat actgtcgggc gtgatttatg gaatatttta tcagatactt
    22021 caggcaaaga cgtagctgct tttatggatg cttggcttga acaaccaggt tatccagttt
    22081 taacagctcg ccttgaaaac gatcaattga ttttgagtca aaaacaattt tttattggaa
    22141 aaggtgaaga aaaaggtcgc ctttggccga ttcctttaaa cactaattgg catggccttc
    22201 ctgaaacttt gacagaggca gaaatggtca ttccaaactt tagtcaattg gcagcagaaa
    22261 atgaaggagc tctacgtttc aatattggta atacagctca ttacattaca gactaccaag
    22321 gatcattatt agatgcctta gtcactgaac ttgcccaact tgataatact tctgctttac
    22381 aagttattca agaacgtcgt ttattggcag atagtggctt gatttcttat gctgaattgg
    22441 ttgacttaat tgctcaattg gacgattcta agtcttatat ggtagcagaa gcggttcagc
    22501 aagtggtctc tggtttgaaa cgcttcattg atgaaggaag cttagcagaa aaatccttta
    22561 atcgcttggt aaccaccatc tatcaagaag actttaatca ccatggtttt gagaaaaaag
    22621 ctgacgaatc agatgaagat gagatggtac gtcaggttgc cttgggacgc ttgtggttag
    22681 cagaaaatca gacgattatt gacggattga gaactatttt tgaagcatat caaagcaata
    22741 ttgcaagtat tccagcagct gttcgtcgct tggttttagc caaccaaatg aaatattttg
    22801 aaacagatag cttggttgat atttattttg agacttatgt agcaactact gataataatt
    22861 tacgcagtga tttaacggtt gcttttagtc aaacaaaaca atcaactact attagacgta
    22921 ttcttgttag tttaaaagat aaagatatta ttaaacctca ggatttatct tattggtaca
    22981 atgctttgct tggacaaagc tttactcaag atatcatttg ggaatgggct agagaaaatt
    23041 gggattggat taaatctgca cttggtggag atatgagctt tgataaattt gttatttatc
    23101 cagcaagtaa ctttaaaaca ccaaaacatc tagcagaata taaatctttc tttgaaccta
    23161 agctagatga tatggctatt agccgtaata ttaccatggg aattaatgaa attgaagcac
    23221 gtgttgcttt gatcactaaa gaaaaagaag cagttattgc agctctcagt cattactaga
    23281 ccataagcaa aagagttggg ggactttcca gctctttttt gtagtaagct agcttccttt
    23341 cttagttccg tctataacta aatgattatc catagtttaa ttcaaaagga gattgcactt
    23401 taaagcgaag gctattagcc tcttaaatac ttttttacca ggtggtgaat aagaacaatt
    23461 ataaatgatt taatcattat gctttaaatg ccttaaagga gtattaatat tttagtaaac
    23521 cttaagcttt ttgtagtata gtctcgttag aaattgttat cagaaatgag actaagttaa
    23581 atgaagtgat agttacttta tttaagaaca attgaggtag agacatgata aaaatattat
    23641 tagtagaaga tgacttgagc ttatcaaatt ccatttttga ttttttagat gattttgcag
    23701 acgtcatgca agtttttgat ggcgatgaag gtttatacga agcagaaagt ggtatttatg
    23761 atttgatttt gttagacctt atgttgccgg agaaaaatgg ctttcaagtc ttaaaagaat
    23821 tgcgagaaaa agatattaaa attcctgtgt tgatcatgac agctaaagag ggtttagatg
    23881 ataaaggtca cggatttgaa ttaggtgctg atgattatct gaccaagccg ttctatttag
    23941 aagagttaaa aatgcgaatt caagcactgt taaaaagaac agggaaattt gcagataaaa
    24001 atattagttt tggcaattta gtggttgact tagctcgaaa agaggtgaag gttgaaggga
    24061 aagtagttga attacttggc aaagaatttg atttgttggt gtatcttttg caaaatcaaa
    24121 acgttatttt accaaagaca caaatttttg atcgtttatg gggattcgat agtgatacta
    24181 cgatttcggt tgttgaagtt tacatttcta aaataagaaa aaaattaaaa ggtacccgtt
    24241 ttgttaacag gcttcaaact ttaagaagcg tagggtatat tctaaaaaac aatgaataaa
    24301 ttaaaaaaag agattttatc agataactat aaccactttt ttcatttttt tgcggttttt
    24361 acaggtattt ttgtcattat gactattatt atcttacaga ttatgcggtt tggcgtttat
    24421 tcgtcagttg acagtagttt agtttctgtt agtaataatg caagtagcta tgctaatcgt
    24481 acgatggcta gaatatcttc tttttacttt gatactgaaa ataacattat taaggcgctg
    24541 cctgattcag atagttctaa gttattagga acgcctgcag ctaatacaga tatcattttg
    24601 tttagtgcta atggaacaat tttaaatgct tttgatgcgt tttctaacta tcaaaatttt
    24661 catttagata aataccgttt ggggagtatt gaaaccacca gtttaatgaa tttttatgga
    24721 caagaagaaa aataccatac gataactgta agggttcata tcaaaaatta tcctgcagtt
    24781 gcctatatga tggcagtagt aaatgtggaa caattagacc gcgctaatga acgttacgag
    24841 cgcattatta ttatagttat gagtgttttt tggctaattt ctattttagc aagtatttat
    24901 ttagccaagt ggagcagaaa acctatttta gaaagctatg aaaaacaaaa aatgtttgtt
    24961 gaaaatgcta gtcatgaact aaggacccct ttggcggtct tacagaatcg tctggaatcg
    25021 ctttttcgta agcccaacga aacgatatta gaaaatagtg agcatctcgc ttctagttta
    25081 gacgaggttc gcaacatgcg catcttaaca actaatttat taaatttagc aagacgagat
    25141 gatggcatta atccacagtg gactcattta gatacagatt tttttaatgc tatttttgag
    25201 aattatgaac tagttgctaa agaatatgga aaaatatttt attttcagaa ccaagtcaat
    25261 agatcgttaa gaatggataa ggctt
//
LOCUS       DAUGUF010000028        25171 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUGUF010000028 DAUGUF010000000
VERSION     DAUGUF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25171
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.028"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            447..836
                     /locus_tag="VIB71_001243"
     CDS             447..836
                     /locus_tag="VIB71_001243"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEQ8822978.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            930..1982
                     /locus_tag="VIB71_001244"
     CDS             930..1982
                     /locus_tag="VIB71_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ8822979.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2121..3653
                     /locus_tag="VIB71_001245"
     CDS             2121..3653
                     /locus_tag="VIB71_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8822980.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKKLEVDENRGVPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVSPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3646..4710
                     /locus_tag="VIB71_001246"
     CDS             3646..4710
                     /locus_tag="VIB71_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822981.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4712..5668
                     /locus_tag="VIB71_001247"
     CDS             4712..5668
                     /locus_tag="VIB71_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8822982.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5881..7599)
                     /locus_tag="VIB71_001248"
     CDS             complement(5881..7599)
                     /locus_tag="VIB71_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ8822983.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSAGLIQVIGEDVDIEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGTTMFNVLTGFKFIAEKIQEFEE
                     KQNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMNKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7775..8344)
                     /locus_tag="VIB71_001249"
     CDS             complement(7775..8344)
                     /locus_tag="VIB71_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8822984.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8402..8947)
                     /gene="coaC"
                     /locus_tag="VIB71_001250"
     CDS             complement(8402..8947)
                     /gene="coaC"
                     /locus_tag="VIB71_001250"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEQ8822985.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(8940..9632)
                     /gene="coaB"
                     /locus_tag="VIB71_001251"
     CDS             complement(8940..9632)
                     /gene="coaB"
                     /locus_tag="VIB71_001251"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEQ8822986.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNEHLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9813..10664
                     /locus_tag="VIB71_001252"
     CDS             9813..10664
                     /locus_tag="VIB71_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEQ8822987.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKKEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKAFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10661..11860
                     /locus_tag="VIB71_001253"
     CDS             10661..11860
                     /locus_tag="VIB71_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEQ8822988.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     ISYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASYALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11857..12855
                     /locus_tag="VIB71_001254"
     CDS             11857..12855
                     /locus_tag="VIB71_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEQ8822989.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEKAEALAKPLDIWMLGQQDFNEFKTYPEVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12897..13229
                     /locus_tag="VIB71_001255"
     CDS             12897..13229
                     /locus_tag="VIB71_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEQ8822990.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13222..14034
                     /locus_tag="VIB71_001256"
     CDS             13222..14034
                     /locus_tag="VIB71_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEQ8822991.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEASQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKTLYDTYLQKENNCE"
     gene            14027..14908
                     /locus_tag="VIB71_001257"
     CDS             14027..14908
                     /locus_tag="VIB71_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEQ8822992.1"
                     /translation="MSNWTTYPQKNLTQAEQLSQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWMAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKL"
     gene            14955..15974
                     /locus_tag="VIB71_001258"
     CDS             14955..15974
                     /locus_tag="VIB71_001258"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ8822993.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATGVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREYLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            16102..17772
                     /locus_tag="VIB71_001259"
     CDS             16102..17772
                     /locus_tag="VIB71_001259"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ8822994.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            17857..19434
                     /gene="cls"
                     /locus_tag="VIB71_001260"
     CDS             17857..19434
                     /gene="cls"
                     /locus_tag="VIB71_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEQ8822995.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            19774..20112
                     /locus_tag="VIB71_001261"
     CDS             19774..20112
                     /locus_tag="VIB71_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8822996.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
     gene            complement(20520..21788)
                     /locus_tag="VIB71_001262"
     CDS             complement(20520..21788)
                     /locus_tag="VIB71_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEQ8822997.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSIPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYNTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
     gene            21878..22744
                     /locus_tag="VIB71_001263"
     CDS             21878..22744
                     /locus_tag="VIB71_001263"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEQ8822998.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQSPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            22722..23279
                     /locus_tag="VIB71_001264"
     CDS             22722..23279
                     /locus_tag="VIB71_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8822999.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRVPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            23413..24957
                     /locus_tag="VIB71_001265"
     CDS             23413..24957
                     /locus_tag="VIB71_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8823000.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGHLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
BASE COUNT         7787 a         4164 c         5147 g         8073 t
ORIGIN      
        1 atcattatct tctaaggtgt cattgttatg gtgacaatca accatacgct actaaagata
       61 ggtagcgttc gatcacaggt tgatcaagtg attgatacag atatttataa ttttacaaat
      121 atctgtatca atccatgttg aatagtctat gcttctaagg tgtcgacgtt aatgtactga
      181 cgggaccgtt atagtctttc tttttggaga aacgtcggat gccagtgaac tagttgaagt
      241 taaagatgtt aattcaaaca gtgctgaaga gattgatatc gttttgaacg gtcgtttact
      301 tcaaagcaaa gaaattacca gtctatcgga gatgatataa gtgctaaagt tagatcacgt
      361 taattatcta tcaagtcggg tgcatatttc gttaaaatat ctacaggggt ttcaatagat
      421 gtagctatta tgaaaggtga tgttaaatgg ggactactga tttagttagt tgtgctgtac
      481 aagctagtga gtatgcttat gtcccttact ctcattttcc agtaggagca gctttaaaaa
      541 caaaagatgg aacgatctat actggctgta atattgaaaa tgttagtttt ggtctgacaa
      601 attgtggaga gcgaacagct atatttaaag ccatatctga tggtcataaa gaattggttg
      661 aaattgctat ttatggagaa actatgcaac ctgtatctcc ttgtggggct tgtcgtcagg
      721 taatggcaga attttttgct ccttcttctt tagtcacttt aattgctaaa aatggtcaaa
      781 ctgttgaaat gactgttgga gatttactcc cctattcttt tacagattta atataatctg
      841 ctttaatttc tgttatctag ccgtcttggc tttatattta ctttcagcaa cttatttgct
      901 agaaatcttt tttaggaggg ttcatattca tgaacaagaa atttattggt cttggtttag
      961 cgtcagtggc tgtgctgagt ttagctgctt gtggtaatcg tggtgcttct aaaggtgggg
     1021 catcaggaaa aactgattta aaagttgcaa tggttaccga tactggtggt gtagatgaca
     1081 aatcattcaa ccaatcagca tgggaaggcc tgcaatcttg gggtaaagaa atgggccttc
     1141 aaaaaggaac aggtttcgat tattttcaat ctacaagtga atctgagtat gcaactaatc
     1201 ttgatacagc agtttcagga gggtatcaac tgatttatgg tatcggcttt gcattgaaag
     1261 atgctattgc taaagcagct ggagataatg aaggagttaa gtttgttatt atcgatgata
     1321 ttatcgaagg aaaagataat gtagccagtg ttacctttgc tgaccatgaa gctgcttatc
     1381 ttgcaggaat tgcagctgca aaaacaacaa aaacaaaaac agttggtttc gtgggcggta
     1441 tggaaggaac tgtcataact cgatttgaaa aaggttttga agcaggagtt aagtctgttg
     1501 acgatacaat ccaagttaaa gttgattatg ctggatcatt tggtgacgct gcaaaaggaa
     1561 aaacaatcgc agcagctcag tatgcagcag gtgctgatgt tatttaccag gcagcaggag
     1621 gcactggagc aggtgtattt aatgaagcaa aagctattaa tgaaaaacgt agtgaagctg
     1681 ataaagtttg ggttattggt gttgaccgtg atcaaaaaga cgaaggaaaa tacacttcta
     1741 aagatggcaa agaagcaaac tttgtacttg catcatcaat caaagaagtt ggtaaagctg
     1801 ttcagttaat caacaagcaa gtagcagata aaaaattccc tggaggaaaa acaactgtct
     1861 atggtctaaa agatggcggt gttgaaatcg caactacaaa tgtttcaaaa gaagctgtta
     1921 aagctattaa agaagcgaaa gcaaaaatta aatctggtga cattaaagtt cctgaaaaat
     1981 agtgtttaag aacaagaagc gcgacctttg tcggtcgctc tttttaaact gagataattt
     2041 ttatctcagt aaagtttgtg ataggtgata gatcataggc tttactgaaa taaaagattg
     2101 cattgaaagg aaatgatcct atgacacagc atgtcattga aatgagagaa atcacgaaaa
     2161 aatttggtga ttttgttgca aatgaccaca ttaacttaaa tgtcagaaaa ggtgagattc
     2221 atgccttatt gggtgaaaat ggggcaggta aatcaacttt gatgaatatg ctagctggtc
     2281 tcttagagcc tactagtgga gaaattgtca ttaatgacaa gccagttcaa attgattcgc
     2341 catctaaatc agctaagctt ggtatcggaa tggtacatca acatttcatg ttagtagaag
     2401 ccttcacggt tgctgagaat attattttag gaaatgaagt agtaaaaaat gggtgcttag
     2461 atcttaacca agcatcgaaa gatattaagg tactatccga aaaatatggc cttgcaatca
     2521 atccatcagc taaagtttct gatatttcag taggagcaca acaacgtgtt gagattttga
     2581 aaaccttgta tcgtggtgca gatattctta tctttgatga gccaactgcc gttttaacac
     2641 ctgcagaaat taaagaattg atgactatca tgaagaatct cgtgaaagaa ggaaaatcaa
     2701 ttattttaat tacccataaa ctggacgaga ttcgtgctgt cgccgaccgt gtcacagtta
     2761 ttcgtcgtgg taagagtatc gaaacagttg atgtggcagg agcaacttca caagatttag
     2821 ctgagatgat ggtgggacgc tcggtttcct ttacaactag caaaaaagct gctgaaccaa
     2881 aagatgtggt cttatccatc aaaaaacttg aagtagatga aaatagaggg gttccagcag
     2941 ttaaggggct atctctagat gtccgagctg gtgaaattgt agggattgct ggaattgacg
     3001 gaaatggtca atctgagtta attcaagcta ttacaggttt acgtaaagtc aaatctggaa
     3061 gtattatgat taaaaacaat gaagtcactc atttgtcttc acgcaaaatt actgagttat
     3121 cagtgggtca cgtgccagaa gatcgtcatc gagatggttt gatactagat ctttctttag
     3181 ctgaaaatac agccttacaa acctattaca aacaacctct aagtcaaaat ggaatcttaa
     3241 attatactaa aattaatgac tatgctcgtc aattaatgaa agaatttgat gttcgcggag
     3301 ccaatgagct agtaccagct agaggatttt ctggtggtaa ccaacaaaag gccattattg
     3361 ctcgtgaagt ggaccgtgat ccagatttac ttattgttag ccaaccaaca cgtggtcttg
     3421 acgtaggagc tattgaatat atccataagc gtttgattaa agaacgtgat aaaggtaaag
     3481 ctgtcctcgt tgttagtttt gaacttgatg aaatattgaa tttatctgat cgaattgctg
     3541 ttattcatga tggtaaaatt caaggtatcg tatcgccaga aaataccaat aaacaagaat
     3601 tgggtatttt aatggcaggt ggttcaattc ataaggagga aggtcatgtc taaaaatgcg
     3661 caaaaaattg ctgtaccatt gatttctgtc ttgctaggat ttttacttgg cgctattatt
     3721 atggttatct ttggttatga tcctatctgg gggtatgaag gtttattcca aattgccttt
     3781 ggtagtgtta aaaatattgg agaaatattc cgttcaatgg ggccattgat tttaatagcg
     3841 cttggcttta ctgttgctag ccgtgcaggc ttctttaacg ttggtttgtc tggacaggct
     3901 ttagctggat ggatttcagc aggttggttt gcactcttaa atccagatat gcctcgtcca
     3961 ttattgattc ttatgacagc tcttatcgga atgattgctg gtggtattgc tggagctatt
     4021 ccagggatac ttcgtgctta tcttggtaca agtgaagtta tcgttacgat tatgatgaac
     4081 tacatcattt tatatgtcgg aaatgctatt gttcaacgtg gttatcctga gagtgtcaaa
     4141 caaagtattg attcaactat tcaagttagt gataatgcta gttatcaaac gcattggtta
     4201 tcagccctaa ctaataactc tcgtattaat attggtattt tctttgccat tattgccatt
     4261 gccctaatct ggttcttgct taacaaaact actttaggtt ttgagattcg ttcagttggt
     4321 ctcaacccac atgcttcaga atacgcaggg atgtcatcaa aacgtactat cattttatca
     4381 atgattatct ctggagctct tgcaggtctt ggaggagtag ttgaaggtct aggaaccttt
     4441 gaaaatgttt ttgtacaagg atcttcttta gcagttggtt ttgacggtat ggcagttagc
     4501 ttattagcag caaattcacc gcttggaata tttttctcat cattcctatt tggtgtctta
     4561 aatattggtg ctccaggaat gaatattgca ggcattccac cagaacttgt taaagtagta
     4621 actgcatcaa tcattttctt tgttggttca cattacctca ttgaacgtta cattattcgc
     4681 cctaaaaaat tagtgaaagg tggtaaataa gatgagttta gtaacaattt ttgccttatt
     4741 ggtgtcatct atgcttattt atgcaacacc actcattttc acaagtattg gaggaacttt
     4801 ctcagagcgc tcaggcgttg ttaatgttgg tttagaaggt atcatggtca tgggagcgtt
     4861 ctctgggatt gttttcaact tagagtttgc tgaaacattt ggaaaagcaa cgccttggat
     4921 agccgtttta gtcggtggta ttgttggttt gattttttct ttgattcacg ctgtagcaac
     4981 catcaacttt cgagctgacc acattgtcag tggtacagtg ttgaacttgt tagcaccttc
     5041 ttttgctgtc ttcttggtta aagctatgta cggtaaggga caaacagaca acattcaaca
     5101 atcttttggg aagtttgatt tcccaggttt atcacaaatt cctgtgattg gtgatatttt
     5161 ctttaaaaat actagcctta ttggttactt cgccattgct ttttcgttct ttgcttggtt
     5221 tttgctttat aaaaccaggt ttggtctgcg tttacgatca gttggggaac accctcaggc
     5281 agctgacaca cttggtatta acgtctattt gatgaaatac tatggtgtga tgatctcagg
     5341 ttttcttggt ggaataggtg gagctgttta tgctcagtca atctccgtta actttgctgt
     5401 aacaactatc ttaggtcctg gatttattgc tttggcagct atgatctttg gtaaatggaa
     5461 tccagttggc gccatgctat ctagtctttt ctttggctta tcgcaaagtt tagccgttat
     5521 tggtgctcaa ttaccattac tagaaaagat tccaacggtt tacttacaga ttgcacctta
     5581 tatggtaacg attattattt tagctgcttt ctttggtcaa gcagttgcac caaaagctga
     5641 tggaatcaac tatattaaat ctaaataacg ttatattagt aagcctctta gtgaggttta
     5701 acagcactcc taaagcaaga tagttaggtc tagctttaag ggtgcttttt tgggacttac
     5761 cgcaagtttg gattgccagt caccatcaca atagaagcaa gaatagacta aaaagaacta
     5821 agtcagcggc ttagttcttt ttgcttgtct ttcgttttta ctgatagctc ttaagttgtt
     5881 ttagccaaca aaggtattga tttctgtttc aatgttagca attttttctt gagcgatgtc
     5941 aagagtatca cctattgtgg caatatagaa cttgattttt ggttcagttc ctgaagggcg
     6001 aactgcaatc catgaatcat cagctaacgt gtacttcaaa acattacttg gaggagttgt
     6061 taagttagat attgttccat catttttagt agcggtttgt ttttggaaat cttctaataa
     6121 tacaatatca gtattgttaa attgttttgg accattttca cggaatttgt tcataatctt
     6181 cttaatttca gcagctccat ccacacctga aagtgttact gaaatcgttt tttcagcaaa
     6241 atagccatat tctttgtaaa tttcatcaat accatctgca agtgttaaac cacgcgaacg
     6301 gtaataagcc gcgatctcag caaccaaaag aactgcttga atagcgtctt tatcacggac
     6361 aaatggttta ataagatatc cgaagctttc ttcaaaacca aacatatagg tgtggttttg
     6421 tttttcttca aactcttgaa ttttctcagc gatgaatttg aatccagtta aaacgttaaa
     6481 cattgtagtg ccataacttt cggcaatttt tgttactaat tctgttgata cgattgattt
     6541 agcgagagca gcattttctg gaagtgttcc tgctgtttta tgagcttcca ggatgtattt
     6601 cgcaataatc gctccaattt gatttccaga aagattttta taagaaccat ctggttggcg
     6661 aatttcaacg cctaggcggt ctgcatcagg gtcggtagct actaagacat ctgcatcaac
     6721 ttctcgtccg agttcttcag caagagcaaa ggcagcttgg ctttcagggt taggcgattt
     6781 aacagtagaa aagtctggat ctgccttagc ttgtgattcg actacaacaa cagattcaaa
     6841 accggcttga gcaagggcac ggcgtgtcaa catctcacca gttccgtgga gaggagtata
     6901 gacaattttc atgtcttttc caaagttatt gattaaatct tgattgatat taacatcttt
     6961 aacctctcta agatattcaa tatcaacatc ttcaccgata acttgaataa gacccgctga
     7021 tttgctttca tctaaatcag caagttcaac tgcaaatgga ttttcaatag cacggataaa
     7081 gtctgttagt gcatcagcat cagctggtgg tagttgacct ccgtcttgtc catagacttt
     7141 ataaccattg aaaggtgctg gattgtggct tgcagtaacc ataataccag cataggcatt
     7201 taaatggcga acagcaaaag agagttctgg tgttggacga agagcttcaa atacgtaaga
     7261 tttaattcca tgctgtgcca agacctgtgc agactcaaaa gcaaattctg gagagaagtg
     7321 gcgcgaatca taagcgatgg ctacaccacg ttttttagct tcctctccct tagtttcgat
     7381 taattttgct aatccttcgg ttgcttgacg gacaacataa atattaatac gatttgtacc
     7441 agcaccaata taaccacgca taccagcagt accaaattct aagtttgtgt aaaaagcatc
     7501 ttcttttgtt ttttcatcca ttgatagtaa ttcttgacga agatagtcag gaagctgctc
     7561 aaaatctaac catttttgaa aattttctgt gtaagtcatt gaaatactcc ttcaatattt
     7621 ataaacgctt tcattatatc attttgaagg aaaaaaaaca ctaattattt gcagctgttt
     7681 acaaaacttt ttccatattt tcaagtagct aatgtaagaa agttaaaata accaagtttt
     7741 taaaagagaa aaactcggtt attgtgaaag ctaattacct ttttagtctt gatagtgttg
     7801 gaataagtac aaaggtaata atagctgaga tgatcatctc aacaatagcg tttgatgaga
     7861 tgatggctgt tagtagtgct ttaatatttc catcaaaaac tgtcgcgaaa aaaataaata
     7921 tcccagataa tacaaatata gtatttgtta gagaaccaat gataccggat actattaaac
     7981 caaactgatt aggaatcaat ttatagcaat aataaggggt aataccaatc aaaatacgtg
     8041 ggataatagc aattattaaa gaagcgaagg ttccatgatc gacaaaaggt gaaaagagat
     8101 aatttgtagg cagtagaatg atggtatttg taatgacact tataatcccc attaatcctc
     8161 ctaaaatagc acctatcctt gggccatata agacagaagc aataataact gggatatgga
     8221 caagcgttgg tttgattgga ataggccaaa tattaaagac aagactgctc acaaaatgaa
     8281 tgactaacat gatggcaaaa aagatagcaa tacgagaaat atctgctgat ttacggtgat
     8341 tcattttact ctccaaaaaa tataatactt aattctaaaa aggtgatcag aaaaacgact
     8401 gttaaagttt ccaaatcgta tcaatagtag ctaagataac atcaatatca gccaaagcac
     8461 caggtccttt atctccacag gctaataagc tagattttgg aggaatttct gtaaacccta
     8521 ttgtcgataa gcgtttaata ttttcttggg taatagggtt ttgatacatt ttggtattca
     8581 tggctggggc tattaatttt ggtgtggtag ctggtagggc aagagcaaca cttgttacaa
     8641 tattatcagc gaatccatat gctagatgag caatagtatt agcagaggca ggtgcaacaa
     8701 taaataaatc tgtgcgtttt gctaattcga tatggttgat aacttttggg tcatgctcat
     8761 ccataacatc taaatgaata gcattttttg ataacacttg cagggttaat ggtgtaataa
     8821 attgtgtagc agcctgagtc attatgatgt gaacatcata gccaatttta gttaattgac
     8881 tcgtaagatc tgctgcttta taggcagata tactaccaga aacagctaag gtaatatgtt
     8941 tagtcatgtt tggtcatcct ttcatataat aagtcagcaa ttgcctcttt ggtatctgca
     9001 gatgcaactt cgttattgga tatcaaaaga gccttgtgca tacctgtttg gatatcaact
     9061 aaatcattgg cgagaatata atcagcatgg tttttagcta gacttgctct ggctacttta
     9121 attaactctt cttgaggcac attaactaga agtttaaagc cgactagttt aatattagga
     9181 ttccactgtt taacataaga gataactttg ggtgtttttt tcaaaaaaag aacctgataa
     9241 tcagatgcag atgagatttt cggctcactg ttatgttcac atagaaaaca attaaggtta
     9301 tcagcttgag agacttgttc caaatcagtc atgtagactg gagtatagtc agaaacagcc
     9361 atactatgaa ttagaatgtc atggtgagga acctgatctt tgagtgcagc cattaagtcg
     9421 ttaactgttt ccacttcaat aatccttagg tgctcatttg gcaggggttt agtggctgtt
     9481 ttagtagtga ctagggtaac gtcatgatga tattgtaaaa atcgctctgt gattaatttt
     9541 ccaagttgcc cagttgagtg attagtgata cctcgtactg catctatagg ttcagttgtt
     9601 ccacctgatg ttattattaa tttcatagtc atattttatc aaaaaaggag ctgatagtaa
     9661 acggaagata atgacgccag acattgtctt gcgtttgtat taagatggaa tagtaataga
     9721 tttctagtaa ttaaaacgaa gttctggaaa gcaagacact atagtagcta aaatctaaat
     9781 tttaaggtaa aatagggcaa gcggtttcaa gtgtgaaagg aagaattgtg ataactatta
     9841 gagatttagc gtcactgccg atttttgttt acggtgatgg aaataaaaaa gttccaggag
     9901 ctttgagtcc ttttgtgtgg acagaggtgt ttttaaaaac tatcaatcaa gaacctaatc
     9961 aactgatctt acatatttgg ccgatgacaa gaacagttat attaggaatg ttagatagac
    10021 agcttcccta ctttgagctg gctaaaaaag agattggcaa taatggttat gttcctgtta
    10081 ctcgtaatat tggcggtttg gctgttgttg ctgatgatgg gattttgaat ttttcgcttg
    10141 ttattccaga ccatttttcg gaatctatca gtattagtaa tgcttattta ataatggttg
    10201 atgtcattag agagagtttt tcggattatt atcagcgtat tgaatatcac gaaattaaaa
    10261 attcttattg ccctggtaat tttgatctta gtattgcagg ccgcaagttt gcaggtatcg
    10321 cccagcgtcg tatcaaaaag ggaattgttg tgtctattta cttgagcgtt tgtggggatc
    10381 aagcagcgcg tggtcaactc atcaaggctt tttatgaggc tggaacacaa ggagaagtta
    10441 ccaaggttaa ttaccctcaa attgatccag aatgcatggc aactctttca gaactccttg
    10501 agacgccttt tacagtggca gaagtccttg aacgtcttcg attgaccttg cgacagcttg
    10561 gcttttccct cacggaaaaa agtccagatc aagccttact gactaatttt gatgctgtct
    10621 atgaaaggat gcagctagaa gtcgttagaa aggaaggcaa atgaaagaaa gatttagtcc
    10681 tttatttgag cctttgactt tgccaaatgg gagtcaattg gataatcgct ttgttttgtc
    10741 tcctatggtg accaactcat ccacaaaaga cggttatgtc acccaagatg atatatccta
    10801 tgctttgaga cgagcagctt ctgcccctct acaaattaca ggagcggcct atgtggatcc
    10861 ttatggtcaa ttgtttgaat atggttttag tgttacaaaa gatgccgata tttctggctt
    10921 gaaagagcta gctcaagcga tgaaggcaaa gggagctaaa gctgtcttac aactgaccca
    10981 cgctggccgg tttgctagct atgccttgac taaatatggc tttgtctatg ggcctagtta
    11041 catgcagttg agatctcccc aacctcatga agtcaaacct ttaacaggtc agcaaataga
    11101 ggaattgatt gcagcttacg ctcaggccac tcggcgggca attcaagcag gctttgatgg
    11161 cgtggaagta tcttcggcgc agcgcttatt gattcaaacg ttcttttcga ctttttcgaa
    11221 caagaggaca gatagttatg gttgtcaaac actttttaat cgctctaagt taactctagc
    11281 tgttttgcaa gctgttcaac aggtgattaa acaagaagct cctgatgggt ttatttttgg
    11341 atttcgtgct acaccagaag aaactagggg aaatgatatt ggttatagta ttgacgagtt
    11401 tttgcagttg atggattggg tacttaatgt tgcaaaactt gattatttag cgatagcaag
    11461 ttggggccgt catgtatttc gaaatactgt tcgttctcct ggcccttatt atggaaggcg
    11521 agttaatcag gtagttagag attatttaag aaataagcta cctgttatgg ctacaggggg
    11581 aatgaacaca cctgacaaag ctattgaagc actagctcat gctgatttta ttggagtatc
    11641 tacacctttt gtcgtggatc cagaatttgc tcataaaatc aaagaagggt gtgaagagag
    11701 tattcattta aggattcgac ctgctgattt gaaaagttta gcgattcctc aggcttcttt
    11761 caaagatatt gtacctttga tggactacgg ggaatcattg cctaaagaat caagaacttt
    11821 atttcgtagt cttactcaca attataagga gattaaatga aagtcagtat tcttgattat
    11881 ggggtgattg ataaagaaaa aacaccccaa gaagctttat tagaaacgcg ctgcttagca
    11941 caagtagccg acaaacttgg ttttcatcgt ttttgggtag cagagcatca taatatttat
    12001 gcctttgcaa taagcagtcc agagctgttg atgatgcatt tagcagatca taccaaacag
    12061 attcggatag gttcaggagg tattatgcct ctacattata gtagctttaa gattgcagaa
    12121 tggataatga ctttagaggc cttgcaccct aatcggattg atttaggtat tggcaactct
    12181 ttaggaacta cgttagttca aagagctcta tcaagtatcc attgcaaaga cagctatagt
    12241 caggttgtca cagaattata ccagtatctt aatcctgatc atttgtcacc actaccgatt
    12301 tttgttaacc ctaggggtaa tacttaccct cagatttgga cgctaagcaa tagtttggag
    12361 acagcagaac tggctggtca attaggttta ggctatacct ttggtatttt cccctatata
    12421 ccaaaagatc ctataacaga agctaaaaga gtatcggcac attatagaaa ggcttttagg
    12481 ccttcaaagc tattaaaaat ccccaagtta atattagcag tttttattgt cctttctgat
    12541 accgacgaga aagcagaagc tttggctaaa ccgttggaca tttggatgct tggtcagcaa
    12601 gattttaatg aatttaagac ctaccctgaa gttgaggagg ctagaaacta tcacttaaca
    12661 gagaaacaaa gagaagccat tgcagcaaat cgtagtcgca tggttattgg atcacctcac
    12721 acagtcaaga aacaattgga taggctgata gaagcttgtc aagctgacga attattagcc
    12781 atccccttag ttcctgaatt tgccaataga caacgaacct tagagctgct agcagactta
    12841 tacgtgacca tttaacctta ccaaaaacaa ttccctaaac tgaaaggaaa gaaacaatga
    12901 aaaaaattgc aaattactta ttaattgaga aaacagatga ccgctatacc attagcatga
    12961 caccagaatt acaagacgat attggtacta ttggttacgc tgaatttacg gataacgacc
    13021 accttgccgt tgatgacatt atcttaaatc tagaggcttc taagaccgtc atgtctgtct
    13081 tgtcaccatt ggctggggca gttgttgagc gcaatgaggc agccacacta acaccaaccc
    13141 ttttgaattc agaaaaagct gaggaaaatt ggattgttgt gctaacagat gttgatcaag
    13201 cagcttttga tgccttagaa gatgcctagt tcatttgatt tattagggga aatgattggt
    13261 ctgttgcaaa cagagcagct tactagttct tgggcctgtc ccttgcctaa tgctttaaca
    13321 aagcgacaag acttgtggcg ggcgctcatt aaccagcgcc ctgctttgcc tttatcaaaa
    13381 gattacttga atctggaaga tgcttatcta gatgattggc gtgcttcttt tgttcctgta
    13441 tcagtcaagg attgccaaaa aactaattat accagtcttt ttctttacca tggggatatt
    13501 aggtaccttg ctgtggatgc tattgtcaat gctgctaata gtgagttatt gggatgtttt
    13561 attcctaacc atggctgtat tgataatgcg attcatacgt ttgccggaag tcgtttacgc
    13621 ttagcttgtc aggcaatcat gactgaacaa ggccgtaagg aagccattgg ccaagcaaag
    13681 cttaccagtg cttatcatct accagcctct tatattattc ataccgtagg gccaagaatt
    13741 accaaaggac accacgtttc tccgattcga gctgatttgt tagcacgttg ttatcgttct
    13801 agtcttgatt tggcggttaa agcaggattg actagcctag ctttttgctc tatttcaaca
    13861 ggagaatttg gctttcctaa aaaagaagcc tctcagattg ctattaagac agttttaaaa
    13921 tggcaagcag aacatccaga atctaagacc ttaactatca tttttaatac ctttacatca
    13981 gaagacaaga ccttatacga cacttatttg caaaaggaga ataactgtga gtaattggac
    14041 aacctatcct cagaaaaacc tcacccaggc agaacaactg tcccaattaa tcaaagaagc
    14101 agatgcactt gtagttggta ttggagctgg catgtctgca gctgatggtt ttacttatat
    14161 cgggccgcgt tttgagacgg cattcccaga ttttattgct aagtatcagt ttttggatat
    14221 gctgcaagct agcctttttg attttgaaga ttggcaagaa tattgggctt ttcaaagtcg
    14281 ctttgtcgct ttgaattatc ttgatcagcc cgtaggccag tcttatcttg atttaaaaga
    14341 gattttggaa accaaagact atcatattat tactactaat gctgataatg ctttttggat
    14401 ggctggttat gatcctcata acatttttca cattcaagga gaatatggtt tgtggcaatg
    14461 tagccagcac tgccatcagc aaacttataa ggacgatacg gtcatccgtc aaatgatcgc
    14521 agagcaaaaa aacatgaaag tcccaggtca actgattcct cattgccctg aatgtgaggc
    14581 gccttttgaa atcaataagc gtaatgaaga aaaaggaatg gttgaagatg ctgactttca
    14641 tgcccaaaaa gcacgttatg aggctttttt atcagaacat aaagagggta aagtgcttta
    14701 tctagaaatt ggtgtgggac atacgacgcc tcagtttatc aaacacccct tttggaaacg
    14761 tgtctcagaa aaccctaatg ccttattcgt taccttgaat cacaaacatt accgcatccc
    14821 tctgtcaata aggcgacaaa gcctagaact gacagaacac attgcacaat tgattagcgc
    14881 cacaaaaacc atttaccaaa aattgtaacc aaagccaata gacggttaat taagagatag
    14941 agaaggagac taacatgtac cttattgaac cgattcgtaa cggtaaacgt atcaccgatg
    15001 gagctgttgc tctagccatg caagtttatg ttcaagaaaa tctattttta gatgatgata
    15061 ttttatttcc ctactattgt gatcccaaag ttgaaattgg aaaattccag aatgcagttg
    15121 tagaaactaa tcaagagtat ttaaaagagc atcatatccc tgttgttcgc agagatactg
    15181 gcggtggtgc cgtttatgta gattctggtg ctgttaatat ttgctacttg attaatgata
    15241 atggtatttt tggtgatttt aaaagaacct atcagcccgc tattgaagcc cttcatcatt
    15301 tgggagcaac aggggttgaa atgtctggac ggaatgactt ggttattgat gggaaaaagg
    15361 tatctggcgc tgcgatgact attgctaatg gccgtgttta tgggggatat tcccttttgc
    15421 tagatgtgga ctttgaagcc atggaaaaag cattaaaacc taatcgcaaa aaaattgaat
    15481 caaaaggcat caggtcagtt cgtagtcgcg ttggaaacat cagagaatat ttagcaccac
    15541 aataccaagg tattacgatt gaagagttca aagatttaat ggtttgccaa ttgttacaga
    15601 ttgagacgat tagccaagct aagcgttatg atttaacgga aaaagactgg caacaaattg
    15661 atgctttaac agagcgtaaa tatcacaatt gggaatggaa ttatggcaac gcgcctcagt
    15721 accgttacca tagagatggc cgttttaccg gtggaacagt agatattcat ttagatatta
    15781 aaaaaggcta tattgcagct tgtcgcattt acggagattt ttttggcaag gcagacattg
    15841 cagaacttga aggtcacttg ataggaacac gaatggaaaa agaggatgtc ttagctaccc
    15901 tcaatgcaat tgatttagcc ccttatttag gtgcgattac agcagaagaa ttaggagatt
    15961 tgatattttc ttgataaaaa agatacctca gaccggtaaa gtgcgattaa aaacgaacaa
    16021 taattgtttt gattcaaata aatgtacgta tgatatgaat tgtgatataa tgacgtcatt
    16081 acgtaaaatt gaggagtcat catgaaatca gatatcgaaa ttgcccaaag tgtcgcccta
    16141 caaccaatca ctgacattgt taaaaaagtt ggaatagacg gcgatgacat tgagctttat
    16201 ggcaaatata aggctaaatt gtcttttgag aaaatgaaag ctgtcgaagc taatgagcct
    16261 ggaaaattaa tcttggtaac tgctattaac cctactccag caggagaagg aaaatcaacc
    16321 atgtctattg gactggcaga tgccttaaat caaatgggaa aaaaaaccat gcttgcctta
    16381 cgtgaaccct cccttggtcc tgttatgggg attaaaggcg gggcagcagg tggtggttat
    16441 gcccaagtat tgcctatgga agacattaat cttcacttta ctggtgacat gcatgccatt
    16501 acaaccgcta ataatgcatt atctgctttg attgacaatc atttgcagca aggaaacgat
    16561 ttaggaattg atcctcgccg cattatttgg aagcgcgtgt tggaccttaa tgatcgtgct
    16621 cttcgtcagg taattgttgg cttaggcagt ccagtgaatg gtgtgccacg cgaagatggg
    16681 tttgatatca cagtagcttc tgaaatcatg gcaattttat gtttggcaac tgacttgaaa
    16741 gatctaaaga aacgtcttgc tgatatcgtc gtggcttata cctatgatcg taagcctgtc
    16801 tatgtgcgtg acttgaaggt tgaaggagca ttgacattaa ttctaaaaga tgctatcaag
    16861 ccaaacttgg tgcagactat ttatggaaca ccagctctta ttcatggggg gccatttgct
    16921 aatattgctc atggttgtaa ttctgtcctt gctacctcaa cagctttgcg attagcagat
    16981 tacactgtta ccgaagcagg attcggggcc gacctaggag ctgaaaaatt cctaaatatc
    17041 aaagtaccta atcttcctaa agcaccagat gctatcgtca ttgttgcaac cttgcgcgcc
    17101 cttaaaatgc atggaggtgt cgccaaatca gatttagccg ctgaaaattg tgaggctgtt
    17161 cgcttaggat ttgccaactt aaaacgtcac gtggaaaaca tgcgccaatt caaagttcca
    17221 gttgtggtgg ctatcaatga atttgtagca gataccgagg ctgaaattgc taccttaaaa
    17281 gcgctttgtg aagagattaa ggttccagta gaattagcca gtgtttgggc aaatggagct
    17341 gagggaggct tagcattagc taaaacagtg gttcgtgtga ttgatcaaga agctgctgac
    17401 tacaaacgtc tctattcaga tgaggatact ttggaagaaa aagtgatcaa tatcgttacc
    17461 cagatttatg gtggcaaagc tgttcaattt ggccccaagg ccaaaacaca attgaagcag
    17521 ttcgcagaat tcggttggga taaattgcct gtttgtatgg ctaagaccca atacagtttt
    17581 tcagataacc catccttgct tggagcgcca accgattttg atattaccat tcgtgaattt
    17641 gttcctaaaa caggggcagg ttttattgtt ggtttaacag gtgatgtgat gaccatgcct
    17701 ggtttgccta aagttccagc tgccatggca atggacgtag cagaaaatgg cacagccctc
    17761 ggtctctttt aggaaaaatt gctcgaataa ttcgagcaag cgctcctttc ttcccgcttt
    17821 actgtgatat aataaggtaa atgagatttt ggagggatga ttatcaaaaa gaaagcaaaa
    17881 gtaaaatatt tgctccataa agggaaacat ggatttttaa gaggaatttt tagtagaaca
    17941 acaatcattg tattattaat tattttgcaa ttagttttct tatttcaatc ttatgcctgg
    18001 atggagcagt accgtgtttg gataacgatt cttgaaagtg tctttgctat tactattgtt
    18061 ttatatttag ttaatagtga tatggatgct atttcaagaa tgacgtggtt aattttgatt
    18121 atgattgctc cattactagg gtcactgttt ttaatttata caaaattgga ttggggttac
    18181 agagggctaa aacaaagaat aaatcatctt gtagatctgt ctgcacctta ccttagcgat
    18241 gatgacgcta tattagaggt attaaaggat agcacatcaa ccacatatca tttagtacag
    18301 tacttagaaa gaagtcgtgg caactttccg atttataata atacaagggt aacttacttc
    18361 ccaacaggtg aaactttttt tgatagttta aaagaacagt tattcttagc taaaaagtac
    18421 atttttcttg aattttttat tattgcagaa ggccaaatgt ggggagaaat ccttagtatt
    18481 ctagaaaaaa aagtcagtga aggtgtagaa gttagggtgt tgtttgatgg catgaacgaa
    18541 ctatcaacgc tatcatcaga ttacgccaag agattagaac aaatagggat taaagctaaa
    18601 tcatttttac cgatttcacc ctttatctct acctattaca attatcgaga tcaccgaaaa
    18661 attgtcgtta ttgatgggga ggtatcattc actggaggta ttaatctagc agatgagtac
    18721 attaatgaag tagagcgttt tggccactgg aaagatgctg gtttaatgct tgagggtgaa
    18781 gcaacagaca gctttttaat tttgttttta caaatgtggt ctatcacaga aaaagaactg
    18841 attattgatc cttatctttc agatcattct ttaaaacttc cttcagatgg ctatgttatt
    18901 ccctacggtg attccccgct tgatactgat aaaataggta aaaatgttta tatagacatt
    18961 ttaaatcatg ctaaagagta cgtttatatc atgacacctt accttatttt agatagcgag
    19021 atggaacacg ctttacgatt tgcatcagaa cgtggagtag atatccgaat tattatgcca
    19081 ggagtgccag ataagggggt accatatgcc ttagctaaaa cctattataa agctttgatg
    19141 acttctggag taaaaattta cgagtatcaa ccagggttcg ttcattcaaa ggtatttatc
    19201 tctgataata caaaagcagt tgtcggaaca attaacttag actatcgtag cctttatcat
    19261 cattttgaat gcgcgactta tttatatcgt gtgtcagtta ttgctgatat tgtgaatgac
    19321 tttaatgaag ctcaaaagca atcactattg atgacatcag atcatttgac gcaacgtcct
    19381 tggtatcaaa aattgatagg attattagta cgaacaattg cccctctctt gtaattttcg
    19441 taaaatatgt tataatatct gtatgcgatg agtcgattgt gactgcaaag tcacttttgc
    19501 gcaggggagg tcattaaggc gggaagccga ctttgataat ctgtgtgaac cattttatca
    19561 caatcttatt tattaagaat gccccttgga ttgagatatt ctcaatcctt tttttaattt
    19621 tattatctta gttaaaattt agaatgtatc agtgattact gtgtttcaaa ataagaaagt
    19681 agtttttcgg gtatgagtgc tatgacttga caaatgctaa taacatttgc ataatgtaag
    19741 tagagatgaa aacttatgaa aagagatgat cttatgcaaa ttattaagcg tgatggccac
    19801 gttgctgatt ttgatccaga taaaatttat caagcaatta ttaaagcagc aaggacggtc
    19861 tatgttattg atgacacgtg gcgacaaaac ttaacacatg tcactaaaaa agtagttatt
    19921 gatttagaag aagcacatgt agaacgtcct actatcaata tggtccaatc ccttgtggag
    19981 aatcgtttga tggatgctgg atatattacc attgcagaac attacatttc ttatcgtctt
    20041 cagcgagatt tagagcgcaa tggctatggt gataagattg tggttcactt gcgttttgaa
    20101 caaataaaat aaaaacgctt ctaatggcat tttagtgtct ttgaggggat aaggtttaaa
    20161 tacctaacag ataaaaatct gttaggtatt tttttgctac tattaggtgt attctatatc
    20221 acatagaact taagcattca agctttaatt taactttctg tttatttttt gctacatttt
    20281 gggaaactcc cctcctttct tagttgaggt gaataaactt ttatttgata aatcatattt
    20341 ttaagtaatc taaaattatg tttttttaat ttcaaaatca tgctttcgtt tgttataaaa
    20401 accgatcttc catagttaga ttttttatcc aggcaattga agattggggc aactattcaa
    20461 ttagagattt tataatactt atttatcccc attttttata ttaatggtac gaagaaaagt
    20521 tagttgctct ttccacaagt atttttgatt agcgagttta atttgctttg tatttgttga
    20581 ttgatagcaa tagagagata gcgctttttt ccagttatta ttattctatc agatttatct
    20641 aatgtaaagt ttctataaga gtctgatgtc gtgtaatcaa tcactaaatg agtaggggtt
    20701 agttgatagt gaatatcagg gcaattttgt tttaaaaaga gagccaattg acgttcccgc
    20761 tgttttagat aacgcttaat aaagcgaaga tttttttgaa acatcccatt ttctaaataa
    20821 agagctaatg ctttttgcat tagtaagttc gtgtctaaat caatcaatga tttttgggtt
    20881 aaaaaatgag gttttaaacc tgacggtaaa actagagctc cgatacggag tgcaggaaaa
    20941 acactcattg aaaaagattt tagatagatg attcggtgat gagtgtcata ataatgaatt
    21001 ggtggctctt taagtttcac aaaatctcct aaataatcat cttctaaaat ataaacctgg
    21061 tatcgttgtg ctagacgaac aatagcttcc ttttccttag tgttataaga aagtcccaga
    21121 ggatgtgaaa atcgtgaaat cgtgtaaaaa aatttaatat cgccagtttg aaataaagat
    21181 tctaagagtt ctaaatcaag gccattaaag tgtctagaga tagtttgata gggtaatcct
    21241 aactgagcaa caatagcttc catccgatga taagtaggct tttcaaggag aattgttttg
    21301 cccgcattag gaaaaggcat ttgtgataaa atataaagcg cttgttgcgt cccagaggtg
    21361 attaatagtt ggtctttgtt actgtaaaca ctattttcag ctaagtaaag aagcaaagct
    21421 tcccttagtt cttctagtcc ttcggttttg tgataataat gaaagaggta tttgtcttta
    21481 gcacttaaag cctcatttaa gcagagtcgg aaatcttcat aagccatatt attataatct
    21541 tcaagactta gattaagaac attatcgggt atgcttacgt tacccaaaac ataataacca
    21601 cttttaggaa cagcataaat taagtgacga tattttaatt ctaaaagagc ccgctgaaca
    21661 gtatctttgc tacaatgata aaccttactt aataccctaa ttgaaggtag cttgtcccct
    21721 ttttttagtc gctgtttctg gatatcttgt tcgatattgg aaatgattgt ttgatatttt
    21781 gttgtcataa attgtcccca tacagttaag tgttataact attgtatctt atgcctcttt
    21841 ttcttacaat agttattata gaaaagaggt aatagctatg aaacggatta ttgtggcaaa
    21901 tgatctggtt ggtgttggta aggtagcttt gtctgctagt attcctttaa tggcttcttg
    21961 tttgttagag caagttttat taccaacttg ccttttatca agccatactg gcggaggaca
    22021 gagccctgtg aagcatacta catcaagtat attagacgtt tttttaacag attgggacaa
    22081 caaaagaatt aagtttgacg gcatttttat aggttatttt acgacaacaa gagatgggca
    22141 aaagctgcta gaatggcttt caagaaagca acttccctta attttagatc caattatggc
    22201 agataatgga aaactttatc aaggcttcag tcaaaaacat atagagatta tgataaaact
    22261 tactcaaaaa gctgagcttg ttttacctaa tattagtgag gcttgtctat taacacaaac
    22321 agcttattta gcaaaaaatt atgatgaaga agatattaga caggtggcta gaaaattagc
    22381 taagcttgga cctaaacagg ttgtcattag cggaatctct tttgaggagg gcagcattgg
    22441 ttttgcttac tatcagtcag attcagatca attaacattc cattttggga agcaattccc
    22501 ttaccatttc tatggtacag gagatatagc atcagctatt ataacagcag gattctatta
    22561 tcagctacca ctaacacaaa ttctagatct tgttgtttca tttcttgaaa aagtattgca
    22621 aaataccctt acattaaaaa gagatttaat cttaggtgtt gcttatgaat ctcatttaaa
    22681 ttacttaact aaatcgttta aaaagttgtt ggaggaaaaa aatgtcatct caaaaattag
    22741 ctaattatat tgaattgagt atgtatgccg ctttaatttt tatttcagta caagtgttgc
    22801 gtgtccctgt cggtatgcag tttattcatc ttggcaatgc attagttgtt attgcagtct
    22861 taatctatgg tagtaaaaaa ggagctctag ttgctagtct tggtttaggg atctttgatg
    22921 ttttgaacgg ctatgcttca gtcgtttgga taactatctt agaatccttg gctatttgtt
    22981 taattttgca tttggtatat gaaagagcta tgcaatctag taaaaaacca aaagccatta
    23041 taacaataac agttattgct gcattgtcaa aattaactat taaccttata aaatacttac
    23101 tgttagctta tataggtact cagctaccac tttcggtatc tttttgggta gctcttggaa
    23161 aaattggtgg tagtttcgga acatcttttg tgactttagt tgctgttcct cttttgtatc
    23221 ctgttatcaa aaacttaaaa gaaaaggtta caatcggaca agcaaaaaga ggtttttgat
    23281 acaagtacct tatcgataaa aaagcaaggt acacttttag tcaaatattg acaaaaggtt
    23341 acaattttgc cataatgaaa taactataaa gccgttttga cggctttttt gatgacagtt
    23401 aaggaagaaa cgatgagtat tttagaagtt aagcagttga gtcacggttt tggggatcgg
    23461 gctatttttg aaaatgtgtc atttcgcctc ttaaaaggcg aacatattgg actagttggg
    23521 gcaaatggtg aaggaaaatc aacctttatg agtatagtca caggacattt acagcctgac
    23581 gaaggaaaag tagagtggtc gaagtatgtc actgcaggtc acctggatca acatacagtg
    23641 ttggaatcag gacaaaccgt tcgtgatgtc ttgcgaactg cttttgatga gttatttaag
    23701 accgagaatc gtattaatga gatttacgcg tcaatggcag atgataaagc tgatattgct
    23761 gttttgatgg aagaagtagg tgagcttcaa gatcgtttag aaagtcgtga tttctatact
    23821 ttggatgcta agattgatga agtagcgcgt gcgcttggtg ttatggattt tggaatggag
    23881 tcagatgtta catccttatc aggtgggcaa cgaacaaagg ttttattagc caaattacta
    23941 ttagaaaaac ctgatattct gctattagat gaaccaacta accatttgga tgctgagcat
    24001 attgaatggt taaaacgcta tttacaacat tatgaaaatg cttttgtgtt gatttcgcat
    24061 gatatttctt tcttaaatga tgtgattaat attgtttatc atgttgaaaa tcaaagttta
    24121 gttcgctata ctggggatta ttaccaattt caagctgttt atgagatgaa acaatctcaa
    24181 cttgaagcag cctatgaacg tcaacaaaaa gagattgcta acttgcagga ttttgtcaac
    24241 cgaaataagg ctcgggtagc gacacgtaac atggcaatgt ctcgccaaaa aaaacttgat
    24301 aagatggata taattgaact tcaagctgag aaaccaaaac caaattttga atttaagcaa
    24361 gctagaactc ccagtcgatt catttttcaa acaaaaaatc ttgtgattgg ttatgattac
    24421 ccattgacca aagaaccctt aaatataacg tttgaaagaa accaaaaaat tgctattgtt
    24481 ggggccaacg gtattggaaa atctactttg ctaaaaagtt tattaggtgt tatcgagcct
    24541 ttagaaggtc atattgtcac aggggatttt ttagaagttg gctactttga acaagaagtg
    24601 acaggtgtta accgacaaac tccgctagaa gtagtttggg atgcttttcc tgccttaaat
    24661 caggcagaag ttcgagcggc actagctcgt tgcggactaa catcaaaaca tattgaaagt
    24721 caaattcaag tactttcggg tggtgaacaa gcaaaagttc gtttttgttt gttgatgaat
    24781 cgtgaaaata acgtgcttat tttagacgaa ccaacaaatc atcttgatat tgatgctaaa
    24841 aatgagctca aacgtgcttt aaaagcatat aagggttcta ttttaatggt ttgtcatgaa
    24901 cctgatttct acaatgggtg ggtaaccgat acttgggatt ttagtaagtt aacctaaact
    24961 attccttaat tttttacaca gaaattacta aaatcagtaa agatatagaa taaatactgc
    25021 tagatatgtg atggtttagg taactgatca ccaaccaaaa aagatgtgac tacatctttt
    25081 tttatctaat ggaatggtgt aaagtcgttt aataatagct tattttttga tgatcagttg
    25141 ttcatgaaat tgttggtgat taacaagtca t
//
LOCUS       DAUGUF010000029        24429 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUGUF010000029 DAUGUF010000000
VERSION     DAUGUF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24429
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.029"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..206
                     /locus_tag="VIB71_001266"
     CDS             <1..206
                     /locus_tag="VIB71_001266"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8823001.1"
                     /translation="TLKIHPNSLYRWIQEYEKYGESAFPGHGSALRHAQFETKKLEKE
                     HKLLQEELALLKKFQVFLKPNRK"
     gene            155..808
                     /locus_tag="VIB71_001267"
     CDS             155..808
                     /locus_tag="VIB71_001267"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8823002.1"
                     /translation="MSSSKKVPGLFEAKPEIKFQFLKENSVSLNSHHACQTLQVSRSG
                     FYAYLKRRPSSRHVENEALKEMIKAIFYEHKERYGSVRITQELCRRGIHVNYKRVGRL
                     LHQLGLYAKGSRYQYKYYNRRRSSLTRPNLVNQCFQATGKNKLWLGDLTYIPTQEGIL
                     YVSVFIDVYSRKIVGWAMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGA"
     gene            848..1063
                     /locus_tag="VIB71_001268"
     CDS             848..1063
                     /locus_tag="VIB71_001268"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8823003.1"
                     /translation="MSRKGNPYDNALMESFYKTLKRELVNDAHFATIEQAQLEIFKYS
                     ETYYNPKRLHSALGYLSPVEFEKIVTH"
     gene            1190..1345
                     /locus_tag="VIB71_001269"
                     /pseudo
     CDS             1190..1345
                     /locus_tag="VIB71_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039767.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1392..1922)
                     /locus_tag="VIB71_001270"
     CDS             complement(1392..1922)
                     /locus_tag="VIB71_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEQ8823004.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(1915..3249)
                     /locus_tag="VIB71_001271"
     CDS             complement(1915..3249)
                     /locus_tag="VIB71_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HEQ8823005.1"
                     /translation="MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNIL
                     LDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTA
                     LSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYK
                     QIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVE
                     DIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKL
                     LGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKS
                     IDFWHKTGGGLAEETINELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTT
                     KDIPSWKRMCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE"
     gene            complement(3471..3770)
                     /locus_tag="VIB71_001272"
     CDS             complement(3471..3770)
                     /locus_tag="VIB71_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823006.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(3926..4393)
                     /gene="perR"
                     /locus_tag="VIB71_001273"
     CDS             complement(3926..4393)
                     /gene="perR"
                     /locus_tag="VIB71_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEQ8823007.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(4445..4900)
                     /locus_tag="VIB71_001274"
     CDS             complement(4445..4900)
                     /locus_tag="VIB71_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEQ8823008.1"
                     /translation="MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNL"
     gene            complement(5087..7729)
                     /gene="polA"
                     /locus_tag="VIB71_001275"
     CDS             complement(5087..7729)
                     /gene="polA"
                     /locus_tag="VIB71_001275"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEQ8823009.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVRPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFSYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKTSKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQSKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(7860..9587)
                     /locus_tag="VIB71_001276"
     CDS             complement(7860..9587)
                     /locus_tag="VIB71_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEQ8823010.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMTMASGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAKKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(9603..10799)
                     /locus_tag="VIB71_001277"
     CDS             complement(9603..10799)
                     /locus_tag="VIB71_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8823011.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(11287..12378)
                     /gene="ulaG"
                     /locus_tag="VIB71_001278"
     CDS             complement(11287..12378)
                     /gene="ulaG"
                     /locus_tag="VIB71_001278"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEQ8823012.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(12631..14277)
                     /locus_tag="VIB71_001279"
     CDS             complement(12631..14277)
                     /locus_tag="VIB71_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEQ8823013.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(14602..15306)
                     /locus_tag="VIB71_001280"
     CDS             complement(14602..15306)
                     /locus_tag="VIB71_001280"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEQ8823014.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVARMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(15308..16171)
                     /locus_tag="VIB71_001281"
     CDS             complement(15308..16171)
                     /locus_tag="VIB71_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEQ8823015.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPAIEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(16176..16838)
                     /locus_tag="VIB71_001282"
     CDS             complement(16176..16838)
                     /locus_tag="VIB71_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEQ8823016.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     MKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(16929..17414)
                     /locus_tag="VIB71_001283"
     CDS             complement(16929..17414)
                     /locus_tag="VIB71_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8823017.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            complement(17537..17815)
                     /locus_tag="VIB71_001284"
     CDS             complement(17537..17815)
                     /locus_tag="VIB71_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ8823018.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(17886..19319)
                     /locus_tag="VIB71_001285"
     CDS             complement(17886..19319)
                     /locus_tag="VIB71_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ8823019.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(19626..22127)
                     /locus_tag="VIB71_001286"
     CDS             complement(19626..22127)
                     /locus_tag="VIB71_001286"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEQ8823020.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTSDQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASA
                     IAKMVEWLEAEGVGNENVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(22338..23477)
                     /locus_tag="VIB71_001287"
     CDS             complement(22338..23477)
                     /locus_tag="VIB71_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEQ8823021.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELAQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMSFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
BASE COUNT         7324 a         5300 c         4526 g         7279 t
ORIGIN      
        1 caactttaaa aattcatccc aatagtcttt atcgatggat tcaagaatat gaaaaatatg
       61 gagaaagtgc gttcccagga catgggagcg cacttcgtca tgctcaattt gagacaaaaa
      121 aacttgaaaa agagcacaaa ctgctacagg aggaattagc tcttctaaaa aagttccagg
      181 tctttttgaa gccaaaccgg aaataaaatt tcagtttctg aaggaaaata gtgttagctt
      241 gaatagtcat cacgcttgtc aaactcttca agtctcccgt tcaggtttct atgcttattt
      301 aaaacgtcgt ccctcttcaa ggcatgttga gaatgaagct ttgaaggaaa tgattaaagc
      361 cattttctat gaacataaag agcgttacgg aagtgtacga attacccaag aactttgtag
      421 acgtggcatc catgtcaatt ataaacgtgt tggtagactc cttcatcagc taggtctcta
      481 tgctaaagga agtcgatatc aatataaata ctataaccgt cgacgttctt cattaactcg
      541 tcccaatctt gttaatcaat gtttccaagc gactggtaag aataaattat ggctaggaga
      601 cctaacctac attcctacac aagaaggaat actttatgtg tctgtcttta tagacgttta
      661 tagtagaaag attgttggtt gggcaatggg ccgacgtatg caagacaagt tggtaacaga
      721 agctttcaat caagcttata atagagaaaa gcctaaagaa ggggtaatcg tccatacaga
      781 tcagggttct caatataccg gagcatgatt tcaggaccta cttagacaga aaaaatgtaa
      841 gtccaggatg agtcgaaaag gtaatccata cgataatgca ctcatggaat ccttttataa
      901 aacattaaaa agagagcttg tcaatgatgc tcatttcgca actattgagc aagctcagct
      961 tgagattttt aaatatagtg agacttacta taaccctaaa cgtctgcatt cagctttagg
     1021 gtatctctca cctgttgaat ttgaaaaaat agttactcat tagcttaact ttatgtctat
     1081 tttttcttga caagtccagg gtatgaagtc cctttataca catactttca aaacagctct
     1141 caatcctctg tccgctacaa aaatacgtca ccgctgccct ccagctgcct cattcaacga
     1201 caaacttgaa gccacaaaca gactcatcaa gggcattaag tacaatgcct ttagatttca
     1261 gaactttgac aactttaaaa ccaaaatcct catcgctttg aacatccaaa aagagagaac
     1321 caatctgatt ctctctcgtt gttaatgata agtcacccac tacagttgac aatgagtctc
     1381 ttacttcctg tttactcatt taatagctct tctggttccc aagattgatt aaactcatgg
     1441 tccttaaaaa gagaagccaa tcctgttatt tgtttcagtc ttaaaatttc atctttatcc
     1501 attcctaaat gttttgcaat ccagttatca cttcgcccac actcatgaag atcctttaca
     1561 atctgactca tcaaatcaac atcatgactt cctctagctc tattatgtcg aatggtagaa
     1621 gccattcgat agtctaatga cttatcaata acagaaacag gtaatctccc actttccctt
     1681 tcataaatat ctgaataatc tagcattata cgatatctat gaaaaccatc aacaatacta
     1741 taccgatcct cttccttatc gtaatagcaa acaatcggca tagtataacc atcagatttt
     1801 atactatcat acaataattt catttcaggc ggagcaactg aattcggatt ataatcattt
     1861 ggagaaatct tttcaattgg aattgattta atctcataga ctggactaat aaaattactc
     1921 actttctaac tcctttaaac tcgtcttata tttctctttt aaaaaggcta ctattttttg
     1981 ttgctctctt gtcaaaccaa accccatagt tcgacaaata tgatcgtttt ttaaaataca
     2041 gaaacacatt cgtttccagc ttggtatatc ctttgttgtt acaatatcgt ctgtatcatc
     2101 aggaatttga tctaaaaaaa taacccttga atgtttaaaa gaggtataat ttgaaatacc
     2161 atttctagca atacgatatc ctttttcaat tagttcatta attgtttcct ccgcaagtcc
     2221 tccgcctgtt ttatgccaaa agtctattga tttattaaat tttctaacat aattatttct
     2281 taacctcact ggtagcgttg ataaaagaaa ctgagtgtac gacttccacg aatgaccctt
     2341 tggtaaagca attgatttat atcccattgc tttagtacgt ccataaatat tcgaaaagtt
     2401 aactccttga acacgtccca aaagctttac ccaagtttct tgatctatta ttctataaag
     2461 atttaggcta tcaacagcat agtcttgaaa aggagatgca actctcattt gtgatggttt
     2521 taaacccgct ttatagaata gatcataaag ttcgttataa gaataagaaa acttatagta
     2581 agcatgccat atgtcttcca ctgaccaatc atataaggga gatgctgtcc agacatcttt
     2641 gaattgtttg gtaatccagc attccttttg ataaccatac tttttattga taaaaccact
     2701 atatctgtgt aaggattctg aagcacggtt tcctaatata caaactgttt tttgatttcc
     2761 gtgaatttgt ttataccacc taccaaattg tttcgctaaa tcctcctgat tcattttata
     2821 acgataagta gtaattgaat tattttccaa attaataaca taatcttgag atggcattgg
     2881 tcttacccag atatcttctg ttttgtcatc ccacggatac caaaacattt cataactact
     2941 aagtgcagtt ctagtagcca tcggtaagca cacccaatac aaagaaactt tttttctacc
     3001 ttctaaagaa gtgaatgttt cttgaacata ttttgttgtt aaactgtact gtgcttcaaa
     3061 atcttgatga aacacaccta tttctctatc cggataatat ttatctctaa aatccagtaa
     3121 aatattaaga agtaacccac tatcttttcc acctgagaag gaaatataga caataggaaa
     3181 ttcattaaac aaaaaatgta atctttctat caatgcatca taaacatttt gatttaaata
     3241 ctttttcact aaacttcctc attatgcatt taaaaatatt aatacataga ttcactaaga
     3301 atctcttttt cgagcttttt gttttttaat ttttcaagtt gaataattaa accttgcttt
     3361 tctttttcaa ggtaatagac tctactcctt gtaagtctaa cttattctta atcttattta
     3421 tcgctcattt tttaaattcc gatgctctca cagatattat cattgtttag ttacatgtct
     3481 gtcaatctat tcgccaccac actaggggcc atctgattga aaaataaaat ttcggagtcc
     3541 attgtttgct caagaatcat atctgtcaca attacgtcat actctgaaga cagtgacacc
     3601 atatcaacca tggtcagcct caagtcatca aagttgataa tctcaaaaaa tcctccaaaa
     3661 tactctttta agaagttgcc aacattgtta taacttctct caaccactaa tagtttcaag
     3721 cgacgacgcg attgatttgt aagaaagaga ttttcccagg tgaggaacaa acaaatagag
     3781 gagatgattg atggttcttt cctttaattc cttatgatcc ccagcaaata actctttaac
     3841 ataagcaaca aaggtctggt attgaactgg ggtttttgat ttgtaaaggc actatattta
     3901 taatgccttt atttaagggt taactctaaa aatcagattg gtcttttgct tggcaatccg
     3961 gacaaatccc gtaagcaata actgggatac gcgtgacctt ataacctgtt tgctcatggg
     4021 cttctttggc aatatccata acatcaacat ccataaagtc agcaatcttc ccacatattt
     4081 cacaaactac attgacgtgt tgatggccca taaagtcata gtaggtggtt aaatcattgc
     4141 tgattttcaa ctctgagaca aaaccttcat caactaaaac tttcaaatta ttatagactg
     4201 tggcaaggct catgttagga aagttaggct gtaagtcacg gtaaatctta tcggcactag
     4261 ggtgttctgt ggactgaatc atgtaagaaa taatggcttt acgtgtctct gtaattcgaa
     4321 tatgtttttc ccgtagatgc tctaggacat tttcataggc atctagggct tgctgatgtg
     4381 aatgaatgtc cataagctgc tactcctatc cttttttcct ttattatcac gcacgtctct
     4441 agtttcaaag atttgtgatg cattctggtt tagcgactaa ttgcaaatag tctattttta
     4501 ggcagcgatt catcacaata gcctctttgc ctgccgaccg taaaatggtt tgtacttctt
     4561 ggttttcaag gcctaattgc gcccaaaaga ctttggcctg acctgctaaa aagtctctgg
     4621 caacttctgg taaaaactca cttctgcgaa agacatctac aatgtcaacc tcaaagggaa
     4681 ttgccttgat actggcatag accttctctc ccaaaataag ctgacctgct aatttgggat
     4741 tgactggaat gatccgataa tccatagcct gcataaattt ggcgacacca taagctgctg
     4801 tgtctttgcg gtcagaaaga ccaacaaccg caatggtttt ggctgactcc aagtaagctt
     4861 ttaggatatc ctctgaggga ttttgaaacg aataaatcac ttgttcccct atctatttaa
     4921 taacctctac agctgttcaa tatagcagga taactcctaa agcatggctt caatcacttt
     4981 taaccttatc cgtcaaaaag ctcaaagcag cttcatgact tctcctacaa ttttttagtt
     5041 tattataaca taagttgtca aaatgagaaa taacaagtaa gaaaacttat ttggcttcgt
     5101 accagctctg cccagtactt tcatcgacac ataaaggaac agctaaatca acagcagctt
     5161 ccatggtgtc tttgacaagt ttttttatag cagtcaactc atcatttggc acttccaaaa
     5221 cgatttcatc atgcacttga agcagcattt tagctctaaa accacctgct tgcaaggcct
     5281 tatccagatt aatcatagcg attttgagaa tatcagctgc gcttccttga atgggcgagt
     5341 tgatggctgt acgctccgca aaagagcgaa cgttgaaatt acgagagttg atatccggta
     5401 attcacggcg acgcttaaag agggtctcta catagccctt gtctttagcc tcacgcacca
     5461 cattttccat ataggcttta atcccaggat agcgttcaaa ataggtatca atgtaagact
     5521 tggactgttt acgggtgata ccaaggttat ttgacaaacc aaaatcagaa atcccataca
     5581 caattccaaa gttaacagcc ttggcattac ggcggtcatt ggcagtaaca tctgctgcct
     5641 tgtcaatccc aaacacacgc atagccgttg aggtatgaat gtctgcccct tcattaaagg
     5701 cagcaatcaa atgctcatcc cctgaaatat gtgctagcac gcgcaattca atctgtgagt
     5761 aatctgaact caacaagacg gcatcttcat gagatggggt aaaggcctta cgaatcaaac
     5821 gcccctgttc caaacgaatg ggaatgtttt gaagattagg gtccacacta gacaaacgcc
     5881 ctgtctgggt gagatcctgc acatagcggg tatgaatctt gccatcagcc agaatataat
     5941 cctgtaaacc aatcacatag gtggattgca atttagtaat ctggcggtaa tccaaaattt
     6001 tagccacaat tggagcaatc ggtgccaaac gttccaaaac atcaacagct gtagaataac
     6061 ctgttttggt cttcttagtc atctcaagag gtagttgcat cttctcaaac aagatactgc
     6121 ccagctgttt aggcgaatta atgttaaatt cttggccagc catatcataa atctcttggg
     6181 tgagcgcttc aataatgacc ttgttttgct ctgccatatc ttgcaaagtc gccctattaa
     6241 ccttgatccc ttcaatttcc attttagcaa ggacattagc caaaggcaat tcaatattct
     6301 gatagaggtc tagttgctca tgggcagtga gcttgtctag catttgagac ttgctatcta
     6361 ataatacttt gaccttacga gctaagtgtt ctagtaagac gtctttatca ggaacagccc
     6421 gtttagcacc tttaccatag accgtatcgt cttcttccaa agagatgtca gtaaaaatgc
     6481 gggcaatggt gctaagctca ttgtcttcta cagttgacag aaggtaatta gctagtctag
     6541 catcatagct aggtgctacc aactcaattc ctaagtggct caacaagacc ttgctacgtt
     6601 taaaatcata agtggcaatg ggtttttgga agacctgctt aaaactatcc gtcgctaata
     6661 ggctaaggtc tgtggatgcg taaatctgct caccatgtcc ccaagcaaaa ccaatgatgg
     6721 cctcacgatg gtaattatcc cgaagcgttt caaagtagaa gatgtcttct gcgctaaaca
     6781 aatcagcaga cacattggtc acttcttgat aggaaatgac agctactggc tcttgaggca
     6841 tctggctagc aagacctttc ttgagttgca caaaatccat ctcatcgtaa aattgagaga
     6901 ggctagcaac atctggacca ttgtagacaa tatcatctaa gccaattgtg ataggagatg
     6961 ctgtattgat agtggcgagc gttttagata ggaaagcttg gtcacggtca ttgatcaagt
     7021 tttctttcat ttttgaggtc ttgaatccat caatatgctc gtaaatgcct tccaaactac
     7081 caaattcatg aaggagctta aggcctgttt tttctccaat ttttgtcact ccaggaatgt
     7141 tatccgattt atctcccatc aaggctttga ggtcaataaa ctggtttggc gtcaagccca
     7201 ttttttccat gaggtaagcc ggtgtgaatt cttcaaattc ggcaacccct tttttagaaa
     7261 tttcaaccac ggtattttcg tcagttaact ggatcaaatc tttatcacca ctgacaatgg
     7321 tcacatcaaa aggcacttct gtgcgctccg ccattttatc aagcgtcccg ataatatcgt
     7381 ctgcttcgta gtgttccaac tcataataag caatcccaag ggctgtcaac atctcacgaa
     7441 tataagaaaa ctgctcacga aattcatctg gggttttagc gcgacccgcc ttataatcgg
     7501 catacatttc tgttcggaag gtggttttgc ccgcatcaaa agccaccagc acgtgagtag
     7561 gccggactct tttcatcatg tggtctagca tcaaatgaaa gccataaatg gcattggtat
     7621 ggagaccgct atgattttta aagcggtcaa tttgattgta aagggcaaaa aaggcacgaa
     7681 aggcaacaga ggagccatca attaatagta atttattctt gttttccata gccttattat
     7741 aacacagagg gacgggcttt tctcctttaa gccattggtt ttgctgataa gtaaatggtt
     7801 aacctaaaaa gcctaggaaa attcctagac ttctgtattt gctatttaga caaaagcact
     7861 tattttgtcc aacttgatac tttagatttg tttgcctcta cccatttttt ggcggcagct
     7921 tctggactca tgcctttatt gatgtcaagc atgactgctt ccatatcttt ttgggtccag
     7981 tggaacttat caatgatttt gtagacattt ggaagatctt ttttcaagcc tttacgagca
     8041 atggtattga tgttctcagt cgagccaaag gtttctttag gatctttaag gtacttcaag
     8101 tcatacttgg caaacatcca gtgtggtgac caagctgtca cgacaatagg atcttttttc
     8161 ttgatcgctt gatccaagga agtcgtcatg gctcctgttg atgccgccac taactcccaa
     8221 ctagatagat tatgatactc ttttagagtc tttttggctg ctgccatgat acctgcacct
     8281 ggttcgatcc ctgtgatttt ttgatcggct tgtttgctta aatcctcaat actattaaca
     8341 tctgtcatgt atttaggaac agctaaacca agtttggtcc cttttaggtt aggtcctaaa
     8401 tcatctaatt ttgacttgta tttctgatat tgttggccat gggtgactgg caaccaagca
     8461 ctagttgaaa aatcagcgtt cccatttgca acggtttgcc acatgacagc attgtcaagc
     8521 ggtgtcaagg ttacatggta accttcgttt ttcaaaactt ctgcaatcac atgagttgag
     8581 gcaacctcag aatcccactg cacgtaagcg atgttaacag tttcaccctt atctgccata
     8641 ccagaagcca tagtcataat accgcgtcct aaagcagcta tcaaaaagac agcaagggct
     8701 gctagaccaa tccatttatt ggttttgcca gctttggctt tttcttgagg tttgctattg
     8761 aacaactgtg tcatacggtc aagaacaatc gccaagataa ccaaggcaag accactgaca
     8821 aatccactac caatatcagc gtgttgaagg gctgacaaga cttcacgtcc taaaccagga
     8881 gcaccaatca tggagcctgt tactaccatg gaaagggcta acatcatggt ctgattaaca
     8941 cctgccataa tagtattttt agctaaaggc aattcaactt taaagagctt ttgtttccca
     9001 gttgacccaa aggcatctga ggcctcaatc aattctgttg gaatgtcacg aatggccaaa
     9061 tttgtaaaac gaactgttgg gggcaaggca aagatgactg aagcaaatac tccaggcacc
     9121 ataccaatac caaaaaaggc aacggcagga atcaagtaaa caaaagccgg catggtttgc
     9181 ataaagtcca aaataggatt cacaatctga cggacagtgg catttttagc catccaaatc
     9241 cccagcggaa taccaataag taccgaaatc aaactagcta ctaacaccag agtaaaggta
     9301 ttcattagct gcttccataa cccttgattg taaataaaga gcaatcctaa caaggtaaag
     9361 gttggcaaag gccatttttt cttagcaagg aaaaacatcc ctgctgttac tagaacaata
     9421 aaaagtaacg ggtggataaa taaaagtgtt ttggtcatcc aatccatcaa aaagctacca
     9481 actacttgca taatatcaaa tagacctgag aaagttttag ttagccactc cgttagctgc
     9541 tccaccagtt gagctactgg taattttgtt tgtaatatcg tttccaaaat gcatcactcc
     9601 ttttagttaa ggtcttcgtc tgagatatta gccaaggctt caatcactcg tcctcgaata
     9661 atgacaccta acagacgatt attatcatct gtcactgcaa tcggagcaga tgaatcatag
     9721 ataagaggca aaatatctgt aataatagta tcttttgaga cagttctcac atcgcgatca
     9781 atcacttctg atagcggtaa cccttttttg cgcgcctcta tagcggcatc ggccgtcaaa
     9841 ctgccgacta attggcggcg gcgattcgtc gccatcaaca tagatacctc ttcgttgtgc
     9901 atacggttca aggcaacttg aggtccatct aattcaacag tagttgttaa cggtttgatc
     9961 atgatatttt gtgctgtcaa gactttagaa cggtccacat cctcaacgaa ttcacgcaca
    10021 aagtcattgg ctgggttagt caagatttcc tcaccagtac caatttgcat aatttgtccg
    10081 tctttcatca aagcaatccg atcaccaatc cgcaaggctt cattcaagtc atgactgata
    10141 aagatgatgg tttgtttcat gctgtcttgc aaatcaagta attcatcttg catctcacga
    10201 cgaatcaaag gatcaagcgc tgagaatgcc tcgtccatta agagaatttt agggctatta
    10261 gctagcgcac gggctaggcc gacacgctgc tgcatcccac cagatagttg gtttgggtac
    10321 tggtctttaa aatctaatag gcctgaatta tcaagggctt tttctgccaa tcgctggcgt
    10381 tcttctttgg gaacgccacg taattccaaa ccaaattcgg tattttccaa aatggtttta
    10441 tgaggaaaga gggcaaagct ttggaaaacc atgttaatgt catggcggcg cacctcacgc
    10501 agctgatctg ctgacatggt tgagatgtct ttaccttcca gcaagataga tcctgctgaa
    10561 ggttcaatca aacgatttag catgcggaca agggttgatt tcccacttcc tgatagcccc
    10621 ataataacaa agatttcacc ttttttgacc tcaaaactag cgtcatagac acctacagta
    10681 gcgcctgttt tcttaaaaat ctcactctta tttttgccag tctttaccat ctcaagagct
    10741 gctttttgtt ttttgccaaa aattttactg agatgtttga cttctaaaat tgtttccatt
    10801 cgttttttct cctaggtaat cgtttatcat gtgaaataat gacatagctt tggcgaaata
    10861 ttagccaata tttaacaaag tagctctaca caattaataa acgtgtggtc acttttttac
    10921 ttaaaaaaag aatctgccga aacagaacat aactatatta tcacgtgtgg tcactttttg
    10981 tcaaggacaa taactcgatc tggtaatgcc acaatgatag gtgatcgctt tcattctttt
    11041 aggtatggtc ttttaaccag tacaattttt tatcacaact gatggctatt tctttgctga
    11101 ttaggctatt gttacattag aaatccttct tttacctata atatctcttt tgcggccatc
    11161 gtaaataacg accacggtga ctcttaaaca tttgctcatc tctccaaaaa aactcaccta
    11221 agacagtgtc ctatgaagcg agttagctta atcaggcact atcatcttag gtgagtaggg
    11281 tgttgcttat agtaaagctt taaattggat attagaatct tctaagaagc agtcatcaaa
    11341 tccacgagga tgatggtatt cgatacgatt ttggtcttgt ggataggtgt acttgccacc
    11401 aacctcccag ataaagggat ggaaatcgta ttggagacgt tctttgcgca ttttccacag
    11461 ttcaaggatt tcatctgttg atgccataaa gtttgaccaa atgtcataat gaactgggat
    11521 aacgacttta gcacggagat tttctgccat acgaagaagg tcaacagaag tcatcttgtc
    11581 ttgaattcca attgggtttt ccccatagtt atttaacaca acgtcaatat cataatcacg
    11641 tccatgttta gcaaagtagt tcgaaaaatg agaatccgca ccatgataga tggtaccacc
    11701 tggtgtttca aaaatatagt taacagcttt gcgagccatg tcatcatctg tgatagctaa
    11761 acctgctaaa tcaccatctt gagcatcagc tccttgtatt gggagagtta ccagacaggt
    11821 gcggtcaaac gactctacag cggtgatctt aatatctttg aattcaaagc tatcacctgg
    11881 ctttaagatc ataatacgat cttttggcac accccaattt ttccaaactt caccacattc
    11941 ataaggtcct acaaatttaa catgattaag ttttgggtta ttgataatgg ctgccgcagt
    12001 attgatatcg atgtggtcac tatgataatg agaaaccaaa taataatcca actcattaat
    12061 cataaatgga tcaatcacca ttggttgggc cctaagattg ggctgtaatt tacgagctcc
    12121 tgccatatta gccatttgat gtccacgaac catatcctta acttgcttgg tcgctttccc
    12181 acgatttgac cataagtcca tgacaacatt agcaccgcct ggtgtcttaa tccagatacc
    12241 acagtttcct aaccaccaca tcgcaaagtt gtcagctggc acgacttctt gctcgatttc
    12301 ttcatttaac catgttcccc attctggaaa cgtgttaagg atccatgatt cacgtgtaat
    12361 atcttgtact ttagtcatta gggtttcctc cgaatttgtt cttcgtttct atactttaag
    12421 tatagacttt cttgtcaatg ataaaaagac caagtgtcac acagatctgt gttcaaaagt
    12481 ggactgactt tttcattagc tcagtctaat actgtctcat tttgcacact gtatcttgca
    12541 tcaatactgt attcaaagct atattaaaaa cctcagttat atttttctat gtcatagaaa
    12601 actgaggtac tttgacgact taacacttac tcatagcagc tcgcgatgaa tgagtttttc
    12661 aattttagaa accaaggcat aacgatctga ttcatctttt acaacagctt caatagcttt
    12721 tgtgagctct gtagaaaagc gggagtgctc actcaagcgt ccttgctttg aaaagcgtat
    12781 caatttgatg atatcatcgt cacttaaaat agggttaaca ataagcatcg ggattttagt
    12841 ctttagcgta tctgtagtag caacaatcat atcgactgct aaaaggtcgt aaacactctg
    12901 atactgttct gtcgtaaaaa cagcttcaat ctgaccattt gctagatacc tttgacactg
    12961 tttgaacaat aacttttgaa tgcctatccc atcatctgaa acaataacga gtttggtctt
    13021 ttcttgctct gtattattgt gacgcagctc tcccccaaga tggatagtca agtaggcaat
    13081 atcatcgtct gtcaagctaa tcgtccaatc ttgttccaaa atagtggcac aagattgagt
    13141 catagcaaac aattcttcgt atttttcttt aatatggtct gttaagggat taactaaaaa
    13201 aatcccataa gctttacggt aaacgagcgc cttacagtgg gtcgtcaact gcttcagcaa
    13261 atcctgttta tgcgtgaaat gtaactgata acggctctcc aactggtcaa taaagtgact
    13321 aatggttgct cgcatgtcgt cataatcttg actttccacg tgatgatctt gatcttttcg
    13381 aaaagacaac atcaacatcg ctaccatact aacttcgata tcatccaaat gaagcttaaa
    13441 attatggtaa agctctctag ctaaatcctg agcaatgtga tattctttac gtttccaaat
    13501 caaatgaaat tcttgtttaa gagcagactt tgtttctgaa tcaagacgca tattacgata
    13561 acttaaaagc atgaaaggta aaatctgcaa catgaattgg ctatcttggg tattaattgt
    13621 ctttcctaaa ctagcttgag ataaaaagag atactcatga aaataggtca aaatatcttt
    13681 agaaaaataa accgataagc cttgtatctc tgagagttta cggttgaata tatcaataaa
    13741 gctagtattg ccaccttggt aaacgtccac taacaatttg tacaggtatt gaataagagc
    13801 cattggatga caaccaaaat aatatcccct agcctttgtc gcatgaagct gaatcttgta
    13861 ttgtttgtct tccagttctt cccttaactc agtcaggtca tttaaaatcg tgttacgaga
    13921 cacatcattg atctgcatca gtttatcaat ggtcacgcgc tcagtggaaa ccgcaatata
    13981 aatcgaggat aggcgtctgc gctcatcact tttcatgaca taattataat cagtcacttc
    14041 ttctaataat aagcgacaag cagctttttg atcagctgtt aaaagaatgc caagtctagg
    14101 ataagagata atctgatcta ctccctttgg caaagcctga ttaattttgt caagctggta
    14161 ataaacttta cgacgtgact gatttaaagc atgagaaatg gccataactg tctcaggtgt
    14221 ttctagttta agtaaataag acagcaagtc ataactcttt ttatctaaaa tcatcatgtt
    14281 tacaaacctc ctctctgaaa atccatcctt gcttatttta tcatgatttc agtgactgcg
    14341 cagccaagtt ttgaaaaact caccataata agattcgctt aatatgattc gagctaatca
    14401 cctcaactga tccaacacca acaccttata tctggtctct aagaactcca caacatacga
    14461 ttcatccagt ttgtgctcat tggcgtttaa atagttcatc gaaaaggaca agtcaaaagg
    14521 acttgcccaa acaatgatta acaaaacctt gaactttctg gcttctagtg agaacctgtg
    14581 ctaataagcc atatcgtgac ctcatttttg accgtaataa gcatttgggc catgtttacg
    14641 caaataatgc ttatccataa tgtatcgtgg cgctggctct acgcgtggat tgatttgttc
    14701 tgtcaagcga ttcatcctag ccacttcttc taagacaacc gagtggtaaa cggcttgctc
    14761 tggggttttc ccccacgtaa atgggccatg attgcgaacc acgattcctg gaaccgccat
    14821 aggatctaag cctcgcttgc taaactcttc taaaatcacg ttgccagttt cttgctcgta
    14881 agccccatca acttctgctt ttgtgagaga acgagcacac ggaactggtc catagaagta
    14941 gtcagcatgc gtagtcccat aaaacggaat atcacgacct gcctgagccc aaccaacagc
    15001 ttctgtggag tgagtgtgga caataccgcc cacttctggc caagctttat aaagttccac
    15061 atgggttggc agatctgaag aagggttcaa atcaccttcg accacattcc catcaaggtc
    15121 tgtaacaacc atgttttctg gtgtcaagag gtcgtagtcc accccagaag gcttgatgac
    15181 aatacgtcct aattcacgac aaacttcaga gacattgccc cacgtaaatt tgacaagacc
    15241 gtgttgtggt agagacttgt tagccgcaca gacacgttca cgcatttctt gcaagttttt
    15301 cgccatatta tgccaacccc gctttctcaa taagtgggta aaggaagtcc tgagcttctt
    15361 tgatagcagc ttttgtttcc tccaccgtgt cacaattttc tgaccacatt tcaatcaaaa
    15421 aaggcccatt gtagttggtt ttcttgagga ccgcaaacag ctcttgccag tccacacaac
    15481 cttgaccaaa tggcacatca cgaaactgcc cttttgaggt ttccgtgaca gcataagtat
    15541 ctttcaagtg gagggctgca atggacttgt gaccattgta aaattcactc cacaaatcat
    15601 tatgccaggc agaaacattg cctgcatcag gataaacaaa gagataaggc gagtcaatct
    15661 ctttttcaac tgccaagtat ttttcaatag agttgataaa agggtcatcc ataatctcaa
    15721 tagaaagcat cacttgggct tcttcggccc agtcacaaga ttgtctcaag tttttgataa
    15781 aacgagcacg ggtttcaggc gatttttctt catagtaaac gtcataacca gctaattgaa
    15841 tggtacgaac gcctaagtcc tgtgccaatt caatacattg tttcatcagt ttaagggact
    15901 tggcttcaat agcaggatca tttgagccta gtgggtaacg tctatgacca gaaaaacaaa
    15961 tggtcgggat gcgaatgcct gtttcataaa tggctttcac taaatcaagc cgttcttcct
    16021 tagtccactc taagcgcgct aagcgagcat ctgattcatc aacagacatt tccacaaaat
    16081 caaaacctaa gtcttttgca aattgcaagc gttcacgcca ggtaaactgt tttggcgttg
    16141 ctttttcata aataccaata ggacgcgcca taaagttacc cccagatacg tttgatttca
    16201 tctttgaagg cacgcgccgc tgcagcagga tcttctgctt cagtaatgcc tcgccctgcg
    16261 ataaaggtaa agacatcaac cccttcaaaa agtttcaaag tgtctacatc aagcccacca
    16321 gttactgaca cgcggaagcc catgtcaatc aatgttttca ccttgttaag gtctttttca
    16381 ccccaagttt ctccagcaag aagggcatca cgtgattggt ggtaaatggc ttgggaaatc
    16441 ccagcgtcaa gccataattg agcttgctca taagtccaat caccataaag ttcgatttga
    16501 atttccccac ggtcaccgcg ctcttctttc atagccttga gggctgcttc catggttgga
    16561 atcgtcgcac agcaaatgca ggtcatccag tcagcaccac gttttgcatt gtttttagcg
    16621 accgtaccgc cagcgtcagc acatttggta tctgctacga taattttctc tgggaagagg
    16681 ctgcgtaata cctcaaccaa ctcgcttccg acttgaagca agcagaccgt accggcttcg
    16741 ataacgtcta cttcgtgacc cacagcaacg gctgctttaa cagccccctg taagtcagaa
    16801 tggtctaaag caacttgtaa atttggaata tgtgtcatct ctttttccta aaactcttag
    16861 ccaccgtgca aactggttaa gagttcttat cctttccatc attcgttagt atcctgtgta
    16921 aggaaagctt aagcattcaa gtccatacct tctaagtaag gactatcttt agattcttct
    16981 accatttcta gaacctcttt aggactttgg caggccacca agcgttcaat ggcgttatct
    17041 agttcaaaca aggccacaat ttgtgggata gccactgttg tgtgaataga agggtctgta
    17101 gcggccaacg tcaaaagaac agaaacctct ttaccatctg agaaggtaac tggttttgtt
    17161 agtgtaatca aagcaaatgc attgcgatta acgcctaaac ctgcttctgc atggggcata
    17221 gccatacctg gcatcaacac ataataaggg ccgtattttt ctgttgatgc aatgatggcg
    17281 tcgtagtaag ctgacgtcac tgctttgcta tcaatcaaag gttgaacagc taattgaaca
    17341 gcctcttgcc aagtatcagc acttagcccc aatcggatgg agttgttgtc aataaaggct
    17401 tgttttaaat tcataaaaac tatctctttc tagtgtcttg ctttgcaaca cacaccattt
    17461 ttactagttt tatcctacta aagagaaaga gctgaaaacc ttcgtcacaa ctccttcgtt
    17521 ttgattcaga attagcttat agcacttctt gtagtttggt tttaatttca ttatcatcca
    17581 tcaggttatc aagaccaacc aagtggcctt tggtacgacc atcaagctca tgaatcaagt
    17641 gatttgatgc cactacaata tcatagccag aagctagacc tttagcttca ccaactgagc
    17701 aagaagctga ctgaatatct gtcacgccaa gttgacgaag cgcattttca actttcattt
    17761 tgatcaccat agatgacccc ataccattgc cacatgctgt taagacttta accattgttt
    17821 tttcctccga aaatgtttta ttattgtttt gttaaaatag cagagctatt tcttaagatg
    17881 cagtgttatt gagcttcccc acggtaataa gcttctttgt ccttagcttt tgcgaattgc
    17941 aattgtggaa tggcaagtaa gaagatgcaa acaagcacat accctgcaat accaaggaat
    18001 ttgaagaggt acccaaatgg taaccatgga agaaccaagt cgatattacc gtgataacca
    18061 cctgtaagtc ctaaaagacc tacagcaaca gcaccaagtg caacttgcaa aatacctgaa
    18121 ataaatgata gagctaccgc tgctttccag ccaccacgtt tatctgcata aaccgcaatt
    18181 gccgcattat caaagaatac gggaacgaat cctgtgataa ttaagattgg atttttaaag
    18241 ataacaagaa gagcaatggt gattaattga ccaatcaaac caaaggcaaa tcctgaaagc
    18301 accgcatttg aagaaccaaa gccataggaa gctgcaacgt caaccgctgg gaatgaccct
    18361 ggaagcaatt tgcttgagat cccttgaaag gcattggtca attcagaaac aaacatgcga
    18421 acaccctgca tcaagataaa gagataaact gagaaggtga gagaggtttg caaaatatac
    18481 atgaagaaag cttgcttagc tgggttgaat gctccaggtc cgattaagtc cacatcagac
    18541 ataatgtctg gaccaaggac agccaagata gctccgaaaa agaccaacat caaagttgct
    18601 gacgcaacaa cagtatcatg gaaaatgttt aagaaggttg gtaattttag gttatcaagg
    18661 ttttcttctt ttttaccaaa gaacggtgca accttatcca caaaccaaat cgcaaattgt
    18721 tgttggtgac caatcgcaaa cccaccgcca cctgtaaggc gttgagttgc ttcaacggtc
    18781 atgtttgagc tgatagccca gtaaagccca cagatgatac cgactgccca tgccccaaaa
    18841 gcattttgga attgagggat taaaagaagg acaaagaccg aaatcgtcgc tgcctgttgg
    18901 accatgatgt gacctgtgat gaaaagggta cgaactttag tgaccttgcg aagtgcaacc
    18961 aaaagaatgt tgaccccaaa tccaatcaag agagctgtcg tagcaacact gatgaagccc
    19021 atctcttcta acttagtatt agcagcagcc aaaccaaaat aaggatcaat aacggcggct
    19081 ttcaattcaa atttcttggc aagagcaacc aagatcggac gaaaagtcgt tacaagaccg
    19141 cctgctccaa cgttcaaaat caagtaacca acggtagcct ttacaaaacc agcaaagacc
    19201 tcataaatgg gttttttaag gagtaaatac ccgattaaaa ccaaaagacc tacaaagaac
    19261 gctgggtttt gcaaaatatt ttgcgagaac cagtttaggg gagctaggag catttccata
    19321 agaactacct cttttcaaag ttaataaaga taaagtgttt atatgttcat tataggtaat
    19381 gaaagcgttt taaaaaagac caactatcac acaaagaagt gttcaatatt agacttaagt
    19441 taacttattt taaaatttaa ctacacttaa taataaggag aaaatcaccc taaacaacga
    19501 ttaaaaacca caagaacctt cgttcttgtg gtttttctag atgagttgct ttttgaatag
    19561 atcagctctt tggcattaac tgtgacgtga cgcaaataac cactgaaggg ctgtgtcacc
    19621 tcaaactatt tgataacaat attaacgagt ttgtttggta ctgcgatgac tttgatgatg
    19681 tctttgcctg cgatttcggc ttggactttt tcgttagcaa gggcaacttc ttgtaattct
    19741 tcgcgtgaaa ggtctttagc aactacaagt ttagctttga ccttaccttt gatttggaca
    19801 acgatttcca catcgttttc aaccaatttg ctttcatcat aacttggcca tggcacgtaa
    19861 gagattgact cacctgaggc tgtcaaggct tgccagagtt cctcacctaa gtgcggtgca
    19921 aatggtgcaa tcaattgaac aaagcctttg gcatagtcgc taaagagttt gtcttccttg
    19981 ttggctgcat tgacaaatac catgagttga gcgatagctg tgttgaattt catttggtca
    20041 acttgctcag taacggcctt aacggtttcg ttgtaaacct tgtcaagggc tccgctattt
    20101 tcctcagtga tctctttagt cgtgatcaaa cggtaaacac ggtccaagaa cttacgtgag
    20161 ccttcaagac cttcttcaga ccaagcgatg gaagcgtcaa gtggtcccat gaacatctcg
    20221 taaacacgaa gggtgtcagc accgtactgc tcaacaacat catctgggtt gacgacgttc
    20281 ttaagtgatt tagacatctt agctggtgct tgttcaagct cttccccagt ttccacatgg
    20341 aagaagctgc catcacgttt ttcaaccttg tcagtcgcta caagcgctcc acggctatcg
    20401 cggtagcttg tccccaaaat catcccttgg ttaaagagtt tttggaatgg ctctttggta
    20461 ggtacaacac cgagatcgta aagaaccttg tgccagaagc gagcgtagag aaggtgaagc
    20521 acggcatgct ctgcaccacc gacatagata tcaactggca accattgttt gaggagttcc
    20581 tcatcagcca gtttttcggt gttgtgtgga tcgatgtaac gaagataata ccagcttgaa
    20641 cctgcccatt gtggcatggt gttagtctca cgacgacctt taacaccatc ttcacgggta
    20701 acttccaacc agtctgtcac gttagcaagc gggctctcac cagtacctga aggacgaata
    20761 tccttagtta ctggaagaac caatggcaat tcactctcag gaaccgctgt tgatgtccca
    20821 tcttcccagt ggatgattgg gattggctca ccccagtaac gttgacggct aaagagccag
    20881 tcacggagac ggtaagtgac attttcatta ccgacgcctt ctgcttcaag ccattcgacc
    20941 attttggcaa tagctgacgc tttgtcaaga ccatctagga agtcggagtt gatgtgaaga
    21001 ccgtcttctg taaaggcagc ctcttcaaca ttaccacctt caagaacagg gatgatgtct
    21061 aggttaaatt gttttgcgaa ttcccagtca cgttcatcgt gggctggaac agccatgata
    21121 gcaccagtac cgtagctagc aaggacatag tccgcaatcc aaactggcat ttctttgccg
    21181 ttgaccgggt taatcgcata gctacccgtc cagacaccag ttttttcttt ggcaaggtct
    21241 gtacgagcaa ggtctgattt gagacttgct tgacgtttgt agtcagccac ggcttctgcc
    21301 tggtcagatg tcgtaatagc atcaaccaag gcatgctcag gagcaagaac ggcgtaagtt
    21361 gcaccaaaaa gcgtgtcagg acgtgttgta aagacagtga agtccttatc tgtatcctta
    21421 accttgaagg ttacattagc gccagttgat ttaccaatcc agttgcgttg catgtccttg
    21481 attgattctg gccagtcaac ttcttccaag tcttctagca agcgctctgc ataggcagtg
    21541 attttgagca tccattggcg catgggtttt ctgacaactg gatagccgcc acgttctgat
    21601 gtcccatctg gaagaacctc ttcgttggcg atagctgttc ccaattcttc aacccagtta
    21661 acgggaactt cagcttcgta ggctagacct ttttcataaa gcttggtaaa gatccactgc
    21721 gtccacttgt agtagttagg gtcagttgtg ttaacttcac ggtcccagtc gtatgagaag
    21781 ccaagagcat taatctggcg tttgaagtta gcgatgtttt cagctgtaaa ctcggctgga
    21841 tcattaccag tatccatagc gtactgctca gcaggaagtc caaaggcatc ccaacccatt
    21901 gggtggagga cattgtgacc ttgggcacgt ttgaaacggc taagaatatc agttgctgta
    21961 tagccttctg ggtgaccaac gtggagacca gctcctgatg gatatgggaa catatctagg
    22021 gcataaaact taggttttga tgcgtctgtt cctgttttaa aggtgtgatt atctgcccaa
    22081 aaggcttgcc atttgggttc aatagcggtg tgatcgtaaa atgtcatgtg aaatctccca
    22141 tgtaaaaaat ctagtcttct tattatagca tgagatgaag cttttaggaa tggtcaagac
    22201 atgactagca ccttggcttt tgagacttca gacgattagc tatttttaaa ccctgcttta
    22261 gcatcaacca tcctcacaaa aagctaataa aaaagccaga cttgctctgt aaacagagcc
    22321 aatctggaca aatagactta aaaagcaagt gcttgctcaa aatcggccaa taagtcttcg
    22381 atattttcaa caccacaaga caagcgcagc aaaccatcaa caaccccttg ttccaaccgc
    22441 gcttgtgacg ataaacaagc atgagacatc gttgctggat gtgacaaaat ggactctact
    22501 ccacctagac taacggctaa aatcggcaac tgaatacgat gggtaaagga catcagctcc
    22561 tccttagaag ccaactcaaa ggataaaaca gcaccaccat tcttagcttg ttgcaggtgg
    22621 gtatcgtgat taggatgact gtctaagcca gggtaatgta ccttaagaac tttggggtgc
    22681 ttcgctaaat agttagcgag ctgctgagca ttttttaccg cttgttccat acggatcccc
    22741 atagttttca tgccacgaag aatcagccaa gcgtcttcga ccccaacaat tgctccaaag
    22801 tttttttgaa aaagcttgag ctggttgtag atagcctcat tattggtagc agctaaacca
    22861 gctaccacat cactatgacc attgataaat ttggtcacac tttctactac aatatccaca
    22921 cccatagcta agggttcttg atacaaactg gtcataaagg tattatcagc cacagttagc
    22981 acaccataag ctttggcgag ttgcgcaagc tctgaaatat cacaaatttt caagagcgga
    23041 tttgacggtg tctctagata aatcatacgc gtattaggcc tgatacttgc ttttactgtt
    23101 gctaaatcag ccatatctac aaagcttgtt tcaatctgat aattgggtaa aatagctgtc
    23161 gcaaattgac aagtccctcc atagacctcc aatgggaaaa tcacatgatc tccagctttt
    23221 aagagcatca aaacagttga aatagcagcc ataccagatg cataagccac cgcataagtc
    23281 gctttttcta aacaggctaa cccgtcttct aaagcttcag tcgttgggtt tgaaaagcgt
    23341 gtgtacaaat gtttttgact aggacaatac agttctgaat tgtggaacgt cgaagtctga
    23401 tagatgggaa ctgaagctgc tcctgtaaac tcgtcaataa ccgtatagcc atgtaataag
    23461 gtcgtatttt ctctcatttc gtgcacctcc gcaatagcgt taactccaat gaactctctt
    23521 ttagacaatg gtcccacccc aatggttgca caaaccaaaa agctcttcaa aaaagcgtga
    23581 tctgctaacc tataagaaaa ataaagaaaa gtagtgggca ccttttaaat ggataatgaa
    23641 tttttccaat aatatcattt ttagatcgat tacgtttatt atacaacctt tagctaagtt
    23701 tgcaagccct tttatcatct ttgaccaagc tgccaacacc tctccagcaa gttaaagtat
    23761 agctaccttt ggccccatcg tctcaaaagc tcaaattatc acactgacag tcctaccttg
    23821 catcgtcacc tactcaatat ggcaatactg ccatcaaaat ttcattaaaa ggtcacaatt
    23881 tatttcattt aatgagaaac agaacttgtt ttcaccatgc gtcttatagt ataccgctaa
    23941 aatactattt atttttagga gagaaatata gtgaaaaaca aattattttt agttgccctt
    24001 gcgaccgtaa ctgtcctagg gccctcttta gcaacccctc atcatcagac cgtgcatgcg
    24061 gctgagcagg caaaagaacc ccaaaccagc tcaatgacgt gtactaacga tggatctgta
    24121 tgcgctggct ggcatagttt atcagaagga gacagtataa cttcaaattc atcttcaaac
    24181 accaagactt ccctgttaaa ctggttatgg agcttaataa caaatttgtg gaattctgca
    24241 aaaaacttgt tcatctaaga tctctataat catatccatg gaatttaaat aaccatctcg
    24301 tggcggtttt ctaatcctag gtcgccacac ttcttattca gataaataat aataaaaaca
    24361 ttaaaataac acttgattta ttaacaaaaa gttagtataa tataatcaca atacaaatta
    24421 aaggagtta
//
LOCUS       DAUGUF010000030        23939 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUGUF010000030 DAUGUF010000000
VERSION     DAUGUF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23939
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.030"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            348..830
                     /locus_tag="VIB71_001288"
     CDS             348..830
                     /locus_tag="VIB71_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEQ8823022.1"
                     /translation="MDWRWWKIAYEELTEKQQRFVDKYITTFNATESAKQAGYSEKSA
                     YSQGQRLLKNVEIQKAMKERFLEAKDTKGDRIQDVAETLEQDTSIARGEIQISEFKET
                     DMLTGQVVIHTKREYTPSHEEQGRARDRIYKVNGAYSEKRELEHSGTVVFANEDNIPD
                     "
     gene            808..2097
                     /locus_tag="VIB71_001289"
     CDS             808..2097
                     /locus_tag="VIB71_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ8823023.1"
                     /translation="MKTTSLIKVDLPSTIGIGYGAFWRSRNFYRVVKGSRGSKKSKTT
                     ALNFIVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNQLKVTHLFKFNESLPEITV
                     KATGQKILFRGLDDELKITSITVDVGALCWAWFEEAYQIETEDKFSTVVESIRGSLDA
                     PDFFKQITVTFNPWSERHWLKRVFFDEETKRADTFSGTTTFRVNEWLDDVDKRRYEDL
                     YKTNPRRARIVCDGEWGVAEGLVFDNFEVVDFDVEKTIQRVKETSAGMDFGFTQDPTT
                     LICVAVDLANKELWLYNEHYQKAMLTDHIVKMIRDKNLHRSYIAGDSAEKRLIAEIKS
                     KGVSGIVPSIKGKGSIMQGIQFMQGFKIYIHPSCEHTIEEFNTYTFKQDKEGNWLNEP
                     IDKNNHVIDAIRYALEKYHIRSNESNQFEVLRAGFGY"
     gene            2109..3611
                     /locus_tag="VIB71_001290"
     CDS             2109..3611
                     /locus_tag="VIB71_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ8823024.1"
                     /translation="MYTESFRDSTGKTKTLEFRFHREARMRYQAESLESLLTEKYKLL
                     REMIEHHDKVQKPRIQELLDYAEGNNHTISEIGRRKDDDMADVRAVHNYGKYISTLKQ
                     GYLVGNPIRVEYIDGTEQQQDLLKDLSVKNNFHQLNRRLVKDLSKVGRAFELIYRSMD
                     DKTEVVRLDPREVFVIYQNNLEQSSLAGVRYYNKNQLDGTTKIVELYTDNKILKFEYD
                     GDLTPIGETSSHAFGSVPITEYLNTDDGMGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPGYVDTAEKAIEYLRKMRKARLLNLEPPVDQDGREGSVDAKYLYKQY
                     DVQGTEAYKNRIVSDIHKFTNTPDMTDSKFAGQQSGEALKWKVFGLDQERVDMQALFE
                     QSLKRRYKLIARVSQLLKEIDDFDISKLKITFTPNLPKSLQEKIEAFKALGGELSQET
                     AMAITDIVEDAKKEISLINSESKSRSQLAQKLEETSRLTDRELAHDHQKE"
     gene            3592..5154
                     /locus_tag="VIB71_001291"
     CDS             3592..5154
                     /locus_tag="VIB71_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEQ8823025.1"
                     /translation="MTTRKSKYWRDRIKKEMDAKEADDISLEQSMKQLHDYHFRNIEK
                     EIESFYQRYADKEKIDLSEARKRASELDISAYQKKAKELVAKAEKLRKEGRTVTRDDF
                     THQENADMSIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKKFLDEGYRKETEFQA
                     GLLGLSVASQASVKSLADAVINANFKGAKWSDNIWDRQDKLRSIISQSVQSAILRGKN
                     GLTIARDIRREFDVSASYAKRLAITEHARVQMEVGRLSMAENGFAMFDILPEPKACDV
                     CKDIAKHGPYHLDKWIIGENSPPFHPYCRCAVVGLDKKQEEKVNDKSEKFENITPNLM
                     PLFSKFASKITDLQRKIVYSADLADTGYIRTPHAFDINNTLRNKGYNYLNVDDKLITD
                     TLDSVISINSTPKNIKVYRFDDFELLGSINEQNNNIFDSGNFMDKLNQGGLSYTNDGY
                     TSASYDVKKNVMGYRPIKTEIKVPKGSHVYLTDNEEESEIILPRGTKYDIINAKINEY
                     EEIEITMEIRKE"
     gene            5158..5343
                     /locus_tag="VIB71_001292"
     CDS             5158..5343
                     /locus_tag="VIB71_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823026.1"
                     /translation="MDFSDFLNKKQKEWDESHPIPDFSAMSDEELLYQPMSEALVSER
                     FAKELSKEVRKRNLLSK"
     gene            5729..5995
                     /locus_tag="VIB71_001293"
     CDS             5729..5995
                     /locus_tag="VIB71_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823027.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAKALRNQNRRIAELRAIIQ
                     QNTQAINREFVTAKNTILDNQLAIKSIGDDVNHIKQNYKRKWRK"
     gene            6139..6672
                     /locus_tag="VIB71_001294"
     CDS             6139..6672
                     /locus_tag="VIB71_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ8823028.1"
                     /translation="MAEETQVVETVEEQVVPEAKQPQDEKKYTDADVDAIIDKKFAKW
                     KSEQEAEKSEAKKMAKMNEKEKADYEKQKLLDELQELKNDKTRNELTAVARQMFAESE
                     INVNDDVLGLVVTLDAEQTKANVTTLANAFAKVIADDRKALVRQTTPSTGGGIAKQTN
                     YGANLASKAAQQSTKLF"
     gene            6682..7062
                     /locus_tag="VIB71_001295"
     CDS             6682..7062
                     /locus_tag="VIB71_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEQ8823029.1"
                     /translation="MNKRKVTTSKEILHNLDYEAISVTLDSNKIGKKVVPAGTILAGK
                     DKSIFEDRKQKVETVTNEEVSTKEYVDGILFTDVDLTNGDAVGSCVYRGTINADKLAD
                     SSVAENYDDLEEVLPHIVFIKGGK"
     gene            7065..8114
                     /locus_tag="VIB71_001296"
     CDS             7065..8114
                     /locus_tag="VIB71_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEQ8823030.1"
                     /translation="MALIHEIITSENIKGFYNAKNENVENTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEKMPFFKEAMSVKEADRQQLNILSQ
                     TKNNELIDTILASIYNDQATLIAGAKARLEAMRMEVLSKGKIHIQSNGVMKDIDYGLA
                     EDQTTKPDAKWDSAGTATPLKDIEKAIEKMAERGFVPEAIIMNSKTFSLIKNAESTLD
                     VVKPMAPNGAAVTKRDLNTYLEDELQIKVILKDGMFVGDDGESRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLLGGEATDANVSIVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVHIINGLQDA"
     gene            8126..8392
                     /locus_tag="VIB71_001297"
     CDS             8126..8392
                     /locus_tag="VIB71_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823031.1"
                     /translation="MAKVIKTFRDKVTTNAYYVGDDYKGDRIEELTANGYLAGNTPKL
                     DTVEEVDLDKLKSDEIKAKLDELGIEHDSKLKKAELLELLKANI"
     gene            8404..8757
                     /locus_tag="VIB71_001298"
     CDS             8404..8757
                     /locus_tag="VIB71_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ8823032.1"
                     /translation="MANVNTFSIVKNVKLDLGIEDDNQDQLLEMLLNRITDHFKANYG
                     VLEIDNAFSFVLEDCLIARFNRRGSERAKTEEVEGHKTTYYDHLNEFEPYDAMIMTKL
                     NLIKDKSRKGGLYFL"
     gene            8754..9062
                     /locus_tag="VIB71_001299"
     CDS             8754..9062
                     /locus_tag="VIB71_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823033.1"
                     /translation="MRYADRVTFVKTTDEQYNPDLGEYTHTEVISITKPCFVMDMGME
                     KSVQIFGDYQKDRKVIYLKQPYTKAFDYCEYEGRRYKTQANKLGAIVFYLEGDDSIGG
                     "
     gene            9043..9408
                     /locus_tag="VIB71_001300"
     CDS             9043..9408
                     /locus_tag="VIB71_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ8823034.1"
                     /translation="MTLLVADISLKVVGTAGLKKKLELIIKKDAVKKIVRDNGTQLQR
                     KMINKAVFTKGYSTGATRRSITMQIGDGGLSVKVKPGTHYAGYLERGTRLMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9405..9794
                     /locus_tag="VIB71_001301"
     CDS             9405..9794
                     /locus_tag="VIB71_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ8823035.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFTVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVELMLSVWGMQKKRKQVSDMASAIFSQALTVESSDVFRWSLNTRQ
                     SSIQMLDDTTTVTPLKRAIVTLRFNLR"
     gene            9804..10457
                     /locus_tag="VIB71_001302"
     CDS             9804..10457
                     /locus_tag="VIB71_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ8823036.1"
                     /translation="MPESETLSPDIHTKSHEDSPNTVKKQEEVMETQLEAKQGIHSIL
                     LFRLLKEASSEAATKLAFQTEHEVGKSRDVDGQKTKDGIIQSVGALEYDFKATSILAK
                     GDVLAAKLEKAMENGELVEIWDIDLEETSKNGDSDNKLANVWGIDKNGTNRGNGKYLA
                     TYYQGYISSFSAKKNAEENIEIEMEFAINGVGQKGFATLTDAQKAAVQYAFKDTTKG"
     gene            10517..10870
                     /locus_tag="VIB71_001303"
     CDS             10517..10870
                     /locus_tag="VIB71_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEQ8823037.1"
                     /translation="MQLEIKGKTHNVKFGTRFVAEMDKNHIAERQGFKFGAGLQSSVP
                     FLIDHSVVTLAEVIYTGTITEPPRPSLNDIYDYIDEVEDIEKLFDDVLDELRQSNASK
                     LFMAQVEKDLAEAKA"
     gene            10912..11241
                     /locus_tag="VIB71_001304"
     CDS             10912..11241
                     /locus_tag="VIB71_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823038.1"
                     /translation="MIVLNCIRYLGMTDINEIGRLTLYEYDLLMTGKALAAVDESHKA
                     HKQAWINHQVTATKLVGGKKNKKEVPVYKKFKDFFDYEEEIRKITQEIDEGYDKKGMD
                     LLLKANL"
     gene            11256..14891
                     /locus_tag="VIB71_001305"
     CDS             11256..14891
                     /locus_tag="VIB71_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEQ8823039.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLQSAIRSIDGLEKRSTGFSSVSQ
                     KASSMFKSMLGANLAGQAISAMTRTVSSGLGSMLGEMNSSAKAWKTFDANLADIGFGK
                     KQILAAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKSMGKNLDELVADIQAGRVK
                     TSDFLEAVKKAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKVDFSKFASNLGKFLEGINIDKIVSNISSAISSVTSKVKEFWGGFKQTGAI
                     SAFSGALKSVWGALKNVASAMSGGSWKNFGSIVGGIVKHVSNFAKAIADVVGKMEPGR
                     LQSWIATFAAVGGGLKLFEKLTGQSVVGSFLDKISTKFGLFGKKAKEGTDQAANGSRK
                     SGGIISQIFNGLGNIVKSAGTAISTAAKGIGTGIKTALSGAPPIISSLGTAISTVAQG
                     IGTGLAIAFRGLGAAIAMVPPTTWLALGTAILMVGAAFALAGTQADGISQILRTIGDV
                     VVQVLQQVTDSLATLLTIIANAIGSMLPIVAGAISQIVGAVAGGLSQLIIAVSTGVSL
                     VIGAFTGLLGGISGVINSISAVIQSLTGVITAVFNGIATVISSVGSTIKDVLTGLGTA
                     FEGFGNGVKSALEGVGAVIESFGSAVRNVLDGVANILDSMGTAALNAGRGVKEMAKGI
                     KMLVDLSLGDLVATLAAVASGLGKMASSAGEMTTLGSAMSKVANGMTRLATSATIAIT
                     GLTVFATTMATIKTAVATLPPVLTMAASGFTTFTTQAVAAVTGLAAINAPITMFKAQL
                     MTITPALAQAGAGFAAFVAQSSTFSTGLASAGPTIAAFNANLMSLSATTGVLVASIAG
                     LSAVLSVVSAGFSQIGASATATVGQIQAFASSTTVVSSAFASMQSMIQSAMAAIVSSI
                     ITSFNQAASQMQSILSRMLSQARTFGSQLEQQMRQSGQRSGQNLARGLSSQQGAVINA
                     ISSMVNAAVSRANAGAGPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARA
                     KAMIHSPSRLFAKRVGQYIPQGVAMGIDKNADVVDDSVGGLFDSINSFDFNIADRLTS
                     IGAKFQGVVKSESSQSLSQQQEFVHTAQPAYINFSLGGNEYEAFVSDITNQQAKIEKI
                     RLKRSSW"
     gene            14924..15703
                     /locus_tag="VIB71_001306"
     CDS             14924..15703
                     /locus_tag="VIB71_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEQ8823040.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGGKVLEDELNNGFGTFRTLTVS
                     GRDVVDLEHQTTSVLGRNGEYFHNATVEVRKLEIKAKITGKDNQSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKVVPEEVSNEQIIGLTFICYNPFKMSDVKTKKGTS
                     IQNGGLFQTKPIITLNLSSPTKEIKLLHVESQKYIRLTGTYTTDEIKIDMATGKITQN
                     GRNILGNLDMVNSRYFELLPGKNTLQCDNATITAEFREVYL"
     gene            15700..17751
                     /locus_tag="VIB71_001307"
     CDS             15700..17751
                     /locus_tag="VIB71_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ8823041.1"
                     /translation="MIYLFDKLERLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPNQKEDVFKLFKVIDYNLEDSKFYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGITNVRTLSYYYISPRAALIKIVEAFNCEFNVRY
                     TFINNKITSRYIDLKKRFGKPTGKQFEHGNNLLKIVYEESTDDIVTCLIGRGKGEEIQ
                     HEEAEPKDVEGHLPQEERRQGYGRRIEFTDVVWSVEKGDPIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKTELLKATWEELQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNRESRSRKEAVQNMI
                     DESLETITDLGMTFQEFLQGIEKRIETGKKEMEDNWRKVNLEFDNFKKKVEQEGLQFN
                     TLKEQIKEVDERTDKELEEFRATLKNLALPEEAIKKITETIKVDDIPSLKQNFDDLKN
                     KVSETSETARLNAEIIGTDGKTRYNKNLLVGDPNRTKTYDEDYIEVEANDGGFKRGET
                     YTISFSQTCELLKKVAVTLTQANNKGVKLVLTPTKAKMEAQTFEVAKDKQSIEVYPLS
                     YTAVLTGDWYKSKQIDLNASEVQELALEMAYKDVVDGNNATIAGQWSDSPQMILDGGK
                     K"
     gene            17748..18869
                     /locus_tag="VIB71_001308"
     CDS             17748..18869
                     /locus_tag="VIB71_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ8823042.1"
                     /translation="MTETIPLRVQFKRMKAAEWASSDVVLLEGEIGFETDTGFAKFGD
                     GQNTFSKLKYLTGPKGPKGDTGLQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQ
                     KEETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPS
                     SSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAV
                     NIVMRQPSAPNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPNVEAKYDENAA
                     ALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLNDDKFYVKPDGGFYAKETS
                     QIDGNLKLKDPIANDHAATKAYVDGEVEKLKALLAAKQM"
     gene            18882..20795
                     /locus_tag="VIB71_001309"
     CDS             18882..20795
                     /locus_tag="VIB71_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ8823043.1"
                     /translation="MSRDPTLTLDESNLVIGKDGRVHYTFTASQDNQTVRLASNCLGT
                     AHFNQLMIERGDKATGYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNSNL
                     WSKIKLTTNGMLREYHRDNITTEIIEKADGIATRISEDSDKKLALINDTIDGIRREYQ
                     DADRELSASYQAGIEGLKATMASDKLGLQAEIKMSARGLSQKYDDEIRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRIELESQISGLRAVQQSTASQISQEIRDRTGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTHTVRGLQSDVVSPTGKIQSRLTQLAGQIEQRVT
                     RDGVMSIISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNT
                     TVNGTFTTKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAIT
                     DLLEGKVIKARNGAMTIDLQSGQINHYTNESAMRRIDSSTASQFIKMTKSGFISEIGN
                     MQAAMTVIGSNSDGSENHENKTFGGIRIWNGKSSYQSTSFVELVGNRVAIYGNKNRSP
                     WLFDSTTSGYAYLIPQNDRGIKHVIGRADRKIDQIHVGDIYVQGERVAMMLKDLALKI
                     GYIGTGGWANRIG"
     gene            20809..20970
                     /locus_tag="VIB71_001310"
     CDS             20809..20970
                     /locus_tag="VIB71_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823044.1"
                     /translation="MQEKLLGKIINDLALKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            20973..21584
                     /locus_tag="VIB71_001311"
     CDS             20973..21584
                     /locus_tag="VIB71_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ8823045.1"
                     /translation="MRNWKVTGKYPQLDGTGAVASTHIIIAAEDGAVIPQLIKQDLTS
                     TNDTEIIKAALEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGNVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AVEGNLVFVHVNEPFTYEAQTLKDLESEDKVTVIKYADLVKQD"
     gene            21595..21891
                     /locus_tag="VIB71_001312"
     CDS             21595..21891
                     /locus_tag="VIB71_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823046.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANEFAMAQLKD
                     SIKELAYELKNLDREREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            21888..22073
                     /locus_tag="VIB71_001313"
     CDS             21888..22073
                     /locus_tag="VIB71_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823047.1"
                     /translation="MNNWFKKVAIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCILMNVSQIKEEE"
     gene            22159..23448
                     /locus_tag="VIB71_001314"
     CDS             22159..23448
                     /locus_tag="VIB71_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEQ8823048.1"
                     /translation="MHIDGSLGAQCWDGYADYCKYLGLPYANCTNTGYARDIWEQRHK
                     NGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSGYGWFLGQNQGGANGA
                     YNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVSAYQQADLTATCQQAG
                     TTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNLAQREADLFLSNLPTK
                     KVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSYKPFTLNNIDYQQIIA
                     KYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAGGLDKNIVLLADDSSK
                     VDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLRTDYYVESKPNASSADKEFIK
                     AGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            23722..>23939
                     /gene="spei"
                     /locus_tag="VIB71_001315"
     CDS             23722..>23939
                     /gene="spei"
                     /locus_tag="VIB71_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEQ8823049.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKANFFSGKRVDIFTL"
BASE COUNT         8089 a         4174 c         5343 g         6333 t
ORIGIN      
        1 caattgtaac cgcaatattc tttgctagtt tttcattgat accaacttcc ggttctaata
       61 aattagtagt gatgatggaa gatttaggga cagagataaa aataatggac cgcctattag
      121 ttgctacttt tttatctttc attagttctt tattatcttt tatttctcta ttctttagta
      181 agactgatac tgatttaatt tcaattttag tagtttcaag ttggttgagc tcaacagtaa
      241 tgatgttcct aagttcgttc tttgtgctaa gaacattaat tttgttagtt gaaacttata
      301 ataatttcaa aaataaatag gtcatcacat tgtggtggct ttttattatg gattggaggt
      361 ggtggaaaat cgcatacgag gaattaaccg aaaaacaaca gcgttttgtg gataagtaca
      421 tcaccacatt taacgctact gagtctgcaa aacaagctgg atattctgaa aaaagcgctt
      481 atagccaagg tcaacgcttg ttgaaaaatg ttgaaattca aaaagcaatg aaggaacgtt
      541 ttttggaggc aaaagatact aaaggagacc gtattcaaga tgttgcagaa acgttggaac
      601 aagatacatc gatagcccgt ggagaaatcc aaatatctga attcaaagaa acagatatgc
      661 tgacaggtca agtggttatc cacacgaaaa gagaatatac cccaagtcac gaagaacagg
      721 gtagggctag ggatagaatt tataaagtta atggagctta ctcagaaaaa cgtgaattag
      781 agcattctgg aacggtggtg tttgcaaatg aagacaacat ccctgattaa agtagatttg
      841 ccatcaacaa tcggtatagg ttatggcgct ttttggcggt ctagaaattt ttatcgagta
      901 gttaaaggca gccgtggatc taaaaaatct aaaacgactg ctttaaattt tatcgtcaga
      961 ctgctgaagt acccttgggc taacttattg gtcatccgta gatactcaaa cactaacaaa
     1021 caatctactt ataccgattt taaatgggcg tgtaatcaat taaaggttac acaccttttt
     1081 aagtttaatg agagtttgcc agaaataact gtaaaggcaa cgggccaaaa gatactgttc
     1141 cgtggacttg atgatgagtt aaaaatcaca tctattactg tcgatgttgg cgctttgtgc
     1201 tgggcttggt ttgaagaggc ttatcaaatt gagaccgaag ataagttttc aacagttgtc
     1261 gaatcaatcc gcggtagttt agatgctcct gattttttta aacagataac agtcacgttt
     1321 aacccgtggt cagaaagaca ttggcttaaa cgtgtctttt ttgatgaaga aactaaacgg
     1381 gctgatacat tttctgggac tacaacattt agagtaaacg aatggcttga tgatgtcgat
     1441 aaaagacgct acgaagattt gtacaagact aatccaaggc gggctagaat cgtgtgcgat
     1501 ggtgaatggg gcgttgctga aggtcttgtt tttgataact ttgaagtcgt agattttgat
     1561 gttgaaaaaa caattcaacg cgttaaagag acctcggccg gtatggactt tgggtttact
     1621 caagacccta caactcttat atgtgttgca gttgacctcg caaacaaaga gttatggctt
     1681 tacaacgaac attatcaaaa ggctatgtta acagatcata ttgtcaaaat gataagagat
     1741 aaaaacttgc ataggtctta catcgcaggg gatagcgccg aaaaacgcct cattgcagaa
     1801 ataaaaagta aaggggtgtc tggaattgtc ccgagtatta aaggtaaagg gtcaatcatg
     1861 caagggattc aattcatgca ggggtttaag atatatattc acccatcttg cgaacacaca
     1921 atagaagagt ttaatactta cacttttaag caagacaaag aaggtaattg gttaaacgaa
     1981 ccgatagata agaataacca cgttattgat gcgattagat atgcgcttga aaaataccat
     2041 atcagaagca acgagtcaaa tcagtttgaa gttcttaggg ctggttttgg ttactagaaa
     2101 ggaaaataat gtacacagaa tcatttagag atagtacggg aaagactaaa acattagagt
     2161 ttaggttcca ccgtgaagct cgcatgaggt atcaagcgga aagtctagaa agcttgttaa
     2221 ccgaaaaata taagctactc cgtgaaatga ttgaacacca cgataaagtc caaaaaccac
     2281 gcatacaaga gcttctagat tatgcagagg gaaataacca caccatcagc gaaataggcc
     2341 gtaggaaaga cgatgacatg gctgatgttc gtgctgtgca taactatggt aagtatattt
     2401 caacgctcaa acagggctat ttggtgggta atcctattcg tgtagagtat attgatggta
     2461 ccgagcagca gcaagaccta ttaaaggacc tatctgttaa aaacaatttc caccagctga
     2521 accgcagatt agtaaaagac ctatccaagg ttggtcgagc gtttgaattg atttatcgca
     2581 gcatggatga caagacagag gtcgttagac tagatccacg ggaagtattt gttatctatc
     2641 aaaataacct agagcaatca agcttagctg gtgtgcggta ctataacaaa aatcaattag
     2701 atggtactac aaaaattgtc gagctttaca ccgataataa aatcctgaag tttgaatatg
     2761 atggtgattt aacacctatc ggagagactt cctctcatgc gtttggttcg gtgccaatca
     2821 cggagtacct caacacagat gacggcatgg gtgactacga gacagagttg tctttaatcg
     2881 acttgtatga tgcagcgcag tctgacacag ctaactacat gcaggatttg tcagacgcga
     2941 ttctggcaat cattggtcgt gtatcattcc ctggctatgt cgacactgcc gaaaaagcca
     3001 ttgaatactt acgtaagatg cgtaaagcta gattgcttaa cctcgagcct cctgtcgacc
     3061 aagacgggcg tgagggatct gtagatgcca aatatctata taaacaatat gacgtacaag
     3121 gaaccgaagc ctataaaaat cgtattgtgt ccgacatcca taaatttacc aatacgccag
     3181 acatgacaga cagtaagttt gccggtcaac aatccggaga ggcgttgaag tggaaagtgt
     3241 ttggtcttga tcaggagcgt gtcgacatgc aagctttatt tgagcaatct cttaaacgta
     3301 ggtacaaact aatcgctcgt gtaagccaac tgcttaaaga gattgatgat tttgacatca
     3361 gcaagcttaa aatcacattt acgccaaacc tacctaagtc gctacaagaa aagattgaag
     3421 cctttaaagc attgggtgga gagttgtcgc aagagacagc tatggctatt acagacatcg
     3481 tggaagatgc taagaaagaa attagcctta tcaacagcga gtcgaaatca cgtagtcaac
     3541 tagcgcagaa gttagaagaa accagtagat tgactgatag ggagttagct catgaccacc
     3601 agaaagagta aatactggcg tgaccgtatc aagaaagaaa tggatgctaa agaggcagac
     3661 gatatctctc ttgagcaatc catgaagcaa ttgcacgatt atcatttcag gaatatcgaa
     3721 aaagaaattg agtcgtttta tcaacgttat gctgacaaag agaaaataga cctttcagaa
     3781 gcccgtaaga gagcttctga gcttgatatt tctgcttacc agaagaaagc taaggaactt
     3841 gttgcaaagg ctgagaagct acgaaaagag gggagaacgg taacaagaga tgattttacc
     3901 caccaagaaa atgcagacat gtctatttac aacttagcca tgaaaacgaa tgctttggaa
     3961 ctattgcgct taaacattga tttagaaatg caagaacttg ccaacggcga acacaagcta
     4021 accaagaaat ttcttgatga aggctatcgc aaagaaaccg agtttcaagc tgggctatta
     4081 ggattatcag ttgctagcca agcgagtgtg aaaagcttag ctgatgccgt tatcaatgct
     4141 aatttcaaag gagcaaaatg gtcagataac atttgggaca gacaagataa gttacgcagt
     4201 atcatatctc aaagtgttca gagtgctatc ctaagaggta aaaatggctt aactattgca
     4261 agggatatca gacgagaatt tgatgtgtca gcgtcttacg caaagcgact agcgataacg
     4321 gagcatgcaa gggttcagat ggaagttggt agattatcca tggcggagaa tggctttgct
     4381 atgtttgata tattgcctga gcctaaagca tgtgatgttt gcaaagatat agctaagcat
     4441 ggtccatatc accttgacaa gtggataata ggggaaaact ctccgccgtt tcatccgtat
