LOCUS       DAUNLR010000001       105618 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUNLR010000001 DAUNLR010000000
VERSION     DAUNLR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 105618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105618
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.001"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..829
                     /locus_tag="VLL59_000001"
     CDS             <1..829
                     /locus_tag="VLL59_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="HER6508167.1"
                     /translation="AVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVE
                     EKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYD
                     DIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRG
                     IGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHH
                     QTLDKRAAFNLNLIRKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG"
     gene            1002..1271
                     /locus_tag="VLL59_000002"
     CDS             1002..1271
                     /locus_tag="VLL59_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HER6508168.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            1268..1687
                     /gene="ruvX"
                     /locus_tag="VLL59_000003"
     CDS             1268..1687
                     /gene="ruvX"
                     /locus_tag="VLL59_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HER6508169.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            1699..2004
                     /locus_tag="VLL59_000004"
     CDS             1699..2004
                     /locus_tag="VLL59_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HER6508170.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            2417..3976
                     /locus_tag="VLL59_000005"
     CDS             2417..3976
                     /locus_tag="VLL59_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HER6508171.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            4073..6271
                     /gene="nrdD"
                     /locus_tag="VLL59_000006"
     CDS             4073..6271
                     /gene="nrdD"
                     /locus_tag="VLL59_000006"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HER6508172.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            6453..6599
                     /locus_tag="VLL59_000007"
     CDS             6453..6599
                     /locus_tag="VLL59_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508173.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSTKKADKKSRVQELKARFLEKSK
                     KQDN"
     gene            6628..7563
                     /locus_tag="VLL59_000008"
     CDS             6628..7563
                     /locus_tag="VLL59_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HER6508174.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTNLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKELSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            7572..8081
                     /locus_tag="VLL59_000009"
     CDS             7572..8081
                     /locus_tag="VLL59_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HER6508175.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSYAISKNITTILVTCDETNVASRAVIVANGGILEDSRGGTERY
                     WIEEQRGDK"
     gene            8081..8695
                     /gene="nrdG"
                     /locus_tag="VLL59_000010"
     CDS             8081..8695
                     /gene="nrdG"
                     /locus_tag="VLL59_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HER6508176.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRCELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(8869..9600)
                     /gene="yaaA"
                     /locus_tag="VLL59_000011"
     CDS             complement(8869..9600)
                     /gene="yaaA"
                     /locus_tag="VLL59_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HER6508177.1"
                     /translation="MLTFLIPTAKEMTIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEESAKKEQQRWQDMASQKSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKEEA"
     gene            complement(9759..10499)
                     /locus_tag="VLL59_000012"
     CDS             complement(9759..10499)
                     /locus_tag="VLL59_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HER6508178.1"
                     /translation="MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLVLNHFLTRGISLEGAAD
                     HGYSEAIYLSDPEGNGIEIYHDKPVEQWDIRDNGQIIGVTEPMDAQSMLNQLTDIPEH
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHW
                     SGPYLKKHQEGAPGLAFLTIHIETPLLF"
     gene            10746..11018
                     /locus_tag="VLL59_000013"
     CDS             10746..11018
                     /locus_tag="VLL59_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6508179.1"
                     /translation="MLILRDLLKGTLRFGQLKSSIGSVSQKVLTAQLRAMEADGLVHR
                     EVYAEVPPRVEYSLTETGLSLAPVIEAMSDWDQTYQEKHADLFEEG"
     gene            complement(11296..12009)
                     /gene="treR"
                     /locus_tag="VLL59_000014"
     CDS             complement(11296..12009)
                     /gene="treR"
                     /locus_tag="VLL59_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HER6508180.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            12220..14244
                     /gene="treP"
                     /locus_tag="VLL59_000015"
     CDS             12220..14244
                     /gene="treP"
                     /locus_tag="VLL59_000015"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HER6508181.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEEVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSE
                     APAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDAFTVTVEGSLPRQIKANDKLAVAMKK"
     gene            14311..15939
                     /gene="treC"
                     /locus_tag="VLL59_000016"
     CDS             14311..15939
                     /gene="treC"
                     /locus_tag="VLL59_000016"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HER6508182.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTASEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAK
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYAGEVELELPPR
                     YQHGQVLISNYEKVSICEKVMLKPYQTLAILADN"
     gene            16147..18042
                     /gene="pepO"
                     /locus_tag="VLL59_000017"
     CDS             16147..18042
                     /gene="pepO"
                     /locus_tag="VLL59_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HER6508183.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGDHVPDDAILANFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(18208..19248)
                     /locus_tag="VLL59_000018"
     CDS             complement(18208..19248)
                     /locus_tag="VLL59_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HER6508184.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(19382..20149)
                     /gene="rpsB"
                     /locus_tag="VLL59_000019"
     CDS             complement(19382..20149)
                     /gene="rpsB"
                     /locus_tag="VLL59_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HER6508185.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            20453..23527
                     /locus_tag="VLL59_000020"
     CDS             20453..23527
                     /locus_tag="VLL59_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HER6508186.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDDIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLTYINSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVTY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIRQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(23558..24544)
                     /locus_tag="VLL59_000021"
     CDS             complement(23558..24544)
                     /locus_tag="VLL59_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HER6508187.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSSSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHN"
     gene            complement(24730..26271)
                     /gene="hutH"
                     /locus_tag="VLL59_000022"
     CDS             complement(24730..26271)
                     /gene="hutH"
                     /locus_tag="VLL59_000022"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HER6508188.1"
                     /translation="MTRVINLDGESLTLEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLLEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAVGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTIATQSRV
                     QDPYTLRCIPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(26282..27634)
                     /locus_tag="VLL59_000023"
     CDS             complement(26282..27634)
                     /locus_tag="VLL59_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HER6508189.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCVCTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDAPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMDQMPPKEQI
                     "
     gene            complement(27854..28450)
                     /locus_tag="VLL59_000024"
     CDS             complement(27854..28450)
                     /locus_tag="VLL59_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HER6508190.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     KSTVALRQTTFTLLDGYHRILMTLDKPITLSDLSHAKEISLTPFEPYAFEGDTRIVSR
                     GICQDINLMYDDQYQGQLLPVWSDTLFEAPKADCQLLYALRKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCLNQTSPAQNPVAVWAGLWYKT"
     gene            complement(28472..30145)
                     /locus_tag="VLL59_000025"
     CDS             complement(28472..30145)
                     /locus_tag="VLL59_000025"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HER6508191.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDEEALCLYGKYKAKIDAH
                     QLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKANLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRKLAEKVVTLAEQDNQFCFVYEEDDSIETKLT
                     KIVTKVYGGKGIRLTPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(30163..30789)
                     /locus_tag="VLL59_000026"
     CDS             complement(30163..30789)
                     /locus_tag="VLL59_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HER6508192.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQVIIEDLHTKSSRLQQDLLDAIDKDTEAFNLVSAVFDMPKETDEDKA
                     ARRTAMQEALKTAAQSPFEMMTLMVEALETTETAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(30800..31699)
                     /gene="ftcD"
                     /locus_tag="VLL59_000027"
     CDS             complement(30800..31699)
                     /gene="ftcD"
                     /locus_tag="VLL59_000027"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HER6508193.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELDIPIFLYEDSATRPERQNLAKIRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYHKQVLENHLLG"
     gene            complement(31787..33817)
                     /locus_tag="VLL59_000028"
     CDS             complement(31787..33817)
                     /locus_tag="VLL59_000028"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HER6508194.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRFRPKDRIYGKPIDEYKGTC
                     TATKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYQLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWVSQIAESPEEALQLARKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVREGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            34108..35373
                     /locus_tag="VLL59_000029"
     CDS             34108..35373
                     /locus_tag="VLL59_000029"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HER6508195.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITNDDIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQGKVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(35431..36963)
                     /gene="ahpF"
                     /locus_tag="VLL59_000030"
     CDS             complement(35431..36963)
                     /gene="ahpF"
                     /locus_tag="VLL59_000030"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HER6508196.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHDSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSTYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(36984..37544)
                     /gene="ahpC"
                     /locus_tag="VLL59_000031"
     CDS             complement(36984..37544)
                     /gene="ahpC"
                     /locus_tag="VLL59_000031"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HER6508197.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            37950..38020
                     /locus_tag="VLL59_000032"
     tRNA            37950..38020
                     /locus_tag="VLL59_000032"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37982..37984,aa:Cys,seq:gca)
     gene            38539..38742
                     /locus_tag="VLL59_000033"
     CDS             38539..38742
                     /locus_tag="VLL59_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HER6508198.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            38938..39399
                     /locus_tag="VLL59_000034"
     CDS             38938..39399
                     /locus_tag="VLL59_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HER6508199.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            39399..41843
                     /locus_tag="VLL59_000035"
     CDS             39399..41843
                     /locus_tag="VLL59_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HER6508200.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            42021..42311
                     /gene="groES"
                     /locus_tag="VLL59_000036"
     CDS             42021..42311
                     /gene="groES"
                     /locus_tag="VLL59_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HER6508201.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            42347..43978
                     /gene="groL"
                     /locus_tag="VLL59_000037"
     CDS             42347..43978
                     /gene="groL"
                     /locus_tag="VLL59_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HER6508202.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            44180..44485
                     /locus_tag="VLL59_000038"
     CDS             44180..44485
                     /locus_tag="VLL59_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6508203.1"
                     /translation="MEPMKSYSHIWVLEGNFGEIFKTFRESKGLRLKDVAKAGISTSQ
                     LSRFEKGETDLTISTFMLILDESNMLIDEFMYAVHDFHRDDLNELLSKSEAFRNNSR"
     gene            complement(45207..46706)
                     /locus_tag="VLL59_000039"
     CDS             complement(45207..46706)
                     /locus_tag="VLL59_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HER6508204.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVKEKPKNKKGLNRS"
     gene            46953..48593
                     /locus_tag="VLL59_000040"
     CDS             46953..48593
                     /locus_tag="VLL59_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508205.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNHKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDKSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(48682..49683)
                     /locus_tag="VLL59_000041"
     CDS             complement(48682..49683)
                     /locus_tag="VLL59_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HER6508206.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHSVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            50259..50639
                     /locus_tag="VLL59_000042"
     CDS             50259..50639
                     /locus_tag="VLL59_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HER6508207.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            50678..53014
                     /locus_tag="VLL59_000043"
     CDS             50678..53014
                     /locus_tag="VLL59_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HER6508208.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKARLTPQHNQKQYSPNAHH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            53063..53215
                     /gene="rpmG"
                     /locus_tag="VLL59_000044"
     CDS             53063..53215
                     /gene="rpmG"
                     /locus_tag="VLL59_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HER6508209.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            53229..53405
                     /gene="secE"
                     /locus_tag="VLL59_000045"
     CDS             53229..53405
                     /gene="secE"
                     /locus_tag="VLL59_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HER6508210.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(53642..54415)
                     /locus_tag="VLL59_000046"
     CDS             complement(53642..54415)
                     /locus_tag="VLL59_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HER6508211.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEIKAYHPEDLADYQAVFLNHNIHCYF"
     gene            54541..55287
                     /locus_tag="VLL59_000047"
     CDS             54541..55287
                     /locus_tag="VLL59_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019317626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HER6508212.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQNKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            55303..56283
                     /locus_tag="VLL59_000048"
     CDS             55303..56283
                     /locus_tag="VLL59_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HER6508213.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRKQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            56571..56891
                     /locus_tag="VLL59_000049"
     CDS             56571..56891
                     /locus_tag="VLL59_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HER6508214.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            56919..57227
                     /locus_tag="VLL59_000050"
     CDS             56919..57227
                     /locus_tag="VLL59_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HER6508215.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            57237..58541
                     /locus_tag="VLL59_000051"
     CDS             57237..58541
                     /locus_tag="VLL59_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HER6508216.1"
                     /translation="MAKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILILSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            58751..61168
                     /locus_tag="VLL59_000052"
     CDS             58751..61168
                     /locus_tag="VLL59_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HER6508217.1"
                     /translation="MTETKSPYFGHLTDRMAHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWQALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            61183..61851
                     /locus_tag="VLL59_000053"
     CDS             61183..61851
                     /locus_tag="VLL59_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HER6508218.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQGYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     DSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            61908..62996
                     /locus_tag="VLL59_000054"
     CDS             61908..62996
                     /locus_tag="VLL59_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HER6508219.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(63078..63587)
                     /locus_tag="VLL59_000055"
     CDS             complement(63078..63587)
                     /locus_tag="VLL59_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HER6508220.1"
                     /translation="MSTDHHLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLFEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGNSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            63951..64766
                     /gene="sdaB"
                     /locus_tag="VLL59_000056"
     CDS             63951..64766
                     /gene="sdaB"
                     /locus_tag="VLL59_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HER6508221.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(65007..65849)
                     /gene="ropB"
                     /locus_tag="VLL59_000057"
                     /gene_synonym="rgg1"
     CDS             complement(65007..65849)
                     /gene="ropB"
                     /locus_tag="VLL59_000057"
                     /gene_synonym="rgg1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="RopB (Regulator of Protease B) is a paralog of the
                     quorum-sensing transcriptional regulators Rgg2 and Rgg3,
                     which bind short, hydrophobic peptides encoded by genes in
                     their respective vicinities. RopB binds the leaderless
                     short peptide SIP (SpeB-inducing peptide), with sequence
                     MWLLLLFL; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     RopB/Rgg1"
                     /protein_id="HER6508222.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEKDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            66348..66518
                     /locus_tag="VLL59_000058"
     CDS             66348..66518
                     /locus_tag="VLL59_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508223.1"
                     /translation="MDNPKKDKGLSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            66790..67986
                     /gene="speB"
                     /locus_tag="VLL59_000059"
     CDS             66790..67986
                     /gene="speB"
                     /locus_tag="VLL59_000059"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HER6508224.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDVNGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            67988..68293
                     /locus_tag="VLL59_000060"
     CDS             67988..68293
                     /locus_tag="VLL59_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HER6508225.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKIPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQTQINSLD"
     gene            68771..69700
                     /gene="prsA"
                     /locus_tag="VLL59_000061"
     CDS             68771..69700
                     /gene="prsA"
                     /locus_tag="VLL59_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HER6508226.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     EAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(69971..70207)
                     /locus_tag="VLL59_000062"
     CDS             complement(69971..70207)
                     /locus_tag="VLL59_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508227.1"
                     /translation="MTHRFFLTPLSTLCRRLRPKRYSKKVLADEPTGYQPPTAHGPCD
                     DTHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            70631..73705
                     /locus_tag="VLL59_000063"
     CDS             70631..73705
                     /locus_tag="VLL59_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HER6508228.1"
                     /translation="MTNCKYKLRKLSVGLVSVGTMLIAPTVLGQEVNTGATSTESSTT
                     STDTATTSGTATTTTGTSGTAASGASSEATVATAPTTNGGSQSTPAAAETTLQPQAQT
                     AVAATSAPSTSSSNAKTEEQTPKAASTTSPSTPAIATSDGNQLTGTEAETPMMEVEQY
                     TVDNKETELNVKDGTVLSQKNGGRSVSQNTKLIRNRDGEQRGIFDIKREVKTNADGTV
                     DVTVTVTPKEIDKGADVMALLDVSQKMTDADFKNAKDKIKKLVTTLTSKSNSDEHKHN
                     SRNSVRLMTFYRKVNDPIELNADNVDTKLDEVWEKAKKDWDWGVDLQGAIHKAREIFN
                     KEKEKNSGKRQHIVLFSQGESTFSYDINDKDKNDTVKKNRIAGKVTTSNPLFPWLPIF
                     NHTNQKAEVIDDVDKLLDLAEKMGISLPNGLRAGVKAIGASSSLLSTFTGSGLTEYLA
                     LNEYRSDILKEKQFDYTKRVGEGYHYHSYSKRTHGDKMPFENEIRQVLERFLPKIENK
                     EWAKKFIEIFGLQEQKVNQIGVDVIMKVINSIFYSRQYYYYNHNLSAIAEAKMAQEEG
                     ITFYSVDVTDLKPKRAKRQTVVRQKTTKKESEEDRNNKFDGYLKKMSEGDTFLDNVEK
                     KDKFKDILDELKFTDKFTNEVTVEEKSLDKVSTDASSQENGSQKVEHKKASNGSLFMS
                     PSQESLTWTISKEQLKEAFEKNSSLTFKYKLRVNKDKLLNKDKKRIKHSAPTENENSV
                     TKKIISNITTYKINGQEVKGNNLSDVSLTYSKFKVPVPQIDGHVIEPQAPKLPELPPV
                     IEHGPVLDYKEESIYRLPLEHGSNAPDTQVTIEEDTVPQRPDILVGGQSGPVDITEDT
                     QPGMSGSNDATVVEEDTAPKRPDVLVGGQSDPIDITEDTQPSVSGSNDATVVEEDTAP
                     KRPDILVGGQSDPIDITEDTQPGMSGSNDATVIEEDTKPKRFFHFDNEPQAPEKPKEQ
                     PSLSLPQAPVYKAAHHLPASGDKREASFTIVALTIIGAAGLLSKKRRDTEEN"
     gene            73886..75835
                     /locus_tag="VLL59_000064"
     CDS             73886..75835
                     /locus_tag="VLL59_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HER6508229.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAIANNSKYQAQYERVKKE
                     LDALKATSPKLGERSLYFRLVNRFLGWFGVVWDPLAIKETDHLLDLIGQVNYLVSNTE
                     FQAPEYQEAKNKLDLAVAGYDLYLSREKGRGDAPDYQVTQLTLDQLKTIKTKIQEALK
                     TFAQEVKTIQQKNPDLFPHAYVLNAKSKDITDKAQPFLVNGYYDVFYKQFLFTNTKDG
                     YNYNKEADNLASYQKLIKELLTLKAEIDQLTTDKPKNDRLETLMWESKFTLSDFRRTS
                     RLSAYYTQEDYVKKVVLSEEAPNLRTAKEKVKTLKGILYDYYVDIKDPEKAKKYRVED
                     ETLPSQPEVPAKPEAPVPGQKPAEDEGSSQATEPTNPSKENSSTDASQGSHDSENPAT
                     DSPSQPQAPDQGNHQSQVPNDKPQTDKTDTPNVPAPPQDTPNAPAIPQDTPKVPEAGG
                     QSGPAGNAEEKAPDSGPKESGQSSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTI
                     TDAPPTVSGHNASTQPQSVVEDTAPQRPDVLVGGQSEPIDITQDTQPGMSGSNDATVI
                     NEDTKPKRVFHFDNKEPQASEKAAEQKLAPHDSHTTPQTSDDTAAPHLPASGDKPEKV
                     FALAALTMVAAAGLLSKKRRNTDKN"
     gene            75968..76264
                     /locus_tag="VLL59_000065"
     CDS             75968..76264
                     /locus_tag="VLL59_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HER6508230.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDISCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            76411..76695
                     /locus_tag="VLL59_000066"
     CDS             76411..76695
                     /locus_tag="VLL59_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HER6508231.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            77119..78387
                     /locus_tag="VLL59_000067"
     CDS             77119..78387
                     /locus_tag="VLL59_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HER6508232.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGTYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            78374..79048
                     /locus_tag="VLL59_000068"
     CDS             78374..79048
                     /locus_tag="VLL59_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508233.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            79061..80278
                     /locus_tag="VLL59_000069"
     CDS             79061..80278
                     /locus_tag="VLL59_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508234.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVVSGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            80372..81025
                     /locus_tag="VLL59_000070"
     CDS             80372..81025
                     /locus_tag="VLL59_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6508235.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQASLDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWKGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            81022..82410
                     /locus_tag="VLL59_000071"
     CDS             81022..82410
                     /locus_tag="VLL59_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HER6508236.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLASRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            82512..84137
                     /locus_tag="VLL59_000072"
     CDS             82512..84137
                     /locus_tag="VLL59_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HER6508237.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTAD
                     TDTDDESETPKKDKKSKETASQHDTQKDHKSSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNNTNQPDSSDQSTPSPKDQSSQKESQNKDGRSTPSPDQQKDQTPDKTPEKSADKT
                     PEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFAPWRESDKDLSKLKPSSRSSAAYVR
                     HWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRA
                     IVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANK
                     NQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPE
                     IPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSESYSFGQCTWYAYNRVKELGYQVDR
                     YMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISE
                     SNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP"
     gene            84215..84466
                     /locus_tag="VLL59_000073"
     CDS             84215..84466
                     /locus_tag="VLL59_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508238.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            85141..86742
                     /locus_tag="VLL59_000074"
     CDS             85141..86742
                     /locus_tag="VLL59_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HER6508239.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGCAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIE
                     KQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSP
                     SKSHSDKEVQKPEKPDNSVKQATSS"
     gene            86930..88177
                     /gene="mrp"
                     /locus_tag="VLL59_000075"
     CDS             86930..88177
                     /gene="mrp"
                     /locus_tag="VLL59_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Mrp"
                     /protein_id="HER6508240.1"
                     /translation="MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKADLS
                     TQEHPRVTKAREEALEEVLRSWDYGSVKAALAGSYRKNLQLENTIKQKDKELSFLSKV
                     LDEAAKKYRESSDKYKQEIGQLKAAAEAEAQKALDALNNKNKQISDLTNENAQLKEAI
                     EGYVQTIQNASREIAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEEIAKLQSEAAT
                     LENLLGSAKHELTDLQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKLDAAN
                     AEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEE
                     LAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEETTNPF
                     FTAAALTVIASAGVLALKRKEES"
     gene            88402..89424
                     /locus_tag="VLL59_000076"
     CDS             88402..89424
                     /locus_tag="VLL59_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407885.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HER6508241.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTEVKAAES
                     RSVSQGSVSLELYDKLSDENDILREKQDEYLTKIDGLDKENKEYASQLAKNQKEREEL
                     ELEYLRKSDKEYKEHQQYRQEQEERQKNQEQLERKYQREVEKRYQEQLQKQQQLETEK
                     QISEASRKSLSRDLEASRAAKKELEAEHQKLKEEKQISDASRQGLSRDLEASREAKKK
                     VEADLAEANSKLQALEKLNKELEEGKKLSEKEKAELQAKLEAEAKALKEQLAKQAEEL
                     AKLKGNQTPNAKVAPQANRSRSAMTQQKRTLPSTGETANPFFTAAAATVMVSAGMLAL
                     KRKEEN"
     gene            89634..90614
                     /locus_tag="VLL59_000077"
     CDS             89634..90614
                     /locus_tag="VLL59_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HER6508242.1"
                     /translation="MARQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRAEGV
                     KATKNLSEEAKYAALRDENTGLRGDQTKLVKKLEEEQEKSKNLEKQKQELENQALNFQ
                     DVIETQEKEKEDLKTTLAKTTKENEISEASRKGLSRDLEASRAAKKELEAKHQKLEAD
                     HQALEAKHQKLAEEHQVSETSRKGLSRDLEASREANKKVTSELTQAKAQLSALEESKK
                     LSEKEKAELQAKLDAQGKALKEQLAKQTEELAKLRAEKAAGSKTPATKPANKERLGRA
                     AQTATRPSQNKGMRSQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            90949..94497
                     /gene="scpA/B"
                     /locus_tag="VLL59_000078"
     CDS             90949..94497
                     /gene="scpA/B"
                     /locus_tag="VLL59_000078"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HER6508243.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VEIPQPTAVSEEAPSSSKETKTPQTPSDAEETVADDANDLARQAPAKIADTPATSKAT
                     IRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA
                     KKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEG
                     AMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDET
                     KKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSP
                     DKQLTETATVKTDDQQAKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALI
                     ERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDN
                     PQKNITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAK
                     LSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYF
                     SPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELY
                     YQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKNLLAQMK
                     NGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSD
                     AKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGT
                     FAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGN
                     VVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPIS
                     SGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPIYRERIAYTYMDE
                     DLPTTEYISPNEDGTFTLPEEAETMEGGTVPLKMSDFTYVVEDMAGNITYTPVTKLLE
                     GHSNKPEQDGSDQAPDKKPETKPEQDGSDQVPDKKPETKPEQDGSGQAPDKKPEAKPE
                     QDGSGQTPNKKPETKPEKDSSGQTPGKTPQKGQPSRALEKRSSKRALATKASTRDQLP
                     TTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED"
     gene            94594..95742
                     /gene="fbpA"
                     /locus_tag="VLL59_000079"
     CDS             94594..95742
                     /gene="fbpA"
                     /locus_tag="VLL59_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibronectin-binding protein FbpA"
                     /protein_id="HER6508244.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSMQPI
                     SSTQGNRANTSKKWYDINEYGLIPVDISFEAAKKDFKEEVEKSLLSEEQQKTYNQKIE
                     AAKNKDDLLLTYHSEYSKDIKKHSTSTEPVEASVQETQASVSDSMVTDDSTSVTADSP
                     EKTPSPETPAPSIPEVPAAPASSPESEESSVASSEETSSPETPVAPEAPALSEAPAQP
                     AESEESSVAASSEETPSPETPAAPETPEEPAAPAQPAESEESSVAATTSPSPSTPAES
                     ETQTPPAVTKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSL
                     SRQVRAHESGKYLPSTGEKAQPLFIATMTLMSLFGSLLVTKRQKETKK"
     gene            95994..96914
                     /gene="lmb"
                     /locus_tag="VLL59_000080"
     CDS             95994..96914
                     /gene="lmb"
                     /locus_tag="VLL59_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HER6508245.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            96927..99404
                     /locus_tag="VLL59_000081"
     CDS             96927..99404
                     /locus_tag="VLL59_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HER6508246.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDD
                     SKCKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTP
                     NPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEED
                     GLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDH
                     SKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHF
                     HYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGK
                     VGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSS
                     LPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPG
                     HEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKE
                     TFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQKLLAKKNAGDATDTDKPKEKQQ
                     ADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIF
                     QPEGVQFYNKNGELVTYDIKTLQQINP"
     gene            99573..99773
                     /locus_tag="VLL59_000082"
     CDS             99573..99773
                     /locus_tag="VLL59_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HER6508247.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(99855..100481)
                     /locus_tag="VLL59_000083"
     CDS             complement(99855..100481)
                     /locus_tag="VLL59_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508248.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKNLLEIVKDRNLGLIIISHDFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(100465..101268)
                     /locus_tag="VLL59_000084"
     CDS             complement(100465..101268)
                     /locus_tag="VLL59_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508249.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALKMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(101280..102101)
                     /locus_tag="VLL59_000085"
     CDS             complement(101280..102101)
                     /locus_tag="VLL59_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508250.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(102098..103075)
                     /locus_tag="VLL59_000086"
     CDS             complement(102098..103075)
                     /locus_tag="VLL59_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508251.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLISDILNSIINPQLRRKV"
     gene            complement(103188..104816)
                     /locus_tag="VLL59_000087"
     CDS             complement(103188..104816)
                     /locus_tag="VLL59_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HER6508252.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIIGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGIHSHGHDWSLLTNIAEWTWDESTK"
     gene            104995..105117
                     /locus_tag="VLL59_000088"
                     /pseudo
     CDS             104995..105117
                     /locus_tag="VLL59_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987967.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
BASE COUNT        33773 a        20391 c        21986 g        29468 t
ORIGIN      
        1 tgccgttcat caactgattt cagtggacgg taaaacgatt cgaggcaatc gaggtaaaaa
       61 tcagaagcct gttcatattg taacggctta tgatgggggt catcatctta gtttgggaca
      121 ggtagcggtt gaggagaaaa gtaatgaaat tgttgccatt cctcagttat tgcggacaat
      181 tgatatccgt aaaagcattg taacgataga cgcaatgggc acgcagacgg ctatcgttga
      241 tacgattata aaaggtaaag cagactattg cttagccgtc aaaggaaatc aagaaacact
      301 ttatgatgat attgctcttt attttagtga tgtcaactta ttggaagaac tccaagaaaa
      361 tgcacagtat tatcagactg ttgaaaaatc taggggacag attgaagtta gagaatactg
      421 ggtgtcttcc gatatcaaat ggttgtgtca aaaccatccc aaatggcata agttacgtgg
      481 tattgggatg actcgtaaca cgattgataa ggatggtcag ctgagtcaag agaatcgtta
      541 ttttatcttt agctttaagc cggatgtcct cacatttgcc aattgtgtac gaggtcattg
      601 gcagatagag agtatgcact ggttattgga cgttgtttat catgaggatc atcatcagac
      661 attggataaa agagccgcat ttaacctaaa tcttatccga aaaatgtgct tatattttct
      721 caaagtgatg gtatttccta aaaaagacct cagttatcgt cgcaaacaac ggtatatttc
      781 tgtccatttg gaagattatt tagtccaatt atttggagaa agaggctaag cagatcattg
      841 atttaaaaag gagtcttttc aaaattgatg tccgggcaca aaaggatgaa gagaaagttt
      901 tcatgcgtac ggcgtgcctt cttcgcttga aattcttgtt tatttaatag aaataagcta
      961 taataaagca tagcacttaa ttttagaaag aaggtgtaag tatgggattt acagatgaaa
     1021 cagtccgctt taagttggat gatggcgaca aacgacaaat tagtgaaaca ttaacagcag
     1081 tctatcattc acttgatgaa aagggttata atccaattaa tcaaattgtt ggttatgtct
     1141 tgagtgggga cccagcttat gttcctcgtt ataatgatgc tcgaaatcag attcgtaaat
     1201 atgaacgtga tgaaattgta gaagaacttg ttcgctacta tttacaagga aatggaattg
     1261 atgttaaatg agaataatgg gacttgatgt tggctcgaaa acggttggtg tagctattag
     1321 tgatcctctt ggctttacag cccaaggact tgaaattatc aagattgatg aggaaaaagc
     1381 agaatttggc tttacacgtt tagaagagct tgttaagcag taccaagttg aacagtttgt
     1441 tattggattg ccaaaaaata tgaataacac caatggtcca cgtgttgatg caagtataac
     1501 ttatggaaac cacatagagc acctctttgg acttccagtc cattatcaag atgaacgatt
     1561 gacgactgtt gaggcagagc gtatgcttat tgagcaagct gacattagtc gtggtaagcg
     1621 aaaaaaagtc attgataaat tagctgcaca actcatttta cagaactatt taaatcggaa
     1681 tttttaagga gataaaaaat gacacataat catgaaaatg accaccaaca cgaagttatc
     1741 acacttgtgg atgaacaagg aaatgaaacc ttgtttgaaa ttttattaac aattgatggt
     1801 cgtgaagagt ttggtaaaaa ttatgttctc ttggttccag cgggatctga agaagatgag
     1861 tctggtgaaa ttgaaatcca agcctattca tttactgaaa atgaagatgg tactgaaggg
     1921 gatttacaac cgattcctga ggattcagat gctgaatggg atatgattga agaggtattt
     1981 aatagttttc tagatgagaa ctaaattgtt agtgacacta tgttaaaaag tagccgtgag
     2041 ggctattttt ttaatgttat tttcgaataa ataagcagga ggtgataatg ataaaagaat
     2101 taaatgataa atttattaat aattataaag ctagaccttt gcatagattt agagaattat
     2161 tacagtatgt gaaaatatat cagaaattga ctaaataaaa gattctgtta tacttgtttt
     2221 ataatattct ttgacgataa tatcattttt caacttactt tgtttatgca ctgttacttt
     2281 gctatgtgca atacaaagtc atgttattta tctcatacta aaaaataatg gataatagct
     2341 atgttagact agtgatatga agaaatatta cttttattga atcgttagag aatatgatat
     2401 ttcaaggaga aaaatagtga tcgagttaaa cgatgaattc atccgaaaag agacgataga
     2461 actggccaac gatggcccac gagtacacac cactcaatat gaaactaaag tacctcggct
     2521 tcataaatgc tatctgcttt tctttagcat tattatcagt tctttaacaa ttgcagtacc
     2581 ttttttaaca gatgcagcca atggtcttca gtcccaaaac ttatatatag gaatgatgtt
     2641 aacgaagggg caacttccct atagtgatgc ttttacaaca ggagggctct tttactttgt
     2701 tatcattgca ttaagttatt atttgggatc gacactttgg ctagtctttg ttcaggtgtt
     2761 ttgtttttac ttatctggtt tatatcttta taaactcatt aattatatga caggctttca
     2821 aaaagtggct ttaacttttt caattagcta ctatttgttg tctgttagtc ttggttttgg
     2881 gggattgtat cctactcaac tggctatgcc atttatatta atatcggctt ggtttttaac
     2941 taagtatttt gcctgtttag tgaaagatga ggcatttatt ctttttggct ttgtaggtgc
     3001 tcttgcaatg ctaattgacc caagtaccct tatcttttgg tcttttgctt gtgtgacagt
     3061 tttttcttat aatataagcc aaaagcatct tgcaagaggt ttttatcaac tgctagcttc
     3121 gatttttggg atgattttag ttttttacac agcaggatat ttcattttga acttacaagt
     3181 gctaaatcct tatttatcac aaacgatgat ttatcctttt acttttttta aatcaggaaa
     3241 cttatcgttg ctttttggac tggctattca gttgttcttc gctttggggc ttggtctttt
     3301 gacgggaatg gagaatgtca ttaggcgatt taaaaacaat tctgataggg tcgtcaagtg
     3361 gctatttgtc atggtcattc tagaatctat acttgtggct atattttcac aagactatcg
     3421 cccctatcat cttttacctc ttttaccttt tggattaatt ttgactgcta ttcctgttgg
     3481 ctatcagtat ggtataggat taggtcagag tagtcatcgc agacgtcatg gtaaaaatgg
     3541 tgttggtcga gtaatgatga tttatcttaa gagacacttt tatttgccaa ttttaattgt
     3601 agggacaata ctaatctgtt ctacttattg tttcattagt agtattcctc ttaatcagga
     3661 gcgtgatcat attgctagtt atttagaaca gaaactaaat aaaactcaat ctatttatgt
     3721 ttgggatgat acttctaaaa tttatttgga cagtaaagct aaatctgttt ctcaatttag
     3781 ttctcctgac atcaatacgc aaaaagcgag tcatcgaaaa atattagaag atgaactatt
     3841 agaaaataag gctgcttata tcgttgttaa ccgctataaa aacctgccta aaatcattca
     3901 aaaagtatta tctactaatt acaaagtaga taaacagata acgacaaaaa gttttattgt
     3961 ttatcagaaa aagtaatcta atatcaatat attgtgttcg agcaaaaaac ttgacacaat
     4021 atattgattt ttttagttgt cgtgatataa tagttccgta aggagatttg atatggtaag
     4081 tttagaagaa gacaaggtga ctgttcaacc tgatattaaa gtgattaaac gagatggtcg
     4141 ccttgttaat tttgatagta caaaaatcta tagtgcttta ttaaaagcaa gcatgaaagt
     4201 aactcggatg tcgccacttg ttgaggctaa attagaggct atttctgatc gcattatagc
     4261 agaaattatt gagcgttttc caactaatat caaaatttat gaaatccaaa atattgtaga
     4321 gcataagctt cttgcagcta atgaatatgc tattgcaaaa gaatacatta attatcgtac
     4381 tcagcgtgac tttgcacgtt cacaagcaac agatatcaat ttttctattg ataaattaat
     4441 taataaagat caaacagttg ttaatgaaaa tgctaacaaa gatagcgatg tttttaatac
     4501 tcaacgagat ttaactgctg gaatcgtagg gaaatcaatt ggtttaaaaa tgttaccttc
     4561 gcatgttgct aatgctcatc aaaaaggaga tatccattac catgatttgg attacagtcc
     4621 ttatacaccg atgacgaact gctgtttaat tgactttaag ggcatgttag ccaatggctt
     4681 taaaattggt aatgctgaag tggaaagtcc caagtctatt caaactgcaa cagctcagat
     4741 ctcacagatt attgcgaatg tagcatcaag tcagtacggc ggatgcacag ctgatcgcat
     4801 tgacgagttt ttagccccat atgcggagct taactttaaa aaacatatgg ctgatgctaa
     4861 gaaatggatc gttgagacta agagagaaag ctatgctttt gaaaagactc aaaaagatat
     4921 ttatgatgcg atgcagtctt tggagtatga aattaatacg ctctttacgt ctaatggtca
     4981 aacaccattt acttctttag gatttggttt ggggacgtct tggtttgaac gtgagattca
     5041 aaaagctatt ttgaccattc ggattaatgg tcttggtagt gaacatcgca cggctatttt
     5101 ccctaaatta attttcacgg ttaaacgtgg cttgaattta gaaccagatt caccaaacta
     5161 tgatattaag actttggctt tagaatgtgc gactaagcgg atgtacccgg atatgttatc
     5221 ttatgataaa attattgatt tgacaggatc tttcaaatct ccaatgggat gccgctcttt
     5281 ccttcaaggc tggaaagatg aaaatgggca agatgtgacc tcaggccgta tgaatcttgg
     5341 ggttgtcacc ctcaatttac ctcgcattgc catggaatca aatggcgata tggataagtt
     5401 ttgggagctg tttaatgaga ggatgctaat tagtaaggat gctttaattt atcgtgtcga
     5461 acgtgtcaca gaagcaaaac cagcaaatgc ccctattctt tatcaatatg gtgcttttgg
     5521 aaagcgtttg gagaagacag ggaatgtaaa tgatctcttt aagaatcgtc gtgcaacagt
     5581 ctctcttggc tatattggtc tttatgaagt ggcgtctgtt ttttatggtg gtcaatggga
     5641 aggtaatcca gatgctaaag cttttacctt gtcaattgtc aaggcaatga aacaggcctg
     5701 tgaggattgg tcagatgaat atggttatca tttctctgtt tattcgactc catcagaaag
     5761 tttgacagat cgcttttgtc gtttagatac ggaaaaattt ggcattgtga cagatattac
     5821 ggataaagaa tactatacaa attcttttca ctatgatgtg cgtaagagtc cgacaccttt
     5881 tgaaaaatta gattttgaaa aagattatcc agaagcaggt gcttcaggtg gttttatcca
     5941 ctactgtgag tatcctgttt tgcaacaaaa tccaaaggcc ttggaagcgg tttgggacta
     6001 tgcttatgat cgtgtggggt atttgggaac caatacgcct attgataaat gctataattg
     6061 ccaatttgaa ggtgatttta ccccaacaga acgtggtttt acttgcccaa actgtggcaa
     6121 taatgaccct aaaacagttg atgtggtcaa acgtacatgt ggttacttgg ggaatcctca
     6181 ggcccgccca atggttaacg gtcgccataa ggaaatctct gcgcgtgtaa aacatatgaa
     6241 tggttctact ataaaatacc caggcctgta aactcaagct gggggagagc ccttttgatg
     6301 gaaatatgat atgcttaaaa ggttgcttca tgcaagcaat cttttattgt ttaatggttt
     6361 cttagcaatt gtgagataag aataactaat ccaaaacgac taattagctg ttagcaatcg
     6421 gactataaga agaaagagat aaggaagaaa taatgggaaa atatcaatta gactataaag
     6481 gaatgcagca ggtggaacgt ttccatgaga agcactctac aaaaaaggca gataaaaaat
     6541 cccgagttca agaactcaag gctcggtttt tagagaagtc aaaaaaacag gataactaaa
     6601 gtatccaata aagaaagaag gttgagtatg cttaatattg ggattgtggg actaggtgct
     6661 atttcacaaa aagcctattt accatatatg agacagctga gtgacattac ttggcatcta
     6721 tcaacgcgga atgcagcagt acgtcagcag gtcggtcagt tatttggtca cgctattctt
     6781 tacagtgatg tcaaggagtt gtcaaaaaca aacttagatg gggtctttat tcatgcggcc
     6841 acgtcggccc acgcagagtt ggctagttta tttttaaatc aggggatccc agtctttatg
     6901 gataaaccta tagctgacaa ttacctgatg acaaagaacc tctatgactt agccaaagaa
     6961 aatcagactt ttctgatggc aggatttaac aggcgtttta cacctcgtgt caaggaattg
     7021 tcaagtttgt caactaagcg taaagtggct gttgaaaaaa atgacttgaa ccggccagga
     7081 gacatgactt ttaagctctt tgatttcttt atccatcctt tagatacagc cttattcttg
     7141 acagaaggga ccttgctaaa agggcatttt caataccatc tggaagcagg cttactgagt
     7201 caagttatgg taaccttgat gaccgaaagc atgacgacta cagcttctat gaatttacaa
     7261 tcagggagtc gccgtgaggt aatggaagtt caacgggctg aagaaactta tcatttagag
     7321 aacttagacg agttatctat ttataaaggt actgaaaaaa gggtgcttgg ctttgcttct
     7381 tgggacacca ccctgcacaa aagaggtttt gaaacaatga tcgatgcctt tttagaagct
     7441 attagcacag gcgtcaatcc tgtcagccct gagtctagtc ttttaagcca ctggatttgt
     7501 caacagattg ctgactctca gctttcttat ggagagttaa cggtagagtt gcctaaggat
     7561 taggaattga tatggaaata agacgaccga ctttaaaaga taaagacgct gtattgtcaa
     7621 tgattaacga atttttagag cagaaaagtg ctacagatgg gttatggcat tttaacgtca
     7681 atgactttaa ctatgaaaca tggttggaag attccttgcg acaggaaatg ggtttgtcca
     7741 gtcaaggagt gcctgctatt caatacgtcg catttgatga gagaagtcag gctatcgggt
     7801 tcttaaatct tcgtttacgg ttaaatgaga gattacttga aaaaggtggg catattggtt
     7861 actctgtccg tcccagccag cgtgggaaag gttatgccaa ggagatgctt aaacaagctg
     7921 tcagctatgc gatttccaag aatatcacga caattttggt aacttgtgat gagactaatg
     7981 ttgcaagccg agcagttatt gtggctaacg gcggtatctt ggaagatagt cgaggtggaa
     8041 cggaacgtta ttggattgaa gaacaaagag gcgataagtg atggcagaaa agtgttggaa
     8101 taatcctaag ccaaaggaat ggcaggcaga ggagttaagt caaggccgga ttattgacta
     8161 taaggctttt aactttgttg atggtgaagg ggttcgtaat tccctttatg tgtctggttg
     8221 tttattccat tgcaaggggt gttataatgc tgcgacttgg tcttttaagg cgggaatgcc
     8281 ttatacgcaa gaacttgaag agcagataat gacggatttg gcacagcctt atgttcaggg
     8341 actgacactt ttaggtggag aacccttttt gaatacgggt atcttaattc ctctgattaa
     8401 gcgtattcgg tgtgaattgc cagaaaaaga tatttggtct tggacgggtt atacttggga
     8461 agaaatgatg cttgaaacac cagacaaact ggaaatgctg tccttaattg atattctggt
     8521 agatggtcgt tttgatatca caaaaaagaa cctcatgttg caatttagag gctcttctaa
     8581 ccagcgaatt atcgatgttc aaaagtcttt ggctgctaaa gaagtgatta tctgggataa
     8641 gttaaacgat ggggaccaaa cctttgaaca aattagtcgg gaggatttgc tttaagaagc
     8701 tgacttatcc acatgatttt tttgaaaagg tcatgtgaaa acaggtcctt taagggtgaa
     8761 ttggggagaa agtaattgtt atttcctggt tttccccaca ttatcctcat agttatccac
     8821 aggttgtgta taagttgtag aattgtgaat aaagactaaa aaagaggcct aggcctcttc
     8881 tttgatatag acaaattcat gatctgttga taggtctgga tggtagtaaa aaccagcaaa
     8941 gacaaggctt ttaaggctgt caacagtttg gcaattattt tccatacagg cagtgagaaa
     9001 tgcacctcgt gccttttttg aaatggtgga atgggttttg aattggccct ctttttctgc
     9061 cataaacttg ggacttatcc acaattgttt acagtctttg gaaaagacat cgtcaaattc
     9121 actggataaa agggaaatca cttggggatg ctctttggca aactgattat aacagggccg
     9181 ccagtaagac ttgaggcttt gtccttcaat ttttattctg gtgtgaaaat catggcggtg
     9241 ctctgcgata ggatgattag cgggaatgat accgtaaaag gatgaggtga tgtaaacttg
     9301 ctgggtgagg taagcctgtt cttgggtagt gagcttatcg cgcttgatat ggcggtacat
     9361 aaggccattg aacagttggt aggcagggta agcgaggctt ttttgagagg ccatgtcttg
     9421 ccagcgttgc tgttcttttt tagctgactc ttctttgata cgatatgatt tggccaagtc
     9481 ctccgtggtc atagctgcca tgatttttaa aatggcttgg ctgtcttgtg gaaggaggtg
     9541 tgggtgagat tccttaggga tcgtcatttc ttttgcggtt ggaattaaaa aggttagcat
     9601 agtgttattg tagtaaagtt acttgctttc tgtcaagaaa actagtcttg tccaaggatg
     9661 acgttcacac ggataccttc ctcgtcttct gtcgtgaaag aagaagaatc ttcttgtaaa
     9721 atagctaggc cgtgtaatct tgcttttttg agagtggctt aaaaaagcag gggcgtctca
     9781 atgtgaatgg tcaagaaggc taagcctgga gcaccttctt ggtgtttttt gaggtaaggt
     9841 ccagaccagt gattgaatgc aaggtgatga tggtagttcc ctgaagcaat ccagctagca
     9901 cttggaatgg tcattttatc gcctaaatca aaaacctttt gatagagaag tgaagaagcc
     9961 agagcatttt tgacactcag atggacatga ccaatgcgtg tgtcttgagc tagtaaaaag
    10021 tgttccggaa tatctgttag ttgattcaac atactttgag catccattgg ctcagtcaca
    10081 ccaataattt gcccattgtc gcggatatcc cactgctcaa cgggtttgtc atgatagatt
    10141 tcaatcccat taccctcagg atcgctgagg tagatagctt cgctatagcc gtgatcagct
    10201 gctccttcta aagagatacc tctggttaag aaatgattga gaacaagtcc caagctatga
    10261 cgatcaggaa ctaaaaaggc tgtgtgataa agaccataag ccttatttgc tggtaaaggt
    10321 gtttgtcgta actctaagat aacggtttta ccgtctgtag tcaattgacg agatgtcgtg
    10381 tcttgtgaga gaacctgtaa accgataata cttgtgtaaa aggttgtcat ctttgctaga
    10441 tcggtaacat ttagagaaac cgttcctaaa gagatggttg agttgtaagg gtatgtcatc
    10501 ctattacctc caaaaactaa ttaaatctat cataaccaat cagtttcaaa aagaaaagta
    10561 ggcacaaata agtggtatag gtactaaaaa gtaactcatt tatcagccct atcttgtttc
    10621 tgttctctct aatagtctat aatgggttat aagttacaaa aagatactaa gaggagctgc
    10681 tgcctatgct gaaaaaaaag accggcttgt cccgtagaaa cgaccttatc ggtaataaat
    10741 agaaattgtt aatattaaga gacttgctaa aggggacctt gcgttttggg cagttgaagt
    10801 cctcaatagg ttcggtcagt caaaaggtac ttactgccca attaagggct atggaagcag
    10861 acggattggt tcatcgggaa gtgtatgcag aagtgccacc tcgggtggag tattccttaa
    10921 cagaaactgg gttgagctta gctcctgtta ttgaagcgat gtcggattgg gaccaaactt
    10981 accaagaaaa acatgccgat ttatttgaag aaggctagag gaaagagttg tccgagcata
    11041 ctgagactta gagaagctga gagtttttta aaatgatatt atcacattct ttacagtttg
    11101 ataaaattac tttttttcta caaaaagact tgcgctcatc tcacgaatat gataatatag
    11161 tctcaagtct gtttgagaaa acagaagctc aggtcaagta agtgcacact tacaataaca
    11221 cagttgataa tggggaaact cagagtcaag aaaaagaaaa gcaagccttg cattttgcaa
    11281 ggcttttttc tgtctttatt ttggtctgcg ccgagcaaaa tctaaaaatt taaatttttc
    11341 cagtttatgg cgactctcgg tgaattggaa ttggttatta ttggaaaggt agactttgga
    11401 tttgacggaa acaacatgtt ggtctgatcc aaggtcaagt aaaattttat cacgatcggt
    11461 tatttggtca atggtaacct ctttgagggc aaagtcaatg gcgagatgga gttccttttc
    11521 caaatattga taaatagaat gctctgcgat ttcccttgtc attattggca ccaaagtttt
    11581 actaaggtaa tcaatgtcta agacggaagc cacaccctca acaacgcgtt ggcgtgtaac
    11641 acgccagacc aagctgtttt tgctaaaacc ggtcaatttt gaaagtgtct catccacaat
    11701 cagtttatca atggcaatga cgttggtctt agaatctaga tttgagtaag agacgagttc
    11761 ctgatagcta gttagttctg agatggggaa catgatctga tgatgcttaa tcacttgggt
    11821 gccacgtcct tgttttttga ggataagacc tgcctttgtg agaagtgaga gagccttgcg
    11881 gacggtatct cggctagctt ggtattgttg actcaattct atttcagtag gtaaaaaatc
    11941 cccttctttg taaaagtctt tgtttatttt tgtttcgagg tctttataaa tacgttcata
    12001 ctttgtcata gggtaaatta cctttccatt tgtctatttt tttacagaca acacctttta
    12061 ttttaccaaa ataatggctt ttttggcaca aacaacttgc agacaaattt gcaatcgatt
    12121 acaataaagg tgtcagtcag attctatcta agaatttgaa tatttcattt tgacgttgct
    12181 tgttaaaagc aactagaaca aaggactagg ggatgtcaca tgggaaaatt tgaacaggat
    12241 gctaaaagtc ttctaactgc tattggcggt aaagaaaaca tcaaggctgt cacacactgt
    12301 gcaacgcgta tgcgttttgt tttgaatgat aataataagg caaatgtcaa agagattgaa
    12361 aaaatctctg tagttaaagg gacatttacc aatgctgggc agtttcaggt aatcattggt
    12421 aatgatgttc cagtttttta taatgacttt acagctgttt ctggtattga agaggtgtct
    12481 aaagaagctg ccaaatcagc agctaaaagt aatcaaaatg ccttacaacg ggtgatgacc
    12541 atgttggctg agattttcac acctattatt ccggcgatta ttgttggggg gcttatttta
    12601 ggtttccgta atattttgga gagtgtgcct tttgaatttc ttgggcagca ggtcgaaaaa
    12661 gggaaattag tttttgatgc agctggggat cctgtttgga atacgattgt gagggtatct
    12721 cctttctggt caggggttaa ccatttcttg tggttaccag gggaagctat tttccacttc
    12781 ttaccagttg ggattacttg gtctgtgacg cgtaagatgg gaaccactca aattttaggg
    12841 attgtccttg gtatctgttt ggtgtcgcca caattattga atgcctatgc ggtggcagga
    12901 acgcctgctg ctgagattgc caaaaactgg gtttgggatt ttggtttctt tactattaat
    12961 cgtattgggt atcaggcaca ggttattcca gcccttttag ctggtctgtc ccttgcttat