     4501 tgtcgttgtg cagttgtagg attggataag aaacaagaag aaaaagtgaa tgataaatct
     4561 gaaaaatttg aaaacataac accgaatctc atgccgttat ttagtaagtt tgcaagtaaa
     4621 ataacagatt tgcaacgtaa aatagtgtac tctgctgatt tagcagatac cgggtacatt
     4681 agaacaccgc atgcgtttga tataaacaat accttgcgaa ataaaggcta caattatcta
     4741 aacgttgatg ataaactaat taccgacaca ttggatagtg tcatctcgat aaattcaact
     4801 cccaaaaata taaaagtata ccgctttgat gactttgagt tattaggttc aatcaacgaa
     4861 caaaacaata atatttttga ttcaggtaat tttatggata aattaaacca gggaggatta
     4921 tcatacacca acgatggata tacttctgca agttatgatg ttaaaaaaaa cgtgatggga
     4981 tatcgtccta ttaagactga aataaaagta cctaaaggaa gccatgttta tcttacagat
     5041 aatgaggaag aaagtgaaat tatactacca cgagggacaa agtatgatat aattaatgcg
     5101 aagataaatg aatatgaaga aatagaaatc actatggaaa taagaaagga gtaagcgatg
     5161 gatttttctg attttttgaa taaaaaacaa aaagagtggg atgaatctca tccaattcct
     5221 gactttagtg caatgagtga tgaagaattg ctttatcagc caatgagtga agctttagtg
     5281 tctgaaagat ttgctaaaga gttatctaaa gaggttagaa agcgtaattt attatcaaaa
     5341 taaaaacata ttattataga cggaagactg tggtcgcccg tctttttttg tacccaaaaa
     5401 caggaggaaa catgaatcgt gaaagtaaac caggtatgga aagcgtaaaa atcggatggt
     5461 tgacatactc tgttgaaaag gcatcggacc tgtaaggcaa agatggcaat tggggtctta
     5521 tacactacaa aacacaacaa attaaactag atgactcatt aaccgagcag ctcgaagatc
     5581 aaacacttat ccacgaaatt gttcatggaa ttttagttga ggcaggctat actaaccacg
     5641 aagaggatca agctaaccgc attggtctga ttttgtatca agtattgcag gataatgatt
     5701 ttagctggtt gtacaaaggg gaataaatat gaataaacgc atcaagaaaa aacgtaagtt
     5761 agaaacagca gttgtgatgc ttgttgcaga aaatgctatg caagcaaaag ctcttagaaa
     5821 tcaaaacaga cgaattgcag agctgagagc gattatacaa caaaacaccc aagcaataaa
     5881 tagagagttt gtaactgcta aaaatacgat tttagataac caattagcta ttaagtcaat
     5941 tggtgatgat gttaatcaca tcaagcaaaa ttataagcgg aagtggcgaa aataaatttt
     6001 aaactggtcg aattcgaccc ctttagaatc aaactaagtc gtaggaatac ggttttttta
     6061 ttatgtccaa gcattgacga cgataaaagc tatggaatta ataatcgggg acgatttaaa
     6121 acataggagg tgccaatcat ggcagaagaa acacaagtag ttgagacggt tgaagagcaa
     6181 gtggtacctg aagcaaaaca accgcaagac gaaaaaaagt atacagatgc agatgtggac
     6241 gctattatcg acaaaaagtt tgcgaagtgg aagtcagaac aagaagctga gaaatcggaa
     6301 gccaaaaaaa tggctaagat gaacgagaaa gaaaaagcag actatgaaaa gcagaagctg
     6361 ttagacgaat tgcaagagct aaaaaacgat aagacacgca atgagttaac agcagtagct
     6421 cgtcaaatgt ttgcagaatc tgaaatcaac gtcaacgatg acgtacttgg tttagttgtg
     6481 actttggacg cagaacaaac aaaagcaaat gtaacaacgc tagcaaacgc atttgctaaa
     6541 gttatcgctg atgaccgcaa ggctcttgta cgccagacca ctccgtcaac aggcggtggt
     6601 atcgcaaaac aaaccaatta cggtgctaac ttggctagta aggcagcaca acaaagcacc
     6661 aagctttttt aggaggaaat tatgaacaaa cgtaaagtaa caacatctaa agagattcta
     6721 cacaatctcg actatgaagc tatttcagta actttggatt caaacaaaat cggcaagaaa
     6781 gttgttccag ctggaacaat tttggcaggc aaagataaat ccatttttga agaccgcaaa
     6841 cagaaagtag aaaccgtgac aaatgaagaa gtctctacaa aagaatatgt cgatggtatt
     6901 ttatttacag atgtcgattt aacaaatggc gatgcagtcg gttcctgtgt ttatcgtggg
     6961 actatcaatg cagacaagct tgctgattca tctgttgcgg aaaattatga tgatttggaa
     7021 gaagtactac cacacattgt ctttatcaaa ggaggtaaat aaacatggca ttgatccacg
     7081 aaattatcac atcggaaaat atcaaaggtt tttataacgc taaaaacgaa aatgttgaaa
     7141 atacattggg agaaaaagca ttcccgccaa aacaacaact gggccttaag ttgtcattta
     7201 ttaaaggtgc agcaggaaaa ccggttactc ttaaagcggc cgcttttgac actaaggtgc
     7261 ctctacgtga ccgcatggct gttgaattgc ttgacgaaaa aatgccattt ttcaaggaag
     7321 ctatgtctgt taaagaggca gatcgtcaac aacttaacat tttgtctcaa actaaaaata
     7381 acgaacttat cgacaccatc ttggcatcta tctacaatga ccaggctacg cttattgcag
     7441 gtgctaaagc acgccttgaa gcaatgcgca tggaagtact atcaaaaggt aaaatccata
     7501 tccagtctaa cggcgtgatg aaagacatcg actatggatt ggccgaagat caaacgacca
     7561 aaccagacgc caaatgggat agcgcaggaa cagctacacc acttaaagac attgaaaagg
     7621 ctatcgaaaa aatggcagag cgtggttttg tgccagaagc tatcatcatg aactctaaga
     7681 catttagttt gattaaaaac gcagagagca ccttagatgt cgtgaagcct atggcaccaa
     7741 atggggcagc ggttactaaa cgtgacctaa acacatatct tgaagatgaa ctacaaatca
     7801 aagtcatcct aaaagatggc atgtttgttg gtgatgatgg tgaatctcgt aaatacttcc
     7861 cagatggttt tgcaacatta gtacctaacg gcaaccttgg ctacactgta tttggcacaa
     7921 ctccagaaca gtcagacttg cttggtggtg aagcgacaga tgcaaatgtc tcaattgtcg
     7981 aaactggtat cgcaatcaca acaaccaaga caactgatcc agtaaacgtc caaaccaagg
     8041 tatctatgat tgccttgcca tcatttgaac gcttggaaga agtacatatt attaatggct
     8101 tgcaagatgc ataaggaggt gctttatggc caaagttatt aagactttta gagataaagt
     8161 gacgactaat gcttattatg taggcgatga ttacaaagga gatcgtatcg aggaattgac
     8221 agccaatggt tacttggccg gaaatactcc taaactggat actgtcgaag aagttgacct
     8281 agataaactc aaaagcgatg aaatcaaggc aaaacttgac gaattgggca ttgagcacga
     8341 ttctaagctt aaaaaggcgg aattgttgga gcttttaaaa gctaacattt aacggaggtg
     8401 tttatggcaa atgtaaacac atttagcatt gtaaaaaatg tcaagctcga tttaggcatt
     8461 gaggacgaca atcaagacca gttgttggag atgttgctaa atcgtattac agaccacttc
     8521 aaagcaaatt atggcgtgtt agaaattgac aatgcttttt cttttgtctt ggaagattgt
     8581 ctgattgctc gttttaaccg tagaggttca gagcgtgcca aaacagagga agtggaaggt
     8641 cataaaacaa cctactacga ccatttgaat gagtttgaac cctacgatgc catgattatg
     8701 acaaagctta atttaatcaa agacaaatct cgtaaagggg gactgtactt tttatgagat
     8761 atgcagatag agttacattt gttaaaacga cggatgagca atacaatccc gatttaggtg
     8821 agtatacgca cacagaggtc ataagtatca caaaaccttg ttttgtgatg gacatgggca
     8881 tggaaaagtc cgtacagatt tttggagatt atcaaaagga tcgtaaagtt atctacctaa
     8941 agcagcctta tacaaaagca tttgattatt gcgagtatga gggcaggaga tacaaaacgc
     9001 aggcaaataa gcttggcgct attgtttttt atctggaagg agatgactct attggtggct
     9061 gatatatctt taaaagtagt tggaacagct ggtttaaaaa agaaacttga gcttattatc
     9121 aaaaaagatg ccgtcaagaa gattgtcaga gacaatggga cgcagcttca aaggaaaatg
     9181 attaataaag cggtatttac aaaaggctat tcaacaggtg caactagacg ttctattacc
     9241 atgcaaatcg gcgatggtgg attgagtgtc aaggttaaac caggaactca ttatgccggc
     9301 taccttgaaa gaggaactcg ccttatgagc aaacaaccgt ttgttttgcc agctctaaaa
     9361 gagcaaaaag taaaatttag aaaagatttg gaggcgcttg tcaaatgatt aaaactagag
     9421 atcagtctat ttttgatgaa atgtttaaac gcatccagtc tttaggcttt acagtttacg
     9481 attataaacc gatgactgaa gttccatatc catttgtgga aatggaatct actgatgcgg
     9541 agtatattcc aaataaagac gacattaaag gttctgttga acttatgttg tctgtttggg
     9601 ggatgcagaa aaaacgaaag caggtgtctg acatggcatc tgctattttt tcgcaagctt
     9661 tgacagtaga gagttctgac gttttccgct ggtcattaaa tactcgtcaa tcatctattc
     9721 aaatgttaga tgacacaaca actgtgacac ctcttaaacg agcgattgtc acacttagat
     9781 ttaatttgag ataggaggta gaaatgccag aatcagaaac attatcccct gacattcata
     9841 ccaaaagtca cgaagatagt ccaaatactg taaaaaaaca ggaggaagta atggaaacac
     9901 aattagaagc aaaacaaggg attcattcaa tcttgttatt tcgtttgttg aaagaagcat
     9961 ctagtgaggc agcaactaaa cttgcttttc aaacagagca tgaagtaggt aaaagccgtg
    10021 acgtagatgg acaaaaaact aaagatggta ttatccagtc cgtgggggct ttggagtacg
    10081 actttaaagc aacatctatt ttagctaaag gtgacgtact agcagctaaa ctagaaaaag
    10141 ccatggagaa tggtgagctt gtagaaattt gggatattga tttagaagaa acaagcaaaa
    10201 acggcgacag cgacaataag cttgcaaacg tttggggtat tgataaaaat ggaacaaaca
    10261 gaggaaacgg taaataccta gcgacttatt accaagggta catctcaagc ttcagtgcta
    10321 agaaaaatgc tgaggaaaat attgaaattg aaatggaatt tgccatcaac ggtgttggcc
    10381 aaaaaggatt cgctacatta acagatgccc aaaaagcagc tgtacagtac gcatttaaag
    10441 atacaacgaa aggttaatca acaaggccag ttaattactg gtcttttatt tttaagtttt
    10501 taaaggagaa agaataatgc aattggaaat taaaggtaaa actcataacg taaaatttgg
    10561 tacacgattt gttgccgaga tggacaaaaa tcatatagca gaacgtcagg gatttaaatt
    10621 tggagctggt ctacaatcta gcgttccgtt tttaatcgac cacagcgttg ttactcttgc
    10681 ggaagtaatt tatacaggta caatcaccga accaccacgt cctagtttga atgatattta
    10741 cgactatatt gacgaagttg aagatattga aaagcttttt gatgatgttt tagacgaact
    10801 acgtcaatca aacgcatcaa agttgtttat ggctcaggtg gaaaaagacc tggcggaagc
    10861 caaagcgtaa caaatataaa aaagagttat tcttctcaag aaagctttga gatgattgtg
    10921 cttaattgca ttagatacct tggcatgact gacatcaatg aaatcgggcg attaactttg
    10981 tatgaatatg atttattaat gacaggcaaa gcactagcgg ctgttgatga atcacataaa
    11041 gctcacaaac aagcttggat aaaccaccaa gttacggcaa caaaacttgt tggtggcaag
    11101 aaaaataaaa aagaagtccc tgtttataaa aaattcaagg acttttttga ttatgaggaa
    11161 gaaatccgaa aaatcactca agaaattgat gaaggttacg acaagaaagg tatggattta
    11221 cttctcaaag ctaaccttta aagaaaggag gttaaatggg agaatcttat tctgttgaag
    11281 cggttttgac agctgttgat aaaacctttg gcaaaacatt acaatcggca atccgttcaa
    11341 tcgatggctt ggaaaagcgt tcaaccggtt tttcatcggt gtctcaaaaa gctagttcca
    11401 tgtttaaatc catgttagga gcgaatttag ccggacaagc tatctcagca atgacaagga
    11461 cagtgtcatc aggccttggc tctatgcttg gcgagatgaa tagttcagcg aaagcgtgga
    11521 aaacttttga cgccaattta gcggacattg ggtttggaaa aaaacaaatt ttggcagcta
    11581 aaacggcgat gcaagactat gcaactaaaa caatctactc ggcatcagat atggctagca
    11641 cgtatgcaca gttagcggca gttggtgtga aagataccgg aaagctcgta aaagcttttg
    11701 gcggtttagc tgcatctgct gaaaacccga agcaggccat gaagtctatc agtcaacaaa
    11761 tgacgcaagc agtaggaaga ccaacagttg catggcaaga ctttaggata atgctggaac
    11821 aggcgcctgc agggatggct aaagtcgcta aatctatggg taaaaatctt gatgaactcg
    11881 tcgccgatat ccaggcgggt agggttaaaa ccagcgattt tttggaagcg gtaaaaaaag
    11941 caggcaatga taagagtttc caaaagatgg caactgagtt caaaactgtt gaccaagcca
    12001 tcgacggtat gcgagaaggc ttatccaaca aattgcaacc agcgtttgaa aaagtgaacc
    12061 aatttggaat tagagcgatc gaagcaatcg gtaaacaact cgataaagtt gatttttcta
    12121 agtttgctag taatcttggg aaattccttg aaggaattaa tatcgataaa attgtatcta
    12181 atatttcatc ggcgatttca tctgtcactt caaaggttaa agaattttgg ggcggtttca
    12241 aacaaactgg agcaattagt gctttttcag gagctttaaa aagtgtttgg ggagcgttaa
    12301 aaaatgtagc tagcgctatg agtggaggca gttggaaaaa ctttggctct attgtaggcg
    12361 gaattgtaaa gcatgtgtct aattttgcaa aagctattgc tgatgttgtc ggtaaaatgg
    12421 aacctggcag attgcaaagc tggatagcca cttttgcagc agtcggggga gggttaaagt
    12481 tatttgaaaa gctaacagga caaagcgttg ttggctcttt tttagataaa atcagtacaa
    12541 aatttggatt atttggcaaa aaagctaaag aaggaaccga tcaagcagcg aatggctctc
    12601 gtaaaagtgg tggaatcatc agccaaatct ttaatggctt gggtaatatc gttaagtctg
    12661 ctggtacagc catatcaaca gctgcaaaag gtatcggtac agggattaaa accgccttgt
    12721 ctggggcacc tcctatcatt agttctctag gaaccgcaat atcaacagtt gcgcaaggta
    12781 taggcactgg gctagcaatc gcttttagag gtttaggagc tgcaatcgct atggtgcctc
    12841 ccaccacttg gctagcttta ggaacggcta ttttaatggt aggagcggct tttgccttag
    12901 caggaactca ggctgatggc attagtcaaa ttttaaggac tattggcgat gttgttgtac
    12961 aagttttaca acaggtcact gatagtctag ccactttact aactattatc gcaaacgcta
    13021 ttggctctat gttgccaatt gtagctggag ctatctctca gattgtaggc gcagtagcgg
    13081 gcggattatc tcagctcatt atagccgttt caacaggggt atctctcgtt ataggagctt
    13141 tcacaggact tcttggtggt atttctgggg ttattaactc cattagcgct gttatccaat
    13201 cgctaactgg tgtgattacc gcagtattca atggcatagc tactgttatt tcatctgtcg
    13261 gttcgactat caaagatgta ttgacgggtc taggaaccgc ttttgaagga tttgggaatg
    13321 gtgtaaaatc agctctagaa ggtgttgggg cagtaattga atcatttggt agtgcagtta
    13381 ggaatgtcct tgacggtgtt gcaaatatcc ttgattctat ggggactgcg gcacttaatg
    13441 caggccgtgg cgtcaaagag atggctaaag gtattaagat gcttgttgat ttatcccttg
    13501 gagatttggt tgctacatta gcagctgtgg caagcggtct agggaagatg gctagctcag
    13561 ctggcgaaat gacaacatta ggttctgcta tgagcaaagt agccaatggt atgacacgtc
    13621 tagcaacaag tgctacgata gcaattactg gattaacagt ctttgccacc accatggcaa
    13681 ctattaagac agcagttgca actctaccgc cagtcctaac gatggcagcg agtgggttta
    13741 ccacatttac tactcaggcg gtggcagcag tgactggatt ggctgcaatt aatgctccaa
    13801 tcactatgtt taaagctcaa ctaatgacaa taacaccagc tctagcacaa gctggcgctg
    13861 gctttgccgc gtttgttgct caatcatcaa catttagtac aggtttagca tctgccggtc
    13921 ctacaatagc agcattcaat gctaatttga tgagcttatc tgcaacaaca ggagtgctag
    13981 ttgcatcaat agctggttta tcagctgtgc tttctgttgt atcagctggc tttagccaaa
    14041 taggggcttc tgcgacagca actgttggtc aaatacaagc ttttgcttct agtacaacag
    14101 ttgtttcgtc agcatttgct agcatgcaat ctatgattca atctgccatg gctgcaatag
    14161 taagcagcat tataacatca tttaatcaag cggcctctca aatgcaatca atcttatctc
    14221 gaatgctatc tcaggccagg acatttgggt ctcaactaga gcaacaaatg agacaatcgg
    14281 gacagcgttc aggacaaaat cttgctcggg ggctatcttc tcaacaaggt gctgttatta
    14341 atgctatttc tagcatggtt aatgctgcgg tatcaagagc caacgcggga gctggtccta
    14401 tgcgtcaagc tggagcgtac atcggacaag ggcttgcgca aggaatgtat tcagcgctag
    14461 gagctgtaac agctgcagca aacgcccttg tagcacaagc cgagagagca gcaagagcca
    14521 aggcgatgat tcattcgccg tcaaggttgt ttgcaaaacg agttggtcaa tatatcccgc
    14581 aaggggtagc tatgggtatc gacaaaaacg ctgatgtcgt tgacgactct gttggcgggt
    14641 tatttgatag catcaatagc tttgatttta atatcgcaga tagactgact agcattggag
    14701 ctaaattcca aggtgttgtc aaatcagaga gttcgcaatc gttatcgcag caacaagagt
    14761 ttgtacatac agctcaacca gcgtatataa actttagttt aggcggaaac gaatacgaag
    14821 catttgtaag tgacatcact aatcaacaag caaaaattga aaaaatcaga ctaaagagaa
    14881 gcagctggta gttgtttctc ttagtttttt tgaaaggagt aaaatgtacg aatttaacga
    14941 tactatcaga ggtactccga aagttacttt taatttaaag acaacaattg gtggaaaggt
    15001 attagaagac gaactcaata atggtttcgg tacctttagg acattgactg tttctggtcg
    15061 tgatgtggtg gacttagagc atcaaacaac aagtgtttta gggcgaaatg gtgagtattt
    15121 ccacaatgcc acagtcgaag tcagaaaact agaaataaaa gctaaaatca ctggaaaaga
    15181 taaccagtca atgcgtttgc aatatgaaaa attaaacaga ttaattgtta gtcacaatca
    15241 agttttttta tcattttcag acgaacctga cagaaattat ctaggtatct ttaaatctaa
    15301 agttgttcca gaagaagttt ctaacgagca gattatagga ctaacattca tctgctacaa
    15361 tccgtttaaa atgtctgatg taaaaactaa aaaaggaaca tctatccaaa atggtgggtt
    15421 atttcaaaca aagcctatca tcactctcaa cctatcatca ccaacaaaag aaattaagtt
    15481 gttgcatgtc gaaagccaga agtatatcag attgactgga acttatacca ctgacgaaat
    15541 caagattgat atggccacgg gtaagattac ccagaacgga cgcaatatcc ttggcaattt
    15601 agatatggtt aacagtcgct attttgagct actacctggt aaaaatactt tgcagtgtga
    15661 caatgccacc ataactgcag agtttaggga ggtttatcta tgatttatct ctttgataaa
    15721 ctggagcgat tggtcgccac tgttggtact gacgatttgc tctcgtggca ttttaaggtc
    15781 aaaaataacg actgggatca agctagtttt gaggtaccgg tggattatga tatagagcca
    15841 tttgtctact ttggtttttt taactacgac cctaatcaaa aagaagatgt ctttaagctc
    15901 tttaaagtca ttgattacaa cctagaagat agcaagtttt acaaaggctt agacaaagct
    15961 gagagtgatc ttgataccat tgccattatc aaagataagc gctttagaca atcgtccgca
    16021 gatgcttgta ttgatggtgc tttagagggt acgggttatc aagtcggcaa agttgaggga
    16081 ataacaaatg ttagaacact tagttattac tacatcagtc cacgagcggc tctgattaag
    16141 attgtggaag cttttaactg cgagttcaat gtcaggtata cctttattaa taacaaaatc
    16201 actagtcgtt atatcgacct caaaaagcgc tttggaaagc caacaggcaa gcaatttgaa
    16261 catggcaaca acctgctaaa aattgtctac gaggaatcaa cagatgacat tgtgacttgt
    16321 ctgattggca gaggtaaggg tgaggaaatc caacacgaag aagctgagcc taaagatgtc
    16381 gagggacact tgccacagga agaaaggcgg caaggctacg gtcgaagaat cgaatttact
    16441 gatgttgtct ggtcggtcga aaaaggcgac ccgatagaca aaccagctgg tcaaaacttt
    16501 gtagcactag atagcgcaag ggaagaatac ggcttgtctc aaaatggtga gctaaaacac
    16561 cgctggggtg tctttgtcaa tgaggaaatc gaggataaga cagaactctt aaaagcaact
    16621 tgggaagaat tgcagcgttt gtcaatccct atcagaattt acaaggcaga aatcttagac
    16681 attggtccag agacgtggaa aggcgactca gtagccatta tctatgatga ggtaaaaata
    16741 gcttttgaaa ctcgggttga tgagattgat attgacaagc ttaattttaa caggtcagtc
    16801 gtaacacttg gtgattacag cgttgtccaa aatcgtgagt cacggtctcg taaagaggct
    16861 gtccaaaaca tgatagatga atctttagag actatcacag acttagggat gacatttcag
    16921 gaatttttgc aaggcatcga aaaacgcatc gagactggca aaaaggagat ggaagacaat
    16981 tggcgcaaag ttaaccttga atttgataac tttaaaaaga aggttgagca agaaggcttg
    17041 caattcaaca ccttgaaaga acaaatcaaa gaagttgatg aacgcaccga taaagagctt
    17101 gaagaattta gagccaccct caaaaaccta gcgttaccag aggaagcgat taaaaaaatc
    17161 acagagacta tcaaagttga tgacatcccg tctcttaagc aaaactttga tgacttaaaa
    17221 aacaaggtca gcgagacaag cgagacggca cgtctaaatg ccgagattat cggtacagac
    17281 ggtaagaccc gctacaacaa aaatttgctg gttggcgacc ctaaccgcac caaaacctat
    17341 gatgaggatt acatagaagt agaagctaac gacggtggtt ttaagcgtgg cgagacctac
    17401 acgattagct ttagccagac ttgtgagcta ctcaaaaaag tggctgtcac gctgacacag
    17461 gctaacaaca agggagttaa gttagtgctg acacctacca aggctaagat ggaagcacag
    17521 acgtttgagg tcgctaagga taaacagtct atagaggttt atcctttgag ctacacggct
    17581 gttttaactg gcgactggta taaatctaag cagatagatt taaacgcgtc ggaggtgcag
    17641 gaattggccc ttgagatggc ttataaagat gtggttgacg gtaataatgc cacgatagca
    17701 gggcagtggt cagacagccc gcaaatgatt ttagatggag gtaaaaaatg acagaaacta
    17761 taccattaag agtccaattt aagcggatga aagccgccga gtgggcaagt agtgatgtcg
    17821 tcttactgga gggtgagatt ggctttgaga ctgacactgg ttttgctaag tttggcgatg
    17881 gtcaaaacac ttttagtaag cttaagtacc ttactggtcc caaaggtcct aaaggagaca
    17941 ctggtctcca aggtaaaact ggaggaactg gtcctcgggg ccctgctggc aagcctggaa
    18001 cgacagatta tgatcaactc caaaataaac cagatctagg tgcgtttgca caaaaagaag
    18061 aaactaatag taaaatcacc aaattagaat caagcaaagc agataaaagc gctgtttact
    18121 caaaagcaga gtcaaaaata gagctagaca aaaaattgag cttaacaggc ggcatagtga
    18181 caggacaact acagtttaaa cctaataaaa gtggtattaa accctcatct tccgtaggag
    18241 gagcgattaa cattgatatg tctaaatcgg aaggtgctgc tatggtgatg tatacaaata
    18301 aagatactac tgatggacca ttgatgattt tacgttctga caaagatacg tttgatcagt
    18361 cagctcaatt tgtggattac agcggtaaga ctaatgctgt aaatattgta atgcgccagc
    18421 caagcgcacc taatttttcc tcggcactta atataaccag tgccaacgaa ggcggtagtg
    18481 cgatgcaaat tagaggcgtc gaaaaagcgc taggaacgct caaaatcaca cacgaaaacc
    18541 caaacgttga ggcaaaatac gatgaaaacg ctgcagcgtt atctattgat atcgttaaaa
    18601 aacagaaagg cggaaaaggt actgctgccc aaggaatcta cattaactca acatcaggca
    18661 cgacagggaa gttgcttagg attagaaacc ttaatgatga taagttctac gtcaagcctg
    18721 acggtggttt ttatgccaag gaaacttcgc agattgatgg caacctgaaa ctcaaggatc
    18781 ccatagcgaa tgatcatgcg gcaaccaaag cttatgttga tggtgaagtc gaaaaattaa
    18841 aagcactctt agcggctaag caaatgtaaa aaggaggata aatgagtaga gatccaacgt
    18901 tgacattaga cgagtcaaat ctcgttattg gtaaggatgg acgtgtgcat tatacattta
    18961 ctgctagtca agacaaccaa acagttagac tagccagcaa ctgcttaggc acagcgcact
    19021 ttaatcagct catgattgag cgaggggata aagcgactgg ctatgtggcg cctgtggttg
    19081 ttgagggtag cggtgagtcg acaggtgtgt ttaaaagtct tgaggagatg cttagtggtc
    19141 tacagtctat taatttagag ctgacagata ctaaaaactc caatctttgg tcaaaaatca
    19201 agctgacgac aaacggcatg ttacgtgagt atcatcgtga taacatcaca acggaaatca
    19261 tcgaaaaagc tgatggtatt gccacacgga ttagcgagga ttctgacaaa aagctagcgc
    19321 tcatcaatga caccattgat ggtatcagac gtgagtatca agatgctgat agggagctat
    19381 ccgcaagcta tcaggcaggc atcgagggac taaaagccac aatggctagc gataaacttg
    19441 gcttgcaagc tgagattaag atgtcagccc gaggcttatc tcaaaagtat gatgacgaga
    19501 tacgtaagct atcggctaag atcacaacaa cctcaagcgg cacgaccgag gcctacgaaa
    19561 acaagctcga gggtttacgt gctgagttta ctcgtagtaa tcaaggcatg aggatagagc
    19621 tcgagtctca aatcagcgga ctaagagctg tacagcagtc aacagctagc caaatctcac
    19681 aagagattag agacaggaca ggagcagtca gtcgtgtgca acaagactta gacagttatc
    19741 agcgtcgttt gcaggatgcg gaagataatt acagtagctt aacccataca gttagaggtt
    19801 tgcagagtga tgtggtatcc ccgactggta aaatccaatc acgccttact caactagcag
    19861 gacaaattga gcagcgggtt actagagatg gtgtcatgag tattattagt ggcgctggag
    19921 acagcattaa attagctatc caaaaggctg gcggcattaa tgccaaaatg tctggtaatg
    19981 agattatctc agcaattaac ctcaactcct acggagtaac aatcgcaggt aaacacatcg
    20041 ctctcgatgg caatacgact gtcaacggta cctttaccac aaagatagca gaggctatca
    20101 agattagggc tgatcagatt attgcaggca cgattgacgc tgctaggatt agagtgatta
    20161 accttaacgc aagtagtatc gttggtttag acgctaactt tatcaaagct aaaattggct
    20221 atgctatcac tgatttgctt gagggtaaag ttattaaggc tcgtaatggt gcgatgacaa
    20281 tagacttgca aagcggtcaa atcaaccatt acacaaatga gtcagccatg agacgtatcg
    20341 atagcagtac agctagtcag tttataaaga tgacaaagtc aggctttata tctgagatag
    20401 gtaacatgca agctgcaatg acggttatag gctctaatag cgatgggtca gaaaaccatg
    20461 aaaataaaac cttcggaggc ataagaattt ggaacgggaa gtcatcttat caatcgacaa
    20521 gttttgttga attagttggt aaccgtgtag caatctatgg aaataaaaat cgtagtccat
    20581 ggctctttga ctcaacaacg tcaggatatg cttaccttat ccctcaaaat gacagaggta
    20641 taaagcatgt catagggaga gctgatcgta agatagacca aatccacgtt ggagatatct
    20701 atgtgcaagg cgaacgtgta gccatgatgt taaaagattt agcacttaaa attggctata
    20761 taggtacagg tggttgggct aaccgcatag gataaattag gagaaacaat gcaagaaaaa
    20821 ttattaggta aaattattaa cgatttagca cttaaagttg ctaatttaac gctagaaaat
    20881 gctcaattaa aagcacagca tgaaatcgaa ttggaagaac taaacgcaca attggatgaa
    20941 gcaacagcac cgaaggaaga aggtaaataa acatgagaaa ttggaaagta acaggaaaat
    21001 atccacaact tgatggcaca ggagcagtcg caagcacaca tattattatc gctgctgagg
    21061 atggagctgt tatcccgcaa cttattaagc aagacttaac ctcaactaat gacacagaga
    21121 ttatcaaagc cgctttggaa gaatttaaaa aatctgaata cgttgaaatt gcaatgggcg
    21181 aagccgtgca aaaagtagac gaccttgaaa aaatctcaca ggaaaccgct aagaccgcta
    21241 aaacagccca aacagccgca ggattagcta aggtgtccgc agagcgtaca cagcgaatga
    21301 ttaacttgca aaccatccac gtattgacaa gtggtgggaa cgttgaaccc gatatctaca
    21361 aaggtatgtt agagcttatt gagcctgcta aacaaggcga gtatcaggct tatgacgtgt
    21421 ttactgttgt agatgagtcg cacgaagatc aagcggtaga agggaacctt gtctttgtac
    21481 atgtcaacga gccgtttact tatgaggcgc aaactcttaa agatttggaa tcagaggata
    21541 aagtcacagt tattaaatat gcggatttgg ttaaacaaga ttagaggtgg ttagatgata
    21601 gattttgtac aaattggtgc tttttgtggc gctgctttgt ctatcttggg tgtttgggga
    21661 tttatcgtca atccctttaa aaaagccatg gaagctaatg agtttgccat ggctcaactc
    21721 aaggactcaa ttaaggagtt agcttatgag cttaaaaatc ttgatcgtga acgtgagatt
    21781 accaaaaaaa ttatcgacag acacgaggag cgtttaggtc gcgtagaaga cgaagttatt
    21841 atcaacaagg agcgtattat tacgctattt aaaaaaggag aagaaaaatg aataactggt
    21901 ttaaaaaagt agcaattaaa acaattaaaa caatggcaca aacggccgtt ggtctaatcg
    21961 ggtcaagcgt gttaatcacg gatattaatt ggccaacaat gttgtcagca gtgctgttgt
    22021 caggactaac atgtatcctg atgaatgtgt cacaaatcaa ggaagaggaa taggtcatgc
    22081 gagcaatcac acgattagca ttagttatag caatcgcaat actgtatgtg ccattatctg
    22141 tggttgcttt gattttttat ccatattgat ggatcgcttg gtgcgcaatg ttgggatggc
    22201 tacgcagact actgtaagta tctaggactg ccatacgcaa actgtacaaa tacaggatat
    22261 gcaagggata tatgggaaca acgtcacaaa aatggtattt taaactactt tgacgaagta
    22321 gagactatgc aagctggaga tgtcgcaatt tttatggtag ttgcaggtgt tacaccgtat
    22381 agccatgtgg ctatttttga tagtgatgca ggtagtggat acggatggtt tttaggtcaa
    22441 aaccagggtg gagcaaacgg agcatataat ttagtaaaaa taccatattc aacgacttat
    22501 cctactgcat ttagaccaaa agtttttaaa aatgcagtta ctgttatagg taatatagga
    22561 ctaaataaag gcgattattt tattgatgta tcagcttatc aacaagcaga cttaaccgct
    22621 acttgtcagc aagctggcac tactaaaacg attatcaaag tatccgagtc actcgcttgg
    22681 ctgtctgata ggcatcagca acaagctaat actagtgacc ctattggtta ttatcacttt
    22741 ggacgatttg gaggagatag caacttagcg caacgagaag cagatttatt tctgtccaat
    22801 ttaccaacca aaaaagtctc ttacttagtc attgattatg aagactctgc aagtgccgac
    22861 aaagaagcta acactaatgc agttattgcg tttatggata aaattgcaaa cgctggatat
    22921 aagcctgttt attacagcta taaaccattt acgcttaata atattgatta tcagcaaatt
    22981 atcgctaagt acccaaacag catttggata gctggttatc cagactacga agtacgaaca
    23041 gagccacttt gggagttctt cccttcaatg gatggtgtgc gctggtggca gttcacaagt
    23101 gtaggagtag caggtggttt agataaaaat attgtattat tagcagatga tagtagcaaa
    23161 gtggatatac ctaagattga caaaccacaa agccagctta cttttaatca aaagctagat
    23221 actaacacta aattagacaa ctcgaatgta ccttactacg aagcaaccct tagaacagac
    23281 tattatgtag agtctaagcc aaacgcaagt agcgctgata aagaatttat caaggcagga
    23341 actcgtgtaa gagtctatga aaaagtgaat ggatggtcac gtattaacgc ttctcagtct
    23401 gaccagtggg tcgaagataa gtatttatct aatgcaacac aagtataaaa taggaggtaa
    23461 agctccttta gataagacaa atgccctcgc ttttgcgggg gctgtttttg ttataaagat
    23521 tttaattgtt atttaagcat tttcgttgat ttttttcttt tttgtgctaa aatattttgt
    23581 gatttcttat tattaaagaa gaatagggta cacttataag tgagaaaaat tgtaaatgtt
    23641 aattttaaaa agtttttaac ttcatctttt ctattgtggg tatttatatc agctataatt
    23701 ccaacgtgtt acgcgtatga gatgagtagt gtgggagtta ttaatttaag gaatttatac
    23761 tctacatatg atccaacaga agtaaaagga aaaataaatg aaggtccgcc attttcaggt
    23821 agtttgttct acaaaaatat tccttatggc aatagttcga ttgaattaaa agtagaactt
    23881 aatagcgtag aaaaagctaa ttttttttct ggtaaaaggg tggatatatt tactttgga
//
LOCUS       DAUGUF010000031        22703 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUGUF010000031 DAUGUF010000000
VERSION     DAUGUF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22703
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.031"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(10..348)
                     /gene="cadX"
                     /locus_tag="VIB71_001316"
     CDS             complement(10..348)
                     /gene="cadX"
                     /locus_tag="VIB71_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEQ8823050.1"
                     /translation="MKKDSICQVDVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDSRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(360..986)
                     /locus_tag="VIB71_001317"
     CDS             complement(360..986)
                     /locus_tag="VIB71_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEQ8823051.1"
                     /translation="MRYFMIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIY
                     LGQFLGSVSLIFLSLLFAFVLNYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKD
                     GLRKDNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVTLLTFLVMIYLLVFS
                     AQKLAQVPSVGETLEKYSRWFIAVVYLGLGMYILIENNSFDMLWAVLG"
     gene            complement(1267..1416)
                     /gene="rpmG"
                     /locus_tag="VIB71_001318"
     CDS             complement(1267..1416)
                     /gene="rpmG"
                     /locus_tag="VIB71_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ8823052.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(1432..1614)
                     /gene="rpmF"
                     /locus_tag="VIB71_001319"
     CDS             complement(1432..1614)
                     /gene="rpmF"
                     /locus_tag="VIB71_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEQ8823053.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            1834..3114
                     /locus_tag="VIB71_001320"
     CDS             1834..3114
                     /locus_tag="VIB71_001320"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEQ8823054.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLLEKLGIKD
                     VTLHLNSLGSPESRSAYRQTLIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKAMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGLALPIETEMDVYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            3452..5200
                     /gene="aspS"
                     /locus_tag="VIB71_001321"
     CDS             3452..5200
                     /gene="aspS"
                     /locus_tag="VIB71_001321"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEQ8823055.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIATVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANAQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            5193..6134
                     /locus_tag="VIB71_001322"
     CDS             5193..6134
                     /locus_tag="VIB71_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8823056.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIIPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            6154..7032
                     /locus_tag="VIB71_001323"
     CDS             6154..7032
                     /locus_tag="VIB71_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8823057.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            7075..7947
                     /locus_tag="VIB71_001324"
     CDS             7075..7947
                     /locus_tag="VIB71_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8823058.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(7974..8282)
                     /locus_tag="VIB71_001325"
     CDS             complement(7974..8282)
                     /locus_tag="VIB71_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ8823059.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(8370..10061)
                     /locus_tag="VIB71_001326"
     CDS             complement(8370..10061)
                     /locus_tag="VIB71_001326"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEQ8823060.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            10352..10789
                     /gene="argR"
                     /locus_tag="VIB71_001327"
     CDS             10352..10789
                     /gene="argR"
                     /locus_tag="VIB71_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ8823061.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            11129..13684
                     /gene="mutS"
                     /locus_tag="VIB71_001328"
     CDS             11129..13684
                     /gene="mutS"
                     /locus_tag="VIB71_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEQ8823062.1"
                     /translation="MTKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGYTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQESGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPP
                     QVESSSAVRQGQLSLFGDDEKAHEIRQALEAIDVMNMTPFQAMTTLYELKKLL"
     gene            13813..15795
                     /gene="mutL"
                     /locus_tag="VIB71_001329"
     CDS             13813..15795
                     /gene="mutL"
                     /locus_tag="VIB71_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEQ8823063.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLVISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGDVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            15806..17026
                     /locus_tag="VIB71_001330"
     CDS             15806..17026
                     /locus_tag="VIB71_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8823064.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLASFQNYRQVFQDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            17028..17624
                     /gene="ruvA"
                     /locus_tag="VIB71_001331"
     CDS             17028..17624
                     /gene="ruvA"
                     /locus_tag="VIB71_001331"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEQ8823065.1"
                     /translation="MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            17634..18194
                     /locus_tag="VIB71_001332"
     CDS             17634..18194
                     /locus_tag="VIB71_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEQ8823066.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLDDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVATFTSEEIADALENPSIIRHKLKLAATVNNAIA
                     VQKIQKEFGSFSTYLWNFVGGKPINNLVNQENLVPSQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            18263..19534
                     /locus_tag="VIB71_001333"
     CDS             18263..19534
                     /locus_tag="VIB71_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEQ8823067.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKSM
                     VNEELVPLLSKQYSTLYSKVLRFFGVGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVAYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            19623..20759
                     /gene="recA"
                     /locus_tag="VIB71_001334"
     CDS             19623..20759
                     /gene="recA"
                     /locus_tag="VIB71_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEQ8823068.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLAEHPELFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            21050..21448
                     /gene="spx"
                     /locus_tag="VIB71_001335"
     CDS             21050..21448
                     /gene="spx"
                     /locus_tag="VIB71_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEQ8823069.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            21561..21830
                     /locus_tag="VIB71_001336"
     CDS             21561..21830
                     /locus_tag="VIB71_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEQ8823070.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            21827..22246
                     /gene="ruvX"
                     /locus_tag="VIB71_001337"
     CDS             21827..22246
                     /gene="ruvX"
                     /locus_tag="VIB71_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEQ8823071.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            22258..22563
                     /locus_tag="VIB71_001338"
     CDS             22258..22563
                     /locus_tag="VIB71_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEQ8823072.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
BASE COUNT         6859 a         3851 c         4928 g         7065 t
ORIGIN      
        1 aaatagttgt tatcctagtt gattaaaaaa atctctgatt tcctcatctt ttataaaata
       61 atatataatt ttcccctctc ttctagagtc caagatgttt tgattggcta gtttacgaag
      121 atggtgggag gcagatgcca tactgagatt taataaacag gctatatcgc agacacagag
      181 ttcttcgacg gcaaggagat aaaagatgat atttatctgt ttattatcgg taaattttga
      241 taaaatgcga agtgattttt ggactttttc cttttcaagg tagttcgttg cggttgtaac
      301 attttgttga tttataacat ccacttgaca gatactatct tttttcataa ttttttctcc
      361 tagcctaaca cagcccatag catgtcaaag ctgttgtttt caatcaggat atacatcccc
      421 aatcctaaat agacaacggc aataaaccat ctgctatatt tttccaaagt ttctccaaca
      481 gaagggactt gtgctaattt ttgtgcagaa aaaaccaaga gataaatcat gactagaaaa
      541 gtaagtaaag tcactatcaa attcgctaaa tttaaggtgg taaaatatgg gacaaagaca
      601 ccaatattgt cagcgccaca acttgcaaaa gtaatcatag cgactagaaa aatcaggttt
      661 ttattgtctt ttcgcaaacc atcttttgca atagcttctc catcagaatc tcctaaaagc
      721 aaaactttta ggcctaggaa aattggaatc aaaccgagta aacctaaaat ctctttacta
      781 ggaatataat ttaagacaaa tgcaaaaagc aaacttagga atattagact aacagagcct
      841 agaaattgtc ctaaatagat gttaatgatg tcttttctgc tttttctttt ggcaaaaaat
      901 aacattagga taataagtaa gtctacggct gtcccagaat acaggattat tgaagtaaca
      961 acattttgaa tcataaaata cctcattcaa atatattttt gaatgtattc taacattaaa
     1021 ctttgtagat gtcaacttaa aatccaccaa aatatagata ataagttagt gtaccaaata
     1081 ttaaaaagcc ctgccatcga aatgatagca gggcttaact tcaatatcca gatgatatat
     1141 ttatctaaaa aaggtagagt aaaaggtaga gtttttattg atttgtagtg cgatataatg
     1201 agtttcaaaa aatcaaaaat cgcttaaaat caatattttg acgtctattg acgtgtactg
     1261 aaacccttac ttaacctcag taaaaacaac gtgtttacga agttttggtg agtatttttt
     1321 caattgaaga cggtctggag tgttacgttt gttttttgaa gtaaggtaca agcgttcacc
     1381 agattcttta tgttcaagtg taatatttac gcgcatggta tctcccttct attatttagc
     1441 ttcgttagct ttagcgattt tacgtccttt gtagtatcct ttgagtgata cacggtgtga
     1501 acgtgagtaa tctccagtag tttcgtcgaa ttgtacagat ggagctgtca atttgtagtg
     1561 tgtacgacgt ttgtttttct tcgcttttga agtgtgacgt gcaggtactg ccattttctt
     1621 attcttcctt tcgatgtgta agttttgatt ttcatcaact tcactatgat aacatatctt
     1681 ttttgtaaag taaagttact tgacaaaact ttttattttt acaatttcat ggtgaaaata
     1741 ctatcaaact aaagcaaatg atatatgctt gtttaaaata taagaaaaaa tggtagaatg
     1801 tttaaagaga aaactaatcg aagaggtaaa cttatgaaac ttcaaaaacc aaaagggacc
     1861 caggatattc tgcctgggga tgctgcgaaa tggcagtatg tggaatctgt tgcgcgtgat
     1921 acgtttagcc aatataatta tggagaaatt cgtactccta tgtttgaaca ctacgaggta
     1981 atctcgcggt ctgtaggtga tacgactgat attgtgacga aggaaatgta tgatttctat
     2041 gataaaggag atcgtcacat taccttgcga ccagagggta cagctccagt ggtgcgttct
     2101 tatgttgaaa ataaattgtt tgcgccagag gtccaaaaac ccgtcaaact ttattatatc
     2161 ggttccatgt ttcgctacga acgtcctcaa gctggtcgtt tacgtgaatt tcaccagatt
     2221 ggggtagaat gtttcggtgc tgctaatcca gcaacagatg ttgaaaccat tgcgatggcc
     2281 tatcacctcc ttgaaaaatt gggtattaag gatgtcaccc ttcatttaaa tagtttgggg
     2341 agccctgaga gtcgttcagc ttatcgtcaa accttgattg actacttaac accaatgcgt
     2401 gatcaattat ctaaagatag tcaacgtcgc ttggatgaaa acccactgcg cgtgcttgat
     2461 tctaaagaaa aagaagataa actagccgtt gaaaaggcgc cttctatttt ggattactta
     2521 gatgaggaaa gtcaggcgca ctttgaggca gtcaaagcta tgcttgaagc acttgacatt
     2581 ccttatgtga ttgacaccaa tatggtgcgt ggccttgatt actataacca cactattttt
     2641 gaattcatca cgtctgtgga gggttctgac ttaactatct gtgcgggtgg acgttatgat
     2701 agtttggtag gttattttgg tggaccagaa acccctggct ttggctttgg tcttggttta
     2761 gaacgtctct tgatgattat tgaaaagcag ggtcttgcct taccaattga gacagagatg
     2821 gatgtttacc ttgctgtgct aggtgatggt gctaatagca aagctttaga attggttcaa
     2881 gccattcgcc gtcaagggtt tacagctgaa cgagattacc ttggccgtaa gattaaggct
     2941 cagtttaaat cagccgatac ctttaaagca aaattggtaa tgactttagg agaaagtgaa
     3001 gttgaagcag gcaaagctgt gattaagaat aatcgtagtc gtcaagaagt ggaagtcagt
     3061 tttgaagata tgatgacaaa ctttgcgaac atctcagagc aattattatc ttaatgattt
     3121 tattgtcgtc ataagcttgt gttgatatga ttgtttagaa gataatcact aaaacaggtg
     3181 taacttctct ttttagaagg gagttgcacc tgtttgtttt ctgtaagggg attgattagc
     3241 tttcttagta ttctgtgagg acacctgata tgtcaaaatg ctgacgactc agtattcttg
     3301 ctttatcttt agaaaaactc tttttaaatg ggtggggttt ttaagggctt tttgctataa
     3361 tagtagggaa tgaattaatt gatttatata gtgaaaggaa ttggaaacga gcaggtttca
     3421 caggattctg tttgttttag ggaatttatt tatgaaacgt agcatgtatg cagggcgtgt
     3481 tcgcgaagaa cacattggaa cgacaatcac attgaaagga tgggtcagtc gtcgtcgtga
     3541 cttgggtggt ctcatcttta ttgatttacg tgaccgtgag ggtgtgatgc aattagtcat
     3601 taaccctgag gaagtttcca gtgatgtgat ggcaactgct gaacgcctac gtagtgaata
     3661 tgtgattgaa gtggaaggtt ttgttgaagc tcgacaacaa gccaatgata agttggcgac
     3721 aggaatggtt gagttaaaag tatctgcttt gaccatttta aacacagcta aaacgacgcc
     3781 ttttgaaatt aaagatgacg ttgaagtaag tgatgacacg cgtttacgtt accgttactt
     3841 agatttacga cgtccagaaa tgttagaaaa cttcaagcta cgtgcaaaag tgactcattc
     3901 tatccgtaat taccttgatg accttgagtt tattgatgtc gagacaccta tgttgacaaa
     3961 atcaactcca gaaggtgcgc gtgactatct ggtaccaagt cgtgttagcc aagggcattt
     4021 ctatgctttg ccacaaagtc cgcaaattac caaacagtta ttgatgaatg ctggctttga
     4081 tcgctattat caaattgtga aatgtttccg cgatgaagat ctacgtggtg accgtcaacc
     4141 tgagtttaca caagttgact tggaaacgtc attcctttct gaacaagaga ttcaagacat
     4201 cgttgaaggc atgattgcta cagtgatgaa agagacaaaa gaaatagatg taaccctacc
     4261 attcccacgt atgagctacg atgtagcaat gaatagctac ggctctgata aaccagacac
     4321 acgttttgag atgcttttac aagacttgac agtaactgtc aagggaattg acttcaaggt
     4381 tttctcagaa gcaccagctg tcaaggcgat tgtggtgaag ggaaatgcag atcgatactc
     4441 tcgtaaagat attgacaaat taactgagtt tgccaaacaa tttggtgcta aaggccttgc
     4501 ctgggttaag gtgacagatg gtcaattggc aggcccagta gccaagttct tgacagctat
     4561 tgagacagag ttgtcaagcc aattaaaact tgctgagaat gatttagttt tatttgtagc
     4621 ggatactctt gaggttgcta ataatacatt aggtgccctt cgtaatcgta ttgccaagga
     4681 ccttgacatg attgatcagt cgcagtttaa tttcctttgg gtggttgatt ggccaatgtt
     4741 tgagtggtca gaagaagaag gacgttatat gtcagctcat cacccattca ctcttccaac
     4801 gccagaatct gctcatgagt tagagggtga tttggctaag gtacgggcta ttgcttacga
     4861 catcgtttta aatggttacg agcttggtgg tggtagcctg cgtatcaatc aaaaagagat
     4921 gcaagagcgc atgttcaagg ctcttggctt taccgctgat gaagctaacg cccaatttgg
     4981 tttcttacta gaagcgatgg actacggctt tcctcctcat ggtggcttgg caattggtct
     5041 tgaccgtttt gtcatgttgc ttgctggaaa agacaatatt cgagaagtta ttgccttccc
     5101 taaaaataac aaagcctctg atccaatgac gcaagcacct agtcttgttt ctgaaaacca
     5161 attagaagaa ctcagtcttc aaatagaaag tcatgattaa gaaaacaacc tataagaaaa
     5221 aagttaaata tgtcattagt agaggggcca agaaagttgg cctactccac gctctaagaa
     5281 gtatttcaag agaaaaatat gcagagaaga tttcggcttc tctgctttat ggcattctct
     5341 ctagtattgc tgtgaatttt ttcttccagc ctgggcatgt ttattcaagt ggagcaactg
     5401 gtctagcaca ggttttttca gctcttagtc atcgtctttt aggctatgat tttcccatcg
     5461 cctttgcgtt ttatttgatt aatattcctt tgcttatttt agcttggtat aaaattgggc
     5521 atcaatttac catttttacc tttatcacag tcagcatgag ttctttcttt attcaaatca
     5581 tacctcaagt gacgctgacg actgatcctc ttatcaatgc tatttttggt ggtttggtta
     5641 tgggaatggg aattggtaca ggtctcaaat cacgtatctc tagtgggggg actgatattg
     5701 tcagtttgac ccttagaaaa cgaacaggca aggatgtggg cagtctctca ttgatggtta
     5761 atggtgcaat tttagccttt gcagggattt tatttggctg gcagtacgcc ctttattcta
     5821 tggtctctat ctttgtatca agtcgtgtta cggatgccat tttcaccaag caaaagaaaa
     5881 tgcaggcaac tattgttacc agccatccag agcgtgtgat tcatatgatc cataaacgtc
     5941 tgcatcgcgg ggtgaccagt atcaacgacg cagaagggac ttacaagcat gaacaaaaag
     6001 cagttttgat taccattttg acatgtgaag aatacccaga attcaaatgg ctgatgttaa
     6061 aaacagaccc acaagccttt gtttcagtgg ctgagaatgt tagaattatc ggtcgttttg
     6121 tggaagatga ttaagaaaaa cacaggaggt gtcatgtcaa ttgaccaacg tttacagtta
     6181 aagaaatttt gctttattat tttaggagct gctatctacg cctttgcttt tgtttatttt
     6241 tacatggcta atcgcattgc agccaatggt ttagctggtc tcaccctagt tggtaaggca
     6301 ctttttgaga ttgatccttc tttgataggc tatttgatta atttgccttt ggtcttgctg
     6361 ggagctagat gttttgggaa aagagccatg gtttacacag taacgggtat tttatcactt
     6421 tacttttttg tgtggctgtt tcaacgcttt cctttggtcg ttgacttgga ccatgacaat
     6481 ttagtcgttt ccttgatggc tggaattatt ggtggtctag gtggcggtct tgtgtttcgc
     6541 aatggtggaa ccattggtgg agcagatatt attgctaagt tattagaaga caagttagga
     6601 ctacagctga atcaagctct tttaggcatt gatctttttg tcatgattgt ctctttgact
     6661 tatatttccc tgccgcaaat gatgtatgct ctgattgcta gctttatgta tggtcaaatt
     6721 gttcgcttgg tacaacaagg tggttattca gcccgtggca tttttatcgt ttcagaacaa
     6781 gcggagaaaa ttgcccggtt catcatggac gaattgggaa gaggagttac ttatctaaca
     6841 ggtgaaggag cctactctgg tcgccgtaaa aaagtgattt atgtggcttt ggggcgaaga
     6901 gatattaggg aattaaaagc ttttttaact caggttgatc ccaatgcctt tatcacttat
     6961 tttgatgtta atgaagtcaa tagcccagaa tttttaacta ttaaaagcaa ataccataaa
     7021 aagagaaaat aaatgagcat tagagttgcc tgcgaagaat agtgaggata aaggatggca
     7081 catcacgata aattgactaa actactaaaa ctgtttttga ttgccctagg tgtagccatt
     7141 tataccttcg gttttgttaa ttttaacatg gctaatgctt tggctgaagg tggtgtggca
     7201 ggaataacct tgattttaca cgcgcatttt gggattaatc ctgcttactc ttctctctta
     7261 tttaatcttc cactttttat tttaggggca aagatttttg ggaagcgttc tttggctcta
     7321 accatctatg gaacagttct gatgtccgct tttatctgga tgtggcaaaa agttcctatc
     7381 gaacttggct tggaaaatga catgatgttg gtggctgtag tggcaggtct cttttcaggg
     7441 attgggagtg gcattgtttt tcgctatggt gcaaccacag gtggaacgga tattattggt
     7501 cgcattgcag aagaaaaatt tggagctaag ctaggtcaaa ctttgctttt ggtggatgct
     7561 cttgtattga cagcttcgtt gacttatgtg gatttaaaac acatgcttta tactttggtg
     7621 gcaagctttg tttttagcca aatgattagt gtggttcaaa atggtggtta cactatccgt
     7681 ggaatgatta ttattaccaa gcattcagag gctgccgctc aagctatcct aaccgaaatc
     7741 aatcgtggag tgacttactt gaaaggtcaa ggagcttact ctggtaatga ttacaatatc
     7801 atgtatgtga ccttgaaccc aactgaagtt cgggaagtca aacgtatttt agctggtttg
     7861 gatccagatg cctttatctc cattattgat gtggacgaag ttattagctc tgattttaaa
     7921 attcgccgaa gaaattatga taaataaaaa tacaggtcaa acagcctgta tttttatttt
     7981 ggtcccccac ttaagaaact accaagcata atagctgata tagcagttcc cttgtaatgg
     8041 ctagcttttg tttttaccaa gcgactaaga tcaaatatgc ttttaggagc atcaaattga
     8101 tgtgttaaga tgtattgatt gataagtgag tcaatttttg tagctaggag tgagctcatc
     8161 ccctcttttt caagttgact ggcgagctcg aagatcgctt gacgaaaata atcatcggct
     8221 tgtattactt gttcgctata aactttacta agagcatcta atatttcttt ttctgatggc
     8281 atggcattct cctgtaacat attgtgctat tattataata taaaaaacta agactgtcat
     8341 aaatgtgaca gccttagtaa tgttattact tacatttcat ttggtgcgtc aacaccgagt
     8401 aagcgaagcg cttctttaag aacagtagca gttgcatagc agagagctaa gcggttatca
     8461 cgttctgagt tgtcgtcaag aatgcgagtg tgagcataat atttgttaaa gctttgggct
     8521 aagttaatag caaatttagc cataatagaa ggctcaaagt tatctgatgt tcgcttgata
     8581 atgcgtggga aatcttggat aagtttgata atttcccagc tttcagcatc agctaaactg
     8641 taagtggtgg ttgcagatgg cgtaaagtca gctttacgta gaatagattg gatacgagca
     8701 tgagcatatt gaacgtaagg tccagtttct ccttcaaagg aaaccatggc ttcaaggtca
     8761 aagtcatacc cattcatacg atctgttttg agatcgtaaa acttgatggc accgacacca
     8821 acagcgtgtg caacggcttc tttgtcagca aggtttggat ttttcgcttc aatttgagaa
     8881 gctgcacggt taatggcttc agcaaccgta ggttcaagaa gaataacatt acctttacgt
     8941 gttgataatt tagcaccgcc ttttgtgaca agtccaaaag caacgtgtgt catatcatct
     9001 gaccaatcgt aacccatttc ttttagcact gcttttaatt gtttgaagtg agcagcttgc
     9061 tcattaccaa caacataaac ggatttagca aagtcataag tgcgcttacg gtaaagtgcg
     9121 gcagctaggt cacgggtaat gtaaagagta gcgccatctg attttttgat caaggcaggg
     9181 tgttcaatgc cgtatttttc aaggttaaca acttgggcac ctttagattc tacaagaagg
     9241 tttttagctt ctaataagtc aagaacctca tccattttgt cattatagaa ggcctcaccg
     9301 ttgtaactat cgaaggtgac atgtaattgg tcataaagtc ggttgaactc aagtaaactt
     9361 tcatcacgga accattgcca taattcagta gcttctttgt cgccatcttc caatttacgg
     9421 aaccattcac gagcttcttc atcaacggtg ggatcagttt cagcttcagc attgatacga
     9481 acgtaaagtt ttaagagttc atcaatagga tgtgcctgaa cagcagcttc atctccccat
     9541 tttttgtagg caacaatgag cataccaaat tgtttacccc agtcaccaag gtgattgatt
     9601 tttacaggtt tatagcccat tttggcaaaa atgtgagcga gactatcacc aataactgtt
     9661 gagcggaggt gaccgattga aaatggctta gcgatgtttg ggcttgacat gtcaatagca
     9721 acatttcgcc cttgaccttc gtcttgctga gcatagtctg aacctgctgt aatcacttgt
     9781 tcaaggacct gtgaggaaat cttagcttta tcaaggaaaa agttgatgta agggccgaca
     9841 gctacgactt tttcaaattg gctctcatca atctgttcag ctaactcgct agcaatcatt
     9901 tgaggggctt tgcgaaggac ttttgctaaa ctaaaggctg gaaaggcaag gtctcccatg
     9961 tcagaatttt ttggggtttc aagcaagtta aaaatagcat cttgttctaa ttctggaaca
    10021 actttagcta tttcacttgc gattagagtt ttagtatcca tacagcgtct cctaaaaatt
    10081 gtttgtcacc ctattctaac atatttcttt aaaataaacg aggagaggat tgataaatta
    10141 tactgaaact ttcaaggaaa tgaattgctt gaggttgttg tttttctgaa aatgttataa
    10201 aaagagaaat gaggtttctt ttcaacagtt ttcaagtgaa attctagttg aatttgataa
    10261 aaaattgctg aaaatagctg ggcgaagatg aaataataca ctttttttgt tataatttga
    10321 gaggataatt atacaattgg ggtgatatat catgaataaa atggagcgtc aacagcagat
    10381 taagcgaatc attcaagcag agcatattgg cacacaagaa gatattaaaa atcaccttca
    10441 aaaagaaggc attgtggtca cccaagcaac tctatctcgg gacttaagag aaattggcct
    10501 tttgaaattg agagatgaac aaggcaaact ctattatagt ttgtctgaac ccgttgcaac
    10561 accatttagt cctgaggtgc gtttttatgt tttgaaagtt gatcgagcag gttttatgct
    10621 ggttctccat accaatttag gagaggctga tgttctagct aatttgattg acaatgatgc
    10681 cattgaagat attctaggaa ccattgctgg tgcggatacc ttgcttgtga tttgcagaga
    10741 cgaagagatt gctaaacgct ttgaaaaaga tttggctgca ggcctatgac tagctatcaa
    10801 gagtctttga cacaattgat tcttgctatc catgaattct agtatcgttg cttataaaga
    10861 agtgaagcaa tagctgtcta agctccatga ttttaaaaag taagcttatc agatgaaacg
    10921 ctatcaacaa gatgccttgc ttttcaaaaa aaaatagata aagaaaaggc tgcgacagta
    10981 tctgcaagca gggcaaaaga actagaagat aggctcagtc atcagccatt attaattgat
    11041 gattatcgag aaaagatgca agatgcaagt gatgtgattc agtatatcac caaacgtata
    11101 gaagatcagt taaacaagga gttaacaaat gacaaaaact aacatttctc ctggaatgca
    11161 acagtatctg gacatcaaaa aagattatcc agatgctttt ttgcttttta ggatgggtga
    11221 cttttatgaa ttattttacg aggacgctgt caaagcagca caactcttag aaattggttt
    11281 gaccagtcgc aacaagaatg cggaaaatcc aattcccatg gcaggcgtgc cacatcattc
    11341 tgcccaacaa tacattgatg tgttaattga gttgggttac aaggttgctg tcgcagaaca
    11401 aatggaagac ccaaagcaag ctgttggggt ggtgaagcgt gaggtcgttc aagtcataac
    11461 tcctggaacg gttgtggatt cagctaagcc agatagcgcc aataactttt tggtagctgt
    11521 tgactttgat ggttgccgtt atggattggc ttatatggat gtatccacag gtgaattttg
    11581 cgtgacagat ttggcggact ttacgagtgt tcgtagcgaa atccaaaacc tcaaggcaaa
    11641 agaagtctta ctaggttttg atttatctga agaagaacag acgattttgg tcaagcagat
    11701 gaatttgctg ctttcttatg aagaaacggt ctatgaagat aaatctttaa ttgacggcca
    11761 attgacaacg gtagaactga cagcggcagg aaaactcttg caatacgttc acaaaacaca
    11821 aatgcgagaa ctcagccact tgcaagcctt ggttcactat gagatcaagg attatttgca
    11881 gatgtcgtat gccactaagt caagtttaga tttggtagaa aatgctagga ctaataaaaa
    11941 acatggaagt ctctattggc tgttagatga aaccaagaca gctatgggga tgaggctttt
    12001 gcgctcatgg attgatcgac ctttggtttc taaagaagct attttagagc gtcaagaaat
    12061 tattcaagtt tttctgaatg cttttattga gcgaaccgat ttaagcaata gtttaaaagg
    12121 tgtttacgac atcgaacgct tatctagtcg cgtgtctttt ggcaaggcaa atccgaaaga
    12181 tttacttcaa ttggggtata ccttagccca agtgccttat atcaaagcta tcttagagtc
    12241 ttttgacagt ccttgtgttg acaaacttgt caatgatatt gacagtttgc ctgagttgga
    12301 atacttgatt agaacagcca ttgatccaga tgcaccagca actattagtg aaggcagtat
    12361 tattcgtact ggttttgatg agcgcttgga ccattatcgt aaagtgatgc gagaaggaac
    12421 aggttggatt gcggatattg aggccaaaga gcgtcaagaa agtggcatta ataacctaaa
    12481 aattgattac aataaaaaag atggttatta ttttcacgtt acgaattcaa atcttagctt
    12541 agttcccgag cattttttca gaaaggcaac tttaaaaaat tctgagcgtt atggaacagc
    12601 agaattggct aagattgaag gtcagatgtt agaggctagg gaagagtcat ctagtttaga
    12661 atacgatatt tttatgtgta ttcgagctca agttgaaacc tatattaatc gtttacagaa
    12721 actggctaaa actttggcaa cggtggatgt tttgcaaagt ttagcagtcg ttgctgaaac
    12781 caatcattat attcggccgc agttcaatga taatcatgtg attacaattc aagaaggtcg
    12841 tcacgccgtt gttgaaaagg ttatgggagt gcaggaatac attcccaata gtatctcttt
    12901 tgaccaacag accagtattc agctgattac aggtccaaat atgagtggta agtcgactta
    12961 tatgagacag ctggccttaa cggttatcat ggcccagatg ggttcatttg tggctgctga
    13021 tcatgttgat ttacctttat ttgatgcgat ttttacgcgt attggggctg ctgatgattt
    13081 gatttctggg caatcaacct ttatggtgga gatgatggaa gcaaaccaag caatcaaacg
    13141 cgcaagtgac aactctctta ttctatttga tgaactggga cgaggtacgg caacttatga
    13201 tggtatggct ttagcccagg caattattga atatatccat gatagagttg gtgctaagac
    13261 catatttgca acgcattatc atgaattgac agatttgtca actaagttga caagtctagt
    13321 caatgttcat gtagcaacgc ttgaaaaaga tggcgatgtt accttccttc ataagattgc
    13381 tgagggaccg gcggataaat cttacggtat tcatgttgca aaaatagcag gactgccaaa
    13441 atccctatta aagagagcag acgaagttct gacccgttta gaaacacagt cacgatctac
    13501 tgagataatg tcagtccctc cacaagttga gtcaagcagc gctgttagac aggggcaatt
    13561 atcccttttt ggtgatgatg agaaagctca tgagattagg caagcactgg aagctattga
    13621 tgtcatgaac atgaccccgt ttcaagcaat gacaactctt tacgaattga aaaagttgtt
    13681 atagtctttc agctgaaaat gaaaaagatg ctttctatat tgaaggcatc tttttgttct
    13741 gtcaaaaacg gtccgaggcc ttcggctatt tattaagtgt gttataatag tccataagaa
    13801 tgcgaggaaa ttatgacaaa cattattgaa ttaccggaag ttctcgccaa ccaaattgca
    13861 gctggtgaag ttgtagaaag gccagcgagt gttgtcaagg aattggttga gaatgctatt
    13921 gatgctaaaa gtagccagat taccgttgaa attgaagagt ctggccttaa gatgatacag
    13981 gttacagaca acggtgaggg aatgtctcat gaagatttac ctttaagtct gcgtcgccac
    14041 gctactagta aaattaagag tcagagtgat ttgtttagaa ttagaacact tggcttccgt
    14101 ggagaggctt taccgtctgt tgcctctatc agtaaaatca cgataaaaac agcaacaaaa
    14161 gaagtcactc acggttctct tcttatagct actggtgggg aaattgagac acttgaagcg
    14221 atctcaactc ctactggaac caaaattaag gttgaaaacc ttttttacaa cacgcctgct
    14281 cgtctcaaat atatgaaaag tttacaggca gaattagctc acattgtaga tgtggtcaac
    14341 cggttgagtt tggcacatcc agaagttgct ttcacactga ttagtgatgg tcgccaatta
    14401 actcagacat caggaactgg cgatttacgc caagcaattg cagggattta tggtttaaat
    14461 actaccaaaa aaatgctggt tatctctaat gctgatttgg attttgaagt ttccggctat
    14521 gttagcttgc cagagttgac acgcgccaac cgtaattaca tgacgatttt ggttaatggg
    14581 cgttacatca agaatttctt gcttaatcga gcaattcttg atggttacgg ttctaagctc
    14641 atggttggac gtttcccaat tgttgtgatt gatattcaga ttgatcccta tttggccgat
    14701 gtcaatgttc atcccacaaa acaagaggtt cgtatttcaa aagagcgtga attaatggct
    14761 ttaattagca cggctatttc agagagtctt aaggaacaag atttgattcc agatgctctg
    14821 gaaaacttag ccaaatcaag cacacgacat ttctctaaac cagagcaaac acaacttcct
    14881 ttacagtcta gggggcttta ttatgatcct caaaagaatg acttttttgt caaagagtcg
    14941 gctgtctcgg aaaaaatacc tgaaactgat ttttattccg gcgctgttga caacagtgta
    15001 aaggttgaaa aagcagagct gttaccccac tcagaagaag ttataggacc ttcttcggtt
    15061 aaacacgcaa gtcgtcccca gaataccttt accgagactg atcatcctaa tcttgactta
    15121 aaaaacagac aaaagttatc tcaaatgttg aatcgcttgg aaaatgaaga gcaatcagtg
    15181 tttcccgaat tggattattt tggtcagatg cacggaactt atctctttgc tcagggaaaa
    15241 gatggtttat ttataattga ccaacacgct gcccaggagc gggttaaata cgaatattat
    15301 cgtgataaga ttggcgacgt tgacagtagt ttacagcaat tgttggtgcc ctatttgttt
    15361 gagttttctg gttctgattt cattaactta caggagaaaa tggcactctt aaatgaagtc
    15421 ggtatcttct tagaagttta tgggcacaat actttcattt tgagggagca tcctatctgg
    15481 atgaaagaag aagagattgc atctggtgtc tatgaaatgt gtgacatgtt gcttctaacc
    15541 aatgaggtat ctatcaaaac ttaccgagca gagttagcta ttatgatgag ttgtaaacga
    15601 tctatcaagg caaatcatag cttggatgat tattcagcaa gaaatctgct actgcaattg
    15661 gcccaatgtc aaaatcctta taactgccct catggtagac ccgtattgat taattttagt
    15721 aaggcagata tggaaaaaat gttccgtcga attcaagaaa atcacactag cctgcgagag
    15781 ctaggaaaat attagagagg atgagatgca agagttttta aaccttccta agcagattca
    15841 gctgaggcaa ctggtacgct ttgtgaccat taccttaggc agtagtatct ttccctttat
    15901 ggccatgtat tatacgactt actttggtac gttttggaca ggcctcttaa tgatgattac
    15961 cagtttgatg ggatttgttg gaactttata cggtgggcat ctgtcagatg ctcttggtcg
    16021 taaaaaagtc attatgattg ggtcagtagg aacaacgcta ggctggtttc tgactatttt
    16081 agctaatttg cctaatgcag ctattccttg gttaaccttt gcgggtattt tattggtaga
    16141 gattgcttct agtttttatg gtcctgccta tgaagctatg ttgattgatt tgactgatga
    16201 gagtaatcgt cgatttgttt acaccatcaa ttattggttt atcaatattg ccgtcatgtt
    16261 tggtgcaggg ctatctgggc ttttttatga ccatcatttt ttagccttgt tagtagcctt
    16321 attactcgtt aatgtacttt gttttggcgt tgcttactac tattttgatg agactagacc
    16381 agaaacacac gcttttgatc atggtaaagg attactggcg agttttcaga actaccgtca
    16441 ggtgtttcag gatcgtgcct ttgtcttgtt taccttaggt gccatctttt ctggtagtat
    16501 ctggatgcag atggataact atgtgccagt ccatttgaaa ctgtattttc agccaacggc
    16561 tgtgttaggt ttccaagtaa ctagttctaa aatgttatca ttaatggttt taactaatac
    16621 attgctgatt gtccttttca tgacagtagt aaataaatta acggaaaaat ggaaactatt
    16681 acctcagctt gtggttggtt ctttactatt tactctaggg atgctcttgg catttacctt
    16741 tacgcagttc tatgctattt ggctatcagt tgttttgtta acttttgggg aaatgataaa
    16801 tgttcctgct agtcaagtcc tacgtgctga tatgatggat cattcccaaa taggatctta
    16861 tacaggtttt gtgtcaatgg cacaacccct aggtgctatt ttggctagtc tactagtatc
    16921 tgtcagccat tttacaggtc ctttaggtgt gcaatgctta tttgtagtca ttgctttgct
    16981 agggatttat tttacggttg tttctgcaaa aatgaaaaag gtgtagtatg tacgattata
    17041 ttaaaggtca attgaccaaa attacggcaa aatacattgt cgttgaaaca aatggactag
    17101 gctatattat caatgtagcc aatccttata gctttacaga tagtgtcaac caactggtaa
    17161 ctatttacct gcatcaagtg attcgtgagg atgctcactt gttgtttggg tttcatacgg
    17221 aagacgaaaa agatgttttt ctgaaattaa tttctgtatc tggcattggc cccacaacag
    17281 ctcttgctat tgtggcagtt gatgataatg agggacttgt gaatgccatt gataacagtg
    17341 acattaagta cctaatgaaa tttcctaaaa ttggtaaaaa aacagcgcag caaatggttc
    17401 ttgacttagc tggcaaattt gtggaggctc cacaagagac tggtaatacc aaagcgcgca
    17461 gcaataaagc aggcaatact caactggacg aagcgattga agccctcctt gccctcggtt
    17521 ataaggcaac ggaattgaag aaaattcgtg ccttctttga aggaacctct gagacggcag
    17581 agcaatacat caaatcagca ttgaaactgt taatgaaagg gtaggtgttt cacatgaaac
    17641 gttgctcatg ggttcctaag gataaccagc tttactgtga ttaccacgat ttagaatggg
    17701 gtcaacccct ggatgatgat agagattttt ttgaattgct gtgccttgaa agttaccagt
    17761 caggcttatc ctggctgact gttttgaaaa aacgccaagc tttcagaact gtttttcatc
    17821 attacgacat tgcatcggtt gcaaccttta cctcggagga aatagctgat gctttagaga
    17881 atccatccat catccgccac aagctaaagc tagcagcaac tgtcaacaac gctatcgcag
    17941 tacagaaaat tcaaaaagag tttggtagtt tttcaactta tctctggaat tttgttgggg
    18001 gaaagccaat taacaacctt gtcaatcaag agaatcttgt tccttctcaa acagaattat
    18061 ctattcgctt agctaaggat ttaaagaaaa gaggatttaa atttttaggg cctacaacgg
    18121 tttattcttt tatgcaagca tcgggtctgg taaatgacca tgaagaggct tgtgttttca
    18181 atagaatctt ctaattcttc gtgaattgga agattttttg ataaaataag atcagattac
    18241 gaatagataa gtaggtgggg aaatgaaagc tgaactgatt gcagtaggta ccgaaatttt
    18301 gactggtcaa attgtgaata ccaatgctca atttctgtcg gaaaaaatgg cagagctagg
    18361 tattgatgtc tattttcaaa cggctgttgg ggacaacgag gagcgtttac tttcagtgat
    18421 tacaactgct agtcagcgta gtgacttggt gattttatgt ggtggccttg gtccaacgaa
    18481 agatgattta accaaacaaa ctttagcaaa gtaccttagg aaagacttgg tttatgatga
    18541 gcaagcttgt cagaaactag atgacttttt tgctaagcgc aagccttcat cacggacacc
    18601 aaataatgag cgacaggcac aagtgattga agggtcaatc cctttgccaa ataaaactgg
    18661 tcttgcggtt ggtgggttca tcacagtcga tggtattagt tatgttgtct taccgggtcc
    18721 tccaagtgaa ttgaagtcga tggtaaatga agaattggta ccacttctgt caaaacaata
    18781 cagtacattg tattcaaagg tactacgctt ttttggtgtt ggggaaagtc agttggtaac
    18841 agttttgtca gattttattg agaatcaaac tgatccaact attgctccgt atgctaagac
    18901 tggcgaagtg actcttcgct tatcaacaaa aactgaaaac caagctctgg cagataaaaa
    18961 gttaggtcag ctagaagcgc agctactatc ccgaaaaact cttgaaggtc aacccttagc
    19021 tgatgtcttt tatggctatg gggaggataa ttccttagcg cgtgagacat ttgagctctt
    19081 agtaaaatat gataagacaa ttacagcagc agaaagtcta accgcgggat tatttcagtc
    19141 aactttggcg agttttccag gagcttctca agtattcaat ggaggctttg tggcttatag
    19201 catggaagaa aaagcgaaaa tgctaggcct tcctttagag gagttgaaat cgcatggcgt
    19261 tgttagtgct tatacagccg aggggatggc ggagcaagca aggttattga ctggtgctga
    19321 tattggggta agtttaacag gtgttgccgg accagatatg ttggaggaac agcctgcagg
    19381 tacagttttc attggccttg ccactcaaaa taaggtagaa tcaataaagg ttttgattag
    19441 cgggcgaagt cgtttggatg tgcgctatat cgccacttta catgccttta atatggtccg
    19501 taaaacttta ttaaaacttg agaatttgct ataatgttat ttagtagcta tagtaggata
    19561 tggtttacaa ttatgtagat taatcctgct gacgatggtt tgttaaaaaa gaggagaaag
    19621 tattggcaaa aaaattaaaa aagaatgaag aaatcactaa gaagtttggt gacgaacgtc
    19681 gcaaagccct tgatgatgct ttgaaaaata ttgaaaaaga ttttggtaag ggcgcagtga
    19741 tgcgattagg agaacgtgca gagcaaaaag ttcaggttat gagttcagga agtctagctc
    19801 ttgatattgc gcttggagct ggtggttatc ctaaaggacg tatcatcgaa atctatggtc
    19861 cagagtcttc cggtaaaacg actgtggctt tacatgctgt agcacaagct caaaaagaag
    19921 gtggaatcgc agcctttatc gatgccgagc atgcgcttga tccagcttat gctgctgcgc
    19981 ttggggttaa tattgatgaa ctcctcttgt ctcaaccaga ttctggagaa caaggacttg
    20041 aaattgcagg taaattgatt gattctggtg cggttgatct ggttgttgtc gattcagtag
    20101 cagctttagt gccacgtgct gaaattgatg gtgatattgg cgatagccat gtcggattgc
    20161 aagcacgtat gatgagtcag gccatgcgta aattatcagc ttctattaat aaaacaaaaa
    20221 ctatcgctat ctttattaac caattgcgtg aaaaagttgg tgtgatgttt ggaaatcctg
    20281 aaacaacacc aggtggtcga gctttgaaat tctatgcttc tgttcggctg gatgtgcgtg
    20341 gaacaactca aattaaagga actggtgacc aaaaggatag cagcattggt aaggagacca
    20401 aaatcaaggt tgttaaaaac aaggtcgctc cgccatttaa ggtagcagaa gttgaaatca
    20461 tgtacgggga aggtatttct cgtacagggg agcttgtgaa aattgcttct gatttggaca
    20521 ttatccaaaa agcaggtgct tggttctctt ataatggtga gaagattggc caaggttctg
    20581 aaaatgctaa gcgttatttg gccgaacatc cagaattgtt tgatgaaatc gaccgtaaag
    20641 tacgtgttaa atttggtttg cttgaagaaa gcgaagaaga atctgctatg gcagtagcat
    20701 cagaagaaac cgatgatctt gctttagatt tagataatgg tattgaaatt gaagattaaa
    20761 aagagccctt cagggctttt taaaatgtat ttttaaaggt tagtaggact actgttcata
    20821 ggtgtgtggg tgaatagaaa ccatcattta aaaagatgtg agaaagcaga aattaggata
    20881 actgatataa aattaaaata actgataatt caagggaata caggtgaaag accttatttt
    20941 accaagataa tatctttaaa attaaaaaaa taggtccaaa gacctatatt tatagataag
    21001 aaactgtgct acaataaagc tatcacgaaa tagaaagtga gtcagcaaca tgattaaaat
    21061 ttacacgatt tcaagttgta cgagctgcaa gaaagccaaa acttggctaa atgcccataa
    21121 gcttgcttat aaagaacaga acttaggaaa agaaccgcta actaaagaag aaattttagc
    21181 aattttatca aaaaccgaaa atggagtgga gagcattgtt tcatctaaaa accgttatgc
    21241 caaagctctc gattgcgata ttgaagaatt aagtgttagt gaggttattg atttgattca
    21301 agataacccg cgcatcctta aaagtcccat tttgattgat gataaacgtc tgcaagtagg
    21361 ctacaaagaa gacgatattc gtgctttttt acctcgctct attcgtaata ttgaaaatac
    21421 tgaagcacga ttacgtgctg cgctctaaaa gctcttgtag agcttttttt aaataccttc
    21481 ttcgcttgaa attcttgttt atttaataga aataagctat aataaagcat agcacttaat
    21541 tttagaaaga aggtgtaagt atgggattta cagatgaaac agtccgcttt aagttggatg
    21601 atggcgacaa acgacaaatt agtgaaacat taacagcagt ctatcattca cttgatgaaa
    21661 aaggttataa tccaattaat caaattgttg gttatgtctt gagtggggac ccagcttatg
    21721 ttcctcgtta taatgatgct cgaaatcaga ttcgtaaata tgaacgtgat gaaattgtag
    21781 aagaacttgt tcgctactat ttacaaggaa atggaattga tgttaaatga gaataatggg
    21841 acttgatgtt ggctcgaaaa cggttggtgt agctattagt gatcctcttg gctttacagc
    21901 ccaaggactt gaaattatca agattgatga ggaaaaagca gaatttggct ttacacgttt
    21961 agaagagctt gttaagcagt accaagttga acagtttgtt attggattgc caaaaaatat
    22021 gaataacacc aatggtccac gtgttgatgc aagtataact tatggaaacc acatagagca
    22081 cctttttgga cttccagtcc attatcaaga tgaacgattg acgactgttg aggcagagcg
    22141 tatgcttatt gagcaagctg acattagtcg tggtaagcga aaaaaagtca ttgataaatt
    22201 agctgcacaa ctcattttac agaactattt aaatcggaat ttttaaggag ataaaaaatg
    22261 acacataatc atgaaaatga ccaccaacac gaagttatca cacttgtgga tgaacaagga
    22321 aatgaaacct tgtttgaaat tttattaaca attgatggtc gtgaagagtt tggtaaaaat
    22381 tatgttctct tggttccagc gggatctgaa gaagatgagt ctggtgaaat tgaaatccaa
    22441 gcctattcat ttactgaaaa tgaagatggt actgaagggg atttacaacc gattcctgag
    22501 gattcagatg ctgaatggga tatgattgaa gaggtattta atagttttct agatgagaac
    22561 taaattgtta gtgacactat gttaaaaagt agccgtgagg gctatttttt taatgttatt
    22621 ttcgaataaa taagcaggag gtgataatga taaaagaatt aaatgataaa tttattaata
    22681 attataaggc taaacctttg cat
//
LOCUS       DAUGUF010000032        20142 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUGUF010000032 DAUGUF010000000
VERSION     DAUGUF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20142
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.032"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            46..1242
                     /locus_tag="VIB71_001339"
     CDS             46..1242
                     /locus_tag="VIB71_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ8823073.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINVLLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPASPSARPQVSYSSVNNYPVGQCTWGAKSLAPWAGNNWGNGGQWAASAQAAGYS
                     VGSTPMVGAIAVWNDGGYGHVAVVVEVQSSSNIRVMESNYSGKQYIADHRGWFNPTGV
                     TFIYPH"
     gene            1495..2457
                     /locus_tag="VIB71_001340"
     CDS             1495..2457
                     /locus_tag="VIB71_001340"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ8823074.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGLQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            2643..3398
                     /gene="recO"
                     /locus_tag="VIB71_001341"
     CDS             2643..3398
                     /gene="recO"
                     /locus_tag="VIB71_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEQ8823075.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            3501..4508
                     /gene="plsX"
                     /locus_tag="VIB71_001342"
     CDS             3501..4508
                     /gene="plsX"
                     /locus_tag="VIB71_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEQ8823076.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            4501..4743
                     /locus_tag="VIB71_001343"
     CDS             4501..4743
                     /locus_tag="VIB71_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ8823077.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHLAIPDEDVEDMVFMGDVLDYLVQRLT"
     gene            4894..5598
                     /locus_tag="VIB71_001344"
     CDS             4894..5598
                     /locus_tag="VIB71_001344"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEQ8823078.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVIAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            5722..9447
                     /locus_tag="VIB71_001345"
     CDS             5722..9447
                     /locus_tag="VIB71_001345"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEQ8823079.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAVSSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYKADDFTAYKVEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRAGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNDETIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARITSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNAYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKILSPEFKAAGENIYYIPGQAISEDIDFDLIKANFSQFEAIQTQHKIT
                     AASAVKYGGVLESFALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            9608..11062
                     /locus_tag="VIB71_001346"
     CDS             9608..11062
                     /locus_tag="VIB71_001346"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEQ8823080.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDRGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTVRKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAADEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            11090..12112
                     /locus_tag="VIB71_001347"
     CDS             11090..12112
                     /locus_tag="VIB71_001347"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEQ8823081.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVRAALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            12280..12834
                     /gene="purN"
                     /locus_tag="VIB71_001348"
     CDS             12280..12834
                     /gene="purN"
                     /locus_tag="VIB71_001348"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEQ8823082.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLTGYMKIVGETLLLAYEGRIINIHP
                     AYLLEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            13018..14565
                     /gene="purH"
                     /locus_tag="VIB71_001349"
     CDS             13018..14565
                     /gene="purH"
                     /locus_tag="VIB71_001349"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEQ8823083.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(14623..15747)
                     /locus_tag="VIB71_001350"
     CDS             complement(14623..15747)
                     /locus_tag="VIB71_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ8823084.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            16000..17265
                     /gene="purD"
                     /locus_tag="VIB71_001351"
     CDS             16000..17265
                     /gene="purD"
                     /locus_tag="VIB71_001351"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEQ8823085.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGAPIVVKADGLAVGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVKPVLEGMIAEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGVKFAENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDPTGLFYRNDIGSKAIRE"
     gene            17543..18034
                     /gene="purE"
                     /locus_tag="VIB71_001352"
     CDS             17543..18034
                     /gene="purE"
                     /locus_tag="VIB71_001352"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEQ8823086.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            18021..19094
                     /gene="purK"
                     /locus_tag="VIB71_001353"
     CDS             18021..19094
                     /gene="purK"
                     /locus_tag="VIB71_001353"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEQ8823087.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPANDCPAARV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSAGQLPQGTDLLRISQNR
                     IVEKDFLTNKAGVTVAPYKVVTSSLDLEGLDLTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGQDVTVFPVQENIHRNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVTENPSAHLHMYGKLE
                     AKHNRKMGHVTVFAEDADEVEEF"
     gene            19115..>20142
                     /locus_tag="VIB71_001354"
     CDS             19115..>20142
                     /locus_tag="VIB71_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823088.1"
                     /translation="MELREFKAWLLKNHFEEDELYKESIKCYQVEAYKAAYIFSYLAN
                     HKFIAKLAIDYSGVPSNFMSKCPDDEVRKSSWQKRVNSLKNEDEWEQTVNEKLIQAWE
                     GDNVFKLPFKIKEKYSHMRVLRNNAAHAKDCRISESTVLELWNEIEYIYPYFVINGTI
                     DAWMEDLEKLVRYSNSSIESQNQLQNKFGDFSTENKTLIVKKIIQKYLVDSEWDETYP
                     DIVMNFLLYIFQESNYINQIGKDLTEKEELYLSIGTGIYHFQAEAIDIYSQFEESLSD
                     YTFRYFCEEFSDNFWKFIDSMDSEVNKENLTATSLEILKKNSAILVNAEFNESRFLSD
                     NSLFFKSV"
BASE COUNT         5999 a         3694 c         4564 g         5885 t
ORIGIN      
        1 ggtaaaatat aagatgtctt atcgaaaagg agtagttttt ttattatgaa aaaaagaatt
       61 ttatcagcag ttcttgtaag tggtgttacc ctcggagcag ctacaactgt aggagcggag
      121 gatttaagta ctaagattgc taagcaagat tctattatct caaatctgac tacagagcaa
      181 aaagctgcac agaatcaagt ttcagcgtta caggctcaag taagttcact acaatctgaa
      241 caagataaac tgaccgcaag aaatacagaa cttgaggcgc tttcaaagcg atttgagcaa
      301 gaaattaagg ctctaacaag tcaaattgtt gctcgtaatg aaaaattaaa aaatcaagct
      361 cgtagtgctt ataaaaacaa tgaaacttct ggttatatta atgtactttt gaattctaaa
      421 tcaatttctg atgttgtaaa ccgtttagta gcaattaata gagctgtctc tgctaacgct
      481 aaattgttag aacaacaaaa agctgataaa gtttcccttg aagaaaagca agctgctaac
      541 caaacagcta ttaataccat tgccgctaat atggcaatgg ctgaagaaaa ccaaaataca
      601 ttacgtactc aacaagctaa tttggtagct gcaactgcaa atttagctct ccaattagca
      661 tctgctactg aagataaagc taatttggta gctcaaaaag aagctgcaga aaaagctgct
      721 gctgaagcct tagcacaaga acaggctgct aaagttaagg cacaagaaca ggctgcacaa
      781 caagcagcat ctgttgaagc agcaaaatct gctattactc cagcaccaca agctactccg
      841 gcagcgcaaa gtagtaatgc tattgaacca gctgcactca cggctccggc atctccttct
      901 gcaagaccac aagtttcata tagttctgtt aataattacc cagtaggaca atgtacatgg
      961 ggtgcgaaat cattagctcc atgggcagga aacaattggg gtaacggtgg acaatgggct
     1021 gcaagcgctc aagcagcggg ctactctgta ggatctacac ctatggtagg agctattgcg
     1081 gtttggaatg atggcggtta tggtcacgtc gcagtagttg ttgaagttca aagttcatca
     1141 aatattcgag tgatggaatc aaactacagt ggtaaacagt atattgctga ccaccgtggt
     1201 tggtttaatc caacaggtgt tacatttatt tatccacact aacatattat ttaggttaga
     1261 acagttgttc taaccttttt gattactcct attgtggaat agttctgaga gtattgacga
     1321 tatggttaat ttataagaga gttgtttggc caatcgctta tgtataatat aagagaagta
     1381 tataaagtcg ataaaaggta tatttaatac attctttaac ggtttttcaa tttcatttga
     1441 taattcactt gaaaagcgtt aaaatggtat aggattaaaa ctttggagga aaaaatgtct
     1501 tattctgatt taaaattgtt tgctttatcg tcaaacaagg aattagcaga aaaagttgcg
     1561 tctgcaatgg gtcttcaact tggaaagtct acggttcgcc agttttcaga tggtgaaatc
     1621 caagtaaata ttgaagaatc aattcgtggt catcatgtct ttattttgca atcaactagc
     1681 tcacctgtca atgacaattt aatggaaatt ttgattatgg tcgatgcttt aaagcgtgct
     1741 agtgctgaaa aaatttcagt tgtgatgcct tactacggct atgcacgcca agaccgtaaa
     1801 gcgcgttctc gtgaacctat tacttcaaaa ttagttgcta atatgttaga agttgctggt
     1861 gtagatcgct tattaacggt tgatttacat gctgctcaaa ttcaagggtt ctttgatatt
     1921 ccagttgatc acttgatggg tgcaccttta attgcagact attttgatcg tcatggttta
     1981 gtgggtgaag atgttgtcgt tgttagtcct gaccatggtg gtgtgactcg tgcgcgtaaa
     2041 ttagcacaat tcctccaaac accaattgca attatcgata agcgtcgtag tgtggataag
     2101 atgaacacca gtgaagtgat gaatattatc ggaaatgttt cgggcaagaa atgtatcttg
     2161 attgacgata tgattgatac cgcagggact atttgccatg cagcagatgc gcttgctgaa
     2221 gcgggggcaa cagctgtgta tgcgtcatgt acgcatcccg ttctttctgg accagcactt
     2281 gataatattc aacgttcggc tatcgaaaaa ctaattgttc ttgatactat ttatctgcca
     2341 aaagaacgcc ttattgataa aattgaacaa atttcaattg ctgatttggt tgcagaagcg
     2401 attattcgca ttcatgaaaa acgtccgttg tcacctttat ttgagatggg caattaaact
     2461 taacgaagcc tgagataata gatctcaggc tttttgactt gaataaaatg taagggtaat
     2521 gtggtattaa ttattgtggg atgaactatg caattctaaa ggattttggg tataataaga
     2581 aagataacaa cagtttattg taaactaaga taaaaggtaa gagaaaaata cgacgaggta
     2641 atatgcaact aacagaatca ctaggcatcg ttctttttaa taggaattat cgagaagatg
     2701 ataaattagt caaaatattt actgaagtag caggtaagca gatgtttttc gtgaaacata
     2761 ttagtcgttc caaaatgtcc tcaatcattc aaccactaac gattgctgat tttattttca
     2821 agttaaatga tacaggcttg tcttatgttg ttgactatag taacgttaac acttatcggt
     2881 atattaataa tgatattttt cgattagcct atgctagtta tgtcttagca ttagctgatg
     2941 ctgcgattgc agataatgaa tcagattcgc atttgtttac gtttttgaaa aaaacacttg
     3001 atttgatgga agagggccta gattatgaaa ttttgacaaa tatttttgaa attcagatat
     3061 tagatcgttt tggtattagt ctaaactttc atgagtgtgc catttgtcat cgcactgatt
     3121 taccgcttga tttttcccat cgtttttcag ctgtactttg ttctgaacat tattacaaag
     3181 acaaccgacg taatcattta gatccaaatg ttatctactt gttgagtcga tttcaaaaaa
     3241 tcacatttga tgatttgaga actatttcat tgaataaaga catcaaaaag aagcttcgtc
     3301 agttcattga tgagttgtat cacgactatg taggaatcaa attaaaaagt aaaacattca
     3361 ttgataattt agttaagtgg ggagatatta tgaaatgata gggcctcttt cgtttatggg
     3421 aattggtttc agaatatgct ataataaaaa tactattaat agattgtgta agaacacaag
     3481 atataattaa aggagtggaa atgaagagaa ttgcaataga tgctatgggt ggagataacg
     3541 ctcctaaagc tattgttgag ggtgttaatc aagcaataga agcattttca gatatcgaaa
     3601 ttcaacttta cggtgatcag acaaagatta actcctatct tattcaatca gatcgtgttg
     3661 ctattattca tacagatgaa aaaattatgt cagatgatga acctgcaaaa gctgttcgcc
     3721 gtaaaaagaa ggcttcaatg gttttagcag ctaaggcagt gaaagaagga aaagcagatg
     3781 ccattatttc agcaggtaat acaggtgctc ttttagctgt aggtttgttt gttgtggggc
     3841 gtatcaaggg agttgatcgt ccaggattat tatcaactat tcccacagta accggattag
     3901 gatttgatat gttggatctt ggagctaatg ctgaaaatac ggcaaaacat ttacatcaat
     3961 atgctatttt aggctctttc tatgctaaga atgtacgtgg gattgctaat ccacgtgttg
     4021 gtctattaaa caatggtaca gaagaaacaa aaggagatcc ccttcgtaag gccacttatg
     4081 aacttttaac agcagataat acaatatctt ttgttggtaa tgtcgaggcg cgagaactta
     4141 tgtcaggtgt tgcagatgtt attgtatcag atggtttcac gggaaacgca gtgttgaaat
     4201 caatagaagg aacagctatt agcattatgg ggcaactgaa acagataatt aatagcggcg
     4261 gtattaagac taaaattgga gctagtctac ttaaaagtag tctttacgag atgaagaaga
     4321 ctcttgacta ctctagtgct ggaggtgcag ttttatttgg tttaaaggca cctgttgtaa
     4381 agtctcatgg ttctagtgat gtaaaagcta ttttttcaac gataaaacaa gtacgtacga
     4441 tgctagacac taacgtggtc ggacaattag tagaagaatt tgctaaggag actcaagtaa
     4501 atgactagac aggagatttt tgaaaggctg attaacttaa ttcagaagca aagaagctat
     4561 ttgagtgtag ctattacaga acaaacacat ttaaaaaatg atttagcggt tgactctatt
     4621 gaactagttg aatttattat taatgttgaa gatgaatttc atcttgctat tcctgatgaa
     4681 gatgttgagg atatggtatt tatgggagac gttttagatt atttagttca gcgtttgact
     4741 tagttagaat aataaaaaga gcgtaagctc tttttattat tctttaaaaa cgaacctttt
     4801 tttaaaaaaa cttataaacg taaataatat cttgaatatt tttatagagt atgttactct
     4861 taaatgaaaa cagaaagaaa ggcgaataat caagtgacta accagcttat ttataaagga
     4921 aaagcgaaag atatttatag tacaaaagat gaaaatgtga ttagaacggt ctataaagac
     4981 caagctacta tgttgaatgg agctcgtaag gagactattg atggcaaggg agcactaaat
     5041 aatcagattt catctcttat ttttgagaaa ttaaataagg ctggtgtggt gacacattat
     5101 attgagcaaa tttcaaaaaa cgaacaattg aataaaaaag ttgatattat tccacttgag
     5161 gtggtgttac ggaatgtgat agcaggctca ttttcaaaac gttttggagt ggaagaagga
     5221 cgtgttcttg aaacgccaat tgtggaattt tactacaaaa atgatgatct gaatgatcct
     5281 tttatcaatg atgagcatgt gaagtttttg ggtattgtta atgatgagga gattgcttat
     5341 ctgaaaggag agactcgccg tattaatgaa ctcttgaaag gttggtttgc tcagattggg
     5401 cttaacttga ttgacttcaa gttggagttc ggatttgatc aagaaggtac aattatctta
     5461 gcagatgaat tttcgcctga taactgtcgc ctatgggata agaatggtaa ccatatggac
     5521 aaggatgttt ttagaagaga ccttggcaac ctgacggatg tctatcaagt tgtacttgag
     5581 aagttgatag cattgtaact agaagaggaa ggaattgaat ccgttcggga aactccgaaa
     5641 aaaagatgga acttactgaa atctcaattt cagatgtcct cctatttttc agtcgctccc
     5701 ttgtcggact tggtatctta tatgaataaa cgtatttttg ttgagaaaaa ggctgacttt
     5761 ggtattaaat cggctagcct tgtgaaagag ttgacgcata atctacaact gacttctttg
     5821 aaggctttgc gtattgtgca ggtctatgat gtcttcaatt tggctgagga tttgctggcg
     5881 cgtgctgaga agcatatttt ctctgagcag gtgacagact gtcttttgac ggaaactgaa
     5941 atcactgcgg agcttgataa ggttgccttc tttgccattg agtcgcttcc tggtcaattt
     6001 gaccaacgtg ctgttagttc gcaagaagct ttgctattat ttggaagtga cagtcaggtt
     6061 aaggtcaata cagcccagct ttacttggtc aataaggata ttgcagaagc agagcttgaa
     6121 gccgttaaga actatctttt gaaccctgtt gattcgcgtt tcaaggacat tactttgccg
     6181 cttgaagagc aggctttctc tgtgtctgat aagacgatcc ctaatcttga tttcttcgag
     6241 acttataagg ctgacgattt tacggcttat aaggtagagc agggcttggc tatggaggtc
     6301 gatgatcttc tcttcatcca agattatttc aaatcaatcg ggcgtgtgcc aactgagact
     6361 gagttgaaag ttttggatac gtattggtca gaccactgtc gtcacacaac ctttgaaact
     6421 gaattgaaga acattgattt ttcagcttct aaattccaaa aacaattgca gacaacttat
     6481 gacaaatata tcgccatgcg tgatgagctt ggtcgttctg aaaagccaca aacacttatg
     6541 gatatggcga ctatttttgg tcgttatgag cgtgccaacg gtcgtctgga cgatatggaa
     6601 gtctcagatg aaatcaatgc ctgctcagtt gagattgaag tagatgttga tggtgtgaaa
     6661 gagccttggc tcctcatgtt taagaatgag acacacaatc acccaacaga aattgagcca
     6721 ttcggtggag cggcgacttg tatcggtggt gctattcgtg acccattgtc aggacgttca
     6781 tacgtttatc aggctatgcg tatttcaggc gcaggcgata tcacgactcc gattgcggaa
     6841 acacgtgctg gtaaattgcc acaacaggtt atttctaaga ctgcggcgca cggctattct
     6901 tcatatggta accaaattgg acttgcgaca acttatgtgc gtgagtactt ccaccctggc
     6961 ttcgtagcca aacgtatgga gcttggagct gtggttggtg ctgcacctaa ggaaaatgtg
     7021 gttcgtgaaa aaccagaagc aggtgatgtg gtaatcttgc ttggtggtaa aacagggcgt
     7081 gacggtgtcg gcggtgcgac aggttcatct aaggttcaaa cggttgaatc tgtggaaaca
     7141 gcaggagcag aggtacaaaa agggaatgcc atcgaagagc gtaagattca acgtcttttc
     7201 cgtgctggca atgtcactcg tctgatcaag aaatcaaatg acttcggtgc aggtggtgtc
     7261 tgtgttgcca tcggtgaatt ggctgacggt cttgaaatcg atttggacaa ggtgcctctt
     7321 aaataccaag gtcttaatgg tactgaaatt gcaatctcag aatctcaaga gcgtatgtca
     7381 gtcgttgttc gtccaagtga tgtggatgcc ttcatcgcag cctgcaacaa ggaaaatatc
     7441 gatgcagtcg tagttgcgac tgtgactgaa aaaccaaatc ttgtcatgac ttggaatgat
     7501 gaaacaattg ttgatttgga acgccgtttc cttgatacca atggtgtccg tgtcgttgtt
     7561 gatgctaaag tcgttgacaa ggacttgaca gttccagaag cacgcataac atcagcagag
     7621 acacttgaag cagatacgct taaggtcttg tctgacctca accatgctag tcaaaaaggt
     7681 ctccaaacca tctttgactc atctgttggt cgttcaaccg ttaaccaccc aatcggtggt
     7741 cgttaccaaa tcacaccgac agaaagttct gttcaaaaat tgccagttca acatggtgtg
     7801 acaacaactg catctgttat ggctcaaggt tacaatgctt atattgcaga gtggtcacct
     7861 tatcacggtg ctgcctatgc tgttattgaa gcgacagctc gcttggtagc aacaggtgct
     7921 gactggtctc gtgcacgttt ctcttaccaa gagtatttcg agcgtatgga taaacaggca
     7981 gagcgttttg gtcagccagt atcagctctt cttggttcta ttgaggctca gattcaactt
     8041 ggcttgccat caatcggtgg taaggactct atgtctggta ctttcgaaga cttgacagta
     8101 ccaccaacct tggtagcttt cggtgtgaca acagcggaca gccgcaagat tctctctcct
     8161 gagtttaaag cggctggtga gaatatctac tacattccag gtcaagctat ttcagaagat
     8221 attgattttg accttatcaa ggctaacttc agtcagtttg aagctattca aactcaacat
     8281 aagattacag ctgcctcagc cgttaaatac ggtggtgtcc tagaaagttt tgctctcatg
     8341 acttttggta accgtatcgg tgcttctgtt gaaattgcag agcttgacag cagcttgaca
     8401 gctcaactcg gaggttttgt ctttacatca gctgaggaaa ttgctgacgc ggtgaaaatc
     8461 ggtcaaactc aggcagactt tacagtcact gtcaatggaa atgaccttgc tggcgctagc
     8521 cttctagcag ccttcgaagg caaattggaa gaggtttacc caacagaatt tgaacagaca
     8581 gatgttcttg aagaagttcc tgctgtggta tcagatactg ttatcaaggc taaggaaaca
     8641 attgaaaaac cagtggttta cattccagtc ttccctggta ccaactcaga gtacgattca
     8701 gctaaggcct ttgaacaggt tggagctagt gtcaacttgg taccatttgt aaccttgaat
     8761 gaggttgcta ttgctgagtc agttgacact atggttgcta atattgctaa ggcaaatatc
     8821 atcttctttg ctggaggttt ctcagcagcg gatgaaccag atgggtctgc taagtttatc
     8881 gtcaatatct tgcttaacga gaaggtccgc gcagctattg acagcttcat cgaaaaaggt
     8941 ggccttatca tcggtatctg taatggtttc caagcccttg ttaaatcagg tcttcttcca
     9001 tacggaaact tcgaggaagc tggtgagaca agtccaactc tcttctataa cgatgctaat
     9061 cagcatgttg ccaagatggt tgagactcgt atcgcaaata ccaactcacc ttggttggca
     9121 ggagttgagg tcggcgatat tcatgccatt ccagtttcac atggtgaagg taaatttgtt
     9181 gtcagcgctt ctgaatttgc agagctaaga gacaatggtc aaatctggag ccaatatgtg
     9241 gactttgacg gacaaccatc tatggattct aaatacaatc caaacggctc tgtcaatgcc
     9301 atcgaaggga ttaccagcaa gaatggtcaa atcatcggta agatgggaca ctcagaacgc
     9361 tgggaagacg gactcttcca aaatattcct ggtaacaaag accaaaccct ctttgcaagt
     9421 gctgtaaaat actttacagg gaagtaaaaa ggttcagtga acctttttag ccctcgcctt
     9481 gaattagtga agggcgaggt tagaaagaat ctcgcttaat ttttgagaaa tagtaaacac
     9541 gggcgataag ttgtgcgaaa aactttctat tttcgcttta cttgacagcc tttgtatcga
     9601 ggtaaaaatg acatacgaag taaaatctct aaatgaagaa tgtggagtct ttggtatctg
     9661 gggacatcct caggcagctc aagtcactta ctttgggctt catagccttc aacatcgcgg
     9721 tcaagaagga gctggtattg tttcaaatga caatgggaaa ctctatggtt atcgaaatgt
     9781 tgggctcctt tctgaagttt ttaagaatca atctgaatta gataatttaa ctgggaatgc
     9841 ggctattgga catgttcggt atgctactgc aggttctgca gatattcgca atattcagcc
     9901 ttttctttat aaatttcatg acgggcaatt tgctttatgc cataatggta atttgacaaa
     9961 tgctatttcc ttaaggaaag aattagaaaa gcaaggtgca attttcaatg cctcctcaga
    10021 tactgaaatt ttgatgcact tgattcgtcg aagccataac tcaagtttca tgggaaaggt
    10081 aaaagaagct ctaaatacag taaagggtgg ctttgcctat ctactgatga cagaaaataa
    10141 actcattgct gctcttgacc ctaatgcctt tcgtcctttg tcaattggac aaatgcaaaa
    10201 tggtgcctgg gttatttcca gtgagacctg tgcttttgag gtggtaggcg caaaatgggt
    10261 tagagatgtt gaacctggcg aagttattct tatagacgat cgtggtattc aatgtgatcg
    10321 ttatactgat gaaacgcaac tggcaatttg ttcgatggaa tatgtctatt ttgcaaggcc
    10381 ggattcaact atacatggtg ttaatgttca tacggttcga aaaaatatgg gaaagcgtct
    10441 tgcacaagaa tttaaacagg atgctgatat tgtaattggt gtcccaaatt cgtccttatc
    10501 ggctgctatg ggctttgctg aagaatccgg attaccaaat gagatgggtc ttgtaaaaaa
    10561 tcagtatacg cagcgaacct ttattcaacc gacacaagaa ttaagggaac aaggtgttcg
    10621 aatgaaacta tcagcggtat ctggtgttgt caaaggaaag cgcgttgtta tgattgatga
    10681 ctcaattgta agaggaacga cttctagaag gattgtcgga ttattaagag aagcaggagc
    10741 tagtgaagta catgttgcta tagctagtcc agaattaaag tatccttgtt tttatggtat
    10801 tgatattcaa acaagacgag aattaatttc agcaaatcac gctgctgacg aagtgtgtga
    10861 tattattggc gcagatagtc tgacctatct ctcactagat gggttgattg aatcaattgg
    10921 actcgaaaca aaagcaccaa atggtggttt atgcgtagct tactttgatg gacattatcc
    10981 aacaccgctt tatgattatg aagaagaata cctcagaagt ttagaagaaa aaacaagttt
    11041 ttatattcaa aaagtgaaat aagctctgct aattatataa ggagaaaaca tgtctgaaaa
    11101 aaatgcttat gcaaaatctg gtgttgatgt tgaagctggt tatgaagtgg ttgaaagaat
    11161 aaaaaaacac gttgctcgta cagaacgtgc gggagtcatg ggagctctag gtggctttgg
    11221 tgggatgttt gacttgagta aaacaggagt tagagagcct gttttggtct cagggacaga
    11281 cggtgttggc acaaaactca tgcttgctat caagtacgac aagcacgaca caatcggtca
    11341 agactgtgtt gccatgtgtg tcaatgatat tattgcagca ggtgctgagc ccctttactt
    11401 ccttgactac gtagcgacag gaaaaaataa tccagtcaaa tttgaagaag ttgtttctgg
    11461 cgttgcagaa ggttgtgttc aagcaggagc agcactcatt ggaggtgaga ccgctgaaat
    11521 gcctgggatg tatggcgaag atgattatga ccttgctggc tttgctgttg gtgtggctga
    11581 aaaatctcag ctcatcgacg gttcaaaagt aaaggaaggc gatattcttt tgggacttgc
    11641 ttcaagtggt atccattcaa acggttattc tttggtacgt cgtgtctttg ctgactatac
    11701 tggtaaagag ctgcttccag aacttgaagg aaaacaactt aaggatgtcc ttcttgagcc
    11761 aactcgtatt tatgttagag cagctctgcc attaatcaag gaagaactag tcaacggtat
    11821 cggccacatc acaggtggtg gctttatcga gaatgttcct cgtatgtttg cagatgattt
    11881 ggctgcggaa atcgatgagg acaaggtgcc agtgcttccg attttcaagg cgcttgaaaa
    11941 atatggtgac atcaagcacg aagaaatgtt tgaaatcttc aatatgggtg tcggtcttat
    12001 gctagctgtt agtcctgaaa atgttaaccg cgtcaaagag ctcttggatg aaccagttta
    12061 tgaaatcggt cgtatcatca agaaagcaga cgatagtgtg gtgattaaat aagtcactaa
    12121 attttataag aaaggagtgt ttagttagtt tgcctaactg aacacgggat taaatttcta
    12181 ggaaaaaaga taaaatgact tagacgcaag cgtcgttgtt cgttttccta tttttctacg
    12241 aaatttttcg gcaagccgaa tcatcccttt gtatcgaata tgaaaatcgc tgtttttgct
    12301 tctggtaatg gttccaactt tcaggtcata gcagagcagt ttccagttag ttttgtcttt
    12361 tcagatcatc gtgatgccta tgttttagag cgtgctcaga atttagccat tccaagcttc
    12421 gcttttgaac tcaaggagtt tgagaataag gcggcttacg agcaagccat cgttgatttg
    12481 ttggacaaac acgagattga tttggtctgt ctaacgggct atatgaagat tgttggagaa
    12541 accttactct tggcctatga ggggcgtatt atcaatattc acccagccta cctgcttgaa
    12601 tttccaggtg cccacggtat cgaggatgct tgggaagctg gtgttgacca gtctggcgtg
    12661 accatccact gggttgactc tggtgtggat accggtcagg tcatccaaca agtgcgcgtg
    12721 ccacgcctag cagacgatag cctagaaagc tttgaaaccc gtatccatga aaccgaatat
    12781 caactctacc cagctgtctt agatagcttg ggagtggaga ggaaagtaat ctagccttta
    12841 tcttaaaatt ttaggtaaag ttaggaaaga tagtaaagaa gaattaacgt tccaaaaaga
    12901 aaggaattga acccgtctgg aaggcacaga aaaaagataa acatctccta ggcgcaagcg
    12961 tcttcgtcga gtttcctatt tttccttggc cttctagtcg gacttggtat cttaaatatg
    13021 actaaacgtg ctttaatctc agtgtctgac aagtcaggaa ttgttgactt tgcaaaagaa
    13081 ttgaaaaact tgggttggga tattatctca actggtggga ctaaggttgc ccttgataat
    13141 gctggcgttg agaccattgc catcgacgat gtgactggat tcccagagat gatggacggt
    13201 cgtgttaaga ccctccaccc aaacattcac ggtgggcttt tggctcgtcg cgacgctgac
    13261 agccaccttc aggctgctaa ggacaacaat atcgagctga ttgacctcgt ggttgtcaac
    13321 ctctatccct tcaaggagac tatccttcgt ccagatataa cctatgattt ggcggtggaa
    13381 aacatcgaca tcggcggtcc atcaatgctt cgctcagccg ctaaaaatca cgctagcgtg
    13441 accgttgtgg ttgacccagc ggattatgcg actgttttgg gagaattggc tgacgctggt
    13501 cagacgacat ttgaaacgcg tcaacgcttg gcagctaagg tctttcgtca cacagcagcc
    13561 tacgacgctt tgattgctga gtacttcaca actcaagtgg gagaggctaa gcctgaaaaa
    13621 ttaaccatca cttacgacct taaacaggct atgcgttacg gagaaaatcc acaacaagac
    13681 gctgatttct atcaaaaagc cttgccaaca gactactcaa ttgcttctgc taaacagctc
    13741 aacggaaaag aattgtcctt caataatatc cgtgatgccg atgcagcaat ccgtattatc
    13801 cgtgatttca aagatcgtcc aactgttgtt gtcctcaaac acatgaaccc atgtggtatc
    13861 ggacaggctg atgatattga gacagcttgg gattacgctt atgaagctga cccagtttca
    13921 atctttggtg gaattgtcgt ccttaaccgt gaagttgacg cagcgacagc taagaagatg
    13981 caccctatct tcttggaaat catcatcgca ccatcatact cagaagaagc gctagctatt
    14041 ctcacaaata aaaagaaaaa cttgcgaatc cttgagttgc cgtttgatgc ccaagctgcc
    14101 agcgaagtgg aagctgagta cactggcgta gttggtggac ttttggtgca aaaccaagac
    14161 gttgtggctg aaaatccatc tgactggcaa gtggtgacag accgccaacc aacagaacaa
    14221 gaggcgactg cccttgagtt tgcctggaag gctatcaagt atgttaagtc taacgggatt
    14281 attattacta acgatcacat gacgcttgga ctcggtgcag gtcaaaccaa ccgtgtcggc
    14341 tcagtcaaga ttgctatcga gcaggctaaa gaccaccttg acggtgccgt tctagcatca
    14401 gatgccttct tcccatttgc ggacaacatt gaagaaatcg ctgccgcagg gatcaaagca
    14461 atcatccaac caggtggttc agttcgtgac caagactcta ttgacgccgc aaacaaacat
    14521 ggcttgacca tgatcttcac aggtgtgaga cattttaggc attaataaaa aaatgtggtc
    14581 taattaaaac cacatttttt attaaaagaa aatataagtt aactataatt tgttagcttt
    14641 atcagcattt acccatgttc cacgagatcc gatttgaaca taaataccat tacttggttg
    14701 atcaattttt aatactttat aactaccagt gacggtaaaa tattcaccca cacggagaat
    14761 ttgatctcct aaaacttttc cttggttatc tgtttcatct aatggtgtgg gatcaatcca
    14821 gtttagtgga gttgggtctc ctccggctaa ttctttatta acgatcaaat tattaacaag
    14881 ctgatctaca cgaaaaacgc cagggaaggt aacagtatca ccgaccttaa tggaaggttt
    14941 tgtattgtca ttttgaacca cagactgtgc gggctcttta atgggaatat agcgtcggtt
    15001 tccagaaaaa ctgaggtagc taagccatgt ataacctcca gcagtcacga ctttatcgta
    15061 ataaacagat tgacctgctt catagtaagc aagatcaggg ctatcgatac tggtttgtcc
    15121 tttgactggt aatctggttg taaagtgata agttccagag gggtcaaatg aagcttgaga
    15181 aatgtgtttt agttgtcttg ggtaggaatg acttgtctga gatgataagt ctttaaaatg
    15241 gatataacca cttacctgag attttggaat ttgacgctta tggtatcttt cagggccttg
    15301 tccagcgttg taattatact cttcgatagt gacagtgtct ccacggatat cagctaccca
    15361 tgctacatga ccgtaagcag catttgactg ataagcgttt ttatcaaacc aagcgatagc
    15421 ccctatgctt ggtgtcttat tcacaggata accctgattt ttcgcgatat gtccccacgt
    15481 gcaggcatta ccgtagcctt taggtaactg aaaaccatta gcagagctta aacgaaaagc
    15541 tgcaaaagaa gtgcattggc ggatatacat gttccacgaa tcgattccat tgcctttttt
    15601 ccacttactc ggatagttat cgcctaaaac agctgcatga acaagatttt cctgttgcga
    15661 aataagtgta gatggcatag taggtactag accattaaaa cctaaaagga ttactcctga
    15721 gaccaaaaaa cgatgaaatt ttttcattaa ttacctcctg taacttatta ttcgaaagca
    15781 agaaacaaaa aatgttattt ttagatgatt attttgaaaa ttggctttac ttgatattaa
    15841 ataactgttt gattggctaa tagagtgttc cttatttcaa gaattgtggt ctactatcac
    15901 atttttacaa tgtttcaatt attgataact aatacattat gtaaaaaagc gaacgtttat
    15961 gatataatat ctaattataa tacgaaagag gtggatgttt tgaaattact tgttgttggt
    16021 tcaggtggtc gtgaacatgc gattgctaag aagttgttag cgtctaaggg tgtggatcag
    16081 gtttttgtgg cacctggtaa tgatggtatg accttggatg gtctggactt ggtgaatata
    16141 gtagtttccg aacattccag gttgattgcc tttgctaagg agaatgagat ttcttgggcc
    16201 tttattggtc ctgatgatgc gctagcagct ggtatcgttg atgatttcaa cagtgctgga
    16261 ctcagagctt tcggtccaac aaaggcagca gcggagctag agtggtcaaa agactttgcc
    16321 aaggaaatca tggtcaaata caatgtccca acagcagcct atggcacatt ttcagacttt
    16381 gaaaaagcca aagcctacat cgaagagcag ggcgcaccta tcgtggtcaa ggctgatggc
    16441 ttggcggtag gtaagggtgt ggtcgtggct gaaaccgttg agcaggcggt agaggcggcg
    16501 caagagatgc ttctggacaa taagtttggc gattcaggag cgcgtgtggt tatcgaggaa
    16561 ttcttggatg gcgaggagtt ttccctcttt gcctttgtta atggtgataa gttctacatc
    16621 atgccgacag ctcaggatca caagcgtgcc tttgacggag acaaggggcc aaacactggt
    16681 ggtatgggtg cctatgcgcc agttcctcat ctacctcaga gcgtggtaga cacagcggtt
    16741 gagacgatcg ttaaacctgt ccttgagggt atgattgccg aagggcgtcc ttatctaggc
    16801 gtcctctatg cgggacttat cctgacggct gatggtccta aggttatcga gttcaactca
    16861 cgtttcggtg accctgaaac tcagattatc ctccctcgcc tgacttccga tttcgctcag
    16921 aatattgacg atatcatgat gggcattgag ccttacatca cttggcagaa ggacggtgtg
    16981 actttgggtg ttgtcgttgc ctcagaaggc tatccactcg attatgagaa aggtgtgcca
    17041 ctgcctgaaa agaccgacgg tgatatcatc acctactacg caggagttaa gtttgcagaa
    17101 aatagcgagc tacttctctc aaacggagga cgtgtctata tgctcgtcac cacagaagac
    17161 agcgtcaaag cagggcagga caaaatctat acccaactgg cccaacaaga cccaacaggt
    17221 ctcttctacc gaaatgacat cggaagcaaa gctataagag aataagacta accattcaaa
    17281 tattagcgtc agcaatcaac gaccgaaggt cgctccaaaa agaaagaaga aaggaactga
    17341 acacgggact aatttcctag gaaaaaaata aaactacctg gacgcaagca tcatcgttag
    17401 ttttctgcgt cgtaggcgtc tgatgctaaa gcacctagtc gccctgacgt aggttcgtct
    17461 tcgaaatcaa agatttcgga cttaccgcat atttttctac ggaaagtttc gacaagtcga
    17521 aacgcccctt tgtatcttaa ttatgaaaac tccaattatt tctattatca tgggctccaa
    17581 atctgactgg gcaaccatgc aaaaaacggc tgaagttcta gacaactttg gcattgctta
    17641 cgagaagaaa gtcgtctctg ctcaccgcac gcccgacctc atgttcaagc atgctgagga
    17701 agcacgtggt cgtggcatca aaatcatcat cgcaggagca ggtggggcag ctcacttgcc
    17761 tggtatggtg gcagctaaaa caacgctgcc tgttatcggt gtgcctgtca aatcacgtgc
    17821 cctttcaggt ttggattcac tctattcgat tgtgcagatg cctggcggtg tgcctgtggc
    17881 aaccatggct atcggagaag cgggagcgac taacgctgcc ctgacagccc tccgtattct
    17941 ctccatcgag gatcaaaatc tggctgatgc gctagctcat ttccatgagg aacaaggaaa
    18001 aatcgcagag gagtcaagtg gtgaactcat ttaagaccat tgggattatc ggtggtggtc
    18061 agctggggca gatgatggcg attgcggcta tctacatggg ccataaggtc atcacgctgg
    18121 atcctgctaa cgactgtcct gccgcccgcg ttagcgaggt gattgtggca ccttacgatg
    18181 atgttgaggc tttgggacaa ttagctgcgc gttgcgatgt tttgacctat gagtttgaga
    18241 atgtcgatgc cgatggtctg gatgccgttg tgtcagctgg tcagctaccg caggggactg
    18301 atctgctccg catttcccaa aaccgtatcg ttgaaaaaga ctttctgaca aataaggctg
    18361 gtgtgactgt cgctccttat aaggtggtga cgtctagcct tgacctagag gggcttgatt
    18421 tgaccaagac ctatgtcctc aagacagcga caggtggtta tgacggtcat gggcaaaagg
    18481 ttattcgctc cgcagaagac ctaccagagg cgcaacaatt agccaactca gctcagtgtg
    18541 tcttggaaga gtttgtcaat tttgaccttg aaatctcagt tatcgtgtct ggaaatggtc
    18601 aggatgtgac ggtctttccc gttcaggaaa atatccaccg caataatatc ctgtcaaaaa
    18661 ccatcgtgcc agctcgtatc tcagatcaac tggctgataa ggctaagaaa atggcggtgc
    18721 agattgccaa gaaactccag ctgtcaggaa ctctctgtgt ggaaatgttt gcgaccgcag
    18781 atgatatcat tgtcaacgaa attgccccac gtccccacaa ctcagggcac tactcaatcg
    18841 aggcttgcga cttttcacag tttgacaccc acattttggg cgtgctagga gcgccgctcc
    18901 caaccatcca cctccatgct ccagccgtca tgctcaatgt cctcggacaa cacgtccagc
    18961 aggcgattga ctatgtgact gaaaacccta gcgcccacct ccacatgtat ggtaaactag
    19021 aagcgaaaca taaccgcaaa atgggacacg tgacggtgtt tgcagaagat gcggatgagg
    19081 tggaggagtt ttagaacagg agtagattgg taagatggag ttaagggaat ttaaagcgtg
    19141 gttattaaaa aaccattttg aagaagatga gttatacaag gaatctataa agtgttatca
    19201 agtggaagca tataaggctg cctatatttt ttcgtattta gcaaatcata agttcattgc
    19261 taaattagct attgactaca gtggtgtccc atcaaatttt atgtctaaat gtcccgatga
    19321 tgaagttaga aagtcgagtt ggcaaaaacg tgtgaattcc ttaaaaaatg aagatgagtg
    19381 ggagcagacg gttaacgaaa aattaattca agcatgggaa ggtgataatg tattcaaatt
    19441 acctttcaaa attaaagaaa aatattctca tatgagggta ttgcgtaata atgcagccca
    19501 tgcgaaagac tgtcgaattt ctgaatcaac agttttagaa ttatggaatg aaattgagta
    19561 tatatatcct tactttgtaa tcaacggaac gattgatgca tggatggaag atttagaaaa
    19621 actagttaga tattcaaata gtagcataga atctcaaaac caattacaga ataaatttgg
    19681 agatttttct actgaaaata agaccttaat tgttaaaaag attatacaaa aatatttggt
    19741 agattctgaa tgggatgaaa cgtacccaga tatagtgatg aattttttat tatatatttt
    19801 tcaagaaagt aattatatta atcaaattgg taaagactta acggaaaaag aggaattgta
    19861 tctgtctatt ggaacgggta tttatcattt ccaagctgaa gctattgata tttattctca
    19921 atttgaagag tcgctgagtg attatacatt tagatatttt tgtgaagaat tttcggataa
    19981 tttttggaag tttattgatt ctatggattc cgaagttaat aaagagaact tgacagctac
    20041 tagtttagaa attttgaaga aaaattctgc tattttagta aatgcagaat ttaatgagag
    20101 ccgattttta tctgataata gtcttttttt caaatctgtg tt
//
LOCUS       DAUGUF010000033        19370 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUGUF010000033 DAUGUF010000000
VERSION     DAUGUF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19370
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.033"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            52..1101
                     /locus_tag="VIB71_001355"
     CDS             52..1101
                     /locus_tag="VIB71_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEQ8823089.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCEDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVKPGDNVCIVGAGPVGLAALLTVQFFSPANIIMVDLSQNRLEAAKTFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            complement(1183..2349)
                     /locus_tag="VIB71_001356"
     CDS             complement(1183..2349)
                     /locus_tag="VIB71_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEQ8823090.1"
                     /translation="MENQLGQLALEQAKTFGGKLEVQPKVDIKNKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRLVVLKS"
     gene            complement(2381..3712)
                     /locus_tag="VIB71_001357"
     CDS             complement(2381..3712)
                     /locus_tag="VIB71_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEQ8823091.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSENMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKDVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            3873..5414
                     /locus_tag="VIB71_001358"
     CDS             3873..5414
                     /locus_tag="VIB71_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8823092.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            5395..6060
                     /locus_tag="VIB71_001359"
     CDS             5395..6060
                     /locus_tag="VIB71_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ8823093.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(6115..7188)
                     /locus_tag="VIB71_001360"
     CDS             complement(6115..7188)
                     /locus_tag="VIB71_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8823094.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(7181..7957)
                     /locus_tag="VIB71_001361"
     CDS             complement(7181..7957)
                     /locus_tag="VIB71_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823095.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            complement(7954..8748)
                     /locus_tag="VIB71_001362"
     CDS             complement(7954..8748)
                     /locus_tag="VIB71_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823096.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            complement(8732..9886)
                     /locus_tag="VIB71_001363"
     CDS             complement(8732..9886)
                     /locus_tag="VIB71_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823097.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            complement(9932..10819)
                     /gene="murB"
                     /locus_tag="VIB71_001364"
     CDS             complement(9932..10819)
                     /gene="murB"
                     /locus_tag="VIB71_001364"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEQ8823098.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLKAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTPSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVKLEPEVRIIGENL"
     gene            complement(10969..11469)
                     /gene="folK"
                     /locus_tag="VIB71_001365"
     CDS             complement(10969..11469)
                     /gene="folK"
                     /locus_tag="VIB71_001365"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEQ8823099.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            complement(11466..11825)
                     /gene="folB"
                     /locus_tag="VIB71_001366"
     CDS             complement(11466..11825)
                     /gene="folB"
                     /locus_tag="VIB71_001366"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEQ8823100.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            complement(11832..12632)
                     /gene="folP"
                     /locus_tag="VIB71_001367"
     CDS             complement(11832..12632)
                     /gene="folP"
                     /locus_tag="VIB71_001367"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEQ8823101.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCHLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            complement(12641..13225)
                     /gene="folE"
                     /locus_tag="VIB71_001368"
     CDS             complement(12641..13225)
                     /gene="folE"
                     /locus_tag="VIB71_001368"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEQ8823102.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            complement(13260..14537)
                     /locus_tag="VIB71_001369"
     CDS             complement(13260..14537)
                     /locus_tag="VIB71_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ8823103.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYP
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRQYWKKHIEKNVLLTH"
     gene            14869..15831
                     /locus_tag="VIB71_001370"
     CDS             14869..15831
                     /locus_tag="VIB71_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8823104.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEIGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQTSPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            complement(15948..17183)
                     /locus_tag="VIB71_001371"
     CDS             complement(15948..17183)
                     /locus_tag="VIB71_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ8823105.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSEPHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDHRYPGSTLEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCCRKILKKGSLVSERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(17341..18528)
                     /locus_tag="VIB71_001372"
                     /pseudo
     CDS             complement(17341..18528)
                     /locus_tag="VIB71_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943304.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(18531..18751)
                     /locus_tag="VIB71_001373"
                     /pseudo
     CDS             complement(18531..18751)
                     /locus_tag="VIB71_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            18838..18981
                     /locus_tag="VIB71_001374"
     CDS             18838..18981
                     /locus_tag="VIB71_001374"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823106.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            complement(19052..19270)
                     /locus_tag="VIB71_001375"
     CDS             complement(19052..19270)
                     /locus_tag="VIB71_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8823107.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNK"
BASE COUNT         6070 a         4130 c         3334 g         5836 t
ORIGIN      
        1 tgtgtaaaaa tgaattggtt gattacctct caaccttata aggagttaaa tatgaaagca
       61 gcaacttatc tttcaaccgg aaatctacag ctcatagaca aaccaaaacc agtcattata
      121 aagcctacag atgctatcgt ccagttggta aaaaccacta tttgtggaac tgatttgcat
      181 atcttaggtg gggatgttcc cgcatgtaaa gaaggaacaa tccttggtca tgaaggaatt
      241 ggaattgtta aggaggtcgg tgatgcggtt actaacttta aaatcggaga taaagtgatt
      301 atttcttgcg tcacatcatg tcatacctgt tattattgta aacgaggcct ttcgtcacat
      361 tgtgaagatg gcggttggat tcttggccat ttaattaatg gaacacaagc agaatatgtc
      421 catatcccac atgcagatgg tagtctctat catgctcctg atacgattga tgatgaggca
      481 cttgtcatgc tttctgatat tttaccaact tcatatgaaa ttggtgtctt gccatcacat
      541 gtcaagcctg gagataatgt ttgtattgtt ggtgccggtc cagtaggact cgcagcccta
      601 ctaaccgttc aatttttctc tccagccaat attattatgg tcgacttatc tcaaaatcgc
      661 cttgaagcag ctaaaacatt tggagccaca cacacgattt gttcaggaag tagtgaagaa
      721 gtcaaggcta tcattgacga tataaccaat ggacgtggtg tcgatatttc catggagtgt
      781 gttggttatc ccgcgacatt tgatatttgt caaaaaatta tatcagtagg tgggcatatt
      841 gctaacgttg gggttcatgg gaaaccagtt gatttcaacc tggatgaatt atggattaaa
      901 aatatcacct taaacactgg acttgttaat gccaatacaa ctgaaatgct actaaatgtc
      961 ttgaaaactg gaaagattga cgcaacaaga cttattacac atcattttaa actttcagaa
     1021 gttgaaaaag cttatgaaac ctttaaacat gctggtgcaa ataacgcctt gaaagttatt
     1081 attgataatg atattagcta atcacaaaat aagtagaagc tagaaatatg cttctactta
     1141 ttttgtgatt taaagtataa ctttctcttt ttttcatata ttctatgatt taaggactac
     1201 caacctgacg cttttagcga caatctcagc gactccttct ttaaaggcat ctggaataat
     1261 attagtagtg ctcaaagcgt catctgggac aagactggca ataccttttg cggcagcaat
     1321 ttgcatctca acagtaatgg tttttgcccg tgcatctaat gctcccctaa aaatacctgg
     1381 aaaggcaagg acattattaa tctggttagg aaaatcactg cggccagtac ctacaatgta
     1441 agcccccgct tcaagggctt catcagggta aatctctgga atagggttgg ccatggcaaa
     1501 aattactggg cgcgctgcca ttttactaat ccactctgct tttaagactc ctggtgctga
     1561 tacgccaatg aagatatctg ctccttcaag agcatcttct aaggtacctg atttaaactc
     1621 acgattagtg actttcgcta tatccaaatg atgtggcgct aattgagcgg cttcttgttc
     1681 attgataatg ccaaatttat ccactactgt cactttcgta gcacctgctg ctaataattt
     1741 acgggtaatg gataatccag cagatccacc accgttcacc acaatggata cctcatcaag
     1801 ggatttttta agaagtttca aactattgaa gatggctgct aacaccacaa tagctgttcc
     1861 atgctgatcg tcatggaaaa caggaatatg acattcctta atcaagcgct gctcaatttc
     1921 aaaacagcgg ggcgcactaa tatcctccaa attaatacca ccaaaggttg gtgcaagcgc
     1981 cttgacaata ctaataattt cttcagtatc tttggtatct aatacaatcg gaatagcatc
     2041 gacacccgca aatgctttaa aaagggctgc ttttccttcc ataactggca tggctgcttc
     2101 agggccaata tcccccagac caagaaccgc agtaccatca ctgataacgg ctactgtatt
     2161 tttcttggtg gttaagtcat atgctaatgt tttatctttt gcgatggcag atgacacact
     2221 agctacacct ggtgtatagg caatgctcaa atcatgttta tttttaatgt caacttttgg
     2281 ttgaacttcc aatttccctc cgaacgtttt agcttgttca agggcaagtt gacctaattg
     2341 attttccata gggaatacct ctctttttta ttggtttgga ttaactaaaa ataattctta
     2401 aaatagctgt catagtgata acggtaatag ccccacctaa acgggtagcg acttgggcaa
     2461 acggcattag attcatgcgg tctgcggtac tcaaaatagc cacatcacct gttccaccca
     2521 taccactttg acaagctgaa ataatagctg cttccactgg gttcatgtta aggaaacgag
     2581 agacaaaaaa accgacactg acaaccgtta acaccacact aatcaccaca ataaaatatt
     2641 gccagctaag ggtggccaca acatctttta atgggatata aaggagtcca agccctgcca
     2701 ttagtggaaa agtaaagttg ctggaaataa atttataaag ttgtttggca ccattttgtg
     2761 tttcttgggg gataacattc aggtatttca agaaggccgc caagataatc atcaacaccg
     2821 gtcctggaaa acctgttaaa tgctgtaaca agccaccggc aataaaaagt gaacaagctg
     2881 ttaaaactcc tgcccccatt aatttaacat ctaaggctcc agaattgtct tttagggcat
     2941 cagacatatt ttcgctgtga ccaattttaa ccagttgccc ttgaccagaa taacttggat
     3001 gcttctcccc aaaacgattg agcaaagccg tgcacaagat agcaaagaaa ttcccaataa
     3061 tggtggctgg aatcagttga gccactaatt gctcacttcc gactcctgta atggcactgt
     3121 aaccaagaga taagggtaaa ataccttcac caattcctcc agcaaggact ggcgtcacaa
     3181 cataaaagag ggtatgttgc cagtctaatc ctaaaatgac gccaaccaaa gtccctacac
     3241 ccattgcaca aaccattcca agtaacatgg gaataatcat ccgaaaaaga ccttgaatca
     3301 agatttttcg attcatgcct aaaatactac cgcagaccag gcaggcaata taaaaataaa
     3361 gaaaattggc ttgcttcatc aagacattcg tcgcttctaa gacattggga ttgaggagat
     3421 taaaaaaaac caaaatcgaa gggactaaga gtgataaaat agctgggcca ccaaaatgtt
     3481 tgaggcctgg aatggtcgct ccaatggttc ctagtagcca accaagggtt aaaataacag
     3541 caaagccacc cagcatatta acaggcaatt gttggagcca gcctgtgact aaaattaagg
     3601 tagctaaaac cagataaaca ggcaagggaa cggagcctat tctcctattt tgccatgctt
     3661 ttgaatgctc agacaagtct ttttgaggca ttttcttgct tattgtttcc atgaaacaac
     3721 ctcctttagt gataaggcta gtataaaaga gaacatgtca aaagcatagt ttatttaagt
     3781 tgtttaacta ctttaatttt ttcaagttat ttaattaatt taagctagca ggtcatttct
     3841 tatcgtgtta tactcaataa agaggagacc ttatgaaaaa accactacgt ttatgggcca
     3901 gtttatcgtt gattttggta tctatgattg ttgtcacaac ctctctattt tacgggatta
     3961 tgctacatga tacgcaccaa tccatcaaaa atcaggaaac ccatttgcta acgtcaactg
     4021 gaaaaatgtt agcaagtcat caagcgatta aagaattact cctaaacaac caaccaaatg
     4081 ctaaaacaac agcctatacc aactccattg cctccatcta taaccttgat tatgtggtcg
     4141 tgatgaacat gaaagggatt cgactcaccc atcctaaccc gaaaaatatc ggaaaacctt
     4201 ttcaaggagg tgatgaggag gctgttctag caggaaaaaa ggttatctct accgccaagg
     4261 gcactttagg aaagtcactt cgctatctag tacctgtgtt tgacggtgac aaacagattg
     4321 gtgctattgc ggttggcatt aaactaacta ccctaaatga tgtggcttta acgtcaaaac
     4381 gcaattatac cctgtcttta ctcctttgtc ttcttattag tttactggtc accagtttta
     4441 tttcttttcg actcaagcgt caactgcacc agttagaacc aagtgaaatt tatcagctct
     4501 ttgaagagcg taatgccatg ttggatcaaa tcgaagccgc cgtatttgtg gtagataaag
     4561 ctggtatctt acagctctgc aatcaggctg gacaaaaatt aattgctcgg aaatgccagt
     4621 tgggaaaacc tactggcaac agtttcaatc acctctttcc tgattttcca aaacttagtt
     4681 tgcaagaggg gcatgaacaa ctctttcggt atggtgagga agactacttg ttagccattt
     4741 cacccatctg tgtcaaaaac gatcaccgag gccacattat tttcatgcga gaagcagtta
     4801 aggctattga taccttggat cagctagcct ataccaccgc ctatgcttct gctctacaag
     4861 cccaaactca taaattcatg aatcaattgc atgttattta tggcttggtg gatattgctt
     4921 attatgacca attgaaaatt tatttagaca gtattttgga gcccgaaaat gaaattctca
     4981 ctagcttatc tgtccttgtt aaggagcctc ttctagctag ttttctcatt ggagagcaag
     5041 agaaatacca agaattaaat gtccatctca agattgatgt tttaagcgag attcctcatt
     5101 ctgccaccaa gaatcaactt aataatggtt tgatgattta ccgctttatc catactaatc
     5161 ttctaaccac actgagaccc aaatcactcg ttttgagtat tcaacatgat cagaatcatt
     5221 taatcagcca ttacaccttg acagacaatt ggattgattt ggagcgggta cagcctattt
     5281 ttgacttacc ttattttcaa cagctcttga ccgatacaaa ttcccaattc catcaacatc
     5341 aaaccgtaac cgagttacag ttctcagtga caacacctta tgtaggaggg caacatgaac
     5401 gttttaatca ttgaagatga tcctatggtg gattttatcc atcgcaatta cctcgaaaaa
     5461 ctaaatcttt ttgatcgcat tatatccagc gactctatga aagctgttca aagcatactt
     5521 actgattacg caattgacct cattttactg gatattcata ttacagatgg caatgggatt
     5581 caatttttgg agaaatggcg tgctcagcat attccttgcg aagtcattat tatttcagcc
     5641 gcaaatgatg ggaatattat ccgagatggt tttcatttag gaattatcga ctacctcatc
     5701 aagcccttta cctttgaacg ctttcaagaa agcatccaac agtttgttac acatcgagaa
     5761 catttggcca atcagcaact agagcaggcc caaattgacc aactgaaatg tttgactagc
     5821 aaaaaagaca ctaaaaacaa acaattgtta gaaaaaggct tatctgaatc cactttccag
     5881 tggattatgg aaaatatcaa agcctttgat caacctttta ctatccaaga attagcttcc
     5941 gcttgtcact tatcccatgt ctctgtccgt aaatacattg cttatttaga agaaaataag
     6001 caactgaaca gccaacaaat ttttaccaag gttggccgtc cctatcgcgt atactggtga
     6061 cgtcatctgt cgatacatta aaaaggctgg agaaatacca gcctttttga gtgcttattt
     6121 gcgatacatt ttaaattgga ggtataaatc attataaatc cccaaccatc ttgaccctaa
     6181 attgtcataa acttccaatt ttttgataat gtcatctgtt ggataaaaag caggatcatt
     6241 ttttatctca tctggaagta aggccttggc ttttttattt ggtgtcgcat aaccaatata
     6301 tgcagcattt tgcgcagcat tttcaggacg attgataaag ttcaaaaaag cataagcttc
     6361 tttttcgtgt ttcatggttt ttggtagtac caaattatca aaccaaaggt tagacccttc
     6421 tgaaggcacg atgtagtgaa ggtgttcgtt actatctaac atctcactgg cttcaccaga
     6481 aaaggtaatt ccaatagcag cgtcaccttg aatcatgtag cctttcatct catctgctac
     6541 aatggcttta acattcggcg tcaactgctg cagttttctc tcggctgcct gcaactgctc
     6601 cagattttta gaattcacac tataaccaaa agttgttaaa ccaaccccta gcatttcacg
     6661 cgctccatca atcagcataa tactattttt atattctgga cgccacagat cttcccagtg
     6721 cataggcgcc ttatcaacta attgatcatt ataaacaatc ccaacggttc cccagaaata
     6781 aggcaaagaa tagtcgtttt gtgggtcaaa gcttttccct aaaaattctt tcccgatatt
     6841 atccatgcca actaattttg acttatcaag cttattgagt aggttttctt tgatcatttt
     6901 atcaatggtg taatcactag gaacagcaat gtcgtaagtg gttccgccct gcttgatttt
     6961 agtgtacatg gcttcattgg aatcgaaagt ttcatactgc acttcaatgc ccgtttcttt
     7021 ggtgaatttt ttgagcaaag ctggatcaat gtaatctccc cagttataaa taactaattt
     7081 atccgattga ctaccagaac ccgatttttt ctgcaagatg aaagaaagac ttgttaaaat
     7141 aacaataaca cccaaaactc ctgctagaaa ggaataaagt ttacgcatgt ttttcctcct
     7201 tgtcctgtga catataataa taaccgatca ctaagaggat ggagaaaaag aaaacgatgg
     7261 ttgacaaagc attgatatcc aaggaaattc cctgacgagc ccgcgaataa atctcaacag
     7321 ataaagtagt aaaaccattt ccagtcaaaa agaaagtcac tgcaaaatca tctaaggaat
     7381 aggtaaaggc cataaaataa cctgcaataa tccctggtgt taagtatggc agcatgactt
     7441 ctttgagcat ttggaaataa ttagctccca aatcataagc ggcgttgacc atgtcttgat
     7501 tcatctcttt caagcgcggc aataccatca aaaccacaat aggaatcgaa aaagcaatat
     7561 gacttaataa aactgaagac atgcccagct gaaacttcaa tgatgtaaaa agaattaaaa
     7621 aggaagcccc aatcatgaca tctggtgata ccatcaagac attattggct gatagcatgg
     7681 cattttggta cttacctcta acatggtgga taaagatagc tccaaaggtc ccaataatcg
     7741 ttgctagtag agcgctacta aaagcaagaa caaaggtttg cagtaagatt gtcatgagac
     7801 gactatcctc aaacatggtt tggtaatgct caagggtaaa tcctgtaaaa ccattcatat
     7861 ccccaccttt gttgaaagaa tagaaaatca aataaaaaat aggaatgtag agtaaaacaa
     7921 agacactcgc taaataaaga ttggcaaatt ttttcattta cttttctcct ttgtgagcca
     7981 cataatagca accatggtca aaatcaagac gacaccaatg gttgatccca ttccccagtt
     8041 ttgggtggtc aaaaaatgtt gttcaatggc tgtaccaagt gtaatcacgc ggtttccacc
     8101 aatcaaacgg gttaacataa agagactcaa acttgggata aagacagact gaacacctgc
     8161 cctaacccca tttaaagaaa ggggaaaaat aacttttgag aaggcctgaa attcactagc
     8221 tcctagatcg cgactggcat tgatgacatt atggtcaata tcatccaaag cattaaaaat
     8281 cggtaacatc ataaaaggaa gctcaatgta agaggctaca aaaatgaagg agaaatccgt
     8341 gaaaaggatt tgctgcgggc caatccccat aaaggttaaa aagctgttaa tccctccttg
     8401 ttgaccaaag attcccataa aggcataggc ttttagcaat aagtttaccc aagttggcaa
     8461 aataatgagc ataagccaca actgcttgtg ctttaggcgc gttaaaaaga gagccgtagg
     8521 atatgaaatt aagagcgtga cgagtgtgat aataccagcg tataaaatag aattcacact
     8581 cattctcaaa taggtccaag agctaaaaaa ggtttcataa ttggctaagg tcacgcgccc
     8641 ttctatgtca aaaaaggact tgtaaaacaa gagagtgact ggtgccacaa caaaaaagag
     8701 aatccataag aagtaaggaa tcgaaaaaag actagaggtt ttcttcatta cgctcctcct
     8761 caatggcatt aatcaatcca tcttcaggct catccatttc cacatattct tcaatacggg
     8821 catcaaattc ctcttcagtc tcattaagac gcatgatatg aagatcttca ggggtaaagt
     8881 ctaatccgat aacttctccc tcgatagctt tgcgggtaga atgaatcatc cattcattac
     8941 ccaattcatc ataggcaata atttcgtagt gaaccccgcg gaataattgg gtatcaacct
     9001 taacttgtaa tttcccttct tctggcaaag taatttgaag atcttcagga cgaataacca
     9061 cttcaacagg ctcattaggg cgcattccac cgtccacaga ttcaaattct ttcccgttaa
     9121 aggagacaag atagtcttca atcatggtac cgttaataat attagattct ccaataaaat
     9181 tagcaacaaa atgattaatt ggctcatcgt aaatatccac tggtgttccc gactgaacaa
     9241 tttcaccttc attcatgaca aaaatccaat cactcatggc caaggcttct tcttgatcgt
     9301 gagtaacaaa aacaaaggta atgcctagac gttgttgcaa ttcacgtaat tcatattgca
     9361 tctctgttct taatttcaaa tcaagggctg agagtggttc gtcaagtaag accacacgcg
     9421 gttgattgat aatcgcacgc gcaatggcaa cacgttgacg ttgaccacca gataacttct
     9481 ggatagaacg attttcatac ccttctaatt gaaccatttt caaggtttct ttcacgcgct
     9541 tagcaatctc tttcttgtcc actttcttca gcttcaaagc aaaggcaaca ttctcaaaaa
     9601 cagtcatatg agggaagagg gcataatttt ggaaaacggt atgaatgtca cgtttattaa
     9661 tcggcaaatc attaatacgt tccccatcta aataaatgtc tccgctgctg gcatctagta
     9721 ggcccgccat aatatttaaa atagttgatt ttccagagcc agaagctcca agcagggtgt
     9781 aaaattttcc ttcttcaagg tcaaagttaa tgttctttag aacctgtgtt ccactgtcct
     9841 caaatgtttt tgaaacattg ttaaatgtga taattggctt agtcaattgt cataaatcct
     9901 ccacggtact ttctttaatt atcaataatg gttacaggtt ttccccaata atccgaactt
     9961 ctggttcaag cttgacacca gaatggtttt caactgtctc aatgacataa gcaatcaaat
    10021 cttcataatc tttagctgtg ccatctgcca cattaatcat aaaaccagcg tgtttttcgg
    10081 aaacttccac accaccaatc cgatgccctt taagatttgc ttccatgatt aattgacctg
    10141 caaagtgtcc tggcgggcgc ttaaacacag atccacaaga tggaaattct aaaggttgtt
    10201 ttagttggcg aaggtgattt aacctattca tttcttggct gatcgtatca taattacccg
    10261 gcttaagagc aaacttagca gaaatgacaa tgtcacctgt ttcttgaatg gcagagtgac
    10321 ggtaaccaaa agccatatcc ctagctgaaa tggttttgat ctctccactt ggggtaagca
    10381 ccttagcgga taagaaaata tgtgatattt ccccaccata agcacccgca ttcataaaaa
    10441 cagcaccccc aatgcttcca ggaatgccac atgcaaattc aaaccctgtt aaactatgga
    10501 atttggcaat cttcgttgtt tcaatcagat tggcaccagc ttcggctttt aaggtataac
    10561 catttaagtg cactgcattt agcttatcaa acatgatgac aaagccacga ataccaccat
    10621 ctcgcacaat gagattgctg gcatttccca aaacaagcca aggcatattt tctttgttgg
    10681 cataagcaac gatgcgtgat agctcgtagt gatttctagg aaaagccaag aaatctgctg
    10741 ggccacctac cttagtgtaa gtgtaatgtt ttaggggttc attctctcga atatcaatcc
    10801 catgaagttc agttatcata gttatcttct ttcttttatc acttcttata cgcgtaaaaa
    10861 aatcggcata aagccgatac tattatatca aattttagaa aaaataacga tgaatttggc
    10921 aaaactttat ggattggctt atagcaggca ttactccgaa aacagagtct agaactctgt
    10981 ctgttgagct gaaaagagcg tgatatctga ttgatctaaa gctgcaagat aatcccttaa
    11041 aaacttatga ttaggaggca attttaaatc tggctgcaat tccaataagg ggattaaaac
    11101 aaaagcacgc tcagtcatat aagggtgtgg cactttcaat tcctttgtgt cataaacctc
    11161 ttctccaaat agcaagatat caatgtcaat agttcttgat ccccattttt catgcctcac
    11221 acgaccaaga gattgctcaa tagcttgtgt ttcttttaag aaatcagccg cggttaattg
    11281 tgtatctaat tgacaggcca tattgagaaa atcagcctgg cctgtcttgc cccaagcagt
    11341 cgtttcataa atggatgatt gagcaagcaa ccgtgtttga ggtaagtcag ctaaagcctc
    11401 aagagctttt tgcaagtaag ctgctcggtc ccccatattg gtgcctaaac ttaaataaac
    11461 aatggtcatc tctgtctctc caattcaata ccaactgcct tatagtggcc tgcaatcggt
    11521 gggttttcct ttttaatggc cactttgatg gcttcaatag gtggaaattc gttaaaaagc
    11581 tgttcacaaa tcgcacctgc taaacgttca atcaaaataa acttttcccc ttccactaac
    11641 tgacggacac tatcaaacac catcccgtaa tggaccgtat ctgttaattg gtctgacaaa
    11701 gaagctgctt gcaaatcgac tgacaattct aaatcaacca gaaaaatttg cccaagggtc
    11761 tgttcttctt taaaggctcc atggtagcca taaaaacggc aaccttctaa tacgatttta
    11821 tccataagtc ctcacatcaa ctggctcaac acagccacaa tgtcttgatt agccttgaca
    11881 tcgtgtacgc gtacaatctg acagcctttt ccaagggcat aagcagacaa ggctgctgtc
    11941 gctccgtctc gctctttagc tttggtgttg ccgcctaaca aggcatctac gacacgcttt
    12001 ctcgaaatac caaacaagac aggatagccc aaatgacaga cgcggtccaa tccttttaat
    12061 aactccgtat tctgttgaac agatttggca aatccaaatc ctggatcaac ccaaatattg
    12121 ttttttggca cgccagcatc aagagctgct tgtgctctat tgcctagaaa atcacaaacg
    12181 tcttgtgtta cctcttgata aacttcttcg tcttggttat gcatcaagat gataggcgca
    12241 tcgtactcgg ctgctaaggc aaacatttga ccgtcgtaca aacctgccca aacatcattg
    12301 agaatatcgg cacccgcctc taaagctgct ctagctgttt cggttttata ggtatcaatg
    12361 ctgattagaa tatcatagtt ttctttgatg gccttgatca caggaaccac ccggtcaatt
    12421 tcatcggtag cgcttacaaa ttggcaacct ggacgtgttg attctccacc aacgtcgatg
    12481 attttagccc catcagcaat catttgctca acgtgatcta atgctttttg cacagtagtg
    12541 taagaccccc catctgaaaa agaatctgga gtcacattta aaatccccat gatagccgca
    12601 ttgccctcaa tcacaaactt tccaattttc ataagttctc ctaatctttt gtcattagag
    12661 aaataacttc ttgcctctca gcacgacttt ccttatataa gcctctggca gtggtggtaa
    12721 tggttttact acctggcttt ttgatgcctc gcatggtcat gcacatgtgc tctgcttcta
    12781 ccataactaa agtcccttta ggattgaggg cttcaactaa agcatccgct atttgagagg
    12841 tcaaacgctc ttggagttga ggtcgtttac tagctacttc aactgctcgc gctaatttac
    12901 tcaaacctgt tactcgacca tcacttggca agtaagcgat atgagccttg ccataaaaag
    12961 gaactaagtg gtgttcacat atagaataaa aactaatgtc tttgacaatc accacatcct
    13021 catgttgttc tttaaagaca gccgtaaact cctctttagg atcttttccc agtcccaaaa
    13081 acatctccgc atacatttta gcaacccgtt taggcgtgtc aagaagacct tcccgatttg
    13141 gattttcacc aatagcctct aaaaactgat aaatggctgc ttctgctttt tccttattaa
    13201 tagacattag tctttccctt ttcattagtt ttttcctttt ccttttcatt ttctcttttt
    13261 taatgggtta aaagaacgtt tttttcaata tgttttttcc aatactgtct aatttctgaa
    13321 ataaaatata gcgaccctgt aatcacgaaa aagtcatctg ctttggcatg cttacgcagg
    13381 gccaagaaat ctttgaaatc agcaacccta ccaaaacgtt ctgggtattt ttccaatgga
    13441 taggcgttag ggtaatgaaa gccagtaacc tgcaagtcac ctatttgctc aagagcaacc
    13501 aacatatccg caataggctt ggtgtcgatc gcaccaaaca aaatatgaag ctttttatca
    13561 ttgtagttat tttttaagac ggctaccaaa gcagcaacgc tttcattgtt atgagcccca
    13621 tcaatcatta gatttggtgc taataattcg gtacggccta gccacaaact atttgccaga
    13681 ccttccctta tatgatctga agttagccta ggatagcggt ctttcaaggt taagcaagtc
    13741 ataatagcta aagctgcatt agacacttgg tggtgtcctg gcatagcgat gtgaatatct
    13801 gaaataactc ctaaaggact agtaaaacga tagccagatg cgttctcagc catttgaaac
    13861 tgctcttgcc attcccagat tgaagcacca acctgctcag cttttgttaa aaaaacctct
    13921 cgagctgacg ggttttcaac ggcaaaaaca agggtctcgc ccccttctaa aacaccagct
    13981 ttttgggcgg caatatcagc gtaagtctct cccaaaatag cttggtgatc taaaccaatt
    14041 gagggacata ccacaaccat tgcttgaaaa acattggtcg aatcataaag accgccaagg
    14101 cctgcttcaa taatagcaat atctacagga tgcatgtctc caaaatagag gaacatgatc
    14161 aaagtaatca cttcaaattc agttacctct ccaaaatcag tctcttgaac tagacgctct
    14221 gtcaaaggac gaatacgatt agcagcaata accaaatctt tttctgaaat cattcgacca
    14281 tttatgctaa tacgttcttt gaaatccata atataaggag aggtaaaggt ccccacttca
    14341 taaccagctg tcgtaaaaat gtgttgtaaa tgattgaccg tggaaccttt tccgttagtt
    14401 ccaacgatat gcactccctt gacatttttt tggggatttc ctaactgtcc aagaacccaa
    14461 agcatacgtt ttaagcctgg cttgatgccg aaaactaagt gatcatgaat ccattctaga
    14521 gtctcttcat aagtcatttc acacctcaca tctatcttta gtataccata tataaaaaaa
    14581 agtgacagca gataacctag agtagtaccc ttttttttat tatcctcacc aaacactcaa
    14641 ataagttcta aagtacacta cacttttatc ttcattgctt tttttacgtg ataagaatac
    14701 cagccccaca tagtctttgc tacctcctaa agtgttatct gtgacaataa tttttttact
    14761 ccttaataca cgttcttcca aaaaacaaga aaaaaggctg acttcaagcc ttcttttctc
    14821 taaaaaatgt tacaatagag gtacttatat caaaaaaagg agcaagtaat gaacaataga
    14881 cataaacggc gccaaaaaag aaaagccttc actctcatta accttatact attatttgcc
    14941 tgcattcttg gtttgaccct cattttctat ttataccaag ggtctaacaa attcggcttg
    15001 tcagatgtct ctcaatttgt acctaaaata agtctttttc atcacaaaaa gacggcaaaa
    15061 aaagaaacga caaaacttaa gaagactcat ttcgattcct caaaatctca aaaaaaggcc
    15121 cattctaaat taacttggac caagcaagaa acacctgtca agatccccat tttaatgtat
    15181 catgctattc atgtaatgtc ccctgaagag acggccaatg ctaatttgat tgtcaaccca
    15241 gatctctttg atcaacaact tcaaaaaatg aaagacgagg gctactattt tttgagtcct
    15301 gaagaggtct accgcgctct ttcaaataat gaattgcctg ctaaaaaagt tgtatggcta
    15361 acatttgatg acagtatgat tgatttctac aacgttgctt acccaatctt aaaaaaatat
    15421 gatgctaaag ccaccaataa tgttattaca ggactaaccg aaataggaag cgctgccaat
    15481 ctgactctta agcagatgaa agaaatgaaa caattcggta tgtctttcca agatcataca
    15541 gtgaatcatc ctgatttaga gcagactagt cctgatgttc aaacaactga aatgaaagat
    15601 tcaaaggact atcttgataa gcaattaaac caaaacacta ttgccattgc ttatccatct
    15661 ggtagatata atgacactac tttacaaatt gcagctagac ttaactataa attaggtgtt
    15721 accactaacg aaggaatagc tagcgcggct aatggacttc tttctcttaa ccggattcgt
    15781 atcctcccaa acatgagtcc ggaaaatctt ttacaaacaa tggaaccata acatcaattt
    15841 ttttatcatt ccaaatcata ctcactgtaa actaaaaaga cagttatgaa aaaattcttt
    15901 cataactgtc tttttttgat tgttttaaaa ttattttatt cttatcttta acgtcttttt
    15961 tcaagaaaat ctcgccacca cagctgtaag tcagaggctt ttttaagaga ttggctagct
    16021 ttaagaggaa tacgcttagg ttcctttaaa tacctcactg actgatctgt tattcttgga
    16081 gacgtcaaat aagcaaccac ttcaccttta gtaatcggtg ctagtaaaga agtctctgat
    16141 atcataaatt gtttaggttt gggaacttgt tcaccctgtt gcaaaatgat ggttacatct
    16201 tcggcaacag ataccggtag ttcttttact tggccatctt gaatagggag cgaccgctcc
    16261 gagacaagac ttcctttttt aagaatctta cgacaacaat aagttctagc cacatagtcc
    16321 aacaaacgat ttgcttgctc aaaccgcgtg ttttggtttt tatcagatcc atcggcattt
    16381 agaataacgg taatcactcg cataccattt tcaatagaag ttaccacaag acaatgacct
    16441 gccaagtctg ttgtcccagt ctttaaacca tccactcctg ctctaccctt agccatacct
    16501 ggtaagagtt gattaaaact tttaatagaa ttgccagcaa aattaacttc tgtttgtttg
    16561 gtgatctcta aaatctcagg aaaatcttct aacaaatgca tcgtcacaac tgcaacatct
    16621 tgagcactca aggtattttc ttcttccaac gtagaaccag gataacgatg gtcctttaac
    16681 acctcatttg gcagacctga ggcgttgagg attttaccag aagtaatccc ccaatgagat
    16741 agctgttctc tcatttgatt tacaaaatga ggctctgagc ccgccacttt ttcggccaac
    16801 gcaatagcag cgctatttga gcttgctacc aaagtagctg tcaacaggtc ttgaactgaa
    16861 taagtttttt tgtcaaaagg tacattactt aaagacctat cttttgttaa ctcgaaggca
    16921 taatctgaga gattaacttg atctgataat tgcagctggc ctgatttaac cttatctaaa
    16981 accagataag ccgtcaccaa tttggtcaaa gaggcaatag catctggcgt cttagcgtct
    17041 ttctcataca gaactctccc agagtctgcc tctacgacaa tcgcatgttc tgctcccact
    17101 tgaaaatcag ctgcgagaac tgttttacca aaccctgaac aagttaatac cataaaaaaa
    17161 aggataaccc acctttttat cattatatct ttcatagtta ctattatagc aaaaattctc
    17221 agaaatttgg aaggaagtat agtggcacac acctttagta gcttaaacaa gctcataaag
    17281 caagtaccct gtaacaataa cacatcctgt tatatgggcg atataataag cttcgttata
    17341 tcaattagtt gtttggcagg aattttggta taaaatggaa tctaatcctg aacttattac
    17401 attttgggtt atttcttcag atactgtttt atctaatgcg ttaaatcagt gactatatgt
    17461 attcaaagtt gtagacttat cagcatgtcc catacacttt gcaacgtaca gaatgtcttt
    17521 tttcaaaaca ttaataagat aggaagcatg actatgtcgc aagccttttc ccgttatcac
    17581 tggtactcct acttcttgag ctttgtgctt aataactcga caaatcgttg atttacaaaa
    17641 tggttcacca aaccgtgaaa taatgaaatc tgcgtcagta ttgactactt gatttcttct
    17701 ccaattttcc aatactacta ttgtcacatc atctaactca ataagacgtt ctcctgctgg
    17761 cgtttttgtt tggtctttac gataccaatt tccattttca tccttttcca aggttgtatg
    17821 aactttcaag aatttttgtt cgaaatcgat attttcccat cataatgata aaccttcact
    17881 tacacgaaca cctgtcatat aatatagcca aatagttgta aatctttgta gctcttcata
    17941 atcttgcaaa tcaaacgatt ttataaaatt ctgaaactca atataagtcc aaaatggagt
    18001 gtcgggatgt ttccctttag gattatccaa agccttacat ggcacttttg aaatatagcc
    18061 taacctttca gcatacccca tgcaagcttt gaatcgcgac cataaattct ttgcataatt
    18121 ttcaataata tgtaaactaa aagattcaca atctcaagct gttattccct ttaaatgttt
    18181 agaaccaaaa tactgaataa ataacttatg atgtggtaag gctatttcat aagttacagc
    18241 ctgaaccttt tgcttatatg ctcttaggta aatagtattc atatagtttt caaacgatat
    18301 attgtcattt tcaatactaa gattattact gaactcatac ctaatccgaa ccagttcatc
    18361 atacgcttct ttcattgtac caaatggctt tccatactaa ttctttctgg ctttcttttg
    18421 aactcgttta cctgttactg gatctacacc aagatcagct tgataaaata tcttcccatt
    18481 cttatcacaa taaacacctt tgtacttttt ttgatttttt atagtcatct ttaattctca
    18541 ctttctaaac tttcttcaga gagtagaata cctattaact cttctacaat atctttagga
    18601 gcaataccaa gtcttctatt gtcaaagggc gatttactta attgtaccgc attttgttca
    18661 agttcgcgag cttcttcaac ttttttatag ctattctttt tgcttctcta ataatatttc
    18721 ttgcagtatg ttcgagaaaa ccaatattca tcaagctttt tatatgttac tattttcaca
    18781 cctccactcc tttcaaaaaa attacaacct ccgtgggtat gactggttaa atcactcatg
    18841 ggaatctcac ccactggcct tttacgctgg cagcctgaac gttcagaagt atcattgtcc
    18901 ctatttgtgg tcatggcaga tagagaacca ctctatttta tagctaataa ttatcgctcc
    18961 tatcacggcg tatctcacta aattgctcga caaacaagaa agtcccgcct cggtttattc
    19021 agttgtcaat gaacaaatca aggcgagact tttatttatt atgaaaacga tacggataat
    19081 ctgtttgccc taataaataa tcaatactga cgttatagag tttagaaaac tgcacaagaa
    19141 catctgccat taaggcaacc tctcctctct caatttttgc ataatttgca tgagagaagg
    19201 aaagtaaatt tgcaacaaac ttttgagtga aatcgttatc ttctctcaaa ttcctaatac
    19261 gcggatacat ctaacattct ccgaatatca gtataaagga gatttgatta aaaaatgttt
    19321 aattgtccta tttggacaag tctattaaat ataagctagt aaaccattga
//
LOCUS       DAUGUF010000034        18561 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUGUF010000034 DAUGUF010000000
VERSION     DAUGUF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18561
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.034"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            80..1912
                     /gene="lepA"
                     /locus_tag="VIB71_001376"
     CDS             80..1912
                     /gene="lepA"
                     /locus_tag="VIB71_001376"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEQ8823108.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK"
     gene            2068..3069
                     /locus_tag="VIB71_001377"
                     /pseudo
     CDS             2068..3069
                     /locus_tag="VIB71_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_164232585.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            3255..3692
                     /gene="msrB"
                     /locus_tag="VIB71_001378"
     CDS             3255..3692
                     /gene="msrB"
                     /locus_tag="VIB71_001378"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ8823109.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            3822..4841
                     /locus_tag="VIB71_001379"
     CDS             3822..4841
                     /locus_tag="VIB71_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEQ8823110.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRIDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            5048..5473
                     /locus_tag="VIB71_001380"
     CDS             5048..5473
                     /locus_tag="VIB71_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ8823111.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            5492..5983
                     /locus_tag="VIB71_001381"
     CDS             5492..5983
                     /locus_tag="VIB71_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ8823112.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            6000..6809
                     /locus_tag="VIB71_001382"
     CDS             6000..6809
                     /locus_tag="VIB71_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ8823113.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            6806..7633
                     /locus_tag="VIB71_001383"
     CDS             6806..7633
                     /locus_tag="VIB71_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ8823114.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            7769..9418
                     /locus_tag="VIB71_001384"
     CDS             7769..9418
                     /locus_tag="VIB71_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8823115.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPNQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPAKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            9422..10210
                     /locus_tag="VIB71_001385"
     CDS             9422..10210
                     /locus_tag="VIB71_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8823116.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            10204..11250
                     /locus_tag="VIB71_001386"
     CDS             10204..11250
                     /locus_tag="VIB71_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ8823117.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNVAMCIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            11365..12762
                     /locus_tag="VIB71_001387"
     CDS             11365..12762
                     /locus_tag="VIB71_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEQ8823118.1"
                     /translation="MTYQTIYPYTNEVLHTFDNMTDQGVADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIIFDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            12864..14660
                     /gene="uvrC"
                     /locus_tag="VIB71_001388"
     CDS             12864..14660
                     /gene="uvrC"
                     /locus_tag="VIB71_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEQ8823119.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            14844..15446
                     /locus_tag="VIB71_001389"
     CDS             14844..15446
                     /locus_tag="VIB71_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEQ8823120.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            15571..16980
                     /gene="pepV"
                     /locus_tag="VIB71_001390"
     CDS             15571..16980
                     /gene="pepV"
                     /locus_tag="VIB71_001390"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEQ8823121.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDTLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNNGAFVLHRFQGGLREN
                     MVPESATAVITSPHDLDVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFTFEGAAKDYLYVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGVIKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(17048..18424)
                     /gene="mnmE"
                     /locus_tag="VIB71_001391"
     CDS             complement(17048..18424)
                     /gene="mnmE"
                     /locus_tag="VIB71_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEQ8823122.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPADLIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
BASE COUNT         5671 a         3419 c         3938 g         5533 t
ORIGIN      
        1 taatccgtaa gaaaagatag gcaaaggcct accttttttg ttataataga aggaaagact
       61 aaatgtatag gaaaatagaa tgaacagtca agatttaaaa aaacgtcagg agaagattcg
      121 taatttctcc attattgcac atattgacca tggcaaatct actctcgctg accgcatttt
      181 ggaaaagaca gagacggttt cgtctcgtga aatgcaggct cagttattgg actccatgga
      241 tttggagcgt gagcgtggga ttaccatcaa gttaaacgcc attgagctta attacacggc
      301 taaagatggg gaaacctaca ttttccacct tattgatacc ccagggcatg tggactttac
      361 ttatgaagta tcgcgttcgt tggcagcctg tgagggagcg attctagttg tggatgcagc
      421 gcagggtatt gaagcgcaga cccttgctaa tgtttaccta gcccttgata atgatttgga
      481 aattttaccg gttatcaata aaattgattt gcctgctgct gaccctgaga gagtccgcca
      541 tgaagtagaa gatgtcattg gacttgatgc ttctgaggct gttctggcgt cagccaaggc
      601 tggtatcggg atcgaagaga ttcttgagca aattgttgag aaggttcctg ctcctacggg
      661 tgatgtggat gcgcctttac aggccttgat ttttgactct gtttacgatg cttatcgagg
      721 cgttatcctg caggttcgga ttgtgaacgg tattgtcaag cctggcgata aaatccagat
      781 gatgtcgaat ggaaaaacct ttgatgtcac agaagttggg attttcactc ctaaggcagt
      841 tggacgagat ttccttgcaa cgggagatgt tggttatgtt gcggcttcta tcaaaacggt
      901 agcagatacc cgtgtggggg atacggtgac tttagctaat aaccctgcta aagaagcctt
      961 gcatggctac aagcagatga acccgatggt ctttgcaggg atttatccga ttgaatcaaa
     1021 taaatacaat gacttgcgtg aagcgcttga aaaattacag cttaacgatg ccagtttaca
     1081 gtttgaaccc gaaacgtcac aagcgcttgg ctttggtttt cgatgcggct ttttaggctt
     1141 gcttcacatg gatgtgattc aagaacgttt ggagcgtgag tttaacattg atttgatcat
     1201 gacagcacca tctgtagtct accatgttca cacaacagat gaggacatga ttgaagtgtc
     1261 taacccttca gaatttccag acccaacccg ggtggctttt attgaagagc cttatgttaa
     1321 agcgcaaatc atggtgccac aagagttcgt aggggctgtt atggaattat cgcagcgcaa
     1381 gcgtggtgat tttgtgacca tggattacat tgatgataac cgtgtcaatg tgatttacca
     1441 aatcccgctg gctgaaattg tctttgattt ctttgataaa ttgaaatcct caacgcgagg
     1501 ctatgcgagt tttgattatg atatgtcaga ataccgcagg tcacaattgg tgaaaatgga
     1561 cattcttttg aacggcgata aggtcgatgc gcttagcttc attgttcata aagaatttgc
     1621 ttatgaacgc gggaaaatta ttgttgagaa attgaaaaaa atcattccac gtcaacaatt
     1681 tgaagtgccg atccaagccg ctattggtca aaaaattgtt gcgcgttcag atatcaaggc
     1741 tcttcgtaaa aacgttttag cgaagtgtta tggtggtgac gtgtctcgta aacgtaaatt
     1801 gctcgaaaaa caaaaggctg gtaaaaaacg gatgaaggct attggttctg tcgaagtccc
     1861 tcaagaagcc ttcttgagtg ttctttcaat ggatgacgat gccaagaaat aaccaagcct
     1921 aatcgcttag tcttcagagg agaactcttg tgggcctaca tgaccaaaaa attgattatc
     1981 tcataaaaaa agaactttac aatctctttc acataacact ataatggtat tatagtgtta
     2041 tctcattatt aggtgagcct gcatttaatc ttattaaaga gaaagaggaa acaaaaactg
     2101 tgaacaaaac aaaacaaaac aaaacatagc cttctttgtc gctatggctt aacgtcagcg
     2161 gctgctcttt tgctggcctt tggaggtgca agtgcggtta aggcggatca acagccaact
     2221 attgaagaga cacagagtca attacaggac ttacgcgaag ctttccctaa actagaagat
     2281 agttatcaag agtgggatat ctttaggcaa aacaaaattt ataagcattt agatgagttt
     2341 gagcataagc taaatagcta tttgaaagta ttagatggaa gtttatctca gttaaagggt
     2401 gaaaaaggtg aacgtggtcc agtaggtccc gctggtccac aaggccttca aggtaccaaa
     2461 ggtgaccgcg gtgaaactgg tgaacaaggt caacgaggcg aaaccggtcc cgctggccca
     2521 caaggtcccg caggtccagt aggtccagct ggcaaggacg gccaagatgg taaagatggt
     2581 cttccaggca aggacggcca aaacggtaaa gatggtcttc caggcaagga cggccaaaac
     2641 ggtaaagatg gtctcccagg taaagacggt aaggacggcc aagatggcaa agatggtctt
     2701 ccaggtaaag acggtaaaga tggcctccca ggtaaagacg gtaaggacgg tcaaccaggt
     2761 aaaccggctc ctaaaacacc agaggtccct caaaaaccag ataccgcacc acatacacca
     2821 aaaacccctc agatccctgg ccaatcaaaa gacgtgacac ctgcccctca atccccttct
     2881 aatagaggtc taaacaaacc acaaacacaa agtggtaatc agctcgcaaa aacaccagca
     2941 gctcacgaca cacacagaca attgccagca acaggcgaaa caaccaatcc attctttaca
     3001 gcagctgctg tagctatcat gacgacagct ggagttgtag ctgttgcaaa acgtcaagaa
     3061 aacaactaat cctctttttg ctacctaact gatggaaagt aaaactcaga gagaacctca
     3121 aggttctctc ttttttgaat caagatagta gctctaggta taacgtcttg tctgaggtgc
     3181 tgtgaacaaa tcagttactg ctcacctctt tttttggtaa aatgtaagca ctaaaacatc
     3241 aaaaggagtt ttccatggaa acatcagatg agttaaaaca acggattggt gatctttctt
     3301 acgaggtcac ccagcatgca gcaacagaat ctccctttac aggggaatat gatgattttt
     3361 ttgagaaggg tatttatgtc gatatcgtca gtggtgaggt cttgttttca tcactggata
     3421 aatttaattc tggctgtggt tggcctgcct tttcaaaacc tattgaaaat cgtatggtca
     3481 caaaccacga tgactcttct tatgggatga gacgagttga ggttaaaagc cgtgaagcag
     3541 gatcgcattt ggggcatgtc tttagtgacg gccccaaaga agctggaggc ttgcgttact
     3601 gtatcaattc agcagctctt aaattcattc cttatgacca gatggaaaaa gaaggctatg
     3661 cccaatggct cacattgttt gatgagacat aacagggtct caaaatgact aaaaaagaag
     3721 cgtcagtgat tcccataagc actggattgg tgaggcgcac gggtcaattt tacaagcctt
     3781 tgtaaaaggt ctataatagg gaatgaaaaa aggaggttag tatgtcaact cacttaagaa
     3841 aacttccagg cctgttactt tgcttattgt tagctcttcc agcctggtgt ttagggcgct
     3901 tgtttcctat tattggagca cctgtttttg ctattctttt aggaatgttg ttagccttgt
     3961 tttatgaaca tcgtgacaag actaaagagg gaattagttt tacatccaag tatattttac
     4021 aaacagcagt ggttttgctt ggttttggat taaacctaac ccaagttatg gcagtgggca
     4081 tgcagtcttt accgattatc atttcaacta ttgcgacagc tcttttggta gcttatggct
     4141 cacagaaatg gctgcgcata gatgtcaata cagccacctt ggtgggtgta gggtcttcca
     4201 tttgtggggg gtctgctatt gcagcgacag ctcctgtcat taaggcaaag gatgacgagg
     4261 ttgctaaggc aatttcagtc atttttctct ttaatatgtt agcagctttg ctatttccaa
     4321 gtctaggaca attactgggc ttatctaatg aaggttttgc tatttttgct gggacagctg
     4381 ttaacgacac ctcttcagta accgcgacag caacagcctg ggatgccctt caccattcca
     4441 atacactaga tggcgcaacc attgtcaaat tgactcgcac cttggctatt cttccaatta
     4501 ctttaggctt atccctttac cgagcgaaaa aagagcacga catcgttaca gaagaaggct
     4561 tcagccttag gaagtcattc cctcgcttca tcctcttctt tttattagct tccctcatca
     4621 cgacattgat gaccagtttg ggtgtttctg ccgatgtttt ccattcccta aaaaccttat
     4681 caaaattctt tatcgtgatg gctatggcgg ctatcggttt aaacacaaac ttggttaaac
     4741 tgattaagac gggcggtcag gctatccttt taggggctat ttgctgggta gctatcaccc
     4801 ttgtcagttt agccatgcaa ttaagtttgg gcatttggta atcagacacg agaaatcagt
     4861 ttgactgatt tctttttttg tatcttattt gtgtagaatt gtctacattt taaagagaat
     4921 aatgcatttt aaaaacgttt tcatttggta aaataaacct atcgttaaac cagttcagta
     4981 aagacaactg gttgagataa gcaattaccg tttattcagc ggtttttgtt aatagaggag
     5041 gataggaatg aaacgaaaat ttctcatcgg gagtcacggc agactagcca gtggtttgca
     5101 aagctctatt gacattttag caggtatggg acaggcactt gaaaccattg atgcttatgt
     5161 tgatgatagt gactacacta gccagattga tgactttatc gctggggtag cagcagatga
     5221 gcagggcctt atttttactg atttgttagg cggcagtgtg aatcagaaaa tggtaaccgc
     5281 tgtaatgaac agtggcaaag acaatatctt tttaatcaca aacagtaact tagccacttt
     5341 attgtcgttg gtgtttttaa aaccaggcga agcgcttact aaagatgaaa ttgtaaccgt
     5401 tatcaatgaa tcgcaagttc agttagtgga tttggtccct gagacaaatt cagaagatga
     5461 cttttttgat taatatctag gaggaagaca aatgattact caaattcgtg ttgacgaccg
     5521 tttgattcac gggcaagtgg cagttgtatg gaccaaagag ttaaatgcgc cgcttttagt
     5581 agtggctaat gatgaagctg caaaaaatga aatcacacaa atgacgctta aaatggctgt
     5641 gccaaacggc atgaaactgc ttattcgttc agttgaagac tcgattaagc tctttaatga
     5701 tccacgcgca actgacaagc gtatttttgt gattgtcaat tctgttaaag atgcttgtgc
     5761 cattgctaaa gaagttccag acttagaagc tgttaatgtg gctaatgtgg ggcgttttga
     5821 caaatcagac ccagcaagca aagtcaaagt gacaccaagt cttttactta acccagaaga
     5881 aatggcagcc gcaaaggaat tagtcagttt accagaactt gatgtcttta accaagtctt
     5941 accatcaaat accaaggtcc atttgagcca attagtcaac taaagagagg taaaaaagta
     6001 tgttagtacc agcaacaatg gcagctttag ctgtattgat ttgttttggg ggaaattatt
     6061 taaccggtca aagtatgatg gaaagacccc tagtagttgg actggtcaca ggtcttcttt
     6121 taggagatat gaaggtcggt atcttaatgg gggcctctct agaagctctt ttcctaggaa
     6181 atgtgaatat tgggggtgtt attgcagctg agcctgtaac agcgactgcc atggcaacaa
     6241 cctttaccat tatttcacat attgaccaaa aagcagccat gaccctagct gttccaattg
     6301 gaatgttggc agcctttgtg gttatgtttt tgaaaaacgt cttcatgaat atctttgctc
     6361 caatggttga taaagctgca gcagctaacc atcaaggtaa actagtgatg ctccactatg
     6421 gcacttggat tatctattac ttaatcattg cctctatttc tttcattggt attttagtag
     6481 gtagtggacc tgttaatgcc tttgtggaac acattcctca aaatctcatg aatggcttga
     6541 gtgctgcggg aggccttctt ccagctgtcg gttttgccat gctgatgaaa ttattgtgga
     6601 ccaacaaatt agctgttttt tacctattgg gttttgtctt aacagcttat ttgaaattac
     6661 cagcggttgc agttgctgcc ctaggagcag ttatttgcgt tattagttcc caacgtgatc
     6721 tagaattaga cgcaattact agaggtgcaa ttagtaaaca aacaaccttt gactctaaag
     6781 aatcagaaga ggaggacttc ttcgcatgac atcacaagat aatttgacta aagaagaccg
     6841 caaaatgctt cgctcagtct tttggcgctc atggacgatg aatgctagtc gtactggggc
     6901 aacacaatac cacgcagtag gggttattta cactttacta ccagtcatca atcgttttta
     6961 taagactgat aaggataaag cagaggcact ggtccgtcat acaacatggt tcaatgccac
     7021 catgcacatc aataacttta tcatgggtct tgtggcatcg atggaaaaga aaaacagtga
     7081 agatcctgat tttgatgcta gtgctatcac cgctgttaag gcttcgttga tgggacctat
     7141 atctggagtt ggagattcct tcttctgggg aattttaagg gttattgcgg caggtatcgg
     7201 gatttccttg gcaagtgcag gctcagccat gggagctgtt gtcttcttac tcttgtacaa
     7261 tattcctgct tttattattc actactatag cctttatggt ggttattctg taggtgcagg
     7321 atttatcaaa aaactttacg aatctggtgg tataaaaatc gtcactaaaa cctcaagcat
     7381 gcttgggtta atgatggtag gctcaatgac ggcttcaaat gtaaaattta aaacgattct
     7441 tacagttgct gcgaaaggtg ccaaagaagc agcttctatt caagattacc ttgaccaatt
     7501 gtttattggt attgtaccat taatggtaac actagcagct ttttggcttc tacgaaagaa
     7561 agtgaatatc aactggatta tgtttggtat catgttcctt ggcattatcc ttggactttt
     7621 aggtatttgc taataatctc ctagcaatga aggtaagtaa gacaagtttt cttgttttgc
     7681 ttaccttttt ccttttaaga tgatgagact tgttttgatg aaaaacgtag tagcattaag
     7741 aaatttgtta taatgaaagg agcttaagat gcgaggtgaa caggtggaag aacattttaa
     7801 aaaacaatta caagatgata tttctagaca tttttcgtac caatcgttaa tgttatcatt
     7861 gttgctaatt ggtcttttta ttattttttc attagcgcca caacaattag gcctctatcg
     7921 tgatatcaat gccactgcaa cccgttatca ccgtttgatt agcaaacaag aagccttgct
     7981 ggatgactta gggaaaaata gcttactacc ttttttaaat aaaaacctca gcactgctga
     8041 tttaagcaag cactattttc atttgcgcca tagcagccaa acgtcaccag aacttttact
     8101 attttcacct aatcaaggcc ttttatttgc tagtaaccca catttaggaa atgtttttag
     8161 taaatctgtt tatattcaag aagtcttgag agcagctcat cctccaaaaa ccttgtttaa
     8221 agttgctatg gatagtgaag atggtcacta cttgatgatc attaagccaa tgatagatca
     8281 aaaccaacta aagggatatg cttttttagt gatgagtggt aaagattttc ttcatcctgc
     8341 aaaaacattg acgtcagagt tggtcattgc tgataagctg gacaatacgt ttacgttttc
     8401 caatcgtgag tttatagcat ctagtctaga taagatcaac agtcagtatt tacaccatta
     8461 ttttgttttt caagataatc gagcctttat cacaagaaag gttgccttac aaggaggtct
     8521 ttggctttac atgtataggc ccttgattcc aatggtatcg gtgatgttat tttcacttat
     8581 ttcatcagct gttatctttg tgattttgca acgtaaatca agtggtttag ctaaccgaat
     8641 tgcagctaaa aattcaagag caatcaatca aatggttaga gatatgagtg cgatctctcg
     8701 gcaagaaaaa agacgtattg accttgagag tcaagatgaa tttcaatatt tatctgatca
     8761 aatcaatcaa atggtagagc gattgcaaca gttacatgat aaaacgttag atttggaaac
     8821 tcaaaaatta ttatttgaaa aacggatgtt agaagctcaa ttcaatccgc atttcctcta
     8881 caatacgcta gaaaccattt tgattacgag ccattatgat tctgccctaa cagaaaaaat
     8941 tgttatccaa ttgacaaaat tgttgcggta tagtctcacg gattctagca aacctgtctt
     9001 gctcaaagat gatttaagtg tcatcgagtc ttatttagtg attaatcagg tacggtttga
     9061 agaattgcaa tatagcatta acctatcccc agacctcgat agtcttgcag tgcctaaatt
     9121 gttcttgtta cctttgatag aaaatgccat caaatatggc ttgaaagaac gacacgatgt
     9181 caagattaac attgcttgtt attatcaaga tgaccacatt attttttctg tgagagataa
     9241 tggttcggga attgatgctc atcaccaaaa agtgattcga gagcaattgg aagctggaga
     9301 gtcacaccat gggttaatta actcttatcg tcggcttaag tatcattttt cagaagtatc
     9361 cttggttttt gatcaaggtg ataaacagtt taatgttagc taccatgtta aggagtagtc
     9421 tatgtacaaa ttagtcatta ttgaagatga acatattatt aggaaatggt tgcgatacgc
     9481 tattgattat aaagctttag atattttggt cattggcgag gctaaagatg gcaaagaagg
     9541 agctgtttta atcaaagaga gtcaaccaga tatcgtttta accgatatta acatgcccat
     9601 catgacagct tttgacatgt ttgaagcaac aaaagatcaa acttacgcca aaattatttt
     9661 atctggctat gccgattttc caaatgcaag gtctgccata cactacggtg tacttgaatt
     9721 tttaacaaaa ccgattgaaa aagcagctct ttgggaatgt cttcaaacca ttattgctaa
     9781 aatagaaaag caaaaggggt ctaatcaaaa aacagatgct tgcgtctata ttcccttacc
     9841 ccagatgact gatcagattc ctgaagtagt caaagatatt ttggagtggg tacatgctca
     9901 ttttcaagac aagatcagca cgagccgcct agctcatgac ttagggtata gtgagagtta
     9961 tatctatcaa aatatcaaaa agcatcttca gatgccttta agtgattaca ttaatcaata
    10021 tcggattaat caggcaattc aattgatgca acaagaacca gatttaatgg tatatgaaat
    10081 agcacaagct gtaggtattt atgactatcg ctattttgat agggttttta aaaagtatct
    10141 aggacaaact gtaaaggctt ttaaagaaga gcattttatg aaagataccg ataggagtaa
    10201 gccatgttaa aactcaaacg caaatggcta ttaagctttt tgttagtaat aattatttta
    10261 gcaatcgtta acgttgcaat gtgtatattc tcatcgtcaa aaaaagatag tgctaaagaa
    10321 ttagttatct tgactcctaa tagccaaact attttaacag ggactattcc agcctttgag
    10381 gaaaagtatg gggttaaagt aagattaatc caaggtggga cgggccaact tattgatcaa
    10441 ttaggtcgaa aagataagcc attaaacgct gatattttct ttggtggcaa ttacactcaa
    10501 tttgaaagcc ataaagattt atttgaatcc tatgtttctc cgcaggtttc tactgtcatt
    10561 tcagattacc aattgcctag tcatcgtgca accccatata cgatcaatgg cagtgtactg
    10621 attgttaata acgaattagc aagaggactt catattacca gttatgagga tttgctacaa
    10681 ccagctttaa aaggcaaaat tgcttttgct gacccaaata gctcatctag cgctttttca
    10741 caattaacaa acatcttact ggctaaagga ggctatacga gctcagaagc ttgggagtat
    10801 gtgaaacgtt tattactgtc tatgaattct atcagagcaa caagttcttc agatgtttac
    10861 gaatctgttg cagaaggtaa aatgattgtt ggtttgacct atgaagatcc ttgcatcaat
    10921 ctgcaaaaaa gcggtgcaaa cgtttcgatt gtttatcctg atgaggggac agtatttgtt
    10981 ccgtcatcag tcgctattat caaaaaagca aaggcaatga aagaagctaa gcaatttatt
    11041 aattttattt tatcatcaga tgtacaaaat gcctttgggc agtcaactag taatagacct
    11101 atccgacgag atgctcaaac aagtcatgaa atgaaaccat tagatgaaat tattacttta
    11161 aaagaagatt acggatatgt tactagacat aagaaaaaaa tattgaatac ctataatcga
    11221 ctacatgaag cattagaaag aggaaagtag actctaggct tgttgttgct atactagtag
    11281 tgttacaaaa tagcgtagtc attttttgaa atcgatttca taatctggta gactaaggtt
    11341 atcacgaaaa ggaggctata tgtgatgact tatcaaacta tttaccctta tacaaatgaa
    11401 gtccttcata catttgataa tatgaccgac caaggtgtgg cagatgtcct tgaaagagct
    11461 caccttctct ataaaaaatg gcgcaaggaa gatcatttag aagaacgtaa agcccagctt
    11521 catcaagtgg ctaatattct tcgccgtgac cgcgataaat atgctgaaat catgaccaaa
    11581 gacatgggaa aactgttcac agaagcccaa ggtgaagtag acctttgtgc cgatattgct
    11641 gattactacg ctgataaggc agatgaattt ttgatgtcta cgccactaga aacagattca
    11701 ggtcaagctt actatttgaa acaatcaact ggtgttattc tagccgttga accttggaat
    11761 ttcccttact atcaaatcat gcgggttttt gcgccaaact ttattgttgg gaacccaatg
    11821 gttttaaaac acgcgtccat ttgcccacgc tctgcccaat ctttcgaaga attagttctt
    11881 gaagctggtg ctgaagcagg tagtattacc aatttgttta tttcttatga ccaagtatca
    11941 caagtgattg ctgataaacg tgtggttggt gtctgcttga caggttccga acgtggagga
    12001 gctagcattg cagaagaagc tggtaaaaac ttgaaaaaaa caacccttga attgggtgga
    12061 gatgatgcct ttattatctt tgatgacgcg gattgggatc aattagagaa ggtgctttac
    12121 ttctctcgtc tctacaatgc aggacaagta tgtacctcat cgaaacgttt tatcgtgctt
    12181 gacaaagact atgaccgttt caaagaatta ttaacaaaag tcttcaaaac agctaaatgg
    12241 ggtgacccaa tggatcccga aacgacgttg gcgccattat catcagctca agctaaagca
    12301 gatgttcttg accaaattaa gttggccttg gatcatggtg cggagttggt ttatggtggt
    12361 gaagcgattg atcatccagg tcattttgtc atgccaacca ttattgctgg cctcacaaaa
    12421 gacaacccta tttactatca agaaatcttt ggcccagtcg gtgaaatcta caaagtgtct
    12481 tctgaagaag aagcgattga agtggcgaat gattctaact atggccttgg aggtactatc
    12541 tttagtagca atcaagaaca tgcgaaagcc gtagctgcta aaattgaaac tggtatgtct
    12601 tttatcaact caggttggac aagtcttcca gaactcccat ttggtgggat taaacattca
    12661 ggctatggtc gtgaattgag tgagcttggc tttacatctt ttgtgaatga acaccttatc
    12721 tatattccga ataaaacgaa taatagcaat actaaagttt gatctagatt gttaaaggag
    12781 atctgctcgc cttaataaac aatcaaggcg ttacactctt cttttttaaa gtcaaaattt
    12841 taaaaatttg ataaactagt aacatgaacg aactgattaa acataaacta gaactcttac
    12901 cagacagccc tggctgttac ttacataaag ataaagaagg aactattatc tatgtcggta
    12961 aggcaaagaa tttgaaaaaa cgcgtccggt cctattttcg tgggagccat gataccaaaa
    13021 cagagttact agtatctgag attgtagatt tcgaatatat tgtaacagag tcagataccg
    13081 aagcgctttt gttggaaatt aacttgattc aaaaaaatat gcctaagtac aacatcaagt
    13141 taaaagatga taaatcttat ccctttctca aaatcacaaa tgagtctttt cctcggttag
    13201 tgattacaag atatattaag aaaaatgatg gattgtactt tgggccctac ccagattctt
    13261 acactgctaa tgaagttaaa aagttattag ataggatttt tccatttaaa aagtgtaaaa
    13321 atcctatcaa taaggtctgt ttttattacc atttaggcca gtgctgtgct cataccattt
    13381 gtcatacaga caaggcctat tgggatcgtt taattgatga tgttaagcac tttttaaatg
    13441 gtaaagatga caaaattatt gaagatcttc gttctaagat gttagcagct tctgaagaaa
    13501 tggcatttga acgtgccgct gaatatcgag atttgatttc aggtattgcc accatgcgca
    13561 ccaagcagcg ggtgatgagc aaggatttgc aagatagaga tatctttggc tattatgttg
    13621 ataagggatg gatgtgtgtc caagttttct ttgtgcgtca agggaaatta attcagcgtg
    13681 atgttaacct ttttccctat tataacgatg cagaagaaga tttcttaact tatatggggc
    13741 aattttacca agataaacag catttcatcc ctaaagaagt ctttattcca gaagctattg
    13801 atgaagaact ggtagccgct attgtgccaa ccaaaatcat caaacccaaa cgcggtgaaa
    13861 aaaaacaact ggtagctttg gctactaaga atgctcgtgt tagtctgcaa caaaaatttg
    13921 atttattaga aaaagatatc aaaaaaacga gtggtgctat cgaaaattta ggtcagttac
    13981 ttaggattga caagcctgtg cgcattgaag cctttgataa ttctaacatt caagggacaa
    14041 gtccagttgc ggctatggtt gtttttgttg atggcaaacc tagtaagaaa gattatcgta
    14101 aatttaagat taaaacagtg gtgggaccag atgattatgc cagtatgaga gaagtgcttt
    14161 ttcgaaggta cagtcgggtg aaaaaggagg gactgcaagc tcctaacttg attattgttg
    14221 atggaggcgt tggacaagtc aatgtggcca aagatgtgat agaaaaacaa cttggactca
    14281 ctattcctgt tgcgggactt caaaaaaacg ataagcacca gacccatgat ttgctttttg
    14341 gaaacccgct tgaagttgta ccgttgccgc gccgttctga agagtttttc ttactgcatc
    14401 ggattcaaga cgaagtgcat cgctttgcag ttacatttca tagacaagtg cgacgtaaaa
    14461 attctttttc atcaacatta gatcatattt cagggcttgg cccaaagcga aaacagttat
    14521 tactaagaca ctttaaaacc ataacagcga ttgcatcagc tacctctgag gagattcaag
    14581 ctttaggtat acctaaaaca gtagttgaag caatacagca acagataaca gacaataaaa
    14641 atgatagatc gtctccttaa ataagtgtta tgttttcagt actgatgagg taaaaaggcg
    14701 ctacttgtta cgcacgacat ttcagttcgt tattttgaaa ctttcagaaa gttgcgaagt
    14761 gtagtgagtt gatgatttta aaaactattt tatggtaaaa taaaatggta taaaaaaaac
    14821 agatttagat aggaagtttt gaaatgaaat ttctagagtt aaacaaaaaa cgccatgcca
    14881 ttaagacctt taatgaccag ccagttgact acgaggattt gcgaacagcc attgagattg
    14941 caaccttagc acctagtgcc aataacattc aaccttggaa atttgtagtc gttcaagaga
    15001 aaaaagctga gttagcaaaa gggttacctc tagcaaataa agtgcaggtt gaacaggctc
    15061 aatatgtagt ggcgctattt tcagacactg atttagcttt acgttctcgt aaaattgccc
    15121 gtatcggtgt caaatcatta ccagacgact taattggtta ttatatggag actttgccac
    15181 cacgttttgc tgcctttaat gaggttcaaa ccggtgagta cttagctatt aatgcaggca
    15241 ttgtggctat gaacttggtg ttatccttga cggatcaaaa gattgcttcc aatattatcc
    15301 ttggttttga taagtcaacg accaatgaga ttttagacat cgatccgcgt tttcgtccag
    15361 aattattgat tactgttggc tatagtgacg agaaaccaga accaagttat cgtttgcctg
    15421 ttgatgaagt catcgaaaga agatagagtc aggacaatta gttaaatgta atgtccagat
    15481 gcgctacgga gcgaccacta ttgttagact gatactattt tggcttattt taagttaaac
    15541 attatcccta aaacgaataa ggagagtata atgacaacca ttgattttaa agcagaagtt
    15601 gacaaacgta aagaagccat gttagcagat ttagttgacc tattacgcat caattcagaa
    15661 cgcgatgaca cattagctga tgacaaacat ccctttggac caggaccagt taaggcttta
    15721 gagcatttcc tcgcaatggc tgagcgtgat ggctacaaaa cgcgtaatat tgataactat
    15781 gcaggtgact ttgaatttgg tcaaggtgat gaagtactag gaatctttgg tcaccttgat
    15841 gttgtgccag ctggtagcgg ttgggataca gacccttatg agccagtgat taaagacgat
    15901 cgcatctatg cgcgtggatc ttcggatgat aagggaccaa ccatggcgtg ctactacgct
    15961 ctgaaaatca ttaaagaatt gggtcttcct gtgtctaaaa aagttcgttt cattgttggt
    16021 accgatgaag aatctggctg gggggatatg gattattact ttgcccataa cggtttgaaa
    16081 aatccagact ttggtttctc accagatgct gaatttccaa ttatcaatgg tgaaaaagga
    16141 aatatcaccg aatacctcca tttcgctggt gacaacaatg gtgcttttgt gcttcatcgc
    16201 ttccaaggtg ggttgcgtga aaacatggta ccagaatctg caacagctgt catcacgtca
    16261 ccgcatgacc ttgatgtgct agaagcagct ttggagcaat ttttatcaga acatggtgtt
    16321 aaaggttcta tgaaggctac tgatggtaaa attgaagtaa ctattattgg taagtctgct
    16381 cacgggtcga ctccagaagc gggtgttaat ggtgccacct tgttggctaa attcctgaat
    16441 caatttacct ttgaaggggc tgctaaggat tatttatatg tggcaggtga ggtgcttcat
    16501 gaagactttg cggcagaaaa actaggcctt gcttataccg atgaccgtat gggagccctg
    16561 agcatgaacg caggtgtctt cacctttgat agtcaatcag ctgacaatac catcgccttg
    16621 aatttccgct atccaaaagg aactgatgcg gcaaccctaa aagcaggatt ggaaaaatta
    16681 ccaggagtaa ttaaggtaag cctttctgag cacgaacata cacctcatta tgtgccaatg
    16741 gatgatgaat tagtagctac cttacttgct gtttacgaaa aacaaacagg tcttaaaggc
    16801 tacgaacaag ttatcggcgg aggaaccttt gggcgcttgc tagaacgtgg tgtggccttt
    16861 ggagcaatgt tcccaggtga tgaaaacact atgcaccaag ctaatgaata tatgccttta
    16921 gaaaatattt atcgctcagc agctatttat gctgaagcaa tctacgaatt aattaaataa
    16981 gatgcttatg acagcaaaaa gagctggaac actgttccag ctcttttgtg atgattagag
    17041 actgttgtta tttaccaaga cagaattgac taaagagttg ggtaatgagt tcatcaggag
    17101 cagcatcccc tgtgatttct ccgagaattt cccaagttct ggttaaatca acctgtagta
    17161 aatcaactgg catgccaagc gccaagccgt cattgacagc ttctaaactc tggactgcct
    17221 tttcaatcaa agaaatgtgg cgggcatttg acaggtaagt ggcatcttgt tctactagtc
    17281 cagcattatc aaagaagagc tggttgatac gatcttcgat cagattaatg ttctgattgg
    17341 ttaacaccga aataggaata aggtccgctg gcaactgttc caattcaatc ttttgttcca
    17401 aatctgtttt attcagcaat ataatgcggt tactgtcctg actgagattt aacaaagctc
    17461 ggtcttggtc agtcagtttt tcagaagcat tcagcacaag aagaacaagg tcagcttctt
    17521 gaagagcttt tttagaccgt tcaactccga tttgttcgac cagatcatct gtctcacgaa
    17581 taccggccgt atcgacaagt tttagaggaa ctcccttgat attaacgtat tcttcaatga
    17641 catctcgggt ggttcctgca atatcagtca caatagcctt gtcttctcgc aacaaattat
    17701 taagtaagct tgacttaccg acgtttggac gaccaataat agctgttgat aagccctcac
    17761 gcagaatttt accgcgttta gctgttcgaa ggagattttc caaaaggctt tggaattctt
    17821 gtgttttctc acgtagcaga gcagtggtca tttcttccac atcgtcgtat tcagggtagt
    17881 caatattgac ttcgacttga gctaaggtgt tgagaatttc ttgtcgggtg tcattgataa
    17941 gctgggaaag ggagccatcc agttgcttga ctgcaatcgt catagccttg tctgttttgg
    18001 cacgaataat gtccatgaca gcctcagctt gagtcaaatc aactcgccca tttaagaagg
    18061 cacgtttggt gaattcgcca ggctctgcca ttctagcgcc ttggcgaatc aatagttgca
    18121 agatttcatt tgtcacagca ataccaccgt gcgtattgat ttcaaccaca ttttcacggg
    18181 taaaggtttt gggggctagc atgactgaca ccataacttc atcgataata gttcctgttt
    18241 taggatcaat gatatggcca tagttaatag tgtgtgaggc gacttgctct aagttctttc
    18301 ccttaaaaac agattgtgca atggcaagcg catctgtccc tgatagacga acaatgccaa
    18361 tagctccttc accaagaggg gttgaaatgg cggtaattgt atcaaattct ttagttatac
    18421 tcatgccctc tattttaaat caagtcctag tagaaagcaa ggtattattt tgtatagaaa
    18481 ataggactag caccattttg agtttagcta atactaaaaa agaataaatg taaaaaaatc
    18541 atttttttaa taatttttat t
//
LOCUS       DAUGUF010000035        16128 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUGUF010000035 DAUGUF010000000
VERSION     DAUGUF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16128
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.035"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(162..1475)
                     /locus_tag="VIB71_001392"
     CDS             complement(162..1475)
                     /locus_tag="VIB71_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEQ8823123.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASSAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWPVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(1450..2409)
                     /gene="nrdF"
                     /locus_tag="VIB71_001393"
     CDS             complement(1450..2409)
                     /gene="nrdF"
                     /locus_tag="VIB71_001393"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ8823124.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(2731..4890)
                     /gene="nrdE"
                     /locus_tag="VIB71_001394"
     CDS             complement(2731..4890)
                     /gene="nrdE"
                     /locus_tag="VIB71_001394"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ8823125.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFITELAGIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPINGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQAEDWKALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYATATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(4910..5128)
                     /locus_tag="VIB71_001395"
     CDS             complement(4910..5128)
                     /locus_tag="VIB71_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEQ8823126.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            5521..5784
                     /locus_tag="VIB71_001396"
     CDS             5521..5784
                     /locus_tag="VIB71_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEQ8823127.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            5789..7522
                     /gene="ptsP"
                     /locus_tag="VIB71_001397"
     CDS             5789..7522
                     /gene="ptsP"
                     /locus_tag="VIB71_001397"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEQ8823128.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAIFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            7707..9134
                     /locus_tag="VIB71_001398"
     CDS             7707..9134
                     /locus_tag="VIB71_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ8823129.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAVKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            9230..10504
                     /locus_tag="VIB71_001399"
     CDS             9230..10504
                     /locus_tag="VIB71_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ8823130.1"
                     /translation="MKKLNVILVGLLSILMLSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSDLVIKAVKHIKKDQKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPKLQ
                     SSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVKDLVSGHLERIQ
                     EEVEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPD
                     FLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIG
                     SKVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQRQVNMTNQAIEKACGKKPR
                     YLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDI
                     HQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(10615..11700)
                     /locus_tag="VIB71_001400"
     CDS             complement(10615..11700)
                     /locus_tag="VIB71_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8823131.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            11798..12424
                     /gene="udk"
                     /locus_tag="VIB71_001401"
     CDS             11798..12424
                     /gene="udk"
                     /locus_tag="VIB71_001401"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEQ8823132.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            12504..12767
                     /locus_tag="VIB71_001402"
     CDS             12504..12767
                     /locus_tag="VIB71_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEQ8823133.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(12820..13629)
                     /locus_tag="VIB71_001403"
     CDS             complement(12820..13629)
                     /locus_tag="VIB71_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEQ8823134.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            13774..14271
                     /locus_tag="VIB71_001404"
     CDS             13774..14271
                     /locus_tag="VIB71_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEQ8823135.1"
                     /translation="MNKSKKIEQYQLMIEQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMTEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            14271..15956
                     /gene="dnaX"
                     /locus_tag="VIB71_001405"
     CDS             14271..15956
                     /gene="dnaX"
                     /locus_tag="VIB71_001405"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEQ8823136.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGLAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAKEEGVALPSGLSSDVTTEVEGLKRELNQLKQALAQLQASPS
                     PSHAPVKPAQAKPKLTTYKIDRVKILKIMEETVQDSQQSRQYLDALKTAWNEILDSIS
                     AQDRALLMGSEPVLANSENAILAFEAAFNAEQAMKRTDLNAIFGNIMSKAAGFSPNIL
                     AVPKADFHHIRSEFALQLKTQKASDPTEETIEETLEIPEGFDFLVDKINAVED"
BASE COUNT         5182 a         2795 c         3327 g         4824 t
ORIGIN      
        1 ctcttcctca aggatgagtt ttacagcaga gagtttgaag gctttatcaa aggtttttct
       61 tggcataatg actattcctc gttttcactt aattttgtgt ctactttagt ataccaagtc
      121 caattcatcc gaagcttttt attaaaaaag taattaacta atcatttaag gatgaaacga
      181 taaaactgat agctaaaata aaaaatgagg ttagctaatg ctaaagggat aatcattagt
      241 aacgattggc ctgtaatttc aaccagaaaa actggtgccg ccaagggtat cttattgatc
      301 acacctaaaa agattgttgc accaaccata atggctaacg tatttgatag agacaaggga
      361 ataaggtact gactaaggat agctagtagt aagccactag cacctccaag catcatagaa
      421 ggagcaattt tacccccttt tgctccagaa gcaaaaacta aagagatagc gacagctttg
      481 gcaacaagta gccagctaat atagctcaga tgtggttctt catggagaaa aaagagtaat
      541 ccagctttgc catttcctaa aatctctggg aagaaaatgc tgagtcctgc gataaggcta
      601 aaagcgatga gaactttcgg aataaaccac tgacttttgg catcagcctt aggaaggtgt
      661 tccaaaagat gtttgtaagc gtgagcaaag agggaaagga taagaccagc caggacgggc
      721 caaataaggg ttcctagcgt ccaatgttgc tgaggcatta ggtattgaat ctcatgtcgg
      781 ccttgtaata aagcaactgt ttccacagcc acatagctcg ttaggcaggc agcgtatata
      841 tttttaaggg accaacggtt aagaatagct tccaagataa ataaaatagt ggctaaggga
      901 gcattgtaga cagcaccaag ggcagcgcta gaagcgcaag ctaataaaag tttttgatcg
      961 gcttttgaca agttgcatct ttggctccaa agagacgtca aggtaacagc gacttcccgt
     1021 gaagctcctt ctcggccgac aggagctccc atagatacgg tcgttaattg gagccaacca
     1081 tgccaaaact gtgtccaggg actaaatgag atgtcatctt gaatgatttg ctgaatagat
     1141 tgaatgtcct ttcctttttt agccaatagg tgccacccaa gacctgcaag aagtccagca
     1201 aagagaagtg aaagagctcg tctttgtggt ggaacgctag caatcatagt gctaaaagaa
     1261 ccttgactga atccaaaact gagggactga atcaggtgaa tggcttttgt taagataaaa
     1321 gcaacaaggc cagctgttaa acctgttaaa aagaggtaaa aggtcaagag taaaaagtgt
     1381 cgtttcataa gactattata acaaaagtta agaaaagaga ctgatagatt atcagtctcg
     1441 tgagcactat tagagtccat aattataatc gtcatcagac atagcttcta cagaaccaag
     1501 aagatagcca ttccctacct gtgagaaaaa gtcatggttt gatgttcctg ttgaaatacc
     1561 attcataaca attgggttaa catcgtttgc agtatctggg aataaaggat cttgtcctaa
     1621 attcataaga gctttgttag cattgtagcg taaaaaggtc ataacttcct cagtccaccc
     1681 tacgccatca taaagcgttt tggtgtattt ttcttcgttt tcatacagct gataaaggag
     1741 gtcatacatc caatcacgaa aattctcttg ctcatcttct ggtagttcgt taaaaccaag
     1801 ctggaatttg taaccgatat aagtaccatg tacagattca tcacgaataa ttagtttaat
     1861 gatttcagca acatttgcta gcttattatt tcccaaatag taaagagggg tgaaaaagcc
     1921 agaataaaaa aggaaagttt cgagatatgt tgaggcaact ttcttttgta aggcatctcc
     1981 attagcgtaa atgtcattga taatacgtgc tttttcttga agaaactcat tattattagt
     2041 ccactcaaag atctcttcaa tttctttttt ggtgtttaag gttgaaaaga tagacgaata
     2101 agatttagcg tgaacagatt ccatgaattg aatattgttt aagacagctt cttcgtgagg
     2161 agtgcgaaca tcagcacgaa tagcttcgac accagtttct gattgcatgg tatcaagtag
     2221 ggttaatcct ccaaaaacct tgccaacaag atctttttct tgaagagaaa gtttgcgcca
     2281 atcgtctaag tcatttgata aagggatacg ggtatcaagc caaaattgtt cggtcaactt
     2341 ttcccaagtt gacttgtcaa tgacgtcttc gatttcattc cagttaattg cttcataata
     2401 tgtagtcata gaaaaatgat ctcctaaaga gtagtaaagt gcgttaagga tatcgagata
     2461 aaccagtaga accgaccaaa gttctagtgg taataataag tttaaataga ttcaaaaggg
     2521 taacgaatga gttagtgagt ggtttaggca gatcgcctaa agcgactgcc gtagaagtaa
     2581 tagatgcttt agcatcatta gggcatatcg aggaattacg acacggagta aggaaagtcg
     2641 ataatacttt ccttacatag ttagtgagtg gtttaggcag atcgcctaaa gcgactgccg
     2701 tagaatttag catcattact tcttaaccaa ttaaatgaca caagattcac attggtttgc
     2761 gcccacttct tccccatcat ccgtaaaggt acggatatag tagatagatt taatgccttt
     2821 attgaaagcg tagtttcgta agatggataa atcacgagtg gtttgtttgc tttgtgtttt
     2881 ccactcataa agctccatag gcaactcact acgaaggaat agagttaatg acaagccttg
     2941 gtccacatgt tcggtcgcag tggcatagac atcaataact ttgcgcatgt ccatatcgta
     3001 agcagatgta tagtaaggaa tggtatccgt agacaaacca tttgcaggat agtagatttt
     3061 accaattttc ttttcttgac gctcttcgat gcgttgtgtg attgggtgaa tagaagcaga
     3121 gcagtcattg atataagaaa tagagccatt tggagcaact gctagacggt tttgatgata
     3181 aagaccatct ttttgaacgg cgtcgcgaag agctttccaa tcctctgctt gaggaataaa
     3241 gtgatcttta aagagacttt tgaccaaatc agattttgga acaaagtgtc ctgtaacgta
     3301 tttatcaaag taactaccat tagcgtactt agagttctca aagccaacaa aggtagtttg
     3361 gcgctcacga gcgatgttat tggattcgac caaggtccaa taattcagga gcataaagta
     3421 aatatcagta aactcgatgg attctggact gccatattca atatgatgtt gagcaaggta
     3481 agaatgtagt cccatagctc caaggccaaa agtatgagct tggctattgc catgtttaat
     3541 ggttggaaca gcttcaatgc ttgatgaatc agtaacaaaa gttagggcac gtgtcatggt
     3601 cttaatagaa cggccaaagt ctggtgaggt catcatgttc aggatattag tggaacctaa
     3661 gttacatgaa atatcagttc ccatttctac aaactcttgc gcatcattga taaggctagg
     3721 tgtttgaact tgtaaaattt cagaacacaa gttgctcatg atgatttttc cattgatagg
     3781 attagcttta ttagctgtat caatattgat gatataaggg taaccagatt cttgttgtaa
     3841 ttttgaaatc tctgtttcaa gatcacgagc tttaatttta gtcttagtaa ttttagggtt
     3901 tgccactaac tcatcgtaca tattggtaat gtcgagatag ttaaagggaa tgccatattc
     3961 tttttcaaca ttgtaaggac taaagagata catgtcctcg tttttacgag ctaattcgta
     4021 gaatttatca ggaacggtaa tccctagtga caaggtttta acacgtacct tttcatcggc
     4081 attttctttt ttagtagata agaaagcaat gatatcagga tgaaaaacat ttaggtaaac
     4141 aacaccagct ccttgacgtt gcccaagttg atttgaataa gaaaaactat cttcaaataa
     4201 tttcataaca ggaacaactc ctgaggctgc accagcatag cctttgattg gtgcgccagc
     4261 ttcacggagg ttagacaagg taatcccaac acctccacca atacgggata attgcaaagc
     4321 agagttgata gaacgtccga tagagttcat gtcatcagtt acttgaatca agaaacaaga
     4381 gaccaattca ccacgacggc ttcgaccagc atttaaaaag gaaggagtag ccggttggta
     4441 acgttggtta atcatttcaa cggctaaatc ttttgctaag tcttcttgac catctgcaaa
     4501 atacaaagca ttaaacaaga cgcggtcttc aaggttttct aaataatgct ctccatcatt
     4561 tgtttttaag gcgtattgct ggtagaactt gtaggctgcc ataaatgatt taaagcgaaa
     4621 attttctgat ttgattatgc cagctaattc agtaataaat tcagggtggt atttctgaat
     4681 aaaagctgat tcaatgtaat catttgagat taaatactca attttttccg taatggaagt
     4741 aaaagacatg gtgtttggca gcacattttc agcgaaaaaa gcttttaaag cttctttgtc
     4801 tttatgaagt ggaattttac cattaacagg acggttaatt tcattattta ggcgaaaata
     4861 tgaaatatcg ccaagatctt tgagactcat attatttttc cttgtcttat taaatcaatt
     4921 cttttaactt tgcaggttgg aagccagaaa atacgaggtt atctgcttcg ataacaggag
     4981 cagatgtgaa gccaagactt ttcacataat ccactttttc aggatgttca tcgatattaa
     5041 tttcctggaa gttggctccg tgttgttcta aaaatttctt agtcattttg cactgcatgc
     5101 aattattttt ggaatatact gtaatcatgt cttgtccttc taaaattagt aatggttcca
     5161 tcttaaatgg aattactata atagcatata aaaaataaag ctaaaaagca agctataaac
     5221 ttatctgaaa cacaacatat tgtgttgaaa taaaaaacag aaacctaaat attgtgtcaa
     5281 tctggattct tatggttaga gctctagcgt tttggtgata gaagctaagc agttttaata
     5341 aagcattaaa gtctgaaaaa taaattgtga aaaacgtgaa aataaaagaa aataatttca
     5401 cattttttgt cgtttaaata tttaatcttg aaaataaaaa agcattgtgc tataatcggt
     5461 tgttgtaagg gttatcatgt gatggctcaa aaatacacaa cttaaaagga gaaccatact
     5521 atggcttcaa aagactttca cattgttgca gaaacaggta ttcatgcgcg tccagcgact
     5581 ttgcttgttc aaacagctag caaatttgct tcagacatca ctcttgacta caaaggtaaa
     5641 gcagtaaatc taaaatcaat catgggtgtt atgagtcttg gtgttggtca aggtgcagat
     5701 gttactatct cagctgaagg tgcagatgct gaagatgcca ttgcagcaat tgaagaaaca
     5761 atgactaaag agggattggc ataagactat gacagaaatg cttaaaggaa ttgcagcctc
     5821 agacggcgtt gctgttgcta aagcatatct actagttcag ccggatttgt catttgagac
     5881 tgttacagtc gcagatacaa atgcagaaga agctcgcctt gatgttgcac tccaagctgc
     5941 acaagacgag ctttctgtta tccgtgaaaa tgcagtagaa agcttaggtg aagaagcagc
     6001 agccgttttt gatgcccatt taatggttct tgctgatcca gaaatgatca gccaggttaa
     6061 agaaacgatt cgcgcaaaac aaacgaatgc agaaacaggt cttaaagaag tgactgacat
     6121 gttcatcacc atctttgaag gcatggaaga taacccatac atgcaagaac gtgcagcgga
     6181 catccgcgac gttgcaaagc gtgtgttggc tcacctttta ggtgtaaaac ttccaaatcc
     6241 agctacaatc aatgaagaat caatcgttat cgcacacgat ttgacacctt cagatactgc
     6301 tcaacttaac aaacaatttg taaaagcatt tgttacaaat atcggtggtc gtacaagtca
     6361 ctcagctatc atggcacgta cacttgagat cgctgcggta cttggaacaa atgatattac
     6421 aaaacgtgtt aaagatggtg atgtgattgc cgttaatggt atcactggtg aagtgattat
     6481 cgatccaagc gaagatcaag tacttgcttt taaagaagct ggtgcggctt atgccaaaca
     6541 aaaagcagag tggtctctcc ttaaagatgc gcatactgaa acagctgatg gcaaacactt
     6601 tgaattggct gctaatatcg gtacgcctaa agacgttgaa ggtgttaatg acaatggcgc
     6661 tgaagctgtt ggcctttacc gtactgagtt cttgtacatg gattctcaag acttcccaac
     6721 tgaagacgaa caatacgaag cttacaaggc agtgcttgaa ggcatgaatg gcaaacctgt
     6781 tgtggttcgt acgatggata ttggtggcga caaggaactt ccttactttg accttccaaa
     6841 agaaatgaat ccattccttg gtttccgtgc tcttcgtatt tccatctctg aaactgggga
     6901 tgccatgttc cgcacacaaa tgcgtgcgct tcttcgtgcc tctgttcacg gacaacttcg
     6961 tattatgttc ccaatggttg cccttcttaa agaattccgt gctgcaaaag caatctttga
     7021 tgaagaaaaa gcaaacttgc ttgcagaagg cgttgcggtt gctgatgaca tccaagttgg
     7081 tatcatgatt gagattcctg cagctgctat gcttgcagac caatttgcta aggaagttga
     7141 tttcttctca attggaacaa acgaccttat ccaatacact atggcagcag atcgtatgaa
     7201 cgaacaagta tcataccttt accaaccata caacccatca atattacgtt tgatcaacaa
     7261 tgtgatcaaa gcagcgcacg ctgaaggtaa atgggcaggt atgtgtggtg agatggcagg
     7321 tgaccaacaa gctgttccac ttcttgtcgg aatgggcttg gatgagttct ctatgtcagc
     7381 aacttcagta cttcgtacgc gtagtttaat gaagaaactt gactctgcta agatggaaga
     7441 atatgcaaat cgtgcgctta cagaatgttc aacagcagaa gaagttcttg aactttctaa
     7501 agaatacgtt tctgaagatt aacgggttaa agagttggtt taaaccagct cttttttgct
     7561 agctaaaaat acaattactt tttggtgtga aatcatttga gttatcaaat aattatcaga
     7621 attttcagat atttagtgta gccaaatctt gaattatatc ggaaaagtga tagaataaga
     7681 ttactatcat aaaaggagat aaaacgttgg caaaacaata taaaaattta gtgaacggtg
     7741 aatggaaact atcagaaaac gagattacca tttacgcacc agcaacaggt gaagagttag
     7801 gatcagttcc agcgatgacg caggcagagg tagatgctgt ttacgcttca gctaaaaagg
     7861 ctctatcaga ttggcgcgcc ttgtcttatg tggaacgtgc agcttacctt cataaagcgg
     7921 ctgatatttt agtacgtgat gctgaaaaga tcggcgcgat tctttcaaaa gaagtagcca
     7981 aaggtcacaa ggcagctgtc agtgaagtta ttcgtaccgc tgaaatcatt aattatgcag
     8041 cagaagaagg gcttcgtatg gaaggtgaag ttcttgaagg tggtagcttc gaagccgcaa
     8101 gtaagaagaa gattgctatt gttcgtcgtg aaccagttgg tttagttctt gccatctcac
     8161 cttttaatta tcccgttaac ttggcaggtt ctaaaattgc tccagccctt attgcaggaa
     8221 atgttgttgc tcttaaacca ccaacacaag gctctatttc tggtttgtta ctagcagaag
     8281 cttttgcaga agctggtatt ccagcaggtg tctttaatac cattacaggg cgaggttctg
     8341 ttattgggga ttatatcgtt gagcacgaag cggttaactt tatcaacttt acaggttcta
     8401 ctccaattgg ggaaggaatt ggtaaattag cgggtatgcg accaattatg cttgagcttg
     8461 gtggtaagga ttctgctatc gttttggaag atgcagatct tgctttagca gcgaaaaata
     8521 ttgtagccgg tgcttttggt tactcaggac aacgttgtac agcggttaaa cgcgttcttg
     8581 tgatggacaa ggtggcggat caattggcgg ctgagattaa aacccttgtt gaaaaactaa
     8641 gtgtcggaat gcctgaagac gatgctgata ttacaccatt aattgataca tcagctgctg
     8701 attttgttga agggttgatt aaagatgcaa ctgataaggg agctactgct ttgacagcct
     8761 ttaatcgtga aggcaatctt atttcacccg ttctctttga tcatgtgaca actgacatgc
     8821 gtttggcgtg ggaagagccg ttcggcccag tattaccaat tattcgtgta accactgtag
     8881 aagaagccgt caagatttct aatgagtctg aatatggttt gcaagcttct atttttacaa
     8941 ctaatttccc aaaagctttt ggcattgctg agcaattaga agttggaact gttcacctta
     9001 acaataaaac acaacgtgga acagataatt tcccattctt aggcgctaaa aaatcaggtg
     9061 caggggtaca aggagttaaa tattctatcg aagctatgac aactgttaaa tctgttgtat
     9121 ttgatatcca gtaataaaaa aaaataaaca aaaagttagg ttaacttaac tttttgttta
     9181 tttttttaat gttttttgtt acaatagtct atacagatgg aggcaactat tgaaaaaatt
     9241 aaatgttatt cttgttggtt tattaagcat tctgatgttg agtttagcta ttgtgtttat
     9301 taatcgttgg aaactaaacg aagatagtca gcgtatagtt ttggctgaaa agaaaaaaaa
     9361 cacgtcagat ttagtgatca aagctgtaaa acatattaaa aaagatcaaa aagactatta
     9421 ttatttttcc ccgataaaac aagcagatga tttttttgta gataatttac ctgtttcatt
     9481 atacaaaaaa aagaattcag ataaagaatt gattttagta aagcctaaac tgcaatcttc
     9541 tcacctaaga tcagttaaca ctttgactat ttctaaaata gtttatcaga aaaaattttt
     9601 tcatttggct aaaaaatcag aaaaagttat aagtacatat cacgttacag acgatttgaa
     9661 accgtttcag gtaaaggatc tagtatcagg acatttagaa agaatacaag aagaagttga
     9721 aaaaaaatat ccaaatgctg gttttaatag cgataagtac aatggcttaa aagaatctaa
     9781 ttctttatta agcgatggct ttgaggtaaa atcgggaaac cttatttttg ataaaaagct
     9841 aacgatacct ttgacgacat tatttgatgt tattaatcca gattttttag caaatagcga
     9901 tagagctgcg tatgataatt ataggaccta caaagaacag catcccaaaa aactagttgc
     9961 attaacgttt gatgatggtc cagatccgac gacgactcct caagttttag atattttggc
    10021 aaaataccag gctaagggaa ctttctttat gataggttca aaagttgtga ataatgaaaa
    10081 ccttactaaa cgtgttagcg acgctggcca tgaaattgct aatcatactt gggatcatcc
    10141 caatctgact aatctttcag tcagcgagat tcaacgtcaa gttaatatga cgaaccaggc
    10201 tattgaaaaa gcttgtggca agaaacctcg ctatttacgc cctccatacg gagctacaaa
    10261 tgcaactgtt cagcaatcct caggattaac acaaatgctt tggacggttg atacaagaga
    10321 ttgggaaaat catagcactg atggcattat gactaatgtc aaaaaccaat tgcaaccggg
    10381 aggagttgtt ttaatgcatg atattcatca aacaactatc aatgctttgc cgacagttat
    10441 ggaatatcta aaagcagaag gatacgaatg tgtgactgta tcagaactct atgcgcatca
    10501 gtaagtaata tcgttatgtt tctttagaat tgatatacta aacaatccaa ttacttcaaa
    10561 agtaattgga ttgttgtttt tagtagccct tgattaagtt ttgtttttta acaactagtt
    10621 gatgaaatga agttgctgat ttttgaggga gatttcagag actttagcaa attttttcaa
    10681 ttttttgagg tcttcagggt ggctaacaaa ggtaataacg ataccagatt ttcccatacg
    10741 gccggttcgt ccagctctgt gagtgtaatt ttccttatca cgagcaacat caaaatgaat
    10801 gacatagtca agattatcaa tatcaatgcc ccgagcaaca agatccgtag ctaacaataa
    10861 ggagagttgg tgggatttga atttttcgag aatggtttta cggaatttga cattaatgtc
    10921 actcgctaag gaaaccgcag cagctccatt atactggaga cgttcttccg tagcacccaa
    10981 atcagataaa ctgttgaaaa agaccaaagc tctaaaatga ggaatattag caaattttcg
    11041 taataaatcg gtacgttcgc gcttgtcaac catgaggtaa aaatgctgaa tagcatcgtt
    11101 ggtttgctct gaaagatcga tgcagaatgt atttggagct aaggaagttt gatccacctt
    11161 attagtagca ctcatgtata ccatttgatg atctcgagga acatagtggc taattttttg
    11221 aacaaaatca tattgggaat cacctaataa ttcgtcatat tcatctaaaa caatggtgtt
    11281 gacagacatc atcttgattt tttttaattt aatcagttca aaaatgcgtc caggggttcc
    11341 aatcaggatt tcaggacctt ttttgaggcg ttcgatttga cgtttttgac tggttccaga
    11401 aataaagagt tgtgccgtta agcctagtgg ctgtgcccaa tcctttgtga cttcaaaaat
    11461 ttggccagct aattcggtat taggggctaa aatgagtagt tgttgggact ttttaggcgt
    11521 cagtgccaat agactaggaa agacataagc taaggtcttg cccgtcccag tagggctaat
    11581 accaaggaaa tttttaccat caacaatagg ttgaaaggcc tgttcttgga ttggcgttaa
    11641 atgggtaaat gcaacttggt caagtttttc ttgccattga gggggaaatt tagtgatcat
    11701 gcgtcttcct tttactattg tttctatatt cattatagca ttatagtctc aattttggta
    11761 aaatagtgag aaagactttt tagatttgga gtttaaaatg cttaaaaaac cgattattat
    11821 tggtgtaact ggtggttcag gtggcggtaa aacaagtgtg tcacgcgcta ttttggacag
    11881 ttttccaaat gctcgtattg cgatgattca acacgattct tactataaag atcagtctca
    11941 catgagtttt gaagaaaggg tcaaaaccaa ttatgaccat cctctagctt ttgatacaga
    12001 ttttatgatt cagcaactaa aagaattatt agctggtaga cctgtagata ttcctatcta
    12061 tgattacaaa aagcataccc gcagtaatac gacctttcgt caggatcctc aggatgttat
    12121 tattgttgaa ggtattcttg tcctagaaga tgagcgtttg cgagatttga tggatatcaa
    12181 gctctttgta gacacagatg acgatattcg tattattcgt cgtattaagc gtgacatgat
    12241 ggaacgtggc agaagcttag aaagtattat tgatcagtac acaagcgtgg taaagcctat
    12301 gtatcatcag tttattgagc caagtaaacg ctatgctgat attgttattc cagagggagt
    12361 tagtaatgtc gttgctattg atgttattaa tagtaaaatt gcgagtattc ttggagaagt
    12421 atagtggaag tggctgagta gattatttaa atctgctctt ttattgttgt gctcttccta
    12481 gagaaaggga tcataaaata gaaatgttat taatttggct tggattacta tttgtttgga
    12541 atgaactcgt gtttgtcata tatgcctttg ataaaagaaa agccataaaa aagaaacggc
    12601 gtattagtga aagaaactta ttagtgataa cagttttgtt tggaggtttt ggagcattac
    12661 ttgcagctaa aaagtaccac cataaaacca gaaagtggta ctttgtcatc acttggtata
    12721 ctagtatttt gttgacatta ctagtaactt atatctttat gaagtgagtc acttaaaaga
    12781 cccttaatca gtattattta gtcaaggctc ttttatagtt taaaaaagca catcatcgtc
    12841 aagggtgttg attttttgaa aaagatcacc aaagattaaa aggattaatg ttcctagtaa
    12901 aactgtcatg ccaggaatgc ttgttagagg agagttccag atgaaatgta gaaccagagg
    12961 acttaataac cagaaaattt gttgctgttt tgaaaaaagg ttagaaccct ttaataataa
    13021 gtatgctcca atggtaaaaa tagctgtatg tacccaatgt gaagtcacag cagtgctaat
    13081 acgttcaata gcagtcggta cgagactatc tatagatttt gcttgaatca aataacggat
    13141 atcttctgtt agttgaaagc ccatgccaga aagtaaagca acaactaatt tttctttaag
    13201 agtaagtcta ggaaataaag taattactaa aatagccgaa gaagccttaa tgggctcttc
    13261 gacaataggg gcagttaaag catctcccca aagctttaaa gcgtctttag aagggatgat
    13321 gtatgaccaa aattgtccta cgagatggtt cccacaagaa gctaaaaaac ctgaaatata
    13381 aagtccgcta agacagctaa caataataac gttcaggttc atatgaaatt ttttacttaa
    13441 ataaaaaata gctgctgcaa atggaattaa gtaaatgcct aatagactaa tggttagtat
    13501 tagagcaaaa gcttctttaa aggaaaggtt gttagctgtc agtcctaaca attcaagttc
    13561 aataccattt aaaactaaag caataaaaag accgtatcgt aaccatttct gttgagtgat
    13621 ttgtttcacg aaaacctcct aatattaagg tgatattaat aatattgaaa attatatcat
    13681 aaacaacctc aaaaaccatt ttaaaaactg actgaagcga aagatagtcg taaaaaatac
    13741 tcgaatagac ccagatatgc tataataaaa ggtatgaata agtctaaaaa aattgagcaa
    13801 taccaactaa tgatagagca ggcaaaagag ctgtttgcga atgaatcaaa tgctttggct
    13861 aatttgtcaa atgccagcgc cctgttaaac atgacactac ccaattctgt ttttgcggga
    13921 ttttaccttt ttgatgggca ggaattaatt cttggccctt ttcaaggtag ggtttcttgc
    13981 gtccatatca agcttggtaa aggtgtttgt ggcgaatcag ctcagtctcg tcgaaccatt
    14041 attataaatg atgtgaagca gcatgccaac tatatttcct gtgatgcggc agccatgact
    14101 gaaattgttg tgcctatggt gaaagaaggc catttgattg gggtgctgga cttggattct
    14161 agccttgtag ctgattatga tgaggttgat caagaatact tagaggcctt tgtggaccta
    14221 tttcttgaaa agaccacgtt tacctttaac atgtttggag ttaaaaactg atgtatcaag
    14281 ctctttatcg gaaataccgg agccaaacgt ttgacgaaat ggtgggacaa tcggttattt
    14341 ccacaacttt aaagcaggca gttgaatctg gcaagattag ccatgcttat ttattttcag
    14401 gtcctagagg gactgggaaa acaagtgcgg caaagatttt tgcaaaggcc atgaattgtc
    14461 ctaaccaagt cgatggtgaa ccctgtaatc aatgcgatat ttgccgagat atcacgaatg
    14521 gaagcttaga agatgtgatt gaaattgatg ctgcctcaaa taatggtgtt gatgaaattc
    14581 gtgacattcg agacaaatca acctatgcgc caagtcgtgc gacttacaag gtttatatta
    14641 ttgatgaggt tcacatgtta tcaacagggg cttttaatgc gcttttgaaa actttggaag
    14701 aaccgacaga aaatgttgtc tttatcttgg caacaacgga attgcataaa attccagcca
    14761 ctattttatc tcgtgtgcaa cgctttgaat tcaaagctat taagcaaaaa gctattcgag
    14821 agcatttagc ctgggttttg gacaaagaag gtcttgccta tgaggtggat gctttaaatc
    14881 tcattgcaag gcgagcagaa ggaggcatgc gtgatgcttt atctatttta gatcaggctt
    14941 tgagcttgtc accagataat caggtcacca ttgcaattgc cgaagaaatt acaggttcta
    15001 tttccatact tgctctgggt gactatgttc gatatgtctc ccaagaacag gctacgcaag
    15061 ctctggcagc cttagagacc atttatgata gtgggaagag catgagccgc tttgcgacag
    15121 atttattgac ctatctgcgt gatttattgg tggttaaagc tggcggcgac aatcaacgtc
    15181 agtcagctgt ttttgatacc aatttgtctc tctcgataga tcgtatattc caaatgataa
    15241 cagttgttac tagtcatctc cctgaaatca aaaagggaac ccatcctcgg atttatgccg
    15301 aaatgatgac tattcagcta gctaaagaag aaggagtagc gttaccatca ggtttgtcat
    15361 cagatgtgac gactgaagtt gagggactta aacgtgaact taatcagctt aagcaagcct
    15421 tggcacaatt gcaagccagt cccagtccct cacatgctcc tgtaaaacca gcacaggcta
    15481 aaccgaaact aaccacttac aagattgatc gggtgaaaat actgaaaatc atggaagaaa
    15541 cggttcaaga tagtcagcaa tcacgccaat acttggatgc cctaaaaaca gcttggaatg
    15601 aaattttaga cagtatctca gctcaagata gagccttact aatgggatca gaacctgttc
    15661 tggccaatag tgagaatgct attttagctt ttgaagctgc ttttaatgct gagcaagcaa
    15721 tgaagcgtac tgatttgaat gcgatattcg gcaacattat gagcaaagca gcaggcttct
    15781 cacctaatat tttggcagtc cctaaagctg attttcatca cattcgttct gagtttgcct
    15841 tacaattgaa aactcaaaag gcttctgacc ctacagaaga gacgatagaa gaaacccttg
    15901 agattccaga aggctttgat tttctagttg ataaaattaa tgccgttgag gattaaacat
    15961 tattagctgt taatgaacca gtaacgctat aaaggtaagc ctattgggct tacctttagc
    16021 gtttttttat ctaatatacc aagatagttt ttctagccaa tcctctaata gtagaagtga
    16081 aaccaaaaaa gattgatgct ttcttgggta tccaagtcag catcaatc
//
LOCUS       DAUGUF010000036        15989 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUGUF010000036 DAUGUF010000000
VERSION     DAUGUF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15989
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.036"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            96..1514
                     /locus_tag="VIB71_001406"
     CDS             96..1514
                     /locus_tag="VIB71_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ8823137.1"
                     /translation="MDKKIQRFSCTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMI
                     VVKPEDQPRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATE
                     TITTNSRVLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVA
                     FSDEHDIWWLETIGGHHWIARRVPDDAYVTNPNQFGIDYFEFNNPEDYLCSADLKDFI
                     DTYHLDLTYNHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWC
                     QKPYRKITVEDVKYVLSSHYQDTVYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRP
                     NKPQEIAAIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAAL
                     ADPHYNHHETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQ
                     TLLNKILFDASNLMTNRFSLSD"
     gene            1666..3213
                     /locus_tag="VIB71_001407"
     CDS             1666..3213
                     /locus_tag="VIB71_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEQ8823138.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGVGHDHHHEEADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            3361..4083
                     /locus_tag="VIB71_001408"
     CDS             3361..4083
                     /locus_tag="VIB71_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8823139.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKVGKTPKTEILS
                     FEQYQVTPYLSGLLEFDLDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILI
                     EFTFSIARADQFRYRVQHHPNG"
     gene            4103..5302
                     /locus_tag="VIB71_001409"
     CDS             4103..5302
                     /locus_tag="VIB71_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEQ8823140.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAP
                     DYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(5399..5659)
                     /locus_tag="VIB71_001410"
     CDS             complement(5399..5659)
                     /locus_tag="VIB71_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEQ8823141.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(5774..6715)
                     /locus_tag="VIB71_001411"
     CDS             complement(5774..6715)
                     /locus_tag="VIB71_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEQ8823142.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLTWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            7109..7558
                     /locus_tag="VIB71_001412"
     CDS             7109..7558
                     /locus_tag="VIB71_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEQ8823143.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSDQFALTGAVKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            7733..8017
                     /locus_tag="VIB71_001413"
     CDS             7733..8017
                     /locus_tag="VIB71_001413"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEQ8823144.1"
                     /translation="MRLEEIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQRLTGGDIND"
     gene            8010..9272
                     /locus_tag="VIB71_001414"
     CDS             8010..9272
                     /locus_tag="VIB71_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEQ8823145.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGATVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFAYLLGWFKPYLSQKLPNPYFRIAFIGALLSICLMIGHV
                     GRYSGLGTHLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            9387..9734
                     /gene="rplS"
                     /locus_tag="VIB71_001415"
     CDS             9387..9734
                     /gene="rplS"
                     /locus_tag="VIB71_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEQ8823146.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9981..10052
                     /locus_tag="VIB71_001416"
     tRNA            9981..10052
                     /locus_tag="VIB71_001416"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10014..10016,aa:Arg,seq:cct)
     gene            complement(10015..10329)
                     /locus_tag="VIB71_001417"
                     /pseudo
     CDS             complement(10015..10329)
                     /locus_tag="VIB71_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            10737..11306
                     /locus_tag="VIB71_001418"
     CDS             10737..11306
                     /locus_tag="VIB71_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEQ8823147.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            11307..13259
                     /gene="gyrB"
                     /locus_tag="VIB71_001419"
     CDS             11307..13259
                     /gene="gyrB"
                     /locus_tag="VIB71_001419"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEQ8823148.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNHGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            13651..15375
                     /gene="ezrA"
                     /locus_tag="VIB71_001420"
     CDS             13651..15375
                     /gene="ezrA"
                     /locus_tag="VIB71_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEQ8823149.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(15507..15965)
                     /locus_tag="VIB71_001421"
     CDS             complement(15507..15965)
                     /locus_tag="VIB71_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEQ8823150.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
BASE COUNT         4924 a         2816 c         3350 g         4899 t
ORIGIN      
        1 ataataagat aaggaggtgc tgctggaatt atgaaaattt ttgtatccag ttcaatggat
       61 atttgatata atcgtcttaa aaaggaggtc gtgaaatgga taaaaaaata cagcgttttt
      121 catgtacaac tatactcgtc ggtaaaaagg catcttatga tggctcaacc atggttgctc
      181 gaacagaaga ttctcaaaat ggtgatttca cgcctaaaaa aatgattgtg gtgaaaccag
      241 aagatcaacc gagacattac cgttcggtgc aatcttcctt tgaaatggac ttaccggaca
      301 atcccatgac ttacacgtct gttcccgatg cgcttggtaa agatggtatc tgggcagaag
      361 caggcgtgaa cgaggctaat gtggccatgt cagcaactga aaccatcact accaattctc
      421 gtgttttagg ggcagatcct ctagtagctt ctggtattgg tgaggaggac atggtgacct
      481 tagtgctccc ttatatccgt tctgcgcgtg aaggggtttt gcgccttggt gccattttag
      541 aagactatgg cacttacgag tcaaatggtg tggctttttc agatgaacat gacatttggt
      601 ggctggaaac gattggtggt catcactgga ttgcaagacg ggtgccagat gatgcgtatg
      661 tcaccaatcc caatcaattt ggcattgatt attttgaatt taacaatcct gaagattacc
      721 tttgctcagc tgatttaaag gactttattg acacgtatca cttagattta acctataacc
      781 atgagcattt taatccccgt tatgcttttg gtagccaacg tgacaaagac cgtcactata
      841 atacgccacg tgcttggatc atgcaaaaat tcttaaaccc agaaattgtg caagacccgc
      901 gcagctttgc ccttgcttgg tgtcaaaaac cttaccgtaa aataacagta gaagatgtca
      961 aatatgtatt gagtagtcac tatcaggaca cggtttatga cccttacggt tcagaaggaa
     1021 ctcctgttag taagaaagtc tttcgcccta ttggcattaa ccgtaccagc caaaccgcta
     1081 tcttacacat tcgtcctaat aaacctcaag aaattgcggc tatccagtgg atggcttatg
     1141 ggtcaatgcc atttaatacc atggtgcctt ttttcacaca ggtgaagact attccagatt
     1201 attttgccaa cacttacgaa aatgtgtcta ccgacaattt ctattggacc aaccgtctga
     1261 ttgcggcttt ggcagatcct cactacaatc atcatgaaac tgatttggac aattacttgg
     1321 aagaaaccat ggcaaaaggt catgccatgt tacatgctgt ggaagcacag ttattggctg
     1381 gtgaaacagt cgatttggaa gaggaaaatc aaaaaatgag tgactatgtg caaggagaaa
     1441 cgcagacgct gttgaacaag attctctttg acgctagcaa tctaatgacc aatcgtttca
     1501 gtttgagcga ttaaaagtga agctaaggct gagcaactgc ttagcctttt ttacgataac
     1561 tttttaggaa aagtaatcgc aaaaagacaa aaacttggaa aaaaaatcaa agtatgctat
     1621 acttaactgg tcaattttta accagttaat aacaaaggag gaatcatgaa aaagaaaatt
     1681 cttttaatga tgagtttaat cagtgtcttt tttgcttggc aacttactca ggcaaaacaa
     1741 gtcttagcag agggtaaagt gaaggtggtg acaactttct atcctgttta tgaatttaca
     1801 aaaggggtta ttggtaatga tggcgatgtt tccatgctta tgaaagcagg aacggaacct
     1861 catgattttg agccttctac aaaagacatt aaaaaaatcc aagatgcaga tgcatttgtt
     1921 tatatggatg acaatatgga aacttgggtt tctgatgtga aaaaatcatt gacatctaaa
     1981 aaagtgacca tcgtcaaggg aactggtaac atgctcttgg tagcaggagt tggacatgac
     2041 catcaccatg aggaagctga caaaaagcat gagcataata aacatagcga agaaggacac
     2101 aaccatgctt ttgacccaca cgtgtggttg tcaccatacc gtagcattac ggtcgttgaa
     2161 aatattcgcg acagtctttc aaaagcttac ccagaaaaag cagagaactt caaagccaat
     2221 gccgctactt atattgaaaa attaaaagag cttgacaaag actatacggc agcactttca
     2281 gatgctaagc aaaagagctt tgtgacacaa cacgcagctt ttggttatat ggcacttgac
     2341 tatggcttga accaaatttc tattaatggt gtcacaccag atgcagaacc atcagcaaaa
     2401 cgtattgcta ctttgtcaaa atacgttaaa aaatatggta tcaaatacat ttattttgag
     2461 gaaaatgcgt caagtaaagt cgcaaaaacc ctagctaaag aagcaggagt taaagcggct
     2521 gtgcttagtc cgcttgaagg tttgactgaa aaagagatga aagctggcca agattacttt
     2581 acggtcatgc gtaaaaacct tgaaacctta cgcttaacca ctgatgtggc tggtaaagaa
     2641 attcttccag aaaaagacac gactaagaca gtttacaatg gttatttcaa agacaaagaa
     2701 gtcaaagatc gtcaattatc tgactggtca ggtagctggc aatctgttta cccctatcta
     2761 caagatggta ctttagacca agtttgggac tataaggcta aaaaatctaa aggtaaaatg
     2821 acagcagccg agtacaaaga ttactacact actggttata aaactgacgt ggaacaaatc
     2881 aaaatcaatg gtaagaaaaa gaccatgacc tttgttcgta atggtgaaaa gaaaaccttc
     2941 acttacacat acgccggcaa agaaatcttg acctatccaa aaggaaatcg cggagttcgt
     3001 ttcatgtttg aagctaaaga accaaatgct ggcgaattca aatacgttca attcagtgac
     3061 catgccattg ctcctgaaaa agcagagcat ttccacctgt actggggtgg tgacagccaa
     3121 gaaaaattac ataaagagtt agaacattgg ccaacttact acggttcaga cttatctggt
     3181 cgtgaaattg cccaagaaat caatgctcat taatcttaac tcactaagca aatcttcttt
     3241 taaggaggtt tgctttttct ttgtggagta aaaaaattta ataattctca acattaattt
     3301 gacggacact tatgattata atatacttta agtggttata acaagttaga ggtgaataag
     3361 atgccaaaag aacaaccact ctatctacag attgttgatg acttggaagt gaaaatcaaa
     3421 aagagcatga cagaaaacga taagttgttg tcagaacgag aattaagtga cctttacggt
     3481 gttagtcgta tcacgattag actggctctt aaggaattgg aattacgaga cttaatttat
     3541 aaaaagcagg gcaaggggac ttatgtttca ggaatcaaag aacctgtcac tgatttatca
     3601 agtacttaca gctttacaga gcaaatgaaa aaagtgggga aaactcctaa aacagagatt
     3661 ctttcttttg aacagtatca ggtaacacct tacttgtctg gtctcttaga gtttgatctc
     3721 gatacagaag tttttgaatt agagcgccta aggattgcag atgatatgcc cttgatgttt
     3781 gaacgatcct atattcctgc gcagcctttt caggggttaa gcattgcgga cttgaagcgt
     3841 aaagctttgt acgatatctt tgcaaaggac tatcaagaga caatccgtct tgcagaagaa
     3901 gagttttatg ccagcattgc cttggactat gaagcagacc ttttgggaat caaaaaagga
     3961 gatcctgtct tacatattat tcgtaaaact tataacgata aaaatatttt gatcgaattt
     4021 actttcagta ttgcaagagc agaccagttt aggtataggg tacaacatca ccccaatggt
     4081 taaagaaatg ggaggttaat acatgtttac aaaaacgcag gaagctttgg aggctcttgg
     4141 tgcagctatc actaccaagg aaattaaaca agaaccccgt ttatggcaag aaaccatgac
     4201 gttttttgaa gaaacaagag attctctgga ttctttttta aagagagttt gtaaaagcgc
     4261 taatggaaat aacgttcatg tcatctttac aggtgcgggt acatctgagt acatcggtaa
     4321 taccatttgc ccttacttga agaaggtggg gaatcggcag tgctatctct ttgagagtgt
     4381 tgcttcaacc gatttggttg cggcgccaga ttattatctt gctgaggaag agacggtact
     4441 attagtctcc tttgctagga gtggtaatag tccagaaagt gtagcggctg ttaacctggt
     4501 caatcaacta gtgccaaata gttatcattt aaccattacg tgtgccaaag atggagaact
     4561 ggcgaaaaaa gcacagcaag atgagcgttc ttacctttat ttgatgcctg aagacgctaa
     4621 tgatgctggt tttgccatga ctggtagttt tacctgtatg atgctagcgg ctcttttgat
     4681 ttttgatgat gctaacagta tagctcagaa agaagcttat gtgactgata tgattcttgc
     4741 tgggcaagct gttattgacc aagaaagacg gctacaagag ctagctgatt taggatttga
     4801 acgtttagtt tatctaggtt ctgctggttt agccaagtta acccaagaag ctcaattaaa
     4861 aatgttagaa ttgacagctg gacaagttgc gaccctctac gagtcctcta tgggctttag
     4921 gcatggtccg aaatctttta ttaatgaccg taccttagtc attggatttg tcaataatga
     4981 tgcttacgtc agacagtacg atttggacat gttagaggaa atccaagcag atggcattgc
     5041 ccttaaaatc ttggctctat tgcaaggagg ggatatcaac ttttcagagg accaatttcg
     5101 actagacacc cgtcacttat tgccagaagc ttacttagct tttcccatga ttttagtcgc
     5161 gcagaccttg gccctcttaa cggccgttac attaggaaat tcccctgaca ccccatctgc
     5221 gacaggaacg gttaatcgtg tggtcaaagg agtaacgatt cacccttacc cgactagtag
     5281 tcgtcaatgc aacaaagctt aaagcttttg tgtagaagcc gtaaaacgaa atgattttgt
     5341 gctagtaggc caaaagaaaa accctcctga tacaggaagg ttttttgtat tgtcttgctt
     5401 attttgctgc gtttgcgtct ttgagaccgt attttttgtt gaagcggtcc acacgtccat
     5461 ctgcttgagt gaacttttga cgtcctgtgt agaatgggtg tgaatctgat gaaatttcca
     5521 cacggataag tgggtaagtt tcaccttcaa actcaacagt ttctttagaa gcttttgttg
     5581 agccgctaag gaactggtaa cctgtagttg tatcaaggaa aacaactgga cgataatctg
     5641 gatgaatgtc ttttctcatc ttaaaaaatt cctttctgcc atgacacttg atgcatcata
     5701 gttattaact attctagtgt aacaaaactt gaatgacttg acaaggcttt tctttcctta
     5761 ttttttaaaa atcctaaatc tcttggcaaa cagcgatgag ttctcggaaa atagcttgat
     5821 tttcttctaa attagctgag ttggctccgc tagcaagggg atgcccccct ccaccgtgac
     5881 gcttagcaat gccattaata atcttttctt tactgcgcat acgcacacgg tagttgccgt
     5941 cagttaactc aacaaaaata gcccaagctt gaacgttatc aattttacca ggagcacaga
     6001 caatggcaga gctttctgct agggtcacgt caaaatgttt taaggtttct tggctgacaa
     6061 ggacataagc agccccactc tcatcaattg ttaaatgctc aaagacgtag ctttgcagct
     6121 ttgctatttt caaaggaaac gaatccattt gccttgaaat cgcagcaaag tcgaactcga
     6181 aatgtctgag ttggctagca atggaaaggg ttttactagt ggttgaggca taaagaaatc
     6241 gccctgtatc accaacgata ccagtgtata agagcttagc agccttgtca gagagagtaa
     6301 gattctgact aaaggcaaag tctgcaatga tttcacttgc gctagaagcg cttgtgtcca
     6361 cataatagaa gtcaccatac acatcatcgt tgggatggtg atcaatctta attaagcact
     6421 gccccagtgt gtagcgctca tcatcaatcc ttggtcgatt cgctgtatct gtaatgatga
     6481 ccaaagcctc tttatagtct ttatcagtca cctgatccat ttggctaatc caagttaaac
     6541 taggctcatc aaaaccagtc atcaaaacct ttttatctgg gaaattttgt gcaataattt
     6601 ctttcaagcc ggcctgacta ccaagagcat cagggtcagg attttgatgg cgatggataa
     6661 taatagtttg gtgagctttt attttatcta aaattgtttc aaaagttgtt atcatgcttt
     6721 aatctttctt tttcaaaaag aggaaaataa ccgtttaaca tagtcttcaa aaaacggttt
     6781 gtgtcataag gaggtgtgcg ttatgttaag tggctaatgc tagaattttt taagattgtc
     6841 aaagctcata aattgacatt ttatctgaaa atcatatcct attttattat agcataaaag
     6901 taagctctag ataatggtaa attaatctag gaagaaaaga ggttagttat cagttatgat
     6961 actatcaaag ctagttttgc aaatgcaagt gaaaaaatag tttttaagtg tcttaagtaa
     7021 tcatatcaac tttctcttta aacaattagt gcttttccta aaaaagtgtg ctaaaataaa
     7081 catagtttag taattttggg aggaatttat ggcattagca aaaatcgttt atgccagcat
     7141 gacgggaaat actgaagaaa tcgctgatat cgttgcaaat aaattgcaag aattgggcca
     7201 tgatgttgac attgatgagt gcacaacagt tgacgcttca gagtttgaga atgctgatat
     7261 cgctgtcgtt gcgacttata cttatggtga cggtgactta ccagatgaaa tcgttgattt
     7321 ttacgaagat ttacaagatt tagatttaga aggtaaaatc tatggcgttg tcggctctgg
     7381 tgacactttt tatgactatt tttgcaaatc tgttgatgac ttttcagatc aatttgcgct
     7441 tactggtgcc gtcaaaggtg cagagccagt caaagtagat ttggcagcag aagatgaaga
     7501 catcgatcgt ttagaggcct ttgcagagca actctcacag gctgttaata atctataaaa
     7561 ctatttagta aaaatgtcag ggacttcctt ggcattttta gatttttaac ctaaaataaa
     7621 gggaatgtca cttcagggta ggaattgaaa aaacaatcag cttcaccttg cttctgatcc
     7681 tcttattaac tataataaaa agataatcta atacatctag aaaaggaaag ttatgcgttt
     7741 agaagagata cgacaagaaa tcaatggtat tgatcaccac ttggttgcct tattagaaaa
     7801 gcggatggca cttgtagagc aagtaacagc ttataaacta gccaatcact tgcctgtctt
     7861 agatcaggcg agggaaaatc agatcctaga tagggtttct tatctcgtta aagaccaagc
     7921 atttgagcca gctatccatg agacttttaa aaccattatg tctctttcac ggcagtatca
     7981 aacgcaacgc ttaacaggtg gtgacattaa tgattaaatc aattgcaaca ctgcctaaac
     8041 cctccttaaa agaagcgtta ggactaatag gcttggcgct tcccataggg gccacggttg
     8101 gagtggttga tgtgattttt ggtaaagggc ttttgtttct ttccgaatat cgcgatcacc
     8161 acctgttctt gcttcttcct tttcttgccc tagcaggtct tgttatcgtt tttctttacg
     8221 ataagttagg caaagaggtt cgtcaaggga tgggattggt ttttcaggta gggcatggtc
     8281 aaaaagatca gattcctcct attctcattc ctcttatttt gttctcgact tgggtaaccc
     8341 acttatttgg agcgagtgcg ggtcgagaag gggtagccgt tcaaatagga gctaccatct
     8401 ctcattattg tcagagattt gtgactagtc aagaagccgc acgacacctt ttgattatgg
     8461 ggatggcagc cggttttgca ggactttttc aaacgccgat tgctgctgtc gtatttgccc
     8521 ttgaggtttt gttggtagga acgcttcgct actgcgcttt attgccttcc ttagttgctg
     8581 cttgcgtggc ttcttggacc tctcattctt tgggattaga gaaatttacg attgttcttg
     8641 aagaaacatt gaccataact cccttaacat tggttaaatt aattgggtta ggccttattt
     8701 ttggtctggt gggaaatagt tttgcctatt tacttggctg gtttaaacct tacctcagtc
     8761 aaaagctacc aaatccttat ttccggattg cttttatcgg tgctttgtta tctatctgtc
     8821 tgatgattgg tcacgtcgga agatatagtg gtctaggaac tcatttgatt gcggcagctt
     8881 tttctggcca aactatccta acttacgact ggcttttaaa aatgatcgtg acggtgatta
     8941 gcttatctgc aggctttcaa ggtggtgaag tgacgcctct atttgctatt ggagcttctt
     9001 taggcatcgt tttggcccct tacttaggtc ttcctgtact gttggttgct gcacttggtt
     9061 acaccacggt atttggaagt gcaacaaata ccttttgggc ccctatcttt attgggatag
     9121 aggtctttgg tccagagaat gccctagcat attttgtcac ctcggctgca gcctatatgg
     9181 ttagtcacag acattccatt tacagttatc aaaaagtagt catgatcaat ttaaaagaca
     9241 tgacggtaaa tcagatggat ttaaaaaaat agctttacaa taaagaagct ttttgttaga
     9301 ataaatctcg tgtgtaatgg acacacgaaa attacggcta atccgctaag acaagtactt
     9361 aagattagta agataggaga ataaaaatga atccattaat ccaaagtttg acagaaggtc
     9421 aacttcgctc tgatatccct aacttccgtc ctggtgacac tgttcgcgtt cacgcaaaag
     9481 ttgtcgaagg aactcgcgaa cgtatccaga tctttgaagg tgttgttatt tcacgtaaag
     9541 gtcaagggat ctcagaaatg tacactgttc gtaaaatctc aggtggtatc ggggtagagc
     9601 gtacattccc aatccacaca ccacgtgttg acaaaatcga agttatccgc cacggtaaag
     9661 tccgtcgtgc gaaactttac tacttgcgtg cattacaagg taaagctgct cgtatcaaag
     9721 aaattcgtcg ttagtttgaa ccgaaacgta acgtaataga ataaaaagac tagagtctct
     9781 agtcttttta tgtcgtcgtg acaatgtgac aattggtgat taacgctatg ctcgtaggac
     9841 actttgaaag ttccttagca gttataatta gtatattgta ataacaaaat gaagcaaaat
     9901 aaactttcag ttatctgata tttcatcttg cattacctta ttttctaggt taaaatagaa
     9961 gacaaggtga atataagata ggccccttag ttcaatggat ataacaactc cctcctaagg
    10021 agtagttgct ggttcgattc cggcaggggt cattattgtc actgaaaaag cctttacatc
    10081 aaaggctttt tgttttattc cggttttaaa aggggcagtt tgtttattta taatttcttt
    10141 catgtttaca gttgtgtgac tgtaaataga taatgttgtt tttggatcgc tgtgaccaac
    10201 tctatccatt atcgcattta gcggtatccc tttttctgct aaaaatgata tatgcgagtg
    10261 tctaaataag tgcgtgtgat aatctccgta aattttcaat cgcttattga tgtgtgcatt
    10321 taaaattggt aaaccttttg aatatggaaa gctgttagca ctctgcttgt gattaatcta
    10381 tcgtatgtta aaagtgacat ttaaattaaa tcatttttta tacatatatt tcaacaggat
    10441 ttatcatatt ggaaaatagc ggtgcttcta ttggcatttt actattgaca ggaatttccc
    10501 tgtcttttgt ctcctaaaga agatcagctt tgatttctaa cttgattaga gtgggcttgg
    10561 tactgtttat gaattatcag tatatacttt ctggagatca aaaaggaaag gaacagctaa
    10621 agaggtgtat gtgttaccat tagaggaata gaacatcgca agactcgttt attcagtcat
    10681 tacgatacct gttttatttg ggaaataact ataatattaa gtgaatttgt gatataatga
    10741 aaggtatgaa ttatcaagat tatatatggg atttgggagg taccttactc gataattacg
    10801 agctttcaac ccaagctttt gtccaaacgc tagctttttt cagccttcca ggagatcacg
    10861 atgctgttta ccaaaaatta aaagaatcaa ccgctatcgc tgtggcaatg tttgctccta
    10921 atgagccaga atttttgcat gtgtataggc taagagaagc agacaaattg gcacaaccca
    10981 tttggtgttt gggagctaaa gaaattttgg aaaagatagc gacttcaggt tcgcgaaatt
    11041 ttttaatttc tcatcgagat tgtcaggtga accaactttt agagcaagct gggttgctaa
    11101 tctattttac agaagtcgtg acagcttcaa atggctttgc tcggaaacca aatcctgaaa
    11161 gtttgtttta tttaaaagaa aagtatgata ttaatagtgg attagtaatt ggagatcggc
    11221 taattgataa acaagcagga caagcagcgg gctttaatac cttgcttgtt gacggtagaa
    11281 aaaacctatt ggagatagta acgtagatga ttgaagaaaa taaacatttt gaaaaaaaaa
    11341 tgcaagaata cgatgccagt caaattcagg ttctagaagg gctggaggct gtccgcatgc
    11401 gtccagggat gtatattggc tcgacagcta aagagggttt gcatcattta gtctgggaaa
    11461 ttgttgacaa ctcaattgac gaagcattag caggttttgc ctctcatatt aaagtcttta
    11521 ttgaagcaga taattccatt acagtagtag atgatggccg tggaattcca gttgacatcc
    11581 aagccaagac aggacgtccc gccgtcgaaa cagtttttac agtcttacac gcaggtggta
    11641 aatttggcgg aggcggctat aaggtttctg gaggattaca tggtgtaggg tcatctgttg
    11701 ttaatgcttt atcaacacaa ttagatgtac gtgtttataa aaacggccaa attcattacc
    11761 aagaatttaa acgcggggct gttgtagcag atcttgaggt cattggaacc actgatgtga
    11821 ctggaacaac ggtacacttt acacccgatc cagaaatttt taccgaaacg actcagtttg
    11881 attacagtgt tttagcaaaa cgtattcaag agttagcctt tttaaaccat ggtttaaaaa
    11941 tttccattac agataagcgt tcaggtatgg aacaagaaga acatttccat tatgaaggtg
    12001 gaattggttc ttatgttgaa tttttaaatg ataaaaaaga tgttatcttt gaaacgccca
    12061 tctatacaga tggtgaatta gaaggtattg cagttgaagt agccatgcaa tatacgacta
    12121 gctatcaaga aacagtcatg agttttgcta ataatattca tactcatgaa ggtggaacgc
    12181 atgaacaagg ctttagagcg gctcttactc gggtcatcaa tgactacgct aagaaaaata
    12241 aaattcttaa agaaaatgag gacaatttga caggagaaga tgttcgtgaa ggtttgacgg
    12301 cggtaatttc tgttaagcat ccaaatcctc aatttgaagg tcaaaccaaa acaaaattgg
    12361 gcaactcaga agtggttaag atcactaatc gtctctttag tgaggccttt caacgttttc
    12421 ttttggaaaa cccacaagtt gctcgtaaga ttgtggaaaa agggattttg gcttctaaag
    12481 ctagaattgc agctaagcga gcccgcgaag tcacccgcaa aaaatcaggc ttagaaattt
    12541 caaacttacc tggaaaatta gcagactgtt cgtcaaatga tgctaaccaa aacgaacttt
    12601 tcatcgtcga aggagattca gcgggtgggt cggccaaatc aggtcgtaac cgagagtttc
    12661 aagctatctt gcctattcgc ggtaaaattt tgaacgtgga aaaagcaact atggataaga
    12721 ttcttgccaa cgaagaaatt agaagtctct ttaccgctat gggtacaggt tttggtgcag
    12781 actttgacgt gtcaaaagct cgctaccaaa agctggttat catgaccgat gccgatgtgg
    12841 atggcgctca tattagaacc ttgcttttaa ctttgattta ccgctttatg aggcctgttc
    12901 tagaagctgg ctatgtttac atcgcccagc cacctattta tggtgttaag gtcggtagtg
    12961 agattaaaga gtatattcag ccaggtattg atcaagaaga ccaattaaaa acagctcttg
    13021 aaaaatatag tattggtcgt tcaaaaccaa ctgttcaacg ttataaaggt cttggggaaa
    13081 tggatgacca tcaactttgg gaaactacta tggatcctga aaatcgtttg atggcgcgtg
    13141 tgacagttga tgatgccgca gaagcagata aagtatttga tatgttaatg ggagatcgtg
    13201 ttgaaccaag acgtgatttc attgaggaaa atgcggttta tagtacactg gatatttagt
    13261 caccttttta gtttcacaag gaatctgcta ccaaagagga cgaattgact aaaaatcatg
    13321 atgcatgatg ccaacagctt tgttagttag tacgtcttca tctttgttag ttagtacgtc
    13381 ttcatcttga gggacagcgt taatgcatag gtattgagac cgccccttaa tacctatgtt
    13441 agtccttatt aagaaagcct tgtgagtcgc tggtacgaga ttgttgaatt agtcaaatat
    13501 attttgaaat gcattttaaa gtatgttata atcgtaatgt tatagtgtat tttaaataaa
    13561 attttaataa aaggcgattg aggaatttca gtttttagtt attactggaa caatgttgat
    13621 aaatcgtgtc taaataataa ggagattcag atgtcaagcg gaattatctt gctgattgtg
    13681 gctatagtcc tactagtgat tatcgcctat ctagtgggtg tcatcatacg aaagcgtaat
    13741 gattccctaa ttaccagtct agaagaacga aaacaggcct tgtttgcttt gcctgttaat
    13801 gatgaaattg aagaagtaaa gtcacttcat ttgataggac agagccaaac ctcttttcgg
    13861 gaatggaatc agaaatgggt agacttaact gtaaattcgt ttgcagatat tgaaaatcat
    13921 atttttgaag ctgaaaattt gaatgatacg tttaatttta ttcgcgccaa gcatgagatt
    13981 aatagcgttg aaagtcagct taatcttgtt gaagaagata tcgcttctat tcgtgaggca
    14041 cttaatatct taaaagagca agaagaaaaa aatagtgctc gtgtcaccca tgctcttgat
    14101 ttatatgaaa agctccaagc ttctatttct gagaatgaag ataattttgg ttcaactatg
    14161 cctgaaattg acaaacagat gaaaaacatt gaaactgaat tttcacagtt tgtcgcactc
    14221 aactcatcag gtgatcctgt agaagcttct gaagttctgg atagagcaga agagcatact
    14281 attgctctag ggcagattac agagcagatt ccagctattg tcgccaagtt ggaagatgat
    14341 tttccagatc agttagatga tttggaaaca ggatatcgcc gtttacttga agaaaactat
    14401 cattttccag aaaaaaacat tgaggcacgt tttcaggaga ttcgtgagtc tattcgtgcc
    14461 aattcatcag agttagttac acttgacttg gatcgtgcta gagaagaaaa cacgcatatt
    14521 caagaacgca ttgattctct ttatgaagtc tttgagcgcg aaattgccgc ttataaggta
    14581 gctgctaaaa atagtaagat gctacctcgt tacctagcac atgtgaaacg taataatgaa
    14641 caactcaaag atgaaattgc acgtttatca cgtaaatata ttctaagtga aacggaaagt
    14701 ctgactgtta aggcatttga gaaggatatt aaagagatcg aagacagtac acttgctgtt
    14761 gcagaacaat ttggtttaca agaaaaacca ttttcagaac tgcaagtgac ttttgaacgc
    14821 agtataaaga cgcttactaa tgtcgagtca ggtcaaatgg atgtttttgc agcagttaaa
    14881 gatattgaaa aaattgaatc acaggcacgc cataaccttg atgtttatgt tactcagctt
    14941 catatgatta aacgttatat ggaaaaacgt cacttgcctg gaattccaca agactttctt
    15001 agtgctttct ttacaacgag ttcacagttg gaagctttga tggatgagct tagtagagga
    15061 cggatcaata ttgaggcagt gtcacgtttg tcggaagttg cgacggttgc tattgctaat
    15121 ctagaagatt taacctatca agtggttcaa aatgctacct tgactgaaca attactacaa
    15181 tattctaatc gctatcgttc ttttgaagca ggagttcaaa gtagttttga acatgctttg
    15241 agacttttcg aagtagaaaa tgattatcag gcttcttttg atgaaatttc ttatgctctt
    15301 gaaacagttg aacctggggt aacagatcgg tttgttaact cttatgaaaa aacacgagag
    15361 cacattcgtt tttgatactt gaaagtcgtg atattctcac gactttttat tagctttttg
    15421 gaccaatacg tgtttttgac tagaatcttc tttttaatga tcaaaagaag aagtagtaac
    15481 agtgtttttt gctattgaga ggatagttat tttttcaaaa atcttttcca aaaggatttg
    15541 gttttttcag gagtttgttt gctaagttga tcgttttttg tctgctttaa gatgacttct
    15601 aaacgcgttt cctttagatt tattgcgtgg tcggtatgaa ggataaacgc aaaaggtgaa
    15661 gtcatatgcg tttctgtaat aatagtaaca ggtaaatggt tttcttttgc taatttcata
    15721 tagagtattt gaagttgagg tgccagcttg gaagagattt ttaagtgtaa aggttgatag
    15781 actaactgaa ggctcggtaa ttctcttttc aaatagtctt ttactgtttt agtttgagct
    15841 tcgtctaata aagcacttaa aacgactcgt tcagcatacg ttcccagata gtagcgttgc
    15901 tgctcaggat ttaatcttct ttctccccag gctcctttta atagcttatc ttctaaatta
    15961 gtcatagata ccctcgcttc tttataata
//
LOCUS       DAUGUF010000037        15683 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUGUF010000037 DAUGUF010000000
VERSION     DAUGUF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15683
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.037"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            24..749
                     /locus_tag="VIB71_001422"
     CDS             24..749
                     /locus_tag="VIB71_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823151.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            752..1786
                     /locus_tag="VIB71_001423"
     CDS             752..1786
                     /locus_tag="VIB71_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823152.1"
                     /translation="MKALFLKRRQNFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNVLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            1850..2641
                     /locus_tag="VIB71_001424"
     CDS             1850..2641
                     /locus_tag="VIB71_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEQ8823153.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            2641..3276
                     /gene="trmB"
                     /locus_tag="VIB71_001425"
     CDS             2641..3276
                     /gene="trmB"
                     /locus_tag="VIB71_001425"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEQ8823154.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            3341..3427
                     /locus_tag="VIB71_001426"
     tRNA            3341..3427
                     /locus_tag="VIB71_001426"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3375..3377,aa:Ser,seq:gga)
     gene            complement(3474..4553)
                     /locus_tag="VIB71_001427"
     CDS             complement(3474..4553)
                     /locus_tag="VIB71_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ8823155.1"
                     /translation="MAFYRKLGSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AEIDLNTLTADLLDITVLDYNRRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGAKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADGAIVRSQKP
                     AKEESEKFMEESEYLAFIKVAKSKVKYPSYLTTYIIAVTGLRFAEVQGLTWKDIDFEN
                     GYIDINKTFDYSISQNFGPTKNEQSIRKVPIDKNSLEILRNFKSDYYQDNKLGRVCFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKFDG"
     gene            complement(4670..5221)
                     /locus_tag="VIB71_001428"
     CDS             complement(4670..5221)
                     /locus_tag="VIB71_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823156.1"
                     /translation="MDIAKLKEFAITAAGKAKDGAIKANELRKKASQESKIILPPALN
                     LELGAQTAIRKTIDGKYYIGFYSETPELYEFVSLQFDGSRIIEKTVTKGKTTQKGRSS
                     SVLGGAAIGKVLAPGVGTIIGGMAGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEVKTLKTKLTQAQYVSVNNFFK"
     gene            complement(5232..5615)
                     /locus_tag="VIB71_001429"
     CDS             complement(5232..5615)
                     /locus_tag="VIB71_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEQ8823157.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMIKEELEFLIS"
     gene            complement(5629..6030)
                     /locus_tag="VIB71_001430"
     CDS             complement(5629..6030)
                     /locus_tag="VIB71_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8823158.1"
                     /translation="MLFYRYFLSSHRKADKSMFSTFERIKELAKSRGISLGLLEEKLG
                     LSRNSIYTIKNKKPSAERLQLIADYFHVSTDYLLGRTDNPKIAQDGHASVAIDLKKDA
                     EETFFFDGHELNDEDIDLITSILETRIKNRK"
     gene            6305..6457
                     /locus_tag="VIB71_001431"
     CDS             6305..6457
                     /locus_tag="VIB71_001431"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823159.1"
                     /translation="MDEKNPLEQFEEFCKNNSFEYVKGWVDGMQSVLNILSMELSKKK
                     WIYFGG"
     gene            complement(6442..6855)
                     /locus_tag="VIB71_001432"
     CDS             complement(6442..6855)