    13021 cttgaaattt tctggcgtaa acggattcca gaagtggttt caatgatttt tgtgccattc
    13081 ctttctttga ttccagcttt gattttagcg catacggtat tggggccaat cggttggact
    13141 attggtaaag ggatttcctt tgttgtgtta gctggattga ctggtcctgt taaatggcta
    13201 ttcggtgcta tctttggtgc cttgtatgct ccgctagtta ttactggttt acatcacatg
    13261 acaaatgcca ttgataccca attaattgct gatactgcaa ctcgtacaac tggtttgtgg
    13321 ccaatgattg ctctttcaaa tatcgctcaa gggtcagccg tttttgctta ctatttaatg
    13381 aatcgtcatg aagaacgtga ggctgaaata tcgcttcctg cagcaatttc tgcttacctt
    13441 ggggtaactg agcctgcctt atttggggtt aatgttaaat atgtttatcc ctttgtagcc
    13501 ggaatgattg gctcaggtat tgcgggtctc ttatcaacaa cctttaatgt tcaggcaaat
    13561 tctattggtg ttggtggctt accaggtttc atggctatca atgtgaagta catgattcca
    13621 ttcttcatct gtatggcagt agccattgtg gtgccgatgt ttttaacctt ctttttccgt
    13681 aaatcacata tcatgactaa gacagaagat gaagctaaac tacctgagac acccgtttcg
    13741 gaggctcctg cagcaactgc tccacataag actatgcaag gaacagttat cactttaacc
    13801 agccctttaa cgggtgaagt taaagcgttg tctgaagctg ttgatcctgt ctttgcacag
    13861 ggagttatgg gccaaggtgc tcttcttcaa ccgacagaag gggtgttagt agcgccttgt
    13921 gatgctgaag tatcggtctt gttcccaact aaacacgcta tttgtttggt gacgactgaa
    13981 ggtttggaat tattgatgca tattggcatg gacacggtta acttagatgg tcaaggattt
    14041 gaagctttgg tgaagcaagg tgatcaggtt aaggctggac aaacattgat tcaatttgat
    14101 atagcagcta tttctgaagc tggatacgcc actgaaacgc ctcttgtggt gactaatcaa
    14161 gatgctttta cggtaactgt tgaaggtagt ttaccgcgtc agattaaggc taatgataag
    14221 ttagcagtag cgatgaaaaa gtaggtttac tagaagaaaa cgttcaggaa ctgagatcag
    14281 ttcctgaaac tattttaggg aggaaaactc atgacaattg ataaaaagaa agtcgtctat
    14341 caaatttacc caaaatccta taaggacacg actggaaatg gtgtgggaga cttgcgaggg
    14401 atcattgata aattgcctta cttacaagaa ctaggaatag atatgatttg gttgaaccct
    14461 ttctacccta gtccacaacg agacaatggc tatgatgttt cagattatac ggcggtcaac
    14521 cctgattttg ggactatggc tgattttgaa gatttggtaa aagctgctaa ggagcatcag
    14581 attgagttaa tgttggatat ggttttgaat cactgttcca cagaccacga gtggttccaa
    14641 aaagctttag caggagaccc ttattatcag gatttcttta tcttgagaga tcagccgact
    14701 gattgggttt ccaaatttgg tgggaatgct tgggcgcctt ttggagatac aggcaagtac
    14761 tacttacact tgtttgatgt gacacaggct gacttgaatt ggcggaaccc acatgttcgt
    14821 gaggaattgg ctaaagtggt taatttttgg cgagataaag gagtgaaggg gttccgtttt
    14881 gatgtgatta acctgattgg gaaagatgaa gagctggtgg attgtccggt caatgatggt
    14941 aagccagctt atacggatcg tcctattact cacacttatc ttcatgatct caatcaagcc
    15001 agttttggtc aggatgattc gtttatgacg gtaggagaaa tgtctgccac gactattgac
    15061 aactgtcttt tatacacggc ttccgaacgg gaagagttgt ccatggcttt taatttccac
    15121 catctaaaag ttgattatga gaatggtcag aaatggacta ttatggcttt tgattttgca
    15181 gcgctgcgag acttattcca tgcctggggt gaaggcatga gtcaaggcaa tgggtggaat
    15241 gccttgttct acaataacca tgatcaacca cgtgccctga atcgttttgt tgatgtaaca
    15301 catttccgaa acgaaggtgc gacgatgtta gcggcttcca tccatttgtc acgaggaacg
    15361 ccttacattt atatgggtga ggagattggc atgcttgatc cagattttga tagtatggat
    15421 gattatgtgg atgtggaaag tctcaatgct tactcaagct tattagtctc aggtaaaagt
    15481 gcaaaagaag cctttgccat tatcaaggcc aagtcaaggg acaatgccag aacaccaatg
    15541 caatgggatg ctagtgaaca tgctggcttt acgactggta agccttggtt agaggttggc
    15601 aaatcttatc gagacatcaa tgtcgaaaca gaaaaagagg gacgtatttt tcctttctac
    15661 caacgcttga ttgctttgcg gaaggaactc cctattattg ctgaagggga ctatagggct
    15721 gcttttaaag atagtcaggc tgtctatgcc tttgaacgcc atttaggtga ccagtgtttg
    15781 cttgttctca atcatttcta tgctggtgag gtcgaactgg aattacctcc acgttatcaa
    15841 catggacagg tcttaatcag caactatgag aaagtttcta tttgtgaaaa agtgatgctg
    15901 aaaccttatc agacacttgc tatcttagct gataactaac taaaagcctg aggttaggcc
    15961 tcaggctttt ggtgattgtc acgaaaaaag cagttttctc atatatttat ttttaaactc
    16021 ttattttttc taaataaaaa caattgagac aagttatttt aaccaaattt tggtacaatg
    16081 gaaaagatta taagtagagt ttaagataaa gattctacaa atttaaaatg atataaggag
    16141 atacgaatga caacttatca agatgatttt taccaggctg tgaatgggaa gtgggctgaa
    16201 acagcagtta ttcccgatga caagcctcga acaggcggat tttcagactt agcagatgaa
    16261 attgaggcat taatgctaga cactacagat gcttggttag caggggatca tgtccctgat
    16321 gatgcaattt tagcaaactt tgttaaattt caccgtttgg tggctgacta cgctaaacgt
    16381 gatgaagttg gagtaagtcc aattctccct ttaattgaag aatatcagtc cttaaaatct
    16441 ttttcagaat ttgttgctaa tatagcgaaa tatgaattgg caggtttacc aaatgaattt
    16501 ccctttagtg tggcaccaga ttttatgaat gctcagctga atgtgctttg ggcagaagca
    16561 ccaagcattc ttttgccaga tacaacatac tacgaagaag gcaacgaaaa agctgaggaa
    16621 ttgcgtggta tttggcgtca gtcgcaagaa aagcttttac ctcaatttgg tttttcaaca
    16681 gaagaaatca aggatctttt ggataaggta attgagctag ataagcaatt ggccaagtat
    16741 gtcttgtctc gtgaggaagg ctcagaatat gccaaattat accatcctta tgtgtgggct
    16801 gattttaaaa aactagctcc agagcttcct ttggatagca tttttgaaaa gattttaggc
    16861 caagtacctg acaaggttat tgttcctgag gaacgttttt ggacagaatt tgcagccact
    16921 tattactctg aagccaattg ggatttactc aaggctaatt tgattgtgga cgcggctaat
    16981 gcttacaatg cttacttgac ggatgatatt cgtgtggaat caggcgctta ttcgcgcgct
    17041 ctttcaggaa cacctcaagc tatggacaaa caaaaagcag ccttttattt ggcgcaagga
    17101 ccgtttagcc aagcgcttgg cttgtggtat gctggtcaaa aattctcccc agaagctaag
    17161 gctgatgtgg aaagtaaggt agcacgcatg attgaggttt ataagtctcg tctagaaacg
    17221 gctgattggt tagcaccagc cacacgtgaa aaagccatta ctaaattaaa tgttatcacg
    17281 ccacatattg gttacccaga aaaattacca gaaacctatg ctaaaaaagt gattgatgag
    17341 agcttgtcat tggttgaaaa tgcacagaac ttggctaaaa tcacgattgc tcacacttgg
    17401 agtaaatgga acaagccagt tgaccgtagc gaatggcata tgccagccca cttagtcaat
    17461 gcttattatg atcctcagca aaatcagatt gtctttcctg cggcaatctt acaagagcca
    17521 ttttattctt tagatcagag ttcttcagcc aattatggag gaattggtgc agtcattgcg
    17581 catgagattt cacatgcctt tgacaccaat ggtgcttcct ttgatgaaca tggtagccta
    17641 aatgattggt ggacacaaga agactatgct gcctttaaag agcgtacaga taagattgtg
    17701 gcgcagtttg acggcttaga gtcacatggt gctaaggtca atggtaaatt gacagtttca
    17761 gaaaacgtcg ctgatctagg tggggtagct tgtgctttag aagcggcaca atcagaagaa
    17821 gacttctcag cccgtgactt ctttattaac tttgcgacga tttggcgtat gaaggcccgt
    17881 gaggaataca tgcaaatgct agctagcatt gatgttcatg ccccgggtga actgcgaaca
    17941 aatgtcacct taaccaactt tgatgctttc catgagacct ttgatattaa agaaggcgat
    18001 gctatgtgga gagctccgaa agaccgtgtg attatttggt aattaggtag ttgataaacc
    18061 ttcaaatgct tgtgattata aaaatgactg attctgtgaa acacaggatc agttttttgc
    18121 ttccttattg gtgtccgttt tgacacaaca aaaagacaac cctcaggaaa gaaggttgcc
    18181 ttttttagac ttatcagaaa taagtgatta gttgttaagg gcagcagcca tagtagctgc
    18241 aacttctgat tcaaagtcgt tagctttttt ctcgatacct tcaccaactt caaaacgtgc
    18301 aaaagcaatc gctttagcgt ttactgagtc aaggtaagct tcaacagttt tgctgtcgtc
    18361 catgatgtaa acttgtgcaa gaagagtgta agcttggtca actttagtgt tgtcaagcat
    18421 gaagcggtcc attttacctg ggatgatttt gtcccagatc ttttctggtt tgccttcagc
    18481 agcaagttca gctttgatgt ctgcttcagc agcagtaatc acgtcgtctg ataattgagc
    18541 ttttgaaccg tatttcaaga atggaagtgc tggtttgtca accattgcac gcgattcgtt
    18601 gtcaagttcg atagcgtggt tcaattgagc aagttcatct ttgatgaatt gtgcatcaag
    18661 ctcagtgtat gaaagaacag ttggtttcat tgcagcgata tgcattgata cttgtttagc
    18721 aagagcatcg tcaccgcctt cgacaactga gataaccccg atacggccac cattatgttg
    18781 gtaagcaccg aagtgttgct catctgtttt ttcaatcaaa gcaaaacgac ggaatgagat
    18841 tttttctccg atggtagcag ttgcattaac gtaagcttca gcaagagttt cacctgaagg
    18901 cataacaagt gcaagtgctt catcgttgtt agctggtttg ccttcagcga taactttagc
    18961 agttgcgttt accaattcaa cgaattgagc atttttagca acaaagtctg tttcagcgtt
    19021 aacttcaaca acagcagcaa cgttaccatg aacgtaaacg cctgttaaac cttcagcggc
    19081 aacacggtca gcttttttag ctgctttagc cattcctttt tcacgaagaa gttcaacggc
    19141 tttgtccatg tcaccatctg tttcaacaag tgctttttta gcgtccataa cgccagcacc
    19201 agatttttca cgtaattctt ttacaagctt agctgtaatt tctgccatgt gtagtatcct
    19261 ccaaatgata tttgttttgg tttcaaaaaa cgagacagag cggtttgctt tctgccccgt
    19321 ttggttttcg attgttaaag acaaacaaag tttgccataa gagttaggaa ctctgtgcta
    19381 attaagcgtt gtcgccttcg acaacttcaa cgatttcttc gattgaatct gcttgagtgt
    19441 cagcttcaaa agcaacgtct gcatcttcac cttgacggcc ttcgataata gcgtcagcta
    19501 atttagcagt aattaattta acggcgcgga tagcgtcatc gttagctgga atgatgatat
    19561 cgatatcatc tggatcagcg tttgtatcaa ccatcgctac gactgggata ccaagttttt
    19621 tagcttcttt aacagcaatt tgttctttat gtgggtcaac aacgtacatt acgtctggga
    19681 tacgaggcat atcttcgata ccgcccaaga atttttcaag acgagcgcgt tgtttgttaa
    19741 gaagtgcaac ttctttctta ggaagaacgt caaaggttcc ttcttcttcc atacgtttga
    19801 tttctttcaa acgagcgata cgtttttgga tagttcccca gttggtaagc gttccaccca
    19861 accaacggtg gttgatgaag tattggcctg cacgcgttgc ttcgtcagca actgcttcag
    19921 cagcttgttt tttagtacca acgaacaaga tgacagcatc gtttgctgca gcatcacgaa
    19981 caaattcgta agcttggtca gctaatttta cagtttgttg aagatcgata acgtggatac
    20041 cgttacgctc tgtgaagatg tatttagcca tcttagggtt ccagcgacga gtttggtgac
    20101 caaagtgaac accagcctca agaagttgtt tcattgaaat tactgccatg agtagtttct
    20161 cctttataaa atgttttttc ctcttccaga cttcgacttg caggctaacc tagcggcaac
    20221 aagcccacaa ttggtctaga atgagtattt gccgcctaca cgaccctact atattatcaa
    20281 aaaaagaggt taaaagcaag gagaaatgct atggattccc ttatttttga gatgactagc
    20341 ttctttgttt attggtaagt gttaagacaa acttttgctc attttgggtg acacttgcca
    20401 aatcgtttta tttaagatat agtgaacttg actaattttt ggaggcgttt tcatgacgaa
    20461 gggtattcga tttcaattgc ttggcagtcc ccacattttt cttgatgaca aagaacaatt
    20521 ttttgccttt gccaaagcaa atgctctcct ttattactta gtggttaatg gatctgttag
    20581 ccgcgaggtg gcggcgagtc tactttggga aaataagaac acgcaaacag cgaaaaagaa
    20641 tttacgaaac gctatctacc aggtcaataa agtcttgcaa gctgatgtga ttatttgtcc
    20701 caatcgcaac ctgctggttt tgaataaaac acttgatatc aaaacagata ttaacctttt
    20761 tctagctgat ccgctagctc acttagaact ctaccaaggg gagtttttgc agggctttta
    20821 ccttaaaagt ggtgaggaat ttgatctttg ggtttcaaaa atgcgtatgc agtatgaaca
    20881 ggtataccta aaagcgtgtt accaaaaaat tgaagaaaag ctctctttag atgccattga
    20941 agatgtcgag gaacatttaa aacagcttat tgaacgtgat gaatttgaag agaaaaatta
    21001 tcagctcttg atgaggcttt atcagcaggg aaattgtcct ggtaaggtca tcgaaactta
    21061 ttatcagttg gctaatgtgt tggataagga gctagggatt cagccaagtt tgcaaagcca
    21121 acagatttat caggaagtgg tcgctaaaga tcgtaatgaa cgcaaaatca agcatttttt
    21181 gcgcaacagt aatcattttt tggggcggat tgatgatatt aagcagctgg aaaactattt
    21241 tgccaactgt ttggcctgcc aagaggtagg agctctgctc ttaattggtg atacagggat
    21301 tgggaaacga accctagcca gacaggtctt agccaatcaa acccaaacgt ttcaaattgt
    21361 cacagctaaa tgttttcgtg aagaggctat ggattcctta ttgccttggc gtaatatctt
    21421 agatggcctg ggagatttgg tgattcaaaa tcgcttattg accaccaaag cttggaaggc
    21481 tgctcttaaa cgctgttttc ctgtggcaac catttttcaa gaagataaca accaaccctt
    21541 tatcaaggac cacaccagct tgttggtttc ctttattgtt gatattttac aacatttggc
    21601 agaaatcaag gcgctggtaa tccttattga ggattgtcac tggatggatg aggacagttt
    21661 gaccttgttg caacgggtca tgaatcaatt ggtccactat ccgattgctt ttgtcttgac
    21721 caagcatcta ggaacgactc ctgagctcgg tctttgtttg aatgctttga tgagtcaagg
    21781 gcgtttagaa agcatttgtt tggagccttt taatcggcaa gaaagtttga cttatattaa
    21841 cagtcaactg ggtagtcagc cagtgacgga agaagaaatg gagcacctct atcaagccag
    21901 ccaaggcaac cctttctttt tgtcagaata cactcaggcc ctactgcgtc acgaaaaatt
    21961 tgtgccttta acgcctgcca ttaaggctaa gttgggtctt aaactagcta atctaagtag
    22021 tcgtgatgac gcattgttaa actatttgtc ttgttgtcgg aggcctatcc ctctaaatac
    22081 actcgctcaa ttgatgttac tgcctttaga agaagtgatc gagatggtgg ataatctggg
    22141 gcactactat attttggtag aagaaagcgt aggagaggag gtgttgattt catttcgtca
    22201 gcgaattatt caactctata gttatgaccg tttatctttg tcaaaaaggc gtttattgca
    22261 cggacaaatt gccaaacggt tagaagattt actgcctatt ttgacaccaa gccctcactt
    22321 attagatgac attgcttacc attatcagga atcacggcag gtgattaagg ctttggaata
    22381 caaccttaac tatctagatg ctaccttgcc atttcagcat gagctgtttc ccatttattc
    22441 aaagagtatt ggctccttgg aaaagtcaga tcgtgaccat caacgcttaa tggaagagca
    22501 gtttgataag attcggcaaa gcattgcgga tttggaactg acctatgata ataaccgtga
    22561 tttccagcag ttgcttattc gtttttctta ccttgaaggc cgttatgata ttcgaacagg
    22621 gaggtatcaa gaagggatta aacacattca aaaggtcatc gctttggcaa ccgagctaaa
    22681 acaaccctcc ttcttgctag aaggctatcg ccagttaatt cattactgta tccaagtgga
    22741 aaacaagcca gaaatgcgtt attacactag tctttcattg gaggcagcgg ttgctgctaa
    22801 tcattttgag gccattgcga ttagtttgcg gttaaacggt ctctatcatt tgattattgg
    22861 ggagttaaat gaggcagagc gtctgcttca acagtcgatt gacttcttca aggtgacgcc
    22921 aggcttgcaa gctaactatg cgattcagat tgctgctgcc ttagattatt tgggggagat
    22981 tgcccagatt cgctatcagt ttgaaaaggc cgttacttac caaaaacaag ccattgcctt
    23041 gaccgaaaac aagccagctg agttatcagt gagtattttt tatattggat tagggatttc
    23101 ctacttttat ttagctgatt ttgaacaagc tgagcaaatc ttgagtttgg ctaaggaagc
    23161 tttggtcaat catagttatc cttggaaaga aacgcaactt gaaatttacc tggccatgat
    23221 tcaatggaaa aagggtaatt atcagccagc cttgacccta cttgattaca gagaaacctt
    23281 gatgtctagg tatcgcaatc cgcgagataa gggcttggtt ttctatttga tggctgtggt
    23341 caagtaccaa ttgatacgtc aaggagctac cctaagtcag caggaaaagg aaatggcaga
    23401 ccacctgttg tcagaatcct ttgagtatta ttatgagatt gctagtacta acctcaaccc
    23461 ttaccgagat tgtcatttgg tgagtgagtt gaacgatttg cgtcaacaat tatctgctaa
    23521 aagctaagga aaaccctctg attcacatca gagggtttta gttatgttgt gccataatct
    23581 gtacgaggta aaagataaag gtggctgcta aattggcggt gtggttatca atatcgtgtg
    23641 gtggtgaaac ctcaaccaca tcaaagccaa ctaattttcc gctagctgca atgtgttgca
    23701 aaactaagac ggcaagattt gggtcaacac cgagggactg gatagcacta accccaggtg
    23761 cagcaccaac tgagaaacaa tccatgtcga tagtcaggta gaccctttct tgcccttcta
    23821 agaaacggtc aatggctcgg cagacctttt gatggcccat ttggtagatg tcttgacctg
    23881 ttaaaaattg aatgcccttg gattttgcca caaagtcaaa taggaaaagg ttgttattat
    23941 gttcttgaat gcctaaaacg aagtatttaa agaggcgttt gtcagcaacc gcatcgtcaa
    24001 acatttgtcg aaagcctgtc cctgaattag ggcctgtttg gtcgtaaggc cttaaatcaa
    24061 agtgggcgtc catattgatg acagctaggt catcacttga ggataggctt tggcgtaggc
    24121 ctaagtagtg gccgtaggcg gtttcatggc cacctcctaa gacgatgggt ttgagattga
    24181 ggtcacacat tcgtttgatg gctttgctta aactgttttg cagttgttcc aaagagcgat
    24241 tggggccgtc aatgttaccc acatcgtaaa ccataacttg gtttcctaaa tgccaaggga
    24301 atttggcgag ctgggttcgt atggcagctg gactttcgac cgctccgaca cgaccattat
    24361 tgatataaac ccccttatca cttttaaagc caatcaaggc aaaatgtgtc ccttcaaatg
    24421 gggttagtga gctgtcgtta aggtcaagga aagtcatgac catgccccat ttggcagtat
    24481 ataagtcatc gtcgatccca ccatgataat agctagtggt ggatgggtag taatcttcta
    24541 gcatgcgcgt catctccttt aggattatga tagcaaaata aaacttacag tcaactctct
    24601 ataggctgtc atcactggtt tttagaaata gcagagcaat aaaatcgtct gcttttggtc
    24661 ccagttagtt agtctaaaga ggccatgacc tctgccacag cccctctagt taaagaagta
    24721 ccttattcac taaaattgga tactcaactc aactgcctgc tcaaccgctt cgaggaagct
    24781 tgggtcttca atgactgctg atgccttgtt tagttcatcg tagatttcga tgtgtttatc
    24841 gtgttcgata aagttgactt ccttgcggaa gagatcgtag gcaaccttag tccctttacc
    24901 tagttcatga ttttcaggtt tgagatcaag ggcttggcag gctgccatga tttcagtagc
    24961 cacgatgcgg cgagaatttt taaggatttc aaaggccttg cgagcagcgg tggtgcccat
    25021 gctgacaaag tcttcttggt tctcacaaga tgggatagaa tccacactgg ctggatgtgc
    25081 caaaaccttg ttttcagaag caagagaggc acaggcgtac tgggtaatca taaagcctga
    25141 attgagacct gggtatttga caaggaagga tggtagtttg ctgagctggc tattgaccaa
    25201 acgttccaca cggcgttcag aaacatttcc aatttcagaa atggcaatgc ctaagaagtc
    25261 aaaaggctgt gccattggtt ctccgtggaa attacctcct gaaataacgt gaccatcttt
    25321 acagataatt ggattatctg tgacagaatt gatttcaatg tcaactttgg atttgacata
    25381 ggcgatactg tctttgctag ccccatgaat ttgagggatg cagcgcaagg tgtaagggtc
    25441 ttgcacacga gattgagtag ctatggttgt gttttggctg ccttcaagga ggtttcggat
    25501 attgcgggct gttgccaact ggccgctttg tgggcgaatg gtgtgaaggt tttcttcaaa
    25561 tggactagta atcccgttat gcacttcaag ggatagggca ccagctaggt ctgacagttt
    25621 caataattga atggcgtcat aggttgcaag ggcaccgact gcagtgagaa cagttgttcc
    25681 gttgataagg gcgagtcctt ctttagcggc taaagaaatc ttgtcaatac cagctttatc
    25741 aagagcttct tgaccagaaa gaagctctcc tttgtagtaa gctttcccta gaccaagcat
    25801 aggaagcacc atgtgagcaa gcggcgccaa atctcctgaa gcccctagag accctttttc
    25861 aggaatgtaa ggatgaaccc ctttattgag cagttccaac agtttttcaa tggtggatag
    25921 acgaatacca gaataccctt tgacgagaga gttgatacgg atcagcatga tagctctcac
    25981 ggcatcttct agcaatgggt caccaaatcc actagcatgg gtacgaatca aattttcttg
    26041 gagttgaact gtatcttctg gtgagatgct cacgttacaa agggatccaa aaccggtggt
    26101 caccccgtaa accacccgtt tttcactgac aatgtcatca acaattttac gagaggcatt
    26161 cacagcttca atagcactat catcaatgcg acaggctacg ccttggcgag caatcgcaat
    26221 cacgtcttcg agggtaaggc tttcgccatc taaattaatc actcttgtca tagtttttct
    26281 cctagatttg ttccttaggg ggcatttggt ccatttggtc catttggtgg ttacgtccgt
    26341 gcataaggta gtacacacta cttgcaatga tgacaccaac tgcaccatag acaaagttca
    26401 ttgggttgtc accccaaatc ataactaaac taacgataac tgcaagaatc gggataatag
    26461 ggccaaatgg tactcggaag atcacattag catcaggagc atctttccgt aatttcataa
    26521 cggctagtgc tgttggaatg tattggaaga agcggaaaac aacactgagt tttgctaagt
    26581 tttcaaatga gccagtgagt aggagtacaa tagcaattgc tcctgaaacc aagatagcaa
    26641 cgagtggtgc gccattttga ttttgcttgg caatagcagc tggtaagagc ccttcatcag
    26701 caatggcagc accgtaacgt ggcaccatga tggattctcc catgttaaga cctgtaatgg
    26761 aaattaaagc accgattgag accatccaag cgccagcagg gcctatcatt ttaacaaagg
    26821 catcttgaac aggtgcattg gtcatcatga tttgagagcc aagcatggca atggttccac
    26881 cgataatcag catatataag acagagacga tactgattga tcctaaaaga gcacgcggta
    26941 catttttttc agggtcacgc atttccccag cgacaataga gagggtttca aaaccgataa
    27001 agccatagaa gatataaaca gcagtattgg agatagcccc taagaggtta gtccctggtt
    27061 ccaactgaac aaatggggta aagttaggaa gcccgttttt gatgaagaaa agggtacaga
    27121 cacaaaaggc aacgattgga attaacttag caatggtggc tgtgatggtg acaattttag
    27181 aggttttcaa accagcgata ttcatcaaag atagtaagat gattaaccca atactaagtg
    27241 gaatgtgcca accttcaaag gcagggaaag taatgataaa cattctggca aacccagctg
    27301 ccatggctgc ccaagcgaag atggtaacgg tccaaccaag gaagccaacg ttaaagccaa
    27361 taaaatcacc aaaagctcgt ttggaatatt ggaaggctcc gccgtttttc ccaaaataac
    27421 cagagacttc tgcaaaacaa actgccaaca tgatggtcaa aatagctgtt ccaaacataa
    27481 cagcgatgga tgcagggcca aggcccttat aaatggccct aggtaagaga aaaataccag
    27541 agccgataac ggcattgatc ccgtaaagag tggcaccgct caagctaaac tttgcctgtt
    27601 ctctttcttg ttcgttcatg tgatttgacg ccataataat gctctccttt ttgtttgcaa
    27661 attgcgttca aatataatgg ataaggtcgc taggaaatga ggagatagtc ggtttaggag
    27721 ggtccttctt gcacctaacg atagtgatga gctattggtt agcgatgaga aataggtagc
    27781 cttttgtgat gatgtgtagt gatttcattg gagaagaaca ggcatgagta gtgtgatgcc
    27841 tatctttatc ccactaagtc ttataccata agcctgccca aacagctact ggattttggg
    27901 cgggacttgt ttgattgagg caaactttta gatctgaaag gctggcctcc tgctcgatta
    27961 ccaacaagtg attggcttca agctcttgat tcgcctgatt ggtcacagaa taagtcagtt
    28021 tgcgtagggc ataaagcagt tgacagtccg ctttaggtgc ctcaaatagt gtgtcagacc
    28081 agacgggtaa taattgccct tggtattggt catcatacat taaattgatg tcttggcaga
    28141 ttccacgact gacgattctg gtatcgcctt caaacgcgta gggttcaaaa ggagttaggg
    28201 aaatctcttt agcatgactc aaatcactca atgtgatggg cttgtctagg gtcattagaa
    28261 tcctgtgata gccatcaagt aaggtaaagg ttgtctgtcg tagggccaca gttgactttg
    28321 agaggcgata agagaattct ctctttttgt aatctccatc ttcgggataa aggaacaatt
    28381 ggttggtttc accgccagac cagtcagttt ggaggtaatc agagggcgct ttgatagtta
    28441 cctttgtcat ttgttctctc cttgtttcca attagaatag tcctgtgatg ttgccctcct
    28501 cgtcaatatc aattgtttcg ctggcaggta cttttggaag gccaggcatg gtcatgatag
    28561 cacccgtcag agcaacgata aatcctgctc ctgcggacac tttgaggttg ctaatagtca
    28621 ctgtaaagtc agttggtgcg ccaagttttt tggcatcgtc tgagaaggaa tattgggttt
    28681 tggccatgca aattgggtag ttgccaaagc cgaggcgttc taagtcagcc agttcacgtt
    28741 tggctgcggg ggtcaatcta atccccttac caccgtaaac cttggtaacg attttagtca
    28801 gtttggtttc aatgctatca tcttcctcat aaacaaagca gaattgattg tcttgctcag
    28861 ctagtgtcac gactttttca gctaatttac ggccaccagc tccgccattt gcccaaacat
    28921 cagaaatcac aacgtcaacg ccacgtttgt cgcaggcatc atagacagct tgtaattcag
    28981 catcggtatc aagcgggaat ttattgatcg ccacgacaac tggaaggcca tagacgtctt
    29041 ggatattagc caaatgtttg tcaaggttag gtaaaccatc cacaacggcc tgaacatttt
    29101 cagtagccag gtttgctttt ggcacccccc catgcatctt aagggcacga atagtggcta
    29161 ctaggacaac ggctgctgga cgaaggccgg acatgcggca tttgatgtca atgaattttt
    29221 cagctccaag gtcagcgcca aatccagctt cggtaacggc ataatcacca tatttcaagg
    29281 ctagtttggt ggcgaggaca ctattacagc catgggcgat attagcaaat gggccaccgt
    29341 gaatgagggc tggtgtgtgt tccagggttt gcacgagatt aggatgaatc gcatccttga
    29401 gcagtgctgc tagggcacca ccagctttca agtctttagc tgttacaggt tcgccttggt
    29461 aattgtaacc gatgatgatt ttttcaaggc gggctttgag gtcagagata ttttcggata
    29521 ggcacaggat tgccatgatt tcagaggcga cggtaatgtc ataaccatct tcacgaggta
    29581 ccccgttgac cttgccttgc aagccgtcaa caatatgacg aagctggcgg tcattcatat
    29641 ccaccacacg tttccaagtg atacgtctag aatcaatgcc taggctattg ccatggtgaa
    29701 tgtggttatc aatcaaggca gctaataagt tgttggcgac accgatagca tgaaagtccc
    29761 ctgtaaagtg gaggttgatg tcttccattg ggacaacttg cgcgtggcca ccgccagcag
    29821 ctcctccctt aaccccaaaa acaggaccaa gagaaggttc acgaagggca ataactgctt
    29881 tttttccaat ggcagaaaga gcatctacca gtccaacgga agtggtggtt ttgccttcac
    29941 cagctggtgt tggtgagata gcagtgacaa gaatcaattt accatcaggc ttatctttta
    30001 gggcaaccag ttgatgggca tcaatttttg ccttgtattt gccgtagaga cagagggctt
    30061 cctcgtcaat ccctaattga tcggcaacct tactgatagg ttccatagtg acagagttgg
    30121 ctatttcaat atctgataaa accatagttg ctcctttact tgttaaacaa tatcgagaat
    30181 tttcgtgtag atgtcatcgg ccaagtgaca gcccttgtct agtaaggctt gccctttttg
    30241 gcgatagtcg gtaacaaagt cttcatcttt gatgccagac agattaatca aaacattcaa
    30301 ccaagcgcct tgtaaacctg cttttaagtt taaagcagca actcctaagt cgctagcagc
    30361 atttgtattg gacttgccga cagctgtctc agtggtttcg agtgcttcga ccatgagggt
    30421 catcatctca aaaggtgatt gtgctgctgt ttttaaagcc tcttgcatgg cagttcgtct
    30481 ggcagccttg tcttcgtcag tctcttttgg catatcaaaa acggcagaaa ccaggttgaa
    30541 ggcttcggta tctttgtcaa tggcatctag taagtcctgt tgtaagcgac tacttttggt
    30601 atgaaggtct tcaatgataa cttgataatc agcatacttt ttcttaccaa gggtcaattc
    30661 acagaccatc ttagtcaagg aaatgccatt agcgccagag agagcagcag cagaaccacc
    30721 acctggagca ggggcatctg agccaaggac tttagcgaaa tctgttaagc ttaaatcaac
    30781 taaacccata gagaacctcc taacctagca aatggttttc aagaacctgt ttatggtagt
    30841 caaagtcctc aacttgtaag tagtattcag ccacatcgat taaggccttg gctggcgcta
    30901 agccgatgac ttcagaacca ataacattca caccgtagcg acgcgcttca aatttgatgg
    30961 tttcaaaagt acggtaaaga gaacattttt caaagttaac catgttcatg gagacttggg
    31021 caatatgacg gtcttctaac atgacaccga tagccttaca atatttgtag ccaccacctg
    31081 aaccgcggat aattttagca attttatgag caatgtcgat attgtcagta tccaaattaa
    31141 cattgaaagc aaccaatggc atgcgagcac caacggcagt tactccagca gttgggtgaa
    31201 tcttacggtc tccgtaatca ggtgcccagt cctcttccaa cagtttttct ggcatgcctt
    31261 caaactgacc tttacggatt ttagcaaggt tttgacgttc tggacgtgtg gcagaatctt
    31321 cataaaggaa gatcggaatg tcaagttcac ggttaatccg ttctgcgact tgtttggaaa
    31381 tctcaacaca ttcttgtgta gtgatgtctt tgatcggaac gaatgggcag acatcggttg
    31441 ctcccatacg agggtgttca ccatgatgct tggtcatgtc aatgttttca gaagcgtatt
    31501 tcaccagttg gaaagctgct tcttgaatag actggtcatc tccaactaag gtaaacacgc
    31561 tccggttgtg gctcgcatca gaagagtagt cgaggagggt cactccagga atacttttgg
    31621 ccgtcgctac caagccgtcg ataacagcct gattttggcc ttctgagaag ttgggaatac
    31681 attcaacaat tttcgccatg ttaatctcct tttatgtcat tgagttactc attaagggaa
    31741 tgggttacct actttagata acgcttacat ttttagctag cagttattag tgaaataatt
    31801 gatctaccgc tgaagtcaca aggtcatcat cagccaagta tgggatagtg atgtgatcag
    31861 tacctgcatg gagacggttg tattcaatag cggtttcaat agcgtgctca tttcgggccc
    31921 agttacggcg agctacaccg cccatagtat cccaagcaat agcagattta ataatctcat
    31981 caatgcgttc gctgccatct aaaacaagtc cgaaaccacc attgatggct ttaccaatac
    32041 cagttccgcc accgttatga agagccacta aactcatacc acgcgcagcg ttaccagcgt
    32101 aacattgaac tgccatatca caggtgacat tggaaccgtc tttaatgttt gaggtttcac
    32161 ggaatggtga gtcagtacca gacacgtcat ggtggtcacg gccaatcatg acaggtccaa
    32221 tcttaccttc tcggaccaat tcattaaatt taagggcgat agtcacacga ccaatacagt
    32281 cttggtaaag gatacgggct tgtgtgccga cgaccaattg atttttctca gcatcacgaa
    32341 tccagttata gttatcacgg tcttgatagc ggcggtcagg atcgatagct tccatggcag
    32401 ctttgtcagt agccaccaag tcttcgtgtt taccactcaa gcagacccaa cggaaaggtc
    32461 catagccata gtcaaaaagc ataggtccca tgatatcttc cacataggat ggccagataa
    32521 agccgtcttt gtcgttacga ccattcttag aaatttctgt aataccagag tcgtaaacag
    32581 acttcataaa ggcattgccg tagtcaaaga aataggtgcc attttcagtt aacgtcttaa
    32641 tagcttcaaa atgccgtgcc aaggtatcat caaccatttg gtggaaggta tccttgtctt
    32701 ctgccaggag ccgggttctt tcgtcaaagc taatacctac tgggcagtag ccaccgtcat
    32761 aaacgttgtg acaagaggtt tggtcagaca aaagatcaac atgaatctgc ttgtcattga
    32821 cgtactctaa aaggtcaaca atattaccat ggtaagcaat cgaagtggac tccttagcat
    32881 ctatggcttt tcgggctaat tgcagagctt cttcagggct ctcagcaatt tggctaaccc
    32941 agccttgcga atgacgggtt tcaatccgag attggtcaac ttcagcaata atggcaactg
    33001 ctttagcaat ttcagcagcc ttaccttgtg ccccactcat gcctcctaaa ccagatgaga
    33061 taaagagttt accggtcaaa tcaccatcgt cagccactcc aagtttgaga cgaccagcat
    33121 ttaaaagggt attaaacgtt ccatgaacga ttccttgtgg gccaatatac atccaaccac
    33181 ctgcggtcat ttgaccatag ttggtgacac ccatctcttc agcgatttcc cagtctttca
    33241 tgttgtcgta ttcacccacc aaaaggccat ttgtaatgat aacgcgaggc gcttcaggtt
    33301 tggatttgaa gagaccaact ggatgaccag actcaaccac taaggtttgt tcatcagtca
    33361 tgacctctag gtattttttg attaattggt attgcatcca gttagcacaa acagaaccag
    33421 tttctccata agtaactaat tcgtaagggt acaaggcaat ctcaaaactc aagttattgt
    33481 caatcatgac ttgcatagcc ttggtggctg tacaagtgcc tttgtactcg tcaatcggtt
    33541 ttccataaat gcgatctttt ggtctaaagc ggtagccata aatacggcca cgggttttga
    33601 gttcttccaa aaattctgga atgacttctt cgtggaactt tgtaggtaca tagcgtaggg
    33661 cattttttaa ggcaatttcg gtttgggctt gggtcaatcg aaaacctctg tctggtgctc
    33721 ttcggatacc ttctttgaag acagtctttt ccggtaaaac atcgtctaac ttaacagtca
    33781 tagcggcagc tatgtcagtt tcactgtaaa atgacataga aaactcctcc tcaactcctt
    33841 tttattgtcg agattagtct aacttagtct agtctataaa aagtcaacca cgctttgaaa
    33901 tgcgaaaaaa gtctaaaaaa aaatcaaaac ctcatttttt gactaaaatt tgacgcttaa
    33961 tcagtacact tgaggtatga cagataaagt cagtcagagg ttaattgttg ttaccaaagt
    34021 tgcagagatc gcaactattg agtgggtgag gggggctagt aatggttatt aatcagttga
    34081 caaacgatgt taaaaaagga ggtttttatg gttgctgatg tcttattaac acattttaat
    34141 caactatttt gtctaaatga tccaggtcat cctttaactg gtcaagaaat gaaaaaagcc
    34201 actatcgttg aagatggcta tatagccatc aaagacggcc tcattgtggc tcttggttct
    34261 ggtgaaccag atgctgagct tgtcggccca cagactatta tgcgttctta taaaggtaaa
    34321 attgcaacgc ctggtattat tgactgtcat acccatttgg tctatggtgg cagtcgtgaa
    34381 catgaatttg ccaagaaatt agcaggggtg tcttacttgg atattttagc tcaaggtggc
    34441 ggtattttaa gcacggtgag ggccactcgg tcagccagct ttgacaacct ttatcaaaaa
    34501 tccaagagat tgctagacta catgttgctt catggagtga ctactgtcga agcgaaaagt
    34561 ggctacggcc ttgattggga aacagaaaaa cgccaactgg atgttgttgc tgctttagaa
    34621 aaagaccatc ctattgattt ggtgtctacg tttatggcag cccatgcgat tcctgaagaa
    34681 tacaagggga atcctaaggc ttatctcgat gtgattatca aggatatgct tcctgttgtt
    34741 aaagaggaaa atctggcaga attttgtgat attttctgtg aaaaaaatgt ttttacagct
    34801 gatgagtccc gctatctgtt aagcaaagcc aaagaaatgg gtttcaagct tcgtattcac
    34861 gcagatgaaa ttgcgtctat aggcggagtt gatgtcgcag cagagctcag cgcagttagt
    34921 gcagagcatt tgatgatgat aacaaatgat gatatcgcta agttgattgg tgctggtgtt
    34981 attggtaatt tgcttccagc caccaccttt agtttaatgg aagacactta tgcccctgct
    35041 cgcaaaatga tcgatgccgg catggctatc actctctcaa cagatagtaa tccaggcagt
    35101 tgcccgactg ctaacatgca gtttgtgatg caattaggtt gttttatgtt acgtttaaca
    35161 ccgattgaag tcttaaatgc tgttaccatt aatgcggcct actctgtcaa tcgtcagggg
    35221 aaggttggta gtttgacagt tggtaaagaa gcagatattg ccatttttga tgccccaaat
    35281 attgattacc cattttattt ctttgccacc aacttgattc accaagtcta taaaaaagga
    35341 caactcacgg ttgatcgagg tcgtattctt taaaaaattt caaaaagaag ctttgagcgt
    35401 tagctcaaaa cttcttttaa atatgctgtt ttattgacga atcaagtagt caaaggcacc
    35461 gatggcagca gtagcaccag accccataga aataatgatt tgtttataag ttgaatcagt
    35521 acagtcccca gcagcaaaga tgccaggaat attggttgaa ccatgtttat ccacaatgat
    35581 ttctccgcgg tcggttaggt tgacaccact atctttgagc caagctgtgt ttggaacaag
    35641 accaatttga acaaagaccc cttcaaggtc aaggtgtttg tcttcaccgc tatcacgctc
    35701 agtgtagtta agacctgtaa catggtcctc tccaacaatg tccttagtag caacattttt
    35761 gatgatggtc atattgttag tcttagctgc gcggtcttga agcactttgt cagctttaag
    35821 ctcgggcaag aattctaaaa cgtaaacgtg tttagcaaga ccagccaagt caagggccgc
    35881 ttctaatcca gagttcccac caccgataac agcaacatct ttgccttcaa agagtgggcc
    35941 atcacaatga ggacagtaag tcactccttt gttacggaat tcatcttcac caggaacatt
    36001 aatgttacgc catttggccc caagagctaa gatagcagtt ttagcttgta gaaccgcacc
    36061 attagctaga gtaacctcga tgttttcttt tttctcaata gaagtagcta gttgtgcttt
    36121 gataatatca acatcataag acttagtatg ggcctccact tcggccatta attttggtcc
    36181 ttcagtgtaa agggtaccaa tcatgttttc gatgccgacc gtttccatga cctgaccacc
    36241 aaaggtttca gcaagtaaac ctgtttttag tcctttacga gctgcataga tagcagcgct
    36301 attgcccgca gggccaccac caataacaag gacatcatag agtcctttat cagcaaaggc
    36361 ttcctcagaa agtgggccag cgatttgttc taagagttgc tcaatggtag cacgaccaga
    36421 agtgaattct tccccgtcta aaaagacagt agggacagac ataatgcctt tggctttcac
    36481 ttcatcttgg aacatgccgc cttctaccat agtgtgtgaa atcttgtcgt tcaagacgga
    36541 cataatgttt aaagcttgaa caacatctgg gcagttatgg caggttaagc tgacataagt
    36601 ttcaaaatgc aacggacggt caatggcctt gatgcgatca ataacatctt gatccacttt
    36661 tggagcacgt ccagatactt gcaagagagc aagaataaag gacgtcaatt cgtggcctaa
    36721 aggaagacca gcaaagacaa ccccactatc gtgacctttt ttcgcaacct taaagcttgg
    36781 ttgtcggtct aaagtgatgt tttcaataga aatacgctca gacatagcag ctatttcttc
    36841 cacaaagtct ttgacttttt gagactgctc attgtcacca agggaaactt gcaaaacaag
    36901 atcagcttct aacagggtga ggtattgggc aagttgttct ttaatatcag gacttaatgc
    36961 catagctttc ctcctaaaat ttattaaatt ttaccaacta aatcaagact tggtgtcaaa
    37021 gtttcagcgc cttctttcca tttagctgga caaacttcac ctggatgttt acggacgtat
    37081 tgggcagcgt gaattttatc aatcaaggtg ctagcgtcac gtccaatacc atcagcatta
    37141 atttccatca tttggataat accatctggg tcaacgataa atgttccacg ttgagcaagt
    37201 ccgtcttcgc caagcacttc aaaggcttgt gaaataaggt gtgaagggtc accaatcata
    37261 gggtatgtga tagtgccaac cacatctgag tcatcatgcc aagctttatg aacaaaatga
    37321 gtatcagtag agacagaata aacttctaca ccaagagatt tcagtgtttc gtattgctct
    37381 tgaaggtcac cgagttcagt tgggcaaaca aatgaaaagt ctgctgggta gaaacaaaaa
    37441 actgcccatt ttcctttaac gtcttcattt gtaacagtga tgaattttcc atcatgataa
    37501 gcttgagctg aaaattcagc aatttctttt ccaattagag acatatagtt gtcctccttt
    37561 tttatagttt tatacttgta ttataaaaga acaacaagat tatgtctact cagaaaccct
    37621 tgattttact gggaaatcag cgattgtttt ctgacaattc agttgtgaaa caaatcacat
    37681 taattaaaat gattctaaat aagctgaaga tgctgttaaa tcaaaggtta atttaattat
    37741 aatctacaga aaatataatt attattaaag cgtttacaaa aaactttttt gattccgtta
    37801 aggcaactta atattatggt tacctaatca ctaatattgt aacctatttt ggcatgagat
    37861 cagggaatgg ctgttatatt aattggatat gtcttgtgca aatagtgctt gacggatttg
    37921 tggaattagg gtaaaataat ctttgttgcg gcggtatagc caagtggtaa ggcacggctc
    37981 tgcaaaagct tgatcgtcgg ttcaaatccg tctaccgcct tttatataca aaacaagcct
    38041 tgattaactt cgtgaaaacg ttgttaaatc aaggttttta ttttttgcga caggataaaa
    38101 aaagagaaaa aaagaaataa agtcggtcaa aagtcggtca aatttcccga agatgtcttt
    38161 tatagcctga ttattaggta tgaaaaatac tatggccaaa attggtaaac gattgcaaat
    38221 aaaggtcaga gttcttaccc ccttaaacga tatgcgttaa aagttagttg aactgccgtg
    38281 cacctaacga tagacacggt gatgtgagag cgagtagagt tgaatctcta cttgtttatc
    38341 ttaccatagt cagctttata aagtaaccac ccattacaat gcaactatat tcttaatgtt
    38401 tttaagcatg ttattgacaa gtgttataaa atgtgttact cttagtgagt aaattagttt
    38461 ttgagttagt atttgtgttt caacatcttt atttctctct atttttacaa atgattttta
    38521 gaaaggaagt ggatgtatat ggcacaaggt acagtaaaat ggtttaacgc tgaaaaaggt
    38581 tttggtttta tttcaactga aaacggtcaa gatgtctttg cacatttttc agccatccaa
    38641 actaatggtt ttaaaacgtt agaagaagga caaaaagtgg catttgacgt cgaagaaggt
    38701 caacgtggac ctcaagcagt caatatcact aaattggcct aatctggtta aagtaactaa
    38761 agagaagcag atgttggaaa cagcaactgc ttttttgatt tctaccagtt acctttaatg
    38821 attaagagtt gcgtttaagg ccttgtattt gttataataa tagtcagttt tagtcaaaat
    38881 gtattgacgt ggtgctacta agtttttaga gtagcccgca agcaaaggag tgacagcatg
    38941 ccaaccaaaa atacttcaga cagcattgaa gagtatatta aagaattatt agctaagtca
    39001 ggaatagcag aaattaagcg gtccatgcta gcagattcgt ttcaagttgt cccaagtcag
    39061 atcaactatg tcattaaaac ccgttttacg gagagtcgag gctatgaagt agagagtaaa
    39121 cgaggtggtg gaggctatat tcgtattgcc aaggttcatt tttcagacaa acaccatctg
    39181 attggcaatt taatggcaac tattgaagac tgtatcagtg agcaagtttt cacggactcg
    39241 atacaattgc tttttgacga acacttattg acagagcgtg agggaaatat cattttggct
    39301 gtggcgtctg atgatgtttt aggaactgat ggttcaacta ttcgtgcacg aatgctctat
    39361 cgcttattgc aacgaattga cagaaaggga agcaattaat gattatgtat tcaacgaaga
    39421 tgcaagacat ttttagacag gcgcagttcc aagctgctcg ctttgatagc cattgcctgg
    39481 aaacttggca tgttttgtta gctatggtag ctgtagataa ttctttagca aatatgattt
    39541 taagtgaata tgatgcccaa gtcgccatag aagaatatga agctgcagct attttagcca
    39601 tgggcaaaac ccctaaggaa cagttgtctc gtgtagactt cagacctcaa tctaaaacct
    39661 tgactaactt gttagctttt gcgcaggcta ttagccaaat cactagggat caagaagtcg
    39721 gctctgagca tgtcttattt gctattttat tgaatccaga tatcatggcg agtcgtttgt
    39781 tagaaatagc aggctatcag ataaaagata acggcaatgg gcagccgcga ttagctgact
    39841 tgcgaaaagc aatagaacgt catgcaggtt acagtaagga aatgattaag gctattcacg
    39901 aactacgtaa gcctaaaaaa acgaaaacac aagggacctt ttcagatatg atgaagccac
    39961 caagtacagc tggtgagttg agtgatttca caagagattt gactgaaatg gcaagacaag
    40021 gtttgttaga atcggtgatt ggacgtgacc aagaagtatc tcgtatgatt caggtattaa
    40081 gtcgtaaaac gaaaaacaat cctgtcttgg taggtgatgc aggtgttggt aaaactgcgc
    40141 ttgcttatgg ccttgctcaa cggattgcaa atggcgctat tccttatgaa cttaaggaga
    40201 tgcgtgtcct agaattagac atgatgagtg tggtagcagg aacccgtttt cgtggggatt
    40261 ttgaagagcg catgaatcaa atcattgatg atattgaagc tgatggtcag attattcttt
    40321 ttgttgatga actacatact attatgggtt ctggcagtgg tattgacagt acacttgatg
    40381 cggctaacat tttaaaacca gcattatcgc gcggcactct tcatatggtt ggagcaacaa
    40441 ctcaagaaga atatcaaaaa catattgaaa aagatgcagc tctttcgcgt cgttttgcta
    40501 aaatattaat tgaagaacct aatacagaag atgcttatca gattttgatg ggcctaaaat
    40561 tatcttatga gacctaccat aatgtctcga tatcaaatga agcagttaaa acagctgtaa
    40621 aaatggcaca ccgttattta actagtaaaa atctccctga ttcagctatc gatttattag
    40681 atgaagctag tgctgctgtg caaaacatgg tcaaaaaatc agcacctgag actttaacac
    40741 caatagacca agctcttatc aatggtgata tgaaaaaagt atctcgcctc ttagctaaag
    40801 aagcaaaagg tcagatgaga aaaccaacac cagtgacaga agatgatatt ttggcaacct
    40861 tgagtaagtt atcgggaatt ccacttgaaa aactgacgca agctgatagt aaaaaatacc
    40921 tcaatttaga aaaagaactg cataagcgtg tgattggtca ggatgctgct gttacggcta
    40981 tttcaagagc cattcgtcgc aatcagtcag gtattcgaac aggaaaacgt cctattggat
    41041 catttatgtt tcttggccca acaggagtag gtaagacaga actagcaaag gcccttgcag
    41101 aagttctctt tgatgatgaa gcagcgctta ttcgttttga tatgtctgag tacatggaaa
    41161 aattcgcagc gtctaggctt aatggagcac ctcctggtta tgtcggctat gatgaaggag
    41221 gtgaactgac acagaaagtt agaaataaac cttattcagt cttgcttttt gatgaagtgg
    41281 aaaaagcaca tcctgatatt tttaacgttc tccttcaagt attagatgat ggtatattga
    41341 ctgatagtcg tgggcgtaag gtcgattttt caaatactat tattatcatg accagcaatc
    41401 ttggcgcaac agccctgcgc gatgataaaa cggtcggttt tggggtcaaa ggcattcacc
    41461 aagaccatca agctatggag aaacgtattt tagaagaatt aagaaaaact taccgcccag
    41521 aatttatcaa tcgtattgat gaaaaagtgg tctttcatag tctgacccaa gataacatgc
    41581 gcgatgtggt taaaatcatg gtacagcccc tgattactac attggcagaa aaaggtatta
    41641 cccttaaaat tcagcctttg gccttgaaac atttgtccga ggtcggctat gatgagcata
    41701 tgggggcaag accattacgt cgaacgctgc aaactgagat agaagataag ctatcagagc
    41761 ttatcctttc tcgagaattg acaagtgggc atacgctaaa aattggatta tcacatggca
    41821 aattaacgtt tcacatagct taatttccat ataaaaggtg gatcatcctt gatgtcacca
    41881 aaaaaagagg ttattcttac aaaaataact tcttttttct tgactatttt tgaccaagtg
    41941 ataaaataga atataaagtt agcactcgat gaacatgagt gctaacttta ctaaagattc
    42001 ttttattgga ggaaaatttc atgttaaaac cattaggtga ccgtgtggtc gtaagatttg
    42061 atgatgaaaa agagcagaca gtcggtggtt ttgtccttgc aggcactcat aaagagtcaa
    42121 cacgaaaagc gacagtcctc gctgtcagtg aaacgggtgt tcgcactatt acaggcgata
    42181 gcgtgctacc ttcagtttca gtgggtcaag aggttttagt tgaaaatggg catgatttag
    42241 aagtaaccgt agatgatgag aaagtttcta tcatccgtga atctgacatc attgctattg
    42301 ttacaaaata aaacgacaaa tctctaaata gaaagaagga ttgaatatgg caaaagatat
    42361 taaattttca gcagatgcgc gtgctgccat ggtgcgcgga gttgatatgt tagcagatac
    42421 cgtcaaagta acgcttggtc ctaaagggcg caatgttgtt cttgaaaaag cttttggttc
    42481 tcccttaatt actaatgacg gggtaaccat tgctaaagag atcgaattag aagatcattt
    42541 tgaaaacatg ggagcaaaat tggtgtctga agtggcttct aaaaccaatg atattgctgg
    42601 tgatgggacg actactgcaa cagttttgac acaagccatt gttcatgaag gactaaaaaa
    42661 tgtgacagca ggtgctaatc caattggtat tcgtcgaggc attgaaacag caacagcaac
    42721 agccgttgaa gccttgaaag ccattgctca acctgtatct ggcaaggaag ctattgctca
    42781 ggtcgctgca gtatcatcac gctctgaaaa agttggagag tatatctcag aagctatgga
    42841 gcgtgtgggc aacgatggtg tgattaccat cgaagaatct cgaggtatgg aaacagaact
    42901 tgaagtggtt gaaggcatgc aatttgaccg tggttacctg tctcaataca tggtcacaga
    42961 caatgaaaaa atggttgcag accttgaaaa cccatttatc ttaatcacgg ataaaaaagt
    43021 gtcaaacatc caagacattt tgccactact tgaggaagtt cttaaaacca accgtccatt
    43081 actcattatt gcagatgatg tggatggtga agcacttcca acccttgtct tgaacaagat
    43141 tcgtggtact ttcaatgtgg ttgctgtcaa agcgccagga tttggtgatc gtcgtaaagc
    43201 tatgcttgaa gacattgcta tcttgacagg tggtacagtg attacagagg atctaggact
    43261 tgaattaaaa gatgctacaa tgacagccct tggacaggct gctaagatta cagttgataa
    43321 agatagcaca gtaattgttg aaggttcagg aagttcagaa gctattgcta accgtattgc
    43381 actgattaaa tcgcaattag aaacaacaac ttctgacttt gaccgtgaaa aactacaaga
    43441 acgtttggcg aaattagctg gtggtgtagc tgttatcaaa gtaggagctc caacagagac
    43501 agctttaaaa gaaatgaaac ttcgcattga ggatgctcta aatgctacac gtgcagccgt
    43561 tgaagaaggt atcgttgctg gtggtggaac agcacttatt acggttattg aaaaagtagc
    43621 agctcttgaa cttgagggcg atgatgctac tggacgtaac attgtgcttc gtgctctaga
    43681 agagcctgta cgtcaaattg ctttaaatgc tgggtacgaa ggctccgtag ttattgacaa
    43741 gttgaaaaac agccctgcag gaacaggatt taatgctgca acaggtgagt gggttgatat
    43801 gattaaaaca ggaatcattg accctgtcaa agtaacacga tcagcgcttc aaaatgcagc
    43861 ttctgtagct agtctgattt tgacaacaga agcagttgtc gctaataagc ctgaaccagc
    43921 tgcgccagcg ccagcaatgc cagcaggtat ggatccagga atgatgggcg gcttctaagc
    43981 tctctatagc attaaggatt atgaaaaaga agttgagact aaaggtctgc ttcttactat
    44041 gaaaaaagaa caaagattgg atttcgactc atgatatccc atctttgttt ttttagttgt
    44101 gatataaaat gccaatcttt gtggttacag acttttaatg tattggaaaa tatattgttt
    44161 ttctttgtca tgtgctatca tggagccaat gaaaagttat tcccatatat gggtgttgga
    44221 gggaaatttt ggagagattt ttaaaacctt tagagaatca aagggattac gattaaaaga
    44281 tgtcgcaaag gctggtatat caacctctca gctgtcgcgt tttgaaaaag gggagacgga
    44341 tttaaccata tcgacattta tgctgatttt ggatgaaagt aacatgctca ttgatgagtt
    44401 tatgtatgct gtccatgatt ttcatcgtga cgacttaaat gaactcttat caaaaagtga
    44461 ggcatttcgt aacaactcaa gatagtgatg acttgaagca gttacttcat gctcaactag
    44521 catcaactga taagaaggag atgttcacgg atatcttttg gcatatccag catgtctaag
    44581 tctgctatgg catgctattt tgggagtccc tcacgcgact ctgtcagtag ctctccttca
    44641 aaggattcac atataaagtc gtaatagaaa tagcactctt tttttgtcag gcttgataaa
    44701 gctagaaata ccctttaatt gaaggtttaa agctgtcaga cctatctctt cttttagttc
    44761 tcataaagcc gcttcaaaga aagattcaca gggctcgact ttaccttctg gttggcccca
    44821 tcctgggaag ttatcgtgtt gtctatggag tcataaaatc atatcgttat gtttgacaca
    44881 catattgccc cagtctctaa ccgttgctat caacagattc accacctttt agtatagtat
    44941 aagaaaaaag gggtaaaaga ggtttcttgt tgcttttttg gcttaaggtt tctttaagtc
    45001 ttatctagta tactaatgtc attccttaat aggataagta tttggttgta gaagtatcgt
    45061 cttaaactaa cgctatctca acccgattcc catcttattc acccctccta taccgataag
    45121 gtctcacaaa gtgtgagacc ttattttttg acttcagctc tagttatgga gaaacttgtt
    45181 gatacaagct tttttgggtt atggtattat gatctattca agcctttctt gtttttgggt
    45241 ttttctttaa ccaacttggc ttcaatagct tttaagcgtt tgaaggtttt ttcagcgcga
    45301 tctagtgaaa tcttatcagc tttttcttga gcagctttgg ggtcactgac gactaagtca
    45361 ctgatttctt tggtgctttt gtcttgttcg gctatccagg ttttttccaa gcctttcatc
    45421 tcatcaatca ctttagttcc aaatggtttt ggatgagcag ccacgagatc attaatgtgt
    45481 gacaccgtcc aataccatga cttatcgtta tattgggtgc ttttttcttg ataggcttca
    45541 taggttctac tgatattgcc aaggtatggc aagtaagggg cgttacgagg actgccaata
    45601 gatagccaca tgacaccacc acccaattca gcagggatgt cttttttcag ttggaaaata
    45661 tgagcttcca tgacattagg atttgagatg ggataagcat aacctttaac agcttttttg
    45721 gattttggtt tacccttacc gtctaatgcc atctgatcaa gtggtttaag atccagcccc
    45781 tcaaaacgat tacgttgcag tttcatcgca tcttctagac taaaggtctt atcagtgctt
    45841 tggagcaact cataattgct gtctttataa gttacttttg aatcagggtc aagtgattta
    45901 atccctgaga aagagcgaga gcggttggca tcgtttagtg gtggattgta agatttggca
    45961 atatgaaatt taccatcaac ttcggtataa gatttggctt ttttagcgac tttttccaca
    46021 tcttctgagg caatcgtatt ttccttatcg ttgaaatcga catgtccgag atagaaggta
    46081 tttggaaaaa cagcgtattt atcatctgga aatttgatgg caacgtattg gtgaccagag
    46141 agaatttcca tgtaccagat gccgtctttg tcagccaagg taacaatatt tccttcagca
    46201 gctccttttt cagtgactat tttagcaatc aatgcgacac cttcacgggc tgttttgaca
    46261 cttggtaaaa tgacactggc catagatgat tccgctaagc catttttgac gtaaggatca
    46321 attttttgga tggcatcatt agctgaagct gatactgttg cagacataga gacgccaaac
    46381 tcattaaaac cagcttcgtc ataaacgcct ttgttaggtg ttacatcagg aatcgcacta
    46441 tagcgataag aatgctcagg caacgggtac tcaaaaccat tagagaggtc tttccatttt
    46501 tcgccagcag gattgtcctt tgctagacgt acaatgaaat ttttattatg gtgtggctca
    46561 agatcttctg ttcgaccata aagaagagaa ccgtctttgg ttaaatcttt gccaataata
    46621 aaaccagtac aagcataact aacactttga agcgaaaagg ctgtcagaat acttaaaact
    46681 ccaagtgata tttttttgtt tatcatgcga atcctcctag taaacgataa cgctttcaca
    46741 gacattataa aatgctcttt ttaaaaattc aagtctttta tgaagtgttt tgaaattgtt
    46801 agctatctaa atattatgag aattctctct tgaattttga cttaacggcc cctaaaaacg
    46861 tataggcagt gaactatcta ggtttcttcg aaaatccatt agccatttat gatataatag
    46921 taaagaaaaa catagaaagt tggggtctgt tgatgaccaa accatttcat cataagaaac
    46981 taaaacaaat aactataata gctgcaacta gccttttttt attcctgatc ggtggtgcct
    47041 tttactactc taaaaatcat tgtattaatg cctatcttaa agctcgatca gcccaatcag
    47101 gaccagtttt tgagaatatc aaagcatatc tagtctggga tgatactaat gagcagatca
    47161 caaatgacga ggcgatgtat actaagttta gaaggtatag tcaaaaagaa ttgaggcaaa
    47221 aaaagcagga tttaaaagcc gctagtcaag atagtgccgt tcaagtaaag tctgttggcc
    47281 gtcgtttttg gatttttcct gattatcgga ttgccataaa acccatggat ttaacgataa
    47341 aaacgaatgt gcctcaagca gacgttcttt taaatcataa aaaagttgct gtttctgatt
    47401 cagaacagtt ctcagtcaag cttgatcggc taccaacggc agaatatacc gcaagtatca
    47461 gaggcaaaca caacgggcga aacattaaag tcaacaaatc atatgatggt gataatcccg
    47521 tgctagattt gagcgtgtct tttagaactt ttttggtaac aagcaatgct aagcaaggag
    47581 atctttactt cgatgataac catattggca cattaaaaga cggtcaatta caagtagaag
    47641 attaccctgt tacagaaaac gcacaagctt atatgaaaac aacattccca gatggtgagt
    47701 taagatcaca aaaatatgct ctagctgatg ttgaagaagg agcaaccctg gagattttag
    47761 ttacagatct tttagaagag gacaaagcag gggagctatt agtatcagct tttgatcagc
    47821 tgatgcacta cctcagtaca ggtcaagact catctaactt acgtagcgtc tttgaggcag
    47881 ggtctagcaa cgcattttat aggggattga aagagtccat aaaagcgaaa tttcagacag
    47941 atacaagaaa agccagccgt ctcaatattc catctatcct tttgacaaca atgactcaag
    48001 tgggtaaaac aacttacgtg cttgatttca cagctaccta cgaatttttg tatgacaagt
    48061 caacagatcc tgagcagcat acctctggac atattaatca agacttgact ggaaaagtga
    48121 ctgtaaaaaa agttggacag cattacctta tcagccagtc cggctccaaa aatattactg
    48181 ttgttaaaga ggacaatcaa ctcaaagcgc catctgtctt tcctgagtct attttgggaa
    48241 cgtggacagg ccaagccaat ggtttgagca tccatatgtc tctagcatca gatggaacaa
    48301 ttacgactaa agttgaagat caaaaaggca accgttctaa agaaactcgg acagctaaaa
    48361 ttagtaaagt tgaagacaaa ggcaatggtt tttatcttta tacgccagat cctggaagtg
    48421 acataagcgc cttagttcca gaaggaggat tggggggtgc aaatgtcaaa tatgcttatg
    48481 gtttcaaaat atctggtaaa acagcctctc cagtggtgtg gcaggcagca ttaacacatg
    48541 aatttgatta taccaagcca ctttcgggtg taactttgca aaagcaacca taaaggatgc
    48601 aaagccacaa agaacagtag aaacaatgtt atcactcaaa tacagtgcta tgaaaacaga
    48661 taaactcaaa aggctaggag attatttcct agccttttga gcgtttaaga ctgcgtcaaa
    48721 tgtagctgat ttagcttgca cgcaaatgtc ttcttgggtt agagggtgtt tcaaacgtaa
    48781 ttgataagca tggagcatca gtcgagcaca atcttttttt ccattagaat acaaaggatc
    48841 accaaataaa acatgacctt gatgggctaa atggactcga atttgatgag tccgtccagt
    48901 ttgtaattga caattgagta agcttgccgt tttgtggaag tttttgacta gagttacctc
    48961 agtaatagct ttcttgccat ttatcggatc gacaacacgt tttctgcggt catgtcgatg
    49021 acgaccaatt ggatgatggt aagttaccct aggactgtct aaggatccgt gaactagtgc
    49081 caaatattct cgatggatgt ctcttttttc taaaagacga ttaaggattg gtaagataaa
    49141 aggtgtttta gcaaataaaa tggccccact tgtttcctta tccagacgat gaaccacata
    49201 gcaggtctgt cccgtgtaag cagacacgtg gttgagcagc gccaactctg ttggatcatt
    49261 gccgtgtgtt ttcatccctt caggtttgtt aacaataatg atgtgttcat cttcataaag
    49321 gcaggttact ttttcggcct gccccatcac gataatcttt tcaggataat cttcgtgatc
    49381 aaaaaaaagt ttgacctgat caccgtattt aacacaactt tgccagttaa cagaatgacc
    49441 attaataaga acatgttttt tagttctcag aaaatgccta attttacggg gaattaacaa
    49501 ttgttcctct aataatgctt tgaccgtcaa ttcttcaaag ggatttttca gtgtgacagt
    49561 aaaccccttt gatggtttat ttgttgtctt cattgagcca gttatggtat ttttcaacaa
    49621 ggttgatagc catttgggtg gcaagagcag cagagaaagc ttcagtacct tcacgctcgt
    49681 cattagctac ctccaagcga gtctcatcgt aaatggcttt tagactttct gcggataagg
    49741 tttctttaaa agcttggaat ttattcattg gttaaacccg tccttctatg tttaatgtga
    49801 gctcctgatt aatgcaagga attcaatgct attatagcat gtttctaatc aaaacgtgcc
    49861 actcaaaaag gtaaaaacgt tattttgcta atccatctaa taagaaagtg tcttaaataa
    49921 gacctcttga tagagtttgt aacagaaatg atatgaaact aggtgctaac gcagaaatag
    49981 aaaacaacta acgtgttgcg aagttggaac agtcataaaa aatagcaaga taaaacttat
    50041 caacacatag ttacctaaga cgatgagtca atcaggtatg ttctttcaaa acaaccccat
    50101 gaggttgaac gacgtatcgg aaaaatacgg attagtttgg ccttatgata ggtatttctc
    50161 tatcgtaaaa gaagtcaacc aaaggttttt aatataaaat attaagaaaa attgttataa
    50221 ttatgataaa aacataatcg taaaatagag gaaaaacaat gaaaacaatt agacgttatg
    50281 atgttaacga agatagaggg catacaggcc ttgtagaagc aggagatttc tattatttaa
    50341 actattgtgt cggcaatgtt ggacaagaca ttgaaagtca gattaatgga gcctttgatg
    50401 agatggagcg ccgattagca ttggtggggc tcacattaga tgcagttgtt caaatggatt
    50461 gtctatttcg agacgtttgg aacatacctg tgatggaaaa aatgattaaa gagcgcttta
    50521 atggcagata tcctgctcga aaatcgattc aaacggaatt tgcacatcac ggtggaccac
    50581 aaggactact ctttcaagtg gatggtgtgg cttattcaaa acatatttcg atgacctaat
    50641 caaggttact ttaagatcat agtggtataa taacgttatg agatttctag aacttttaca
    50701 aaagaaattt tttcctaaag catatcagga aaaacaattc ttaatgcatc aaaaagcgcg
    50761 tttaacgcca caacacaatc aaaagcagta ttcgccaaat gcccatcatt tggactcatc
    50821 agctaccaaa aactcagaac aagaccctgc aatagctctg caacgcagta gagcctatga
    50881 aggaagtcct aaaagtcggc ccgcttggtt gcaaaagctg gaagctgttt tgccgtctcc
    50941 tcaacatcca attcggcgtt tttggcgccg ctatcacatc ggaaaactgc taatgattct
    51001 gattggaact cttgtcttac tcttaggatc atacttgttt tacttatcaa aaacagctaa
    51061 agtatctgat ttacaagatg ccttgaaggc tacaacggtt atttatgatc acaaaggaga
    51121 gtatgcaggc agtttatctg gtcaaaaagg gagttatgtc gagctcaacg ctatttcaga
    51181 tgatcttgag aatgctgtta ttgccactga ggataggact ttttacagta atagcggtat
    51241 taatcttaaa cgcttcttat tggcggtagt tacggcgggc cgctttggag gtggctcaac
    51301 gattacacag caactggcta aaaatgctta tctctcacaa gatcagacaa ttaaacgaaa
    51361 ggccagagag ttttttttgg cgttagagtt gaccaaaaaa tacagtaaaa aagatattct
    51421 tactatgtac cttaacaact cctattttgg aaatggagtt tggggagttg aagatgccag
    51481 tcaaaaatat tttggaacca cagctgctaa cttaacattg gatgaagctg ccacattagc
    51541 aggtatgctc aaaggacctg aaatatataa cccttaccat tctctaaaaa atgctactca
    51601 ccgtagagat actgttttag gagcgatggt tgatgccaaa aagattaccc aaacaaaagc
    51661 tcagcaagct agagcagtag ggctaaaaaa tcgcttagct gatacttatg ttggtaagac
    51721 agatgactac aaatacccat cctactttga tgctgttatt agtgaagcaa tagcaactta
    51781 tggtctttca gaaaaagaca ttgttaataa tggatacaaa gtttacaccg agctagatca
    51841 aaattaccaa actggcatgc agacgacttt taacaacgat gaactatttc ctgtttcagc
    51901 ttatgacggt agctctgctc aagcagctag tgttgcttta gatcctaaaa caggaggtgt
    51961 tagaggtctg attggtcgtg tgaatagtag tgaaaatccg actttcagaa gctttaacta
    52021 tgcgactcaa gcaaaacgta gtcccgcatc aacaatcaaa ccactcgtgg tttacgcgcc
    52081 agccgttgct tcaggatggt caattgaaaa agaactacca aataccgttc aagatttcga
    52141 tggctatcag ccacataatt atggaaatta tgaatcagaa gatgttccta tgtatcaagc
    52201 attagcaaac tcttataata ttccagcagt ttctacattg aacgatatcg gaatcgataa
    52261 agcctttacc tatggtaaaa catttgggtt agatatgagc tctgccaaaa aagagttggg
    52321 ggtagcttta ggtggcagcg tgacaaccaa tccattggag atggctcagg catatgctgc
    52381 ctttgccaat aatggagtaa tccatcctgc gcacttgatt aaccggattg aaaatgccag
    52441 gggtgaagtg cttaaaacct ttactgataa ggctaaacgt gttgtcagcc agtctgttgc
    52501 agataagatg acagccatga tgctaggtac cttttcaaat ggaacagcag tcaatgctaa
    52561 cgtatatggc tatacactag ctggtaaaac agggacgaca gaaaccaact tcaatcccga
    52621 cttagcaggc gatcagtggg ttattggtta tacgccagat gttgttatta gtcaatgggt
    52681 aggatttaat cagaccgatg aaaatcatta tctaacggat tcaagtgcag gcacggcttc
    52741 agctattttt agcactcagg catcttacat tttgccttat accaagggca gccaatttca
    52801 tgtagataat gcttacgctc aaaatggtat ttcagctgtt tatggagtca atgaaacagg
    52861 taatcaatca ggagttgaca ctcaatctat tattgatggt ttaagaaaat cagcacaaga
    52921 agcttcgcaa tcactatcaa aagcagtcga tcagtcaggg ttacgtgata aggcccaatc
    52981 tatttggaaa gagattgttg actattttag atagcttgca gtattttaga gatcgtgtta
    53041 aaataatagt tacggaggcg ttatggcaca gaaaaaagcg agtctagcgt gtgtcgaatg
    53101 tggcagtcgt aactactcta tcggagtgag tagcacgcca aaaccaacac gtctagaagt
    53161 aaataaattt tgcaaatact gcaaaacata taccttacac aaagaaacac gttaaaaagg
    53221 agagcctgat gggattcatt agcgggactt ttaaagtctt aaaagacaca acatggccaa
    53281 atcgtaaaca acgttggaaa gattttatct cagttcttga gtacacagct ttctttacgg
    53341 tgattatcta catctttgac cagctcttag caaagagtgt attagcactg attaatttat
    53401 tctaggtcaa gattggtaga aatgataagc ttgcttggaa aagcctaggc tgggagtatt
    53461 cccagccttt tttgtagtat caataatcta attagtaagc ttttttaaag cccatactgg
    53521 tttgagcttt aaaaaagcat aaaggtaaag gcaatgtagc aacgatctct aaaccaagtt
    53581 cactaaatta gcttgtaaca gagtcatcgc ataaacagtc tggcctcact tgcttagcac
    53641 attaaaaata gcaatgaata ttatggttga ggaaaacagc ctgatagtct gctaaatctt
    53701 cgggatgata agccttgatc tcagccatct catactccct acctagaagt ttgtacttgt
    53761 tttctccaaa ttgatggaaa ggtaacagtt gcacttggtc aatctcaagc tgattaaaga
    53821 gctctgagaa ggctttagca tcgtctagtg aatcattaaa ttggggaata acagggatgc
    53881 gcaagacgat ttcttttcca gcttgaaagg cataatgaat atttttgata atcaagtcat
    53941 tacgaacccc agtcactttt tggtgtctga gctgattata atgtttcaaa tcggtataga
    54001 taaagtccac gtagtcaata agggtgacaa attgctcgtg tttggcaaag gcggtggttt
    54061 caattgcggt gtgaagacct gctgctttgg ctgcttttaa cagggctaag gcaaagtcaa
    54121 attgggcaaa gatttccccc cctgacaggg tcatgccccc acctgactct tcgtagaaat
    54181 caaggtcttt aaggacttct tcgatcacct cgtccacggt tttttcctct ccaactattt
    54241 tagtattaag cccatcactt gttaacatct gctcaggcgc tttttgttgg gattcgggat
    54301 tggcacacca aggacatctc aagggacaac cttttaaaaa aacggttgtc cgaataccag
    54361 ggccgtcatg aatactaaaa tgttggatgt tgaaaacaat accgcgatca gtcataagtg
    54421 tgaattcctt tcgttgtaaa accatcatac cagataaacg taaataaatc aattacgaat
    54481 gaaagtaaat atcccttttc ttttaagaaa ataactggta caatgaaagg gaggtgaatg
    54541 atgaatcgat tagaacgtat tattcaactg gtttcccaga agaaaaaaat agatgttaac
    54601 agtttatcag agcaattaga agtttcgaaa gtaaccattc gaaaagacct tgataagctt
    54661 gaaagtaagg gcttgttgcg acgggaacat ggctatgcgg tgctaaacag tggcgatgac
    54721 ctcaatgtac gcttgtccta caattacaac ataaagcgac ggattgcaga aaaagcagct
    54781 gaattggtgc aagacaacga taccattatg attgaatctg gctcaacctg tgcccttttg
    54841 gcagaagtgc tttgccagaa caaacgaaat attaaaatca ttaccaattc gtgcttcatt
    54901 gccaactaca ttcgtcaata tagtagctgt caaatcattt tactgggcgg ttattaccag
    54961 cccaattcag aggtgactgt tggtccttta ttgaaagaaa tgatatccct ttttcatgtc
    55021 aatcgtgtct ttgttggaac agacggtttc aacaaagatc ttggctttat gggcaaggac
    55081 atgatgcgct cagaaggggt gcgttacatg gcagatgctg ctgaggaagt ggtgattttg
    55141 accgattcca gcaagttttc aaaaaccagt ctggtacacc agttgtcatt agctgatgtc
    55201 aatcgcgtca ttacagacca agcactagac aagcaaacac aagagttatt aagtgctagt
    55261 ggtcttgttc ttgattttgt ttcttagaaa ataggtggct agatgaaaga agaacgcaga
    55321 cggctccttg ccaaggtggc ttacttgcat tatgttcaag gcaagagcca aaccttgatt
    55381 tcaaaggaaa tgaatatcta ccgaacaacg gtttgtcgga tgttagcaaa agccaaggaa
    55441 gaaggcattg ttcggattga aattgccgac tatgatgctg atttatttgc tttagaagaa
    55501 tacgtgcgaa agcagtacgg cttggaaaaa ctagaccttg tgcccaacca ggttgaagat
    55561 accccaatgg ataccttgac aaatgttgct aaaacagcag ctgaggtttt tagacatgtt
    55621 gttaaagatg gcgataagat cggtctgtcc tggggagcga ctctttcttg cttgatggat
    55681 gagttaaatc caaaagcgat gaaagatgtg tttatttatc ctttggcagg aggacctagc
    55741 catattaatg ccaaatacca tgtcaatacc ctggtttacc gcttggctcg catctttcat
    55801 ggtaatagcg cttttatgaa cgctatggtc attcaagaag acaaacactt ggctaaggga
    55861 atcttacaat ctaaatactt taacgacatt ttaacaagct gggaccagtt agatcttgcc
    55921 ttagtaggaa ttggtgggga gcctaatagc cttgagcaga gtcaatggcg tgatttatta
    55981 accagctcag atcatgacca actcaaatat gaaaaagccg ttggtgaagt ttgttgccgt
    56041 ttctttgatc aggcaggtca gccagtttac acgggcctac aggatcgaac tattggtatt
    56101 tcgctagaac agttgaggcg tgtccccaaa acaatggctg ttgcaacagg taaacacaag
    56161 gctaaggcaa tattggcagc cttaaaagca ggttttatca attatctagt gacggataaa
    56221 gagaccatgc tagctgtttt agcgttagat gaagatattg atcttaataa cgttcttctt
    56281 taatagaaat tcaaagatac tatgatattt atagaggccc aagaccaaac ggtcagggct
    56341 ttttttgttt gatgtgttga tgaaacagag aatgctcaaa tgtgcagtta atgtatcggc
    56401 acaaaagtgc attaaacaaa atatagcaca aaatatattg accctaaaaa caaaaatgat
    56461 acaataaact taccaacgaa atgtaaacga ttacaaacac aataacatca ccttcgaaaa
    56521 aaagactcat tgccgttaca tcacatgaaa aagaaaaaaa ggagacacca atgcaagtta
    56581 ttgtaccaga ccaaatcatt atgggcttaa ttttaaatgc aggcgatgcc aaacaacata
    56641 tctaccaagc tctgaaatgt gctaaagagg acgattatgc cactagtgaa aaagagatgg
    56701 ccttagcaga tgatgcctta ttagaagccc acaatttaca gacccagttt cttgcccaag
    56761 aagctagtgg taataagtca gagattacag cgctttttgt tcactcacaa gatcacttga
    56821 tgacgaccat tacagaaatt aatctcatca aagagattat tgaccttcgt aaagaattgg
    56881 caaccaaata atatttcatt cataaaaagg agattgacat gattaaaatt ggattgtttt
    56941 gtgcagcagg attttcaacc ggcatgttgg tgaacaacat gaaagtagct gctgaaaaaa
    57001 aaggcattga ctgtcagatt gaagcctatg ctcaagggaa attagcggac tatgcaccat
    57061 tacttgatgt ggcactttta ggcccacagg ttgcctatac tctggataaa tcagaagcta
    57121 tttgtaaaga caatgatatc cccattgcag ttatcccaat ggctgattat ggaatgttag
    57181 acggcaacaa ggtgcttgat ttagccctta gccttgttaa agaataggag tcaatcatgg
    57241 caaaaatgaa tatgcaaaac atcatcatgc caatcatgac atttgtgaat atgcgcggca