                     /locus_tag="VIB71_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823160.1"
                     /translation="MEKYNFWLTIATAVLPAAISAIISFLASRYKNRSDIESLEKKFN
                     HEMTTIEKNHSNDLERLEKQYQHDFEAMEKNHFRELEKMKEAHTLELENIQKQSEAEV
                     NNTVAQGLMTMLGSAMTPALSKYLEENDVFNQPPK"
     gene            6903..7118
                     /locus_tag="VIB71_001433"
     CDS             6903..7118
                     /locus_tag="VIB71_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8823161.1"
                     /translation="MSQQHKKWSALVEQRLKEKGWTRVDLALAAGLRSSGTITDLLTK
                     GKGSVDLKVRVSKILSIREPWELFENE"
     gene            7180..7455
                     /locus_tag="VIB71_001434"
     CDS             7180..7455
                     /locus_tag="VIB71_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEQ8823162.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVMKMINNETEIYPLELNKKQVS
                     KMFGVDPKTFDARFNSHKDFPRIETGGREKYPRDLAIEWYHRNWSIT"
     gene            7452..7622
                     /locus_tag="VIB71_001435"
     CDS             7452..7622
                     /locus_tag="VIB71_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823163.1"
                     /translation="MNKLELFLLATTVILAVIARVQHEVIKKHNSPENKRRIFREVAL
                     ENSKKWSAERYV"
     gene            7615..7818
                     /locus_tag="VIB71_001436"
     CDS             7615..7818
                     /locus_tag="VIB71_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823164.1"
                     /translation="MSKWELQKQLLANATDFESTVEALFELNELGEISDEELLLNLRS
                     SYRKYSEEKLCIIDKLIKLGGAE"
     gene            7815..8201
                     /locus_tag="VIB71_001437"
     CDS             7815..8201
                     /locus_tag="VIB71_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823165.1"
                     /translation="MMTTFEKIIKNLNRIERELVKPEAERRDSLPILSAQLSAIKQDL
                     KLMLWIELPALNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            8347..8550
                     /locus_tag="VIB71_001438"
     CDS             8347..8550
                     /locus_tag="VIB71_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823166.1"
                     /translation="MNYLEYALAYLERELEIIDDEVIEVELPGGDWEFVPNPYYEEGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            8638..8937
                     /locus_tag="VIB71_001439"
     CDS             8638..8937
                     /locus_tag="VIB71_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823167.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            8937..10091
                     /locus_tag="VIB71_001440"
     CDS             8937..10091
                     /locus_tag="VIB71_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEQ8823168.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYED
                     AEIELEKRIDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYDSYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVLTNKEAAATILEKNGFEDIYKPKELLSM
                     GALEKMVGKKRFEDMMAFILDKPQGKPVLVKNSDKRPALNSLEQAIKEFE"
     gene            10095..10493
                     /locus_tag="VIB71_001441"
     CDS             10095..10493
                     /locus_tag="VIB71_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823169.1"
                     /translation="MKIYKVKVKFRQTCHKKFKGKKYSYFSFEELRVGDLVVVETVYG
                     PSVAKVTEVVDANELFTATSYVISKVDTSLLAGKKELMATALTVKANIDAETAEFAAK
                     YKDAYYLGLFDQYKNQNPELAELLTQLKEL"
     gene            10504..11061
                     /locus_tag="VIB71_001442"
     CDS             10504..11061
                     /locus_tag="VIB71_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEQ8823170.1"
                     /translation="MTPSTTKVVTGKVRLSYAALLEPKAFEGQEAKYSTVILIPKTDK
                     VTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHMFMSVS
                     SKTRPQIIDRYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAKGD
                     YLGGRSSADADFDEWNEEEDEDDIL"
     gene            11104..13026
                     /locus_tag="VIB71_001443"
     CDS             11104..13026
                     /locus_tag="VIB71_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEQ8823171.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPAQWQCTMVLA
                     QELGLPASLEKCALYLKLAQEKDAAGKNLIKYFSVPCKPTKANGGRTRNLPEHDPGKW
                     QMFINYCMQDVVVEMAIAEKLESVPVHDREWDYYVCDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKALTGLDNPNSRAQLLPWLKEHGYSANGLTKADVEQELKKAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGYTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKI
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDRAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYDVVFHVHDEAIIEGSGLIIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            13031..15415
                     /locus_tag="VIB71_001444"
     CDS             13031..15415
                     /locus_tag="VIB71_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ8823172.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAFVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLSEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVSDLPEIKDHLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNNFKTKFDPELHARSSHPVVYDPEATCETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGAALKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELNYENKNVKSDGKQAKNWVGFRLKSEF"
BASE COUNT         4877 a         2770 c         3393 g         4643 t
ORIGIN      
        1 atcaaaaact agaaagaaat tatatgttaa acattaaaaa tctaacagga ggatatcaca
       61 atatccctgt tttaaacgat gtctcatttt ctgtagacaa tggagagtta gtcggtttga
      121 tcgggctaaa tggtgctgga aagtcaacaa ctatcaacga aattattggc tttttgaagc
      181 cttatcaagg aagtatttct attgatggtt taactctagc agaaaatgca gttgcctacc
      241 gtcaaaaaat aggttttatc ccagaaactc ctagtctcta tgaagaattg accttatcag
      301 agcatatcaa caccgtagct atggcttatg atatcgactt agaagtggca caaaaacgag
      361 cacaaccttt cttggaaatg tttcgtttaa ctgacaaact tgaatggttt cctgtcaatt
      421 tttctaaagg gatgaaacaa aaagtcatga ttatttgtgc ctttgtcatt gatccaagtc
      481 tatttattct tgatgaacca ttcttagggt tagacccttt agctatttca gacttaatcc
      541 aaacgctaga agtcgaaaaa gcaaaaggaa aatctatttt gatgagtaca catgttttgg
      601 actctgctga aagaatgtgt gatcgttttg tgattttgca tcatggacaa gttcgtgccc
      661 aaggaactct tgctgacttg caagaagctt ttggtgaccg ttcagcgagc ttaaatgata
      721 tctatcttgc attaacaaaa gaggattaag tatgaaagca ttatttctga aacgccgtca
      781 aaactttcaa aaacaacaaa acaaatacct tcgttacgtc ttaaatgatc actttgtttt
      841 ggtgttgatg tttttattag gctttgctat ggtgcagtat ggtcagctac taaaccattt
      901 tccaacgaat catctaccta ttcaggtttg tcttgggata ttgatcccat tattgctcag
      961 tatgggatct atagcaacgt atctagaaga ggcagatcag catttcttac ttccaaaaga
     1021 agaagaagtg atttcttata tcaaacaagc tgagcgactc tcttttttgc tttggggaac
     1081 tttgcagact gctgtattgc tctttttata tcctattttt agacgtctag gtttgtcttt
     1141 atttattttt attatcttag ttttgatatt attggcacta aaaagagtag tgcttagtcg
     1201 aaagacaaga tattttttga gaggaaatcg tttagattgg gcaaaagctg tcgcatttga
     1261 aagcaatcgc aagcaaagta ttttaaagtt ttattctctt tttacaacag tcaaaggaat
     1321 ttctacaaaa gtgaaagaaa gaacttatct aaatcctctt ttaaaattag ttaagcaaac
     1381 tccttcaaac ctttggctgt ccctttatgc tagagccttt ttacgtagtt cagattattt
     1441 gggcttattt ttacgactaa tgctattaag ctcattatct gtatttttta ttcataatct
     1501 ttatttgtca gtaagtttag cactcatttt taactattta gttgtattcc aattactttc
     1561 actttattat cactacgatt accattatat gactagtctt tatcctgaaa atagtcggag
     1621 caagaagaaa aatgtgttaa gttttttacg aggtttaagc tttttaatgt taatcgtcaa
     1681 tatgctgtgt tgctcatcag cgccaaaagc actcattttg attgtaggta tggttttcat
     1741 agcttgtata tatctacctt ataagttaaa gaagatcatt gactaagtag cctaaaacaa
     1801 gtaaaatagg ggtaaacgac tataaaagat agaaaaggag ggcgataagg tgacaacgac
     1861 ggaacaagaa cttaccttga ctcccttacg tgggaaaagt ggcaaagctt ataaaggcac
     1921 ttatccaaat ggggaatgtg tctttataaa attaaatacg acccctattc tacctgcctt
     1981 agcaaaagaa cagattgcgc cacagttact ttgggccaaa cgcatgggca atggtgatat
     2041 gatgagtgcc caagaatggc ttaacggccg tacattgacc aaagaagata tgaacagtaa
     2101 gcaaatcatt catattctat tgcgccttca caaatctaaa aaattagtca atcaactgct
     2161 tcagctcaat tataagattg aaaacccata cgatttattg gttgattttg agcaaaatgc
     2221 acccttgcaa attcagcaaa attcatattt acaagctatc gttaaagaat taaaacggag
     2281 cttaccagag ttcaaatcag aagtagcaac gattgtgcat ggagatatta aacatagcaa
     2341 ttgggtgatt actactagtg gtatgatttt tttagtagat tgggattctg ttcgtctgac
     2401 tgatcggatg tatgatgttg cttacctgtt gagccactat attccacggt ctcgttggtc
     2461 agaatggctg tcttattatg gctataaaaa taatgacaag gttatgcaaa aaattatttg
     2521 gtatggtcaa ttttctcacc tgacacaaat tctcaagtgt tttgacaagc gtgacatgga
     2581 gcatgtgaat caggagattt atgccctcag aaaatttaga gaaatattta gaaagaaata
     2641 atgcgagtta gaaaacgaaa aggtgctgag gagcacttag ctaataaccc acactatgtg
     2701 atattaaatc cagaagatgc caagggccgt tggcatgacg tttttggaaa tgaccgtcct
     2761 attcatatcg aagttggttc aggaaagggc ggatttatca cagggatggc cttgaaaaat
     2821 cctgatatta actacattgg cattgatatt caattatctg tcctaagcta cgccttggat
     2881 aaggtattag cttcagaagt acccaatgtc aaacttctgc gagtggatgg atcaagttta
     2941 accaactatt ttgaagatgg tgaggtggat atgatgtatc tcaacttttc agatccttgg
     3001 ccaaaaacca agcatgaaaa acgtcgtttg acttacaagg atttcttaga cacttacaag
     3061 cgtatcttgc cagaacacgg tgaaattcat tttaaaaccg ataatcgggg cttgtttgag
     3121 tacagtttag ctagtttttc tcaatatggc atgaccttga gacagatctg gcttgactta
     3181 cacgctagta actatgaagg aaatgtcatg acagaatatg aagagaagtt ctctaataaa
     3241 ggtcaagtca tttaccgagt tgaggcaaat ttctagtagt attttgtttc aaaatatgat
     3301 aacataaagg agttgataca gtattaactt ctttagtaat ggagaggtcg catagtggct
     3361 tagtgcgcac gcttggaaag cgtgtagtcc ttaacggggc tcgggggttc gaatcccctc
     3421 ctctcctttt atcctcttga tatatcaagg gtttcggggt cttcgcccgt ctttcacccg
     3481 tcaaatttga gattttgaaa aatgtttttg acctgatggt catttttttc ttttaaactt
     3541 tctatctgat gagcgtaaac tttgagtgtg atgttgagat tttcgtgccc caacagcttg
     3601 gatactgata ttaaatcaac gccctgcgct atcaaataag aagcgtaagt atgccttagc
     3661 gagtgattgg ttagatttct gccagtcact ctttttataa ctttgttcgt tgcattattt
     3721 gacgctccaa agcatacacg accgagttta ttatcctgat aatagtcgct cttaaaattt
     3781 cttagtatct caaggctatt tttatcaatc ggtaccttcc tgatggactg ctcgtttttg
     3841 gtcggaccga aattttgaga aattgaataa tcaaaagttt tattaatatc gatatagcca
     3901 ttctcaaaat caatgtcttt ccaagtcaac ccttgaacct ctgcaaatcg taaaccggtg
     3961 acggctatga tatacgttgt caggtatgat gggtacttga ctttgctttt ggcaaccttg
     4021 ataaaggcga ggtattctga ttcttccatg aatttctctg actcttcttt agcgggtttt
     4081 tgcgatctaa caatggcccc atcggcaaaa ttatccctaa taatgccatc acgaatggcc
     4141 attttacaag cacccttgat ttgataatga aatttatcca gagtttgttg ggctactttt
     4201 gcgccaaagt cattaaggac ttgctgataa aaggtgtgtg tgatactctt gagcttccga
     4261 gtcccaaaat aatgttcgat gtgcttaaaa tttttggtgt atgtctgcca tgtctttgcg
     4321 gtaatgtgag gccttttata tatgtctgcc caacgtctgt tgtagtctaa aacagtaata
     4381 tctaaaaggt ctgcggtcag cgtatttaaa tcaatttctg cttgctgagc agcgactttt
     4441 gcaagtgttt ttgttttaaa tccacgtttt gatttttctc tttttttacc ttgactgtca
     4501 cgataggtga tgcgatactc ccacccagaa cctaattttc gataaaatgc cattgttttc
     4561 acctcatttt tctgttaaaa tgggtacaag aaaacgacct ttttaatggt tgtttcttat
     4621 acggttttgc ctcacgctct cctcgccaaa tttgagcgtg gggttttttt tatttaaaga
     4681 aattattaac acttacatac tgagcctgcg taagcttagt ttttaaggtt ttaacttctc
     4741 cggtttgtat atttcttaag gctaccgttg cttttccagg tatttcttca gaagtggttg
     4801 tggcagtagt gttaatggtt ccttttttct ttctagcccc accagccatt ccgccgataa
     4861 tggttccaac gcctggtgcc aaaactttac ctattgctgc ccctcctaga acactactag
     4921 aacgcccttt ttgagtagtt ttcccttttg ttactgtttt ttcaataatt cgtgacccat
     4981 caaattgaag gctaacaaac tcataaagct caggagtttc agaataaaaa ccgatataat
     5041 attttccatc tatggttttt cgtatagccg tttgtgctcc tagttctaaa tttagggcag
     5101 ggggtaggat tattttgctc tcttgtgagg ctttttttct tagttcgtta gctttaattg
     5161 caccgtcttt agctttccct gcagctgtta tggcaaattc ttttaactta gctatatcca
     5221 tgcttgtctc cttaactaat taaaaactct aattcttctt tgatcatcac ttcgtcagcg
     5281 attgaggtca gttcatactt ttccatgaat tggatgtagt tgaaatcctc catattatcc
     5341 caataggata gctcttcttt taagagatgg tgtatcatac atctatctgc ttgtagctct
     5401 gctttttctt tgtttagttt gtaataactc gcagtatgtt ctctatgtcc tagttcatga
     5461 tagatgactt tgtgtttata tataccgtca agataggtgt caatcgcaat gacgttgtgt
     5521 tttttattaa acattccagg ggtgtttgta cccctaccgt caaagtacac taaatcgatt
     5581 cctttttcct gacagactgt ttctggtgtc atcatagagc agtcctctct attttctatt
     5641 tttgatgcgc gtttccaata tagatgtgat aaggtctata tcctcgtcgt tgagttcgtg
     5701 accgtcgaag aagaaagtct cttctgcatc tttttttaga tcaattgcga ccgaagcgtg
     5761 cccatcttgc gcaatcttag gattatcagt tcgacctaat aggtaatcgg ttgatacgtg
     5821 aaagtagtca gcgattagtt gtagtctttc tgctgaaggc tttttatttt taattgtata
     5881 gattgaattt ctactcaatc ccaatttttc ctcaagcaat cccaaggaaa tacctcttga
     5941 ttttgcaagt tctttaattc tttcgaatgt tgaaaacatt gatttgtcag cctttctatg
     6001 agatgacaaa aaatatctat aaaaaagcat gtaaactact tgactgatta caaactttag
     6061 tctagaatat aatttgtaaa gcgaatataa aagcgaaaca aaaaacgaaa attaaaacta
     6121 aaaaaatata actttggcga gtttataagt agtttaataa tgtttttgtt ggtgttttta
     6181 ctataccttg attttagaat atagtttgta aaatgtcaat actaaagttg aaaaacttcg
     6241 cgattatttt cgctttactt ttaataaaaa aactcccgat tgggagtaga aaggagagag
     6301 tagtatggat gaaaaaaatc cactcgaaca gtttgaagag ttttgcaaga ataattcatt
     6361 tgagtatgtt aaaggctggg ttgatggcat gcaatcagtt ttaaatattc tctcaatgga
     6421 attatctaaa aaaaaatgga tctacttcgg aggttgattg aatacatcgt tttcttctaa
     6481 atatttagag agcgctggtg tcattgctga gcctaacatg gtcattagtc cttgagcaac
     6541 agtattgttt acttctgctt ctgactgctt ttgaatattt tctaactcta aagtgtgagc
     6601 ttctttcatt ttctcaagtt ctcgaaaatg atttttttcc atagcttcaa aatcatgttg
     6661 atactgtttt tcaagccttt ctaggtcatt actatgattt ttttcgatag tagtcatctc
     6721 atgattgaac tttttttcta acgattcaat atcagatctg ttcttatatc ttgaagctaa
     6781 gaagctaata atagcagaaa ttgcagctgg caaaacagct gttgcaatag ttaaccagaa
     6841 attatatttt tccataataa acctcaacat ttttatttat attatatcag aaaggagagc
     6901 agatgagtca acaacacaaa aaatggtcag ctctagttga acagcgatta aaagaaaaag
     6961 gttggacaag agtcgacttg gcacttgcgg ctggtttgcg gagttcagga acgattactg
     7021 acttacttac taaaggaaaa ggaagcgttg accttaaggt tagggtttca aaaattctta
     7081 gtatccgtga gccgtgggag ttgttcgaaa atgaatagta cacaaaaaag ccactgctgg
     7141 aacagtgact tagctaaaac atattaaagg aattttatca tggatagcag attattacaa
     7201 atgctagatg agtttgaagc gggccttatt gatcgcaaaa tcaaagtcat gaaaatgatt
     7261 aacaatgaga cggaaattta tccgctagaa ctcaataaaa agcaagtcag taagatgttt
     7321 ggggttgacc ctaaaacatt tgacgcaaga tttaacagcc acaaagattt cccgcgtatt
     7381 gaaacggggg gtcgggaaaa atacccacga gatttagcca tcgagtggta tcacagaaat
     7441 tggagtataa catgaacaaa ttagaactat ttttattagc aacaaccgtc atcttagcgg
     7501 tcattgctag ggtgcaacac gaagtcatca aaaaacacaa ttcgccagag aataaacgca
     7561 gaatttttag ggaagtggct ttagaaaaca gcaagaaatg gagtgcagaa cgttatgtct
     7621 aaatgggaat tacaaaagca actgttggct aatgcgacag attttgagag tacagtagaa
     7681 gctctgtttg agttaaatga attgggtgaa atctcggacg aggagctctt gttaaatttg
     7741 agaagtagct acaggaaata ctcagaggaa aaactttgta ttattgacaa actcattaag
     7801 cttggaggcg cagaatgatg acaacttttg aaaagattat caagaacctt aatcggattg
     7861 agagggaatt agttaagccc gaagctgaaa gacgagatag cttacctatc ctatctgctc
     7921 agttgagtgc tatcaagcaa gatttaaaat tgatgctttg gattgaactt ccggcgttaa
     7981 ataacgtaga aaaatatgaa gctctttatc aaggaaatga ttttaaattc agtgaaactt
     8041 tcttagagcg tcaagcgacg agaaaagcct tttggagacg attagctaaa gaaactttca
     8101 aagaagacca ggataagagg aactttgtta agttggctga gaaagaattt aaaggtgcaa
     8161 ctttgtcatg gcaagaattt ttgtggggta aaaagaaatg aacatatcac taaaatttat
     8221 tgatgaaacc ctagctggtt taaatgatat tttacgccag ggggggctct cttgttccca
     8281 aagccaagcc ctggcggacg cagtttttat attaacagct ttaaaacaag taattgagga
     8341 gagaaaatga actatttaga atatgcacta gcttatcttg aacgtgagct agaaattatt
     8401 gacgacgaag ttatcgaagt tgagttgccg ggcggagatt gggagtttgt gcctaacccc
     8461 tactacgagg aaggtttaca tgatagccca cactatcgta gtcaggttgc taaagacatt
     8521 cttgatatta aaggactttt ggggaggtga ggctattgat tgcatcaaaa aagacggctt
     8581 aggaaaccgt caacaattat acacaattaa attataacac agaaagagag aaacacaatg
     8641 attgaagtaa cttttaaagc agagagcatg gcaggtgttt tcgatgctat gcgtgaagct
     8701 ctggatatgc cgaagacagt aaccaaggat gttgttgaag aaaaaccagc tcctaaaaag
     8761 aaagaagagt ctgtaacttt gacattagct gatattaaga aaatggctaa agccaaggtt
     8821 gaagaaggga agtcaaagga catcaaggaa gtcttgaaag agatgaacgt cgcaaaagtt
     8881 ggtgaacttg aagaatacca gtttgctgag tttgttgaga agttggaggc cctctaatgc
     8941 cagtagaaaa tcacgcacta ctgtctgctt ctagtgctca cagatggctt tattgcccta
     9001 tgctgccgag attagaagca gactacccta gccgcgatac cgtatacact caagagggca
     9061 caagcgccca tgagctttct gaaatcaaac tgatgtacaa gtctggtaaa atcaccaagc
     9121 gtaaatttaa cacgttaacc aaggctttta aggaaaactc agacttctac aacgaagaga
     9181 tggaagagat gacggaactt tacacagata ttgttatgga gcacctaaat gcttatgagg
     9241 atgccgaaat tgaacttgaa aaacggattg attttagcga ctgggtgcct ggcggttttg
     9301 ggacttcgga tgtcgtcatt ttggcggatg gggtcattga aattattgat cttaagtatg
     9361 gcaagggtat gcctgtgtct gctaaccaaa acccgcagat ggggttgtac gctctgggag
     9421 cttacgattc ctacgatatg gtttatgact ttgaccgtat caagatgaca attattcagc
     9481 cgcgtttaga ttcggttagt tctgttgaca tttacgtaga ggagcttctg tattgggcgg
     9541 ataatgttgt cttgcctatg gccgctcaag cagacgcagg tattggcgac tggaacctaa
     9601 gtgaaaaagt attgcagtgg tctcctgtcg cagctaaatt ggtgccaaga gcgcaagaaa
     9661 actgggaatt aattgataaa tatgactatc aggagcctgt ctatttatct gatgaagccg
     9721 tcgcagagat ccttgacaaa gcctcagcta tcaagaagtg ggttgagtca gttgaagcct
     9781 atgccctgaa agaagcactc tcaggaaaag aagttccagg ctataagatt gtcgaaggta
     9841 gaagtaatcg tgtgcttact aataaggagg cagctgcgac aatacttgag aaaaacggct
     9901 ttgaagatat ctacaaacca aaagagctac tgtccatggg ggctctagag aagatggtcg
     9961 gtaagaagcg ttttgaggac atgatggcct ttatccttga taaaccacaa ggtaaacctg
    10021 tccttgtcaa aaatagcgac aagcgacccg cgttaaatag cttagaacaa gcaataaagg
    10081 agtttgaata gaatatgaag atttataaag taaaagttaa gtttagacaa acatgccata
    10141 aaaaattcaa gggtaagaaa tacagctact ttagttttga agagttgcgg gtaggtgacc
    10201 ttgtggttgt cgaaactgtt tatggcccta gcgtagccaa ggtaacagaa gttgttgatg
    10261 ccaatgagct ttttacagct accagctatg ttatttccaa agtggatact tcacttttag
    10321 cgggcaagaa agagttaatg gctaccgcct tgactgtaaa agcaaatatt gatgcggaaa
    10381 cggctgagtt tgcagcgaaa tataaagatg cttattattt aggcctgttt gatcagtaca
    10441 aaaaccaaaa tccagaatta gcagagttat taacacaatt aaaagaatta taggagaaga
    10501 attatgacac caagcacaac taaagtagta accggaaaag tacgcctaag ctatgcagct
    10561 ttactagagc ctaaagcctt tgaaggtcaa gaggctaagt attcaacagt tatcttaatt
    10621 ccaaaaacag acaaagtcac aatcaagaaa attaaagacg cgcagaaagc tgcttatgaa
    10681 gctgccaagg acaataaact caaaggggtt aaatgggagc gcgttaagac aacgcttcgt
    10741 gacggtgacg aagagatgga tactgaagag cacccagagt acgctggaca catgttcatg
    10801 tcagtgtcaa gcaaaactag gccgcagatt atcgaccgtt acaaaaaccc cgttgactcc
    10861 gcagacgaag tttactcagg agtatacgca cgagtatcat taaatgccta tgcctacaat
    10921 actgcgggta acaagggtat ctcttgtggt ctgaataacg ttcagattgt tgctaaagga
    10981 gactaccttg gcggtcgttc gtcagctgat gcagactttg acgagtggaa cgaagaagag
    11041 gacgaagacg acattttata gtagagggcc tctttagagg ctcctcattt ttaaaggaga
    11101 ggtatgagac atttaaatat tgatattgaa acctatagtt cgaatgacat caaaaatggg
    11161 gtttacaagt acgctgacgc tgaagatttt gagattttac ttttcgctta ctctatagat
    11221 ggcggagaag tagagtgcct tgatttgaca aggcagtctc tacctgaaga catcaaagat
    11281 atgttatttg atgataaagt ccgaaagcac gcctttaatg cccaattcga aagagtttgt
    11341 ctcagtcgtt acctcggcct accttactat ttagatcccg cacaatggca gtgtacgatg
    11401 gtacttgcac aagagctggg tctgcctgca agcctggaaa aatgtgcgct gtatttaaaa
    11461 ttagcgcaag aaaaagacgc agcaggtaaa aatctcatta aatatttttc ggtaccctgc
    11521 aagcctacaa aagccaacgg gggaagaacg aggaacctgc ccgagcatga tcctggaaaa
    11581 tggcaaatgt ttattaacta ctgtatgcaa gacgttgttg ttgagatggc aattgccgaa
    11641 aaactagagt cagttcctgt gcacgaccgt gagtgggatt actacgtctg cgaccagaga
    11701 atcaacgaca gaggcgtggc acttgataaa gagttagttg cttcggcttt gtattgtaaa
    11761 gatgttaaga tggaaagttt gtctggtgaa ctaaaggctc taacaggact tgataatcct
    11821 aatagcaggg cgcagctgct accgtggcta aaagaacacg gttattcggc taatgggctg
    11881 actaaagctg atgttgaaca ggaacttaag aaggccgaag gagagcttaa gagagtttta
    11941 gaacttaaac tacaaaccgc gatgtcaagt ctaaaaaaat atgaagctat ggaaagagct
    12001 atgtgctcag acggacgagt tcatgggcta cttcagtttt acggggctag ccggacagga
    12061 agatgggcgg gcagagttgt ccaagtacag aacttagcta ggaattatat aaaggatcta
    12121 gatgatgcta gagagtatgt taaaaagcgt gatattgatg ctgtggagat tttatacgat
    12181 agccttaacg acactttaaa gcagctcgtg cgaacggcac tcgtggctaa agatggctat
    12241 accttctatg tctctgactt ctcggcgatt gaggctaggg tgattgcatg gtttgctgga
    12301 gagcagtgga ggcttgacgt gttttctacg cacgggaaaa tctacgaggc gtctgccagt
    12361 cagatgttcg gaattccaat tgaggagatt gacaaggaac tacgccaaaa gggcaaaatt
    12421 tcagagttag cacttggcta tcaaggaggt cctggagcgc ttaagcagat gggggctcta
    12481 aatatgggag tcaaggaaga ggagcttcaa gggttagttg atgactggcg cagggccaat
    12541 aagaaaatcg tccaattttg gaaagacgta caaagagccg ccatcaaagc catcaaatcg
    12601 agagcaccga taaaacttgg aaaaatacga tttagatacc ggaaaggttt cctctttata
    12661 acattgccta gcggtaggaa cttagcttat gcaagagcca aggttgagcc aggcgactat
    12721 ggagacaaaa tcatctatga gggccaagga gatagggcct atttcacagc gcaagagacg
    12781 tacggcggta agcttgtcga aaatatcgtt caggcgacgg ccagggatat tctagctgaa
    12841 gcgcttctga ggattgaagc tgcaggctat gatgttgttt tccacgttca tgatgaggct
    12901 attatcgaag gttcaggcct gataatcgaa gaggttaatg atttgatggc tcaggctcct
    12961 gaatgggcgg agggtcttcc tttaaatagc gaaggctatg taacaaagta ttatatgaag
    13021 gattagatag atgaagcaag aaaaactaat agtaaagtct tctcccctgc aagagcttca
    13081 tatcgcaaca ggtagttcgc gaacagctaa gacatggaaa aatatcacgc taacttggca
    13141 ggagctggtt gagaggttag agaaacctac agtcacccaa gagacgtttg cggagtacca
    13201 gaagatgtct cgagcagaaa aagggcaagc aaaagacgta gggggctttg tcggtggatg
    13261 gctaaagcaa ggtaaacgga aaaatgaaaa cgttcaaagt aggtccttgg ttgcgcttga
    13321 cgcagatagc ccaagtaaag atttcttaga taggctagac ctgcttgcag attatgcatt
    13381 cgtactctac agtactcaca gccactcaaa aaaagctgct aagtaccgtc ttattatccc
    13441 tactgaccgt ttaatgatgc ctgatgaata tgagccagtc gctagatatt tggctaacca
    13501 actaggcatg tcaaactttg atgacacgac ttatcaaagc gtacgcttga tgttctggcc
    13561 gagccactca agagatgccg actttacgtt taaatataac gacgaggctt ttctgagtgt
    13621 tgatgaggtg cttgacacat acccggactg gcatgactca agcttctggc cagaaagccc
    13681 gacgcacgct gttaaaagac agcgtgaagc taaaaaacaa ggtgacccgc ttagtaaaaa
    13741 aggacttatt ggagcctttt gtcgtaacta tgacattaga caggccattg caacattctt
    13801 atctgaggtt tatgaagaag gaacgactcc tgataggtac acctacactg atggctcaac
    13861 cgcaaacggc ttagttatct atgatgatgt cttcgcttat agccatcacg ggacagatcc
    13921 cgtgggggat acgcttgtaa atgcctatga ccttgttcgt atccataaat tcggagagca
    13981 agatagcgag gctaaagata atactcctac taataagttg ccgtcaagta aagcgatgaa
    14041 tgcttttgtc tctgacttac ccgaaattaa agaccattta atggcggagg ctttaggcga
    14101 tttcgatgaa gagttaccag tcgaagatga cagaagctgg cttgaaattg atgagagggg
    14161 cgaaccggag gtcaatagtt atttgctagc aacgcagatt attaaggagg ttccgattta
    14221 ttgggatggc ttagaatttt tacgctacga cgctaaaaaa ggcatctggt tgccaaacgc
    14281 tgaggaatat ttgaagagtt atatctcaac taagaaactc ggtaaaatta ctaagattag
    14341 gcacattagc gaaaccgtcg tagcgattaa agcacaggct ttttcaagtg aagtgtttac
    14401 cgagagtgat cttaacaaga tagtgctagc gaatggagtc tatgacctga gggataacaa
    14461 ctttaagact aagtttgatc cagaattgca tgccaggtca agccatcccg ttgtctatga
    14521 ccccgaggcg acctgtgaaa cctttgaggg ttttcttaga gagaccgtcg gagctgaaaa
    14581 tatagatttc atctttgagt ggtttggcta taacttttat cgtgaataca ctattcaaaa
    14641 aatgctattc atctatggta gcgggggcac tggcaaatca acactaatta atattttacg
    14701 tgaaatgata ggcgctgata attattcagc cgtgacactg cagtacctga tgcaagaacg
    14761 ctttgcaaaa atcggcttat atcgtaagac agctaacttc gataccgatg ctaaacctca
    14821 atacttagca gatggcgcag cacttaaaat gttgacgggg gaggatacta ttcacgcaga
    14881 ccgtaagaat aaagagccga ttaactttta caattatgct aagctgtctt ttgccatgaa
    14941 tgagctccca cctatgcgag atttcagcgg aggacttaaa cgccgcatga tgatcctcga
    15001 gatggataag gttttaacgc aggaagttaa ggcgaaatac ccgctagata agattatgag
    15061 cgaggtgcct ggtatcttta acagagcgat ggaggggctt agaaaggcct taagtaagag
    15121 agatttcagt attagtgcca gcatgaggtc aagtgtcgag aaatgggaaa aaggcaacga
    15181 tgtcgtagct atgttccttg aagacgagtg tgaacttggc gaagacttca aagttcctgt
    15241 tagggatgtc tacccagctt ataaattcta ttgtcaggat tcaggctaca aacctttggc
    15301 aaaaaatgca tttaaccatc ggctaagaga gctaaattat gaaaataaaa acgttaaatc
    15361 tgatggaaag caagccaaaa attgggtcgg ctttaggtta aaaagtgagt tttaggggtt
    15421 acttttttgg aattagagtt tggtaaccct agaaaaaagt taccaagtta ccggtttttt
    15481 caaactttaa aaataaaaaa tttaaaaata atttttaaaa aaccaaaacc gaattggaaa
    15541 aatcggtaac ttagtaactc gacccttaga aatgggttcg aaaagtaacc ccggtagctt
    15601 tttggtagcc ctaagaggtc tttcatagca atagtttagc ccctgtggtt accaatctac
    15661 cacttttctt ctattaactt aaa
//
LOCUS       DAUGUF010000038        15483 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUGUF010000038 DAUGUF010000000
VERSION     DAUGUF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15483
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.038"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            88..657
                     /locus_tag="VIB71_001445"
     CDS             88..657
                     /locus_tag="VIB71_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ8823173.1"
                     /translation="MGKEIKVKCFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALADQT
                     DALQSEEAEVVQSDNAASDAWEKAATPIALDVKKTKDTKPVVKKEERQNVNTLPTTGE
                     ESNPFFTAAALAIMVSTGVLVVSSKCKEN"
     gene            895..1437
                     /locus_tag="VIB71_001446"
     CDS             895..1437
                     /locus_tag="VIB71_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8823174.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1446..2729
                     /locus_tag="VIB71_001447"
     CDS             1446..2729
                     /locus_tag="VIB71_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ8823175.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2745..3605
                     /locus_tag="VIB71_001448"
     CDS             2745..3605
                     /locus_tag="VIB71_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEQ8823176.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3607..4572
                     /locus_tag="VIB71_001449"
     CDS             3607..4572
                     /locus_tag="VIB71_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEQ8823177.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4683..5966
                     /gene="aroA"
                     /locus_tag="VIB71_001450"
     CDS             4683..5966
                     /gene="aroA"
                     /locus_tag="VIB71_001450"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEQ8823178.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDTLNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            5959..6450
                     /locus_tag="VIB71_001451"
     CDS             5959..6450
                     /locus_tag="VIB71_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ8823179.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6658..8109
                     /locus_tag="VIB71_001452"
     CDS             6658..8109
                     /locus_tag="VIB71_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ8823180.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYMMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8158..9546
                     /gene="rlmD"
                     /locus_tag="VIB71_001453"
     CDS             8158..9546
                     /gene="rlmD"
                     /locus_tag="VIB71_001453"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ8823181.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTIMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKIIYISCNPATMARDIKRYQELGYKLTKVQPVDLFPQT
                     HHVECVVLLIKE"
     gene            9585..10379
                     /locus_tag="VIB71_001454"
                     /pseudo
     CDS             9585..10379
                     /locus_tag="VIB71_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            10464..10865
                     /locus_tag="VIB71_001455"
     CDS             10464..10865
                     /locus_tag="VIB71_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEQ8823182.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKISLTMFVTGRRHNG"
     gene            complement(10970..12454)
                     /locus_tag="VIB71_001456"
     CDS             complement(10970..12454)
                     /locus_tag="VIB71_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEQ8823183.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQYHKLYRK"
     gene            12828..14048
                     /locus_tag="VIB71_001457"
     CDS             12828..14048
                     /locus_tag="VIB71_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ8823184.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGIAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     LSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     TIGQLKAERYQQLR"
     gene            complement(14168..14533)
                     /locus_tag="VIB71_001458"
     CDS             complement(14168..14533)
                     /locus_tag="VIB71_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEQ8823185.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            14647..15378
                     /locus_tag="VIB71_001459"
     CDS             14647..15378
                     /locus_tag="VIB71_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ8823186.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKEVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
BASE COUNT         4817 a         2687 c         3281 g         4698 t
ORIGIN      
        1 taataaaaga tggaattatt aattataatt tccaaattat cggtaattta atatgctaat
       61 gcatataaaa ataaaaaagg agaaacaatg ggaaaagaaa taaaagtgaa atgctttttg
      121 cgtagatcag cttttggatt agttgcggtg tcagcatcag tattagtcgg ttcaacagta
      181 tctgctgttg actcacctat cgaacagcct cgaattattc caaatggcgg aaccttaact
      241 aatcttcttg gcaatgctcc agaaaaactg gcattacgta atgaagaaag agccattgat
      301 gaattaaaaa aacaagctat tgaggataaa gaagctacga cagctataga agcagcaagt
      361 tcagatgcct tagaagcatt ggcggatcaa acagacgctt tacaatcaga agaagctgaa
      421 gtagttcaat cagataacgc tgctagtgac gcctgggaaa aagcagcaac tccaatcgct
      481 ttagatgtta agaaaactaa agatacaaaa cctgtagtta aaaaagaaga aagacaaaac
      541 gttaataccc ttcctacaac tggtgaagag tctaacccat tctttacagc tgctgcgctt
      601 gcaataatgg taagtacagg tgtgttagtt gtaagttcaa agtgcaaaga aaattagttg
      661 ctatttgttc tagcaaatga aacaagggaa tcgaaagatt ctctttttct gatatttaaa
      721 aatgctacag tttataatag cttgaaagac taaatgttct caaactcatt agaacaagct
      781 ttaataaaac taacccagtt gtatcaaagg atagataaag actaagactg ttatagaata
      841 tttgcaaaag atttgttata atggacccaa tacaggtatt gtgaaaggta taatatggat
      901 atttggacaa agcttgcagt gtttgctttt tttgagactc cgaaagtaat attacggcct
      961 tttcgctatg aagatcattg ggatttttac agcatggtta acgacactaa aaacctttat
     1021 tatgtttttc cagaacaaaa aactaaggca gcaagtgact atcttttagt acatagtttt
     1081 ataaagtttc ctttaggtca gtgggcaata gaagataaag caacccacca agtaataggt
     1141 tctattagaa ttgagcatta tgatgctaaa acgcgttgtg ctgatattgg ctatttttta
     1201 aactatgcct tttggggaca aggaattatg acagaagtcg taataaaact tgtttattta
     1261 tcttttcacg aatttggtct caaaacgttg cgtattataa ctcatttaga aaataaggcc
     1321 agccagaaag tagctaaaaa agcaggtttt caactaaaaa cctgttttaa aggaagtgat
     1381 cgtaatactc ataaaatctg catttataaa atgtaccaac taactaatga taggtgataa
     1441 tcattatgag caaacatcaa gatattttag attatttaga aaaacttgct attggtaaaa
     1501 aagtgagtgt tagaagcatt tcaaaccact taaaagtaag cgatggaaca gcctaccgtg
     1561 ctattaaaga ggcagaaaat cgaggtattg tcgaaaccaa accaagaagt ggaactgttc
     1621 gtattgaaaa aaaaggacgg gttcgtattg accgtctgac ctattccgaa attgctcgga
     1681 tcagtgattc ggaagtgcta gcgggacatg ctggtttagg acatgaattt agtaggtttt
     1741 caattggtgc tatgactcaa caaaatattc gtcgttactt ggtcaaagga gggttattaa
     1801 tagttgggga tcgtgaaacg attcaactct tagctcttga aaaccataat gccattttgg
     1861 tgacgggcgg atttccagta tccaaacgtg ttattgaaat ggcaaataac caacgaatcc
     1921 cagttatggt aactcattat gataccttta ctgtggcaac aatgattaat cacgcgctat
     1981 ctaatattcg tattaaaaca gatctcaaaa cagttgaaca ggtaatgata cctattacag
     2041 attatggtta cctttgcgaa gacagctctg ttgaagaatt caatacatta ataaaaaaaa
     2101 cacgacaagt caggtttcct gtattagatt ataaaagaaa agtgattggt gtagttagta
     2161 tgcgtgatgt ggtggatcag ttgccaacaa ctaagcttac caaggtcatg tctaaaaatc
     2221 caataacggc tagaccaaat actagtcttg ctaatattag ccagaaaatg atctttgaag
     2281 atttaaacat gttacctgtc actgacgaag aaaataattt acttggtatg attactcgta
     2341 gacaagcaat ggaaaatttg ccaaatcacc aaccaaataa cccctatact tatagtgagc
     2401 aaatactttc taaccttgaa gaaacggttg attattacca agtagtagtt gagccaacaa
     2461 tgattgatag tgctggtaac atgtcaaacg gtgttatttc agagttctta aaggaaatta
     2521 gtatcagagc cctcacgaaa aagcaccaaa aaaatatcat tatcgaacaa atgatggtat
     2581 actttttaca tgctattcaa attgaggatg aattaaaaat atatcctaaa atcattactg
     2641 aaaatagacg aagcagcacc attgatattg aaatttttgt ggatgatcaa gtgattgcta
     2701 aagctattat tacaacgaaa ataaattaga ggagtaacaa aacaatgata acattaaaat
     2761 cagcccgtga aatagaagcg atggatagag caggagactt cttagcaggt atccatattg
     2821 gcttaaggga tattattaag cctggtgtgg atatgtggga agtggaagca tatgttcgtc
     2881 gccgttgtaa agaagacaac gttcttcctt tgcaaatagg ggttgatggt cacatgatgg
     2941 actatcctta tgcgacctgt tgtggtctaa atgacgaagt agcacatgcc tttccccgtc
     3001 attacattct gaaagaaggg gatttgctta aagttgacat ggtactcagt gagcctttgg
     3061 ataaatcaat tgttgatgta gcagctttag attttgataa cgtgcctgag atgaagaaat
     3121 ggacaggatc ttataccggt ggtttagctg actcttgttg ggcttatgct gttggaacac
     3181 cgtctgacga aataaagcaa ttaatggatg tcaccaaaga agccatgtac cgtggtattg
     3241 aaaaagcagt aattggcaat cgtattggtg atattggcgc agctgttcaa gaatacgctg
     3301 aaagcttcgg ttatggtgtc gtgcgtgatc ttgttggtca cggtgttggt cctacaatgc
     3361 atgaagagcc aatggtacca aactatggaa cagcaggtcg tggacttcgt ctaaaagaag
     3421 gcatggtctt gactgttgag ccaatgatta atacaggaac ttgggaaatt gataccgaca
     3481 tcaagacagg ttgggctcat aaaaccctag atggtggttt atcttgccaa tacgaacacc
     3541 aatttgtgat tactaaagat ggtcccgtta ttttaacaag tcaaggagaa gaaagaactt
     3601 actaaaatgg cagaaaaaaa atggtttgat aaggtactgt ccaagtggca gtatgaaccc
     3661 attcaagtct ttatgaggca tttacaaagt gcagaaatgg atttatctgc cattgcggtt
     3721 gcgtattacc ttatcttaac ggcctttcca ttaattgtta ttgcagccaa tatttttcct
     3781 tacctcaata ttgatattgc tgatttgtta cgtttaatga agcaaaattt gcctaaagat
     3841 atttttagac cggcttctgc aattgtagaa aatattttct ctaaaccgtc tggaagtgtt
     3901 ttgggagtag cgactttgac aggattatgg acaatgtctc gaagtttgac atcgctgcaa
     3961 aaagctatta ataaagccta tggcgcttct cagcatcgag atttctttat cggacacttg
     4021 gttggtttgt tgaccagttt aattatttta tttttattag cctttgcctt aatcttttca
     4081 acattttcta aagctgctat tcaagtgctg gataagcatt accatttgag tgataatatc
     4141 acaacgattt tcttgctcct cattcaacct attacagttt tgattatttt tgttggcttg
     4201 atgctactat attttttatt acccaatgtt aagattaaaa aaattcgcta cattttacca
     4261 ggaaccctat ttacatcttt tgtgatgaca tttttgagta atctggttgg caattacgtt
     4321 gtgtataatg ttgagcggat ggtagatatt aaaatgtttg gttcagttat gatttttatc
     4381 atcatgctat ggtttatttt cttagcaaga atcctgattt taggagctat atttaatgcg
     4441 acctatcaag aaatgtcctt ggggaaatta gaaggtcgta gtggtgatat gatcgctatc
     4501 cttaaaaaaa cacttgggaa tgattcagat ctatctcctt cacagtctat cgaagatagt
     4561 cacactgatt gatacaaaaa agataataag tcgtggagtg agaaactatt ttcttgcttc
     4621 attttttatg aggatgaata gaaaatcatt gatcttagca aatagaaagg cagatgaaac
     4681 ggatgaaatt gcgaacaaat gcaggaccat tacagggaac gattcaagtt ccaggagaca
     4741 agtccattag tcaccgggca gtcatattag gagccgttgc taaaggggaa acacgagtaa
     4801 aaggactctt aaaaggagaa gacgtgcttt ccacgattca agcctttagg aatttggggg
     4861 tccgtatcga agaaaaagat gaccagcttg tgatagaagg tcaaggtttt caaggattga
     4921 ccgctccttg tcagacactt aatatgggaa attctggaac ctctatgcgc ctcattgctg
     4981 gattattggc aggtcaacct tttagtgtca aaatgattgg cgatgaaagc ttatccaaac
     5041 gtcctatgga tcggattgtt tatccgttaa agcaaatggg ggttgagata tctggagaaa
     5101 cagataggca atttcctcca ctacaattgc aaggtaatcg taatttacaa ccaatcacat
     5161 ataccttgcc tatctcttct gctcaggtta agtcagctat tttattagca gctttgcaag
     5221 caaaaggaac aacacaggtt gttgaaaaag agattactcg aaaccataca gaagaaatga
     5281 ttcaacaatt tggtggacga ttgatagttg atggtaaacg cattactttg gtgggacccc
     5341 agcagctcac tgctcaagag ataactgtcc ccggagatat ttctagtgca gctttttggc
     5401 ttgtcgccgg cttaattatt cctggctcgg agctcctttt aaagaatgtt ggagtcaatc
     5461 cgacacgaac agggattctt gaagtggttg aaaaaatggg agcacagatt gtctatgaag
     5521 atatgaataa gaaagagcaa gtaactagta ttcgagtggt atattctcac ttgaaaggaa
     5581 ctatcatatc aggaggtctt atccctcgat tgattgatga acttcccatc attgcacttc
     5641 ttgcaaccca agcacaagga acaacctgta ttaaagatgc tcaagaatta cgagtcaaag
     5701 aaacagatcg tattcaagta gtaactgata ctcttaacag tatgggagct aatatcaaag
     5761 cgacagcaga tggcatgatt atcaaaggcc ctacggtact atatggggct aacacaagta
     5821 cctatggaga tcatcgtatt ggtatgatga cagcaattgc agccttgctt gttaaacaag
     5881 gacaggtcca tttggataaa gaagaagcca tcatgacgtc ttatccgacg tttttcaaag
     5941 atttagaaag gctgtgtcat gactaaagtg ttattgggat ttatgggagt ggggaaaaca
     6001 acggtttcga aacacctaag tatgcactgt aaagatatgg atgctattat tgaagctaaa
     6061 atcggtatgt ctattgcagc tttttttgaa cagcatggag aaatagcatt tcgaacaatt
     6121 gaaagtcaag tgttaaaaga tctattgttt gcaaatgata acagtgtcat cgtaacaggt
     6181 ggcggtgtag tggttttaca agaaaatcga caattactga gaaaaaatca ccagcataat
     6241 attttattgg tagcttcttt tgaaactttg taccagcgtt taaaacatga taaaaagtct
     6301 caaagacctc tatttcttaa gtactctaag gaagcatttt atgaatttta tcaacaacgt
     6361 atggtatttt atgagggact ttcagattta gtaatcagag ttgaccatcg tacgcctgaa
     6421 gaagttgcca acatcattga gggttattag caggtcattg tcgtaatctg atatttatgg
     6481 ttttaaacag gtatctgtct aaagcacttc ttatggcaag ttggctttat taaatattag
     6541 gaaataatct tgattattct ataatgatta aaattttgag aggacaatct ggctaatata
     6601 ggttataatg gtagtattcg ttaaaagtgc aattgtaata ctaagagatg ataagatatg
     6661 acaaaatacc ccatgggtgg ccttagtcac catgaagaat tacgttattt ttatctccta
     6721 aggaatttga gttaccttag tgagaatgaa aaaaaagagt ttgctttttt aaaatctaaa
     6781 ttggaaattg gtcgagctta tgcgccttct aagcagcatt ataggaagtc aaaacggcaa
     6841 gaaccttact ttgaagatga ctactataac gactactcac caaatgattt actagaagat
     6901 gatgacgtca atcatgactc ttcttttgtt ccatatggtt taccgatata tcctaaagaa
     6961 gacagatatt taaacaaaaa aacaaaactt acagctcgta gacctataga tgctccgcag
     7021 cctattgatg aagacgatgc ttttttaaca gagtctgttg ctcgttgtgc tcttcctaga
     7081 tctcaaaaaa gaaagcataa gaaaaaagga tgtatgaaat ggttttttaa cattcttggc
     7141 ttattgctaa tgactgtgct tatggggtta gggttgatgt ttgcaaaagg ggtttttgat
     7201 atttctacta ataaagctaa ttacaaacca gctgtttccc aagcttttga tggtcaagaa
     7261 actcaagatg gtacgaacat tctggttttg ggttctgacc aacgagttac tcaaggttct
     7321 acagatgctc gcacagatac cattatggtt gtcaatgtcg gcaaccatgc taaaaaaata
     7381 aaaatggtct cttttatgcg tgacactttg attaacattc caggatacag ttataatgat
     7441 aattcgtatg atcttaaatt aaatagtgca tttaatcttg gagagcaaga agatcaccac
     7501 ggagcagagt acgttcgacg ggccttaaaa cataattttg atatcgacat taagtattat
     7561 atgatggtag attttgaaac atttgcagaa gctattgaca ccttgtttcc aaatggtgtt
     7621 aagattgatg ccaaatttgc gacagtaggt ggtgtagctg ttgactccgt agaagttcca
     7681 gatgacctgc gaatgaaaaa tggggttgtt cccaaccaaa ccatcgaagt tggagaacaa
     7741 cgcatggatg gtagaacctt gctcaactat gctcgtttcc gtaaagatga cgaaggagat
     7801 ttcggacgaa ccgtccgaca gcaacaggtt atgtcagctg ttatgtccca aatcaaggac
     7861 ccaactaaac tctttacagg gtctgcggct attggtaaaa tctatgcgct gacttcgacc
     7921 aatgtttctt ttccatttgt tgttaaaaat ggtgtttctg ttttaggaag tgggaaaaat
     7981 ggagttgagc acgtgaccat cccagaaaat ggggattggg ttgacgaata cgatatgtat
     8041 ggaggacaag ccctttacat agattttgat aagtatcaga aaacgttagc caaattaggt
     8101 ctgcgctaag atatggtata atggagagta actaaagttg ctcttctttt ttgagcaatg
     8161 gttagcccta gaaaaggaaa aagaataaga atgttgaaaa aaaatgatat tatccaagtt
     8221 gctatttcag atttaagcca tgagggagca ggtgtcgcta aacacgatgg ttttgttttc
     8281 tttgttgata atgcattgcc agaagaagtg attgacatgc gtgtcttaaa ggtcaataaa
     8341 aatagcggtt ttggcaaagt agaagcctat cattacctgt cgccagctag aaatgcagat
     8401 gtcaatttaa cttatttgcg aacaggcatt gcagaccttg gacatctaac ttatgaagac
     8461 caactgactt tcaaaaagaa acaagttcag gacagcctct ataaaattgc tggaatcagt
     8521 gacgtgacag tcgaaagcac gattgggatg acagaacctt tagcttaccg aaataaggct
     8581 caagttcctg ttagacgtgt taacggtcag ctagaaacag gctttttccg caagcattct
     8641 catgacttga ttcctatttc ggattattat attcaggaca aagagattga tcgtctcatt
     8701 aattttaccc gtgatttatt acgccgcttt gatattaaac cgtatgacga aacagaacaa
     8761 acaggtctct tgagaaatat tgttgttcgc cgaggccatt actctggaga aatgatgctg
     8821 gtcttagtga ctacacgccc aaaagttttc cgtgttgacc aagtcattga aaaaatcgtt
     8881 gaagcttttc cagcagtggt gtctattatt caaaatatta atgataagaa caccaatgca
     8941 atctttggta aagatttcaa aacgctttac ggcaaggata ccattactga tagcatgctt
     9001 ggaaacaact atgccatttc tgctcagtct ttctaccaag tgaatacgat tatggcagaa
     9061 aaactctatc aaacagctat agccttttca gacctttcta aagatgacat tgtgattgac
     9121 gcctactcag gtatcggaac cattggccta tcatttgcta aaacagttaa agctgtttat
     9181 ggtgttgaag tgattgaagc agctgttaga gatgctcaac agaatgccgc tcttaatggc
     9241 atcaccaatg cctactttgt cgcagatacc gcagaacatg ccatggcaac atgggcgaaa
     9301 gatggcatta aaccaagtgt tattctggta gacccgccac gaaaaggctt aacagaaagt
     9361 ttcatccaag ccagcgtggc aatgggacca caaaaaatca tctacatttc ctgcaaccca
     9421 gccaccatgg cgcgtgacat caagcgttat caagagttgg gttacaaact gaccaaagtg
     9481 cagcccgtag atttgtttcc gcaaacgcat cacgtcgagt gtgtagtgtt gctaatcaag
     9541 gagtaaggta gctgcctcca catgacaaaa ataaggagaa acgaatgcct attacccaac
     9601 acgagattcc ccttttagaa tgtgatagta atccatcagc cgtcgttata cctacacatg
     9661 aaggtctagc tatttagctt ccagctaagt gtgtctatgc tttcttagaa gacgagattg
     9721 aagcttttgc tttagaccat caaggtaaaa aaagtagcag aattcatttc agccacaaag
     9781 gtttaccctg tttatcagat atcttataaa ggtcaagaca tttgcctagc tcaagctccc
     9841 gttggctcag ctcctgcggc gcaattcatg gactggctga ttggttatga ggttaaagaa
     9901 atgatcagta caggaacctg tggcgttttg gttcctatcg cagaaaaccg ttttttagtg
     9961 ccagttaagg ctttgcgaga tgaaggaaca agttatcatt acgtggcacc atctcgttat
    10021 attgatattg atcctaagat gcttagactg attgagaaaa gcttttagca caggggttag
    10081 cttatcaaga ggtcatcacc tggtcaacag atggttttta ccgagaaacc aaagaaaaag
    10141 tggcttatcg ccaggaagaa gggtgttcgg ttgttgagat ggaatgttct gccttagcag
    10201 cagtagctca attaagaggc atcctttggg gacaactctt atttacagca gatactctag
    10261 cagatgtaga ggtttacgat caacgcaact ggggcgctga ttcctttagt tttgcgctcc
    10321 atttatgctt ggaagtactc aatacgctag aaaaggatgg aaaggctact gatttttgaa
    10381 acatgagctc tgccttctgt tcctatttgt agtataatga ggcttgtatt gcttttagac
    10441 taagcttaga aaagagaaaa acaatgtcag atttaacaca agagatgacc ttaaatgtta
    10501 ttagtatttt tgataattac caaattgaac ttgctgaaaa aggacacctt attttaagta
    10561 ctgaagtgac tgagacggct ttgaattatt atgggaatgc ccatggtggt tatcttttca
    10621 ccctatgtga tcaagtaggt ggtttggttg ctagaactac tggcgtagaa tctgtcacct
    10681 tacaggccaa tgctaactat ttaaaagcag ggcacaaggg agacaagctg atggttgaag
    10741 gtcgattggt tcatggaggt cgaaccacgc aggtggttga tgtgacgatt cataaccaaa
    10801 caggagctct tctaacaaaa ataagcttga ccatgtttgt gactggccga cgtcataacg
    10861 ggtgattaat gaatcaataa aggaaaaaag tcccaactct ctgagaattg ggactttttt
    10921 cctttattga gagataccat aaatcacccg ttagacgggt ggttatggtt tatttacggt
    10981 aaagtttgtg atattggtaa acagggtcaa aggtaatatt taccccaagt tttcggagta
    11041 catttttatc ttcttcggtt aagataacgg tagaatgggc ttcgctacct ttcaaattgc
    11101 caagttcttt catggctaga ttagcttctt cactagtcat agcagtaatg gccaacgcaa
    11161 tcagaatttc attggaatga agccgcggat tgtgactgcc taagtggttc actttgaggc
    11221 cttgaatagg tttcacgtat tcgggttcaa tcaaatgagt ggttttatca atctttgcca
    11281 aggttttaat cgcattgatg ataacagctg cagttggtcc aaagagttca gatgttttac
    11341 ctgtcacaat ctgcccattt ggtagttgga gagcaagggc aggttggcct gtttgctctg
    11401 ctttttgatg agcagctaca gtaacgtgac gatcgtcagg ggtgacaccg atatcattca
    11461 tcaagagctc aatttttttg acagcagatt ctgtgactcg ctctgcctta aaatccacga
    11521 gggtttggta ataacgacgg atgatttctt gtttagaagc ttcgatagca gcttcttcat
    11581 tgacgataga aaaaccaacc atgttaacac ccatatcggt tggtgaggca taaggagact
    11641 tgctcaaaat acgctcgaag gtccgattta agacaggaaa gacctcgata tcacggttgt
    11701 aattaacggc cgttttgcca taagtttcca aatggaaggg gtcaatcata ttcacatcat
    11761 ctaggtctgc cgtggctgcc tcataagcca gattgacagg gtgatgaaga ggaagattcc
    11821 aaactgggaa ggtttcaaat ttagcatagc cagacttaac cccattgatt tggtcgtgat
    11881 acatttggga catgcaagtg gctaattttc cagacccagg gcctggtgct gtaacaacga
    11941 taaggttacg actcgttttg atgtaatcat ttttccccat cccctcagat gagataatat
    12001 gattaatatc tgtcgggtag cccttgatag gataatgcag gtaagaagca atgccatttt
    12061 tttcgagttg cttgcgaaag gcatctgcag cgggttggtt attgtattga gtaataacga
    12121 cagaacctac gtaaatatct aacgtgttaa atttgtcaat taagcgaaag acttcttggt
    12181 cataagaaat gcctaaatca ccacgcgctt tagaatgttc aatattatta gcgttaatgg
    12241 caattacaat ttcgacttgt tctttgagct ctttgagtaa tttaatctta ttgtcaggtt
    12301 catagccagg aagcacacgg gcagcatggt aatcttctaa cattttacca ccaaattcca
    12361 tgtaaagctt gccatcaaat tggctgatac gttctaaaat atgatctctt tgcaagttta
    12421 aatacttgtt agaatcaaaa gcaatagtct tcattttttc acctctgtaa agcattataa
    12481 caaagaaatt ccaagaaaga aaaggttttt tgcagggata cctcattttg tgacttttta
    12541 aaaaaactta ggcttggttc ttagaagaaa aatgtatccg ctatgttcaa aagaacttga
    12601 caattaaaat gagctttact atactagtaa caattaaata ctattttaaa catgttccgt
    12661 gaagcatgaa agtcttaaca gtaaagagag tttttttgtc atctcttatt atttagtgaa
    12721 ctttgatgga cttgcggact tgtttccaag tctttttttg acctttggac aaagggtatt
    12781 caattaatta aggtagtcag tgagctacta ttaagaagga gacaattatg tcaacattat
    12841 cattggacac cacaaataag cgagctttag tggcagctat tgcagcttca ggaacggatg
    12901 acttgaatgt catgtttctt gccttttcca tgtcctccat tatgacagac ttggggctta
    12961 gtggcactca gggtggctgg attgcgacca ttaccaattt aggaatgttg gtgggaggcc
    13021 tcttattcgg gttgctggct gataggcacc acaagtttaa ggtctttaaa tggacgattt
    13081 tactgttttc agtagcaaca ggattaattt attttaccca gtctttgccc tacttgtact
    13141 tgatgcgatt tattgctggc ataggagttg gaggtgagta cggtatagcc attgctataa
    13201 tggcagggat tgtaccacca gaaaaaatgg gtcggatgtc ttctttaaat ggtattgctg
    13261 gccagcttgg ctccattagt tcggctcttt tagcagggtg gctggctcta agtctaggct
    13321 ggcgtggcct ttttctcttt ggattacttc cgattctctt ggtgatttgg atgactttag
    13381 ccatagatga ccaaaaaatt tgggatcatt atgggcaaga ggaggaagaa tgcagtcaac
    13441 caattaaaat caatgaacta ttcaaaacaa aatccttaac agctcaaacc cttgctttaa
    13501 tggtcatgac gactgtgcag attgcgggct attttggaat gatgaattgg ttgccaacca
    13561 ttattcaaac aagcttaaac ctttcagtaa aaagttcgtc cttgtggatg gtggctacta
    13621 ttgtcggcat gtgtttgggg atgctgtgtt ttggtcagct tttagattgc tttggtccac
    13681 gtctgattta ttccctcttt ttattagcat catctatttg tgtttacctt tttcaatttg
    13741 ccaattccat ggcgagtatg gttattggag gtgctattgt cggttttttt gtcaatggga
    13801 tgtttgctgg ctacggggct atgattacca gactttatcc ccatcacatt cgatccacgg
    13861 ctaataatgt tattttgaat gttggccgtg ctctaggagg attttcgtcc gttgctattg
    13921 gtagtatttt agatgcctca ggtatttcaa tggtcatgat tttcctagct tctctgtatg
    13981 tgattagttt tggagccatg tggactattg gtcagttaaa agcagaacgc taccaacaat
    14041 tgcgttagca aagagatggg tgttagtatt tgagttactt tcactcacaa aactatttta
    14101 ttgattgaga taagcaaaaa ggtaagcgct tagggattgc ttaccttttt ggttcttttc
    14161 ttttgtttta ctccgctact ttggccataa aatgtttact gttcacccta actctagtat
    14221 gacaggcttt tccaatgagt tgttctccca caaaagcttc caagcggaaa tcgtattttc
    14281 ggccttcttc tttaagggct gtaatgatga ttgtaacagg atctccaatg gctgaagctg
    14341 ccaaatgttg gatagctatc tcgctgccaa ccgttgtaaa gtcactgtcg agctgttctt
    14401 gggcaaataa gtaagaagca ttttccataa aagcaacaag agcaggagta gctaggacat
    14461 tcagcgttcc tgagcccatg gctttagccg aatgattggg acgggtttca taagtgtgag
    14521 aataaatagt cataagttaa tctcctcgtt tctataagcc tattataata tattaagcgc
    14581 ttacagtcat gaagccactg ttttttatgt tatacttaat aatgaatttt ctttgaaagg
    14641 gttatgatgc gcttagataa atttttagtg gcaactggtg ttggaactag gagccaagtc
    14701 aaacttctct taaaaaagaa ggctattttc gtcaatcaaa aggttgaaac ctctgccaaa
    14761 gcacacattg atgaatacaa ggatttagtg acgtatcaag gcacgccctt ggtctatgaa
    14821 tcctttgttt attacctgtt aaacaagccg tcagggtatg tgtcagcaac ccaggacaga
    14881 cagcaggcta ctgttatgga gttgttagat gacacggcta ggcaaaaagc agtttttcct
    14941 gtgggtaggt tagataagga tacccgtgga cttttgctct tgaccaataa tggacaacta
    15001 gcccatgacc ttttatcccc taaaaaacat gttacgaaag agtacttggc taaagtagca
    15061 ggcatcatga ctgaagctga taaagattat tttgctagag gtatttcctt aaaggatcac
    15121 cagtgcctac ctgctcattt agaagtgctt gctagtgatt tacagcagca aacaagtttg
    15181 gttaaaatta ccatacaaga aggaaaattc catcaggtga aacgcatggt agcagcctgt
    15241 ggaaaggaag tgcttgactt acagcgtctc agcatgggac cattaaaact agaccctagc
    15301 cttgcagaag gggagtttag gcgcctgacg cctgaggaat tgcaaagcct ggcaccttat
    15361 tgtcagagct cactataaaa agaaacctcc cctgtcagta ctgaccccaa aaagttggac
    15421 aaataattat tgaaaggatt tagttctgta ttggacagga ctaagtcctt ttagttttgc
    15481 ttt
//
LOCUS       DAUGUF010000039        13790 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUGUF010000039 DAUGUF010000000
VERSION     DAUGUF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13790
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.039"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            31..1254
                     /locus_tag="VIB71_001460"
     CDS             31..1254
                     /locus_tag="VIB71_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEQ8823187.1"
                     /translation="MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            1313..2119
                     /locus_tag="VIB71_001461"
     CDS             1313..2119
                     /locus_tag="VIB71_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEQ8823188.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            2352..3707
                     /gene="dnaA"
                     /locus_tag="VIB71_001462"
     CDS             2352..3707
                     /gene="dnaA"
                     /locus_tag="VIB71_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEQ8823189.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            3862..4998
                     /gene="dnaN"
                     /locus_tag="VIB71_001463"
     CDS             3862..4998
                     /gene="dnaN"
                     /locus_tag="VIB71_001463"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ8823190.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            5073..5270
                     /locus_tag="VIB71_001464"
     CDS             5073..5270
                     /locus_tag="VIB71_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEQ8823191.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            5600..6715
                     /gene="ychF"
                     /locus_tag="VIB71_001465"
     CDS             5600..6715
                     /gene="ychF"
                     /locus_tag="VIB71_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEQ8823192.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNILQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEGKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMAYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            6785..7354
                     /locus_tag="VIB71_001466"
     CDS             6785..7354
                     /locus_tag="VIB71_001466"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEQ8823193.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            7357..10860
                     /gene="mfd"
                     /locus_tag="VIB71_001467"
     CDS             7357..10860
                     /gene="mfd"
                     /locus_tag="VIB71_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEQ8823194.1"
                     /translation="MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GIFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFTDNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYKRLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEREIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVSELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYISDERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            11022..11294
                     /locus_tag="VIB71_001468"
     CDS             11022..11294
                     /locus_tag="VIB71_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEQ8823195.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            11281..11652
                     /locus_tag="VIB71_001469"
     CDS             11281..11652
                     /locus_tag="VIB71_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEQ8823196.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKRTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            11787..13073
                     /locus_tag="VIB71_001470"
     CDS             11787..13073
                     /locus_tag="VIB71_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEQ8823197.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            13070..>13790
                     /gene="tilS"
                     /locus_tag="VIB71_001471"
     CDS             13070..>13790
                     /gene="tilS"
                     /locus_tag="VIB71_001471"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ8823198.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQ"
BASE COUNT         4875 a         2147 c         2472 g         4296 t
ORIGIN      
        1 gctatggaca aataattcgg aggacaaaac atgccaagta tgaaacatat cttaaaatcc
       61 ttaagtattt tactaattgg atttttagga ggattaatag caattattac attcaataat
      121 ctctacccac attctccatc aaaaataaat tcaggtaagg caacaactag taatatggtt
      181 tttaacaaca caaccaatac tactaaagct gtcaaagctg ttcaaaatgc agttgtatca
      241 gttattaatt atcaagataa cccttcttca tccctttcta acccttatac aaaactcttt
      301 ggagaagggc gttcaaaaga gaataaggat gctgaattat ctatttttag tgaaggatct
      361 ggggtcattt atcgaaaaga tggcaactcc gcttacgttg ttactaataa ccatgttatc
      421 gacggagcta aacgaattga aattcttatg gcagacggat ctaaagttgt tggtgaatta
      481 gttggagctg atacttattc ggatttagct gttgttaaga tctcttcaga taagataaaa
      541 acagtagctg aatttgcaga ttctacaaaa ctaaatgttg gagaagttgc tattgctatc
      601 ggcagcccac taggaacaca atacgctaat tctgttactc aaggaatcgt ctctagttta
      661 agtcgtactg taactttaaa aaacgagaat ggtgagactg tctcaacaaa tgctattcag
      721 acagatgctg ctattaaccc tggaaactct ggtggaccac taattaatat tgaggggcaa
      781 gtaatcggaa ttaattcaag taaaatttct tctaccccaa ctggtagcaa cggtaatagt
      841 ggtgctgttg aaggaattgg ttttgctatc ccatctactg atgttattaa aattattaaa
      901 caactagaaa ctaatggtga agttatcaga cctgctcttg gaatatccat ggtcaattta
      961 aatgacttat ccacaaatgc tcttagtcaa attaatattc caactagtgt aactggtggt
     1021 attgtagtag cagaagttaa ggaaggaatg ccggcatctg gcaaacttgc tcagtacgat
     1081 gtgattacag aaattgatgg caaaacagtt aattcaatta gtgatttaca aagtagtcta
     1141 tacggacacg atattaatga tactattaaa gtaacttttt atagaggaac tacaaagaaa
     1201 aaagcagata tcaaattaac aaaaactact caagatttga ctaaaacgca gtaaacaagc
     1261 tacctaaata ctattacatt ttatcacata aaacagtcca aaggactgtt ttatgtttct
     1321 tattctatcc aggaactccc ttatgacaaa agaattattg atagacctac caattgaaga
     1381 tattgttaca aatccctatc agccaaggat acaatttaat caaagagaac tccaagacct
     1441 agcaacttct attaaatcaa acggcctcat tcaacctatt attgttcgaa aatctgacat
     1501 ttttggctat gagttagttg ctggagaacg acgacttaaa gcttcaaaaa tggctggtct
     1561 aaaaaaagtt ccagctatca tcaagaagat ctccacactc gagagcatgc aacaagctat
     1621 agttgaaaat ttacaacgtt ctaaccttaa cgctatcgaa gaagctaaag cctatcagtt
     1681 attggttgaa aaaaaacaca tgactcacga tgagattgct aaatatatgg gaaaatcaag
     1741 accttatatt agcaatacct tacgtctgtt acaactccca gcacctatca ttaaagcaat
     1801 tgaagaagga aaaattagtg cgggacacgc gcgtgctctt ttaactttga gtgatgataa
     1861 gcaacaactg tacctcactc ataaaataca aaatgaaggc ctaagtgtta ggcaaattga
     1921 gcaactggtt acttctactc caagttcgaa gctatctaaa aaaactaaaa atatttttgc
     1981 cacttcttta gagaaacaat tggctaaatc attgggactc tctgtcaata tgaagctgac
     2041 agcaaaccat agtgggtacc ttcagatatc tttttccaat gatgatgaat taaacagaat
     2101 tatcaacaag ctaaagtagc ttgttgatat tctgtttttt cttttttagt tttccacatg
     2161 aaaaatagtt gaaaacaata gcggtgtcac cttaaaatgg cttttccaca ggttgtggag
     2221 aacccaaatt aacagtgtta atttattttc cacaggttgt ggaaaaacta actattatcc
     2281 atcgttctgt ggaaaactag aatagtttat gatagaatag ttctagaatt atccacaaga
     2341 aggaacctag tatgactgaa aatgaacaaa ttttttggaa cagggtcttg gaattagctc
     2401 agagtcaatt aaaacaggca acttatgaat tttttgttca tgatgcccgt ctattaaagg
     2461 tcgataagca tattgcaact atttacttag atcaaatgaa agaactcttt tgggaaaaaa
     2521 atcttaaaga tgttattctt actgctggtt ttgaagttta taacgctcaa atttctgttg
     2581 actatgtttt cgaagaagac ctaatgattg agcaaaatca gaccaaaatc aatcaaaaac
     2641 ctaagcagca agccttaaat tctttgccta ctgttacttc agatttaaac tcgaaatata
     2701 gttttgaaaa ctttattcaa ggagatgaaa atcgttgggc tgttgctgct tcaatagcag
     2761 tagctaatac tcctggaact acctataatc ctttgtttat ttggggtggc cctgggcttg
     2821 ggaaaaccca tttattaaat gctattggta attctgtact attagaaaat ccaaatgctc
     2881 gaattaaata tatcacagct gaaaacttta ttaatgagtt tgttatccat attcgccttg
     2941 ataccatgga tgaattgaaa gaaaaatttc gtaatttaga tttactcctt attgatgata
     3001 tccaatcttt agctaaaaaa acgctctctg gaacacaaga agagttcttt aatactttta
     3061 atgcacttca taataataac aaacaaattg tcctaacaag cgaccgtaca ccagatcatc
     3121 tcaatgattt agaagatcga ttagttactc gttttaaatg gggattaaca gtcaatatca
     3181 cacctcctga ttttgaaaca cgagtggcta ttttgacaaa taaaattcaa gaatataact
     3241 ttatttttcc tcaagatacc attgagtatt tggctggtca atttgattct aatgtcagag
     3301 atttagaagg tgccttaaaa gatattagtc tggttgctaa tttcaaacaa attgacacga
     3361 ttactgttga cattgctgcc gaagctattc gcgccagaaa gcaagatgga cctaaaatga
     3421 cagttattcc catcgaagaa attcaagcgc aagttggaaa attttacggt gttaccgtca
     3481 aagaaattaa agctactaaa cgaacacaaa atattgtttt agcaagacaa gtagctatgt
     3541 ttttagcacg tgaaatgaca gataacagtc ttcctaaaat tggaaaagaa tttggtggca
     3601 gagaccattc aacagtactc catgcctata ataaaatcaa aaacatgatc agccaggacg
     3661 aaagccttag gatcgaaatt gaaaccataa aaaacaaaat taaataacat gtggaaaaga
     3721 atatctttta tgaaatagtt atccacaagt tgtgaacaac catttagtct tggattctct
     3781 cgtttattta gagttatcca ctatatacac aagacctact actactactt attattatac
     3841 ttattaaata aaggagttct catgattcaa ttttcaatta atcgcacatt atttattcat
     3901 gctttaaatg caactaaacg tgctattagc actaaaaatg ccattcctat tctttcatca
     3961 ataaaaattg aagtcacttc tacaggagtc actttaacag ggtctaacgg tcaaatatca
     4021 attgaaaaca ctattcctgt aagtaatgaa aatgctggtt tgctaattac ctctccagga
     4081 gctattttat tagaagctag tttttttatt aatattattt caagtttgcc agatattagt
     4141 ataaatgtta aagaaattga acaacaccaa gttgttttaa ccagtggtaa atcagagatt
     4201 accttaaaag gaaaagatgt tgaccagtat cctcgtctac aagaagtatc aacagaaaat
     4261 cctttgattt taaaaacaaa attattgaag tctattattg ctgaaacagc ttttgcagcc
     4321 agtttacaag aaagtcgtcc tattttaaca ggagttcata ttgtattaag caatcataaa
     4381 gattttaaag cagtagcgac tgactctcat cgtatgagcc aacgtttaat cactttggac
     4441 aatacttcag cagattttga tgtggttatt ccaagtaaat ctttgagaga attttcagca
     4501 gtatttacag atgatattga gaccgttgag gtatttttct caccaagcca aatcttgttc
     4561 agaagtgaac acatttcttt ttatacacgc ctcttagaag gaaattatcc cgatacagac
     4621 cgtttattaa tgacagaatt tgagacggag gttgttttca atacccaatc ccttcgccac
     4681 gctatggaac gtgccttctt gatttctaat gctactcaaa atggtactgt taagcttgag
     4741 attactcaaa atcatatttc agctcatgtt aactcacctg aggttggtaa ggtaaacgag
     4801 gatttagata ttgttagtca gtctggtagt gatttaacta tcagcttcaa tccaacttac
     4861 cttattgagt ctttaaaagc tattaaaagt gaaacagtaa aaattcattt cttatcacca
     4921 gttcgaccat tcaccctaac accaggcgat gaggaagaaa gttttatcca attaattaca
     4981 ccagtacgaa caaactaagt aagaaaaagc tcccttttag gagttttttt gttattataa
     5041 atattaacga taatataagt ggagaaaagg gaatgtatca aattggatca tttgttgaaa
     5101 tgaaaaaacc tcatgcttgt gtaattaaag aaactggtaa aaaggctaat caatggaagg
     5161 tactgagagt aggagctgat attaaaattc agtgtactaa ctgtcagcat gtgattatga
     5221 tgagtcgtta tgattttgag cgaaaattaa aaaaagtact gcaaccatga aagtcctttt
     5281 aaataaataa ttctagctat atttgcaacc aatactttcc taaaaaattg ctagtatgcc
     5341 gttggaaaat tagctattct aatgttatcg aaagaagaaa ggtggccatt gacaatgacg
     5401 aaagttgtag cacagttact tagtttctcg gcaaactata tcaaaatgag aataatacac
     5461 caaactttga taatttaaat gaaggtgaaa gagtggcata atgataagca aatctgaaat
     5521 tttcttctta ttcataccgc tttttcttct attttttggt ataataatct tgattgaaat
     5581 ttgaatggag attcgctaaa tggctttaac agcaggtatt gtaggcttac caaatgttgg
     5641 taaatcaacc ttatttaacg caattacaaa agcaggagca gaagctgcta attatccttt
     5701 tgcgactatt gatcccaatg ttggtatggt agaggttcca gatgagcgtc tgcaaaaatt
     5761 gacagaattg attacaccta aaaaaacagt tccgacaacc tttgaattta ctgatattgc
     5821 aggtattgtt aaaggtgctt ctagagggga aggtctagga aataaatttt tagctaatat
     5881 tcgtgaagtc gatgctattg ttcatgtggt acgtgctttt gatgatgaaa atgtcatgcg
     5941 tgaacaaggt cgtgaggatg ctttcgttga tcctatagca gatattgaca ctattaatct
     6001 tgaattaatc ttagctgatt tagagtcaat caataaacgt tatgcgcgtg ttgaaaaaat
     6061 ggcacgaact caaaaagata aagaatcagt agcagagttc aatattttgc aaaagattaa
     6121 acctgttttg gaagatggga aatcagctag gacaattgag tttacagaag atgaagcaaa
     6181 agttgttaaa ggtctctttt tattaacaac taaacctgtt ttatatgtag ctaatgtcga
     6241 tgaaggtaaa gttgctaatc cagatggtat tgattatgtc aaacaaattc gtgactttgc
     6301 agctactgaa aatgctgaag tagttgttat ctcagcgcgt gcagaagagg aaatttcaga
     6361 gcttgacgat gaggataaag aagaattttt ggaagctatc ggtcttactg aatcaggcgt
     6421 tgataaatta accagagcag cttatcatct cttaggcctt ggaacctatt ttacagcagg
     6481 tgaaaaagag gttcgtgctt ggacgtttaa gcgtggtata aaagctccac aagctgctgg
     6541 tattatccat tcagattttg aaagaggttt tattcgtgca gtaaccatgt cttatgatga
     6601 tctaatggcc tacggttcag aaaaagccgt caaagaagct ggacgcttgc gtgaagaagg
     6661 aaaagaatat gttgtccaag atggggacat catggaattc agatttaatg tgtaattata
     6721 ttaaaacaat atcagaaggt tggaagaaca ttccagccct tttggcattt tagaaagaga
     6781 aaatatggta aaaatgattg ttggtctggg aaatccaggc tctaaatatg aaaaaacaaa
     6841 gcacaatatt ggttttatgg ctattgacaa tattgtcaag aaccttgacg ttacctttac
     6901 agatgataaa aattttaaag cacagatagg aagtactttt attaatcatg aaaaagttta
     6961 ctttgtgaaa cctactactt ttatgaataa tagcggcata gcagtaaaag cattactaac
     7021 ctactataat attgacataa cagatttaat tgttatctat gatgatttag acatggaagt
     7081 cagtaaatta cgtttacgta gtaagggttc agcaggagga cataatggca ttaagtcaat
     7141 cattgcccac attggaactc aggaatttaa ccgaatcaaa gttggtattg gacgaccttt
     7201 aaaaggtatg actgttatta accatgtgat gggccaattc aataccgaag ataatattgc
     7261 tatttcgtta actcttgaca gagttgtcaa tgctgtcaag ttttatttac aagaaaatga
     7321 ttttgaaaaa acaatgcaga aatttaatgg ataatcatga atattttaga attatttagt
     7381 cagaataaga aagtccaatc ctggcactct ggattaacca ccttaggaag acaactggta
     7441 atggggttat cgggttcaag taaagcattg gctatagctt ccgcttattt agatgatcaa
     7501 aaaaaaatag ttgtggttac atcaactcaa aatgaggttg aaaaattagc cagcgattta
     7561 tctagtttac ttgatgaaga acttgttttc caattttttg cagacgatgt ggctgcagcg
     7621 gaatttatct ttgcgtcaat ggataaagct ctatcaagaa tagaaaccct gcaattttta
     7681 aggaatccta aatctcaggg cgttttaatt gttagtttat caggcttaag aactttattg
     7741 ccaaacccag atgtttttac aaagagtcag attcaactaa cagttggaga agattatgat
     7801 agtgatactc ttactaaaca actgatgaca attggatatc agaaggtctc acaggttatt
     7861 agtccgggag aatttagccg tcgaggggat attttagata tctatgagat tacacaagaa
     7921 ttgccttatc gattggaatt ttttggtgat gatattgata gtattaggca atttcatcca
     7981 gaaactcaaa aatcttttga acaactagaa ggtattttta ttaatccagc aagtgatctt
     8041 atttttgagg ctagtgattt tcaacgtggc attgagcaat tagaaaaggc tctacaaaca
     8101 gcacaagatg ataaaaaatc ttatttagaa gatgtattag ctgtttcaaa aaacggtttt
     8161 aaacataagg atatccgtaa atttcaatca ttattttatg aaaaagagtg gtcattatta
     8221 gattatattc ctaagggaac gccaatcttt tttgatgatt ttcaaaaact agttgataaa
     8281 aatgcaagat ttgatttaga gattgctaat ctcttgacag aagatttaca gcaaggaaag
     8341 gctctttcca atcttaacta ctttacagat aattatcgag agcttaggca ctataagcca
     8401 gcgaccttct tttcaaattt tcataaggga cttggaaata tcaaatttga tcagatgcat
     8461 cagctaactc agtatgccat gcaggaattt tttaatcaat ttcctttgtt gattgatgag
     8521 attaaacggt atcaaaaaaa tcaaacaacg gttattgtac aggtagagtc tcagtatgct
     8581 tacaaacgac ttgaaaaatc ttttcaagat taccaatttc gccttccttt agtgagtgct
     8641 aatcaaattg tttcacgtga atcacaaatt gtaattggag ctatctccag tggtttttat
     8701 tttgctgatg aaaagttagc gttaatcaca gagcgtgaaa tttatcataa aaagatcaaa
     8761 cgacgcgcta gacgatctaa tattagcaat gctgagcgtt tgaaagatta caatgagtta
     8821 gcagtaggtg attacgtggt tcataatgtc catggtatcg gtcgctttct tggaattgaa
     8881 acgattcaga ttcagggaat ccatcgagat tatgttacta ttcaatatca aaattcagac
     8941 cgtatttctc ttccaattga ccaaattggt agcttatcaa agtacgtttc tgctgatgga
     9001 aaagaaccta aaattaataa actcaatgat ggtcgtttcc aaaagacaaa gcaaaaggtc
     9061 gctagacaag tagaggatat tgctgatgac cttctaaaat tatatgctga aagaagtcag
     9121 caaaaaggat tttcattttc accagatgat gacttgcagc gcgcttttga tgatgatttt
     9181 gcttttgtag aaacagaaga tcaacttagg tctataaagg aaattaaagc tgatatggag
     9241 agcatgcagc ctatggatcg tcttttagta ggcgatgtag gatttggtaa gacagaagta
     9301 gctatgaggg cagcctttaa agcggtgaat gatcacaaac aagtagctgt cttagttcca
     9361 accacagtct tggcccagca gcattatgaa aacttcaaag cacgctttga aaattaccct
     9421 gttgaggttg acgtcttaag tcgtttccgt agtaaaaaag agcaagctga aacactagaa
     9481 cgtgtacgaa aaggtcaaat tgacattatt atcggaaccc atcgactcct atcaaaagat
     9541 gtggtctttt ctgatttagg attgattgtg attgatgagg aacaacggtt tggtgttaag
     9601 cataaagaaa ctttaaagga attaaaaact aaggttgacg tcttaacctt aacagctact
     9661 ccgattccta gaaccttaca catgtctatg ttaggtatcc gagatttatc ggttattgag
     9721 accccaccaa ccaatcgtta tcctgttcaa acctatgttt tggaaaataa tccaggtctc
     9781 gttagagaag ctatcattcg tgaaatggat cgtggaggac aaatttttta cgtttataat
     9841 aaagttgaca ctattgaaaa gaaagtttca gagctacaag aattagtccc agaagcttct
     9901 ataggttttg ttcatgggca aatgagtgaa attcaacttg aaaatacctt gattgacttt
     9961 ataaatggtg attatgatgt ccttgtggct acaacaatca tcgaaacagg agttgacatt
    10021 tctaatgtaa acactttgtt tattgagaat gctgatcata tgggattgtc aactttatat
    10081 caactacgag ggcgcgtcgg aagaagtaat cgtattgctt atgcttacct gatgtatcgt
    10141 cctgataagg tcctaacaga ggtttctgaa aagcgtttag aggctattaa aggctttact
    10201 gaattaggtt caggcttcaa gattgctatg cgagatttgt ctatacgagg agcaggtaat
    10261 attttagggg cttctcagag tggctttatt gattcggtcg gttttgaaat gtattctcag
    10321 ttattggaac aggctattgc tagcaagcaa ggaaaaacga ctgttcgcca aaaaggtaat
    10381 actgaaatca atcttcagat tgacgcctat ttgccagatg attacatatc agatgagcgt
    10441 caaaaaattg acatttacaa gcgtattcga gaaattcaat caagagaaga ttatctcaat
    10501 ttgcaggatg agctgataga tcgttttgga gagtatcctg atcaagttgc ctatttgtta
    10561 gagatagctc tgctaaaaca ttatatggac aatgcctttg cggaattagt tgaacgcaaa
    10621 aataatcagg tcattgttcg atttgaagta acttctttaa cttatttctt gactcaggat
    10681 tatttcgaag ccttatcgaa aacccatctt aaagctaaaa ttagtgaaca tcaggggaaa
    10741 atcgatatcg tctttgacgt tcgccatcaa aaagattata gaattttaga agaattgatg
    10801 ttatttggag aaaggcttag tgagataaaa atcagaaaaa acaattcagt ttttaaataa
    10861 taatttgaaa caacttttag actgaatagt attaatgaca atggaacgaa ctagctcttt
    10921 atacttttgt caaaaatcta agatctttgc tgcgaaatta ggatcttttc taccatttaa
    10981 aaaataaaaa tgataaaatg aagaggattg taggagaaat tatgagacta gataaatatc
    11041 taaaggtatc gcgccttatt aaacgtcgtt cagtagcaaa agaagttgcg gataagggac
    11101 gaattaaagt taatgggata cttgctaaaa gttcaacgaa tataaaacta aatgatcaca
    11161 ttgaaattag ttttggaaat aaattactga cagtaagagt cattgaaata aaagatagta
    11221 caaaaaaaga agatgctctt aagatgtatg agataatcag tgaaacaagg ataacattaa
    11281 atgaagaagc ctagtattgt tcaattaaat aatcattata ttaagaaaga gaatctcaaa
    11341 aaaaaatttg aagaagaaga atctcaaaaa agaaatcgtt ttatgggatg gatccttgta
    11401 agtatgatgt ttttatttat tttgccaact tataatcttg tcaaaagtta tgttgatttt
    11461 gaaaagcaaa atcaacaggt ggttaaatta aaaaaagagt ataatgaatt gtcaaagagg
    11521 acaaaaaaag aaaaacaatt agcagaacga ctaaaagatg ataattttgt caaaaaatat
    11581 gctagggcaa aatactattt atcgcgtgaa ggagaaatga tttatcctat tccaggacta
    11641 ttaccaaaat gatgatggac aatattgtaa aaaaaataga agcatttctt gctttttctg
    11701 ataaaaaatt agcagagctg caacaggaaa atcaaaaagt taaagaagaa agtcagtata
    11761 ttcaaaaaaa ctagaaagga gtcaatatga gaaaattatt agcggctatg ttaatgactt
    11821 tttttctgac tcctttacca gtgattagta cagaaaaaaa acttatattt tcaaaaaatg
    11881 ctgtttatca attgaaacaa gatgtcgttc aatcaacaca attctataat cagctaccct
    11941 ctaatccaaa tctttatcaa gaaacgtgtg cctataaaga cagtgattta actctaccag
    12001 caggaagatt aggtgtaaat caaccattac ttattaaatc gcttgttctt aacaaagaat
    12061 ctttaccggt ttttgagtta gctgatggta cctatgttga ggctaatcga caattgattt
    12121 atgacgatat tgtacttaat caagtagata tagatagcta tttttggaca caaaagaaac
    12181 ttaggcttta ttcagcccct tatgttttag gtacgcaaac aattccttct tctttttcat
    12241 ttgctcaaaa agttcatgcc actcaaatgg cacaaacaaa ccatggaact tattatctta
    12301 ttgatgataa gggctgggca tcacaagaag atctagttca atttgataac cgcatgttaa
    12361 aagtccagga aatgctctta caaaaatata ataacccaaa ttattcaatt tttgtaaagc
    12421 aactcaacac acaaacaagt gctggtatta atgctgataa aaaaatgtat gctgcaagta
    12481 tctcgaagtt agcaccactt tatattgttc aaaaacaatt acaaaaaaag aaattagcag
    12541 agaataaaac tttgacttat actaaagatg ttaatcattt ttatggagac tatgatccat
    12601 tgggaagtgg taaaattagt aaaatagctg ataataaaga ttatcgtgtt gaagacctac
    12661 tgaaagctgt agcacaacaa tcggataatg tagcaactaa tattttaggt tattatctat
    12721 gtcatcagta tgataaagct ttccgctcag agataaaagc tttatcaggt atcgattggg
    12781 atatggagca gcgcttatta acttctcgtt cagctgcaaa tatgatggaa gctatttatc
    12841 atcaaaaagg ccaaattatt tcttaccttt caaataccga atttgatcaa caacgtatca
    12901 caaaaaatat tactgttcca gttgcacata aaattggtga tgcttatgat tataaacatg
    12961 acgttgctat tgtttacggt aatactccat ttattttgtc tatttttaca aataaatcaa
    13021 cctatgaaga tattacggct attgcagatg acgtttatgg tattttaaaa tgatgaccta
    13081 tcaagaaatt tttaatgaaa taaaaaataa agcctacttt aaaaatcata gacatgtgtt
    13141 aatagccgta tctggtggag tagattcaat gaatttattg cactttttat acctgtttca
    13201 agacaaattg aaaattcgta ttggtattgc tcatgttaat cacaaacaaa gatcagaatc
    13261 agattcagaa gaagcttatt taaagtgttg ggctaaaaaa catgacatac ctatttatgt
    13321 ttctaatttt gaaggaatat tttcagaaaa agcagcacgt gattggcgct atgctttttt
    13381 taaaagtatt atgttaaaaa ataactattc agctttagta acagctcacc attcagatga
    13441 tcaagcagaa actattttga tgaggctaat tagaggaagc cgattgaggc acttgtcggg
    13501 tataaaaagc gtgcaaccat ttgccaatgg tcaacttata agaccttttt taactttctc
    13561 aaaaaaggac ttgccagaaa tttttcattt tgaagattct tcaaataggg aattatcatt
    13621 tttaagaaat agagttagaa ataattattt accattgtta aagcaggaaa atcctaggtt
    13681 cattcaggga ttaaatcaat tagcacttga aaatagctta ctttttcaag cttttaagga
    13741 gctaacaaat catattacta ccactgattt aacagaattt aatgagcaat
//
LOCUS       DAUGUF010000040        13535 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUGUF010000040 DAUGUF010000000
VERSION     DAUGUF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13535
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.040"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(46..315)
                     /locus_tag="VIB71_001472"
     CDS             complement(46..315)
                     /locus_tag="VIB71_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823199.1"
                     /translation="MKKPNRYPYSKSKFNGCIYQLHAASFKDEQYVEDLKSCGIHYQI
                     TKIGYFPDIFIKIDNLEQLQILIDKTGHDLILSKDQIWIYDDYME"
     gene            complement(312..497)
                     /locus_tag="VIB71_001473"
     CDS             complement(312..497)
                     /locus_tag="VIB71_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823200.1"
                     /translation="MTKKHVVRVYNKGITATYMVYDKNLFKEHEFATKREAMQFIRKL
                     ELANEKRSTEYFMREAE"
     gene            complement(490..771)
                     /locus_tag="VIB71_001474"
     CDS             complement(490..771)
                     /locus_tag="VIB71_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1599 domain-containing protein"
                     /protein_id="HEQ8823201.1"
                     /translation="MTYKINPESMQVAFDKNYQTFLDKNADYGNSFEKSLDDLGIVAG
                     VVRIGDKYNRVCNLIKNKQNVSESLSDTLNDMANYCMMLAVWLEGQKDD"
     gene            complement(896..1252)
                     /locus_tag="VIB71_001475"
     CDS             complement(896..1252)
                     /locus_tag="VIB71_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823202.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNIIITDPEEADRVYKSVKYYKNL
                     NRLPPPNVLDWFKQIYTTEEMITLIKQSYRLKQKKTDEDDEIYEKWMFKNYGDVKLVK
                     KVKRMDALAKAWEMGL"
     gene            complement(1236..1556)
                     /locus_tag="VIB71_001476"
     CDS             complement(1236..1556)
                     /locus_tag="VIB71_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEQ8823203.1"
                     /translation="MTTESLIQNQIRVGLSQAGHMVFRANVGKVKTADGRFFDTGLPK
                     GFCDLFGFKPDGQVFFIEVKNETGRVRPEQKKFMEVMASRGALVGVARSVEDALKIVN
                     DTSR"
     gene            complement(1553..1966)
                     /locus_tag="VIB71_001477"
     CDS             complement(1553..1966)
                     /locus_tag="VIB71_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823204.1"
                     /translation="MYDILKDYEDLPIPSESIYYHDWLIGNITSEEAKEHFYRSDHPK
                     GFLELSEDKQEKLLHWCKQLEKTKTYENGHTSYGLKHKFEYRKNGFYVTNGQFKGAML
                     LAGFKPKDKNKLNWVFAFSVKSLRKIIDTKRYVMV"
     gene            complement(2228..3703)
                     /locus_tag="VIB71_001478"
     CDS             complement(2228..3703)
                     /locus_tag="VIB71_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEQ8823205.1"
                     /translation="MDFEFYREKLNEEPGIEPGKPTTWSAIKSKLIAYRRDWLEEAGK
                     DVKNLSELAVAIGINKYLHVITLENGKVAIYDPDQGYYIKDYKFAYKLIHILQPTFNE
                     TKCRNVLFMLASMDRKYGAMDFEPEFQDVRRYVLVKNGIYDKYKRKLLPFDYRFINFS
                     TIETELIPNAPLPTIDGWDVESWLLDLMSGDKDLVKLLWQVVAASLNGNYSYRKSIWF
                     VGNGNDGKGTFQQMISNLVGFKNVAPLKLNQFSERFGLAIIEGKTVIIGDDVQAGIYV
                     DESSNFNSVVTGEPVSIEKKGENPYMAIFKKTVIQSTNGMPSFKNKSNGTYRRIIIIP
                     FKKTFSSKEDNWAIKDDYINRKEVLEYVLWKAINIDFDRFSEPKATQERMHAFKRDNN
                     TILAFIDDWFERFTSTVLPTRFLWWLYKEWCKDNGHTPLKQSTFENELSTNIPDGWVK
                     KKSRVAGKFFPSDEIPTEYGHFPWNNEKDANGSMQSYVKII"
     gene            complement(3693..4505)
                     /locus_tag="VIB71_001479"
     CDS             complement(3693..4505)
                     /locus_tag="VIB71_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEQ8823206.1"
                     /translation="MRGMIDYAIYYQQKGFSVIPISKDGKKPLVAFADKPAFTEHELR
                     LLWKDNPDANIALRTDSFFVIDIDVHNGVDGLKNLREWEHARLIPKTLQATTPSGGRH
                     IYLKKPQGVSMAQNIGFVDGVDLKAHVNNYVLVPPSNNAKGMYVWDKVHSPTSGEMTE
                     APLELITVLQELKPAYEYDASSFTSGDYQGSNKTAKLFETIVLGFGDTGGRNNSLAEF
                     VGGLLLRNVDVEIAYTLAKMANHKTVDPLNDKEFDRTFKSMCDKELRRRSGL"
     gene            complement(4508..4966)
                     /locus_tag="VIB71_001480"
     CDS             complement(4508..4966)
                     /locus_tag="VIB71_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HEQ8823207.1"
                     /translation="MFTIDYSKAKEFASITDGTYETFIEKAVQDATKNGADFINIHFR
                     IRKDFQQEFQNNIIFHRIFAKKEDGKYPEGVIHNLAKQAGIPEGTQFKSLDDYLNQLL
                     NKCLKITVKNETSEYNGNTYNNLNVKRIEKSDIPSMVNPVEEFKEDDLPF"
     gene            complement(4982..6217)
                     /locus_tag="VIB71_001481"
     CDS             complement(4982..6217)
                     /locus_tag="VIB71_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ8823208.1"
                     /translation="MVMAHIAKSATDKGNRVLFFSHRKEINEQVEKTFAVNGVNSNLL
                     TIGGVQSLVRKLDSLFQPEVILIDEAHHSKAKSYLKIIDYFKNAYVLMFTGTPVRLNG
                     DGFDDIADDLVVGKSVKWLQEHGNIANFKYYAPSMIDNSVLKKRGGEFTKDSVDQSMK
                     SVIYGDVIKHYEKLAKGKQAIVYTHSVEASHLVSDTFNQAGYQSQAVSGKTPKNEREE
                     AMRAFRDGDLKIMVNCELFTEGIDLPNVDVCIMLRPTQSLSLYLQFAMRPLNPRDGKT
                     AIIIDHVGNVERFGLPNMDREWRLDGETKQKQSAKIGEPTTRVCDNCYATYWSDTRIC
                     PECGHENELTKREIEEIKEAELQEISEQKQLKLKNRVSTYQTPDMCQTMDELTEYRKQ
                     HGYKPGWQYYIAKKLGILY"
     gene            complement(6313..7005)
                     /locus_tag="VIB71_001482"
     CDS             complement(6313..7005)
                     /locus_tag="VIB71_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ8823209.1"
                     /translation="MKITKATEITKTHNWRILIYGKPGNGKTYLTNYLQGKTLILDMD
                     HSSKTIAGNENIDIIQFDRTHPSDFMTEFLIELPELIKEYDNLVIDNITSWQSDWFIE
                     QGRKSKNGITNELQQYNMWTNYYLRVLTTIYSQPINIFVTAWESTQDLTLESGQIITQ
                     YIPDIRKQVLSQTLGLTDIVGRVQVNPKTGGHGILLQGSDGLYAKNRLDNRTVCKAEE
                     LFNFGDTVNETT"
     gene            complement(6992..7303)
                     /locus_tag="VIB71_001483"
     CDS             complement(6992..7303)
                     /locus_tag="VIB71_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823210.1"
                     /translation="MGSEGLRLRIYINKHKKMIIAPDYNDRYGGISNTTIQLRTGKLT
                     EAIEQEVGEAILDIIKKYEPIFDTPIIDDLFREKEQAIRKMVDYDTALTEMVEVEDEN
                     Y"
     gene            complement(7413..7595)
                     /locus_tag="VIB71_001484"
     CDS             complement(7413..7595)
                     /locus_tag="VIB71_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823211.1"
                     /translation="MEKLTLKKEKENTATLPFFVGIDLHAQIKEISTETGIPMRRIIE
                     RMIRFSLDNLEIMEGD"
     gene            complement(7583..7795)
                     /locus_tag="VIB71_001485"
     CDS             complement(7583..7795)
                     /locus_tag="VIB71_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823212.1"
                     /translation="MDQYLINDNEFLRDENTRLNKEFSELNHAVAKANLLDVIIEDGY
                     ILQSTLDKCTAKLDEIDQKELKTWKN"
     gene            complement(7805..7945)
                     /locus_tag="VIB71_001486"
     CDS             complement(7805..7945)
                     /locus_tag="VIB71_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823213.1"
                     /translation="MKLLDFIFAKPKKQEEKPKWTIENNGWEANTRRYNQKHGLPAKQ
                     IW"
     gene            complement(7942..8187)
                     /locus_tag="VIB71_001487"
     CDS             complement(7942..8187)
                     /locus_tag="VIB71_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823214.1"
                     /translation="MEIVHIKDIVTEPYSADDETLGKIFGYTKRQMQDRRYEMVKIPY
                     FSKYLLEQGGRVTIDGMREYLFYRKSIEWEKDKEKYL"
     gene            complement(8260..8445)
                     /locus_tag="VIB71_001488"
     CDS             complement(8260..8445)
                     /locus_tag="VIB71_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8823215.1"
                     /translation="MWGKLSKILSERGMTMYQLAKLSGVNKSHFSDLKSGKIKNLSWP
                     NMVKISDALGVSLDEFK"
     gene            8590..8820
                     /locus_tag="VIB71_001489"
     CDS             8590..8820
                     /locus_tag="VIB71_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823216.1"
                     /translation="MEIFSYPENAKELYEKHKKAIEQACEPIATMLALNNPELTDLAN
                     EALELYARTIYNACVDASIIIRNREYQHYRDQ"
     gene            8983..9192
                     /locus_tag="VIB71_001490"
     CDS             8983..9192
                     /locus_tag="VIB71_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823217.1"
                     /translation="MNLEELTPLLNSIDDFETVILHSLVGDFVIDHWIEPNRKNETLI
                     FMHNDQTTELKLSAILGTSTIPKSL"
     gene            complement(9438..9644)
                     /locus_tag="VIB71_001491"
     CDS             complement(9438..9644)
                     /locus_tag="VIB71_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8823218.1"
                     /translation="MQENAFEQLIDDSGIKKKVIATKMGFTRSGFYQKRKKPKKSFDA
                     SEVAMLADILGVDPGKVLEAILIS"
     gene            9737..10378
                     /locus_tag="VIB71_001492"
     CDS             9737..10378
                     /locus_tag="VIB71_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823219.1"
                     /translation="MNFFNFLLCVFKFTSEYLIKNWIALIALFLSYSNYRRNNLQVEL
                     IAAPVSDWILSVILDNGESIYNPNGTLRANIKIINPSNVDVSYFDLIVFDKNRKYQHY
                     YQKQNNIINDLTGREAIAAVQPDGNTILIEVPEADCGVLKAHSMTRMDLIIQTSEITD
                     RLFVAFKVAKKKKLFKANKAGYVNSPYQSFSASFPVELSKKPHYEDILKDLHE"
     gene            complement(10477..10635)
                     /locus_tag="VIB71_001493"
     CDS             complement(10477..10635)
                     /locus_tag="VIB71_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823220.1"
                     /translation="MNWKKLMFGDLEYTFASRDGKEKTSIEFEGGVLPALLVLCGITW
                     LIAWFITK"
     gene            11022..11771
                     /locus_tag="VIB71_001494"
     CDS             11022..11771
                     /locus_tag="VIB71_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8823221.1"
                     /translation="MASTIAFPAMVKELRLGKNLTMEQLAEELGKTKSTISKWEKGTR
                     SPKIYEIEEIAKFFGVEPKKMMFGDNPTSINPQVELIPSTLQKINSTSSQLEHSRQII
                     VLDTAETLLEQQKEIKNNEDTIAELFSYNYYDHAASAGTGQYLNDVQVEKIELPVDYD
                     ADFVIPVYGDSMEPKYHSGDYVFIKLSVELADGDIGVFEYYGDAYIKQLLINDEGAFL
                     HSLNGKYEDIPVDRDSDFRIIGEVVGSYSEK"
     gene            11797..12339
                     /locus_tag="VIB71_001495"
     CDS             11797..12339
                     /locus_tag="VIB71_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEQ8823222.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            12490..>13535
                     /locus_tag="VIB71_001496"
     CDS             12490..>13535
                     /locus_tag="VIB71_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEQ8823223.1"
                     /translation="MRKVAIYSRVSTINQAEEGYSIQGQIEALTKYCEAMEWKIYKNY
                     SDAGFSGGKLERPAITELIEDGKNNKFDTILVYKLDRLSRNVKDTLYLVKDVFTANNI
                     HFVSLKENIDTSSAMGNLFLTLLSAIAEFEREQIKERMQFGVMNRAKSGKTTAWKTPP
                     YGYRYNKDEKTLSVNELEAANVRQMFDMIISGCSIMSITNYARDNFVGNTWTHVKVKR
                     ILENETYKGLVKYREQTFSGDHQAIIDEKTYNKAQIALAHRTDTKTNTRPFQGKYMLS
                     HIAKCGYCGAPLKVCTGRAKNDGTRRQTYVCVNKTESLARRSVNNYNNQKICNTGRYE
                     KNTSKNMLLMFFIN"
BASE COUNT         3964 a         2592 c         2266 g         4713 t
ORIGIN      
        1 gatcttttta ttaaatgctc taaattttgg tatcattatt actcctcatt ccatatagtc
       61 atcataaatc caaatttggt ctttactaag tattaaatcg tgtcctgttt tatctattaa
      121 tatttgtaat tgttcgagat tatcaatttt tataaaaata tcaggaaaat aaccaatttt
      181 tgtaatttga taatgtatgc cgcatgattt taaatcttca acatattgtt catctttaaa
      241 gctggctgca tgcaactggt aaatacaacc attaaatttt gatttactgt atggataacg
      301 atttggtttc ttcattccgc ttccctcatg aaatattccg tcgatcgctt ctcatttgct
      361 aactctagtt ttctgataaa ctgcatcgct tctctttttg ttgcgaactc atgctcctta
      421 aacaggtttt tgtcataaac catgtaagtc gctgtaatgc ctttgttgta aactctcaca
      481 acgtgttttt tagtcatctt tttgtccctc caaccaaacc gctaacatca tgcaataatt
      541 agccatgtcg tttaacgtgt ctgataggct ctctgagacg ttttgtttat ttttgataag
      601 attacacacc cgattgtatt tatcgccgat tctgaccact cctgcgacaa tcccgaggtc
      661 gtcaagcgac ttttcaaacg agtttccgta atctgcgttt ttatctaaaa atgtttgata
      721 gtttttatca aaagctactt gcattgattc tggattaatt ttatatgtca tccttttacc
      781 tctctcaaaa aatctataat caatttacac tcgctcttat ttacatcata aggcaacaca
      841 ctgtcgtaag atttaggtgt gtatttaata tctttattaa actgcctgcg tcttttcata
      901 gtcccatctc ccatgcttta gctaatgcat ccatacgttt gacttttttg acaagcttaa
      961 catcaccata atttttaaac atccactttt cgtagatttc gtcatcctcg tccgtctttt
     1021 tttgtttaag acggtaagac tgcttgatta acgttatcat ttcctcagtc gtgtagattt
     1081 gtttaaacca atctaatacg ttaggaggtg gcaatctatt aaggttttta tagtatttga
     1141 cagatttata cactctgtca gcttcttctg gatccgtgat gataatgttg tcgtctaaaa
     1201 atgctttgat tgacggctcc atttgtttgt aaaaatcatc tactagtgtc attgactatt
     1261 tttaaggcat cttccacaga tctagccact cctacaagcg ctcccctaga tgccatgacc
     1321 tccataaatt ttttctgttc aggtcttact cgacctgttt catttttaac ttcgataaaa
     1381 aacacttgcc cgtctggttt aaatccaaac aagtcacaaa aaccttttgg taaacctgta
     1441 tcaaaaaatc tgccgtctgc tgttttaact ttaccaacgt tggctctaaa aaccatatgg
     1501 cccgcttgtg ataatccaac acgaatttgg ttttgaatta atgattctgt tgtcatacca
     1561 tcacatacct ttttgtatcg ataatttttc ttagcgattt tacactaaaa gcaaataccc
     1621 aattcaattt gtttttgtct ttaggtttaa aaccagcaag caacatagct cctttgaatt
     1681 gaccgtttgt aacataaaaa ccatttttac ggtattcaaa cttatgcttt aatccataag
     1741 aggtatgccc attttcataa gtttttgttt tttctaactg cttacaccag tgcagcaatt
     1801 tttcttgttt gtcttcactt agttctaaaa aacctttagg atgatcactg cgataaaaat
     1861 gctctttagc ttcttcgcta gtgatatttc caattaacca gtcgtgatag taaatcgatt
     1921 cagaaggaat cggaaggtct tcgtaatctt ttaaaatatc gtacatactt tctccttttt
     1981 tgattttgtt cccaccaatg ttccaacagg gtggaacgca ccaattcctt gcggctcaag
     2041 ggattagacc atttctgttc catgttccgc cattttttgc ttttctctct atatatttat
     2101 attatttatt tttttattaa tattaagaaa aagatggaac atggaacaga agtctattaa
     2161 acccagtaat accaaagggt ttcgctgttc catgtcatgg aacaaggatg gaacaaagac
     2221 ggaacattta tataatcttc acataagatt gcatacttcc attagcgtct ttttcattat
     2281 tccaaggaaa gtggccatat tctgttggta tttcgtcaga cgggaagaat tttcctgcga
     2341 ctctagattt tttcttaacc cagccatcag ggatattggt tgacaattca ttttcaaaag
     2401 ttgattgctt aagcggtgtg tgcccattat ctttgcacca ctctttatac aaccaccata
     2461 agaatctagt agggagcaca gtagaagtaa aacgctcaaa ccaatcatct ataaaagcga
     2521 gtatcgtgtt gttgtctcgc ttaaaagcat gcattctttc ttgtgtcgct ttcggctcac
     2581 taaacctatc aaaatctata ttgatagctt tccaaaggac gtattcaagc acttctttac
     2641 gattaatgta atcatcttta atggcccagt tatcttcctt tgatgagaat gtctttttaa
     2701 acgggatgat gataatgcgg cgataagtac catttgattt atttttaaac gatggcatcc
     2761 cgtttgttga ttgtatgacg gtttttttaa aaatcgccat gtaagggttc tcaccttttt
     2821 tctcgatgct cacaggctca ccagtcacga cagagttaaa gttactactt tcgtccacat
     2881 agataccagc ttgaacatca tctccgataa ttaccgtttt cccctcaata atcgcaagac
     2941 cgaagcgttc tgaaaattga tttaatttta gaggagcgac atttttaaaa ccaaccagat
     3001 tgctgatcat ctgttgaaac gtccctttac catcgttacc attacctacg aaccagattg
     3061 atttacgata agagtagtta ccgtttaagg atgctgccac gacttgccat aataacttga
     3121 cgaggtcctt atctccgctc attaaatcta ataaccatga ctccacgtcc caaccgtcaa
     3181 tggttgggag aggagcgttt ggaataagtt ctgtttcgat agtgctgaaa ttaataaatc
     3241 ggtaatcaaa aggcaataat ttgcgtttgt atttgtcgta aataccattt ttaactagta
     3301 cataccgtct cacgtcttgg aattctggtt cgaagtccat tgccccatat ttcctatcca
     3361 tactcgctaa cataaacaac acgttacggc attttgtctc attaaacgta ggttgtagaa
     3421 tatggattaa tttataagcg aatttatagt ccttgatgta atatccttgg tctggatcgt
     3481 agatagctac tttcccgttt tctaaggtaa taacatgcag gtacttattt attccgatag
     3541 caacagctag ttctgataaa tttttaacat ctttcccagc ttcttcaagc cagtctcttc
     3601 gatacgctat caatttggat ttgatagcag accatgttgt gggtttacct ggttcaatgc
     3661 caggttcctc atttaatttt tctctgtaaa attcaaagtc cacttctcct cctcaattcc
     3721 ttgtcacaca tacttttaaa agtacgatca aactccttat catttaaagg gtcaactgtt
     3781 ttgtgattag ccattttagc taatgtgtat gctatttcaa catctacatt tctaagcaat
     3841 agaccaccta caaattcagc gagactgttg tttctgccac ctgtatcacc aaaaccaagg
     3901 acaatcgtct caaataattt agctgtttta ttgctacctt ggtaatctcc agatgtaaaa
     3961 ctactagcat catactcgta agcaggcttt aattcttgca atacagttat caactcaaga
     4021 ggcgcttcgg tcatttcgcc agaggttggc gaatgcacct tatcccacac atacatgcct
     4081 ttggcattgt ttgatggtgg taccaacaca taattgttaa catgagcttt taagtccaca
     4141 ccatcgacaa aaccgatatt ttgcgccatg gaaacgcctt gtggtttttt aaggtagata
     4201 tgccttcctc cactaggcgt ggttgcttgc aaggtttttg gtatcaacct tgcatgctcc
     4261 cattctctaa ggtttttcag accgtcaacg ccattgtgga catcaatatc aatgacaaaa
     4321 aacgaatctg ttcttagagc aatattggca tctggattat ccttccacaa aagccgcaac
     4381 tcatgctccg taaaagctgg tttatccgca aaagcgacta atggtttttt accatccttt
     4441 gaaatcggaa taactgaaaa tcccttttgt tgataataga ttgcgtaatc tatcatccct
     4501 ctcataatta gaatggaaga tcgtcttctt taaattcttc cacagggtta accatagatg
     4561 gaatatcgga cttttcgata cgtttcacat ttaagttgtt gtaagtattt ccgttatatt
     4621 cggatgtttc atttttaacg gtaattttga gacacttgtt aagtagttga tttaagtaat
     4681 catccaggga cttaaactgt gtaccctcag gaatacctgc ttgcttagcg agattatgaa
     4741 tgaccccttc tggatatttc ccgtcttctt ttttggcaaa aatacggtgg aagataatgt
     4801 tattttgaaa ctcttgttgg aagtctttgc gaattctgaa gtgaatgttg ataaagtctg
     4861 cgccattttt agttgcgtct tggaccgctt tttcaataaa tgtttcgtaa gttccgtcag
     4921 taattgatgc aaattccttt gcttttgagt aatcgattgt aaacataatg tatttctcct
     4981 tttaatataa aattcctagt tttttagcga tgtaatactg ccaacctggc ttgtatccat
     5041 gttgttttcg gtattctgtt agttcgtcca tcgtctggca catgtcaggt gtctgatagg
     5101 tactaactct attttttagt tttagttgtt tttgttcaga tatttcttgt aattcagctt
     5161 ctttgatttc ttcgatttca cgtttggtca actcgttttc gtgtccacat tctggacaga
     5221 tacgagtatc ggaccaatag gtggcataac agttatcgca aactcttgtg gtaggctcac
     5281 caatcttagc ggattgcttt tgtttagtct ctccatctaa acgccattct ctatccatgt
     5341 taggtaaacc aaaacgctcc acattgccaa cgtgatcaat aataatggct gttttcccat
     5401 ctcttggatt taacggtcgc attgcaaatt gcaaatatag cgatagcgat tgtgttggtc
     5461 tcaacataat gcaaacatca acatttggca ggtctatccc ttctgtaaac aattcacagt
     5521 taaccatgat ttttaaatca ccatctctaa atgctcgcat agcttcttcc cgttcgttct
     5581 taggcgtttt tccgctcact gcttgtgatt ggtaccctgc ttgattaaag gtgtcagaaa
     5641 ccaaatgaga ggcttctacg ctgtgcgtat aaacgatagc ttgctttcct tttgctagct
     5701 tttcatagtg tttaataaca tcaccataga taaccgattt catggattga tcaacagaat
     5761 ccttagtaaa ctctccacct ctttttttaa ggacagaatt atcaatcatg gacggtgcgt
     5821 agtatttaaa gttagctata ttaccgtgtt cttgcagcca tttgacagat tttccaacta
     5881 ccaaatcatc agcaatatca tcaaatccat ctccatttaa cctgactggt gtcccagtga
     5941 acattaatac ataagcattt ttaaaatagt cgatgatttt taagtaagac ttggccttac
     6001 tgtgatgagc ctcgtcaatc aaaattactt ctggttgaaa gaggctgtct agtttcctaa
     6061 ctagcgattg cacgccgccg atagttaaca ggtttgagtt aactccattt actgcaaatg
     6121 tcttttctac ctgttcattg atttcttttc tatggctaaa aaacaatact ctgtttcctt
     6181 tatccgtagc gcttttagcg atatgggcca ttaccaccgt tttcccgctt ctagggaggc
     6241 gactggacga ttattctttt atttccagtc gctaatgacc tcctaatatc tgttaataat
     6301 tcttcttggt aatcacgtag tttcatttac tgtgtctccg aaattgaata attcttctgc
     6361 tttacaaact gtcctattat caagtctgtt ttttgcatat agtccgtcac tgccttgcag
     6421 cagaattcca tgtccgcctg ttttaggatt tacttggaca cgaccgacaa tatctgttaa
     6481 accaagtgtt tgacttaata cttgcttacg gatgtctggg atgtattgcg tgataatttg
     6541 tccgctctca agcgttaaat cttgcgtcga ttcccaagcc gtcacaaaaa tattaatagg
     6601 ttggctgtaa atagtagtca atactcttaa atagtaattg gtccacatgt tgtattgttg
     6661 caattcgttt gtgattccgt ttttggattt acgaccctgc tcaataaacc agtctgattg
     6721 ccaacttgtg atgttatcaa tgactaaatt gtcatattct ttgataagtt ctggtaattc
     6781 tatcaagaat tcagtcataa agtcgcttgg atgcgtcctg tcaaattgaa taatatcaat
     6841 gttttcattt ccggcaatcg ttttagatga gtgatccatg tctaaaatca gtgtcttgcc
     6901 ttgtaagtaa ttagttaagt aagttttccc gtttcctggt tttccataga ttaatatgcg
     6961 ccaattatga gtttttgtaa tttctgtcgc tttagtaatt ttcatcttcc acctccacca
     7021 tctcagttaa ggcagtgtca taatcaacca tttttctgat tgcttgttcc ttttctctaa
     7081 ataaatcatc aattattggg gtgtcaaaaa taggttcgta tttttttata atatctaaaa
     7141 tcgcttcgcc gacttcttgt tctatggctt ctgttaattt tccagttctt aattggatag
     7201 ttgtatttga tataccaccg tatctatcat tgtaatctgg tgcgataatc atttttttat
     7261 gtttgttaat gtagattctc aatcgtaagc cctcgcttcc catgtgattt gcggatcggg
     7321 ttctttacag caagggcatt ccaagtcctt gtatgctgat atgtttgacc attttttgcc
     7381 gcaattttcg caataatatt caaagctata cattaatccc cttccatgat ttctaggtta
     7441 tcaagagaaa acctaatcat tctttcaata attcttctca ttgggatacc tgtttctgtc
     7501 gagatttctt tgatttgggc gtgtaaatca atccctacaa aaaacggtaa tgttgcagta
     7561 ttttcttttt ctttttttaa agttagtttt tccatgtttt caactccttc tgatcaatct
     7621 catcaagctt agcagtacat ttgtccagcg tgctttgcag gatatatcca tcctcgatga
     7681 tgacatctaa taaatttgct ttagcaaccg catgatttaa ctcgctaaac tctttgttga
     7741 gtcgtgtgtt ttcgtctctt aaaaattcgt tatcattgat taggtattga tccattcttt
     7801 cctcctacca aatttgttta gcaggcaaac cgtgtttttg gttatatcta cgtgtattgg
     7861 cttcccaacc gttgttttca atcgtccatt ttggtttttc ttcctgtttt tttggtttcg
     7921 caaaaataaa atctaatagt ttcacagata cttctcctta tctttttccc attctattga
     7981 tttgcgataa aacaaatatt ctcgcatccc gtcaatagtt actcttccac cttgttccaa
     8041 aaggtacttt gaaaaatatg gaatctttac catctcataa cgcctgtctt gcatttgacg
     8101 cttagtatat ccaaaaattt tacctaacgt ctcgtcatct gcgctataag gttcggtgac
     8161 tatgtctttt atgtgtacta tttccattct gtccctttct atgttataat taagtaaatt
     8221 aatctagttt tgagtccgat tcccgtcggg ctttttttgt tatttaaatt cgtctaagct
     8281 gacacctaaa gcgtcagaaa ttttgaccat gttaggccac gacaaatttt ttatttttcc
     8341 gctttttaag tcgctaaaat gacttttatt aactccagaa agtttcgcta attgatacat
     8401 agtcatacct ctttctgata aaatttttga taatttaccc cacattaccc actcaccaaa
     8461 acacaatatg tagttgttta taagttatcc acaactatag gttgtgtttt cctttctatt
     8521 ctgatataat ttatttgaat atgacctctc accgttgtat tcaaaaatta tggaaaggag
     8581 ggaaggagta tggagatatt tagctatcca gaaaatgcca aggaactgta cgagaagcat
     8641 aagaaagcaa tagaacaagc ttgcgaacca atcgctacca tgttagcttt aaataatcct
     8701 gaattaacag acctagcaaa cgaagcttta gaactctacg caaggacaat ttacaatgca
     8761 tgcgttgacg catctattat cattcgaaat cgcgagtatc aacattatcg cgaccaataa
     8821 gttctgattg ccgattggta aaaaattctg cttttatcat gctagcatct attttgaaat
     8881 aggtgctttt ttcttttctg ctatacggat atcgttttgg tctcatgtgg cttcctttct
     8941 gttgtataat gtagttatcc tattaggaag gagggtaact aaatgaattt agaagaatta
     9001 actcctctat tgaatagtat tgatgatttt gaaactgtta ttttacatag tcttgtcgga
     9061 gactttgtta ttgatcattg gattgagcct aatcgcaaaa atgaaactct cattttcatg
     9121 cacaatgacc aaacaacaga attaaaatta tcagctattc tcggaacttc cactattcct
     9181 aagtccctct agcaaattgc ggactttttc ggaacgtttg cctgcatatt ttgattttcc
     9241 gagtctccaa cttagtaggc gatgttcctc ttctgataag taacctgctc tttgtagcag
     9301 gttttttgct accttccatg gaatcactac atctacttca tccatgttta ttaccatttc
     9361 ttcaagttct tctagtttgt tttctatttc gttcatatgt gtcctttcta aattttgtgt
     9421 tatttttgtc aacttttcta tgaaattaaa atggcttcta ggacttttcc ggggtctacc
     9481 cctaaaatat cagctagcat tgccacttct gacgcatcaa atgatttttt tggtttttta
     9541 cgtttctgat aaaatccaga gcgtgtaaaa cccattttag tcgcgataac tttcttttta
     9601 attccgctat catcaatcaa ttgctcgaaa gcattttcct gcattccccc accccctttc
     9661 taatttggaa ttatccaaaa caacatagct ttaaaatttt ctgtggtata atttaaataa
     9721 aaattgtgag gttgaaatga atttttttaa ttttttattg tgtgttttta agtttacaag
     9781 tgaatatcta ataaaaaatt ggatagcttt aatagctctg tttctatctt attcaaacta
     9841 ccgaagaaat aacttacaag tcgagttaat tgctgctcct gtttcagatt ggattttgag
     9901 cgttatttta gacaacggtg aaagcatata taatccaaat ggtacattaa gagctaacat
     9961 taaaatcatc aatccttcta atgttgatgt aagctacttc gacttgattg tttttgataa
    10021 aaacagaaaa tatcagcatt attaccaaaa gcaaaataat ataattaacg atttaacagg
    10081 tagagaggct atagccgcag tacagcctga tggcaataca atccttatcg aggttccaga
    10141 ggcagattgt ggagtattaa aagcccacag tatgacaagg atggatttaa tcatacaaac
    10201 gtctgaaatc acagatagac tctttgttgc ttttaaagta gctaaaaaga aaaaactatt
    10261 taaagctaat aaagcaggat atgttaattc accttatcaa tcattttctg cgtcattccc
    10321 tgtggaatta tcaaaaaaac cgcactacga ggatatccta aaagatttgc atgagtgaga
    10381 gcagattttc ttgtgtgaaa tatcttggaa gaacctagta caccgtattt aattttttcc
    10441 atgccttccc tcctttccac tccttttggg gagtttttat tttgtaataa accaagcaat
    10501 cagccaagtg ataccgcata gcactaacag cgctggtaat acgccgcctt caaattcgat
    10561 gcttgttttt tctttgccgt cacgactggc aaacgtgtat tctagatcgc caaacattag
    10621 ttttttccaa ttcatgcaac ctctcctttc attcttgcgg agatacagcc aatgtgctaa
    10681 actaaactta ccccgttagg ggagagggct tcttagccct cttgatattg tcaccactct
    10741 attgtagtga accctaagct taaaccaaag aatcttgatt tcgacttcta gttctttgtg
    10801 tttaggcttt ttgtttagcc tagatttcat cagctgtacc tcctttcgtt ttgcttaatt
    10861 ccttaagctt gattatagtt taacactgtg tttccttttt gtcaactatt ttgtgttaaa
    10921 aaagtcaact tttttgaatt tgattttttg ctatttttgt tgacattttg taaacatgta
    10981 attataatgt agataattaa gctataaaaa ggagaattta tatggcttcc actatcgcat
    11041 ttccggcaat ggtcaaagaa cttaggcttg gtaagaattt gactatggaa cagttagcag
    11101 aagaacttgg aaaaacaaag tcaacaatat caaaatggga aaaagggacg cgttctccta
    11161 aaatatatga gattgaagag atagcaaaat tcttcggtgt agagcctaag aaaatgatgt
    11221 ttggagataa tcccacttcg atcaatcccc aagtcgaact tatcccatct actctacaaa
    11281 aaataaactc tacttcttct caactagaac acagtagaca gataattgtt ttagatacag
    11341 ctgagacttt attggaacaa cagaaagaaa ttaaaaacaa cgaagatact attgccgaat
    11401 tattttctta caactactac gaccacgcag cttcagctgg tacaggtcag tatctaaatg
    11461 atgtacaagt agaaaaaatt gagttaccag ttgattatga cgcagacttt gttatccctg
    11521 tttatggtga ttccatggaa ccgaagtatc actctgggga ttatgtgttt attaaactat
    11581 ccgtagagct cgcagatggc gatataggcg tctttgagta ttatggtgac gcttatatca
    11641 aacagctgct tataaatgac gagggggcat ttctgcacag tttaaatggc aagtatgaag
    11701 atatacccgt agatagagat agcgacttta gaattattgg tgaagttgtg gggagttatt
    11761 ctgaaaaata agaatatttt tataaggagt tttattatga atttagatac tgttttgcaa
    11821 caaatgaagg aatgtggggc ttacgacact tggggaacaa agaaagaagt aaaagctttg
    11881 ccagaaattt tgtcagatga cgaaattatc caatacgcaa catctgggtt tgtaaacggc
    11941 aatactgtcc ttgttgtatt gacccaaaaa cgaattttat ttatcgataa gggaatgtta
    12001 tatggaatta gatcgacaga aattcctctt gatatggtta atagcgtctc atactctaaa
    12061 ggtttaattc ttggcgcaat agctgttatg aacggagcca caaaaattga aatatctaat
    12121 attgccaagg acacttgccc tgtacttacc gaaaaaataa aagattgtgt agaacaatac
    12181 aaatataatc tgtaccaaca tcaatcgcct cagaaaacag caactgtagg ctcggaagat
    12241 gccgttgctg aaatccgtaa gtttaaaaaa ctttatgatg aaggcatcct tacagaggaa
    12301 gagtttatag ctaagaaaaa aataatttta gggatttaag gtgtaaagtt aaccgttaaa
    12361 aaataaaaaa gccccacgct ctcaaacttt ggcgagtctg agcgtgaggc gaattctagt
    12421 atagtaaaaa cctgctttaa gtaggtctct ttactgtact cattttaaca aaaaatgagg
    12481 taaaaaacaa tgagaaaagt agctatttac tctagagtat caacaataaa tcaagccgaa
    12541 gaaggatatt ccattcaagg acagattgaa gctttaacaa agtattgtga ggcaatggaa
    12601 tggaaaattt acaaaaacta ctctgatgca ggtttttcag gcggtaaact tgaacgaccg
    12661 gcaataacag aattgattga agacggtaaa aacaataaat ttgatactat tttagtctat
    12721 aaactagaca ggctatcaag aaatgtaaaa gacacacttt acttagtcaa agatgtattt
    12781 actgctaaca atatccattt tgtcagctta aaagaaaata tcgacacttc ttcagcaatg
    12841 ggaaatctct ttctcactct cttgtcagct attgcagagt ttgaaagaga acagattaaa
    12901 gagcgaatgc agtttggtgt tatgaataga gcaaaatctg gaaaaacaac ggcttggaaa
    12961 acaccacctt atggatatag atacaacaaa gacgaaaaaa cattgtcggt caacgagtta
    13021 gaggctgcta atgtcaggca gatgtttgac atgataatct ctggctgctc aatcatgtca
    13081 attacaaatt acgcgagaga caatttcgtc gggaatacgt ggacacatgt aaaagtaaaa
    13141 agaatattag aaaacgaaac atataaagga ttagtgaagt atagggaaca aactttctca
    13201 ggtgatcatc aagccattat cgacgaaaaa acatataata aagcgcaaat agctttagca
    13261 cataggacag atacgaaaac aaatactaga ccttttcaag ggaaatatat gctttctcac
    13321 atagcaaaat gcggttattg tggtgcccct ttaaaagtat gcacaggaag agctaagaac
    13381 gatggtacga gaaggcaaac ttacgtttgt gttaataaaa cagaaagttt ggctagacga
    13441 agtgttaata attataataa ccaaaagatt tgtaacactg gtcgatatga aaaaaacaca
    13501 tcgaaaaata tgttattgat gttctttata aactt
//
LOCUS       DAUGUF010000041        13525 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUGUF010000041 DAUGUF010000000
VERSION     DAUGUF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13525
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.041"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(93..878)
                     /locus_tag="VIB71_001497"
     CDS             complement(93..878)
                     /locus_tag="VIB71_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823224.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKVDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSAGSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(888..1586)
                     /locus_tag="VIB71_001498"
     CDS             complement(888..1586)
                     /locus_tag="VIB71_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823225.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(1586..1957)
                     /locus_tag="VIB71_001499"
     CDS             complement(1586..1957)
                     /locus_tag="VIB71_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8823226.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     SVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            2142..5252
                     /locus_tag="VIB71_001500"
     CDS             2142..5252
                     /locus_tag="VIB71_001500"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEQ8823227.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIASILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            5332..6345
                     /gene="pfkA"
                     /locus_tag="VIB71_001501"
     CDS             5332..6345
                     /gene="pfkA"
                     /locus_tag="VIB71_001501"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEQ8823228.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            6408..7910
                     /gene="pyk"
                     /locus_tag="VIB71_001502"
     CDS             6408..7910
                     /gene="pyk"
                     /locus_tag="VIB71_001502"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ8823229.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            8128..8685
                     /gene="lepB"
                     /locus_tag="VIB71_001503"
     CDS             8128..8685
                     /gene="lepB"
                     /locus_tag="VIB71_001503"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ8823230.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            8861..10675
                     /gene="glmS"
                     /locus_tag="VIB71_001504"
     CDS             8861..10675
                     /gene="glmS"
                     /locus_tag="VIB71_001504"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEQ8823231.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANAHQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVIVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVSSHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHSF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            10857..11192
                     /locus_tag="VIB71_001505"
     CDS             10857..11192
                     /locus_tag="VIB71_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEQ8823232.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            11299..11940
                     /locus_tag="VIB71_001506"
     CDS             11299..11940
                     /locus_tag="VIB71_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ8823233.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGTILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            11950..12579
                     /locus_tag="VIB71_001507"
     CDS             11950..12579
                     /locus_tag="VIB71_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823234.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIAPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            12595..13431
                     /locus_tag="VIB71_001508"
     CDS             12595..13431
                     /locus_tag="VIB71_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ8823235.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         4258 a         2232 c         2808 g         4227 t
ORIGIN      
        1 gaagacggtt tttttattta ctatgaacac tgaaaaaaac tttcttttaa actatagtgt
       61 gtcatagttt aaaagaaagt cttaacgctt acttactgta ggttgagttt atttttgata
      121 ataaaattag tggcgaggta aaacattatc atttcaataa attgttccaa aataagaaga
      181 taaattgttt tttgctcagt aaatgggaaa ctaccggcac ttgtattaat attaaagatg
      241 tgactgtgaa catatgttgc agcaacgcta atcagaataa ctaatataaa atatgcaata
      301 aaggccatca agcctcgccg attggaaaaa agttgaccta tagaaatgga aagataaatt
      361 aataagatac tcgtaaatgt tgataatagg acataggcta gtacagttag catattgatg
      421 aaataatcca ccttaaaact attaaagaat ccttctaata gttcgttgat gttaaacatt
      481 ggtacaatta caatagcgat agcaaatgca aggatgatag tattgaaaac actgcaaata
      541 aaagaagcta gtagttttga taaaataatt tgatgcgaat tgacgggtaa agtcaacgtt
      601 aagtatcctt cccgtccaaa aacacttttg ctaaaacgtt tgataatgat aagtaatgtt
      661 gataagaggg aaccagcgat cagggagcca aaagttaaac ctaatgtcag aggcaacatc
      721 ttattggtta gtactccaaa tagtccatca ctattacttt gagcaaacag ttttatcgta
      781 aatgacaaaa tggcagcgat ggcaataacg aaagcattaa gcgcaaagta ccattttcca
      841 atagatctaa attcgtattt taataatttt ccaaacatga tatcctccta aaccttataa
      901 gtttccctaa agagggaatc aatggattgc tggtattctt gtcttagatc atcagcattg
      961 ccagataaga aaagtcttcc ttgtttcaag aaaatgactt cgtcaaggat aggttcaatg
     1021 tccgaaatca agtgggttga gataataaca gaagcatttt cacaataact attaatgatg
     1081 gtttttagga tgtagtctct tgcagcaggg tcaactccac caataggttc atcaagtaca
     1141 tagagtctgg ctttacgact catcacaaga attaattgta ctttttcttt gtttcctttg
     1201 gatagagttt tgaagcggtc ttcagggtct agttctaaat ctcttagaag gcttgttgct
     1261 ttggatttgt caaagtcgct gtaaaaatca ctaaagaact ccaacatgtc cttaattctc
     1321 atattttcat tgagataagt agtatctggt aaataagaaa taattttttt tgtctcaaca
     1381 cagggacggt agccatcaat gacaatttct cctttatttg gttgtaaaag gccattaatg
     1441 agtttaatta aagttgtttt accacttcca tttggaccta ataatccgat aattttaccg
     1501 ttcgggatag taatggttaa gtcatcaata gctttttttt cacggtaaga ttttgaaaca
     1561 tgatgtagtt gcaataggtg tgccattatt gtgaatcctc ctttaaaaag ctcgtcaaaa
     1621 cagggataat ctcagtgtga ctaaatccca tttttgtcat attggtgata aatgattcta
     1681 attcactaat tgctaactct cgtcttttac gagcaattaa tttttgatcg tcagttacaa
     1741 aacggccagc agtacgttgc gaataaacca ttccttcccg ttcaagttct gtaaacgctc
     1801 gttgcatggt gttaggatta acacttgcga tttctgcata ttcacgaaca gttggaagtt
     1861 gatcaccact cttgatttct tggctaataa tttgcatcat gacatgttgt gctatctgcg
     1921 cataaatagg agatttttca tcaaatttcc aagacatgtg gtctcctttc tgagtaatat
     1981 agatatttgt actaattaaa tggtacagaa aaaaaagggg aatgtcaagt tttatgccat
     2041 ttttcactct ttgagaagta gacgtagatt agagagaaaa ttgaagcaag aaaacctttt
     2101 tcatagtata atagggaaca agataaccaa aggaggaact tatgtttgct caacttgata
     2161 ctaaaactgt atactcattt atggatagtt taattgactt aaatcattat tttgaacgag
     2221 caaagcaatt tggttaccac accataggaa tcatggataa ggataatctt tatggtgctt
     2281 accattttat taaaggttgt caaaaaaatg gactgcagcc agttttaggt ttggaagtag
     2341 agattctcta tcaagagcgg caggtgctcc ttaacttaat cgcccagaat acacaaggct
     2401 atcatcagct tttaaaaatt tccacggcaa aaatgtctgg caagcttcat atggattacc
     2461 tctgccaaca tttggaaggg atagcggtta ttattcctag taagggttgg agcgatacat
     2521 tagtggtccc ttttgactac tatatcggtg ttgatcagta tactgattta tctcatatgg
     2581 attctaagag gcagcttata cccctaagga cagttcgtta ttttgcgcaa gatgatatgg
     2641 aaaccctgca catgttgcat gccattcgag ataacctcag tctggcagag acccctgtgg
     2701 tagaaagtga tcaagagtta gcagattgtc aacaactaac cgccttctat caaacacact
     2761 gccctcaagc tctacagaat ttagaagact tagtgtcagg aatctattat gatttcgata
     2821 caaatttaaa attgcctcat tttaatagag ataagtctgc caagcaagaa ttgcaagact
     2881 tgactgaggc tggtttgaag gaaaaaggat tgtggaaaga gccttatcaa tcacgcttac
     2941 tacatgaatt ggtcattatt tctgacatgg gctttgatga ttattttttg attgtgtggg
     3001 atttacttcg ctttggacgc agtaaaggct attatatggg tatgggacgt ggctcggcgg
     3061 caggtagtct agtggcttat gctctgaaca ttacagggat tgatccagtt caacatgatt
     3121 tgctatttga gcgcttttta aacaaagaac gttatagcat gcctgatatt gatatcgatc
     3181 ttccagatat ttaccgttca gaatttctac ggtatgtccg aaatcgttat ggtagcgacc
     3241 attcggcgca aattgtgacc ttttcaacct ttggccctaa acaggctatt cgtgatgttt
     3301 tcaaacggtt cggggttcca gaatacgaac tgaccaatct cactaaaaaa attggtttta
     3361 aagatagctt ggctactgtc tatgaaaagt caatctcttt caggcaggtt attaatagta
     3421 gaactgaatt tcaaaaggcc tttgctattg ccaagcgtat cgaaggaaat ccaagacaaa
     3481 cgtccattca cgcagctggt attgtgatga gtgatgatac cttgaccaat catattcctc
     3541 taaaatcggg cgatgacatg atgatcaccc agtatgatgc tcatgcggtc gaagctaacg
     3601 gcctgttaaa aatggatttt ttggggttaa gaaatttgac ctttgttcaa aaaatgcaag
     3661 agaaggttgc taaagactac gggtgtcaga ttgatattgc agccattgat ttagaagacc
     3721 cgcaaacgtt ggcacttttt gctaaagggg ataccaaggg aattttccaa tttgaacaaa
     3781 atggtgctat taatctttta aaacggatta agccacaacg ttttgaagaa attgttgcca
     3841 ctaccagtct aaatagacca ggggcaagtg actataccac taatttcatt aaacgaagag
     3901 aaggacaaga aaaaattgat ttgattgatc ctgtgattgc ttccatttta gagccaactt
     3961 acggtattat gctttatcaa gaacaagtta tgcagattgc acaggtttat gctggtttta
     4021 cgttaggcaa ggccgacttg ttaaggcgtg ccatgtctaa aaaaaatcta caagaaatgc
     4081 aaaaaatgga agaagacttt attgcttctg ctaagcacct agggagagct gaagaaacag
     4141 ctagaggact ttttaaacgg atggaaaaat ttgcaggtta tggttttaac cgcagccatg
     4201 cctttgccta ttcagcttta gcttttcaat tggcttattt caaagcccat tacccggctg
     4261 ttttttacga tatcatgatg aattattcta gcagtgacta tatcacagat gctctagaat
     4321 cagattttca agtagcgcaa gttaccatta atagtattcc ttacactgat aaaattgaag
     4381 ctagcaagat ttacatgggg ctgaaaaata ttaaggggtt gccaagggat tttgcttatt
     4441 ggattatcga gcaaagacca tttaatagcg tagaggattt tctcactaga actccagaaa
     4501 aatatcaaaa aaaggttttc cttgagcctc tgataaaaat aggtctgttt gattgctttg
     4561 agcctaaccg taaaaaaatt ctggacaatt tggatggttt actggtattt gttaatgagc
     4621 ttggttctct tttttcagat tcttccttta gttgggtaga tacgaaagat tactcagcaa
     4681 ctgaaaaata ttctttggaa caggagatcg ttggggttgg catgagcaag catcctttaa
     4741 ttgatattgc tgagaaaagt acccaaactt ttactcccat ttcacagtta gtcaaagaaa
     4801 gcgaagcagt cgtactgatt caaatagata gcattaggat cattagaacc aaaacaagtg
     4861 ggcagcaaat ggctttttta agtgtgaatg acactaagaa aaagctcgat gtcacacttt
     4921 ttccacaaga gtatgccatt tataaagacc aattaaaaga aggagaattc tattacttaa
     4981 aaggtagaat aaaagaaaga gaccatcgac tgcagatggt gtgtcagcaa gtgcaaatgg
     5041 ctattagtca aaaatattgg ttattagttg aaaaccatca gtttgattcc caaatttctg
     5101 agattttagg tgcctttcca ggaacgactc cagttgttat tcactatcaa aaaaataagg
     5161 aaacaattgc attaactaag attcaggttc atgtaacaga gaatttaaag gaaaaacttc
     5221 gtccttttgt tctgaaaacg gtttttcgat aaaaatggac aattagtgaa gtattttgca
     5281 aatgaatgtg ctataataag accgttaaat taattaaagg agtaccagaa aatgaaacgt
     5341 attgctgttt taaccagtgg cggcgacgct cctggtatga acgctgctat tcgtgcagtc
     5401 gttcgtaaag caatttcaga aggaatggaa gtttatggta tcaaccgtgg ctatgcaggt
     5461 atggttgatg gcgacatttt cccactgggt tcaaaagaag ttggtgataa aatctcacgt
     5521 ggtggaactt tcttatactc agctcgttat ccagagtttg ctcaacttga aggtcaattg
     5581 gctggtattg agcaacttaa aaaacatggt attgaaggtg ttgttgttat tggtggggat
     5641 ggttcttatc atggcgctat gcgcttgaca gagcacggct tcccagcggt aggtatccca
     5701 ggaacaatcg ataacgatat tgcgggaact gactacacta tcggatttga tacagcagtt
     5761 aacacagcag ttgaagctat tgataaactt cgtgacacct catcaagtca cggacgtact
     5821 tttgtggttg aagtgatggg tcgcaatgcg ggtgatattg ctctttgggc aggtattgct
     5881 agtggtgctg atcaaatcat tgttccagaa gaagagtttg atattgaaaa agtggcatca
     5941 acaatccaat atgattttga acacaaaggt aaaaatcacc acattatcgt cttagctgaa
     6001 ggtgttatga gcggtgaagc ttttgctcaa aaactgaaag aagctggcga taagagtgac
     6061 cttcgtgtga caaatcttgg ccacattctt cgtgggggtt caccaactgc tcgtgaccgt
     6121 gtcattgctt cttggatggg ttcacatgct gttgagctac ttaaagaagg caaaggtggt
     6181 ttggctgttg gtattcacaa tgaagaactt gttgaaagcc caatccttgg tactgcagaa
     6241 gaaggtgctt tgttcagctt gactgaagaa ggcaagatta ttgttaataa tccacacaaa
     6301 gctcgtttag actttgcagc tttgaaccgt tcattgtcac aataagttta gttaaaattg
     6361 ttaaatcgtc aattattgac aaaaaaataa gggagtttca gagtaaaatg aataaacgcg
     6421 taaaaatcgt tgcaacactt ggtcctgcgg ttgaaatccg tggtggtaaa aaatacggag
     6481 aagatggcta ctgggctggt caacttgatg ttgaagaatc tgcaaaaaaa atcgctgaat
     6541 taattgaagc tggtgcgaat gttttccgtt tcaatttctc acatggtgac cacaaagaac
     6601 aaggtgaccg tatggcaact gttcgccttg cagaagaaat tgctcgtcaa aaagttggtt
     6661 tccttttgga tactaaaggt cctgaaatgc gtacggaatt gtttgcagat gatgctaaag
     6721 agtttagcta tgttactgga gaaaaaatcc gtgtagcgac tacacaaggt attcaatcaa
     6781 ctcgcgatgt tattgctttg aacgttgctg gtagccttga catctacgat gaagtagaag
     6841 taggtcatac tattcttatc gatgatggta aacttggttt gaaagtgatc gacaaagata
     6901 tcgcaacacg tcaatttatc gttgaagtag aaaacgacgg tattattgct aaacaaaaag
     6961 gtgttaatat ccctaacact aaaattcctt tcccagcact tgcggaacgc gacaatgctg
     7021 atatccgttt tggtcttgaa caaggactta actttattgc aatctcattt gttcgtacag
     7081 caaaagacgt tgaggaagtt cgtgaaatct gtcgcgaaac tggtaacgac catgtgcaat
     7141 tatttgctaa gattgaaaac caacaaggta tcgataatct tgatgaaatc atcgaagctg
     7201 ctgatggtat catgattgca cgtggcgaca tgggtatcga agtaccattt gaaatggttc
     7261 cagttttcca aaaaatgatt atcactaaag tgaatgcagc tggtaaagca gttatcacag
     7321 caacaaacat gcttgaaaca atgactgaaa aaccacgtgc gacacgttct gaagtatctg
     7381 acgtcttcaa tgctgttatc gatggtactg atgcaacaat gctttcagga gagtccgcta
     7441 acggtaaata cccggttgaa tctgttcgta caatggcgac tattgatcgt aatgcacaaa
     7501 ctcttcttaa cgaatatggt cgtttagatt catctgcctt tccacgtacc aataaaacag
     7561 atgttattgc ttcagctgtt aaagatgcca ctcattcaat ggacatcaaa cttgttgtga
     7621 ctattactga gacaggtaat acagctcgtg cgatttctaa attccgtcca gatgcggaca
     7681 tcttagctgt aacatttgat gaaaaagtac aacgtgcttt gatgattaac tggggtgtta
     7741 ttcctgttct tgctgaaaaa cctgcatcta ctgatgacat gtttgaagta gcagagcgtg
     7801 ttgctgtgga ggcaggctta gttcaatctg gggataatat tgttattgtt gctggtgttc
     7861 cagttggtac tggtggaacg aatactatgc gtgttcgtac agtaaaataa atgtgttata
     7921 actatttacc taaaggttag aaggcaagct tctaaccttt tttgatatca aaaatatcat
     7981 gttaattcac tagtgttaat ttactttaat gagtctaagt ttgtatttta tacagaatga
     8041 gaaacgttta ttggtattga tcaaaaattg tttacttttt ttctagctta gaacatggta
     8101 taataagaca atagactagg agttaatatg gtaaagcgag attttataag aaatatatta
     8161 ttgttattaa ttgtgattat tggggctatt ttgttgagaa tctttgtttt ttcaactttt
     8221 aaagtttctc cagaaacagc taatacttat ttaaagagtg gtgatttagt cacaatcaaa
     8281 aaaaatattc agcccaaata taaagatttt gtggtttata gagttggaaa aaaagattat
     8341 gtcagtcgag tcattgctgt tgaaggcgat agcgtgactt atatggacga tattttttac
     8401 ctcaataata tggtagagtc acaggcttac cttgaaaaga tgaaagcaca ttacttgaat
     8461 catgcaccgt ttggcacatt gtatacagat gattttacag ttgctaccat cacagctgat
     8521 aagtatcaaa aagttcctaa ggggaagtat cttcttttga atgataaccg gaaaaatacg
     8581 aatgacagtc gtcgatttgg gttaataaat gcctcgcaga ttaaaggttt agtgaccttt
     8641 agagttttgc ctctcagcga ttttggattt gtagaagtag agtagttgtc aggctactct
     8701 acttttttta taattagact ataccaattt tatgtttgac aagacattgt ggatattata
     8761 tactgtaaac ataatgtttt tatcggtata attagactat accaattatt gaaattatga
     8821 gagaaagtag caagttaacg aacttgttaa ggtaattaag atgtgtggaa ttgttggagt
     8881 tgttggaaat cgcaatgcaa cggatatttt aatgcaaggc cttgaaaagc ttgaataccg
     8941 gggttatgat tcagcaggaa tttttgtggc taatgcccat caaacaaact tgattaaatc
     9001 agtggggcgg attgctgatt tgcgtgccaa gattggcatt gatgttgctg gttcaacagg
     9061 gattggtcac acccgttggg caacgcatgg ccaatcaaca gaggataatg cccatcctca
     9121 cacgtcacaa actggacgtt ttgtacttgt tcataatggt gtgattgaaa attaccttca
     9181 cattaaaaca gagttcctag ctggacatga ttttaagggg cagacagata ctgagattgc
     9241 agtacacttg attggaaaat ttgtggaaga agacaagttg tcagtactgg aagcttttaa
     9301 aaaagcttta agcattattg aaggttccta cgcctttgcg ttaatggata gccaagcaac
     9361 tgatactatt tatgtggcta aaaacaagtc tccattgttg attggacttg gtgaaggtta
     9421 caacatggtt tgttcagatg ccatggccat gattcgtgaa accagtgaat ttatggaaat
     9481 tcatgataag gagctagtta ttttaaccaa agataaggta attgttacag actacgatgg
     9541 taaagagctg atacgagatt cctacactgc tgaattagac ttatctgata ttggcaaagg
     9601 gacttatcct ttctatatgc tgaaagaaat tgatgagcaa ccaaccgtaa tgcgtcaatt
     9661 aatttcaact tatgcagatg aaactggtaa cgtacaggtt gatccagcta tcattacctc
     9721 tatccaagag gctgaccgtc tttatatttt agcggcaggg acttcctacc atgctggttt
     9781 tgcaacaaaa aatatgcttg agcaattgac agatacacca gttgagttgg gcgtggcttc
     9841 tgagtggggt taccacatgc ctctgcttag caagaaacca atgtttattc tactaagcca
     9901 atcaggagaa accgcagata gtcgtcaagt tttagtaaag gcaaatgcta tgggcattcc
     9961 gagtttgaca gtaactaacg ttccaggatc aaccttatca cgtgaagcaa catacaccat
    10021 gttgattcat gctggacctg aaattgctgt tgcgtctaca aaagcttaca ctgcacaaat
    10081 tgctgccctt gcctttttgg ctaaggcagt tggtgaggca aatggtaagc aagaagctct
    10141 tgactttaac ttggtacatg agttgtcatt ggttgcccaa tctattgagg cgactttgtc
    10201 tgaaaaagat ctcgtggcag aaaaggttca agctttgcta gctactactc gtaatgcttt
    10261 ttacatcggg cgtggcaatg attattacgt tgcgatggaa gctgctttga aattaaaaga
    10321 gatttcttat attcaatgcg aaggctttgc ggctggtgaa ttgaaacatg gcaccatttc
    10381 attgattgag gaggacacgc cagtaatcgc tttaatatcg tctagtcagt tggtttcctc
    10441 tcatacgcgt ggtaatattc aagaagttgc tgcccgtggg gctcatgttt taacagttgt
    10501 ggaagaaggg cttgaccgtg agggagatga cattattgtc aataaggttc attctttcct
    10561 agccccgatt gctatggtca ttccaactca actgattgct tactacgctt cattacaacg
    10621 tggacttgat gttgataagc cacgtaattt ggctaaagct gtaacagtag aataaatgat
    10681 tataatggat aaggcaacca tctgttaggt ggttgctttt tgtttttagg agaatagcag
    10741 agcttagaaa atggccttga gaagaatagt catcttctga tgagaacgta ttcatcttgt
    10801 caaatcattg attctaaagt aaaatggtaa cattaagaaa tgtttaggag tgtaagatgt
    10861 cattaccaaa ttgtttgcaa tgccagtctg aatatgttta cgaagatggt cttttattaa
    10921 tctgtccaat gtgtgctttt gaatggacac caggcgaaga agcgactgaa gaagaaggac
    10981 ttgttgtttt ggatagcaat ggtgtccgac tgtctgatgg tgataccatt actgtggtta
    11041 aagatttgaa agtaaaaggc gctccaaaag acctgaaaca aggaactcga gttaaaaata
    11101 ttcgcctggt ggaaggtgat cataacattg attgtaagat tgatgggttt ggcgcgatga
    11161 aattgaaatc agaatttgtc aagaaaatct aataataata cgcaaccagc tgatctggtt
    11221 gtatttttat aaaaaaatct ctccccaaat acgttcaaat ttggtataat agtaaaatat
    11281 ttagttttag gaggcaacat gacctatatt cagcaagttt tacccagctt attagatggt
    11341 gccttggtga ccttacaagt attctttatt gttatcattc tttctatacc cttagggact
    11401 attttagctt tcttgatgaa gattcccttt aaaccgctac agtggttttt gaccctatac
    11461 gtgtggatga tgcgagggac accattacta cttcaattga tttttttcta ttatgttttg
    11521 ccaagtgtgg ggattagttt tgatcgaatg ccagctgcta ttttggcgtt tactttgaat
    11581 tatgctgcct actttgctga aatttttaga ggtgggattg aggctattcc aaaaggtcaa
    11641 tatgaagcag ctaaagtatt aaagttaaaa cctcttcaaa ccattcgtta tattattttg
    11701 cctcaagtgt ttaaaattgt gttaccaagt gttttcaatg aagtcattaa tttggtcaaa
    11761 gattcttctc ttgtctatgt actcggtgta ggagatcttt tattagcaag taagacggca
    11821 gccaataggg atgcaacctt agcccctatg tttatcgctg gtcttatcta tttgctttta
    11881 attggactgg tcacgattat ttcaaaacaa gttgaaaaac ggtttaatta ttatcagtaa
    11941 ggaggcttca tgttagaact caaaaatatt tccaaacagt ttggtcaaaa aaccattttt
    12001 gatggcttta atctaaccgt tcaagacgga gaagtgctct ctttggtagg cccatcaggt
    12061 ggcggtaaga caacactctt acggatgttg gctggtcttg aatctattga ttcaggtcaa
    12121 gtcttttaca atggcgaaga tgttggtatt gatcatttgg aaaatcgtaa cttgcttgga
    12181 tttgttttcc aagattttca attgtttcct catcttaccg ttttagacaa cctaacgctg
    12241 tctccaacaa ttacaatggg caagcaaaag gctgacgcta aagaaaaggc tttggattta
    12301 ctggcacgtt taggattaaa agaacatgcc caagtttatc cctattcgtt atctggaggt
    12361 caaaaacaac gggttgcttt ggcaagagcc atgatgattg cccctcaaat tatcggttac
    12421 gatgaaccga ccagtgctct agatcctgaa ttacgtcaga cggtagaagc cttgattgtt
    12481 caaaaccgtg aaatgggaat aactcaaatt gtagtcactc acgatcttgt ttttgccgaa
    12541 gccatctcag atcgtattat tagggttaat cctaaataga agaggaccca aaagatgatt
    12601 ataaaaaaaa gaaccgtagc aattttagcc atagctagta gctttttctt ggtagcttgt
    12661 caagctacta aaagtcttaa atcaggagat gcttggggag tttaccaaaa gcaaaaaagt
    12721 attacagttg gttttgacaa tacgtttgtt cctatgggct ataaggatga aagcggcaaa
    12781 tgcaaaggtt ttgatattga tttggctaaa gaagtttttc accaatatgg actcaaggtt
    12841 aactttcaag ctattaattg ggacatgaaa gaagcagaac taaacaatgg taaaattgat
    12901 gtaatctgga atggttattc aataactaag gagcgtcagg ataaggttgc ctttactgat
    12961 tcttacatga gaaatgaaca aattattgtt gtcaaaaaaa gatctgatat taaaacaata
    13021 tcagatatga aacataaagt gttaggagca caatcagctt catcaggtta tgactccttg
    13081 ttaagaactc ctaaactgct gaaagatttt attaaaaata aagacgctaa tcaatatgaa
    13141 acctttacac aagcttttat tgatttaaaa tcagatcgta tcgatggaat attgattgac
    13201 aaagtatatg ccaattacta tttagcaaaa gaagggcaat tggagaatta tcggatgatc
    13261 ccaacgacct ttgaaaatga agcattttcg gttggactta gaaaagaaga caaaacgttg
    13321 caagcaaaaa ttaatcgtgc tttcagggtg ctttatcaaa atggcaaatt tcaagctatt
    13381 tctgagaaat ggtttggaga tgatgttgcc actgccaata ttaaatctta aaaaggacac
    13441 ttgtcctttt tttgtttaac aggtgagatc tagcagacaa agtcagctag atgatttaat
    13501 aaaaatctta gtttaaggtt ttttt
//
LOCUS       DAUGUF010000042         9056 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUGUF010000042 DAUGUF010000000
VERSION     DAUGUF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9056
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.042"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(151..306)
                     /locus_tag="VIB71_001509"
     CDS             complement(151..306)
                     /locus_tag="VIB71_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEQ8823236.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(809..2215)
                     /gene="lacG"
                     /locus_tag="VIB71_001510"
     CDS             complement(809..2215)
                     /gene="lacG"
                     /locus_tag="VIB71_001510"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEQ8823237.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVNYAELCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(2288..3985)
                     /locus_tag="VIB71_001511"
     CDS             complement(2288..3985)
                     /locus_tag="VIB71_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8823238.1"
                     /translation="MNGLIAQIEKGKPFFEKMSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIESLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFMSTMLAAIVGFLLMAANPAKEGGFLTGFMGTKGLLTAFIAAFITVNVYKTCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHSTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKIYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKEQMEK"
     gene            complement(3985..4302)
                     /locus_tag="VIB71_001512"
     CDS             complement(3985..4302)
                     /locus_tag="VIB71_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ8823239.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(4326..5309)
                     /gene="lacD"
                     /locus_tag="VIB71_001513"
     CDS             complement(4326..5309)
                     /gene="lacD"
                     /locus_tag="VIB71_001513"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ8823240.1"
                     /translation="MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEVGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDINEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKISDNASPEFAKVKAHKVNEAMKVFSEERFGVDVLKVEVPVNMKFVES
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(5313..6242)
                     /locus_tag="VIB71_001514"
     CDS             complement(5313..6242)
                     /locus_tag="VIB71_001514"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEQ8823241.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNDFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPLLSVDEIDGFTHQFKYLLNDVDVVTMSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            complement(6288..6803)
                     /gene="lacB"
                     /locus_tag="VIB71_001515"
     CDS             complement(6288..6803)
                     /gene="lacB"
                     /locus_tag="VIB71_001515"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ8823242.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(6838..7266)
                     /gene="lacA"
                     /locus_tag="VIB71_001516"
     CDS             complement(6838..7266)
                     /gene="lacA"
                     /locus_tag="VIB71_001516"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ8823243.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            7712..8485
                     /locus_tag="VIB71_001517"
     CDS             7712..8485
                     /locus_tag="VIB71_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ8823244.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLETLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
BASE COUNT         2839 a         1763 c         1454 g         3000 t
ORIGIN      
        1 aattgagtta aagtattcgt aaaactgatg ttgctgatac tctaacttta attcatttct
       61 ttttatcatt ttttcctacc actacttaaa aatcctgcct agactaagtc taaacaggaa
      121 attttagtct gcttatccag attgttttaa ttaacaacaa acaaatactg agttcggaca
      181 gtcatcagta atagttgcaa accaacctga acctttttta ccaccagcta cttccataag
      241 ttctttttca gaaacttctt cgatagcatt agtcaaaata tcctttgaat ttttcataaa
      301 actcattctc cttcctatca gtatgtagtg actattttct acacttttat tgtaaataat
      361 acgtcttcat tttcaatgag taaaaagtgc aaaaatgact tttttcatat tttttagtaa
      421 gatttttgag atgtcacata agaggtcact ttataacaaa tagccctctg atataaaaaa
      481 caaaactcgt tctttacagc tattttacaa tctaatcgct tctcgttata acatcaatct
      541 ctaatcagaa aatggttact ttacttattt aatcaggtca ggagtttgaa tgacagaagt
      601 caaatatctg aaaaaggatg ttaaataaaa ctttcaaaac ccattttcat caactaaaaa
      661 cacttataac ccgatcttac aactaatgga ttaccatcaa cagcaaataa tactatgctt
      721 gaaaaatgtc aacatcatct actttttgtg actataattc agtaaacgaa catgaagtgt
      781 aaaaatgtat taaaaaagta tctcaaaatc attcaatcac ttgagtttct gctacttttt
      841 tataccagta ggcactcttc ttaggataac gttcttgagt ttcaaaatcg acatagaaga
      901 gaccgtaacg tttttcatag ccatttgacc atgaaaagac atccatcagt gaccacataa
      961 agtatccttt aacatttgca ccatcagaaa tagcatcaga aataacttct aagtgttttt
     1021 tcacataatc gatacgtcca tcatcataga cagtattatc tacaaactca tctttgtagc
     1081 caagaccatt ctctgtaatg taaattttct tgtagttagg ataatcggct ttgacacgca
     1141 tgatttgatc atataagcct tgtgggaaga taatccagtc ccagtccgtt tttggaacat
     1201 caacgggtgc ttttcttcga ccaacaccct tgatttggta tttagagctg cctttttcac
     1261 ccttaccatt gtgaatgatt tcagtctcac catcaaaagc ttgcatccaa tcactcatat
     1321 agtagttaat accaaggaag tcattcaaat cttttgcagc gtctagtgca gcaaaatctt
     1381 cttcacgaag atcaagttca ccaccattca cctcaaggat atggttaaca ccttccattg
     1441 ttttatctga atacttacct agataagttg catcaagaat aaatttatta tggatgatat
     1501 cttccagttc agctgctcta acatcatcag gattgttagc gtcaaatgga tacttagttg
     1561 gaagagcatg gacaacacca atttcacctg aataaccact atctttaaag agtttgactg
     1621 cacgagcatg agagaccatc atgttatgat gtgattggaa aactttagca agatcatatt
     1681 ggatacctgg agggaattta ccaaccaagt attgaccatc gccaattggt ccaatttcgt
     1741 tgaaggttgt ccaatagtta acttctgaga attctttaaa acagagttct gcataattta
     1801 caaaatgttc aatgttctca cgattgagga aatcaccatt tgaatgaagt gcttctggtg
     1861 tatcaaaatg gtgaagtgta acaaaaggct caacatgacg cttatgacac tctgcaaaaa
     1921 gattgtggta gtattctact cctttagggt taacttctcc ttttcctgtt ggaaaaatac
     1981 gagaccaggc aatagagata cggatcccat taacaccaaa ttcttcacta agtttcaaat
     2041 cgacagggta acgattataa aaatcacttg ctggctcagc tgtgtaccaa tagttgtctt
     2101 ctaagtattt atcccaagct actggtcctt taccatctgt gtgggtagcg ccttcagcct
     2161 ggtaagcagc tgtagcacca ccaaaaataa aatctttagg taatgtttta gtcatgatat
     2221 acctcttcta aattttcatt tcactataaa ggaagattga gtacccccaa ccttccctag
     2281 cgacatatta tttttccatt tgttctttaa cgaagtctaa tgcgccttga ccatcgcgag
     2341 tcaatttgat gtattgagcc ccttctgttt tagctaattt aatatcaagt ttatcagttt
     2401 ccactttcat atcttcatag ttagaagcta cttgaggtgc aaggataaca agttgatatt
     2461 gtggtaaaat ctcacggtga gcaccataac ttcctgctgc tgcagtgaca ggtgcaccat
     2521 attctttagc tgctttattc aaagcgtttg caagcaaacc acttgtacca ccaccggcac
     2581 aaagaacgag aacattagtt tgatcagtga tttctttggt ttctttagct gctgattttt
     2641 caagaatagc atcagctttt ttagtatcaa agtttgctgc tactttttct ttgagggcat
     2701 ctgatgaatt cgtacctgct gcttcttcag caagaatttg ctcatcataa attttcaaga
     2761 atgggtagta gatgatgaca tcaactacga ttaacaaagc tgccaaaatg aatgctagca
     2821 cttggaagtt tgtaccaagg ataagaccca atggagctgg tgttgtccaa ggtaagtttg
     2881 cagtgaaact gttcattcca agtgtgtcaa tgaagaattt gaaaatccat acattgacaa
     2941 ttggtgccaa gataaatgga ataaagaaga ttgggttcaa aacaagtgga gcaccaaaca
     3001 aaatgggttc gttaacacca aagaatgttg gaacaactga tgcacgtcca atggctttgt
     3061 tacgttttga ttttgttaac cacatgaaca tgaatggaac gacgagagtt gcaccagtac
     3121 cacccatggt aacgatgaac atttgagtcc ctgaagtcaa aatcttgtca gcatgttcac
     3181 cagcttgaag taattgaagg ttggtttcag catttgcgta agtaatcgct gcaatggctg
     3241 gttcaacaat agatggtcca tgaataccaa caaaccagaa gaaagcaaat gcaccgaaga
     3301 taatagtgat tccaacatag ccatctgctg cttggaacaa tggtgcaaga agtttaccaa
     3361 ttgactcggc aacgttaacg cctaaagtac tatgaacaat caattcaatc acataaagca
     3421 gtacaactga taacgtaaat ggaatcaaat ctttaaaaac ttgagagatg tttggtggca
     3481 cctcttctgg catgcgaata gtgacattgt ttttcacaca ggttttatag acatttacgg
     3541 taataaaagc tgcgatgaag gctgtcaaca aaccttttgt tcccataaat ccagttaaga
     3601 aaccaccttc ttttgctgga ttggctgcca taagtaaaaa acctacaata gcagcgagca
     3661 tggtagacat gaagttgatt tggtttgtgc ttggtaatga tcgattcatt gagtcagtta
     3721 aagctttggc tgtcgtacca gccacaaaca aacctaaaat acccattgag tagttgtatg
     3781 gcgtcatcaa gagactctca atatccttac tccaatggaa gccccatgca tttggaacat
     3841 aggcaatcaa gataaagata cttgaaaaca agataactgg cataccagcg ataaaaccat
     3901 cacgaatagc gcgaagatag atatttcgag acattttctc gaagaaaggt ttccctttct
     3961 caatctgagc aattaatcca ttcattattt tgctcctctc ttataaagtt caatcatgtg
     4021 tttcattaaa tcttgtaata aaatggtcgt cattaaatga tcttgaccgt gcattaaagt
     4081 gacactataa gctaagtcat ctccagctgc ttctttttgt agtagacttg tctgagcatt
     4141 gtgagcatca ttcaagcagt cactacctgc agcgattaat tcttctgctt tagcataatc
     4201 tccttcttgc gctgctttaa gcgcttccaa aaattttgaa cgggcatcac cagcataggc
     4261 tacgatttca aaacctaaaa gagtagtttc ttctctattc attgtagttt cctccgaaaa
     4321 taatgttaca ttttttcagt ccaaggactt gcagttttat ctagcacttt gtttaattcg
     4381 tcaatatttt tgaaaccttc tgtacgcaac cattcacgag ctgcttgtgg tccttcttcg
     4441 atatagactt ttacagatcc tgcccaggta gcacgtccac ataagacacc gttgaattta
     4501 gcacctgatt ctgctgcaaa caccaaagta tcttggaaca atttggcaga aacacctgca
     4561 ctcaagtaaa tatatggtaa atcagtagaa gcttcttgat cacggaaagc ttgagctgct
     4621 tcttcttttg taaagagaac ctcaccatct gcaaagcttt ctacaaattt catatttact
     4681 ggaacttcga ctttcaagac gtcaacacca aagcgttctt ctgagaagac tttcattgct
     4741 tcattaactt tatgagcttt aacttttgca aactcagggc tagcattgtc agagattttc
     4801 tcatcataag ttagaatttc taagtagaat ggaatatctt ctgcacggca ttcagaacca
     4861 atacgttcaa tgtaagcttt tttctgctcg ttgatatctt gatctccatc aatatcatag
     4921 taaagaagga atttaactgc ttctgctcca gcttctttaa tacgttttgc agaccaaaca
     4981 tctaagcaat caggtaagcg actagttgtt gttgcatcgt atcctgtttt ctcatatgcc
     5041 aacaacaagc ctacttcttc tgaacgaaca cgacttgctg gcaagccata ttcaggatca
     5101 agtaaaattg atgatgcaaa tggtgttagt tcttcagaaa ctaaactttt aagctcttca
     5161 atttgttcta ctgttggctc ttttgtttga tgttgagcca tcatacgttt gagagctcca
     5221 cgttggtcaa aagctaaagc agaaataaca ccatctatac ttagtttttc catgctttta
     5281 cgtttgtttt cagttaaagt aattgtcatt ttttatacct ctttgacttt aatagattga
     5341 tataacttat cgtaatttgc catgttaaca tgcccagttg ttttttcttg cgcatttaac
     5401 atccctaaga catttgcttt tgttaataaa gctcgatcat cttcatcatt cgctaaacct
     5461 gaagcaatac ctgccactgt agaatcccct gaacctacag cgcttacaat tttgatttta
     5521 ggaatgtcaa cgttataaaa tgtatccttg tgctttgcaa atacaccatc agcaccaaga
     5581 gaaacgatta tccattcaat tccttcaaat agttcatctt gtaagacttc ttttaaggct
     5641 tcaaaatctt ttgtcatttc tttacctaaa agttgagaaa gttcttcaag attaggcttg
     5701 ataactgttg gtttactatc acctttcaat actgcttcta gagcatttcc agaacaatcc
     5761 agaaccgttt tcttaccatt aagattggca atcttgatta acttctgata gtaatcatct
     5821 ggcataccag caggcaaact gcctgacatt gtcactacgt caacatcatt cagtaaatac
     5881 ttaaattgat gagtaaatcc atcaatttca tctacactta acagcggtcc tttttctaaa
     5941 atctccgttt gattaccttc gtgtaaaatg gctatacaag ttctagtatc acctgaaatt
     6001 ttatagaagc gacttaaaat cgaatcagga agatgattaa tgataaaatc accgctttct
     6061 ccacctacac aacctgtagc tttgactgtc tcaccaaagt catttagaac tcgggaaaca
     6121 ttcaagcctt taccaccggg tgtctttgta acgtctacaa ctcgattgac agtatcgcat
     6181 tttagctcat ccaaagggta ggagacgtca atagctggat ttaaagtaac tgttaaaatc
     6241 acaatagctc ctttttctat atatccttat cataattctt tcaaatatta gtcgtgatat
     6301 tcaccacggt cccatttttc tagaaattca tcaaagaagt gtgggttgtt ttgatcttgg
     6361 ctagcatgtt gcaagctatc cattttttca atccattttt tattttcttc agttggtttg
     6421 tattccgcgg ctaagaaagc atcgataata tcattcatca ataaaccacc gatgattttt
     6481 ccaccaaaac caataacgtt tgcgtttagc tcttcttttg agtagatagc agatgtcata
     6541 tctctaacga gtgctgaacg aattccagga actttgttta cggcatttgt aataccaaca
     6601 ccagtaccac agataacaac acctagttct gcttcaccac ttgctactgc ttcaccaact
     6661 tttttaccaa aaattggata gtgtgtgcga acattatcat acgtaccaca atcaataact
     6721 ttatgacctt gtgattttag gtaatccaca acagcgattt tttcataagt aacaatatgg
     6781 tcacaaccta cagcaatttt catttttgtt ctccttgttt taacctattt caatcaatta
     6841 gcacatttta ttaagcatgt cgacacgaac ttgatgacgt ccaccatcat atttaccttc
     6901 gacaaagcct ttgataatgt tctttgcaat tcctggagca ctaatttcag aaccaagcgt
     6961 gatgattcga gcattgttgt gtcctcttgt catgtatgct gagcgctcat ctgatacttc
     7021 agctgccacc attcctttga ttttagtagc taccatgaaa gaaccaacac catatgcatc
     7081 aatgacaata cctaagttat cttcggaggc attaacttct tttgcaacgg ctaaagttgt
     7141 atctacaaag tcacgtactt cgttttcact aacatcaacg acttcgtatt taccttcttt
     7201 aaggtaatct ttgataactt ctttaagttc ttgacctgct ttgtcagcac cgataataat
     7261 tgccatttta tttctcctat gatttagaat aagtaaatgt ggaaaaccta cgtagatagt
     7321 taattaacga tttgcaacat cttttgaaat aacgctttca ttatttctat gacctaatca
     7381 tacacccacc aaacataaaa gtcaacattt ttttgtttat ttttataaaa aataaacaaa
     7441 atatgtttat ttttttcatt tttacgttat tatcctaata tttcttgtgt ttctttttca
     7501 tttcataaat ccctttgaca gccactcgta acctatcata tattacgaga cccttatctc
     7561 tatttattgt aaacgtttta tttaaaacgt tttctatttt gttaattttt gttttttcca
     7621 atatttatgt ttgttttgtt tgattttttt attgatatta tgttatgata cctttaatag
     7681 ttatacccta agacactgat aggagataag aatgaaaaag aaagagcgtc atgaaaaaat
     7741 tctcgatatc ttaaaagttg acggttttat aaaagtaaaa gatattatcg atgaaatgaa
     7801 catctcagat atgaccgcta gacgagatct cgatacattg gcagataaag gattacttat
     7861 caggacccat ggtggtgctc aatatttgga ttattcttca gcaaaggacg aaggtcacga
     7921 gaaaacacac actgaaaaga aggtcttaca gactaccgaa aaaaaacaaa ttgcacaaag
     7981 agctaaaaac attattaaag atggcgaaac tgtctttata ggtccaggga caacattaga
     8041 gcatctagct gtcgaattaa aaaatagaaa tatcagggtc attacaaata gccttcctgt
     8101 ttttttaatt ttgcacccga gcactactat tgatttgatt ttaattggtg gtgaatgtcg
     8161 tgaaattact ggagcttttg ttggtgctat tgccattaat aacctagaaa cattgacatt
     8221 ttcaaaagct tttgtcagcg caaatgcagt ttacaataat tctattgcga cgtacagtga
     8281 tctcgaagga gaagttcaaa gggttgcatt gaataatgct gttgagaaaa tccttctagt
     8341 tgatagtacc aagtttgaaa gttatgactt ctataatttc taccaactag atcaagtgga
     8401 cttaattgtg actgataaaa atgtgacaac tgatatcata gaaaagtaca agaaattctc
     8461 aaaaatcata atcgctgaca agtaaaagac ctactcatat taaaaagcac ttcagggttt
     8521 agatatatcc cctgtcaagt aaacagggag catatctgaa agtagtgttt gtgttataaa
     8581 gaagtttctt gttaacttat tttctggttt ttttcagact tatcagtctt gtactgttcc
     8641 tttttctgat gaataacgtg gaaataggca gacagctata tatttcacct ctagaatggt
     8701 tgccattact gtcatcaaga catgcttgtt ctttatcgta tggagtgaag ctttctttta
     8761 gacatcaaaa tacctcttaa gtagattttg gttcgttacc atgtctactt aagaggtgtc
     8821 ttcaaagcgc tttaaaacgt tgatataaca gtatattaac gttttgagaa ttgtgaagct
     8881 ttacgagctt ttttaagacc tggtttttgg ttcactccat tatttaaagt caaatccctt
     8941 taaaatcaat gtttctaaaa tgaaaaatca ctaaaaatct tatttataga caaatactta
     9001 aacctaaacg gtatcaaaaa taagtttcgg agcttatcaa ataatgaaaa tctgtc
//
LOCUS       DAUGUF010000043         8959 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUGUF010000043 DAUGUF010000000
VERSION     DAUGUF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8959
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.043"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            316..633
                     /locus_tag="VIB71_001518"
     CDS             316..633
                     /locus_tag="VIB71_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ8823245.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRAKVNQLAFMVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFMNGFQSIN
                     WIK"
     gene            757..2655
                     /gene="mnmG"
                     /locus_tag="VIB71_001519"
     CDS             757..2655
                     /gene="mnmG"
                     /locus_tag="VIB71_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEQ8823246.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            2745..4721
                     /locus_tag="VIB71_001520"
     CDS             2745..4721
                     /locus_tag="VIB71_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEQ8823247.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            4718..5170
                     /gene="rplI"
                     /locus_tag="VIB71_001521"
     CDS             4718..5170
                     /gene="rplI"
                     /locus_tag="VIB71_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEQ8823248.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            5200..6567
                     /gene="dnaB"
                     /locus_tag="VIB71_001522"
     CDS             5200..6567
                     /gene="dnaB"
                     /locus_tag="VIB71_001522"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEQ8823249.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            6584..6856
                     /locus_tag="VIB71_001523"
     CDS             6584..6856
                     /locus_tag="VIB71_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEQ8823250.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            7586..8197
                     /gene="rpsD"
                     /locus_tag="VIB71_001524"
     CDS             7586..8197
                     /gene="rpsD"
                     /locus_tag="VIB71_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEQ8823251.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(8351..8884)
                     /locus_tag="VIB71_001525"
     CDS             complement(8351..8884)
                     /locus_tag="VIB71_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ8823252.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFRTEELSQTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
BASE COUNT         2935 a         1426 c         1813 g         2785 t
ORIGIN      
        1 ctcgctagat tagacatagt gatacttttg taatcatttt aaaaacatta caatagattg
       61 acagagctgt aaaaacattg acattactgt aaaggtctgt gatgaaatca atattgacaa
      121 tcactaatca tttttttaaa atagatagta acaatcggaa tgatggtcaa agctcatgaa
      181 agttgtaggt ttttttgtcc tgcaatcttc tagggttttg gcccttttat ggtttagctc
      241 tagaaatgag atggctaata ggactggaat ttaaaatcac tagaggtcag ataactttag
      301 tttacgagct agcgcttgat tgttagaaat ggtaagaatt ttttaactag agatgcagct
      361 gaccaatatt acaccattgg tggtacaagt ttggtaggtg aaaaaacgca tgaaactgtt
      421 ttacgtgaaa ccttagagga agttggtatt cgagctaagg ttaatcaact ggcttttatg
      481 gttgagaatc attttgatat cgatgatgtt ttctggcata atattgaatt tcattatttg
      541 gtaagcccct tagaagaccc taaactagaa atgatagaga atgcaagcga cagatttatg
      601 aatggattcc aatcaatcaa ctggatcaaa tgaatcttgt tcctgagttt ttacaaaccg
      661 agttggctaa atggccagga catattgtcc gcattgaagg ctaaactaaa gcgtatgatt
      721 ttaaatgaat agactgaaat aaaggatttt aaaaaaatga cacatgaatt tacagaaagc
      781 tatgacgtca ttgtcatagg tgcaggtcat gctggtgttg aagccagttt ggccactagt
      841 cgtatgggtt gtaaaacttt attggcaaca atcaaccttg atatgttggc ttttatgccg
      901 tgtaatcctt ctattggagg atctgccaaa gggatagtag tacgagaaat cgatgctctt
      961 ggcggcgaaa tgggtaaaaa tattgataaa acctatatcc agatgaaaat gcttaataca
     1021 ggtaagggac cagctgtacg cgctctccga gctcaagcag ataaatccct gtatgcgcgt
     1081 gagatgaaac atacggttga aaaacaggct aatttgactc ttcgccaaac gatgattgat
     1141 gatattctag ttgaagatgg acgagttgta ggtgttttaa cagccacagg acaaaagttt
     1201 gcagctaagg cagttgtagt gacaacagga acagctctgc gtggcgaaat tattttagga
     1261 gaactcaaat attcttctgg gcctaataat agtttggcat cagtaacctt agcagataat
     1321 ttaaaaaaac tcggcttaga aattggcaga ttcaaaacag gaacgcctcc tcgtgtcaaa
     1381 gcatcttcta ttaattacga tcaaacggaa attcagccag gtgatgataa acctaatcat
     1441 ttttcattta tgtcaaaaga tgctgattac ctcaaagatc aaattccctg ctggttgact
     1501 tatactaatc aaactagtca tgatatcatt aatcagaacc tttacagagc accgatgttt
     1561 tctggcattg ttaaaggtgt aggccctcgt tactgcccat ctattgaaga taagattgtt
     1621 cgctttgctg ataaagaacg tcatcaactt ttcttagagc cagaggggcg tgatacagaa
     1681 gaagtgtatg ttcaagggtt gtcaacgagt cttccagaag atgtccaaaa agatttgatt
     1741 cattcgatca aaggacttga aaaggctgaa atgatgcgca ctggttatgc tattgaatat
     1801 gatattgttt tacctcacca gctacgtgcc acacttgaaa ccaagctaat ttcaggactc
     1861 tttacggctg ggcaaactaa tggaacttct gggtatgaag aggctgctgg ccaaggactt
     1921 attgctggaa tcaatgctgc tttgaaagtt caaggtaagc cagaacttat tttgaaacgg
     1981 agcgatgcct atattggcgt tatgattgac gatttggtta ccaaaggaac cttggaacct
     2041 tatcgattgt tgacatcgcg agctgagtat cgtttgattt tacgtcatga caacgctgat
     2101 atgcgtttga cagagattgg tcgcgacatt gggttggttg atgatgagcg ttggaaggcc
     2161 ttcgaaatta agaaaaacca atttgataac gaattaaaac gtctgaacag tatcaaatta
     2221 aaaccagtaa aagcaaccaa cgatcgtgtg caggaacttg gttttaaacc attgacggat
     2281 gctatgacag ctaaagaatt tatgcgtcgc ccagaaattg attatgcgac tgcagtctct
     2341 tttgttggtc ctgcggctga agatttagat gctaaaatca ttgaactttt agaaacagaa
     2401 atcaagtacg aaggctatat tcgcaaagct ttagatcagg ttgctaagat gaaacgcatg
     2461 gaagaaaaac gtattcctgc aaatattgat tgggatgcta ttgattctat tgcaactgag
     2521 gcgcgtcaga aatttaagaa aattaatcct gaaacaattg gacaagctag tcgtatttca
     2581 ggagtcaatc ctgcggacat cagtatcttg atgatttatt tagagggaaa cggaaaagct
     2641 catcgaaaat attaaatgga aatgaaattg taatctcaaa gcaagtggaa gctctgtatt
     2701 tcagggcttt tttatggtat aatgtgtgct taagaggtta taagatgaaa aaatttcgtt
     2761 ttgaaaccat tcatttgatt atgatgggat tgattttatt tggactactg gcactttgtg
     2821 tcagtattat gcaatcaaaa atattaatat tattagctat ttttctcgtt ttgctatttg
     2881 ttgttgctct tttatggtat caaaaagaag cttatcaatt atcagactta gctcatattg
     2941 agctcttaaa tgaacaaaca gaagataacc taaaaacgct acttgataat atgcctgttg
     3001 gagtagttca atttgatcaa gagaccaacg ctgtagaatg gtataatcct tatgcagaat
     3061 taatttttac aactgaagag ggttttatac aaaacagttt gattcagcaa attattacgg
     3121 aaaaacgtcg tgaagatatt tctcaaacat ttgaagtttc tggtaataaa tacacttctt
     3181 atattgatgt atcatcagga attttttatt tttttgatag ctttgtggga aacaggcaat
     3241 tagctgatgc tagtatgtta agaccggttg ttggcattat ttcggttgat aattatgatg
     3301 atatcactga tgatttatca gatgcagata cctcaaaaat taattcattt gtagctaact
     3361 tcattgatga gtttatggag tcaaaacgga ttttttaccg tcgtgttaat atggatcgct
     3421 actatttctt tacagacttt aaaacattaa atgatttgat ggataataaa ttttctgtct
     3481 tagaagagtt tcgtaaagaa gctcaagatg ctcagcgccc tttaacactc agcataggaa
     3541 tttcttttgg tgaagaaaat catagccaga ttggacaggt agctcttgag aatcttaata
     3601 ttgcgcttgt tcgtggtggt gatcagattg tcattcgtga aaatgcggat catacgaatc
     3661 caatttattt cgggggaggg tctgtttcta cagttaaacg ttcaagaaca cgtacccgtg
     3721 ctatgatgac agctatttca gatcgaatca agatggtgga caatgttttt attgttggac
     3781 ataggaaact tgatatggat gcactaggtt cagctgttgg tatgcaattt ttcgcaggta
     3841 acattattga aaatagtttt gccgtttaca atccagatga gatgagtcca gatattgaaa
     3901 gggctattga gcgattgcag gctgacggaa agactcgtct aatcagtgta tctcaagcaa
     3961 tgggtttagt gactccaaga tcacttttgg taatggttga ccattctaag atatctttaa
     4021 cactttctaa agaattttat gaacagtttc aaaatgttat tgtagttgat catcacagaa
     4081 gagatgatga ttttcctgat aatgctatct taacttttat tgaaagtgga gcaagtagtg
     4141 ctgcggagct cgtcactgag ttaattcaat ttcaaaatgc taaaaaacgt ttaaataaga
     4201 tccaagctag tgttttaatg gcaggtatta tgcttgatac taaaaatttt tctacgcgag
     4261 tgacaagtcg tacctttgat gtcgctagtt acttaagaag caaaggaagt gatagtgttg
     4321 aaattcaaaa tatatccgca acagattttg aagaatataa gcaaataaat gaaattattt
     4381 tacaaggaga acgtcttggt gacagtatca ttgtagctgc aggagaaaaa aatcatcttt
     4441 atagcaatgt tattgctagt aaagctgcag atacgatact gtcaatggct cacgttgagg
     4501 ctagctttgt attagttgaa acagcttctc ataagattgc tatttcagct agaagtcgta
     4561 gtaaaatcaa tgttcaacgt gtgatggaaa aattaggtgg aggaggccac tttaatcttg
     4621 ctgcctgtca gttaacggat atcagtcttc cccaagcgaa gcacttatta ttgaaaacta
     4681 ttaatatgac aatgaaagaa acaggagaag tagaatcatg aaagttattt ttttagcaga
     4741 tgtaaaagga aaaggtaaaa aaggagaaat caaagaggtc ccaacaggct atgctcaaaa
     4801 tttccttatt aagaaaaatt tagctaaaga agcaactagt caaagcatcg gtgaattaaa
     4861 aggaaaacaa aaagctgaag aaaaagctca agctgaaata ttagcagaag ctcaagctgt
     4921 caaggctgtt ttggatgagg acaaaacacg tgttcaattt caagaaaaag ttggcccaga
     4981 tggacgtaca tttggttcca tcacagctaa aaagatttca gaagaattgc aaaagcaatt
     5041 tggtgtgaaa gttgataaac gtcatattgt tttagatcat cctatccgcg ccattggtct
     5101 aattgaagtt cctgtgaaat tacataagga agtaacagct gagattaaat tggctatcac
     5161 agaagcataa tataaaaaac atcacaagat ttggaggtta tgaggttgcc tgaagtagct
     5221 gaattacgag ttcaacccca agatttacta gcagagcaat ctgttcttgg gtcaatcttt
     5281 atctcacctg ataagctgat tgcagtgaga gaatttatca gtccagacga tttttataag
     5341 tacgctcata aaattatctt tcgggcaatg attaccctca gcgatcgtaa tgatgccatt
     5401 gatgcaacca ctataagaac aatcctagat gatcaagatg atctgcaaag tattggtggc
     5461 ttatcctata ttgttgaact agttaatagt gtcccaacta gtgctaatgc agaatattat
     5521 gctaaaattg tagctgagaa agctatgttg cgtgatatta ttgctaggtt gacagaatct
     5581 gtcaacctag cttatgatga aattttaaaa ccagaagagg ttatcgctgg agttgagaga
     5641 gctttaattg aactcaatga acatagtaat cgtagtggat ttcgcaaaat ttcagatgtg
     5701 ctaaaagtta attacgaggc tttagaagca cgttctaagc agacttcaaa tgttacaggt
     5761 ttaccaactg gttttagaga ccttgacaag attacaacag gtttacaccc agatcaatta
     5821 gttattttag ctgctcggcc agcagtgggg aagactgcct ttgttcttaa tattgcgcaa
     5881 aatgtgggga ctaagcaaaa aaagactgtt gctatttttt ctttggaaat gggtgctgaa
     5941 agtttagtag atcgtatgct tgcagcagaa ggaatggttg attcgcacag tttaagaaca
     6001 gggcaactca cagatcagga ttggaataat gtaacaattg ctcagggagc tttggcagaa
     6061 gcaccgattt atattgacga tacgcccggg attaaaatta ctgaaatccg cgcaagatca
     6121 cggaaattgt ctcaagaagt ggatggtggt ttaggtctta tcgtaattga ctacttacag
     6181 ttgattacag gaactaaacc cgaaaatcgt cagcaagagg tttcagatat ttcaagacag
     6241 cttaaaatcc tagctaaaga attgaaagta ccagttattg ccctaagtca gctttctcgt
     6301 ggcgttgagc aaaggcaaga taaacgacca gttttatcag atattcgtga atcaggatct
     6361 attgagcagg atgccgatat tgtagccttc ttataccggg acgattatta ccgtaaagaa
     6421 ggtgatgatg ctgaagaagc tgttgaagat aacacaattg aagttatcct cgagaaaaat
     6481 agagctgggg cgcgtggaac agtcaaactg atgtttcaaa aagaatacaa caaattctca
     6541 agtatagccc agtttgaaga aagataagaa agagagacaa aaaatgagcg atgcatttac
     6601 agatgttgca aaaatgaaaa aaattaaaga ggacataaga gcccatgaag gacagttagt
     6661 agaattaacc cttgagaatg gacggaaacg ggaaaaaaat aaaattggta ggcttattga
     6721 ggtttacagt tcgctcttta tcattgagta tagtgatagc tctgatactc caggagcaat
     6781 tgataattct tatgtcgaat catacaccta ttcagatatt ttgacagaaa aaacattaat
     6841 tcgttattta gattgatttt tgcctcatag aggctttttc tttacaataa attgatataa
     6901 ttattagcga tagaagatta ttctgcctgt attcttttta ttttgaaaaa attcctataa
     6961 aagataatat ttttaggtta gattgaagga aaaaagaggt cttcaccatg gttaagcaaa
     7021 tgatcttagt actaaggtta aaagattatc gtgaaataaa gttttgacac aagtgtaatt
     7081 aatagaggaa cttgaagtat ccggtaaaac tatcttgaag tgaaaaaacg agtagacctc
     7141 ccctgataaa tacaatatac tagccatttc agagcaatta agagtttcca gtgaagtgct
     7201 tttgatagag agctaagaaa aaaacagtca aggtttaaga actgcaaatt agcatttaaa
     7261 ttattttttg ttaatgacag ttgtctttat taccataact ataacttctt ataatatagt
     7321 cttcttaatt catcagtggt ggttcgtccc atatctgacc ttaaaatatt aaactgatca
     7381 tcagatgata gatagactga ctttacaaaa caactttctt atggtaaact gttctttgtg
     7441 cgaaataaca gcagaaaaat atgaagctcg tcaacaggtg gttatctatt caagtaacct
     7501 ttgctgttta ggcgaaaccc ccctgcacga atcaggattt tttaaaccgt tatttcctca
     7561 aaaaatttag aggaggacat gtaatatgtc acgttatact ggtccatcat ggaaacaatc
     7621 acgtcgcctt ggtttatcac ttacaggcac aggtaaagaa ttggcacgtc gtaactacgt
     7681 tcctggtcaa cacggtccaa acaaccgtag caaactctca gaatatggtt tgcagttagc
     7741 tgagaaacaa aaacttcgtt tctcatacgg tttaggtgaa aaacaattcc gtaacttgtt
     7801 cgttcaagct acaaaaatca aagaaggaac tcttggtttc aactttatgg ttcttttaga
     7861 acgtcgtctt gacaacgttg tttaccgtct aggtttagca actactcgtc gtcaagcacg
     7921 tcaattcgtt aaccacggtc acatccttgt tgacggtaaa cgcgttgata tcccttcata
     7981 ccgtgttgat ccaggtcaag tgatttcagt tcgcgaaaaa tcaatgaaag tacctgcaat
     8041 ccttgaagct gttgaagcta ctcttggacg tccagctttc gtatcatttg atgctgaaaa
     8101 acttgaaggt tcattgactc gccttccaga acgcgatgaa attaacccag aaatcaatga
     8161 agcacttgtc gttgaattct ataacaaaat gctttaattt taagattaaa cttacaaaaa
     8221 gcctatttaa taggcttttt ttgtatctca taacaaatct attctgatcc cttcatttta
     8281 ctatggcttc taaaaaagtt atcactaagg ctgatgactt gtaaaatgat actttcgtaa
     8341 gggttactat ttaggtactc gtaagcattt tgagaacgaa ttgtgtcatt tcttgaggtg
     8401 attctttttt acctttagca atccaacttt gacagacacc aaaaaaagca tgggctaagt
     8461 agatacttcg gtattctttt tccgtttgag ataactcttc ggtgcggaac ttgtcctgta
     8521 aatcagtagt gatgagtagg cgaactttat tgatgataaa ggcctgtatt tctttggtac
     8581 cgttagcaga caaaagggaa gagagaagct gttctctttg gagaaattca aatacttcaa
     8641 ggaaggcttg ttctttattt tgatattttt tctcaaaaat atattctaat ttgtgaaaaa
     8701 aggtttgctg ataatagtca atcatttcat atttatcttt atagtgtgtg taaaaactag
     8761 agcgactaat tccagctctt ttagataatt taactgtggt aatatcgtca aaactttcgg
     8821 tttttagtaa cataaccatt gcttttaaaa ttgcttgctt cgtattttct ttacggttga
     8881 ccatctacca tctctccttt tgaacacttt tagacataat gtccaaaagt gaattttttt
     8941 ctcttgtaaa tttaaattt
//
LOCUS       DAUGUF010000044         8940 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUGUF010000044 DAUGUF010000000
VERSION     DAUGUF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8940
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.044"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..761)
                     /locus_tag="VIB71_001526"
     CDS             complement(<1..761)
                     /locus_tag="VIB71_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEQ8823253.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEGSAAPL
                     TSEQRQQEIEKIKQEIQAKYPKLTEEKYHSYGVFGRKYLDYDKYQKGLEEYTQEALKK
                     IVELIEKGATQGPAGPKGETGPAGPAGPEGKPGKAGEKGDRGEKGEAGIQGPQGEKGD
                     TGAQGPQGEAGAPGEKGEKGDRGETGAQGPVGPQGEKGETGAQGPQGEAGKPGEQGPQ
                     GEAGKPGEKAPEKSPEGEAGQPGEKAPEKSPEVTPT"
     gene            1143..1604
                     /gene="nrdI"
                     /locus_tag="VIB71_001527"
     CDS             1143..1604
                     /gene="nrdI"
                     /locus_tag="VIB71_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ8823254.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQHCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNS"
     gene            complement(1999..2817)
                     /locus_tag="VIB71_001528"
     CDS             complement(1999..2817)
                     /locus_tag="VIB71_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEQ8823255.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMADETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLNLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLDWR"
     gene            complement(2900..5086)
                     /locus_tag="VIB71_001529"
     CDS             complement(2900..5086)
                     /locus_tag="VIB71_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ8823256.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEILTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQATPTQVADSNSQVVQIINLLGGSGNIDDVDACMTRLRVTVKDP
                     AKVGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMSQLT
                     SKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIQSAERETTIVVAFTNTTEIQDVTLTSLGNQPAKTKVATVEL"
     gene            complement(5443..6192)
                     /locus_tag="VIB71_001530"
     CDS             complement(5443..6192)
                     /locus_tag="VIB71_001530"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEQ8823257.1"
                     /translation="MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLTDEAEVVLVFDDG
                     VKYLAKVTNSMAHELEIIEILPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPAEITQFEAAGAIK
                     VGLGPRIMRTETAPLYALSALSYALELQASK"
     gene            complement(6192..7145)
                     /locus_tag="VIB71_001531"
     CDS             complement(6192..7145)
                     /locus_tag="VIB71_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEQ8823258.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLETAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            complement(7216..7686)
                     /locus_tag="VIB71_001532"
     CDS             complement(7216..7686)
                     /locus_tag="VIB71_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEQ8823259.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEAASYPYPRY"
     gene            complement(7751..7972)
                     /locus_tag="VIB71_001533"
     CDS             complement(7751..7972)
                     /locus_tag="VIB71_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HEQ8823260.1"
                     /translation="MFDYIEGLIERRHSFIKEHFVASIDNFLNFREYRMLEGKGSISM
                     KFAKEKASREYVEFNKLQKINPDKGHKKI"
     gene            8162..8278
                     /locus_tag="VIB71_001534"
                     /pseudo
     CDS             8162..8278
                     /locus_tag="VIB71_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            8380..>8940
                     /locus_tag="VIB71_001535"
     CDS             8380..>8940
                     /locus_tag="VIB71_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISSpy2 family transposase"
                     /protein_id="HEQ8823261.1"
                     /translation="MSHLQYTAKSHHLQWNVTQLSTICHQLYRDYCPEGLKHRRNISL
                     SKVSDESLLVLPVLQAELGIKSQRHFYRICQLFPCGHLLERSRFNRRARQLIWLVQVI
                     RQAMNARISPDTIVIIDSFPLPLCQPVRNHRAHIFKGVADIGYNTSKHLWFYGFKVHM
                     LVTLSGYILNYVVTPASVHDIKAVHEL"
BASE COUNT         2412 a         2088 c         1739 g         2701 t
ORIGIN      
        1 gttggtgtca cttctgggct cttttctgga gctttttcgc ctggttggcc tgcttcgcct
       61 tctgggctct tttctggagc tttttcacct ggtttgcctg cttcaccttg tgggccttgc
      121 tcacctggtt tgcctgcttc accttgtggg ccttgtgcgc ccgtttcacc tttttcacct
      181 tgtgggccta ctggaccttg agctccagtt tcaccgcggt cacctttttc acccttttcg
      241 cctggagctc cagcttcacc ttgtgggcct tgagctccgg tgtcaccttt ttcaccttgt
      301 gggccttgga ttccagcttc acctttttca ccgcggtcgc ctttttctcc agctttacct
      361 ggcttacctt ctggaccggc tgggccagca ggaccagtct cacctttagg accggctggg
      421 ccttgtgttg cacctttttc aattaattct acaatttttt taagtgcttc ttgagtatac
      481 tcctctaatc ctttttgata tttatcgtaa tcaagatatt ttctgccaaa aactccataa
      541 ctgtggtatt tttcttcagt aagttttgga tatttagcct ggatttcctg tttaattttt
      601 tcaatttctt gttgtctctg ctccgatgtc agaggagcag ctgaaccctc agccttaacg
      661 ctgcttgccc cgcctccaaa ggctagaagg acggcagcgg ctgaggttag cccgtagcgc
      721 cagaccagtt tgttgagatt atggtgtttt gatgtcaaca tatgttgttc tctctttctc
      781 tattagatga tgtgttttag ataaaatatc atggtagcta gacctgatta tttataatag
      841 tattataata gagtgtgaaa acgattgtaa agttctcttt tgttgttcat cttttagatt
      901 ttgactgatt gctcttttgt ggagatcaga gggccacttt ggcacttgcc tgcctcgttt
      961 ttaagtcgag agcatccgga tcctttcttt aaggtcactc ttttttgaaa tgttactttt
     1021 tttgactgct tgtaccttct tgcctggttg aataccgcta ggtttcttct ttacttgttt
     1081 gttggtcttg attgtggtaa gcttatgaag aaaccttgta ggataaaaaa aaggagacac
     1141 ttatgcctca gattaccctt gtttttatta gcctcagtgg caacaccctt agctttgtca
     1201 agcgattatc cctttattta gcagacaatt acgattacca tgtcaaacag attaacatta
     1261 aagatttgaa gcacgagact tttcccgtca aagaagagtt tgtggcgatt ctacccactt
     1321 atctagaagg cggaaatggc gttgactctg gtgaagtgga gatcctcacc actcctttgg
     1381 gagagtttat tgctgcccat ggcaacgccc agcattgtct tgggattatt ggttcaggca
     1441 acaaaaactt taaccatcag tattgcctaa cagccaaaca gtatgccaaa cgctttggct
     1501 ttccactgct aggtgatttt gagctacgag ggactcctga tgacatttcc cggttagccc
     1561 aggtcatcat ggaggccagc tccagacact cgtctaacag ctagacagtc tatagatgat
     1621 catagctgtt ttaaaaaaga gcgcttttag gacaccaatt agggaagtcc cctaccctac
     1681 gccttgtgat ttcttagcct ttgaaaagag cgatcacagt gcttcttggg gcttgggatc
     1741 acaccaagca ctcctagaaa tacccccatg cagactttag caaggcaact gaacgcttgg
     1801 tggtactttc tgtgaagctc agatggttgg tgacaaaaaa agccctgttt ttctagggtt
     1861 actgacatga ctaaagaggt ctaaccagct ctatcttgag ctggttagac ctctttgtgt
     1921 tctcctaatc cccctagacg atcgcagttt cttatgtgtc ttggcttctc ctatgtggtg
     1981 tgcctgttag cacatgctct aacgccagtc taatgtcact tctagaccat agtggtcact
     2041 gacgactggc gcatccccgc cttcaaaggt aatcttagaa gaccggatga tgaagtcctt
     2101 actggtaaag acatggtcca ccttgagggc ttctttgtta ccttgccagc catcaatatc
     2161 agccacgatg ctatgatcac caaacacatg gtcagcaacc ttatggctat cttgtaggtt
     2221 tagggggcta cccatcatca cttgataacc gtcttgatcc gttggattgt taaaatctcc
     2281 cataagtagc aagggacagt ttagtgtgag cagctctttt tctaatttct cccactcccc
     2341 taaaaacccc ttgtcaaacc atgacaagtg cacattgaca acagcgactt ctttgccatc
     2401 taacgtggtt ttggctatga gtgagcgtct ggtgtggtag tctgtttcat cagccatcgc
     2461 tgacacgaga atatcggaaa catgaatagg ttgttttgat aagattgcca cgccttcctg
     2521 gtaaatgtca tagccaatat gattataagc ccaagaccaa taatagtgct gccctcgttt
     2581 ttgtaaataa tggatcaaga gcagggcaaa atgatcttta tgaatgcttg gtgtccctga
     2641 aagagcttga tatcttggta aatctgtggc cagctcgctc tcgattaact gattgatttc
     2701 ttgcaagcaa atgatatcgt atttttcagc taaaatatgc tcagccaaag caactagttt
     2761 tttaagagtg ttggcttgca tccacgaatg ggtattcagt gttaatacct tggtcattaa
     2821 tcctccttta taagacaaga agagccatag ggcctaaacc agctatggct attacctatc
     2881 actatctcgt gatgttttgt taaagttcta cggtggctac tttagtctta gcaggttgat
     2941 tgcctaaaga agtcaaggtc acatcttgga tctctgttgt gttggtaaaa gcaacaacaa
     3001 tggttgtttc acgctctgct gattggatgg cagcaagatc tgctacgact aataggtcac
     3061 ctgcatgaac ccgttgccct tctgagactt tgactgaaaa aggcacacca tttaaggcga
     3121 cggtatcaag tcccacgtgc accagcactt caagaccatt atctgtcagt aaaccaaagg
     3181 catgcttggt cggaaagaca ctggtcacaa ggccagctac gggtgcatag atattaccat
     3241 gggttggttc aaccgcaaac ccatctccca tcatcttagc agcaaacacc tggtctttca
     3301 cacctgtgat tgggagaacc atcccgtctg ccactgatag cacttcttct gtcacgtgtt
     3361 taaaatcttt tgcgggagtc ggtttgctag tgagctgtga catattgact tctggaataa
     3421 gagcacctga gtccagcaaa tcttgaatat ctgatttcaa aatatctgct ttagggccat
     3481 agaccgcttg aacgccgttg cctttttgga tcaagcccat agcgccagct tttttccaat
     3541 cgtcctcagc gccaacctta gcggggtctt tgaccgtcac tcgtaagcgc gtcatacaag
     3601 catcaacatc atcaatattg cctgacccac caaggagatt aatgatttgt acgacttgag
     3661 agttgctatc tgctacttgg gtcggtgttg cttgagtgtt acggtcaccc agtatatcgg
     3721 catcgtagtt acctaaacgg ccagctgttg cgagatgcat tttcttgatc atcatatccg
     3781 caataaagta catgataact gcaaagagga tagaaaccca aacaaagtta atcacatcca
     3841 tgcctaggcc tgctttaagg gccatagggg tacgggtcaa taattcaatg ttcccaaatg
     3901 agtgaacacg aaggttcaca aggtcagcca tggcaaatga agctccttga acaagggcat
     3961 agacgatgta aagtggcatt gctgcaaaca taaataggta ctcaagtggc tcagttaccc
     4021 ctgtcaaaaa gaccgctgcc gctgctgaga tgaacatcat tttgtatgtg tgttttttat
     4081 cggcatctac attacggtac atggctaagg caacccccat caatgttccg gtagctccaa
     4141 tcatttgtcc taccttaaag cgagctggag tcacactatc cattaagtga ctataggctg
     4201 aagcgtctga tcctttaagg tgaacaaggt cagttaccca agcaagccac aaagggtctt
     4261 gaccaaatac ttttgtcccc gctgctgcac ctgtcatgac ctcataagtt ccaccaagag
     4321 ctgtatagtt cattgggatc gtcaacatgt ggtgaagacc aaatggcaac aagagacgtt
     4381 ccaaggtacc atataggaat ggggctagga ttggagctga atcttgtgaa gaggcaatcc
     4441 acatcccaaa actgttaatc ccagactgga tcaccggcca aacaacaacc aaaataaggg
     4501 ctacaaaaat agaacgtaaa ataacaacaa atggtacaaa acgcttccca ttaaagaagg
     4561 tcaaaatttc aggaagttta cgataattat agtatttgtt ataggccgtt gctcctacga
     4621 accctgcaat aatcccaaca aaaacccctg tgtttaaagc tggagattcc aagacactgg
     4681 tgaaataatc tttaacgatc atttgagtgc caaggaggct tgtgattttt gcttctggat
     4741 cagctagcat agcactagac acgccataaa aagcacctgt tatccgattg atcaagacaa
     4801 aagcaagacc tgaggcaaag gcccctccag ctctttcttt agcccaacta ccaccaatgg
     4861 ccaaggcaaa tagcaagtga aggttaacaa taacagccca accaatttga gcgataatgt
     4921 tgcctagaga tgccaaaaat gctgagtcgt ggttaatcat tggaatagag tttccgatac
     4981 tgatcattaa accagccgct ggcataacag caataacgac cataagacat ttcccaaatt
     5041 tttgccaaaa ttcgaaacga aacagttgtt tgaatgatgt tttcattcta tctctccttt
     5101 attatcccct tttagccata gctgccctta aggcgctttt gtgacacaat gatatagact
     5161 acaactcagc gatgcaatcg cttgcattga tctgatacct ttattatact agcctcgcag
     5221 caatttgtaa agcgttttct tagacagatg ttagtcgttt ttcttcatta aatggtagtg
     5281 taacttacca aaaagaggac aagagcccat ttcctttttt ggtgatgagc ccatcaacgc
     5341 tcttcaaaaa aacaagaagc aataaaaaaa ggccgttgac acaatcgtga actgcctgtt
     5401 cgtttcttta gcctcttctt tctaaagtaa gcagcagctt acttattttg atgcctgcaa
     5461 ttccaaagca taactaagag cacttaaggc atatagcggc gctgtctctg ttcgcataat
     5521 gcgagggcct aagcccacct tgatggcacc tgctgcctca aactgagtga tttcagctgg
     5581 ggaaattccc ccttctggtc caaagataaa gaggattttt gcccctggct taacttcttt
     5641 tacttcacgc gccaaggtcg ctagctgacc tgccttagct gtttcctcat aagcaatgaa
     5701 gatatgatca aagctagaaa ggctttttag aaactctgct ttatgttcaa aaaggtgaac
     5761 ttcaggtacc ctatttcgtt tgctctgctc agccgctcct aatacaatct tagccaattt
     5821 gtcttctttt ttagctagtt ttttgccatc ccatttgact actgaccagt ctgcggggta
     5881 accccatagc gcactggctc ccaattcagt cactttctgg gcaatcgtgt ctaacttatc
     5941 gcctttagga aatccagaag caatagtcac tttaacaggc aattccacct gatctggcaa
     6001 gatctctata atctctaact catgagccat actattggtc accttggcta aatacttcac
     6061 cccatcatca aagaccaaga caacttcagc ctcgtcagtc aagcgcatca cttgaaacat
     6121 gtgcttgatg gtatctttat cggtaatcgt tacctttttt tctgctttgc ctttaataaa
     6181 atactgttgc attagccgcc aatcactcct gagatatcat ctgttttttt aaagacaagg
     6241 gcattccact caccttgaac catatgcgtc tcaaggaaga atcctgcgct aaaagcagtt
     6301 tccagaacca tatccaattt ctcagaaatg atgcctgata agataaggta accttccttt
     6361 ttgaccaaac ggtaagcatc atcagtcaat aagactaaga tatccgccaa gatattggct
     6421 acgatcacat ccgcttcttg gctaacccct tttaaaaggt cgccagcagc cacatgaatg
     6481 ttgtctgttc cttgattcaa atcaatgttt tcttgagcca ctcgaacagc cacgtcatct
     6541 aagtcataag cgtagatggt tttagcacct agtaaggaac tggcaatcga gaggacacct
     6601 gatccggtcc ctacatcgat aactgtctca ccaccacgaa ggacttgttc caaggcaaaa
     6661 aggctcatct tagttgtggg atgtgtccct gtcccaaatg ccattccagg atctaattta
     6721 atcacttttt ccccagcaga agcgtcataa tctgtccaac tagggacaat ggttaaatcg
     6781 tgcgtgatac gagctggttc atagtatttt ttccaattgt ctgcccagtc ttcctcagcc
     6841 aattcttgac tatccacagt aacctgacca acctgtaacc caaaactagc taactccgct
     6901 aactgttcat taatggtcgc aataacatcc gccaaattag tgctacttgg gtaataggct
     6961 gtgatagcta tcatgtcaga ctgctccaca tctgggtaca actccccaaa gcggtccttt
     7021 tgcccaatat agtctgcgct atccgcgata gcaacccctt gactgcctgt ctcaatcaac
     7081 acatgtgaaa cagcctcttg cgcatcacga tgcacatgaa ccgtcacttc ttgccatgtt
     7141 tccatagtta tgtcctttct attttgacct tttggttatt gtcctaatag tgttagcacc
     7201 atctcgtgtg tcaccttagt accttgggta agggtaactt gctgcttctt ctagtccttg
     7261 ttgaccttct tcaaaagctt gcgcgttcca ctccaagaag aaatcagcct tgctgtcatc
     7321 tgctaagaaa tccatcaaat cgctgtgccc ttcaatagca acatcgttga gaaattgcgc
     7381 aaagtaagct aagaattcac gagaaaagcc ctttttagcg tcaaaaggaa tggtaaccaa
     7441 ataatctgct gcatcaaatt gagacttggc agggttgtaa aagagcacat agtcctcaaa
     7501 aacaatatca tcttgggtca cttcgccact atcatcaatg gtttttatgg cctctttatt
     7561 ttgagcttct aacacaaaag tcacttcaac cgcatgattt ttcttgtccc aatccatagc
     7621 ataatcatat tgaaaatgct tgtccatttc ttcttctaat actgataaaa agccgtattt
     7681 tgccatcttt tttataccta atctttctaa ctgttgctgt ataaggcttt gtaagacctc
     7741 attagtttac ttaaattttt ttgtgtccct tatcagggtt aattttttgt aacttattaa
     7801 attctacata ctcacgacta gctttttctt ttgcgaattt catagaaata gagcctttac
     7861 cttctagcat tctatattca cggaaattaa gaaagttatc tatacttgca acaaaatgct
     7921 ccttaataaa tgaatgacgt ctctctatca aaccttcaat gtaatcaaag atggattatt
     7981 gcctttgaca atatgatcaa cactaatatt atagcacaaa ggagctaacg atgggtgctg
     8041 aagaacaact gaaagaattc catacgccaa tagccttgat ttgatgtata acgagcttta
     8101 ccagtttgat atagaatatc attcctttag acgtaaactc cttgaaataa gccgagaatg
     8161 cgccctagag gaattagacg ccatcaagac aagagactac gttcattggt ggaactatca
     8221 tcgcattcac agtagcctca gttaccaaac acatatgacc ttgagaaaca tcgcctaact
     8281 aaatatactt tactcgtggt gctagttaat gtcagaatac aataaaaagc ccaaaaggac
     8341 tatactgtaa gtgttcaaac aaacaggagg ttagccccaa tgagccactt acagtatacc
     8401 gctaaatccc atcacttaca atggaatgtc acacaattat ctacgatttg ccatcagcta
     8461 tatcgtgatt attgtccaga aggcttaaaa caccgtcgta acattagctt gtccaaggtc
     8521 tcagatgagt ctctactagt cttgcctgtc ttgcaagctg aattaggtat taagtcacaa
     8581 cggcattttt atcgtatctg tcaactcttt ccttgcggtc atctccttga aagaagtcgt
     8641 tttaatcgac gagcaagaca attaatttgg ttagtccaag tcattagaca agccatgaat
     8701 gctcgaattt ctcctgatac aatagtcatc atcgacagtt ttcctctacc actttgtcaa
     8761 cctgtccgta atcatagagc ccatattttt aaaggagtgg ctgatattgg ttataacacc
     8821 tctaagcacc tgtggttcta tgggttcaaa gtccacatgt tagtgacttt atcaggctat
     8881 attcttaact atgtggtcac accagcttct gttcatgata ttaaagcggt tcacgagtta
//
LOCUS       DAUGUF010000045         8922 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUGUF010000045 DAUGUF010000000
VERSION     DAUGUF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8922
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.045"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            87..1007
                     /gene="lmb"
                     /locus_tag="VIB71_001536"
     CDS             87..1007
                     /gene="lmb"
                     /locus_tag="VIB71_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEQ8823262.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1020..3491
                     /locus_tag="VIB71_001537"
     CDS             1020..3491
                     /locus_tag="VIB71_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEQ8823263.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNP
                     GQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGL
                     IFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDHSK
                     PSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHY
                     IGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVG
                     YMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLP
                     MHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHE
                     ESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETF
                     VWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQAD
                     KSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQP
                     EGVQFYNKNGELVTYDIKTLQQINP"
     gene            3660..3860
                     /locus_tag="VIB71_001538"
     CDS             3660..3860
                     /locus_tag="VIB71_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ8823264.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(3943..4569)
                     /locus_tag="VIB71_001539"
     CDS             complement(3943..4569)
                     /locus_tag="VIB71_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823265.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIVISHDFAMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4553..5356)
                     /locus_tag="VIB71_001540"
     CDS             complement(4553..5356)
                     /locus_tag="VIB71_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823266.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGDGEQLQTEFARCLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5368..6189)
                     /locus_tag="VIB71_001541"
     CDS             complement(5368..6189)
                     /locus_tag="VIB71_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823267.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6186..7163)
                     /locus_tag="VIB71_001542"
     CDS             complement(6186..7163)
                     /locus_tag="VIB71_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823268.1"
                     /translation="MKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQRQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            complement(7276..8904)
                     /locus_tag="VIB71_001543"
     CDS             complement(7276..8904)
                     /locus_tag="VIB71_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ8823269.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDEIV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNGKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         2924 a         1751 c         1774 g         2473 t
ORIGIN      
        1 agatggtagt tgccattgac aaagcattga taaaggagta aaattaactg gttaataact
       61 ggttaaatta taattgagga ggtactatga aaaaaggttt ttttctcatg gctatggtcg
      121 tgagtttagt aatgatagca gggtgtgata agtcagcaaa ccccaaacag cctacgcaag
      181 gcatgtcagt tgtaaccagc ttttacccaa tgtatgcgat gacaaaagaa gtatctggag
      241 acctcaatga tgtgaggatg atccaatcag gtgcaggcat tcattccttt gaaccgtctg
      301 taaatgatgt ggcagctatt tatgacgcgg atttgtttgt ttaccattca cataccttag
      361 aagcttgggc aagggatcta gaccctaatt taaaaaaatc aaaggttgat gtgtttgaag
      421 cgtcaaaacc tctgacacta gatagagtca aagggctaga agatatggaa gtcacacaag
      481 gcattgaccc tgcgacactt tatgacccac atacctggac agatcccgtt ttagctggtg
      541 aggaagctgt taatatcgct aaagagctag gacgtttgga tcctaaacac aaagacagtt
      601 acactaaaaa tgctaaggct ttcaaaaaag aagcagagca actaactgaa gaatacactc
      661 aaaaatttaa aaaggtgcgc tcaaaaacat tcgtgacgca acacacggca ttttcttatc
      721 tggctaaacg attcggcttg aaacaacttg gtatctcggg tatttctcca gagcaagagc
      781 cctctcctcg ccaattgaaa gaaattcaag actttgtcaa agaatacaac gtcaagacta
      841 tttttgcaga agacaatgtc aatcccaaaa ttgctcatgc tattgcgaaa tcaacaggag
      901 ctaaagtaaa gacattaagt ccacttgaag ctgctccaag cggaaacaag acatatctag
      961 aaaatcttag agcaaatttg gaagtgctct atcaacagtt gaagtaaagg agattattag
     1021 tgaagaaaac atatggttat atcggttcag ttgctgccat tttactagct actcatattg
     1081 gaagttacca acttggtaag catcatatgg gtctagcaac aaaggacaat cagattgcct
     1141 atattgatga tagcaaaggt aaggcaaaag cccctaaaac aaacaaaacg atggatcaaa
     1201 tcagtgctga agaaggcatc tctgctgaac agatcgtagt caaaattact gaccaaggtt
     1261 atgtgacctc acacggtgac cattatcatt tttacaatgg gaaagttcct tatgatgcga
     1321 ttattagtga agagttgttg atgacggatc ctaattaccg ttttaaacaa tcagacgtta
     1381 tcaatgaaat cttagacggt tacgttatta aagtcaatgg caactattat gtttacctca
     1441 agccaggtag taagcgcaaa aacattcgaa ccaaacaaca aattgctgag caagtagcca
     1501 aaggaactaa agaagctaaa gaaaaaggtt tagctcaagt ggcccatctc agtaaagaag
     1561 aagttgcggc agtcaatgaa gcaaaaagac aaggacgcta tactacagac gatggctata
     1621 tttttagtcc gacagatatc attgatgatt taggagatgc ttatttagta cctcatggta
     1681 atcactatca ttatattcct aaaaaggatt tgtctccaag tgagctagct gctgcacaag
     1741 cctactggag tcaaaaacaa ggtcgaggtg ctagaccgtc tgattaccgc ccgacaccag
     1801 ccccaggtcg taggaaagcc ccaattcctg atgtgacgcc taaccctgga caaggtcatc
     1861 agccagataa cggtggctat catccagcgc ctcctaggcc aaatgatgcg tcacaaaaca
     1921 aacaccaaag agatgagttt aaaggaaaaa cctttaagga acttttagat caactacacc
     1981 gtcttgattt gaaataccgt catgtggaag aagatgggtt gatttttgaa ccgactcaag
     2041 tgatcaaatc aaacgctttt ggatatgtgg tgcctcatgg agatcattat catattatcc
     2101 caagaagtca gttatcacct cttgaaatgg aattagcaga tcgatactta gccggccaaa
     2161 ctgaggacaa tgactcaggt tcagatcact caaaaccatc agataaagaa gtgacacata
     2221 cctttcttgg tcatcgcatc aaagcttacg gaaaaggctt agatggtaaa ccatatgata
     2281 cgagtgatgc ttatgttttt agtaaagaat ccattcattc agtggataaa tcaggagtta
     2341 cagctaaaca cggagatcat ttccactata taggatttgg agaacttgaa caatatgagt
     2401 tggatgaggt cgctaactgg gtgaaagcaa aaggtcaagc tgatgagctt gctgctgctt
     2461 tggatcagga acaaggcaaa gaaaaaccac tctttgacac taaaaaagtg agtcgcaaag
     2521 taacaaaaga tggtaaagtg ggctatatga tgccaaaaga tggcaaggac tatttctatg
     2581 ctcgtgatca acttgatttg actcagattg cctttgccga acaagaacta atgcttaaag
     2641 ataagaaaca ttaccgttat gacattgttg acacaggtat tgagccacga cttgctgtag
     2701 atgtgtcaag tctgccgatg catgctggta atgctactta cgatactgga agttcgtttg
     2761 ttatccctca tattgatcat atccatgtcg ttccgtattc atggttgacg cgcgatcaga
     2821 ttgcaacaat caagtatgtg atgcaacacc ccgaagttcg tccggatgta tggtctaagc
     2881 cagggcatga agagtcaggt tcggtcattc caaatgttac gcctcttgat aaacgtgctg
     2941 gtatgccaaa ctggcaaatt atccattctg ctgaagaagt tcaaaaagcc ctagcagaag
     3001 gtcgttttgc aacaccagac ggctatattt tcgatccacg agatgttttg gcaaaagaaa
     3061 cttttgtatg gaaagatggc tcctttagca tcccaagagc agatggcagt tcattgagaa
     3121 ccattaataa atctgatcta tcccaagctg agtggcaaca agctcaagag ttattggcaa
     3181 agaaaaacgc tggtgatgct actgatacgg ataaacccaa agaaaagcaa caggcagata
     3241 agagcaatga aaaccaacag ccaagtgaag ccagtaaaga agaagaaaaa gaatcagatg
     3301 actttataga cagtttacca gactatggtc tagatagagc aaccctagaa gatcatatca
     3361 atcaattagc acaaaaagct aatatcgatc ctaagtatct cattttccaa ccagaaggtg
     3421 tccaatttta taataaaaat ggtgaattgg taacttatga tatcaagaca cttcaacaaa
     3481 taaaccctta accaaaagaa gatctcattg ttaaagcact gctttgtcaa agcaagttac
     3541 ggtgattttg aagtcatttt atgtaacgag tagtgataaa agttggataa tagcggtttt
     3601 cttttgcaaa gaaatggtat ccatgttaga ataataaaaa aaagaggagg attctaatca
     3661 tgtcagaaga aaaattaaaa tcaaaaattg agcaagcatc tggtggccta aaagaaggtg
     3721 ctggtaagtt gacaggtgat aaagagctag aagcaaaagg atttgttgaa aaaacaattg
     3781 ctaaaggcaa agaacttgca gacgatgcaa aagaagcggt tgaaggtgct gtagatgccg
     3841 ttaaggaaaa attaaaataa ttaaaaaaaa ccagctgtaa gctggttttt ttaatggtgt
     3901 gattttgtta ggaaaagact caataggtaa taaccgtagg tgttaggtat gcttgaacag
     3961 ttgagtacga ttctcttcaa tcatatagca cgcgtcacaa agtttttcta acatagcaaa
     4021 atcatgacta ataacgatga gacctaaatt tctatccttt acaatctcta acaggctttt
     4081 ccatacacta gcttgtgtaa tgctatccaa catagtagtc atttcatctg caataaggta
     4141 tttcgtctct ggatgtaatg aacgcacaat cgaaaagcgt tgcaattccc ctcccgagag
     4201 ttcactaggg cgacgcttta gccatttttc ttgaatgcca aaagcatctc gcaaatcttg
     4261 acttggatag taggcttctt ccaaactttt tttcataggc cataaaggat tcatggtttg
     4321 ttcaggatgt tgttggataa gttgtacagg tctaaatgct ttgttaggca aatgactgcc
     4381 atcaactaat acttcaccag atttaggctg caaaaaaccg gcaagcactc tggataaact
     4441 cgtttttcca cacccacttt gtccaaatat ccctaagatt tgaccaggtg ctacctctaa
     4501 atcaatctcc ttaaaaagcc attgatcttt tttatgataa aagccaagct ttttagcctc
     4561 taaggtcatg agtaactcct ttcaaaaagt cttgctgagg gagtgtgcgc cataaacatc
     4621 tcgcaaattc cgtttgtaat tgctccccat ctccgctaaa aaagctagct ggggctgttt
     4681 caatagcttt tccctcttta aaaatagtta tacgatccgc aatttgacta gctgctacaa
     4741 tatcatgagt gataaatatg acgcttattc ctttatctgc aaaggagcgt agttgatcta
     4801 aaaccatttg cagagcatct ggatgtaatc caggggtagg ctcatccgca ataatcaaag
     4861 aaaccgtatc actaatacac gttgtaaaca aaacacgtcg gagcattccg ccagaaagtt
     4921 ggaaaggata caagtcacca tcactttctt ttaaaccaaa ctgttgaaac aatccttctt
     4981 gagtagcctt agcattttct gagataccca agcgcacctg atgcttgact ttcatagatg
     5041 gatctaaata attaacggat tgtggaatca acgtcatttc ttttcctcgc aactgtttga
     5101 tgcgtttaga agttagtgat tgaccacgat aaatcatatc tcctgttaca gctgcatttt
     5161 taggaagaat atccataata gcatgtgcta ataaactctt gcctgaacca ctagcaccta
     5221 taatagctaa taactcacct tttttaactt ctaaattcag cgcttggatc ggtgtggatt
     5281 gaaatggttt taaaaatctt ccgtattgag tgaaggtgat ggagaggtct ttaatgctta
     5341 ataatgtttc tgtcatatct ctacctccta aaaatgatcc gtctgagggt aaaagagttt
     5401 ctttaaagat tctccgatag tatcaaaggc attgacaacc aaaataagat aaaggcctgg
     5461 aaaaatcacc aaccaccaat tgccaagaga gatatgctta gctgcctctg acaaaatgat
     5521 accaaccgaa ggttgttcgg cagaaaggcc aaatcctaag aaagtcatgg atgcttcatg
     5581 caagatgacg tgcggaaata agaggataaa cccaatgaaa atttgagaag caatcaaagg
     5641 caggatatga tgcctcacaa tataataagg cgtttttccc atgcttttag agagctggac
     5701 aaaggcttta ttctttagat catagacttc attgcggata agccttgcta gagagggcca
     5761 atgggtaaca gctgttgcaa tgataacccc ttgagcccct ttcccaacaa caaaagaaat
     5821 gagaatcata aaaatcaaat gaggcatacc aataaacaaa tcaactaacc atgctattat
     5881 tttatcaata aggctatttc ctaaacctgc aagcactcca aaaacggtcg caagaaagac
     5941 tcccataagg gcacctaata agccgacttg taaagagaaa taaagccctt taatcgttct
     6001 gacaaacata tccctaccta aaccatctgt cccaaaaaga tggtttaagg aaggggcgag
     6061 gttgcgtaaa gctgcattgg tttccaaagg cgtcctatag aaataaaggt ttaaggctag
     6121 aatactaaga atgagagaaa tggcgatacc tagttgccat aaaaccatcg ttcgacgttt
     6181 caatatcata cttttctcct taactgtgga ttgatgatgc tatttaaaat gtccgcaata
     6241 agattgcccg caaaaacaaa taatgtccct atcatcacga tagctagaag tagcggtgta
     6301 tcacttttaa gtcctgcttc agtgagggta gaccctaagc caggatatga gaaaacttgc
     6361 tcagcaagaa cagatcctcc aaacaattct ccaaaatagg aaaaatgcag tgtaatagct
     6421 ggtacgatag catttctaag acaatgattt ttaaaaattt gccgctgtgt ttccccacgc
     6481 gctctggcaa ataagacata ttcactagaa agcaccgaca tcattttagt tctcgtatga
     6541 agagtgacat tggcaatgcc tagaatactt agcgtgaaaa caggtaacat aaggtgctta
     6601 acccgatcag ctaacgtaat atcttgactc aaagtcccaa tcggggaaga aataccaatc
     6661 gggaaccacc ccagctggac agaaaagatt aataaaaaaa tgaggccaat ccaaaacgtt
     6721 ggtactgata tctgaaggta agaaaaccac ctgacaactc ggtcaagtaa tttcccttga
     6781 tggaaagcgg ataacgttcc taagataaat ccaataagac ccgataagat ccaagagagt
     6841 cccataagta tgaaagaagc acctgcccgt gatctaataa tatcactaac aggttgccga
     6901 taaacgagcg aggtccctaa atgtccctgt atcacatttt tcaaccaaat aaaatattgg
     6961 actagagctg gcttatccaa gccatagtgg tgagcaatcg ctttgtactg agcaggggtt
     7021 agtgatgtgt cataattgac acttgccatg acgggatcta ctggagattg ttttaacaaa
     7081 acgaaggtca aaacagatac cccaaaaata agtgtgatac atctgatgat tttccagatg
     7141 ataataatgg tagtacgttt cacaatgaaa tctccttaat cgataagaaa aggagccgag
     7201 gaaacgatca gcacagtttt gtgtatcttg ttttctcaga ctccaaactt aaagtcgctg
     7261 tattaactaa acgcgttact tagttgattc atcccaagtc cactcggcaa tgttagtcaa
     7321 taatgaccaa tcatgaccat gactgtggac gccttgttta cctacattga tacgtttatc
     7381 accaatataa gtatggttaa ggctcaccaa ccatacattt ggcaaatctc caagagtaga
     7441 agcacctgtt ttgccatccc actgcgctaa cttccaatat tcgttagctt tgtcaaggtc
     7501 agaagatgtc attgctttgt caaggtactt agtcacggta ggattgttat aaaacgtaat
     7561 attggtccaa cctttacctg ctaggcttgg atgatgtgat tcataaaatt gctgcgcgtg
     7621 atgacgtcct ccggcataaa gtaaggctga gtcatgtgac ttcgttgcca tttcatccca
     7681 gttactagct ttgagtttaa tagtaatccc tagggctttg gcttgctctg ctacttcaac
     7741 ggctaagttc gctcgcaatt gatcattagt agggtagtac agatcaaacg ctgcatcaag
     7801 gtcacctttt ttacggctac cgtctgcttg ttctttccat cccgcttttg tcaacaattg
     7861 cttagcttta gctactttat tatctttaat ggctgttttt ggattccaaa atggtgtttt
     7921 atcaataatt gaataagctg gtttaccata accatttaaa accgtatcga gaactttttg
     7981 tctatttaaa ccaatagtca aggctttgcg gattgctgga tcgctagtga catcatttcc
     8041 tacaggataa ccatcaggag aatcagtgat gacgcctttt ttcacataag gtaatgataa
     8101 gccgcgcaca tcatttgatg gaatgtcaag gaggcgagtg cctttgactt tcttactagc
     8161 aagttctggt gtcgcgtaga tcatatcaac atcaccagat tctaaagcag ctagtgctgt
     8221 gttttcatca agtaagaccc aagtccactt tttaaagtat ggttttttcc catgccaata
     8281 agggttacga acaaaaatag cttgttctcc agccttatat tcttttacca tgtaaggtcc
     8341 tgaaccgata ggattgctct tatacttacc attgtaatgt tttttaggga cgattgggat
     8401 ttcagtcaac tgtgctgtaa atgtcgaatg cgcctcagtc aaatggatat tgacctgatt
     8461 tttcccaact acttcaacgt tcttgatgaa ggttagatcc caagcctttc catctgcttt
     8521 caacatatca taagtaaact taacatcatc agcagtaaca ggctcaccat ttgagaattt
     8581 aaaatcatca tgcaagtcaa acgaccaagt cagcccatct tcagagagat ggtatgtttt
     8641 agcaagctct ccttttatat ctagttcagg agaacgtttc aatagagtgc tatgagtgat
     8701 attcccttca ttgtggactc cataacggtc ctttggatcg aattcatgag ggagctttgc
     8761 ccccatagaa acgacaattt cgtcttttgg acgttgtttg cgctgacgtt cttttgtttg
     8821 gggcttttgt tgttgacatg caactaaaat aagcccagtc aaaaataacg tgataataga
     8881 gaagtatttt aggtattttg acacaatcaa atctccttat tt
//
LOCUS       DAUGUF010000046         8697 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUGUF010000046 DAUGUF010000000
VERSION     DAUGUF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8697
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.046"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            134..295
                     /gene="sagA"
                     /locus_tag="VIB71_001544"
     CDS             134..295
                     /gene="sagA"
                     /locus_tag="VIB71_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEQ8823270.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            517..1467
                     /gene="sagB"
                     /locus_tag="VIB71_001545"
     CDS             517..1467
                     /gene="sagB"
                     /locus_tag="VIB71_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEQ8823271.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYIKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1464..2522
                     /locus_tag="VIB71_001546"
     CDS             1464..2522
                     /locus_tag="VIB71_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEQ8823272.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNDPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2542..3900
                     /locus_tag="VIB71_001547"
     CDS             2542..3900
                     /locus_tag="VIB71_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEQ8823273.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3875..4546
                     /locus_tag="VIB71_001548"
     CDS             3875..4546
                     /locus_tag="VIB71_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ8823274.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWYLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4543..5226
                     /locus_tag="VIB71_001549"
     CDS             4543..5226
                     /locus_tag="VIB71_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEQ8823275.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLVALSYQDFLDV
                     LLSLFQFVIIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5249..6172
                     /locus_tag="VIB71_001550"
     CDS             5249..6172
                     /locus_tag="VIB71_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823276.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6181..7308
                     /locus_tag="VIB71_001551"
     CDS             6181..7308
                     /locus_tag="VIB71_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823277.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILSLIGMRKQVTT"
     gene            7305..8423
                     /locus_tag="VIB71_001552"
     CDS             7305..8423
                     /locus_tag="VIB71_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823278.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGETLSQAWPYLLALMGTALALISFSSLLLKPTKL"
BASE COUNT         2722 a         1335 c         1639 g         3001 t
ORIGIN      
        1 gatagttgtt gtgttacaac agtacaattg agctagcctt gtccttgttg tgttaacttt
       61 atttttaaaa taaggttaaa aataaacgac tcgtgttctt atcagttact tattagataa
      121 ggaggtaaac cttatgttaa aatttacttc aaatatttta gctactagtg tagctgaaac
      181 aactcaagtt gctcctggag gctgctgttg ctgctgtact acttgttgct tctcaattgc
      241 tactggaagt ggtaattctc aaggtggtag cggaagttat acgccaggta aataatctat
      301 ttagcatctc tatgtgatag tgatattaag gtaatgagtt tgctagcaac taagttatct
      361 ttggtaactt ctgattatag atgaatggca tagaggtgtt agaaaacatg agacaaaagt
      421 aatcttcttg atgctaacgt ctcaggtaat tagcaggtac tagacagtac ctgctaatta
      481 ctatatgttt agtaaaatga gataggaaag atagttatgt cattttttac aaaggaacaa
      541 caacctaaag agaattgtcc gccaataact gttgaaaaag caaggcaatt gtttgaattt
      601 aatacaaacc acttgtcctt atcggattac catcatcaaa cggtgctaaa aacatcaaag
      661 cagctagttg ctcaacattt aatgcctaat gcaaccgata atcttagtca acattttttg
      721 atgaactata aagctaataa taattattta ggcttccaag ctagtattgt cgactttttt
      781 acagattctg ccgttgctaa tttttcaagt agttacgttt atgaaagtca ggaaaagata
      841 attcgtttac caaaacctac caagatatca actgctctgt cgacatgtat tataaaacga
      901 agaagtcatc gtcaattttc agatagacaa atgcctcttc aagatttatc aaacattctt
      961 tattatgcat gcggtgttag ttcacaagca tcaattagag atggagcatc agataagatt
     1021 acactcagaa actgtgcttc aggtggaggt ttatacccta ttcatttagt tttttatgct
     1081 agaaacatca gtaaattaat agatggtttc tatgaatatc taccctatca gcatgcacta
     1141 aggtgttatc ggcatagctc tgaggaaaac gttagagatt ttgcggaata cggtgctatt
     1201 aatgctgaaa attgtaatat tattattatt tatgtctacc attacataaa aaatacacgt
     1261 aaatatggga atcaggcgac tgcctatgct tttattgaat caggagaaat agcccagaat
     1321 attcaattga ctgcaactgc cttaacttat ggaagtattg atattggtgg ttataataag
     1381 gaatatctcc aagaattatt agatttagat gggctaggag agcatgtgat tcacatgaca
     1441 ctcgtaggaa ctaaggagtc tcaatgaaat atcaacttaa tagtaatgtt cgtgtcgtga
     1501 catttcaaga tacattttgt tttagaaaag gaatctggga ctttaatgaa gccattctag
     1561 atttgacaca agaacctcaa aatttaaaga tagtttatca agaaatagtt tcacagttgg
     1621 ttaagggagt agccattgat actgaaactt atgaaaatac tttagaacct gagacgttcg
     1681 ctaatttaat ggaagtcatt tcaggcttgt attacaatga tatgctgatg cttgaggatg
     1741 actacaatct tgaagaaaat gtcatgaaaa ttttaatggg taatttccgt tttatggcgc
     1801 aagcaggtca tatggtaagc aatgatcctg ttttgtttat cagtgattcg acttatgtta
     1861 atgaatctgc tgagttgcta gctgaacaac tgcatttaca attgcaagtg gctagcgatg
     1921 acttaaaaat gttaattcag cagacagatg ttagttcgcg tttagatgct ttggagcatc
     1981 gccgtaacat gaattgttta tcagaagcct tgtgcgatta ccaaagtatt attatttgtc
     2041 aagaacgctt gaatattatg atgttgcgac acttgaatga agttagcgta gctatgaaaa
     2101 aacaattagt gattggtttt gtagatggac cattcttgca cacttgtact ttgaatcctc
     2161 ctcatagtgc tgactttgat agcttagaaa gaagagtttt ggcacgttta caagactcaa
     2221 ctctctatca acattttgct aatcagattt taccagcaac acaagatgtg agccaggcct
     2281 atttaccatt gttaaatgtt ttaatgaatt tagtcgttag cgaagctttc attattgctc
     2341 aaacaggtag ttctaaattt gagggacgtt tattaagcat ttacttaccg acgcttgaga
     2401 ttcaggtcca agatattttg aaaatgtcta attcacagac acaaggagct ttggcaaaat
     2461 taaaatatga ggatcagcag atatcaacac gtgagattgt taaaaaactc cttgacgagt
     2521 aacctataag gagaatctat tatgttatac tattatcctt cttttaatca tatttttgat
     2581 gaattaaaaa gtttaagtgg caatcgaaca ggtatcttaa atcaatctca agttccagtt
     2641 tgcaaccatc ctcacgatgt ttacttaaaa agtattactg gccaaatgcc agattatcat
     2701 aaacaattta taggtgagtt gagtcaagtt agttatcaca ttattggtta cggcagttac
     2761 tatgaagaag cacttatcaa gtatttagga gaaagtattg aacgctatgc tactgtaatt
     2821 gccggagact tactatcaga tcggattgtc tatgcttctt ataatgagtt aaaactgtta
     2881 cataaagtga tgcctttaga atacttgcaa gtgtttactc aagaacagat cgcattatct
     2941 tgtgacttgc aaatgatgat gtgcgataaa atggtaactg agaacgatgt attgggctgg
     3001 gttaaatgtc ccatgttctt tgaggacgca gagatgtatg ttccagctca aatgctttgt
     3061 gttgggtata aaacaaatga gactgtagga gaaagacgga taataccagg attttctacg
     3121 ggaacagctt ctcacaaaac gttagaagcg gctatgtgca acagtttgat tgaatacatc
     3181 cagatcgatt caatgatgct tagctggtat actaagaagc cttgccccaa gattattgtt
     3241 gatgatcctg atattgaagt gattttagaa gaagctagac tgggaaaaga cagtctatac
     3301 gacattattc ctatcgatat gactgtagga gaagataatc ctctttatac gtttggaatc
     3361 attctcaaaa ataaatatga tgaagggcct tacctcttgt ttggagtgca ggctgggtta
     3421 gatcctaaac atgctttgct aagagggatc atggaagctt cagctatcag ctatagttac
     3481 tactataatc ttttatatca aaaagcttcc cttgcaaata ttgaatgcga agaacctttg
     3541 tttttagatt tagatagtaa tgttttctat tatgcacatc ccaaggacca agaccataaa
     3601 tggaaggcct ttgaaccttt gatttcagga gaagttctgt taagtgattt ggaagatcat
     3661 tctggtaaag ataaaaaaga agatttgaag actttattag cttatgctaa gaaagtcagt
     3721 cctaatgctg tctttttaga tattacacct cctgaagctc tagaaaaagg ctggtacgtc
     3781 acgcgagttc tgatgccaga acttcttgaa atgtgtatac cagcatttcc ttttgctaat
     3841 cacccacgaa tgagacagtt tggaggtgta acaaatgcct ttgtccatcc aatgccttaa
     3901 tctttgtttt ttgttggtaa ctttttgtcc ttcaattcct atgcaagcta tttttggaaa
     3961 agaagatagt ggttatgcat ttaatttaat tggttttcta agagcaactc tgatttatga
     4021 cattttggct ttggtaagta tttatgtttt gtcacctcaa ataaccttgt ctcttgaaag
     4081 tattgatagt aagacgttct ttatgggact tgtattttgc gtcttgatag tactgattga
     4141 actcgttttc ttacatggtt tacgttgttg gcaaaaaaag caatggcttc ctgcaacttt
     4201 ctcgtttgta ggaacgacaa atgattggtc taagattggc tatcctttat tactagcttt
     4261 atttgaagag acgatttatc gttttttgtg gtttaatata ttagcttttc aatggtattt
     4321 accaacaatt attgttttaa ttgtaactag tttttgctat gctttaaatc acttattgat
     4381 ggggaaatcc attttttatg ctaagttggt aacaggcatc atttatggta gtatttacat
     4441 gctgactagt caattgtggt tggttgtgat aatgcatgta ggagggaact tgctagttga
     4501 gtgtcttagc catcttcaaa caaaaaagaa gaaggaggtg acatgatgct attggttttg
     4561 ctgtcgtttt taggtctaac tactctttgg ttgaccagtt atcgaagacg ttgtttggct
     4621 agatggcatc ttcaatggtt agtggcctta tcctatcaag attttttaga tgtcttactg
     4681 agtctgtttc aatttgtcat tattatactt gttttattct tttactcagc tactattaat
     4741 ctaggagagg ttctgacctt tttgacacaa actagctggc attggcagat tctttgttat
     4801 ttagtgttgt atcttatggc catcatagag atgacgcttt tagttttaat tcttatcttt
     4861 gatgttttgc tccagaaaga tagtcgattg ctctttaaaa aaataacttg gctgcctttt
     4921 agacaagata aaccagtctt aagtatactt ttgctaggca tagttattct agtagacagt
     4981 ctcttttatt tgggcttgct tatattatta ggagaacagt cgctaacaag tttagcaacg
     5041 cttattttag gctatgggat agtcaaggct tgtcgctatt caggttggtt aaatgtacta
     5101 ttagcttttt gtcttttcac tatagttgga ctatgggcag ttacggcaac tttattatat
     5161 ggttggctag taggtgcgat gatattaacg gtgacttatt tgatgattag ttgcaaagag
     5221 tattagcaat attaaaaagg agtgatatat gagttttgta caattaacaa atgttgtcaa
     5281 gtcctacaaa aacggcaaga aagctgtcaa tgatgtttcc ttgtctattg aagcaggtaa
     5341 tatttatggt ttgttaggac caaatggtgc tggtaagtct accttgatta atcttatctt
     5401 aggcttgatc cctttgagtt ctggtaaaat tactgtttta gggcaatccc aaaagactat
     5461 tcgaaaaata agttcgcaga taggttatgt tcctcaagac attgctgttt atccagacct
     5521 aactgcttat gaaaatgtag aactatttgg gtcactttat ggcttaaagg gagctcagct
     5581 taaaaaacaa gttctaaaaa gtttagaatt tgtggggcta cactcccaag ctaagcagtt
     5641 tccaagtcaa ttctcaggag gaatgaagag acggttaaat atcgcttgtg cgctagttca
     5701 ttcacctaaa ttaatcattt ttgacgaacc gactgtaggg attgatcctc aatcacgtaa
     5761 tcatatttta gagtcgattc gtttgctaaa caaagaaggt gccacagtta tttatacgac
     5821 ccattatatg gaagaagtag aggctctttg tgattatatt tttattatgg atcatggtca
     5881 agttattgaa gaaggaccta aatttgaact ggaaaaacgt tacgttgcaa atctagcaaa
     5941 ccagattatt gtaactctaa cagattcacg tcatttggaa ctggcagata agcctgattg
     6001 gtctttgata gaagatggag aaaaactcat gttgaagatt gataatagtg atatgacatc
     6061 agttgttcat cagctcacac aggccaatat tacttttagc gagattagac ataaccattt
     6121 gaatttagaa gaaattttct tacacttaac aggtaagaag ttacgagatt agaggttact
     6181 atggttttat ttcatttaat caaaaaagaa agtttacaga tttttagaaa ccgaacagcc
     6241 ttattaatga tggtgatttt tccaattttg atgatcgtta ttttaagttt tgcctttaaa
     6301 tcaagtttta atactgcgac aacagtccct aaattgacca ttcgttacca attagagggt
     6361 gaaaaaacgg attaccagaa aaattttctt gcttttttaa aagttttaaa ccaaaaactt
     6421 catttagagg ctaaacctag taattctctt gaaaaagatc gacaaagggt cagtgaagga
     6481 gccttaacgg ctgttttaga agtgaagaag aatcagacca ttaaggttat tactaataat
     6541 attaatcagc aaaatgcaga tttaatcaat atgctagtaa aaaattatgt agataatgct
     6601 aaaacttatg actcgatagc agctctttat cctcaacaat taaatcatat cagaaagcga
     6661 agtgtggact atgttaaggt cagttcaata cagacaagta aaggaatgac atcagctgat
     6721 tattatgcta tttccatgtt taccatgatt actttttata gtatgatgtc tgcgatgaac
     6781 cttgttttgt cagatcgtca acaacggatt acaaatcgta ttcacttaac aggagtttct
     6841 ccaagtcttt tggtctttgg aaaattaata ggtgctatgt tagcaacaac tgttcaattg
     6901 agtcttttat acatttttac aaggtttgtt ttacgagtta attggggcac taatgagtgg
     6961 atgcttattg gtataacagc ctccttagtc tatctctctg tagctatagg tatcgggcta
     7021 ggcataagca ttaaaaatga ggctttttta acggttgcat ccaatactat tattcctata
     7081 ttcgcctttt taggaggcag ttacgttcca ttgacaacat tacacagctc tattattaat
     7141 caattgtcga atatatctcc tattaaatgg gttaatgata gtttgttcta tcttattttt
     7201 ggtggtcaat ataatccgat tcctgtaact ttgatcgtta atattagtat cggaacaatt
     7261 tttataatat tgtcattgat aggtatgaga aagcaggtga cgacatgatt tgttttataa
     7321 aaactctatt tgttaagata aagcgcaaaa aaacaagtta tgtgacattc tttttaatgc
     7381 ctattttaac gacacttttg gctttatctt tgagtttttc aaataataat caggctaaaa
     7441 ttgggatatt agataaagat aatagtcaga tatctaaaca atttattgct caactaaagc
     7501 aaaacaaaaa gtacgacatt tttaccaaaa tcaaaaaaga gcatattgat cactaccttc
     7561 aggataaatc tctagaagcg gtattgacta ttgacaaagg gttctcagat aaagtgttgc
     7621 aaggaaaatc tcaaaaactc aatatacgtt cgattgctaa tagcgaaatt acagagtggg
     7681 taaaggcaca gaccaattat ctattggaaa attataatat tataggggat gtggctctag
     7741 gtaacgaaga tacttttaat agaattctcc aaaaaaacca acagttaaat tatgatgtta
     7801 agcaagtaac tttgacagac cgatcacgta gcaaagcagt atcttccaca acgacaggat
     7861 ttttgcttat tctaatgtta ggtagtacga gcgtgattta cagtggtatt ttggcagata
     7921 aatctagtca gttataccat cgattaatgt tatcgaactt atctcgtttt cgctatatgt
     7981 tgagttacgt ctgtgtagga tttgttgctt ttacgattca aattgtcatt atgctgagtt
     8041 tgttaaaagt atttaatatt agtttttttg ttccgacatc acttcttttg attatttttt
     8101 tcctttttag tttattagcg ataggctttg gcctgctgat tggagctatc acacaaaatt
     8161 cccaacaaag tagccagtta gctaatctta ttgtaatgcc gacttcaatg ttggctggct
     8221 gtttatggcc attgtctatt acgccttctt atatgcaagc aattggtaag ttattaccac
     8281 aaaattgggt tttatcagcc atagctattt ttcaaagtgg agagacctta tctcaggctt
     8341 ggccatactt gttagctcta atgggaacag cactagcttt gattagtttt tcaagtttat
     8401 tattaaaacc taccaaacta taattagtct tttgttaaaa atactttcct aattagctaa
     8461 ctaccaggta gcccttttat tggcttatat gcaataaaag ggttgctttt tgcttatatt
     8521 ttctctagtg cacttatctt ttgttaaaag cgattgcgat gttactgttg ttactgtgtt
     8581 ttttagagag catattatca aaagcgacct ctctagaaag ttcgtttttg ttgataaatg
     8641 agttgtcaaa gcattttaaa aaaacgtttt caataaacat aaaaactaat gttatta
//
LOCUS       DAUGUF010000047         8663 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUGUF010000047 DAUGUF010000000
VERSION     DAUGUF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8663
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.047"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            8..2020
                     /locus_tag="VIB71_001553"
     CDS             8..2020
                     /locus_tag="VIB71_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEQ8823279.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSAN
                     VVAVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     VTTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKAKLVGAINTDTEAFITYITNLQASGKTVNATIKGV
                     KNYVTSNLERSTKINSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSFGKKE
                     TTTNKNTISNSTLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     gene            complement(2102..2512)
                     /locus_tag="VIB71_001554"
     CDS             complement(2102..2512)
                     /locus_tag="VIB71_001554"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ8823280.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLNLTGLTAQICQHELDHLEGILI"
     gene            3226..3303
                     /locus_tag="VIB71_001555"
                     /pseudo
     CDS             3226..3303
                     /locus_tag="VIB71_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3401..5278)
                     /locus_tag="VIB71_001556"
     CDS             complement(3401..5278)
                     /locus_tag="VIB71_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ8823281.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMASETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGNYSDYLDEKAFEKETVEADLAKAIVTEEMPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(5275..6483)
                     /locus_tag="VIB71_001557"
     CDS             complement(5275..6483)
                     /locus_tag="VIB71_001557"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEQ8823282.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDH
                     IEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            complement(6608..7456)
                     /locus_tag="VIB71_001558"
     CDS             complement(6608..7456)
                     /locus_tag="VIB71_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ8823283.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            complement(7456..7836)
                     /locus_tag="VIB71_001559"
     CDS             complement(7456..7836)
                     /locus_tag="VIB71_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEQ8823284.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            complement(7990..8240)
                     /locus_tag="VIB71_001560"
                     /pseudo
     CDS             complement(7990..8240)
                     /locus_tag="VIB71_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2724 a         1782 c         1386 g         2771 t
ORIGIN      
        1 agattttatg aaaaaatatt ttattttaaa aagtagtgta ttgagtatcc tgactagttt
       61 tactctatta gttacagatg ttcaagcaga tcaagttgat gtgcaattcc ttggcgtcaa
      121 tgattttcac ggcgctcttg ataataccgg aacagcttac acaccaagtg gtaaaatacc
      181 aaatgctggg acggctgctc aattaggtgc ttatatggat gacgctgaga tagacttcaa
      241 gcaagcaaat caagacggaa caagtatacg tgttcaagct ggagatatgg tcggagccag
      301 tcctgctaac tctgcacttt tacaagatga gcctactgta aaagtcttta acaaaatgaa
      361 atttgaatat ggcactcttg gtaatcatga atttgacgaa ggactagatg aatttaaccg
      421 tatcatgaca ggtcaagcgc ctgatcctga atcaacaatt aatgatatca ccaaacaata
      481 tgagcacgaa gcttcgcatc aaaccatcgt cattgctaat gtcattgata aaaaaactaa
      541 tgatatcccc tatggttgga aaccttatgc tataaaagac atagccatta atgacaaaat
      601 cgttaagatt ggcttcattg gtgttgtgac tacagagatt ccaaatctcg ttttaaagca
      661 aaactatgaa cactatcaat ttttagatgt agctgaaacc attgccaaat atgctaaaga
      721 actgcaagaa caacatgttc atgctattgt ggttttagct catattcctg caacaagtaa
      781 agatggtgtt gttgatcatg aaatggctac ggttatggaa aaagtgaacc aaatctatcc
      841 cgaacatagc attgatatta tttttgcagg acataatcat caatacacta atggaactat
      901 cggtaaaaca cgtatcgttc aagccctctc tcaaggaaaa gcttatgcag atgtccgtgg
      961 tacgctagat actgatacca atgattttat taaaactcca tcagcaaatg ttgttgctgt
     1021 agcaccaggt atcaaaacag aaaattcaga tatcaaagct ataataaatc atgctaatga
     1081 tattgttaaa acagttactg aacgaaaaat cggaactgca actaattctt caactatttc
     1141 taaaacagaa aatattgata aagaatcccc tgtcggtaac ttagtaacaa cggctcagct
     1201 tactattgct aagaaaactt ttccaactgt tgactttgct atgaccaata atggtggtat
     1261 tcgaagtgac ctagttgtca aaaatgaccg gaccatcacc tggggagctg cacaggctgt
     1321 acaaccattt ggtaatatcc ttcaagtcat tcaaatgact ggtcaacaca tttacgatgt
     1381 cctaaatcag caatacgatg aaaaccagac ctattttctt caaatgtcag gtttaacata
     1441 cacttataca gataatgatc ctaagaactc tgataccccc ttcaagatag ttaaggttta
     1501 taaagacaat ggtgaagaaa ttaacttaac aactacttac accgttgttg tcaacgactt
     1561 tctttatggt ggcggtgatg gcttttcagc atttaaaaaa gctaaattag tcggagctat
     1621 taacacagat actgaagctt tcatcacata tatcacaaat ttacaagcat caggtaaaac
     1681 tgttaatgct actatcaaag gggttaaaaa ttatgtaact tcaaaccttg aaagatcaac
     1741 aaaaattaat agtgctggca aacacagtat cattagtaag gtttttagaa atcgtgatgg
     1801 caatatagtg tctagtgaag tcatttcaga ccttttgact tctactgaaa acactaataa
     1861 cagctttggc aaaaaagaga caacaacaaa caaaaatact atctctaatt ccactcttcc
     1921 aataacaggg gacaattata aaatgtctcc tattatgaca atccttgcct tgataagctt
     1981 aggtgggcta aacgctttca ttaaaaaaag aaaatcctag cgtttactag taattgatca
     2041 tccttatata atcaggcatt ttcgccaaaa aaacctaaag tgtcctactc taggtttttt
     2101 gttaaattaa aataccttct agatgatcta attcgtgctg gcatatttga gcagttaggc
     2161 ctgttaagtt taaacgcttt ggtcgccaat tatggtccaa atactcaaca gtaatcttat
     2221 cataccgctg tgttttgcga tagccagata atgacaaaca agattcttta gtttggtaaa
     2281 ttcccttttt agaaaccatc acaggattaa acatcaccaa atcaataaat cccatactca
     2341 caataacaat gcgcttttgt tcaccaatca tattggcagc catcccaaga cattcctgtc
     2401 tataaaaggc taaggtatct tgtaaatctt ggccaatcca tagatcttct ttcttggcga
     2461 cttgcgcttt ttgctgtaat aaaaaatgat ctgttatgat ttctctaatc attcttatct
     2521 ccttaaacct tctttttaat tcataaacta catgttcaat ggactattat caccatatga
     2581 tagacttagt atcatctgtt taaaacatca ggtgattcct tatttcaaga tatcttgggc
     2641 aactttatga aattctgcaa tatgagtacc aaataaaaat tgacctgcat cagcagattg
     2701 ttgctaagtt ctcatcacaa tattatcgaa tttactgtct gcttcttcaa atgtctaaga
     2761 gagatagtta ttgctttgtg agattttcaa accagatact gctttctctt gcatttacag
     2821 ccttgatagg tccaaacaaa acacctgctg tttgaaatgc tttaatagct gatatgttgt
     2881 taatagttag tattataaat tttctgaata tttctgtcaa gtttttcagt tgacttaact
     2941 tttttacttg atttttcctc acgtaataat agaaaagaag cgccataatg taaactacac
     3001 cccaaacgtt agataaaaaa tctaacgttt ggggtgtttt tgtatgacat taagctatga
     3061 agataagcta gacatttagc gcttaaaaac tgagggaact ccgtttgaaa gaagcatctc
     3121 tgcaaagaag aagacaaaaa ccattataaa gaatggacaa agacgagttc tgattagatt
     3181 ttcttttaag aacggctaaa ttgactcgtt ctacctacta ttatcatcga ttattgcaac
     3241 aataaacgta tcaaaataaa acgaaaagaa cttagtcctc tacaatacag aactaaatcc
     3301 tttacttcaa atagagtagc caacttttgg ggctcagtgc aagagcactt cttttctatt
     3361 atcacttgtt tattataaac ataacattac catagtatac ttatatgtct agtccactca
     3421 aatactcaaa ccgttcatac gccaataata aatcattatt gcgctgatcg agttcctttt
     3481 gtaattgagc taactggcca taatcactaa ctacagttaa catttggttt tcaatttctt
     3541 caatattagc ctcaatagtt gctattttat cttctatctg agcccattct tgtttttcaa
     3601 ggtaggacat gcgctttttc tcctctttcg gaggaagtgg catttcttca gtgactattg
     3661 ctttagctaa gtcagcctca actgtttctt tttcaaaagc tttttcatca aggtaatcac
     3721 tgtaattccc ataaaaaata cgaatatcgc cttcttcaaa ggctaaaatc ttagtggcta
     3781 ctttgtctag gaaataacga tcgtgactaa ccgtaatgac tggtcctgca aagttagcta
     3841 aaaagttttc taagaccgtc aaggtggcaa tgtctaaatc atttgttggc tcatcaagga
     3901 gaagaacatt tggcttttca atgagcagtt ttagcaagta gagccgtttt ttctccccac
     3961 cagataattt agcaatcagc gtgccatgac ttgatctcgg aaaaagaaat tgctctaaaa
     4021 gctcactgat actcgttgtt cccacgcttg ttttaacctc atcagccact tcttgaaggt
     4081 aattaatgac ccgtttggtc tcatccatat ctttgagctg ctgagagaaa taacctacac
     4141 gaatagtatc tccaatatca agcttcccag aagttggttt gagatcaccg ttgatgatat
     4201 ttaacagggt agattttccg acgccgttat ctccaacaat tccaatacga tctttatttt
     4261 gaataatcaa gttaaaatcc ttaatcaact gtcggtcgcc ataagcaaaa gaaaggtctt
     4321 caaagtgaat caccttcttc ccaattcggc tcgtttcgga agccatctcc aatttatctg
     4381 cagaactgtc ttggtgaact tcttttttca agtcagtgaa acgattgatt ctagcctgct
     4441 gtttggttgc acgcgcctgt ggctgcgtcc tcatccaagc taattcttgt ttatagagtt
     4501 gcttcttctt gtgtaaatta gtagcatctc gttcgtcttg ttctgctttt aagcgcacat
     4561 agtcttggta attgccttga tattctgtca gtcccgcttt atccaattca aaaatacggg
     4621 tagccacatg atcaaggaaa taacggtcat gggtaataaa aaggacggtt tttttagctg
     4681 tcttgagata ggttgttaac caagcgatgg tgtcaatatc gagatggttg gtcggctcat
     4741 ccaacaagag taagtcagca gctcctagca atacttgagc taactggaca cgtcttctca
     4801 taccacctga taggtctccc actttttgtt ccaaatccgt gatgcctaat tttgatagga
     4861 ctgttttgac atcactttca atagaccaag catctaagcg atccatttca gacatgaggg
     4921 actctaaggt ctcttgttta tcttcagtat aattcgccat caatagttca tactgacgaa
     4981 tcagctgaat cgccttaaca tcagatgaca ataccgtatc taaaacagag gatgcatcgt
     5041 taaattcagg atcttgtgtt aagtaagcga ttttgtaatc attggcttta gaaaatggtg
     5101 aatggtctcc gtcaaaacca agccttcccg acaagacatc taaaagagtt gtttttcctg
     5161 ttccattaac cccaataatc ccaatacggt caaagtcatg aataataaag gaaatatcct
     5221 gaaagactgt tttatctccc accgtttttg tcaatttctc caccaaaaaa tggctcatgt
     5281 tgctaattcc tctctaacaa atgcttcaat tgtagtgaaa tcattatcta ggcgtccctc
     5341 tacaatcgct aattcaactt tctcaagcat aagccctagc tgaggacctg gtttcatccc
     5401 aaaatcctta atcaggtgag aaccattaag gacgatatcg tatttgttat gaatggctag
     5461 cgcttgatct aaagcttcaa tgtggtccat gtcaacagat aagctttgag cttttcggag
     5521 gccttccact agacttgcca tttccttgcc gtactggtaa atatccaatt tttcaaaaga
     5581 tctttcctga cgaattctat aaagagcaat caactttgtg acataacgct gaaaatcatt
     5641 tgaagtcttc catgctttta ggaagctttt aggatcctca atggctaaac taatcatcac
     5701 ataagcccaa gcttggtggt gatcactaaa ggtaaagtta tctttcaaag aaactatcag
     5761 atgattcaag cctgcttcct gctgcttcaa gcctggtaaa tagtcataag cctgacaagc
     5821 aatcatggca gaaatccctt ttcgccagtg cggtgccatc aataatttat caaattcagt
     5881 aaaagaacgt tccacagaaa tcttttccaa tagaggtgaa tggctcctca tagcttcaaa
     5941 agttgcagct tcaatgtcaa aatccagact cgccgcaaat cgaaagcctc tcataatgcg
     6001 tagtgcatct tcttcaaaac gttcctctgc tttacccact gctcgtaacc gtttttgctc
     6061 caaatcaatg agtcctctaa atttatcaat aacttgacca ttttcatcca aggccaaggc
     6121 attgacggta aagtctcttc gttttaagtc ttcctctaaa gagcgcacaa aagaaacctg
     6181 actaggacgg cgatagtcaa catagacatc ttctgtccta aaggttgtga tttcatactc
     6241 accgccattt tcaagcacga gcactgtacc atgttcaatg ccaacatcga cagttctgtt
     6301 aaaaatcgct ttagtctctt caggatagga actagttgca atatctacat catgaatggg
     6361 acgctcgagt aaaacatctc tgacgcttcc tcccacaaag taggcttcat aaccagcttc
     6421 ttttatttta gtcaatatgg gtaaagcctt ctgaaactca gaaggcattg tcattaattt
     6481 catacgttgt tttctaacct atcatccaac tagcccaatc taaagtgtga ttaggctact
     6541 tgggttctat cacattttgt tattgtttta gtgattcttg caattaacta ttttttctaa
     6601 tcgacaatta aagcctcggt gttacgccaa atgcaatggc tccttctcct aaatgagtag
     6661 caatcaccgc tccaaaatga acctcttcaa tgtcatattg ataaccactg tcttgtaaga
     6721 gtcgtttcaa ataatcagct ttgtcttgtg cttttgagtg aataatagac acattatact
     6781 gaccgtctgc tatcaagtca tttaaaatct caaccaagcg tttcatagct ttcttttctg
     6841 ttctcacttt ttcataaaca acgatttttc cctcttcatc aaagcgtaaa ataggtttaa
     6901 tactcaaaag atttccaaga agagcagacc catttgacag gcgtccgcct ttaaccagat
     6961 gattaaggtc atcaaccata ataaaggctg tcgtcccatc aatctgttct tgcagcttgt
     7021 ttaaaatagc ttgaaatgtc attccttgac gtgaccaatc tagcacattt tttaccatac
     7081 tacctaaagg agcagatgtg atcttactgt ctggaaatgc catttcaatc tcaggatgtt
     7141 cttcagctaa aaattgaata ttttgccaaa agcctgagat tcctccagct aagaacaagc
     7201 caataacatg tgtataaccc ttagaagaca aaagtcctaa aagattatct agttcagata
     7261 aacttggctg acttgtcttg ggaagatttt gggagtcagc catcttttga taaaaatcat
     7321 ctatactcaa atttcgacct tcaaaatagg tctcatcgtc aatgataact ggtatatcaa
     7381 ggctaaaaat agctttatct tgtttcagat ctgttggtag tgttgctgta ctgtcagtaa
     7441 ttactgctaa tttcattaat ttttaaactc caaatgaata cctggacgat ccaaggcaat
     7501 ttctgtgact tcataagtca atcgcttaac catgtctagc aaaggagcag ctaaggattc
     7561 aacttcctct tgcgtaaatt cgcttggttt atccactaaa cgatctaaaa tacgaaccat
     7621 ttgtgagatg accccactaa taacaaattc ttctttgaca ataacaaatt gcaatacaga
     7681 tacaattact gtttcttttt gctgctcatc tttatcaatc aactgaaaag tcacttcaaa
     7741 attggtctct ggtgttccgt tttctttttc ccactctaaa tttctagcat cataatggta
     7801 ctggttgaca aattcttttt cacgaactaa ttgcattttt tattctcctt ggtatcaata
     7861 tgatccatta tagcatagat ttgaaaatta ttaaagtagc ccctaaacta ctattttcgc
     7921 ataacgtttt aaacagtgct atctctcgaa cagatatcta ttttttcacc tatttatatt
     7981 tagtcgtcct tatactgaca ttatatcaaa aaaacacccg ttagtggtct tgtactgcac
     8041 ctcaattaaa acagaaccac tggtcaggta agttttaagt ccaggataaa aaggtttatc
     8101 accaaggcct catcatgctt agccaagtat ttcgaactag cttgtcttag ctctagtcgc
     8161 tcaaacgtaa atcctaggcg ttcaatccgc cgcaaaactt ctccaactaa cccatactta
     8221 aacccatagg gcttaatcat cgctccgccc ttcttctttt atccattata aaataaaaac
     8281 gttttaacag acaaaaaata ggaaagtacc agactattgg atttattttt ttatctcaaa
     8341 ctccattaac gatgttgagt taaaggcatt caaaacaaca tagatcgtaa gctaacaaga
     8401 ttttttatca attgaaccta tcgtccccag ttatatcacg acctcttctg gatgaggtct
     8461 ttttttattt gtctaatttc atcaacgctt cttcccctct ttcttctatc acagctctcc
     8521 tattgctcac ttcctcatgc agcaacatat catcaaaaaa ccgtccattt ttaagcacaa
     8581 ccactactgt atctcttgtg atatctccat tgtcaatcgc ttgtttaatt ttattaaaaa
     8641 ttattttaaa aaataaatat tat
//
LOCUS       DAUGUF010000048         8318 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUGUF010000048 DAUGUF010000000
VERSION     DAUGUF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8318
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.048"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            161..859
                     /locus_tag="VIB71_001561"
     CDS             161..859
                     /locus_tag="VIB71_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8823285.1"
                     /translation="MFSGHQLKTVRLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            complement(994..2556)
                     /gene="ffh"
                     /locus_tag="VIB71_001562"
     CDS             complement(994..2556)
                     /gene="ffh"
                     /locus_tag="VIB71_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEQ8823286.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPDEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KTMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(2571..2912)
                     /locus_tag="VIB71_001563"
     CDS             complement(2571..2912)
                     /locus_tag="VIB71_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEQ8823287.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            complement(3001..3699)
                     /locus_tag="VIB71_001564"
     CDS             complement(3001..3699)
                     /locus_tag="VIB71_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ8823288.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            complement(3782..5215)