    57301 tcattgcctt aaaagacggt atgttagcca ttttaccttt gaccgttgtg gggagtcttt
    57361 tcctgattgc tgggcagatt cctttccaag gggttaacga tgccattgct agtgtgtttg
    57421 gtgctgactg gacagaaccc tttatgcagg tttatcatgg aacatttgct attatggggt
    57481 tgatttcctg ttttgcaatt ggctattctt atgctaaaaa ctcaggtgtt gaacctctcc
    57541 cttcaggggt tctatccttg tcagccttct ttattttatt gagatcatct tatgttccag
    57601 cagaaggtga agctattgga gatgctatca gtaaggtttg gtttggtggt caagggatta
    57661 ttggtgctat tgtgattggt ttaacggttg gagctgttta cacaacattt atccgtcgtc
    57721 atatcgtcat taaaatgcca gatcaagtgc cacaagctat cgccaaacag tttgaagcca
    57781 tgattccagc ctttgtgatc tttaccttgt caatgcttgt gtacattatt gccaagtcag
    57841 taacaggtgg tggcaccttt attgaaatga tttatgatgt cattcaggta ccgctgcaag
    57901 ggttaacggg ttctctttat ggcgcactag gtattgcctt ctttatttcc tttctttggt
    57961 ggtttggcgt gcatgggcaa tctgtggtca atggaattgt cactgctctt ctcttatcaa
    58021 atctagatgc caataaggcc ttgatggcag caggagagtt atctctagac aagggtgccc
    58081 atattgtgac ccaacaattt ttagactctt tcttgattct atcaggttct ggcattacct
    58141 ttggtttagt ggtagctatg atctttgcgg ctaaatccaa acaatacaag gctttaggca
    58201 aggttgcagc ttttccagcc ctctttaatg ttaatgaacc agtcgtcttt ggttttccaa
    58261 ttgtgatgaa tccagtcatg ttcttgccat ttatcttggt tccggtcttg gcagctctca
    58321 cagtttatgg cgccattgct attggtttca tgcagccctt tgcaggagtg acccttccgt
    58381 ggtcaacacc agccattatc tcagggttca tggttggtgg ctggcaagga gctattgtgc
    58441 aaattcttat actcatcctg tcaacgttgg tgtacttccc attctttaaa atccaagata
    58501 atatggctta tcaaaatgaa caagctagtg aagagtcatg atttagcgtc caccaaattc
    58561 ttgagaccat ctccagttag aggtggtttt ttagaaaaag aagaacgact tatcaggcct
    58621 atattgcaca atagtgcaaa ataaagtgac tatctcttct tatggttaag gatacgcaaa
    58681 agtcgcaata tatgataaaa tagttacgaa agaaacattt ataatttcgt aagaaagaag
    58741 gagaccccgc atgactgaaa caaaaagccc ttattttgga catttaacag acagaatggc
    58801 tcactatcgt gaagctgtgt tagacaagaa accttatatt gatgctgagc gtgctatttt
    58861 agccactgaa gcctatcaaa aacaccaaaa taagccagca aacctcaaac gcgcttacat
    58921 gcttcaaact attttggaaa acatgaccat ctatattgag gatgaaagcc tcattgctgg
    58981 taaccaagcc tcttcaaaca aggatgcacc gattttccca gaatacactc tggaatttgt
    59041 ccttaacgaa cttgatcttt ttgaaaaacg agatggggat gtcttctaca ttaccgaaga
    59101 aaccaagcaa cagctccgag acattgcccc attctgggaa aacaataacc tgcgtgctcg
    59161 ctgcggtgtc ttgctaccag aagaagtgca agtgtacatg gaaacaggtt tctttggcat
    59221 ggaaggcaag atgaactctg gggatgccca tttagcggtt aattaccaaa aactcttgga
    59281 acacggcttg aagggatttg aagaacgggc acgagctgcc aaagctgcgc ttgatctgac
    59341 cattcctgaa aacattgaca aataccattt ttacgactct gtttttattg tcattgatgc
    59401 agtcaaaact tatgccaaac gctatgccaa gttggctaga gaattagcaa aaacggctaa
    59461 accagaacgt caagcagaat tgttagacat tgcgcgcatt tgtgacaaag tgccttacga
    59521 accagcgaaa acctttgcag aagctgtgca atctgtctgg ttcattcagt gtatcttgca
    59581 aattgaatca aacgggcatt ccctatctta tggccgcttt gaccagtaca tgtatcctta
    59641 tgtcaaagct gatttggagg ctggccgtga aacagaagac acaatcgttg agcgtttgac
    59701 caacctctgg attaagacct tgaccattaa taaagtacgg agccaagccc acaccttctc
    59761 atcagcaggg agtccacttt accaaaacgt gacgatcggc ggtcaaacac gagataaaaa
    59821 agacgcggtc aacccactgt cttaccttgt cctaaggagt gtggctcaaa ccaaattgcc
    59881 acaacctaac ttgactgttc gttaccacaa aggcctagac aataccttta tgaacgagtg
    59941 tatcgaggtc atgaaacttg gttttggtat gccagccatg aacaacgatg aaatcatcat
    60001 tccatctttc atcaaaaaag gtgtctcaga agaagacgcc tatgactact cagccattgg
    60061 ctgtgtggaa acagcagttc caggaaaatg gggctaccgt tgcacgggga tgagttacat
    60121 caacttccct aaaatcttgc tgattaccat gaacgacggg attgacccag catcaggcaa
    60181 gcgctttgca aaaggacacg gtcatttcaa agacatgacc tcttatgaag aattaaaagc
    60241 agcatgggat gccaccctgc gcgaaattac ccgcatgagc gtcattgttg aaaatgccat
    60301 tgacctgggt cttgaacgtg aagtaccaga tattctttgc tcagccttga cagatgattg
    60361 tatcggtcgt ggcaagacct taaaagaagg cggagctgtt tacgactata tctcaggcct
    60421 tcaagttggt attgccaacc tatcagactc cctagcagcg ctgaaaaaat tagtgtttga
    60481 agaaggtcgc ttgacccccg aggaactctg gcaggccctt gaaagtgact ttgctggaga
    60541 acgcggagaa gagatccgac aaatgctcat caatgacgca ccaaaatatg gtaatgatga
    60601 tgactacgca gatagtttag ttgtcgaagc ttacgacacc tacattgatg aaattgccaa
    60661 atacccaaat acccgttatg gacgtggccc aatcggaggt atccgctatt ctgggacatc
    60721 atcaatctca gccaatgtcg gacaaggaaa agggaccttg gcgacaccag acggtcgcca
    60781 tgcaggcaca ccactagcag aaggctgttc accagaacac agcatggaca aaaaaggacc
    60841 tacttcagta ttgaaatctg ttgctaaatt accaacagat gagattgtcg gaggagtact
    60901 actcaaccaa aaagttaacc cacaaaccct ggccaaagaa gaagacaaac tgaaattaat
    60961 ggccttactt cgtaccttct ttaatcgcct acacggttat catatccagt acaatgtcgt
    61021 gtcacgtgaa accttgattg atgcccaaaa acatcctgaa aagcaccgcg acctcattgt
    61081 ccgtgttgcc ggctactcag ctttcttcaa tgtgctctca aaagcaaccc aagatgacat
    61141 tattgaacgt acggaacaca cgctttagaa agaagaatac ttatggaata catgttagac
    61201 actctagatt tagaagctat taaaaaatgg catcacattt tgcctctcgc aggtgtgacc
    61261 tcaaaccctt ctattgccaa aaaagaaggt gacattgatt tctttgaacg gattcgagaa
    61321 gttcgtgcca ttatcggtga caaggcttct attcatgttc aagtgatcgc ccaaggttac
    61381 gaaggcatct taaaagatgc tgctgaaatc cgcaggcaat gtggagatag tgtgtatgtc
    61441 aaagtacctg taaccacaga gggccttgca gccattaaaa ccttgaaagc cgaaggctat
    61501 catatcacag caaccgctat ttatacgacc ttccaaggac tattagccat tgaagctggc
    61561 gctgattatt tggctcctta ctataaccgt atggaaaatc tcaacattga tccagaagct
    61621 gtcataggac aattagcaga agctattaac cgcgagaatg ctgatagtaa gattttggca
    61681 gcaagcttta aaaatgtggc tcaggtcaat aaatcctttg ctctgggagc acaagccatc
    61741 actgctggcc cagatgtgtt tgaagcagga tttgccatgc catctattca aaaagcggtt
    61801 gacgattttg gcaaggattg ggaagccatt catcaccgca agagcattta agaaatagca
    61861 tcagtagtaa tcacatcatt aggaatcaca gataaaggag ttcaacgatg aaagtatttg
    61921 caagtccatc tcgttacatt caaggtaaaa atgccttgtt taccaatgct aaaaccctaa
    61981 aacaactagg ggatagcccc attttactgt gtgatgacgt ggtgtatggc atcgtcggag
    62041 aaagatttga aagctatttg atagataatg gcatgactcc tgttcacgta gcctttaatg
    62101 gcgaagcctc agataatgaa atcagccgcg tggttgccat tgccaaggaa aatggcaatg
    62161 atgttattat tggacttggt ggtggaaaaa ccattgacag tgctaaggct atcgctgact
    62221 tacttgctgt tccggtgatt attgccccaa ccattgcttc aacagatgcc ccaacctcag
    62281 ccttatcggt tatttatacc gatgaaggag cctttgaaaa atacattttc tattcaaaaa
    62341 atccagatct tgttttggtt gacacacaag taatctgtca ggcaccaaaa cgcttattgg
    62401 cgtctgggat tgcagatggg ttagcaacat gggtagaggc gcgtgctgtt atgcaaaaaa
    62461 atggagacac catggcaggt ggcaatcaaa ccttggcagg agttgccatt gccaaagcct
    62521 gtgagcagac cttgtttgca gatggcctaa aagcgatggc tagctgtgac agacaagtcg
    62581 tgaccccggc cttggaaaat gtcattgaag ccaatacact tcttagtggg cttggttttg
    62641 aaagtgcggg tctggctgct gcacatgcca ttcacaatgg ctttacagca ttgacaggtg
    62701 ctattcatca ccttacccat ggtgaaaaag tcgcctatgg cacgttgacc caactcttct
    62761 tggagaatcg ttcgcgcgaa gaaatagacc gctacatcga cttttaccaa gccattggca
    62821 tgccaacaac cctcaaagaa atgcatttag acacggctac tcaagaggat ttcttaaaaa
    62881 ttggccgtca agcaaccatg gcaggcgaaa ccatccatca gatgccattt gttatcagcc
    62941 cagaagatgt agcagcggct ttggttgctg ttgatgccta tgttacgagt cgataggcta
    63001 accaaaaaga gatttcttat ttgccagata acctcaaaaa aacaagtcta gggagtcact
    63061 tcctagactt gttttgctta ctgttggttg gtaatagcac ttttagcggg gtcattgtgg
    63121 gcaatacgac tggcagctgc agcagcaatg gcgctaacaa tatcatctaa aaaggtatgg
    63181 caggagttgc catctttatg gttgagttta tcaacaattc ccggttttgt cttgtccaga
    63241 tacccataat tggtaaaacc gatagaccca tagaggttaa caatggataa ggccaggatt
    63301 tcatcaatcc catacagccc ttggtcggtt ttcaagatac taaggagtgg ctcaaacagc
    63361 tggttggctt cagccaattt atccaattct accccagtga taatagcatt ttgcacttct
    63421 cgttttgcaa gcaccgcctc aacgctctct aaacattctg ccatggtcaa attgggaata
    63481 taatcattct gcaaaaaaag caccagctct gcaatagctt ctaaagaaac ccctcgctca
    63541 gccagtaatt gataagacac ttctcgtaag tgatggtcag ttgacatgtg agacctcctt
    63601 tttttcttta ttgtaacata aaagatttta agaaacctct acaacagcta aagaggggat
    63661 agttcttttt taagaggtgt tgactactga gatctcctac ttggtaaaag tcaaagaaac
    63721 gatagtaaag taaccatctt acctaggcct aaatacaatc accaccccta ggtgacacac
    63781 agcacctatt tcaaaaatga tattagtatg gcaaaacaaa aagacaacgc cttctttttt
    63841 ctccttacta tctcgtttaa ttttcatatt ttttaaaaaa actattgata aactagttaa
    63901 gtaagcgtat actatggtta gtgagcgaaa ttagaaaaga ggacaagcat atgaatctac
    63961 ttggatcaag acgggttttt tctaaaaaat gtcggctagt gaaattttca atggtagctc
    64021 ttgtatcagc cacaatggcc gtaacaacag tcacacttga aaatactgca ctggcacgac
    64081 aaacacaggt ctcaaatgat gttgttctaa atgatggcgc aagcaagtac ctaaacgaag
    64141 cattagcttg gacatttaat gacagtccca actattacaa aaccttaggt actagtcaga
    64201 ttactccagc actctttcct aaagcaggag atattctcta tagcaaatta gatgagttag
    64261 gaaggacgcg tactgctaga ggtacattga cttatgccaa tgttgaaggt agctacggtg
    64321 ttagacaatc tttcggtaaa aatcaaaacc ccgcaggatg gactggaaac cctaatcatg
    64381 tcaaatataa aattgaatgg ttaaatggtc tgtcttatgt cggagatttc tggaatagaa
    64441 gtcatctcat tgcagatagt ctcggtggag atgcacttag agtcaatgcc gttacaggga
    64501 ctcgtaccca aaatgtagga ggtcgtgacc aaaaaggcgg catgcgctat accgaacaaa
    64561 gagctcaaga atggttagaa gcaaatcgtg atggctatct ttattatgaa gctgctccaa
    64621 tctataacgc agacgagttg attccaagag ctgtcgtggt atcaatgcaa tcttctgata
    64681 atactatcaa cgagaaagta ttagtttaca atacagctaa tggctacacc attaattacc
    64741 ataacggtac acctactcag aaataatacc aaaaggctag acctctgctc actaggccta
    64801 gctttttaca tcaaaaaaag caatgactat agaaagtaaa aatactagaa aaagcaatga
    64861 ttgccgtcat tgctttttat gatttgtcaa aaagtaaaaa gcaaattgaa aaaatcgccc
    64921 tggagctgtt gagataaact acaccattta ttaagatacc aaatcaaaaa gctaacacca
    64981 taagagcgtt agctttttaa agagcctcag gacagtttat gtttaatggc ttctaggtag
    65041 gtttgaaaca tatgatggat cgttttgcaa ttgagtaatt ggaagatctc caagatctgc
    65101 acacactttt gctcagcccc ctctttacca tttatgaggc caataatgcc atcaaaaaaa
    65161 gacacacaac accgttcata taagcaatca tcatttagct gataatcttc aatttttgcc
    65221 aaaatctcag aagctttatc atactcttgt cgctgaataa acaaaatcaa catattgaca
    65281 aacatccgaa tcgattcatt cccataatac cttagggtat tgtatttatc gaggttcaaa
    65341 ataacttttg aaaacaccat ctcaataaaa caagactcaa aaataaacat acaattatta
    65401 aaaagcacag tctcatagtg actccaagtt tcaatattaa taagatagtt tgacaaataa
    65461 gtccgctctg tcagacagtc tttctcagta agagttgcta ataacacctt gaccaaggca
    65521 aaaaggttct tttcctttgt tgacttacta tctttataag aatcaaggat atgatttaaa
    65581 ccttctatgt ttcggcactc aaaataatgt tttgccgtat ccatatcaat aaattcttta
    65641 tattgtttaa agttattact aataaagaga aactcatcaa cattgacatt caagttgtct
    65701 aagatataaa gtaacttttt cgaagaaatg tcaagattat ttttaataaa acgataatag
    65761 gtttgcctag tgagataatc accacaaact tgtttaatcg aaatgttttt tgaatgccta
    65821 atgaattcaa cggtttcacc aatttccata tgtcaagcct tcctagttga tgtcaaaaat
    65881 acgttacgca tgtacctaat acgtaacaag ttgaatgttt cggatgatag tcgcttatga
    65941 taggtgcata aggtcaatag ccagatgcga tagttttatc aactgtcata tgttaaacct
    66001 ttctaatcta atagatgtta aaaatacgtt acgtgtgtac ctaatacgta acaaaataat
    66061 gggttagcaa aataagcagc tatgatatag ccataaggtt aaaaggaggc gcctactatg
    66121 tggttattgt tactattttt gtagttcctt ttgcaaaatg gtagtagata aaaatgagaa
    66181 gtcaataaaa gcattgacaa acaaaagaat cattttgttt atattatcag tatttttaag
    66241 tttcttgtca actgaaatga gcatctacta gccacaatag taactaaaag gctaattgtc
    66301 agtaaaaatg agataaatca gccaggaaaa agcctacgag tcaactaatg gacaacccaa
    66361 aaaaagacaa aggactttca cttggtgttg tggaccctat cacgatcctt atcacagaat
    66421 cagttattaa caaaatgaga acggtcccat atcatctaaa aaaactgtca agcacaacct
    66481 attgtttgct agctgatctt gcctatcagt ctgcctagta gatacgacag aagataagag
    66541 atcaaccaaa agatgataag tacaacgact catagcgtct tttgaccaaa accaattagg
    66601 ctcacatgag atgagaataa ttgggttggg ttgtcagtgt caactaaccg tgttattgtc
    66661 tattaccatt catggtatca gcgacatcgt atgataacca tacgattcag ctaagtaagg
    66721 aggtgtgtcc aatgtaccgt taaaagcaaa tgcagtagat taacttattt tgaaagaggt
    66781 ataaaaaaaa tgaataaaaa gaaattaggt atcagattat taagtctttt agcattaggt
    66841 ggatttgttc ttgctaaccc agtatttgcc gatcaaaact ttgctcgtaa cgaaaaagaa
    66901 gcaaaagata gcgctatcac atttatccaa aaatcagcag ctatcaaagc aggtgcacga
    66961 agcgcagaag atattaagct tgacaaagtt aacttaggtg gagaactttc tggctctaat
    67021 atgtatgttt acaatatttc tactggagga tttgttatcg tttcaggaga taaacgttct
    67081 ccagaaattc taggatactc taccagcgga tcatttgacg ttaacggtaa agaaaacatt
    67141 gcttccttca tggaaagtta tgtcgaacaa atcaaagaaa acaaaaaatt agacactact
    67201 tatgctggta ccgctgagat taaacaacca gttgttaaat ctctccttga ttcaaaaggc
    67261 attcattaca atcaaggtaa cccttacaac ctattgacac ctgttattga aaaagtaaaa
    67321 ccaggtgaac aatcttttgt aggtcaacat gcagctacag gatgtgttgc tactgcaact
    67381 gctcaaatta tgaaatatca taattaccct aacaaagggt tgaaagacta cacttacaca
    67441 ctaagctcaa ataacccata tttcaatcat cctaagaact tgtttgcagc tatctctact
    67501 agacaataca actggaacaa catcttacct acttatagcg gaagagaatc taacgttcaa
    67561 aaaatggcga tttcagaatt gatggctgat gttggtattt cagtagacat ggattatggt
    67621 ccatctagtg gttctgcagg tagctctcgt gttcaaagag ccttgaaaga aaactttggc
    67681 tacaaccaat ctgttcacca aatcaaccgt agcgacttta gcaaacaaga ttgggaagca
    67741 caaattgaca aagaattatc tcaaaaccaa ccagtatact accaaggtgt cggtaaagta
    67801 ggcggacatg cctttgttat cgatggtgct gacggacgta acttctacca tgttaactgg
    67861 ggttggggtg gagtctctga cggcttcttc cgtcttgacg cactaaaccc ttcagctctt
    67921 ggtactggtg gcggcgcagg cggcttcaac ggttaccaaa gtgctgttgt aggcatcaaa
    67981 ccttagtatg gaaatgcatt tcgttagaac agaacctgag gcacgccgca tagctgaaac
    68041 cttttgtgcc gaaaacacac aaacaaaaat ccctatgcgc gtgcagcagt taagctatcc
    68101 atcagacaca gatcactcag gtggtgagct atacatctat gctttgtctc ctgctggatt
    68161 tatcatcgta tcaggagaca ccagagcgca caccatttta ggctattctt ttgataataa
    68221 cctagacctc aaccatgata atgtcaggag tatgatagaa gcttaccaaa cacaaatcaa
    68281 ctctttggat tgatcggtca aagtagcttt tgcccccctc accactcgtt taagacgacc
    68341 gtgtttctaa aataccacta ccttttaagt ttcacgccgg cctaagcgag tgtttgtctc
    68401 atggagcaga ctgtttccat cgaaaagtca cccattgata aaggaggtca tcaacgccta
    68461 ctaatgatga cttccctaag atgccaaggt aaaggactga gttctgtaga gatgggactc
    68521 agtcctttta cgatttttga gagttattct agccataccg tggcaagaaa acaacactta
    68581 aaaatagcca acgtcagttt ctgttcatat atgactacag ccaaacacca caacctaacc
    68641 tatcctaaac acaatggctt tctaacgaac agtcacaacg agcagcaaca ccaaaaagca
    68701 agattaagct acgtttaaga ctaatgatat aagataacag taattattaa tgagaaaaga
    68761 ggctcaggac atgaaacaaa tgaataaact cattacagga gtggtaacgc tggcgacagt
    68821 cgtgacctta tcagcttgtc aatcatcaca caacaacacc aaactcgtct cgatgaaagg
    68881 agacaccatc acagtcagtg acttctacaa tgagaccaaa aacacagaac tcgcacaaaa
    68941 agccatgtta agcttggtga ttagccgcgt ttttgagaca caatatgcca acaaagtctc
    69001 tgacaaagag gttgaaaaag cctataaaca aaccgcagac caatacggta catcctttaa
    69061 gacagtccta gcacaatcag gcttaacgcc agaaacctat aaaaaacaaa ttcgcctcac
    69121 aaaattagtc gaatatgccg tcaaagaaca agccaaaaac gaaaccatct caaaaaaaga
    69181 ctaccgtcag gcctatgacg cttatacccc aaccatgacc gcagaaatca tgcagtttga
    69241 aaaagaagag gaagccaaag cagcccttga agccgtcaaa gctgaagggg cagactttgc
    69301 agctattgcc aaagaaaaaa ccattgcagc cgataaaaaa acaacctaca cgtttgactc
    69361 aggcgaaaca accctaccag cagaagtagt tagagctgca tcaggcctca aagaagggaa
    69421 cagatcagaa atcatcacag cgcttgatcc agccacctca aaacgtacct accatatcat
    69481 caaagtcacc aaaaaagcaa ctaaaaaagc agactggaaa gcgtaccaaa aacgcttgaa
    69541 agacatcatc gtgactggca aattaaaaga ccctgacttc caaaacaaag tcatcgctaa
    69601 agctcttgat aaagcaaatg tcaaaatcaa agacaaagca tttgccaata tcttagccca
    69661 gtttgcaaaa cctaaccaaa aacaacctgc ccaaaaatag aagattgcca gtttatttcc
    69721 ctaaggttgc ttaaaaagac agccctagcc atcactcccc ttttcaaaat accgataatg
    69781 gaaacgtgtc ctatactgat ggtctagggc aatgtcataa agctaaagac tctatcccaa
    69841 taaggataga gtctttaatg ttttaaaacc agtcagcaaa aaaattcacg ctaagcctca
    69901 ttctaggctt agcgtgaatg gtatcagtga tagtccgtta aactagctga ttgggaatca
    69961 gaaactctcc ttacccaatc tgactatacc cccagtacca gaggtgtctc atcgcagaag
    70021 tagcaatcag ataatcgtct gataagctct tgtcctcaag caactgatga gtatcgtcgc
    70081 acgggccatg agctgttggt ggctgatagc cagtaggctc atcagccaaa acttttttgg
    70141 agtaacgctt tggtctcaga cggcggcaga gggttgaaag aggggtgaga aaaaaacgat
    70201 gggtcatctt ggcctccttg tctaatgata gtcaccttaa cagacaaaag tgtcaataat
    70261 gtcattttaa ggagaaaaag attaaaaatc aaggtcacaa aatttcattt gttaaaaaaa
    70321 cgcgacccta acaaaggacc taaatccccc tcgcacttga gcttctcctt gcgcagctat
    70381 cttttgcact cagttgcata caagctaatg atagcgatat cattattgtc ctataggcta
    70441 tcgcgacaac cccttttttc gcctcaacga ggctgacgca gctgtcatga cagaaaaaag
    70501 acctctgcct atctaaggga ccattaattt ttctctcacc aaaaaactga ttttagaaac
    70561 gaaaaagcat ggtgtataat aagattcgga acaattatga cataataatg aaagtaaggt
    70621 taacgaaaca ttgacaaatt gtaagtataa acttagaaag ttatctgtag ggctcgtctc
    70681 cgtcggaacg atgctgatag ccccgacagt tttaggacag gaggttaata ctggtgctac
    70741 tagtacggag agcagtacta ctagtaccga tacggctacg acaagtggga cagctaccac
    70801 tactaccggt acgagtggaa cagctgccag cggagctagt agtgaagcaa ccgtagctac
    70861 tgcccctact accaatggag gaagtcagtc tactccagca gcagctgaaa cgactctaca
    70921 acctcaagca cagacagctg tggcagcaac gtcggcacca tcgacctctt ctagtaacgc
    70981 gaaaactgaa gagcaaactc ctaaggcagc aagcactaca tcaccttcaa ctccggcaat
    71041 agccactagt gatggcaacc aattaactgg tactgaagct gaaactccaa tgatggaagt
    71101 ggaacagtat acagttgata ataaagaaac agagcttaat gttaaagacg gtacggtact
    71161 cagccaaaaa aacgggggga gaagtgttag tcaaaataca aaacttatta gaaaccgtga
    71221 tggcgagcaa cgtggtattt ttgatatcaa gcgtgaagta aaaacaaacg cagatggcac
    71281 tgtcgatgtt acggttaccg taacgcctaa agaaattgac aaaggtgccg atgttatggc
    71341 ccttttagat gtctctcaaa agatgacaga tgctgatttt aaaaatgcta aggataagat
    71401 caagaaatta gtcacaactt taacgagtaa atcaaatagt gatgagcata aacataattc
    71461 tcgaaattcg gttcgtctga tgacctttta ccgtaaggtt aacgatccga ttgagctcaa
    71521 cgcagataat gtagatacta aactagatga ggtttgggaa aaagccaaaa aagattggga
    71581 ctggggcgtt gacctgcaag gagccatcca caaagctcga gagattttta ataaggaaaa
    71641 agaaaaaaac tctggtaaac gccagcatat cgtcttgttc tctcaaggtg agtcgacttt
    71701 tagttatgac atcaacgaca aagataaaaa tgatactgtc aagaaaaata gaatagctgg
    71761 aaaagttacg acctctaatc cactatttcc ctggctacct atatttaatc atacaaatca
    71821 aaaagcagaa gttattgatg atgtagacaa attactggat ttagctgaaa aaatgggaat
    71881 atcactgccc aatggattaa gagcaggagt gaaggctatt ggggcaagta gtagtctcct
    71941 tagtaccttc acaggatctg gattgacaga gtacctcgct ttgaatgaat atcgctcaga
    72001 tatactaaaa gaaaaacagt tcgattatac caagcgtgta ggcgagggct accactacca
    72061 cagttattca aagcgaactc atggagataa gatgcccttt gagaacgaaa taagacaagt
    72121 tttagagcga tttttaccga aaatcgaaaa taaagaatgg gctaaaaagt ttatagaaat
    72181 ttttggatta caagaacaaa aagtaaatca aattggggta gatgtaatta tgaaagtaat
    72241 taacagcatc ttctacagtc gccaatacta ctactataat cacaacctgt cagcgatagc
    72301 tgaagctaaa atggctcagg aagaaggtat caccttctac tccgttgatg ttactgattt
    72361 aaaacctaaa agagcgaagc gacaaacagt agtacgtcag aaaaccacga aaaaagaatc
    72421 cgaagaagac cgtaataaca aatttgatgg gtatcttaaa aagatgtctg aaggtgatac
    72481 tttcttggat aatgttgaaa agaaagataa gtttaaagat attttagacg aactgaagtt
    72541 tacagataaa tttacaaatg aagttactgt tgaggaaaag tcattagata aggtttcaac
    72601 tgatgctagt tcccaggaaa atggtagcca aaaagttgaa cataaaaagg caagtaatgg
    72661 ttcactattt atgagccctt ctcaagaaag cctcacttgg actatttcca aagagcagct
    72721 caaagaagcc tttgagaaaa atagctctct cacttttaaa tacaaattac gggtcaataa
    72781 agacaaacta ttaaataaag ataagaagag aataaaacac tctgcaccta cagaaaatga
    72841 aaactctgta actaaaaaaa tcatttcaaa tattactacc tacaaaatta atggtcaaga
    72901 agttaagggt aacaacctta gtgatgttag tctgacatac agtaaattca aggttcctgt
    72961 accacagatt gatgggcatg ttattgagcc acaagcacct aaattacctg agttacctcc
    73021 tgttattgag catggacctg ttcttgatta caaagaagag tcaatatacc gattaccact
    73081 tgaacatggc agcaatgcac cagacacaca agtgacaatt gaagaagaca cagttcctca
    73141 acgcccagat atccttgtag gcggtcagag tggaccggtt gacatcaccg aagataccca
    73201 accaggtatg tcaggctcaa atgacgcgac agttgtcgag gaagacacag cacctaaacg
    73261 tccagatgtc cttgttggtg gtcaaagtga tccaatcgat atcaccgaag atacccaacc
    73321 aagtgtgtca ggctcaaatg acgcgacagt tgtcgaggaa gacacagcac ctaaacgtcc
    73381 agatatcctt gttggcggtc aaagtgatcc aatcgatatc accgaagata ctcaaccagg
    73441 tatgtcaggc tcaaatgacg ctactgttat cgaagaagat acgaaaccaa aacgcttctt
    73501 ccactttgat aacgagccac aagcaccaga aaaacctaaa gagcaaccat ctctcagctt
    73561 accacaagct ccagtctata aggcagctca tcacttgcct gcatctggag acaaacgtga
    73621 agcatccttt acaattgttg ctctaacaat tattggagct gcaggtttgc tcagcaaaaa
    73681 acgtcgcgac accgaagaaa actaaccctc gttagtctag cgaccctaag cctttggctt
    73741 taaaaatttc tcattatccc cctcaaacac cggttcctca ctgagatggc gcttaaaaaa
    73801 agccgctagt ctcaaatcag gtatccccta cggttgaggg ggattaatgg gtatcacaac
    73861 aagtaaaaag gtataatgat gaaatatgac taaaaaattt attaaatcag cagtgattct
    73921 aggcttagca agcataacca tcagcatgac gcaacccgtt gaagccattg caaataactc
    73981 aaaatatcaa gcacaatacg aacgtgtcaa aaaagaacta gacgcattaa aagcaacaag
    74041 tccaaaatta ggagaacgtt ccctttattt tagattggtg aatagatttc taggttggtt
    74101 tggcgtagtc tgggacccac tcgcaatcaa agaaaccgat cacctgttgg acctcatcgg
    74161 acaagtcaat tacttggtga gtaacaccga gtttcaagcc cctgagtacc aagaggctaa
    74221 aaacaaacta gatttagctg tagcaggcta tgacctctac ctatctagag aaaaaggacg
    74281 tggtgatgct cctgattacc aagtgaccca gctaacgcta gatcagctca aaaccatcaa
    74341 aacgaagata caagaggccc tgaaaacatt tgcacaagag gtcaaaacaa tccaacaaaa
    74401 aaacccagac ctatttcccc atgcttatgt tttaaacgct aagagcaaag atatcacaga
    74461 taaagcgcaa ccctttttag tgaatggtta ctacgatgtc ttttataagc agtttttatt
    74521 cactaataca aaggacgggt acaactataa taaagaagca gacaacctgg cctcgtatca
    74581 aaagctgatt aaagagctat taacattgaa agctgagatc gatcagttaa caacagacaa
    74641 gcctaaaaac gatcgtttag agacgttaat gtgggaatca aagttcacct tatctgactt
    74701 tcggagaact tcacgcctta gcgcctacta tacacaagaa gattatgtca aaaaggtggt
    74761 cctatctgaa gaagctccca acttgagaac agcaaaagaa aaggtcaaga ccttaaaagg
    74821 gatcttgtat gattactatg ttgatattaa agatccagaa aaagctaaaa agtatcgtgt
    74881 cgaggacgag accttgccgt ctcaacctga ggtccctgct aaacctgaag ctcctgttcc
    74941 tggtcaaaaa ccagcagaag atgagggatc gtcacaagct acggaaccaa ctaacccgtc
    75001 aaaagagaat tcttcaacgg acgcatctca gggatctcac gatagtgaaa acccagcgac
    75061 agacagtcct tctcaacctc aggcaccaga ccaaggcaat caccaaagcc aagtgcctaa
    75121 cgacaagcct caaacggaca agacggacac tcctaacgtc ccagcccctc cacaggacac
    75181 tcctaacgcc ccagccatcc cacaggacac cccaaaagtg cctgaggctg gtggtcagag
    75241 tggccccgct gggaacgctg aggagaaagc tcctgactct ggacctaaag agtctggaca
    75301 aagctcgtct aaagagtccc catccgttgg cgaagacacg acccctaatc agccagacgt
    75361 ccttgtaggt ggtcaaagtg agccaattga tatcaccgaa gacacaatca ctgacgctcc
    75421 tccgacagta tctgggcaca acgcatcaac acagccccaa tctgtggtcg aagacacggc
    75481 acctcagcgc ccagatgtcc ttgtaggtgg tcaaagcgag ccaatcgata tcacccaaga
    75541 tacccaaccg ggcatgtcag gctcaaatga cgctaccgtt atcaatgaag atacaaaacc
    75601 aaaacgcgtc ttccactttg ataacaaaga gccacaagca tcagaaaaag cggcagagca
    75661 aaaacttgct cctcatgata gccacacaac ccctcaaact tcagatgata cagcagcccc
    75721 tcacttgcct gcatctggag acaagcctga aaaagtgttt gcacttgctg ccttgacaat
    75781 ggtcgcagct gcagggctac tcagcaaaaa acgtcgcaac accgacaaaa actagtcgct
    75841 gttaggcaca acgcatcact aaggccagtg caaatgcact ggccttagtt aggtttttat
    75901 caaattttat gacaattgct agcgtttcag tgtaaaataa aggtaataac cagcaaagga
    75961 gcaacccatg acaaagcaag atcagttaat cgttgaaaaa atggaacaaa cctatgaggc
    76021 ctttagccca aagctagcaa atctcataga agccctagat gcctttaaag agcattatga
    76081 ggaatatgcc acacttagaa atttttacag tagtgacgaa tggtttcggc ttgcaaacca
    76141 accttgggat gatatctcgt gcggtgtcct atctgaagac ctcctctttg atatgatcgg
    76201 tgaccataac caactactag ctgatatctt agacttggcc cctatcatgt acaagcatat
    76261 gtaaccatcg ctaacgtcac agatactacg atgacaggac aaaaaaagct agccaatctc
    76321 aaaaaaacag ataaaaaaca gataatcgtt agaaaaacag tagatgcgtc tgttaaacta
    76381 aaggtatcaa aacaaaagga gcatttcatc atgaaattca aaaaagtatt agtcattcct
    76441 gcattagcat tagcagcaac atgcttttta acagcttgtg gcacaaaaaa agattctaaa
    76501 aaagaagaag ttaaagaaat caaaatgtct gacatcaaag acgacgcagt tagcaaaaaa
    76561 acaaaagtgg ttgatggcga agaagttaca gaatacacca caaaagatgg aaacgtgatt
    76621 cagattcctg caggaaacga agaaggcatg gaatcaaaag atgctggtgg atcaggcgct
    76681 cctgctaaaa actaagggtt acaacaaaga gcataaggtg actcgcaaac gttacgcatg
    76741 acatgaggca gtctgcctaa gatggtaact cacttatcat aatgcctaaa tagccaaaca
    76801 cactaactcg caaatgtaca aaatcatata cccgtgctta tgtgagcgaa cggttatatg
    76861 atttttgttt tccaaaaaca agaaaagaac gctaaaatag ccagtttgtc gtgtttcaag
    76921 ctaccaaaaa ggaagtgcta aaatgaaaaa aagatccatt atacctgtca tcttactgtt
    76981 ggtcatcgga ttaatcgttg gtgttaagcg tcatcatgac tagtaggtct tgctagtgac
    77041 cgttcaaaag ggataacgtt ggtatggtat aaccataaaa atcgtataaa aagaaaaaat
    77101 agctattgag gagaaagtat gtttcagtta agaaaaaaaa tgacgcgcaa acaattagcc
    77161 ttgttgagtg ctggagtgtt gacctgtgtg gttggtggta cctacttgat aatgaaccat
    77221 caacaacaag aaattgtctc tagtgtcaac aaagtaaaag ccttaaccat aaaagaagcc
    77281 atggaacaag gaaaagatat cagcttgacc ttagctggcg aagtaacagc taacaacagc
    77341 agcaaagtca aaatcgactc aagtaaagga gaagtcaaag atgtctttgt caaaaaaggc
    77401 gatgttgtca aagtaggaca acccttgttt agctatgaaa cgtcacaacg gttaacggct
    77461 caaagttcag aatttgatgt tcaaaccaaa gccaatcaac tccaagttgc taaaaccaat
    77521 gcagcattga agtgggaaac ctacaatcgc aaggtcaatg aaatcaatac cctaaaatct
    77581 cgctacaaca ctgcaccaga tgagagctta ctagagcaaa ttcgcagcgc agaagacagt
    77641 gtatcccaag cactaagcga tgccaaaaca gcagatagcg atgtcaaaac cgctcaaatc
    77701 gaactcgata aagctaatgc tactgccaca acggaaaaag gtaaactaga gtatgacacc
    77761 gttaagtcag acaccgcagg aaccattgtt agcctaaata ctgatttgcc aaatcaatca
    77821 aaatccaaaa aagaaaatga aacttttatg gaaattatcg acaaatcaaa aatgttagtc
    77881 aaaggtaaca tcagtgaatt tgaccgtgac aagttaaaaa tcggtcaaaa agtcgaagtg
    77941 attgaccgca aagacaactc taaaaaatgg actggaaaag taacccaagt tggcaacctc
    78001 aaagcagagg aaaaaggcca aggtcaaggc caaggtggca atgaccaaca agacaatcca
    78061 aaccaagcaa aattccctta tgttatcgaa cttgaccaat cagacaagca gccactcatt
    78121 ggctcacaca cctatgttaa tgtgctcaac aatgttccag aagctggcaa gatcgtatta
    78181 aaagaaacct ttacaatggc agaaaatgga aaaacctatg tgtggaaagt tgataaaaac
    78241 aaggtcaaaa aacaagaaat caagactaag ccattctcaa aaggttatgt tgaggtgaca
    78301 agtggcttga ctatgcaaga taagattgct cagccgcttc ctggcatgaa agacggtatg
    78361 gaggtaggaa gtattgttaa accttaaaga tattcgaaaa agctatcatc ttggaactga
    78421 agaatttgcg attttaaaag gaatcgattt agaagttaac gagggtgact ttttagccat
    78481 catgggacca tcaggttcgg gaaagtcaac attgatgaat atcattgggt gtttagataa
    78541 gcctggctct ggctcatatg ccattgaagg cagagacgtg tcatccttat ctgataatga
    78601 acttgctgat ttgcgtaatc aaaaaatcgg ctttgttttt caaaatttta acctgatgcc
    78661 caagctaaca gcttgtcaaa atgtcgaatt gcccttgact tatatgaatg ttcctaaaaa
    78721 agagcgtcgc aaacgagccc tagagatgtt aaagctagta ggactagaag aacgtagtga
    78781 atttaaaccg atggagctat ctggtgggca aaaacagcgt gtagcgattg caagagcttt
    78841 agtcactaac ccgagtttta tccttggtga tgagccaaca ggtgcactag acacaaaaac
    78901 cagcgtccaa atcatggacc tatttaaaca attcaatgat aacggcaaaa cgattattat
    78961 catcacacac gagcctgaag tagctgccct atgcaaaaag acggtgatcc taagagatgg
    79021 taatatagaa cattccgata tagagtaaag ggggaaaata atggaagata ttattgcagc
    79081 tttaagctct atattatcac acaagatgcg gtcaattttg acaatgctag ggattattat
    79141 cggtattggt gccattatcg caatcttttc aatcatcgaa ggtaataccg aaaataccaa
    79201 aagacagttg attggtggca gcaataacac tattaacatt gtgtttaaca aaaaaagcag
    79261 tattgaccct aaatttccag acaagtcaaa tgctaaaaaa ccagactatc ttccttttat
    79321 ggctgaagaa gaacttagca aaatacagca agtcaaaggc gtcaaaaacg ccctgatctc
    79381 atatggtatt gatgacaaag tctaccatct aggccaaaaa tcatctgcaa agatttctgc
    79441 catcacaaaa aacgtagctg aagtgagacg catgacattt attaaaggca gtgacttttc
    79501 agacaaagac tttattgacc aaaaacaggt gatttacctt gaaaaaagct tgtatgagtc
    79561 actatttcca aaagacgatg gccttggaaa atttgtcgaa gtgatgggaa atcccttcag
    79621 ggtcattggg gtgtttgaat caaaagaaca aagtggcctc acaagtggga ctgagaaaat
    79681 tgcttatatc ccgctacatc agtggtataa tattaatggt gtagtggatg cgacacctga
    79741 gatcacgatc cagacctatc gcgcagatga cctcaaacct gtagcaaagc gtgttagtga
    79801 tatgctcaat caaacgatcc ctaaatcaga ttatatgttt ggtgtcatga accttaaaga
    79861 atttgaacgc caactagaca acctaaacaa atctaatttt gtgttattag ctggtattgc
    79921 tagcatctct cttattgtag gtggtattgg tgtgatgaac attatgctag tatcagttac
    79981 cgaaagaacg agagaaattg ggatcaaaaa agcgcttggc gctagacgta agcttatttt
    80041 aaaacaattt ttaattgaag cggtcattct aaccttgcta ggtggtgtga taggggttgt
    80101 ttcagggatg gtatcaggat tgatcatcac aagatcactc gaatatccct atatcctatc
    80161 cttgttctca gttgtcttga gtttagcgtt ttgttgtatt atagggattg tctttggact
    80221 attaccagcc attaaagcgt ctaagctaga cccaattgaa gcattgcgat ttgaataatc
    80281 aaccaaacaa gcataaaagt caaaaaggat gaccctttga tgtcatcctt agctgcttga
    80341 tacactaaac gccaatctag aaagggaagt tatgtttaaa atattagtag ttgaagatga
    80401 tgataccatc agtcaagtga tttgtgagtt tttaaaagcg aataactatg atccagattg
    80461 tgtatttgat ggccaagctt ccttagacaa gtggcagaca acgtcttatg atctgattat
    80521 tttagacatc atgctccctt ccttaagtgg cttagaagtg ctaaaaacaa ttcgaaagac
    80581 atcagatgtc cctattatta tgctaacggc attagatgac gagtacacac agcttgtaag
    80641 cttcaaccat ttgattagtg attatgtgac taaaccattt tcaccactca ttttaatcaa
    80701 acgtatcgaa aatgtattac gcgtctctac tccagatgaa aagcgccaaa tcggagactt
    80761 acttgttgat gagaccgaac atagcgtcta ttggaaagga acattggtca aactaaccaa
    80821 aaaagaatat gacattattg attatttagc aaaacgtcac caaaagattg tcaccagaga
    80881 ccaattgatg gatgacatat ggggctattc tgaactggac acgcgtgtcc ttgacaacca
    80941 catcaagaac cttcgtaaaa aaatgacggg tattcccctc aagacaatta caggcatggg
    81001 ctatttattg ggagagcgtg agtgagacta atcaaaaaaa cctttttggt catcaatggc
    81061 ttaattattg tagtggttac ctctattttg ttagtgcttt attttgcaat gccaatttat
    81121 tacaccaaag tcaaagacaa agaagttaag cgtgaatttg accaaacaag caagcaaatc
    81181 aaaggcaaga cggtaaccga gattagagat atcctaacaa aaaaaatcaa caaagataat
    81241 atttggtaca gtttagtaga cagtgataac caactgctct atccttcctt gcagctgtta
    81301 gacggcgtca gtgaaagcaa agacagtcaa aatgttaata tcgtcaccac ctttgacaac
    81361 tcttattcta atgttaaggt gatgagtcaa aaagtaaccc tacgcgatgg aaaaaaaatg
    81421 acattgcttg ggcaatcttc acttcaaccc gtaacagatg ctagcaaagt tctccttgac
    81481 ctctacccgt cactattgat tttttcagtg accgtaggga gtattgtcgc ctacttatat
    81541 agtaggactt ctagccggcg tatccttagc atgtcacaaa ccgccaaaaa aatggtcaac
    81601 ctagaaccaa acttaacgtg taccattcac ggcaaagatg aaatagcaat gttggctagt
    81661 gatattaacc gtttgtatgc gagtctttca acgagcatca aatccttgca aaaagagtat
    81721 gaaaaagctt ctgattcaga aagagagaaa tctgagtttt tacgcatgac atcgcacgag
    81781 ctaaagacac caatcaccag tgttattgga atgattgatg gaatgctcta taatgttggt
    81841 gactttgcag atcgtgacaa atatttgcga aaatgccgag acgtccttga agggcaagcc
    81901 caactggttc aatccatttt atctttatct aagattgaaa ccctagcttc tcaaaatcaa
    81961 gaactgtttt cactaaaaag cagcctagaa gaagaaatgg aagtctttct cgtcttatca
    82021 gaactaaaac acctcaaagt gactatcaat ctcgaagaac aattcgtcaa agccaataaa
    82081 gtatacctac taaaggcgat taaaaatatt attgacaatg cctttcacta taccaaatca
    82141 ggcggccaag tgatgattca actaaaagac aaccaactag tgattaaaaa tgaagcagag
    82201 acattattga cacaacagca gatgaaacag ttattccaac cgttttatcg accagattat
    82261 agtcgtaaca ggaaagacgg tggtacagga ttggggctgt ttatcaccca ccagattctt
    82321 gatcagcatc atctggcttc tcgctttgtt gttcttgatc aaagatggat ggtatttacg
    82381 attgattttc catcccatca tgacgattga tccacactag taggacgaca aaagtcatca
    82441 atcattaacc aagccttgac ctttacccat cattgtttag gcaagtataa aaaagaggag
    82501 agaaatcata tatgaagaaa aggaaattgt tagcagtaac actattaagt accatactct
    82561 taaacagtgc agtgccatta gttgttgctg acacctcctt gcgtaatagc acatcatcca
    82621 ctgatcagcc tactacagca gatactgata cggatgacga gagtgaaaca ccaaaaaaag
    82681 acaaaaaaag caaggaaaca gcgtcgcagc acgacaccca aaaagaccat aagtcatcac
    82741 acactcaccc aaccccccct tcaaatgata ctaagcagac cgatcaggca tcatctgaag
    82801 ctactgacaa accaaataaa gacaaaaaca acaccaatca accagacagc agtgatcagt
    82861 ccaccccatc tcccaaagac cagtcgtctc aaaaagagtc acaaaacaaa gatggtcgct
    82921 ctaccccatc acctgatcag caaaaagatc agacacctga taaaacacca gaaaaatcag
    82981 ctgataaaac ccctgaaaaa ggaccagaaa aagcaactga taaaacacca gagccaaatc
    83041 gtgacgctcc aaaacccatc caacctcctt tagcagcagc tcctgtcttt gcaccttgga
    83101 gagaaagtga caaagacctg agcaagctaa aaccaagcag tcgctcatca gcggcttacg
    83161 tgagacactg gacaggtgac tctgcctaca ctcacaacct gttgtcacgc cgttatggga
    83221 ttactgctga acagctagat ggttttttga acagtctagg tattcactat gataaagaac
    83281 gcttaaacgg gaagcgttta ttagaatggg aaaaactaac aggactagac gttcgagcta
    83341 tcgtagctat tgcaatggca gaaagctcac taggtactca gggagttgct aaagaaaaag
    83401 gagccaatat gtttggttat ggcgcctttg acttcaaccc aaacaatgcc aaaaaataca
    83461 gcgatgaagt tgctattcgt cacatggtag aagacaccat cattgccaac aaaaaccaaa
    83521 cctttgaaag acaagacctc aaagcaaaaa aatggtcact aggccagttg gataccttga
    83581 ttgatggtgg ggtttacttt acagatacaa gtggcagtgg gcaaagacga gcagatatca
    83641 tgaccaaact agaccaatgg atagatgatc atggaagcac acctgagatt ccagaacatc
    83701 tcaagataac ttccgggaca caatttagcg aagtgcccgt aggttataaa agaagtcagc
    83761 cacaaaacgt tttgacctac aagtcagaga gctacagctt tggccaatgc acttggtacg
    83821 cctataatcg tgtcaaagag ctaggttatc aagtcgatag gtacatgggt aacggtggcg
    83881 actggcagcg caagccaggt tttgtgacca cccataaacc taaagtgggc tatgtcgtct
    83941 catttgcacc aggccaagca ggagcagatg caacctatgg tcacgttgct gttgtagagc
    84001 aaatcaaaga agatggttcc atcttgattt cagagtcaaa tgttatggga ctaggcacca
    84061 tttcctatcg gacgttcaca gctgagcagg ctagtttgtt gacctatgtc gtaggggaca
    84121 aactcccacg accataaccc cacaaccaag aagctacctg cctgttgacc aatctcaaaa
    84181 agagacagcg tcaacttaga atgaggttca tcagatgata aagaaagtga ccaccccgag
    84241 tcaaaaaaca aaaaaacgtg ttcgtaatgg ctatctccta aaattaggta cagcctgttt
    84301 actcttaagt atactcagtt atggcattgg tcttttgggc cagcctagca tggaaaatac
    84361 gtttatggga atagcgagtg ttgccatgtt aggaagtgtc tgtttcttta ttatctttgc
    84421 tctaaaccgt atctttgacg cactagagga caatttgcga gattagagta ataggtcaaa
    84481 taatcttcca ataatttaga gcacaagcta agttattgga agttttttgt cttttgagag
    84541 ccatgatgcc atcaaaaagc caaatacttc ttatgatgtg agagtcacat ggctaaaatt
    84601 aaaaacaaaa tagaccccaa agccctgttt tctcaaaaca gccaacgaaa aaagacaagt
    84661 taaccagttc ataaaaaaca tcgtagaaac gttttcaaga gctaatgttg gtgtaaattg
    84721 actgaagtat gatagaattt ttaatgaatg tgacaataat gtcacagata aaaaccgaaa
    84781 acagcaaaaa taattaaatt gaatataaaa aagttaatta agtgagtgat aataaagaaa
    84841 tgaagttcaa aaaatataaa taaaataaaa caccagaact gccaaaagca gtgaatgaca
    84901 taaatgtcgt taaaaaaata gatagaagag tctaaaattt cagttttagg tcacgtttta
    84961 tgaatggaaa tcagaatgat gaccttaagt tgtgatttgc gcgtcattga ccgctttcct
    85021 cgttttaatg aaagaatttg aaagatattt tatggtatac ttttccttga tatggttcat
    85081 acggacttga taaatctatt cacaaaaata ataaaaaatt aagataagga catgaagtta
    85141 atgcatgtaa gtaaattgtt tactagccaa caatggagag aattgaaact gatctcatat
    85201 ttaacagaaa actccaatgc tatcggagtt aaagataagg agcttagcaa ggctctcaat
    85261 atttccatgt taacattaca gtcatgcctc actaatatgc agtttatgaa agaagtaggt
    85321 ggaattacct ataaagacgg ctatattaac atttggtatc accagtgttg tgggctacaa
    85381 gaggtctatc aaaaagctct tcgagaatcg ccttctttga aattactgga gcttttgttt
    85441 ttcagagact ttagttcctt agaagagtta gctgaagagc tgtttgtcag cttatctacc
    85501 ctcaaacgcc tcatcaaaaa aaccaacact tacttgtctc atacctttgc tattagtatc
    85561 gtgacaagtc cagtgcaggt atcaggagat gagaggcaaa tccgcctgtt ttacctcaag
    85621 tatttttcag aagcctataa aatctcagaa tggccatttg gggacatttt aaacctgaaa
    85681 aactgtgaac gcctattgag cttattgatc aaagaagtag atgtcaaagt tcattttacg
    85741 ctatttcagc acttaaaaat cttaagtggt gtcaacttga tccgttacta caaggggtat
    85801 tcttgcagtt ataacaataa aaaaaccagt caccgttttt ctcaactcat ccaacattcc
    85861 tcagaaatcc aggatctttc tcgcctgttc tacctcaaat ttgggttaca tctcgacgag
    85921 tataccatag ctgaaatgtt ttctaaccat cttaacgaca agctagaaat tggctgtgct
    85981 tttgagatta tcaatcaaga cccaacatca ggaggcagac aagtaaccaa ctggatccat
    86041 ctattagatg agatggaaat caagctcaat ctcagcatca ccaataaata cgaagttgcc
    86101 gtaaccctcc ataacgcttc ggtgttaaac gaagaagaca ttacagccaa ttatttgctg
    86161 tttgattata aaaagagtta cctgaacttt taccaaaaag aacaccctcg tatctatgag
    86221 gcctttgtga caagtgtcga gaagctgatg caggcagata atgctcaagt tagcaaagaa
    86281 ctgatcaatc agctcactta ttgtttcttt attacctggg aaaatagttt cttaaaagta
    86341 aatcaaaaag atgaaaaagt acgactccta gtgatagaga gaagttacaa tagtgtcggt
    86401 aattttttga aaaagtacat cggtgagttt ttcagcatta ctaattttga tgagttagat
    86461 tgtttgacaa ttgatctagt agagattgaa aaacagtacg atgttatcgt gacagatgtt
    86521 atggtgggta aaagcgaaga gttagagatt ttctttttct acaagatgat cccagaagct
    86581 attattgata gattaaacga atttttgaac gttagtttca cagataacaa cgttatggtc
    86641 aaaaacctcg aagccccttc cccttcaaaa tctcatagcg acaaagaggt acaaaaacca
    86701 gaaaagccag acaattcagt taaacaagca acatcatcat aggatttcag acgtcatggt
    86761 aagaaaaaaa gaatcattta cagcccatag aggtaaggtc aaaagctgaa aacagctcaa
    86821 aaaaactgac ctttaccttt tggctttttt tatttagaat aattttattg gagagatgct
    86881 taataattta agcacaattc ttagaaagtt aagaaataag gagtaaacaa tgtctaaaag
    86941 aaatccaaac aaacactact cactgagaaa gttaaaaaca ggtactgcat cagtagcagt
    87001 agctttgaca gttttgggga ctggattagc aaacacaact gatgtaaagg ctgacttaag
    87061 tactcaggaa catcctagag taacaaaagc gagagaagaa gctctcgagg aagttttacg
    87121 tagttgggat tatggatctg taaaagctgc cttggcaggc tcttatcgta aaaacttaca
    87181 acttgaaaac actattaagc agaaagataa agaattatct ttcttatcca aagttttgga
    87241 tgaggctgca aaaaaatata gagaatctag cgacaagtat aaacaagaga ttggacagct
    87301 aaaagcagca gcagaagcag aagctcaaaa agcattagat gcactaaata acaaaaacaa
    87361 gcaaatctca gacttaacca acgaaaacgc acagttaaaa gaagccattg aaggttatgt
    87421 gcaaactatc caaaacgcta gtcgtgaaat cgcagcaaaa caacaagaac ttgcagctgc
    87481 aaaaagccag ttagaggcaa aaaatgctga gattgaggca ttgaaacaac aagatgcctc
    87541 taagactgag gaaattgcta aattgcaatc agaggcagcg actttagaaa acctcctagg
    87601 ttcagctaag catgagttga ctgacttgca agctaagcta gatacagcaa ctgctgaaaa
    87661 agcaaaacta gaatcacaag taacaacctt agaaaacctc ctaggttcag ctaagcgtga
    87721 attgactgat ctgcaagcta agctagatgc agctaatgct gaaaaagaaa agcttcaatc
    87781 acaagcagca gccctagaaa aacaactaga agcaactaaa aaagagttag ctgatttaca
    87841 ggctaaatta gcagcaacca accaagaaaa agaaaagtta gaagctgaag caaaagctct
    87901 taaagagcaa ttagcaaaac aagctgaaga gcttgctaag ctaaaagcag ataaagcttc
    87961 aggagctcaa aaaccagata ctaaacctgg caataaagag gttccaacaa gaccatcaca
    88021 aacaagaaca aacactaata aagctcctat ggctcaaaca aagagacaat taccgtcaac
    88081 aggcgaagaa acaaccaacc cattcttcac tgcagcagca ttgacagtga tcgcatctgc
    88141 aggcgtactt gccctaaaac gcaaagaaga aagctaagcc caactcacaa tatcttttct
    88201 agcccaagaa aaaaacaaaa aaagaggaag accattcctc tttttttgaa cggttgaaaa
    88261 gcaaaaaggt caaaaaggta ctaaagtctc aaaaacctgg tctttacctt ttaccgctta
    88321 ttctttagaa tagaattatt agagagaagt cttagaaaaa tgaggctaat tccctaaaga
    88381 tgaaaaaata aggagcaaat aatggctaga aaagatacga ataaacagta ttcgcttaga
    88441 aaattaaaaa caggtacagc atcagtagcg gtcgctgtgg ctgttttagg agcaggcttt
    88501 gcaaaccaaa cagaagttaa ggctgcggag tcgcgaagcg tttctcaagg tagcgtgagc
    88561 ctagagctat atgataagct atcggatgaa aatgatattc ttagagaaaa acaagacgag
    88621 tatctaacaa aaattgacgg gttagataaa gaaaataaag agtatgcaag tcaacttgct
    88681 aaaaatcaaa aggaacgcga agaattagag ctcgaatacc tcagaaaatc agataaagag
    88741 tataaagagc atcaacaata tcgacaagaa caagaagaac gtcaaaaaaa tcaagaacaa
    88801 ttagaacgta aatatcaacg agaagtagaa aaacgctatc aagaacaact ccaaaaacaa
    88861 caacaattag aaacagaaaa gcaaatctca gaagctagtc gtaagagcct aagccgtgac
    88921 cttgaagcgt ctcgtgcagc taaaaaagag cttgaagctg agcaccaaaa actcaaagag
    88981 gaaaaacaaa tctcagacgc aagccgtcaa ggcctaagcc gtgaccttga agcgtctcgc
    89041 gaagctaaga aaaaagtaga agcagactta gccgaagcga atagcaaact tcaagccctt
    89101 gaaaaactaa acaaagagct tgaagaaggt aagaaattat cagaaaaaga aaaagcagag
    89161 ttacaagcaa aactagaagc tgaagcaaaa gctcttaaag agcaattggc taaacaagct
    89221 gaagaacttg ctaaactaaa aggcaaccaa acaccaaacg ctaaagtagc cccacaagct
    89281 aaccgttcta gatcagcaat gacgcaacaa aagagaacgt taccgtcaac aggcgaaaca
    89341 gctaacccat tctttacagc agcagctgca acagtgatgg tatctgcagg tatgcttgct
    89401 ctaaaacgca aagaagaaaa ttaagctatt agactgatgc taaagctaag agagaatcaa
    89461 atgattctct ctttttgagt gactaagtaa ctaacaatct cagttagacc aaaaaatggg
    89521 aatggttcaa aaagctggcc tttactcctt ttgattaacc atatataata aaaacattag
    89581 gaaaataata gtaatattaa gtttgtttcc tcaataaaat caaggagtag ataatggcta
    89641 gacaacaaac caagaaaaat tattcactac ggaaactaaa aaccggtacg gcttcagtag
    89701 ccgttgcttt gaccgttttg ggcgcaggtt ttgcaaacca aacagaagta agagctgaag
    89761 gggtaaaagc gactaagaac ttgtcagagg aggctaaata tgccgcattg agagacgaga
    89821 atactggttt acgtggtgat cagacaaaat tagtaaaaaa acttgaagaa gaacaagaga
    89881 agagcaaaaa tctagaaaag caaaaacaag agttagaaaa ccaagccctt aactttcaag
    89941 atgtaattga aactcaggaa aaagaaaaag aagatctcaa aacaacttta gctaagacta
    90001 ctaaagaaaa tgagatttca gaagctagcc gtaaagggtt aagccgagac ttagaagctt
    90061 ctcgtgcagc taaaaaagaa ctagaagcta agcaccaaaa attagaggct gatcaccaag
    90121 ccctagaagc taagcaccaa aaattagcag aagaacatca agtttcagag actagccgca
    90181 agggtctaag tcgtgacctt gaagcgtctc gtgaagctaa taagaaggtt acatctgagt
    90241 taacacaagc aaaagctcaa ctctcagcgc ttgaagaaag taagaaatta tcagaaaaag
    90301 aaaaagctga gttacaagca aaactagatg cacaaggaaa agccctcaaa gaacaattag
    90361 caaaacaaac tgaagagctt gcaaaactaa gagctgaaaa agcagcaggt tcaaaaacac
    90421 ctgctaccaa accagctaat aaagaaagat taggtagagc tgctcaaaca gctacaagac
    90481 ctagccaaaa taaaggaatg agatcacaat taccgtcaac aggcgaagca gccaacccat
    90541 tctttacagc agcagctgca acagtgatgg tatctgcagg tatgcttgct ctaaaacgca
    90601 aagaagaaaa ctaagccttt agaacttggt ttttgtaacg gtgcaataga caaaagcaag
    90661 caaggccaaa aactgagaaa gtcctaaaaa gctggccttt acccctcaaa attaatgttt
    90721 tataataaag atgttagtaa tataattgat aaatgagata catttaatca ttatggcaaa
    90781 agcaagaaaa atagctgtat catatgcaaa taacccctgt ttgctcttta aaaaagacgt
    90841 tatccttatt tctccacgca cagatggaca gctaggagag aatcgtttga ttctctcttt
    90901 tcttaatggt cataaagaca aagtctctca tcatgaaagg acgacacatt gcgtaaaaaa
    90961 caaaaattac catttgataa acttgccatt gcgctcatgt ctacgagcat cttgctcaat
    91021 gcacaatcag acattaaagc aaatactgtg acagaagaca ctcctgctac cgaacaagcc
    91081 gtagaaatcc cacaaccaac agcggtttct gaggaagcac catcatcatc aaaggaaact
    91141 aaaaccccac aaactcctag tgatgcagaa gaaacagtag cagatgacgc taatgatcta
    91201 gcccgtcaag ctcctgctaa aattgctgat accccagcaa cctcaaaagc gactattagg
    91261 gatttgaacg acccttctca ggtcaaaacc ctgcaggaaa aagcaggcaa gggagctggg
    91321 actgttgttg cagtgattga tgctggtttt gataaaaatc atgaagcgtg gcgcttaaca
    91381 gacaaaacta aagcacgtta ccaatcaaaa gaagatcttg aaaaagctaa aaaagagcac
    91441 ggtattacct atggtgagtg ggtcaatgat aaggttgctt attaccacga ctatagtaaa
    91501 gatggtaaaa ccgctgttga tcaagagcac ggcacacacg tgtcagggat cttgtcagga
    91561 aatgctccat ctgaaacgaa agaaccttac cgcctagaag gtgcgatgcc tgaggctcaa
    91621 ttgcttttga tgcgtgtcga aattgtaaat ggactagcag actatgctcg taactacgct
    91681 caagctatca gagatgctgt caacttggga gctaaggtga ttaatatgag ctttggtaat
    91741 gctgcactag cctatgccaa ccttccagac gaaaccaaaa aagcctttga ctatgccaaa
    91801 tcaaaaggtg ttagcattgt gacctcagct ggtaatgata gtagctttgg gggcaagacc
    91861 cgtctacctc tagcagatca tcctgattat ggggtggttg ggacacctgc agcggcagac
    91921 tcaacattga cagttgcttc ttacagccca gataaacagc tcactgaaac tgctacggtc
    91981 aaaacagacg atcagcaagc taaagaaatg cctgttcttt caacaaaccg ttttgagcca
    92041 aacaaggctt acgactatgc ttatgctaat cgtgggatga aagaagatga ttttaaggat
    92101 gtcaaaggta agattgccct tattgaacgt ggcgatattg atttcaaaga taagattgca
    92161 aacgctaaaa aagctggtgc tgtaggagtc ttgatctatg acaatcagga caagggcttc
    92221 ccgattgaat tgccaaatgt tgaccagatg cctgcggcct ttatcagtcg aaaagatggt
    92281 ctcttattaa aagacaatcc ccaaaaaaac atcaccttca atgcgacacc taaggtattg
    92341 ccaacagcaa gtggcaccaa actaagccgc ttctcaagct ggggtctgac agctgacggc
    92401 aatattaagc cagatattgc agcacccggc caagatattt tgtcatcagt ggctaacaac
    92461 aagtatgcca aactttctgg aactagtatg tctgcgccat tggtagcggg tatcatggga
    92521 ctgttgcaaa agcaatatga gacacagtat cctgatatga caccatcaga gcgtcttgat
    92581 ttagctaaaa aagtattgat gagctcagca actgccttat atgatgaaga tgaaaaagct
    92641 tatttttctc ctcgccaaca aggagcagga gcagtcgatg ctaaaaaagc ttcagcagca
    92701 acgatgtatg tgacagataa ggataatacc tcaagcaagg ttcacctgaa caatgtttct
    92761 gataaatttg aagtaacagt aacagttcac aacaaatctg ataaacctca agagttgtat
    92821 taccaagcaa ctgttcaaac agataaagta gatggaaaac actttgcctt ggctcctaaa
    92881 gcattgtatg agacatcatg gcaaaaaatc acaattccag ccaatagcag caaacaagtc
    92941 accgttccaa tcgatgctag tcgatttagc aagaacttgc ttgcccaaat gaaaaatggc
    93001 tatttcttag aaggttttgt tcgtttcaaa caagatccta caaaagaaga gcttatgagc
    93061 attccatata ttggtttccg aggtgatttt ggcaatctgt cagccttaga aaaaccaatc
    93121 tatgatagca aagacggtag cagctactat catgaagcaa atagtgatgc caaagaccaa
    93181 ttagatggtg atggattaca gttttacgct ctaaaaaaca actttacagc acttaccaca
    93241 gagtctaacc catggacgat tattaaagct gtcaaagaag gggttgaaaa catagaggat
    93301 atcgaatctt cagagatcac agaaaccatt tttgcaggta cttttgcaaa acaagacgat
    93361 gatagccact actatatcca ccgtcacgct aatggcaagc catatgctgc gatctctcca
    93421 aatggggacg gtaacagaga ttatgtccaa ttccaaggta ctttcttgcg taatgctaaa
    93481 aaccttgtgg ctgaagtctt ggacaaagaa ggaaatgttg tttggacaag tgaggtaacc
    93541 gagcaagttg ttaaaaacta caacaatgac ttggcaagca cacttggttc aacccgtttt
    93601 gaaaaaacgc gttgggacgg taaagataaa gacggcaaag ttgttgctaa cggaacctac
    93661 acctatcgtg ttcgctacac tccgattagc tcaggtgcaa aagaacaaca cactgatttt
    93721 gatgtgattg tagacaatac gacacctgaa gtcgcaacat cggcaacatt ctcaacagaa
    93781 gatcgtcgtt tgacacttgc atctaaacca aaaaccagcc aaccgattta ccgtgagcgt
    93841 attgcttaca cttatatgga tgaggatctg ccaacaacag agtatatttc tccaaatgaa
    93901 gatggtacct ttactcttcc tgaagaggct gaaacaatgg aaggcggtac tgttccattg
    93961 aaaatgtcag actttactta tgttgttgaa gatatggctg gtaacatcac ttatacacca
    94021 gtgactaagc tattggaggg tcactctaat aagccagaac aagatggttc agatcaagca
    94081 ccagacaaaa aaccagaaac taaaccagaa caagatggtt cagatcaagt accagacaaa
    94141 aaaccagaaa ctaaaccaga acaagacggt tcaggtcaag caccagacaa aaaaccagaa
    94201 gctaaaccag aacaagacgg ttcaggtcaa acaccaaata aaaaaccaga aactaaacca
    94261 gaaaaagata gttcaggtca aacaccaggt aaaactcctc aaaaaggtca accttctcgt
    94321 gctctagaga aacgatcttc taagcgtgct ttagctacaa aagcatcaac aagagatcag
    94381 ttaccaacga ctaatgacaa ggatacaaat cgtttacatc tccttaagtt agttatgacc
    94441 actttcttct tgggattagt agctcatatc tttaaaacaa aacgcactga agattagtac
    94501 aactgatcag atggctacta ttgatgatga gttagatcag tcttcttttc aaaagaaggc
    94561 atagcagtat aaaaatagat atgtgaggac aatatgcgta gagcagaaaa taacaaacac
    94621 agccgctatt ccattcgcaa actgagcgtt ggggtaacga gtatagcaat tgcgagtctc
    94681 tttttgggaa aagttgccta tgccgtagat agcatgcagc caatctcttc gactcaagga
    94741 aacagagcca atacatccaa aaaatggtat gatattaatg agtatggtct tattcctgta
    94801 gatataagct ttgaagctgc caaaaaagat tttaaagaag aagtagaaaa atcacttttg
    94861 tctgaagaac aacagaaaac gtataatcaa aaaattgaag ctgcaaaaaa caaagacgac
    94921 ctattgttaa cgtatcatag tgagtactct aaagatatta agaaacactc aacgtctact
    94981 gagccagttg aggcatctgt gcaggagaca caggcatcag tttcagattc gatggtgaca
    95041 gatgattcaa catcagttac ggctgattct cctgagaaaa caccatctcc agaaacaccg
    95101 gctccatcaa ttccagaggt cccagcagcc ccagcttcat cacctgagag tgaggagtct
    95161 tcagtagcat cttctgagga aacctcatct ccagaaactc cagtggcccc agaagcccca
    95221 gctttatctg aggctccagc tcaaccagct gagagtgagg agtcttcagt agcagcttct
    95281 tctgaggaaa ccccatctcc agaaactcca gcggctccag aaactcctga agaaccagca
    95341 gctccagctc aaccagctga gagtgaagaa tcttcagtag cagctacgac aagcccgtct
    95401 ccatcaactc cagccgaatc agagactcag acgccaccag ctgttactaa agactctgat
    95461 aagccatctt cagcagctga aaaaccagca gcctcttcac ttgtttcaga acaaaccgtt
    95521 caacaaccaa cttcaaagag atcttctgat aaaaaagaag agcaagaaca gtcttactct
    95581 ccaaatcgct cattgtcaag acaggttagg gcccatgagt caggtaagta cttgccttca
    95641 acaggtgaaa aagcacagcc actctttata gctactatga ctttgatgtc tctatttggc
    95701 agtcttttag tcacaaaacg ccaaaaagaa actaaaaaat agtattactt aaactgataa
    95761 gagcttattt aatagagaga accaatttgg ttctctctat ttttttagat gtgctgcctc
    95821 atcaaaaaga agttaggaca aatagctgtc aacaattgtc ttttgcttat ctcttcagtt
    95881 gctgtgattt tatcatacag tgataaaaga tggtagttgc cattgacaaa gcattgataa
    95941 aggagtaaaa ttaactggtt aataactggt taaattataa ttgaggaggt actatgaaaa
    96001 aaggtttttt tctcatggct atggttgtga gtttagtaat gatagcaggg tgtgataagt
    96061 cagcaaaccc caaacagcct acgcaaggca tgtcagttgt aaccagcttt taccccatgt
    96121 atgcgatgac aaaagaagta tctggagacc tcaatgatgt gaggatgatc caatcaggtg
    96181 caggcattca ttcctttgaa ccgtctgtaa atgatgtggc agctatttat gacgcggatt
    96241 tgtttgttta ccattcacat accttagaag cttgggcaag ggatctagac cctaatttaa
    96301 aaaaatcaaa ggttgatgtg tttgaagcgt caaaaccttt gacactagat agagtcaaag
    96361 ggctagaaga tatggaagtc acacaaggca ttgaccctgc gacactttat gacccacata
    96421 cctggacgga tcccgtttta gctggtgagg aagctgttaa tatcgctaaa gagctaggac
    96481 gtttggatcc taaacacaaa gacagttaca ctaaaaaggc taaggctttc aaaaaagaag
    96541 cagagcaact aactgaagaa tacactcaaa aatttaaaaa ggtgcgctca aaaacattcg
    96601 tgacgcagca cacggcattt tcttatctgg ctaaacgatt cggcttgaaa caacttggta
    96661 tctcgggtat ttctccagag caagagccct ctcctcgcca attgaaagaa attcaagact
    96721 ttgttaaaga atacaacgtc aagactattt ttgcagaaga caatgtcaat cccaaaattg
    96781 ctcatgctat tgcgaaatca acaggagcta aagtaaagac attaagtcca cttgaagctg
    96841 ctccaagcgg aaacaagaca tatctagaaa atcttagagc aaatttggaa gtgctctatc
    96901 aacagttgaa gtaaaggaga ttattagtga agaaaacata tggttatatc ggctcagttg
    96961 ctgccatttt actagctact catattggaa gttaccaact tggtaagcat catatgggtt
    97021 cagcaacaaa ggacaatcaa attgcctata ttgatgatag caaatgtaag gcaaaagccc
    97081 ctaaaacaaa caaaacgatg gatcaaatca gtgctgaaga aggcatctct gctgaacaga
    97141 tcgtggtcaa aattactgac caaggctatg tgacctcaca cggtgaccat tatcattttt
    97201 acaatgggaa agttccttat gatgcgatta ttagtgaaga gttgttgatg acggatccta
    97261 attaccattt taaacaatca gacgttatca atgaaatctt agacggttac gttattaaag
    97321 tcaatggcaa ctattatgtt tacctcaagc caggtagcaa gcgcaaaaac attcgaacca
    97381 aacaacaaat tgctgagcaa gtagccaaag gaactaaaga agctaaagaa aaaggtttag
    97441 ctcaagtggc ccatctcagt aaagaagaag ttgcggcagt caatgaagca aaaagacaag
    97501 gacgctatac tacagacgat ggctatattt ttagtccgac agatatcatt gatgatttag
    97561 gagatgctta tttagtacct catggtaatc actatcatta tattcctaaa aaggatttgt
    97621 ctccaagtga gctagctgct gcacaagcct actggagtca aaaacaaggt cgaggtgcta
    97681 gaccgtctga ttaccgcccg acaccagccc cagccccagg tcgtaggaaa gccccaattc
    97741 ctgatgtgac gcctaaccct ggacaaggtc atcagccaga taatggtggc tatcatccag
    97801 cgcctcctag gccaaatgat gcgtcacaaa acaaacacca aagagatgag tttaaaggaa
    97861 aaacctttaa ggaactttta gatcaactac accgtcttga tttgaaatac cgtcatgtgg
    97921 aagaagatgg gttgattttt gaaccgactc aagtgatcaa atcaaacgct tttgggtatg
    97981 tggtgcctca tggagatcat tatcatatta tcccaagaag tcagttatca cctcttgaaa
    98041 tggaattagc agatcggtac ttagccggcc aaactgagga caatgactca ggttcagatc
    98101 actcaaaacc atcagataaa gaagtgacac atacctttct tggtcatcgc atcaaagctt
    98161 acggaaaagg cttagatggt aaaccatatg atacgagtga tgcttatgtt tttagtaaag
    98221 aatccattca ttcagtggat aaatcaggag ttacagctaa acacggagat catttccact
    98281 atataggatt tggagaactt gaacaatatg agttggatga ggtcgctaac tgggtgaaag
    98341 caaaaggtca agctgatgag cttgctgctg ctttggatca ggaacaaggc aaagaaaaac
    98401 cactctttga cactaaaaaa gtgagtcgca aagtaacaaa agatggtaaa gtgggctata
    98461 tgatgccaaa agatggcaag gactatttct atgctcgtga tcaacttgat ttgactcaga
    98521 ttgcctttgc cgaacaagaa ctaatgctta aagataagaa acattaccgt tatgacattg
    98581 ttgacacagg tattgagcca cgacttgctg tagatgtgtc aagtctgccg atgcatgctg
    98641 gtaatgctac ttacgatact ggaagttcgt ttgttatccc acatattgat catatccatg
    98701 tcgttccgta ttcatggttg acgcgcgatc agattgcaac aatcaagtat gtgatgcaac
    98761 accccgaagt tcgtccggat gtatggtcta agccagggca tgaagagtca ggttcggtca
    98821 ttccaaatgt tacgcctctt gataaacgtg ctggtatgcc aaactggcaa attatccatt
    98881 ctgctgaaga agttcaaaaa gccctagcag aaggtcgttt tgcaacacca gacggctata
    98941 ttttcgatcc acgagatgtt ttggccaaag aaacttttgt atggaaagat ggctccttta
    99001 gcatcccaag agcagatggc agttcattga gaaccattaa taaatctgat ctatcccaag
    99061 ctgagtggca acaagctcaa aagttattgg caaagaaaaa cgctggtgat gctactgata
    99121 cggataaacc caaagaaaag caacaggcag ataagagcaa tgaaaaccaa cagccaagtg
    99181 aagccagtaa agaagaagaa aaagaatcag atgactttat agacagttta ccagactatg
    99241 gtctagatag agcaacccta gaagatcata tcaatcaatt agcacaaaaa gctaatatcg
    99301 atcctaagta tctcattttc caaccagaag gtgtccaatt ttataataaa aatggtgaat
    99361 tggtaactta tgatatcaag acacttcaac aaataaaccc ttaaccaaaa gaagatttca
    99421 ttgttaaagc actgctttgt caaagcaagt tacggtgatt ttgaagtcat tctatgtaac
    99481 gagtagtgat aaaagttgga taatagcggt tttcttttgc aaagaaattg tatccatgtt
    99541 agaataataa aaaaaagagg aggattctaa tcatgtcaga agaaaaatta aaatcaaaaa
    99601 ttgagcaagc atctggtggc ctaaaagaag gtgctggtaa gttgacaggt gataaagagc
    99661 tagaagcaaa aggatttgtt gaaaaaacaa ttgctaaagg caaagaactt gcagacgatg
    99721 caaaagaagc ggttgaaggt gctgtagatg ccgttaagga aaaattaaaa taattaaaaa
    99781 aaccagctta cagctggttt ttttaatggt gtgattttgt taggaaaaga ctcaataggt
    99841 aataaccata ggtgttaggt atgcttgaac agttgagttc gattctcttc aatcatatag
    99901 cacgcgtcac aaagtttttc taacatatca aaatcatgac taataatgat gagacctaaa
    99961 tttctatcct ttacaatctc caacaggttt ttccatacac tagcttgtgt aatgctatcc
   100021 aacatagtag tcatttcatc tgcaataagg tatttcgtct ctggatgtaa tgaacgcaca
   100081 atcgaaaagc gttgcaattc ccctcccgag agttcactag gacgacgctt tagccatttt
   100141 tcttgaatgc caaaagcatc tcgcaaatct tgacttggat agtaggcttc ttccaaactt
   100201 tttttcatag gccataaagg attcatggtt tgttcaggat gttgttggat aagttgtaca
   100261 ggtctaaatg ctttgttagg caaatgactg ccatcaacta atacttcacc agatttaggc
   100321 tgcaaaaaac cagcaagcac tctggataaa ctcgtttttc cacacccact ttgtccaaat
   100381 atccctaaga tttgaccagg tgctacctct aaatcaatct ccttaaaaag ccattgatct
   100441 tttttatgat aaaagccaag ctttttagcc tctaaggtca tgagtaactc ctttcaaaaa
   100501 gtcttgctga gggagtgtgc gccataaacg tctcgcaaat tctgtttgta attgctcccc
   100561 acctccgcta aaaaagctag ctggggctgt ttcaatagct tttccctctt taaaaatagt
   100621 tatacgatcc gcaatttgac tagctgctac aatatcatgg gtgataaaga tgacgcttat
   100681 tcctttatct gcaaaggagc gtagttgatc taaaaccatt ttcagagcat ctggatgtaa
   100741 tccaggggtg ggctcatccg caataatcaa agaaaccgta tcactaatac acgttgtaaa
   100801 caaaacacgt cggagcattc cgccagaaag ttggaaagga tacaagtcac catcactttc
   100861 ttttaatcca aactgttgaa ataatccttc ttgagtagcc ttagcatttt ctgagatacc
   100921 caagcgcacc tgatgcttga ctttcataga tggatctaaa taattaacgg attgtggaat
   100981 caacgtcatt tcttttcctc gcaactgttt gatgcgttta gaagttagtg attgaccacg
   101041 ataaatcata tctcctgtta cagctgcatt tttaggaaga atatccataa tagcatgtgc
   101101 taataaactc ttgcctgaac cactagcacc tataatagct aataactcac cttttttaac
   101161 ttctaaattc agcgcttgga tcggtgtgga ttgaaatggt tttaaaaatc ttccgtattg
   101221 agtgaaggtg atggagaggt ctttaatgct taataatgtt tctgtcatat ctctacctcc
   101281 taaaaatgat ccgtttgagg gtaaaagagt ttctttaaag attctccgat agtatcaaag
   101341 gcattgacaa ctaaaataag ataaaggcct ggaaaaatca ccaaccacca attgccaaga
   101401 gagatatgct tagctgcttc tgacaaaatg ataccaaccg aaggttgttc ggcagaaagg
   101461 ccaaatccta agaaagtcat ggatgcttca tgcaagatga cgtgcggaaa taagaggata
   101521 aacccaatga aaatttgaga agcaatcaaa ggcaggatat gatgcctcac aatataataa
   101581 ggcgtttttc ccatgctttt agagagctgg acaaaggctt tattctttag atcatagact