                     /locus_tag="VIB71_001565"
     CDS             complement(3782..5215)
                     /locus_tag="VIB71_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823289.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKEPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            5382..6944
                     /gene="guaA"
                     /locus_tag="VIB71_001566"
     CDS             5382..6944
                     /gene="guaA"
                     /locus_tag="VIB71_001566"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEQ8823290.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILQNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            complement(6986..8209)
                     /locus_tag="VIB71_001567"
     CDS             complement(6986..8209)
                     /locus_tag="VIB71_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ8823291.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPNVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
BASE COUNT         2486 a         1583 c         1483 g         2766 t
ORIGIN      
        1 gacctgctag tacacgaatc tagtcgctat gttttaggtg tttccccttt ttgacagtat
       61 tgctatcaca tgaattaatt gtaggaaatg ttacacttgc tttcgtttta tttttttgat
      121 actattagta aagttataac tttactaaag gagctaccaa atgttttctg gacatcaact
      181 aaaaacagta cgattatcaa agggaataac tcaatcagaa ttgggaagat tgttgcatgt
      241 caataaaatg acaatatcta attgggaaaa aggtaagaat ataccaaatg aaaaacattt
      301 aaatgcctta ttgcatctat tcaatgtgac atctgattat ttcgacccaa actatagatt
      361 gctaacgcct tataaccagc tgacaatatc taataaagaa aaagtaattg gctattcaga
      421 gcgattgtta aatcatcaaa tagacaaaaa atctaaagat ctcatagata aaccatcaca
      481 attatatgct tatcgggtct atgaaagttt atctgctggt actggttact cctattttgg
      541 tgatggtaac tttgatgttg tcttttacga tgaacaatta gaatacgatt ttgcgtcttg
      601 ggtttttgga gattctatgg agccaactta tttaaatggc gaagttgttc ttataaaaca
      661 aaatagtttt gattacgatg gagcaattta tgcagtcgaa tgggatgggc aaacatatat
      721 caaaaaggta tttcgtgaag atgagggatt acgtctagtg tccttaaata aaaaatattc
      781 tgataagttt gctccctata gcgaagaacc tcgcattatt ggcaaaatta tcgctaattt
      841 taggccctta gaaatttaag ttagattgat taggttattt caaattttaa atgaactcat
      901 catgcatgta acgcggtctt ccataatttt aataatcttg tatacaagat aaatgaattt
      961 cacatcaaaa agagacgaaa atttccgtct cttttatttt cgttttttct ttgctttttt
     1021 tagtttgtta gcttgacgtt tcatggcctg tttcatggca aattgtccaa ttttcccctt
     1081 gaacccttta ccaaatagtt gactcatatc catatcacca ccaaggccag ataaatcggg
     1141 cataccacct tgtcccatca tcccttctaa ggaagacata tctggcatac cagcaggcat
     1201 ggttttagga agattattgg gattaatgcc catatctttc atcatcttag acatatcgcc
     1261 cgacataacc ccttgcatca tgcttttggc ttggttaaag tctttgataa atttattaac
     1321 ttccacaaag ctgttcccgg aaccagcagc aatacgacgg cgacgactcg ggtttagtaa
     1381 gtcagggttt tcacgttcag cgggggtcat cgaagagaca atagcacgtt tgcgagcaat
     1441 ttggttttcg tcaactttga tattggccaa agctgggtta ccagccattc ctggaatcat
     1501 tttcaagagg tcttccatag gccccatatt ttgcacttga tctaactgtt caatgaaatc
     1561 attgaaatca aaggtgttct cacgcatttt ttcagctaac tctaaggatt ttttctcatc
     1621 atattcctgg ctagcttttt caataagagt gagtaagtca cccattccca aaatccgact
     1681 ggacatgcgg tctgggtgaa atgtttcaat atctgtgatt ttttcaccaa tacctgtaaa
     1741 tttaattggt tttccagtga tttcacggac agatagtgct gcacctccac gggtatcacc
     1801 atcaatcttt gttaacacaa cccctgtgat gctcaactga tgattaaact cgtaggctac
     1861 attggcagct tcttgaccaa tcatgctatc tacaaccaaa agaatttcat ctggttgtgc
     1921 taaagccttg acatcgcgca gctcttccat cagtttttca tcaatttgca agcgacccgc
     1981 agtatcaatc aagacatagt cattgcggtt ttcacgagct tgttccaaac cttttctgac
     2041 aatatcgact gctgagtggt ctgtccccat atcaaaaaca ggtacattga tttgttgccc
     2101 cagtgttttt aactgatcaa tggccgctgg acggtaaata tcggcagcaa tcatcagtgg
     2161 tcgcgcgttt tcttctttaa ttaatttatt agcgagtttt cctgcaaaag tggttttacc
     2221 agccccttgc aaaccgacca tcatgataat agttggaatt tttggagatt tatcaatctc
     2281 cgcggtttct gagcctaaaa tactcgttaa ttcttcatta acaatcttaa gaatttgttg
     2341 tgttggatca agagtatcaa taatctcatg gccaatagcg cgctcacgta cgcgcttaat
     2401 aaaggtttta acaactggta aagcgacatc ggcttctaaa agagctagac gaatctcttt
     2461 tgtcacttct tgaacatctg attctgataa tttcttttta ccgcgaatgt gtttaaacac
     2521 atcttgcaaa cgttgggtta agctttcaaa agccatagtc aaaactcctc ttactctcta
     2581 ttgtcaatac tggttagaat ggaaattttt tcttgcaaat actcatcatg agggtagtga
     2641 gcaatcatgt cgtcaaagat ttcacttcga acaacataat ccgaatacat atgaagtttc
     2701 atctcataag tctctaaaat tttttccgta cgcttaatat tatcatagac agcctgacga
     2761 ctgacaccaa attcatcagc aatctcagct aagctataat catcggcata atacagctca
     2821 atataattca tttgtttatc tgttagcaaa gctgcataaa attcaaaaag ggcattcatc
     2881 ctgtttgttt tttcaatttc cataatgttc attttatcat actatgattg tttttaacag
     2941 tagcaaatta attgccttat gctgttcgtg taaaaaagga agtcataaat gacttcttta
     3001 ctaattattt tctaagtaaa attcaaaacg gtcaccgata tactgactgc ggacatactc
     3061 aaaaggtttg ccgtctgtaa agtaagacac ctgagttaga gccaaaatgg catgtccttt
     3121 agcaacttcc aagtaggagg ctacacgctc acttgctagc ttagcgtaga ttgtctgttt
     3181 acttttacca atctcgtaac catttgctat caatgagtga aaaaagtgtt ctgtaatatc
     3241 agctcgttta accgttttta taaatttttc tgggattgaa gcaatttcgt acaccaaagg
     3301 gacactgtct gcatagcgga tacgttccat tcgaatgacc aagtctgttt tgtctaagtt
     3361 caattcttta acttcggtat cactagctaa ttgcttttga taggataata atttagagga
     3421 gggttgtcgt ccttgggagc gtataatttc tgtgaaactt gttgttcctc gcattttttc
     3481 ttgaacacga tgactggcaa cataagtacc acttcctatc cgcctttcaa gaatcccttc
     3541 ttctactagt aatgtaatag cctgccgtag agtcattcga ctaacggtga aatgttccgc
     3601 taaatgtcgt tcacttggta agcgactacc aattggccag atgcccagat caatgtcttt
     3661 tttaattgca tcatgaattt ttatataagc tggtaacatg ccacactcct caagtcggtt
     3721 attcatctat tttatcatat ttttgatgaa aattgaattg taaatattga ggtatttggc
     3781 atcaattaat gatattacct gcgacaataa ctggtgaatt tggtggaaaa tgaataggtt
     3841 ccataaacca actagtgagc ttcgctttag taacaatgga tgaggtaaaa acattattta
     3901 aaaccctaat aactcctact tttgaggaat gctgaccaat agaaccacta taggctctca
     3961 ggcaaccagt cggatctata taaggtaaaa attgattttg gcttacagta atattgtgac
     4021 atagatgtcg agtttggtta aatgcttcat agtttggagc aatattacta agtagacctc
     4081 catcccatgc aaaatgatga acagcagcat caaactgaat gacttctgaa aaaaaatcat
     4141 gcccttgagc ctttgatagc agctgttggt cttgtactaa ttctggcgca tagccaataa
     4201 attggttttt ctcaaacaat gaattttgta gagatcctaa atcaaaaata tgactattac
     4261 gcttatgaac catagtaaat ttgttatcgt aaatatgcca atcagtacca tgatcagcca
     4321 taatcataaa gtggtctcct tttttcaaat catttgcttt gaaatgcact ccagtcaaca
     4381 cgagattacg aacaccttgt tcagcctttg gtcctgtagg gaatccaaac cacaacattt
     4441 taccgtgaat aatgaactct gtctgatgac caataatagc tgtatcagat ggaagctcaa
     4501 aataatcttt ttgtgaaggc aaagagccaa tgtgaaattg tccctttgga aaagatataa
     4561 cgctatttgg atgctgcttt gcataagcga aagcttttcg caaaagacga ttgttttgct
     4621 caggggaatt tcctttattg aacctaatat aataaggttt aacaaaatct tgctctgaaa
     4681 ttccatctaa tcttagatta tctttcagat taatatcgta ctgatatcct cctaacgaat
     4741 agtcatagcg ttttttaact tgtttaatag tcgctaattg accttgatat acttttatat
     4801 gtggcttttt agttaatgaa gataatttaa cgatatctcc ttttttaaac ctcggtttat
     4861 caggctcttt caggttatgt tctggcaaag aaacagtgac ttttcctatt ggaaatacca
     4921 cttcataatg ataactcact cggtaatttt cggctatatc ttctacctgt ttattaatag
     4981 ttccaatcca ttgatgatat ggaccacttt tttgtacttg aatagcttgt ccaatgtgat
     5041 agcgaggctg ttgatctttg cttcgttcca ctattccgac agttgctaat atattgtgaa
     5101 gtgttgcaaa actattggtc cacgcaaggt acgaaacaac taaactcaac aataatccta
     5161 ggaaaattaa ttcaacaggt cgaaataaac ccaaaattct cttttttctt agcataggcc
     5221 ctccctgttg tcttaattcc ctttcatagc ctctattgta acataacgat tacgtttttt
     5281 tccaacgagc tagagaaatt gtaatgtctt ttcgatgaaa atatgctaca ataagttgac
     5341 aactatcagc ctgacggttg gtatagaatg aaaggattat aatgactgaa atttcaattt
     5401 tgaatgatgt tcaaaaaatt atcgttcttg attatggtag ccagtacaat cagcttattg
     5461 ctagacgtat tcgagagttt ggtgttttct ccgaactaaa aagccataaa atcaccgctc
     5521 aagaacttcg tgagatcaat cccataggta tcgttttatc aggagggcct aactctgttt
     5581 acgctgataa cgcctttggc attgaccctg aaatctttga actagggatt ccgattcttg
     5641 gtatctgtta cggtatgcaa ttaatcaccc ataaattagg tggtaaagtt gttcctgctg
     5701 gacaagctgg taatcgtgaa tacggtcagt caacccttca tcttcgtgaa acgtcaaaat
     5761 tattttcagg cacacctcaa gaacaactcg ttttaatgag ccatggtgat gctgttactg
     5821 aaattccaga aggtttccac cttgttggag actcaaatga ctgtccctat gcagctattg
     5881 aaaatactga gaaaaacctt tacggtattc agttccaccc agaagtaaga cactctgttt
     5941 atggaaatga cattcttcaa aactttgcta tatcaatttg tggcgcgcgt ggtgattggt
     6001 caatggataa ttttattgac atggaaattg ctaaaattcg tgaaactgta ggcgatcgta
     6061 aagttcttct aggtctttct ggtggagttg attcttcagt tgttggtgtt ctacttcaaa
     6121 aagctatcgg tgaccaatta acttgtattt tcgttgatca cggtcttctt cgtaaagacg
     6181 agggcgatca agttatggga atgcttgggg gcaaatttgg cctaaatatt atccgtgtgg
     6241 atgcttcaaa acgtttctta gaccttcttg cagacgttga agatcctgag aaaaaacgta
     6301 aaattattgg taatgaattt gtctatgttt ttgatgatga agccagcaaa ttaaaaggtg
     6361 ttgacttcct tgcccaagga acactttata ctgatatcat tgagtcagga acagaaactg
     6421 ctcaaaccat caaatcacat cacaatgtgg gtggtctccc cgaagacatg cagtttgaat
     6481 tgattgagcc cttaaacact cttttcaaag atgaagttcg agcgcttgga atcgctcttg
     6541 gaatgcctga agaaattgtt tggcgccaac catttccagg tcctggactt gctatccgtg
     6601 tcatgggagc aattactgaa gaaaaacttg aaaccgttcg cgaatcagac gctatccttc
     6661 gtgaagaaat tgctaaggct ggacttgatc gtgacgtgtg gcaatacttt acagttaaca
     6721 caggtgtccg ttctgtaggc gtcatgggag atggtcgtac ttatgattat accatcgcca
     6781 ttcgtgctat tacgtctatt gatggtatga cagctgactt tgctcaactt ccttgggatg
     6841 tcttgaaaaa aatctcaaca cgtatcgtaa atgaagttga ccacgttaac cgtatcgtct
     6901 acgacatcac aagtaaacca cccgcaacag ttgaatggga ataacagaat aaacattaaa
     6961 agactcgctc attttggcga gtcttttaat gtttattctt taactgtttt cgtattttgt
     7021 acatggtatt agcaatatga taaagtgggc tgacagggag attaaattct cctataaatt
     7081 cttctattgt cggagcaaag ttggccttaa atttggtaag tccatcatca agcgagcctt
     7141 ctactcctcc catgttagcc caaataatac catcttgata agcatcctga aaaacattag
     7201 gatacagcag atactgagga taaaacttct taaaatcatc attcatccca gcataaagca
     7261 tttccataac atttccataa gaaatagata atatacctgc tacaacaact tcctcaggat
     7321 attggtctgt aaagccttca aattcagtta tataacgttc taaagaagct ttttgatctt
     7381 ctaatttttt taaacgcttc ttttgatgag cttgggtgcg agtaatatct tggttaataa
     7441 gaattaattg ctggcggtat tgatctagtt tttgaggaat attcactttt gctagatgta
     7501 agtaggcctt atccccataa gtagtcatca acttttgaaa gtaagcttcg ttacgcaaag
     7561 aaatattttt acgtttttct gttaaggaga caatcttgga aaatttgtga agttctgatt
     7621 gactggcacg atatgtttct acaccacgct gcttagcatc ttttattaaa cgtctggtat
     7681 gcttaggaaa ttgcatctca aggttttctt gagtgtaaat attagcttgg aaacgaggtt
     7741 ggatactatc tgcaatctcc attgttaaac cagtccaatg aacaccagct tcttggagat
     7801 tcttaatagc tgctaaagct aaaggttttt cttcttcttc ctgtcccagt gcgtattgtt
     7861 ttaacaggat agctggatca tatttgataa agagggcctt tttagtttta ccataatcct
     7921 ttagtgtttt catggtaaat gccaccaaat cacggtcaag ataatccatg actggccctc
     7981 ttggaatata aataatgctt cttccaagtg gcaatagctt aatcaaaagt gataaagagg
     8041 caacctgctt ttcctcttta tagataccaa ttcgctcatt ctgccattga tttttgattt
     8101 ttgcccaatc actaccttgt aaaacgctaa tttgctgatg ttctttaaca aaagagtcat
     8161 gctcttcttc tgaaataccg atttttgcat aaaacgttaa attcgtcatt tattgtcccc
     8221 atctattcgt aatcttagca gatgtactta ctaatcatct tcactgtctt tatctattta
     8281 ttcgtaataa atgttaaaaa aacataaaaa tagggaaa
//
LOCUS       DAUGUF010000049         7597 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUGUF010000049 DAUGUF010000000
VERSION     DAUGUF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.049"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..404
                     /locus_tag="VIB71_001568"
     CDS             <1..404
                     /locus_tag="VIB71_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ8823292.1"
                     /translation="NMNNIFQFGALSYGITNLFPLYVCFFFFVYISNASKITINIVEK
                     MGIIFVISAIIGATVLAMYLTWTPVGSSTVLGVQSRYLIGIIPLVLLLFSSQQQKFKQ
                     IEDILSDKLAIHVSLLFILAMLMSTIFRYYH"
     gene            498..1721
                     /gene="pepT"
                     /locus_tag="VIB71_001569"
     CDS             498..1721
                     /gene="pepT"
                     /locus_tag="VIB71_001569"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEQ8823293.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAHLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            1762..2250
                     /locus_tag="VIB71_001570"
     CDS             1762..2250
                     /locus_tag="VIB71_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEQ8823294.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(2237..2434)
                     /locus_tag="VIB71_001571"
     CDS             complement(2237..2434)
                     /locus_tag="VIB71_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEQ8823295.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            2483..2959
                     /locus_tag="VIB71_001572"
     CDS             2483..2959
                     /locus_tag="VIB71_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ8823296.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            2974..3654
                     /locus_tag="VIB71_001573"
     CDS             2974..3654
                     /locus_tag="VIB71_001573"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEQ8823297.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWI
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    3678..3801
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            3816..4346
                     /gene="infC"
                     /locus_tag="VIB71_001574"
     CDS             3816..4346
                     /gene="infC"
                     /locus_tag="VIB71_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEQ8823298.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            4388..4585
                     /gene="rpmI"
                     /locus_tag="VIB71_001575"
     CDS             4388..4585
                     /gene="rpmI"
                     /locus_tag="VIB71_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEQ8823299.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            4644..5003
                     /gene="rplT"
                     /locus_tag="VIB71_001576"
     CDS             4644..5003
                     /gene="rplT"
                     /locus_tag="VIB71_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEQ8823300.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(5294..7504)
                     /locus_tag="VIB71_001577"
     CDS             complement(5294..7504)
                     /locus_tag="VIB71_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEQ8823301.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGGALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAILASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILTQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYNGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTKNRE"
BASE COUNT         2475 a         1235 c         1499 g         2388 t
ORIGIN      
        1 ttaatatgaa taatattttt cagtttggcg cattaagcta tggtataacg aaccttttcc
       61 cgctttatgt gtgtttcttc ttttttgttt atattagtaa tgctagtaaa ataactatta
      121 atattgtaga aaaaatgggt ataatctttg ttatttcagc gattataggt gcaactgtat
      181 tagctatgta cctgacttgg acaccagtag ggtcctcaac tgtcttaggt gttcaaagtc
      241 gttatctgat aggaattatc ccattagtgt tgcttctttt tagtagtcaa cagcaaaagt
      301 tcaaacaaat agaggatatc ctttctgaca aactggctat tcatgtttcg cttttgttta
      361 ttctcgcaat gttaatgagt actattttta gatattatca ttaaactctt aattagaggc
      421 tttaaaaaac ttagcttgaa taagtatttt aaagcctttt atgctataat taaattgaga
      481 aattattgag gtggcctatg aagtacgata acttgttaga tcgatttata aaatatgtca
      541 aagtgaacac aagaagcgat ccagacagtg agactactcc tagtacggag agtcaagaag
      601 catttgcctt aacgatttta aagcctgaaa tggaggcaat tggtttgcaa gatgttcatt
      661 ataatccagt taatggctat cttattggaa ctctgcctgc caataatcca accttgacgc
      721 gtaaaattgg ttttatagcc catatggata cggctgattt caatgctgaa aatgttaatc
      781 cgcagattat tgacaattat caaggagggg acattacact tggcagttct aattataagt
      841 tggatccaaa agcatttcca aatcttaata attatatcgg tcaaacattg attaccactg
      901 atgggactac acttttaggg gcagatgata aatctggtat tgctgaaatc atgacagcaa
      961 tagaattctt aacatcacaa ccacaaatag agcactgtga cattaaagtg gcttttggcc
     1021 ctgatgaaga gattggggtc ggagctgata agtttgaggt ggctgatttt gaggtggatt
     1081 ttgcttatac tatggatggc ggtcctttag gcgaattgca atatgaaact ttcagcgctg
     1141 cagctctaga agtgactttt ttaggcagaa atgttcatcc tggtacggct aaggatcaaa
     1201 tgattaatgc ccttgagtta gcaatagatt ttcatgagaa gctacctgct aaagagcgac
     1261 ctgaatacac agatggttat caaggcttct atcacttaac gggactaact ggaacagttg
     1321 aagaggcacg cgcatcttac attattcgtg attttgaaga agcatcattt gaagctagaa
     1381 aagtgaaagt tgaaaatata gctcaatcga tgaatgctca tctaggaaca aaacgtgtct
     1441 tggtagagct taatgaccaa tactacaata tgaaaaaagt tatcgaaaaa gatatgaccg
     1501 ctattgagtt agctaaagaa gtaatggaag agcttgctat caagcctgta atcgaaccca
     1561 tacgtggagg aacagatggc tctaaaattt catttatggg tattcccact cctaatattt
     1621 ttgcaggggg tgagaatatg cacgggcgtt ttgagtttgt tagcttacaa acgatggaga
     1681 gagctgtcga tgtcattatt ggacttgttt gcaaagccta attatcatgt aattgatatt
     1741 tagtggaagg ggcttataaa aatgattaaa ctatttggta aaataaggta tcactggcag
     1801 ccagagttgt cttggtctat tatttattgg tctattgcgt ttgcacctat ttttgtaggt
     1861 ttatctttgt tgtatgagcg cactgaaata cctagtcggg tttttattct atttgctatt
     1921 tttgctgtcc tagttggcat tggattacat cgttatttca ttattgaaaa taatggtatt
     1981 ttaagaatcg tatcttttaa attgtttggt ccacgtaagc tacttatttc tactattact
     2041 aagattgagg tgaccaaatc aacactttgt ctgcacgttg aagataaaag ttatctcttt
     2101 tatatgcgca aatggcctaa aaaatatttt cttgatgcct tagcggttaa tccatacttc
     2161 caaggagaag ttatattaag tgataacttt attaaattag actattttga agtttatcag
     2221 catgataaaa aagcccttac tcgagggtaa gagctttagt tgggcaagat ttgacagcta
     2281 aaatagcgtc cttatctgaa ggacaaattg actgacttgt ttcagatgag cttgaaaatg
     2341 tgacgatacc attgtcatga taatcaaaaa gtgatgaata ggtttggcat agaccacaag
     2401 cgatgcattt ttctggaatg atagatactt tcataactat tattctaata tgattttgtt
     2461 aaattaacaa ggggggacga tcatggctaa agaaccatgg gaagaaaaaa ttgttgatga
     2521 tactataggg acacgaacac gtaaatcaag aaatgctttc attagcacgc cttggttgac
     2581 tgctttatta agtgtattct ttgtcatcat tgttgctata ctttttattt tcttctatac
     2641 atcaaatagc ggtagtaata gacaagctga aacaaatggt ttttatggag catccactca
     2701 taaaaaaaca aggaaagctt ctaacgctaa aaaaacatca agtagttcaa caactacaga
     2761 cacaacacct tctagcgaag aaacacttgc ttctagtgaa ggaactggcg aaacccttac
     2821 tgtattggca ggtgaggggg cagcttctat tgcagctcgt gcaggtattt ctgtggagca
     2881 gctacaagca cttaatccag agcacatgac tcaaggatat tggtatgcca atccaggaga
     2941 tcaagtcact attaaataat tgaagaggaa aaaatgaaag caattaaaat tgcgattgat
     3001 gggccagctt caagtggaaa aagtacagta gccaagatta ttgcaaaaaa tcttggctat
     3061 acttatctag atactggtgc tatgtatcgc tcagcaactt atatcgcact gacacatggc
     3121 tatacgggta aagaagtagc ccttatttta gaggaacttg agaaaaatcc tattttcttt
     3181 aaaaaagcaa aagatggctc ccaattagtt tttcttggag atgaggacgt gaccttagcc
     3241 attaggcaaa atgatgtgac taacaatgtt tcttggatct cagctttgcc agaaattaga
     3301 gaagagctgg ttcatcaaca aagacgcatt gcacaagctg gtggcattat catggatggt
     3361 cgtgacattg gaacggttgt tctcccagat gcggaactaa aaatcttttt agtggcttct
     3421 gtcgaagagc gggcagagcg ccgctataaa gaaaacctag aaaaaggaat tgaatcagat
     3481 tttgagacgc taaaagaaga gattgcagct cgtgattaca aggatagcca tcgtaaggtt
     3541 tcacctctaa aagcagctga agatgccctt atttttgata ccacaggtgt ttctattgat
     3601 ggcgtggtgc aatttatcca agaaaaagca gaaaaaatag ttgacatgtc ctagagccta
     3661 tgttagaata ttaacaatga gaaaagtaga agtgagagct tctcgccttg cgacttaggt
     3721 tgtctggccc taacatgtcg aattcctatg gaatattatg tgtgcgggct tgatttatca
     3781 agtccgcttt cgtttttctc taaaaaaata aagaggtgaa gatcatagct aaaaaggatc
     3841 tattcattaa tgatgaaatt cgcgttcgcg aagttcgtct cgttggtctt gaaggtgaac
     3901 aattaggtat taaaccattg tctgaagcgc aatcattggc tgatgcttca aatgttgatt
     3961 tggttttaat ccagccacaa gctgttcctc ctgttgccaa acttatggac tatggaaagt
     4021 tcaaatttga gtatcaaaag aaacagaaag aacaacgtaa aaaacaaagc gttgtgactg
     4081 tgaaagaagt tcgtctcagt ccagttatcg ataaaggtga ctttgaaaca aaacttcgta
     4141 acggtcgtaa attccttgaa aaaggaaata aagttaaggt ttctattcgt ttcaaaggac
     4201 gtatgattac tcataaagag attggtgcca aggtactagc tgactttgct gaagcgactc
     4261 aagatattgc tatcattgag caacgagcaa aaatggatgg acgccaaatg tttatgcaac
     4321 ttgcaccaat ttcagacaag aagtaattgt cacagtttca ttatatcttt aagaggagaa
     4381 tactaaaatg ccaaaacaaa aaacacaccg cgcatcagct aaacgtttta aacgtacagg
     4441 ttcaggcggt ttgaaacgct tccgcgcctt tacatcacac cgtttccacg gaaaaactaa
     4501 aaaacaacgt cgtcatcttc gtaaagctgg tttggttagc tcaggagatt tcaaacgtat
     4561 caaagcaatg gttactggtc tttaatttta aaggcagtag acatttacga gtattataag
     4621 aattatttga aggagaacta ttaatggcac gtgttaaagg tggcgttgtt tcacgcaaac
     4681 gtcgtaaacg tattttaaaa ttagctaaag gttactatgg agcaaaacac atcttgttcc
     4741 gtactgcaaa agagcaagtg atgaactctt actactatgc ataccgtgac cgccgtcaga
     4801 aaaaacgtga tttccgtaaa ttatggatca ctcgtatcaa tgcggctgct cgtatgaacg
     4861 gtttgtcata ctcacaattg atgcacggtt tgaaacttgc tgaaatcgaa gtaaaccgta
     4921 aaatgcttgc tgatttagca gtagctgatg cagcagcttt cacagctctt gcagatgcag
     4981 ccaaagcaaa acttggcaaa taagaaacgc tatacctaga aaataacttt ttattaccta
     5041 tagaaagtta taaagaaaca aaaatgaagg agacgatgga cgtcttcttt ttattatact
     5101 caatataata aaaagaagtt tcccatgttt tattaccagt aatgtgggat atttagatgg
     5161 tagcaagaag ttttatagtt gatttgtttt ctttaggtct aattagcata ttttgattac
     5221 tgataaactt gaatatcgcc aataaaaaag aagcaaaatt attattttgc ttctagtcag
     5281 atcattaaat tgattattct ctatttttgg tgttatcctc ttttagttca gaagttgccg
     5341 cgtcagcttc tacgggattt agttctaagt aagatggtgc tttaaaaagt ttctgagttg
     5401 atttatgacc atttttactg tataaacttg ttgactctga tccgagtttt gctgaaatat
     5461 ctttcagttg ttttaactgc ttagtgtaga taaactggtt aggatcaata gcttttagac
     5521 cattttgagt atcaaagcgc aggagatcac ccgtttgaat agcgtcgcta gctgctagtt
     5581 gttgagcaac agcagagcga atttccttag ttttggctat agtcatttca tcgggattag
     5641 tgatttctaa acctgtttgc gtgttgtaca gacgtccatt atagttagtg tattcaggag
     5701 tcatataagt cccagatgtt cgttgtgcca caatctggct attttgaggt gataataaat
     5761 cttgtcctaa ttgaacaaac tgactagtgt caataccaag tatgtggagt aaagtaggaa
     5821 gagcatcgat ttcaccgcca aaggtttctt tgatactacc attcgtataa cctggaatat
     5881 ggatcatata cgggactcgt tgtagcatag cattatcata ttcagaccaa gtttcagaat
     5941 ctttaccaag aagtggagca agactagaat tacgagaatt tgaaatacca taatggtcac
     6001 catataaaac aaaaatagaa ttgtcgtaca aaccagtggc tttcaagtaa tcaaaaaaag
     6061 atttaagggc agcgtctaaa taattggcag tagcaaagta accattgatc gtttcatcgt
     6121 ctgttttggc taaaggaaaa ccttcttcac tactttcgcc ttttagacta gtataaggat
     6181 agtgattact cacagtgata aacttggtat aaaaaggttg ttgcatctgt tcaagatatt
     6241 ttatggaatc cttaaacatg tacttatcat ttaacccata ttgaaaagag ttcttactat
     6301 tttgtttaga gaagtagcta gaatcaaaaa aataattata gccccattgt ttataagcat
     6361 tattgcgatt ccagaaagtt ccaacgttac catgaaagac agcgctggta tagccacctt
     6421 tttgggttaa aatacttgga gtagcaaatt gtgtattttc accaccgtag ttcaccataa
     6481 aagaaccact atttaaacca aataaggaat tctccatcat ggtttcagca tcagaagttt
     6541 tacctgcttt aacctgatga aaaaagttag ggaatgctaa ggtagcattt gagtgataaa
     6601 gcgagttgat aaaaggcgtt acctcatatt ctttatctcc ttcttttagt ttataatcta
     6661 ttaagaattg ttgaaagctt tctaaatgaa gaacaataat atttttgcct tttccaattc
     6721 caaaatactg aggatcaggt gctgcataat gtcctttgac ataagtttta acatcaatta
     6781 attcttctgc agtagctcca tttcgttctt tttgagcttg ataggtttga ttgccgctat
     6841 agagggtaaa cgctggtagt cctaaagctc tcacaatata agtatttgaa aagccacgtg
     6901 ttaatagttc cggacgatca atttctgcta aaaaaagatt aatagaaagc aatagactag
     6961 ataaagcggt gatggcaaat gctgcgcgct tgttaaaagg acgttggtca tttttgattt
     7021 ttttagtgat agataaacta attagaataa taaaatcaag aatatagata atatcccaga
     7081 tgcgtaaaag gtttaaagca gagtccccta atccagcgga gactttacta ctagctagta
     7141 tggcactcac tgtaataaag tctgaaaatt ctcggtaata tatagaattt gatatcaaga
     7201 gaatgttaag gataatataa accacccaag aacagatata aaaggctcgg gtattcttaa
     7261 cgtaaagagc accccccaaa agtaaaaaag ctagtgggat tggattgata atagttagaa
     7321 agacttggta tatatttccc aaatctagtg aaaagtctgt atgatatgcc cacagggtct
     7381 ttatccagta acaaaagagt agagtaatta taaaacccaa tcttgtgttg ataaaacctg
     7441 tgataagtgt tttaaatttc ttcacagtag caacttcctt atcgtttttt cctaaagatg
     7501 tcatctccaa ataaaatctc agattaaatt ataccaaaaa tgtgaagcta atgcttgttg
     7561 taagttcaaa tttagtagga ttttttatca gattttg
//
LOCUS       DAUGUF010000050         7016 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUGUF010000050 DAUGUF010000000
VERSION     DAUGUF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7016
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.050"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(99..1358)
                     /locus_tag="VIB71_001578"
     CDS             complement(99..1358)
                     /locus_tag="VIB71_001578"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ8823302.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
     gene            complement(1532..2728)
                     /locus_tag="VIB71_001579"
     CDS             complement(1532..2728)
                     /locus_tag="VIB71_001579"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ8823303.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            complement(3264..5642)
                     /locus_tag="VIB71_001580"
     CDS             complement(3264..5642)
                     /locus_tag="VIB71_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEQ8823304.1"
                     /translation="MKTKKVIILVGLLLSSQLTLISCQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAYVADQYDPAKKAEKPAETPHTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNKM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKRLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPNLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            5846..6787
                     /locus_tag="VIB71_001581"
     CDS             5846..6787
                     /locus_tag="VIB71_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEQ8823305.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFAEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFENGDFQTLRSGEISLSSWEN"
     gene            complement(6762..6965)
                     /locus_tag="VIB71_001582"
     CDS             complement(6762..6965)
                     /locus_tag="VIB71_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEQ8823306.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
BASE COUNT         2078 a         1496 c         1260 g         2182 t
ORIGIN      
        1 tatgacagtt aaaaagccat aaaatgcaac aaagtatgca cctaagtatc attagcctaa
       61 gcacatgtaa tataaaaaag agaagcgtta gcttctcttt agtcttcgat taattgaata
      121 tctgccccta gtgctgttaa ttttgcaatg atactagcat agccacgtaa gataaattca
      181 atattagtaa tttctgtctt gccttcagct attagaccag cagtcactag agccgctccg
      241 gcacgtaaat cagtggcttt gacctgagct cctgtcaggc gagacggccc ttgataaaca
      301 atctgaccac caataactga gatatctgct cccatgcgca tcaactctgg cacatggtta
      361 atgcgctttt catatatagt gtcaataatc gttccacgac catctgcttt taacaacaag
      421 ggcgttaatg gctgttgcaa atcagtggca aaaccagggt aaggagaggt tttaattgta
      481 atagccttga gggattcttg cttttcaaca aagatagcat cctcttctac cgtcatacgg
      541 acacccattt cttctaactt agcaatgaaa ctctctaaat gctcataaag aacattagtg
      601 atcttaacac cttttccaat agctgccgcc aaagcgatat aagtccctgc ttcaatacga
      661 tcaggaataa cttggtgtct agtaccatgc aatttctgaa caccttgtat cgtaataata
      721 tctgtacctg ctccacgaat atgcgcaccc atgttattca aaagagtagc cacatcaata
      781 atctctggct cacgtgcagc gttttcaata accgttttac cttgagcttt tgttgccgca
      841 accatagtat taattgtagc accgacacta acggtgtcca tatagatatg agcgccatga
      901 attttttgac catttgtcga taaattcata ttttcaccct cataagacac ttcaactccc
      961 atagcctcga aggccttcaa atgcaagtca attggtcttg gtcctaaatc gcaaccacca
     1021 ggtaagccaa caactgcttg tccaaaacga cctaaaagac taccgtagaa ataataggaa
     1081 gctcgaagac tattaatctt tccgtaaggc atcgggatgt cttgcacccc tctagggtca
     1141 atttctaaag tatcaccatg atagtttact gttgctccca taagctccat gatttcaatc
     1201 agactatcta catcactaat agcaggtaca ccatcaagaa tcacaatatc atcggctaag
     1261 atgattgctg gaataagcgc aacaacactg ttttttgccc ctgaaactgc cacttctcca
     1321 gataaggctt ttccgccatt aataataatt ttacgcatac attcaaaact ttcttatact
     1381 agaattcaac cttttcattt tatcataaat catgaagcct gacaattatt gacgtcttaa
     1441 tttttaatca tcccttttaa aggcttattt aataacaaaa aagcagagta agattttttc
     1501 acttactcta cttttttaat aaagttgtcg tttataatac tgtttttaca gcttctacta
     1561 aagcatcaac cttatttaaa cgctcccatg gcaaatcaat atctgttctc cccatgtgac
     1621 cataggcagc tgtttgtttg taaatcgggc gttttaaatc aagcatttga ataatgcctg
     1681 ctggccgtaa atcaaagact tgacgaacag cagcttctaa aacagcttca ggaaccgttg
     1741 aggttccaaa tgtatccacg cgaacagaca caggctgagc caccccaatc gcataagcta
     1801 gttggacttc agctttggtc gcaaggcctg ctgccacaag gtttttagca atatagcgag
     1861 cagcgtaaga agccgaacgg tccacttttg tcgcatcttt tcctgaaaaa gcaccgccac
     1921 catgacgtga atagcctcca taggtatcca caataatctt acgtccggtc aatccagagt
     1981 ctccttgcgg acctccaata acaaaacgtc ctgttggatt aatgaagaac tttgtgtcat
     2041 catctaaata atctgctgga attacagcct tgatcacttt ttcaatcaca tcctgacgaa
     2101 tttggtcatt agtagcttct ggatcatgct gagtagaaat aacgactgta tccacacgaa
     2161 caggtttatc gtgttcatcg tactcaactg tcacttgaga tttagcatct ggacgtagat
     2221 aactaatctc acctgactta cgtaattccg ccaagcgacg cactaattgg tgagataagg
     2281 aaattggtaa aggcatcaat tctggtgttt cattgatggc aaaaccaaac atgagccctt
     2341 ggtcacccgc tccaatatgg ctaaggtcat cagtatcacc ttctctgctt tcgagagctt
     2401 cattaacccc ctgagcgata tctccagatt gttctacaag tgatggatgt actcccactg
     2461 attctgctga aaagccatat tctgcttctg tataaccaat ttctgcaatg gtgtcgcgga
     2521 ccacacggtt aatatcaatg tatgctgttg ttgagatttc tccaaaaaca tgaacagaac
     2581 ctgtgtaaac acaagtttct gcagccacat gggcttctgg atcttctgct aaaatggcat
     2641 ctaaaatagc atctgaaatt tggtctgcaa tcttatctgg atgcccttca gatacggact
     2701 cagacgtgaa aagtttacgt tctgacataa aaatgtcccc cctaatatgt tgattcttcc
     2761 tttttcagtc acattgacca caaagcaaga agttgcctac ccctttcttc ctagctgatt
     2821 gagcaagtca agtggccaaa accaacttag ctaatcagtt acggttttac tagtaaggca
     2881 actagctagt ccacctagtg gctagcgtcc attaaccaga caaagaatgt ctgacaatag
     2941 cgttgagtta caaagaatcc ggtctccttg ttgagaggat gtcaccacaa aataagcctt
     3001 agacgaagta atttagctaa agagagaacg actgttcccc aaatgaagtc aacaacgtct
     3061 caaaacattt cgttcaacag accgtcttat cgggactcaa taacaatcta ttataacatg
     3121 ttttagccat ttaggtgcca ttcttttcac tcattatcct atttatttca aaaaaacctc
     3181 aaggttattc ttgaggtttt cttgatagtc aacaatggtg tcattaagac gattcagttg
     3241 gatcgggtta ttcttagatt agtttagtca gcatggtttt gctcatcttt agcttcattt
     3301 tcatcctcat gttcatggtc gtgatcatct ttgtctctgt gctcgtgagc atgaccttct
     3361 tcatcttcat aggcatgatt atggttgtag tcatgtgatt ccgatgcttc ttgagcactt
     3421 tctttcgcct tagtagccat agctgctttt tcttcagctg ttccattacc taccatagaa
     3481 ccttcgtaaa ccgctgggaa gtttttcgca atggcttctg gaatatgttg ctcgttcaat
     3541 ttaaggtctg ccaatgggat attgttatga ctaatatcaa tgttagtaac tgtcttattg
     3601 ggtttagata ggttgacatt tgttaattgg tttttagaca cgcttaaaat gtcaagtgct
     3661 gtaaaattat taacaccttc tagagaagtc aactggttgc ctgtcacatc caagaaagta
     3721 agtgaccctt gcttgtcttt aagcacaagc gatttaattt ggttaccttc tgcttctact
     3781 ctgacaatga cgctacttgc ttcaatacct tcaagagatt gcaattgcgc acggttaata
     3841 gataggctag atagattagg attatttttc aagaaatcca aatgagaaac cttggtatca
     3901 ttgaccatta acgtttctaa gttgggtgct tgaagtgttg ctaagtcaac atcagcattt
     3961 cttgataaat caacaaccgt caatgattct ttatgagaaa cagggcttaa atctgtaatc
     4021 tgattattat caatgtgcaa ttcttgcaat tgatgtaacg atgccagtgg gcttaaatca
     4081 gaaatcttat tattactcaa tacgaggaat ttgagatttg gtaattgacc aagcggccta
     4141 atatcttcaa taccattatc agcagccgct actagagtta agtttttata tttgctcaag
     4201 aaactaatat ctttgagatt gttttgtgaa atatcaatgc cttctaactg tggcatatta
     4261 tccaaaaatc tataatcagt cacccctgtt tttgtcatta gtaaccgttt caatttttta
     4321 aattgcaaaa caggtgagat atctttgatt ggtgtaaagc caattcctaa agtttctaag
     4381 ttgggtaaca gtgaaagtcc tttacgttgc aaaggatctt tacggctacc caagtcaagt
     4441 ttgataaccg ttgctaacca ttctttcatc ttattcggat ctttttcatt tgatgggaat
     4501 ggggttggag catcgtgagt gcgaacgata tccaaaatca cttcttcatc aaaccctaag
     4561 gcacgcaagg tatccattcc aaccttatgt ttttccaatt cacgggcatg ctcaatagca
     4621 tgtggatctg gaatgtcttt tccgatttca atatcagata acatcaatac gtgtgcgtgg
     4681 tcatggtgag ggtattccaa accaagttta ccgtcttgtg tttccacacg tttaatagtt
     4741 gatggatcaa tccccaattt ttctgccaaa taagctaatt tttcttggta ttccttttca
     4801 cgttcagata gctctggtgt gtgaggggtt tctgctggct tttctgcttt tttagcggga
     4861 tcgtattgat ctgccacata tgcccagcca ccctgacgaa ggtccgcaaa agaaatagga
     4921 tgtaagtgac catcgtggtc cactaaaata ctgtcttttg ttaccccaac aataccttga
     4981 ccgttaaatt gaaaaccatc tgaggttggg aaatgcaagc ctggaatacc attagctgta
     5041 gctgttgaaa cagggctact ggtttgtggc aagcgagtag caacctgttt agcttgtgcc
     5101 tgtgtctgac ctgataagct tgacttcaaa atataatgga agtgatcatc gtggcgaacc
     5161 gtgtagccta aagcatcttc agccacaata tccgctgggt taaattcata atggtgatga
     5221 ggatctgcta ctttagaagt cccttgacta gctgcttgct gagcaacagc tggcttagct
     5281 aaacttgctc cttttggaat aaggtattca aatggacttc cctttaaatc ggcataaaaa
     5341 ataaaatgcg aatgaccatc atggtcaaca acgattccct gatctgtttt tgataagatt
     5401 tttgagtctt tggttaaaat aaacccatca tctgtaggaa aatcgacacc cgccacacct
     5461 ttgtgagtct tgtttgtctt tttgcttttt ttaatcggtt taattttgtt tgacgtcatt
     5521 cccttacgtg attgtttcgt tttaatggga tatgtaccat tacctcgtga ttgacaagat
     5581 atcaaagtca actgagatga taacaataga ccaactaaaa taataacttt tttcgttttc
     5641 attcaaccct cctttttatt taactggtta agtatatcac atcacttgtt tttcctcaag
     5701 ctctttttag gataactatt agttgttgac gagttggagc tctgaagctt caacaaacaa
     5761 tagtttctgt tgttagtagc attacacaaa aaaactaact tttcttttcc tttgaaaata
     5821 agatctttta taatatacta tacatatgaa aacatcagaa aaaatttatc aattactgtc
     5881 acaaaccgat gacttcgtca gtggggaata tctagcagat caactcagta tctctcgtac
     5941 atccgtttgg aaatccatca aaagtctcga aaatcagggg attcaaattg attctttaaa
     6001 acacaagggc taccgcatgg tacaaggtga tattttatta cccaaaacca ttagccaagg
     6061 gcttgggatg ccagtcacct atacccctca cagccaatct acccaattag atgccaaaca
     6121 aggaatcgaa gctcataaca gcgctccaag gctttaccta gctcctagcc aagaagctgc
     6181 caaaggacgc ctcgatcggc aatttttttc agctagcacc ggtggtattt acatgtccat
     6241 gtacctaaaa cccaatgtcc cttatgctga tatgcctcct tatacgatga tggttgcttc
     6301 cagtattgtc aaagctatct cgcgattaac aggcattgat acagaaatca aatgggtaaa
     6361 cgacatctat ctaggtaacc ataaagttgc agggattctg acagaagcca ttacttctgt
     6421 tgaaactggt ttaatcaccg atgtcattat tggggttggt ctcaactttt ttgtcaccga
     6481 cttcccagaa gcgattgctc aaaaggcagg ttctctcttt gccgaaaaac cgactatcac
     6541 gcgcaatgac cttatcattg acatctggaa attattctta tctattcctg tcaaggacca
     6601 tgtcaaagtt tacaaagaaa aatcacttgt tcttaataaa caagtgacct ttatagaaaa
     6661 tagtcaagaa aaacgtgcta ttgcgattga tctcacagat caaggacacc tcattgtaca
     6721 gtttgaaaat ggtgacttcc aaaccttgcg aagcggtgaa atcagtcttt cttcttggga
     6781 gaattagccg tttttaaaat ggttttagtc aattggttaa tggtatgcac tcttcttaaa
     6841 tccctaaaga gcaacaagcc ccaaaataag gcgaagagat aatttccaga gagcaacagg
     6901 tcattaaaaa aataggtttc aaaagcacat acaaaggcca taaaaagaaa ttgtcgaata
     6961 gtcatagctt tattataaca gaaaaaaatg attctatgaa gaatccacac agattg
//
LOCUS       DAUGUF010000051         6966 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUGUF010000051 DAUGUF010000000
VERSION     DAUGUF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6966
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.051"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(114..2432)
                     /gene="pcrA"
                     /locus_tag="VIB71_001583"
     CDS             complement(114..2432)
                     /gene="pcrA"
                     /locus_tag="VIB71_001583"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEQ8823307.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
     regulatory      2747..2833
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            2961..4283
                     /locus_tag="VIB71_001584"
     CDS             2961..4283
                     /locus_tag="VIB71_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEQ8823308.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFLGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     gene            4403..5638
                     /locus_tag="VIB71_001585"
     CDS             4403..5638
                     /locus_tag="VIB71_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEQ8823309.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVSVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRCHESWSLLFHQ
                     ITPIAKKQLHHTHYRIVKM"
     gene            complement(6008..6781)
                     /gene="cfa"
                     /locus_tag="VIB71_001586"
     CDS             complement(6008..6781)
                     /gene="cfa"
                     /locus_tag="VIB71_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEQ8823310.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQDALETALKS"
BASE COUNT         1975 a         1365 c         1290 g         2336 t
ORIGIN      
        1 aaatgcaact gatatgctcc taaaacttaa aattttttaa cttttatatg atacagaaat
       61 ctaaaaaaaa tgagcttcct actcacttat atagtaggaa gctcattttt ttcttatttt
      121 ttctcaatag gagcaacact tgctagtaat ttctttaaac caacttctgg aaatttgatt
      181 ttcaattcca tcgtttttcc ggagcctgaa acctcaagca cagtcccgtc tccccatttt
      241 ttatggtgag cgatatcgcc aatctgccaa gtgacctctt ctacagagct attagaacca
      301 aacggtaaaa ctgagctagt tgaagctgat ggtatcgtat gtgcctgcat tggctgtgct
      361 gattgtctta cttgagcctg ggcctttcga gcttgtaagg cttctgatag gctcatccct
      421 tgtccaaact gtgtgtgtgt ttcagtagaa aaacgcacac caaatgaaga ttgtgctggt
      481 cttgccaatc ctttataaga gagtagttcc tctgaaattt ctttcaagaa gcgtgttgga
      541 cggttataac tacttttacc aaagagggtt ctggtgttgg cattggtcat aaagagaact
      601 tcttcagctc ttgtgattcc gacataagct aaacgtcttt cttcttccaa ttcatctgga
      661 tcttcagagg cacgtgataa ggggaagaca ccttcttcca taccaattaa gaaaacaaca
      721 gggaactcca agcctttggc agcatgtagg gtcattaagg ttacttcagc agcttctgct
      781 tgggaatcat ctgtatcagc aatcagtgct aaatcgttta aaaaacgtcc caagcgatca
      841 acaccggttt cgtcttcttc ttgagaggca cttgactcgt caaaattttt ggtaacagat
      901 aagaattctt cgatattttc gatacgggct tggctttcca atgtattttg caggcgtaag
      961 ctatctaaat agcctgtttt ttctaacaaa gcttctgcta agtcggtgat actcatctga
     1021 tctaggtctt gacgtagctg accgagaata ttggccaagt ccatgatagc ttgtgctgct
     1081 ttacctttca agggggacat caatagattt gaagctgctt ctaataaaga ctggtcactc
     1141 tcataggcaa actgacgcag tttatcaagc gttcctggac caacacctcg tttaggctca
     1201 ttcacaatcc gctcaaaaga aatattatca gcagggttag caacaatggt taaataggca
     1261 atcaaatccc gaatttcttt acggctgtaa aacttggtgc ctccaaccat ggtgtaagga
     1321 atattggatt ttaagagtgc ttcttcaatg gtccgagatt gggcattggt acggtataaa
     1381 acagcgaaat ctttgaagtt ttttccaagc tcttgactca tattgctaat ggttgaggcc
     1441 acaaatactg cctcatctcg ctcatcattt gcccggtaat aaaccagttg ttccccatcc
     1501 gcattttgtg tccaaagttt cttaggacgg cgattacggt tattgttaat cacgtcgtta
     1561 gctgcttgca gaattttctt ggtagagcga tagttttctt ctaaaagcac taccttagca
     1621 tctgggtaat ctttttcaaa atcaagaata ttttgcatgt cagctccccg ccaaccatag
     1681 atagactgat cagcgtctcc aacaacgcaa atatttttaa agcgagaagc tagtaattta
     1741 attagctgat attgagcatg gttggtatct tggtactcat ccacatgaat gtattggtaa
     1801 cgctgctggt aataagctaa cacgtcagga ttagcgtcaa acaggcgtag cgtcatcatg
     1861 attaaatcat caaagtcaag tgcttcgcta cgtcgtaatt cttcctgata agctttgtaa
     1921 cacctcgcta cgatttgact atacatatca gcagcctgtg cctcgtatcc cttttcatca
     1981 agcaaatcat ttttagcgtt tgaaatagtt cctaaaatag aacgttcatt ccacttttta
     2041 gggtctatat ttaattgttt taaaatgcgc ttcatcaacg ttcgttgctc acctggatcc
     2101 acgattgtga agtttcggtt gtaaccaatg tgatcagcct cacgacgcag aatccgtaca
     2161 cacatggagt gaaaggtagc aattaaggta tctttagtag ctggatttaa ggccaaggcc
     2221 ctttctttca tttcacgcgc agccttatta gtaaaggtaa tagctaaaat attccaagga
     2281 ttgacaaatt tttcatcaat taaataggca atacgatggg tcagtaccct tgttttacca
     2341 gaaccagccc ccgccataat caataagggg ccttcagttg tttgaacagc ttgtgcctgc
     2401 cgatcattca ttccatttaa taaaggattc atgctttctc cttaatctcg ttcagtgaca
     2461 tctcttttat caaccttaaa attatatcat gtttccaaga aaaatagcaa agaagacccc
     2521 aaaagtaaag agattccttt tttctagttt aggatcagat atttaaaaat aatagcgatt
     2581 tcttaaagca ttccttattt ttttgctatt ttggttgact tcattcgttt tttaaggtat
     2641 gatagtccta atttaataaa ccgaatgatg tcatgcagga gaagaatttt tttcgccgaa
     2701 ggagttatac tctcaggtgt tcagtttttg aacgggactg tttgatggac ggacttctgg
     2761 agagacctta ttaggcgccg aaggggcaag gcatactgct caatctctca ggcaaaagga
     2821 cagaaggtaa aatacaaaca ccattaagaa cagtcttagt cttttttgtg tttgctgttt
     2881 tatcattgct tcagaagttg tctcaaagaa agagatagct tttttctttt ggcgtcttcg
     2941 atgactttta ggagagaaag atgatagcac tcgttaaatt aattgataac cttgtttggg
     3001 ggccgcccct cttaatttta ttggttggga cggggattta ccttaccagt cgtttaggat
     3061 taattcaaat cttaaaacta ccaagagcct ttaaactcat tttttcagat gacgaaggac
     3121 atggagatat ttcatccttt gctgctcttg caactgccct tgccgctact gtcggaactg
     3181 gtaacattgt tggggttgcc actgctatca agtctggtgg tcctggagcg ctcttttgga
     3241 tgtgggttgc cgcttttttg ggaatggcca ctaagtacgc tgaaggggta ctagcgatta
     3301 aataccgtac aaaggatgcc aacggtcata tttctggtgg tcctatgtac tatattgtta
     3361 atggcatggg gacaaaatgg aaacccttag ccattctttt tgcgggttca gggatcctag
     3421 ttgccctatt tggaatagga acctttgctc aagtgaactc gatcacctcg tctttaggtc
     3481 atagctttgg cttatcccca caaatggtca gtattgtttt agctatcttt gtggctgcca
     3541 ttatttttgg tggcattcat tccatttcca aagtggctga aaaagtcgtt ccttttatgg
     3601 ctatttttta tattctatct agtttagcag ttatttttag tcactaccaa cagctacttc
     3661 ctgttattcg tttagtcttt caatcagcct tcactccgac agctgctatt ggaggctttg
     3721 ctggaagtct catgaaggat gccattcaaa aaggaattgc acgcggtgtc ttctccaatg
     3781 agtctggact aggatctgca cctattgctg cagcagcagc taaaaccaat gaacccgtgg
     3841 agcagggact gatctccatg acaggaactt ttattgatac gattattatc tgtaccctaa
     3901 ccggcctatc tattttagta acaggccaat ggactgggca gctcgaaggg gctcctctga
     3961 cccaatctgc ctttgccact gtgtttggaa atttagggac ttttggccta accttttccc
     4021 tagttctctt cgcctttaca acgattttag gatggagtta ttatggagaa cgctgctttg
     4081 aattcctctt tggcattaca catctcacct acttccgtat tgtctttatc ttaatggtag
     4141 gcctaggagg cttccttaag ttagaactga tttgggtttt ggctgatatt gtcaatggtt
     4201 taatggcact tcctaacctg attgccctcc tagctctctc gccagttgtt attttagaaa
     4261 ccaagcatta ctttattaag taaacatgac gttagtacta cccagttata cctagtcttc
     4321 ttctgccaag ttcaagaagc taggcttttt tcttaatccc ctttttatgg tataatataa
     4381 agttgaaatc aaaggagtta ttatgacaca ggatccgatt gcaaatttaa aactagccag
     4441 aaagggccca atcgttagta ttattgtcta cttgttgctt agtgttgcca aattattagc
     4501 tggttatttg ttaaatgcaa gttcccttat tgctgatgga tttaacaatt tatcggatat
     4561 tgtgggaaat gtagccctgc ttattggtct tcacttagct agccaaccag ccgatgccaa
     4621 tcataaattt ggtcattgga aaattgaaga cttatccagc cttgtcactt cttttattat
     4681 gtttcttgta ggtttccaag tactgattca cacaattaaa agtatcttta gtggccagca
     4741 agttgatatt gaccctcttg gggctattgt cggtatcgtt tcagcttttg ttatgttagg
     4801 ggtttatgtc tttaacaaac gtctttccaa acgtgtaaaa tccagtgcct tagtcgctgc
     4861 ttctaaggat aatctagctg atgctgttac ttctatcgga acatcaattg ctattatagc
     4921 agcttctttg catttaccag ttatcgatca tatagctgct atgatcatta cgttctttat
     4981 tcttaaaaca gcttttgata tctttatgga aagttcgttt agtttatctg atggatttga
     5041 tagccgtcat ttgaaaaaat acgaaaaagc cattttagaa atccctaaaa ttgtctccgt
     5101 taagtctcaa cgagctagga cctatggtag caatgtctat cttgatattg tacttgaaat
     5161 gaatcctgat ctttcagtct atgaaagtca ctctattaca gagaaagtgg agcagttatt
     5221 gagtgaccaa ttttctattt atgacattga cattcacgtt gagcctgcca tgattcccga
     5281 agaagagatt tttgataatg tcgccaaaaa gctctaccgc tacgaaaaat taattttgag
     5341 taaggttcct gactatgacc actacattgc taagtctttc caactgattg atgcgaatgg
     5401 ccaaacagtt aactatgaac aatttttgaa ccaagaaatt tattatccaa gtaacttcaa
     5461 ccattttcag attgaatcca ttagtcaaaa aacgatgttg gtaacttacc aattaaatgg
     5521 caatcaacgt accagtattt ggaggtgtca tgaatcttgg tccttactct tccaccaaat
     5581 tacccctatc gctaagaaac aattacatca cacacactac cgtattgtaa aaatgtaaaa
     5641 acattacttc tcttataaca taactatact tcatgatatt cctaaagcga ttcctagtcc
     5701 caaaatgata agtgaaatag ttaaaaaaat ccctacaatt tgtttttaaa cagatcatag
     5761 ggattttttt aagaatacac gttttcatat tgaatcttat tagtttagga ggttaaacaa
     5821 gattcaatag tgacggttga acaatacctt aaattggtac atcatgttaa aggcaaaaag
     5881 ggctacaggt aactcattgt ttatgagagc atcacctcaa actctacaat ggtaagatat
     5941 ttaaaatctt tacctattct atatcctaat ataatcatct acctatacaa cacattactt
     6001 atacactcta tgacttaaga gctgtttcca aagcatcttg cacagcaata acttcatcgt
     6061 caacttgttg aacagtggtt gtcggattta gttggacacc aaccgcatgt gtgatagctt
     6121 tgttaagtct attgtaaaca tcaaatggtt tgatccccaa aaccttttta tctctttcta
     6181 aacgagtgtt ccaaatagct ttatttagtt tagctttagt atagatagta gcacggtctg
     6241 ttggctgtaa atcaggataa ttgataactt tttcctcaag tgctttaatt tcttgtactt
     6301 gagctttgat agcgtcaaca gatgcaaatg gatctataat acgaatgact aatttagtaa
     6361 tagcaaaccc catatcagta tgcgcttttt ctactttatg agttaattgg gttgtggaaa
     6421 atacgattgc tttgatagca tctgataatg cttctactct tgccccaatt gaactaaaat
     6481 catagatcgt ttcagtattg aagcgtatag aactcttcat gtgatcaaca gcatcgatag
     6541 ctttgttaac agtagcctca atatcagtac ctttagcttc atgtttaata gcttctaatt
     6601 gttgatgtcc ctcatcaagc ttttgcacta gagcatctct ttgaagattc gcttggttgt
     6661 tattcattaa aatagtatcg ggatttgaag catcatcagc taaaactgag tgcgtcatag
     6721 ttgaaaataa agctaatcca gcaacaactg ttgaaagaca gagaaggtgt ttgggtttca
     6781 tattattcct cctgaatata ataaacctat ttaaatagtt aagtgaagtt aaattaattt
     6841 ataagcgctt ataacgttat catactactt gtttttacta aggtcaatat ttctttaatt
     6901 tccagaaaat aagagaattt cgcaaaaata atcatttttt aatgtcatta aatgcctagt
     6961 attact
//
LOCUS       DAUGUF010000052         6782 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUGUF010000052 DAUGUF010000000
VERSION     DAUGUF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6782
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.052"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            59..709
                     /locus_tag="VIB71_001587"
     CDS             59..709
                     /locus_tag="VIB71_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ8823311.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGGKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            712..1380
                     /locus_tag="VIB71_001588"
     CDS             712..1380
                     /locus_tag="VIB71_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8823312.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVFIAGDKDTSYC
                     LLEK"
     gene            1389..2621
                     /locus_tag="VIB71_001589"
     CDS             1389..2621
                     /locus_tag="VIB71_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ8823313.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSMMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            2925..3803
                     /gene="mvk"
                     /locus_tag="VIB71_001590"
     CDS             2925..3803
                     /gene="mvk"
                     /locus_tag="VIB71_001590"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEQ8823314.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            3785..4729
                     /gene="mvaD"
                     /locus_tag="VIB71_001591"
     CDS             3785..4729
                     /gene="mvaD"
                     /locus_tag="VIB71_001591"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEQ8823315.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSISFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            4722..5735
                     /locus_tag="VIB71_001592"
     CDS             4722..5735
                     /locus_tag="VIB71_001592"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEQ8823316.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            5722..6711
                     /locus_tag="VIB71_001593"
     CDS             5722..6711
                     /locus_tag="VIB71_001593"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEQ8823317.1"
                     /translation="MTNRKDDHIKYALKYQSLYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKEVDYLLYGRLQQVN"
BASE COUNT         2146 a         1226 c         1404 g         2006 t
ORIGIN      
        1 ataaccgatc attgcagaga tttaagcatt tgttgagaaa atttgttata ataagcgtat
       61 gaaagaaaga ctagaacatt attctaccag ctctatatat agcggatttg aagtgtactt
      121 gccgttggta ctacagacaa taacagatgt gattattgct gagaatatca aaagcaaaaa
      181 agaaacgggg tttaaactat acgaacactt tacatcccgt attaaatcgg aagcttcgat
      241 gattgaaaaa tgtcaacgca aacagcttcc tctaacaagc aaatctgcgt taaaaatcat
      301 taaagatagt atcggtattc gcattatttg tggttttatt gatgatattt atcggatggt
      361 agacttgctc aaaagcattc ctggtatgtc agttaacact gaaaaagatt atattttaaa
      421 tgccaagcct aatggctata gatcatatca tctcattttg gaattagaaa cacattttcc
      481 agatatttta gggggaaaaa aaggatgtta ttttatagaa gtgcagttgc gaaccattgc
      541 tcaagactct tgggctagct tggaacatca aatgaagtac aaacatcaag ttgctaatgc
      601 agaaatgatt acaagagagt taaagcgttg tgcagacgag ttggcatctt gtgatgttac
      661 catgcaaacc attcgtcaat tgattcaaga aacgacggag gaagagtaac catgaaaatt
      721 ttgttagctg aagacgaatg gcagatgtct aatgttttga caactgccat gactcatcaa
      781 ggttatgacg ttgatgtggt ttttaacggt caagaggcaa ttgataaagc taaagacaat
      841 gcatatgata ttatgatttt agatatcatg atgccgatta agtctggcat tgaggcttta
      901 aaggagattc gcgcttcagg aaattgctca catattatta tgctgacggc tatggcagaa
      961 attaatgacc gtgttactgg actagatgcg ggagctgatg attatctgac taaaccgttc
     1021 tcattaaaag aacttttagc tagattaagg tcgatggaaa gacgagtaga aagttttact
     1081 cctcaggtat tacaatttgc tggtgtcaca ttaaatatta atgagcaaga attgagtgcc
     1141 ggtaatgcta tacgattagc ttctaaagaa ggtaaattaa tggccttttt aatgttaaat
     1201 caaggaaagt acttggatac taaaacactt taccaacatg tttggtcaga ccaagaagat
     1261 tatgatactt ctattgtttg ggtttatatt tcttatcttc gtcaaaaatt attagctatt
     1321 caagcaaatg tttttattgc aggtgataaa gatactagct attgtttatt agaaaaatag
     1381 gaggtgacat gtttaatcgt atccgtattc gttttatcat gattgcttct attgccattt
     1441 ttattatttt aagttcaatt gttggtatta ttaacacggc acgctgttac caaagtcaac
     1501 aagaaattaa ccgtatttta catttaattt cctcaaataa aggtaaatta cctggcacta
     1561 cggaaagctc taaacgactt ggaacgaaac tgtctgaaga tagcctaagc cagtttcggt
     1621 attatagtgt catttttaat gctaatggac atctactttc ttctaatact gctaatattt
     1681 cagctttaga tagagaagaa gcccaatatt ttgctagact ttttgctaag tctggggaag
     1741 aaaaaggcag ttaccgtcac caagatagtg tttattcgta cttgattact cagctgccaa
     1801 atgaagaaaa actggttgtt attttagata ctacctttta ttttcgtagt gtaggagatt
     1861 tattagccgt ttcaatgatg ttggcctttg gaggatttat cttttttgtt gttttagtga
     1921 gtcttttttc cggtatggtc atcaaacctt ttgttcaaaa ttatgagaag cagcgccgct
     1981 ttattactaa tgcaggccac gagttaaaaa caccactagc cattatctca gccaataatg
     2041 aattggtcga attaatgact ggagaatcag aatggaccaa gagtacaagt gatcaggtga
     2101 agcgattgac aggcttgatt aatcaaatga ttactttggc tcgtttggag gaacagccag
     2161 atgtggtatt acatatggta gacttttcag ctattgctca agatgcagct gaagatttta
     2221 agagtctggt tttgaaagat ggtaaacgtt ttgatttgac gattcagccg aatattatga
     2281 ttaaagcgga ggaaaagtca ttatttgaac ttgtgacaat tttagttgat aatgccaata
     2341 aatattgtga tcctaaaggc ttggtcaagg tatctttaac cactattgga agaagacgaa
     2401 aacgagcgaa attagaagtt tctaatacct atttggaagg aaaatccatt gattacagcc
     2461 gcttttttga acgcttttat cgcgaagacg aatcccataa tagcaaagaa aaaggttatg
     2521 gaattggttt atctatggca gaaagtatgg ttaagttatt taaaggaacg ataactgtaa
     2581 attataaaaa cgatgctatt gtttttacag tggtgatttg acttaaacat ttttcagtac
     2641 ctttagctag taataatgtc taggtaaagg tactaaacga tgcttaacca gcccatgagg
     2701 ctggttttta acgtttaatt tagtagaaga gtgatgaaga gtgattaaag aaggtagttt
     2761 gaaataagaa aatttttgtt atgatcctaa aaagagtaga tagtctttat tgttaatttc
     2821 ggtgaagaaa tgattttaaa aagatatatc atcgcatttt ctaatcattt agtgtaaaat
     2881 agtaaggtaa aagtttagaa gaattagtaa tgaaaagata aaaaatgaac gaaaacattg
     2941 gatatggtaa ggcacacagt aagatcattt tgataggtga gcatgctgtt gtgtatggct
     3001 acccagctat tgctttgcct ttaacagata ttgaggtggt ttgtcatatt tttccagctg
     3061 ataagccatt ggtctttgat ttttatgata ctctatcaac agccatttat gctgccttgg
     3121 attatttgca gcgactacaa gaaccaattg cttatgagat tgtttcacaa gtgccacaaa
     3181 agcgtggtat ggggtcttcg gcagccgttt ctattgcagc tattagagcc gttttttctt
     3241 attgtcaaga acccctctcg gatgatttgt tggaaatttt agtcaacaag gcagaaatta
     3301 ttgcccacac caatcctagt ggtttagatg ccaagacatg ccttagtgac catgccatta
     3361 agtttatccg aaacattggc tttgaaacta tcgaaatcgc cttaaatggt tatcttatca
     3421 ttgcagatac agggattcac ggtcatacac gtgaggccgt caataaggta gcacagtttg
     3481 aggaaacgaa tttgccctat ctggctaaac taggagcttt gacacaagcc cttgaaagag
     3541 cgattaacca aaaaaataag gtggctatcg gtcagctcat gacacaagcg cactctgctt
     3601 taaaggccat tggcgttagc atcagtaaag ctgaccaact tgtggaggct gccctaagag
     3661 caggtgcttt aggcgctaag atgacaggcg gtggcttggg tggctgtatg attgccctag
     3721 cagataccaa agacatggcc gaaaaaatca gtcacagatt aaaagaagaa ggagccgtaa
     3781 acacgtggat ccaaatgtta taaccgtaac atcctatgct aacattgcta ttatcaaata
     3841 ttggggaaaa gagaatcaag ctaagatgat tccttcgacc tctagcattt ctttgacttt
     3901 ggaaaacatg ttcaccacaa ccagcatttc cttcttacca gatactgcaa ccagtgatca
     3961 gttttacatt aacggtgtct tgcaaaatga cgaagaacat accaaaattt ctgctatcat
     4021 tgaccaattt cgccaacctg gtcaggcttt tgtaaagatg gaaactcaaa ataatatgcc
     4081 aacagctgca ggtttatcat caagttccag tggcttatca gccttggtta aagcctgtga
     4141 ccaactattt aacacccagc tagatcagaa agctttagct caaaaggcta agttcgcctc
     4201 aggatcatct tctcgttctt tttttggccc agtcgctgct tgggacaaag atagtggtgc
     4261 tatttacaag gttgagactg acttgaaaat ggccatgatt atgctggtct taaatgctgc
     4321 gaaaaagcca atttctagcc gagagggcat gaagttatgc cgcgatacct caactacatt
     4381 tgatgagtgg gtagaacaat cggcaatcga ttaccaacat atgcttacct atctcaaaac
     4441 taataatttt gagaaagttg gtcagttgac agaagctaat gccttggcca tgcatgccac
     4501 gacaaagaca gccaatcctc ctttttctta cctaacaaaa gagtcttacc aggctatgga
     4561 ggctgtgaaa gaactgcgtc aagaaggttt tgcttgttat tttaccatgg acgcaggtcc
     4621 aaatgtgaag gtcctatgtt tagaaaaaga cttggctcaa ctggcagaac gacttggcaa
     4681 gaactaccgt attatcgttt caaaaacaaa ggatttacca gatgtctaat tattgtgtgc
     4741 aaacaggtgg gaaactatac ctcacaggcg aatatgctat cttaacacca ggacaaaaag
     4801 ccttaattca ctttattcca ctgatgatga cagcagaaat tagcccagca gcccatattc
     4861 aattagcttc agatatgttt gcccataaag cgggcatgac gcccgatgcc tcttatgcac
     4921 tgattcaagc aacggttaaa acctttgctg actatctagg acagtcgatt gaccaactgg
     4981 agccattttc cctaatcata acaggaaaaa tggagcgcga tggcaaaaaa tttggcattg
     5041 gttcaagtgg tagcgtcacc ctcttaacct taaaggcctt atcggcctat tatcagatca
     5101 ctttaacccc agagttactc tttaaactag cggcttatac cttgcttaag caaggagata
     5161 atgggtctat gggggatatt gcctgtatcg cttaccagac tttagtcgcc tatacctcct
     5221 ttgaccgaga acaggtcagt aactggctgc agaccatgcc cttaaaaaaa cttctcgtca
     5281 aagattgggg ttaccatatc caagtcattc aaccagccct gccttgtgac tttttggttg
     5341 gctggactaa aatacctgct atttcaaggc agatgattca acaagtgaca gcgagcatta
     5401 ccccagcttt cttaagaaca agttaccagc taacgcaatc agctatggta gctttgcaag
     5461 aaggtcataa ggaagaactc aagaaaagtt tagcaggagc aagtcatctc ctaaaagagc
     5521 ttcatccagc tatctaccat cctaagctag taaccttggt agctgcttgt cagaagcaag
     5581 atgctgttgc taaatcttca ggttctggtg gtggagattg tggcatcgcg cttgccttta
     5641 atcaggatgc tagagatacc cttatttcca aatggcaaga agctgatatc gcattacttt
     5701 atcaagaaag gtggggagag aatgaccaac cgtaaagatg atcacatcaa atatgccctc
     5761 aagtaccaat cgctttataa tgcttttgat gacatagaac tcatacatca ttccttacct
     5821 agctatgatt tgtctgatat tgatctcagt actcattttg ccgggcaaga cttcgacttt
     5881 cccttttaca tcaatgccat gacaggagga agtcaaaaag gcaaagctgt caatgaaaaa
     5941 ttggccaaag tagcagcagc aacagggatt gtcatggtga cagggtctta tagcgctgct
     6001 ttaaaaaatc ctaacgacga ttcctatcgt ttacatgagg tggcagataa cttgaaacta
     6061 gccacgaata ttggtctaga taaacctgtg gcgctaggac aacaaacggt tcaagaaatg
     6121 cagcccctct ttttacaggt tcatgtgaat gtgatgcaag agttgttgat gccagagggt
     6181 gagcgcgtct ttcatacctg gaaaaaacac ctcgctgaat acgctagtca aataccagtt
     6241 cctgtcattc tcaaagaagt tggttttggc atggatgtca atagtatcaa gctagcacat
     6301 gacctaggca ttcaaacctt tgatatttca ggaagaggag ggacctcatt tgcctatatt
     6361 gaaaatcaaa gaggaggaga ccgctcttac ttaaacgatt ggggacaaac caccgttcag
     6421 tgcttgctaa atgcacaagg actgatggac caagtggaaa tcttagcttc gggtggtgtc
     6481 agacacccct tggacatgat taaatgtttc gtcctaggag cacgtgcagt gggactctca
     6541 cgcaccgttt tagaattggt cgaaaaatac ccaaccgagc gtgtgattgc tatcgttaac
     6601 ggctggaaag aagaattaaa aatcattatg tgtgctcttg actgtaaaac tattaaagaa
     6661 ttaaaggaag tcgactactt actatatgga cgcttgcagc aggtcaatta ggcttcatca
     6721 cctctacaat agtgccacct actacaaaga tgatagagct tttttagaac ataatataaa
     6781 at
//
LOCUS       DAUGUF010000053         6642 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUGUF010000053 DAUGUF010000000
VERSION     DAUGUF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6642
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.053"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            674..2431
                     /gene="pabB"
                     /locus_tag="VIB71_001594"
     CDS             674..2431
                     /gene="pabB"
                     /locus_tag="VIB71_001594"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEQ8823318.1"
                     /translation="MHRKTIIDFKELGQRYLFEEPLVELVAKSLDQVGPVIEKVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTIQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGINSWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQIGSVCVDRLCEVERYSTVWQMTSTIVGDLKADCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIALL
                     EQHLNRLKEAATYFAYPYNEKALQKQLSTYLENKDNAAYRLTISLSKDGKMRLSDQPL
                     EPLSADFLTAQLSLQDKDVTASPFTYFKTSYRPHIEQKSYEQVFYNQAGQLLETSIGN
                     LFIQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            2464..3030
                     /locus_tag="VIB71_001595"
     CDS             2464..3030
                     /locus_tag="VIB71_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEQ8823319.1"
                     /translation="MILLIDNYDSFTYNLSQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LIFSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            3063..4331
                     /locus_tag="VIB71_001596"
     CDS             3063..4331
                     /locus_tag="VIB71_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEQ8823320.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDGSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKELGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            4420..4616
                     /gene="ssrS"
                     /locus_tag="VIB71_001597"
     ncRNA           4420..4616
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VIB71_001597"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            4617..4689
                     /locus_tag="VIB71_001598"
     tRNA            4617..4689
                     /locus_tag="VIB71_001598"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4650..4652,aa:Lys,seq:ctt)
     gene            4830..5270
                     /locus_tag="VIB71_001599"
     CDS             4830..5270
                     /locus_tag="VIB71_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ8823321.1"
                     /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLTFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            5325..5795
                     /locus_tag="VIB71_001600"
     CDS             5325..5795
                     /locus_tag="VIB71_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEQ8823322.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERS
                     DHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLN
                     YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVVQKYSHKTIVLTN"
     gene            6080..>6642
                     /locus_tag="VIB71_001601"
     CDS             6080..>6642
                     /locus_tag="VIB71_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8823323.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDKIAVFSVPFDWNYL
                     SKGRVTAYTYGGITPYQKTSIPKNIPVNLWINGKQISVPYNEISTNKTTVTAQEIDLK
                     VRKFLISQHQLYSSGSSYKSGKLVFHT"
BASE COUNT         2131 a         1372 c         1238 g         1901 t
ORIGIN      
        1 agatagaaat atcactgata tagtctctgt aacaaaaaat aatcttcgta ttttaagcta
       61 tattacgatg cataatcctc tcattagtca atgaaaacgg ataaataaaa cacaattaaa
      121 tttaacataa ttaacaaagg cggtggttgt tgatcgaaat gaagatgcca tagctgagat
      181 acataatgta ataaatcaag taaataagac tgcgccaaaa ataaaagata gtgagcactt
      241 tgataattta ttaaagaact ctcataataa tctcgtaata aggtttccgt tgaattaaac
      301 aacataatat caataaccaa agatccattc tattatgatg aaatttattc tggagctgta
      361 aaagaactat tggctaaatg tttgtcttat gttgattatt tgaaagattt agctaagcaa
      421 tctaagacag aacctaattt tggtgaaaat cataaattat ataaaactat tatggatgag
      481 ttcaagagtc aagttaaaac actggcattg aaagataaaa aaatggaata ctgctcacct
      541 cacgataaga gtatattgta gtcaatcaag actgaacatt cttagtgaac gttcagtctt
      601 tttacgtggc caaaagacag ttgttacctg ttctcattag gcttagcaac cgcttttatg
      661 atataatttg ggtatgcata gaaaaacgat tattgatttc aaagagctcg ggcaacgcta
      721 tctttttgaa gagccattag tagaattggt agccaagtcc ttagatcagg tcggtccagt
      781 cattgaaaaa gtacaacact accaacagct gggctattac gtggtgggct atctcagtta
      841 tgaagcagct gctttttttg acaatgcctt acaaacccat aatgacagac taggcaacga
      901 gtaccttgcc tattttacag tgcacaaaac ctgtcaaaaa aaagacctac ctcttgatta
      961 tgacagcatt actatcccta accaatgggt cagcgcaact caaaaagaag cctatcaaaa
     1021 agccattgaa accattcacc gtgagatgca acagggcaat acttatcagg ttaactatac
     1081 cattcaatta actcaagaac tcaatgcagc tgacagctta gccatttaca ataaactcgt
     1141 cgttgaacag gctgctggct acaatgccta tatcgcccat gatgagtttg ccgttatttc
     1201 agctagtcct gagttgttct ttaaacaaga gggcaacagg ttaactacta gacctatgaa
     1261 aggcaccacc aaacgaggga ttaatagctg gctggatcaa caagaacatg actggctcca
     1321 agctgacggg aaaaatcgct ctgaaaacat gatgattgtg gatttgctcc gcaatgacat
     1381 gggaaaaatt tgccaaatag gcagtgtttg tgttgatagg ctctgtgagg tcgagcgata
     1441 ctctaccgtc tggcaaatga cctcaactat tgttggtgac ctcaaagcgg actgtgacct
     1501 gatagacatt ctcacagctc tctttccttg tggctctatc acgggggctc ctaaagtctc
     1561 caccatggca attatcacat ctctggagcc aaaaccaagg gggatttatt gtggaagtat
     1621 tggcatttgc ctacctgatg gtcgccgttt cttcaatgtt cccattagaa ccatccagct
     1681 cagtcataat caagctactt atggtgtcgg aggcggcatc acttggcaaa gcaagtggga
     1741 agacgaatac gaagaagtcc atcaaaaaac agcttttctc tatcggcaca aacaaatctt
     1801 tgacctcaaa acaaccgcca aggtggaaca caaaaaaata gctctccttg agcaacacct
     1861 caatcgcctt aaagaagcag ccacttattt tgcttaccct tataatgaaa aagctttgca
     1921 gaaacaactg tcaacctatt tggaaaataa ggataatgct gcctaccgct tgacgattag
     1981 tttatccaaa gatggaaaga tgagactctc tgatcagcct ttggagcctt tatcagccga
     2041 ttttctaaca gctcagctct ctttacagga caaggacgtg acagcttcgc cttttaccta
     2101 ctttaagacc agctaccggc ctcatattga gcaaaaatct tatgaacagg tgttctataa
     2161 ccaagcgggg caattattgg aaacgtccat cggcaatctt tttatccagc tgggtcagac
     2221 cctctacaca ccaccagtgg ctgtggggat tttaccagga ctttttcgcc aagagctgct
     2281 agctactggt caagctcagg aaaaagaggt gacactagct gatttaaaag aggctagcgc
     2341 tatttttgga ggaaatgctg tccgtggcct ctatcctctc aaccttgagc ttactcacct
     2401 tgatgccctc ttagctaaga gtcaagccta aactgccact catcttttgt tattaaggaa
     2461 cctatgatac tcttaattga taattacgat tcatttacct acaacctctc ccaatatcta
     2521 agtgaatttg acgagacgat tgtcttgtat aaccaagacc caaacttata tgacatggcc
     2581 aaaaaagcta acgctctaat cttttcacct ggtcctggtt ggcccaagga agccaaccaa
     2641 atgccaaaac tcattcaaga cttttaccaa acaaaaccta tcttaggagt gtgtctggga
     2701 caccaagcta tcgctgaaac tctaggagga accttacgct tggcaaaacg cgtcatgcat
     2761 gggagacaaa gcaccattga aacgcaaggc cctgctagtc tttttcgctc cctgccacaa
     2821 gagatcaccg tcatgcgtta ccattctatc gttgtggatc agttaccaaa aggttttagc
     2881 gtaactgcta gagactgtga cgatcaagaa atcatggcct ttgaacacca caccctgcca
     2941 ctttttgggc tacaatttca cccagaaagc atcggaactc ctgatgggat gaccatgatc
     3001 gccaacttca tcgcagccat tccccgttaa tctcatcccc caaaagaaag gaggacagtt
     3061 acatgcctga tcatttagcg ctcagaatgc gccccaaaac catttcagag gtcatcggac
     3121 aaaaacacct tgttggcgaa ggcaaaatca tccgtcgcat ggtggaagca aatagactat
     3181 cgtccatgat cctctatggc cctccaggaa tcggtaaaac ttccattgct tctgctattg
     3241 ctggtactac tagatatgcc ttccggacct ttaatgccac cattgacagc aaaaaacgtc
     3301 tccaagaaat tgcggaagaa gctaaatttt ctggtggctt ggtattatta ctagacgaga
     3361 ttcatcgcct tgacaagaca aaacaagatt ttcttttacc cttacttgag aacggcacca
     3421 ttatcatgat tggcgcaacc actgagaatc ccttcttttc agtgacaccc gctatcagaa
     3481 gcagggtcca gatttttgaa ttggaaccac tttctaacga ggatattaaa acagccattc
     3541 agctagcaat ttccgacaaa gaacggggat ttcctttttt agtgacaatt gatgatgagg
     3601 cgctagattt cattgttacc gccacaaatg gagacctacg atctgcttat aattccttgg
     3661 atctagcagt catgtctact tctcctaatg aagatggtag ccgtcatatt agtctagaga
     3721 caatggaaaa tagtctgcag cgtagttata ttaccatgga taaaaacggg gacgggcatt
     3781 atgatgtttt atctgcctta caaaaatcca ttagaggttc tgatgtcaat gctagcctgc
     3841 actacgccgc tcgtttagta gaagctggag acttgcctag tttagcaaga cgattgacca
     3901 ttattgctta cgaagatatt ggcttagcca accctgacgc ccaagttcat accgtcaccg
     3961 cactagatgc cgctcaacgc attggttttc cagaagctcg tattcttatc gctaacgtgg
     4021 tcattgattt ggctctatca cctaaatcaa attcagctta tttagctatg gatgcagctt
     4081 tagctgattt gagaacatca ggtaacctcc ccattccaag gcatttgaga gatgggcatt
     4141 atgctggcag taaagaactg ggcaatgcca aagattacct ctaccctcac gcctatcctg
     4201 aaaaatgggt caaacaacaa tacctaccag ataaattagt aggacatcat tattttgaag
     4261 ccaatgaaac cggtaaatac gaacgcgcac ttggttcaaa taaagagcgt attgacaagc
     4321 tctcagactg actgctagtt ttaaaaatcg caaccgattt caaaaatcga taattttgct
     4381 tgaaaaaatt ttaaaaagtg gtattataaa agtacagaaa cattgctgtg gcatacgaat
     4441 ccacatctaa gtgttgaccg actatttctt tgtattttcg ggaaacaaag actctttcta
     4501 gtctgcaagc cgtttcacgc ggacgcaact tccaagaaag agcgcgttac ccacctgctt
     4561 atactgcgcg ggctcaatac aaaaacgtgg atcaccggtg ccaatacagc attcttgcct
     4621 ccttagctca gttggtagag cagtagactc ttaatctatg ggtcacaggt tcgagccctg
     4681 tagggggtat acaactatgc atgaaaaaac ctttgtttaa aggctttttt tgcttgtcag
     4741 aagaggattt gttccatcat ttatccccgc agtaattttt ttatggtatg ataccaatta
     4801 aagcgcttaa gattaaggtg gagactgtta tgaaaataat tgagtacaaa ggaaattaca
     4861 gagatgacct catttttatg gtcttggaag caaaaaatgc cttaaggaga attcccagca
     4921 ttaacccgga tcttttgaca attgaaacaa gttatttgga aaaaggggat tgtttttggc
     4981 tagcggtcaa tgaagaaagt cgtgttattg gctcaatcgc ttattcttct attcccaaaa
     5041 caaatgaggt cttcttgcac cgtctcttca tcaaaccaag cttaaaacat caaggcattg
     5101 gcagtcaact tctgacgttt gcagaagatt atctaaggaa aatcggcaag agtcatgttc
     5161 gtatccactt aggtcaacct aaagaacaat ggtttgagtc ttatcggttt tatcctaaac
     5221 atggttatca attttatgat gacacgcatc tcatcaagaa actaatctaa acacagttca
     5281 taccctttat agtcatttca tacgtcattt ttaggaggta tccattgaaa attgccatca
     5341 ttggacatag tggctctgga aagtcaacct tagcacgatt tttaggccaa cattaccatt
     5401 gtgaggtatt ccatttagac caactacact tctcatcgaa ctggcaagaa cggtcagatc
     5461 atgacatgat agctgattta tcaacatgcc tgctcaaaca agattggatt attgagggga
     5521 attatgccaa ttgtctctat gaagagcgca tgagtgaagc tgattacatt atctatgtta
     5581 atttcagtcg gtttcattgt gtctatcgag catttaagcg ttatttaaac tataggggaa
     5641 aaacgcgtcc tgatatggct gacaactgtc aggaaaaatt tgacgttgcg tttgtgaaat
     5701 ggattctact agatggacgt tcaagaaacc aattaaaaaa ataccaatcc gttgtccaaa
     5761 aatactctca taaaaccatt gtcttaacaa attaaaagca gctaagtcat tatatgaata
     5821 cgatcaacta attagagtgc aaaactaaaa taaccacggg taatccgggc tattcagact
     5881 gaaagccttt gtttaaaggc ttttttgctt gtttcataac taatcggctt aattaaaagc
     5941 gtcaatccac ctttagtatc atgtctcaat tttcatttga tagtcagcaa gtatatctac
     6001 aaaattgtta atgattattt cttttgaaag tgttatatta aaacataata aaataataac
     6061 tcctgaaaag aggctattta tgaaaaaaac aaaacttatt ttttctttta cttcaatatt
     6121 cattgcaata atttctcgtc ctgtgtttgg attagaagta gataataatt cccttctaag
     6181 gaatatctat agtacgattg tatatgaata ttcagataca gtaattgatt ttaaaaccag
     6241 tcataactta gtgactaaga aacttgatgt tagagatgct agagattttt ttattaactc
     6301 cgaaatggac gaatatgcag ccaatgattt taaagctgga gataaaatag ctgtgttctc
     6361 cgtcccattt gattggaact atttatcaaa aggaagagtc acagcatata cgtacggcgg
     6421 aataacaccc taccaaaaaa cttcaatacc taaaaatatc cctgttaatt tatggattaa
     6481 tggaaagcag atctctgttc cttacaacga aatatcaact aacaaaacaa cagttacagc
     6541 tcaagaaatt gatctaaagg ttagaaaatt tttaatatca caacatcaat tatattcttc
     6601 tggttctagc tacaaaagtg gtaaattagt ttttcataca aa
//
LOCUS       DAUGUF010000054         6498 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUGUF010000054 DAUGUF010000000
VERSION     DAUGUF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6498
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.054"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            181..1488
                     /gene="eno"
                     /locus_tag="VIB71_001602"
     CDS             181..1488
                     /gene="eno"
                     /locus_tag="VIB71_001602"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEQ8823324.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMITLDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(1963..2994)
                     /locus_tag="VIB71_001603"
                     /pseudo
     CDS             complement(1963..2994)
                     /locus_tag="VIB71_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3261..3821)
                     /locus_tag="VIB71_001604"
                     /pseudo
     CDS             complement(3261..3821)
                     /locus_tag="VIB71_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            3854..>6498
                     /locus_tag="VIB71_001605"
     CDS             3854..>6498
                     /locus_tag="VIB71_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ8823325.1"
                     /translation="MLQTVTVTKDQQNPISITLSEDQAKSLKNKEKLKVSIKQKQSKK
                     TSKDFFFEVGIDPKVEAKQKEKLLELDKVKKQIEDSINGDAWLPEKPEGEKPVQNTNK
                     ELQLQELNKKYQMAKEAIESATTLDDVETQFDKYTKVGDKDKYPDSLRNQYTQGDKDK
                     EIEKAKKSLGDLSDKVNGKIEEDKWLSAEVKKKQQQELEARKQKVNDSLKGSDSLKSL
                     RETVEKASSKNQKKPESFEDVYVPGNEETEKTKVRDILQKTYQKTEQNIETDPWLSPE
                     QKKAQKENAKTRLDAGLKAVETTESLDKLKEVESDFLDKEKNPDSIPNQHKAGTPEVA
                     RKTFLDNFEKEAKKEIESIKNDVTLTDAEKATAKAKVEAQLQEAKGKAKESKSFDDLK
                     NIQDKFNSELPHTPGKPLKDQQSDAIAELEKKQQEIEKAIEGDKTLPRDEKEKQIADS
                     KERLKSDTQKVKDAKNADAIKKVFEEGKVNIPQAHIPGDLNKDKEKLLAELKQKAADT
                     EKAIDSDKTLTAKEKEEQKAKTKEELQKATEAVGAIDNREELDKKVPELKKAIEDTHV
                     KGNLEGVKNKAIEDLKKVHDETVAKINGDDTLDKATKEAQVKEADKAYGDGVTAIENA
                     HVIGKGIEARKDLAKKDLAEAVAKTKALIIEDKTLTDDQRKEQLSGVDTEYAKGIENI
                     DAAKDAAGVDKAYSDGVRDILAQYKEGQNLDDRRNAAKEFLLKEADKVTKLINDDPTL
                     THDQKVDQINKVEQAKLDAIKSVDDAQTADAINDALGKGIENINNQYQHGDGVDVRKA
                     TAKGDLEKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTADGVNQE
                     LGKGITAINKAYRPGEGVKARKEAA"
BASE COUNT         2307 a         1136 c         1329 g         1726 t
ORIGIN      
        1 tacaataaaa taccaatttg aaaattttcg gtaaatgtgt taaaaaacaa gaaagaaagt
       61 gatttttctt gcaaaaaaca aaggaagctt ttcatgagat tgctttttaa gttgattaaa
      121 ggcctagttt gtggtattat gaacatgtaa aatattaaaa ctcataagga gagtattaca
      181 atgtcaatta ttactgatgt atacgctcgc gaagtccttg actcacgcgg taacccaaca
      241 cttgaagtag aagtttatac agaatcaggt gcattcggac gtggtatggt tccttcagga
      301 gcttcaactg gtgaacatga agccgttgaa cttcgtgatg gtgacaaatc tcgttacctt
      361 ggtctaggta ctcaaaaagc agttgataac gttaataaca ttatcgctga ggcaatcatc
      421 ggttacgatg ttcgcgatca acaagctatc gaccgtgcaa tgatcactct tgacggtact
      481 cctaacaaag gcaaacttgg tgctaatgct attcttggtg tttctatcgc tgttgctcgt
      541 gcagctgctg actatcttga agtgccactt tacacttacc ttggcggatt caacactaaa
      601 gttcttccaa ctcctatgat gaacatcatc aacggtggat cacactcaga tgccccaatt
      661 gcattccaag agttcatgat catgccagtt ggtgcaccta ctttcaaaga aggtcttcgt
      721 tggggtgctg aagttttcca cgctcttaag aaaattctta aagaacgcgg acttgttaca
      781 gctgtaggtg acgaaggtgg atttgcacct aaatttgaag gaactgaaga cggtgtagaa
      841 actatcctta aagctattga agcagctggt tacgaagctg gtgaaaacgg cattatgatc
      901 ggttttgact gtgcatcatc agaattctac gacaaagaac gtaaagttta cgactacact
      961 aaatttgaag gtgaaggcgc tgctgttcgt acatctgcag aacaagttga ttaccttgaa
     1021 gagttggtta acaaataccc aattattact atcgaagatg gtatggacga aaacgactgg
     1081 gatggttgga aagttcttac tgaacgccta ggcaaacgtg ttcaattggt tggtgacgac
     1141 ttcttcgtta caaacactga ataccttgct cgtggtatca aagaaaatgc agctaactca
     1201 atccttatca aagttaacca aatcggtact ttgactgaaa cgtttgaagc tatcgaaatg
     1261 gctaaagaag ctggatatac tgccgttgta tcacaccgtt caggtgaaac tgaagattca
     1321 acaatcgctg acatcgcagt tgcaacaaac gctggccaaa tcaaaacagg ttcattgtca
     1381 cgtacagacc gtattgctaa atacaaccaa ctacttcgta tcgaagatca acttggtgaa
     1441 gttgctcaat acaaaggtat caaatcattc tataacttaa aaaaatagac ggtaagacag
     1501 aaatcggtca ttcgtagaat gcgatttcgt cgtcgcacct ccgtcaggct gactaggttg
     1561 gtcacgacaa aaggagtgga catccagtca gctacgacgc aaaagttaaa gaatagaaag
     1621 cttgggaaaa tcccaagctt tttgctttct aaatagtaaa aatttactgt gggctaattt
     1681 atcctgagct aatgtattag cgaggtaaag ttactgaaga agacttggat ttgtactgcc
     1741 tctaaaaagt tggacactat attttaaata caggactaag tccttttata ccaattgtca
     1801 agcacatcaa ggttttaact gaaaaaatgt tttagacaat agcctaggtt tagctgttgt
     1861 cttacttgtt gtgctctgat tagcataaaa aagtgtacaa gaaaaaaacc ttgcctagta
     1921 tttttaagat caaggtgtta caatgataga gtaacaacga ctttaatgat tttgggtcga
     1981 agcgtaattg taaagtttgt tatgcgttat gaggtaaagc attgtcctga caaggcaatg
     2041 tctagaggca atcgtatgtg gcttggttga agctgtttac gattgccttt ttcgtttctc
     2101 atagaagtct gcgatatgac aaggattggt atgactagca gaagcaatgt catggataca
     2161 cttgaaaaga atctttggag cataaggatt cccacgttcg gtaatgtgct cttgagctag
     2221 acagttgcca gactcataat gtctaaagtc aatcccaatg aaagcattaa tttgattagc
     2281 agattgaaaa cgacgaatag caccgagttc gtcaataata cttgttgcag ttgtttctgc
     2341 gatacttgga atagagcgta gaatcttgtc ttctggtaaa ggttgagcca acgccaccat
     2401 cttatcaaaa atagcttgac gacgttcaga aagtctaagt aattctttgg cataatagcg
     2461 aacctcttct atcatcggag aggttttcgt aacagtaaaa taagactgct tggctaatga
     2521 gacaagtttt tccactaagt agatcccacg cttgtcagag atacgtttag aggtagattg
     2581 acggatgata gctgacaatg ctttgtcagc tagctccagt acaaagctat tacatggaaa
     2641 agccgttacc acattccagt attactcacc agttggtgca aataagatgt gttccagttc
     2701 aggaaaagtg acttgtaaga tcttgtgaag gcgattctta actctcgaac aatattatcc
     2761 tcagtctcaa gttttgatag aagcgactca agtcacgtag cagctgataa acttcttcct
     2821 ggacgtaagt tggttttcta actagaataa attgagactg agccaatttt tcagtgtcta
     2881 acttatccgc tttacgcacc cgtagactat ctagttttct aaaggattga gttgtgtata
     2941 agcgtagcca tttttctcaa ggaaggactg aagccgacga gaatagactc ctgttgtgat
     3001 ggtctccctt ttgtctttta aacaatagta tagccgtttt tcaaaatgtt attaatgatt
     3061 ttttccttta ttctagaaga ataagtctga tactgtttct tcttaataat ctcaatgccc
     3121 taacaatcca tcagtcgaac ggtatttctc aaattactgc agttgactct tgcgttcagt
     3181 tccctcacct tgtggatgcc gtttagaaca atattagctt gctgagcctt ttggtaatgt
     3241 gaacaaagca tctttatcac tcaaggagaa gacaggttct tgtggtaagt gtccaacaag
     3301 gtcacgataa actcatcgta ccgtttttgg cagaagtcta gaaatgcctt atgaatgtaa
     3361 gcctcagaaa cgtctctaaa actaaacaag aaatacaaga acaaatgccc ttgattctgg
     3421 tacaaatgct gtatcaggtt caggtattgc ctatctgcga taatgacact ctgcttttcc
     3481 ttaacaatat ctttgaaagg aatgatttcg acattgacag gcataaccgt tgcaatagct
     3541 ggcgggaagt aaatcgagag tgcattggtc atcaaatcca gcgcagcagt gttattggtc
     3601 aaaagataga caggtatcgg tggcaaatat gtttttagga gttcctctaa ctgtatcgtg
     3661 aagagcagta aatgatagga cggcagtttc cccacgatac cttctgcgct catccattcc
     3721 tcaacgatgg tttttagagt attgtagaag ctcttgtttc gtttttgctg tcttctgagg
     3781 taatggaaca agtgtatatc aggtaacaaa cttcgaaggt gatgagataa gccttttcaa
     3841 ctctagggga gagttgttac agacagttac agttacaaaa gatcaacaaa atcctatatc
     3901 aataacttta tctgaagatc aagccaaatc tttaaaaaat aaagaaaagt taaaagtaag
     3961 cattaaacaa aagcaatcaa aaaagacttc taaggacttt ttctttgagg taggaattga
     4021 tcctaaagtt gaagcaaagc aaaaagaaaa actcttggaa ctagacaaag ttaaaaaaca
     4081 aattgaagac tcaatcaatg gtgatgcatg gctaccagaa aaaccggaag gcgaaaaacc
     4141 agtacaaaat actaataaag aattacagtt acaagaactg aacaagaagt atcagatggc
     4201 caaagaggca attgaaagtg ctacaactct tgacgatgtt gaaactcagt ttgataaata
     4261 cacaaaagtt ggagataaag ataaataccc ggattcttta cgtaaccaat atactcaagg
     4321 agataaagat aaagaaatag aaaaagctaa aaaatcactg ggtgatttaa gcgataaagt
     4381 aaatggaaaa attgaagaag ataagtggct atctgccgaa gttaaaaaaa aacaacagca
     4441 agaattagaa gcgcgtaaac aaaaagtaaa cgactctctt aaaggatctg atagtttaaa
     4501 atcattgaga gaaacagtgg aaaaagcttc ttctaaaaat cagaaaaaac cagaatcttt
     4561 tgaagatgtt tatgttcctg gaaatgaaga aactgaaaaa acaaaagttc gtgatatact
     4621 tcaaaaaact tatcaaaaaa cagagcaaaa tattgaaaca gatccatggt tgagtccgga
     4681 acagaaaaaa gctcaaaaag aaaacgctaa aacaagatta gatgcaggtt tgaaagctgt
     4741 cgaaactaca gaaagcttag ataaacttaa agaagttgag agtgacttcc ttgataaaga
     4801 aaaaaatcca gattcaattc caaatcaaca taaagctgga actcctgaag ttgctcgcaa
     4861 aactttctta gataactttg aaaaagaagc taaaaaagag attgaatcaa ttaaaaatga
     4921 cgttacatta acagatgctg aaaaagcaac agctaaagct aaagtagaag cacaacttca
     4981 agaagctaaa ggtaaggcta aggaatcaaa atcgtttgat gatttgaaga acattcaaga
     5041 taagttcaat tctgaattac cacacacacc aggtaagccg cttaaagatc aacaatctga
     5101 tgctattgca gaattagaga agaagcagca agaaattgaa aaagctattg agggtgataa
     5161 aacattacca agagacgaaa aagagaaaca aattgctgac tctaaggaac gcttaaaatc
     5221 tgacactcaa aaagttaaag atgctaaaaa tgctgatgct attaaaaaag tatttgaaga
     5281 agggaaagtg aatattcctc aagcacatat cccaggtgat ttgaacaagg ataaagaaaa
     5341 acttcttgca gagttgaagc aaaaagcagc tgatactgaa aaagcgattg attccgataa
     5401 aactttgaca gcgaaagaaa aagaagagca aaaagcgaaa acaaaagaag aacttcaaaa
     5461 agcaacagaa gctgttggag caattgacaa tcgtgaagaa ctagataaaa aagtcccaga
     5521 acttaagaaa gctattgaag acactcacgt taaaggtaat cttgaaggtg ttaagaataa
     5581 ggctattgaa gatcttaaaa aagttcatga cgaaacagtt gctaagataa atggtgatga
     5641 tacccttgac aaagctacta aagaagctca agtgaaagaa gctgacaaag cttacggtga
     5701 tggtgtcaca gcgatcgaaa atgcccacgt tattggtaaa ggtatcgaag ctcgtaaaga
     5761 ccttgctaag aaagaccttg ctgaagctgt tgctaagaca aaagctctca ttattgaaga
     5821 caaaacgctt actgatgatc aacgtaaaga acagttatca ggtgttgata cagagtatgc
     5881 taaaggtatc gagaatattg atgcagctaa ggatgctgca ggtgttgata aagcatatag
     5941 tgacggtgtt cgtgacatcc tggcacagta caaagaaggt caaaaccttg atgatcgtcg
     6001 taatgctgcc aaagaatttc ttcttaaaga agcagacaaa gtgacgaaac taatcaatga
     6061 tgatccaacc ttgactcatg accaaaaagt tgatcaaatc aacaaagttg aacaagctaa
     6121 gttagacgca atcaagtctg ttgatgatgc tcaaacagct gatgctatca atgatgctct
     6181 tggtaagggt attgaaaaca tcaacaacca ataccaacat ggcgatggcg ttgatgttcg
     6241 taaagcgact gccaaaggcg atcttgaaaa agaagctgct aaagtgaaag ctcttattgc
     6301 taaggatcca accttgactc aagctgataa agacaaacaa acagcagcgg ttgacgcagc
     6361 taagaacaca gcaattgcag cggttgataa agcgacaaca gcagatggtg ttaaccaaga
     6421 acttggtaaa ggcatcacag ctatcaacaa agcttaccgt ccaggtgaag gtgttaaagc
     6481 acgtaaagaa gccgctaa
//
LOCUS       DAUGUF010000055         6185 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUGUF010000055 DAUGUF010000000
VERSION     DAUGUF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6185
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.055"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..1619
                     /locus_tag="VIB71_001606"
     CDS             <1..1619
                     /locus_tag="VIB71_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ8823326.1"
                     /translation="KELTQLLTLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELT
                     LEVQWFITVNEIIESLGILVVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKV
                     RAIIAITALLLSYILCLATVFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAF
                     VVSLLKENKKRLYRPLSNIIYPKFNYRIATKNKLLTVLGGLLTVTVSVAGMMVMLYAY
                     SLNGIERLTPSAIEYNVESENGQVNVTTILENDQVSLVDVDLLRLNTNPEVTITESGQ
                     TIPYFDIINYSDYKELMKAQGRINSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVT
                     VKQVSTHNVFSFSTSVTTLVVSDKLYAKLSSCFPEKEMTIRTFNGNSIRSSEAFYNQF
                     SMVPDVISSYSKEYTVKTANIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYG
                     YLSKLGYSKKMIHRILRYETGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIML
                     SLLLCLLFFLIIYGTFYVLTLRSVTSIIKN"
     gene            1659..3221
                     /locus_tag="VIB71_001607"
     CDS             1659..3221
                     /locus_tag="VIB71_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ8823327.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNSILFNFLFLMVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWIVLMKVLVKDFL
                     LFFIIVDASTLFCLVVISCIFYYLENSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     DVLQNIIAIKNLLSLENSNITHGFIVNELNDLVSGIRDEMDTYHPIVPANQTMKENIQ
                     SLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSL
                     TIQSDIIIIEESNQVVEKVHSINYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLP
                     IDWKLCYEDFIN"
     gene            3202..3807
                     /locus_tag="VIB71_001608"
     CDS             3202..3807
                     /locus_tag="VIB71_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8823328.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(4359..5939)
                     /locus_tag="VIB71_001609"
     CDS             complement(4359..5939)
                     /locus_tag="VIB71_001609"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEQ8823329.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLIAVCDNLEEHFNTFTDAQKIFEDAYQDQGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSHQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKVLNAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(5952..>6185)
                     /locus_tag="VIB71_001610"
     CDS             complement(5952..>6185)
                     /locus_tag="VIB71_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8823330.1"
                     /translation="YLNGEFRNGIIKIAQGGTQIYVNYSSVEQLKINIPTLKEQEAIG
                     NFFQTLDQQIAQSEEKLTELKALKQTLLNRLFV"
BASE COUNT         2012 a          891 c         1093 g         2189 t
ORIGIN      
        1 aaaaagaatt aacacaatta ctgactttag aaaatcttgt tattctagtt ttaagttact
       61 tggtaagttt actattggga ccgaccttat attttttagc ggtactggta attactcatc
      121 tattggaatt aacattggaa gttcagtggt ttattacagt taatgagatt atagagtctt
      181 taggaatatt agtcgtagtt tttctgatta atgtcatcac aaatggactt atcattagta
      241 aacagtcttt gattgaattt gttaatttct caagaaaggc tgagaaaaaa attaagataa
      301 gaaaagtcag agctattatt gctatcactg cattgctatt gtcatatatt ttatgtttgg
      361 cgacagtgtt ttcatccaca cgaaatatgc tattaagcat agggatggta ccggtttctc
      421 tattgataat tgtcttagtt gttttaggaa cagtgttcac catcagatat ggattggctt
      481 ttgtagtttc gttgttaaaa gaaaataaaa aaaggttata ccgtcctctg tctaatatca
      541 tctatcccaa atttaactat cgtattgcaa caaaaaataa attattaaca gtcttgggag
      601 gtcttttaac agtaaccgtt tcagttgccg gaatgatggt aatgctctat gcttattctc
      661 ttaatgggat agagaggttg actccatctg ccatagaata taatgttgaa tcagaaaacg
      721 gtcaagtcaa tgttacaact attttagaga acgaccaagt gagcttggtt gatgttgacc
      781 tattgagatt gaacactaac ccagaagtaa ctatcacaga atctgggcaa acaattcctt
      841 attttgatat aattaattac agtgattata aagagttaat gaaagctcaa gggagaataa
      901 attctattga aggtagtaag tcactcccat tgttaataaa ttattatcca acagaaatta
      961 gccttggaaa aacctttaac ttaggaaatg catatgatgt tactgtaaaa caagtatcaa
     1021 cgcataatgt ttttagtttt tctacaagtg tcacgacctt ggttgtttct gataaattat
     1081 atgctaaact tagttcttgt tttccagaga aagaaatgac aattaggact tttaatggaa
     1141 attcgattag gtcaagtgaa gcattttaca atcagtttag tatggttcct gatgttatca
     1201 gtagttatag taaggaatac acagtaaaga ctgctaatat tgcgacttat atctttataa
     1261 ctttcctatc catactcttt attatttgta caggtagtat tctgtacttt acaagcctca
     1321 tcgaaatcat ggaaaataaa gaagaatatg gctatctaag taagctaggt tatagtaaaa
     1381 aaatgattca tcggattctt cgatatgaaa caggtatact tttccttatt cctgtattca
     1441 ttgggattgt aaatggtggt atgttgctta tttactataa atatttattc atggatacat
     1501 tggtagcagg caatatcata atgttatctt tattgctttg tctgcttttc ttcttgataa
     1561 tatatggcac attttatgta ttgacattgc ggtcagtgac atccataatc aaaaattaat
     1621 tttaaaaatc ttttaacttt aacgattaag taaataatat gataagaata aaaaacataa
     1681 caaagagtaa gttctttggg actgcaataa tcttgttgca acaattaata gccttgttaa
     1741 ttttggtcta taatcgagag aacctgtctc ttcttttctc tgaaaaagta gctcttgtaa
     1801 tgacccttat tgatacagct tttatttggc tggcaacaat attacgccaa aaacaaggtg
     1861 atatttttaa aaggattatt tctatcatct ccttaacaat ttggcaatac ttagtatctg
     1921 tgctgacaag aggaactcct ctctttttaa gcagtggact acagattata ttgctctatt
     1981 gttataccgt tgagattact aatttaatat tatatgggca caaacaattt aaagataagt
     2041 tagataaggg cttgttaata attatttttg tttctataac tagccttttt gttaatagca
     2101 ttttatttaa ttttttattc ctgatggttt ttactatttt acacctgtat ccgttactag
     2161 ttatagtgct atattatagg tcctttaggc aacaaatatc agttgttaga cgttcattga
     2221 tactattttc tttacttttg ctggtaatac ttggtagtga actttatgga gaaatgctag
     2281 atgttaatca agcctttaat aatttgggat ggtatctgtt tccccttata atgagtgtaa
     2341 tatactattt taagaccata catgataaat tgagttttgt tacccaaaga tggttaggtg
     2401 attacaaagc tcgtatagaa ctattatttc tacttcttat cctttgttgg attgtactca
     2461 tgaaggtatt agttaaagat tttttattat tttttataat tgttgacgca agcacgttat
     2521 tttgtctagt ggtaatttct tgcatctttt attatttaga aaactccaaa caaaattttg
     2581 actatgaaaa tagaagactg aactatttta tgaaatcaga ggaaaacatg agagtggagt
     2641 tctcaaatta tttgcatgat gatgttttac aaaatatcat agcgataaaa aacttgcttt
     2701 ctctagaaaa tagtaatata acacatggtt ttattgttaa tgagttgaat gatttagttt
     2761 ctggtattag agatgaaatg gatacttacc acccaatagt tcccgctaat caaacaatga
     2821 aagaaaacat acagtctctt tttgatgata ttgttaaaag tagaaaaagt aataccctat
     2881 tgtattttaa ctgttcagat aatatggtag tgccatctcc atatggagat attgtttata
     2941 ggtttataaa agagctaata aacaatgcta taaaatatgg agatggaaaa gacattcgtt
     3001 tatctttaac gattcaatct gatattatta tcattgagga gagcaatcaa gtagtggaaa
     3061 aagtacactc tataaattat ggtagaggat tgaaatcatt tcaagaaaca ctagcagctt
     3121 ttgatggaga tctagaacta caaatggata ctaaacaatt tactatcaga atattacttc
     3181 ccatagattg gaaattgtgt tatgaagatt ttattaattg atgaccacag actatttgca
     3241 aagagtatcc aactgttgtt ccaacagtat gatgaagtag atgtcataga tacgattact
     3301 tctcatttta acgatgtaac gattgatttg tctaagtacg atattatatt gcttgatatt
     3361 aatttaacaa atatttctaa agaaaatgga ttggagatag caaaagaact catacagtct
     3421 actcctcatt tgaaagttgt tatgttgaca ggatatgtta aatcaatcta tagagagagg
     3481 gcaaaaaaag taggagcata cggttttgta gataaaaata tagaccctaa acaactcatt
     3541 tctatcttaa aaaaagtgga ttctggaaaa aagtattttg aacaaatcga atctcaggat
     3601 tatgttgaat ctttaactga ccaggaaata gctatcttaa atttgagtaa gaaaggattc
     3661 tctataaaag aaatagagga aacgttacaa attagtagga gaacagtatt taatcatttg
     3721 acccacatct actcaaagct tttggtaaat aataagcaag aggctatcta caaagccgaa
     3781 caattagggt attttatgga tttctgagtt gcagataatc aaacgacata agttttactt
     3841 gtgtcgttgc tagggatttc ctgttaaata cccagattta aactcattgt ttttgagttc
     3901 tttttgattg aaattgattg agataacgct tttataaaaa gtagggcaat gcctgatatg
     3961 aaaagctttt taaatttagt caaacaaaag ttgtttaaac caggtctaaa aaaactcgta
     4021 aagcttcaca actcccagaa cgttaatata tgcttatata tcaacgattg gaactacttt
     4081 gtggttcgca ccatggtttt tgtggaagga tcaaaagttg tcctgaaaat ttctcttaac
     4141 cgtgtttaag ctttctaaac gtttgagaaa tcattgtaac ttcaaataac tattttaaat
     4201 aaaacaaaga aacggacaaa gttagatgag atgattctat tttgatttat aggtgaagaa
     4261 ggagaatctt gtttgataag tactcaataa aggttcacta ctcaatttta aataaaacgc
     4321 cacagtagta atcatctact gtggtgtttt ttggtctttt agtttctaaa agtatccaat
     4381 tcgtcttgtg cttctttggt tgttccgact agttgtttca tgagttgatc tagtttggca
     4441 tttgttttgg caatttcttg atcaatgtca ctgagctgtt tagctaattc tggcagtggt
     4501 ttgacgggga cttcctcaaa ggtatcgaca tagcgtggga tatttaagtt atagtcattt
     4561 tcaatgattt catcaaatga ggctaaatat gaaaacttat cagaattatc acgactctta
     4621 taggcattaa ggaccttttt gatatggcta tctgtcattg tgttttgatt tttgccttta
     4681 tcaaactctt ttgaagcatc gataaagaag acatctttgt tggttctgtt cttctttaat
     4741 atgataatag tcgtagggat gcttgtatta taaaagatat ttgatgggag tccgataatg
     4801 gtatcgatag ccccttgttc gagtagtttt tggcgaatct tgccttctgc agcaccacgg
     4861 aaaaggacac cgtgtggtaa gacaatcgcc atagttcctg tattttttaa atgatagaaa
     4921 ccatgaagta aaaaggcaaa gtcagctttt gattttggtg ctaatacacc ataacttgaa
     4981 aaccgtggat ctgttaagaa accagcagtc gctgaccatt tcaaagaata aggtgggttc
     5041 atcaacaccc catcaaagtt ggttggttca tctgttggcc agtctgcatc caaggtatca
     5101 gcgttactta agtgttggtt ttcgatggca acgccatgaa gcatcatgtt catacgagcc
     5161 aagttataag tagaagtatt gatttcttga ccatagtaag aaacggtatc ggattgatga
     5221 ctatatttct tagcatttaa aaggagtgat ccagatccca tagcagggtc atagagggtc
     5281 attccttttt gatcttcacg acctaaaaag acaatctgag tcattaagtg agatacagct
     5341 tgtggggtat agaactcacc tgcttttttt cctgactcac tggcaaattc accaatcaag
     5401 tactcataag catcacctaa agtatcccca tctactgcct caaagtcaat ttcatttaat
     5461 gttttcatga cattagaaat ggtttgattt tgtttttgag gagtagagcc taatttttta
     5521 gagtagaggt caatatcttc aaataagttt tcaaagtctt caccactttg ttcaatatcg
     5581 cgaaaacctt gagctaatga ttctaattgg aaagtattgt gataaacatc ttggatgagt
     5641 ttttcaaagg tcagtgtcgg ttcgataaag taacctaaat caccagtaac aacagaaatg
     5701 aggtcatctt ttaggccttg atcttgataa gcatcttcaa agattttttg agcatctgta
     5761 aaagtattaa agtgttcttc taaattatca caaacagcta tgagtaattt atcagataag
     5821 tgcttgtaaa agatgagtcc aagaagatag tttttatagt cattggcatc catttgacca
     5881 cgtaattggt cggccgaatg ccatagtgct tgacggagtg aagttgtttt ctctgccatg
     5941 tgagtccttt cttatacgaa taaacgattg agtaatgttt gtttgagtgc tttgagttct
     6001 gttagttttt cttcagattg agcaatttgt tggtctaaag tttggaagaa attaccaatg
     6061 gcttcttgtt cttttaatgt aggtatattt atctttaatt gttcaacaga tgaataattt
     6121 acatagattt gagtgccacc ttgagcaatt ttaatgatac cattacgaaa ttcaccattt
     6181 aaata
//
LOCUS       DAUGUF010000056         5685 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUGUF010000056 DAUGUF010000000
VERSION     DAUGUF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5685
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.056"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            49..1338
                     /locus_tag="VIB71_001611"
     CDS             49..1338
                     /locus_tag="VIB71_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8823331.1"
                     /translation="MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTV
                     GFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQ
                     TSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
                     LQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLA
                     IQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLT
                     YRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAM
                     SNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKET
                     YFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            1388..2413
                     /locus_tag="VIB71_001612"
     CDS             1388..2413
                     /locus_tag="VIB71_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8823332.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIVILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2427..2969
                     /gene="pgsA"
                     /locus_tag="VIB71_001613"
     CDS             2427..2969
                     /gene="pgsA"
                     /locus_tag="VIB71_001613"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEQ8823333.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2971..3810
                     /locus_tag="VIB71_001614"
     CDS             2971..3810
                     /locus_tag="VIB71_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8823334.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3786..4628
                     /locus_tag="VIB71_001615"
     CDS             3786..4628
                     /locus_tag="VIB71_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ8823335.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREV
                     LKHG"
     gene            4621..5421
                     /locus_tag="VIB71_001616"
     CDS             4621..5421
                     /locus_tag="VIB71_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ8823336.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         1858 a          900 c         1048 g         1879 t
ORIGIN      
        1 ctaatctttt aaagcttcaa actgtctatt ttttagaagg aatataaaat gacaaaatta
       61 gtaaagataa actatcctaa tattgacgaa gacctttact atgtaaaatt agaaaatggt
      121 ttaactgttt attttataaa aaaaataggg tttttagaaa aaacagctat gttgacagta
      181 ggtttcggtt ctcttgacaa taagttgaca gtcgatgacg aatcacgaga tgctccagca
      241 ggtattgcac actttttaga acataaactc tttgaagatg aatcaggtgg agatatttca
      301 ttaaagttta cacagctagg agcagagaca aatgccttta caactttcaa ccaaacgagt
      361 ttcttctttt caacagctag taaatttcag gaaaatttgg aactccttca atattttgtt
      421 ctttctgcta atataacaga tgaatctgtt agtagagaaa aaaaaataat cgggcaagaa
      481 attgatatgt atcaagatga tgctgactac cgtgcatata gtggaatcct tcagaactta
      541 tttccaaaaa caagtttagc taatgatatt gctggctcaa aagcatccat tcaaaagatc
      601 acgaaaatat tattggaaac gcatcatact tatttttacc aacctactaa tatgagtcta
      661 ttcattgtcg gtgatattga tattgacgaa acttttttag ctattcaaag gtttcaaacc
      721 acattatcct atccagatag aaaaagggta actgttgatc ctttacacta ctatcctgtc
      781 attaaatcat cttctgttga catggatgtt actactgcca agctggttgt tggttttcga
      841 gggtatctga ccttaactca gcattcacta ttaacgtatc gtattgcctt gaagctattt
      901 ttatcaatgc ttataggttg gacttctaaa atctatcata cgctatatga agatggtaaa
      961 atagacgatt catttgatgt ggatgttgaa attcatcata attttcaatt tgtattaata
     1021 tcacttgata caccagagcc tatcgcaatg tctaactata tccgtcaaaa attagctact
     1081 ataaagatat caaaagagtt tacaaatgag cacttaaatc tattaaaaaa agaaatgtat
     1141 ggtgacttta ttcagagttt agactctata gaacatttaa cccatcagtt cagtctatac
     1201 ctgtctgatt ctgataaaga aacatatttt gatattccaa aaattataga aagactcact
     1261 ctaaaagatg ttgttacaat tggaaaagca ttttttgaaa aagctgatgc ttcagacttc
     1321 acagtcttcc caaaatagat gaaaatctgt tataataggg ttactatatt atttttgagg
     1381 tacctgtatg agtgaaaaaa gtcttggtga agtgttaaga gaatcgcgtg ttggaaaaaa
     1441 tatcacacta gatgatatag aattgaagac agggatttct tcccattact tgctggcaat
     1501 ggaattggat cagtttaaaa ttattccgga agaaaaattt gatcaatttt taaaagaata
     1561 tgctgacatt gttgagttag atttcaatac tttaaaaaga cgataccgtt atcaagttaa
     1621 ttccaaaaaa gacagtgata taaaatctgt aactgagatt gttgaagaga agttaagtaa
     1681 gaaacgatta caagagaagt tgttatcaca tcagagcatg gggtatggtc aaccgttaga
     1741 agtttctaaa aacaaagaaa ccttagttat ccctgtaaag actgttggtt tagatagcaa
     1801 atcgccacta aaaacgatat cgcctgttag ccaatttaaa tcagataaca ggttaattcc
     1861 taaaaaaaat gtgtcacgta tgaggcgaaa tagcactgac agtcgttcta aaacgtcact
     1921 atttcccata gttatattag gaacgattgc ttttgcaatt atcagtgtta tcattttagg
     1981 tgtttggcaa caattcgaaa agagtcaaag agctaaagaa gctgaagttg ctttgcttaa
     2041 agcctctgag cagtctacta acggtttaaa aaataattca aatgatcgca aaactcaagt
     2101 cacaactgag gggtcgggta attatttaat agcgactgtt actaaatcta aagagaccgt
     2161 tgatatcagt gtgtctttaa ccgaggcaca aagtagttgg atttctctaa caaattcaga
     2221 aattggtgaa ggtggtataa cattgactca agactcgcca acttatacag cgactttacc
     2281 tgcagaaata acagaatcat tgttgacact tggtgtgaca aaaggtgtat ctgtaacaat
     2341 tgatggacaa cctgttgatc tatcaccttt aacaagtact gacttaagtt atatcacgtt
     2401 taagatccaa taattaaggt agactaatga taaaaaaaga aaatattcct aatctattaa
     2461 ctcttgttcg aatcgcaatg attcctttct ttctttttat tacttcctca tctaataagg
     2521 tggggtggca tatttttgca gctgtgattt ttgcaattgc cagttttacc gattatctag
     2581 atgggtatct tgcgcgtaag tggcatgtag ccagtaattt tggaaagttt gccgatcctc
     2641 tagcagataa gatgcttgtc atgagtgcct ttatcatgtt agttggactt ggcttagttc
     2701 ctgcgtgggt gtcagctgtt attatttgcc gagaattggc agtaactggt cttcgattac
     2761 tacttgttga aaccggagga aaggtccttg cagctgctat gccgggaaaa atcaaaacag
     2821 cgacacaaat gttgtctatt attttattac tttgccattg gatattccta ggaaacgtct
     2881 tactctatat tgctcttttt ttcactattt attctggata tgattatttt aaaggagcaa
     2941 gctttctttt taaggatacg tttaaataac atgtcagcta ttattgaact taaaaaagtt
     3001 acatttaatt accataaaga ccaagaaaaa ccaacattag atggcgtatc gtttcatgtg
     3061 aaacaaggtg agtggctgtc tatcattggc cataatggat ctggtaaatc aacgactatt
     3121 cggttaattg atggattatt ggaaccagaa tcagggtcta ttattgttga tggagatcta
     3181 ctaaccataa ctaatgtttg ggaaattcgt cataaaattg gtatggtctt tcaaaaccct
     3241 gataatcagt ttgttggagc aactgttgaa gatgatgttg cttttgggct tgaaaataaa
     3301 ggtattgcac atgaagatat aaaagagagg gttaatcatg ctttagagtt agtcggcatg
     3361 cagaacttta aagaaaaaga accagcccgt ttatctggtg gccaaaaaca gcgcgtagct
     3421 attgcaggtg cagttgctat gaagcctaaa attattattt tagatgaagc tactagtatg
     3481 cttgacccta aaggacgatt agagttaatc aaaactataa aaaacatccg tgacgactac
     3541 cagctgactg ttatttccat tactcatgac ttagatgaag ttgctcttag tgatagagtt
     3601 ttagtgatga aagatggtca agtggaatca acatcaacac cagaacaatt atttgcaaga
     3661 ggggatgaac tactccaatt aggtcttgat atccctttta caacatctgt tgtacagatg
     3721 cttcaagaag aaggttatcc tgttgactat ggatatctca cagaaaagga attagaaaat
     3781 cagttatgtc aattaatctc caaaatgtaa gttatactta tcaagcaggg actccttttg
     3841 aagggcgtgc cctttttaac attaatttag atattttaga tggttcttat acggctttta
     3901 tcggacatac tggatccggg aaatcgacca ttatgcaatt gctaaatggt ttacacgttc
     3961 cgacaacggg aattgtcagc gtagataaac aagatataac gaatcactct aaaaataaag
     4021 agattaaatc tattcgaaaa catgtaggat tagtttttca atttccagaa agtcaactat
     4081 ttgaagagac agttttgaaa gatgttgctt ttggccctca aaattttggg gtctctccgg
     4141 aggaagcaga agctttagcg cgtgaaaaac tagctcttgt tgggatttca gaaaatcttt
     4201 ttgaaaagaa tccatttgaa ctctcagggg gtcaaatgcg tcgtgttgct attgcgggta
     4261 tccttgctat gcagccaaag gttttagttt tagatgaacc gactgctggt cttgatccta
     4321 aagggcgtaa agaattaatg actattttta aaaagttaca ccaatctggc atgactattg
     4381 ttttagtaac ccatctgatg gatgatgtgg ccaattacgc agattttgta tatgttcttg
     4441 acaaaggtaa aattatttta tcaggaaaac ccaaaacaat ttttcaacaa gtcagtttgc
     4501 ttgagaaaaa acagttagga gttcctaagg tgactaaact tgctcaaagg cttgttgata
     4561 gaggaatacc tatctcttct ttgcctatta ccttagagga gctaagagag gtactaaaac
     4621 atggataagc tgattcttgg tcgttatatt cccggagatt ctctcattca tcgtcttgac
     4681 ccaagaagta aattattagc gatgattatt tatattgtca ttatcttttg ggctaacaat
     4741 gttgtgacaa atttgttgat gttgactttt actttagcag ttgttttttt gtcaaaaatc
     4801 aagttgtctt tctttttaaa tggggttaaa ccaatgattg gtattatcct cttcacgact
     4861 ttatttcaga tgtttttctc acaaggagga aaagtaattt ttagttggtg gttcattagc
     4921 ataactgatt taggattgag ccaagctatt ttaattttta tgcgtttcgt tctaattatt
     4981 ttcttttcaa cgctgttaac gttgacgaca acacctttaa gcctatctga tgcagttgaa
     5041 tcattattaa aacctttaac aagatttaaa gttccagctc acgagatcgg actaatgctt
     5101 tctttaagtt tacgttttgt gcctacttta atggatgata ccacgcgtat tatgaatgca
     5161 caaagggccc gtggagttga ttttggagag ggaaatttaa ttcaaaaagt taaatccatt
     5221 attcctattt taatccctct tttcgcttca agctttaaaa gagccgacgc attagctatt
     5281 gctatggaag ctagaggtta tcagggagga gaagggcgaa ctaaatatcg tcaattagac
     5341 tggcagctaa aagatagttt agctattgga atagtttctt tattgggttt gctacttttt
     5401 ttcttgaaaa cctctttgta atatttttta gcataaaact tttctttatt agtaagaagt
     5461 gaattgtacc tcaaaagtta gatacaacat ctaatcattg aggtactttt cttcatttga
     5521 ggaattgaaa accgctatct caactatatt aatcatccca acaataacaa atcgaacgaa
     5581 atctaaaagg actgagtcct gttcaataca gaactaaatt cttagtttaa tgatattatc
     5641 ccgcttttta atgttgctaa gaagaagagt tttatgattt tttac
//
LOCUS       DAUGUF010000057         5598 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUGUF010000057 DAUGUF010000000
VERSION     DAUGUF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5598
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.057"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(264..1406)
                     /locus_tag="VIB71_001617"
     CDS             complement(264..1406)
                     /locus_tag="VIB71_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEQ8823337.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFCQTTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
     gene            1687..4665
                     /locus_tag="VIB71_001618"
     CDS             1687..4665
                     /locus_tag="VIB71_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEQ8823338.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIF
                     DVNETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRYLTNTFRNSRWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLNSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIVYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQSDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            4678..>5598
                     /locus_tag="VIB71_001619"
     CDS             4678..>5598
                     /locus_tag="VIB71_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ8823339.1"
                     /translation="MTKSKQPQYRFDGFKGEWEEKELGDIVQITMGQSPSSQNYTTNP
                     SDYILVQGNADIKNGYIFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIGRG
                     VAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIPSLPEQEAIGE
                     LFQTVDQLIQLQDQKLATLKEQKQTFLRKMFPPQIQKVPEIRLQGFKGEWEEKKLGEV
                     STHRSGTAIEKYFDSEGEFKVISIGSYGTNNLYVDQNIRAVSNELTNSKLVASGELTM
                     VLNDKTANGAIIGRCLLITENNKYVVNQRTE"
BASE COUNT         1863 a         1086 c         1024 g         1625 t
ORIGIN      
        1 acgtctccta agagacaact tctttattct atcaggtttc tcatagcctg tcaactactt
       61 tttcatcttt tttcaataag tgtgttacag gaacctctct gacagcttta ttagtatacg
      121 atatctttac tgtcattgtc aactcttttt tacaaaatgt ttctgttttt catactatgc
      181 taatgagtta gctcgtgcgt ctccttcttc ataggttact tttaaccgcc agatgaatgc
      241 tacacaatcg aaaatagatg agtttactta ttaaactgag ctatcaatag cataaggtta
      301 gctgctaata ttttgatatt agaaagtgtt gttgttttat ctatcgctgc ttctaaggaa
      361 attggctgct gttgtattga aaaaacagcc aaaaagtctt ctgctgctag tcctgtctca
      421 atctttacag aaccacatag agcaatcgtt ggaacttgat attttttagc cattcttgca
      481 atcgcaacag gtaccttgcc agattgtgat tgtgtatcca ggcatccttc tccagtaata
      541 actaaatcac aagactgaag ggaattatcc agatttagta gctctgcaat cctgctaaaa
      601 ccactagtta aggtgcctcc taataggaca atggcacctc ctaatcctcc agctgctcca
      661 cttcctggta ttgtctgtaa atcaatggtt gtttggcaaa aaactttttt agcaaagtta
      721 cttgcaattt gatcagtttc ttcaatttga ctaagactcc cacctttttg agggccaaag
      781 accgcagcaa atccttgagg gccatgatat ggattggtca catcagtcag ccctaatagc
      841 gtaacaggtg atgctaaagt atcaagataa gatcttcctg tcatgaaatc atagtttaaa
      901 ctttccaaaa accctttgcc accatcagaa gtgcctgttc ctcctagcat gatttcgatt
      961 tgagtagctc ctttttgaat ggcatcttta actgccaaac ccaaaccata ggaagtggct
     1021 tgtgcatagg ttactgaatt gggggtgatc ttatcaatac caataatact cgcagattca
     1081 ataaaagctt gctttgcgtg acgataataa gcgactttaa tcgggcgtct taatagatca
     1141 atggttttta cttgatgcca cctccccgcc acggtttgtg agagggctgc taaacttcct
     1201 tctcctccat cagcgatagc tcttgtttca ataactaact gcttatcgac agaaagaagg
     1261 gcttgagcta cactagtgtt aagttctgga gacgttaccg atcccttaaa agaatctatg
     1321 gctaccaaaa ttttcatatc ttcaataaat tccttttctg tatattgtag cagattatcg
     1381 tcctttaaaa ccctattaat agtcaagcta gatctgtctt aagtttttta tctattttga
     1441 gaactcgacc tttttactaa tgttgtctta ttactttctt caccttaaat tattgtcaag
     1501 caaactcaaa aatacaagaa ctttctcgat tgcatttaca tagtcatagc tttgtttagt
     1561 tgctaggatc ttaagcattc aactaatcaa aaaaagactg tttggaaggt ttcaatagct
     1621 ttgccattct aaaaaggatc cgccaatgat ataatattac tatatcatgt cgaatgggga
     1681 ttaaaaatgg gaaatcaaac taaaacggaa cttgaacttg aaaaagagtt gatccatctc
     1741 ttagaaacag gtgaaagtca atggacatat cgtaaagaat taaaaactga agatgcttta
     1801 tgggataatt tctttaagat cttagcgcaa aataacacgc aatatctgaa cgaggagcct
     1861 ttaacagcta gtgaaaaaga gcagattaag aatcaactta actttgtcaa ttactatgaa
     1921 gcggctaaat ggttagctgg tgaaaacggc attgctaaag tacaagtgca acgcgaagat