   101641 tcattgcgga taagccttgc tagagagggc caatgggtaa cagccgttgc aatgataacc
   101701 ccttgagccc ctttcccaac aacaaaagaa atgagaatca taaaaatcaa atgaggcata
   101761 ccaataaaca aatcaaccaa ccaggctatt attttatcaa taaggctatt tcctagacct
   101821 gcaagcactc caaaaacggt cgcaagaaag actcccataa gggcacctaa taagccgact
   101881 tgtaaagaga aataaagccc tttaatcgtt ctgacaaaca tatccctacc taaaccatct
   101941 gtcccaaaaa gatggtttaa ggaaggagcg aggttgcgta aagctgcatt ggtttccaaa
   102001 ggcgtcctat agaaataaag gtttaaggct agaatactaa gaatgagaga aatggcgata
   102061 cctagttgcc ataaaaccat cgttcgacgt ttcaatatca tacttttctc cttaactgtg
   102121 gattgatgat gctatttaaa atatccgaaa taagattgcc cgcaaaaaca aataatgtcc
   102181 ctatcatcac aatagctaga aggagcggtg tatcactttt aagtcctgct tcagtgaggg
   102241 tagaccctaa gccaggatat gagaaaactt gctcagcaag aacagatcct ccaaacaatt
   102301 ctccaaaata ggaaaaatgc agtgtaatag ctggtacgat agcatttcta aggcaatgat
   102361 gtttaaaaat ttgccactgt gtttccccac gcgctctggc aaataagaca tattcactag
   102421 aaagcaccga catcatttta gttctcgtat gaagggtgac attagcaata cctagaatac
   102481 ttagcgtgaa aacaggtaac ataaggtgct taatccgatc agctaacgta atatcttgac
   102541 ttaaagtccc aatcggggaa gaaataccaa tcgggaacca ccccagctgg acagaaaaga
   102601 ttaataaaaa aatgaggcca atccaaaacg ttggtactga tatctgaagg taagaaaacc
   102661 acctgacaac tcgatcaagt aatttccctt gatggaaagc ggataacgtt cctaagataa
   102721 atccaataag acccgataag atccaagaga gtcccataag tatgaaagaa gcacctgccc
   102781 gtgatctaat aatatcacta acaggttgcc gataaacgag cgaggtccct aaatctccct
   102841 gtatcacatt tttcaaccaa ataaaatatt ggactagagc tggcttatcc aagccatagt
   102901 ggtgagcaat cgctttgtac tgagcagggg ttagtgatgt gtcataattg acacttgcca
   102961 tgacgggatc tactggagat tgttttaaca aaacgaaggt caaaacagat accccaaaaa
   103021 taagcgtgac acatctgatg attttccaga tgataataat ggtagtacgt ttcacaatga
   103081 aacctcctta atcgataaga aaaggagccg aggaaacgat cagcacagtt ttgtgtatct
   103141 tgttttctca gactccaaac ttaaagtcgc tgtattaact aaacgcgtta cttagttgat
   103201 tcatcccaag tccactcggc aatgttagtc aataatgacc aatcatgacc atgactgtgg
   103261 atgccttgtt tacctacatt gatacgttta tcaccaatat aagtatggtt aaggctcact
   103321 aaccatacat ttggcaaatc tccaagagta gaagcacctg ttttgccatc ccactgcgct
   103381 aacttccaat attcgttagc tttgtcaagg tcagaagatg tcattgcttt gtcaaggtac
   103441 ttagtcacgg taggattgtt ataaaacgta atattggtcc aacctttacc tgctaggctt
   103501 ggatgatgtg attcataaaa ttgctgcgcg tgatgacgtc ctccggcata aagtaaggct
   103561 gagtcatgtg acttcgttgc catttcatcc cagttactag ctttgagttt aatagtaatc
   103621 cctagggctt tggcttgctc tgctacttca acggctaagt tcgctcgcaa ttgatcatta
   103681 gtagggtagt acagatcaaa cgctgcatca aggtcacctt ttttacggct accgtctgct
   103741 tgttctttcc atcccgcttt tgtcaacaat tgcttagctt tagctacttt attatcttta
   103801 atggctgttt ttggattcca aaatggtgtt ttatcaataa ttgaataagc tggtttacca
   103861 taaccattta aaaccgtatc gagaactttt tgtctattta aaccaatagt caaggctttt
   103921 cggattgctg gatcactagt gacatcattt cctacaggat agccatcagg agaatcagtg
   103981 atgacgcctt ttttcacata aggtaatgat aagccgcgca catcatttga tggaatgtca
   104041 aggaggcgag tgcctttgac ttttttatca gcaagttctg gcgttgcgta gatcatatca
   104101 acatcaccag attctaaagc tgctagtgct gtgttttcat caagtaagac ccaagtccac
   104161 tttttaaagt atggtttttt cccatgccaa taagggttac gaacaaaaat agcttgttct
   104221 ccagccttat attcttttac catgtaaggt cctgaaccga taggattgct cttatactta
   104281 tcattgtaat gttttttagg gacgattggg atttcagtca actgtgctgt aaatgtcgaa
   104341 tgcgcctcag tcaaatggat attgacctga tttttcccaa ctacttcaac gttcttgatg
   104401 aaggttagat cccaagcttt tccatctgct ttcaacatat cataagtaaa cttaacatcg
   104461 tcagcagtaa caggctcacc atttgagaat ttaaaatcat catgcaagtc aaacgaccaa
   104521 gtcagcccat cttcagagag atggtatgtt ttagcaagct ctcctattat atctagttca
   104581 ggagaacgtt tcaatagagt gctatgagtg atattccctt cattgtggac tccataacgg
   104641 tcctttggat cgaattcatg agggagcttt gcccccatag aaacgacaag ttcgtctttt
   104701 ggacgttgtt tgcgctgacg ttcttttgtt tgaggctttt gttgttgaca tgcaactaaa
   104761 ataagcccag tcaaaaataa cgtgataata gagaagtatt ttaggtattt tgacacaatc
   104821 aaatctcctt atttctaatt aataaataat aatagtaacg actccatctc attatagcaa
   104881 taaacaaata ggagggcaat tgtttaactg gttaattaga atttttgtta ttttcaggaa
   104941 gatactcagg gcttttttat aagttgatgt attaacaaaa gataaagagg tttcatgact
   105001 tattttagat taaaaaaaga attaaactgg tcactaagaa gtaaagggat tgtagtttac
   105061 gaagggaatc aaaaacctca gatagccatt aatacaggta aaaacgaaga actatttaag
   105121 ttcctgatgt tcttatcaga ttttaaaaat agtcaagaaa ttaaaaacta ttcggcttta
   105181 acagaaatag agaaaaaaga tgctattaac tatttaacaa caaaaaattt ttaacaatca
   105241 ttggatcatc caatgaacct agatagaaca gatttatttg tcaattcttt tccagatata
   105301 agttttattt atactttgtt attggtgttt caaacatggt atgagacttt tgtaaggcaa
   105361 aggatgttag ctgaccttag aagagatatt ataaagagtt acgccgcaaa tagtcctatt
   105421 gtttagcagt ttgaacggcg taagtataag gtgtcactga ttacctttct tatttttttc
   105481 atcactgatc actgattttt tgttgttcag ctagaacttt tttaagatct tgttcaagtt
   105541 caattttttc ttcattagtt aagttatcag ataatattag gttataattc aatagagaga
   105601 gttgtaactt cttggtta
//
LOCUS       DAUNLR010000002       102881 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUNLR010000002 DAUNLR010000000
VERSION     DAUNLR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102881
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.002"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(273..821)
                     /gene="raiA"
                     /locus_tag="VLL59_000089"
     CDS             complement(273..821)
                     /gene="raiA"
                     /locus_tag="VLL59_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HER6508253.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
     gene            complement(901..1566)
                     /locus_tag="VLL59_000090"
     CDS             complement(901..1566)
                     /locus_tag="VLL59_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HER6508254.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPDCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLIEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            complement(1538..2863)
                     /locus_tag="VLL59_000091"
     CDS             complement(1538..2863)
                     /locus_tag="VLL59_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6508255.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVISRGKMICQRCH
                     YQLDEEARLPNGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            2919..3551
                     /locus_tag="VLL59_000092"
     CDS             2919..3551
                     /locus_tag="VLL59_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HER6508256.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNSQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            3679..4620
                     /gene="cysK"
                     /locus_tag="VLL59_000093"
     CDS             3679..4620
                     /gene="cysK"
                     /locus_tag="VLL59_000093"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HER6508257.1"
                     /translation="MTKIYKTITELVGQTPIIKLNCLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEVAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLIGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(4638..5015)
                     /locus_tag="VLL59_000094"
     CDS             complement(4638..5015)
                     /locus_tag="VLL59_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HER6508258.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(5015..6415)
                     /locus_tag="VLL59_000095"
     CDS             complement(5015..6415)
                     /locus_tag="VLL59_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HER6508259.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPRLQDKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            complement(6452..7093)
                     /locus_tag="VLL59_000096"
     CDS             complement(6452..7093)
                     /locus_tag="VLL59_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6508260.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            complement(7086..8090)
                     /locus_tag="VLL59_000097"
     CDS             complement(7086..8090)
                     /locus_tag="VLL59_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6508261.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            complement(8087..8779)
                     /locus_tag="VLL59_000098"
     CDS             complement(8087..8779)
                     /locus_tag="VLL59_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HER6508262.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            complement(8902..10800)
                     /gene="pknB"
                     /locus_tag="VLL59_000099"
     CDS             complement(8902..10800)
                     /gene="pknB"
                     /locus_tag="VLL59_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HER6508263.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIVFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            complement(10797..11537)
                     /locus_tag="VLL59_000100"
     CDS             complement(10797..11537)
                     /locus_tag="VLL59_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HER6508264.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            complement(11575..12897)
                     /gene="rsmB"
                     /locus_tag="VLL59_000101"
     CDS             complement(11575..12897)
                     /gene="rsmB"
                     /locus_tag="VLL59_000101"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HER6508265.1"
                     /translation="MADNWKISIRGKALLTLEHIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLIYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEAAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            complement(12887..13822)
                     /locus_tag="VLL59_000102"
     CDS             complement(12887..13822)
                     /locus_tag="VLL59_000102"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HER6508266.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMELGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSD
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIAAGQGA
                     LSLLVVQPAGKPKMAIADFLNGLGRKLEVGDFIGR"
     gene            complement(13884..16268)
                     /locus_tag="VLL59_000103"
     CDS             complement(13884..16268)
                     /locus_tag="VLL59_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HER6508267.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFVIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKGIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERPIDRSESYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEAKILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            complement(16333..16650)
                     /locus_tag="VLL59_000104"
     CDS             complement(16333..16650)
                     /locus_tag="VLL59_000104"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HER6508268.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(16666..17301)
                     /gene="gmk"
                     /locus_tag="VLL59_000105"
     CDS             complement(16666..17301)
                     /gene="gmk"
                     /locus_tag="VLL59_000105"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HER6508269.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            complement(17411..19018)
                     /locus_tag="VLL59_000106"
     CDS             complement(17411..19018)
                     /locus_tag="VLL59_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HER6508270.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            complement(19148..20044)
                     /locus_tag="VLL59_000107"
     CDS             complement(19148..20044)
                     /locus_tag="VLL59_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HER6508271.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSINIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            20245..21432
                     /locus_tag="VLL59_000108"
     CDS             20245..21432
                     /locus_tag="VLL59_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HER6508272.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            21456..22105
                     /locus_tag="VLL59_000109"
                     /pseudo
     CDS             21456..22105
                     /locus_tag="VLL59_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
     gene            22107..22766
                     /locus_tag="VLL59_000110"
     CDS             22107..22766
                     /locus_tag="VLL59_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HER6508273.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            22799..23578
                     /locus_tag="VLL59_000111"
     CDS             22799..23578
                     /locus_tag="VLL59_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HER6508274.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAK"
     gene            23649..24980
                     /locus_tag="VLL59_000112"
     CDS             23649..24980
                     /locus_tag="VLL59_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HER6508275.1"
                     /translation="MEIIGSLGVLVGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMD
                     PTKTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS"
     gene            25054..25536
                     /locus_tag="VLL59_000113"
     CDS             25054..25536
                     /locus_tag="VLL59_000113"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HER6508276.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(25682..27151)
                     /locus_tag="VLL59_000114"
     CDS             complement(25682..27151)
                     /locus_tag="VLL59_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508277.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALESSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDAVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(27165..28319)
                     /locus_tag="VLL59_000115"
     CDS             complement(27165..28319)
                     /locus_tag="VLL59_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HER6508278.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKINGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            complement(28382..28750)
                     /gene="rnpB"
                     /locus_tag="VLL59_000116"
     ncRNA           complement(28382..28750)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VLL59_000116"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(28764..29090)
                     /gene="gpsB"
                     /locus_tag="VLL59_000117"
     CDS             complement(28764..29090)
                     /gene="gpsB"
                     /locus_tag="VLL59_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HER6508279.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            complement(29212..29727)
                     /locus_tag="VLL59_000118"
     CDS             complement(29212..29727)
                     /locus_tag="VLL59_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HER6508280.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLISYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPMQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            29808..30416
                     /gene="recU"
                     /locus_tag="VLL59_000119"
     CDS             29808..30416
                     /gene="recU"
                     /locus_tag="VLL59_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HER6508281.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            30403..32568
                     /locus_tag="VLL59_000120"
     CDS             30403..32568
                     /locus_tag="VLL59_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HER6508282.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPR
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(33034..34371)
                     /gene="pepC"
                     /locus_tag="VLL59_000121"
     CDS             complement(33034..34371)
                     /gene="pepC"
                     /locus_tag="VLL59_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HER6508283.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNIFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQC"
     gene            complement(34556..35380)
                     /gene="nadE"
                     /locus_tag="VLL59_000122"
     CDS             complement(34556..35380)
                     /gene="nadE"
                     /locus_tag="VLL59_000122"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HER6508284.1"
                     /translation="MTLQEEIIRQLGVKASIDPKEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETSDHAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIASQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKAAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(35382..36836)
                     /locus_tag="VLL59_000123"
     CDS             complement(35382..36836)
                     /locus_tag="VLL59_000123"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HER6508285.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDDSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLAEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMTLIDNIRKDTHGKSE"
     gene            complement(37007..38386)
                     /locus_tag="VLL59_000124"
     CDS             complement(37007..38386)
                     /locus_tag="VLL59_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HER6508286.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(38555..39472)
                     /gene="trxB"
                     /locus_tag="VLL59_000125"
     CDS             complement(38555..39472)
                     /gene="trxB"
                     /locus_tag="VLL59_000125"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HER6508287.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNALIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            complement(39536..39760)
                     /locus_tag="VLL59_000126"
     CDS             complement(39536..39760)
                     /locus_tag="VLL59_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HER6508288.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(39864..40607)
                     /locus_tag="VLL59_000127"
     CDS             complement(39864..40607)
                     /locus_tag="VLL59_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HER6508289.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFTSYSKTYI"
     gene            complement(40607..41410)
                     /locus_tag="VLL59_000128"
     CDS             complement(40607..41410)
                     /locus_tag="VLL59_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HER6508290.1"
                     /translation="MTSVFLTSGWAFYDHLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKCLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(41604..42947)
                     /locus_tag="VLL59_000129"
     CDS             complement(41604..42947)
                     /locus_tag="VLL59_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6508291.1"
                     /translation="MSFKDYHFKQYIQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDETKAEVQVVITAPSRELATQIFDACKQIAKHSQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLVIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGCDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            complement(43105..44115)
                     /locus_tag="VLL59_000130"
     CDS             complement(43105..44115)
                     /locus_tag="VLL59_000130"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HER6508292.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(44117..46372)
                     /locus_tag="VLL59_000131"
     CDS             complement(44117..46372)
                     /locus_tag="VLL59_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HER6508293.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(46376..46699)
                     /gene="ftsL"
                     /locus_tag="VLL59_000132"
     CDS             complement(46376..46699)
                     /gene="ftsL"
                     /locus_tag="VLL59_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HER6508294.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(46704..47717)
                     /gene="rsmH"
                     /locus_tag="VLL59_000133"
     CDS             complement(46704..47717)
                     /gene="rsmH"
                     /locus_tag="VLL59_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HER6508295.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(47948..48172)
                     /locus_tag="VLL59_000134"
     CDS             complement(47948..48172)
                     /locus_tag="VLL59_000134"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508296.1"
                     /translation="MTNEREKEEAKVTLEELLHQIQVIHLELKIVRNWGYFVFFLEMV
                     CWSAGSNVEIMSKVNQLLIDLQVTLQNCRR"
     gene            complement(48192..49442)
                     /locus_tag="VLL59_000135"
     CDS             complement(48192..49442)
                     /locus_tag="VLL59_000135"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HER6508297.1"
                     /translation="MTDMRRLGQRAKKASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     YTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(49435..50256)
                     /gene="proB"
                     /locus_tag="VLL59_000136"
     CDS             complement(49435..50256)
                     /gene="proB"
                     /locus_tag="VLL59_000136"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HER6508298.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGASSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            complement(50320..51948)
                     /locus_tag="VLL59_000137"
     CDS             complement(50320..51948)
                     /locus_tag="VLL59_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508299.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     IKLYIHLPVTSEELYIAKIVSSLGMGTVFLMPLISLLLIVCWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MMDGVFTDYPTIPYFKGFYDVVQAPFATAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNETLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGIMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLMDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGDGQWLTMGLIFGNLIVAGVLGFGAVIIANIIQQ
                     PLLISILLSCLILMVLGLAQLWIQKTFWKSLERL"
     gene            complement(51953..52687)
                     /locus_tag="VLL59_000138"
     CDS             complement(51953..52687)
                     /locus_tag="VLL59_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508300.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            complement(52721..52987)
                     /locus_tag="VLL59_000139"
     CDS             complement(52721..52987)
                     /locus_tag="VLL59_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HER6508301.1"
                     /translation="MEKKRQRLYDVIRHAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            complement(53179..55164)
                     /gene="tkt"
                     /locus_tag="VLL59_000140"
     CDS             complement(53179..55164)
                     /gene="tkt"
                     /locus_tag="VLL59_000140"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HER6508302.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     ANEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHDGTRVYGGTFFVFSNYLLPAVRMAALQS
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEVKLALDT
                     QDKLESEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(55382..56026)
                     /gene="fsa"
                     /locus_tag="VLL59_000141"
     CDS             complement(55382..56026)
                     /gene="fsa"
                     /locus_tag="VLL59_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HER6508303.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(56152..57651)
                     /locus_tag="VLL59_000142"
     CDS             complement(56152..57651)
                     /locus_tag="VLL59_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HER6508304.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNYLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHKHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(57641..58987)
                     /locus_tag="VLL59_000143"
     CDS             complement(57641..58987)
                     /locus_tag="VLL59_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HER6508305.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSIHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDGDLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(59096..59797)
                     /locus_tag="VLL59_000144"
     CDS             complement(59096..59797)
                     /locus_tag="VLL59_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HER6508306.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            complement(59799..61637)
                     /gene="glpO"
                     /locus_tag="VLL59_000145"
     CDS             complement(59799..61637)
                     /gene="glpO"
                     /locus_tag="VLL59_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HER6508307.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQT
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIAPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGHQEG"
     gene            complement(61653..63179)
                     /gene="glpK"
                     /locus_tag="VLL59_000146"
     CDS             complement(61653..63179)
                     /gene="glpK"
                     /locus_tag="VLL59_000146"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HER6508308.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            complement(63539..63931)
                     /locus_tag="VLL59_000147"
     CDS             complement(63539..63931)
                     /locus_tag="VLL59_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HER6508309.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(64058..64315)
                     /locus_tag="VLL59_000148"
     CDS             complement(64058..64315)
                     /locus_tag="VLL59_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HER6508310.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(64469..66508)
                     /locus_tag="VLL59_000149"
     CDS             complement(64469..66508)
                     /locus_tag="VLL59_000149"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HER6508311.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGSFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVARAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDYFGWRIPMDKLVDSLYD
                     LSFDSLTYTNKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAAAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQALKNNRLAILSDLVSKAKTIAAFNQLNTK"
     gene            complement(66886..67803)
                     /gene="glyQ"
                     /locus_tag="VLL59_000150"
     CDS             complement(66886..67803)
                     /gene="glyQ"
                     /locus_tag="VLL59_000150"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HER6508312.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            complement(68175..68708)
                     /locus_tag="VLL59_000151"
     CDS             complement(68175..68708)
                     /locus_tag="VLL59_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HER6508313.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(68840..69679)
                     /locus_tag="VLL59_000152"
     CDS             complement(68840..69679)
                     /locus_tag="VLL59_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HER6508314.1"
                     /translation="MVTIVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            complement(69801..70949)
                     /gene="nagA"
                     /locus_tag="VLL59_000153"
     CDS             complement(69801..70949)
                     /gene="nagA"
                     /locus_tag="VLL59_000153"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HER6508315.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLSLHDGVFGEWTEIVSADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPEREGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPVACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(71067..72698)
                     /locus_tag="VLL59_000154"
     CDS             complement(71067..72698)
                     /locus_tag="VLL59_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HER6508316.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADDKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            72900..73622
                     /locus_tag="VLL59_000155"
     CDS             72900..73622
                     /locus_tag="VLL59_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508317.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(73751..74593)
                     /locus_tag="VLL59_000156"
     CDS             complement(73751..74593)
                     /locus_tag="VLL59_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HER6508318.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYAGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            74886..75443
                     /locus_tag="VLL59_000157"
     CDS             74886..75443
                     /locus_tag="VLL59_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HER6508319.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALVNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEVIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(75479..76303)
                     /locus_tag="VLL59_000158"
     CDS             complement(75479..76303)
                     /locus_tag="VLL59_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HER6508320.1"
                     /translation="MVQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(76305..76922)
                     /locus_tag="VLL59_000159"
     CDS             complement(76305..76922)
                     /locus_tag="VLL59_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HER6508321.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(77119..78096)
                     /gene="lacD"
                     /locus_tag="VLL59_000160"
     CDS             complement(77119..78096)
                     /gene="lacD"
                     /locus_tag="VLL59_000160"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HER6508322.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(78143..78602)
                     /locus_tag="VLL59_000161"
                     /pseudo
     CDS             complement(78143..78602)
                     /locus_tag="VLL59_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(78612..79127)
                     /gene="lacB"
                     /locus_tag="VLL59_000162"
     CDS             complement(78612..79127)
                     /gene="lacB"
                     /locus_tag="VLL59_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HER6508323.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLETHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(79142..79567)
                     /gene="lacA"
                     /locus_tag="VLL59_000163"
     CDS             complement(79142..79567)
                     /gene="lacA"
                     /locus_tag="VLL59_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HER6508324.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(79824..81275)
                     /locus_tag="VLL59_000164"
     CDS             complement(79824..81275)
                     /locus_tag="VLL59_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HER6508325.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYAARNHLPVFVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGPQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            complement(81301..81606)
                     /locus_tag="VLL59_000165"
     CDS             complement(81301..81606)
                     /locus_tag="VLL59_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HER6508326.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIESQMTDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFDLPIPIVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            complement(81599..82072)
                     /locus_tag="VLL59_000166"
     CDS             complement(81599..82072)
                     /locus_tag="VLL59_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HER6508327.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            82309..83079
                     /locus_tag="VLL59_000167"
     CDS             82309..83079
                     /locus_tag="VLL59_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HER6508328.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYNQFTQLLVAHENKE"
     gene            complement(83283..83486)
                     /locus_tag="VLL59_000168"
     CDS             complement(83283..83486)
                     /locus_tag="VLL59_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HER6508329.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLLKRALRDTKFELHKWS"
     gene            complement(83500..85731)
                     /locus_tag="VLL59_000169"
     CDS             complement(83500..85731)
                     /locus_tag="VLL59_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HER6508330.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPSFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGYP
                     NMDSLVALATSFAFAYSLYGVVEISMGQAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATVVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESFPVEKGEKDNVFAGSLNGKGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIATIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLI
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNATLMATLGIDLSCVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(85731..86165)
                     /locus_tag="VLL59_000170"
     CDS             complement(85731..86165)
                     /locus_tag="VLL59_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HER6508331.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNLLTSYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLYDL
                     PMTLEEIEAFQELLEVKKENAVLEVPCNCLPGQCHCQKKETY"
     gene            86337..87323
                     /locus_tag="VLL59_000171"
     CDS             86337..87323
                     /locus_tag="VLL59_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HER6508332.1"
                     /translation="MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGTLVQENLFDMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPET
                     PEYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTP"
     gene            complement(87457..87807)
                     /gene="rbfA"
                     /locus_tag="VLL59_000172"
     CDS             complement(87457..87807)
                     /gene="rbfA"
                     /locus_tag="VLL59_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HER6508333.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRDLDNKS"
     gene            complement(88013..90874)
                     /gene="infB"
                     /locus_tag="VLL59_000173"
     CDS             complement(88013..90874)
                     /gene="infB"
                     /locus_tag="VLL59_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HER6508334.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQIAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNINAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(90894..91196)
                     /locus_tag="VLL59_000174"
     CDS             complement(90894..91196)
                     /locus_tag="VLL59_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HER6508335.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            complement(91189..91485)
                     /locus_tag="VLL59_000175"
     CDS             complement(91189..91485)
                     /locus_tag="VLL59_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HER6508336.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(91501..92658)
                     /gene="nusA"
                     /locus_tag="VLL59_000176"
     CDS             complement(91501..92658)
                     /gene="nusA"
                     /locus_tag="VLL59_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HER6508337.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATAVEEPVVDDVMTAEEV"
     gene            complement(92833..93369)
                     /gene="rimP"
                     /locus_tag="VLL59_000177"
     CDS             complement(92833..93369)
                     /gene="rimP"
                     /locus_tag="VLL59_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HER6508338.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(93477..93563)
                     /locus_tag="VLL59_000178"
     tRNA            complement(93477..93563)
                     /locus_tag="VLL59_000178"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(93527..93529),aa:Ser,seq:gga)
     gene            complement(93628..94263)
                     /gene="trmB"
                     /locus_tag="VLL59_000179"
     CDS             complement(93628..94263)
                     /gene="trmB"
                     /locus_tag="VLL59_000179"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HER6508339.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            complement(94263..95054)
                     /locus_tag="VLL59_000180"
     CDS             complement(94263..95054)
                     /locus_tag="VLL59_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HER6508340.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            complement(95118..96152)
                     /locus_tag="VLL59_000181"
     CDS             complement(95118..96152)
                     /locus_tag="VLL59_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508341.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAILLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNMLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            complement(96155..96880)
                     /locus_tag="VLL59_000182"
     CDS             complement(96155..96880)
                     /locus_tag="VLL59_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508342.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVVLHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            96952..97371
                     /locus_tag="VLL59_000183"
     CDS             96952..97371
                     /locus_tag="VLL59_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HER6508343.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQLATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEKDGISIQYTTHEPNFPVLEKLARQINQEVSS"
     gene            97368..97724
                     /locus_tag="VLL59_000184"
     CDS             97368..97724
                     /locus_tag="VLL59_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HER6508344.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQENSELISS
                     ESPTCQTVILTNNYSR"
     gene            complement(97835..99118)
                     /locus_tag="VLL59_000185"
     CDS             complement(97835..99118)
                     /locus_tag="VLL59_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HER6508345.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     KLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(99127..99651)
                     /locus_tag="VLL59_000186"
     CDS             complement(99127..99651)
                     /locus_tag="VLL59_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HER6508346.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEAIP
                     QELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVTKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            complement(99626..100087)
                     /gene="tsaE"
                     /locus_tag="VLL59_000187"
     CDS             complement(99626..100087)
                     /gene="tsaE"
                     /locus_tag="VLL59_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HER6508347.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDHLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            complement(100241..101701)
                     /locus_tag="VLL59_000188"
     CDS             complement(100241..101701)
                     /locus_tag="VLL59_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HER6508348.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSVSAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSGVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            101965..102777
                     /locus_tag="VLL59_000189"
     CDS             101965..102777
                     /locus_tag="VLL59_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HER6508349.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNINKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
BASE COUNT        31068 a        21820 c        18208 g        31785 t
ORIGIN      
        1 aaatggaaaa agaaaaaaac gcgctttata ttctgaaaac gcgctttttc atattttttg
       61 agaatttcta gcccagaatt ggaactaatc tttttttcaa actaatttta cgtaagattt
      121 acttaaagag gaactgtaat agatactttt gttatataat gactgtcgta tctatcactt
      181 aatctcattt tcatcatgtc acctcgaaac atgaatagct ttttcccact tttaaaatac
      241 gtataatcat ccctgtaggt tttagttgtg aactatttag cttctattaa tcctaggttt
      301 ccatcttcgc gacggtataa aatgtttgtt gcaccatctt cagaatcagt gtagataaag
      361 aaatcatgtc ccaatagttc catctgtaaa cgcgcttctt caacatccat tggttttaat
      421 gtcacatttt tagtacgtac aacttgtact tctggtatct catcgacttc ttcagcttca
      481 aactcagttg taaagacttg accagttgga accttttcgc gatgtttttt agcaattttg
      541 gttttatttt ttctaatttg acgttcgatc ttatcaacaa ctaaatcaat agagccgtac
      601 atatcctgtg aaacatcttc agcacgaagg gttactgaat ctaatgggat cgttacctca
      661 acttttgaag atctctcccg ataaactttt aaattaacac gtgcatctat ttcttggtct
      721 ttagcaaaat atttttcgat tttagtaagc tttgattcta cataatcgcg aatagcttct
      781 gtcacttcga tattttctcc acgaatactg aacttaatca taggatacct ctttctcgcg
      841 cttgaagcgc ttactttatc tttaatacta ttatactgct ttcatgaaaa tttgcaagtt
      901 ttaacgtgca attgacaaac ttttaatgtc actatttgct actttagcca attgttttct
      961 aagagcgata attgtactac cagtagtata aatatcatct actataagga ttttatcagg
     1021 aatgtttgat acttttagta gtcgataaga tttttctatt aataatctct ctttttttgt
     1081 tctggaagat tggtgagtat tatctagctt ttcaaaaaga gaaaggtagc taacattagc
     1141 tgcctcaaga atagcgctca cttgattaaa ttgtctttct cgaaaacaat cgggacttac
     1201 aggaaccggg actgggatat agcctttata gtacttggta ataacatcgg caagttctac
     1261 tgcaaaaact tttcttaata aatagtctcc ttgaaactta tattgactga agtatgcttt
     1321 catagcagca ttataacaat ataagcttct atgatttaca ttgtatcctt tgttttccca
     1381 ttttagacaa tctcgacaag ctattatatc tgagtttgca caacatgtcg cacaaacact
     1441 ttttcctatc ttttgaaagc ttttttgaca ttgttgacaa atcggtgaag agatacgcct
     1501 taaaaagatg atttctgtaa tacttattgg tgtttgacta atttgttgac atagtagaca
     1561 gatcatgcga atacccttta taattcattt ctttaatctc ttttcttgct agtagcattg
     1621 ctttactgat accttcatga aagaaatata acgttccgtc tggtctgtct atagatcttc
     1681 caactcgtcc agcaatttga acaagacttt gggaactata gacacgatga tgagacccaa
     1741 gaacaaaaac atcaatttgg ggaaatgtca cacccctttc taaaattgtt gttgtaatta
     1801 aaatcgtttt tttcccttga cgaaaagctg tgatatcttc tttcctgttt tgtgattgac
     1861 tagaaacaca agctatttgt tcggcgggca ataactcttt taagattgct gtaacagatt
     1921 ctgccattat aatagtgggt agaaaaatta aaaggggata gcctgttttt ctttgttttt
     1981 ttaagtattt taaaatttta ggaggaagtt tttgccgatg tatcatttta aatagattaa
     2041 aacttcttat aaatttcgga ataactaatg gcctattatg aaagcgtctc gccaatgtca
     2101 gcttgactac ttctcccttg tttacctttc tttctaaagt tctagttgaa gttgcagtta
     2161 ataaaatctt tgcgccacct tcttttaaag cctgacttgc agcataatga agttgaatat
     2221 tatttacaaa agggaatgcg tctacttcat caataattaa gagatcaaaa gccttgtgaa
     2281 attttagcag ctgatgcgtt gtggctacta taataggagc tctttgataa ggaagagact
     2341 ctgcgtgcat taaacagatg ctgcaggaga aggcttggga taaacgagta gccacctcta
     2401 cacaaacatc tactcttggg ctggcaatgc aaacccagcc acctgtgtta attaccgcct
     2461 caatcgcagc ataaatcatt tctgtttttc ctgcaccagt tacagcatga actaatgttg
     2521 ttttttgatt ttgcatattg attaataatt gttgggaaat catctcttga taagcagtta
     2581 gttgaccgct ccaaaccaga taattacctt ttggaaaatg cataggtggg atagcataga
     2641 gcaatttatc tgattgattt cgtccaaaga caagacaaaa tcggcaataa taggctccat
     2701 ttggcaatcg tgcttcttca tcaagctgat agtgacaacg ttgacaaatc atttttcctc
     2761 tcgatattac tacacttttt aaaggttgag caagctgctt tgctgaatct ggtaactggc
     2821 tttctagcaa caatcgtcca taactatttt caatagactc catactttat tattcgcttt
     2881 tttttgctaa tttttatctt ttcttgtaca atttttttat ggaacatttt aagacaatca
     2941 aagccagtgg ttttttcgaa gaaagtatta aaaaatctcg tttcatttgt catatcaaac
     3001 gagtaagcac tgaagaagat ggtaagaatt ttgttaatgc tatcaaaaaa gaacattaca
     3061 aagctaatca ttcctgcttt gcgatgatta tcggtaacaa cagtcagatc aagcgctcaa
     3121 gtgatgatgg tgaaccttca ggaactgctg gaatacctat cctttctgtg ttagaaaagc
     3181 agtgtttaac aaatgtagta gttgtggtaa cgcgttactt tggtggtatt aaattaggaa
     3241 caggtgggct aatcagagca tactctaaca tgaccgcaac agctattaaa cgatttggca
     3301 tcattgaagt taaacagcag ataggactag aaatcacact ttcttatccc caataccaac
     3361 tatactctaa cttgctagat caattggctt taaccgaaac agaaactaag ttttcagaca
     3421 cgataaagac aacactttat tgtgatactg aacgtgtgga aaatctcatt gatactttaa
     3481 caaattatta tcatggtcag ataagctgtg agaaaatcgg atccaaagtt attgaattcc
     3541 cctgtgatta atcatcaaca aaagtgatat ggctttatta tcagagtgat agtaaatctg
     3601 tattttactt taataatatc tctccttata cttaaataca cagcgtattt attttgtatc
     3661 aagaaaagag gctaaactat gactaaaatt tacaaaacta taacagaatt agtaggtcaa
     3721 acacctatta tcaaacttaa ctgtttaatt ccaaacgaag ctgctgacgt ttatgtaaaa
     3781 ttagaagctt ttaacccagg atcttctgtt aaagatcgta ttgctttatc gatgattgaa
     3841 gttgctgaag ctgaaggtct gataagtcct ggtgacgtta ttatcgaacc aacaagcggt
     3901 aatacaggta ttggtcttgc atgggtaggt gctgctaaag ggtatcgagt cattattgtt
     3961 atgcccgaaa ctatgagctt ggaaagacga caaatcattc aggcttatgg tgcagagctt
     4021 gtcttaacac ctggagcaga aggtatgaaa ggggctattg caaaagctga aactttagca
     4081 atagaactag gtgcttggat gcctatgcaa tttaataacc ctgccaatcc aagcatccat
     4141 gaaaaaacaa cagctcaaga aattttggaa gcttttaagg agatttcttt agatgcattc
     4201 gtatctggtg ttggtactgg aggaacactt tctggtgttt cacatgtctt gaaaaaagct
     4261 agccctgaaa ctgttatcta tgctgttgaa gctgaagaat ctgctgtctt atctggtcaa
     4321 gagcctggac cacataaaat tcaaggtata tcagctggat ttatcccaaa cacgttagat
     4381 accaaagcct atgaccaaat tatccgtgtt aaatcgaaag atgctttaga aactgctcga
     4441 ctaacaggag ctaaggaagg cttcctgatt gggatttctt ctggagctgc tctttacgcc
     4501 gctattgaag tcgctaaaca attaggaaaa ggcaaacatg tgttaactat tttaccagat
     4561 aatggcgaac gctatttatc gactgaactc tatgatgtac cagtaattaa gacgaaataa
     4621 aaaagggttt ggaactacta aggttccaga ctctttttag tgttcttttt taaaaactgc
     4681 aggctttctt caatccactg aggtaactgc tcttcaagtg gcctaaagcc aatcttgtgc
     4741 cgactgttgg aataacgatg acgatggaaa aaatgctgtt tttcttctgc taaggtccgc
     4801 atagataaac ttggcttttt actatattca tcaatatcaa ttacttgtac taaaacctgg
     4861 ttgcctatag ccaataattg atcaatatcg tcaataaatc ccgtttttat ttctgaaata
     4921 tgaatgagac ctgttgtccc attttcaagg gcaacaaagg ctccgtatgg tttaatccca
     4981 gtgatggtgc catgcagttt gtcgccaatt ttcattagtc aaatacctcg attgtttcaa
     5041 tgataacgtc ttctttaggt ttatcctgtg cgccagtttc aacgccagca atcaaatcca
     5101 aaacttggaa tgaagtttcg tccacaagct gaccaaagac cgtatgacga cgatcaaggt
     5161 gaggagttcc accatttgca gcgtaagaag ctgcaattgg agccggccaa ccaccacgtt
     5221 ctagttcttt tttggcataa ggaatcttac tattttgaac aataaagaac tgactgccgt
     5281 tagtatttgg tcccgcatta gccatcgaca aagccccacg gagattatag agttcatccg
     5341 aaaattcatc ttcaaaactt tcaccataga tggattgtcc acccattcct gttcctgttg
     5401 gatcgccccc ttgaatcata aattcaggaa taatacggtg gaagataatc ccatcatagt
     5461 acccttcttt agccaaacct aagaaattgg ctactgtttt aggagcatga tctgggaaca
     5521 agaccagggt catatcgcca tggtttgttt taatggttgc ttttggtcct ttatggtttg
     5581 gcaaatccaa ttgtggaaac tgtaattctt tgtcaatcaa tcctaattcc tccaaggcat
     5641 ataaaatgcc atcttcttca actttttttg tgataaaatc tgctttatct tgcaaacgtg
     5701 ggtgtgatac tcccattgca atactgatac cagcatagtc aaataactct aggtcattga
     5761 gttcatctcc aaaaaccaaa atgttttcag gttttaatcc taaatggtca actacttttg
     5821 aaacacctag cgcttttgac gtacctttca agacaacatc tgatgagtta tcgtgccatc
     5881 tgaccaaacg aaggtgctct gctaattcag caggcaactg caagccatct cccttgtcct
     5941 cgaaagtcca catctggtaa acatcatgat actcattata atccggacag acctctagtt
     6001 gagcgtagac attatcaata gcattgctaa tcatgtcatt tcgagcggac aacaccgctt
     6061 catgacgacc cgccattcca taaaaaatgc ccatatcatc cgcccatttt ttataggcca
     6121 caacaacatc tgctggaatc ggagcttgga aaataatagt tttagcatcg tctttgacat
     6181 aagctccatt taatttgaca caatagtcag catgtaaatc ttgaacttct tgtggaacac
     6241 cgtaccgagc gcgacctgaa gcaataccaa ccaagatgcc ttttgccttc aaagccttaa
     6301 atactctttg aatcgactca ggcatataac ccgtatcttt gaccctcaag gtatcatcaa
     6361 tatcaaagaa caccattttg atttttttag ctttgtattt tagttttgcg tccatacttt
     6421 cctccaattt gctataccct atattatagc attaattatc gtcttggggg actaaatgat
     6481 gtcgaaaagc atagacaacc gcttgggttc ggtcatcaac ttctaacttg gctagaatat
     6541 tggacacatg tgttttgaca gtttttaagg aaataaagag ttcatcagcg atggtctgat
     6601 tatcataccc tttagctaaa aggtgtaaaa tatcatactc acgcgctgtt agttcctcat
     6661 gcaagtcagg gtgttgatca tgcgccttaa tttttttgtc aacttctgtt tcaatagcta
     6721 actctccctt tgaaaccttg cgaatggcat ttaaaatttc agccgcactc gatgttttta
     6781 acatataacc cttcgctcct gcatcaatga cagggtatat cttttcatta tctagatagg
     6841 aagttaacac aagtacctta gcctctttcc atttttttag aacttctaaa gttgcctcaa
     6901 caccgcctaa ctctggcatc actagatcca taaccaaaac atctggcttc aaagccaatg
     6961 ccaaatcaac cccttcacgt ccattagagg cctcaccaac gacatcaata tcagcttgta
     7021 aattcaaaaa actcttgagt cccatgcgga ccatttcatg atcatcgacc aatatcactt
     7081 ttatcttact catcgtcatc tcccttcact atcggcagtc taatatccat ggaaactcct
     7141 ttgccttttt gactaattaa atgtaggttt cctgctaaat cattgacacg gtcttcaata
     7201 ttcttcagac cataactcaa atcccttacc tgatccatat caaatcctac accatcatca
     7261 atcatcttca attgtaattc tgttgaggtt tgattgagat aaacttcaat tcgactagct
     7321 ttagcatgtt ttaacgtgtt gctaatgaat tcttgggcaa ttctaaaaag attatcttcc
     7381 attgttttag gaagctgagc aatggtttcc ttataaatga cttcaatatc acttttatct
     7441 gttaattcct taagaatcat atgaaggccc tcagataaag tccgattagc tagctcggta
     7501 ggtctaagat gcaaaaggag aatgcgtaga tcattttgag cattttgcaa cattgcttca
     7561 accgttgtta actgtgtttg taattgtgtt ttgtccagtt gttccaaact catcgaaatt
     7621 cctgataaaa tcaatgacga agcgaatagc tcttgactga ctgtgtcatg taaatctctt
     7681 gcaattcgtt tgcgctcttg ttttacaact tcttggctat caagaatata agcactttct
     7741 ttcttttgca tgttagcagt caggtgagac atttttttag aaagtcgact taaattagta
     7801 ttgatttctg atgtctcatc tagatagagt cgtcgattat tgagaatata ttttagattt
     7861 tggttgatgt tacgcttact gttatcatcc ataataatcc acaataacaa caataataaa
     7921 gtcacagaaa ctatcaacaa taaaatcgaa aaccctagac gttcgacctg ccataaatga
     7981 ttgcgaaggt agttaaaagt gattcctaaa ttatccatga ccacaaaaac aatagataaa
     8041 atggtaatgg ttgagtagag ccaaacaaga gcatagtaac gttttttcat cgcctatcca
     8101 cctcaacatt tccggcaata gttgtaacga taattttgac ttttttaagg gattggttat
     8161 ccgtttcttt taacttaata gattcgttgc gcaaatcata ttgctgacat ctaaaaaaat
     8221 caacgcttcc gtatatggaa ctaacatcta aagtaacagt gacatcaata ggtaccaata
     8281 tagtcgtatt tccaaaaatt ttacgtatca caatgatatt atccattcct gtcacaataa
     8341 cattggttaa gtcaaccgtg tcatttcctg agattcgaat gatgttaatg tcatcaaaac
     8401 aataataatc actttcataa ttagcagtac caatccattg atgcttggta ttgttcactt
     8461 caatcttttc ttccttgaaa cgaatcaagg caaagcgatt cttctttttg acttgtgaaa
     8521 aatggttaat gaaaatgtaa actatcccca aaagaacagc catgataatg tagggattaa
     8581 gcatgaaaat taaaaaaaga aacaataaac tgacagttag taaaaaatta ttgcggctat
     8641 cttggttata aaagcgtaat gctaataaga taagaactag aattaggata aaacttgata
     8701 aatcattatc caagattgtc atgataccca tagctagcag tatacactcg ataagtaaaa
     8761 agaattgaaa ttttttcatt agtttcccct tatttctttg tattttatca gaattcctgg
     8821 aaaattgcat ctttatatga cgagtagtta aaaagaatag ttagtggcat gctagtaaaa
     8881 catgagacta actattcttt gttaaggtgt ttgagcagta gtttctgatg ggcttaattc
     8941 agtgttgcta cctggtgcag tactatcatt tgttgaagaa ctgtttgaac ttgacgttga
     9001 actcgatgag ctactagaag agtgtgtttc ttctggataa aggtaaagac taatctctcc
     9061 tttatcagac agactcaaag acgttccata gtaaggagat tgaccactga caatagcttt
     9121 agaactagga gaatgaattg gcacaaagcc cgttgctgag ctagagcttg gcacataagc
     9181 ttttattcta gatgcatcta tacctaaagc tgttaaggta ttgactgcat ctgcataact
     9241 atattctgtt accataggca tagtgatcgt atcactaaca gcaacactga gcgtaatttt
     9301 agactttccg tttggattaa atttatcacc cgcacttggc gattgactga tgactgtatt
     9361 ttcaggatat tcattagtta caatgcgctc aattttgatt tttgattttg gaacaccata
     9421 agtttctatc aaactattca tagcttcttg ataatctagt cctttgtagt tttccatgtc
     9481 aaaacctttg tttccaattg acacataaag cgtaatgctt gagccttgcc tcttagctgt
     9541 tcctgcttta ggatctgttc taactacatt tccctcagca accgtatcac tctcaatttg
     9601 cctgatttta cccactttta gcccaacatc atacagttct tgtttggcaa ctttaagact
     9661 agtgcctgct acattaggaa ctttcacaga agttggttta gttagtataa gataagtaaa
     9721 gagtgctaca cctacaataa agaaagaaaa aagaattttg aataaagtac ctaaaaaacg
     9781 accacttttt ttctttttgg tggggggctg taaagcatct gtttgattag tttgatccaa
     9841 tcgactttcc tgtgttaaca ctgttggggt agggggagac aattttacag aagcggtggg
     9901 acctgaggcc actttgggga ggggtttggt actttcaaca tcctcaaaga caatcttacg
     9961 ctcccgacta cgattataac taagcgccgt cattaagtca cgactcattt caaaggttga
    10021 cccgtaacga tcacttaatt tcttggctgt tgctcgaata acaacattct ccaaagcttg
    10081 tggcacattg tggttctcct cgataataga tggaagaggc ttttgaaaat gttgcaaggc
    10141 aatcgtaaca gcactatcgc catcataagg gatatggcct gtcaacatct caaagagcat
    10201 aatccccatc gcataaatat cactttgaat cgtcgctttg gagccgcgag cctgttctgg
    10261 agacaagtaa tgaacactgc ctaacatcga attagtttgt gtcaagcttg tttctgcaaa
    10321 ggctactgcg atgccgaaat cagttacttt gacaacaccc tccttagtta gtaggatatt
    10381 ttgaggtttt aaatctctgt gtacaattcc tttttggtgg gctaaagtca tagcagaaag
    10441 gacttcttcc ataattctaa ccacttcatt attagataat ggagcatgat tttgaatgta
    10501 tctctttagg tcagcaccat ccacatattc cattactaaa aattgctgtc cgtcttcttc
    10561 acctatatcc cggatggcaa caatattggg atggttcaat tcagccatgg cccgcgcttc
    10621 tcgttggaaa cgcgcaactg ctacctgatc tgtttgataa ttggtacgca agaccttgat
    10681 tgcaacgtct tcattatcca agatcaaatc atttgctaaa taaacatccg ccataccacc
    10741 gcggccaata gatttcagaa tgcgataacg accagcaaat aatttgccaa tctgaatcat
    10801 tcgacgtcct cactttcgtt gtgaaccaaa gcgattgtaa tattatctag gcctcctctt
    10861 aggttagcta agtcaatcat ttcttggttt ttttcatcaa gactaacctt actgcccaag
    10921 atagtcacaa tttcatcatt tgaaatcata ttggttagac catcactgtt aatgacaaga
    10981 taatcccctg gctccaaaac cctcactcct aaatcaggct ctactgggga agcttgacca
    11041 atagattgag tgataatatt tctttgtgga tggctagcag cttcttcttc tgtgatctgt
    11101 cctgccttaa ccaactcatt cactaaagaa tgatcactgg tcaataaggt ataatgccca
    11161 tcatggacaa gaccaatccg tgaatcacca atatgagcat aaatggcgct agattcaact
    11221 aaagctactg cttcaacagt cgttcccatt cctttaaagt cttctgattg gcctagatca
    11281 taaatccgtt gattttctga ctggatagtt tcaaataacc aatctctaat ctgacttaac
    11341 tctgtgaagt ctgtttttac ccattctctt cccaggtctg tgactgtcat ctcactggca
    11401 atatttccag ctctgtggcc acccataccg tctgctaaaa tcactaaagt gatgcctttt
    11461 ttattatcaa acttattgat aaaatcttga ttgtttgagc gtttttgccc aatgtctgtt
    11521 tttaatgaaa tcttcatacg ttttttctga ctcagtcagt ttcctcctaa aatactacaa
    11581 gactcgtctg acttgtccaa taaagaagcc atcagtctgg tattgttctg gtgtgataat
    11641 aagataacca tccttgacaa tatctgcttg tgtatggttc agttttactt gttcaaaatt
    11701 aggatgactt tgtaaaaatg cttcgatgac ttgacgattc tcctcatcaa aaatagtgca
    11761 agtactgtat gttattatac cacctttacg caaggtttga caaacactag acaatatctc
    11821 tagctggata gcctgtagag cattgaaatc ttgactttct ttattatatt tgatatcggg
    11881 ttttcgacga atcaaaccaa ttcctgagca aggagcatcc accaaaatct tatcaaagct
    11941 atccttttca aaatgacgat gaacctctct ggcatctagt tttcttgtct caatgttatc
    12001 agcaactcct aagcggttag cattttcctt caccaactct agtttatgat catagagatc
    12061 taaggcaata actttacctg tttttaagta agatgctata tgagaggtct tgccccctgg
    12121 agcgctacat gcatcaagaa ttatgtcgtc accgtcaatg tttaaagtag gagctacaag
    12181 ctgactgctt tcatcttgaa tagtgatgtc cccatttgtg aaataatcac tggctgcaaa
    12241 atgacctgac gctttggtta aaccagttgc tgataaaagg gaacgttctg catctaaagc
    12301 ctcagcagct tcctctagct tcaaagggtc tgtcacgcga atactagcct tactacgcac
    12361 aaataaactt tccatgatgg ccactgatct gtcagaacca aattggtctt ctaacttttt
    12421 aaccaaccaa acaggcagtg aatacttgac cgaataatac ttatttcgac gcttaattgt
    12481 ttccatatct gggagaggat ggctggtgaa ttgacgtaaa atagcattga caaacttctc
    12541 tgcacctttt ttattgccac gatttttggc aataccaacc gcatcgttaa caatggcatg
    12601 cgctggtaac ttatctaaat aaatcagttg ataaagactg agcataagga gataataaac
    12661 ccatttgtcc aatttatctc ggtctttgac ataatgggct aaataccatt ccaagctaat
    12721 tttacgtgaa acggtaccat atacaatctc agttaataga gctctgtcct tagcagataa
    12781 agctttattg cttagctgct gattaagcgc tatgtttgtg taagccccct gatcaaaaat
    12841 atgttctaag gttagaagtg cttttcctcg aatacttatt ttccaattat ctgccaatga
    12901 aatcacccac ttcaagtttt ctaccaaggc catttaagaa atctgcaata gccattttag
    12961 gtttccccgc aggttgcaca accagcaatg acagggctcc ttgaccagca gctattacca
    13021 aagatttttt ggttttgaca ataacttgtc caggtaatcc ttctccttca gctaattgag
    13081 cttcgtaaat ttttaaacgt tgcccctcta aaaacgtatg cgctaccggc caagggttca
    13141 tacctcgaat atgattgaac acttcttgat cagacattgt ccaatctaat ttttcttgtt
    13201 ctggagagat attaggggaa aaagtagctt ggctgtgatc ttgaggaata ggttttaatt
    13261 ctccagaaag ataagctggc aaactatcca aaagtaagtc tcgaccaatg atggctaatt
    13321 tctcaaaaag agtacctaca ttatcggttt caagaattgg agtgcttgct ttagcgacca
    13381 tgtcacctgc atccatttct tttatcattt ccataatagt aacgccagcc tctttatctc
    13441 cattcataat agcataatgg ataggtgctc cacctcgata tttaggtaac aatgatgcat
    13501 gtacattaat agcaaatgaa actgaatcaa gtaatattgt tggtaaaaat tggccaaatg
    13561 ctgctgtaat aataccatct gcaccaagtt ccataatctc aatgagttct tgagagcctg
    13621 ataatttttc cggctgatag attgatattc catgctcaag agctaattgc tttacaggtg
    13681 ttaccttaat atcttttttg cgtccaacag ctcgatcagg ctgagtaacc actcctaaaa
    13741 tctcataggc aggattatct agcaagccct tcaatacagt tgctgaaaat tggggagttc
    13801 ccataaataa taattttatc atgactttcc tctttgtatt tttattatat cataactgat
    13861 catcctagat ttagtgattt accttataaa aattgttgcg gttcacaatc aataattagt
    13921 tttaaatgac gattatctgc ttcttgactc caatcaagaa tacgattgag cgtctcttct
    13981 aggttatctt caaaacggta ttttaacaaa atttgatagt ggtataaatt gtgtgttcta
    14041 gcaattggct taggagtcgg tcctaatatt ttaatattat ccgataagtg actctttagc
    14101 agttctgtaa cttgataagc tttttttaca accgatgctt ctaaacgatg cgaaagcgta
    14161 atacccactg taaagtagta agggggataa gccatctgac ggcgaatcgc catttcataa
    14221 cggtaaaagg cttcaaaatc ttgtttctta gctaattgaa tagcatagtg atcgggatta
    14281 taagtttgaa tcaagacttc ccctggctta tgggcacggc ctgcccgacc agcaacttgt
    14341 gttaacaatt gaaacgtttt ttctgacgct cgaaaatctg gcaaatttaa ggaggtatct
    14401 gcatttagta ccccaactaa agtcacattt ggaaaatcca gtcctttggc aatcatttgc
    14461 gtccctaaca aaatatctgc ttcctggcga ccaaaactat ctagtatggt tttgtgactt
    14521 cttttttttc gtgtggtgtc aacatccatt ctcaagatct tagcttctgg aataacccct
    14581 tgcaattcat caaaagcttt ttgagttcca gtgccataat agcggatact attgctatga
    14641 cactcaggac aagtaattgg gataggtttt tgaaacccac agtaatggca attcatagtt
    14701 ttagtatcca tgtgaagggt taaagagata tcacagttgg gacatttgtc cacataacca
    14761 cagtcccgac acatcacaaa actagaataa ccacgtctat ttaacattaa gacaacttgt
    14821 tcttttttaa ccaaacgttc tttaatctta tcaatcaaat atggggtaaa attactaact
    14881 gcttgctgtc caatataatc acgaaaatca acaatcgtta cttctggaat cttagcaaga
    14941 gggtttgctc tttgcgttaa ttgaataaaa tgatagaccc ccttactagc ccttgctcgg
    15001 ctttcaatac ttggcgtagc agagcccata accacaactg cttgatggtg tttagctctg
    15061 agcagggcaa cctctctggc atggtatcgt ggattacttt cttgtttgta agttgactca
    15121 tgctcctcat cgataataat tgcaccaata cgttctaacg gggagaaaat agcagagcgg
    15181 gcaccaacca caaccttagc ctgtcctgtt tttatcttgc gccactcatc aaacttttca
    15241 ccatctgata agcctgaatg cataatagcc acttgctttc cgaaacggga aataaaacga
    15301 gaggtcatct gaggagtcaa cgaaatttct ggcactaaaa caatggctgt cttatcctgt
    15361 tttaaaaccg cttcgatgat atgaagataa acttctgtct tacccgaacc tgtaatccct
    15421 tcaatcaaaa aaggtttact cggtttccca atttgttcaa caatttcagt aacagctgac
    15481 gcctgctgtt catttaaggt taaaaaagaa gatggtttga tctggtcaaa ataggactca
    15541 ctgcgatcaa ttggacgttc gtcaatacga attaagtgat ttgtcacaaa gtaagccacc
    15601 acatctctag aaaaggcttg ataaagcgtt gcaagtttag cttccttcgt atgggttagc
    15661 agatagtctt ttaataattg acgctttttg gcacgactag agatgggatg taccgctaag
    15721 gcgtctaagt cgacgtgata atatttttct gtctttaggt ttttcttgtc tttggctaaa
    15781 taactaacag taatatgccc agcttgtatg cccttaagag ctattttttc cttctcgcgg
    15841 tctaaggtag aatataagac agatggtttt ccttcaaaaa gaaagtccct atcaggcttt
    15901 tttagacctg actctggcct tagcacttta tcatagttag agttaagaag attaggaatc
    15961 attgctttta agagcgtgat tttataagaa aaaactgttt ttcgaagctg atcagcaagg
    16021 gtcaattgtt cttggtttag gactggctca ggatctaaaa cggtctgaat cagtttaaga
    16081 gagcttgaat cttcctggcc aaaaccaata acaaagcctt gcaacaaacg attccctttt
    16141 ccaaaaggaa catgcacacg agaaccaagc tgcacgagag aaactaactc ttttggaata
    16201 ccataagaaa atggcttgtc cgtttgcatc aatggaatat ctacaatcac atgagctact
    16261 ttttccattt gcttctcctt ttctgtcatg gacatcgtac taaatatgaa aaaatctaag
    16321 atttctgaaa ccttagattt tttctccttc ttcttctttt tctttggcaa tttgttcttt
    16381 gattttacgt tcctcttcct ctttggccaa gcgttctgcc tcaatcttag cacggacagc
    16441 ttcacgttta gctgaaggat ctgggtgaat cacaacgttt cctgattcaa tttcttcaag
    16501 tgcctgaagt gttgacttca ctgatttaaa ttcttgagtt ggagtggcac cagcttctag
    16561 ttcatgggca cgtttggctt gtaaaatcac aagtgaatac ttggatggta ctttatctaa
    16621 taaggtatca atggaaggtt ttaacatcat aatgtttact cttttctatt tagctttaaa
    16681 gggatttttt gttattttaa tcattttatc ataacgacca atcacgcgct ccacacgaaa
    16741 gtgttctgtc tcaatgatac gcttaacccg ctcagctgcc aaggcaactt catcattaac
    16801 aactgcataa tcgtattcgc gcataagggc aatttcttct tttgctcttt caatacgttg
    16861 agctatgact tcttgactat ctgtaccacg accaaccagg cggtcttcta attcatctaa
    16921 atctggtggt gttaaaaaaa caaaaacacc atctggtact tttgacttaa cctgaagagc
    16981 tccttgaact tcaatttcta aaaagacatc aattccctta tcaagagtct cattaacata
    17041 agttaaaggg gtgccatagt aattaccaac atattcagca tactctagca tttgaccagt
    17101 tttaatgagt tcttcaaatt cttcacgtgt gcggaagaaa taatcaaccc catcaacctc
    17161 gcccggtctt tgcggacgag tcgtcattga aaccgaatat tcaaatttat gatctggcgt
    17221 tgaaaaaatt tcttgtctta ccgttccttt tccgacacct gaagggccag aaaagacgat
    17281 taacaaaccg cgttcagaca ttgtattctc cttattagtt gctttttaat agtttatcaa
    17341 aaaggctagt ctttttcaag aacattttca aaggcaagtc ataaagaaaa agaggataat
    17401 tcctcttttt ctacttggca taatcaaccg ctctcatctc acgaataaca gttactttaa
    17461 tatttcctgg gtaatctaga ttgttttcaa ttttttctct tactttatgc gacaaaatga
    17521 caacctgatc atctgaaatt ttttcaggtt gaaccataat acgaatctca cgtccagctt
    17581 gtagagcaaa actattttgt accccatcaa aacttgtcgc gatttcttct aaatcacgaa
    17641 gacgcttgat gtaattctcc attgactcat tacgagcgcc tggacgagcc gaactgagag
    17701 cgtctgctgc agctactagc acagcgatca cagaatctgg ctccacatct ccgtggtggc
    17761 tagcaatagt gttgacaaca actggatgtt ctttgtattt acgtgcaaat tccattccaa
    17821 tctcaacgtg actaccttca acctcacggt caatagcttt acccatatca tgcaagaaac
    17881 cagcacggcg ggcaagagca acattttcac ctaactcacc agctaaaata ccagctaact
    17941 taccaacctc aacagagtga cgtaggacat tttgaccaaa cgaggtacgg aattgcaggc
    18001 gtcccatgat tttaatcaaa tcaggatgaa ggtttggtgc accaatctca taggctgcag
    18061 cttcaccgta ctcacgaata cgattatcca tttcaagacg atttttctca accaattcct
    18121 cgatacgagc tggatggatg cgaccatcag caatcagaga ttccaaggtc atacgagcaa
    18181 tttcacgtcg aataggatca aatcctgata agataacaac ttcaggagta tcgtcaataa
    18241 taacgtcaat gccagtcaag ctctctaaag tacgaatatt acggccttca cgtccaataa
    18301 ttcggccctt catgttgtcg tctgggagat ggacactggt aatagtttgt tcagtcacat
    18361 actcaccagc aaggcgttgc atggcttgcg ctaacaagtc cttggctgtt ttaactgttc
    18421 ggtccttgat gtcacgttcg gcatctcgaa tgcgcgtcgc aatttcatgg gtcagtttgt
    18481 tttccgtctc cattaaaatc acttcacgcg cttctgcaat cgtcatcgca gcaacttttt
    18541 ccagttctgc ttttttctcc tcttcaagtt tttccacttg aagttgccgc tcatcaatgt
    18601 gtttagattt atcggtcaga ctttgttctt tactatctag taccttttct ttacttgata
    18661 ggttttcatc tttacggtca agagttaagg agcgctccgc taagcgtgtc tcgagttgtt
    18721 taagctcttg tctttcagac ttaaattctt gttcaatctc ttcacgatat tttcttgcct
    18781 cttcttttgc ttctaaaagt aattctttac gatttgcttt actttcacgt ttagctgttt
    18841 ttttaatgtg ttcagcatct acttctgctt tgccacgaat atcaacagct tcttgttcag
    18901 cgtttaaaag agtcaactct gcagcttcct tcgcagactt gagtctaatc gaaataagtg
    18961 cataacctaa tattaaacca atgagggcag aaacaattaa taaaataata ttaaccatgt
    19021 ttgtacctca atatattcta gatttcatta atagaaagcc atctcttagt ttatcataaa
    19081 ttgagcgttt acacaattcc aattcatttt taaaaaaatt aacatttggg ccaagtggtt
    19141 gagaacccta cttaaaaaaa gactgtagca agtcgtccat gatgtaggct tctatttcag
    19201 aataactttt tttccggagg cgtgttaaga caacacgcca agaaatggga cgttccattg
    19261 gaatacactt aatgtccttt aattggtata attctgtaat aggtttggga caaatagtta
    19321 agacgttgtg attaatcttg gtagaattaa gcataaaatc ccaggaagag gacgtcaaaa
    19381 taatattagg tctgacttgg tgacgctcgc aagcttcaag cactaaatgg tgaaccatga
    19441 aactaggatc aaatagggca agttgttcat ctgttaaatc ttcccactga ataacttttt
    19501 tggaagctaa acgatggcgt ggagacaggc atacagataa ttctgatctc tggatttcat
    19561 aagtctcaac caaattatca gcgatgcctg ttggggataa caagactgcg acgtcaacat
    19621 ttcccacgag tagttcattt tttagttggt aagcaccaat ctccttaaca ttgaattgaa
    19681 tccccggatt ttctaaaatc agttttggca ttacttctga gaaaacaact gataaaataa
    19741 gaggaggaat accaatattg atacttccct ttaacccttt actgtgatca tgcaatttca
    19801 aaaacatgtc atcatagaga ctgagaacct tttgagcgtc cttataataa ttatcaccaa
    19861 gataggttaa cccaataata cgacctcttt ttcgtttgaa gagcttaaca ttttcccttt
    19921 tttcaaaatc attgatcatc atgctaagtg tcggctgcga cacatacaac agttccgccg
    19981 cctggctcaa gttaaaatga ttttcaacga ttgcgataaa ataacgaatt tgtttaatat
    20041 ccaaatagga ttctccttgt cttatcaatt gctttttccg gtataattac ctatattatg
    20101 acacaagtag atgttaaatg ctattgccaa ctctatcaaa aaaatttata tgcttataaa
    20161 aattctatat ttttattttt agcgttttct tgttatctta gagacacgga aagcgctttc
    20221 taaaactgaa aggatgttta ttttatgaaa aacatagtta tcgttgaagc tttacgaact
    20281 cctatcggag cttttggagg ctcctttaaa agtgtctctg ctgttgaact tggaacaact
    20341 gtactgaaaa aaatccttga taaaacgcaa gtaaagcctg aaatggttga tgaagtcatc
    20401 ctaggaaacg tccttcatgc aggcctagga caaaatgtgg caagacaagt tgcagtccac
    20461 tcaggaattc ctgaagataa aacagctttc acattagata tggtttgcgg ttctggactt
    20521 aaagcaatcc aattagctgc gcaaagcatc atgcttggtg acgctgatat cgttattgct
    20581 ggtggtgtcg aaaacatgtc acaagcagct tatgtctcaa ctcagcaccg ctttggtcaa
    20641 cgtcttggta atagtcaatt gattgatact cttgttcatg atggcttaac agatgctttt
    20701 aacaattacc acatgggtat tactgctgaa aacgttgctc agaaatatgg catctcaaga
    20761 gaagagcaag atcaatttgc tttagaaagc caagaaaaag ctgctaaagc attagaaaat
    20821 catcgttttg ctgacgaaat tgtccctgtc tctgtgcctc aacgacgcaa agacccttta
    20881 attgttacaa cagatgaata cccaaaagtt gatacaagcc ttgaaaaatt acagcaatta
    20941 cgtcctgctt tcctccctaa agaaggaacc gttactgctg ggaatgcctc aggaataaac
    21001 gatggtgcag ccttattgat gttaatgact gaagaaaaag ctcttgaatt agggttaaca
    21061 cctttagtca ctattgaaag ctatgctagt gcaggtgttg cacctgaact gatgggaact
    21121 ggaccaattc ctgccactca aaaagccctt aagaaagctg gattaacaat ttctgatttg
    21181 gacttagtgg agtccaatga agcatttgca gcacagtcct tggcggtttt aaaagattta
    21241 aagttaaacc cagaaatcgt gaatgttaat ggaggagcca tcgctttagg tcatcctatt
    21301 ggtgccagtg gcgctcgcat tctagtcaca ttaatccacg aaatgaaaaa acgccaagta
    21361 accagaggac tagcaacact ttgcattggt ggaggacaag gaactgctgt tatcgtgaaa
    21421 aacaatactt agtctcgtga aagttggtag aaaaaatgtg taaagaaatc acaataaaag
    21481 aagcggtagc tcacgttaaa gatggtgata ccattatggt tggtggcttc atgacaaatg
    21541 gcacaccaga aaaattaatt gatgcacttg tggaaaaagg tgtcaaagac ctcactttaa
    21601 tctgtaacga tgccggtttt cctgacaaag gcgttggtaa gatggttgcc aataaacagt
    21661 tttcaactat tattgcatca catatcggtc tcaaccgtga agcgggccga caaatgactg
    21721 agggcgagac tgtaattgat cttgtacctc agggaacatt agctgagcgc atccgcagtg
    21781 gcggttttgg gctaggcggt ttcttaacac ctactggaat aggaaccgaa gttgccaaag
    21841 gaaaagaagt cattactatt gacggcaaag acaccttctt gaaaaacctt tgaaagctga
    21901 tgtcgcactt atttttgcta acaaggcaga taaaaatggc aatttgcaat atgcaggttc
    21961 tgaaaataac tttaatcatg tgatggctgc taatgcgaaa accaccattg ttgaagcaag
    22021 agaaattgtt gacgtggggc aaatggatcc taattttgtc catactcctg gcatttttgt
    22081 taactactta gtgaaaggag cctaacatgg gaacatcagc tactgttctt tcaaaagaag
    22141 agattcaaac acgtattgct aagcgcgttg cacaagaatt agaacacaat acactggtca
    22201 acttaggcat aggtttgcca acaaaagtag ccaactatat tcctgaaggt gtaaccatta
    22261 ccctgcagtc cgaaaatggt tttgtcggtc tcactggatt aacagatgat cactacgatc
    22321 ctactattgt taatgctggt gggcaacctg ttagtattgc tcctggaggg gctttcttcg
    22381 atagctcaac ttcctttggt attattcgag gcggccatgt ggccgcaacc gtcttaggtg
    22441 ccttacaagt tgataaagaa gctagcattg ctaattacct gattcctgga aaaatggttc
    22501 ctgggatggg aggggccatg gacttattgg taggtgctaa aaaagtcatt gttgcaatgg
    22561 agcataccaa taaaggcaaa gcaaaaattt tagacaaatg cacccttcct ctgactgctc
    22621 aaaatgttgt taacctaatc attactgaaa tgggagtctt tgaatatcaa gatgaaggtc
    22681 tatgcgccct tgaaattaac ccagattaca cctttgaaga cgtgcaaaac gttaccgaag
    22741 ttaccctaat tgataaaaca aactaaagac taaccaaaag aaagacgagg atagtatcat
    22801 gacacatact aaagaagttg catttatcac tggtgctgca agcggaatcg gaaaacaaat
    22861 cggggaaacc ttattaaaag aaggtaaaac ggttgttttt tctgacatta atcaagaaaa
    22921 actggatcag gttgttgctg actatactaa agaaggctat gacgctttta gtgttgtgtg
    22981 cgatgtcacc aaagaagaag ccatcaatgc tgctattgat acggttgttg aaaaatatgg
    23041 tcgtattgat attttggtta acaacgcagg ccttcaacat gttgccatga ttgaagattt
    23101 tccaactgaa aaatttgaat tcatgattaa aatcatgttg acagcaccat ttattgccat
    23161 taaacgtgct tttcctacaa tgaaagctca aaaacacggt cgtattatta atatggcttc
    23221 tatcaatggt gtcattggtt ttgctggcaa atccgcctac aattcagcta agcacggctt
    23281 gatcggtctg accaaagtaa ctgccttaga agctgctgat tcaggcatta cggtcaatgc
    23341 catttgtcct ggatatgttg acacaccact ggttcgtggc cagtttgaag acctttccaa
    23401 aacaagaggt attccccttg aaaatgttct tgaagaagtg ctatacccac ttgttcctca
    23461 aaaacgcctc attgacgttc aagaaattgc agactatgtg tctttccttg ccagtgataa
    23521 ggcaaaaggt gttacaggtc aagcctgtat cttagacggt ggctacactg ctaaataaat
    23581 ttggagagat aaagaggctg tatcttgtga tctgtctctt tattttctaa taaggaggtc
    23641 ataaaactat ggaaattatt ggttctctgg gggtcttggt aggtgttatt gttattattt
    23701 acctgtctgt caaagaagtt aacattatca tcgctgcgcc tcttgctacc agcttggtca
    23761 ttttgtttaa tcaaatggat ccaaccaaaa ccttacttgg aaaagaaccc aaccaattta
    23821 tgggggcact ctccacttat attctcaatt attttgctat ctttttatta ggttctatct
    23881 tagccaaatt aatggaaaca agcggtgcaa ccacttctat tgcagattat attttaaaaa
    23941 aagttggtca tgatagtcct tataaagtac tcgttgctat ttttctaatc agtgctatat
    24001 taacttacgg gggaatcagc ctctttgttg tcatgtttgc tgtcttgccg cttgcacgaa
    24061 gtctattcaa aaaaatggac ttggcttgga acttaattca agttcctctt tggctcggta
    24121 ttgcaacttt taccatgacg attttacccg gaacacctgc cattcaaaat gttattccta
    24181 ttcaatactt ggacacctca ctaactgctg ccgccattcc gagtatcgtt ggctcaattg
    24241 gctgcgtgac ttttgggctc ttttatatga aatattgtct agcaaaaagt atggcaaggg
    24301 gtgaaactta tgccacttat gcttttgaca atgagataca agtgaaaaca aaaaatctcc
    24361 cacatttcct tgccagtatc ttacctttat tgttgctcat tattatcgcc ctaaccggta
    24421 gccttttcgg aaacgatttt tttaagaaga acattatttt catagcactt ttagctgcca
    24481 ttctcaccgc aagctggctc tttagacagt ttattcctaa taagattgct gtctttaatt
    24541 taggagctag cagctctatt gcacctattt ttgcgacagc atctgcagtt gccttcggag
    24601 ccgttgtgat gattgcccca ggtttcacat tcttctcaga tctcattttg aatattcccg
    24661 gtaatcctct tattagttta gccgtgttga cttcctctat gtcagctatt accggctctt
    24721 cttccggtgc tctaggaatt gtcatgccta actttgccca gtattattta gatcaaggcc
    24781 ttaatcccga aatgattcac cgtgttgcca ctattgcttc taatatcttt accattgtgc
    24841 cccaaagtgg tgtctttctc accttcttag cattgacagg acttaaccac aaaaatgctt
    24901 ttaaagaaac ctttattact gtttctgtaa gtacttttat cgcacaggtc attatgatag
    24961 cctttgatct gttttcttag ccttttctcc tccacaagta gccactttct cactatttgt
    25021 gttatgataa agtgtaaaac aaaggagatt gaaatgacaa aagaagttat cgtcgaaagt
    25081 tttgagctag atcatactat tgtaaaggcc ccttatgttc gtcttatttc tgaagaattt
    25141 ggacccaagg gcgatcgtat tacaaatttt gatgttcgcc tagtgcagcc taaccaaaat
    25201 tctattgaaa cagccggttt gcataccatt gaacacttac ttgccaagct catccgccaa
    25261 cgcattgatg ggatgattga ttgctctcct tttggctgtc gaacaggttt tcaccttatc
    25321 atgtggggaa aacacagttc tactgatatt gccaaggtga ttaaatccag cctagaagaa
    25381 attgcaactg ggattacttg ggaagatgtt cctggaacaa ctcttgaatc ctgtgggaac
    25441 tataaggatc atagcctctt tgccgccaaa gaatgggctc aattgattat tgatcaaggg
    25501 atttcagacg atccttttag tcgccatgtc atctgatact agtgtgttgt caaacataac
    25561 aatcctactg acctatttga cttgttacaa aaaacaagtc tatctgcaga ttttaagaca
    25621 acatacttta ttaatcaaaa aaactgagac aagttgcctt atctcagttt ttttgatttt
    25681 ctcagtaatc taaagcatca gcataacctt tgccatttcc tacaaaataa cccgtcttac
    25741 aattaataga gaacagataa gtgccatcag gcttaaacat attatagtaa ccattgccat
    25801 taataatatt aaccggctct aaaatatatt ggttgcctga aatataacct ctagcttgtg
    25861 aggttgctac aattttttca agaactcctg gattaaatgc ccaagatggg ttagctctgt
    25921 cagcaataac atcttgattg taaggtacac gtgataaatg ccgttgtaag cttgcagggt
    25981 cataacttgt caagccatag ccagatggtg ctactgatgt actttgtcct tgagctgctt
    26041 gagcctgggc tgcttgctca ttagctgctt tagcggcctc agccttgctg gctagttgct
    26101 gacgaccttc tgtgatgctt gcctgcaaga cagcatcaag atttgcattt cctgttgtca
    26161 aggttgcact tgataaatca tcaaaattag catcagcctt gacttcagcc gaaacctttt
    26221 caccatctac aacagcatcg gaaacaaatt taccgttaac cgctgtaata gcagcaatag
    26281 ctttcttaag ggaatcgact tttgctttcg ccttatcata gtaagcagag ctttccaaag
    26341 ctttcaaggc agcttctaaa tctggcaaag tagcaaaggc actatttttt aatttgctct
    26401 ttgtggcatc tgtataaaaa gtaccatatt gtttttcgaa agctttagca gcagccttca
    26461 agcgcgttgc ttttttagca ctgtcggtct gcaaagaggt ctttgtctgt ttacttgctg
    26521 tttgagttgt tttaccactg tcttgtctca agaaatggtt ccaaccaaat acaactgcaa
    26581 gaatggccaa taatagcaga aataaagcta ttaaccaacc ttttttcgtg ttttgtttgg
    26641 ctggatggtg gctatcttca gaaagaaact gatctctttt tggttcttcc ttggtcatct
    26701 gtggttctgg aatgaccctc tctgatggat ctagatctaa cacagggact gtcgcttcca
    26761 ccggaatccc agttaccacc gcagtagtct ccattggagc taagtcttca gctacttctt
    26821 caaccaaagt gctatcttgc tcagcagact ccgcagacac aggttcgtca tcaacaagac
    26881 cggctttact caatgcttct ctttgttttt tgataaaatt atctaaacta gctgtatcaa
    26941 gctctgtata cttagcatca aacttttgag aagaaacttc gtcacggtgt tgcttaatgt
    27001 acttatctaa aatactatca tccttagtaa cacctgcttt tatctctgac tgtttgcgta
    27061 cagcttcacc aattgtcatt gacttggctt cattaagccc caatgtttgc gattcttttg
    27121 ttacttcgac ttctttgctt tcttctgaca cgcttactac ctctctatat cagatgtcgc
    27181 tttacccttt ccccataaaa ttggtacaaa tcaactttta gggtgccgtt ataaagttta
    27241 cgttttttat cagctttttg cccgtatttt agttcaaaaa gttcatcact tgtaaggata
    27301 aatttgctcc atgttttcaa tggtgcaaag gtttgtccca tttcattata caagatgtca
    27361 accgctttgt catcaagcaa ccgttctcca taaggaggat ttgatatcac tacaccatta
    27421 atcttgtctg ttcgaaagtc ttgcagacgc atttgcttaa aggtaatcac atcagataaa
    27481 ccagcttctt cagcattact tttagcaatc tcaatcatgc ggccatcgat atcaaagcca
    27541 gaaatatcta attcgatttc ataattagct tcttgttcag catcatcacg aacttgttgc
    27601 accatgtctt tatctaccca gctccattct tcaaaagcaa acgaacggtt aaatcctgga
    27661 gcaatattca tcccaatcag ggctgcctcg atgcaaaacg ttcccgatcc acaggtggga
    27721 tcaaccagag gtttatctgg aaaccagtta gataaggcca agatagcagc tgccatattt
    27781 tccttgatcg gtgctccacc tttttgaacg cgataccctc gtttaaatag gctagatcct
    27841 gtcgtgtcaa tcataatagt ggcttggtct tttaaaatag atacctcaat gttaaacgtt
    27901 gacccaactt cttgaagagg aactccttcc ggcctgtgga aatgcttttg cagtttctta
    27961 acaacggcct ttttggtaat cgcctgaaca cttggctcgt tatgcaattt agacttaaca
    28021 catttggctt ttgagattgg aaatttagct cctagcggta aataattttc ccaatccaag
    28081 gcaaagacac cttggaataa ttcttcaaag gttctagcag gaaattgtcc tacgataatt
    28141 ttgatacgat ctgctgcacg taaccaaaga tttgttttaa caatcgcttc tacatcacct
    28201 tcaaaataaa ctttcccatt ttcaacctga caatcaaagc ctagtgctct gacttcttta
    28261 ccaacgacag cttctaaacc tgcggctgca gttgcgacta atctaaatgt ttctttcata
    28321 tatctctttc ttttaaatca aataaaagct agcaagtgct agcttaacct attatgcaat
    28381 tttctataag ccatgttttg ttccggaaat aactaggaat tatttccttc gataatcatc
    28441 tgtctaccgt ctgttgacag tcaggatagc ttgttcgttt ccaactatcc catgccccta
    28501 ccaaagtttg ggttgctagc ttgaggggtt taccgcgttc cattttttac gtttccataa
    28561 aaactacgtc actgtggcac tttcagaagt actttggcat atcaaacgac ttagccattt
    28621 ccttcgccgt aatgtgtatg cacatcccta ggcttatgtg ttcgcctagc acaatcacta
    28681 ctggcatcac agccagtgct agcatggact ttcctcatag tattaaaata ctacgcgatt
    28741 atccaaaaat tgcacagttt tcattactca ataatttgtt taccaaaaac ctctttttcc
    28801 aatttactaa tacgtttcaa gatgtcaaaa ttagtagctg attgagcaac acgagtcggt
    28861 tgcggtactg gttgttgaac agtcgctgaa actgtatttc tagcttgaaa cttggccttt
    28921 tttaaggctt cgttctcagc ttttaaagct tcaatttgag cattgaaatt ttcataatct
    28981 ttaattacat tatcaagaaa ttcatcaact tctttcttat caaaccctcg catactagtc
    29041 ttaaattctt gctcaaaaat atctttagga ctataaataa tacttgtcat tctttactct
    29101 ccgaacggtc aatcttttta ccaaaattat atttcagtat tattattaat gatacagaaa
    29161 aatagttcaa aaagcaagta tttaaatacc aataccccta aaaatacaat gctagctttg
    29221 tgacatatca tttagccgat caaaggttag caatagcaac tgataatgcg gcatatcttt
    29281 tgctttcttg agaaaatatt ttaagttggt ctcgttttct gtgtcataaa aaacataagc
    29341 cccttctgtc ttttctaata aaaactgata atattgacta aattgcatcg gttgttcgta
    29401 atttggaaag taatatttta caaagtcaac agccctaaac tgacttaaaa cttcttgatt
    29461 tttttcattc cacctatctc catgcgtttc aaacaagaat atagtagcta tctgcaaggg
    29521 atactcctct tttagctcat tagctacttc caaagcccat tgttcaaaac ccaagttccc
    29581 tgtaaagata aaccaatcca caccattttc caaataactt attaaatctt tacgaatagc
    29641 ctgtttaata attgaaactc gtgggtcttt atggtcaaaa atccctattt caaagcttcg
    29701 gtaacctgta attagaatcg cagtcattag gtgttatcct ttcaaaaaat atgttataat
    29761 aaaagtgctt aaatttttag cattaactag ataatattag gagaacaatg gttaattatc
    29821 ctcataatct tattcgacaa aaagtaagtt ccgttcaaaa gcaaacaaag caaaataagg
    29881 tggacttcgc caatagaggt atgtcctttg aagctgctat caacgcgaca aatgattatt
    29941 atttatctcg tcaaatagct gtcattcaca aaaaacctac tcctgtccaa attgtcaaag
    30001 tggattaccc taaacgcagt cgggcaaaaa tcgttgaagc gtactttaga caagcttcaa
    30061 cgactgacta ttgcggcgtt tataaaggac attatgttga ttttgaagca aaagaaacca
    30121 ggcaaaaaac agctatgccc atgaaaaatt tccatttaca tcagattgaa catatggctt
    30181 gcgttttaca tcaaaaagga atctgctttg tccttcttca cttttccaca ctgaaggaga
    30241 cttactacct acctgctcaa gccttgattt cattttatca gatagataat ggcagtaaat
    30301 cgatgcccat tgattatatc agaaaaaatg gctttaaggt agcatttgga gcctttccac
    30361 aagtccctta tttaaacata attgaacaaa attttttagg cggtgattac aattaaaaat
    30421 ccaaaaatcc ttaagtggct aaagtatgta ttaagtgcaa ttcttagcct tattatcctt
    30481 gttattatta ttggtggtct tttgtttacc ttctacatta gcagtgctcc gagactgtca
    30541 gaagcccagt taaaatcaac aaactctagc ttggtttatg acggtaataa caatctgatt
    30601 gctgatttgg gttctgaaaa gcgtgaaaat gtaacagctg atagtatccc tattaatcta
    30661 gttaatgcta ttacctcaat tgaagataaa cgtttcttta accatcgtgg agtagatctt
    30721 tatcgtattt ttggtgctgc ctttcataac ctaacgagtc agaccactca aggggggtca
    30781 acgcttgatc agcaactcat taaactagcc tatttttcta ctaatgaatc tgatcaaacc
    30841 ttaaaacgta aggctcaaga agtttggctt gctcttcaaa tggagcgaaa atatactaaa
    30901 caagaaatcc tgacttttta catcaacaaa gtatatatgg gtaatggcaa ctatggtatg
    30961 ctgacagccg ctaagtctta ttatggcaag gatcttaagg atttatctta tgcccagcta
    31021 gccctattgg ctggaatccc tcaagctcct agtcaatatg atccttacct tcatcctgaa
    31081 gctgctcaaa atcgccgtaa cgtcgtgttg caacagatgt acatggaaaa acatctgacg
    31141 aaagcagaat atgaaactgc catcgcaact cccgtcgctg aaggtctaca atcactccaa
    31201 cagcgctcaa cttatccaaa atatatggat aattatctaa aacaagttat tgaagaagtc
    31261 aaaaaagaaa caaataaaga tatttttacc gctggtttaa aagtttatac taatattatc
    31321 cccgatgcgc agcagactct ttataatatt tatcattctg gtgattatgt ttactatcca
    31381 gaccaagatt tccaagttgc ttcaacgatt gttgatgtga caaatggtca tgttattgct
    31441 cagcttggcg gacgtaatca agatgaaaat gtttcatttg ggactaacca agctgtttta
    31501 actgatcgtg actggggttc taccatgaag ccaatcacag cctatgctcc tgctattgaa
    31561 tctggtgttt atacttctac tgctcagtcg accaatgact cagtctatta ttggcctgga
    31621 accactaccc aattgtttaa ctgggacctt agatataacg gatggatgac aatccaagct
    31681 gctattatgc tatcgcgaaa tgtcccagca gtccgagcac tggaagccgc aggacttgac
    31741 tatgctcgat ctttcttaag cagtttaggt attaactatc ccgaaatgca ctactcaaac
    31801 gctatctcaa gtaataacag tagctcagat aaaaaatatg gtgcaagtag tgaaaaaatg
    31861 gccgctgcat acgctgcttt tgcaaatggt ggtatttatc ataaaccaag gtatgtcaat
    31921 aaagtggaat ttagtgatgg tacaagtaaa acttttgatg aaaaaggaaa acgtgccatg
    31981 aaagaaacca cggcctatat gatgacagat atgttaaaaa ctgttctcac ttatggtaca
    32041 ggtactgctg ctgccattcc tggtgttgcg caagctggta aaacagggac ttctaactac
    32101 actgatgagg aactagctaa aattggtgaa aaatacggcc tttatccaga ttatgttggt
    32161 acattagcgc cagacgaaaa ctttgttggc tttactaagc gctacgccat ggctgtttgg
    32221 acaggttaca aaaaccgctt gaccccagtc tacggatcaa gtctagagat tgcatctgac
    32281 gtttatcgta gcatgatgac ttacttaaca aatggttaca gtgaagattg gacgatgcca
    32341 aatggtcttt atcgcagtgg tggattcctc tacttaagcg gaacctatgc gagcaacacc
    32401 gactatacta attcggttta caacaatctt tacagcaata acacgacaac agcttctagc
    32461 caaacgactt cagatgatac tagtagtagc aatgatacaa gtaattcaac caatacagac
    32521 aacaatagca atcatccatc taccgatgat aaaaagacaa ctcattaatc tctaactcta
    32581 cttattgtct gtacctacct tttattacat atccatttac ttacttttaa tatctacctt
    32641 aagtgataat ctaaataaaa agcgagtcca cgttctgtga ggactcgctt tttatatgac
    32701 acaaatgact taccacatac aatataaaat aaaaaacaga attctttaat cgtattaaag
    32761 aaaaggtaca acgttaaggg aattagcaac tgatttttca aacgttaacc taaaacaaaa
    32821 tagacttatt taaaattgtt ataaatagca actaatgcca caagagagta tacatgaaaa
    32881 aaacacgttt ccatataccg aagacgtgtt ttttcatatg tcattttctt agcataataa
    32941 tttttttcat gttcactttc ttatgcggag tccaatccgt ttgctgttcg ttttgtccag
    33001 cttttagatt tcatacagtc gcaaagaaag gaattagcat tgtgctaaag cacccattgg
    33061 atcccaagga gctagtactt gtggctcttt ttcataagcc gctaactcgt cagctgttaa
    33121 gaattcttta cggacaacaa tttgataggt atattcatcc atccaagcat ctgaagcaac
    33181 aaagtaacct ttgtcaccaa ccttctcacc ccatgaattt tcaaccttcc attttaatgg
    33241 ttttcctgtt tcatctaagt caacacctgt taaaaccata gcatgtgtca tcaaactttc
    33301 actataatcc aaacgtccag ccttatcttg actaagattg atatccatac tagcttcaaa
    33361 atcgtaagta ttagttgcca aaatgccttt ttgacgatct gaaacttgac ccacatcaga
    33421 accaaaccaa acggactcac cagcctgcat ctgcttgata gctagttctt tgaaacgttt
    33481 catatcaagg ttgaggtagc gaacctcacg actaccgacc acatttccta gcatctcaac
    33541 agtgtatgat ttgccataag gcttatcggc agttggcgca ttaataacag acacataatc
    33601 agaaagcttt aagccaacaa atttgtcgta aaacgcttgc ggtgtcaaac ctttctcaac
    33661 atgatagtgg tcatctttat cacggtaggc aaaatcaaaa tgacgaggtg gtaaaccaag
    33721 ggtcatggcc aagaagttaa aaatttcctg aagaagctct gcttttcgat cctcaacttg
    33781 gtctgcctta gcacctgacg caatcaggtc acgaagaatt tgagcatctt ggcgcaataa
    33841 tttattcaaa tactggttta attcacgact gttacttgat gagattgatt ctgggtaaac
    33901 agattttggc accactccat acttctcaaa caaggaaacc accatgtccc actgaccacc
    33961 atcttgttgt ggaacatcca agagaaactt aactttacga ctggttaatt cttggtcagc
    34021 tgtagcaatg acctgctcca taaaccagtt agctttttca tacttatccc aaaagaaagt
    34081 atgagcttgt gacagttcaa aattttctaa tttaaactct gtgattaatt tgtgtcggaa
    34141 aatgttcaag gcagcaaaca tccagcaacg accagaagcc ttttggttag ataccttatc
    34201 tttagttaaa tcaatagaaa acacaaaatc attgtccact tcactttgac gggtttctaa
    34261 tgattttagc aaaccattat gcgtaacggc attctcaata gctgaaaatt ttgcattggc
    34321 ttcgtaatga gcaaataatt gttctgtaaa tgtctctgtt aatgctgaca ttattgtcct
    34381 cctaaaatat taagataagc ttcacctgaa ataatattgg caagatggtt attatccagc
    34441 cattctattc taaaggatta cttctattat agaccttatt tgattttctt caagaaaaaa
    34501 gttaggataa cctaactttt tttgttttct ttttttactc tttgaacatc atttcttatt
    34561 tccaaaaatc atcaaaaatg gtgattggca ggtgacgctt gtgttgtcct ttatgccacc
    34621 atttttcaat agttgcttga gctgctttgg aaatcagctt cccttccaaa tagtcgtcga
    34681 tgtcttgata ggtcacccct agggcaacct catcagccaa gcctggtttt tgatcttcta
    34741 aatcagcagt tggaactttt tcatacaaag cagcatctgc tcctaaaact ttcaaaagag
    34801 cctttccttg acgtttgtta agcctaaaga ggggaagaat atctgctcca ccatcaccaa
    34861 atttagtaaa gaaaccagtg atgttttctg ccgcatgatc cgttccaata acagcaccag
    34921 ccatttggct agcaatggca tattgactga tcattcgctg acgtgcttta atattacctt
    34981 tgttaaaatc agaaatctca acgcctgctg cttgtagagc ctctacttga ccgtccacag
    35041 ctgccttgat attaatggta agggtctgat ctggtgcaat aaaagccaag gctttttgcg
    35101 catctgcttc atcagcctga accccataag gcaagcgaac agctataaat tggtaagcat
    35161 gatcacttgt ttcctcccgt aactctgcaa tggccatctg ggctagcttt cctgcgaggg
    35221 tagaatcctg acctccagaa atgcctaaga cataagtttt taaaaatgag tgctttcgca
    35281 aataagcttt taaaaaatca acggtttttc gaatttcttc tttcggatca atgctagcct
    35341 tgacgcctaa ttgtcgaatt atctcttctt gtaatgtcat gtcattcact ctttccatga
    35401 gtatctttac gaatgttatc aatcaaggtc atcttgtttt gccacacatc acgggctaag
    35461 tctactgggt agtcttgagg atttaagaca cgcttgtatt catcccaaag cttgtcaaat
    35521 tcttttttag cataagcctt gatttcagct aaggtcggta gctggtaaac taattctccc
    35581 ttgacaaaaa tatcaactaa gagaggaatt gcatcaaaat ttctgacggt tttcttaata
    35641 taggtatagg tcggatggaa catctcaatc tcagttaatt cattaacatt aatatcagta
    35701 aacgtgatat agtcgccttc tgatttgcct ttttcacgac tggtgatgcg ccaaacttgt
    35761 tttttacctg gtgtggatac tttttctgca ttatttgata atttgatcgt atcacgcatg
    35821 ctatcatctt cttgctcaat agagacaatc ttataaacag cacctaaggc aggctgatca
    35881 taggctgtga tcagtttggt cccaacaccc caaacatcaa ttttggcctt ttgcattttt
    35941 aagttgagga tggtattttc atcgaggtca ttagaagcat agatcttagc ctcggtaaaa
    36001 ccagcgtcgt ctaactgctg acgaactgtt tttgagaggt aagccaagtc accagagtcc
    36061 aatcgaacac ctagaaaatt aatcttgtca cccatttctt tggctactcg gatagctgtt
    36121 ggcacaccta ctttaagtgt atcataggtg tcaacaagaa atacacaatc tttatgggtc
    36181 ttagcataag ccatgaaagc atcataatca ttaccatagg cttgcactaa agcatgagca
    36241 tgcgtacctg aaacaggtat atcaaagcgt ttacctgctc tcacattact tgttgcatct
    36301 gctccaccaa tcatcgctgc gcgggttccc caaatcgcag catctagttc ctgtgcacga
    36361 cgggtgccaa attccaaaag gggttcatcc tcaatcacag aacgaatacg agcagccttt
    36421 gtagcaatca aggtctggaa gttaacaatg tttaaaagag ctgtttcgac caactgacac
    36481 tgacctagag ggccttctac ttgcacaatc ggctcattag caaaaaccaa atctccttct
    36541 ttagctgaac ggatggtcaa ttctaatcgt aactctttaa ggtaggtcaa aaagttttct
    36601 ggataaccca gttcttcaag gtaagccaaa tctgtttctg aaaattgaaa ctgctctagg
    36661 tactccacca tgcgctgtaa accggcaaaa acagcataac cattgttaaa aggttccttg
    36721 cggaaataga cttcaaacac cgcatgacga ttatgaatgc cctgctcaaa ataaacttgc
    36781 atcatattaa tctgatacaa atcagtatgg agagttaaac tatcatcttt atacataaag
    36841 gggactcctt tgaattattg ttactattat aacatatttt aaaaaggact ctttggctag
    36901 gatttagaaa taacttgagt tatcgctaaa gtaaaaaaag aactgatcca tcatgacatc
    36961 ctcaaataag aaagagttaa tggattcagt tctatatcgc taattattat ttaaatttga
    37021 cattgctata aatcccaaaa acaataatcc aaatcgttgc tccaatggcg ccgatatagg
    37081 tggattcttg taagaaaaga gagataaaga caaaagcaaa gaaagcaagg gtcaaaggcg
    37141 ttgtcacttt atattttggc atcaaataac catctgccat aaagtcctta gattgacggt
    37201 acttccagtg agcaatcatg gttaaggcgt agatagcaat atatacacct gatgaggagg
    37261 ctgtaatgag tgagaacgca tctgcaactc ctggcaaaat attaatcaaa gctgagatac
    37321 caaccacaac cgctgaagca ataatggcac gacttggcac cccttgtcga gataaagtat
    37381 taatctttaa gcgattggtc aaagcgtttg gagtctcatt agcaatctga tagagatgac
    37441 gaccggttga ataaagggtt gagttaagcg ctgacgctgc tgatgtcaag accacaaagt
    37501 taatcaaggc tgctgcccat ttaataccaa tcaatttgaa caccatcaca aaaggagatt
    37561 catcaactgg taactgatgc catggcacaa ttgccataat agagaccaag gctcccacat
    37621 aaaagatcac aatacgggtt ggaatttctt gaatagcctt tggtagaact tttcttgggt
    37681 tagccgtctc agaagtggta atccccacaa attcgatagc ttgataagca aagaaaacca
    37741 tttggaaggc cataaagaac tttagtttcc catttgggaa catggaaaaa tggtcaaaaa
    37801 tattggaaag gctagcatgg cctgtgtgag tttcaaaacc tgtcaatacc atgaaaatag
    37861 ctgttgcaat caaagctaaa atagctaaaa tcttaatcat ggcaaaccaa aactctgttt
    37921 ccccaaaaac gcgcacagca attaagttga tcgaactaag taagactaag aaaaccaact
    37981 gaatcaacca ggctggccag cttgggaacc aaaattgcac ataagcacct actgctgtga
    38041 tttctgccat tccaataaaa ataagggaaa tccaatagga cagacccgaa aaataacccc
    38101 agcctggacc aatgtatttg gaaataaaat tgataaaggt gtgttgatct ggatcataat
    38161 agagcatttc accgatggca cgcatcatca taaacatgaa ggcacctgta atcatataca
    38221 caaaaataat agatggtcct gttaaggcaa tagagcgtcc tgcccctaaa aagagacctg
    38281 ttccaatcgt tcctgcaatc gcaattaact gcacatgacg attttctaag ccccttacca
    38341 ttccattttc tagttcgtta ttgtctgttt gttcttttat agacattcta aactccattc
    38401 actaaaatac tatttattat atcctttttt cagaaaattt tcaacattta tctaggaaag
    38461 atattaagga aaactgttct ttatatttct taaaggtctt atgcaattta gctttttcca
    38521 gggaaagaca aggaaaaatg aaggagtttt aaccttatga agggaaactt tcaaggtagt
    38581 gataaacacc ttgccctgca attgcaccat ctccaacagc tgtcgtgatt tggcgaaggt
    38641 ctttttgacg aacatctcca atcgcaaaaa taccaggaat acttgtcctc atatgatcat
    38701 ctgtgataat ccaaccttct gaatcggtaa tttctagatc ctttaccata cctgtcacag
    38761 gattcatacc aacatagata aacacacctc caaaagcgtg gtcagtgact tggcctgttt
    38821 tcacattttc gattagggca ttggagacct taatatcatt gccttgaatt tctttgacga
    38881 ctgaatccca gataaagtcg accttatcat tggcaaaagc acgatcttgc agtatttttt
    38941 gagctcttag ttgatcacgg cgatgaacaa cggttacctt tttagcaaac tgagtaagat
    39001 aaatagcttc ttcaactgct gagtcaccac caccaacgac caaaagatcc tggtcacgga
    39061 aaaacgcacc atcacatact gcacaataag aaactcctcg actagtatag tattcttcac
    39121 ctggaacacc tagtacacgg tatttagctc ccgttgcaat aataaccgtt ttagcttcat
    39181 aactagcatc ttcagtcaac acacacttat agtcaccaaa attttctatt ttttgaacaa
    39241 taccataaat gttttcaacg ttaaacttct ctaaaggttc gtacattttc atagctaatt
    39301 ctggtccaga tatatgatca tatcccgggt aattctctat atcaaaagtg ttgttcatct
    39361 gaccaccagg tgccccttgt tcaataatgg caacagataa attacttcta gcagcgtata
    39421 aagcggcagt cattcctgct ggtcctgaac caataattaa tgtatcgtac atgatttttc
    39481 tcctttaatc tactcttgcc aatattttag caatgataat cccttcttgc aatgattagg
    39541 attttatgac aaccaaaata ctcataaaag caaacgataa aattgggatg gttaaaatag
    39601 caaccattag catctcataa agaaaagctt gtctttcaat caatgtttta tctcttttgg
    39661 tttttgctcg ccataaagtc catattaaac aaattaaaat catagtaagg cttgagagaa
    39721 tgagaccttt tacataaagg ctaaagattt ctactaacat atttccacct agtcattatt
    39781 tctttcccat aagtttttct aaaaaacata acaagaaaag cccaggaata cctagacctt
    39841 tttattataa caaaagaata acattaaatg tatgtttttg aatagcttgt aaaaaattct
    39901 ttggttcgtt ctttttgagg atgtctaaag acttcttcag gtgttccttg ttccaagatt
    39961 ttcccttgat ctaaaaagag tactctatct gccacttggt aaacaaaatt catgtcgtga
    40021 ctcactaaaa ccatggtctg tccggattta gcagcatcag taatagactt ttccacttcg
    40081 ccaactaatt ccgggtcaag agccgaggtc ggctcatcta gtaataaaac atctggtttc
    40141 atagccagag ctcttgctaa agctacccgt tgtttttgtc cccctgataa atgacgtggg
    40201 taatgatgtt ttcgatctgc taaaccaacc ttagccaatt ctgcttgcgc cagtttagtc
    40261 gcttcttggt cagacagttt tttgaccacc ttaagacctt ctttgacatt ctcaagggct
    40321 gtacgacgct caaaaagatt aaattgttga aaaaccatgg caagtttccg acgtaaaata
    40381 aggacttgct ctgtggtaat ggtctcaaaa tcaaccgtaa agtcaccaat gctaatggag
    40441 cctgaatctg gtttttccaa atagtttagg ctacgaagga aggtcgattt ccctgctcct
    40501 gaagcaccaa ctaaagcaat cacttgacct ttttcaatat caagagccaa actatctaaa
    40561 actttttgcc ctgagaatgt cttgctcaaa tttctaattg taatcatcaa cgcaattctc
    40621 ctaacttttc atttctagct tgttctggtg ctttgatggc catcttgttt tcaatcaaac
    40681 gacctacttg ctccatcaaa atactgatag accaatagac aagagcaaca gagatataac
    40741 gttcaaaata acggtaatct gatccgccta gaatttgagc ctgagcaaac atttcgacaa
    40801 tccctgcatt aaaggcaagc gatgttcctt tagttaagcc aattaaccca ttaatcaagg
    40861 ttggaatagc cacaacagtt gcattaggaa taatgacacg acggtaaacc tgcacagaag
    40921 tcatgcctag actttttgct gcttcaattt cacctgtatc tactgataaa atggctgccc
    40981 gaatagtttc actagcgtag gctgcttcat taaaagcaaa ggctgtaatg gcaaaaatag
    41041 aagccggaat tgcattaaca ttccaatcaa agccatactt ctgattgaga cattttagaa
    41101 agaggggaat accgtagtag gtcaacatca actgtaccaa aataggagtt cctcgcaaga
    41161 aactcacaaa aatagcttga atagggtata gtagcttcac tttattaatt ttgacaaggg
    41221 caaaaatcaa agccaaaacc aagccaaagg ttgctcctga tagtgtcaaa ccaagcgtaa
    41281 ttggaagccg ttggataata tttggaatgg catcaaaaac agcatgccaa ctaaaaagtt
    41341 tcccatgtgg aatcggtgag atgagatgat cataaaaagc ccaaccactg gttaaaaaca
    41401 ctgatgtcat gtatttcccc tttgtatttg tttgtcttaa tattctaaca ctcttagatc
    41461 cacatgtaaa atagtaaatc cgtattatag caataagcaa aagctatgat cactttttgt
    41521 gttaacaaat ggtaaacaat acaagtagca ggtgtaaaaa agcaagatta gatgccaatt
    41581 gatcacttgc ttgctctttg ttcttaaaaa tgttgttttt tggccttacg ctcagcgcgg
    41641 cccttagcac gattttcagc acgacgttct ttgcgacgtt tttcatcaac cgcccactga
    41701 atttttttct tgtaacctgg tttgactttt ttctttttct ttttgaccaa accaatcatt
    41761 tctgtgtcta atttttgata ggctttttca cggttttgac gacgatcacg gtcataggta
    41821 tcttgaaatt ctccattttt gagcaccttc ggtgtaaagg caatccccat tttttccagc
    41881 tctttgatat ctgagtcgtc acttggctgg taaagtgtaa tggcagttcc tgccatacca
    41941 tttcgacctg ttcggcctac acgatggaca aagaaagaca agtcttgtgg gatggcgtca
    42001 ttgatcacat ggctgacccc ttcaatgtca atcccacgcg ctgctaagtc tgtggcaaca
    42061 atgtattcaa agtccagttt tttgacttgg ttcatgatgc gcttacgttc tcttggagga
    42121 atgcccccat gaatcttagc cacttttaag ccattagctg ttaaaaaggc atgcaaatca
    42181 tctgcgcgtt ccttggtatt gacaaaaagc atagccatat aaggctgcat ggttttgaga
    42241 atctctaaca gttgaccatt cttatcacac ccttttgtcg acacaagcca gttatcaatg
    42301 gtatctgcga taacggtctt tgtcttgatt tgttcaataa caggattggt caagtatttt
    42361 ttcaaaaagg gttgtaattt ctgtggaata gttgctgaga acaccaaaat ctgaacagat
    42421 tttggaagcg aagctgcaat cttatctacc gtatccaaaa agcccatgtc catggtcata
    42481 tcggcctcat ctacaacaaa ggtcgttgct ttatgaatca ctaaatcacc agacttgacc
    42541 aagtcataaa tacgacctgg ggtcccgatg acaatatgcg gctggctgcc ttttagtttt
    42601 tcaatctgac ggagtttgtc tgtgcctcca acatagttgg ccaaacgaat ctcttcttgg
    42661 gagtgcttag caatctgttt acaagcatca aaaatttgag ttgctaattc acggcttggt
    42721 gctgtaataa cgacttgcac ttctgcttta gtttcatcaa gtttttcaaa aatgggcaac
    42781 aaaaaggtgt gggttttccc tgaacctgtt tttgattccc caactaagtc acgaccggag
    42841 ttaacaatag gaatcagccg cttctggacc tctgttggat tgacaaaacc aatttcttcc
    42901 agtgcttgct ggatgtattg cttaaaatga taatctttaa atgacatgtt ttacctcgtt
    42961 ttcttccata ttatatcatt attgttagag acaagcaaaa ggagtgggac aacactcaca
    43021 aaatcagcat ttgtgggtca tctccactct cttattgatg atgttaatca aaatgctatt
    43081 ggtgactatt cttgataatt ccccttagaa gacgtataag atagctaaaa ctagtaaact
    43141 agctagactt cctactcccc acaaaaaagc atctacctgc cattctgacc acttcttgcc
    43201 tttaccagac aagcctccca attccaaatg gtggtggaaa ggcgtcattc taaaaatacg
    43261 acgaccttct ccatattttt tcttggtgta cttgaaatag gacacttgca acatcacaga
    43321 acttgtttca agaacataaa cgatcccaat aatcaagaga gtccattctt gacgaagcgc
    43381 aatagaaatg gcagccaaca tagctccaag ggctaaacta cctacatctc ccataaatac
    43441 tttagcaggt ttgtgattaa aacagaagaa gccaagcaag gctccaatca ttgctccaat
    43501 cagtaacaaa acatcaaatt gactctgaac gtaggcaata acgccgtaag tcactagact
    43561 aatcaccact gagatagaag ctaagccatc gataccatct gtcaaattaa cggcatttga
    43621 aaaaccaacc acccaaaaca aaacaaagaa taggtagaaa attcccagcg gcagctgata
    43681 accaaacaca ttaatagagg aaatgccact tggactaaca tgtaaaaaat agaacatcaa
    43741 tcctccaacc aactgcaagg ctaacttttg tttggctgtc aatccttcat tgatttgctt
    43801 aaaaattttt aaaaaatcat ccaaaaatcc gataatcccg taaatgacaa caattgataa
    43861 aatgcctgaa atcaaagcta aactttgagt gtttttgatc gaaaatagac taaccaataa
    43921 cgatactgcc gtagctacta aaagaaaaac agttcccccc atagtcggtg ttccagcttt
    43981 agctaaatgt tgcttgacat cttcatgcat ttgttgccca ccaatttttt tcaattgata
    44041 gaatttgata aaataaggca ttgtgaaagc agataccata aaggatatga ttgctgcaat
    44101 aagggttaaa aacatgttaa tctcctaaag taatggtcat tttttttatt tttttcaagg
    44161 atttaccaac atcaacactt tgtttcataa cacgaccaga atctgttcct ttaaagctga
    44221 tgtctattcc agtccattta gcaaaggttt taacattgga ttttgtccag ccatacatgt
    44281 ctggtacctc cacaaaacgg tctgataata tgagaacttg ttggttttct gttaacgttt
    44341 gaccgggctg atgcgatact tttttgatct tgctgccagt accaaggaca actggctgga
    44401 caagatttcg acgcaactcg cttgatgtct caccaggatt ctttcctaca aagtttggta
    44461 atttataagt tgtttgacga ttagcatctg atactactgg cttagttagt gtatcttgca
    44521 ttaagtatgc ttcttccaat actgggttaa ccacatcttg ccaaaaaagg ggaccaaaat
    44581 gttgtggttt agtcatagta acatacatca aaaagtctgg tttatcagct ggcaccattg
    44641 ccacaaccga atagacatag ttagtcaatc caccatcttg ataaccactt ccatcttctg
    44701 aaccaatttg tgctgttcct gatttaacag caacaggtaa atcacccact ttaataattg
    44761 gtccaaatgt ttttgaatag agtgttccaa actcagggtc tgttcctaca ccaatcatgt
    44821 attgtcttgt ttcactagcg gctttttttg atacaggttt tccaacaatt tctttatttg
    44881 ccgttctaaa acttgctgtg ttaggatcat aaatttgact gataaattgt ggctctaaca
    44941 tctcaccatt attagaaata gcagtaaagg ctctaagcat ttgaatctgg gttacagaaa
    45001 tcccttgacc aaaagcgctc atagcttgag tcacgatatt atcagaagga aatatacctg
    45061 cgtcttcatc ttttaaacca aaacgagtag gaaaaccaaa gcggaacttc gtcaaataat
    45121 tcatccattt tgcattaccc attttttgtt caagtttagt catcccaacg ttacttgaga
    45181 aggcaaaccc ttgtgcataa ttcatgtact gtcctgtgga aatgccttcg ttaatagacc
    45241 agtcttgaat agtagcatct gcaattgtta aaccattagc attgctaaag gtttcgtttg
    45301 ggttgaaaac tttatcatca atagccgctg ccagagtcat cactttcatg gttgagcctg
    45361 gctcaaaatt tccttgatga agtgcactgt accatttgta gttcgtattt tcaagtcctt
    45421 tcagagtatc agcattataa gtggggcgtt gtgttgttgc caaaatttca ccagttttag
    45481 cattaacaag tgttgcactg gccaactgac catttgattt ggcttgaaaa acatccatct
    45541 gggtttctaa gaaggtctgg ataggctcag atagcgttgt gtaaatatct ttgccatcaa
    45601 tagctttctt gacagtctta cctgtaccca agagtgtggt cccatttcga tctttttgat
    45661 aagtaataac accatcttga cctgataaaa ttttatcaaa agaagcttct agacctgttt
    45721 ttccaactaa actcttaaca cctgtctttt tatcttctgt tagagatgct aggcctataa
    45781 attctgaagc aaatgtccca tttggataca tacgaccagg actagttgtg aaagcaattc
    45841 ccttgatttt ggcatcttcc atagcctttt gaatagtaga catagtacta tatgaaatgc
    45901 cagaccctga cggtccaaac gagacttgga aaagtccttt acgcttaagc tgtttaatta
    45961 catctgtttt tttcattccc agatgctttt ttaaaatatc agctactgtt tcatactgag
    46021 aaggttgtac atataacttt tcatctgaag ccgagacaaa tgatttatcc aaaattgcgt
    46081 atatgctata agtcgtagaa tccactgcaa tagctgtacc atttcgatca taaatggtcc
    46141 cacgcttagc ttggatcgta acggtttctt gataaacctt cttcgcccct tctgacaaac
    46201 taactccaaa cttttgatct gttccaataa taatcatgaa attaataatg aaaataaaga
    46261 aaataaagat agttaagagc atcatatttt gtccaactcg aacgcgattt tcgactggag
    46321 ttctcctatc gcgcacaaca taatctaaaa catatttttg ccattttttc atagattact
    46381 cgactttctt gatattatta ttacggttgc ttaagcctgc tttaccagca atatctataa
    46441 tacgatcacg gcgagataac tcatttactt cttgcttggc attattaagc tctagttttt
    46501 gatccgaaat atgactattt aaactagtga tttcttgttg tagctgcaac ttacgacttt
    46561 gcaggtaaat aatacttact gccatcgtaa tcgctgttac aatgatagca gtataaaaag
    46621 ccttctcaat tctagagaaa gtttttattc gtttttgcaa ggcatttgta actgcctgag
    46681 ttcttttttc atttgtcata ggcttatttc cgaatttttt tggcaacacg tagcttggct
    46741 gagtgtgccc ttttattagc tgttaactct gaatgactag gtaagatcgg cttacgtgaa
    46801 acaagttcaa acttaggttt catatcttca ggaattagag gaagcccttt tggcacatcc
    46861 accgtactag cttctttaaa caactgcttg gttaggcgat cttccagaga atggaaggta
    46921 ataactgaga tacgaccatc aagggctaat aattccatag cgtcctgaat agattcatcg
    46981 gccgctccca attcatcatt gacttcaatg cgaatagctt gaaaaatctg tttagcaggg
    47041 tggccttttt tcttcaactc tttagctggc tttgctgcct taatcaattc tgccaactct
    47101 gttgttgtct caataggctt aatagctctt gcttgttcaa tttttcgagc gatctgcttg
    47161 gagaatttat cttcaccata tttgaaaaaa atcttaacca aatcattgaa tggataggta
    47221 ttcaccactt cgtaagctgt taagagcgac tgacgatcca tgcgcatatc caatggagca
    47281 tcttgtttat aagaaaaccc tcgttctctt tcatccaatt gcgggctgga aacaccaagg
    47341 tcgtataaga taccatcaat ttcatcaact ccaagcgctg ttaaacgtgc tttgaggtgt
    47401 ctaaaattat ctttaataaa agttacctgt cctttgtcaa tataagattt gagggtaact
    47461 tgtgcattgt caatagcctt ttggtcttgg tcaaaacaat agaggtgccc ttcttcacca
    47521 agtttggaca acaaataagc tgagtggcct gagccaccta gcgtcgcatc aacataaatc
    47581 ccatcaggct ttatgtcaag catgtccact gtttcgtgaa ggagtacggt cacgtgatga
    47641 aattcttttg tcataacttt aattgtacca tacttcaaaa ggtttagaaa tgaaaaagta
    47701 agagaaaagg atttcattct cgtgggaatc ttcctcttct ctaatcttgt tctttttgtt
    47761 cgctatcagc caacttagca agcactgact tagccactgc ctctagagtt tcaactgctt
    47821 gtaaaagatt tttagcttcc ttaatcacac aacaatctgt cagcgggttg tctaaccaaa
    47881 taccaaaggt tttatcccaa ctcgtatttg gtaagtcagc taataatagc ctatcgacgt
    47941 ctgccagcta tcttcggcag ttttgaagag taacttgtaa gtctattaat aattggttga
    48001 ccttgctcat tatttcgacg tttgatccag ctgaccagca taccatctcc aaaaaaaaaa
    48061 caaaatagcc ccaatttcgg acaattttca attccaaatg aatcacctga atctgatgta
    48121 aaagttcttc taaagtaacc tttgcttctt ctttttctct ttcattagtc attaagggac
    48181 cttctagtag cttattctct gatatgtcca tctccattaa tataaaattt agtgctggtc
    48241 aaggcttcta agcccattgg cccacgggcg tgcatttttt gagtagaaat cccaatttca
    48301 gcaccaagcc caaaaacaaa accatcggta aatcgtgttg acgcgttgac ataaacagca
    48361 gcagcatcca ctaaatcttg aaaggtctct gctgccttaa tatcccttgt gatgatagct
    48421 tcggaatggt gactagtata ctgatttatc caagaaatag cttcttccaa agaggaaaca
    48481 accttaacag acatgatata atctaaaaat tcggtctcaa aatcctctgc ttttgcaggc
    48541 actgcctgct caaataacgg caaagccttg tcatctgccc gccattctac tggctgaacc
    48601 tgattgatcg ctttttcaag cataggaata aaccttgctg ctacagcttc gtgaattacc
    48661 aatccctcag ctgcattgca aacacttggg cgctttgttt tagcgttgat aacaatctta
    48721 gtagccatat ctaagtcagc ttgagcatcc acatagatat gcacattccc cacacctgtt
    48781 tcgatgacag gcacttttgc tttttcctta acggtctgaa ttaatttagc accaccacgt
    48841 ggaatcaaaa catctacata atccgttgcc tgcatcaatt cttcagcgac agcatgtgag
    48901 ggatcctcaa ctagctggac agcatctggg gtgatccctg atttttccag actttgtcgg
    48961 atcaacttca ccaaagcttt atttgagtga agggcatctt ttcctcccct taggatgatg
    49021 gcattattgg ttttgaacgc cagactaaaa gcatccactg aaacattcgg gcgactctca
    49081 aaaatcatcg caatcacccc tagaggaact ctcttttgga ggattttaag gccatcgagg
    49141 ttagtatagc ccttaatgac ttgtccgatt ggatcagcta agtcagcaac ctgttgaact
    49201 ccctgtgcta tcgctttaat ccgttctgaa gttaagcgca agcgatccat catgatgtca
    49261 gaaataccat gttctttagc attcgctaaa tctttttggt tagcggctaa gagagtctgt
    49321 gtatcgtcaa ctaatgcctt tgctaaggtg cttaaaaagc gatttttaat ttgcgtcgac
    49381 aaaggtgcta ttaaaagact agcttttttt gccctttgcc ctaaccttct catatcagtc
    49441 atgtgttacc tcttctatct gcttgaacca ggtgcctagt ggttgccctt caagcactct
    49501 taaaatatct ctgggattag ctccattcat caagaccatc tgtcctttgt tttcaaatac
    49561 catctgagca gactgaattt tgctaagcat cccacctgtg ccaaatttac tgctcgcacc
    49621 acctgctgac gcaatgattt cttgcgtaat gactgcaaca tggctgcgta gctgcgcatc
    49681 ctcataaata gtagggtttt tatcaaaaag gccatcaata tcagacaaca tgattaataa
    49741 atcagctttt gtaataccag caacaacagc agataaacgg tcattatctc caaatttagt
    49801 cgcatgatcc atttcatcca cactaaccgc atcgttttca ttaacaatcg gcacaatacc
    49861 caaactaatc agactttcaa aagcattggt aacattggct agactttctg ggaaaaccac
    49921 cacatctctc gtcaataaaa tttgtgacac gttggtttgg tagtgtgcaa aaatttgtga
    49981 ataaagactc atcatggcta cctgaccaac actggaaact gcctgttgtt tagcaagatt
    50041 ggtcggacgt ttttccattt tcaaaatatc tagtccaaat cccatcgctc ccgatgatac
    50101 taaaataact tccttgccct tattcatcaa acttgaaatc acaaaagcca gttggtcgat
    50161 tttttctaaa ttgattttac ctgttggtag cactaatgaa ctagtgccaa ttttaattac
    50221 gatacgtgtt acatcttcaa attgtcgttt catcataccc aaattatagc ataaaaacag
    50281 ccccagagga ctgtttttcc taataatgac ctctcttcgt taaagcctct ctaagctttt
    50341 ccagaaggtt ttttgaatcc ataattgcgc aagacctaaa accattagta ttagacaact
    50401 caatagaata ctaatcaaca gaggttgttg gatgatattg gcaatgataa cagctccaaa
    50461 acctagcaca cctgcaacta ttaaattacc aaagataagt cccattgtta accattgccc
    50521 atctcctctg gtaaagagtt gcgtcatgtc ttgccatttt aaatccagaa gccggtagtc
    50581 acgacgatac atcaattccc cttgcacaat cagtgatagg gcgtagccaa gacaaaaagc
    50641 aatcgttaga agaggatgca ggtgcaacac aaagagacca aacacaagat aaatcaccat
    50701 aggcacaatc agttgcagac ctacaagcaa gcaaaattta tccatcaaga atttttttaa
    50761 cgttattggt aagcttttaa taaaggtaaa gttatccttt tcaagtgaaa tacctactcc
    50821 aataaagctg gttggtgttg cacacatgat acccaaacta accccaaata ataaggccac
    50881 cccaaagtaa tctggggaaa tatgcttaaa gaaacctgtg ccacgtgaca aacttggacc
    50941 gataaaaagc atcacataca tcagaggcat gagataggtt tgtgtcagta aagtttcatt
    51001 ttgtaacgtt aataggtgat gttttcgcaa caactgcgcc agtgattgat tctgatgagg
    51061 acgattaact ggttttttag tttgcttggc tttgttctcg ttactaatat aaaaagcctc
    51121 acgataataa gttggcatca cttttgtgac aataccatat accatagcta gaataagtaa
    51181 caatggcaac caaaagttaa ggagggccgc agtagcaaac ggtgcctgaa caacatcata
    51241 gaatcctttg aaatagggaa tagttgggta atcagtaaat acgccatcca tcatcgtacg
    51301 cttgttgtta ctaatattaa tcgcaaaaat taagacgaaa gcgccaaaag ttgagacaaa
    51361 catcatgata gttgaaatga gttttcgttt gcgacttctt acaatgattt tgcctaccca
    51421 agcattgata taaatagcta ataccataga actcactagt aacactaaaa agagcacgat
    51481 agctactaaa atagacaaag gatttcccaa gagttgccaa cagacaatta agagaagaga
    51541 gataaggggc atcaaaaaga cagtacccat ccctagcgat gagacaattt ttgcaatata
    51601 gagttcttct gacgttactg gtaagtgaat ataaagtttt atgtcattac tttcataaaa
    51661 aatggtgtaa agagagctaa aggctgtcaa ggttgacatg ataaaaaaca tagcaacatc
    51721 aaaggagaaa agtcctggat aatgactgaa atcaacacca ataaacataa aaaggtaaat
    51781 caccaaaaac atggcaatca ttaaagcctg ttgcctcatc atgcttttat aggccttgaa
    51841 gttttctttc gggtgttttt cctgacgctt tttgaggtta gctaaacttt gcggattgga
    51901 ataaagaatg tttatcttga taagttccca aatagtagac caattcatgc catcacccct
    51961 cttcttgcgc cttacgacct gcaagttcaa ggtagatgct ctccaagtct ttgtcaggat
    52021 ggtgttcttt taactcatca atcgttccaa caaaaatcaa tttccctttt tttagaatcc
    52081 cgatacgatc acataactgc tcagcgactg atagcacgtg agtcgaaaat aagaccgtat
    52141 gtccagaagc tgcatgagct ttcatcattt ccttaaggtc aaaagaagcc tgaggatcca
    52201 aacctgttaa tggttcatcc aaaatccaga tgttaggatt tgatacaaga gcaccaatca
    52261 caatcacttt ttggcgcatc ccatgtgaga aactatcaat ggtttgatta acttcttcct
    52321 tcagttcaaa aagtgttgtc agctgtgcta accgttcttc tcggtcctca tctgacaccc
    52381 cataaatttt agctaaaaac tgccaatact catttggagt tagattcaag aaaatatcag
    52441 gagaatctgg cacataagca atttgttttt tgatagcttc tctattttct gtcagaagtt
    52501 gaccatccac aaatacttcg ccataactcg cttcgataat agaagtcaaa atgctgatgg
    52561 tcgtggtttt accagcacca ttatgtccga taaggccaaa aatttcaccg tcattgatgg
    52621 tgacgtttaa atcgctgaga gcttctttgt cgccatacaa ctttgaaaca tgtttaaatt
    52681 ctatcatggt atcctttttc cttttcttct ctttttctcc ctagactgat gaggcttcct
    52741 ctaaaatata cttttccaat gactgcttaa aacggcaaag cgattttgga agtaaaatgt
    52801 cattatcaag taagtaatta tccacatctt ggtttagttg gtaggcaaca agaagtgggt
    52861 tactgtgttt aattaatcta ttagaagctg ctaaaagtag ctgcgacaag gccacatttt
    52921 cacgattttc tggataatca taagcgtgtc taatcacatc gtataagcgc tgtcgtttct
    52981 tttccattta tactccttta tttttgtact tttacgctaa tacaataaca attaaattat
    53041 aatttttatg aattgttttg tcaatgactt cttatcaaaa gaagtgtatt aggcagtttg
    53101 aggaaaagaa agaactgggt attttatttt aaaaaaacag agtaaatcaa atgatttact
    53161 ctgtttggga tgtgtaacct agagtgattt gtataactca gttgcatttg ccacagtgaa
    53221 accatattct tcgaagatac gatttcctgg agctgaagca ccccaagtgt caatggtcaa
    53281 tgtttttcct gctaggccga catattttgc ccagccaaag cttgaacctg cttcgatagc
    53341 gagacgttta gtcacagctg ctggtaggat gctttcttta tactctgctg actgttcgtc
    53401 aaagatattt tgcgatggca tagatacgac gcgaacatga atgccttctg actcaagttt
    53461 atcttgagta tctaaagcta atttaacttc tgaacctgtt gcaatcaaga taccttcaag
    53521 gtcgcctttg gcttctgaca agatgtaagc tcctttgtta agaccatctt ctgccaattc
    53581 ttttgtgccc tcaagcactg ggaggttttg acgcgtcaat acaagcatgg ttgggcgatc
    53641 tgtttcagca atggcacgtt tccaagcagc atttgtttcg ttaccgtctg ctggacgaat
    53701 aacgttcaag ttaggcattg aacgaacact tgccaattgt tcaattggtt cgtgcgttgg
    53761 cccatcctca ccgacagcga tagaatcatg tgtcatgaca taaactgttg gtaagctttg
    53821 gagcgctgcc atacgaacag ctggaagaag atagtttgag aagacaaaga aggttccacc
    53881 gtaaacgcgt gttccatcgt gaagggcaat accgttcatg gctgcagcca tggcaaattc
    53941 acgaacgcca aaccagatgt tacggccttc ataatgacct ggttggaaat ctgtttcagc
    54001 cttaaccata gtgttgttag atgctgaaag gtctgctgac ccaccccaga aagaggctac
    54061 ttgttctgaa atttgttgga tggcttgttg actggataca cgactcgcca ttgagctacc
    54121 aagttcgtgc gcttcaagtt ctacttgagc agcttcgtta gcaaaggctt tttggtattc
    54181 tgctgctaat tctggatatt ctgcttcata agctgcaaac aagtcattcc aggcttgttc
    54241 tgctttttca ccacgcgctt gaagaccttg agcaaagcgc tctgttactt cagcaggcac
    54301 ttcaaaatct tgatgagtcc attggtaagc ttttttggca aaagcaatgc cttctgctcc
    54361 aagaggagcg ccgtgaacag ctgaagttcc ttgtttttcg gcaccaaaac caataatggt
    54421 tttgacttcg atgatggttg gtttctcagt ttcagcttta gctgcttcaa tagcagctgc
    54481 aatttcttct aaatcgtttc cgtctttcac aaggatatgt tgccaaccgt aagcttcgaa
    54541 acgtcctttc acatcttctg tgaaagccat agaggttgga ccatcaagag agatgtcgtt
    54601 tgaatcatat agcaagacca atttcccaag ttttaaatgt cctgccatac ttgctgcttc
    54661 ttggctgacc ccttccataa ggtcaccgtc accattcaaa gcaaatgtgt agtgatcaac
    54721 gatgtcaaag cctggtttgt taaatttagc tgctaggtga gcttctgcca tggccatacc
    54781 aacggcattt gcgatccctt gaccaagagg tcctgtggtt gcttcgacac cgtctgtgtg
    54841 gttcacttct gggtgacctg gtgttttaga accccattga cggaagttct ttaaatcttc
    54901 tacagataaa tcataaccag ctaagtgtaa caagctataa agcatggcac ttccatgacc
    54961 tgctgatagg ataaaacggt ctctgtttga ccaattacgg cttgttttgg gattgatatt
    55021 catgaagtga ttccaaagaa cataggccat aggtgctgcc cccattggaa gtcctgggtg
    55081 tccagaattt gccgcttgaa tggcatccat tgatagggtg cggacagtgt ttactgccaa
    55141 ctggtcaatt gcatcaaatg tcataagtaa aacctctctg tttattacaa ctaaaattaa
    55201 acgttttcta ttgtctattg tatcacaaaa atagacgctt ttttcagaaa atcctccaaa
    55261 gtccctaaat tctttttctt tattttgcca gaaaaaaact agtttggaca tcattggtga
    55321 attctttttg acgatgaata taagagagcc tgttgacaca gtggccacag actctttagc
    55381 cttatttttt aaaggaagcc caatcttcca taaaggtttt caaaccattt gtcgttaagg
    55441 gatgttgcgt catcttagca aacaaggggt ctggaatcgt cgcaatgtgt gcgcctaatt
    55501 tagcaacagc ttccacatgg gctgttgtac gaatacttgc tgcgatgatt tctgcttgga