     1981 gcaaaactag gaacgattcg tttagaagtc gttaaagcag acaatgtggc tggtggaact
     2041 tctgtttatg agattgccaa tcaagttgct ttctctggtt ctcgtgatag acgaggtgat
     2101 gtgacacttc tcatcaatgg cttacctatg atccaaattg aattaaaatc tcagaatcat
     2161 caatgcattg aagcttttaa ccaagtcaaa aagtatgata aagaaggcca gtttagaggt
     2221 atcttttcaa ccttacaaat gtttgtggtc tcaaataaaa cagatacaag gtatatcgct
     2281 gcagctaaag aaaataaatt aaaccctaac ttcttgaccc aatgggtaga tcaaaacaac
     2341 aaaccacaaa aagatctctt tgcctttgcc aaagaagtcc tatctatccc tcgtgctcac
     2401 caaatggtca tgacttactc tgtcattgat gatgataaaa aagcactaat tctccttcgt
     2461 ccttatcaga ttcatgcaat cgaagccgtc gctgaagcga gtcgtcaccg caagtctggc
     2521 tatatctggc acacaacagg ttctggaaaa accttaactt cctataaagt ggctcgcaat
     2581 atccttcaaa taccggccgt tgaaaaatcc atctttgtca ttgaccgaaa ggatttagat
     2641 aatcagaccg cttctgcttt tcaatcctat gcgcaaaatg atatctttga tgtcaatgag
     2701 acagaagata cgagacaact catcaaaaat ttagaatcca gtgatcgtcg tgttgtggtc
     2761 accaccattc aaaaactcaa tgccatgatc agtcagatgg aaagttatga cactccaaaa
     2821 ttcaagaaac taaaagagcg tcttgcacac ttaaatgttg tctttgttgt ggacgaatgc
     2881 caccgtgctg tcacaccgga acgtcaacgt tatctcacga atacttttcg taacagtcgc
     2941 tggtatggct ttaccggcac tcctatcttt gtggaaaata agcgtgctca attaggtgat
     3001 ttagcccaaa caacggaaca gcaatacggc aaatgtctcc atcaatacac cgttaaagaa
     3061 gccattcatg ataaagcggt tctaggcttt caagttgagt ataagacaac cattcctgat
     3121 atgcctgaag acagtattcc ggaagaagct tatgatcatg aagaacatat gttagctgtc
     3181 ttaaatagta tcattaatca atcacgtaag aagcttggct ttaataatgg gattggtcag
     3241 acattcgaag gcttattaac cgttaagagt attgctcgtg cccaagccta ttatgatctg
     3301 attcagaaag ttaaagctgg tgaaacggat ttagtcattt ctaagaaggt caaagaaaaa
     3361 ctaccagact ttccaaaggt agctattact tattctatca ctgaaaatga caatgcgtct
     3421 atcagccgac aagataaaat gaccaaaaat ctagaagact ataatcacct ctttggcact
     3481 aactttacca tcgataactt acaaggctat aacagagatt taaatgatcg cttagcccgt
     3541 aaaaaagata aattcaaaga ccgtcatgaa caattagacc tcgtgattgt ggttgaccgt
     3601 ctcttaacag gttttgatgc gccttgttta tcaacgatct ttattgatcg ccagcctatg
     3661 aaacctcagc acattattca agctttctca cgaaccaacc gtatctttga aagtagaaaa
     3721 cattacggtc aggttgtgac tttccaaaca ccacttcgtt ttaaagaagc tgttgacaaa
     3781 gcgcttagcc tctactctaa tgggggtgaa aacgacgttt tggccccttc ttgggaagaa
     3841 gaaaaagcaa gattctttga aaaagtaaca gtattaaaaa atatagttcc tgatccagac
     3901 gctttcccaa ctattgagag cgcacagaca gcttttctca aacaatacgc caaagccttt
     3961 caagcgtttg ataaactctt tgcatctgta caggtctata gtgactttaa tgaaacactg
     4021 ttgagtgagg ttgggttatc agatgaagtg attgatactt ataaaggcac ttaccaaaat
     4081 gtcattgcag aaatacgaaa gcgaagagaa gatgacgaag ccatcccaga gatcaatatc
     4141 gactatgagc tagaaagtgt tcagatggat gatatcaact atcactatat cttgacctta
     4201 attcaagcct ttgtcgatca agaacaagaa gctcttcaag aaaggctcaa tgacaatcct
     4261 atggatcaat acatccaaga tttggcaaaa tcaaaccctg ctatggctga ctcactagct
     4321 gagttatggc aagatatcca aaaagaaccc aaagcctatg aagggaaaag cattgtttat
     4381 gagttagata acctcattgg tgataagatc caaagggcca tcaaacactt tgcggaccaa
     4441 tggaaagcag atcctgacaa attagccttt gtggcgacta attatcatag tgctaactct
     4501 accaaacaag tgggcatgtc aaccttaaaa gaatccctag actaccaagc ctataaagaa
     4561 aaacaaagtg attctgccat gaataaactc aaatacaaga gccaatttga acgggagtta
     4621 gttcaattca ttagagatca aatccaaccc ttaaaagggc actaggaaag gaaagagatg
     4681 acaaaatcta aacagcctca atatcgcttt gacggtttta aaggggagtg ggaagaaaaa
     4741 gaactagggg atattgttca aattacaatg ggccaatctc catcaagtca aaattatact
     4801 acaaaccctt ctgattatat tctagtacaa ggaaatgccg atataaaaaa tggatatatt
     4861 tttccgcgtg tctggacaac acaaattaca aaacaagctg acaaaggtga tattattctt
     4921 agtgttaggg ctccagttgg tgatgttgga aagacaaatt atcatgttat tattgggcgt
     4981 ggagttgctg ctataaaagg taatgaattt atctttcaaa tattaaaata cttgaaagaa
     5041 attggttatt ggaaaagaat tagtacaggt tcaacttttg atagcattag ctctagtgat
     5101 atcaaatatg ctaaaattca aattccctcc ctccctgaac aagaagccat tggcgaactt
     5161 ttccaaacgg ttgatcaatt gattcagttg caggatcaaa agctagcaac ccttaaagaa
     5221 caaaagcaaa ccttcctcag aaagatgttc ccacctcaaa tacaaaaagt ccctgaaatc
     5281 cgtttacaag gttttaaagg agagtgggaa gagaagaaat tgggggaagt atctactcat
     5341 agaagtggaa cggcaattga aaaatatttt gattcggaag gtgaatttaa agtcatttca
     5401 ataggtagtt atggaactaa taacctctat gtagaccaaa atattagagc agtctcaaat
     5461 gagcttacta attctaaatt agttgcctcc ggtgaattaa caatggtact caatgataag
     5521 acagcgaatg gggcaataat cggaagatgt ctacttatta cagaaaataa taaatatgtt
     5581 gttaatcaaa gaacagaa
//
LOCUS       DAUGUF010000058         5079 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUGUF010000058 DAUGUF010000000
VERSION     DAUGUF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5079
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.058"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..914
                     /locus_tag="VIB71_001620"
     CDS             <1..914
                     /locus_tag="VIB71_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ8823340.1"
                     /translation="EENYSQEIPTRIKNLRKKHNITQSELGNAGQVSQVESGKRPITS
                     SMLVYLNALTASSYTYIVFGELDEFIENLFHYFFSSILYRDLEAVDENLYSFMSDDLI
                     SIQSSCLSIAKTFANFNIQRKRFMISTETEMDTFHKKDDIDVWVGGKSYNPARSFRNN
                     PINELTVIDFEEMADILLLMLRDNLIRSFEINVCNTLFELDKNGEPTTFNLDKIDSII
                     NKWWSENVSTEIIPNLIKKLRENPLFNIGFMVNDILERMYKEDIPKSYLTSVPLVISK
                     KARSTLSIKSNGSQKIDKSKFAQILSL"
     gene            980..1732
                     /locus_tag="VIB71_001621"
     CDS             980..1732
                     /locus_tag="VIB71_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ8823341.1"
                     /translation="MAIPDLDKFSSNLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            1729..2331
                     /locus_tag="VIB71_001622"
     CDS             1729..2331
                     /locus_tag="VIB71_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823342.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(2711..2992)
                     /locus_tag="VIB71_001623"
     CDS             complement(2711..2992)
                     /locus_tag="VIB71_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ8823343.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRSALRIERFKKTYDVQTYR"
     gene            complement(2999..3043)
                     /locus_tag="VIB71_001624"
                     /pseudo
     CDS             complement(2999..3043)
                     /locus_tag="VIB71_001624"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3446..4288
                     /locus_tag="VIB71_001625"
     CDS             3446..4288
                     /locus_tag="VIB71_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEQ8823344.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVIVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKVDWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAVVLFALGIWLGLWMSQLE
                     EKYK"
     gene            complement(4335..4976)
                     /locus_tag="VIB71_001626"
     CDS             complement(4335..4976)
                     /locus_tag="VIB71_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEQ8823345.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWESIQPNEEVDKVFTVPLRQLLVTDPVYYHLEATPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPLDIEKSKGR"
BASE COUNT         1580 a          950 c          846 g         1703 t
ORIGIN      
        1 ttgaagaaaa ttattcacaa gaaataccta ctcgtatcaa aaatttaaga aaaaaacaca
       61 atattacaca aagcgaacta ggcaatgcag gtcaagttag tcaagttgaa agtggtaagc
      121 gaccaattac gagttcgatg ttagtttatt taaatgctct aaccgcttcg agctatacgt
      181 atatcgtttt tggagagtta gatgagttta ttgagaatct gtttcattat tttttcagtt
      241 ctattttata tagagattta gaggctgtag atgaaaacct atattctttc atgagtgatg
      301 atttaatttc aatccaatca agttgtctaa gtattgccaa gacatttgca aatttcaata
      361 ttcaaagaaa aagatttatg atttctactg aaactgaaat ggatactttt cacaagaaag
      421 atgacattga cgtatgggtt ggtggaaaaa gttataaccc cgctaggagt tttaggaata
      481 atccaataaa tgaattaact gttattgatt ttgaagaaat ggctgatatt cttttgttga
      541 tgttgagaga taatctaatt aggtcgtttg aaattaatgt ctgcaacaca ctgttcgaat
      601 tagataaaaa tggtgaaccg acaacattta atctagataa aattgactca ataatcaata
      661 agtggtggtc tgagaatgtc tcaacagaga taatacccaa cctcataaaa aaacttagag
      721 aaaatccctt gtttaatatc ggatttatgg taaatgatat attagaacga atgtataaag
      781 aggacatacc aaagtcttac cttacttctg ttccattagt tatttccaaa aaagcaaggt
      841 caactttatc gattaagtca aacggaagtc aaaaaataga taaatcaaaa tttgcacaga
      901 ttttgtccct ttagagacgg atgacttaca cattcaacgt ggattattct tcccttggag
      961 aaaggggatt tcagaacgct tggcgattcc tgatttagat aaattttcat ctaacttaca
     1021 acaggggaaa attcctgtca taaagcactt cgaactcaat ttagataagg ggagtcactg
     1081 ggctattgct ggaaattcag gttctgggaa accgtacgct ctcacttact tcttgagtgt
     1141 cctgaaacct atgtccggcc taattatcat tgacccaaaa ttcgataccc ctagccaatg
     1201 ggcaagagaa aataaaattg ccgttatcca cccagtagaa aaccattcaa aatctgattt
     1261 cgtttcacaa gtcaatgaac aattaaacca gtgtgcaact ctcattcaga aacgacaagc
     1321 tatcttgtat gataatccca atcatcaatt tacccatcta actattgtta ttgatgaagt
     1381 cctcgctcta tcagagggag tcaataagaa tatcaaagaa gcttttttct ccctactatc
     1441 acagattgcc ttgttgggac atgctactaa aatccatcta ttcttgggaa gccagcgttt
     1501 tgaccataac actattccca tttcagtgag ggaacagcta aacgtattat tgcaaattgg
     1561 aaatatcaat cagaaaacca ctcaattctt atttccagac ctagatccag aggggattgt
     1621 cattccaaca ggacacggaa caggtatcat tcaagttgtc gataatgaac actcctatca
     1681 agttctaccc ttactctgtc caacctacta tactaagcga ggtatcctat gaccactaaa
     1741 acctacttca tgagaagctt caatctcata ttatacttac tgcttattgc tccaatctgc
     1801 tatgtgttcg gttggctgtt caatcttgtt tcagttcaat tatctaccgt cacatttgtc
     1861 aatctggata cggttaaaaa cgttactgat accattagtt ctgtatgtta tggattcgct
     1921 cttatttctt tacttctagc cttattatct ggattaaaga tgatacaacg cttgaataca
     1981 gatagccttg ggaactactg ccaatctatt tatcgcacct ttctattaag acacttcctt
     2041 ttccagcgtg aacgagtaca gaaggtaagc aactttgaac accagaccgt taccactatc
     2101 aatccaatcc ataacgggtt taaccgagct gtacgtaagt gtatcgtaga tatacgaaaa
     2161 gatgccatta ctgtatttct aaaagttcct agagaccaac aggggcaaaa aatcctaaag
     2221 gatacgggag tacaactgaa agaagagatt gtcatccaac acacagacta ttatttctct
     2281 tctcctgttc gagttcgtaa ccaattgtgg tttattggtc aaaagcgtta attccttggg
     2341 gctgtgggta tttatttatc ttgaaaagat tgctgaacta acgcaataac tactctacca
     2401 ttcactctac cttttattaa gcaactatca ataaatattg atacaataag gtttataaca
     2461 gctaaaatag aaaatactta acctttacag aagtaaaata attgagatga gaaaagccta
     2521 tgaaatgaac gtttcaaagg cttttttcgt gtttaaaaaa acaaatgaaa aaacaaaata
     2581 gagagtaggg ttattaacac tgtcaatcct gtgtacgcaa taacaatcca tgctttttga
     2641 taaggatatt ttgcttttct ttaatcttat caatctgatc taagctctca ccctttgcta
     2701 tagcttcaag ttatcggtaa gtctgaacat catatgtctt tttaaatcgc tcaattctta
     2761 aggcgctacg catgattatc aaccataaga tagcaaccgg accatatccc caccaaccta
     2821 accaagacat tataggataa atactgatag caattaggag tgtcccaaat aacataatat
     2881 gcgtattcct atcacattgt ttaatctcct catccttaat aattaaagtc atttttggga
     2941 tatcttctgc tattagttgc tctaaaggaa cctgtaagga cttacttaac atcaaaagat
     3001 tttgcaggtc tggatagctt ttaccgtttt cccagtttga gatagtcttc ttgaaacata
     3061 catcatttca gcaagctctt cttgtgacat ctgtaatttt tttcaataat aaggtaactg
     3121 gtttttaaag tccataataa atctcctttt taatagctac tataatcctt cttcaataag
     3181 tttactatca aaagtctttg acctaagctt tttttcgttt atctttttga taattatcgt
     3241 aaggtttaca gtctttgtaa aatttattta caactttgac aatcaaactt gacttgatca
     3301 caaagacatg gtgtttaagg aaaatatctt caaaattgaa tgtattattt attaggaaca
     3361 attattttag tagggatatg cagctttgtg tcagcaattc tttaaattta tgatacaata
     3421 aaatcattct tttcaggagg caacaatggt ttcatttatt tcaagagttt ttaaaggcat
     3481 gattattgca ctaggtttta ttttacctgg tgtatccggt ggtgttctcg cagccatttt
     3541 aggaatctat gagcgaatga tttccttttt agctcatatg agggataact ttattgaaaa
     3601 tgtcttattt ttcttaccag taggaattgg tggtatttta ggtattgctc tcttttcttt
     3661 ccccgttgag tttttgctta agcactatca agttatcgtc ttatggggat ttgctggcgc
     3721 tattgtcggc actattccta gtctgattaa ggagtcaacc aagcagtctc aaagagacaa
     3781 agttgactgg ctatggctag tccttacctt tgttatttca ggactaggtc tttacttctt
     3841 aaatgactta atcggtacct taccagctaa ctttttaacc tttattttag caggtgcctt
     3901 aattgcttta ggagtactgg tccctggact aagcccgtca aatctcttac ttatcttagg
     3961 actctatggt cctatgttaa taggattcaa atctttggat ttattaggga ctttcttacc
     4021 tattgctatc ggaggagtcc tagccatctt ggctttttct aaaagtatgg attatgcttt
     4081 acagcaccat cattcaaaag tttaccactt tatcattggt attgtattat ccagcacgct
     4141 attaattctt attccaaata gtagtagtcc cgaatccatt tcctacagtc atgcaggtat
     4201 cttaacctgg cttatggccg ttgtgttatt tgctcttggt atttggctcg gactttggat
     4261 gagtcaatta gaagaaaaat acaaataacc tttacaggtt gttgacaaaa agttgacacc
     4321 aacaaactag tgctctatct ccccttagat ttttcaatat ctaaggggtt tttctttgca
     4381 attgattcat catttagaat atcggttaaa cacttagtaa actgggcagt cattccccat
     4441 atggtttctt ctagattttc gtaaaacgga atactacggt actcttgact aaattggtag
     4501 tatttcccat tacgaatacg gtcaaaagga aaatccgttg tctcaatagg agtggcttct
     4561 aaatgataat agacaggatc agtgacaagt agttgacgta aaggtactgt aaagaccttg
     4621 tcaacttctt cgttaggctg tatgctttcc cagtcatcaa cgactaattg accaacgaaa
     4681 caatgaatag ttctagaaga ctgtactaaa taatcaattt caccccatag ctggatctgg
     4741 gacgcatcaa cagtcaattc ctcaactgtt tctcggatag cagcttcttg aagtgtctcc
     4801 tgattttcta cttgtccccc tgggaaagaa acttcccccg gttgtgaaat atgctgactt
     4861 ctgacttcat ataagacatg ccagtcatca ttgacaagaa taagaggtaa aaatacggcg
     4921 taccgcttct cctctcctag tggttttgcc tgatactgtt ttaataaatc cttcatagcc
     4981 ttccctaatt tctctttctg ttaatcttat cttcatcata accaatcctg gctttttggt
     5041 caacttatta ctcctagtta gtgatttttg atatatata
//
LOCUS       DAUGUF010000059         4737 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUGUF010000059 DAUGUF010000000
VERSION     DAUGUF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4737
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.059"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(92..631)
                     /locus_tag="VIB71_001627"
     CDS             complement(92..631)
                     /locus_tag="VIB71_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEQ8823346.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(635..946)
                     /locus_tag="VIB71_001628"
     CDS             complement(635..946)
                     /locus_tag="VIB71_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823347.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(1164..2306)
                     /gene="tgt"
                     /locus_tag="VIB71_001629"
     CDS             complement(1164..2306)
                     /gene="tgt"
                     /locus_tag="VIB71_001629"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEQ8823348.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            2525..3388
                     /locus_tag="VIB71_001630"
     CDS             2525..3388
                     /locus_tag="VIB71_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEQ8823349.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGGSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            3585..>4737
                     /locus_tag="VIB71_001631"
     CDS             join(3585..3915,3915..>4737)
                     /locus_tag="VIB71_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ8823350.1"
                     /translation="MIRLIDRYGVTIVQKCKNHYYSPELKQKIINKVLIDGQSQKQTS
                     LDYALPTSSMLSRWIAQYKKNGYTILEKPRGRPSKMGRKRKKNLEEMTEVERLQKELE
                     YLRAENAVPKKAERIPLEGRSKAQRATEIIQALRNPFPLEMLLEILDLSRSTYYYQVK
                     RLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAA
                     RIRRKRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPEGKLYLLPVLDG
                     YNSEIIDFTLSRSPNLKQVQTMLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKG
                     ILPSTSRKGNSPDNGMMESFFGILKSEMFYGLETTYQSLDKLEEAITDYI"
BASE COUNT         1503 a          935 c          926 g         1373 t
ORIGIN      
        1 tcttcatgcg tttggcgtgc accaaaaaca ggtcctagca gataaatctg ccaagacctg
       61 ttcaacacaa cttaactatt tgatgattag attactgttt tgtattcaaa aaactatctt
      121 tgtatttaac agcgataatg gtcgcaatga ttgctttgat ggtatctcct ggaataaaga
      181 ccaagtttga caaaagcgat gtcacaagag acatgccagt gtaggctgcc aaccagatag
      241 cacccagaac atcaaccagt acaactcctg agattaaaag agctaggaat gccaatggcg
      301 tgctttttga gaaccagttg cggtaaagta atgaaaagac aataggcaca agaaggtagg
      361 caataacata gccagcagat ggccccatca atactggaat ggttgttcgt gagcctgaga
      421 aaacaggtaa gaaaaggcca atcactaaaa ataagaaaac agataaggtt ccttttttac
      481 cacccagcat caatccagcc aacatgacac ctaagttttg taaaacaata gggactggga
      541 taaagcctag cgggatagca ggaataaagc ctaaaataat aatcaaagtg gtcatcatag
      601 ccaccttaac aagttctttg gttgtaaaca tctgttacga ctcctttaaa aaatagatat
      661 ccttgtgcct atgacaggct ggattaaagg gactttgaca ataaggacag catccacaac
      721 catactcagc taggctcaag agctttcgac aatgcccaca aataacagga gatgtttctt
      781 gatgtcctgt tggcacaaag gcatgatctg ttaactggtc atggcaatgg taacaagcat
      841 aataagtctg acaaaaagca catttgagcc caacaatatc aagcggggta tgataatgta
      901 ggcaccgata ctcttggtca aggtcaattc caaaacagtc cgtcatatct catcctcttg
      961 taacagttta atcaaaagct tatgatttgt caactatatt tttacaaaag ggtaactgtt
     1021 ttctgaaaaa gaacacgtaa aacaagaact tccctttaaa gagtgaccta tcagttgaaa
     1081 gcaataggac atccgtctac acaaaaaaac ctgaaaccaa agacgataga tcgccctcag
     1141 ttccaggatc atagcatttt taattagaaa ttacggtttg atttattata accataccgt
     1201 tcaagaaaat cttggcggaa ttcaagtaag ttatcgtcca taatagcctg acgtactttt
     1261 ttcatcaagt taaccaagaa ataaaggttg tggtagcttg tcaaacgaat accaaaagtt
     1321 tcgtccgctt ttagcaagtg acgaatgtag gcacggctat agttttgaca agtgtagcag
     1381 tcacagtcat gatcaagtgg ggtaaaatct tcagcgaatt tggcattttt aatcacaaga
     1441 cgcccctcac tagtcatgca agttccgtta cgggcgatac gcgttggcaa gacacagtca
     1501 aacatatcta caccacgaat cacaccatca atcaagctat ctggtgctcc cactcccatc
     1561 aggtaacgag gtttattttc tggtaagagg ggagtcgtaa agtcaaggac ggcattcatt
     1621 tcttcatggc tctccccaac agctaaacca ccaatagaat aacctgggaa atccatagcc
     1681 accaaatctg ccgcagactg acgacgaagg tcctcaaatc cagctccttg tacaattcca
     1741 aataatcctt ggtcatgagg acgacgatgg gcttttaagc cacgttctgc ccaacggcta
     1801 gtacgttcaa tggatttttt cacgtaatca taaggttggt aaaattgcgg gcactcgtca
     1861 aaactcatca tgatgtctga gccaaggtta ttctgaatgg aaatggcttt ttcgggtgat
     1921 agaaacattt ttgagccatt caagtgattt ttgaaagtca ctccttcttc agtgatgttt
     1981 cgtgaatcgg ctaaagagta aacttgaaaa ccacccgaat cggttaagat tggctgatcc
     2041 cagttcataa acttgtgcag accaccagag cgagcaatca actcatctcc tggacgcaac
     2101 cagaggtgat aagtgtttga taaaataatc cctgatccaa ttgcttttaa ctcttctgga
     2161 gactgtgttt taacagtagc ctgagttccc actggcataa acattggtgt cggaaaggtc
     2221 ccgtgagggg tgataatttc gcccaagcgt gcaccggtgt gcttttctgt tttgataagg
     2281 cgatacttaa tcggataatc tgtcatgtgc tttcttcctt gctatcaaga taaacagtct
     2341 tgagcttttt tgatctgcct gagtttccat cataatgaag ggcttcaaga tgacatgttg
     2401 ttctagcgcc tatcatttta tcaaaaaatc cataatttgt catgctttcc caaaaaagta
     2461 tagtcaaaat aatggttagc tgtctcattt tgttttatgg tataatgaaa taaaggagtc
     2521 tgttatgtca attaaagcaa tcaaaggcca ggctagagac acgttaaaaa atctctctgg
     2581 caagtattta ctatttttaa ttccaaccct tctctttatg tttcatttcg gtattgagat
     2641 tcatcaaggt tacgtcctat ctagtggtat tgaagtctcg ctagcggcta gttatttccc
     2701 attactacta ggacttatcc ttagcctttt cattttatca gcatccttta cgatgattga
     2761 tgttgttagg cattttcgtc agaaagtttc ttttgccgaa tcaacaacag ccttctcaaa
     2821 agaattcttt gggaacctgc tggttttagc gatcactaag tggctattct ttctcatctg
     2881 gtcactaatt tggttttttg gcctctttat tttcctttcc ggactttcag cgtttttggt
     2941 caatgctaaa tcaggtggct caacagtcat ttcactgatc tttttactat ttggagcagt
     3001 tttgtcctta attggttttg gtatttatat caaccgttat tacgcttata gtctatcaga
     3061 ataccttctc tacgataagg ttaaagaggg gacttatcta ggagctatag ccgtcattga
     3121 aacaagtgta gctatgatga aaggttataa atggaagctt tttttcttac aacttagctt
     3181 caccggttgg tttctactga atattgttac ttttgggtta cttaatatct atcttttacc
     3241 atattttaca acagccaatg tcatttttta tgatcaactc aagaaacgtt tcaaagacaa
     3301 agatgaccca attgaaggag aacatttaag ccttcatcag cttaataaaa agcctactcc
     3361 tatgatgtat gacgatcaaa aagactaaat aaatcctcca tccataaaaa tagcccttga
     3421 actgcacccc aaaagttaga cacaaaatct aacgattggg gtgctatttt tttatgaaat
     3481 ttaatcaaga aacgaaagtt aagatttatg agttacggca aatgggagag tccattaaat
     3541 ccatatcaaa aaagtttgat atggcagaat ccgatctcaa atatatgatt cgcttgattg
     3601 ataggtatgg ggtaaccatt gttcaaaaat gtaagaatca ttattattct ccagaactga
     3661 agcaaaagat aataaataaa gtcctgattg acggccaatc tcagaaacaa acatccttag
     3721 attatgcttt accaacttct agtatgctct caaggtggat agcgcaatac aagaaaaacg
     3781 gttatactat tcttgaaaaa ccaagaggga gaccgagtaa gatggggcgt aaacgtaaga
     3841 aaaatttgga agagatgaca gaggttgaac gtcttcagaa ggaattagaa taccttagag
     3901 cggagaatgc tgtgctaaaa aagctgagag aataccgctt gagggacgaa gtaaagctca
     3961 aagagcaaca gaaatcattc aagcattaag gaatccattt cccttagaga tgctacttga
     4021 aatccttgat ttatcacgct ccacctatta ctatcaagtg aagcgactag ctcaaggaga
     4081 taaggatata gaactaaagc atgtgattcg agagatttat gatgagcata aaggtaatta
     4141 cggttatcgt cgtattcata tggagttgcg taaccgagga tttgtggtca atcataagaa
     4201 agttcaacgt ctcatgaaag tcatgggcct agcagcccgc attcgtcgga agcgcaagta
     4261 ttcttcttac aaaggagagg ttggtaagaa ggctgataat ctgattaaac gtcacttcga
     4321 aggctctaaa ccttacgaaa aatgttacac tgatgtgacg gagttggcct tacctgaagg
     4381 aaaactctac ttattacctg ttcttgacgg ctataacagt gagattattg atttcactct
     4441 gtctcggtct cctaacttga aacaggttca aaccatgctt gagaagactt ttccagcgga
     4501 ttcatacagc ggaactattc ttcatagtga ccaggggtgg caataccaac accagtccta
     4561 ccatgatttt ttagagtcta aaggtatttt gccatccacg tcccgcaaag ggaatagccc
     4621 ggataacggc atgatggaat ccttctttgg cattctcaaa tctgaaatgt tttatggact
     4681 cgagacaact tatcaatcac ttgacaagct tgaagaagct attacagatt acatttt
//
LOCUS       DAUGUF010000060         4507 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUGUF010000060 DAUGUF010000000
VERSION     DAUGUF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4507
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.060"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..141)
                     /locus_tag="VIB71_001632"
     CDS             complement(<1..141)
                     /locus_tag="VIB71_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEQ8823351.1"
                     /translation="MDEFKGIKVEFIQLSNKNIFDVLEKDLSKKLRFEDISIEAILGK
                     YLC"
     gene            complement(118..252)
                     /locus_tag="VIB71_001633"
                     /pseudo
     CDS             complement(118..252)
                     /locus_tag="VIB71_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
     gene            complement(357..629)
                     /locus_tag="VIB71_001634"
                     /pseudo
     CDS             complement(357..629)
                     /locus_tag="VIB71_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(648..953)
                     /locus_tag="VIB71_001635"
     CDS             complement(648..953)
                     /locus_tag="VIB71_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ8823352.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQEM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(953..1255)
                     /locus_tag="VIB71_001636"
     CDS             complement(953..1255)
                     /locus_tag="VIB71_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEQ8823353.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLISSFEDAKTGNRKDVREFLSQLKENA"
     gene            complement(1310..1486)
                     /locus_tag="VIB71_001637"
     CDS             complement(1310..1486)
                     /locus_tag="VIB71_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ8823354.1"
                     /translation="MGQNVVMRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCIRRQG
                     DEASVYDERGILSF"
     gene            1502..2395
                     /locus_tag="VIB71_001638"
     CDS             1502..2395
                     /locus_tag="VIB71_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823355.1"
                     /translation="MTTMLDFPFHHEFIEFLGRWTHILITLLKRHHGQADTAIPRYLL
                     VTIREKTGIVKSTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEPLNLIALCPDCFLSYQADSRKKIVTALKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTLYQLVKNPVI
                     DNYLTIQKIIVNLDKQGKIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHKATL
                     QDIYFCQTIVSYFIQKCEVLE"
     gene            2395..2619
                     /locus_tag="VIB71_001639"
     CDS             2395..2619
                     /locus_tag="VIB71_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823356.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            2610..3782
                     /locus_tag="VIB71_001640"
     CDS             2610..3782
                     /locus_tag="VIB71_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEQ8823357.1"
                     /translation="MLIEMWSPVFKNHGEIRESICFHYGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSGDTANPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYTFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDIEKNQQKLQLRNTKLELESSLRDKQRRLKLLDISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLETILDSEFSTERESLIAEIDEL
                     ESQLTTLNQELQELGNIPNLSSEYLENYSKLTATINALKEQNEAYLKESGLSKEKS"
     gene            3795..4268
                     /locus_tag="VIB71_001641"
     CDS             3795..4268
                     /locus_tag="VIB71_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEQ8823358.1"
                     /translation="MKRSTEDILLDLEVKINSKMREVNNILYPDIRKAPQINLNAHNS
                     YSFYTPDDDGTGTKFKGMIVFDLVMLYLTNLPALAHDSLLLSNVSYQATEALLKLYDQ
                     SRSLNKQVFLAFDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            4258..4467
                     /locus_tag="VIB71_001642"
     CDS             4258..4467
                     /locus_tag="VIB71_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8823359.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
BASE COUNT         1522 a          913 c          746 g         1326 t
ORIGIN      
        1 acacaaatat ttacccaata ttgcttcaat tgaaatatct tcaaatctta actttttaga
       61 taaatctttc tccaaaacat caaatatatt tttgttagac agttgaataa attctacttt
      121 aattccttta aactcatcca cattctcgcc actagtcgtg cgaccaaaga ggtagaaaaa
      181 gtcctgacct tcataactgt tttgaggctt atctctagcc ctttttcttc caattaaatc
      241 aagtagtccc ataagccctc cttattttgg ggtacaaaaa aagcacctcc tttgaagtgc
      301 tttcggtata tttctttcaa agtaatcaac agtctttctt acaaaaccta gtattctcat
      361 tctgtcaatt ccttaaatgc gtcaagatgt cgtgataata ctgaagtcgc aatctcatct
      421 aaccttgctt gttcaacaac tgttgtcatc tgctcatcac tgcttaaact ttggtgatcc
      481 gctgatagtt tgctatcaga tggacttaat accaaagttc catcagttga tttataaagg
      541 ttaaactcct aattctcttg aatgccaaat gggtcaggta tcggaagata gatgtcatca
      601 ccaatttgta tcgtctttac gagttccata catcactctc ccttacttta ccaattattc
      661 atatgacgtg atccatagac gaccgcaaca attataactt catcttccag aacatggtat
      721 acaatgcgat attttttgac aatcagttgt ctgaaggtat agccttttcc aatcagatcc
      781 tcaatgatgg cacaacgttc aggaaaaatg gatagtgata acatttcttg ggataacctc
      841 tcaagaagat tatccgctgc ctgtggtgca cagagttcat cacgaacata gtgatagatg
      901 ctcagcaaat ctgctttagc atcatccgac atggtgacct gatattcttt cattaagcat
      961 tttccttcaa ttgagataga aattctctga catccttgcg gttgccagtt ttcgcatctt
     1021 caaagctgga gataagctta tcataaaact tctcctgact catgtaatca acattaactc
     1081 gttgaggcgc ttcaggtaga gaaacatcaa atgggatacc cccagtcaaa ataatctgat
     1141 tcaaaaacat atcaatcgca gttgacatag gaatacctaa gcgtttcaaa atatcatctg
     1201 ccgcactttt tactgaatca tcaactcgta aattcaaagt tcccgtttta gccatggtta
     1261 tcctcctttt ttgtaacgac attgtatcac gtttttagag ttgactcaac taaaaactca
     1321 atatccctcg ctcatcatag acgctagctt catcaccttg gcggcgaatg caacggtcaa
     1381 gccccaggat aagacctaca ataccgtcaa tcttctcaac agatttttcc ttatctggct
     1441 tgatgttgcc tccaggggct tgtcgcatca ccacgttttg tcccatccat ttaaggactg
     1501 gatgaccacc atgttagatt ttcccttcca tcatgagttt atagagttcc ttggacggtg
     1561 gactcatatc cttataactc tgctcaaaag gcaccatggt caagccgaca ccgcaattcc
     1621 aaggtatctt ctagtaacca taagagagaa gacagggatt gtaaaatcaa ccactgtgca
     1681 aaatactgcg ttcactaccc agtcgaatca gctcaaaaaa caatacgggc agttcttgtt
     1741 aacagaatct aataactgtt gtgcatgccc aggctgtgat agaccactca ttctaaccag
     1801 tggcaactta gcagcagaaa attacgaggt ttcagccatt gaaaaagata aggacgctga
     1861 accactgaat ctgatagccc tctgcccaga ttgtttttta tcctatcaag cagatagtcg
     1921 caaaaaaatt gtaacagctc taaaaaatgt taaaaagatt ctagtctctg cacataacag
     1981 ccaacaagcg atttctgata tgaagttaga cagtggaatt gtttcagttt tgactagtct
     2041 caataaacta aaatgtgatg aatatgatat ctcctatgac tcgaagcaat tgactgataa
     2101 gatatcacct gagaacaatc gtacgcttta tcaattggtt aaaaacccag ttattgataa
     2161 ctacttaacc attcaaaaaa tcatcgtaaa tttggacaaa caaggaaaaa ttgattacga
     2221 ggaaatccaa tatcaaacgc gatcgatgta taaaaagtta aaagcagcca agcataataa
     2281 tctggctatt ttcaatacta tttcggaaaa actccataaa gctacactac aggacatcta
     2341 cttctgtcag acgattgtct cttactttat ccaaaaatgc gaggtacttg aataatgcaa
     2401 ttaccaaata aactttactc ctatcaaaaa agcacccttg cttatttgcc tagagtgcta
     2461 aatgaaatca aaagtggaaa ctcaaacgtc aaagatatct ttcacgctat ctcagaagag
     2521 ttggatgatc ctacagattt cctatctata atggattgct tgtatgcatt gaacgctatt
     2581 gaaatgtcta atgaaggaga agtaaaatta tgcttataga aatgtggtct ccagtattta
     2641 agaatcacgg agaaattcgg gaatcaatct gcttccacta tgggttaaac gtgattatgg
     2701 ggatggattt agctgataac tctatcggca aatcctcctc actattagcc attgatttca
     2761 tctttggagg taatagctat ctaaaatcaa ttgcggttaa aaaattaggt gatcatccta
     2821 tctatttctg ctttcaattt gagaaaaagt tttatttttc aggagatacg gccaacccag
     2881 atatcattct agtgtgtgac aagagctact ctccaaccgg tgaaacaatg gacctaggaa
     2941 tttttcttaa caaacttaag aaacgatatc atttagattc tccagagcta tcattccgat
     3001 tagctatgag tggcttcttt aggattgcag gaaaaagtaa tcaaaatacc gatttccctt
     3061 tacaagttta ttcgagccaa aaatcttctg aatctattac tactctcatc caactgttta
     3121 atttgtatga taacattgca cgatacaaag aacgtctgaa agataagagc gaccagttaa
     3181 caacttttcg taatgctcga aagtatacct tcatctccaa cctggttggc ggtaaaaagc
     3241 aatttgaagc aaatgtctca gaaataaaaa gattggaata tgatttagca catctccaag
     3301 acactcatca agataaaatt gactctgatg atattgagaa aaatcaacaa aaactccagc
     3361 ttagaaatac taagctggag ttagaaagca gtcttcggga caagcaaaga cgtcttaagc
     3421 tattggacat cagtatcgaa tttggcttat atcctactga atctgactta acagagcttc
     3481 aacaatactt cccagatact aatctcaaaa aattatatga agttgaagct taccacaaaa
     3541 aattggaaac tattttagat tccgaattct caactgaacg tgaatcccta atagctgaga
     3601 tcgacgaatt agagagtcaa ttaacaactc taaaccaaga acttcaagaa ctaggaaaca
     3661 tcccaaatct ttcaagtgag tacttagaaa actactctaa actaacagct acaatcaatg
     3721 cactaaaaga acaaaacgag gcctacttaa aggagtctgg tctatccaaa gaaaaatcat
     3781 aagcggacgc tgacttgaaa cgcagtacag aagatatcct tctagatcta gaagtaaaaa
     3841 tcaacagtaa gatgcgtgaa gtcaataaca ttctatatcc agatattcgc aaagctcctc
     3901 aaattaacct aaatgctcac aatagctact ccttctatac accagatgat gatggtacag
     3961 gaactaagtt taaagggatg attgtattcg acttagtaat gctctacctt actaatctgc
     4021 cagcactcgc acacgattca ttactcttga gtaatgttag ctaccaagcg actgaagcac
     4081 ttttgaagct gtatgaccag tcaaggtcat tgaacaaaca agtcttttta gccttcgata
     4141 aagccagctc ttattctcca gatgctaatc aactcttgtc agaaaatacg gtattgagac
     4201 tctctagtaa cggaaatgaa ctctacggta tttcatggaa caaaggagaa aactcagatg
     4261 agatttagtt acaataaatt atggaaactt cttattgata aaggttggac caaaacaaag
     4321 ctcaggcaag aagctgggat tagttcttcc acgatcgcaa aattgggaaa aggggaaaat
     4381 atcactactg atattttatt ggaaatttgt attgcacttg attgtaagat tgaagatata
     4441 gtagaaattg tagataataa tatctagaaa taaaaaaagc actaagttga taagatgtgt
     4501 aagtcag
//
LOCUS       DAUGUF010000061         4443 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUGUF010000061 DAUGUF010000000
VERSION     DAUGUF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4443
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.061"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            20..2293
                     /locus_tag="VIB71_001643"
     CDS             20..2293
                     /locus_tag="VIB71_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEQ8823360.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLHPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEQLSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     GLQTLSQGNSLAQLDQLKAAVSQIASQSNQALPGASSALSELSMGLSKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTVIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADS
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(2410..3483)
                     /locus_tag="VIB71_001644"
     CDS             complement(2410..3483)
                     /locus_tag="VIB71_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEQ8823361.1"
                     /translation="MKNISRKCFMTSVVCIVLGAILLGAGYATGGLQDIKHQTAPKKV
                     IQTFDHVTALDIDTNFSTITVETGPVKKPTVTYYTHSKFIDPLEIKIENETLHISEKP
                     RDVIITGGIELIGFGLNKSDRNHNYRTTTITLPKGTSLKEFKGSSMPQATISDLTVQD
                     LEFSGGLTLLNTRIKKGKVFGTFDATDSLLANLELKADYSLSSLTNSSLENGTISLGH
                     GQLTTKNTNLKSVTIQSLSPGGVEAEETSLENVTFTVTSEQENEETNDNGAIFTAHAL
                     TLKGTNTISGGNVAVDITLTDPKTTAYKTKSEDGKISLGSQLTPAKIGKESTSDVISY
                     VAENKAATGNLTVNLNKGDITIK"
     gene            complement(3480..4067)
                     /locus_tag="VIB71_001645"
     CDS             complement(3480..4067)
                     /locus_tag="VIB71_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEQ8823362.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKENQV
                     IEDLGSPKEAASEIIATVLGKHMASPEKTPEKRATIVGLAILALFAAPIALPVLLALI
                     LFIIACLMAGITAIVAAYVFGLVGVLVAGITLFESLTLLGSSLPAQAMGIGSALLSFG
                     GGILIWIIATALLRFSGRAFVAFIKWISHKKGAQA"
     gene            complement(4054..4380)
                     /locus_tag="VIB71_001646"
     CDS             complement(4054..4380)
                     /locus_tag="VIB71_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEQ8823363.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
BASE COUNT         1324 a          868 c          884 g         1367 t
ORIGIN      
        1 gtccatttta ggagaaaata tgttagaaga attgaaaaca cttattaaaa atccaaaatt
       61 aatgattaca atgattggtg tggccctagt gcctgcctta tataatttat cctttctagg
      121 ctcaatgtgg gatccttatg gtcgggtcaa tgaccttccc attgctgttg ttaatcatga
      181 taagcctgca aagagagctg ataagtcatt gacaattggg aatgatatgg tggacaagat
      241 gtctaaaagt aaagatttag agtatcattt tgtctcagct aagcaagctc aagagggact
      301 taaagaaggt gattattata tggttattac tttacccgaa gatctttctc aacgggcagc
      361 aaccttatta aatcccgaac cccaaaaatt aactatccgt taccaaacga gtaaaggaca
      421 tggaatggtc gctgctaaga tgggggaaac agcgatggct aagctgaaag agtctgtttc
      481 gcaaaacatt acgaagactt atacctcagc agtttttagc agtatgacag acctccaatc
      541 aggattaaaa gaagcctcag ctggaagtca agcacttgct tcaggagcga agaccgctca
      601 ggcggggagt caaacacttt cgacgaactt agcagcctta acgggtgcta gccaacagtt
      661 tcaacaaggt actggtcgat tgacatcagg tttgactacc tatacagatg gtgtcaacca
      721 agtcaagaat gggttaggaa cattatcaac ggacatcccc aattatctga acggggtttc
      781 taggttatcc cagggagctt ctcagcttaa tcagggtctt tcacagttga cacaagcaac
      841 aacactttct gacgagaaag ctaagggaat tcaatcctta attgtaggac taccagtcct
      901 aaatcaaggc attcagcaac taaatacaga gctatcaaca ttgcaccccc ctaaccttaa
      961 tgctgatgag ttaggtaata gcttaggagc tatcgctcaa gctgccaaac aagttattgc
     1021 tgaagagact gccgctcaga atgaacaact atcggctctc caagccacta gtgtttatca
     1081 atcattaact gctgaacaac aaggagagtt agctgcggcc ctcagtcaat ctgataaaag
     1141 tcaaaccgta tctgcagccc aaactatttt aagttctgtt caaacactgt caacaggttt
     1201 acaaactctg tcccaaggaa atagcttagc tcaattagac cagcttaaag cagctgtttc
     1261 acagattgcg agtcagtcta accaggcttt acctggagcg agttctgcat tatctgagtt
     1321 gtcaatgggg ttatcaaagg taaatggtag cttaaatcaa caagttctac caggaagtaa
     1381 tcaattgaca acaggattag cacaattaaa caggtataat actgtcattg gttctggggt
     1441 aataaaactc tcagaaggtg ccaatgcctt gtcatccaag tccggagaat tactagatgg
     1501 tagccatcaa ttatcagagg gtgctactaa actagctgat agtagttctc aattgagtca
     1561 gggtggtcat caattaacga gcggattgac tgaattatca acaggattat caaccttaaa
     1621 tggttcctta gccaaagcct ctcagcagtt atcgcttgtt tctgtgactg ataaaaatgc
     1681 taaagctgtc gcaaaacctc ttgtgttaaa tgagaaagac aaagatggtg ttaagacgaa
     1741 tgggatcggg atggcacctt atatgattgc tgtttctcta atggttgtgg ccctttcaac
     1801 caacgtcatt tttgctaatt ctttatctgg tcgtccggtc aaagataaat gggattgggc
     1861 taaacaaaaa tttgttatta atggttttat ttcgactatg ggatccattg ttctctactt
     1921 agctattcaa ttattagggt ttgaagcccg ttatggtatg gaaaccttag gatttattat
     1981 gctaagtggt tggacgttta tggctcttgt cacagctttg gtcggttggg atgatcgata
     2041 tggctctttt gcttctttgg tcatgttatt acttcaggtt ggctcttcag gtggctctta
     2101 ccccattgag ttaagtggag cattcttcca aaagttacat cctttcttac caatgactta
     2161 tgtggtatct ggtttacgac aaaccatttc attatcaggt catattggag tagaagtgaa
     2221 agtcttaact ggtttcttac tggcatttat ggtattagca ctactcattt atcgtcccaa
     2281 gaaaacagtc taaataaaat aacctcaaaa aaaaacagca tctaaggcag ttacactaga
     2341 tgctgttttt tgtcttattt tgacaataac ttgacaattt ctgtcaagtt ttttattgtc
     2401 ttgttaagat catttgatag taatgtctcc cttattgaga ttaaccgtta aatttccagt
     2461 agctgcttta ttctcagcca cataagaaat aacatctgaa gttgattcct taccaatttt
     2521 agctggtgtc agctgtgatc caagtgagat tttaccatct tcgctttttg tcttataggc
     2581 ggtcgtcttt ggatcggtca aagttatgtc aacagcaaca ttaccaccac taatagtatt
     2641 agtgccttta agggtaagag catgagcagt gaatatagca ccattatcat tggtttcctc
     2701 gttttcttgc tcactagtaa cagtgaaagt cacattttca aggcttgttt cttcggcttc
     2761 aaccccacca ggagatagag attggatggt gacagattta agattagtat tttttgtggt
     2821 taattgtcca tgccctaagc taatcgtccc attttctaaa ctagaattcg taaggcttga
     2881 caacgaatag tcggctttca actcaagatt ggctaacaag ctatcagtag cgtcaaatgt
     2941 cccaaaaacc ttccctttct ttattctagt atttagaagt gtcagaccac cactgaactc
     3001 aaggtcttga accgttaaat ccgatatagt ggcttgaggc atgcttgagc ctttgaactc
     3061 tttaagactg gtaccttttg gaagcgttat ggtagtggtt cggtagttgt ggttgcggtc
     3121 acttttattt aatccaaacc cgatcagttc aatacctccg gtgatgatga catctctggg
     3181 tttttcagaa atatgaagtg tctcgttctc tattttaatt tctaaaggat caataaattt
     3241 agaatgtgtg taataggtaa cggttggttt tttgacaggt cctgtttcta ctgtaatagt
     3301 tgaaaaattg gtatcaatat caagagctgt tacgtgatca aatgtttgga taaccttttt
     3361 aggggctgtt tggtgtttaa tgtcttgaag cccgccagtt gcataaccag ctcctaaaag
     3421 aatggctcct aaaacaatac acacgacact ggtcataaaa catttgcgtg agatattttt
     3481 catgcttgag ctcctttctt gtgactaatc catttaataa aggcaacgaa ggcacgtcct
     3541 gaaaaacgca ggagtgcagt ggcaataatc caaatgagaa taccaccacc aaagctcagc
     3601 aaggcgctac caattcccat agcctgagca ggaagagatg aaccaagtaa agtcaaactt
     3661 tcaaagaggg tgattcctgc aacaagtacc cctacaaggc caaaaacata agcagcaacg
     3721 atagctgtta ttccagccat gaggcaagca ataataaaga gaattaaagc caataaaacc
     3781 ggtaaagcga taggcgcagc aaagagtgct aaaatagcta gcccgacgat agttgctcgc
     3841 ttttcaggtg ttttttcagg acttgccatg tgttttccta gaacagttgc gatgatttca
     3901 ctagcggcct ctttggggct tcctaaatcc tcgataactt gattttcttt atcaggacca
     3961 gcttcatcaa aatattcaat ataatattcc atcgcttcat ggtagtcttc tctaggtagt
     4021 ttgcgcaagt atttatctag ttctgctaga tactcagtcc ttgtcatgtc ttaagctccc
     4081 ttcaataatc ccgtctaagg caaatttata gctctgccat tcttttttta gaaaaatcag
     4141 ctgtgctctc cccgaagaag tgacagcata atatttacgc tttcgtccct gatgttcttg
     4201 actataagtt gtcaaaaaac ctgccttctc caatttttta agaataggat agagggtgga
     4261 ttctttgata ttagccacta gtttaatggt ttgactaata tcgtaaccgt aagaatcatt
     4321 tttttcgaca atggctaaaa tcagaaattc aatcaaggta gccgatactg gaaaatacat
     4381 tttaggctcc ttccatatat aaaaatttta tatataatta ttttacatat ttagtataag
     4441 ctt
//
LOCUS       DAUGUF010000062         4360 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUGUF010000062 DAUGUF010000000
VERSION     DAUGUF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4360
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.062"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            120..533
                     /gene="yaaA"
                     /locus_tag="VIB71_001647"
     CDS             120..533
                     /gene="yaaA"
                     /locus_tag="VIB71_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEQ8823364.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIITIVEPSQEEKEQFAEEMAEKTRVAALVKQMNQANKK
                     TSSKHNNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            535..1641
                     /gene="recF"
                     /locus_tag="VIB71_001648"
     CDS             535..1641
                     /gene="recF"
                     /locus_tag="VIB71_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEQ8823365.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLYQLEKNHQKDFFRKNTSVGPHRDELAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(1696..2559)
                     /locus_tag="VIB71_001649"
     CDS             complement(1696..2559)
                     /locus_tag="VIB71_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEQ8823366.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
     gene            complement(2762..4243)
                     /gene="guaB"
                     /locus_tag="VIB71_001650"
     CDS             complement(2762..4243)
                     /gene="guaB"
                     /locus_tag="VIB71_001650"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEQ8823367.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         1476 a          891 c          733 g         1260 t
ORIGIN      
        1 cttcaaaact aaatagttat ttggacgagt atgatacttt ataaatagct cttattcagc
       61 tattattatt tatttctgtt ttatgctata atgacttgaa tgacaaaatg gagatgacaa
      121 tgatatacaa attatttaca gaatttatca ccctacaagc ccttcttaaa gaattaggaa
      181 ttatccaaag tggtggcgct atcaagggat ttctcgctga aacaaccgtt ctatttaatg
      241 gtgaagatga gaaacgtcga ggcaaaaaaa tcagagtagg ggataagatt tctctacctg
      301 accaagactt aattatcact attgttgagc ctagtcaaga agaaaaagaa caatttgccg
      361 aagaaatggc tgaaaagaca cgtgtagcgg ctctagtgaa acaaatgaac caagctaaca
      421 aaaagacttc ttctaaacat aacaatcgtc aatctactac caaaaaatca ctaagagcaa
      481 ctaagaaaac taaaggtaaa ccaactgcac ctgtccgctt cccaggtatc tagtatgtgg
      541 attaaagagt tagagttaaa acattatcgc aattatgacc acctgcttgc ctcattttcg
      601 tcgggtttaa atgtctttat cggtaataat gctcaaggaa aaaccaattt tctcgaggca
      661 atctattttc tatcacttac tagaagtcat cgcacgaggg ctgataaaga attgattcat
      721 tttgatcact caactgtttc tcttactggt aagattcagc gtattagtgg tactgttgat
      781 ttagaaatca atctatcaga taaaggacgt gtgacaaaga ttaatgcgct aaagcaagca
      841 aaattatctg attatattgg aacgatgatg gttgtgcttt ttgcaccaga agatttgcaa
      901 ctagttaagg gagcacctag ccttcgtcgc aaatttatcg acattgacct tggtcaaatt
      961 aagcctgttt acttatctga gttatcccat tataaccacg tgcttaaaca gcgtaatagc
     1021 tatttaaaaa gtgcccaaca aattgatgcc gcttttctag ctgttctaga tgagcaatta
     1081 gctagctatg gagcccgtgt catggaacat cgtattgatt ttatcaatgc gttagagaaa
     1141 gaagcaaata ctcatcacca agccatctca aatggtttag aaagtctctc tctctcctat
     1201 cagtcgtcag ttgtctttga caaaaaaact aatatttacc aacaattttt ataccaactt
     1261 gaaaaaaatc atcagaaaga tttcttccgt aaaaacacta gcgttggtcc acatcgcgat
     1321 gaattagcct tttacattaa cgggatgaat gctaactttg ctagtcaagg tcagcaccgc
     1381 agccttatcc tttccttaaa aatggctgaa gttagtttaa tgaaggcctt gactggagat
     1441 aatcccattc ttttactaga cgatgtcatg agcgagctag acaatacacg acaaacaaag
     1501 ttacttgaaa cagtaattaa agaaaatgtc caaaccttta tcacaacaac aagtttggat
     1561 cacctgtcac agttgccaga aggtatccgt atttttcacg tgacaaaagg aaccgttcaa
     1621 attgattctg atattcacta ataacatcaa aaaagggttc agttaaactg agcctttttt
     1681 gatattatgt ggcgattaag atttgaccac acctaataaa atagcaccta cgataaaaca
     1741 aataattcct gtgacaaccc aacgcatttc ttttttggtt ttggtttcgc ctaggaataa
     1801 aatgcctccg acaatcgaaa tgatagcacc taattgtgag aaactaaagg caatagcaag
     1861 tcctgctttt gatgcagcta aaagcataaa aatattccca atgccccaaa gtaatccaac
     1921 aacgctattt ttaatcacat actggtcaat ggaaatttta aatgacatga aagttatagc
     1981 tcctaaaacc atacctactg ccatgggtaa aatgactgac aaaacttcaa atttcatgat
     2041 gttattaaat aatacagcat acatcacgta accaattgtt gaataagtga gcgccctaaa
     2101 tccttttgaa aaattatgaa ggtgattgac ttgtgcatta gcatcatctt gtttactaga
     2161 aaagtaaaaa ccaacaatca gaagtaatag tgctagactt cctactacaa attgcatagg
     2221 tcttgtccat tcatgaaaaa cgaggacacc aatcaaactt cccagaacaa gttgagagcc
     2281 acttgacaaa ggattggcaa cggagactcc catgtattgc atggcatgaa attgaccagt
     2341 ttgaccaatt gaccagataa aaccacccaa tattccaaaa agccaaagtt gcagtgtcat
     2401 ctcaggtcta acaattaacc aaacagctaa tgaaaataat aaagccccaa aagtcattcc
     2461 tagagtttgt tgcgaaggtt ttcctccaat tttgttacta acaaatccaa tgcttcccca
     2521 tgtaaacatg ggaataagtg cataaaaaat accttccaaa atgttatctc ctttatagta
     2581 aatctttaaa gattataata attctatcat aaaatggttt catgtaaaga ctaattatag
     2641 cttatttact aagaaaaaac aataaaagtt atccgaaaat tgttattata ttttatcatt
     2701 ttttaatata aaaaaagagc tggcacaata tgtcagccct tagagttact aaattaaatt
     2761 atcagtgcac agaatagttt ggtgcttcgt ttgtgatttg gacatcatgt ggatgacttt
     2821 caatcaagcc tgcacctgac atttcaacaa attgagcatt ttcatgtaat tcttgaatgt
     2881 cacctgcgcc aacatagccc atacctgagc ggataccacc taacatttgg aagacaatat
     2941 ctgaagcagc tcctttataa gcaacacggc cttcaatacc ttctggaact agtttattag
     3001 cttcattgac ggaaccttgg aagtaacgat cgcttgatcc tttcttcata gctgcaatgg
     3061 aacccattcc acgataagtt ttgaacttac ggccttggta gatttcagtt tcacctggag
     3121 cttcatcagt acctgcaaac attgatccaa gcataacagc attaccgccg gctgcaagag
     3181 ccttaacaat atcgccagaa tacttgatac caccatcagc aataatcgtt ttgccatatt
     3241 cacgagcaac agcagcagca tcgtaaatag cagtcacttg aggaacaccg acacctgcaa
     3301 ccacacgagt ggtacagata gatccgggac caatacccac tttaacaaca tcaacacctg
     3361 catcataaag agcacgcgca ccttcagcag tggcaatatt tccagcaatc aaagtacgat
     3421 ttgggaaatg agcacgaatt tcagcaattt ttctaagaac accagccgaa tgaccatgag
     3481 ctgtgtcaat aacaatcgca tctgcaccag cttcaaacaa ggcctcggca cgctcaaaag
     3541 tatctgaggt aacacctacc gcagcagcga ccagaagacg gccaaattca tctttagcag
     3601 catgtgggaa ttcgattact ttttcaatat ctttgatagt gattaaacca gacagacgac
     3661 cgctattatc aaccaaagga agtttttcaa tacggtgttc atgaagaata cgttctgcag
     3721 tttcaagatc tgtaccaaca gcagccgtaa cgaggtgctc actagtcata tgttcagaga
     3781 ttggtgcatt gtaatcagaa ataaaacgca tatcacgatt agtaatgata ccgaccaact
     3841 tacggtttgc taaagtttca acaattggca caccactgat acggtagcgc tgcattaatt
     3901 cttcagcttc tgaaaccttg tgttcaggtg ttaagaagaa tggatcaatg atgacaccat
     3961 tttcagaacg ttttaccttg cgaacttctt ctgcttgctc agtaatagac atgtttttat
     4021 gaataacacc taaaccaccc gcacgcgcaa ttgcaatagc cattttacta ccagtaaccg
     4081 tatccatagc tgctgtaata ataggaatat ttaatgtcaa attgtctgcg agctttgtct
     4141 ttaaatcaac ttcatttgga agaacatgac tctctgccgg aataagcaag acatcgtcaa
     4201 aagtgtagcc ttttttcaaa aatttagtgt cccaatttga catccagata atcctctttt
     4261 cttttatttt tagggaatat taccctggtc tattttttat tgttactatc atatcacgct
     4321 aaaatcattt gtcaataaaa tattcctaca gctgaagtca
//
LOCUS       DAUGUF010000063         4358 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUGUF010000063 DAUGUF010000000
VERSION     DAUGUF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4358
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.063"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            82..624
                     /gene="hpt"
                     /locus_tag="VIB71_001651"
     CDS             82..624
                     /gene="hpt"
                     /locus_tag="VIB71_001651"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEQ8823368.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            646..2625
                     /gene="ftsH"
                     /locus_tag="VIB71_001652"
     CDS             646..2625
                     /gene="ftsH"
                     /locus_tag="VIB71_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEQ8823369.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPKKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMIESESAE"
     gene            2952..4343
                     /locus_tag="VIB71_001653"
     CDS             2952..4343
                     /locus_tag="VIB71_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ8823370.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT         1441 a          628 c          855 g         1434 t
ORIGIN      
        1 aaacttattt gagaaaagct tgtaaacatg atataatgtt ggctaaactg tatattgata
       61 aattagaaaa agggtgacag catgctcgag caagatattc aaaaaattct ttactctgaa
      121 aatgatatta ttcggaaaac taaaaaatta ggagaacaat taacaaaaga ttatcaagaa
      181 aaaaatccgc ttatgattgg tgtattaaaa ggatcagttc cttttatggc agaactaatg
      241 aaacacatcg atactcatgt tgaaattgat tttatggtag tatcaagtta tcatggcggt
      301 acatctagca gtggtgaagt taaaatttta aaagatgtag ataccaatat tgaaggaaga
      361 gatatcataa ttgttgaaga tattattgac accggtcgca ccttaaaata tttacgagat
      421 atgtttaagt accgtaaagc taatactatc aaaattgcaa cactgtttga taaacctgaa
      481 ggtcgtgttg ttaaaattga agcagattat gtttgttaca atattccaaa tgaatttatc
      541 gtaggctttg gtttagatta cgcagaaaat tatcgcaatc ttccttacgt aggtgtatta
      601 aaagaagaag tctattcaaa atagaaaaag gtcaatgttt actgtatgaa aaataataaa
      661 aataatggtt ttgttaaaaa ttcttttata tatatattga tgattattgt tgtcatcaca
      721 ggatttcaat tttatcttaa gggaaccagc acacaaagcc aacagattag ttattccaaa
      781 ttaattaaac atcttaaggc tggagatata aaatctttaa gttatcagcc tagcggtagt
      841 attattgaag ttaaagggaa atatgagaaa cctaaaaaag tgacagttaa ttcaggacta
      901 tcatttttag gcggaagagc ttcaacacag gtaacagagt tctcatcttt agtattacct
      961 agtgatacca tcttgaaaga aatgacagca gcagctgata aaaatggaac agagcttaca
     1021 gttaagcagg aaagttcaag tggtacttgg attaccttct taatgagctt tttacctatt
     1081 gttatttttg ctgctttcat gatgatgatg atgaatcaag gtggtggagg agctcgtggt
     1141 gctatgagtt tcggcaaaaa taaggcaaaa tctcaatcaa aaggtgatgt taaagtgaga
     1201 tttacagacg ttgctggtgc cgaagaagaa aaacaagaat tagtagaagt tgttgatttt
     1261 ttgaaaaatc ctaaaaaata taaatcacta ggagcacgga ttccagcggg agttcttcta
     1321 gaggggcctc caggtactgg taaaacatta ctagctaaag ctgtagcagg tgaagctgga
     1381 gtgccatttt tcagtatttc aggttcagat tttgtcgaaa tgtttgtcgg tgtaggtgct
     1441 agtcgtgttc gttctttatt tgaggatgct aaaaaagctg agcgtgcgat catctttatc
     1501 gatgaaattg acgctgtagg tcgtcgtcgt ggtgctggca tgggaggcgg taacgatgaa
     1561 cgagaacaga cccttaacca attactcatt gaaatggatg gttttgaggg taatgagaac
     1621 attatcgtta ttgctgcaac taaccgtagt gatgttttag atccagcttt actaagacca
     1681 ggtcgttttg atcgtaaggt tttagttggt cgccctgatg ttaaaggacg tgaagccatt
     1741 ttacgtgttc atgctaaaaa taaaccactt gcaaatgacg ttaatttgaa agtagtagcc
     1801 caacagactc caggttttgt aggtgctgat cttgaaaatg ttttaaatga agctgcgttg
     1861 gttgctgctc gcagaaataa aattaaaatt gatgctagtg atattgatga agctgaagat
     1921 cgtgttattg ctggaccatc aaagaaagat cgcactattt cgcaaaaaga gcgagaaatg
     1981 gttgcttatc acgaagctgg tcatactatt gttggtttag ttttatctaa tgcgcgtgta
     2041 gttcacaagg taactattgt acctcgtgga cgagcaggtg gttatatgat cgctcttcca
     2101 aaagaagatc aaatgcttct ttctaaagaa gatctgaaag agcaattagc aggattgatg
     2161 ggtggtcgtg ttgctgaaga aattgttttt aatgctcaaa catcaggtgc gtcaaatgac
     2221 tttgagcaag ctactcagat agcaagggcc atggttacgg aatatggtat gagtgaaaag
     2281 cttggaccag ttcaatatga aggtaaccat gcgatgatgc caggacagat ctctcctgaa
     2341 aaagcttact ctgcccaaac agctcaaatg attgatgatg aggttcgtga actcttaaat
     2401 caagctcgta atcaagcagc tgatatcatc aatgagaatc gagatactca taaattgatt
     2461 gctgaagctc ttctcaaata tgaaactcta gacgctgcac aaattaaatc aatttatgaa
     2521 actggtaaaa tgccagttga tttagaaact gatgataatg aagctcatgc gttatcttat
     2581 gacgaaatta aaaataaaat gatagaatct gaatctgcag aatgatataa aaaagctgaa
     2641 cttatagatt aagttcagct tttttatcaa cacaatatcc ttgtaaacgt tatgaattgt
     2701 aataggtgcc taattgctag aaatgagaag atgatatact ttttttcttt attacttaaa
     2761 gtgagaaaga ctttggtatt taaaactaga aaattgttaa agccatttga aaaaatctat
     2821 tagtgttttc ttataataaa tagaagaaca gaagatagca aaagtttcag tcaaccaata
     2881 agatgaaatt tacaatcatt actaactatg atacacttag tagaaaatca tttactatag
     2941 aaggtgataa catgactatt tttcgtaaaa aaaagaaata ttccaataaa acagaaatgc
     3001 aaaggcactt caaagttatt gatttagttt ttttaggcct aggttcaatg gttggaacag
     3061 gtatctttac agttactggc ataggcgctg ctaagtatgc aggtcctgct ttaacaatat
     3121 cgattatcat ttccgcgatt gctattggaa ttttagcttt attttatgca gaatttgcgt
     3181 ctcgtatgcc ttctaacggt ggtgcttata gttatgttta tgcaaccttg ggagagtttc
     3241 cagcatggct tgttggctgg tatattatta tggaattttt aacagctata tctagtgttg
     3301 ctgttggctg gggaagttat ttaaaaggat tacttgccaa ttataatata gtattaccaa
     3361 acgctttaaa tggcacgttc aatcttaaga atggaactta catagatatt cttcctgttt
     3421 tagtgatgtt tttcgtgaca gggattgtcc taatgaattc gaaattagcc ctgagattca
     3481 atagtttttt agttatttta aaattttcag cattggcttt atttatcttt gtaggcattt
     3541 tttttattga tcacaataat tggtctcatt ttgctccata tggtgtagga caaattactg
     3601 gaggtaaaac aggtatcttt gctggtgctt ctgttatgtt ctttgcattt ttaggatttg
     3661 aatctatttc aatggcagtt gatgaagtga aagaaccaca aaaaacaatt cctaaaggta
     3721 tcattttatc tttgattatt gtaacagcac tctatatagt tgtcaccact attttaacgg
     3781 gaattgtaca ctacactaaa ttaaatgttc cagacgcggt ggcttttgct ttaagaaata
     3841 ttagacttta ttgggcagct gactatgtgt cgatagttgc tattttgact cttattacgg
     3901 tatgtatttc tatgacctat gcattagcta gaacaattta cagtattagt agagatggtt
     3961 tattacctaa atcactttat actctcacta aaaaaaataa agtgcctcaa aatgctactc
     4021 ttgtcactgg actacttgct atgatttgtg cgggaatatt tcctttatcg agtctagcag
     4081 agtttgttaa tatttgtact ttagcatatt taattattct gtcgggtgca attattaaac
     4141 tcagaagaat agaaggagaa ccaaaagcaa atgaatttaa aactcctcta gtaccattcc
     4201 taccaatgtt ggcaattatc atttgtctat catttatgag ccaatataaa gcttttactt
     4261 ggattgcttt tgctattgcc acaattattg ggacattaat ctacttagct tatggttata
     4321 ctcattcaat agaaaataaa taatgttttg ataataag
//
LOCUS       DAUGUF010000064         4325 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUGUF010000064 DAUGUF010000000
VERSION     DAUGUF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4325
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.064"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(149..1171)
                     /gene="trpS"
                     /locus_tag="VIB71_001654"
     CDS             complement(149..1171)
                     /gene="trpS"
                     /locus_tag="VIB71_001654"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEQ8823371.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIRIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     misc_binding    complement(1226..1467)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1590..2462
                     /locus_tag="VIB71_001655"
     CDS             1590..2462
                     /locus_tag="VIB71_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ8823372.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     gene            2541..4160
                     /locus_tag="VIB71_001656"
     CDS             2541..4160
                     /locus_tag="VIB71_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ8823373.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
BASE COUNT         1347 a          792 c          749 g         1437 t
ORIGIN      
        1 aaaaaattca tttgggtctt atttttaatc aaaaataaga ctatataaaa cataatctct
       61 actatcctgt aaagaaatga caaattaggt cctgctttga taatagtaat tatcttatca
      121 ttactaactt agctttttct ctaaaacatt aaaaataatt aatacccatt gctgacttca
      181 cttctgataa agtcttggct gccacagttc ttgctttttg actaccttct tgtaacatac
      241 ggaacacctc tcccatatct ttagcgtact ccaaacgtct ttcacgaata ggtgctaatt
      301 cacgttctaa aatatctaga aggtagcgtt tcgttttcac atctcctaaa ccacctcttt
      361 gataatgctc tttcattgct tcgatatcag cttgatcttc ttttctagca aaaatatcca
      421 aataatgaaa gaccatattc ccttcaattt gaccaggatc ttctattcta atatgatttg
      481 gatcagtata catgctcatc acttttttgc gaacggtatc tgcatcatct gaaagataga
      541 ttccatttcc caatgattta gacattttgg cattgccatc aagaccaggt aagcgtccag
      601 ctttttcatt ttctggataa ataccttcag gttctactaa acagtctgta tggtaagtat
      661 gattaaaact tctcacaatt tcacgtgttt gttcaatcat cggtttctgg tcgttaccta
      721 caggtactaa attcgcttta aatgctgtaa tatcagcggc ctgtgatact ggataaacca
      781 aaaaaccaga tggaatactt tcgccaaaac ctttctgagc aatttcggtt ttaacagtgg
      841 gatttctttc caaacgtgct aatgatacca gattcatata atacatgctc aattcagcta
      901 gctctggaat ctgactttga ataaaaatcg ttgattgctt cggatccaaa ccaacagaga
      961 ggtaatccaa ggcaacattt ccaatagatt cttgaattaa ttcggattct ttagcatgat
     1021 ccgtcagtgc ctgttgatcg gccaagaaaa caaacatctt atacttgttt tcattttgta
     1081 aaaagacacg atttttaaga cttccgacat aatgacctaa atgtaatttt ccagttggtc
     1141 tatctccagt taaaataata ggttttgtca tcattttctc cctaactatc tcttgatata
     1201 gcaaaaagtc cccacgctat taaaacgtga gggcgttatt acaagtaata cgcggtacca
     1261 cctcaattag catctgcttt atcaaaacga gatactatct caatcttctc aatgaaagaa
     1321 gctgcacggt aaggggtgcc aacctgaaag ttatggtttc ctttcaaata atcattagtc
     1381 catttcacct tttctgttgt tagcttgcac caaccactaa ctctctaaaa acatgaaaag
     1441 aatactcttc taattcaaat ttattctatg aaattttaaa cttcttgtca agttcaccag
     1501 attttttgaa aatatgactt gacggtctca gtacatttaa gagataatga gtctactatt
     1561 tttaaccagt tataaaggag attaaaagca tgaaaaaacg agggattgat ttactacttg
     1621 tcacaattgg ctcattcata acagctattg gtttcaatac aatgtttgtc gacaatcata
     1681 ttgcatcagg gggtatggtt ggtattgcag ttgttataaa agctctattt ggcattagtc
     1741 cgtcgctttt tttaatggct agtaatattc ccttattatt aatgtgttac ttctttcttg
     1801 gaaaacaaaa ttttattaaa acactttatg gttcttggat atatcctatt gccatccgtt
     1861 caaccaattc attacctact ctgacacaca atcagttgtt agcagctatt tttggtggta
     1921 ttatctgtgg cattggttta ggaatggttt tttggggaaa ctcttcgaca ggaggaactg
     1981 gaattctaac acaaatactt cataaatact ctcctttatc tcttggagtt gcaatgacaa
     2041 ttgtagatgg tattagtgtc cttatgggat ttattgcact ttctgcagat gacgtgatgt
     2101 attctacgat tggacttttc gtaattggtt atgtgattag cgttatggaa aatggctttg
     2161 actcatccaa aaatgttatg attatttcca aagattatca agctattcga gaatatatca
     2221 caactgttat ggatcgtgga gtgactaaac ttcctattcg cggtggttat actacttctg
     2281 ataaaattat gttaatggct attgtatcaa gtcacgaatt acccactctc caagaaaaaa
     2341 tcctcgaaat tgacgacaca gcctttattg ttgtcatgcc agcagctcaa gttatgggaa
     2401 gaggatttag tttgactaaa caatacaaac gtgaagataa agacgtttta ttgcctatgt
     2461 agtgattagc ccttttctga ttgaaaaagg ggactatttt aggtacaatg aagcttagat
     2521 aaataaaatg aggtgacaaa ttgcttacag tttctgatgt atcactacgc tttagtgatc
     2581 gaaaactatt tgatgatgtt aatatcaaat tcacagccgg caatacttac ggcttaatcg
     2641 gtgcgaatgg tgccggaaaa tcaacttttc ttaaaatcct tgcaggagat attgaaccaa
     2701 gtactggtca tatctcttta ggacctgacg aacgcttatc tgttcttcgc caaaatcatt
     2761 ttgattatga agaagaacgt gcgattgatg ttgtaatcat gggtaatgag caactttaca
     2821 atatcatgaa agaaaaagac gctatctata tgaaagcaga tttttcagaa gaagatgggg
     2881 ttcgtgccgc tgagctagaa ggtatctttg ctgaattagg tggctgggag gcagaaagtg
     2941 aagcttctca acttctccaa aatctaaata ttccagaaga ccttcactac caaaatatga
     3001 gtgaactggc taatggagat aaagtgaaag tccttcttgc taaagcgctc tttggtaagc
     3061 ctgacgtttt attacttgac gagccaacca atggtcttga tattcaatct atttcatggt
     3121 tggaagattt cttgattgat tttgaaaata cagtcatcgt tgtttcccat gaccgtcact
     3181 tcttgaataa agtatgtact cacatggccg accttgactt tggtaaaatc aaactctttg
     3241 tgggtaacta cgatttctgg aaacaatctt ctgagctggc cgctcgttta caagctgacc
     3301 gcaatgctaa agcagaagag aaaatcaaag aattacaaga attcgttgcc cgtttctcag
     3361 caaacgcatc taaatcaaaa caagcaacct ctcgtaaaaa aatgcttgat aagattgaat
     3421 tagaagaaat tgttccctca agccgtaaat acccatttat taattttaaa gcagagcgtg
     3481 aaatgggaaa tgacttcctc actgttgaaa atctttctgt aacgatcgat ggagagaaaa
     3541 tcattgataa tatcagtttc attttacgtc caggtgacaa agctgctatt attggtcaaa
     3601 atgatattca gacaactgct cttatgcgtg ctttagcaga tgatattgac tacgaaggaa
     3661 ccattaaatg gggagtgaca acaagtcgtt cttacttgcc taaagacaat tcaaaagatt
     3721 ttgccacgga agaatctatt cttgaatggt tacgtcaatt tgcctcaaaa ggtgaagatg
     3781 atgatacctt tttacgtggg ttcttaggac ggatgctttt ctctggagac gaagttaaaa
     3841 aatctgttaa cgttctttcc ggtggcgaaa aagtgcgtgt catgctttct aagttgatgc
     3901 tattgaaatc aaacgttctt attcttgatg acccaactaa tcacttagat ttggaatcta
     3961 tttcaagtct taatgatgga atcaaagact tcaaagaatc tgttatcttt gccagtcatg
     4021 accatgaatt tattcaaacg attgctaacc acatcgttgt tatttcaaaa aatggtgtta
     4081 tcgaccgtat agatgaaact tatgacgaat tccttgacaa tccagaagtc caagcccgag
     4141 ttgctgaact ttggaaataa aaccttatga taaatgaggt ggctaagaag atctcttcct
     4201 agcctctttt ttaaaatttg taaacgaaag accatataat ttatgaaaaa taataataaa
     4261 tggataattg ctggacttgc tagttttttg ttccctctta gtattatatt tatcatcctt
     4321 ctatc
//
LOCUS       DAUGUF010000065         4317 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUGUF010000065 DAUGUF010000000
VERSION     DAUGUF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4317
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.065"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..133)
                     /locus_tag="VIB71_001657"
     CDS             complement(<1..133)
                     /locus_tag="VIB71_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEQ8823374.1"
                     /translation="MIDFIISIDDCAVELDSRQSWKIRYPLSTILFLVFVCQLAGIET
                     "
     gene            688..2196
                     /locus_tag="VIB71_001658"
     CDS             688..2196
                     /locus_tag="VIB71_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ8823375.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRIPS"
     gene            complement(2545..3894)
                     /locus_tag="VIB71_001659"
     CDS             complement(2545..3894)
                     /locus_tag="VIB71_001659"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEQ8823376.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
BASE COUNT         1294 a          842 c          750 g         1431 t
ORIGIN      
        1 aggtttcaat gccagctaat tgacaaacga agacaagaaa tagaatggtt gataaggggt
       61 agcgaatttt ccaagattga cgactatcca attcaactgc gcaatcatca atagaaataa
      121 taaaatcaat catcgtagtc acctcatcta tagtgtacta ctttgattga ttttgtcatt
      181 atgaatctag ttttctgaaa acaaaagttt cttcatgcgt ttggcgtgga aactagctct
      241 ctcaaaaaag attaaaaata aaggcattct aaagaatcat ttaagaaaaa tttaaggttg
      301 ctatcgtaga atgaaaacat cctaaaaagc ggtttaccta aaccgttggg agaataggtt
      361 ttccccttgt tttccctttt cataaatctc ctgggcacct atcttcttag gtgccctccc
      421 ttgtttaaac ctgaccagtt aaccggctgg ttaggttttt aaatttaaaa agtcaacagc
      481 aaaaatatga tatcacccgc gtgttcttag ctctctcaat tatgggctaa aaacacgcat
      541 caatcaatct attgatgaag tttgctgctt tttgatgatc tttattgtga ctatactggt
      601 aatcctattg attttagttg acttttacgg tagattcgct acaatatata ggattataca
      661 atttaattta aggagagaaa aattacattg ttagattatt atttggaatc cgatattatt
      721 gaccagaaaa tcctactggc tattttgttg acagaaaaag aactgacgat ggcagcagct
      781 tgttctcaaa caactttgac tgctttaaaa ataaagcagt atcttcgaca atttaacgcc
      841 ttatttaaag ggtacttacg tattgagctt attaaatctc gtatttattg tgaggtatta
      901 aatgataagc gagaagcatt tttttatgat atttttgcct tatcagatac tctaaaaatg
      961 ttgacattct tattactaga taatcccaaa cacaagtcaa tcgctgttta tacacgaaaa
     1021 caagggatat cccagtcaaa agcttatcgt cttattcata aattaaaaca ttatttacaa
     1081 gacattggtt taaatattgt agacaatact gttatcggag atgaacttaa aatacggtat
     1141 ttgattgctc ttttacataa agagtacggc attatattat atgatataca acctgcagac
     1201 attgaaacga ttcatgcttt tatctttgca gcacaaaaaa acttacaacc ttctgccttt
     1261 ttagatagac gcttcttgtt ttttgatgtg ctgttgatgt tgacttggaa gcgccatcgc
     1321 tatcctgttc atttgcctca tttagctctt tttgaacatc tcaaatcctt gcctattttt
     1381 gacaatatca aaaccattgc cgtggatgag ctagcacctc gaactcgtgt cacattttcg
     1441 tctgatgatt ttgactatct ctttttaatt tatttaacga ctgataactc cttcttgagt
     1501 gggtactgga caagtcatca gcgacaacaa ctttaccatt taatcaccaa agatcccgat
     1561 tatcatttac taattcatcg tcttcaggca ctagttggaa aatattccga tattcatgag
     1621 catatcccta acttaattcc ttttttcaaa agaactctct acaatttaca aactttaatt
     1681 acctttgatg gttattattt tgatcaatat caaggcaaca tgctactact agataagctt
     1741 gaaaccgtta tcaaagattg gctttatgac acaggccgtc aaggcagtat tagttctggt
     1801 cacttacact tgatgtgttt ataccttgag cagatcttgg aaagctctat tgctccaatc
     1861 aatattactg ttattgagag ccaagaaact gttggtaacg tcatagctaa tttcatcacc
     1921 tcaactatcc cttcttacaa agttgaactg tcacgggtca atatcttatc tgataatatt
     1981 tatccctatg ataaacctgt agatctggtt gtgaccagtc aaaagctctt gcctttttta
     2041 aaagaactcg gtgtttttcc caaagagacc cgcttgtttg gtttgagttt ggactgtatc
     2101 caacagcagc gcgaagattt aatcaaaacc atcttagcct tgcaccagaa ccactaccaa
     2161 aaacgtttag aagaactttg gagaattcct tcttaatttt ttgacagacc ctcctagata
     2221 ctttcacagt ctaggagggt ctttaaggtt gtcacttgca accttgataa gctctctttt
     2281 taaccattgc tatttgccta gaaacagaac tggaactgtt ttagcggttc aactcctctt
     2341 gtaggatctt cttccctttt ttgaaggtct tatctgaaat ttggcataat aaagtgcgct
     2401 cccatgttct ggaagcgcac tttattatcg cttttactta accttgtatc cacttgatga
     2461 tggaagtgcc gccccaattc ttagattgct tggctaactt ttaagctctt gtacaaggaa
     2521 gaagtctttt tgactatctg ttgattagag gcgagcatta agctctgctg ataatgcttc
     2581 aaaacctggt tttccaagaa gcgcaaacat gttacgtttg taagcttcaa cacctggttg
     2641 atcaaatggg ttaacagcat tcatgtagcc tgaaaccgcg atagcaagct caaagaagta
     2701 aatagtgtaa ccaagggtaa attcgtcttg agctggaaga gtgacaaaca tgtttggcac
     2761 gccgccatct gtgtgggcaa gaagcacacc atctgtagct ttcttgttaa cgaaatcaac
     2821 gtctttacct tgaaggtaac caagtccatc taggtcttct gctaattcag gaatgataac
     2881 atttttacga ggtttatcaa cacgaataac tgtttcaaag aggttacggt aaccttcttg
     2941 gataaattga ccaagtgagt gtaagtctgt tgagaagtta gctgaagttg ggtaaatccc
     3001 tttttggtct tttccttctg attcaccggc taattgtttc caccattctc caaagtattg
     3061 aagagatggc tcgtagttag ccaagatttc agtgatgtag cctttacggt aaagcacatt
     3121 acgaacagca gcgtattggt aagcaatgtt ttcagagatt ttgtctgaag aaaggtcttt
     3181 acgcgctgca tttgcacctt ccataagagc tgtgatatct gcacctgatg cagcaattgg
     3241 aagcaaacca acagcagtca agactgagaa acgaccacca acgttgtctg gcaccacaaa
     3301 tgtttcccag ttgttagcgt cagcttctac cttaacagca cctttcactt tgtctgttgt
     3361 agcgtagata cgtttgttag cttcttcttg accatatttt ttaaccaaaa gttctttgaa
     3421 gacacggaaa gcaatcgctg gctcagtagt tgttcctgat ttagaaatca cgtttactga
     3481 gaactctttg tcttgaacgt actctacaag gtctgctaag taagttgatg aaatagagtt
     3541 tccagcgtaa agaatttgtg gggctttgcg ctctttggca gtttgtaagt tagcaaaatg
     3601 atgatttaaa aaatcaatcg ctgctttggc accaaggtat gacccaccga taccgatcac
     3661 cacaagaact tcgctgtctg acttaatttt ttcagcagca gtcaagatac gtgcaaattc
     3721 ctctttgtca tagttttctg gaagatcaag ccaacccaag aaatctgaac ctggtccagt
     3781 tccttcacgc aataacttgt cagcttctgt gacttggcct tgtaaaaaat caatttcatg
     3841 ctgtcccgca aatgactcga ggacttttga ataatcaaat gtaatatgtg acatgagttt
     3901 cgctccctta aaattttaag tttcattagt atgataacct tttctatcta atatttcaat
     3961 ggtttttagt ggttttcacc tgtgaaaaag ctaggttttt tgaaaaggtt ttcgtttttt
     4021 cagacctaaa acatgtgtca atgcaagcat attctcatca tagtggtttt ttaagagaaa
     4081 ataggatttc atatttccta aaaatatcat gaaaaaaggc cctgaggccg ctttaccgta
     4141 ataacttatt ttaaggattt tatcatttca atacgggtaa taaccccatc atgcatatga
     4201 tcaatgcata aagccacacc tacaaaggca attgaagccc caatcacctg taaatacttt
     4261 ctcatgctat cttcttaaca ttacttactc tcattatcta aaaatggcaa tcatttg
//
LOCUS       DAUGUF010000066         3896 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUGUF010000066 DAUGUF010000000
VERSION     DAUGUF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3896
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.066"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(155..3658)
                     /gene="scpA/B"
                     /locus_tag="VIB71_001660"
     CDS             complement(155..3658)
                     /gene="scpA/B"
                     /locus_tag="VIB71_001660"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEQ8823377.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPVTEQA
                     VETPQPTAVSEEVPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATI
                     RDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAK
                     KEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGA
                     MPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETK
                     KAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPD
                     KQLTETAMVKTDDQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIE
                     RGDIDFKDKVANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDNP
                     QKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKL
                     SGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFS
                     PRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYY
                     QATVQTDKVDGKHFALAPKVLYEASWQKITIPANSSKQVTVPIDASRFSKDLLAQMKN
                     GYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSAVEKPIYDSKDGSSYYHEANSDA
                     KDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTF
                     AKQDDDSHYYIHRHANGEPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNV
                     VWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISS
                     GAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDED
                     LPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEG
                     HSNKPEQDGSGQTPDKKPEAKPEQDGSDQAPDKKPEAKPEQDGSGQTPDKKPETKPEK
                     DSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTRDQLPTTNDKDTNRLHLLKLVMT
                     TFFFGLVAHIFKTKRQKETKK"
BASE COUNT          965 a          786 c          811 g         1334 t
ORIGIN      
        1 catcttttat cacagcaact gaaaagataa gcaaaaggca attgttgaca gctatttgtc
       61 ctaacttctt tttgatgagg cagcacatct aaaaaaatag agagaaccaa attggttctc
      121 tctattaaat aagctcttat cagtttaagt aatactattt tttagtttct ttttggcgtt
      181 ttgttttaaa gatatgagct actaatccaa agaagaaagt ggtcataact aacttaagga
      241 gatgtaaacg atttgtatcc ttgtcattag tcgttggtaa ctgatctctt gttgatgctt
      301 ttgtagctaa agcacgctta gaagagcgtt tctctagagt acgagaaggt tgaccttttt
      361 gaggagtttt acctggtgtt tgacctgaac tatctttttc tggtttagtt tctggttttt
      421 tatctggtgt ttgacctgaa ccgtcttgtt ctggtttagc ttctggtttt ttgtctggtg
      481 cttgatctga accgtcttgt tctggtttag cttctggttt tttatctggt gtttgacctg
      541 aaccgtcttg ttctggctta ttagagtggc cctccaatag cttagtcact ggtgtataag
      601 tgatattacc agccatatct tcaacaacat aagtaaagtc tgacattttc aatggaacag
      661 tagcgccttc cattgtttca gcctcttcag gaagagtaaa ggtaccatct tcatttggag
      721 aaatatactc tgttgttggc agatcctcat ccatataagt gtaagcaata cgctcacggt
      781 aaaccggttg gctggttttt ggtttagatg caagtgtcaa acgacgatct tctgttgaga
      841 atgttgccga tgttgcgact tcaggtgtcg tattgtctac aatcacatca aaatcagtgt
      901 gttgttcttt tgcacctgaa ctaatcggag tgtagcggac acgataggtg taggttccgt
      961 tagcaacaac tttgccgtct ttatctttac cgtcccaacg agttttttca aaacgggttg
     1021 aaccaagtgt gcttgccaag tcattgttgt agtttttaac aacttgctcg gttacctcac
     1081 ttgtccaaac aacatttcct tctttgtcca agacttcagc cacaaggttt ttagcattac
     1141 gcaagaaagt accttggaat tggacataat ctctgttacc gtccccattt ggagagatcg
     1201 cagcatatgg ctcgccatta gcgtgacggt ggatatagta gtggctatca tcgtcttgtt
     1261 ttgcaaaagt acctgcaaaa atggtttctg tgatctctga agattcgata tcctctatgt
     1321 tttcaactcc ttctttgaca gccttaataa tcgtccatgg gttagactct gtggtaagtg
     1381 ctgtaaagtt gtttttcaga gcgtaaaact gtaatccatc accatctaat tggtctttgg
     1441 catcactatt tgcttcatga tagtagctgc taccgtcttt gctatcatag attggttttt
     1501 ctacggctga cagattgcca aaatcacctc ggaaaccaat atatggaatg ctcataagct
     1561 cttcttttgt aggatcttgt ttgaaacgaa caaaaccttc taagaaatag ccatttttca
     1621 tttgggcaag caagtccttg ctaaatcgac tagcatcgat tggaacggtg acttgtttgc
     1681 tgctattggc tggaattgtg attttttgcc atgatgcctc atacaatact ttaggagcca
     1741 aggcaaagtg ttttccatct actttatctg tttgaacagt tgcttggtaa tacaactctt
     1801 gaggtttatc agatttgttg tgaacagtta ctgttacttc aaatttatca gaaacattgt
     1861 tcaggtgaac cttgcttgag gtattatcct tatctgtcac atacatcgtt gctgctgaag
     1921 cttttttagc atcgaccgct cctgctcctt gttggcgagg agaaaaataa gctttttcat
     1981 cttcatcata taaggcagtt gctgagctca tcaatacttt tttagctaaa tcaagacgct
     2041 ctgatggtgt catatcagga tactgtgtct catattgctt ttgcaacagt cccatgatac
     2101 ccgctactaa tggcgcagac atactagttc cagaaagttt ggcatacttg ttgttagcca
     2161 ctgatgacaa aatatcttgg ccgggtgctg caatatctgg cttaatattg ccgtcagctg
     2221 tcagacccca gcttgagaag cggcttagtt tggtgccact tgctgttggc aataccttag
     2281 gtgtcgcatt gaaggtgatg gttttttggg gattgtcttt taataagaga ccgtcttttc
     2341 gactgataaa ggccgcaggc atctgatcaa catttggcaa ttcaatcggg aagcccttgt
     2401 cctgattgtc atagatcaag acccctacag caccagcttt tttagcgttt gcaaccttat
     2461 ctttgaaatc aatatcgcca cgttcaataa gggcaatctt gcctttgaca tccttaaaat
     2521 catcctcttt catcccacga ttagcataag catagtcgta agccttgttt ggctcaaaac
     2581 ggtttgttga aagaacaggc atttctttat cttgctgatc gtctgttttg accatagcag
     2641 tttcagtgag ctgtttatct gggctgtaag aagcaactgt caatgttgag tctgccgctg
     2701 caggtgtccc aaccacccca taatcaggat gatctgctag aggtagacgg gtcttgcccc
     2761 caaagctact atcattacca gctgaggtca caatgctaac accttttgat ttggcatagt
     2821 caaaggcttt tttggtttcg tctgggaggt tagcgtaggc tagtgcagca ttaccaaagc
     2881 tcatattaat caccttagct cccaagttga cagcatctct gatagcttga gcgtagttac
     2941 gagcatagtc tgctagtcca tttacaattt cgacacgcat caaaagcaat tgagcctcag
     3001 gcatcgcacc ttctaggcgg taaggttctt tcgtttcaga tggagcattt cctgacaaga
     3061 tccctgacac gtgtgtgccg tgctcttgat cgacagcggt tttaccatct ttgctatagt
     3121 cgtggtaata agcaacctta tcattgaccc actcgccata ggtaataccg tgctcttttt
     3181 tagctttttc aagatcttct tttgattggt aacgtgcttt ggttttgtct gttaagcgcc
     3241 acgcttcatg atttttatca aaaccagcat caatcactgc aacaacagtc ccagctccct
     3301 tgcctgcttt ttcctgcagg gttttgacct gagaagggtc gttcaaatcc ctaatagtcg
     3361 cttttgaggt tgctggtgta tcagcagttt tagcaggagc ttgaggggct agatcattag
     3421 cgtcatctgc tattgtttct tctgcgtcat caggagtttg tggggttttg gtttcctttg
     3481 atgatggtac ttcctcagaa accgctgttg gttgtggggt ttctacggct tgttcggtaa
     3541 caggagtgtc ttctgtcaca gtatttgctt taatgtctga ttgtgcattg agcaagatgc
     3601 tcgtagacat gagcgcaatg gcaagtttat caaatggtaa tttttgtttt ttacgcaatg
     3661 tgtcgtcctt tcctgatgag agactttgtc tttatgacca ttaagaaaag agagaatcaa
     3721 acgattctct cctagctgtc catctgtgcg tggagaaata aggataatat cttttttaaa
     3781 gagcaaacag gggttatttg catatgatac agctattttt cttgcttttg ccataatgat
     3841 taaatgtatc tcatttatca attatattac taacatcttt attataaaaa aaagac
//
LOCUS       DAUGUF010000067         3773 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUGUF010000067 DAUGUF010000000
VERSION     DAUGUF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3773
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.067"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            21..821
                     /locus_tag="VIB71_001661"
     CDS             21..821
                     /locus_tag="VIB71_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEQ8823378.1"
                     /translation="MGLTIFKKLVSLIILLLFFAILKRVTNYLFEKTINKSFAYSRQS
                     EARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAGIAGVAIGLGAQGFLS
                     DVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFDGTLHFIPNRSITVVS
                     NKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIVGKPNILGPQNNSNGQ
                     FTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYSITSKS"
     gene            complement(886..1446)
                     /locus_tag="VIB71_001662"
     CDS             complement(886..1446)
                     /locus_tag="VIB71_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEQ8823379.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQFMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(1460..1930)
                     /locus_tag="VIB71_001663"
     CDS             complement(1460..1930)
                     /locus_tag="VIB71_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ8823380.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            complement(1920..2684)
                     /locus_tag="VIB71_001664"
     CDS             complement(1920..2684)
                     /locus_tag="VIB71_001664"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEQ8823381.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            complement(2674..3423)
                     /gene="truA"
                     /locus_tag="VIB71_001665"
     CDS             complement(2674..3423)
                     /gene="truA"
                     /locus_tag="VIB71_001665"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEQ8823382.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
BASE COUNT         1209 a          827 c          556 g         1181 t
ORIGIN      
        1 agcagtctca tatcgaaaat attggcttaa cgatttttaa aaagctagtg tctctcatta
       61 ttctattact cttttttgct attttaaaac gtgttactaa ctatcttttt gaaaaaacca
      121 ttaacaaatc gtttgcttat tcaagacaaa gtgaagctcg caaaaaaaca ctctctaagc
      181 tcactcacaa tattttaaat tacttattgt attttcttct catttattgg atacttagct
      241 tatttggcat acctgtctct agtcttctag caggagctgg aattgctgga gtagcaatcg
      301 ggttaggtgc acagggattt ttatctgacg ttgtcaatgg cttttttatc ttatttgaga
      361 atcaatttga agtaggagat aacgttacta tctctgacat agaaggcagt gtctttggtg
      421 ttggaattag aactactcaa attcgtggat tcgatggaac actacatttc atcccaaacc
      481 gtagcatcac cgttgtcagc aacaaatctc gtggtaatat gcgtgcctta attgaaattc
      541 ctctttattc cactgttaat ttgagccaag tcactcgaat cattgatgaa gtgaatcaaa
      601 aggaattgcc aaaccatcct caaatcgttg gcaaaccaaa tattttaggg cctcaaaata
      661 actctaatgg acagttcact tttagaattg ctattttcac agaaaatgga gaacaattta
      721 agatttacca tactttttat agactttatc aagaagcttt actcaaagaa ggcattcaat
      781 taccgactgc aatcagctat tctatcacct caaaatctta atataatctt aaaaaatcct
      841 tttttctaga aaaaacacca attgttttat tccagaaaaa agggtttagg atttacggat
      901 aatatccata ttgtaatcag ccctagctcc accaattaat tttggtcgac tagccaaagc
      961 tgtcacatga gcacctccta gctctcgttg acaaggaatc agagggatct gaacacgctt
     1021 aatatgcatt cctatagcag tatcacctat atcaagtcca gcgtgtgcaa taacttcttc
     1081 tacttcgaca gggtctgaca taaattgaaa agcagccatc tgagcactgc caccagcatg
     1141 aagattcgga accacattga caatctctaa ctgcttagat tctgccacat gcctctctac
     1201 taccaaggca cgattgacgt gttcacaacc ttgtacagcc aaatgaacac cacgcttatt
     1261 taattcatct aacacaactt caacaactat ttgacctact tctagactag attgttttcc
     1321 aattctacta cccaaaattt cgctagatga aagacctaga acaaaaagat tacctggttg
     1381 aatagcagag cgttctacaa catcaatgac gatttccctt gtttgtttct ctaaattatt
     1441 caacaacttc tcactctcct tatctctttt tttgccttaa tatggcctta aagataataa
     1501 aaccaacaaa aagccctaat gtattttgca tgacgtttcc ccaaataccg gctaaagatc
     1561 ccgaaaggcc ataaccaagc ataagagagc ctaaaaagta ccaaaaaatc atgataaaag
     1621 aacctatcac aacaccaagc caacgcttgc gccctctcca tcccgcaaaa tacccttgga
     1681 cactgtgagc aatcaaacta tgaaacatcc actgagggta tcctgccact aaatcgatta
     1741 aaaaacctga taaccctccc acaatagctc cttgagctga tccaaaggaa aagctgacag
     1801 cataaattcc tgcatccaac agcgttaaaa aacctgttgg agtaggtagc atgacaaatc
     1861 ttcctaaaac aacaaccaat gctgtcaata tccctgttaa actcatttgt cgtatcttac
     1921 tattttgcat aactttgttt tactccgtat ctatcagatt gtaaaatagc ttggtagact
     1981 aactcttttg agtttttcac agcttctagt ggcgtttttt tctttactaa ctgactagcg
     2041 atactagatg caaaagtaca gcctgcgcca atattatttt tctcaagtac aggacattcc
     2101 aaggtaacaa tctctttacc gtcataaaaa agatcaatag cctttttctg actaaatcga
     2161 ttaccaccct tgataaccac ctgttttgcc ccaagttgat aaaaatattt agcagcttct
     2221 tgcatatctt ttaaagaaac aatctctttt tgagataata gctgagcctc taccaaattt
     2281 ggagtaacaa cagttacata aggcaataat tgtaaaatct cctgtcttag aggaactatt
     2341 ttaacatcat ctatttcttt acatgctaga acaggatcta aaaccactgg gattcccaga
     2401 tgccccttta taaaatccaa aactatttca cacatttccg cattaggtaa caaaccaatt
     2461 ttaatagcag aaattggagc gttcgtaaag ctattcaact gatcacggaa aatttcttta
     2521 gctaccggaa atagactaaa gccctcttca gatctagtag ttaaacaagt taccgctaca
     2581 aaggcctgta ggtcatacct tatgtaagtc gctaaatcag catagagacc acctccactt
     2641 aaaatatcgt tcccagatat agtcacgata taatcagttt tcataacaaa tctccttcaa
     2701 gtaaagccca tttccagata tcgttggtcc agctagctga cgatttttgg agctcaaaat
     2761 cactttaact tgttcaactg gcatttgacc attaccaatt ttcagcaaag ttcccaccat
     2821 attcctcacc tgcttataga gaaaaccatt tcctgaaaaa gtaaacacca aaaaatcagt
     2881 tttttcatcc cgagataccg ttgctttggt aatcgttcgc accttatttt gtaccgaagt
     2941 tcctgctgct gtaaaaccag taaaatcgtg tgtacctacc agaccgttaa tagcttcttg
     3001 cataagttta atattaagag tataagggta atgagtggta tagtgtcgca tcatcggatt
     3061 tttaggtcga ccattatcaa ctaaaaattc ataagttttt aaatgcttct gataacgaca
     3121 atgaaaatca tcagccactt tttctatatt aacaacatca atatcttcag gagtctgtgt
     3181 atcaagagca aatcgtaatt tttcaacttc ttgttcttga ggcaaatcaa aatggatcac
     3241 ctgtccataa gcatgtactc ctgcatccgt acgtcctgca ccatgaatta taatttttgt
     3301 accgttattt aatttataga gtgttttttc aatctcttct tgaaccgtac gtaaatgtct
     3361 ttgtctttga aaacccgaaa aaagagtccc atcataggaa atcgttgctt tgtatcttac
     3421 catgttacta ttttaacatt tcttaaacgt aagagaaact atttttaatc aaactgtacc
     3481 caaacaaatg aaagacgtat tgaagcttac tctaagccac tagcgattta aaagctataa
     3541 gaaagctatt tcctccaaac tctctccttt tttcatagat ttacccccca attccttata
     3601 ggtcttgctt acaactgctg tgcaaattcc ttaaaatagg gactgatctt cctaagtaga
     3661 gcacgtcttc ccttgaaacg ttcgcccctg ataagtgctt gaaactgcat acgctcttgc
     3721 gaatttaatt ggttctctaa gctagctatt acctcttgat aagccacata gtc
//
LOCUS       DAUGUF010000068         3763 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUGUF010000068 DAUGUF010000000
VERSION     DAUGUF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3763
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.068"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            77..856
                     /locus_tag="VIB71_001666"
     CDS             77..856
                     /locus_tag="VIB71_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ8823383.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PEGIDPDNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            856..1372
                     /locus_tag="VIB71_001667"
                     /pseudo
     CDS             856..1372
                     /locus_tag="VIB71_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
     gene            complement(1986..3218)
                     /locus_tag="VIB71_001668"
     CDS             complement(1986..3218)
                     /locus_tag="VIB71_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEQ8823384.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPVSKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQSQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDNDAILASLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            3418..3516
                     /gene="ffs"
                     /locus_tag="VIB71_001669"
     ncRNA           3418..3516
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VIB71_001669"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            3618..>3763
                     /locus_tag="VIB71_001670"
     CDS             3618..>3763
                     /locus_tag="VIB71_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ8823385.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENV"
BASE COUNT         1157 a          640 c          803 g         1163 t
ORIGIN      
        1 tttttggtgg gtctcaatcc tctttgacac taatttttgt tataataaga gttaaagcaa
       61 gaaagaaggg tttgagatga aattaaccac cttagggtct tggggagcct atccctatca
      121 agatgcaggc acaacctctt atttggtcac aggacatgac ggctttcagt tattgatgga
      181 tgctggtagt cgagcgctca atgagctgga aaaagaaatc agtcctctcg atttggatgc
      241 agtgattatt agccattacc atccagacca cgtggccgat ttaggcgtgt tgcgccatta
      301 ttttcaactt tatcctaaac acctgtggca gcctaaagta ttgcccattt atgggcatga
      361 tgaggaccga cacgaatttg ctaagttaag cattcctgat gtttcagaag gtagagccta
      421 tgatgtcact ggagttgaac agattggtcc ttttgacatt acctttctta aaacagttca
      481 tccagttgtg tgttatgcct ttcgaattgt agaaagagcg actggtcagg tacttgtctt
      541 tactggagac agtggttatt ttgaaggatt ggcagacttc gcaaaagaag cagacctttt
      601 cttagcagat gtttacttat acgaaggcaa tgaaaatcat atggcccatt tgaccagtaa
      661 ggaagcagga ctaatggcta gccaggcagg tgttaagaag cttgtcttga cccacatgcc
      721 accggttcct ccagaaggta ttgatcctga caatcacttg gaagtgttga ggcaagaaac
      781 acaagcctat gcaggtaata ttcctgttga ccttgcctta ccacacaaat cttggaactt
      841 ggggagtctt tcttgatgcc atatagttta gaagagcaaa cttatttcat gcaagaggct
      901 ttaaaagaag ccgaaaaatc cttacagaaa gctgaaatcc ccattggctg tgtcattgtc
      961 aaggatggtg agattattgg tcgtgggcac aatgcgcgtg aagagagtaa ccaagccatt
     1021 atgcacgctg aaatgatggc tattaacgag gctaacgctc atgaaggcaa ctggcgttta
     1081 ttagatacca cactctttgt gaccatcgag ccttgtgtga tgtgtagtgg tgccattggg
     1141 ctagcaagga ttccgcatgt tatttatgga gccagcaatc aaaaatttgg tggagcagac
     1201 agcctttacc agattttgac agatgagcgc ttaaaccatc gcgtgcaagt tgaacgaggc
     1261 ctgctagcag cagactgtgc taacatcatg caaacctttt tccgccaagg gcgagagcgc
     1321 aaaaaaaata gctaagcatt tgatcaagga acagtcagat ccctttgact agagttttaa
     1381 ggagtttgtt ataacatgca tttttggtga agggtagcct gtcaaaatac tgagtgaaac
     1441 gttagaccat ttttccaatg gttgttagat tcaacatacg aagatagaat atacaaaagg
     1501 gcgtttccaa gtactagaag cgctcttttt cagacccaat cgagatgaaa acaatcgaaa
     1561 aataaaacac gtgatgacta gatgagttgg tcattcttaa aaagatttac tatctaaaaa
     1621 cagatagtaa tggctcacct tatttttgtt tttagtaaac ttatcaagct cagacttcta
     1681 gggctcagag ctgtcagtta tctgtggcgt agattgatac tgacacaggg attaaaaaca
     1741 agtgacttat aggcatggct tgaattattt aatcttttgt cttagctgat atattttgct
     1801 aaagcattaa aaaagagctc atcactgttg ctaatgttac aagcattaga tgtgctcaat
     1861 ctgaaaaggt tatatctatt gaagacggtt agaataataa tcgccttcaa ttgtgttagt
     1921 atatcaattt cttgtaatgt ttgacaaaga taatcatctt aactttgtgt ttcatgtgtc
     1981 taaacctagt tcctactagc aaatgaaata ctaagagtct ctggtaagag tccataggta
     2041 aagcccgtat aattattcca atactgattg aaaaggttat gataacctgt ttgattcgtc
     2101 gttaaatcag ttaccatttg ttgataatca tcttgatgag caaattgtag agacagtggc
     2161 tcttgtctat ttaacaactg attttcaagg cttgcaagga tggcgtcatt gtcaaacgtt
     2221 gagatatagc tttgatgacg tttagaataa agcaaagaat catctgtaca agaaggtata
     2281 gtccaaacat tttcaaaacg ttctttagta ttaaaagcaa tgtctttgct tggctgatgt
     2341 gataaggcca ttagataatc tggtaggcat aaaaaactgt aattgatagt tccttgcttt
     2401 tgatgtgaga gatggttatc aaaaacaggg tcaccccaag tgacatcaac gccataataa
     2461 gtgttattaa tttgaacagc attccatgca tgtgcaaaag attgctgagg ttgctgagat
     2521 gtaccagttc cacggatata ggcgactgga atgccagctt tttgacaaag aaactgaaag
     2581 gcttgggcat agccattaca aacagataaa tgatcaataa aaacactttt aatgtcttga
     2641 ttagaagcga cctgggattg actgcctgat tgataggctt caaaggcttt tttattgtag
     2701 tctgtgtctc gaatgatgac ctcataaaaa tatttgacct gctcatagcg atcctttgat
     2761 ggcgtgtttg cgacgatatc attaccgatt gcttgcaagt cttgataaac gttcttggca
     2821 tcttctggga taggaaaggt gacaaagacc gtttgatcag aaaactcaaa tcgataatcg
     2881 gcagatgtaa tccagtaaaa ttcgggatta tccatcacaa aggcgtcaat cgttttaatt
     2941 aagctttttt tagaaaccgg cgtcaaactg atgatttcac gaaactgtgc tagactatcg
     3001 tataaagtga ggtaattttc ttgttcggtt ttggataatt gttggaaata ataccgttgt
     3061 cttacttgtt tgacgatttg ttggcgcttt tttccggtta aagaaaaaac agaatcggta
     3121 ttagaaggtt tgctagtgtt gtgacacgca gacataccaa ctgtcataag gccaattact
     3181 gttaagattt taatcttttg tttcatcata actcccattc taatctaata atcttattat
     3241 aacatagaga atagctggaa tggggagagg gaaagatttt caaaaagcaa aatcgtgttt
     3301 ggaaagggtc atgatttttc taggtattca gtccatcttg tcccaaaatg aagctatgct
     3361 cacttgaaag tgattttact tagttggaaa acttgcaaac tgtccgtaat atgatataat
     3421 aataggcgga gcaacacttg tgcgtgaagt gggtcagggg aggaatccag cagccctaag
     3481 cgattttcgg gtgtgtgctc tttttttgtt gactttacta aagtaatctc ttccttctat
     3541 agtgtcatca gttgttgaaa ccgattgata tttttattta ggttaagagg tataaaacag
     3601 gacataaaaa gttttaaatg aaaacaaaca ttttgacaat tatcatatta tcatgtgttt
     3661 ttagctatgg aagtcaatta gcttatgcag atgaaaattt aaaagattta aaaagaagtt
     3721 taaggtttgc ctataatatt accccatgcg attatgaaaa tgt
//
LOCUS       DAUGUF010000069         3702 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUGUF010000069 DAUGUF010000000
VERSION     DAUGUF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3702
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.069"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            20..1207
                     /gene="hasA"
                     /locus_tag="VIB71_001671"
     CDS             20..1207
                     /gene="hasA"
                     /locus_tag="VIB71_001671"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HEQ8823386.1"
                     /translation="MYLFGTSTVGIYGVILITYLVIKLGLSFLYEPFKGKPHDYKVAA
                     VIPSYNEDAESLLETLKSVLAQTYPLSEIYIVDDGSSNTDAIQLIEEYVNREVDICRN
                     VIVHRSLVNKGKRHAQAWAFERSDADVFLTVDSDTYIYPNALEELLKSFNDETVYAAT
                     GHLNARNRQTNLLTRLTDIRYDNAFGVERAAQSLTGNILVCSGPLSIYRREVIIPNLE
                     RYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQSTARCDTDVPFQLKSYLKQQNRWNK
                     SFFRESIISVKKILSNPIVALWTIFEVVMFMMLIVAIGNLLFNQAIQLDLIKLFAFLS
                     IIFIVALCRNVHYMIKHPASFLLSPLYGILHLFVLQPLKLYSLCTIKNTEWGTRKKVT
                     IFK"
     gene            1243..2451
                     /gene="hasB"
                     /locus_tag="VIB71_001672"
     CDS             1243..2451
                     /gene="hasB"
                     /locus_tag="VIB71_001672"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEQ8823387.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLSSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2633..3547
                     /gene="hasC"
                     /locus_tag="VIB71_001673"
     CDS             2633..3547
                     /gene="hasC"
                     /locus_tag="VIB71_001673"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEQ8823388.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     GILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
BASE COUNT         1269 a          622 c          652 g         1159 t
ORIGIN      
        1 tatcttgatt tatctaaata tgtatctatt tggaacatca actgtaggaa tttatggagt
       61 aatattaata acctatctag ttattaaact tggattatct ttcctttatg agccatttaa
      121 aggaaagcca catgactata aagttgctgc tgtaattcct tcttataatg aagatgccga
      181 gtcattatta gaaactctta aaagtgtgtt agcacagacc tatccgttat cagaaattta
      241 tattgttgat gatgggagtt caaacacaga tgcaatacaa ttaattgaag agtatgtaaa
      301 tagagaagtg gatatttgtc gaaacgttat cgttcaccgt tcccttgtca ataaaggaaa
      361 acgccatgct caagcgtggg catttgaaag atctgacgct gacgtttttt taaccgtaga
      421 ttcagatact tatatctatc caaatgcctt agaagaactc ctaaaaagct tcaatgatga
      481 gacagtttat gctgcaacag gacatttgaa tgctagaaac agacaaacta atctattaac
      541 gcgacttaca gatatccgtt acgataatgc ctttggggtg gagcgtgctg ctcaatcatt
      601 aacaggtaat attttagttt gctcaggacc attgagtatt tatcgacgtg aagtgattat
      661 tcctaactta gagcgctata aaaatcaaac attcctaggt ttacctgtta gcattgggga
      721 tgatcgatgt ttaacaaatt atgctattga tttaggacgc actgtctacc aatcaacagc
      781 tagatgtgat actgatgtac ctttccaatt aaaaagttat ttaaagcaac aaaatcgatg
      841 gaataaatct ttttttagag aatctattat ttctgttaaa aaaattcttt ctaatcccat
      901 cgttgcctta tggactattt tcgaagtcgt tatgtttatg atgttgattg tcgcaattgg
      961 gaatcttttg tttaatcaag ctattcaatt agaccttatt aaactttttg cctttttatc
     1021 catcatcttt atcgttgctt tatgtcgtaa tgttcattat atgatcaaac atcctgctag
     1081 ttttttgtta tctcctctgt atggaatatt acacttgttt gtcttacagc ccctaaaact
     1141 ttattcttta tgcaccatta aaaatacgga atggggaaca cgtaaaaagg tcactatttt
     1201 taaataatat gtgcatcgag tagttagaga aggagtaatt ttatgaaaat agcagttgct
     1261 ggatcaggat atgttggatt atcactagga gttcttttat cacttcaaaa cgaagtcact
     1321 attgttgata ttcttccctc taaagttgat aagattaata atggcttatc accaattcaa
     1381 gatgaatata ttgaatatta cttaaaaagt aagcaattat ctattaaagc aactttagat
     1441 agcaaagcag cttataaaga agcggaactg gtcattattg ccacacctac aaattacaac
     1501 agtagaatta attattttga tacacagcat gttgaaacag ttatcaaaga ggtactaagc
     1561 gttaatagcc atgcaactct tatcatcaaa tcaacaattc caataggttt cattactgaa
     1621 atgagacaga aattccaaac tgatcgtatt atcttcagcc ctgaattttt aagagaatct
     1681 aaagctttat atgacaactt atatccaagc cgaattattg tttcttgtga agaaaacgat
     1741 tctccaaaag taaaggcaga cgcagaaaaa tttgcacttt tattaaagtc tgcagctaaa
     1801 aaaaataatg taccagtact tattatggga gcttcagaag ctgaagcagt aaaactattt
     1861 gccaatactt atttagcgtt aagggtagct tattttaatg agttagacac ttacgcagaa
     1921 tcgagaaaat taagtagtca catgattatt caaggaattt cttatgatga tcgaatagga
     1981 atgcattata ataacccatc atttggttat ggaggttatt gtctacctaa agatacgaag
     2041 caattattgg caaattacaa taatattcct caaacgctaa ttgaagctat cgtttcatca
     2101 aataatgtgc gcaagtccta tattgctaag caaattatca acgtcttaga agagcgggag
     2161 tccccagtaa aagtagtcgg ggtttaccgt ttaattatga aaagtaactc agataatttt
     2221 agagaaagtg ctatcaaaga tgttattgac attcttaaaa gtaaagacat taagataatt
     2281 atttatgagc caatgttaaa caaacttgaa tctgaagatc aatctgtact tgtaaatgat
     2341 ttagagaatt tcaagaaaca agcaaatatt atcgtaacta atcgctatga taatgaatta
     2401 caagatgtta aaaataaagt ttacagtaga gatattttta atagagacta gccatgtctt
     2461 catctataac aataatattc atttttactt taaaagaact gcagttggtg gtatgattga
     2521 gcactatgaa atagtcgaaa aatcatatga aaacgtaaca tgatgtcaaa tgaattccgt
     2581 tctgaaaacg aatgtcacta agccatagat tataaaaagt gaggagttac tgatgaccaa
     2641 agtcagaaaa gccattattc ctgctgcagg tctaggaaca cgttttttac ctgctaccaa
     2701 agctcttgcc aaagagatgt tgcccatcgt tgataaacca accatccagt ttatcgtcga
     2761 agaagcgcta aaatctggca tcgaggaaat ccttgtggtg accggaaaag ctaaacgctc
     2821 tatcgaggac cattttgatt caaactttga attagaatac aacctccaag ctaaggggaa
     2881 aaatgaactg ttgaaattag tggatgaaac cactgccatt aaccttcatt ttatccgtca
     2941 aagccaccca agagggctgg gagatgctgt cttacaagcc aaagcctttg tgggcaatga
     3001 accctttgtg gtcatgcttg gagatgactt aatggacatt acaaatgcat ccgctaaacc
     3061 tctcaccaaa caactcatgg aggactatga caagacgcat gcatccacta tcgctgtgat
     3121 gaaagttcct catgaagatg tgtctagcta tggggttatc gctcctcaag gcaaggctgt
     3181 caagggcctt tacagtgtag acacctttgt tgaaaaacca caaccagaag atgcgcctag
     3241 tgatttggct attattggtc gttacctcct aacccctgaa atttttggta ttttggaaag
     3301 acagacccct ggagcaggta acgaagtgca actcacagat gctatcgata ccctcaataa
     3361 aactcagcgt gtctttgcac gagaatttaa aggcaatcgt tacgatgttg gggataaatt
     3421 tggattcatg aaaacatcta tcgactatgc cttagaacac ccacaggtca aagaggactt
     3481 gaaaaattac attatcaaac taggaaaagc tttggaaaaa agtaaagtac caacacattc
     3541 aaagtaatgt gttggtactt tacttttttc cttgtttata gcaacttaag tttatatctt
     3601 gaaaattgtc aacgttccaa aatataaaag ttttgtgtta tacaacttta ctagagggac
     3661 atattaataa taggatttat acgtagaaaa atgataaaca ta
//
LOCUS       DAUGUF010000070         3257 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUGUF010000070 DAUGUF010000000
VERSION     DAUGUF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3257
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.070"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..492)
                     /locus_tag="VIB71_001674"
     CDS             complement(<1..492)
                     /locus_tag="VIB71_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEQ8823389.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFI"
     gene            complement(655..2187)
                     /locus_tag="VIB71_001675"
     CDS             complement(655..2187)
                     /locus_tag="VIB71_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEQ8823390.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVIVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            complement(2365..3096)
                     /gene="aphA"
                     /locus_tag="VIB71_001676"
     CDS             complement(2365..3096)
                     /gene="aphA"
                     /locus_tag="VIB71_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEQ8823391.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
BASE COUNT         1129 a          647 c          493 g          988 t
ORIGIN      
        1 aataaattct atagttggaa tcattgctaa atctttatta atagcatcaa tcatagcatt
       61 tgttcttatt ttgacagtct tctgatatcg gggattgttg gaaactggta ataaagataa
      121 gagataaatc tgactgtaga cacaatgact acgaatctgg ctaataagct ctacaatagt
      181 cttgacaata tgacatttat catatccaag cccgatatca ttacaaccaa ttaataaaaa
      241 aatatgttta ggctctaaat cagtaatttg gacagaaaaa tggcgcaata accactgact
      301 atctatccca gcaatacctc gattaataat aggcaaacat gaaccaaaag ctttttttaa
      361 aggaaaaaat tcaatgagag aatcacctgc aaatacaatg cctccttttg gggctaactg
      421 atttttgtta cggtactcaa tcaatttttg ttcttgatag tgacgtagct cttctgaaac
      481 aatttctaac atctcagcct ccttagctta tctttattgt tagtataaca aaaagcctac
      541 ttgacttcat caaaagcgtt tcactttggt tcagatgaaa ctctagcagt aaaacgttcg
      601 aagacttagt ctaaaagaca agctcgaact ttccgaattg tgataaatta atacctacat
      661 caatacctca cggacaaaac ctgtatcagc ttcattaacg accaaaaaga tagttgctcc
      721 tgataaaagg cgcgtgttac ctgacacaac ttgagatttt tgatggtgaa tttgggttgt
      781 aattaagaca ttttctggaa gctttaactc tttaacatat ttccctgcaa tcttatcacc
      841 aacagtcaat tcaattaatg ttggttcaac aagattagtt ggatgcttca ttgccatctt
      901 atctagcata gcttcataaa ttggctgtcc atttaacaaa tccattacta aataggagac
      961 aaaagtaact acagctatgg ccattaaggg tttcaaatca cctaccattt cagttaccaa
     1021 aatcatgcct gtcagtggtg cttttgaaat tgccgcaaaa taccctgcca tccctaatat
     1081 caaaaaaaga gaaagaaaag attggttcaa taaacctaat tgagaagcta tttgcccaaa
     1141 taataggcct gccaaagcac ctaaagttaa aataggtaaa aaaatacctc caggtaagcc
     1201 acttccataa ctaaacatac taacaataaa tcgaataata aaataaaaga agatagtcat
     1261 caaaggcaat tgttgattgg ataaagaaag tattaaacca tgtcctcctc caagtaactg
     1321 tggtaaataa tagccaatcg gtaaaattag aaaaaccata ataataccgt aaaaataagc
     1381 tggcagatgt aaccaactcc ctaaaataac ataaagttta ttaaaattaa ggataactat
     1441 ctcatataaa tagcctaagc agcctagaaa taatccaagt aaaagcaaca accaatattg
     1501 attgagtcct aaaaaaggca tcgcctctga cattgctaag actggtttca atccaaaaat
     1561 attcagagaa ataaaattag ccactaagct agccactagc gctgtaatcc aaattaaacg
     1621 cgaaaaatga tggtaaattt cttcaacaac aaacaagagg cctgctattg gagcattaaa
     1681 agctgctgat agccctgctg ctgctccgct ggcaattagc actcgctttt ccaaacgact
     1741 cgattttaaa aacttagcta atcctttggc tgacatagca cctaactgaa tcgaaggacc
     1801 ctcacgaccg agcataaatc ccatagaaat agccatgatt cctcctaaaa attttttcca
     1861 aaggacactc caccaatctg gggacattag tccctttagt tctccttcga catgggggat
     1921 ccctgatcct tttatatcag aatcagactt tactaaaaaa cctacaaaaa ggacagctaa
     1981 taaactgaca cttagtatag gaagtagcaa cagcgaattg atatgagcgt atcggtacca
     2041 ttcaatcacc cagtcagctg tcacttcaat taacaaccgg aataaactaa caataacacc
     2101 agcaataata ccaactataa caccacgcca aacataggca ataattgatt tgttggaaaa
     2161 ggtgaattca tttttatggt tttccatgtt gtcctctctt tcttttaaat acactgttac
     2221 cattgtatca aagacaacct taagttacca gtgattcttt tttagaactg atttctgtaa
     2281 cccaaaaaac ccactgggct attggttact cagtggggtg atgaaagaaa ttaccgttac
     2341 ttcctttctt acacaaatat ttgactaata agccgaattt tctaaaacct cttctccgta
     2401 tcctccagct tttggcaaag gaagattggt tgaattagga gctcttaaaa tgcgaatagg
     2461 tcttgcacct gcctctttgg cagcatttat atcttcatca ctatctccgt aatgaatttg
     2521 tgagccgttt ttctttatat aatatgtttt atcatactga tacggcttca cagctttatc
     2581 tcctgtataa ttgatagcta ttggcttgtc taacttaaaa tctttagcca gtgacttagc
     2641 tgttttatca atctcacctt ttttatacat cgatcctcga gttcggccag taataaagac
     2701 aattttatct cctcgttttt gatgcattgc gattagttgc tttgcatact cttttggaat
     2761 agaatcctga tctccccgtt tagcgaccaa gtcccaaaat ttttgcttat gcaaaaaatc
     2821 aaatgagcct ggagttatat attctttgcc gtactgaaaa tattggctag taaataacaa
     2881 agtatcatcg atatcaaaac taaccgttat aggtttttgt ccttctaaac tgctcgcgat
     2941 atcagcaata gaaatcaatt ttactgttgc ctgatttgaa atggccgtta taccttcttg
     3001 tgtataagga actttagggc cactagcttc gacaggcaat gctatgattc cacaaaaact
     3061 aactgtaaac aggatactgg taaattcttt tttcatctaa aaacctcctt aatcattatt
     3121 gtacaaaaat acacgattta agtaaagcgg tttcaaattc ttataatagt accctttaag
     3181 ttctgaataa ggatgaagtt attcaacaaa gatgatctaa aaaattatca taatcgattt
     3241 aaaaaatatt gaaaacc
//
LOCUS       DAUGUF010000071         3197 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUGUF010000071 DAUGUF010000000
VERSION     DAUGUF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3197
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.071"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            37..1899
                     /gene="cadA"
                     /locus_tag="VIB71_001677"
     CDS             37..1899
                     /gene="cadA"
                     /locus_tag="VIB71_001677"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEQ8823392.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVFSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAEAASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(2199..3134)
                     /locus_tag="VIB71_001678"
     CDS             complement(2199..3134)
                     /locus_tag="VIB71_001678"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEQ8823393.1"
                     /translation="MVSTATQISHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
BASE COUNT          959 a          584 c          680 g          974 t
ORIGIN      
        1 aagattgaat aacttttaat tgcgagggaa ctaaaaatga caatcagaca atggatggca
       61 gaccatcttc atttaatgga gactttagcg tgtttggtat taataataat tggcctagcc
      121 tttttacact catttccaca agtggcttcc gctattttca ttacagcctt cttgattgga
      181 ggatatgcgt ctgcaaaaac gggtatattg gatttggtga agaacaaaca cttgtcagtg
      241 gatattttga tgattttggc agctatcggt gctggaatta tcggctattg gctggagggt
      301 gctctgctta tttttatctt ttcgttgtcc aatacgcttg aagaaatggc catggaaaaa
      361 agtaaggatg ctatttcagc cttgatgtcc ttgacgccag atacagctcg tcaataccaa
      421 gaagatggcc atattttaga agttgagacc agatccttga gtgttggtga ccgtttacaa
      481 gttcgtaaag gcgaagctgt tccaattgac gggcagttgc ttagtccttt tggtcaattt
      541 gatgaatcta tggtcactgg tgagcctatc actgttgata aggcagaagg ccaggatctg
      601 attgggggaa ccattaacca aggacaaacc atagatatgt tggttactat tgaaaatgac
      661 gatactctct ttgccaagat tattaatctg gtggaatctg cccaagaaaa gaaaagcaaa
      721 accgccacct ttatcgaaag cttagaagat ggttatgtca aatttgtgct cgtccttatt
      781 cctgccttta tcctctttag ccactttgtg ttttcttgga cttggttggc tgctttttac
      841 cgagggatga ttctcttaac agtagcttca ccatgtgccc taattgccag ttccacacct
      901 gctagcttgg ctgctatttc tcgtgcagcc agaaagggat tgattatcaa aggaggggat
      961 attgtcgata acatgggaga tattaaggct gttgtcatgg ataaaacggg aacgctcacc
     1021 caaggaaaac cttctgttgt gaatgctcat tatttggaag atgagttgct cgtgaataga
     1081 ctggtaaaag gagcagaggc tgctagtacc catcctattt ctaaagccct tcttgaatac
     1141 actgaaaaat tggagccact gacctttgac cacttagaag aaatttctgg gaaaggtttt
     1201 cagggcttct atcaagggca agaatggcga attggcaaga aaaccttcat tttggaaaag
     1261 gttcaagacc tatcagcttt tgaagaaact attcaagtgg aagaaaatca agggaaaacc
     1321 ctaatctttg tttcacgtga ccatcaattg atagcttact atgccctctt ggatgatatc
     1381 aaaatagaat caaaacgtgc tattaagtct cttcatgcca tgggaatcaa aacagtcatg
     1441 ttaacaggtg accaagaacg aaccgccaat tatgtggcac aaaaacttgg tattgatgaa
     1501 gtggtagcca actgtatgcc tcaagataag gtggctaagt tagcagaatt aaagaccaaa
     1561 tatggttttg tggccatggt aggagatggt attaatgatg ctcctgccct tgctcaagca
     1621 gatgtttctt atgctattgg atcaggaaca gatattgcaa tggaaagtgc agacagtgtg
     1681 attatggatg acttgactcg tattccattt tcgattcaac tttcccgcaa aatgaagacc
     1741 attatcaaac aaaatattgt ttttgcctta tctgtgatta ccttattgat tttagccaat
     1801 gtttttcagg tagttaactt gccgcttggt gttgttggac acgaaggctc aacgatttta
     1861 gtgattttaa atggcttgcg tttactttct tttaaataat ttagaaactt gcttgaaaac
     1921 ttgaaagtgt ttataataat agtaagactt atgaaagaga aaaccgccgt atgtttacta
     1981 ttatgatcat tggtttagct gtattttcaa taattaaaat cattctattt ttctattttt
     2041 atcagcaatt tgagcgcaag caaaaaagaa aagttgaatc aaacaaccag caaagacagt
     2101 cccaagaaag tgacgctgtc ccttcaaaaa aattcccatt ttaaaaagct tggaaagtgt
     2161 acaaagtgca catttccaag cttttttgac tattaaggtt aatctttgta acgtaagttc
     2221 ccacgaaaat cgtctaagct ttggtagcct ttttctacca taatcgtttt tagttcctta
     2281 gtgacccgtt caaagatagc tggcccttct tgatgaaggg ctgtcccaat ttggaccatg
     2341 ctggcgccac aaagaatatg ttcaaaggca tcgcgtcctg ttttaactcc ccctgtacca
     2401 ataatgtgga tagaaggttt taagcgtttg taaaacgcat ggacattggc tagagcagta
     2461 ggtttgatgt aatctccacc tataccacca aagccatttt taggcttgat gaggacttgt
     2521 tcatcctcaa tgaccagccc atttccgata gaattgacac agttaacaaa ggaaaggggg
     2581 tatttattga aaatcgcagc cgcttgatca aaatgcacaa tgtcaaaata aggaggtaat
     2641 ttgataccaa gaggtttagt gtaataggta aagatgttct ctagaagttg atcagtggtt
     2701 tcaaaatcat aagcaatctg tggttttcct ggaacgttag ggcaagaaag gtttagttcc
     2761 actagaccct cataatctga agccatgatg gcttttaaaa tggtttcggt ttcagtagga