    55561 aatcgtacaa gtcaatgatt tcacgaaggt cgctgattaa ttgataagca tctgtgccaa
    55621 tatcttccaa acgaccgata aatgggctaa tgtaagttgc gcctgctttc attgccatta
    55681 aaccttggct tactgtgaaa atcaaggtca cattagtttt aatcccttct tttgaaagaa
    55741 tgtttgttgc ttttaaccct tctgtagtca ttggaatttt aacgacgaca ttgtcatgcc
    55801 acttagcaat gcttctagct tcttctacca tagcatctgc tgttaaccct gtcacttcag
    55861 cactgattgg gccatcgacg atgtcacaga tttctttgat aactgtttca aaatcacgtc
    55921 cttcacgtga gataatggtt ggattggtgg tgacaccatc tacaacgcca agctcattaa
    55981 tcgctttaat agcggctaca ttagctgtat ctaggaaaaa tttcatttct tacctccaaa
    56041 aattttcgat tttgttaagc tctatttgat aagctttttc aaatcatcta cctttagact
    56101 atcctacttt attattataa aagtgtaaca gtccttagaa aagaccaagt atcacacagt
    56161 tttgtgtgca aaactagact tagctgctgg gctgagtgag agttcctctt ctcgtgtatt
    56221 tttttgctgg aaaaggtctt tgagaaaagc ttctaaagca gtgagttcat agggggagct
    56281 atactgtttt aaccggtaat agggtaaatc ttgtctcggt aaacagacag tctgataggt
    56341 aatcagacaa tcataaactt tctgatgatc atagggcatt aattgaaaat ccctacgatg
    56401 ccccaaatga cgtctaatgg ccaattccgc aatggctgct tccaccttat tttgccccaa
    56461 ggcaagccct actaaaagag gctcatggtg gcgctcaatg gaaaaaatca acaatgctaa
    56521 aatgtcgtca ctcaactgct gactgaaatc cgtttcctga cccatttgca gcactaaatg
    56581 gtttatgata acccttaaaa gcgctctttt atcttcgcct actaattgat aaaggtattg
    56641 gctattggtt ggttggctaa ggatagctcc tttaaaaaag taagctttgg aaaaaaatat
    56701 ccccaagcca taaatgattt cctcctttgt ctgatggata atcacatgag ccttctttaa
    56761 aagccataag gcttctgaaa tgtgatcagc aataggacct ccaaaaccca aactatactt
    56821 catgctggca ataggaagta gaggataagc atgcaaaaag acaaagaggc tcttagcttc
    56881 aaaagcatca aattcaaggg catagcgtct taagtaatgt aaaagcatgc tttctaagcg
    56941 cttaaagaaa atattagatg tcataaagtc actatctctt aaaaaatgat cattgtagcc
    57001 tttttgaaag gacattcgcg cttgcgaaat cgccaaccaa atcaataatt gttctaaggc
    57061 ttctgccgat aatgactggc caatcagccg ctcaattaag gtagccaaat gcgaagcgtc
    57121 taactgattg accaaggcgt ctatgccttg tctggtcaag gtatggcgga acaattcaaa
    57181 atagaaataa cgccactgaa gctcacttcc cagttgtctg ccttgcgaga gcgccagatc
    57241 aaattctgat aaaagctggt tgaggtgagc tagttgtctg tttagagtag cttcactaac
    57301 catcagttca acggataagt tggtgatgtt aaagtgttta tggcagtaca tgtaagtcaa
    57361 tatctgatag gcaaccgatt ctttgagaag cagagctacc aaatcctccc aatggaactg
    57421 gccattttct tttaagctca gactgtcttt ttctaaaagt aattgacagg ctaaaccttg
    57481 ttctcgacac aaataattta ggttgtcaat gtattttaat agggtcactt tagacaagtt
    57541 tgatagcctc attaggtctt ttagccttaa cgtttcttta gcatgataaa gggttaccaa
    57601 gagacgatat tgggcccttc gttccttatc cattaagtct tcaatcttca tggcggagcc
    57661 tcttttcaaa taatttgaga caagcttcat gaagatgata agccaaatca ctgtgacctt
    57721 gtaaaaagag aaaatcttga aatgctaagt caccgtctgt aactttcaga gccagagcct
    57781 gacctaattg attggcgatg acaagagcat tggttttgga taggagctga gcgcctatta
    57841 aaatcccatc cgtttttcta gctattaatt tcagccaaaa gaggttttta gaatccccat
    57901 tttggtacaa atagctacac gtatccatat aaagctctgc ttcttcttct gtcacaccaa
    57961 cactcgcgcg ataataacca aagtgagaac ttcctaatac cttgaccgtc tgtaatggag
    58021 gaataggata tccagctaaa tgcagagcca gagcctgacc tgtcttcatt gcttggttaa
    58081 tcaaaggtgt atagtaatcc attcccaata taccaaaatg caatgaaacc atgtctccaa
    58141 tggcatagat attagcctgg ctggtctgta agttttcatt gaccaaaatg gtcttatcca
    58201 gagcacaagc cacttgtcct tgcaaaaggt gtgtatttgg cctaaagtta atggctaaaa
    58261 tagccaaatc accttggaag gtgtcccctt gttcggtatg agcgacaact tttccctcta
    58321 tctcatggat agccgtaaca cgcttattat taataaaggt gacatggtga atggacattt
    58381 ctgccattac aggggctatc agttctgcgt cagtctgata gaaatctgga cgttcggctg
    58441 cttcaatcag tttgacccgt ttgccttgta aggacaaact gtaggcaagg tctaagccaa
    58501 tcaagccggc accaataacc aagacctctt ggctagcctc aatcagtttt aaactagctt
    58561 ggctttcttc ataatatttg gttaccaaaa ctttgttggt ctgtgacgtc tcaatataat
    58621 gagactgggg gctagcaccc atggcacaaa caagcgtttc ataaccttct tcaaaaactc
    58681 gtccttgact gtctttgaga agcaaggtgt ttgagggagc ttcgatagct aacacttctg
    58741 cttgaataaa ccggtggtta gattctattt gtgctgctag gcaggctctt ccccacatag
    58801 catcagacag gtcttgaatg tctcctctga ataattggtt gataccattt ggaatataat
    58861 tgggacagct ttccttatca atcagaatga tttgggaatc tggattgagg tccttatatt
    58921 tatcaacaaa ggctagacca gcaaaggatg ccccgataac gtgtatggtc tttgtcgtta
    58981 atgtcataat agtattatta tagcagttgt ttttaagata tgaaagcgtt ttacctaatc
    59041 ctataaagaa aatgcaaagg agctggccta tgatagccaa cccctttagt gatggttagg
    59101 acatgacttg gaaaagcaaa actgctaagg ccgctccaat aattggtcct acaacaggta
    59161 tccaagcata agaccaatca gaatctccct tgttgttgag tggtagaata gcatgaacta
    59221 gacgaggtcc taaatcacgc gctgggttaa tggcgtaacc tgtcgttcct cctaaggata
    59281 acccaatccc aataaccaag gtacctacac agagggttcc tagtcctgct ggcatatcat
    59341 ataagccaaa tgccaaaata ccaagcatca agacaaaggt cccaaagatt tcactcaata
    59401 ggtttgagct agtatctcga atagcaggac ctgtcgcaaa tgtccctaaa atatcagcct
    59461 gactctcagc agccagataa tgtggcctga actgaaggaa taccagagtt gaaccaacca
    59521 tagctcccaa tagttgggca aggctatagg caatggctgt tgaccaggca atggttccac
    59581 tcatggcaaa agcaaggcta acagctggat tgaggtgggc aggggcaact ttgccactga
    59641 taaagactgc cacagcaact gcaattcccc agccagtcgc aatcacgatc cagccagaag
    59701 catgggtttt cgttttgggc aagacaaccc ctgctaccac accatttcct agtaaaacca
    59761 ataaggctgt acccaaaaat tcgccaaaga tatccatatt aaccctcctg atggcctttt
    59821 aaggcactca aatcattgtc tgcaatcacg cgacgaagat cgtcttcttg tgccactctt
    59881 tcctgatcag accattcaaa atgtttagcc atttcattaa tcactggggc aatcaaagca
    59941 tctaggctat ctcgcataaa taagaggtga tttgttcttc tcaagaaata atctgtcggt
    60001 ttaagagcca tttcataatc catcgcataa tgtaaggaca aggtttcagc taaacttaac
    60061 ccttcagctg ctgttaattg acgagttaag gcaaagactt ttggcgcatt agaaccataa
    60121 aggtttgcca aatacctagc atcatccatc gaaagaccac taagagttcc taattgagca
    60181 taggcttcta tttccgaatc tacattggct ggattgattt cacctcctga aacaggatag
    60241 gtttttgaat tgataagctt gaaggatttg ccaaactctt ctttgagggt ttgaataatc
    60301 cctgtcaatg ctccttcagc cattttgcga tagtcggtaa tcttaccacc tgccaaggta
    60361 aagagtccat tctcatcacg gtcaaaactt gaacctcgtg acactgcaga cggatccaat
    60421 tctttttcag atgtgctggt ttcaacctgc ttaatagctt tttcaacagc ttctcggcta
    60481 tcttcgtggt taatataggc tttgacagta tcaaccaagt gatcaaaact atcatcactg
    60541 actttaccgc tgttgccacc attgtagtca gaagcactat tacctgataa caaggggcga
    60601 agaccagccc aactgctttc aatatcatca atggtcacgt tggcatttgg aaagcggtta
    60661 ttgacaacgc ctaacaaata atccacatct tcttgagtaa cttgtgggtg ctccaagtct
    60721 ccagtgtagt ccgtgtccgt tgttccaaaa taagtttttt cttcacgtgg caagacaaag
    60781 accatacgac catcatttaa ccctgtgtca acatagacag gttgagacac tggtaatttt
    60841 tgacggtcca ctaccagatg cacccctttt gtagggcgca tttgatgaat cggttgtccc
    60901 ttatgagaga attgacgaat ctcatcactc catggtcctg tggtgttgat gactaattta
    60961 gccttgataa tgatttcttg atctgacagc agatcacgcg ccttcacacc aataatctta
    61021 ccattgtcat ctagcaagaa atcttctgct ttcacatgac tagcaataag agccccatca
    61081 cgattagctc gtttgatatt ttcaataaca agccttgcgt cattattgcg gaaatcaagg
    61141 taaaccccac caccaagcaa gccttcttgt tttaagtctg gttctcgttt taagacttct
    61201 tctttggtta acaccttgtt ggccgctggc gtattggaca cgcctgctaa aagatcatac
    61261 aaatccatag cgaccttcaa acggaacatg ctaaaggtgc tgccaggttc gtcataaaca
    61321 ggtaataaca tagggtctgg ttttggaatg tggggtgcaa tttgttgcac cacagcccgc
    61381 tctgacaccg tatctgaaac tacctccaca tcaaattgtt tcaagtaacg aagccccccg
    61441 tgaaccaatt tggttgaacg gctagaggtt ccttgcgcaa aatcttgcat ctcaatcaga
    61501 cccgtatcta ggccactagc tgccgcctga agtgccacac cagcacccgt aatacctccc
    61561 ccaataatca gtaggtctaa atctctttct tgcatttttt ggagagctaa gcgtcttgtt
    61621 tctcttgaaa attccattcc atcctcctct agttattttg catcgtcatc tgcatcttct
    61681 tcttgggtga aaacttgagt tgctttaaca gcgcgcttcc aacccttgta taatttttct
    61741 ttgcgcgatt cattcatgct agccttaaag agctggcctg tggcatttaa ctctttcaaa
    61801 gcatccatat cttcccaata ccccacagca agccctgcta agaaagctgc tcctagagct
    61861 gttgtttcta aatttttagc acgggcaata tcaattccta aaatatcagc ctgaaattgc
    61921 atgagcatat tattcatggc tgcacctcca tccacacgga gctgttgaat gtcaatacct
    61981 gaatccacct gcatggtatc aataacatct cgcacttgat aggcgataga ttgtaaggtt
    62041 gctttgacaa agtcttcttt gctggtacca cgtgtcaagc caaagacaga tccacgcgca
    62101 ttagaatccc agtaaggagc tcctaaaccg gtaaaagcag gcacaacata aacttcatcg
    62161 tcactagttg atgctagagc gaactgttca gattctggtg aagtctcaat cattttaaga
    62221 ccatctcgca accattgaat ggcagagcct gcaataaaga tggaaccttc caaggcatag
    62281 tgaaccttcc cattaatccc gtaaccaatg gtggtcaaaa gattattact cgataactgc
    62341 atctcatcac cagtattcat gataatgaaa gaacctgtgc cataagtgtt tttcaccata
    62401 ccaggctcaa aagctagttg gccaaacaaa gctgcctgtt ggtcacccgc catacctgaa
    62461 ataggcactt cgcccccata aaaatgaaag gcagctgttt tgccataaat ttcagaattg
    62521 gatttaacct ctggaagcat atcttttgga atatttaaaa gctctaaaat ctcatcatcc
    62581 catgttaagt ctttaatatt atagagcatg gtacgagccg cattggaata atccgtcaca
    62641 tgaacagcac catctgtcaa tttccaaacc agccaagtat caatggttcc aaaaagtaac
    62701 tcgccttttt cagctcgttc ttgagcacca ggaacatggt ccaaaatcca acggatcttg
    62761 gttgcagaaa agtaagcatc aataacaagg cctgtctttt catggatcat ttttgtatgg
    62821 ccatcttgtt tgagttgctc agcaattggt gccgtctgcc gtgattgcca cacaatagca
    62881 ttataaatag gtacacccgt ttttttgtcc caaaccactg tggtctcacg ttggttggta
    62941 attccgattg cttcaatttg gcttggtttg atgctggact caataaaagc acccgcaata
    63001 acagactgaa ccgaattcca aatctgatta gcattgtgct ctacccaacc agcgtgtggg
    63061 aaaatctgag ggaattcttt ttggctactg ctaacctttt cccctttttg attgaaaata
    63121 atcgctcgtg aacttgttgt tccctgatca atagccatga tatacttctc ttgcgacatt
    63181 cattaccctc ctttaagtaa gcgttttcct atctgattct attatagcta attttatcag
    63241 aaatatatta tcaagaattt ttaaagctaa aaaaaagctg ataagatagg tagcttatcc
    63301 cactagatga tcttgaaaaa tccactgatg acaaccacgt ctcctcattt ctaacgaggt
    63361 aatctttctt atcaaagaaa atcaaaagac ccaacaatca ctctgctaat ccagagtcat
    63421 cattgggtca taaagagaac taagcctcaa aggcaacacg gtatcaaaca gccatgccta
    63481 agaggcaaag acaattggac acaagagtta aggctgtctt attcattaca gttcttgatt
    63541 agtcattgat tggttcagaa gatttttcca caatatcccc tgagttggcg tcaatggtat
    63601 aactgtattc ttgatctttg ttttgaaatt cgatttcata cacggctttg ccatcttcat
    63661 tatcttgtgt aactgatagc atttgagcat cagcttccgt aacagaagca tcttttaacg
    63721 caattgattt ggctttgtct tctgaaagtt taactttctt gctagtttga cttgtctttg
    63781 gttgattatc catatgatcg tctttatcat ccatatcaca ggctgcaaga ctgagtaaag
    63841 agaggctggc tatggctagt agagagaatt ttttaattgt cataagtact accttctttc
    63901 tttgatttct tctattataa ctcaaacaca tggtttttcc taatattttg actatacaat
    63961 ataaaaacgt gtggtcactt tgaagtatca taccatttaa aataaaagct aacagtcatc
    64021 acgataaaca aaaagcagtt cagagctgct ttttgtctta tgattttggg tcatctaatg
    64081 aacggccgtg caagcctttt tcacgttgca cctgtcttaa tttttcaggg gtcacgtcgt
    64141 ttccttcttc gtccaccaat ttgatgcctt cgatatggtg tctgacagag cgacgatagc
    64201 cttcaatgta ttcttcacgg agttttgcct gttccacttt ttcaggtcca gtcaagccta
    64261 ccgttttttt ctttttagcc agctcattga tacgagcaat ttttttagga tccatgttaa
    64321 gccactaaga gcctgggaaa aaagtataag gcttaaaaaa ctgacttgac tctcactgtg
    64381 aaaagcaatg tttaaagacc ttgttttttc cactcgggta ctgaactcac ttttctagct
    64441 aagtccccaa cggctctttc ctttctattt acttggtgtt tagttggtta aaagcagcaa
    64501 tggtcttagc tttgcttact aaatctgata aaatagctaa acggttgttc ttaagggctt
    64561 gatcttctgc cataaccatt gtgttatcaa agaaatcatt aatcactggg ctaagggcaa
    64621 agacctgttc taactgctgg gcagcactgc ctgctagagt caagccttga atagctgcaa
    64681 acaaagtgtt ttcttgctca ttttcaaaga ggctagggtc cacctgaaca gaagcgtccg
    64741 ctttttctgc caaattaaaa gcacgtgaca aagattcaac tgctggtttg taattttccg
    64801 tatggctggc tttgacaaga gcttcagctg cggccaacat ttctggaacc acaaaggttg
    64861 aacttgctag aatagcttcc cgaatgtctt ttggtgcggc tttgcccatc atcttatcca
    64921 cacgagcacg gataaagttc atcacatccg ccttattggt ataggtcaaa ctatcaaagg
    64981 acaagtcata taagctatct accagcttat ccattgggat gcgccatcca aaataatcaa
    65041 gaatacgaac gataccctgc gttgcccgac gaagcgcata agggtcgttt gaaccagatg
    65101 gaatcaagcc aacagaaaag aatgacaaga gagtatccaa tttatctgcc aaggccagga
    65161 cagcgccaac tttggtttca ggtagcgcac ctcctgcagc atcaggtaag tagtgttctc
    65221 ggatagccct tgccacagca gcatcttcac cagctagaag ggcatatttt tcacccataa
    65281 tcccttgcag ctcatcaaat tcaccaacca tacctgttaa caggtcaaat ttgtaaattt
    65341 gggcagcacg gtcaacagct gtgacttcct cagcagatag gttggcttcc ttagcaagtg
    65401 atgcggcaat gacacgcgta cgatccatgt gttcagcaag agagccgatt ttttcatgga
    65461 aggtcacatt ggtcaatttg gcaaccaaat cagcaatctg caatttctga tcctcacgcc
    65521 agaagaattc accatcttct aagcgagcta ccaaaacttt ttcgttccct ttaataacat
    65581 tttcaatggc ttgatcattc ccattacgaa ctgatacaaa gtttggcatc aagtgaccag
    65641 cctgatcacg tactacaaaa taacgttggt ggtttttcat tgatgttacc aatacttctt
    65701 ctgggacatc aaggtattta gcctcaaaac ttcccatgaa agctgttgga aactcgacca
    65761 agttcaaaac ttcattaagc aagtcttcgt caatgtcaac ttgcacaccc tgctccactt
    65821 caagcgtctt gatttgctcc acaatcatct cttgacgctc tttagcatca gcgataacaa
    65881 actggctgcg caaatcagcc tcataagaat cagcacttgt gatagtggtt tcagtaccta
    65941 aaaaacggtg accacggctg acgcgtccag aatgaatatc caagaagtca agttccaagg
    66001 cctcatcatt caacagaact gtcaaggtgt gaacaggacg aatatattca aaactattgt
    66061 tagcccagtg catgctgact gggaaggtca ttgctgacaa cacttcagta acgcctagaa
    66121 gcacttcctt agcaggtttt ccagcttcgt gtttggtcac ataaacgtat tcttctcctt
    66181 tgacttcgcg gaattcgata gcatctgtgg tcaagccttt gccacgaaca aatccttgag
    66241 cagcttttga gaaattccca tcagcatcaa gggcaatttt cttagcaggc cctttaaagt
    66301 cctcagtcaa atccgtttgc tgatcagcta atccagacac acgcactgcc aaacggcgtg
    66361 gagttgaaaa ggtttgtata tcttcaaaag agagacgatt ttctgttaag aaagtcgcca
    66421 agcgctctcc cagttgtttt tcacttggtg tgaccacata ggctggaagt tcttccagac
    66481 caagttcgat tagtagattt ttactcataa ttaagatacc aagggcgtta agcggacacc
    66541 atcaaaatag caaagcgacg caggtgcttg cacctaggaa gtcttggtct ttttgacata
    66601 gtccgtagcc catgttcagt tcctttctct aaaaagtatc tttttgattg ttcccttagg
    66661 taggggggac gcaaagtgaa attatccagt ggataatttc agaaaacaaa agtgttccat
    66721 tcctagttag ccagcctaaa gtctcgccaa ctccctcgtt cgataagtaa ccttaccgaa
    66781 ttgtcactac agcgggagta accttgactc ggcgaccttc ggtcgcccac ttcttgctcg
    66841 ctcttaagat tacaaagctc gcaactagat catctttaaa tcgacttatt cgtcatcttc
    66901 agctagcaag attgcgcgtg ttgcttcatc caacagtgga aatccaagct tcttgcgttc
    66961 tgcaacaaag gtcttagcaa cgacacgtgc caaattacgg atacgagcaa tgtagcctgc
    67021 gcgttctgtg acggaaacag cgccacgggc atccagcagg ttaaacgtat gagaacattt
    67081 gagcacgtaa tcataagctg ggtgaaccaa accttcttct agggcacgcg aggcttcttt
    67141 ttcaaacttt tcaaagtttt caagcagcat gtcttggtct gatatttcga aggaatattt
    67201 tgaatgctca tactcaggtt gtaagaagat ttcaccatat ttaacacctg gtgcccactc
    67261 aatatcatag accgaatcca cttcttgaat ataggaagct aagcgctcaa gaccataagt
    67321 tacttctgct gtcactggag atgtcgcaag gccaccaact tgttggaaat acgtaaattg
    67381 tgtgatttcc attccatcaa gccaaacttc ccaaccaagc cctgctgatc ctgttgatgg
    67441 gttttcccag ttatcttcaa caaaacgaat atcatgttct aaaggattga tgcccaattt
    67501 ttccaaagaa gcaaggtaaa gttcttgaat atttgatggt gatggtttca tgaccacttg
    67561 aaattggtgg tgttggtaaa gacgatttgg gttttctccg taacggccat ctgcaggacg
    67621 acgtgatggc tctacataag ccgcattcca tggctcagga cctatagcac gtaagaacgt
    67681 gtaaggactc atggtcccag ctcctttttc attgtcatag gcttgcatga gcatacaacc
    67741 ctgatcattc caatattgtt gtaaggtcaa gatgatttct tgaaaggtaa gttttttaga
    67801 catttcgtac tcctttgata gtagtaaaat ggtatatcat tgacaatcgt ttttttgtca
    67861 tcagtaaaat acctgacgat gttactagca tgtattacag gtctaggcac caaaaaaccg
    67921 cattttgatg ctcctaaatc ataagaccta ggggcgtcaa aacgcggttc caccctaatt
    67981 tattacttca tttatatagt atctttttgg gcaatattga caaatatact taatcacact
    68041 gcccaaacgg aagcgccaat ctgcagtcct accattcggc tctaactacc ccgaactcgc
    68101 tttagataag atacttgcat cctttttcct agagtctagt ttagcataaa gccattagtt
    68161 tgtccatcat gagcttaagg ttttgttcga gtaccgtttg gaataatcac ttccgctaat
    68221 agcttgtttt cttctcgaat acgtaaatat attactacaa tgtagcatgg gaaaagaagc
    68281 atagccgtaa ttttagcatg gcaaagtaag gctatgccca ccagctcagg ggcgatattt
    68341 aaaaagtagt taggatgttt aatcgttttg aacaaccagt gatccacata tttgtggtct
    68401 tttgctaaca tcaattttac agtccaaatg tcacctaaga tacgtgtcac ttcatataaa
    68461 acagctactg ataataacat caacaaaaga cctaaaaaac taatgccatc aaacttaatt
    68521 tgtttaagca gcgcttcaat caccgcaaac acataaatca taatgtgaag taacgtcaaa
    68581 aatttcgtgt tctgagcacc aaattcctgt cctccttggg ctaatatggc tttttcattt
    68641 gttatcgatt tcttcaaaaa tactaaacga atagtaaaca tagctaacat cactaaaaag
    68701 atggtcacaa tacggctcct tattttcaat aatagtttct ttcacaaaac actaataaag
    68761 attatagcta aatgataaac ctttgtcaaa ccgttttcaa aaaagattta gcgaattatg
    68821 gctaaatctt tgtagttcct taaaaacttg tagtatcagg gttaggaatc gctgacattc
    68881 ctgagagata gcgaattgtt tttttatctt cttgtgtcaa gctcacatca aaaatagcca
    68941 tattttcctt gatgcgctca tcatgcaccg attttggcaa gggaataaaa ccttctgcca
    69001 gcgaccaagc taaggcaact tgtgccactg ttttgtcata tttattagct aactgctgca
    69061 tagtctcatt atcaaaaatc tccccttgtc ctagaggact ccaagcttcc aataaaatct
    69121 catttgcctt acaataatca accacttcct tttgatagca acctggggct aatcgaatct
    69181 gattaattgc tggagttatt ttagctgtct cttgaagagc ttctagatga tgcaccataa
    69241 aattgctgac gccaatgctt ttaataagcc ctgcttcaac cgcctcttcc atatattgcc
    69301 atgcttgggc atttgcctct ttccaagtgt tacgcagagc ttttgggttt ggccaatgga
    69361 taagatagag atccacataa tccagaccaa gacggtcaag agaagcagct aaagcgtctt
    69421 ttgccccttc ataactatgg gcgtcattcc agagtttagt tgtaataaat aagtcttctc
    69481 gtagaacccc agaatccttg atggcacgac ccacactttc ttcattttta taaatagctg
    69541 cagtatcaat atgacgatag ccagccttga tggctgctaa ggtagattgg taagcttcct
    69601 caccatcggc tgcttggtaa gttccaaatc ctaaaacggg aatctcatag ccacttgtca
    69661 tttttactat tgttaccatc acaaaaacct ccttttatca atatctgtaa gcgattactt
    69721 taatctattc tatcataaag aaagaaaata caaaaagaat tggcctgcca gacatagcta
    69781 ctccaatcct tttgtatctc ttaggcatca aaagcttttt gcccatttaa ataggttgca
    69841 acaagtgtta aatccttatc aagaacaata aagtcagccg catgcccagc tttgatttga
    69901 ccacatacgt cgtcaatacc gacagaaaca gctggcacat aagttgccat atgaatggct
    69961 tctgccggag ttgcgattcc ccaggccact acatttctaa ggccgtcttt taatttcaaa
    70021 atagatcctg ccaagtttcc actctcttta agacgagcag tgccatttgc cacaaccaca
    70081 gagaattccc ccaagaggta atcaccatct ggtgaaccac ctgctcgcat acaatccgta
    70141 atcatggcta catgatcatg ccctttttgc tgcatcaaaa tatcacaagc aactggtgac
    70201 acatggtggc catcacaaat caactctgcg taagtatttg gaagattata aaccgctccc
    70261 accattcctg gttcacggtg ggtcaatcct cgcatgccat tataagcatg aacccaaaca
    70321 ctagcaccag cttgaacagc ttctttagcc tcttgataag taccatttga atgccctaag
    70381 gccactgtta cgccttgttt tgtcactgca gacacaaatt ctttgacacc ctcacgctca
    70441 ggagcaaggg caattttttt gatgagccct ttagcagctt tttgccaagc atcaaattcc
    70501 tccaagcgtg gggttttcat ataacttggg ttttgagcac ccttatattc ttcggtaaaa
    70561 taaggacctt caaagtagat accttgtatt ttagcacctt ttacctgatc agcaactgaa
    70621 gcaatagtcc ctgatacttt ttctaactgc tcaaaggtag aagttaaggt cgtcggtaaa
    70681 aaagacgtta ctcctgttgc taatagtcct tcactcattt gatgaatccc ttgggcagaa
    70741 ttatccatga catcagctcc cgcatagcca tggatatgcg tatccacaag acctggtgca
    70801 atttgataac cggtgtagtc aatgatttgc gcatctgccg aaacaatttc tgtccactcc
    70861 ccaaaaacac catcatgaag acttaggtag ccagccggtt tcacctctgt tgggtaataa
    70921 aaacaatctg ctttaagata gcatgtcatc ttttttcctc ccttttttcc ttattatacg
    70981 ccttattctt tactttgtaa atggtatata ccactttttg gattcaaaaa agaaaacgtg
    71041 gatgattatt aacgttttct ctttttttaa agctggtgtg aaagtacttt ctctgctaaa
    71101 ttcaaggcat gatctgtgat gcgggtatag tgggaaataa tatcaataaa attaatacct
    71161 gcttgtgccg tacattctcc acaattcaag cgcttaatgt gggttttacg taatcgtcgc
    71221 tctttttctt caatttcttt atggcgagtc acaatagttt gcgccaagtc tgtatcacta
    71281 tcaacgatag ctctaatggc atccagtgtt aaacaatgcg tcaattgata catctctgtc
    71341 aattcttgac gagcagatat tgaaaaacca atttgtttag atatgatgcc ttcaattaga
    71401 atgcctaaag actcagaatg atctccaatt ctttccaaat cacgtgaaga gtcaagaata
    71461 ccagccaaga cttcattttc acttgggctg agggcttcgt tagaaatatc aaccaaataa
    71521 gtggttaact cctcatcgat ggtatcaact gctctttcat aacgcttgac cttttcccca
    71581 aatttatcgt cagctgtcat aatataactg taagaagctt caaaagcttg aatcgcataa
    71641 gaagctaaat gaaccaattc cttgtgggca tttcctagtg cgatagaagg ggcttgggta
    71701 ataagtaagc gatctaaata aagggcttcg tatttgacca cttcatcttc tcctggaatg
    71761 agtctagtca caatcatagc tagtagacta atgaaaggaa ttaataagat ggtattagtg
    71821 atattaaaag aaccgtgaga aaaagcgata gtcatctcag gtgttaaact caactttgat
    71881 tgtagccata acatcaatga tgtgaatggg actaggataa tcataaaaat aattgtaccg
    71941 atcaaattaa ataacacatg agctgctgcc acacgtttag cagcaatatt tgaacctata
    72001 gctgctaaga cagctgtaat gcaggttcct atatttgagc ctaacaaaat aggaatagcc
    72061 ccctgtaagg tcaaaagacc gcctgaaaac agtccctgta aaatcccgat aatggctgcc
    72121 gatgactgaa tcaacatggt caaagccgtt ccgataaaga caccttggaa gggtttatca
    72181 cctaatgtcg ctaaataatt ttgaaaggct gacacagatt tcaaaggatc catggcatct
    72241 cccattaggt tcagtgagaa gaaaattcct ccgacaccaa aaatgatacg cccaaaattg
    72301 ttgagctttt tattagaggt aaagaaaaga caggctgcac caataaaaat catgggcaag
    72361 gcgtaatctc ctagtttaaa accaattaaa aacgaagtga tagtcgttcc aatattagcc
    72421 cccataacaa ttccaatggc ttgtcgcaaa tttagcaaac ccgcagaaac caaaccaacc
    72481 gtaatcacag tgacgcctga actggactga attaaggcag acatggcaat tccgactaag
    72541 ataccaaaaa agggattact ggtgtattta tcaatgtaat accttagttt atctcctgct
    72601 gcttgttgca gaccatctcc catatacttg atactgaaaa gaaagagacc taagcctcca
    72661 aagaaatgaa atgcaatgtc ttgccaattt actgacacaa tattgtcctc gctcaatttt
    72721 atagtctatt ctattttaat gtattacggt ctttatcaca aggttttttt aagcgtttct
    72781 gtgtatacca atgtcaatat ttgcatatta ttggtttgat aaggtgttag gcttttccga
    72841 tattttacat catttgtttt tgcacaaatc ttttcatttc gtttaattag aggtataata
    72901 tggctacgat gaaacaatat cataaaggag attccatgac taaatcacaa aaagaggcgc
    72961 tttattggat gttgagtgtt ctaactatca ctctaatagg tggctcctgc cttatttttg
    73021 gatcccaccc tcaaacgcaa gataaggtag ctaaacattc taaaagtgct gctagtttac
    73081 taaaaaaagc agttaaagca gttaatgacg ctgatcgttt agccactgca gctgctatcc
    73141 aagaagccca gaaagctgtt gataaattag cagaatcttc taagaaaaaa acgctacaag
    73201 aacagctaaa cgttgccaaa gcaaagcaag agcaagaaga tgcagctact caagcagtta
    73261 aagctgctga ggagactctc aatcaaaatc ttaaagatat cgcccaaaaa gcagttaacg
    73321 acttaagtaa caaaggtaaa aaagccgctt tacaatctcg gttagacgct attttaccag
    73381 caaaacccat tattgatgaa tttccaagac aaagtggaga aataacagat aactcttact
    73441 ggacaccttt cccaggagac gtctcagata cttatgataa ttcccagtca cctactttag
    73501 acccaagctc agaatcttca gcttcagatg ttacgccaca acctagtcat cctgatccaa
    73561 ttccacctca gacctcttca gaaccttccg actcaggaga caagcaatca tcaaaagagt
    73621 aatacaaaaa tttttcgtaa aatcaatcaa taaacgtttt agacggctat cttagtgatt
    73681 agtcttcctg atatcttaaa aaagctagct caaatcaaaa gagtctagct ttttgttttg
    73741 ttagataaca ttaaatttcg tagcccatta aaagtcctcc gtcttcagca taaaagctac
    73801 acaaacctga ggtccttcca gtttgaatca cagcatcagg atataaagat ttgatttttt
    73861 cactgatctg ctcacaaatt tttggatttt gagcatgagc aatgtaaact tttccgcctg
    73921 cataaccctc tttttgaatt tcttctatca aagcagaaac tgcttttttt tgaccacgcg
    73981 ctttttgaag aagttcaagc gttcctttat tgctagcttt cccaaccatt ctaatattga
    74041 gtaagccaat tactttacct actaatttac tcagtcgacc atttttaacc aaattatcaa
    74101 ccttggcaag cacaaaaatc aaacgtgttt tttgctgata agctgtgatc tgtttgacaa
    74161 cttcttcaaa ggataatcca agattgatca accgctcaag ctccagtacg agcaaatcca
    74221 tctcgccacc tgctgataaa gaatcgatta ggtgaatatt gacattagga ttttcttcaa
    74281 gaagttcatt tttagccagt cgtgcactat tatgactgcc agataaggtc cctgtaattg
    74341 tcatcacgat aacattatct gcacctctat aggcctgcaa aaaggcttct gggcttggac
    74401 agctagatgt cgttgcttta gacgactggt acatagttgt catcatatta tcgatatcta
    74461 atccatcatc atctctaaaa atttctgtgc caatctgtag ggtcaaaggc acacgttcaa
    74521 agcgcaactc tttggattgt ctagtcaaac ttctaagatc acatcctgaa tctgttacaa
    74581 ttttccaagt cattttttat ccttcttttt ctctaatttg tgttcggtaa caaagaccag
    74641 attattaagc cttcgctaag atgcctaggc taatggtaat aactagtcat taaatcctat
    74701 gttttattac tagccttttc aatagttagt aaagtcatct aatagagcta tacaaggagg
    74761 taatgaggct cctgataact aactttagtt gacaaactaa gacttttccc ataaaattat
    74821 atcattatta agtcggtttt tgctactgat aactcatcag atgtaacact tgaaaggtat
    74881 ttgtgatgac tgataaagca ctctcaaaaa gatcacttca aaacttaaca caatttaata
    74941 aagaaacacg acgcatagca cgtgaatcta tggaaatcgc cttagtaaat cttctagaaa
    75001 caaaaccttt aggtgatatt acgatttcag aattggtgac gaaagcagga gtatctcgta
    75061 acgcttttta tcgtaattat acctctaaag aagtcattat agaacaactg ttagtagggg
    75121 ttatccgtcg tatttttcgt ggactaaaac aatttgatat taaaactcag gcttatcaag
    75181 cctggctcta tctttttact gaagctaaaa aagaagctca gcttcttaaa atgattttca
    75241 aacatcacct gcaccatctt ctaacacgat tagtcactaa acgtctgaaa gcttatcaaa
    75301 aattaaaaga caaaaaacaa tcgcactata agcgcctttt ttggagcaat gctattgttt
    75361 ctgtcttgac aaactggatt tcagatgaca tgatcgttcc tgccgaagaa atggctgcta
    75421 tgggcttgcc tctattaacg taaaaaggtt ccttttggga acctttttac gttaatagtt
    75481 agtctttttg agctgcaagt gcaaactgac ggatagcctg ggccacaccc gccatatcat
    75541 tagtcaaagt gactttgtca gctaatggct tgatagctgc tgaagcattt tccatagcaa
    75601 ctcctaaacc agcataagtt aacatctcaa tgtcattggg agcatcccca atagccatca
    75661 cttggtcagc agttaaaccc aaatcttcta ctaattcttt gagagccgat gccttgctga
    75721 ctccctgagg gagaatttct aaaatattat cttggctacg aacaacatga aaactctgac
    75781 taagctgatt tctcaccgca cgttcaaagg catctagcgc agctttttct cctaagtaca
    75841 tggcttgaaa aatcaggcga ggagtgtccg acagctctgc taaggagaca ggcttgacaa
    75901 tggtaaatac caaatctcca tcttcctgca caaggtctgg cacttcttct tcaagcacca
    75961 aataatcgtt ttcctcagtt aaagtcaggt aaatatctgg aaagctttgg cttagctctt
    76021 ccagcaattc aatatctgaa accttcaaca tttttgaatg gcgtaattgc cagtcaggac
    76081 tactataagt actacagcca ttattgataa tgaggaattc ctcttgtgtc aaacctaatt
    76141 ggtcaaaata gggccttgtc cctgactgag gccggcctgt gcataagaca atttttaagc
    76201 ctgactgagc tgcttcttgg atggctgtga tattctcttt tggaatctgt ttgtcctggt
    76261 ttaataaggt gccgtccaaa tcaattgcaa ttagttgaac catcctatct ttcctctttc
    76321 catttgattt tagggaggtt ccatttttta cggttgccaa tcatgcgtaa agtcgtgagt
    76381 aaaacaacca aggcataaca ttcaatcgtt gaatctgcta gtttaaaatg caaaacaata
    76441 gctgcaagaa tagaccaccc agcatagatt tcactacgca aaacactagg ttttcgccct
    76501 gccagaatat ctctgacaac accaccgcct gcaccagtca acacagctgc tacaatgaca
    76561 gcacttaaag gctggttaag acggacagca tgcaaggctc cttggacact aaaagctgcc
    76621 agaccaatgg catcagtcaa aacagctgcc cgtacccaac ctctagctat tagcttagga
    76681 aaaagcataa tcaaaaccat agcaaagaaa gcgcaagtga attctggctt ttgcccccat
    76741 aaggcctcta taggtaaacc aattagggtg tttcgaatgg ctccgcctcc aaaggctgtc
    76801 acgaaaccta aaataaaaat ccctaaaata tcaaattctt cttccatggc aacaatagca
    76861 ccagaaagag caaaggcaat ggtcccgatg atatttaaaa tttcccacat atcaattgtc
    76921 ataagctacc ctattgtctt ttagtcttct tttagtttac cacgttttcc tttaaaaaat
    76981 aagtagaaaa agataaaatg taaggataaa aaagcaagga taaaacccat tttcatcctt
    77041 gctacaaaag attcaaacaa ttatccccat acttatctta tcacatcaat gagagctgct
    77101 tgataggata aggttgtttt agattttttc cgtccaaggg ctagcggtct cttcgagtac
    77161 cctgtttaac tcgtcaatat tttggaagcc ttcagtgcat agccactttc ttgcttcgtc
    77221 ctctccttta gtaatataaa ctggaacgga tcctgcccac gtggcacgcc cacacaaaac
    77281 accgctaaat tgagcacctg ctgctgctgc aaagtataat gtctcttgaa aaagtttggc
    77341 agatacgcct gcactcaaat agatataagg gaggtggctg gcagcttctt ggtcttgaaa
    77401 agctttaata gcctcagctt gactgtaatg gacttcccct tcagtaaaac cttctacata
    77461 agccatatta acaggaacct ctacttttag cacatcaacg ccaaaacgct tatccgaaaa
    77521 tactgacata gcaccgttaa ccttatgtgg cttaagcttt gcgtatgccg cactgttgtt
    77581 atctgatatt ctctcatcat aactcaaaag ttcaagaaaa aaagggatgt cttcagctgt
    77641 acattctgaa ccaatgcgtt caatataagc ttgtttttgt aaattgattt gttcatctcc
    77701 atcaacatca taatagagca aaaatttaat agcatctgca cctgctgctt tcaaccgttt
    77761 gaccgaccat tccactaagc aatcgggtaa acggctagtg gttgtagcat cataacctgt
    77821 tttttcgtaa gctaacagta agcctgtctg attagctctt accttagtag ccagcaaccc
    77881 atattctgga tctaataaaa tagatgaagc ataaggcgtc aattcctcag aaacgagaac
    77941 tttcaatgtt tctatctgtg taactgtcgc ttctccttct tgatgtgctg ccatcatttg
    78001 cttcagtgca cctcgttgat caaaagctaa agctgatatg attccttgat ggctcacttt
    78061 ttctaagtaa tgtcttttat ttgctgtgat tgtcatgtga tacctctctt acttgaagtt
    78121 gctgatataa ttgtttaaaa gttgccatag tcatcaaatc ttgataatag tgagtagcta
    78181 gtctcttagg cagactgcct gagaagttaa gacatcaaac ggcttagcaa tagtactcat
    78241 gtggctcaaa gagacttcga cttcggcttc gtccacatca ctgtagggac cagcttccaa
    78301 aatttttgtc tgcatgcctt catgtaaaac agcaatacaa tttctcgttt cccctttgat
    78361 tttgaaaaat tggttagaaa tgccctgttc ttgtaactga tgaatgataa agtcacccag
    78421 cttaccacca ctaaatcctg ttgccataac tgaccagctt ttgctaacat tctggtcaca
    78481 tttagctcct tatcgccagc tgtttttgcc gttctgtcaa cacgattaac cgtgtccata
    78541 gccagacaat ctaaaggata ggaaatagcg acagaaggat ttaaggtaac tgttaaactc
    78601 atctcttctt cctaatcgtg atactcacca cgatcccatt tttccaaaaa ttctgtaaaa
    78661 aaatcaggat cttcttggtt ggcatgatga gtttccaagt gggctatttt agcaattagc
    78721 ttcttattct cttcagtttc tttgtattct gccttgataa aagcgtctat aatatcacac
    78781 ataagaagtt caccagtgat tttaccacca aagccaatca cattggcatt caattcttcc
    78841 ttggcataaa gcgctgttgt catatctcta acaagggcgg agcgaatacc tggtaccttg
    78901 ttcacggcat tattaatgcc aactccagtt ccacaaatac aaacacccaa gtcagcttgg
    78961 ccattaacca cagcttcgcc gacttttttt ccaaaaatag ggtaatgggt tcttgtatgg
    79021 tcataagtgc cacagtcaat aacgtcatag cctttagatt tcaaaaaatc agaaacagcc
    79081 attttttcgt tggtgacaat atggtcacaa ccaatcgcaa ttttcatcac tttatcctcc
    79141 tttaggccat tttattgagc atgtcaacac gaatttgatg acgaccacca tcgtagggac
    79201 cagtcacaaa acctttgacg atattcttcg ctaattctgg acctacaatc tctgccccta
    79261 ttgtgatcat gcgggcatta ttgtgaccgc gcgtcatgta agcagagcgt tcatctgaca
    79321 cttcagcagc aaccattcct tttaattttg tggctaccat aaagggacct gctccgtaag
    79381 catccaccat aatgcctaaa cgaccttctg cttcattaac ggctttagcc accgctaatg
    79441 tgttatcaat aaaatcactg ttaatatcag tcacgtcaat aatgtcatag ccttcttctt
    79501 gaagaaaact tttgatcaat tcttttaatg catttccgtg tgcatctgca cctaaaataa
    79561 tagccatagc ttttcctttt ctaacccaaa acgcttgcca atctagagaa gggggacatg
    79621 attacctgtc cttagatcaa gatgattgcc agtagtctta gtgtcttcca ttatttcttt
    79681 caagacaaag cacttgtggg ttcccacaga gcgccttgcc ttacatgaga aatactcttt
    79741 tcacgttagg gggtaaggca gaaatacctt acgcagttat ctgctattct ccctaatttt
    79801 ttagtcagtc acctgacctg attttatttc attgttttcg catactcagc gttacgtgcc
    79861 ttcatttggt tagcatacca agcaaagaga cctaggtaaa tggccacaaa gatgattaac
    79921 gtaatgattg aggcaatctg acctgttgtc gcttgaccaa tcacataacc aaagattttt
    79981 tccattggtc cttcaagtgt tgaatgcgta atcaaggaac cagcgcttgt acctgctgga
    80041 aaagccccta cttttttagc caactctgtc gcaaatggag caatcatagt tcctgacaag
    80101 aggaataatg gcaataagag ggaaccaaaa ataatcatgc gaatcaaacg accacgtgtg
    80161 accacaagaa gagctggtgt catccccata gcaataattc ccgccaatgg taaaatccca
    80221 ttgccaactt ttgataggag aacggcttca atcaacatga ttggggcaag aatattggca
    80281 caggcccaga tttcagcgcg accagcaatg aaaggccagt ccaaaccgat attgaaacga
    80341 cgcccatgca ttctagcatt ggcaaaattg gtaatccctt gtgacaaagg ctcaacagct
    80401 gcgataaacc aagaaccaat caaagagaaa agttccaaac aggcacccgc ggtaaagcct
    80461 agaccaaacc aatttttgat agattcaaca gtgaaatgag gatctcccat aatcccaatc
    80521 acaaaaccta gagccattcc gataaagaac ttagagcccc agaagccaat ttttttgttc
    80581 aatttagcag catcaaagtc atatttatct agcccaggaa agaccttgtc aaaaatctta
    80641 tctaagacca taatgattgg attcatcatg tagttcatat gggtcgatgt catcggtgat
    80701 tgaggccctg ttccaaggag atcatcaaag gtgggtttca tcaaatcaga gttaatgatt
    80761 ttcagtaccc caacaagaat aactgccaca gtagcaatca aaagagacac aaagactggt
    80821 aaatggttgc gagccgcata ccacataatt aacaagcccg taatggataa gtgccaaata
    80881 tcaaaaatat cgacgtcaag ggtgtctgtt tttttcatga caatcatgac aatattaacc
    80941 accagcatca ccagcaagaa ataaagggta taaggggaac cccaggtaat tgttgcaagc
    81001 ggtgcccagc ccacatcaat aatattcaaa ctgattcctg tatttttgac aaaggcctgt
    81061 aaagactctg aaaaagctcc tgttaaaatt ccaataatag ctccaatccc tgtcaaagcg
    81121 atggccaact taatcccgcc ttccagtgcc tttgtgaatt taaccccgaa aatcatggct
    81181 aaacctgtca tgacaatcag catgaccaca cctgatccca actgaatagg aaatcccaga
    81241 atcttgttaa taatgtctaa aaaaggttgc atcatcttgt ctccttatgt ttttattaac
    81301 tcactgcaag tggttttctt taatcacgcg ctctaattca gcaaaaacag gctcactcat
    81361 gattgggata cgatagagaa tcggtcctgc ttctactatg ggaatcggca ggtcaaatcc
    81421 caagtcagtt tttgcaatcg gcgtaaaaat atcataacga gacaccaatt cttctgtgat
    81481 gtctttgacc atcaccgcat cacaatgcac atcatagcca cgatcagtca tttggctttc
    81541 gatagcatct ttaatttgat ggcttgagtt aacacctgca ccgcaggctg ctagaatttt
    81601 aatcatgctg aaacactcct ttttctatta aatagtttga aatagcttgt ttatcatctt
    81661 ttagactggc tagatagcta agattgcctt tcgtaataaa gaaggtaatg agattggata
    81721 gaatcgtcgt ttgaccctcg ttttgactat tgataataaa gaagaaatcc gttaccaaac
    81781 agtcttcctc tggattaatc atgtgcttaa aggtaagggc ttgactattt ctaacataga
    81841 ccacttgatc aaccaagcaa tacttggttt ctgtatgcgg aatagccgca tacaaaatat
    81901 ctgacccatc tttgaggtcc actttgagtc ctgtcggaaa taccgcctca cgctccacta
    81961 aagcctgatg gtactcttgc gtcacatacc caaccttttc caagtggcta gcaacaagat
    82021 caaaaagctc tggctgcgtc cttgcttcag taaatagaat attaggaaac actccctacc
    82081 gcctttctat aagtatcaat ttttaacaac tgtcatctca tcatcaacaa attggtaacc
    82141 gtttacaaaa tcattatagt ataaccttca acataattca acatttttac gcaatatttt
    82201 ttgttctata tgtttgtttt tgttttgttt attttgtttt attgaaatat gaaggtctat
    82261 atgctatgat aaacataagt aaataaacta tagaaaggag ccccttagat gttaaaaaga
    82321 gaaagacttc taaaaattac cgaaatagtc aatgagcaag gtattgttac tgtgaatgat
    82381 attattcaga ctttaaacgt ttctgatatg acagttcgta gagacttaga tgaactggaa
    82441 aaagccggca aattgatccg catccatgga ggtgcacaaa gcattaccat gcctaataaa
    82501 aaagagcggt caaatattga aaaacaaacc gttcaaacaa aggaaaaatg ggaactagct
    82561 tcatatgcga cacaactagt caatgatggt gaaacaatct ttattggtcc aggaacaact
    82621 ttagaatgtt tcgctgagca attaaaaaat cgtcagattc gcattgtgac caatagcctc
    82681 cctgtcttta acatccttca ggacagcgaa accattgacc tgattcttat cggtggtgaa
    82741 taccgatcta ttacaggagc ttttgtaggg tcccttgcca gtcaaaatat ctcatcctta
    82801 aaatttgcca aggcttttat tagctgtaat ggtatttata aaaacgatat tgcaacttat
    82861 agcgaaactg aaggagagat tcaaaagcta gcttttaata attctattga aaaatacctc
    82921 ttggtagata accaaaaatt caatgcctac gacttcttca ttttttacca tttaaacaac
    82981 attgatgctg ttgttacaga ttcgcaaata actgaggacg tcatcgaacg ttataatcag
    83041 ttcacgcaat tattagtagc ccacgaaaac aaggagtaac cgtttcatca agaatggaca
    83101 gcctgtcagc gcatcgtcct taaacacctt ctggcaaaaa tgatttgccc ccagagaggt
    83161 gtttttgttt tgctcggaac acacctgcta acgtcagagt ctttatgagt gaccacaaaa
    83221 aaagaagccc agattaaaaa actggaacct cttttgagat gaagtaaggc taccaaaata
    83281 acctaagacc atttatgtaa ttcaaatttg gtatccctca aagcacgctt gagtaggaaa
    83341 gttaaaggac gtcctgtcac cttagcctct cctttttcca aatttacctg gaccgattgc
    83401 acaccgggga cagctgataa tttttcagta accgttcttg cacaaccgtc acacgtcatt
    83461 cctgtaacct gataatgttt ttccatttcg ttttctcctt caaatggttt ttccttttaa
    83521 tcgcagggca ttcaaaacaa ctgatactga actaaaactc atggcaaaac ctgctaacat
    83581 cgggttcaat agtggacctc caaaaagatg aagtaagccc atggccactg gaatcatgag
    83641 gacattgtaa atgaatgccc aaaataaatt ttccttgaca attctcatag tcgctcgact
    83701 caatgacata gctttcacca aatccagcat atcaggtttc atcagaatca catccgccga
    83761 ttcaatggca atatctgtcc ctgaccccat agctatccca atgtctgcta cagccaatgc
    83821 cggagcatca ttaataccat cacctaccat tgcaactttt ctcccttgag agcggaggtc
    83881 tgctatcacg cctgcttttt gatcaggtaa gacttgactg atcacatctg taatccccac
    83941 ttgagaggca atagccttag cggtagcatc gtggtcacct gttagcatga tggtgtgaat
    84001 tcccagttga tgcaaagctt cgacggtagc ttgactatct tctttgacag cgtcagcaat
    84061 actgaaaaga gctcttagct gcccctcttt agcataatat acaagggttt gacctttccc
    84121 agaagcctta gcacaaactg actgaacaca agataaatcg ataccaagag ttgccattaa
    84181 agtagcattt ccaatcgcca aacgacgacc ttcaagctga ccagtgactc ctaggccggt
    84241 taaagactca aactcttcca ctggtagact atcgtaacca gcttcctgag cagcacgaac
    84301 aatagcctcc cctaaggggt gttgagaata ggcctccaag gaagcagctt cttgcaagat
    84361 aaggtgatca tctcccgaaa aaattaggag cttttgaaga cttggtttcc cctccgtaat
    84421 cgtccccgtt ttatcaaaaa caaccgtatc tacctgatga gcttgttcta agatgtcacc
    84481 acctttaaaa agaataccat tttcagctgc acgccctgtt ccaaccataa tcgctgtcgg
    84541 ggttgctaaa ccaagcgcac aagggcaagc aatgactaga acagcgatgg ctgttgtcaa
    84601 actaaaacga agactttcct gcatgaatac caaccaaaac acccctgtta acagagctaa
    84661 taccaaaacc accggaacaa agacacctga gactctatca gcaatagttg caataggtgc
    84721 tttattttct tgagcattct caactagttg gataatttgt gctaacaagg tatcattccc
    84781 aagcttatct ggtttaatcg tgagggcgcc tttcccattc aagctgcccg caaagacatt
    84841 atctttttct cccttttcaa caggaaaact ttcccctgtt aaaaaggatt catccaaact
    84901 gctatgtcct tccacgataa taccgtcaat agaaactttt tcacctggtt gaaccaggac
    84961 aaggtcatca tagctaacct cttctaacgg caacaattgc cattggctgt ttctccatac
    85021 cctcacaaca gtagccttca aggataagag cttttgaata gcttgggaag tacggccttt
    85081 agaacgactt tcaaaatact ttcctagacc aatgagtgtc aaaatcacta ccaccgattc
    85141 aaaataaagg gagtgcacaa agtgcgcctg gcccatactg atttcaacca ctccataaag
    85201 actataagca aaagcaaagc tggttgctaa agctaccaag gagtccatat taggatatcc
    85261 cttaaacaaa gctttaaacc cattatggta ataatgacga tttaatacta agactggaat
    85321 cgtcaagagt agctgactaa agctgtaaac gaaaggatag cgatctggtt gcagaaatga
    85381 aggaagccat aagcccacca tgtgacccat agctaggtat aatataggaa tggtgaatag
    85441 ggcagaccac aagacctgag accaaataac ctttaggtct tcgtcacgac gacctgtttg
    85501 catgtgtttt gcatgttcat caaagacttg tgcaccataa ccagcagctt ttaccgcttg
    85561 aataactttg gccgtttcta aatcatcatc ttgataagta accgtgagtt tctcggtcgc
    85621 taaattcaca acagcctgtt ctacttcagg caattgattg accgtttttt caattgttag
    85681 agcacaagag gcacaactca ttccctccac taaaaatatc tctttagcca ttaatacgtc
    85741 tcctttttct gacagtggca ctgcccaggc aggcaattac acggcacctc aagaactgca
    85801 ttttcttttt tgacttctag tagctcttgg aatgcctcaa tttcctctaa ggtcatcggt
    85861 aagtcataaa gccgttcaag aagtagacgc gtgtgttgcc gctgacaaat accgtctaaa
    85921 acagtcgcta gtgcttcttt ttgtagcaaa gtctcatcca aaagagcttg ataaatataa
    85981 gctcttcctt gccgataaga cgttaaaaga ttttttttaa ctagcctacc aatgagggtc
    86041 ttaatagtgg aatctgacca ttgatatttt ttccttaaaa tagtaataat atcgctactt
    86101 ttaatatcac cactggccca caccacacgc atgacttccc attcggcagc tgatatctgt
    86161 tgcataacgt caccttcatt cacaatatat ttacgtttgt aaattaatta taacgaattt
    86221 aactacattt gtaaataaat aacttttctc atttttctat ccttatattg acaaatgaat
    86281 cgtttttact ataatattat tgcaataaaa ataacattta cattaaggag atacccttga
    86341 aacatcctat tcgaaaaaca cttgttacct taggtctatt actgacctta tgcctgccga
    86401 ctccagttgc agctagttct cgttcttgga agagctggtt tatcgagcaa tatttctggt
    86461 taaaacgtga caagagttac tattctaaac aagatgatcc aagcttccaa agataccttg
    86521 atgcctgtcg tgaacaatct gataaacctt atcaactaga tactaattta gtcaatggta
    86581 cccttgtcca agaaaactta tttgacatgc aagtgtactc ttggaatgat aatggaaaac
    86641 ctgatcaaaa aacaattatt tatcttgccg gtggttctta tcttaacaat ccaacgacat
    86701 accatattaa tatgttaaag acattatcca caagtcttga cgctaaaatt gttttaccca
    86761 tttatcctaa agccccacgt tatacctata actatactat gccaaaattg gtcaatcttt
    86821 accaacacta ttaccataaa aatcagaatg ttttccttat gggagattca gcaggtggag
    86881 gtttagcctt aggtctagct catgccctac acaatgaatc agtccctcaa ccaaagcagc
    86941 tcgttctttt atcaccttgg ttagatgtta ctatgtcaca cccagagact ccagaatacg
    87001 aagatgctga tcctattcta tcttcttggg gattaaaacg agtgggagaa ttgtgggctt
    87061 actctgctga taataccaac catatttatg tcagtcctaa aaatggtccg atcacttatc
    87121 taccaccaat tactttattt actgggacac gagagatctt ttatcctgat attcgcgatt
    87181 atgccgcaaa actgaaagcc gctaaccaca atattacctt tattacccaa gaaggcatga
    87241 accacgttta cccaatttat cctatcgaag aggcaaaaac agctcaatac caaatcattg
    87301 atgccatcaa caaaactcct taatgagggg aataactcct acctgccacc agttaatctg
    87361 gtggtttttt tgtagtttgc accacaaaat aacaattaaa aagagcccta tcataatgat
    87421 aaggctcttt ctgtcataac atccgcaccg caatacttag gatttgttgt caagatctcg
    87481 taagagttga tcaattttat taccataggc gatggaattg tctttttcaa acaccaaatc
    87541 tggaattttg tacatggtca attgtttgcc aagttcacgt ttaatcgttc cagtcgcttt
    87601 ttcaagccct gtttgtgctt tttgattatc agatgccaag tcactcataa tagtgtaata
    87661 aactttagca agtgacaagt caccctgcat ttgcacttct gtaatcgtta ctccctgaac
    87721 gcgtggatca cgcacttttt tctgaagaat atcatttact tcgcgcttga tttccatccc
    87781 aacgcggtca atacgatgat tagccatagc catttccttt ccacattttt aaaacaaaag
    87841 ctaggctgaa agcccagctt atgacattgc tacctgtttt gataacgaca attaaaggga
    87901 atctgagaat tccatgacga gactggaagg aatgccccaa gtagctcatc tggtagaaaa
    87961 agtcattatt tccgacagag gaaaaacgtt acatctcaga ccttcttaac ccctattttc
    88021 tcacaatttc ttccataata taggcttcaa tagtatcgtc aactttaaga tcgttaaagt
    88081 tttcaatcat caacccacct tcttgagcat taccgacttc tttaacgtca tctttgtaat
    88141 gtttcaagct ggccagttta ccatcaaaaa taacgacact atcacggata acacgaacac
    88201 tcgaatcacg tgtcacctta ccgttgatta ccataaagcc accaattgtt cccactttag
    88261 aaactttgaa ggtttcacga ataatggctt caccaagaat tttttcttgg taaacagggt
    88321 caagtttccc tttcatggct tcttctactt cttcaatgac tttatagata atgctatgaa
    88381 gacgaatttc cacatcatcc gtatctgctt gttgacgagc ttgtggggta gggcgaacgt
    88441 tgaaaccgat aataacagca tttgatgctt cagcaagggt cacatcagac tcattgatag
    88501 cacctacagc agagtgaacg acattcacac gaacaccttc cacttcaatc tttacaagag
    88561 atgctgcaag ggcttcaaca gaaccttgaa cgtctgcttt gatgatgaca ttaacagtct
    88621 tgatttctcc tgctttaagg gtatcaaaga gattatcaag gctaacacgc tgtgtatttt
    88681 gacgttgttt gaggagggca cgttttgatc gctcctcacc agctgcacgc gcagcttttt
    88741 catcagcgta aacagcaaag tgatcaccag ccattggtgt ttcgttcaaa ccagtaatgg
    88801 aaactggtgt tgatggctcc gcagatttaa cacgacgccc aaggtcattt accatggcac
    88861 ggacacgacc aaaggtatta ccaacaacga ttgggtcttg aacatgaaga gttccttgtt
    88921 ggacaagaag tgtagcaata gcacctttac ctttatctaa gcgtgcttca atcacagtac
    88981 caatagcacg aaccgttgga tcagctttca attcttctac ttcagcaacc aaaaggactg
    89041 tttctaatag ttcatcaata tttttattaa atttagcaga tatctctaca aattcgcact
    89101 ctccgcccca agcagttgag atgataccat attctgccaa ttctgcgata acacgttctg
    89161 gattagcacc tggtttatca attttgttga tagcaacaat aattggaaca ccagcagctt
    89221 ttgagtgatt gatcgcttca atcgtttgtg gcataacacc atcatcagct gcaacaatca
    89281 aaatggtgat atcggtaacg gaagctccac gtgcgcgcat gcttgtaaag gccgcgtgtc
    89341 cgggagtatc caagaaggta attttcttgc cagcttcttc aatctggtaa gcaccaatat
    89401 gctgagtaat tcctccagct tctcctgttg ccacacgtga gttacgcaaa gtatcaagca
    89461 aagttgtctt accgtggtct acgtgtccca tgatagttac aacaggtgcg cgttctacaa
    89521 tattttcagg attgaggtaa ttttcatcct caaagaagcg ctcgatatca gcatcatcta
    89581 cttctacctt agccttagcc tcaataccat aatctaccat caataattcg atagtatccc
    89641 catctaaaga ctggttttga gttgccataa cacccatcat aaacagcttt ttaacaattt
    89701 cagcgggttc gcgtttgata cgttttgcga tttcggcaac tgtcatgcct tcagtatatt
    89761 caaattcttt tggcaattca tggaatttac gctcggttac tggttttgga gcggtgttgg
    89821 tattcttaac atttttgcct tttttggtct ttttattttt attccagtta ctattttttt
    89881 gatttctcac ttggttttga ctattccaac tcttcttatt tttcttttgt ccttcttgtg
    89941 aatgatgagt taactcacga ttcttttcag gacgtgcttg ttttttacgg cgattatcag
    90001 cagtagattt agcattaata tttgatgact ttaatttagt ttctgcttct tcaatagatt
    90061 tcaatgctgc ttcacgatgg ctcatctcct cagcttgtgc ttttagagcc gcttctttag
    90121 cttcttgtct tgccaactca gctaaacgct tagcttcttg ctgtgcacga aaacgtgttt
    90181 cactttggcg tgagtattca gcaatttgtt cagcttttaa ggcagcagca cgagctttga
    90241 aatcaatttt aggacttttc gattgaggct cttgtcgtcc ttgctttttt tggtttgtga
    90301 atcgaccatt cttgtgattc tccttagcaa aggaacggtt acgatcacca actagctgat
    90361 gattatcatg tctaggtgat acattcgatg cttttcgctc aatacgctta tcgtttgtat
    90421 caccttgaga acgatgggta atcctcttat ctccttgttc gttagtttga tgattattgg
    90481 gctggcgata acctcctcga cgttcttgag aacgatgaga agagccattt gcttgttttc
    90541 gagcagcctg ttcctttgca cgagcctctc tttcagcttt aaaattacga ctctttggct
    90601 tagagacctg tgttttctct acatgctcag aacctgtttc tttgaccact gttacagagg
    90661 gttgagcaac ttctttgggt ttgactgttt gagaagctgt cacatcaggt ttagaagcct
    90721 ttgaaaaact tgaaataatc tttttcgcat ccgcttcttc aacacttgat gcatggcttt
    90781 tcacatctaa tcctaagtat ttagcgtgtt caaccacctc tttactactt ttaccaattt
    90841 ccttggcaat ttcatgtaat cttttctttg acaatttgtg tcctcctatt catctattcc
    90901 ataagagtcc tcattttctt tgaaaatcca gcatctgcaa tggcagcaac cttccttggt
    90961 ttacctagtg cagcacttaa ttccagtgca ttcaacactg tggagacttc tacattataa
    91021 taattacttt tatctgtcac tttttttgtc acattaggac cagcatcatt ggctaaaaat
    91081 actaatatta cctgctggtg ttgaatagct tttactacta gttcttcacc tgaaatcact
    91141 tttccagccc gttgagctag accaataaga ctagataatc tttctaaatt agtcaagacc
    91201 taactctctt cttttgattt tgtgatcaac ataagcaatc aagtcatcgt aaaaactttc
    91261 tggaatgtcc attgagaaac tcctgttgaa aacttgtttt ttcttggcca ttaaggcctc
    91321 ttgattgtct aatttgatat aagcaccacg accattttgt ttaccagttg gatcaatgaa
    91381 aacttgacca tccttagttt ttacaatcct aagaagatct cgtttagcaa taatttcacc
    91441 agaaacaagt gattttcgta aaggtatttt tttgacttta gacatcaaac acctcttttc
    91501 ttatacttcc tcggcagtca taacatcgtc aacaactggc tcttccacag ctgttgctgc
    91561 ttctttttcc gcctcaagac gatcatattc gctagctgat ttgatatcaa tacggtagcc
    91621 agtcaaatgt gccgctaaac gaacattttg gccgcgacgc ccgatagcta atgataattt
    91681 gctatcagga actactaccg tagcacgttt aagatcttca tcgtcaaaaa gtaccatgtc
    91741 tacttcagcc ggagcaatgg cattgtagat gaactcagct ggatcatcta cccattgaat
    91801 cacgtcaata ttttcttcaa ctggaatttc aagccccgtc ttagcatcta cacgttttgg
    91861 atggaacttg ctgatgacct ttttaatatt acttccacca cgtccaacaa ttgttccgat
    91921 ggcatcaacg ttaggattat gactgcgcac agcaaccttg gtgcggtcac ctgcttcacg
    91981 agaaacactc atgatttcaa cagtaccatc aaagacttca ggaatttctt gctccataat
    92041 acgtttgatg aattctggat ggctacgact aacaaagacg ttaactcctt taggattatt
    92101 ttcaactttg tagacataaa cgtcaatacg gtcatgtgat ttgaaagttt cacctggaat
    92161 ctggtcttgg tgagacaatt gtgcttctaa ggaaccaaga ttgacataaa taaaacgttg
    92221 atcaaaccgt tcaactgttc ctgtcataat ttcaccttca tgctctttgt attcattgaa
    92281 catcacttca cgcatttggc ggcgcatctt ttccataata gtctgtttag ctgattgagc
    92341 tgcgacacgt ccaaattcat tgacagattc ttcaaagcga atcttatcac ccaattcata
    92401 ggcagaactg atagcaagag catctttcaa actaatctca agccggctgt caaaaacttc
    92461 ttcaacaacc tcacgaaccg tgaatacttg aaaatcagct gttttttcat taaattcaat
    92521 aacacatgat tctgattgac catagcgacg tttataggca gactttaatg attctgtcac
    92581 tgcgtcaata atatctgctt tatcaatgtg tttttcttct tccaaaatac ggaaggcttc
    92641 tagcatttct ttgctcataa tgttatctac cttgcttgta aagcttggca aaaatccttt
    92701 cttaaattaa tacgatcaat agccccctaa aggctccctt aattcctttt gtttagcttg
    92761 tataaactct ataggtgttg tttcaaattt gcttaagcgt tcctaaaaaa gtttagtgct
    92821 ttgaaataaa agttataatt tgacagccat tctcacctta gcaactgctt gatatggtat
    92881 attcacgatc ttatgacgtg ttttatcaag ataatcaatg gtcaacgttt caccatcaaa
    92941 ggctagtaag tctccttgaa aaactttcac cttatcaata gcttgataaa gactcacatt
    93001 gatataagag ccaactgctg cttttaaact gtcagctgtc ttaagcggac gctccaaacc
    93061 tggactagag acttctagca tatattggtt tggaaaagga tctggatcaa tcgtatctaa
    93121 cagcggacta ataatattcg tcaagtcaga tgtatcttcc actgtgattc caccttcctt
    93181 atcgactaaa atactaagga tgtagtcact acccattttg tcatattcaa cgtctactaa
    93241 ttcataaggt gccttaatct caggtgttac tgtcttggtt acgatatcga taatagatgt
    93301 atttgctatt ttgattacct cctctatttt tatgctcttc tctaagataa ttggtccttg
    93361 ggaatccact taatacaaaa gcggcgagac atatcccacc acctttctgt attatttaag
    93421 cccattatac cataatttaa gaggaatgca aggatatgca ctttgtttta ctcacaagga
    93481 gaggagggga ttcgaacccc cgagccccgt taaggactac acgctttcca agcgtgcgca
    93541 ctaagccact atgcgacctc tccattacta aagaagttaa tactgtatca actcctttat
    93601 gttatcatat tttgaaacaa aatactacta gaaatttgcc tcaactcggt aaatgacttg
    93661 acctttatta gagaacttct cttcatattc tgtcatgaca tttccttcat agttactagc
    93721 gtgtaagtca agccagatct gtctcaaggt catgccgtat tgagaaaaac tagctaaact
    93781 gtactcaaac aagccccgat tatcggtttt aaaatgaatt tcaccgtgtt ctggcaagat
    93841 acgcttgtaa gtgtctaaga aatccttgta ggtcaaacga cgtttttcat gcttggtttt
    93901 tggccaagga tctgaaaagt tgagatacat catatccacc tcaccatctt caaaatagtt
    93961 ggttaaactt gatccatcca ctcgcagaag tttgacattg ggtacttctg aagctaatac
    94021 cttatccaag gcgtagctta ggacagataa ttgaatatca atgccaatgt agttaatatc
    94081 aggatttttc aaggccatcc ctgtgataaa tccgcccttt cctgaaccaa cttcgatatg
    94141 aataggacgg tcatttccaa aaacgtcatg ccaacggccc ttggcatctt ctggatttaa
    94201 tatcacatag tgtgggttat tagctaagtg ctcctcagca ccttttcgtt ttctaactcg
    94261 cattatttct ttctaaatat ttctctaaat tttctgaggg cataaatctc ctgattcaca
    94321 tgctccatgt cacgcttgtc aaaacacttg agaatttgtg tcaggtgaga aaattgacca
    94381 taccaaataa ttttttgcat aaccttgtca ttatttttat agccataata agacagccat
    94441 tctgaccaac gagaccgtgg aatatagtgg ctcaacaggt aagcaacatc atacatccga
    94501 tcagtcagac gaacagaatc ccaatctact aaaaaaatca taccactagt agtaatcacc
    94561 caattgctat gtttaatatc tccatgcaca atcgttgcta cttctgattt gaactctggt
    94621 aagctccgtt ttaattcttt aacgatagct tgtaaatatg aattttgctg aatttgcaag
    94681 ggtgcatttt gctcaaaatc aaccaataaa tcgtatgggt tttcaatctt ataattgagc
    94741 tgaagcagtt gattgactaa ttttttagat ttgtgaaggc gcaatagaat atgaatgatt
    94801 tgcttactgt tcatatcttc tttggtcaat gtacggccgt taagccattc ttgggcactc
    94861 atcatatcac cattgcccat gcgtttggcc caaagtaact gtggcgcaat ctgttctttt
    94921 gctaaggcag gtagaatagg ggtcgtattt aattttataa agacacattc cccatttgga
    94981 taagtgcctt tataagcttt gccacttttc ccacgtaagg gagtcaaggt aagttcttgt
    95041 tccgtcgttg tcaccttatc gccctccttt tctatctttt atagtcgttt acccctattt
    95101 tacttgtttt aggctactta gtcaatgatc ttctttaact tataaggtag atatatacaa
    95161 gctatgaaaa ccatacctac aatcaaaatg agtgcttttg gcgctgatga gcaacacagc
    95221 atattgacga ttaacattaa aaagcttaaa cctcgtaaaa aacttaacat atttttcttc
    95281 ttgctccgac tattttcagg ataaagacta gtcatataat ggtaatcgta gtgataataa
    95341 agtgaaagta attggaatac aactaaatag ttaaaaatga gtgctaaact tactgacaaa
    95401 taaagattat ggataaaaaa tacagataat gagcttaata gcattagtcg taaaaataag
    95461 cccaaataat ctgaactacg taaaaaggct ctagcataaa gagacagcca aaggtttgaa
    95521 ggagtttgct taactaattt taaaagagga tttagataag ttctttcttt cacttttgta
    95581 gaaattcctt tgactgttgt aaaaagagaa taaaacttta aaatactttg cttgcgattg
    95641 ctttcaaatg cgacagcttt tgcccaatct aaacgatttc ctctcaaaaa atatcttgtc
    95701 tttcgactaa gcactactct ttttagtgcc aataatatca aaactaagat aataaaaata
    95761 aataaagaca gacctaaacg tctaaaaata ggatataaaa agagcaatat agcagtctgc
    95821 aaagttcccc aaagcaaaaa agagagtcgc tcagcttgtt tgatataaga aatcacttct
    95881 tcttcttttg gaagtaagaa atgctgatct gcctcttcta gatacgttgc tatagatccc
    95941 atactgagca ataatgggat caatatccca agacaaacct gaataggtag atgattcgtt
    96001 ggaaaatggt ttagtagctg accatactgc accatagcaa agcctaataa aaacatcaac
    96061 accaaaacaa agtgatcatt taagacgtaa cgaaggtatt tgttttgttg tttttgaaag
    96121 tcttgacggc gtttcagaaa taatgctttc atacttaatc ctcttttgtt aatgcaagat
    96181 agatatcatt taagctcgct gaacgatcac caaaagcttc ttgcaagtca gcaagagttc
    96241 cttgggcacg aacttgtcca tgatgcaaaa ccacaaaacg atcacacatt ctttcagcag
    96301 agtccaaaac atgtgtactc atcaaaatag attttccttt tgctttttcg acttctagcg
    96361 tttggattaa gtctgaaata gctaaagggt ctaaccctaa gaatggttca tcaagaataa
    96421 atagacttgg atcaatgaca aaggcacaaa taatcatgac tttttgtttc atccctttag
    96481 aaaaattgac aggaaaccat tcaagtttgt cagttaaacg aaacatttcc aagaaaggtt
    96541 gtgctcgttt ttgtgccact tctaagtcga tatcataagc catagctacg gtgttgatat
    96601 gctctgataa ggtcaattct tcatagagac taggagtttc tgggataaaa cctatttttt
    96661 gacggtaggc aactgcattt tctgctagag ttaaaccatc aatagaaata cttccttgat
    96721 aaggcttcaa aaagccaata atttcgttga tagttgttga ctttccagca ccatttagcc
    96781 cgatcaaacc gactaactct ccattgtcta cagaaaatga gacatcgttt aaaacaggga
    96841 tattgtgata tcctcctgtt agatttttaa tgtttaacat ataatttctt tctagttttt
    96901 gatatactta taatatatta taacaaattc aagtagagaa ggtgatataa aatggaaaat
    96961 tgtatttttt gcagcatcat tcaaggggat atcccctctt cgaaagtcta cgaagatgag
    97021 caggtcctcg cctttttaga tatctcacaa actacaaaag ggcatactct agtcattcct
    97081 aagcaacatg ttcgtaactt actagagatg actgctgaga cagctagtca tctctttgct
    97141 cgtattccta aaattgctcg tgctatccag ttagctactg gcgctactgc catgaatatc
    97201 attaacaata acgaagcctt agcgggacaa actgttttcc atgctcatgt tcatctcgtt
    97261 cctcgttata atgaaaaaga cggtatctca attcaataca ccactcatga gcctaacttt
    97321 cctgtcttgg aaaagctcgc ccgacaaatc aatcaggagg ttagttcatg aaagttaaaa
    97381 ccgtgatagc cgtcggatta ttatctttta ccgcttacaa agcatatcaa aaacgttgta
    97441 ccataaaaga gctgttatcc atcagtagac aagcaaaaga tgctgcccaa cttgatttag
    97501 ataacattaa agcaaacctt gacctcattc acagtcaagg aaaagtaatt caaaatatta
    97561 gtcaggactt ggcccataaa tggcgctact ttaaccaaga gacacaagca cacctcactg
    97621 aaatccaaaa tcgtatggcc aaatatcaag aaaatagtga gctaatttct agtgaatcac
    97681 ctacttgcca aaccgtcatt ttaactaaca actattccag atagtattat ctccctcata
    97741 cactttattt gaaatcacag acagctatca tctttgatac ctgtcttttt tatattcaaa
    97801 atcggatatt ttaaacataa aaaccctcag aacgttaggt ctgagggttg atattagcag
    97861 gaggaactaa tgatccagac cctgatgagc tagactcatc agctgctaaa gcatctgatg
    97921 aagaagacgg cgtagttggc gtatggcttg aagcagtaga gtcctggtct gtactagcac
    97981 tctgataaga tgagccggta tctactccac ttgaataatt agcgtaagag ctatgactat
    98041 cagaataaga tggagcctgg cctgaagagt catagttgtt gtttactgtc tgagacttag
    98101 ttgacccata caacttttca taaacagtag catttgtttt taattgacta accttatgaa
    98161 gtcctaattc tgttcggata cgattttgga tttctaacaa atgattagag gtaacaattt
    98221 ggtatgatcc accatctgat aaagtggcat cttctccttt tagttgataa gtcttaatag
    98281 ttctaagtgc gtcacgataa cctaatagac tagggatagt gcgagaagag atttcgatat
    98341 tcgtttgcat attactactt acagcagata aaatcttccg ataagagcta atgctatcaa
    98401 gagcaaggat ttttttcaat accttttgaa tgacttcacg ttgacgcttt tgtcgaccat
    98461 aatctccctc aggatcatca taacgcatac gagcataaac caaagcttgt tcaccgttaa
    98521 ttttgtgtgt tccaggcgca acagtagctt gatattcagg ttcgttttca gcaatcgaga
    98581 taggaaaatc aaactcattt gtaactgtaa tccctccaac tgcattcaca agatcaataa
    98641 ggccttgcat attaatttga acatagttat caatggtgat attcaaaaga tcttgcacgg
    98701 tcataatagc catctgagcg ccacctgctg cataagcagc gttaagctta gcttcaacac
    98761 cattcatttc attatttttg ggtccagata acgtggttaa ggtatctcgt tctaaactag
    98821 tcatagttgt tttcttggtc tttggattaa ccgtaaccaa aatcatcgaa tcactgtttc
    98881 cttcccactt ggaggcacgc tctgaagagc ctgtatcaac acccatcaac aagatagaaa
    98941 aagctcttgt ttgtttaatg gcatcacttt tctttgaaga tgtcgaaaaa tctttaaagg
    99001 tctttgataa ttctcctgtt gagaaggtat aagcactagt tagatagaca cctaatgcca
    99061 agacagttgt taacacaata gctgtgaaca ttaaaactat tttttttcca attttcatcg
    99121 attcacttac tgacttacag atttacgcat atgataaaca tctaagtcat ctccattttt
    99181 tgatttgatg tcgttttttc gcatactttc aatacgaaaa ccatactttt tatacaggta
    99241 aatagcctta gtatttctta cttgaacgtc caacttaagg ctttcgatat aagggttttc
    99301 ttcagcccaa tcaagagcaa tctctaacaa taattgaccg ataccataac cacggtaagt
    99361 cttagtaact aacataaata catctgcttc aacttggcct tgggataata cttccccaga
    99421 aagatttaaa agccctacta ctttttcatc taatctagct agcaggcaaa aatcaataaa
    99481 agaggtttga cttcttgata aaaagtctga caattcttga ggaatagcct ctaatatagt
    99541 ctctacgcct gttataaaat ctgtttcttt ggcagctgcc gtcactaagg aaagtacagc
    99601 ttttgcatct tgaggtactc cttcttcaat aacgagactt tgctgaatca tgtgacatta
    99661 tctccagaag ctgacgagag cgctcaccat gcgctaacaa gtctagttga cgacctttgt
    99721 ctcgtttagt aatggtaatt tgcaaatggt cttgtaataa tccctctcct aataattctc
    99781 cccactcaat aacggtaaca ccattaccaa aaagaaaatc atctaaatca atagagtctg
    99841 gatcatcacc aacacggtaa atatctaagt gataaagagg tagacgtcct tcatattctc
    99901 taacaatagt ataagttggg cttttgatca tttgactaat ccccatccct ttagcaatac
    99961 cttttgccaa tgttgtttta ccggcaccta agtcgccaga caatacaatc acatctccaa
   100021 tagacaaata agtacctagg gtttcgccgt aagctttaag agtatattca ttttcactat
   100081 aaaacatagc aacattatat cagaaaaaaa acatacttcc aagcactacc tagaagatga
   100141 ctcaaataag gtattcgtaa agtaaaaacg cttctttata ttaaaggtta aaatcaacta
   100201 aagaagcggc agttagtagc aaaataagta aattatttgg ttataagata gttaatatga
   100261 tgaaatttac aatgaacaag aaggttgctc cccaaataat agggtgaata tcttttgttt
   100321 ttccctcaac aacttttact agacaataga aaataaaggc agcggcaata ccataggaaa
   100381 tagagtaaca cagcgccata aagaaagctg caaaaaaagc tggaagagca tctgcaaatt
   100441 tactccaatt aacatcaaga aaagaagaca ccatcatgac acccacaaca attaaagctg
   100501 gagccgtagc agcagctggg acaataccta caagcggtaa tagcaatatt gataataaga
   100561 agcatactgc ggtggagact gctgttagtc cagtacgtcc accttcagca attcctgctg
   100621 ctgattcaac ataggtagtc gtatttgaag ttccaaccaa agccccaata gaagtaccga
   100681 tagcatctgc aaaaagcgca cgatccattt ttgaactaaa gcctatacta ttttccaaag
   100741 cattctcatc gtcttgagag aaaatacctg ttcgacgacc agttccgata aaggtaccaa
   100801 ttgtgtcaaa agtatctgat agactaaaag caaaaatagt catgaaaact agcggtaaac
   100861 gacttgaatc gctaaaaaga gaactcaaac catcgaaagc tgcaaggaaa gttgtaccta
   100921 attcagtcca agcttcacca atatggctga tcccaaaatt gaggttggac acatccacta
   100981 ttcctaaagg aatacctaca agagttgttg cgacaatacc aattaaaata gcacctctaa
   101041 aatttcgaat cacaagagct gtcgttaaaa gtaaaccaaa aatagcaagt aatacaccgg
   101101 aatccgtaaa actagaaatc gtaggtacaa ctccaccatt ggcgtctaca aataatagac
   101161 catctgcaaa tgttttagcc gatgctttag ccggttcaac accatttacc attactatat
   101221 tttcagcaga gacagaaaaa gtaatgatat ttgcgttttt aaatcctaaa taagctacaa
   101281 agacaccaat tcccccacca atagcatgct gtaaactaac tggaatcgcc ttgatgatac
   101341 ttttacgaaa cttggttacg gtaataaaaa tattgaataa tccacaaatg aaaaccattg
   101401 ccaaggcttc ttgccatgaa aaccctaaag caaaaacaac tgtataagtg aaaaaagcgt
   101461 taagtcccat tcctggtgcc aacgcataag gcacattggc aaatagtccc ataattaagg
   101521 ttgatatggc tgctgcgata atcgtagcca aaaagacagc attagagggc atccccgctg
   101581 cacctaaaat acttgggtta acaaacaaaa tataggacat ggcaaaaaag gtcgttaaac
   101641 cagccataat ctcagttgag acagttgtcc cattttcgct taacttaaaa aacttttcca
   101701 ttgaaatgga gtctccttaa ttaaatagta ggtaaaatca aaaagcgctt atcactagat
   101761 aagtcttttt gacacctcat tattattgtt attgttcgta ttgaaatgaa caataacact
   101821 attttaccat ttttttgttc acctttcaac gtctatacct tcatttattc attaaaaaaa
   101881 cagttatcct atctttttta ctaatgaata cgcttaactt atcttttctc tttatcttgg
   101941 agcaaaattt gctataattt aattatgact aaaaaattga ttgccattga tttggatgga
   102001 accttattac atcatgacaa caccatctct acctatactc aaaaaaccat caaagctgtc
   102061 caagacaagg gccaccacgt cattatttca acaggccgtc cttaccgcat ggcattggac
   102121 tactatctgc agctcaattt aaagacccca atcattactt ttaatggggc cttgacccac
   102181 atgcctgaac aaaaatgggc ctatgaacat aatgtcactt tggacaaagg ctacctacta
   102241 aggttactaa aatatcagga tgatttccag atggatttta ttgccagtga gtatcgaaaa
   102301 aatgtctaca tcaccatgac caatccagaa agtatcgacc cgcaactctt tggtgttgat
   102361 gaaattactc aggacatggc attagagatt accaaaatca ctcgaaatcc aaacgcctta
   102421 ttgatgcaaa cgcatcacga agacaagtat gccttagcta aaaacatgcg tgctttcttc
   102481 aaagatgaaa ttgaaattga ttcttgggga ggccctctca acattcttga aatttcgtct
   102541 aagaatatca ataaagctta cgctctgaac tatctccttg gaatttacaa tatggataaa
   102601 aaggatttaa tcgcctttgg tgatgaacac aatgacactg agatgctagc ttttgctgga
   102661 actggttatg ccatgaaaaa tgctagccct gtgctactgc cttatgctga tcagcagctt
   102721 aatttttcca acgaagaaga cggtgttgcc aaaaaattgg aagaactttt cttatagtag
   102781 caaacgaaac cactattttt cagaaaatgg tggtttttct tctgtcaaca gctatcaaaa
   102841 aatgaaaatc attttaataa tttcaacatt tttcagcata t
//
LOCUS       DAUNLR010000003        72861 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUNLR010000003 DAUNLR010000000
VERSION     DAUNLR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72861
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.003"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            125..1339
                     /gene="sstT"
                     /locus_tag="VLL59_000190"
     CDS             125..1339
                     /gene="sstT"
                     /locus_tag="VLL59_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HER6508350.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(1394..2068)
                     /locus_tag="VLL59_000191"
     CDS             complement(1394..2068)
                     /locus_tag="VLL59_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HER6508351.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(2078..3469)
                     /locus_tag="VLL59_000192"
     CDS             complement(2078..3469)
                     /locus_tag="VLL59_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HER6508352.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSLEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(3538..4251)
                     /gene="rsmG"
                     /locus_tag="VLL59_000193"
     CDS             complement(3538..4251)
                     /gene="rsmG"
                     /locus_tag="VLL59_000193"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HER6508353.1"
                     /translation="MTPQDFYRTLEKDGFLLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEKNEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            4401..4958
                     /locus_tag="VLL59_000194"
     CDS             4401..4958
                     /locus_tag="VLL59_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HER6508354.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            5005..5901
                     /gene="htpX"
                     /locus_tag="VLL59_000195"
     CDS             5005..5901
                     /gene="htpX"
                     /locus_tag="VLL59_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HER6508355.1"
                     /translation="MLYQQISQNKQRTVVLLIIFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            6135..6668
                     /locus_tag="VLL59_000196"
     CDS             6135..6668
                     /locus_tag="VLL59_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HER6508356.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            6935..7621
                     /gene="covR"
                     /locus_tag="VLL59_000197"
                     /gene_synonym="csrR"
     CDS             6935..7621
                     /gene="covR"
                     /locus_tag="VLL59_000197"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HER6508357.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            7627..9129
                     /gene="covS"
                     /locus_tag="VLL59_000198"
                     /gene_synonym="csrS"
     CDS             7627..9129
                     /gene="covS"
                     /locus_tag="VLL59_000198"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HER6508358.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            9344..9838
                     /gene="nrdR"
                     /locus_tag="VLL59_000199"
     CDS             9344..9838
                     /gene="nrdR"
                     /locus_tag="VLL59_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HER6508359.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            9822..10997
                     /locus_tag="VLL59_000200"
     CDS             9822..10997
                     /locus_tag="VLL59_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HER6508360.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQENLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSCRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            10998..11900
                     /gene="dnaI"
                     /locus_tag="VLL59_000201"
     CDS             10998..11900
                     /gene="dnaI"
                     /locus_tag="VLL59_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HER6508361.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            11963..13273
                     /gene="der"
                     /locus_tag="VLL59_000202"
     CDS             11963..13273
                     /gene="der"
                     /locus_tag="VLL59_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HER6508362.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            13480..16578
                     /locus_tag="VLL59_000203"
     CDS             13480..16578
                     /locus_tag="VLL59_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6508363.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKQYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKSFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASNTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMKDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            16821..17423
                     /locus_tag="VLL59_000204"
     CDS             16821..17423
                     /locus_tag="VLL59_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508364.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            17463..18791
                     /locus_tag="VLL59_000205"
     CDS             17463..18791
                     /locus_tag="VLL59_000205"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HER6508365.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            18837..19319
                     /locus_tag="VLL59_000206"
     CDS             18837..19319
                     /locus_tag="VLL59_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HER6508366.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            19431..21005
                     /gene="mltG"
                     /locus_tag="VLL59_000207"
     CDS             19431..21005
                     /gene="mltG"
                     /locus_tag="VLL59_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HER6508367.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAAKRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            21078..21560
                     /gene="greA"
                     /locus_tag="VLL59_000208"
     CDS             21078..21560
                     /gene="greA"
                     /locus_tag="VLL59_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HER6508368.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(22180..23103)
                     /gene="yidC"
                     /locus_tag="VLL59_000209"
     CDS             complement(22180..23103)
                     /gene="yidC"
                     /locus_tag="VLL59_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HER6508369.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(23185..23463)
                     /locus_tag="VLL59_000210"
     CDS             complement(23185..23463)
                     /locus_tag="VLL59_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HER6508370.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNINDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
     gene            23724..24461
                     /locus_tag="VLL59_000211"
     CDS             23724..24461
                     /locus_tag="VLL59_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HER6508371.1"
                     /translation="MVITSKTNQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            24500..25000
                     /locus_tag="VLL59_000212"
     CDS             24500..25000
                     /locus_tag="VLL59_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HER6508372.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            25015..25704
                     /locus_tag="VLL59_000213"
     CDS             25015..25704
                     /locus_tag="VLL59_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HER6508373.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            25882..26124
                     /locus_tag="VLL59_000214"
     CDS             25882..26124
                     /locus_tag="VLL59_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HER6508374.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            26302..27096
                     /gene="racE"
                     /locus_tag="VLL59_000215"
     CDS             26302..27096
                     /gene="racE"
                     /locus_tag="VLL59_000215"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HER6508375.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            27093..28079
                     /locus_tag="VLL59_000216"
     CDS             27093..28079
                     /locus_tag="VLL59_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HER6508376.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKIKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDTVLIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLNELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            28058..28579
                     /locus_tag="VLL59_000217"
     CDS             28058..28579
                     /locus_tag="VLL59_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HER6508377.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTRLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            28576..29037
                     /locus_tag="VLL59_000218"
     CDS             28576..29037
                     /locus_tag="VLL59_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HER6508378.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            29034..29780
                     /gene="xerD"
                     /locus_tag="VLL59_000219"
     CDS             29034..29780
                     /gene="xerD"
                     /locus_tag="VLL59_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HER6508379.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKAMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPVTLEKYYKS"
     gene            29780..30481
                     /locus_tag="VLL59_000220"
     CDS             29780..30481
                     /locus_tag="VLL59_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HER6508380.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEDLEQDLLEKIEEYSRFKAVSQ
                     ALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAILKNNHTVI
                     ERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFVE
                     QLSNFGAIILRKEKK"
     gene            30478..31029
                     /locus_tag="VLL59_000221"
     CDS             30478..31029
                     /locus_tag="VLL59_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HER6508381.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLCAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            31149..31871
                     /locus_tag="VLL59_000222"
     CDS             31149..31871
                     /locus_tag="VLL59_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HER6508382.1"
                     /translation="MRINKYIAHAGIASRRKVEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            31868..32131
                     /gene="yidD"
                     /locus_tag="VLL59_000223"
     CDS             31868..32131
                     /gene="yidD"
                     /locus_tag="VLL59_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HER6508383.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            32309..32857
                     /locus_tag="VLL59_000224"
     CDS             32309..32857
                     /locus_tag="VLL59_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HER6508384.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      32966..33090
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            33169..33732
                     /locus_tag="VLL59_000225"
     CDS             33169..33732
                     /locus_tag="VLL59_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HER6508385.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            33734..34387
                     /locus_tag="VLL59_000226"
     CDS             33734..34387
                     /locus_tag="VLL59_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HER6508386.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILVIGLSRIYLGVHYPSDILAGFVLGFGILQFIYPFYKQKRFEWRFLLKQD"
     gene            34680..35600
                     /locus_tag="VLL59_000227"
     CDS             34680..35600
                     /locus_tag="VLL59_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HER6508387.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            35639..36193
                     /locus_tag="VLL59_000228"
     CDS             35639..36193
                     /locus_tag="VLL59_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HER6508388.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLLNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            36326..37660
                     /locus_tag="VLL59_000229"
     CDS             36326..37660
                     /locus_tag="VLL59_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HER6508389.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            37738..38529
                     /gene="pflA"
                     /locus_tag="VLL59_000230"
     CDS             37738..38529
                     /gene="pflA"
                     /locus_tag="VLL59_000230"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HER6508390.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            38660..39595
                     /locus_tag="VLL59_000231"
     CDS             38660..39595
                     /locus_tag="VLL59_000231"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HER6508391.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDISEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            39671..40324
                     /locus_tag="VLL59_000232"
     CDS             39671..40324
                     /locus_tag="VLL59_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HER6508392.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(40369..41406)
                     /locus_tag="VLL59_000233"
     CDS             complement(40369..41406)
                     /locus_tag="VLL59_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HER6508393.1"
                     /translation="MLFMVNKKRRPLLKSHRHLLGLYTSLILLLVSLMGLALSLGESH
                     LSFLDLIHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKLTIPISILIGMILLLVADTVGRVYLVGTNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(41367..42419)
                     /locus_tag="VLL59_000234"
     CDS             complement(41367..42419)
                     /locus_tag="VLL59_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HER6508394.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAESGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(42409..43341)
                     /locus_tag="VLL59_000235"
     CDS             complement(42409..43341)
                     /locus_tag="VLL59_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HER6508395.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEDKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEIIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDETGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(43367..44149)
                     /locus_tag="VLL59_000236"
     CDS             complement(43367..44149)
                     /locus_tag="VLL59_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508396.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(44395..45840)
                     /locus_tag="VLL59_000237"
     CDS             complement(44395..45840)
                     /locus_tag="VLL59_000237"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HER6508397.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECMTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            45928..47562
                     /locus_tag="VLL59_000238"
     CDS             45928..47562
                     /locus_tag="VLL59_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HER6508398.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAISQIAEQLIRVIWMLLTTFLIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            47731..48360
                     /gene="upp"
                     /locus_tag="VLL59_000239"
     CDS             47731..48360
                     /gene="upp"
                     /locus_tag="VLL59_000239"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HER6508399.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            48584..49174
                     /locus_tag="VLL59_000240"
     CDS             48584..49174
                     /locus_tag="VLL59_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HER6508400.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            49669..49944
                     /locus_tag="VLL59_000241"
     CDS             49669..49944
                     /locus_tag="VLL59_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HER6508401.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            50193..50828
                     /locus_tag="VLL59_000242"
     CDS             50193..50828
                     /locus_tag="VLL59_000242"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HER6508402.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGG
                     VAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            50846..51721
                     /locus_tag="VLL59_000243"
     CDS             50846..51721
                     /locus_tag="VLL59_000243"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HER6508403.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHTNAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQTERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQWEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            51740..51980
                     /locus_tag="VLL59_000244"
                     /pseudo
     CDS             51740..51980
                     /locus_tag="VLL59_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
     gene            52384..52707
                     /gene="yabA"
                     /locus_tag="VLL59_000245"
     CDS             52384..52707
                     /gene="yabA"
                     /locus_tag="VLL59_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HER6508404.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            52712..53575
                     /gene="rsmI"
                     /locus_tag="VLL59_000246"
     CDS             52712..53575
                     /gene="rsmI"
                     /locus_tag="VLL59_000246"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HER6508405.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVFVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQVDSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            53602..53994
                     /locus_tag="VLL59_000247"
     CDS             53602..53994
                     /locus_tag="VLL59_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508406.1"
                     /translation="MTEDQATILILGVYGIILAIFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(54041..54670)
                     /locus_tag="VLL59_000248"
     CDS             complement(54041..54670)
                     /locus_tag="VLL59_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HER6508407.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTSENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQSLSKLTGTAIVHGTKII"
     gene            54970..55326
                     /locus_tag="VLL59_000249"
     CDS             54970..55326
                     /locus_tag="VLL59_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HER6508408.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEVIDIKANPPKAQDLKH
                     WMETSGHTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGN
                     VLQVGYRKPYQELDLG"
     gene            complement(55400..56227)
                     /gene="xth"
                     /locus_tag="VLL59_000250"
     CDS             complement(55400..56227)
                     /gene="xth"
                     /locus_tag="VLL59_000250"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HER6508409.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            56462..57630
                     /gene="lctO"
                     /locus_tag="VLL59_000251"
                     /pseudo
     CDS             56462..57630
                     /gene="lctO"
                     /locus_tag="VLL59_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
     gene            57896..62842
                     /gene="scpC"
                     /locus_tag="VLL59_000252"
     CDS             57896..62842
                     /gene="scpC"
                     /locus_tag="VLL59_000252"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HER6508410.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMMTTTVAADELTTTSEP
                     TITNHAQQQAQHLTNTELSSAESQSPDTSQVTPETNREKEQPQGLVSEPTTTELADTD
                     AAPMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQ
                     SMRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDF
                     DEDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTK
                     YESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIE
                     DAVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDD
                     PLATNPDYGLVGSPSTGRTPTSVAAINSKWMIQRLMTVKELENRADLNHGKAIYSESV
                     DFKNIKDSLGYDKSHQFAYVKESTDAGYKAQDVKGKIALIERDPNKTYDEMIALAKKH
                     GALGVLIFNNKPGQSNRSMRLTANGMGIPSAFISYEFGKAMSQLNTNGTGSLVFDSVV
                     SKAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQI
                     AGASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLN
                     IDGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDP
                     QKGRFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTEQMPNGYYLEGFVR
                     FRDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVG
                     KHFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDN
                     NQDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTT
                     LLGTAFSGKSLTGAELPDGHYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFD
                     PETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQ
                     ADGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTK
                     ETLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFK
                     GLKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAVESTAWYGITARGSKVMPGDY
                     QYVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVR
                     EEVFYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVE
                     DRAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEY
                     YNNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATS
                     QITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYR
                     IEGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSA
                     TAKALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            63614..64321
                     /locus_tag="VLL59_000253"
     CDS             63614..64321
                     /locus_tag="VLL59_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HER6508411.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSFIL
                     TGIAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     TQEFYHIQTKIKPIKRT"
     gene            64561..66561
                     /gene="metG"
                     /locus_tag="VLL59_000254"
     CDS             64561..66561
                     /gene="metG"
                     /locus_tag="VLL59_000254"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HER6508412.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETAPWVLAKGDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKCYPNEQELVGKKLQIVA
                     NLKPRKMMKQYISQGMILSAEHGDQLTVLTVDPSVPNGSIIG"
     gene            67056..68069
                     /gene="nrdF"
                     /locus_tag="VLL59_000255"
     CDS             67056..68069
                     /gene="nrdF"
                     /locus_tag="VLL59_000255"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HER6508413.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAICFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            68073..68561
                     /gene="nrdI"
                     /locus_tag="VLL59_000256"
     CDS             68073..68561
                     /gene="nrdI"
                     /locus_tag="VLL59_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HER6508414.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            68528..70708
                     /gene="nrdE"
                     /locus_tag="VLL59_000257"
     CDS             68528..70708
                     /gene="nrdE"
                     /locus_tag="VLL59_000257"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HER6508415.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KQRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVEAGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEEAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(70870..71622)
                     /locus_tag="VLL59_000258"
     CDS             complement(70870..71622)
                     /locus_tag="VLL59_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HER6508416.1"
                     /translation="MLKKRYQLAIVLLLSCFSLVWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLVYPRAEQEAMAAYTCQQAALINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDHKKLHIEACFKGSL"
     gene            72081..72668
                     /locus_tag="VLL59_000259"
     CDS             72081..72668
                     /locus_tag="VLL59_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508417.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMARPVKAEGPERDRVEDQER
                     ENPYQKGLRDGNKAGYEQGKQDRQQKQNVSPDASPTPPDRDKVEVPEPGNNPYDKDDD
                     KQRYKNGWNIAYLSSYFNGWYSAERTDYPENTDDQSEERESDDSSQDDGRHQGSVDSS
                     SQQEDTDIISPVVETVLQAVLGVLSSFLSWLEKAI"
BASE COUNT        23137 a        13458 c        14947 g        21319 t
ORIGIN      
        1 caatagaaat tgactgaaaa ttcttagcac aaaaaatggt taagatatgt agctcattcg
       61 atttgacgaa tagatagaat tatattatta taaaaaacat gtaactttag taaggatgta
      121 acgtatgaaa aaaatatatg atttatgggt tagggttagt ctaatcaaaa aaataggtat
      181 cggtgttgta ataggagtca tgttgggcat tttggctcct gatcttacag gttttagtat
      241 tttaggaaag ttatttgttg gtggtttaaa ggctatcgca cctttgcttg tatttgcttt
      301 ggtttcccaa gccatctccc atcagaaaaa agggaaacag actaatatga cattaatcat
      361 tgttctgtat ttatttggta cctttgcgtc agctttagta gcagtactga cagcttatct
      421 attccctttg acgttagtgt taaatacacc tgtaaataca gaattatcac cacctcaggg
      481 tgttgctgaa gtttttcagt cacttctatt aaaattagtg gataatccga tcaatgcttt
      541 agctactgcc aattatattg gtgtgctatc atgggcaatt atttttggac tagcattaaa
      601 ggctgcaagt caagaaacaa agcatcttat aaaaacagcg gcagaagtta cttcacaaat
      661 agttgtttgg atcatcaatc tggcacctat tgggattatg agtctggtgt tcactacgat
      721 ttctgaaaac ggtgttggaa tcttatctga ttatgctttt ttgatactag ttttagtagg
      781 aacaatggtt tttgtcgcct tagtggttaa tccacttatt gcggttttga ttacacgaca
      841 aaatccttat ccccttgtct tgagatgttt acgtgagtca ggtcttacag catttttcac
      901 acgaagttct gcagccaata ttccagtcaa tatgcaatta tgccaaaaaa ttggattgag
      961 taaagatact tattcagtgt caattccact tggagcaact attaatatgg gtggggcagc
     1021 aattaccatc aatgtcctaa cgcttgctgc tgtacacact tttggtattc ctattgattt
     1081 tctaacagcc ctcttactta gcgttgttgc tgctgtctct gcttgtggtg cttctggtgt
     1141 tgctggggga tcgttgttac ttattcctgt agcatgtagt ttgtttggca tttcaaatga
     1201 tcttgcgatg caggtggttg gtgttggttt tattgttggt gttatccagg attcttgtga
     1261 gacagcctta aattcgtcaa ccgatgttct ttttacagct attgctgaaa atgctttttg
     1321 gaaacgtaaa aaagcctagc taggtttaac atagtaaaaa acatccttgg aaaacgccaa
     1381 ggatgttttt ttattattta agatagccaa gataatcaaa tttttcaaag gtgtggtcat
     1441 tagcgatggc cacaatgata gtattcggtt ctaaaggttc gaaaggtttg acattggtat
     1501 ctaaggtttt aacttctttt tgacgcatgc caatcacatt taactcatat ttacgacgaa
     1561 catctagttc ggaaagagat tgtccttccc agcttttagg aatgacaaat tcaatcatcg
     1621 aaataccatg ttccaaatag atgatgcttt cgatatgacg tcttaacaga tttgaagcta
     1681 cacgttttcc agaatcacgt tcaggggtga tgactttagt tgctccgatg ccatatagaa
     1741 cttcttcaaa aattttattt ttagccttgg caataatggt tggaacaccg agttttttac
     1801 agtgcatgac tgcaagaaca gaagattcca agttattccc tgaagcgata acgacagtat
     1861 cacaatgttc aatccctaca gctaatagaa attctttgtc agtaatatct ccaacagcgg
     1921 ctttagtgac caagtcggcc acctctttaa catgactttc tctgatatca atagcaataa
     1981 cgtcttgatc aaaattactt aattctctgg caacagtacg gccaaaaata ccaaggccaa
     2041 gaacgccgac agttttacgt tttaacatgt tttctcctta acccactaaa atatcagtag
     2101 tggcatattg aatggttttt tcttttcgtt gaatcagact gatgaggaca gtaattgggc
     2161 caacgcggcc gacgaacatc aagacaatga caataagacg tccagcagta gacaattgtg
     2221 gtgtcaaatc catagatacc ccaactgtcg cgatggcaga aatagattca aataagagtg
     2281 gtataggagc gatatgaggc tccacgctaa gtaataaaat aaaacctatc ataagaactg
     2341 caaaaaagaa gataagaact gtcatggtct gcttaattgt cttatttgcg ataattcggt
     2401 tacgaaaggt aacttctgat tgccctgaaa gttccgcttt aaagagtaag aaagtaatgg
     2461 cagcagtcgt cactttaata ccaccagctg ttccaccagg agcaccacca ataaccattt
     2521 gaatcatata aagaatgtta gtcggtgcta gggtatcgtt ataagagatt gttgcaaagc
     2581 cagctgttct catagtgact gtttgaaaaa atgaaaccat aagttgctga tgtaaactaa
     2641 aattggcaat ggttttgctg ttatcttttt ctaaaaacca ggttaagaag gttccaagaa
     2701 aaagaataac agctgtggtt tgtagtacta gacgagactg attggataat ttacgaaaag
     2761 ttgccccata acaatgaggt ctttcaaaaa agtatttttt aaaagctact cctaaatcaa
     2821 cccaaaccgc aaaaccaagt ccaccagaga taatcaagaa cgtaatgata acatttaatg
     2881 taggatttaa cataaagtct tttaaactag aagatcctaa attgtcaaaa ccagcgttac
     2941 aaaacgccga cacagctaga aaaatactat tgaagatacc atttttccac ccgaagcgag
     3001 ggataaagtc aatcatgata actatcgcag caaaggcttc tagactaaag gttactttat
     3061 aagcaaaaaa aaggtagtgc tttaaatctt tgctatcacc tcgatttaac gctgattgga
     3121 gcaaggtttg atcgctcaat cgcatttttc gcttgagggc aaaagtactc acagctatta
     3181 acgtcaccaa gccaagacca ccaatctgca ttagtgccat agcaatggtt tgtccgatac
     3241 cgttatacac ttcagcgacg ggaacaacag aaagtccagt cacacaaacc atggaaacca
     3301 cattaaagaa atgatcaaga tagacggtat taggaccatt ttgataatgg gtaaagggca
     3361 tggataacaa gagagtccca atcagaatca caatggcaaa actaaatgtt aagcgctgtg
     3421 tgactgaaag agatttgata aaagagcgtt tcatgtttcc tccagacata atatctccta
     3481 ctataataac aaaaataagt taaaaaagct aagtttcatc ttagcctttg gtactattta
     3541 tagaggtttt ttgttaggca agccagcttt tcttggatac ttgttaggcg tttccttttt
     3601 cttttcaaca atggtgatga agcgagaatc tccatttggc aattggtagc tatggttttt
     3661 aatgacttta ccaaaaagaa gacaaagagc attcttagct tcttctaact cttggtcagc
     3721 agcttgtgcc tttaaggcga ttaattttcc tccaattttt aaaaagggga tggttaattc
     3781 agatagaacc tgcatccgag caaccgctct ggcagtaacg acatcaaatt gacctcgaaa
     3841 ggccttgtcc tgtccgaaat cttctgctct accatgaaaa aaatggacat tttccaagcc
     3901 caattcctga gcaaggagtg tcagaaaaga aatccgctta ttaagagaat caataatggt
     3961 aacctcaagg tttgggaaaa gaattttcat gggtaggcta ggaaaaccag ctccagctcc
     4021 aatgtccaat aatttgattg gttcattagc taaaaagccc tgtaaaatag gagcgatgga
     4081 atcataaaaa tgcttgaggt aaacttcatt tttttctgta atagctgtta aattaatttt
     4141 agtgttccat tccactagta atttgaagta ggtgtcaaat tgctcttttt gcttcgatga
     4201 caataaaaaa ccatctttct ctagtgttcg gtaaaagtct tggggtgtca tttgtatcct
     4261 ctgtttttga tagttgttac cattttatca taaaatagcc tataacaaaa tccaataaat
     4321 catcagaaat aacacctcat tacttgctat tagcctagaa attgctataa ttgagacaca
     4381 aagattaaag gagacccact atgccaacag ttttgattat cttagtcgtt ttaggagtgc
     4441 ttgcgctatg gttaatgatt agttacaata gcctggttaa atctcggatg cacacaaaag
     4501 aagcttggag tcagattgat gtgcaattaa agcgtcgtaa tgacttgatt ccaaatctta
     4561 ttgaaaccgt aaagggatat gctagctacg agcaaaagac atttgaaaaa atcactgatt
     4621 tgcgtgcgcg tgttgcgaat gcctcaactc ctcaagaaac catggcggct tctaacgaat
     4681 tgagtaaaca agtgaccagt ttgtttgccg ttgctgaaaa ttacccagac ttaaaagcta
     4741 acgaaaactt cttgaaatta caagaagagt tgaccaatac ggaaaataaa atctcatatt
     4801 ctcgtcaact ctataattca acaacgtcta attacaacct tcaattagaa tctttcccaa
     4861 gcaatatcgc tggtaaatta tttggtttta aaccaagtga attcttacaa acaccagaag
     4921 ctgaaaaaga agttccaaaa gttgaattta acttttaaat atgaaattat catctagtag
     4981 gcaatcataa gagaaaggag aattatgctt tatcaacaga tttcacaaaa taagcaacga
     5041 acagttgttt tattaattat tttcttcgct ctcttagcac ttattggagc ttcagcaggc
     5101 tatctgctgt tagataatta tgccatgggc ttggttcttg ctcttgtcat tggggtgatt
     5161 tatgctacca gtatgatttt tcaatccacc agtcttgtaa tgagtatgaa caatgctaga
     5221 gaagttacag aaaaagaggc tccaggcttc ttccatattg tcgaggatat ggctatggtg
     5281 gcccagattc cgatgccgag agtttttatt attgaagatc cttctttaaa tgcttttgcg
     5341 acaggatcta gccctcaaaa tgctgctgtt gcagcaacga caggtttact tgaagtcatg
     5401 aatcgtgaag aacttgaagg tgttatcggc catgaaatta gccacatccg aaattatgat
     5461 atccgtattt cgactattgc tgtagctttg gcgagtgctg ttaccgttat ttctagtatc
     5521 ggtgggcgta tgctatggta tggtggtggt tctcgcaggc aaagagatga cggagatgat
     5581 gatgttttaa gaatcattac attacttttg tcgttattat ctttgctttt agcgccccta
     5641 gtagcaagtt tgattcagtt ggctatttct cgtcaaagag aatatctagc tgatgctagt
     5701 tctgttgaac taacaagaaa tccccaaggt atgattaagg ctcttgaaaa attgcagtta
     5761 tctcagccaa tgaagcatcc tgttgatgat gctagtgcgg ccttgtatat taatgagcct
     5821 cgcaaaaaaa ggagcttcag ttcattattc agcacccatc ctcctattga ggagaggatt
     5881 gaaaggttaa aaaacatgtg agcgtttggg gtttttgctc aagcctcact tttttatgtc
     5941 tttgggcaga taatctaaaa tggcaggaat tatcaaaaat atctgaacaa aaagaaaaaa
     6001 atgagtgaaa caatggttaa aaatagaatg atttaaatct taaaattaaa aaacgtcaga
     6061 aaataaatgc aaaactattg acaaatcttt tagatagtag taaaaataaa tgagagtttt
     6121 attaggagaa gatgatgtta gctatttccg aaatcagaaa acacccagac ggtctctcgt
     6181 ttgatcgttt atgtgatgtc aaaagtatgt tacttgagcg tgaccaacag attattgaca
     6241 taaaggcagt taaagctgtc ggtaatgttc gctatgataa ggggctttat ctgttagatt
     6301 atcaattgag ttacgaagtg atattaccgt ctagccgttc tatggttccg gtctgtttaa
     6361 gtgaagtcca acacattcaa gaattattta tagaggcgac agatttagct gataagaaag
     6421 agttggttga agacaatctg gtattagttt tagacaaaga cgctattaac ctcgaagaaa
     6481 gtattgtgga taatatctta cttgctattc cgctacaggt cttgacagag gaagaaaaga
     6541 aatcaaaaga gttgccagca ggtcaaaatt gggcagtttt gacagaagaa gactaccagt
     6601 gtctaaaaga agaaaagcaa aaagaaaata atccttttgc tagcttgcaa gggttgtttg
     6661 atgaataaaa ctgaatatta aagatgtctg taatttttat ttgaaaaaac agctattctt
     6721 tgatatactc tttagagaat atggttactt atctaaagta gaaggtattt tgaccataga
     6781 gggcaaagaa ggtaatgact attagatgct tcatatttta ttcgctagaa gactatttga
     6841 ccattagaac tgaaatagtc taggatatga gatggatttc atagttttct ttctgggaga
     6901 aaaagataga ttaagaggat aagggttggt ataaatgaca aagaaaattt taattattga
     6961 agatgaaaag aatctggcta gattcgtttc tcttgagctg caacatgagg gttatgaagt
     7021 cattgttgag gtcaatggtc gcgaagggtt agaaactgct ttggaaaaag agtttgattt
     7081 aatcctgctt gacttaatgt taccagagat ggatggtttt gaagtgaccc gtcgtttgca
     7141 aaccgaaaaa acaacgtata tcatgatgat gactgcgcgt gattctatta tggatgtggt
     7201 tgcaggttta gaccgcggtg cagacgacta tattgttaaa ccgtttgcca ttgaagaact
     7261 acttgcccgt attcgtgcta ttttccgccg tcaagatatt gaatctgaga agaaagtgcc
     7321 tagtcaaggc atttatcgag atctagtttt aaatccacaa aaccgttcag ttaatcgtgg
     7381 cgacgatgag atttctctca ctaaacgtga atatgatttg cttaatattt tgatgactaa
     7441 tatgaatcgt gtcatgacac gtgaagaatt attgtcaaat gtttggaaat atgatgaagc
     7501 tgttgagact aatgttgtag atgtctatat tcgttatctc cgcggcaaaa ttgatattcc
     7561 aggtaaggaa tcttatatcc aaacagtgcg tggcatggga tacgttattc gtgagaaata
     7621 agtcatatgg aaaatcagaa acaaaaacag aagaaatata aaaactcgtt accaaaacga
     7681 ctatctaata tcttttttgt tctttttttc tgcattttct ctgcctttac actgattgcc
     7741 tatagttcaa caaactattt cttattgaag aaagaaaagc agtcagtctt tcaagctgta
     7801 aatattgtta gagttcgtct ttctgaggtg gactctaatt ttacattaga gaacttagca
     7861 gaagttttgt acaaaaacga taaaacacat ctgagaattg atgacagaaa gggcagtcga
     7921 gtcattagaa gtgagcgcga tatcacaaat actctagatg cgaatcaaga tatttatgtc
     7981 tataacattg ataaacagat gatttttacc acagataacg aagaatcatc tcctggcttg
     8041 catggtccta tcggtcgggt gtatcacgac catatcgaag atcagtatcg tgggttttcc
     8101 atgacacaaa aggtatattc taatcggact ggaaaatttg tgggctatgt tcaagtcttt
     8161 catgatttag gcaattatta tgtcattaga gcaagactgc tgttttggct actagttgtt
     8221 gagttatttg gcacaagctt agcctattta atcatcttaa ttactacgcg gcgctttttg
     8281 aagcctttac acaatttaca tgaagtgatg cgtaatatct ctgaaaatcc taataattta
     8341 aacctgcgct cagatatttc gtcaggagat gaaatcgaag aattgtccgt tatctttgac
     8401 aatatgttag acaaattgga gacacatact aagttgcaat cacgttttat tagtgatgtc
     8461 agccatgaat tacgaacacc ggttgcgatt attaaagggc atattggtct cttacaacgt
     8521 tggggtaaag atgacagtga tattcttgaa gaaagcttga cagcaacagc gcatgaggct
     8581 gaccgtatgg caatcatgat taatgatatg ttagacatga ttcgcgtaca aggctcattt
     8641 gagggacatc aaaatgatat gacagttttg gaagattcta ttgaaactgt tgttggtaat
     8701 tttagagttt taagagaaga ttttatcttt acatggcagt cagaaaatcc aaaaacgata
     8761 gcccgtattt ataaaaatca ttttgagcag gctttgatga ttctgattga caatgctgtg
     8821 aagtattccc gtaaagaaaa gaaaatcgcg attaaccttt cagtgactgg caaacaagaa
     8881 gctattgtta gagttcaaga taaaggcgaa ggaatttcta aagaagatat tgaacatatc
     8941 tttgaacgct tttatagaac ggataaatca cgtaatcgaa caagtaccca ggctggatta
     9001 gggattggct tgtctattct caagcaaatt gtagatgggt atcatttaca gatgaaggtt
     9061 gaaagtgaat taaatgaagg ttcagtgttt atcttacata ttcctttggc ccagtctaaa
     9121 gagagttaga gtagcttaag gcattgttaa tgtgacaggt atagtatgta atcattagat
     9181 aatagtagca gtcttttgcc acaactggtt agaagctgat gctatttttt tagcaatgat
     9241 ggatgacatg aaagaaatac tgtcaatcgc gatgcctttt gttatccttg agaatatggt
     9301 aaaatagtgt attagattaa tttgatagaa ttggggtgtt tgcgtgcgtt gtccaaaatg
     9361 taattaccat aaatcgagtg ttgttgacag tagacaagct gaagacggca acaccattcg
     9421 tcgtcgaaga gaatgtgaac agtgtcatac tcgctttact acctttgagc gtgttgaaga
     9481 actcccttta ttagtcatca aaaaagatgg cacacgagag caattttcta gagataaaat
     9541 attaaatggg gttgtccaaa gtgcgcaaaa acgacctgtc tcgagcacag atattgaaaa
     9601 tgtcatttct cgtattgaac aagaagttcg aacaacctac gaaaatgaag tgtcaagtac
     9661 tgctattggt aatttagtga tggatgagtt ggccgaactc gatgaaatca catatgtacg
     9721 ctttgctagt gtctacaaga gcttcaagga cgttgatgaa atcgaagaac ttttgcaaca
     9781 aattacgaat cgcgtacgcg gaaagaaaaa acgtttaaat aatgatgaaa ccaattgata
     9841 cttttacata tctaaaacgc aacaaagtaa ctcttgattc ggtgacttta atacagttgt
     9901 actttccaat tattggaagt gacgcagtct ctatctatca atactttatt cacttttttg
     9961 acgatggttt acaacgtcat aaattcagcg atattttaaa tcacctacag tttggtatga
    10021 aacgttttga agatgctctt gccatattga cagcaatgga attagtgagt gtgtatcagc
    10081 tatcagatac atatctcatt acgttgcacc agccgcttag ccgtgacttg ttttttcaac
    10141 atccagctta ttctcgatta ttagaacaaa agattggaga ggtagctgtc tctgagttgc
    10201 aggtaactgt cccaagtcaa gcaagaaata tttctaagcg attttcggat atttttgggg
    10261 tgcaagaaaa tttgacgaac gtacctcaaa agccacaaaa gaattttgac ctttcaagtt
    10321 tccagcaatt aatggttcgt gatgggttac aatttgaaga taatcaaaaa gatatcatta
    10381 gcctttacag tattgctgaa cagtatgata tgacgtggtt tgatacttat caaatagcta
    10441 aggcgacggc tgttaatgga aaaattcgac ctgaacgctt attggctaaa aaaaatcaaa
    10501 gtatgacaaa accaagcaaa gaaaattttt cacaggctga gcaaattatt ttgcgagaag
    10561 caaagcaaga cagtgcttta gtctttttgg aaaaaattaa aaaggctaga cgtgcaacga
    10621 ttactaagga tgaacgcatt ttattgcaaa cattggccaa aatgaatttt cttgatgatg
    10681 ttatcaatgt catggtgctt tataccttta ataagacaaa atctgctaat ttacagaaga
    10741 gttatgtctt aaaaatggcc aatgattttg cctaccaaaa ggtgtcaacg gctgaagaag
    10801 ctatagtggt tttgcgagcc ttcacggatc gtcaaagttg tcggcaatca aaagtaaaaa
    10861 caagtcaaag caatgtgcct aagtggagca atcctgatta ccaagagaca acaagtcaag
    10921 aagagcaggc gaaactagat cagttcaaac aggctgcttt gaagaggtta gaaaacctag
    10981 gaaaaggggg tgactagatg gaaaagattg gagaaaccat ggcgaaattg ggtcaaaaca
    11041 ctcgtgttaa tagcgaccag ttgattcaaa ccattttagc ggatcctgaa gtagcaagct
    11101 tcatcagtca acatcactta tctcaagagc aaattaacct tagcttatct aagttcaatc
    11161 aatttttggt ggaacgccag aagtatcaac tcaaagatcc ctcttatatt gctaagggct
    11221 atcagcctat tctagctatg aatgagggct acgctgatgt gtcttatttg gaaaccaaag
    11281 aattggtaga agctcaaaaa caggcagcta tctctgaacg gattcaactg gttagtttgc
    11341 caaaatccta tcgccatatt catttatcag atattgatgt taataatgcg agccgtatgg
    11401 aagccttctc tgctatttta gattttgtgg aacaataccc atcagcagag caaaaaggct
    11461 tatatttgta cggagatatg ggaattggca agtcttactt gttggctgct atggcccatg
    11521 aattgtctga gaaaaaaggt gtgtcaacga cccttctaca ttttccgagc tttgccattg
    11581 atgtaaaaaa tgccatttca aacggctctg ttaaagaaga aatcgatgcg gtcaaaaatg
    11641 taccagtgct cattttagat gatattggtg cagagcaagc cacttcttgg gtccgtgatg
    11701 aggtgttgca ggtgatttta caataccgta tgttagagga attgccaacc ttctttacct
    11761 ctaattacag ctttgcggat ttggagcgaa aatgggcaac catcaaagga agtgacgaaa
    11821 cttggcaggc caaacgtgtc atggaacgcg tgcgttattt ggctagagag tttcatttag
    11881 aaggggctaa ccgccgttaa gtttgagata gcaatcaaga agaatagcta cacgtatgag
    11941 tgagtgaaag aaaaggagaa tcatggtttt acctaccgtt gccattgtgg gccgtccaaa
    12001 cgtgggcaag tccaccttat ttaatcgaat cgcaggagag cgcatttcaa ttgtagaaga
    12061 cgttgaaggg gttactcgtg accgtattta tgctactggg gagtggctta accgccaatt
    12121 ttcattgatt gatacaggtg gtattgatga cgttgatgcc ccgtttatgg agcaaatcaa
    12181 gcaccaggct caaattgcca tggaagaagc tgatgttatc gtttttgttg tttctggcaa
    12241 agaaggggtt acggatgcag atgaatatgt gtctaaaatc ctataccgaa ccaatactcc
    12301 agtgatttta gctgtcaaca aagtggataa tcctgaaatg cgtaatgaca tttatgattt
    12361 ttattcactt ggtttagggg atccctatcc agtttcttct gttcatggta tcggaacagg
    12421 ggatgtcttg gatgcgatcg ttgaaaactt gccagtagaa gaggctgaag aaaatgatga
    12481 tattattcgc ttcagtttaa tcggtcgtcc taatgttggg aaatctagct tgattaacgc
    12541 tattttaggt gaggaccgtg ttatcgctag ccctgtcgca gggacaacac gtgacgctat
    12601 tgacacgcat tttacggatg ctgacggtca agaatttacc atgattgaca cggctggaat
    12661 gcgcaaatct ggcaagattt acgaaaatac agagaaatat tctgtcatgc gtgccatgcg
    12721 tgccattgac cgctccgatg tggtcttgat ggttatcaat gctgaagaag gtatccgtga
    12781 atacgacaag cgtatcgctg gctttgcaca cgaagctggt aaaggaatga ttatcgtggt
    12841 taacaaatgg gataccattg acaaggataa tcataccgtt gctaagtggg aagccgatat
    12901 tcgtgaccaa ttccaatttt tgacatacgc tccgattatt tttgtgtcag ctttgacgaa
    12961 gcagcgcctc aacaaattgc ctgacttgat taaacgtatc agtgagagtc agaataaacg
    13021 tatcccatct gctgtcctca atgatgttat catggatgct attgccatta atccaacgcc
    13081 aacggataag ggtaaacgtt tgaaaatttt ctatgccact caagtgtcag taaagccacc
    13141 aacatttgtc gtctttgtta acgaagaaga attgatgcac ttctcttatc tacgcttctt
    13201 ggaaaaccag attcgcgcag cctttacctt tgaagggaca ccgattcatc tgattgctcg
    13261 caaacggaaa taagaaatga acatcaacta aaatgctgac ctaagaaata atctcatcat
    13321 tgataaggac tgtgttgtgt atgttacagg agacagtcct ttttataata cctttaaggg
    13381 tgtagacgga agattagtag caaacaaaga aaaaggattt tgacaagaaa tatcagtcgg
    13441 tttttgctat aatgaaagga taagcaaaaa ggtggaaaaa tgatggctag attaattcca
    13501 ggacgagtaa ggaatgaagg tattaagctt tatgagcaag gtttagtctc attccaagat
    13561 gataataaag gcattcttca aatagaagtg gagacttatc aggttcaata tggagcagat
    13621 gatgaggata tcacttgtca atgcgacaca tttcatatga aacagtattg caagcatatt
    13681 gcagcagtcg agtatttttt aaaaaatgat caaaaaggta agcttttttt aaaacagtta
    13741 acaaatcaaa caaaaatcaa agaaacaaca aagaaaatga catcttttgg tagtctcttt
    13801 ttagatagct tagccatgaa tgaagatgat tctgttaaat acaggctgtc tgctcttggt
    13861 agtcgaagcc ctttttcgtc agattactgg tggagtctga aaatcaatcg tttaccagat
    13921 gatcgttctt atgtgattcg agatattaaa agctttttgc agcttattaa aaaagaaggc
    13981 ttttatcaga ttggaaaaaa ttattttgaa caactttcat ggctgcagtt tgacccatcc
    14041 agtcaagacc ttattgagtt tttatggcgc ttagcatcta atactgacaa aggggacaac
    14101 gagaacattt ttccaaatca tgcaaggcat ttgcgcttac ctagtggttt ttttgaagaa
    14161 ggtattcact atttgacgtc actttatgac tttacttttg aggggccttc tcaaacttat
    14221 catcatcttt ttgtccgttc tttggaagca gaggcaggcc tttatgagtt taaagtggaa
    14281 gtgcatcgca aatctattga attgcaaatt gctgaaaaaa atgtgcaata cctctttgat
    14341 aatgactatc ttctttatca agataccttt tatcacttga cgttaaagca acgaaaaatg
    14401 gttcaggcta ttcgtagtct gcccattgag gccgacttgg ctaaacatat tcattttgat
    14461 ttggatgatc atgcgaaatt agctgcaagc ttatcagatt ttaaacagat cggtctagta
    14521 gaggctccta aaagctttgc tattagagac tttgaggtga cttttcaatt tgatttgtta
    14581 aatcgagatg aaatcagttg tcagcttatg tttgattatg gcaattacca agttagtgac
    14641 aaagcaagtt tagaagcact tccttttgct agtcatttaa aaaaagaaga aaaaatcaat
    14701 cgttctttac ttgcttttgg cttctcgcca caattttact caaaaaagcg actaacaagt
    14761 gcaaaagagc tctatacttt ttttgaagaa acagttccat gttttgagcg cttaggtaat
    14821 gttgcgttga gtacagctat ccaagcatta caagtgaaag aaatgcccaa gatcgctatt
    14881 agacgcaatc agggattact agatatttcg tttgattttt caaccattat tgaaaatgat
    14941 attgaccaag ctgttacagc tctttttcaa aataatcctt attttgtgag tcaaacaggt
    15001 caattagtgg tttttgatga tgaaactcaa aaagttagca aaagtttaca agaattaaga
    15061 gcaagacagc taaaaaatgg tcacttgcaa ctggatggca ttagagctct acaagtatcc
    15121 aaactttttg aaggcatgac atctgttcat ttttcaaagg aattagaaga gttagcctat
    15181 catttgcagc atcctgaaac tttttcaata aaaccgttac cagttaaggc tcaaatgcga
    15241 gattatcaac gcaacggtgt tcagtggtta tcaatgctca atcattatgg ctttggtggc
    15301 attttagcag atgacatggg acttggaaaa actctccaga cacttgcttt tttagctagt
    15361 cacctgaaat cagatagtaa agtgctcatt ttatctccat ctagtcttat ctataattgg
    15421 tttgatgaat gtcaaaaatt cacacctcag ctagatgttg tagtttctta cggacttaaa
    15481 caaatcagag atcaaatcat cgaagaaggt catcaaataa ccataaccag ctattcctcc
    15541 tttagacagg attttgagac ctatcaagcg tttcactacg attatcttat cttagatgaa
    15601 gctcaagtga taaaaaatgc gcaaactaag atttcacact gtttacgtgc atttaataca
    15661 gccaattgtt ttgcgctttc gggcactcct attgaaaata aaatgcttga aatttggtcc
    15721 attttccaaa ttgttttgcc agggttgcta ccgactaaaa aagagttttt aaaattaaca
    15781 gctgagcaag tatcgcgcta tatcaaaccc tttgtgatgc gtcgtaaaaa agaagatgtc
    15841 ctaccagaat tacctgattt aattgaaact aattattcaa acgagatgac agatgaacaa
    15901 aaagctattt acttagcgca gttaaggcag atgaaagatc aaattcgaaa ttctagtgat
    15961 gtggatatta gccgtcaaaa aattgagatt ttatctggta tcactcgatt gaggcaaatc
    16021 tgtgacactc caagtctctt tatggattac caaggcaaaa gtggtaagct agatagtttg
    16081 cgaatcttat tgacacaaat taaagaaaat ggtcatcggg ctttgatttt ttctcaattt
    16141 agagggatgc tggacttggc caagcaagag atgactgctc taggattgac ctcttatcaa
    16201 atgacgggat ctacccctgc caatgaacgt caagaaatga ctagagcctt taataacggt
    16261 tccaaggatg cttttttgat ttccctcaag gcaggtggag ttggaatcaa ccttacggga
    16321 gcagacacag tgattttaat cgatttatgg tggaatcctg ctgttgaaat gcaggcaatc
    16381 agtcgcgcct accgtattgg tcaaaaagaa aacgttgaag tatatcgctt aatcactcga
    16441 gggacgattg aagaaaagat tttagagctt caagaaagta agcgcaattt ggtgactaca
    16501 gttttggatg gcaatgaaag ccgagcaagt atgtccattg aagaaataaa agaaattttg
    16561 gggctaaaca ctcattaatc ttccttgatt ttagtgacat taaaaaccct ttaaagaaga
    16621 tgacaccaaa agcaccttat ataacctcgt taaaacgctt ctttttgaaa tatctttatt
    16681 gatatagcga ttgtcatttg ctagtaatga ttaaaacatt tagaaaaaga caagtcatag
    16741 aatcatcaag gaatgctttg aaaaataaca gtatttaagt tataatagag gatgctacaa
    16801 gaagggagaa tcaaaaaagg atggtaaaaa atcagtttcc tttagttgca gatggcattg
    16861 ctattagtga tccagcaaag caaatggctc tgtatgaaaa tgaagatctc attaccaaca
    16921 tccgtggcta ttaccaggac aaggagtatg atgatattgc tagaaatgag gagtttactg
    16981 ctaaagcaac ttctcggcag gccccttcta gtaagcgctt ttgtagcaat gatgaaaaac
    17041 accattatgt caaagaggcg cgtcaaaaag caaagcaaga tctcaaggaa aaaagacagg
    17101 cttatcttgc caaagaaatg gcctatgttc ctaaacaggt ttctaaaaag caacagcctg
    17161 cggattcttc tccttctcaa aagcaagcaa caacagaaat gagtcgtttt acaaaaaagc
    17221 ttcatcaaga caactatatt ttagctgagt tgccaaaaga atataaagag ccaaaaaatc
    17281 ttcctcaaca aggaactaca aaaaaaaata attacgattt tttaaaatcc agtcaaattt
    17341 acaataataa agaaatgaga caacaacgag aaaaaacaat tgcgcaagag cttaatctta
    17401 gtaggtttga ggatcttcct taataaatct actcagcgta tgcagatgac aaaggagtta
    17461 agatgtcaaa aacgtatcat tttatcggaa ttaaagggtc aggaatgagt gccttggccc
    17521 ttatgttgca tcaaatgggg cataaggtgc aaggtagtga tgttgaaaaa tactatttca
    17581 ctcaaagagg attggaacaa gcgggcatca ctatcttacc ttttagcgag gacaacatta
    17641 cgccagatat ggaacttatc gttgggaatg cctttcgtga aaacaacaaa gaagtggcct
    17701 atgctttgag acatcagatt cctttcaaac gttatcatga ctttttaggt gattttatga
    17761 aatcatttat cagttttgca gtagcaggtg ctcatggtaa aacttctaca acgggtttat
    17821 tgtcacatgt cttgaaaaat atcacagaca catcttattt aattggtgat ggtactgggc
    17881 gtggatctgc taatgcacag tattttgttt ttgaatcaga cgaatacgaa cgccatttta
    17941 tgccttatca cccagaatac tctatcatta ctaatattga ttttgaccat cctgattatt
    18001 tcacaggaat tgctgatgtg cgaaacgctt tcaacgatta tgctaagcag gtcaagaaag
    18061 ctttgtttgt ttatggtgaa gatgacgaac taaaaaagat cgaagcacct gcacctattt
    18121 actattatgg ttttgaagag ggcaatgatt ttatcgctta cgacattacg cgtactacga
    18181 acggatcgga ctttaaggta aaacaccaag gagaggtcat tggtcagttt cacgtacctg
    18241 cttatggaaa acataacatt ttaaacgcta cagcagtaat tgcaaacttg tttgtagccg
    18301 gcattgatat ggctctagtg gcagaccatc ttaaaacttt ttcaggtgtg aaacgtcgtt
    18361 ttacagagaa aattatcaat gacactatta ttattgatga ctttgctcat catccaaccg
    18421 aaattgtggc aacaattgat gcggctagac aaaaataccc aagtaaagaa attgtagcaa
    18481 tatttcagcc acatactttt actcgcacta ttgccttatt agaggatttt gcttgtgctt
    18541 taaatgaagc tgacagtgtt tatttagccc agatttatgg ttctgcacgt gaagtagata
    18601 aaggtgaagt taaggttgaa gatttggctg ctaagattat caaaccatca caagtagtaa
    18661 cggtggaaaa tgtctctcct cttcttgatc acgataatgc tgtttatgtt tttatgggag
    18721 ctggagatat tcagctatat gaacattctt ttgaggaatt acttgcaaat ttaactaaaa
    18781 ataaccaata acatgtcctg ccttaggcag gttttctcat tctaaaggag tttgatatgt
    18841 tgattagaca ggttcaagga tccgatttgg aagttattgc taccattgaa agtgacaatt
    18901 tttcaccaca agaagcaacg acaagagcag ttcttgaaga gcgcatacgg ctgataccag
    18961 atactttttt agtggcactt atcgatcagg aaattgttgg ctatatcgaa ggtccagttg
    19021 tcactactcc tattttggag gattctttgt tccacggggt gactaaaaat cctaaaactg
    19081 gaggctatat tgctattact agtttgtcca tagctaaaca ttttcagcaa caaggggttg
    19141 ggacagcttt gttggcggca ctaaaagatt tagtagtagc gcagcaaaga acaggtctta
    19201 ttttgacttg tcatgattac ttgatttcct attatgaaat gaatgggttt attaaccaag
    19261 gaatttcaga gtctcaacat ggtggaaccc tttggtacca aatgatttgg aaactttaga
    19321 atcacagctg attcaactgt tggtttgtta aaaataagta acaaatgcat catttaattg
    19381 caattaggat acttttaagt tataatggcg gttgattata tttaggagga ttggctttga
    19441 ccgattttaa ggataaagac caacaagatc agcagcgaag ctttaaagag cagattcttg
    19501 ctgagttgga aaaagcaaat caaatcagaa aagaaaaaga ggaagaactt tttcaaaaag
    19561 agttggaagc taaagaagca gctaagagaa cggcccagct atatgctgaa tataaaagac
    19621 aagatgcttt tcaaaaagag tctatagcac ataacaataa gacagctaaa cactttcaag
    19681 ctataaaagg tgcggtaatg acttcagaag cgcttaaacc gactttactt tctgaaaaag
    19741 aaaactcatc tttaaaaacg acaaataaga gagtcgtgca ggcaaatgag cttcaagaga
    19801 ctgcctctaa agaatctcaa gtaccgttaa ctattgagaa aggtcattca gtgagacgaa
    19861 aattaagcaa acgccaacag actgagcgag ctgctaaaaa gatttcaacc gttttgatta
    19921 gttctattat tataaccctt ttggctgtta ctctagcagg agcaggctat gtttatagtg
    19981 ctttaaatcc tgttgataaa aatagtgatg cctttgttca agttgagata ccatctgggt
    20041 caggcaataa attgattggt caaattcttc aaaaaaaagg tttaatcaag aatagcactg
    20101 tttttagttt ttatacaaaa tttaaaaact ttacaaattt tcagagcggg tattacaatc
    20161 tgcaaaaaag tatgagtcta gaagaaattg ctagtgcttt acaagaaggt ggtacagcag
    20221 aacctaccaa gccatctctt gggaagatct tgattccaga aggatacacg attaaacaaa