     2821 gatagcccga caacggagag aaagtgaggt ttatgttgcc cggttttggc aagatcactg
     2881 acaaagtcta agtagtagcg aaaaccatta ttagggagtc ccattgaatt gatagaacca
     2941 agacgagtat ctgcgtagcg aggttctgga ttacctggac gaacttcaag cgtccctgtt
     3001 ttggtgacaa aggaagcggc ttgagacttt tcaacctcca taagctcttc ttttgtcatg
     3061 cagtaaacac cagcagcatt catcaaacag ttatcaaaag agaaatgact aatttgtgta
     3121 gcagtagaaa ccattatttc ctccatattt tagacaaatt ttttctattc taccactagg
     3181 catgaataat agcaagc
//
LOCUS       DAUGUF010000072         3047 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUGUF010000072 DAUGUF010000000
VERSION     DAUGUF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3047
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.072"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..854
                     /locus_tag="VIB71_001679"
     CDS             <1..854
                     /locus_tag="VIB71_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ8823394.1"
                     /translation="ITWIISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTI
                     QYIGGDGKLTETIANYSQQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLAS
                     KEDLCRQGNTLVDTYTGKYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFI
                     LRLPFAGTIGVLVAFTALIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEG
                     NFIYPKVVGGSIGLPAMWVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQA
                     IQKKQVS"
     gene            903..1583
                     /gene="radC"
                     /locus_tag="VIB71_001680"
     CDS             903..1583
                     /gene="radC"
                     /locus_tag="VIB71_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEQ8823395.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(1585..2280)
                     /locus_tag="VIB71_001681"
     CDS             complement(1585..2280)
                     /locus_tag="VIB71_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEQ8823396.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(2290..2934)
                     /locus_tag="VIB71_001682"
     CDS             complement(2290..2934)
                     /locus_tag="VIB71_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEQ8823397.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEVGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT          980 a          495 c          567 g         1005 t
ORIGIN      
        1 taattacttg gattatttcc attgtcattc cagacttaat tacaagtatt agtactctaa
       61 caaaatttga tactataacg atacaagaag ttgttaacaa tcttgagcac aataaactgt
      121 tagcacgtac tattcagtat attggtggcg atggcaaact tacagagacg attgctaact
      181 atagtcaaca gttattaaag caatttctta ctgttttgac aaatatttta acatctgtca
      241 cggttattgc ttctgcaatt attaatcttt ttattagttt tgttttttcg ttatacgttt
      301 tagcaagtaa agaagatctt tgtcgtcagg gaaatacttt agtagatact tatactggta
      361 agtacgctaa acgcattcat tacttgttag agttgttgca tcagcgtttt cacggatttt
      421 ttgttagtca gaccttagaa gctatgattt taggttcgct gactgctagt ggcatgttta
      481 tattaagatt accatttgca gggactattg gcgttttagt agcttttaca gcattgattc
      541 cagttatagg tgcttcaatt ggagcagcta ttggatttat tttaattatg actcagtcca
      601 tgtcacaggc cattattttt atcatttttt taattatttt gcagcagatt gaaggcaatt
      661 ttatttatcc gaaagtagtt ggtggatcga ttggattacc ggctatgtgg gtattaatgg
      721 caattacaat aggcgcttct ttaaagggaa tagttggtat gattattgca gttcctttag
      781 cagcgacact ttatcaagtg attaaagata atattcaaaa aagacaagct attcaaaaaa
      841 aacaagtttc ctaaaaggaa cttgtttttt tgtcgaataa aaagatggag gtaatatgat
      901 aaatgtattc tataaaatgt gatgataata aagccatgcc aagagaacgt ttgatgcgac
      961 taggagcaga gtctctaagt aatcaagaat tattagcaat tttattacga acaggtaata
     1021 aagaaaagca tgtcttagag ctgtcatcct atcttttatc gcatttagac agtctggcag
     1081 attttaaaaa gatgtctttg caagaattac aacatttggc aggtatagga aaagttaaag
     1141 cgattgaaat taaagctatg attgagttgg tttcccgaat tttagcgaca gataagacat
     1201 taactgatag cgtattaacc agtgttcagg tcgctgaaaa aatgatggca gctttaggag
     1261 ataaaaaaca agagcattta gtcgtattgt atttagataa tcaaaatcgt attattgaag
     1321 aaaaaactat ttttattggg actgtccgac gttcacttgc agaaccaaga gaaattttat
     1381 actatgcctg taaaaatatg gcgactagtc tcattgttat tcataatcat ccttcaggaa
     1441 atattgaacc tagttctaac gattattgct ttactgaaaa aataaaacga tcatgtgaag
     1501 atttaggcat tatctgtcta gatcacatta tcgttagcta taaagattat tatagttttc
     1561 gagaaaaatc aacccttttt taaatcagaa gtcattgacg aataagcgga acaattgtag
     1621 atcttcatct cgaacacctt ggagaagttc aggatgccac tgaacaccta aaaaaggaat
     1681 ggcatcgttg gttgatatga ctgcttcgat ggtaccatca cgtggatctc tagcgattac
     1741 ttttaaatcc ttagcaacag tttttaaact ttggcgatga aaagaattaa ttaatgtctt
     1801 atgaccgtaa ataggatata agatagagtc tggctcaata atcatttcgt gtgataagaa
     1861 atcagaaggc gcttcttgcc aatgtgagtc aatgtgttgg ttaagatttc ctcctaaggc
     1921 aacattcatt aactgtgtac cacgacaaat ccctaagatt ggttttttta atgttatagc
     1981 ctccttgatg atagctagct caaatgtgtc tcgctctggt gaaaaatcat catcaaaagc
     2041 agccttctct tcttgataat attttgggtc aacgttttgc ccaccaatta aaatgatttt
     2101 atcaaccata gatacataag ttttagcggc ggcttcatca ccaatgggta aaagaagcgg
     2161 cagcccccca gattgagtga ctgcctgtac aaatccagta ggtgcatatg accatgggag
     2221 attatccaaa gccatattta gtctttgatt tgcagttatt ccaataatcg gtttggtcat
     2281 tatacctcct taatctagat gattttgatt cataaaatag agtagtgtct ggagctcact
     2341 ggtcaaatcg acagattgaa caataactcc tttaggaact tgtaggtgaa caggagcaaa
     2401 actcaagatt cctttgattc ctacttcaat aagttgatca gtaacttctt gagcatgaat
     2461 gctgggaacc gttaagatag ccgtttcaat gtcagtgttt gcaatccgtt ctttgacgga
     2521 tgagatacca tggactggaa tattatcagc tgttttagta ccaacaagag cgttatcatc
     2581 ggtatcaaaa cccatggcaa tttgcatctt attacgatca tggaagcggt aatgtaatag
     2641 agcacgccct atattaccgc atccaactaa gataacgttt gttgtagagt gatcattaag
     2701 caagtcagca aaaaaattca tcaatttggt aacatcatag ccaaacccac gacgccccaa
     2761 ttctccaaaa taagaaaagt cacggcgtac agtagcagag tcaattccca ttgcatctgc
     2821 aatttgttta gaactggctt tttcaacttg gtcagcatgg aatcgtttaa aaatacggta
     2881 ataaagtgat aagcgctttg cagtcgcttt tggaatagat ttgtcaataa ccactatttt
     2941 actccttgta gatttctcgt taaatatgtc tgtctttatt gtaacaaaaa gattgtgaaa
     3001 aatgcaacat tttgattgtt tttgtatgag ttaaaaaagc taaaatt
//
LOCUS       DAUGUF010000073         2906 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUGUF010000073 DAUGUF010000000
VERSION     DAUGUF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2906
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.073"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(144..1454)
                     /locus_tag="VIB71_001683"
     CDS             complement(144..1454)
                     /locus_tag="VIB71_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEQ8823398.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KALLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPDALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHSLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPILS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            1678..2550
                     /locus_tag="VIB71_001684"
     CDS             1678..2550
                     /locus_tag="VIB71_001684"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEQ8823399.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYISSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          883 a          508 c          675 g          840 t
ORIGIN      
        1 ctcttcctca aggatgagtt ttacagcaga gagtttgaag gctttatcaa aggtttttct
       61 tggcataatg acttttcctc gtttccactt aattttgtgt ctactttatt ataccaagtc
      121 caaccttaag ttagacaata aatctaactt aaggaagcta gcagcatgag aatccagatg
      181 gtcaagagtg ccaaacttaa gctgatgggc acacccagaa gaatttgttt tttgaaagca
      241 agactgcgtt cctctatatg gggaagggag agttgaatga gggaaccagc tgatgaaaaa
      301 ggagagatat tagtagatag agcgccaata atagtggctg ttgtgagtaa gcgaatatca
      361 atgtgaggac tttgagcact gatggtagca atgatgggaa agagagttgg ggctacaacg
      421 gatagggtgg aactaaagag tgacatcact ccggctatca cacaaaagaa cagaggtaac
      481 cagaaatgag gaatggttgt tgttatgagg tgccctatca gtgtaactaa acctgacttg
      541 accgctagag acattagtaa gctcatgccg cagagcatga taattatagc ccagggaacc
      601 ttagccaaaa tggcttcttg cttccctaat ttgagcctta aggcgaggca gaccatgagt
      661 attgagacaa agccaatatc aaatgtttgt cgataagtag ctatccatgc gatgtttggg
      721 aaaatgagat gcaacaaggg aaaaagccaa accaaaacca tgctgctgat catgagcaag
      781 gtggtttgtc tttggacctt gctgaggatt ggtggttggt caatagtcaa ggatgagttt
      841 gttcttccct tactgtagcg gatgtaacaa gataataaaa gcaagacgat gagtgggtag
      901 ataatgctga cgataaagat atgattgcca agtgaaaaag cttgctcttc ccatcccatt
      961 tgcttaaaca ggccttgaaa gacaatgcct gagccactgg ttatcaaatt agcccctcct
     1021 gaagctcccc aattgacggc ttgagctcca atcaaagagt gtttgtccgc tttttgacag
     1081 agggtaatcg ctagaggaca gcaaacggcc atagtagtga aaaatccagc acctaaagca
     1141 gacaaaaggg ttgctatcag gtataaaatc atgtagaggg cgtcagggtg ggtgcgtgtg
     1201 cggtagagaa tgtgttgagc caaaacatca agagtgccgt tagttgttgc aacgttataa
     1261 aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg gccaaaaatg aagaagtgct
     1321 ttggggctta atcccatgag agtggttgcg atgaggtaag aaaaagcaat agccagcagg
     1381 ccaatattga ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc gctaattatt
     1441 attaaatgaa tcattgaatt gtcctttagt tagaatatga aaataggttg gcaattttgg
     1501 cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa aaaattacaa
     1561 ttgtcttgac acttgttggg atttaaaatg aggtattcag gtttgtgatt tcctacggaa
     1621 gttaatagca attgcctcta gtgcttacaa gtgatattaa aaatagagga cttagtgatg
     1681 tcaatcattt caactgattt aacccctttt caaatagatg atacattgaa agcagccttg
     1741 cgagaagatg ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa
     1801 gccaaggtgt cgctttttgc caaggaagct ggtgttttag cggggctaac cgtttttcaa
     1861 agggttttta ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat
     1921 ggggatcgtt tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagcctc
     1981 ttaacatgtg aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg
     2041 acagctgctt atgtagaagc cttaggcgat gatcgcatta aggtatttga tactcgaaaa
     2101 accactccta atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat
     2161 catcgcttta atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt
     2221 agtgttcaaa aggcgattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag
     2281 gtggaagtgg aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgt tgatattatc
     2341 atgttggata atatgtcatt ggaacagatt gaacaggcca ttactctaat tgcaggacgt
     2401 tctcggattg aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta
     2461 gcgattgatt acatctccag tggtagttta acccatagtg ctaagagtct cgatttttcc
     2521 atgaagggtt taacctacct tgatgtctaa gttgcaaaat aaactaactt tttaaagaat
     2581 gtctttcctc tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatactttcc
     2641 ctgttttcac ctgattcgtg tccgcttatt ataccaattc caagcattca cctgaaaaaa
     2701 cgatagggag aggttagtgt ttttattgta aaagttccac gccaaatcca tgaagaaaag
     2761 tttgttttca gaaatcacga ttcatcataa taaaatcaat caaagtcgtt aactaggagt
     2821 gtactgaccc caaaaagttg gacaaataat tattgaaagg atttagttct gtattggaca
     2881 ggactaaatc cttttagttt tgcttt
//
LOCUS       DAUGUF010000074         2898 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUGUF010000074 DAUGUF010000000
VERSION     DAUGUF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2898
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.074"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..1483
                     /locus_tag="VIB71_001685"
     CDS             <1..1483
                     /locus_tag="VIB71_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEQ8823400.1"
                     /translation="YSEFENQLFETIMFLSMKTLVLDINHFSKEIENKSEAYEQCIQQ
                     IREENGINHFFDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIRSCFNISEPLSN
                     VAFSLGDSHSKKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNIPSFSLPKS
                     LVKADYCWQLGVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDLHMENVIVSGGDLYL
                     IDVETFFQRKLNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNSAPNVSGISGKG
                     GKRKKGKYELINKNRGDMKLVKTDYFQEDGYNIPTLNGKVVEPLDYANEVIAGFRECY
                     TFLMSQRAKVKKILEDFPKLKTRAIFRNTSDYGKFLQASTNPKYLFSEKKRENLFSIL
                     HESKHIEQFIVVSEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGNLGDTTSLFDSITTL
                     NDERLKFTCELLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            1485..2018
                     /locus_tag="VIB71_001686"
     CDS             1485..2018
                     /locus_tag="VIB71_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823401.1"
                     /translation="MDKTDFRNISAFVSQDSPIFDGDVMYNISLGRESVSGEQVIETC
                     KRVSLYEDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRVLVTHRLNTVEKADKILIMDNGKIIDYGSHHCLYKNNEYY
                     RDLYDSYMNNYQEEEIK"
     gene            2015..2752
                     /locus_tag="VIB71_001687"
     CDS             2015..2752
                     /locus_tag="VIB71_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ8823402.1"
                     /translation="MNQLLLKNVCKRYPNQPNYALDHINLTVRKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISAFSDNEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNVDSSKINDLINNYAKRFNLYEQLEKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEGTMRILSEINKTEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHMEIDKEDCGETFYDVISQALSDRGE"
BASE COUNT         1041 a          381 c          541 g          935 t
ORIGIN      
        1 ttatagtgag tttgaaaatc agttatttga aacgatcatg ttcctttcga tgaaaacact
       61 agttttagat ataaatcatt tttccaagga aattgaaaat aagtcagagg catatgagca
      121 gtgtatacag cagataagag aagaaaacgg aataaatcat ttttttgaca ggtatccgta
      181 tttgctaaaa caaattaata aagaagtagg actgatagag gaatcatatt ctttattatt
      241 tgatagattt ttagaagact tatctgagat aaggtcgtgc tttaacatta gtgagcccct
      301 aagcaatgtt gccttttcac ttggtgacag tcactctaaa aagcaaacag ttgttaaaat
      361 tgcgtttaaa gagaaatctg tttactacaa gcctaaaagt tatcattcac acagtatctt
      421 gttagaactt actagtttat tgaaatctag taatatacct tcattcagtc ttcctaaaag
      481 cttagttaaa gcagattatt gttggcaact tggtgtagct tatacaagtt ccaataaaga
      541 tgaagtagcg aaaatttact ttaagtatgg tgttttagca gcattttctg aaatattttc
      601 tattacggac ttacatatgg aaaatgtgat tgtttcaggc ggagatttat atttaattga
      661 cgttgaaaca ttttttcaaa gaaagttgaa tgtacaaaat cagaattttg aagggattac
      721 tgtagacacc tatcagagaa tttatgagac atcactttca aacggtttat ttcctgtaca
      781 atttgagaaa aacagcgctc ctaacgtttc tggaataagt ggaaaaggtg gaaaaagaaa
      841 aaagggaaag tatgaactga taaataaaaa tcgtggagat atgaagttag tgaaaactga
      901 ctattttcag gaagatggtt ataatattcc gacattaaat gggaaagtgg tggaacctct
      961 cgactatgct aatgaggtaa ttgcaggttt tagagaatgc tatacatttc tcatgtcgca
     1021 acgtgcaaag gttaaaaaaa ttttagaaga tttcccaaaa ttgaaaacta gagccatatt
     1081 cagaaatact tccgactatg gaaaattttt acaagcctct acgaatccaa aatatctttt
     1141 ctcagaaaaa aagagggaga atttattttc gatactacat gagtcaaaac atattgaaca
     1201 atttattgtt gttagtgaaa ttaaagattt gatgaatggt gatattcctt acttttcaat
     1261 ggataccaga ggaaacgtct ataattctgt agggacatta attggaaatt taggagatac
     1321 aacctcgtta tttgatagta taactacttt gaacgatgaa agattgaagt tcacttgtga
     1381 attgcttgaa atagtcttga aaaaaccgat taagcattgg gagagggaaa agggcaaatc
     1441 ttatcagttt ttatcaatct cctcagaaca ttaccttctc taaaattgat aaaactgatt
     1501 ttaggaatat atcggctttt gtatctcaag attctcccat atttgatggg gatgtgatgt
     1561 ataacatttc gctagggaga gaatctgttt caggagaaca ggttattgaa acttgtaaaa
     1621 gggtatcact atatgaggat atcaggagta tgccaatgaa gtttcatacc ccactttttc
     1681 gagacaatcc atcactatct ggggggcaaa aacaacgaat ttctctagca agagagttag
     1741 taactacccc tagaatctta gttcttgatg aacctacatc agctttagat gtaaaaactg
     1801 aaagaataat ccaaaaaaat gttgaggctt tacattgtac gagggttttg gttacccata
     1861 gacttaatac agttgaaaaa gctgataaga ttttaataat ggataatggg aaaattattg
     1921 actatggtag tcatcattgt ttatataaaa ataatgagta ctatcgtgat ttatatgatt
     1981 cgtacatgaa caactatcag gaggaagaga taaaatgaat caattactat tgaaaaatgt
     2041 ttgcaaaagg tatccaaacc aaccgaatta tgctttagac catatcaatt tgactgttag
     2101 aaaaggagaa tttgtagctg tcatgggacg tagtggtagt ggaaaaacaa cacttttaaa
     2161 tgttacttca attattgata aaattgatag tgggagtatt tattgtgcag acaaagaaat
     2221 tagtgcattt tctgataacg aggcaactag ttttagaaaa aatgatattg gttttgtttt
     2281 tcaagattat atgctgttag acagtctaac cattagggag aatatttctg ttgctctatc
     2341 tttaaaaaat gttgattcat caaaaattaa tgatttgata aataactatg caaaaagatt
     2401 taatttatat gagcagttgg aaaaatatcc gtatcaactt tctggaggtc aaagacagag
     2461 ggtcagtatt atcagagcaa tcattaaaga accagagatt atttttgctg acgaaccaac
     2521 tggagcactt gacttaaaat cttctgaagg aacaatgagg attttgagtg aaatcaataa
     2581 aacagaaaag gtaactattt taatggttac tcatgacgtt ttatcagctt cttatgcgga
     2641 tagagttgta cttctcaaag atggtaaact tcacatggag attgataaag aggattgtgg
     2701 agagacgttt tatgatgtaa ttagtcaagc cttatccgat agaggagagt aatatgattt
     2761 ggtccattac aaaatctaac atcaaaaaaa acttttcgtt atatcgtatc tattttctag
     2821 ctacgattgg tttattaagt atttttatag cttttctaaa ttttatctca gataaaatca
     2881 ttacagaaaa aattgggg
//
LOCUS       DAUGUF010000075         2870 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUGUF010000075 DAUGUF010000000
VERSION     DAUGUF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2870
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.075"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            5..1553
                     /locus_tag="VIB71_001688"
     rRNA            5..1553
                     /locus_tag="VIB71_001688"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1605..1677
                     /locus_tag="VIB71_001689"
     tRNA            1605..1677
                     /locus_tag="VIB71_001689"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1638..1640,aa:Ala,seq:tgc)
     gene            1976..>2870
                     /locus_tag="VIB71_001690"
     rRNA            1976..>2870
                     /locus_tag="VIB71_001690"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          815 a          591 c          823 g          641 t
ORIGIN      
        1 gcaaattaaa gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
       61 gcaagtagaa cgctgagaac tggtgcttgc accggttcaa ggagttgcga acgggtgagt
      121 aacgcgtagg taacctacct catagcgggg gataactatt ggaaacgata gctaataccg
      181 cataagagag actaacgcat gttagtaatt taaaaggggc aattgctcca ctatgagatg
      241 gacctgcgtt gtattagcta gttggtgagg taaaggctca ccaaggcgac gatacatagc
      301 cgacctgaga gggtgatcgg ccacactggg actgagacac ggcccagact cctacgggag
      361 gcagcagtag ggaatcttcg gcaatggggg caaccctgac cgagcaacgc cgcgtgagtg
      421 aagaaggttt tcggatcgta aagctctgtt gttagagaag aatgatggtg ggagtggaaa
      481 atccaccaag tgacggtaac taaccagaaa gggacggcta actacgtgcc agcagccgcg
      541 gtaatacgta ggtcccgagc gttgtccgga tttattgggc gtaaagcgag cgcaggcggt
      601 tttttaagtc tgaagttaaa ggcattggct caaccaatgt acgctttgga aactggagaa
      661 cttgagtgca gaaggggaga gtggaattcc atgtgtagcg gtgaaatgcg tagatatatg
      721 gaggaacacc ggtggcgaaa gcggctctct ggtctgtaac tgacgctgag gctcgaaagc
      781 gtggggagca aacaggatta gataccctgg tagtccacgc cgtaaacgat gagtgctagg
      841 tgttaggccc tttccggggc ttagtgccgg agctaacgca ttaagcactc cgcctgggga
      901 gtacgaccgc aaggttgaaa ctcaaaggaa ttgacggggg cccgcacaag cggtggagca
      961 tgtggtttaa ttcgaagcaa cgcgaagaac cttaccaggt cttgacatcc cgatgcccgc
     1021 tctagagata gagttttact tcggtacatc ggtgacaggt ggtgcatggt tgtcgtcagc
     1081 tcgtgtcgtg agatgttggg ttaagtcccg caacgagcgc aacccctatt gttagttgcc
     1141 atcattaagt tgggcactct agcgagactg ccggtaataa accggaggaa ggtggggatg
     1201 acgtcaaatc atcatgcccc ttatgacctg ggctacacac gtgctacaat ggttggtaca
     1261 acgagtcgca agccggtgac ggcaagctaa tctcttaaag ccaatctcag ttcggattgt
     1321 aggctgcaac tcgcctacat gaagtcggaa tcgctagtaa tcgcggatca gcacgccgcg
     1381 gtgaatacgt tcccgggcct tgtacacacc gcccgtcaca ccacgagagt ttgtaacacc
     1441 cgaagtcggt gaggtaacct attaggagcc agccgcctaa ggtgggatag atgattgggg
     1501 tgaagtcgta acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga
     1561 aatggaacac gtttatcgtc ttatttagtt ttgagaggtc ttgtggggcc ttagctcagc
     1621 tgggagagcg cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccatca
     1681 ggatacaatc ctactaaact taatacaagt gaagttgaac acgcaactca cttcctagga
     1741 aaatagacaa tcttcccttg tgtgcaaggc ccacatggtc agattcctaa ttttctacag
     1801 aagtttcgct aaagcgagcg ttgcttggta tcctatataa tagtccattg aaaattgaat
     1861 atctatatca aattccacga tctagaaata gattgtagaa aagtaacaag aaaataaacc
     1921 gaaaacgctg tgactattta ataagttttc tagtttaaaa aaactaggtt aataaggtta
     1981 agttaataag ggcgcacggt ggatgccttg gcactagaag ccgaagaagg acgtgacaaa
     2041 cgacgaaatg ctttggggag ctgtaagtaa gcgctgatcc agagatgtcc gaatggggga
     2101 acccactaac taatggttag tatccataac tgttaaggtt atgagaagga agacgcagtg
     2161 aactgaaaca tctaagtagc tgcaggaaga gaaagcaaac gcgattgcct tagtagcggc
     2221 gagcgaaacg gcaggagggc aaaccgaagt gtttacactt cggggttgta ggactgcgac
     2281 gtgggacttt aaaaggatag aagaattacc tgggaaggta agccaaagag agtaaaagcc
     2341 tcgtatttaa aattcttttg agccctagca gtatcctgag tacggcgaga cacgtgaaat
     2401 ctcgttggaa tctgggagga ccatctccca accctaaata ctctctagtg accgatagtg
     2461 aaccagtacc gtgagggaaa ggtgaaaagc accccgggag gggagtgaaa tagaacctga
     2521 aaccgtgtgc ctacaacaag ttcgagcccg ttaatgggtg agagcgtgcc ttttgtagaa
     2581 tgaaccggcg agttacgata tgatgcgagg ttaagttgaa gagacggagc cgtagggaaa
     2641 ccgagtctta atagggcgat ttagtatcat gttgtagacc cgaaaccatg tgacctaccc
     2701 atgagcaggt tgaaggtgag gtaaaactca ctggaggacc gaaccagggc acgttgaaaa
     2761 gtgcttggat gacttgtggg tagcggagaa attccaaacg aacttggaga tagctggttc
     2821 tctccgaaat agctttaggg ctagcgtcga tgttaagtct cttggaggta
//
LOCUS       DAUGUF010000076         2707 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUGUF010000076 DAUGUF010000000
VERSION     DAUGUF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2707
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.076"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            49..720
                     /gene="sdaAB"
                     /locus_tag="VIB71_001691"
     CDS             49..720
                     /gene="sdaAB"
                     /locus_tag="VIB71_001691"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEQ8823403.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVYSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            732..1604
                     /gene="sdaAA"
                     /locus_tag="VIB71_001692"
     CDS             732..1604
                     /gene="sdaAA"
                     /locus_tag="VIB71_001692"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEQ8823404.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKKQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIESQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(2018..2632)
                     /locus_tag="VIB71_001693"
     CDS             complement(2018..2632)
                     /locus_tag="VIB71_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEQ8823405.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
BASE COUNT          849 a          497 c          500 g          861 t
ORIGIN      
        1 gatatttttt tgttataata aacatagaaa taaaaaacgg agttgcctat gaatacacaa
       61 aaatttcaat cagtttttga catcattggg ccagtaatga ttggtccatc aagtagtcac
      121 acagctggtg ccgtcagaat tggtaaggta gtctattcca tctttggaga tattcctgat
      181 gaagtgacgt ttcaccttta taattcattt gctaaaacct acagaggaca tggtactgat
      241 aaggctcttg ttgcaggaat tatgggtatg gatactgata atcctgatat taaaaattct
      301 ctagaaattg ctcatcaaaa agggataaaa atctattggg atatcttaaa agatagtaat
      361 gctccccatc ccaatactgt taaaatcagt gtcaaaaaag ctgacaaaac acttagtgtt
      421 actggtgttt caattggagg aggaaacatt caagtaacag aactaaatgg tttttctgtc
      481 tcgttatcca tgaatactcc tactatagtt actgtacaca aagatattcc cggaatgatc
      541 gcaaaggtaa ctgatatcct atcttccaat aatattaata tcgccacaat gaatgttaca
      601 cgtgaatctg ctggtgaaaa agctactatg attatagaag tcgattctag agagtgccaa
      661 gaagcagcca accaaattgc aaaaattcct catatttata atgtcaactt ctttgactag
      721 aaaggaaagc tatgttttat actattgaag aacttgtcaa acaagctgac caacaattta
      781 atggaaatat tgctgaactc atgattgcca cggaagtgga gatgtctgga agaaatcgag
      841 aagatattat caaaatcatg tcacgcaatt tacaagttat gaaagcagct gtaacagaag
      901 gactaacctc aaccaaatct atcagtggtt tgacaggggg cgatgcggtc aaaatggata
      961 actacattaa aaaagggaac agcctttctg atactactat tcttaatgct gttagaaatg
     1021 ctatagctgt aaacgaatta aatgctaaaa tgggacttgt ctgtgcaaca cccactgcag
     1081 gaagtgcagg atgcttacca gcagtgctcg caacagctat tgaaaaactt gacttatcag
     1141 aaaaaaaaca attagagttt ttatttactg caggagcttt tggtcttgtt attggaaata
     1201 acgcctctat ttctggtgca gaaggtggat gccaagcaga agttggttct gcagctgcta
     1261 tgagtgcagc tgctcttgtt aaagcagctg gtggaacatc tcatcaagct agtcaagcta
     1321 ttgcgtttgt tatcaaaaat ttattaggac ttgtctgtga tcctgttgcc ggcctagtag
     1381 aagtgccttg tgtcaaacgc aatgccctag gagcaagttt cgcccttgtc gcagctgata
     1441 tggctttagc tgatattgaa tctcaaattc ctgttgacga agttattgat gctatgtatc
     1501 aagtcggctc tgccatgcca actgctttcc gtgaaacagc agaaggtggt ctagccgcta
     1561 ctccaactgg acgacgttac agcgtagaaa tatttggcga ataaatagat agttagaaaa
     1621 attcttagaa atatttgaaa gcgttttatt tttatgctat atattcacta aaatgactaa
     1681 tagatagcta tcaagctatg ttgtttcccc ttagaaacaa cttctagtaa attgttaaaa
     1741 ctcaaaagtg tagtagtgta aaatactgaa aattgctaat gaccttataa acatttaaga
     1801 gtttttttcc tgcttgttat cagtataact gccttaaata tcagaggcac ttaagtgctg
     1861 gtcagttttc ctaaataata cgagctatat tccctgataa ggcaatgttt tgttttgaga
     1921 ctaattcatc actacaaatc ataaagacaa ttaaatacca aaaacctatt gttagtaaat
     1981 actaacaata ggttttattt cttccagcca tgtttattta gtaaccccaa gctgataaac
     2041 cttgtgcact ataggctttc aaggctgcat tgacttgatc ttcaaccgtt gctgtagaac
     2101 cccaacctgg cattgtctgg aacaaccctg atgccccaga agcattagct gcgttaggat
     2161 ttccattaga ttcacgcgca attatatgtt cccaagttga ttgtggaaca cctgttgctg
     2221 ctgccatctg tgccgccgct tgacttccta caataccagc agtatttcca ttggaaagta
     2281 ccacattgtt tggattatag gctactgaag atacctgctg aacagtttga gtcacttctt
     2341 gctgaacaac cggtgcttcc tctgttactg tcggagctac agagttttct actgtgggaa
     2401 taggctccga agcaatgctc tttgcttttt ctttgctttc ttctttagta atagcatgat
     2461 tattttttgg agccttgtcg attgttacca ttttactttc tgacttctta gcataagact
     2521 tagtatcagc atttttactt gagaaggcaa aaatgatggc taatattgtt agagctaacg
     2581 ctactaatcc aaaattaaaa taacgttgtt ttaaattttc tttcttaaac attcaataat
     2641 acctcacttt tctccgttat ccataatatc ttttaattat tacctcgtta ttgaagatat
     2701 attaaaa
//
LOCUS       DAUGUF010000077         2699 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUGUF010000077 DAUGUF010000000
VERSION     DAUGUF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2699
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.077"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            382..674
                     /locus_tag="VIB71_001694"
                     /pseudo
     CDS             382..674
                     /locus_tag="VIB71_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            849..1174
                     /locus_tag="VIB71_001695"
                     /pseudo
     CDS             849..1174
                     /locus_tag="VIB71_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            1165..1439
                     /locus_tag="VIB71_001696"
                     /pseudo
     CDS             1165..1439
                     /locus_tag="VIB71_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            1485..1697
                     /locus_tag="VIB71_001697"
     CDS             1485..1697
                     /locus_tag="VIB71_001697"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823406.1"
                     /translation="MMTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLL
                     NRANSLEELLLKAKEVNLTIDLKQKM"
     gene            1962..2659
                     /locus_tag="VIB71_001698"
                     /pseudo
     CDS             1962..2659
                     /locus_tag="VIB71_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
BASE COUNT          949 a          405 c          575 g          770 t
ORIGIN      
        1 tctagtaata atttttttat tttcaggagg aaaatcatgc aaatgaatga acagtcatca
       61 cgacaaatgg tgattgccat ctatctcatt tattccaact caaaatgata gtactccttg
      121 gctgttccaa gtcgaaattg ttagtgatta agaaaaccta cgagactatg gtttgatcga
      181 tgaaggccag cagtctccca gtgaaaaagg gcgtttggct aataagattt atttaggaaa
      241 gttggaacat gatttcaccc cagtcttaag ttcagacggg gccagtctca aaaacagacc
      301 agccccgtgt taaattcagc ccctagtgag actgaaaaga gtgaaactga aggtagtgaa
      361 actaaagaga gtaatttagt cattgaggac gaggaggaaa gaaaggagtg cactagtgtg
      421 aaaaagactg agggtcactt tactcgtcaa gttgatcatg tcaccaaata tgacaaagat
      481 tatatttgga gtttggttca ttcccaatta cgtgaggtgg tttatcacaa gctgctagtg
      541 acttagtcat gagctatttt gaagaacgct atgcttatgc gctggaacac atacggttcg
      601 caagaacagc tgaagctatt gcggaatatg tctttaatgg tgtcttatcc gaatggacca
      661 agcaactaag gtgacaagaa gcgaagtgag taagatgttt tggtggctat tattaggtgt
      721 ttggggacta aggacaattt ggttgattat tgaagttatc actgcaccag aaatggaaga
      781 ttatagttga gtaaggacgt tacataagca gtaaggtcct tttattttgt cagaaaggaa
      841 tgagagatat gcagttttta gatttgtttg caggaattgg aggctttcga ttgggtttaa
      901 ttaatcagtg ccatgagtgt attggctttt gtgagattga taagtttgcg aggcaatctt
      961 acaaagccat ctatgagacc gaaggagaaa tagaatttca tgacattaga caagtcacag
     1021 accaagactt tagacaactt agagggcaag tggatatcat ctgcggtggt ttttcccttg
     1081 tcaagcattt tcactcgcag gcagacgact gggatttgag ggcactagga gaactctctt
     1141 ctttgagatt actcgagcga ccaaacagat aaaaatcata cccataatca catccaatca
     1201 acgccattga ccgtaattca gataaaaaat tgatatggaa ttatgccttg gaacgaaacc
     1261 tccgtatgat ttcagaccgt atttcaaaaa tgactggagc aaaaattatc gagaagcgtt
     1321 attcctaccg tgactatcaa aaatataggc agtctagtca taaatttgaa ttgaaacaac
     1381 gtctttattt tttgatgcag cagtcaaagt tctttgatga ttttttagaa aaagcagagt
     1441 aattacatgt tcatattgat tttagtcaga agcatagcag attcatgatg acggatcgag
     1501 taatgaaaaa accaattcga ggccgtcaac tcagtaaacg agatttatat gatgaagaat
     1561 tttttcgtac acattttgcc aagatagaaa ttgaaagtcg attagaattt ttgttgaacc
     1621 gtgccaattc attagaggag ctactattaa aagcaaaaga agtgaatcta accattgact
     1681 taaaacaaaa aatgtaactt ttatcctaga agaagatact caaaagataa gtttaggtca
     1741 taaaaaaata agcgataaga aattatatga tgtcaatttt ttcaagatta ctttaaaaat
     1801 aaggaagtcg gtgtttcaga tcgattagaa agtctacaga aacagtacat gcttttcaag
     1861 aagaacgaga taaagaggag gtatccactg aagagagtaa ggaagtcttc aagaaataca
     1921 aggggcaacg agatgccatc catgagtttg aagttgaact tgtggaacat caaattgaga
     1981 ggttaattgc tgaggacatt tatattaagg tgtcttttgg tgtaaagcag agtggtctta
     2041 ttttcattcc taactatcaa ttggatatta ggaaagaaga aaatcataaa aaatataaag
     2101 tctatattcg tgagaccgca caattcttca tttacaacaa ggaggcgtct aaacttaatc
     2161 gctatatgcg agggcgtgag ctcatttacc agttaaccaa tgatagcaag agtattccaa
     2221 aaagaagacg accaaaacca ttgatacact taagaaaaag attgaagaaa taagtctcct
     2281 cattgagtta gatacggaga ataagcctta tcaagatatt aaagatgaca ttgttaaaga
     2341 tatggctcaa ttagatttga ccattacaga gttgcaggac catattgctc atctcaataa
     2401 ggttgcggag gtcttgctta atatgaacaa caacgatata gagaaccgcc gtttggccag
     2461 atatgactat gccaagatga acttgactgc agctataaaa atagaagaag ttgagaaaga
     2521 gattgaaact tctcaaaatg aacttaatat atccatagat gagtatgaat atctagtaag
     2581 aaggttggaa aagtttggag agatcttgag ttatagcaaa attatcgata cttctcgaaa
     2641 tgaaatacaa tgggagtaat tatgatataa tttgggtggt agcaattttt atatcagat
//
LOCUS       DAUGUF010000078         2599 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUGUF010000078 DAUGUF010000000
VERSION     DAUGUF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2599
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.078"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..271
                     /locus_tag="VIB71_001699"
     CDS             <1..271
                     /locus_tag="VIB71_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ8823407.1"
                     /translation="GQRHHNTNTFDYSKFNSYIPYINYIFYRISSNPGLKEDEKVIDF
                     VKRCNNLISSDYSAESWYSERQMQDVIKKINEKYTILEDSGRESD"
     gene            640..1932
                     /gene="purB"
                     /locus_tag="VIB71_001700"
     CDS             640..1932
                     /gene="purB"
                     /locus_tag="VIB71_001700"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEQ8823408.1"
                     /translation="MIERYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEQYVCYKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDIKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
     gene            2065..>2599
                     /gene="rgg4"
                     /locus_tag="VIB71_001701"
     CDS             2065..>2599
                     /gene="rgg4"
                     /locus_tag="VIB71_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEQ8823409.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     LILLELYLAYLDIEGMDG"
BASE COUNT          848 a          428 c          567 g          756 t
ORIGIN      
        1 gggtcaacgt catcataata caaatacttt tgactattca aaatttaatt catatattcc
       61 ttatattaac tatatatttt ataggatatc atcaaatcct ggattaaaag aagatgaaaa
      121 agtaatagat tttgttaaga ggtgtaataa tttaatttca agtgactata gtgcagaatc
      181 ttggtatagt gagcgtcaaa tgcaggatgt aattaaaaaa attaatgaaa aatacactat
      241 attggaagat agtggaaggg agtcggatta atcaaattaa atttggtaga gagtttagga
      301 aatctaactt actcattcta aatgctaagg aaattaagtt aaaaaataga aagaaacaaa
      361 ggtagtcgta ttcgctaaac tgaatacagg ctacggactt ccttaactca cagaatttta
      421 agaaatacaa gaaaggagtg agggtgtttc cgagtatttg aactcgggct aacttatctc
      481 ctcaatacaa atcaaataat agaaaggaaa tgggcactag tttcactaaa ctgaacccga
      541 gcggaaagct cggaatttag ataaaccgcc taggacgcaa gcgtccattg ttggtttcct
      601 aaaattcagt cgctttctgg tcgcccttgg tatcttaaaa tgatcgaacg ttattcacgc
      661 cctgagatgg cggcaatttg gacagaggaa aataaatacc gtgcttggtt ggaggttgag
      721 attttggctg acgaggcatg ggctgagttg ggtgagattc ctaaggagga tgtggctaag
      781 attcgtgaga aggcggattt tgacattgac cgcattcttg agattgagca ggacacacgt
      841 cacgatgtgg tggctttcac tcgtgcggtt tctgaaacgc ttggtgagga gcgcaagtgg
      901 gtgcactacg gtttgacgtc aactgacgtg gtggacactg cctacggtta cctctacaag
      961 caagctaacg acattatccg tcgcgatctt gagaatttca ccaatatcgt ggcagacaag
     1021 gcgcgtgagc acaaaatgac catcatgatg ggtcgcaccc acggtgttca cgccgagcca
     1081 acgactttcg gtcttaagtt ggcgacttgg tacagcgaga tgaaacgtaa tattgagcgt
     1141 tttgaacatg ctgccgcagg tgtggaagct ggtaagattt caggtgccgt tggtaacttt
     1201 gctaatatcc ctccatttgt ggaacaatat gtctgttaca aattaggcat tcgtccacaa
     1261 gagatttcaa cacaagttct tccacgtgac ctccacgcag aatattttgc agtgcttgca
     1321 agtattgcaa cttctatcga acgtatggcg acagagattc gaggtctgca aaagtcagaa
     1381 caacgtgaag ttgaagaatt ctttgccaaa ggtcagaaag gtagctctgc tatgcctcac
     1441 aaacgcaacc caatcggttc agagaacatg acagggctag cgcgcgtgat tcgtggtcac
     1501 atggtgacag cttatgagaa cgtgtcactt tggcatgagc gtgatatttc acactcatca
     1561 gctgagcgta tcatcacacc tgacacaact atcttgattg actacatgct caaccgcttt
     1621 ggcaatatcg ttaagaactt gactgtcttc ccggaaaata tgatgcgcaa tatggaatca
     1681 acttttggtt tgatttatag tcaacgtgtt atgctcaaat tgattgaaaa aggaatgaca
     1741 cgagaagaag cttatgactt agttcaacct aagacagctt attcctggga caatcaagtg
     1801 gatttcaaac cacttttaga agaagacatc aaagttacct cttgtcttac acaagaagaa
     1861 attgatgaac tatttaatcc gatttattac acaaaacgtg ttgatgatat ttttaagcgt
     1921 ttagggattt aatataaaaa aaagaaggtg attcccttct tttttgttta aaaaaacgaa
     1981 tattttcttt aaaaatatta aaaaggttag ttttttgatt agacgctgtg atataataaa
     2041 gaaaacagtt gttggagaga aaccatgtta gaacattttg gtggaaaagt aaaagtgtta
     2101 agacttgaaa agaggattag tcgcgaggac ttgtgtgggg atgagtctga actttctgtt
     2161 cgtcaattag cacggataga actaggtcaa tccataccaa gtttaagtaa ggttattttt
     2221 attgcaaaag ccttaaacgt tagtgtcggt tacttaactg atggtgctga tttagaacta
     2281 cctaagcgtt acaaagaatt aaaatacctt atcttaagga caccaactta catggatgat
     2341 ggaaaattac aagtacgaga agagcagttt gatgaaattt ttgaggatta ttatgataaa
     2401 ttaccagagg aagagaaaat aatcattgat tgtttacagg caactttaga tactttattg
     2461 agtgagaata ctaactttgg cattgactta cttcaagaat attttaatca aataaagact
     2521 aaggtacgct ttaggcaaaa tgatttaata cttctagaat tatatttagc ttatcttgat
     2581 attgagggaa tggatggac
//
LOCUS       DAUGUF010000079         2425 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUGUF010000079 DAUGUF010000000
VERSION     DAUGUF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2425
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.079"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..228
                     /locus_tag="VIB71_001702"
     CDS             <1..228
                     /locus_tag="VIB71_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ8823410.1"
                     /translation="DKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTGGFGLG
                     LALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
     gene            complement(353..601)
                     /locus_tag="VIB71_001703"
     CDS             complement(353..601)
                     /locus_tag="VIB71_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEQ8823411.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(655..1575)
                     /locus_tag="VIB71_001704"
     CDS             complement(655..1575)
                     /locus_tag="VIB71_001704"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEQ8823412.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKCDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1810..>2425
                     /locus_tag="VIB71_001705"
     CDS             1810..>2425
                     /locus_tag="VIB71_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ8823413.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLETLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSI"
BASE COUNT          819 a          337 c          449 g          820 t
ORIGIN      
        1 gacaaaaatt tattaatttc tgttattgat aatggtccag ggataacaga tgaagaaaag
       61 aaaaagattt ttgatcgttt ttatcgagtt gacaaagcta gaacacggca aacaggtgga
      121 tttggcttgg ggttggcttt agctcagcaa atcgtgatgt ctttaaaagg aaatattaca
      181 gtaaaggata atgatcctaa aggtagtatt tttgaagtca aattataagc taaaaagggc
      241 gaccaataag gtcagccctt ttaaagttat ttttaactgt caacgcttta ttgtattttt
      301 tgagttttta ccgtataaaa aaactccagc tggagttttc attggatatt tattagccaa
      361 gttttgcagc aaggcgtgct ttatcgcggc ttgctttgtt tttgtgaatc aaaccttttg
      421 attcagcttt atcgatgctt gaagaagcag cgcggaaaag ctcttcagat gggttagctt
      481 caaatgcttt gatagcagta cgcatagctg atttttgtgc tgagtttttt tcgtttgctt
      541 taacgttaag ttcagcgcgt ttaatagctg atttaatatt tgccaatgtt ttcacctcca
      601 aattaatcta actacattat tatatagaaa atatatgcgt ttggcaaccc tttatcactt
      661 tttgaggtaa atttcatcaa ttttatgatc agcactttta tgtaaaatta attcagcacg
      721 gttacgtgta ggttcaatga atttttcaag attttctaaa ttaacggttt tccaaacgtt
      781 gcgcgcaaat gctatagcct cagatcgagg taattgtgca tattgggcat aataattatg
      841 agggtcacat tttgctaatt ttaaaatgct tagaaaccgt tcaatgtacc aggtttcgat
      901 gtgactgctg tctgcatcaa tataaataga aaaatcaaag taatcactca tatataaacg
      961 attgttttgt tgattttgaa aaacattaat accttcgacg ataaggaagt cagggttatt
     1021 aaatgattgt ttttgatttg ggataatatc gtaaatatca tgagaataga cgggtgcaaa
     1081 agcagtttga ccatttttga tggaatctag aaaatctaag agaagttcca tgttataaga
     1141 ttctggaaat cctttacgat ttaacagtcc ttgttcaata agaaactgat taggatataa
     1201 aaaaccatca gtcgttacca gttcgacttg actattgggg tgcgttcgtg ataataaaag
     1261 ttgtaaaaga cgactagttg ttgatttacc aacagctact gaaccagaaa ttccaataat
     1321 aaaaggcctt aattgaatgt ctttttttag aaaaaggctt ttagaaaaag aaagattttc
     1381 ttgcgcaatt ttgtaaacct ggatcagatt aattaatgga aggtagatat caatgacatc
     1441 gttaatactg atgttatcat ttaagctagt aatactttta agttcctctt gtgtgagaag
     1501 agcttttgct ttttgatgta atgttttcca agactctcta gaaatttttt caaagttgat
     1561 aaattcattt gacatggtag ctcctaatca tttgacagtg cttacattat accattttag
     1621 ttaaaaaata aataattttt cgttagtatt tacacgaaaa ttaatacaat taactcaaaa
     1681 aagccacaca ttcctagtac aattatcctg ctatattcta acaaatagtt aaagttcggt
     1741 ttttatttgt aatatagaga aaattgttaa ggaacaagcg tcttgtaaac catttcaaag
     1801 tatgatagaa tgaaaaagta ccttaaaaag ataggaaaaa tgatgacaaa gatgtattat
     1861 gatgaaaatc cagatagcct acacgatatt catgaagtaa aagtagagct gcttaatcat
     1921 ccctttactt ttttgacgga ttcaggtgtc ttttcaaaga aaatggttga tttcggtagt
     1981 caagtattat tagagacact aaatttcaag gagaacgaac gtgtactgga cttaggttgc
     2041 ggctatggtc ctcttgggat tagtctagcc aaggttcaaa gggtagacgc aaccttagtg
     2101 gacatcaata atcgtgctct tgatttagct agaaaaaatg caactaataa ccaagtggca
     2161 gtaactattt ttcaatcaaa tatttatgaa aatattagtg gccattttga gcatattatt
     2221 agtaatcctc ctattagagc aggaaagaga gtagttcata gcattattga aaaaagcata
     2281 gattttttag tggttaatgg tgacttaacg attgtgattc aaaaaaaaca aggagctcct
     2341 agcgctaaag caaaaatggc aactattttt ggtaatgttg agatactaag gaaagataaa
     2401 ggttattatg tattaagaag tataa
//
LOCUS       DAUGUF010000080         2145 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUGUF010000080 DAUGUF010000000
VERSION     DAUGUF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2145
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.080"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..1965
                     /locus_tag="VIB71_001706"
     rRNA            <1..1965
                     /locus_tag="VIB71_001706"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            2051..>2145
                     /gene="rrf"
                     /locus_tag="VIB71_001707"
     rRNA            2051..>2145
                     /gene="rrf"
                     /locus_tag="VIB71_001707"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          599 a          445 c          620 g          481 t
ORIGIN      
        1 agataaactc cgaatgccaa cgagatatca tcggcagtca gactgcgagt gctaagatcc
       61 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaataac tgttaagtgg
      121 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
      181 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
      241 acagtttacc gaagctgtgg atgacacaaa agtgtcatgg taggagagcg ttctatgtgt
      301 gaagaaggtg taccgtgagg agcgctggaa cgcatagaag tgagaatgcc ggtatgagta
      361 gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg gaaggctcgt
      421 ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat ggccaacagg
      481 ttgatattcc tgtactagag tatatagtga tggagggacg cagtaggcta actaaaccgg
      541 acgattggaa gagtccggct aagcagtgag gtgtaagatg agtcaaatgc ttatctttat
      601 aacattgagc tgtgatgggg agcgaatttt agtagcgaag ttagtgatgt cacactgcca
      661 agaaaagctt ctagcgttta atgatactct acccgtaccg caaaccgaca caggtagtcg
      721 aggcgagtag cctcaggtga tcgagagaac tctcgttaag gaactcggca aaatgacccc
      781 gtaacttcgg gagaaggggt gctgacttag gtcagccgca gtgaataggc ccaagcaact
      841 gtttatcaaa aacacagctc tctgctaaat cgtaagatga tgtatagggg gtgacgcctg
      901 cccggtgctg gaaggttaag aggagggttt agcgcaagcg aagatctgaa ttgaagcccc
      961 agtaaacggc ggccgtaact ataacggtcc taaggtagcg aaattccttg tcgggtaagt
     1021 tccgacccgc acgaaaggcg taatgatttg ggcactgtct caacgagaga ctcggtgaaa
     1081 ttttagtacc tgtgaagatg caggttaccc gcgacaggac ggaaagaccc catggagctt
     1141 tactgcagtt tgatattgag tatctgtacc acatgtacag gataggtagg agccattgac
     1201 ttcgggacgc cagtttcgaa tgaggcgctg ttgggatact acccttgtgt tatggctact
     1261 ctaacccaga taggttatcc ctatcggaga cagtgtctga cgggcagttt gactggggcg
     1321 gtcgcctcct aaagagtaac ggaggcgccc aaaggttccc tcagattggt tggaaatcaa
     1381 tcgcagagtg taaaggtata agggagcttg actgcgagag ctacaactcg agcagggacg
     1441 aaagtcgggc ttagtgatcc ggtggtaccg aatggaaggg ccatcgctca acggataaaa
     1501 gctaccctgg ggataacagg cttatctccc ccaagagttc acatcgacgg ggaggtttgg
     1561 cacctcgatg tcggctcgtc gcatcctggg gctgtagtcg gtcccaaggg ttgggctgtt
     1621 cgcccattaa agcggcacgc gagctgggtt cagaacgtcg tgagacagtt cggtccctat
     1681 ccgtcgcggg cgtaggaaat ttgagaggat ctgctcctag tacgagagga ccagagtgga
     1741 cttaccgctg gtgtaccagt tgtcttgcca aaggcatcgc tgggtagcta tgtagggaag
     1801 ggataagcgc tgaaagcatc taagtgcgaa gcccccctca agatgagatt tcccatgatt
     1861 ttatatcagt aagagccctg agagatgatc aggtagatag gttaggagtg taagtgtagc
     1921 gatacatgta gcggactaat actaatagct cgaggactta tccaaaaaga aatattgaca
     1981 acgttacgga ttcttgttag actatagata ttcaattttg agtgggttat gaaaatagca
     2041 catttacaag ttaagtgacg atagcctagg agatacacct gtacccatgc cgaacacagc
     2101 agttaagccc tagaacgcct gatgtagttg ggggttgccc cctgt
//
LOCUS       DAUGUF010000081         1987 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUGUF010000081 DAUGUF010000000
VERSION     DAUGUF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1987
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.081"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            1..1278
                     /locus_tag="VIB71_001708"
                     /pseudo
     CDS             1..1278
                     /locus_tag="VIB71_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(1506..>1987)
                     /locus_tag="VIB71_001709"
     CDS             complement(1506..>1987)
                     /locus_tag="VIB71_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="competence protein"
                     /protein_id="HEQ8823414.1"
                     /translation="YKIPYLEGYLKGKEEHSKSNAEVPSGKNPHSQNEPRMPENNIPS
                     PGKDTIPEPPHSEWPQRDPNFGGLSFGQSSDWGRSEDNPNSPSEPRIPGSSIPSPRLP
                     QASENPKEDTSTLTYEKGLEDGRKAKLTNKIDYSRLSDRPDNPFPRDYVRGYFEGIK"
BASE COUNT          571 a          403 c          422 g          591 t
ORIGIN      
        1 ttggttaaaa tccctctgat tcagtgcttt tatggcattc gttccatgcg tcagaccatc
       61 aaggatattg aagtgaatac tgcctatcgc tggtttttag gtttgacttt ggatgacaag
      121 gtgccacatt tcacaaccta tggcaaaaat tattcccgtc gctttcaaga aaaaggcttg
      181 attgagtcta tttttacgca tattcttggg ctatgtatca atacaggcct gattgacccg
      241 acggagattt tcatagatgg gactcatatt aaggctgcgg ctaataatcg caagttcatc
      301 aaccgagagg tggaaaaaca agccaagttc atgagtgaac agctagaaat cgaaatcaat
      361 cgggataggg agaagcatgg aaaaaagccg ctagggcccg ccaaagagct agagtccgtc
      421 gctaagaaaa tctccacaac cgatacagaa agtggctggt ttcacagatc ataaggaagt
      481 cttcgcttat tctgctcagg tggcttgtga caagtatgga tgggcgcttg cttatagtgt
      541 tgaggctggc aatatccatg atagtcaggc ttttcctgca ctttttgcca agcttgaacc
      601 cttgaaacca cagtttatta ttgcggattc cggctataac attcccagca ttgccaagtt
      661 tctgattgat aaggagatca cttctgtcct tccgtacaca cgaccaagag gaaagaaaga
      721 ccttctacgt ccgaaagaat ttatttatga tgagcacttt gattgtgtca tctgccctga
      781 acatcaagcc ttgacctacc gcactacgac cagagaaggc taccgagaat acaaaagtga
      841 ccctgtaatt tgtgccaatt gtcccctgtt atctgtatgt acgaccagta agaaccacct
      901 aaaagttgtc acacggcata tttggaaaga ctatttggaa cagtgcgagg acattcgtca
      961 tcaaaggggg atgaaggagc tctaccagca tcggaaagag acgattgaac gactgtttgg
     1021 cacagccaag gaataccaca atctccgcta tacgagagag aaaggcaagt ccaaaatgga
     1081 agataaggtt ggactgactt tggcatgctt aaatctcaaa aaactggtca aaaggatggc
     1141 gggagagcct ttttattttg ttcagatgag gtggtttaag cacggaaaca gccattttta
     1201 tctaaaaaca ctaaaaaaga caaacaccaa atcgatgttt gtcttcaatc tgttctagag
     1261 actttttctt tattctgagc gatagttgtc ataccatgct tttttagatg agtacactgc
     1321 actcttttat aatggtttta gtgtccgtgg aataaagagt tcagcattat actcactatt
     1381 gttaacttca ctatcacttt attcaatgta tcatagtcta accaagattg ctagttttcc
     1441 caatgatagt caccagcaat tcaggtagtg gcaatatgct acccgtctcc taagcaagaa
     1501 tctttctatt taataccttc aaaataacct cttacataat cccttggaaa ggggttatcg
     1561 ggtctatcag aaagacgtga gtaatctatc ttgtttgtca attttgcttt acgaccgtct
     1621 tccagccctt tttcataagt taaggttgat gtatcttctt ttggattctc tgaagcttgt
     1681 ggtaatcttg gcgatggtat actacttccc ggaatacgag gttcacttgg ggaattaggg
     1741 ttgtcctcag atcggcccca atcagaggat tggccaaatg ataatccacc aaagtttgga
     1801 tccctctgag gccactcact atgaggaggt tcaggaatag tatctttccc tggcgatggt
     1861 atattatttt ccggcatacg aggttcattt tgggaatgag ggtttttacc agaaggaact
     1921 tcagcatttg atttactgtg ctcttctttt ccttttaaat aaccttctag ataaggaatt
     1981 ttataat
//
LOCUS       DAUGUF010000082         1655 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUGUF010000082 DAUGUF010000000
VERSION     DAUGUF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.082"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..1485)
                     /locus_tag="VIB71_001710"
     CDS             complement(<1..1485)
                     /locus_tag="VIB71_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEQ8823415.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDTFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKVSHRKILEDELLENKAAYIVVNRYKNLPKIIQ"
BASE COUNT          627 a          292 c          264 g          472 t
ORIGIN      
        1 ttgaatgatt ttaggcaggt ttttatagcg gttaacaacg atataagcag ccttattttc
       61 taatagttca tcttctaata tttttcgatg actcactttt tgcgtattga tgtcaggaga
      121 actaaattga gaaacagatt tagctttact gtccaaataa attttagaag tatcatccca
      181 aacataaata gattgagttt tatttagttt ctgttctaaa taactagcaa tatgatcacg
      241 ctcctgatta agaggaatac tactaatgaa acaataagta gaacagatta gtattgtccc
      301 tacaattaaa attggcaaat aaaagtgtct cttaagataa atcatcatta ctcgaccaac
      361 accattttta ccatgacgtc tgcgatgact actctgacct aatcctatac catactgata
      421 gccaacagga atagcagtca aaattaatcc aaaaggtaaa agaggtaaaa gatgataggg
      481 gcgatagtct tgtgaaaata tagccacaag tatagattct agaatgacca tgacaaatag
      541 ccacttgacg accctatcag aattgttttt aaatcgccta atgacattct ccatccccgt
      601 caaaagacca agccccaaag cgaagaacaa ctgaatagcc agtccaaaaa gcaacgataa
      661 gtttcctgat ttaaaaaaag taaaaggata aatcatcgtt tgtgataaat aaggatttag
      721 cacttgtaag ttcaaaatga aatatcctgc tgtgtaaaaa actaaaatca ttccaaaaat
      781 cgaagctagc agttgataaa aacctcttgc aagatgcttt tggcttatat tataagaaaa
      841 aactgtcaca caagcaaaag accaaaagat aagggtactc gggtcaatta gcattgcaag
      901 agcacctaca aagccaaaaa gaataaatgc ctcatctttc actaaacagg caaaatactt
      961 agttaaaaac caagccgata ttaatataaa tggcatagcc agttgagtag gatacaatcc
     1021 cccaaaacca agactaacag acaacaaata gtagctaatt gaaaaagtta aagccacttt
     1081 ttgaaagcct gtcatataat taatgagttt ataaagatat aaaccagata agtaaaaaca
     1141 aaacacctga acaaagacta gccaaagtgt cgatcccaaa taataactta atgcaatgat
     1201 aacaaagtaa aagagccctc ctgttgtaaa agtatcacta tagggaagtt gccccttcgt
     1261 taacatcatt cctatatata agttttggga ctgaagacca ttggctgcat ctgttaaaaa
     1321 aggtactgca attgttaaag aactgataat aatgctaaag aaaagcagat agcatttatg
     1381 aagccgaggt actttagttt catattgagt ggtgtgtact cgtgggccat cgttggccag
     1441 ttctatcgtc tcttttcgga tgaattcatc gtttaactcg atcactattt ttctccttga
     1501 aatatcatat tctctaacga ttcaataaaa gcaatatttc ttcatgtcac tagtctaaca
     1561 tagctattat ccattatttt ttagtatgag ttaaataaca tgactttgta ttgcacatag
     1621 caaagtgaca gtgcataaac aaagtaagtt gaaaa
//
LOCUS       DAUGUF010000083         1559 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUGUF010000083 DAUGUF010000000
VERSION     DAUGUF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1559
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.083"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            202..936
                     /locus_tag="VIB71_001711"
     CDS             202..936
                     /locus_tag="VIB71_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ8823416.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSVAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIRGLDYKWSENTSIKEALNE"
     gene            929..>1559
                     /locus_tag="VIB71_001712"
     CDS             929..>1559
                     /locus_tag="VIB71_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ8823417.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKMFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKH"
BASE COUNT          585 a          187 c          314 g          473 t
ORIGIN      
        1 atgttaacaa tgatttagga atacattatg tagaactagg taaaggaatt atcgattata
       61 aaacaatcat tcatgaaatc catgaacatt ttatagactt aatttttagt ttagaagtac
      121 atgaaaaaga aatagacaaa aaggcagaag tagtgaggaa gtcttatctg acactaaatg
      181 agtatattaa tggaggctaa aatgaatttg agtatatttg gtttaaagaa tattccttat
      241 ttgaaagaag gggatagtat agaaaagctt attgaagaaa gcattaaaac ttcaggattt
      301 tttatcgaag acaatgatgt gctttgcata gcttctaaag ttgtatctgt cgcagaaggc
      361 caggtgatgt ctttaaacga gatacaagtg agtgatgtag caaaagaaat ccacaggaat
      421 attcctcgta aagatcctag aataattgaa attatgctaa atttagtcaa tagagatctg
      481 tcacgtttag atatcaaaaa aaattacatt ggttgtcgct tggaaaatgg tttaaagttg
      541 acaagtggtg gaatcgatag aaaatcagta gatgaagtat ttcttttacc taataatccg
      601 gatgcttctg caaaaagaat ttcggaatat cttaaaaaat cacttggaaa aaatgttgca
      661 gttgttataa cagatagtga tggtagagag gataaaagag gtgctactca agtagcaatt
      721 ggtatttatg gtattcatcc tttgagaaaa acagaagtaa tagattcaca aggagagaca
      781 ataaaattcc aagaagagac tttgtgtgat atgattgcag cttgtgctgg cttagtaatg
      841 gggcaacgtg gaactggaat tccagctgtc ctcattaggg gcttggatta taaatggtct
      901 gaaaatacta gtattaagga agcgttaaat gagtagaaat caggactgta agaatattct
      961 aatcattggt tttggaaaaa ttgggaaaat taaagcgtac aagtggctat cacgcggata
     1021 tgaggtatat gtcaaagatt tgaaattctc cagcatgaaa taccttaata caaatagtga
     1081 tgtgttggat gatttatcac gacaatattt tactattgag atttgtactc cgacaaatca
     1141 ccaccttacg ctattgaaaa ccgttataac aaggtatgtc tattcttata ttagcattga
     1201 aaaaccactg tgtaacaggt tagaagattt agaagaaatg aagtcgctag tagaaagtca
     1261 cccacatcta gcaaaaaaaa tgtttgccag tgaacaatac ttcttttcga aaattttgga
     1321 aaaactgtta caagtagatt gtttctctct agataaaatc aaggaaataa cagttaattt
     1381 ttctaaagat aggattgagg ataacgagaa tgggagattt ttagataaag agatattggg
     1441 ctatggaata gagattcctc atatcattgc tgtcatttct tatttaggaa tatcattaga
     1501 agaattcaaa aaaggaatct ttgtgaatgc tatttatata aaagacttag agaaacacg
//
LOCUS       DAUGUF010000084         1435 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.084, whole genome shotgun sequence.
ACCESSION   DAUGUF010000084 DAUGUF010000000
VERSION     DAUGUF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1435
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.084"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..819
                     /locus_tag="VIB71_001713"
     CDS             <1..819
                     /locus_tag="VIB71_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ8823418.1"
                     /translation="INSNQQLIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLI
                     EHSDTLLIHAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSN
                     SGILLTYAGTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGI
                     RTCNFSTEISKIYYIKTDKKEKQIYHSIWNDSLASLYLNELLGRHISGQVACFQSDNG
                     KYFSTMPLINYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            874..>1435
                     /locus_tag="VIB71_001714"
     CDS             874..>1435
                     /locus_tag="VIB71_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ8823419.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFL"
BASE COUNT          526 a          169 c          267 g          473 t
ORIGIN      
        1 attaacagca atcagcaact tatagaatat gatggcaatg gaaatatttt agtttatgga
       61 agattaaagt attttaaaga aggaatttca ttatactaca ttggagagta cttagctgaa
      121 tgtctcttga ttgaacatag tgacacctta ttaattcacg cagcagcagt ttataatcct
      181 ttatctggcc attcaatttt actattagga gataaaggtg ctggaaaaac tacggttgca
      241 ataaggctgt gtatagaaca tgggtatcac cttattggta atgaccaagt aatatttggt
      301 tcgaactctg gaatactact aacttatgca gggacatctt tctttaaaat aagaaggaca
      361 gctgttttgt cggacaattt actgtttaaa ttatttagca aattttttaa ccgttcatta
      421 caatttaata aggcaagttg ggatgataaa atttcaattt tcccaaagga gttgggaata
      481 cgaacttgta atttttctac tgaaatctca aaaatttatt atataaagac agacaagaaa
      541 gaaaagcaaa tttatcattc aatttggaat gatagtttag caagtttata tctaaatgag
      601 ctattgggaa ggcatatttc tggacaggtt gcatgttttc aatcagataa tggaaaatat
      661 ttttctacaa tgcctttgat aaattatgaa aaaaataatc gggtacgaga acagatagtg
      721 aagggtattt tcgctaaaca aaaattattt aaaattacag cagctacgcc agctaagatt
      781 gcagaagcga ttatagaaaa tgttaagaaa aactcatagt gtgtgtgaat ttggggatta
      841 atatgaagta ttgaaaaagg agtaagagta attatgtttg tgataggcat tccaacttta
      901 aatgaggcag ataatatcag tagattagtt aaacaaattg atgagtatgc tgtaaattta
      961 gggaaagaaa ttattattat taattcggat agtaaaagta cagatggaac tccgcagatt
     1021 tttttagaaa ccaaaactta taacaccaaa gtttcgatag tatcagaagc taaaggaaaa
     1081 ggttataatg tgagaaatat tttcgaatat gcaataaatc atgtgccgaa tttctccggt
     1141 ttaattttga ttgatggaga cgttgtctca atgaaaaaaa tgtggttaga aaagatgttt
     1201 atagcaattg aatctggaaa tgatcttata atcccaaatt atgctagaaa atcttttgaa
     1261 ggaaatgcga caaaccattt tatttatccc atgttagtga aatttttcaa acgtgatatg
     1321 ccttatcaat gcatctctgg tgattttgga ttttcaagag gattgataaa agatttaact
     1381 ttgaagtgta attggcacaa atatacatta ggttacggga tagatatttt tttaa
//
LOCUS       DAUGUF010000085         1420 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUGUF010000085 DAUGUF010000000
VERSION     DAUGUF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.085"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            264..380
                     /locus_tag="VIB71_001715"
                     /pseudo
     CDS             264..380
                     /locus_tag="VIB71_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611996.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(566..>1420)
                     /locus_tag="VIB71_001716"
     CDS             complement(566..>1420)
                     /locus_tag="VIB71_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ8823420.1"
                     /translation="EREAAKVREAIANDPTLTKADKAKQTEAVAKALKAAIAAVDKAT
                     TAEGINQELGKGITAINKAYRPGEGVKARKEAAKANLEKVAKETKALISGDRYLSETE
                     KAAQKQAVEQALAKALGQVEAAKTVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAAL
                     NEAKQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIA
                     SVKEAKDKGITAIRAAYVPNKAVAKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLY
                     SKKKESKD"
BASE COUNT          402 a          294 c          254 g          470 t
ORIGIN      
        1 atcaagtaga aatgtcttta ttaagcgaat caatcaaggt tgtagagtaa atgctggact
       61 agatttcatg tagaaattag taaaagttag gagatttttt ggtcgtttca aacgataaca
      121 tcatcttctt ataacaagaa cttcactcag agataaacta ttctcatact ttagtagcct
      181 cttttgagct tgtagcacga aaattcgctc gaactgattt aaaataggca ttttatctgc
      241 tcgcttgatc cctactgcgc aaccaagaaa ccttttattc actagaacaa ttaaccctta
      301 aaaccaagga ggaagtccac tggtggaact accatcacct tcacagtaat cttaattatc
      361 aaacacctat aactaaatga gtcatcgttt gaacaaaaaa cgccttataa attctgtaca
      421 gaaaactgtt gccttttcaa ttgaactttg aaatgttttc aatacactcc gttcttgagc
      481 ccttacgatc caaaaaacca aggtgatttc aaaatcacct tggtttgaaa atatagtaga
      541 aagcaatttg gataaagcca ggttcttagt ctttactttc ttttttcttg ctataaagca
      601 ccatacctaa aagaagagac ataactccta agccaacaag aacaattgag tttgcatcac
      661 ctgattttgg aagatggttc gctgacgatg attttgcgac tgccttatta ggcacatagg
      721 ctgcacggat agcagtaata cctttatctt ttgcttcttt cacagacgca atagattgtg
      781 ctgaacgaac agtcgcaata gccgtcttaa gcgctaatga tacattttct gattgttcag
      841 ctttttgagc ttcagtcaat ttagcatcag ttgtaatctt agcaagtgtt tctgccgcag
      901 cttgtttaag agcttcaata gcagcttgtt tcgcttcgtt aagagcagct gttgcttgat
      961 cagtatcttt agctaaacca gcaacatatg ctgaacggat agctacagta ccaaggtttt
     1021 ctgccaactt aacagcttca actgtcttag cagcctcaac ttgaccaagt gctttcgcaa
     1081 gagcttgctc aacagcttgt ttttgggctg ctttttcagt ttcgctcaag taacggtctc
     1141 ctgaaataag agctttagtt tctttagcta ctttttcaag attagcttta gcagcttctt
     1201 tacgtgcttt aacaccttca cctggacggt aagctttgtt gatagctgtg atgcctttac
     1261 caagttcttg gttaatgcct tcagctgttg tcgctttatc aaccgctgcg atagcagctt
     1321 taagagcttt agcaacagct tctgtttgtt tagctttatc agcttttgtt aaggttgggt
     1381 cgttagcgat agcttcacga accttagcag cttctctttc
//
LOCUS       DAUGUF010000086         1413 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUGUF010000086 DAUGUF010000000
VERSION     DAUGUF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1413
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.086"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(85..1206)
                     /gene="mnmA"
                     /locus_tag="VIB71_001717"
     CDS             complement(85..1206)
                     /gene="mnmA"
                     /locus_tag="VIB71_001717"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEQ8823421.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVTVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          429 a          309 c          238 g          437 t
ORIGIN      
        1 catgattggt ttttataaat aatatcatat gatgtcaaag gaattgttga atgtcccttt
       61 ctttttatct taataaaagg ttcattaaat gtactgacaa ggctgcccat ttttataagc
      121 catgtcaatc ataccaccac caaggcattc ttttccgtca tagaaaacaa cagcttgacc
      181 aggagtaatc gcgcgctgtg gctctgcaaa aacaacttct gccttatctc ctcgaacatg
      241 caccgtcacg tgtgaatcgg gttgacgata gcgaaattta gcagtacatt caaatgtgaa
      301 ctcttctggc atctcacgtg taaaatggat gactgaggcg tcaagactat ttgacattag
      361 ggcttcatgg tagaaacctt gaccaacgta taaaatattt tgcgacaaat ctttaccgac
      421 aacaaaccaa ggttgattat ccccaccatg ctgaccacca atgcccagac caccacgctg
      481 accaatagta taatacataa ggccggcatg ttctcccata tcgcgaccat caatagtcat
      541 catgcgacct ttttgtgccg gtaagtactg gctcaaaaac tgtttgaaat tcttttcacc
      601 aataaaacaa atacctgttg aatctttctt tttagccgtt gcaagccctg ctcgctcagc
      661 gatttctcta acttctgact tttgcaaatg accaaggggg aataaagtct tttgtagttg
      721 ttcctgtgat agttgactta aaaagtaggt ttggtctttg ccattatcag ctccacgtaa
      781 catgtgaacc gtaccatttt catcacgctt gacttgagca tagtgtcccg ttgctacata
      841 atctgcacct aaagtcatgg catagtcaag gaaagcttta aattttattt ccttattaca
      901 catgacatcg ggatttggag tacgacctgc tcggtattcg gccaagaaat attcaaatac
      961 tctgtcccaa tattcttttt caaaattgac tgaatagtaa ggaataccga tttgatcagc
     1021 aacggctgct acatctttgt aatcttcagt agctgtgcaa acaccaaatt catctgtatc
     1081 gtcccagttt ttcatgaaga caccaataac atcataacct tgctccttta aaagtagagc
     1141 tgttacagat gaatcaacgc caccactcat accaacgaca acacgtatct ttgagttatc
     1201 tgtcataaaa aattctccca tcaataataa gatagaaaaa gataatcatc atattatgaa
     1261 tattatgatt ctttttctta tcagttaacg tacgattgaa ggtcgtcgtt ttcaaaagtc
     1321 gatttgaagg tcgattttga agcgccatca gcgcaaacct tattataaca attactgcgt
     1381 ggaatgccaa tcattttatt gctcaataat ttt
//
LOCUS       DAUGUF010000087         1278 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUGUF010000087 DAUGUF010000000
VERSION     DAUGUF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.087"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..>1278
                     /locus_tag="VIB71_001718"
     CDS             <1..>1278
                     /locus_tag="VIB71_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ8823422.1"
                     /translation="TISLFSFRNSQIPSTFISAFILIFSLLESGLNTYYQLQGINKEW
                     GFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDSMKFNYYGISQFSSVR
                     NRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSEGPPNKFGFTKLKTSG
                     NTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSGKSLTYFNLQPAQLIS
                     GANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIFSNPDAKEMRIQTDNH
                     NFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHFYSLSIESYLEAMNSI
                     KQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGKNLPVKKAQGGFLSVT
                     IPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLL"
BASE COUNT          444 a          235 c          171 g          428 t
ORIGIN      
        1 actatttcac tattttcgtt tagaaattct caaatcccat ctacttttat ttctgctttc
       61 atacttatct ttagccttct tgaatcaggg ttaaacacct actaccagct tcaaggaatt
      121 aataaggagt ggggattccc atcacgacag atatataata gtcaattaaa ggatattaac
      181 aaccttgtca actctgtgtc aaaaaatagt caaccttttt ttagaatgga aaggctactt
      241 ccccaaacag ggaacgatag catgaaattt aattattacg gcatttcaca attttcctct
      301 gtaagaaata gactatctag ttctttattg gatcgattgg gatttcagtc taaaggcaca
      361 aatttaaacc ttagatacca aaacaatact attattatgg acagtctact tggtataaaa
      421 tataatctta gcgaaggacc tccaaataaa tttggattta caaaactaaa aactagcggg
      481 aatactactc tttatcaaaa tcactatagt agccctttag ctatattaac acgtaatgtt
      541 tacaaagatg tcaacctaaa tgtcaatacc cttgataacc aaaccaaatt acttaaccaa
      601 ctaagtggga aatctttaac ctattttaac ttacagccag ctcaacttat ttctggtgct
      661 aatcaattta acggacaaat atctgcacaa gcttctgatt atcaaaactc cgttaccctt
      721 aattatcaaa ttaacatccc taaacatagt caactctatg ttagcatacc caatattata
      781 ttttcaaatc ctgatgctaa agagatgcgt attcagacag ataatcataa tttcatatat
      841 actacagata acgcttactc tttttttgat ttaggatatt tcgccgatgc caaagttgct
      901 acattttcgt ttgtttttcc aaaaaataaa caaattagtt ttaaggaacc tcatttttat
      961 agtttgtcta ttgaatctta ccttgaagca atgaatagca ttaaacaaaa aaatgttcat
     1021 acttacgcta aaagtaatac ggtaatcact gattataatt caaaaacgaa aggttctctt
     1081 atttttacac ttccttacga taaaggttgg tcagcacaaa aagatgggaa aaatcttcca
     1141 gtcaaaaaag cacaaggagg atttctatca gttactattc ctaaaggaaa gggacgtgtt
     1201 atccttacct ttattcctaa tggttttaaa ttagggttat ctctatcttg tgtaggaatt
     1261 atcgcttata tgcttttg
//
LOCUS       DAUGUF010000088         1266 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUGUF010000088 DAUGUF010000000
VERSION     DAUGUF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.088"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     misc_feature    12..147
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            176..676
                     /locus_tag="VIB71_001719"
     CDS             176..676
                     /locus_tag="VIB71_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEQ8823423.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            741..1106
                     /gene="rplL"
                     /locus_tag="VIB71_001720"
     CDS             741..1106
                     /gene="rplL"
                     /locus_tag="VIB71_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEQ8823424.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKSKLEEAGATITLK"
BASE COUNT          416 a          220 c          272 g          358 t
ORIGIN      
        1 taatgatata ggttttgata aaaaactgac ctaagacagc aggggagcat gctcataata
       61 ttcctgccga ggcacaaaac gtgattaaag aaaataacgt atttgtactt tcgtgtctag
      121 gtttaggtgc gatttttttg tacctagccc aaaaataaaa acggaggtaa aactaatgag
      181 tgaagcaatt attgctaaaa aagctgaaca agtcgaactt attgctgaga aaatgaaagc
      241 agcagcaagt atcgttgttg ttgattcacg tggtcttaca gttgatcaag atactgttct
      301 tcgtcgttca cttcgtgaaa gtggcgttga gttcaaagtt atcaaaaact caattttgac
      361 tcgtgcagct gaaaaagcag gtcttgatga gttgaaagat gtattcgtag gaccatctgc
      421 agtagcattt tctaacgaag atgttatcgc accagctaaa gttatcaacg actttactaa
      481 aactgctgac gcacttgaaa tcaaaggtgg tgcaatcgaa ggcgctgttt cttcaaaaga
      541 agaaatccaa gcacttgcaa cattgccaaa ccgcgaagga atgctttcta tgcttctttc
      601 tgtacttcaa gctccagtcc gcaacgttgc atacgctgtc aaagctgttg cagaaaacaa
      661 agaaggcgct gcttaagacg tctcagagta gcttaaggct acgcttaaca ttttaaatta
      721 attatttgga ggaaatcaca atggcattga acattgaaaa cattattgct gaaattaaag
      781 aagcttcaat ccttgagctt aacgatcttg taaaagctat cgaagaagaa tttggtgtaa
      841 ctgcagctgc tcctgtagct gctgcagctg ctggtggtgc tgaagaagct gctaaagatt
      901 cattcgacgt tgaattgaca tctgctggcg acaaaaaagt tggcgttatc aaagctgttc
      961 gtgaaatcac aggtcttggt cttaaagaag ctaaaggtct tgttgatgga gcacctgcta
     1021 acgttaaaga aggcgttgct gctgcagaag ctgaagaaat caaatctaaa cttgaagaag
     1081 ctggagcaac aatcactctt aaataagaag cagatagcaa tttgagagcg aaatcccgat
     1141 ttatcagtct tttagagctt atagcgattt gaagaaactg ataaaatgat ttggtttttt
     1201 gccaaaaatc ctgccaaaaa aatctttggc aggattttta ttttctataa aaattaagct
     1261 gagtag
//
LOCUS       DAUGUF010000089         1226 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUGUF010000089 DAUGUF010000000
VERSION     DAUGUF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1226
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.089"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            128..>1226
                     /locus_tag="VIB71_001721"
     CDS             128..>1226
                     /locus_tag="VIB71_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ8823425.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNKNII"
BASE COUNT          445 a          187 c          193 g          401 t
ORIGIN      
        1 tattgtagaa aactatattt tactaacact agaatcccga caattaagtc aaaaaaagtt
       61 atcactcacc taacctgaat aaaaatggta taatcgtaag gatcacacta tttattaagg
      121 aaacattatg aaaattgttc agggagtaca acttcatctg attaagacca aacagtttaa
      181 aaccaatcat attacctttc gtttttcagg tgatttgaac caaaaaacag tagcaaaaag
      241 agtcttagtg gcacagatgt tagcaacagc taatgagtgt tatccaactg ttaggcagtt
      301 tagagaaaaa ttagcacgac tttatggagc tagcttgtca actaacgtgt taacaaaagg
      361 gttagttcat attgtggata tcgatattac ttttattcaa gatagatatg cttgcaatgg
      421 ggaaaaaata ctagatgaaa tgattcagtt tttaaaagat atcttgttct cacccctatt
      481 atccatcgcc cagtatcagc ctaaagtttt tgagactgaa aaaaataatt tgattaacta
      541 catcgagtca gatagagagg attcttttta ctacagctct cttaaggtaa aagaattgtt
      601 ttattgtaat aagaatctac aaatgtcaga atatggtagc ccagaactaa ttgcaaaaga
      661 gactgcctat actagctatc aagaatttca taaaatgctc aatgaagatc agattgatat
      721 tttcatttta ggagattttg atgattatcg cgttgttcag ctaattcatc aatttccact
      781 tgataaccga aataaaaacc taaatttctt tcatttacaa aattctgtca atattattaa
      841 agaatctatt gaaaaaagag cagttcatca atctatttta caattagctt atcacttccc
      901 ttcagttttt ggacaacgtg actattatgc tttagttctt ttaaatgggt tgttaggctc
      961 ttttgcacat tcccgtctct ttataaaaat tagagaagaa gaaggacttg cttatagtat
     1021 agggtgtcgt tttgatagtt atacaggatt atttgaaatt tatactggaa ttgacagtca
     1081 acatcgcact aaaacgttac aactaatcat ccaagaatta aatgccatta aaatgggacg
     1141 attctcagaa caattgatta aaaagaccag atcgatgttg ttgaataatg ccttattatc
     1201 agaagattat aataaaaata taattg
//
LOCUS       DAUGUF010000090         1132 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUGUF010000090 DAUGUF010000000
VERSION     DAUGUF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1132
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.090"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..>1132)
                     /locus_tag="VIB71_001722"
     CDS             complement(<1..>1132)
                     /locus_tag="VIB71_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ8823426.1"
                     /translation="KTILASDAFHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYAL
                     MCYYLGSFFSPLLFFFNLTSMPDAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMIS
                     ISVFYSLMSFLTSQMELNSWLDVFILLPLVILGLNKLITENKTRTYYLSISLLFIQNY
                     YFGYMIALFCILYALVCLLRLNDFNKMFIAFVRFTAVSICAALTSALVILPTYLDLST
                     YGENLSPIKQLVTNNAWFLDIPAKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLE
                     SIPLKIKLANACLLTFIIISFYLQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACET
                     LSRLKEVTQIKAGFAFIFLIILTSLPYSFSQQYNFLPLTLFLL"
BASE COUNT          469 a          156 c          204 g          303 t
ORIGIN      
        1 aagtaaaaaa agagttaaag gtagaaaatt atattgttga gaaaagctat aaggaagaga
       61 tgtcagtata atgaggaaaa taaaagcaaa acctgctttt atttgagtca cttcttttag
      121 tcgagagaga gtctcacatg cgagtaatag gataactatg gaaaaagacc aagcgtagcg
      181 atgcaaaaac atatttggtg agtgcatccc ctgccaaaaa agatcaagtg gctgtaggta
      241 aaaacttatt ataataaaag ttaacaagca ggcattggct aattttattt ttaaagggat
      301 actttctaaa gtaaaataaa taacactaag cattagggga aataatccta cgtaaatcat
      361 aggcagagca ttaaacttgg tagtatcgta cactcctatt gagagcttag caggtatatc
      421 caaaaaccaa gcattgttcg taactaactg ttttatcggg gatagattct ctccataagt
      481 tgacaaatct agataggtag gaagtattac tagagcactt gttaaagcag cacatattga
      541 cacagctgta aacctaacaa aagcgataaa cattttgtta aaatcattga gacgtaaaag
      601 acaaactaag gcgtaaagaa tacaaaaaag agcaatcatg tagccaaagt agtaattttg
      661 aatgaataat aatgatatcg aaagataata agttctggtt ttattttctg tgataagttt
      721 atttaatcca agtataacaa gtggaagaag aatgaaaaca tctaaccaag aatttagttc
      781 catttgactt gtcaagaagc tcattaagct ataaaaaact gagatggaaa tcatcaagaa
      841 agcactgatt tttggatata atctatgaaa agaatagcat gcagctaatc ctattaaccc
      901 aaattttatc aaggtaaaca aatagatagc atctggcata gaggttaaat taaaaaagaa
      961 aagtaatgga gaaaagaaac tgccaagata ataacacatt aaagcataaa aatttatccc
     1021 tagtccgctt gtaaaggtat aaaaaaaact atcagaaccg tgcatgatgt tacgaaagtt
     1081 ctgcgcaaaa ataacatact gatgaaaagc atcactagct agaattgttt ta
//
LOCUS       DAUGUF010000091         1129 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUGUF010000091 DAUGUF010000000
VERSION     DAUGUF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1129
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.091"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..529
                     /locus_tag="VIB71_001723"
     CDS             <1..529
                     /locus_tag="VIB71_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEQ8823427.1"
                     /translation="ISVFEGYFNSLISYTRMLSEDRSVKLILVEKLLSELHFEVDDLL
                     NINNIEFSICNRLIITSFYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGEQI
                     HFEIWNNGERFSDSTLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLNNP
                     ARGGASAIISIKKKI"
     gene            686..826
                     /locus_tag="VIB71_001724"
     CDS             686..826
                     /locus_tag="VIB71_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEQ8823428.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     VK"
BASE COUNT          399 a          147 c          195 g          388 t
ORIGIN      
        1 tatttctgtt tttgaaggct atttcaattc tttaatatct tatacacgca tgctttcaga
       61 ggatagatca gtgaaactaa ttttagttga gaagctatta agtgagttac attttgaagt
      121 cgatgactta ttgaatatca ataatattga attttctatt tgtaatagac ttattatcac
      181 ttctttttat ggagatgagg aaaatctgat aagagctctt tctaaccttt tagttaatgc
      241 aataagattt atgcccgtat tagataaaaa aatcgaagtt atactgtctg agtcaggaga
      301 gcaaattcat tttgaaatat ggaataatgg tgagcgtttc agtgatagta cactgaaaaa
      361 gggagataaa ttattttaca cggaagatta tagcagaggt aacaaacatt atggaatcgg
      421 tttggcattt gttaaaggcg ttgctatcaa acacggtggg aatcttcaat tgaataatcc
      481 agctagagga ggtgctagcg ccataatctc gataaaaaag aaaatttaat agatttgatt
      541 gaaactggag tatttcaggc aaaaaatcgt aaatttttgt gatttttggc taaaatactt
      601 tttttctgaa caaattctga acttggggtg tcataataat catgtaaata tatcggatgc
      661 aaaaacgtaa gagaggaact agaaaatgaa taacacaatt aaagactttg atctcgattt
      721 gaaaacaaat aaaaaagaca ctgctacacc ttatgttggt agccgttacc tatgtacccc
      781 tggttcttgt tggaaattag tttgctttac aacaactgtt aaataataaa gttatcatta
      841 tcatcaacat tataatttca aataatttga tatatttata aatttagggg agtagactga
      901 ttttagtttg ctcctttatt agtagataag gaagttatac atgattaaag ctcagctaaa
      961 gaatctaata aaaacaattc atctcgtaaa agaggctggt ttctccctac tggtgttctc
     1021 aattgctatt agcttatttc aagggatttt acccattttt agtatgctac tagttcaaaa
     1081 aatgttaaac attataacga ctgatataaa aaattttcac acattgatg
//
LOCUS       DAUGUF010000092         1080 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUGUF010000092 DAUGUF010000000
VERSION     DAUGUF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.092"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            166..447
                     /locus_tag="VIB71_001725"
     CDS             166..447
                     /locus_tag="VIB71_001725"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8823429.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(924..1011)
                     /locus_tag="VIB71_001726"
     tRNA            complement(924..1011)
                     /locus_tag="VIB71_001726"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(975..977),aa:Ser,seq:gct)
BASE COUNT          363 a          238 c          132 g          347 t
ORIGIN      
        1 acaaaattgt ttatcttcac tcagacacct tatccttctt agaatgaatt tttagttact
       61 tatccacagg ttaataactt tttttcgcct aaaatattat ccacaatagt gacattttct
      121 attatcagtt atagtataat ttcattagga atctaaaacc ttagcatcac ggttttaaat
      181 tatgtaaatg ctggggacgc aaaaagcatt cataatcatc tctttcatta taccagacag
      241 gtgagaaggc atgtcaaagt tattaccata ggcatactca gtgcccacta ctatgagatt
      301 actatgcttt ttctacaggc taaaattatc ctcgattgtt ttcatatccc ccaacgtctt
      361 agacaagcta taactcgctt tcgtatccga atcataaata cttctgctat aaaacctatc
      421 gcgtatagaa ctctcaaact ttactgaaaa ctcatacagc atgattcacg gaagctcatc
      481 aataatagct ttattgccca atttttcgta cgcccataac taacatctag aaaagaaaag
      541 ctcttactca caagatctct gaatttcaat aattattcct aactctatca actcttgctc
      601 ttcccatttt tcagacaatt tttaaaattt ttctaaaaga aaagaaaaca agattagcaa
      661 tatacttaaa ctcaactact ctaaggccaa attagaaaca gtcaacaacc ttatcaaagc
      721 catcaagtta aacgttttac tcctctacag tagtcaaaga gcctatcatt ttagttatcg
      781 aaataatgaa cgatttaaat attctattta gttggttttg aagattacaa aaaaaagacg
      841 ataaccgtct tctttccccc ttatttataa ttcatccttt aatatgtttc atttaacata
      901 ttaaccaaaa tatctttaca aaacggagaa taagggattc gaacccttgc gccagttacc
      961 cgacctaacg atttagcaaa ccgtcctctt cagcctcttg agtaattctc caaatatata
     1021 tgggcacgag tggactcgaa ccaccgacct cacgcttatc aggcgtgcgc tctaaccacc
//
LOCUS       DAUGUF010000093          945 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUGUF010000093 DAUGUF010000000
VERSION     DAUGUF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.093"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            139..618
                     /gene="rlmH"
                     /locus_tag="VIB71_001727"
     CDS             139..618
                     /gene="rlmH"
                     /locus_tag="VIB71_001727"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEQ8823430.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            complement(775..848)
                     /locus_tag="VIB71_001728"
     tRNA            complement(775..848)
                     /locus_tag="VIB71_001728"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(812..814),aa:Arg,seq:tct)
BASE COUNT          348 a          136 c          159 g          302 t
ORIGIN      
        1 aaagtaatcc acagcctgtg gattactttt ctttttacta ataaagacct ttgtacaaag
       61 gtttttatta gtagttgaag aaaaataact tgtggataaa ttgtgtaaaa agtaatgttc
      121 ttgtgataca attaagctat gaaagtgaaa ctaatttgtg ttggaaaact aaaagaaaga
      181 tacctcaaag atggtatttc agaatatcaa aaaagacttt cccgtttttg tcaattcgaa
      241 atgattgagt taactgatga aagaacacca gataaagcaa gttttgctga taatcaattg
      301 attatgagta aagaagctca gcgaatccat aaaaaaattg gggaacgtga ttttgtaatt
      361 gcattagcta ttgaaggaaa acagtttcct tcagagacat ttagtgaatt aatatcaggg
      421 gttactgtta agggatattc aactatcacg tttattattg gtgggagtct tggattagat
      481 tcaattatta aaaaaagagc taatatgcta atgagttttg gattgttaac cttacctcat
      541 cagttaatgc gtctagtcct tactgagcaa atttatcgtg cttttatgat tacacaaggc
      601 agtccttatc ataagtaaga gagtgtgaac tggaataact aactcttacc actttattag
      661 ataatagttc ggtataatta aaagcaaata ttaaaaaaag acgtactaaa tcctatcttt
      721 tcaatacact aaggtaaata caaaaaaagc actaaaacag tgctttttta tctttgatcc
      781 cagcaggatt cgaacctgcg accgttcgct tagaaggcga atgctctatc cagctgagct
      841 atgagacctt aaccacatca ttttaacaaa aattatctaa aactgtcaat atttattttg
      901 aaaaaactag aaaataacat tatatcccgc gttataaaat gaagt
//
LOCUS       DAUGUF010000094          943 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUGUF010000094 DAUGUF010000000
VERSION     DAUGUF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.094"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            13..777
                     /locus_tag="VIB71_001729"
                     /pseudo
     CDS             13..777
                     /locus_tag="VIB71_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          315 a          192 c          175 g          261 t
ORIGIN      
        1 aagcagatga acatgtctaa tattaattct accagaaaat catcctattc tcatctttca
       61 gccacagaac ggggtgaaat tgctgcttat cttaaaatgg gaaagaaacc cgttgagatt
      121 gctcgactcc tgggtcgtca ccgttctaca atctgccgag aaataaaacg tggttcagta
      181 gatcaggtaa aggataagaa tggaaaacaa accttcttca acgcctattt cgctgatagt
      241 gggcaacgtg tctattaaac caatcgattt gactaagatg gttagtatca gaaaacgttc
      301 taagaaagtc atgaagacga ataagaagac tttaggtaaa tctatcgaag aacgtccaga
      361 atatattaat gatcgttctg aatttgggca ttgggagatt gatttggctc tcggcaagaa
      421 aaccaaaagt gaagctgtta tgttgacttt ggtagagcgc cagacacgct atgcactata
      481 gaagacaagc agtcccaaac cattaaccgt gctgtcacgc atctcatcag tcagtatcct
      541 attgcatcca tcacagcgga taatggttct gagtttagtt tactctcaga cttaaaagct
      601 gttgacgttt actttgcaca tccctattct tcacatgaga gaggaacaaa cgagaacttc
      661 aatggtctcc tcagagaata tgtccctaaa ggaatctcac ttaatccact aacctctgaa
      721 gaacttgaca atgatattac tgccatcaat gagcgcctaa gacgacttct tcaatagcaa
      781 tcctcaaaat tcctgtttga gctatcccga acagcttaac ctctggaact ctagttatct
      841 atgaactcgt tgcacttgac ttgacaactt gcggtttaaa aaaaatcaaa ttttttttaa
      901 aaaagtatag acaaaaaaaa tcaatctgct ataatagtaa gag
//
LOCUS       DAUGUF010000095          890 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUGUF010000095 DAUGUF010000000
VERSION     DAUGUF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.095"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..>890
                     /locus_tag="VIB71_001730"
     CDS             <1..>890
                     /locus_tag="VIB71_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEQ8823431.1"
                     /translation="EAAINKLLCKAKNINATSSEELAYKDATFIILSLPTNLKVNKLD
                     TSIIEISVSNILKINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHD
                     QLYPSRTIVGNESRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIA
                     FFNELDTFAEMQNLDSKKIIEAMGYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKE
                     IPAPIITSISESNLLRKIHIAKMILNSSAKTIGIYRINSKKDSDNCRESSTIDVAKLL
                     KSSGKDVIIFEPLINQKKFL"
BASE COUNT          327 a          131 c          144 g          288 t
ORIGIN      
        1 aagaagcagc tataaacaaa cttttatgta aggcaaaaaa tattaatgca acttcttctg
       61 aagaattagc atataaggat gcgactttca taatcttgtc tttgccaacc aacctaaaag
      121 ttaataagct tgatacttcc attatcgaaa tttctgtaag taatatttta aagataaaca
      181 aaaaggctac aattgtaata aagtcgacag ttccaattgg ttttacagaa tatttaagga
      241 atcgatttca ctacaacgat atcatttttt cacctgagtt ccttagggaa ggatcaacta
      301 ttcatgatca attgtatcct tcgagaacta tagttggaaa tgaatctaga aattctcaat
      361 tattcttaga catactaaca gatatatcgg ttgaaaaaga ctcgccatct ttattagttg
      421 gctcttctga agcagaagcg ataaagttat tttcgaatgc atacttggca caaaaaattg
      481 ctttttttaa tgagttggat acgtttgctg aaatgcaaaa tttggactca aaaaaaatta
      541 ttgaggctat gggatatgac cagagaatag gaaattcgca caataatcct tctttcggtt
      601 ttggtgggta ctgtcttcct aaggatatta agcaattaga gtatcatttt aaagaaattc
      661 cagcaccaat tattaccagt ataagtgagt ctaatttatt aagaaaaatt catatagcaa
      721 aaatgatttt gaacagctca gctaaaacaa taggaattta tagaattaat tccaaaaaag
      781 attcggataa ttgtagggaa tcttctacaa ttgatgttgc taaacttcta aaaagcagtg
      841 gtaaggatgt tatcatcttt gagcccttaa ttaaccaaaa aaagtttttg
//
LOCUS       DAUGUF010000096          873 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUGUF010000096 DAUGUF010000000
VERSION     DAUGUF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.096"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            58..744
                     /locus_tag="VIB71_001731"
     CDS             58..744
                     /locus_tag="VIB71_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ8823432.1"
                     /translation="MYKILAIDDDKEILKLMKTSLEIENYHVITCQEIELPIVFDDFK
                     GYDLILLYIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
BASE COUNT          302 a          104 c          166 g          301 t
ORIGIN      
        1 ccgcttacat tgagaatagt ttatttgtaa gtatttcatt atttaaaagg ggtaataatg
       61 tataagattt tagccataga tgatgataaa gaaattctga agcttatgaa gacttctttg
      121 gagattgaaa attaccatgt tataacctgt caagagatag aattacctat agtttttgat
      181 gattttaaag gatatgattt gatcttattg tatatcatga tgcctaatat aagtggaact
      241 gagttttgtt ataaaattcg ggaagaagtt cattctccaa ttatttttgt tagcgcttta
      301 gatggcgata atgaaattgt ccaagcttta aatatagggg gagacgattt tattgtgaaa
      361 ccatttagct taaaacaatt cgtagctaaa gttaactctc atttgaagag agaagagaga
      421 gcaaagataa agaatgaggc tgaggagaga gtgaagcgca gttttccacc tatagaaatc
      481 tatctagagg aacgtatgtt atatattgat aaacagccgt tattcctgac ttatagagag
      541 tacgaaattt tagaattact gtcacgtcat ccgtataaag ttttcacaaa agaagagata
      601 tatgaacaag tatatagcga tgaagcttca gcattgtttc attctatttc agaatatatc
      661 tatcagatta gaatgaaatt ttcaagtttt ggaattaatc caataaaaac tattcgcggg
      721 attggttata aatgggatgt ttaaaaaata ttcaataaaa aatcgtgttt ggcgcgccgt
      781 cgttgaaatt gtctttggag tttgtatcac tgttttaatg attgcgataa tatcgctttc
      841 tttttcaaag ttaaatatag tgacatctca taa
//
LOCUS       DAUGUF010000097          862 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUGUF010000097 DAUGUF010000000
VERSION     DAUGUF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.097"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            185..>862
                     /locus_tag="VIB71_001732"
     CDS             185..>862
                     /locus_tag="VIB71_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ8823433.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESAILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIVLEKEYDGSENLEEL
                     FNNQILFE"
BASE COUNT          321 a          104 c          164 g          273 t
ORIGIN      
        1 aagagtataa tcgatttggt ggtacaaatg atatctataa tactaaattc aatttagtag
       61 gaagtttttt acatctatca atgaatcgat taaacgggat tgatagagag tttgaagaga
      121 aagtgtattg ttttgcttac tatacactaa acgctcagca atatatagaa tgggagtaac
      181 taatatgttg aaaatacaaa atctaaaaaa atcttatggt aagagaacca tattgaataa
      241 tgtcaatatg aatattccta agggaaaagt gtatgcttta atcggtccaa atggtgctgg
      301 aaaatcaact attatgaaaa ttttgacagg cttagttagt aagacaagtg gttctattat
      361 ttttgaaggt agagaatggt cacgtcggga tctgcgaaaa atcgggagta ttattgaaga
      421 accaccactt tataaaaatt tgagtgctta cgataatatg aaggtagtta caacaatgct
      481 tggtgtttca gaaagcgcta tacttccatt attaaataaa gttggtctag gaaatattga
      541 caagagacca gtaaaacaat tttctcttgg aatgaagcaa cggttaggta tagctatctc
      601 tttaataaat tcacctaaat tacttatatt agacgaacct actaatggct tggacccaat
      661 tggaattcaa gaattaaggg aaattataga gtcatttaaa tcagaaggaa tgacaattat
      721 gatttcaagc catatactgt cagaagttga acatctagct gattttattg gatttatcta
      781 tgaaggaaag attgttctgg aaaaagaata tgacggctct gagaatcttg aagagttatt
      841 caataatcaa attttatttg aa
//
LOCUS       DAUGUF010000098          813 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUGUF010000098 DAUGUF010000000
VERSION     DAUGUF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.098"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            44..802
                     /gene="mf2"
                     /locus_tag="VIB71_001733"
     CDS             44..802
                     /gene="mf2"
                     /locus_tag="VIB71_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNase Mf2"
                     /protein_id="HEQ8823434.1"
                     /translation="MKLSKQKASLLTAVLLLLSLSITTITVDAARVRTYPNVSHANTH
                     YKNTVSSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHETKDVRTKINYDPVGWHN
                     YQFPYGDGSKSSWVMNRGHLVGYQFCGLNDEPRNLVAMTAWLNTGAYSGANDSNPEGM
                     LYYENRLDSWLALHPDFWLDYKVTPIYSGNEVVPRQIELQYVGIDSSGELLTIRLNSN
                     KESIDENGVTTVILENSAPNINLDYLNGTATPKN"
BASE COUNT          276 a          150 c          145 g          242 t
ORIGIN      
        1 gatccactct aaaagctaaa aatggaaagg tttaggtgtt atcatgaaat tatctaaaca
       61 aaaggcaagt ttgcttaccg ctgttttact gttactttct ctttctataa cgacaataac
      121 tgttgacgca gctagggtac gaacttatcc gaatgtatcc catgcaaaca cacattataa
      181 aaatactgtt tctagtaagc tcttaccttt tactgctaat tatcagttac aacttggtga
      241 gttggataac cttaaccgcg ctaccttttc acatatccaa ctgcaagata gacacgaaac
      301 taaagatgta cgcactaaaa taaattatga ccctgtggga tggcacaact atcaatttcc
      361 atacggagat ggctcaaaat cttcatgggt aatgaatcgt gggcatctag tcggatatca
      421 attttgtgga ttaaacgatg aaccaagaaa tttagtggca atgacagcct ggctaaacac
      481 aggtgcttat tcaggagcaa atgacagcaa tcctgaaggg atgttatact atgaaaaccg
      541 tttagattct tggcttgcac ttcaccctga cttttggcta gattataaag tcactcctat
      601 atatagtggc aatgaagtag tgcctcgaca aattgaatta cagtatgttg gaattgattc
      661 atctggtgag ttgcttacta taaggctaaa tagtaataaa gaaagtattg atgaaaatgg
      721 tgttactaca gtaatcttag aaaactctgc tccaaatatc aaccttgact atttaaatgg
      781 aactgccact cctaaaaact aaaatataaa tac
//
LOCUS       DAUGUF010000099          800 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUGUF010000099 DAUGUF010000000
VERSION     DAUGUF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.099"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(520..>800)
                     /locus_tag="VIB71_001734"
     CDS             complement(520..>800)
                     /locus_tag="VIB71_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ8823435.1"
                     /translation="ILADLGYLSRELKNNLEQKGYQLWTPLRQNMTGAKQHNHWRVMA
                     MRRTIETRFSELCSLFDIEHTLTRGVTGLQLRIEQIILAYNLKYVEFN"
BASE COUNT          253 a          155 c          138 g          254 t
ORIGIN      
        1 tttaaacaca taaaattaaa agaagaggtt ttttatgaaa aaaacactat tactaagtgc
       61 cgctgcatta atggtagcta gcaccgttgc tctatcaact aattctgtaa gtgcatcttc
      121 atacttaaat aatccttact ataatactag ccgctttcta agataaaacg gcactcaagt
      181 tcttagagaa gctagatatg cttccgagct aaaaattaga aacctactag atcagtatgg
      241 aatcgttggt gaggaatata aaggctattt taactgctac tataggcaag ctcgtcaagc
      301 tctaagttta ggacaagttg atgatgtcat caatagtttg gaaaggaact tacaagaacg
      361 ccaagacaac gactaatcta tctgtaaaag aagcaattca tctcttgctt ctttttttgt
      421 tgctttagtc ctccacccct gtaatgttcc acaaactcca gccaagcttt gaaaaggcaa
      481 cagttttctg tgcaacattt ataaagtata ctcgtggtgc tagttaaact caacgtattt
      541 cagattataa gcaaggataa tttgttcgat tctcaattgt aatcctgtaa ctcctctagt
      601 cagtgtgtgt tctatatcaa aaagggaaca aagttctgaa aatcgagttt caatagttcg
      661 tctcatagcc attactctcc aatgattatg ctgtttagcc cctgtcatat tttgacgcaa
      721 gggtgtccat agctgatagc ctttttgttc cagattattt ttcagctcac ggctaaggta
      781 gcccaagtct gctaaaatga
//
LOCUS       DAUGUF010000100          773 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUGUF010000100 DAUGUF010000000
VERSION     DAUGUF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.100"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            169..609
                     /locus_tag="VIB71_001735"
     CDS             169..609
                     /locus_tag="VIB71_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEQ8823436.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGTPSKPVERLALNRVSAEQELDTIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALLSFSELYKEGMLLVEKLEKSWN"
BASE COUNT          264 a          139 c          156 g          214 t
ORIGIN      
        1 ccgtgattat ccaaggcgtc gctaatgctt taacacgaca tcgtgcgcct gtgtcaaaaa
       61 acaaaggaaa gagaggactt ttctccacaa aacaaaaaga cgtccatacg gaacgccccc
      121 ttggttaaat ttaagcttaa ataaattata ccacattggg gggctttcat gacgtttttt
      181 cctgagattg atatccaaaa aacaaaatcc aacgccaagc gtaaattgag agagtatcca
      241 cgctggcgga ggatagctaa tgatgtagat actcaaaaag ttacagctac ttactccttt
      301 gagccaagac aaccgcatgg aacgccaagc aagcctgttg agagactagc gctcaaccgt
      361 gtgtcggcag aacaggagct ggatacgatt gagagagcag tcaacgggat atttgatcca
      421 gagtatagat tgatactgat tgacaagtat ttgctcacat atccaaagac tgattgtgac
      481 atttatacaa aacttggtta tgaaaaaagc cagtattaca acatgctaga taatgctttg
      541 ttgtcgttct cagagctata taaagaggga atgttgcttg tcgaaaaatt ggaaaaaagc
      601 tggaattaat atggaataat tatgtacttt atatataatt attcatgtta ttatagtact
      661 atcaaaataa caagaagaga taacctttta atcaattggc tatttattta gtcgccaact
      721 ttaactacaa tcaaacttgt tattttgtag cctgatggcg gtacagcgag ttg
//
LOCUS       DAUGUF010000101          748 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUGUF010000101 DAUGUF010000000
VERSION     DAUGUF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.101"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(7..78)
                     /locus_tag="VIB71_001736"
     tRNA            complement(7..78)
                     /locus_tag="VIB71_001736"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43..45),aa:Glu,seq:ttc)
     gene            complement(101..174)
                     /locus_tag="VIB71_001737"
     tRNA            complement(101..174)
                     /locus_tag="VIB71_001737"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(138..140),aa:Ile,seq:gat)
     gene            complement(209..279)
                     /locus_tag="VIB71_001738"
     tRNA            complement(209..279)
                     /locus_tag="VIB71_001738"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(245..247),aa:Gly,seq:tcc)
     gene            complement(292..364)
                     /locus_tag="VIB71_001739"
     tRNA            complement(292..364)
                     /locus_tag="VIB71_001739"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(329..331),aa:Phe,seq:gaa)
     gene            complement(385..458)
                     /locus_tag="VIB71_001740"
     tRNA            complement(385..458)
                     /locus_tag="VIB71_001740"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(422..424),aa:Met,seq:cat)
     gene            complement(468..557)
                     /locus_tag="VIB71_001741"
     tRNA            complement(468..557)
                     /locus_tag="VIB71_001741"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(519..521),aa:Ser,seq:tga)
     gene            complement(580..653)
                     /locus_tag="VIB71_001742"
     tRNA            complement(580..653)
                     /locus_tag="VIB71_001742"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(617..619),aa:Ile,seq:cat)
     gene            complement(674..747)
                     /locus_tag="VIB71_001743"
     tRNA            complement(674..747)
                     /locus_tag="VIB71_001743"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(711..713),aa:Met,seq:cat)
BASE COUNT          211 a          204 c          172 g          161 t
ORIGIN      
        1 ataatatagt ccgtacggga ttcgaacccg tgttaccgcc gtgaaaaggc ggtgtcttaa
       61 ccccttgacc aacggaccat aataatataa ttatagacaa tgggcacgag tggactcgaa
      121 ccaccgacct cacgcttatc aggcgtgcgc tctaaccacc tgagctacgc gcccaagctt
      181 ttattgatat agcttgggaa aactataaag cgggtgacga gaatcgaact cgcgacaaca
      241 gcttggaagg ctgtagtttt accactaaac tacacccgca atatgataac atggcgcgag
      301 acggaatcga accgccgaca catggagctt caatccattg ctctaccaac tgagctaccg
      361 agccaacaac tacatactta tgtattgcgg gagcaggatt tgaacctacg accttcgggt
      421 tatgagcccg acgagctacc taactgctcc atcccgcgat agttaaaagg aggatgtggg
      481 attcgaaccc acgcacgctt ttacacgcct gacggttttc aagaccgttc ccttcagccg
      541 gacttgggta atcctccaaa ataatgatta tctatgatat ggaccttgta ggactcgaac
      601 ctacgaccgc tcggttatga gccgagtgct ctaaccagtt gagctaaagg tcccaagtca
      661 tccataaaaa taatagcggc gaaggggatc gaacccccga cctcccgggt atgaaccgga
      721 cgctctagcc agctgagcta caccgcca
//
LOCUS       DAUGUF010000102          748 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUGUF010000102 DAUGUF010000000
VERSION     DAUGUF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.102"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..735
                     /locus_tag="VIB71_001744"
     CDS             <1..735
                     /locus_tag="VIB71_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEQ8823437.1"
                     /translation="FFSVELNQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGIT
                     GPMLILAKLKSEKILSVEVGDILNKAINLMFLFRRDDKLWPGKIYTSNILDLDLNYLP
                     TRMAWCYGTPGTAVALFKMCQLIDLNFIDDINESLIAQMRSSDKNVYSLTMCHGLAGV
                     TFIYDLIGKNYSSERLTRFAEELRQQIITSFSTTKVFGYTDREKFGEIEVELESIGIL
                     QGVSGIVLFLLNPYSDEELLWQRIFI"
BASE COUNT          263 a           84 c          149 g          252 t
ORIGIN      
        1 tttttttctg tagagttaaa tcaaattgga aattatcttt tgaaatatat tgagacaatt
       61 ttaaataagg taactaattg ttctgaagat agagaagctg aatttgatct aggaattgca
      121 catggaatta ctggtcctat gctaatccta gcaaaattaa aatcagaaaa aattttgagt
      181 gtagaagtag gagatatact gaataaagct ataaatttaa tgtttttatt tagaagggat
      241 gacaaactat ggcctggaaa aatttatact agtaatattt tggatcttga tttaaattat
      301 cttcctacta gaatggcatg gtgttacggt acgcctggaa ctgcagttgc cctttttaaa
      361 atgtgtcaat tgatagattt aaattttatt gacgatatta atgaaagttt aattgctcag
      421 atgagaagtt cagacaaaaa tgtctattct cttacaatgt gccatggttt ggcaggagta
      481 acttttatat atgacttgat tggtaaaaat tattcaagtg agaggctaac tcgctttgca
      541 gaagagcttc gccaacaaat aattacatcg ttttcaacta caaaagtatt tgggtatact
      601 gacagagaaa aatttggaga aatagaagtt gaactggagt caatagggat attgcaaggg
      661 gtatcaggga tagtgttatt cttattaaat ccttacagtg acgaggagct attgtggcaa
      721 agaatattta tttaatttga aaaggaga
//
LOCUS       DAUGUF010000103          724 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUGUF010000103 DAUGUF010000000
VERSION     DAUGUF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.103"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(5..78)
                     /locus_tag="VIB71_001745"
     tRNA            complement(5..78)
                     /locus_tag="VIB71_001745"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42..44),aa:Arg,seq:acg)
     gene            complement(95..179)
                     /locus_tag="VIB71_001746"
     tRNA            complement(95..179)
                     /locus_tag="VIB71_001746"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(143..145),aa:Leu,seq:taa)
     gene            complement(188..259)
                     /locus_tag="VIB71_001747"
     tRNA            complement(188..259)
                     /locus_tag="VIB71_001747"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(225..227),aa:Gly,seq:gcc)
     gene            complement(272..344)
                     /locus_tag="VIB71_001748"
     tRNA            complement(272..344)
                     /locus_tag="VIB71_001748"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(309..311),aa:Thr,seq:tgt)
     gene            complement(355..436)
                     /locus_tag="VIB71_001749"
     tRNA            complement(355..436)
                     /locus_tag="VIB71_001749"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(400..402),aa:Leu,seq:tag)
     gene            complement(442..514)
                     /locus_tag="VIB71_001750"
     tRNA            complement(442..514)
                     /locus_tag="VIB71_001750"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(479..481),aa:Lys,seq:ttt)
     gene            complement(546..618)
                     /locus_tag="VIB71_001751"
     tRNA            complement(546..618)
                     /locus_tag="VIB71_001751"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(583..585),aa:Asp,seq:gtc)
     gene            complement(636..708)
                     /locus_tag="VIB71_001752"
     tRNA            complement(636..708)
                     /locus_tag="VIB71_001752"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(673..675),aa:Val,seq:tac)
BASE COUNT          186 a          209 c          159 g          170 t
ORIGIN      
        1 ctgatgcacc ctagaggagt cgaacctcta accgcctgat tcgtagtcag gtactctatc
       61 cagttgagct aagggtgcta tttcaaaaaa ttaatgccga ggaccggaat cgaaccggta
      121 cgatgtaaac catcgcagga ttttaagtcc tgtgcgtctg ccagttccgc caccccggct
      181 cctcaaaagc gaacgacggg attcgaaccc gcgaccccca ccttggcaag gtgatgttct
      241 accactgaac tacgttcgca actaatctca atgccggcta catgacttga acacgcgacc
      301 ctctgattac aaatcagatg ctctaccaac tgagctaagc cggctaatct tttatgcggg
      361 ttaagggact tgaaccccca cgccgttaag cgccagatcc taaatctggt gcgtctgcca
      421 attccgccaa acccgctttt atgacccgta ctgggctcga accagtgacc cattgattaa
      481 aagtcaattg ctctaccaac tgagctaacg agtctttcct tcaaaaaata cgactactct
      541 ttgaacggtc ccgacgggaa tcgaacccgc gatcttcgcc gtgacagggc gacgtgataa
      601 ccgctacact acgggacctg tattttccaa tactatggga gttaacggga tcgaaccgct
      661 gaccctctgc ttgtaaggca gatgctctcc cagctgagct aaactcccat tgagtgtgtc
      721 atta
//
LOCUS       DAUGUF010000104          621 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUGUF010000104 DAUGUF010000000
VERSION     DAUGUF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.104"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            complement(<1..395)
                     /locus_tag="VIB71_001753"
     CDS             complement(<1..395)
                     /locus_tag="VIB71_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ8823438.1"
                     /translation="MHNEKSNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYL
                     KDLLRRQESQKRQFHKLAYEEIGEVAHAIP"
     gene            complement(391..464)
                     /locus_tag="VIB71_001754"
     tRNA            complement(391..464)
                     /locus_tag="VIB71_001754"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(428..430),aa:Arg,seq:acg)
     gene            complement(544..617)
                     /locus_tag="VIB71_001755"
     tRNA            complement(544..617)
                     /locus_tag="VIB71_001755"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(581..583),aa:Asn,seq:gtt)
BASE COUNT          181 a          148 c           94 g          198 t
ORIGIN      
        1 ggaatggcat gtgcaacctc ccctatctct tcatatgcta acttatggaa ctgacgcttt
       61 tgactttctt gacggcgtaa taaatctttc aaataagatg aaaattttgt tttaaaatag
      121 cgatataaac gctcttcttc ctcaattaac tctgggtacc tttctagtaa ctgtaataag
      181 ataatatgtc cttcttgtaa ccagtcatct ctatcccaca attgaatata atagtgtcgc
      241 tttaatttca aaataatggg cttaactttt tcaaacgctg ctcttgtctc tatcgacatt
      301 ttgagtctcc ttttcttttt aactatccct agtataaaga gaaccacaaa aaaacaacag
      361 gacactaatg tcctgttgct tttttcatta tgcaccctag aggagtcgaa cctctaaccg
      421 cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgccaacgc atatcttgcc
      481 tctatcttac cacactcttc tctaaaatgc aaaaaaagat aggacgcttc ctacctctct
      541 ctactccgcc agtaggactc gaacctacga catcatgatt aacagtcatg cgctactacc
      601 aactgagcta tggcggataa a
//
LOCUS       DAUGUF010000105          357 bp    DNA     linear   BCT 02-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain AUSMDU00078789
            SAMN33608943-rid17956093.denovo.105, whole genome shotgun sequence.
ACCESSION   DAUGUF010000105 DAUGUF010000000
VERSION     DAUGUF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33608943
            Sequence Read Archive: SRR23751493
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001723256.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001723256.1
            Genome Coverage       :: 230x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:14:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,756
            CDSs (total)                      :: 1,713
            Genes (coding)                    :: 1,673
            CDSs (with protein)               :: 1,673
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 21 of 40
            Pseudo Genes (incomplete)         :: 18 of 40
            Pseudo Genes (internal stop)      :: 11 of 40
            Pseudo Genes (multiple problems)  :: 9 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33608943-rid17956093.denovo.105"
                     /strain="AUSMDU00078789"
                     /serotype="EMM12.0"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST36"
     gene            <1..>357
                     /locus_tag="VIB71_001756"
     CDS             <1..>357
                     /locus_tag="VIB71_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEQ8823439.1"
                     /translation="SDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQLSQENRYFIFSFK
                     PDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNLIRKMCLYFLKVMV
                     FPKKDLSYRRKQRYISV"
BASE COUNT          108 a           62 c           74 g          113 t
ORIGIN      
        1 ttccgatatc aaatggttgt gtcaaaacca tcccaaatgg cataagttac gtggtattgg
       61 gatgactcgt aacacgattg ataaggatgg tcagctgagt caagagaatc gttattttat
      121 ctttagcttt aagccggatg tcctcacatt tgccaattgt gtacgaggtc attggcagat
      181 agagagtatg cactggttat tggacgttgt ttatcatgaa gatcatcatc agacattgga
      241 taaaagagcc gcatttaacc taaatcttat ccgaaaaatg tgcttatatt ttctcaaagt
      301 gatggtattt cctaaaaaag acctcagtta tcgtcgcaaa caacggtata tttctgt
//