    20281 tagctaaagc tgttgagcat aatagcaagg gaaagaccaa aaaagctaaa acacctttta
    20341 acgagaagga ttttttggat ttagtcacag atgaggcttt tattcaagat atggtaaaaa
    20401 gatatccaaa attattagca actatcccaa ctaaagaaaa agctatttac cgtttggaag
    20461 gttacctttt cccagcaacc tataactatt acaaagaaac taccatgaga gaacttgtag
    20521 aggacatgct ggcagctatg gatgctactt tggtacccta ttatgataaa attgctgcta
    20581 gtggtaagac agtcaacgag gtattgacct tggcctcttt ggttgaaaaa gaaggttcaa
    20641 cagacgatga cagacgtcaa attgcaagtg tcttttataa ccgccttaat agcggaatgg
    20701 cactacaatc taatatagct attttgtatg cgatggggaa acttggtgag aaaacaacct
    20761 tggctgagga tgctactatt gacaccacca ttaattctcc ttataatatt tataccaata
    20821 caggtctgat gcctggtcca gttgctagct cgggggtttc tgcaattgaa gcaaccctaa
    20881 atccagcctc aacggattat ttatactttg tggccaatgt ccatactggt gaagtttact
    20941 atgcaaaaac atttgaagaa cactctgcaa atgttgaaaa atatgtgaat agtcaaattc
    21001 agtaaacaca aacatggtgc ttaagcacca tgtttgtgtt tctgattcgt tcaaaaaaga
    21061 aaagagagaa aacaattatg gcagaaaaaa cgtatccgat gaccctaacg gaaaaagaac
    21121 aacttgaaaa agaacttgaa gaattaaaac ttgtgcgtcg tccagaaata gtggagcgta
    21181 ttaaaattgc acgttcgtat ggagatcttt cagagaactc tgaatacgat gccgcaaaag
    21241 atgagcaagc ttttgttgaa ggtcaaattt caacgcttga aactaagatt cgctatgctg
    21301 aaatcattga cagtgatgct gttgcaaaag atgaagtcgc tatcggaaaa acagttatcg
    21361 ttcaagaagt tggaacaaca gataaagata cctatcatat tgtaggtgct gctggagcag
    21421 atatcttctc aggaaaaatt tcaaatgaaa gcccgattgc tcaagctttg attggtaaaa
    21481 aaacaggtga caaggttaga attgaatcac cagcagctac ttatgatgtt gaaatcatca
    21541 gcgttgaaaa gacaaattaa tcagatgaag ccattatttg cctaaccact aagtgttttg
    21601 gttgctaatg gcttttctag tatcttcaaa tgaggttgac tgttaggaag gtcaagtatt
    21661 aatcgcattg attatgagcc aagaggacta tagatcaaag atcgttttcg atggttattt
    21721 aatgccaaaa gaaaagacca gcaccttaat gtactgaccc caaaaagttg gacactatat
    21781 tttaaggaag tgtatgatct aaggaaactg acactaatga ttgaccgttt tgcaagactt
    21841 tattaatgat ttcttgcttt attttaaatg aataagtctg atacgtttcc ttccttaaca
    21901 ctatcgactc catactgacc catcagtcaa acggtatatc tcaaacgact acggtttact
    21961 ccaaattgat tggctagttg aggccaagaa acacctgatt ttttttaatg ctaaatttct
    22021 agcttatctt catagcttaa tttcatacaa aaacacccca atcgttagat ttttttgata
    22081 tgtccccttt cactagatga gtccagtaaa agggggcata tcgttttttg tctaactttt
    22141 ggggtgcagt tcataattgt gctaggtttt ttgtctttct taacgctttc gctgttttcc
    22201 agcattacga ttggatttta tttttttagg caagttagcc tgttccatgt tttgtgaagg
    22261 cgtaacgtcc ttacgagaag aagttgattg gtatgcttta ggcgggtttt tagcgtattc
    22321 ttctttaatt tgcttatgca atcgaggttt taagaggtag gttgtgatta actgttgaat
    22381 aatactaaag aaaccaccaa ctagccagta aagaccaaca ccagcaggga gtgagaagga
    22441 catgaagatc atcatgatag gcatggtgta catcatcgtc ttcatttgct cacgttgttc
    22501 ttctgaaacg gccatcattg ataaccatga ttggaagaag taaagagcag cgataattgc
    22561 tgttagcact aaactacggc taccaagatc aatacccata aaggtgcttg ttgatactcc
    22621 tttagtgtat tgagcggcaa aatacatggc agaaaagaat ggcatctgga tgagaagagg
    22681 tagacatcca atacctccaa gaggattaat cccatgagca cgctgagcag ccattaattc
    22741 tgtttgggca gccatttttt cttcctgact acttgcctgt ttgatacgtt tgttgattgg
    22801 ttcaaaaaca ggtttcaaga aggccatttt ctcagattga taacttgctt tccaagattg
    22861 atatagacct agtggtaaga taagtgttct aacaataatg gttacgatga tgatagccag
    22921 tccataacct agtccagcat tgtttgcaaa gtaatcgata aagtatgaca tgggttttcc
    22981 aagaaattcc caaatcatac ctttgggatt tccgtgagcg tctcttccca cacagcctgt
    23041 caaggtgaat agaattgaca gtgctagtcc tgaaaagagg atgcgattta atgttagttt
    23101 caatgtgttt atcctttaat tttaatatac ttatctattt tacagttttt ttcagaaatt
    23161 cacaatagtt ctgaaggccg atttttactt gcctatttga aagtcctgaa agtcttcaaa
    23221 attagccatg gtgacatcca cataagtgac ttttgcccat ttggatggtc ctttacgaac
    23281 ttcttgaata aatgtggcta ttttatctga atcttttgat tgggccagga tttcaacggt
    23341 cccatcgttg atattccaga cacgaccata aatatctcct atatctagag ctaaagtatg
    23401 ggtagcgtat cgaaaaccaa caccttgtac acgtccagaa acaattaaac gtactttttg
    23461 cataagaagg gcctccttgc ttttattata gcacatactt agcaggaaat ctctttagct
    23521 aattgtctac ttcctgtcac ttttactaaa gacaagaata caaaaatgag atagttagta
    23581 gtactaacag taaaagaggt ttgtctattt taaaaatagt atcaaaaaaa ggtcttttag
    23641 gtttaaaaca ttgaactgcc cccaaattga ccatctaaga agttgatgct ttcaaatgct
    23701 gtcgcgtatg gtataatagg cgcatggtta ttacatcaaa aacaaatcaa ctaattaagc
    23761 aaacaaaaaa attattgcaa aaaaagcatc gaaaacagtc ctatttgatt gagggctggc
    23821 acctttttga agaagcccaa aaatcaggac aagtttttcg ccacatcttt gttttagagg
    23881 aaatggtgga gcgtctagca ggtgagcaag aactcgttat tgttagccca caagtgctca
    23941 aggagttgac cgactctcct agtccacaag gcattgttgc tgaggtggag atacctaagt
    24001 tagcctttcc atcagattac aaagggaaat atttggtttt agaggacgtc caagacccag
    24061 gaaatcttgg gaccatcatt cgtacagcag acgctgcacg gtttgatggg gtctttcttt
    24121 ctgaaaaatc agcagatatt tacaaccaaa aaaccctacg ttccatgcaa ggtagccatt
    24181 ttcatttacc aatttggcga acagatgtct atcagctttg tcgagagctc caagagtata
    24241 aaactcccat cctagcaaca actctgtcaa agaaatctgt tgactataaa agcctcacac
    24301 atcatgaaag gttggctttg gtgttgggaa atgaaggcca gggcattagt gctgaaatgg
    24361 cagccctagc agaccaactg gttcatatta caatgcctgg tcaggcggaa agtttgaatg
    24421 ttgccgtagc agcaggaatc ctcattttca gcttgattta agctaatatg atataataac
    24481 caagtgaggt aattatgtta tgcattatac agaagataaa gaatatatgg aacacgtcgg
    24541 tcatttgatc gctcatcctc gctttcaaaa attgagtcat attgttcagc accaacattc
    24601 aacgcgtctt gaacattcta tcaatgtttc ttattccagt tataaattag ccaagcgatt
    24661 tggttgggat gctaaaagta cagccagagg gggcttactt catgatttct tttattatga
    24721 ttggcgcgtg accaagttta ataagggtca tgcctgggtt catcctcgta ttgctgtacg
    24781 aaatgcgaaa aagttaacag aactcaataa aaaagaagag gatatcattc taaaacacat
    24841 gtggggagcg accattgctt ttccgcgtta caaggaaagt tatattgtga caatggtaga
    24901 taaatactgg gctgtcaagg aagcagtgac gcctttgaga caaaaatggt ctaatcgacg
    24961 gtttcttcgc cgcaagaccc tccaaagtca taatcgttaa gtaaaggagt tattatgaac
    25021 gatcacgtta tttatacaca atcagatgtg ggattaaatc agttttttgc taaaatttat
    25081 agtctagtgg gaatgggagt gggtttgtct gcttttgttt cttatttgat gctttatcca
    25141 tttagagaaa atttaatctc tattcttgtt aatcagccga tgatttacta tggtgctgcg
    25201 attattgaac ttattttagt ttttgtagcc agtggtgcag cacgaaaaaa cacaccagct
    25261 gcattgccca tttttcttat ctattctgcg ctaaatggct ttaccctaag ctttattatt
    25321 gtggcatacg ctcaaacgac agtttttcaa gcatttcttt cttcagcagc tgtgtttttt
    25381 gccatgtcaa tcattggtgt caagactaaa cgggatatgt caggtcttag aaaggctatg
    25441 tttgctgctt tgattggtgt tgttgtggct agtctgatta atctttttat tggtagtggg
    25501 atgatgagtt atgtcattag tgtgatttcc gtgctaattt tctcaggtct catcgcatca
    25561 gataatcaaa tgattaagcg cgtttatcaa gcaacaaatg gccaggttgg tgatggctgg
    25621 gctgttgcta tggccttaag cttgtattta gattttatta acttatttat cagccttctt
    25681 cgtatttttg gaagaaatga ttaacattaa aaagtgagta taactactca ctttttaatg
    25741 ttaacaggat aagtaaactg taaggaagaa attcgagata gatataagat gaggctgcta
    25801 aaagacctag tgttaatttg taaactcttt ctttttttgg tatactatta aggattaaat
    25861 acgaggagaa tatagataga tatgtcaaca gctatttgga ttttattact tattgttgcc
    25921 cttggggtag gtgtttttgg tgggattttt attgcccgta aacaaattga aaaagaaatt
    25981 ggtgaacacc cacgtttaac accagaagct atccgtgaaa tgatgagcca gatggggcaa
    26041 aaaccaagtg aagcaaaaat ccaacaaact tatcgtaata tcatcaaaca atcaaaagca
    26101 gccgtatcca aaggcaaaaa ataaaagcta attgttatag gggaaacctt tgtgatagtt
    26161 agaagtgaac agtctttgat ctcaatgttc agtagcactt gtcttatcag ttagatttgt
    26221 caactgttca gggtttaaaa agaaactcag ttggctattt ccaactgagt ttttcatatc
    26281 gtcagtaagg aagtaaacat aatggataca agaccaattg ggtttttaga ttctggtgtg
    26341 ggaggtctga ccgtcgtttg tgaattgatt cgtcagctcc ctcatgagaa gattgtatat
    26401 attggtgatt cagcaagagc cccctatggt cctagaccca aaaaacaaat taaggagtat
    26461 acttgggagc tagtcaattt tttgctgact caaaatgtta aaatgattgt ttttgcatgc
    26521 aataccgcaa cagcggtggc ttgggaagaa gtaaaagcag ctttagatat tcctgtttta
    26581 ggggttgtct taccgggggc aagcgcagct attaaatcaa cgacaaaagg ccaggttggg
    26641 gtcatcggaa ccccaatgac agtggcttca gacatttatc gcaaaaaaat ccagctatta
    26701 gcaccatcta ttcaagtaag gagtcttgct tgcccgaagt ttgtaccgat tgtggaatca
    26761 aatgagatgt gttcgagtat agctaaaaaa atagtttatg acagtctatc accattagtc
    26821 ggtaaaatag atacccttgt actaggatgt actcactatc ccttgttacg accaattatc
    26881 caaaatgtta tggggccatc tgttaagctg attgacagtg gagcagaatg cgtccgagat
    26941 atctctgtct tattaaacta ttttgacatt aacggtaatt atcatcaaaa agctgtcgaa
    27001 caccgctttt ttacaacagc aaatcctgag atttttcaag aaattgcctc gatttggctg
    27061 aaacaaaaaa taaatgtgga gcatgtcacc ttatgagtga aaaaatttac gaatacaaag
    27121 atgaaaataa ctggtttatc ggaaagatga ctggtcataa tttaatatcg ggctggggag
    27181 tcaaacacac gacaatcaaa aaaatagatg accttttaga cggtattgcc gcaacgttag
    27241 attgggaaaa tcctaaaggt tacgatgttt cggtggtgcg ttatcagtct cctttatctc
    27301 tcatcacctt tattatcgac atgataaatc aagagaccca gcgtaagatt aaggtaactc
    27361 cccatgcagg cacgatttta ttaatggaaa atgcgaaact gcttgcagtt tatctcccag
    27421 aaggtggagt ttcaacggct acattttttg cgactagtga acagggattt ggggatactg
    27481 ttttaatcgc tacacgaaac gagggaaaaa ccaaagagtt ccgcaatctg tttggccagc
    27541 taggttatcg tgtggaaaat ctcaatgatt atccagaatt gccagaagtg gcagaaactg
    27601 gtactacttt tgaagaaaat gctcgcttga aagcagaaac gatttcacgc ctcacaggaa
    27661 aaatggtatt agcagacgat tcaggactaa aagttgatgc cttgggtggt ttacctgggg
    27721 tttggtcagc tcgtttctca ggaccagatg ccacagatgc caagaataat gccaaactct
    27781 taaacgaatt agctatggtg tttgaccaaa agaagcgctc agctcaattt catacgactt
    27841 tggtagtggc tgctcccaat aaagatagtt tggttgtgga agccgagtgg ccaggctata
    27901 ttgctacgca gcctaaggga gaaaatggtt ttgggtatga ccctgtcttt atcgtcggag
    27961 agactgggcg tcatgctgca gaattagagg ctgaccaaaa gaatcagttg tcgcatagag
    28021 gtcaagcagt tcgaaaatta atggaggtct ttccagcatg gcaagcaaaa caatcatagt
    28081 aatgagtgac tctcatggtg accgagatat cgttcaagcc attaaagaca agtatcttgg
    28141 tcaagttgat gctattttcc ataatgggga ttctgaatta aacagctcag atcctatttg
    28201 ggctggtatt tatgtcgttg gcggtaattg tgactatgat acaggttacc ctgatcgttt
    28261 agtaactcga ttaggcacag ttacgattgc ccagacacat ggtcacttgt accatattaa
    28321 tttcacttgg gataaactgg actactttgc tcaagaagta gcagcagata tttgtctata
    28381 tggacaccta caccgtccag ctgcttggca agttgggcaa accctcttta tgaatcccgg
    28441 atcagtaaca caacctcgcg gagaaattaa cgagaaatta tatgctcgtg ttgaactaac
    28501 tgatactcaa attaaagttg attactttac aagagatcat aaactttacc catcactgtc
    28561 taaggaattt aaacgatgat cgcaaaagaa tttgaaacat ttttaatgag tcatttagat
    28621 aattatctta tcccggaaca agacttggct atttttatcg acacacataa tgcagaccat
    28681 gtgatgttac tattggtgag caatggtttt tctagagttc ctgttatcac acgggagaaa
    28741 aaatatgtgg gaaccattag catctcagat attatgatgt accaatctaa aaggcagctg
    28801 acagattggg aaatgagtca aacagatatt ggcgagatgg ttaataccaa aattgaaacc
    28861 attagtatta cttctagcct aacagaaatt atgcacaagt taattgattt cccattctta
    28921 ccggttgtag atagagcgaa tcgctttgtt gggattatta cgcgaaaatc tatattaaag
    28981 gctgtcaaca gtcttttaca tgattttaca gatgattaca cgattataaa aaaatgaaga
    29041 gttatattga accttttatt gctagcaagg ctttatctca aaatagtcaa aaagcttatc
    29101 gatacgattt gcaacagttt tgtcaactgg ttggtgaacg tgtcaatcaa gataaactat
    29161 tactttatca aaatagcata gctaacctaa gtttatctgc aaaaaaacgc aaattatcaa
    29221 cagctaatca attcttatat tacttgtatc aaataaagta tttaaatagc tattttcgat
    29281 taacagatac catgaaagcg atgcggactg agaagcagca agctgctatt attaatactg
    29341 atattttcta tcaaaaaacc ccttttgtgt gggggcaatt aatcagctta ttaatattgg
    29401 agctgggttt aactccgagt gaagtagctg gtattgaagt agctaacttg gatttaaatt
    29461 ttcaaatgtt gacgctaaag actaaaaaag gtgtgcgtgt attacctttg tcgcaaatac
    29521 taatcccttt tttagaacaa caactcgttg gcaaagaagt ctatcttttt gaacatcgag
    29581 gcatcccttt ttcaagacaa tggtttttta atcacctaaa aacctttgtt cgaagtattg
    29641 gttatgaagg attaactgct caaaaattac gagagcaatt tattttgaaa gaaaaactag
    29701 ctggtaaatc gataatagaa cttagcgata ttcttgggct gaaaagccct gtgaccttag
    29761 aaaaatacta caaatcataa tggatataaa acttaaagat tttgaaggtc ctcttgattt
    29821 actcttgcac ttggtatcac agtacaaagt tgacatctac gaggttccta ttgttgaggt
    29881 tattgagcag taccttaatt atattgaaac cttacaggta atgaaacttg aagtggctgg
    29941 tgactacatg ctgatggcaa gtcagctcat gttaatcaaa agtagaaggc tattaccaaa
    30001 ggtggtagaa cacatcgaag aagatttaga acaagatctg ttagaaaaga tcgaagaata
    30061 tagtcgcttt aaagcagtta gtcaagcgtt agcgaagcaa catgaccaaa gggcaaaatg
    30121 gtattcaaaa cctaaacaag aattaatttt tgaagatgct atcttacagg aagataaaac
    30181 ggtgatggat ctatttctag ctttttcaaa cataatggca gctaaaagag caattttaaa
    30241 aaacaaccat acagtcatcg agcgtgatga ttataagatt gaagacatga tggcttctat
    30301 caaacagcga ctggaaaaag aaaacgttat tagcttatca gcgatttttg aggaatgcca
    30361 aacattaaat gaagttatca gtatattttt agctagtcta gaattgatta agcttcacgt
    30421 ggtatttgta gagcagctct ctaattttgg ggctatcata ctacgaaagg agaagaaatg
    30481 acgtatttgt cacagataga agcgctgcta tttgttgcag gtgaagaagg attaagtttg
    30541 cgacatctag cgtctatgtt atcattaacg ccaacagctc ttcaacagca attagaaaaa
    30601 ctctctcaaa agtatgaaaa agatcaacat tctagtcttt gcttgataga aacagctaat
    30661 acctacaggc tagtaactaa agaaggtttt gcagaactct tgtgtgctta tgccaaaaca
    30721 ccaatgaacc aaagtttatc tcgtgcgagt ttagaggtct tgtctattgt tgcatacaaa
    30781 caacctatta cacgaataga aattgatgac attcgagggg taaactccag tggagctttg
    30841 agtaaattat tggcatttga tctcattaga gaagctggca aaaaagatgt ggttgggcgt
    30901 cctcatttgt atgcgacaac agattatttt ctggactata tgggaattaa tcatttagac
    30961 gaattgattg aagtatctgc cgttgaacca gcagatgaag agattgctct ttttaggaca
    31021 caagactgag ttttgcttgt catcaaatag caaatgacgt ttacaaaagg atttgtttta
    31081 aggcgtttta gttgaaaaag ccttaaacta agaacaacaa aaagttgctc aaaagaaaga
    31141 agaatataat gcgaattaac aaatacattg cccatgcggg tattgccagt cgacgtaagg
    31201 ttgaagaatt gattaagcaa ggcttagtaa ccttaaatgg tcaggttatt acggatttag
    31261 caaccactgt aaaatcggga gacgtggttg aaatagaagg aagtcctatt tacaacgagg
    31321 aaaaggttta ctatttgctt aataaacctc gtggcgctat ctcaagtgtg tcagatgaca
    31381 aaggccgtaa aacggtactg gatttactac ctcaggttaa agaacgcata taccctgttg
    31441 gacgattgga ttgggacaca tcaggggtcc ttattttaac gaatgatggt gattttacag
    31501 atactatgat tcatcctaga aatgaaatag acaaggttta tctggcgcgt gtcaaaggaa
    31561 ttgcaacgaa agaaaatctt cgtcccttaa ctcgaggaat tgttattgat ggtaaaaaga
    31621 ccaaaccagc tcgctacaat attgttcgtg tagaagctga taagaatcga tcgatcgtag
    31681 aattgactat ccatgaaggg cgaaaccatc aagtgaaaaa aatgtttgag tctgtggggc
    31741 ttttggttga taaattatct cgtacacgtt ttgggaccgt cgacttaaag ggactaagac
    31801 caggagaagc aagacgctta aataaaaaag aaataagtca actgcataac ttagctaata
    31861 cgaaaaaatg atgaaaaaac tattaatagt atctgttaaa gcttatcaaa aatacatttc
    31921 tcctttatct cctcctagtt gtcgctacaa gccaacctgt tcagcttata tgttaactgc
    31981 tattgaaaaa catggtacta agggaatatt aatggggata gcaagaatat taagatgtca
    32041 cccttttgtt gctggtggtg tcgatcctgt tccagaagat tttagcctaa tgagaaataa
    32101 aaatacgtct aaaaacgctg aaaaggcatg actttatcaa aaaatggctt gacattgata
    32161 gatgaagtgt tataatggaa aacaagcatt cgttggttta aatcaaacct gttatgattt
    32221 aagttagcga gtcaccatca accacattgt ttgctgagca tgactccgag cagtgtggtt
    32281 ttttaaatta aaaagagtaa atgagattat gacgacaaaa gaacttatca acaaaaacga
    32341 caaagtaaaa aaggctcgca atcatattgt cctgtttcaa ccccaaattc cacaaaatac
    32401 tggtaatatt gctagaacat gtgctgcaac taatgcacct ttacatatta ttaaacccat
    32461 gggatttcct attgatgacc gcaaaatgaa gcgtgccggc ttggattact gggacaagtt
    32521 agaactgcat ttttatgatc atttagaaca gtttatcaat caatgtcacg gacagcttca
    32581 cctgattagc aagtttgcag ttaataatta ttctcaagct acttatgctg atggcgattc
    32641 ccattatttc ttgtttggac gagaagatac aggcctgcca gaagatttta tgcgagaaca
    32701 tgctgaaaaa gcacttcgta ttccgatgaa tgatgagcat gtacggagtt taaatgtctc
    32761 aaatacggtt tgtatggtga tttatgaagc ccttagacaa cagggctttc aagggttaga
    32821 gttaaagcat acttacgaac acgataaact aaaataatgg actttttaaa agcgtcagtt
    32881 tttggcaaca tgcgttgtca gtagctgacg cttttaaaaa tttagtcaaa gctattgcta
    32941 tctaggttta aatctgctat gctagaagtg tcttcagggc agggtgtgat tcccgaccgg
    33001 cggtgactag gtaactagaa gtccgcgagc gcaagctgat gtggtgtaac tccacaaccg
    33061 acagtatagt ctggatgaga gaagaccggg ctttttgtgt aggcttattt tagctacaca
    33121 ataacgacgg aacttctttc aatttgaaaa aattggagga attttttaat gtcaaaaaca
    33181 cataaaatga ttatgattgg tatactttct gcgatatcat ttctattgat gctagttagc
    33241 tttgccatta ttccaggcgc agctttttta aaaattgaat ttagtattat tcctgtttta
    33301 tttggtttaa tgattatgga cttaaagagt gcttacttga ttttgttatt gaggtcctta
    33361 ttgaaactct ttttgaacaa tcgtggagtt aatgatttta ttggtctccc aatgaatatt
    33421 atcgctatcg ctttatttgt gacggctttt gccttagttt ggaaccgtca aaaaacgctt
    33481 agtcaatatg tatttgctag cttactaggc acagggttat taacgtttgg catggttgtt
    33541 ctcaattata cttttgccat tcctttatat gctatatttg caaatattga tatcagagct
    33601 tatattggtg ttactaagta tatgatgact atggttattc cgtttaatct tgttgaaggg
    33661 ttgatatttg caattacctt ttattttgtg tatattgcaa gtaaaccaat tttagaaaga
    33721 tacttacact aatatgatga caaacaaaca aactcacttt ttaatagctt cttttgcatt
    33781 gctaatcttt gttataatag gctatacggt caaatttttt cctgaacgtt tggcacttct
    33841 agataatact attcaagcag agattagagg caaccttcct atagtgctga cgcaattctt
    33901 taggggtgtt actgtatttg gaaatgtcat gacacaagtt ttgttagtta ttgtgtcggt
    33961 cctagtttta ttctttatga agtggaaaat tgaagccttg tttatcttat caaatggtgc
    34021 cattgcagca tttttgatta cgactctcaa gctcttttac caaagaccaa gacctgctat
    34081 tgagcatttg gtttatgctg gtggctattc gtttcccagt ggccatgcga tgggtagcat
    34141 gctgattttt ggtagcctat tgattatttg ttatcaaagg ctacattcaa aactattaca
    34201 atttgtgact agcatgatct ttataatact aattttagta attgggttat ctcgtattta
    34261 tctaggggta cactacccaa gtgatatttt agcaggcttt gtattaggat ttgggatttt
    34321 gcagtttatt tatccttttt ataagcaaaa acgatttgaa tggcgatttc ttttgaaaca
    34381 agactaattt ttcttgagaa gacatagggc ttatttaaat catttagaat aacattggca
    34441 agcatcaccc cttgattgcc agtgttattt tagttttagt tagatgatgt gagctgatga
    34501 ttagtaaata cgtttagata aaaaatgatt aaagtgctat gtaacgtcag aaaagacgtg
    34561 atttttgttg atctgtaatc attaagtaag ctgatgtaga agtagtgaat tctaatgact
    34621 gagctatctt ttgcatagat gactatcttg ctagtaatga tttgtgctac aatagaaaca
    34681 tgaaaaaaag atatcagaca ttaaacgagc attaccgtca actatttggc gcaaaaatgt
    34741 ttaaagttcc gattgatgcc ggctttgatt gtcccaatcg tgatggaacg gtagctcatg
    34801 gaggatgtac tttttgcaca gtatcaggtt ctggagatgc tattgtagca ccagatgctc
    34861 caattaaaga gcaattttat aaagaaattg attttatgca ccgtaaatgg cctgatgtca
    34921 atcgctattt ggtttatttt caaaacttta ccaatactca tgatacagtt gatgtgattc
    34981 gcgaccgtta cgaacaagct attaacgaac ctggagttgt tggcattaat attggcacac
    35041 ggcctgactg tctaccagat gataccattg cttacttagc agaattatca gaacgcatgc
    35101 atgtgacagt ggagctaggc ttacagacaa cttatgaaga aacttctagg ctgatcaaca
    35161 gagcacattc ttatgatttg tataaagaaa cggtgaggcg actaaggcat taccccaaca
    35221 ttaatattgt ctcgcacttg attaatggat tgccaaaaga aacccatgac atgatgcttg
    35281 aaaatgtgag acgctgtgta acagacaatg acattcaagg aattaaattg catttactgc
    35341 atttgatgac caatactaga atgcaaagag attatcatga aggacgctta aagttgttga
    35401 gtcaaaagga ctatgtttcg attatttgtg accagctaga gattatccct aagcatattg
    35461 tgattcaccg tattacagga gatgccccac gagatatgtt gattgggccc atgtggagtc
    35521 taaataagtg ggaagtattg aatgccattg ataaagaaat ggaaagacga ggaagctttc
    35581 agggctgtaa agttgactaa tttgtctcat tttgacggat ttggatagga gaaaagtgat
    35641 gctaaaacgc cccattcatc tctcgcatga ttttttagcg gaggttgtgg ataagtctag
    35701 tgtggttgtt gatgccacga tgggtaatgg aaatgatact gcctttttgg cacaattagc
    35761 taaaaaggtt tatgcttttg atgtgcaaga acaagctatt agaaaaacaa gtgagcggtt
    35821 agcacagcta ggattattga acgctgagct gattttagcg ggtcatgaag cggttgatca
    35881 gtatgtgaca gagccggtgc gcgcagcgat ttttaacctt ggttatttgc ccagcgcaga
    35941 taaatctatt attaccttac caaataccac actccaagct ttatcaaaac tgctaacgtt
    36001 attaatggta ggtggacgta ttgctattat ggtctattat gggcatgatg gaggcagttt
    36061 ggaaaaagat gctttattag attttgtcaa gcaattagac caaagaaagg tttctgcaat
    36121 gctttatcag cctcttaatc aggtgaatac cccacctttt ttaatcatgt tggagaaatt
    36181 agcagacgtt tagcccttat ccctgtgtca agtctactag aagttctgcg attatttcgg
    36241 tggaaaaaga agaaatccca taggctttgg ctataaatgt gatataatga agtcactata
    36301 ttattttttt aggagttaca ttaacatgga agaccctgtg agtcagccct tagtgattca
    36361 atttttattg ttagttgttt taaccttgtt aaatgctttt ttttcagcca gtgaaatggc
    36421 cttagtttct ctcaatcgtt ctcgggtgga acaaaaagca gcagacggtg ataaaaaata
    36481 cgctcgtttg ttgcgggttt tagaggaacc taatcatttt ttatcaacga ttcaagttgg
    36541 gattaccttt attagtttac tatcaggagc aagtttatca gcttctttgg gtaaggtgat
    36601 ctcaggttgg ctaggtaatt cagcgactgc aaggacagct ggtactatca tctccttggt
    36661 tttcttgact tatgtctcta ttgttttagg agaattgtat ccaaaacgga ttgccatgaa
    36721 cctcaaagac aagttggcga ttgtttcagc ccctattatc attgggttag ggagactggt
    36781 tagtcccttt gtatggctct tatcagcttc tactaattta ctgagccgac ttacccctat
    36841 gacctttgat gatgcagatg agcaaatgac acgtgatgaa atcgagtata tgttatcaaa
    36901 aagtgaggcg acccttgatg ctgaagaaat tgagatgttg caaggagttt tctcacttga
    36961 tgaaatgatg gcgcgtgaag tcatggtccc aaggaccgat gctttcatga ttgacattaa
    37021 cgatgatccg cttgaaaata ttcaggaaat cttaaaacaa agtttttcac gcattcctgt
    37081 ttatgatgtg gataaagata aaattatcgg tctcatccac actaagcgtc tcttggagtc
    37141 aggtttccgc cagggatttg atcagattaa catgcgaaaa atgttacaag aacctctttt
    37201 tgttcccgaa accatttttg tagatgatct cttacgccag ctgcgcaata cccaaaatca
    37261 gatggctatt ttgctagatg aatatggtgg tgtggcagga cttgtgactt tggaagactt
    37321 gcttgaagaa atcgtcggtg aaatcgatga tgaaaccgat aaagcagaac aatttgttca
    37381 tgagattgga gacaatacct atattgttgt tggtactatg actttaaatg agtttaatga
    37441 ctattttgat accgaactag aatcagatga tgtagatacc attgctggtt tttatttgac
    37501 aggtatcgga accattccaa gccaggagca aaaagaagcc tacgaaatag ataacaaaga
    37561 caaacattta gttctaatca acgataaagt caaagatggc cgtattacga aattaaaatt
    37621 aatcctgtct aatatagaac agattattga ggaagactag gctccatgcc tagtcttttt
    37681 gatgaaaagt gttataatga aaatgtaaaa acgtttacaa gtaatgaagg agatgcaatg
    37741 actgagaaag attatggaca agtaacaggg atggtgcatt cgacagaaag ttttggttct
    37801 gtagatggtc caggcattcg ttttatcatt ttcttgcaag gctgtaaatt acgttgccaa
    37861 tattgccata atccggatac ttgggagatg gaaaccaaca attcaaaaat cagaacagtc
    37921 aatgatgtct tgaaagaagc ccttcagtac aaacatttct ggggaaaaaa aggaggaatt
    37981 accgtatctg gtggtgaagc tatgcttcaa attgatttta tcactgcctt attcatcgaa
    38041 gctaaaaaat taggtatcca taccacacta gacacctgtg gctttaccta tagaccgaca
    38101 cctgaatacc atcaggttct tgataactta ttggcagtga ccgatttgat tttattggac
    38161 ttgaaagaaa ttgatgaaaa acaacataaa attgtcacgc gtcagcctaa taaaaacata
    38221 ttgcaatttg cgaggtattt atccgacaag cagattcctg tctggattcg acatgtcttg
    38281 gttccaggct tgactgatat tgatgatcat ttgacacgat tgggtgagtt tgtcaaaacc
    38341 ttgaaaaatg tcgataaatt tgaagttttg ccttaccata ccatgggaga attcaagtgg
    38401 cgtgagctag gtattcctta tcagttagaa ggtgttaaac caccaactaa ggaacgcgtt
    38461 caaaatgcca aaaacttgat gcaaaccgag tcttatacag aatacatgaa tcggattcat
    38521 cagtcataag agctgttata gggttgaggt ttcctcaact ttttaaaata ttataagcag
    38581 atcttttgta atcttccttt gattttaggg ggtaattttg ctaaaataaa atgaataaac
    38641 aaaatgaggt agaatgatta tgtcaaaaat tttagttttt ggtcatcaaa atcctgatac
    38701 ggatgctatt gcatcatctt atgcttttga ttacttatcc caaaaagcgt ttggtttgga
    38761 tactgaagtc gtagctttag gaacacctaa cgaagaaaca gcttttgccc ttgattattt
    38821 tggtgttgag gcaccacgtg tggtagagtc tgctaaagca caagggtctg aacaagtgat
    38881 tttgacagac cacaatgaat tccaacaatc cattgcagat atccgtgagg ttgaggtata
    38941 tggtgtggtt gatcaccacc gtgtggctaa ttttgaaact gcaaatcctt tatacatgcg
    39001 tgtggaacca gtaggatcag cctcatctat tgtttaccgt atgtttaaag aaaatggcat
    39061 cgaggtgcca aaagcgattg cagggatgct cttgtctggt ttgatttcag ataccttgtt
    39121 gttgaaatct ccaacaactc atgtgtctga tcaccttgtc gctgaagaat tggcagagct
    39181 agcagaagtg aacttggaag actatggaat ggctctttta aaagcaggta caaaccttgc
    39241 aagcaaatca gaagtagaat tgattggtat tgatgccaaa acatttgaat taaatggcaa
    39301 tgctgtgcgc gtggcacaag tgaacactgt tgacatttca gaagtcttag aacgtcaaga
    39361 agctattgaa gcagccatta aagatgccat ggctgcagaa ggttattcag actttgtttt
    39421 gatgatcacg gatattgtta actcaaactc tgaaattcta gctattggag caaacatgga
    39481 caaggttgaa gcagccttta acttcaccct tgataacaat catgccttct tagcaggtgc
    39541 cgtttctcgt aaaaaacaag tggttccaca attgacagaa agttttggag cttaatgaaa
    39601 agacgcttta aaaggacttg atttttttga ccaagtcctt ttgtcactct tctatgttat
    39661 aatagaaggt atgataacag tatttcattc agataaactc accagacaac ctttctttca
    39721 agaccttatc aattatctcg accagcatga tcacgttata ttacgagaga tcaaaaaagc
    39781 ctttcctaat gtgacaggta ttgacaaggc catcgaaagc tatgttcaag ctggctatat
    39841 tcgccgtgaa aataagcgtt atggcatcaa ccttcctttg gtgagttctg atcagcagct
    39901 ggccttagac actatgcttt ttgtggacac ctgttcagct atgtatgaaa atattttagc
    39961 ggttgttttt gagactcagt taacaaacca aaccaatcac gtgatgatca aggaaaagac
    40021 caacatcacg agagacgatt tgaccctggc taattatttt taccgcctca aaagaggtga
    40081 gaagccatca gctgagcaga tggacttgta tgacctcttg ggggatgtga atcaggaata
    40141 tgcccttaaa tatatgacaa cttttttgct taaattcacg cgcaaagacc ttgtgatgca
    40201 aaaacgtcct gatatatttg tggaagctct ggttacactt ggttacctaa aacaagtgga
    40261 gcctacaaca taccagctgc taatgacctt ggataaagaa agtttaacct ttatagcacc
    40321 atagaaaaga gctaggaata aggactgttc ttagcttttt gagtgctttt attttgtttt
    40381 tgccattaag taaagaaaat aaggggctcc gataagcgac actaaaatcc ctgtctggat
    40441 attagtgcca accagataga ctcgcccgac tgtatctgca acaagaagta ggatcattcc
    40501 gattaaaata ctaatgggta ttgttaattt atgattactc cctaccaagt atgtactaaa
    40561 gtgtccagct attaagccga taaaactaat attaccaacc aaaagaacac tcaaagcacc
    40621 taagccagct gctaagacaa gtatcaaacg acgcttacgg tttaaaggga gtcctagtcc
    40681 aatagcagta ttatcagcta atcccataat attaaggaaa tgggcttgac tataagtcaa
    40741 tagccaaaaa cacaataata aaggagcgat gacactcaga gtaggccagt cgtctcctat
    40801 taattggccg ctaagccaat tgatgaccaa atcgactttg tagcgattaa tatgaccaac
    40861 aagagcaacc attagacttg aaagcatggt agtaacagct acaccagtaa gaattaaccg
    40921 tgtaggatca atttgtcctt gttttgtcaa agatagccaa taaacgctaa aggttgttac
    40981 aacagcacca agcatggcaa ataaaggcaa gtaatggctg atatgagctt gctcaaagaa
    41041 agaaaaggag accacaatag ccaaagagat acctgctcct atagtaatac ctaatacacc
    41101 agagtcagct aagggatttc gtgttaaacg ttgtaataat agccctgata aagcaagaga
    41161 accgcctcct agacaagcag ctagaattct tggcagacga atgttaataa cgatgaaaga
    41221 tatggcatgg ctagattttc ccaaaaacac atggataagg tccaaaaaag atagatgaga
    41281 ttctccaagg gacaaagcta atcccataag acttacaagt agcaggatca ggctagtata
    41341 taaccccaaa aggtgtcggt gagatttcaa tagcggcctc ctcttcttat taaccataaa
    41401 aagcatggaa aaccaattaa gctaaccaat gccccaagag gggtttcata aggcggattg
    41461 agattacgac aagcaatatc aacccatacc atgaaactag cgccagaaac tgcacaaagc
    41521 ggcaaaaggt atcggtaatg atgaggtgta aagtgtttca taagatgagg aatgactaag
    41581 ccgataaaag aaatgcttcc agcaatggct acagctgctg atgataaaat aagaaccaaa
    41641 atcataaaga ctgcactgat caagttggtc ttttgcccaa gagcttttgc ctgagactca
    41701 cttagactaa ggacggtcag gtgataagat aatagctggg ctaaacaaag actaagaata
    41761 ataagaggag caatatagcc gatcatttgc caattgaccc cgacaagacc tcctgcttgc
    41821 cagccgataa cagcatttgc cagatgatag taattggtaa taccttgacc taatgctgat
    41881 agcagtatgg aaaccatagc tcctgctaag acaaggcgga gctgatggta gcctttgcca
    41941 gattgataag aaaggccaaa gactaaggtt gctgccaggc tagaccctaa caacgaaagc
    42001 agaataatga gggaatagtg caagtgaggt acaaacgcat aagccagtac caaggctagt
    42061 cctgctccag cattaatgcc taaaaggcca gactcagcga taggattacg tgtgattgct
    42121 tgcatgatag ttccagaaac agctaacgca gagccagtta aggtagcccc aaaaagtctc
    42181 ggtaatcgta tagctagtaa aacattggct ttatggccgt tttgctttcc aaataaaata
    42241 gagttaagat cctgatgtga taaagcaacg gctccaaagc gcagatgaca gtaaatagca
    42301 acacataagc taaaactaag tagcacaaag acaagccaaa agatatgtga cttagtgatt
    42361 atctgcgttt tttttaagca aaaacgctcg agacacaaaa agggatgctt agttttcact
    42421 tgataagatt gcctctcgta aagtttctaa ttgatattct aaagaaagag gatcagtaaa
    42481 gtaaaaaaca ttggcattga ctttgatcac atggtgtttt ttcacagctg gaatggattg
    42541 ccatagcttg ctttcatata gagcagaacc agtctcatca tcttctgcag caacgacgac
    42601 ataatcacca atatagtctg gcaagacttc ctgcgacaat gacaggtaac cttgtttaaa
    42661 aacttcagtc ttcacttttt caggagcatc ataatggaaa gcttgatgga taatctctcc
    42721 gccacgtccc cagtctttac caaaaaggta aacgtctttt tcataaagcc ccataatagt
    42781 aaaggttgct ttgtcacctg taacggcctt gacttctttt tcataagctg ctgttttagt
    42841 tttccaatct tttaaccatt tcttggcttt gtcttctttg ttaaagatgc ggccgaagtc
    42901 agataacact tgtaaataat cacgtttgcg gtattcaatc gaaataacag gcgcaatttc
    42961 tgccaattgt ttaatatttt cttctgtaga gccaacaaca atgaggtcag gcttaagcgt
    43021 tgtaatggct tctaaatcag ttgcagcaac ttgctttgct ttttttacag tctttgctaa
    43081 gatggggttt ttcttgtcat aagaagtaac cccgactaga ttcatatcta attttttgag
    43141 gtaaccagtg taagttgaag ccagactgac tactcgctta ggctgtttag gaatatctcc
    43201 gtaataagtc acaccagcaa tttgaggcat aggcgataaa ctttttgagg cggtgttaga
    43261 atgattagtt gcttgattac cacaggcgat taaggtaata gttgtcaaac agagtgttaa
    43321 tagtagagtt aattttttca tgtatgctaa ttctcctaga ataaagttat tgaagctgat
    43381 aagtcagcac tataggacag ttgtggatag gatcatcaac cagtaccggt ttgatttgga
    43441 agatgtcttg aatgataggt gaagtcataa catctgctat agtaccagta taatggatct
    43501 tgccatgttt catagcaatc agatgatccg aatagcgggc tgaaagattg aggtcgtgaa
    43561 gaaccataac aatagtcttg ccggcatcct tatttaggga tttaacgagc tctaggattt
    43621 ctagttgatg atttaaatct aaataagtag ttggctcatc taaaaaaata gtatcagtgc
    43681 cttgggctaa tgccattgca agccaaaccc tttgacgttg ccccccagaa agagcatcaa
    43741 caggttgatc agcataggcc atgacattgg tggcttgcat agcccaatga atggcttttt
    43801 tgtcagctgg actaagattt ccaaagtaag attgatgggg aaaacgtccg taagaaacca
    43861 attcgtaaac agttatgccg ttagttgctt cttgaacttg aggtaaaaga gctagttttt
    43921 tagcaacctc tttagtttct aatgtggcaa tgttttgccc atttaaatac acaactccct
    43981 gttttggtgg taataatctt gtcagtgctt ttaataaact agacttccca cagccattgg
    44041 cgccaataat ggtcgtaatt ttaccttcag gaatataaaa cgataattta tcgatgatgg
    44101 tacgctgttc ataggcaatt gtgaggtctt cagcactaat tgttgtcata tggttgcctc
    44161 ctttctaaaa agagtcaaag ggttgatgaa agtgcacatt aaagtgttta tctgctcatt
    44221 ttaaaatagt tgagaagtag cttattttct caaaatcttc actattatag catagaaaaa
    44281 aggcttaaca aagccttttt tgatgtgatt tttaggatgt attaaaaaag aaatattagt
    44341 ttagaatgat taaaaacaat agcgataatc attctaaact aacgtcaaca tactctagag
    44401 gtagtgtttg gcgattgcta aatcaccagc ataagctact tgttgtcctt taacaatttg
    44461 ataagcatct gcgcctttcc cagcgataat cacagcatct tttgctcctt ggcaaagaga
    44521 catggctttt tgaatagctt gctcgcggtc actaataatc tctactgggc gtgcgatatg
    44581 gctggcaatt tcttttgaaa tatcttctgg atcctcgaaa ttagggtcat cagcagtgag
    44641 aatgacggtg aggtttggat gctgatgaat caccctacca aaatcagctc gtctgctctc
    44701 gcctttattt cctggtgcac ctaaaatcaa cattaatttg cctgtctgat gttcttccac
    44761 aacgctgagt aatttttcta agctgtcacc attatgggca taatcaacaa aaactttagc
    44821 atgatttgtc atagtgagga cttccatacg gcctgggacg cgagtcttag cgataccttt
    44881 ttgaatatca gctaggctag cacccaaacg aaggcaggca agtccagctg ccatagcatt
    44941 ttcttggtta aaatggccaa ttaattgaat gtcataatgg ccagctaatt gtcctttagc
    45001 ttcaaaggag aaggcttggc tagtggtgat ctggttgtca gacaagggac cataaaacac
    45061 atgctcttga tccgctacct gatccgctag aaatgaaaaa tgatccatcc cgctattgat
    45121 cacaacagct ctgctattct ccattaaaag acgcttatga tagaaataat cttcaaacgt
    45181 tggatgctcg attgggccaa tatgatcagg actaatattt aggaaaaccc caacatcgaa
    45241 cgtaagccca tagacacggt caacgaggta agcctgacta gaaacttcca taatcaagtg
    45301 ggtcatgcca ttagtcatac actcagccat catagcaaaa agatccaagc tctcaggagt
    45361 tgtgagttgt gatttgaaaa aggtcttgcc atctaaggtg gtattcatgg tagaaaacat
    45421 ggcaggttta taggattctt tcaacatgtg gtaggcaaaa taagcagccg tcgtctttcc
    45481 cttagtacct gtaaaagcta gtagtttgag cttttcttga gggttgccat agaaagccat
    45541 ggcaattaga ctcatagctt ttttgatatc agtgaccaaa acaacgggaa taccaagctc
    45601 gtaatctacc tctgaaatat agagttgtaa tccgttagtg attgcttctt taaggtagtc
    45661 agctttgaaa gttgcccctt tagcaaaaaa aagggtcttg ccatctactt gacggctatc
    45721 gtaactcaag cgctcaaaac ttaagccttg ataatggtag tggtatccgt cggcatcaag
    45781 aacctcacga aaattatggt ctttttttaa aatgtctaat aattgttcaa tggttatcat
    45841 acccttattt tatccttaaa gttcttgttt tacaagtcac aagcaaaagt ttataataaa
    45901 gctaatagaa actaggaaag aatagatatg tcgacagaaa aaaaacaact gacacaagaa
    45961 gaattgatgg ttcagggagc agcctggtcc acagctggta atttcattag ccgacttttg
    46021 ggagtgttat acattattcc ctggtacatt tggatggggc aatacgcgat tcaagccaac
    46081 gctcttttca atatggggta taatgtttat gcttattttt tattgatttc aaccacagga
    46141 ctcaatgttg cgattgctaa gcaggttgcc aagtacaatt ccatgggaca aactgagcat
    46201 agctatcaat taatccgaag taccctaaaa ctcatgcttg gtctgggcct tattttttca
    46261 gccattatgt atctgggctc tcctttattt gcgagcttat ctggtggtga tgacacactt
    46321 gttcccatta tgcacagcct ttctttagca gtttttattt ttcctgtaat gagtgtgatt
    46381 cgaggtatct ttcaaggcca caataatatc aagccttatg cgattagcca gattgctgag
    46441 caactcattc gggttatctg gatgcttttg accaccttcc ttatcatgaa attaggttct
    46501 ggtgattacg cttcagcagt aactcagtca acttttgcag cctttatcgg gatggtggct
    46561 agtatgggtg ttctggggta ctatctttgg aaacagggac ttctagcagc tatttttagt
    46621 aagccagatc atactgtttc cattgatatc aagggcttgt tgcttgaaac attaaaagag
    46681 tctattccgt ttatcgtaac aggaagtgcc attcaagcct ttcaattgat tgatcaatgg
    46741 acttttgtca atacgatgac tctttttaca gattatagcc gttctcaatt gcttgtttta
    46801 tttggttact ttaacgcaaa cccagccaaa attacaatgg tcttaattgc agtagcagca
    46861 tctattggtg gtgtaggcat tgccttatta actgaaaatt atgtcaaaaa agacatgaaa
    46921 gcagctgctc gcttaatcat taacaacatt gaaatgttag tgatgttttt gttacccgct
    46981 cttactgggg caattatttt agcaagacct ctatattctg ttttttacgg agctagcgag
    47041 gatcgtgcca ttcacctctt tgtggcggtc ctcttccaaa ccttgttgat ggcgctttat
    47101 accctttttt caccgatgct tcaagctctt tttgaaaatc gaaaagcgat ttactacttt
    47161 gcttatggta tcttgattaa gttagtttta cagataccgc ttatttattt gctacatgct
    47221 tatggtcctt tactagcgac gacgattgct ttagtggtgc caatttattt gatgtatcga
    47281 cgcctatatc aggttactca ttttaaccgc aaattgttgc aaaaacgttt attattaacc
    47341 ttgattgaaa ccttattaat gggactggtc gtgtttgtgg ccaactggct attgggctat
    47401 gcctttaaac cgacaggccg cttgaccagc cttctttacc tcctcattat tggtggcttg
    47461 ggaatgacgg tttacacggc actcaccttg ctgacgcatc aactggataa attaattggt
    47521 agcaaagcta gtcgccttcg tcagaaatta ggctggcatt aatataatga caccaagaac
    47581 gatttcgtga gtgcttatcg aaatcgtttt ttttcttaat gatctcgctt agtaaaggta
    47641 gctgataaaa aatcaggatt tcccaagcaa actactgata tttttggtat aatgataaaa
    47701 gtgtaaaaaa atagaaggaa gtatatcaac atgggaaaat gtcaagttat ttcgcatccg
    47761 cttatccaac acaaactttc aatcttacgt cgtcaaacca catcaactaa agattttcgt
    47821 gagttggtta atgaaattgc gatgctgatg ggatatgaag tgtcacgcga ccttccctta
    47881 gaagatgtcg acatccaaac gccagtctca aaaacggtcc aaaaacagtt agctggtaaa
    47941 aaattagcta ttgttccgat tcttcgtgct ggtattggga tggttgatgg cttgttaagt
    48001 ttggtaccag ctgcaaaagt tggccatatc ggcatgtacc gtaatgaaga aacccttgaa
    48061 cctgttgaat acctcgttaa actaccagaa gatattaacc aacgacaaat tttccttgtt
    48121 gatccaatgt tggcaacagg tggctcggct atcttagcag tggattcgtt gaaaaaacgt
    48181 ggcgcagcaa atattaagtt tgtctgttta gttgcagcac cagaaggggt gaaaaaactt
    48241 caagaagctc atccagatat tgatatcttc acagcagcac ttgatgatca tttaaatgaa
    48301 catggctata tcgtgccagg cttgggcgat gctggtgatc gtttatttgg gacaaaataa
    48361 aagagacaac catcaaatag tagccttttt aggccaatcg ttcttgattt tgtttaaaaa
    48421 atcagagaga tttctcttct ttaaaggaaa agcaagttta tgatttgacc tttattgacc
    48481 aaaatattat aataaagaca atcagtaaaa aagagatgac ctagtgggtt gccgtctctc
    48541 aaaatgacgc tactaaaaac ccttgtagat tggagaatgt attatgattc ctgttgttat
    48601 tgaacaaact agccgtggag aacgttctta tgacatttat tcacgtttat taaaagaccg
    48661 tattatcatg ttaacagggc ctgtcgaaga caacatggcc aactctgtca tagcgcagct
    48721 cttattcctt gacgcgcaag acaacacgaa agatatctac ctatatgtca acacaccagg
    48781 tggctctgtc tcagcaggct tggctattgt cgataccatg aactttatca aggccgatgt
    48841 gcaaactatt gtcatgggta tggcagcttc tatggggaca gtcattgctt catcaggaac
    48901 aaaaggcaaa cgctttatgt taccaaatgc agagtatatg atccaccagc caatgggtgg
    48961 cacaggcggt ggcacgcaac aaacggatat ggctatcgca gcagaacatc tcttaaaaac
    49021 acgtcaccgt ttagaaaaaa tcttagcgca aaatgctgga aaaacgatta aacaaatcca
    49081 taaagatgct gagcgtgatt attggatgag tgctgaagaa accttggctt acggtttcat
    49141 tgatgaaatc atggaaaaca acgaactaaa ataaagagga tctctgcaaa agtattctag
    49201 aaacttctag gatgcttttt ctcttagaaa ggaaaataat gatacagcct actgcattaa
    49261 aacagcttca agagttaaaa cgtcagttca gatccctttg caaccaatta tgagatagtt
    49321 tgaggatgat ccttagcagc tgtgtgcaag aagttatgac gatttcataa aggatgacct
    49381 agccagtctt tcttcgtctc ttttacttaa agtgtggtat aatcagatta tgctagccaa
    49441 aactaaaaaa tgcattgcca ttaaaggtgt tgtagatcgg cttatcctag atctcataac
    49501 aatgctgtag taccgccctt accttgctac taaaggcgct gttgaagcac aaattgactt
    49561 gcaaaggatc ttgactgata ggtatatgtc cggtggaatc gctaaagcag caaaaaaacc
    49621 aagacccttc tttggtctct accaaaatat aatagaaaag gatttagaat gtttcaaaaa
    49681 caagaacgta ttggactcgt cgtttacctg tattataacc gagatgccag aaagttatca
    49741 aaatttggtg atttatatta ccattccaag cgctctcgtt acctcattat ttatattaat
    49801 aaaaatgatt tagacacaaa attagaagaa atgagacgtt tgaaatgtgt taaagacatt
    49861 agaccatcag cttttgatga tattgaccgc caatttgtag gtaaccttca tcgcgacgaa
    49921 acaaacaacc atcaaaaggg ttaacacccc cctagttact gattagcgtt tcagatttag
    49981 ttagcttatt aaagtaagaa ggttttgaca gatgctcaca ctacttcaag acaatgagac
    50041 aactagagca ttagtgaata actgagttga ctgtcacttc tttaataaga acggatagga
    50101 ttggtcctaa aatagagcac tgcaaagata tgccagtgct ttttagctca ttttttgata
    50161 aaatagaact actaaaaagt gaaggaaata agatgatcac aggaaaactc ataaccgttg
    50221 aaggtccaga tggcgcaggg aaaacgactg ttttagagca actcattcca ctgttaaaac
    50281 aaaaagtggc tcaggagatc ttgacaacaa gagagcctgg aggtgttgcc atttcagaat
    50341 acattagaga acttatttta gacatcaacc atactactat ggaccctaaa acagaactct
    50401 tactttatat tgcggctcga aggcagcatt tggtggaaaa ggtactacca gctcttgaag
    50461 caggccagtt ggtttttatt gatcgtttca tcgatagttc agtagcttat caaggtgcag
    50521 gacgcggttt gatcaaagca gacattcagt ggctcaacga gttcgcaaca gatggtttag
    50581 agcctgactt gaccctttat tttgatgttc cttctgaaat tggtttagca cggattaacg
    50641 cgaaccaaca aagagaagtc aatcgtttag atttggaaac aatagagata catcaacgag
    50701 tacgaaaagg atacctagcc ttagctaagg agcatccaaa acgtattgtc acaattgatg
    50761 cgactaaacc attgaaagaa gttgtctctg tcgctttgga acatgtctta gccttgcttt
    50821 tagcctagaa taagggaggg taggaatgga tttagcgcaa aaagctccta acgtttatca
    50881 agcttttcag acgattttaa agaaagaccg tctgaatcat gcttatcttt tttcgggtga
    50941 ttttgctaat gaagaaatgg ctcttttttt agctaaggtc atcttttgtg aacagaaaaa
    51001 ggatcagacg ccctgcgggc attgtcgctc ttgtcaattg attgaacaag gagattttgc
    51061 cgatgtgacg gtattggaac caacagggca agtgattaaa acggatgtgg tcaaagaaat
    51121 gatggctaac ttttctcaga caggatatga aaacaaacga caagttttta ttatcaaaga
    51181 ttgtgacaaa atgcatacca atgccgctaa tagcttgcta aaatacattg aggagcctca
    51241 gggagaagct tacatatttt tattgaccaa tgatgataac aaagtgcttc cgaccattaa
    51301 aagtcggaca caggtttttc agtttcctaa aaacgaagcc tatctttacc aattggcaca
    51361 agaaaaggga ttattaaacc atcaggctaa gttagtagcc aaacttgcca caaataccag
    51421 tcatctagaa cgtctgttgc aaacgagcaa gcttttagaa ctgataactc aaacagagcg
    51481 ttttgtatct atttggctga aagatcagtt gcaggcatat ttagcgttga accgtctggt
    51541 acagttagca actgaaaaag aagaacaaga tttagttttg acccttttga ccttgctctt
    51601 ggcaagagag cgtgcgcaaa cgcctttgac acaatgggag gctgtctatc aggctaggct
    51661 catgtggcag agcaatgtta attttcaaaa cacattagaa tatatggtga tgtcagaata
    51721 agtgcaattg gaattcgtta tggggaaacg aagcttgtca aaagacttgc ccgtagcgac
    51781 caaagtagcg gcgcataggg gcaaaacaag cttttgaaga aaatactgcc tttgcaacag
    51841 atttgatgaa agaagtatca cgattaataa cacaaaatca acttaaaatg acgtttatta
    51901 atagtgtctt tcccttagat cagcatgttg tcctaattcc cttttcagca gaagagcaca
    51961 tggattttta caactgttaa aagatttagc ggccgatttt aggtcaagaa gtgagctgcc
    52021 ccagattaac agccaagaag atttcatttt ctatggaggc tatggaccgt gtggcaggcc
    52081 actgtgctgc tttcgttttt gggaaaattt ctgacagtat ctattaaaat actaaaaaat
    52141 caagggttat cattgacttt gggtaaagca acaagctctt atggccgttt gctttgctgt
    52201 ctctatgatg aaggtggctt ttaccaataa agcaagaaaa aattccctga atatggtacc
    52261 atagtagaga caagtgatgg ccctgcaaca gtagcagcct tgatatattt acagatccca
    52321 ttaaggtgcg gttaaaagac cagttgacct tagtcactta tgctttagag gaggttaaag
    52381 taggtgaata aaaaagaatt attcgatgct tttgatggat tttcccaaaa tttaatggtt
    52441 actttagctg aaattgaagc catgaaaaaa caagtccaat cactagtaga agaaaacacg
    52501 attcttcgcc tagaaaatac aaaactacgg gaacgtttga gtcacctaga acatgaaacg
    52561 gtagctaaaa atccttccaa acaaaggaag gatcacttag agggaattta tgatgaaggg
    52621 tttcatatct gcaatttttt ctatggacaa cgtcgtgaaa atgatgaaga atgtatgttt
    52681 tgcagagaat tattagatag aaagtaaggg catgcaggtt caaaaaagtt ttaaagacaa
    52741 aaaaacaagc ggaaccttgt atttggttcc aaccccaatt ggcaatctgc aggacatgac
    52801 ctttagagca gtggcaacgt taaaagaggt tgattttatt tgtgcagaag acacaagaaa
    52861 cacaggtctt ttgctaaaac actttgacat tgctaccaag caaatcagct ttcatgagca
    52921 caacgcctat gagaagattc ctgatttaat tgatttatta atatcaggac ggtcactagc
    52981 tcaggtgtct gatgcaggaa tgccatcgat ttctgatcct gggcatgatt tggtcaaggc
    53041 tgctattgat agtgatatcg cagtcgttgc tttaccaggt gcctcagcag ggattacagc
    53101 tttgattgct agtggactgg ctcctcaacc ccatgttttt tatgggtttt tacccagaaa
    53161 agcagggcaa caaaaggctt tctttgagga caaacaccat tacccagaga cacaaatgtt
    53221 ttatgaatca ccctatcgca tcaaagatac cctgaccaat atgttggctt gttatggtga
    53281 tcgtcaagtg gtgtttgtta gagaattaac caagcttttt gaggagtacc aacgggggtc
    53341 gatttcagaa atcttgtcct accttgaaga aacaccccta aaaggggagt gtctgctgat
    53401 tgtggctgga gcccaagtag acagtgaggt tgagctgaca gctgatgttg acttagtgtc
    53461 tctagtgcaa aaagaaatcc aagcaggagc caagccaaat caggctatta aaacaattgc
    53521 taaagcttac caggtaaatc gccaagagct ttaccaacaa tttcatgact tataagtcat
    53581 cgtagattag gagaaaaaca aatgacagaa gatcaagcaa ctatccttat tttaggagta
    53641 tacggaatca tattggctat attcttatta tcagctttat tatgccttat cgctaactgg
    53701 cgactcttta aaagagcagg ttacaaagga tggtatagtc tcattccttt ctatgcaggt
    53761 tttgtcaaac acaaaatcac ttttggagaa gataataaat ggttttactt tattggttgg
    53821 gtcattgcta tttattatta ctatgtgcac ttttgctatg tccgtgcttt tggtggatca
    53881 aagggtctag cagtatttgg cttgtttttc ccaggcattg cttctttgat agtggctttt
    53941 ggaaaaactt ataccacaca agaatgccac cctgtgccac atcttttaaa ctaagagaaa
    54001 aaagaccatc aattggattt attgatggtc ttttaggtgt ttaaatgatt ttagtcccgt
    54061 gaacaatggc cgttccagtg agtttactca agctttggca attctcagca gtgacgcctc
    54121 ctccaatcat gatttcaatg cgtttattgg cataggtcac aagactttta agctgttcca
    54181 cattgtctgt aataggagta gcttcaggtg agccatgagt tagcacacgc acaaagccat
    54241 aatcaatcag ttggtcaagc gcttggtgct ggtggtcagt cggaatatgg tcaaaagcca
    54301 tgtggaaaac cagtggcaag ccttgtgtag caggcagtaa ttgctcgata gcgtcggtat
    54361 ccagttgatt ttctgaggtc agcaagccta agactagcgc atctgagcca gcttcaacag
    54421 cttttaagat atcttcttcc atagctttta gttcgaggtc gttatagaca aaatcgccac
    54481 cgcgaggtcg aatcatggtc gctacgctaa tctttttatc gtgtaagagc tgacaggctt
    54541 ctttgatgac gccataagat ggtgttgttc ccccgacagc taggttatca cagagttcca
    54601 cacgactgac ttgaccagca tcaagggttg gcagtagtgt gaggttctca gcacaaaatt
    54661 ctttaatcat ttttaggtct cctttatcac taatattata gcacgaatga agctagtcat
    54721 caggaaacat ttttgtcaaa tcatggacat tatgctatac tcactagtat taaaagtagg
    54781 ccaaaacagc agcaaatact ttgaaaaaag attgctatgt tctacggcag tatcagtctt
    54841 taccaacgaa ctctcaagaa gaaaagaaag acaaagctta gcattttaaa aaagcccccc
    54901 ttttttttgt gaaatgatga ccaaaaacag gcgcctcgcg cctaaaacag ttaccctaaa
    54961 ggagaaaaaa tgattaccat ctaccaatac ccaaaatgta gcacctgcca aagagccatg
    55021 gctgaattaa agcaactggt tagtgacttt gaagtcattg acatcaaagc taatccaccc
    55081 aaagctcagg acctcaaaca ttggatggaa acatctggtc ataccatcaa aaatttcttt
    55141 aataccagtg gtaacagcta ccgcgaattg ggacttaaag ataaaataga ccagcttagc
    55201 cttgataaag ctgctgaact cttagccaca gatggtatgc tgattaaacg gcctattctg
    55261 attaaggatg gtaacgtctt acaagttggc tatcgcaagc catatcaaga gttggattta
    55321 ggataatgcg acaaagtttc aaaaaaggac aaggcaacat tataacgcct tgtccttttt
    55381 tgggatctgt ttttagaaat tagagatcaa tatctagtaa aattggcgta tggtcttggc
    55441 gttccccaga agaaatcatt tcagaacgct taaccttatc cacaagtcgg tttgaagcta
    55501 gccaatagtc aattctccaa ccggtattat tgattttgct ggttttgcta cgttgtgccc
    55561 accaggtata aacatgagga atatcgccgt gcaagtgacg aaaagtatct gtaaagcctc
    55621 ttgctaatag gttagtaaag ccttgacgtt cttcgtcggt aaaaccagga gaacgtcgat
    55681 tgctgcttgg atttgccaaa tcaatctctt tatgggcaac gttgtaatct cccgtagcca
    55741 aaacaggctt ttgagcatcc agttcagtca agtaatcagc gtatttgtgg tcccaaattt
    55801 gacggtcatc taaccgtcta aggccatcac cagcattagg cgtgtaaacc tgtgtgacga
    55861 aaaagtcttc aaattctagg gtaatgatac ggccctcagc atccattgtt gttggggcac
    55921 caatttctgg aaaagtaatg acagggttta acgtgttttt gtacaggaac atggtgccag
    55981 catagccttt cctagcaggc tcaactgaag aacgccacac atgcaaatag tttggaaagt
    56041 aactaagtag agtctcaata tgttttttgg taggcccctt agcagataat ttggtttctt
    56101 gaatggcaat aatatccgca tcttgagcga ctaaagtgtc taaaacagcg cgtgataaaa
    56161 gcgcacgagg ggactctcct gtgagagcag catttaagga atcaatgttc catgaaatca
    56221 gtttcatttg gtttctcttt ctaacagata gtcttgttgt tattgtaaca aaaaacgaaa
    56281 cgataagcga ctttgggcac ctagccccca taaaacagtc tagccaaatg aagcatagca
    56341 gcgtaagaac aagacaagga ggtgatcagt gagcatatcg tttgacagtt aagagtagga
    56401 ttactataat agaaacttaa atgtaagcgc taacaaaata aaaaaatata ggagaatgtc
    56461 aatggcacaa aaaacagtca tcaccgaaga aacaaccgat tttgttatgg atttcaaaac
    56521 aagtagcgct gagggaaatg ttgattttat taacgttttt gaccttgaga aaatggcaca
    56581 acaggtcatc cctaaaggag cctttggtta tattgctagt ggtgctggtg atacctttac
    56641 cctccatgaa aatattcgct catttaatca taaattaatt gtccctcact ccctcaaagg
    56701 ggttgaaaat ccgtcaacag agattacgtt tgatggtgat cacttaacct ctcctcttat
    56761 tttagcacct gtaacggctc ataagctggc caatgaacaa ggagaagtag cgtctgccaa
    56821 aggattgaag gaatttggaa gtatctacac cactagttcc tactcaacaa ctgacctgcc
    56881 agaaatcagt gctgccttag gtggaacacc ccatattaca gtaaagacga tggcattaat
    56941 cgtaatatta tggatcgtgt caaagcacaa ggttgcaaag ctatcgtttt gacagcagat
    57001 gcaacagttg gaggaaaccg cgaagttgat aggcgaaacg gttttgtttt tccggtcggt
    57061 atgccaattg ttcaagaata tttacctgat ggtgcaggta aaacaatgga ttatgtctat
    57121 aaatcagcta aacaagcgct tacctcaaaa gatattgaat atatcgcaac ttactcaggc
    57181 ctgcctgttt atgtcaaagg accacagtgt gctgaggata ccttgcgggc attggacgca
    57241 ggagcatcag gtatctgggt aaccaatcat ggtggccgtc aactagatgg tggtccagct
    57301 gcttttgatt ccttacaaga agtcgctgaa gcagttgatc acaaagttcc tattgtcttt
    57361 gactcaggta taagacgggg tcaacatatt ttcaaagctc ttgcttcagg tgctgacctt
    57421 gttgccttgg ggcgtccagc gatttacggc ttggctatgg gaggaagcac tggtactcgt
    57481 caggtctttg aaaagttaaa tgacgagtta aaaatggtta tgcaactggc tgggacacag
    57541 actatccaag atgttaaagc ctttaacctt cgccataatc cgtatgattc atcgattcca
    57601 tttgatcaaa atgcgctacg cttagattag aacagacaaa aacctctgct atcatgtcac
    57661 aaatagtaga ggttttacac tgcaaaaaga ggcatgaaaa tccaataaca tagttacaag
    57721 gctttcgttt aacacccccc attaatagat taaaatgaaa gacttcttac attaatagaa
    57781 gtttctgttg cttttctcag aaaaatgtgg ttaaataatc aaatattatt aacgaaaaat
    57841 gagttaatga ttaacattaa actggtttta gttaaaacat ttaggagggt atcaggtgga
    57901 gaaaaagcaa cgtttttccc ttagaaaata caaatcagga acgttttcgg tattaatagg
    57961 aagcgttttc ttgatgatga tgacaacaac agtagcagca gatgagctaa ctacaacgag
    58021 tgaaccaaca atcacgaatc acgctcaaca acaagcgcaa catctcacca atacagagtt
    58081 gagctcagct gaatcacaat ccccagacac atcacaagta actccagaga caaatcgtga
    58141 aaaagagcaa ccacaaggtc tagtctctga gccaacaaca actgagctag ctgacacaga
    58201 tgcagcacca atggctaata caggtcctga tgcgactcaa aaaagcgctt ctttaccgcc
    58261 agtcaataca gatgttcacg attgggtaaa aaccaaagga gcttgggaca agggatacaa
    58321 aggacaaggc aaggttgtcg cagttattga cacagggatc gatccggccc atcaaagcat
    58381 gcgcatcagt gatgtatcaa ctgctaaagt aaaatcaaaa gaagacatgc tagcacgcca
    58441 aaaagccgcc ggtattaatt atgggagttg gataaatgat aaagttgttt ttgcacataa
    58501 ttatgtggaa aatagcgata atatcaaaga aaatcaattc gaggattttg atgaggactg
    58561 ggaaaacttt gagtttgatg cagaggcaga gccaaaagcc atcaaaaaac acaagatcta
    58621 tcgtccccaa tcaacccagg caccgaaaga aactgttatc aaaacagaag aaacagatgg
    58681 ttcacatgat attgactgga cacaaacaga cgatgacacc aaatacgagt cacacggtat
    58741 gcatgtgaca ggtattgtag ccggtaatag caaagaagcc gctgctactg gagaacgctt
    58801 tttaggaatt gcaccagagg cccaagtcat gttcatgcgt gtttttgcca acgacgtcat
    58861 gggatcagct gaatcactct ttatcaaagc tatcgaagat gccgtggctt taggagcaga
    58921 tgtgatcaac ctgagtcttg gaaccgctaa tggggcacag cttagtggca gcaagcctct
    58981 aatggaagca attgaaaaag ctaaaaaagc cggtgtatca gttgttgtag cagcaggaaa
    59041 tgagcgcgtc tatggatctg accatgatga tccattggca acaaatccag actatggttt
    59101 ggtcggttct ccctcaacag gtcgaacacc aacatcagtg gcagctataa acagtaagtg
    59161 gatgattcaa cgtctaatga cggtcaaaga attagaaaac cgtgccgatt taaaccatgg
    59221 taaagccatc tattcagagt ctgtcgactt taaaaacata aaagatagcc taggttatga
    59281 taaatcgcat caatttgctt atgtcaaaga gtcaactgat gcgggttata aagcacaaga
    59341 cgttaaaggt aaaattgctt taattgaacg tgatcccaat aaaacctatg acgaaatgat
    59401 tgctttggct aagaaacatg gagccctggg agtacttatt tttaataaca agcctggtca
    59461 atcaaaccgc tcaatgcgcc taacagctaa tgggatgggg ataccatctg ctttcatatc
    59521 gtacgaattt ggtaaggcca tgtcccaatt aaataccaat ggtacaggaa gtttagtgtt
    59581 tgacagtgtg gtctcaaaag caccgagtca aaaaggcaat gaaatgaatc atttttcaaa
    59641 ttggggccta acttctgatg gctatttaaa acctgacatt actgcaccag gtggcgatat
    59701 ttactctacc tataacgata accactatgg tagccaaaca ggaacaagta tggcctctcc
    59761 tcagattgct ggcgccagcc ttttggtcaa acaataccta gaaaagactc agccaaactt
    59821 gccaaaagaa aaaattgctg atatcgttaa aaacctattg atgagcaatg ctcaaattca
    59881 tgttaatcca gagacaaaaa cgaccacctc accgcgtcag caaggggcag gattacttaa
    59941 tattgacgga gctgtcacta gcggccttta tgtgacagga aaagacaact atggcagtat
    60001 atcattaggc aacatcacag atacgatgac gtttgatgtg actgttcaca acctaagcaa
    60061 taaagccaaa acattacgtt atgacacaga attgctaaca gatcatgtag acccacaaaa
    60121 gggccgcttc actttgactt ctcgctcctt aaaaacgtac caaggaggag aagttacagt
    60181 cccagccaat ggaaaagtga ctgtaagggt taccatggat gtctcacagt tcacaaaaga
    60241 gctaacagaa cagatgccaa atggttacta tctagaaggt tttgtccgct ttagagatag
    60301 tcaagatgac caactaaata gagtaaacat tccttttgtt ggttttaaag gacaatttga
    60361 aaacttagca gttgcagaag agtccattta caggttaaaa tctcaaggca aaactggttt
    60421 ttattttgat gagtcaggtc caaaagacga tatctatgtc ggtaaacact ttacaggact
    60481 tgtcactctt ggttcagaga ccaatgtgtc aaccaaaacg atttctgaca atggtctaca
    60541 cacacttggc acctttaaaa atgcagatgg caaatttatc ttagaaaaaa atgcccaagg
    60601 aaaccctgtc ttagccattt ctccaaatgg tgacaacaac caagattttg cagccttcaa
    60661 aggtgttttc ttgagaaaat atcaaggctt aaaagcaagt gtctaccatg ctagtgacaa
    60721 ggaacacaaa aatccactgt gggtcagccc agaaagcttt aaaggagata aaaactttaa
    60781 tagtgacatt agatttgcaa aatcaacgac tctgttaggc acagcgtttt ctggaaaatc
    60841 gttaacagga gctgaattac cagatgggca ttatcattat gtggtgtctt attacccaga
    60901 tgtggtcggt gccaaacgtc aagaaatgac atttgacatg attttagacc gacaaaaacc
    60961 ggtactatca caagcaacat ttgatcctga aacaaaccga ttcaaaccag aacccctaaa
    61021 agaccgtgga ttagctggtg ttcgcaaaga cagtgtcttt tatctagaaa gaaaagacaa
    61081 caagccttat acagttacga taaacgatag ctacaaatat gtctcagtag aagacaataa
    61141 aacatttgtg gagcgacaag ctgatggcag ttttatcttg ccgcttgata aagcaaaatt
    61201 aggggatttc tattacatgg tcgaggattt tgcagggaac gtggccatcg ctaagttagg
    61261 agatcaccta ccacaaacat taggtaaaac accaattaaa cttaagctta cagacggtaa
    61321 ttatcagacc aaagaaacgc ttaaagataa tcttgaaatg acacagtctg acacaggtct
    61381 agtcacaaat caagcccagc tagcagtggt gcaccgcaat cagccgcaaa gccagctaac
    61441 aaagatgaat caggatttct ttatctcacc aaacgaagat gggaataaag acttcgtggc
    61501 ctttaaaggc ttgaaaaata acgtgtataa tgacttaacg gttaacgtat acgctaaaga
    61561 tgaccaccaa aaacaaaccc ctatctggtc tagtcaagca ggcgctagtg catccgctgt
    61621 tgaaagtaca gcctggtatg gcataacagc ccgaggaagc aaggtgatgc caggtgatta
    61681 tcagtatgtt gtgacctatc gtgacgaaca tggtaaagaa catcaaaagc agtacaccat
    61741 atctgtgaat gacaaaaaac caatgatcac tcagggacgt tttgatacca ttaatggcgt
    61801 tgaccacttt actcctgaca agacaaaagc ccttggctca tcaggcattg tccgcgaaga
    61861 agtcttttac ttggccaaga aaaatggccg taaatttgat gtgacagaag gtaaagatgg
    61921 tatcacagtt agtgacaata aggtgtatat ccctaaaaat ccagatggtt cttacaccat
    61981 ttcaaaaaga gatggtgtca cactgtcaga ttattactac cttgtcgaag atagagctgg
    62041 taatgtgtct tttgctacct tgcgtgacct aaaagcggtc ggaaaagaca aagcagtagt
    62101 caactttgga ttagacttac cggtccctga agacaaacaa atagtgaact ttacctacct
    62161 tgtgcgggat gcagatggta aaccgattga aaacctagag tattataata actcaggtaa
    62221 cagtcttatc ttgccatacg gcaaatacac ggtcgaattg ttgacctatg ataccaatgc
    62281 agcaaaacta gagtcagata aaatcgtttc ctttaccttg tcagctgata acaacttcca
    62341 acaagttacc tttaagatga cgatgttagc aacttctcaa ataactgccc actttgatca
    62401 tcttttgcca gaaggcagtc gcgttagcct taaaacagct caaggtcagc taatcccgct
    62461 tgaacagtcc ttgtatgtgc ctaaagccta tggcaaaacc gttcaagaag gcacttacga
    62521 agttgttgtc agcctgccta aaggctaccg tatcgaaggc aacacaaagg taaataccct
    62581 accaaatgaa gtgcacgaac tatcattacg ccttgtcaaa gtaggagacg cctcagattc
    62641 aactggtgat cataaggtta tgtcaaaaaa taattcacag gctttgacag cctctgccac
    62701 accaaccaag acaacgacct cagcaacagc aaaagcccta ccatcaacgg gtgaaaaaat
    62761 gggtctcaag ttgcgcatag taggtcttgt gttactcgga cttacttgcg tctttagccg
    62821 aaaaaaatca accaaagatt gataacaaaa cgcacagaga caacaaatca tcccttttaa
    62881 cagtcggacc tttctttgag attgagctgg cagatgatca tttcttaaca aaagttaaag
    62941 agttgagcaa agtaaggaac agacaataac accataaaag caagccagtt tggcttgctt
    63001 ttatggtgtt attgtcgtgt gctacgatga ctaaaaaaga acaacgaaca atgacctcga
    63061 atcaccaaaa ggacttgatt tgatagcttc cctatgctat actaagccta ttctttcaag
    63121 aaggattcct tttgtggaaa agactgaaaa aaaggacact aatctatcca aaaactccag
    63181 atgagtagct gcaaacgatg cctttgctgt gatcaaggtg gtaaagcaga ctggcttgtc
    63241 actacctgag caggtgtcaa aaaaaagaag cttttggctt tgtcattcaa catactgaac
    63301 ttcagtattt tagaacggag acacccccag ttttgtactc aaaaagcata aacagctctg
    63361 ctgatgtgac atctgatttc tacgtgcgca gtgagccaaa acagctgctt tttgctatgg
    63421 aaaaagtggc gccaatcgag atttttgaga ccctaggctc aaaaataagg catagaattc
    63481 caaaggaagt cgctgccgtg agcacaacct aagaaaaact atcccaaaag actttttctg
    63541 caatttgaaa tactgaattt cagtattttt tcttttgtaa ctaagagcaa tgaatgaggt
    63601 aaaaaaggca acaatgtcaa aaaagaaacg aaaacactat caggtttatg agggattacg
    63661 ctgtgctatg acgctttgtt ttatcagtgg ctatgtcaat gcctttacct atatgaccca
    63721 aggcaaacgt tttgcaggtg ttcagacagg caaccttttg tcatttgcca ttcgcttgtc
    63781 agaacagcaa ctgaaggagg cactgcaatt tttacttccc atgatagttt ttatgcttgg
    63841 gcagtccttt acttatttca tgcatcgctg ggccactaaa aaagggctcc actggtacct
    63901 cttatcaagc tttatcttaa cagggattgc ttttggaacg gccctattca cgccttttct
    63961 tccttccaat gttacggtag cagctttagc cttttttgcc tctattcagg ttgatacgtt
    64021 taaaacctta cgaggagcta gctatgctaa tgtgatgatg acaggaaata tcaaaaatgc
    64081 cgcctattta ctaaccaaag gcttgtacga aaaaaatcac gaactaacac atatcggacg
    64141 caacacctta atagtcatct tggcttttgc tgttggggtg gtttgttcga cgttgctttg
    64201 catagcttat ggcgagtatg ctttgatgcc tattttaatg cctttactct atgtcaatta
    64261 cctgttgact caggaatttt atcacattca aaccaaaatc aaaccgatta aaagaactta
    64321 acggacttgt ggagaaagaa agttcattta gggtaagttt ttacttaccc tccgttaatt
    64381 gactggtttt gctgcccctt aaaatatgat ataatagacc attgatagct gttacttaac
    64441 agaaggctga taaaaaaggt tccattagcc ttgagggttg aatttaaaca ggaaaaaacg
    64501 aaatcctaca ctatgcatct caatcgtact ttcatttgag tatggttctg aaaggaaact
    64561 atgatgaaaa aaccatttta cattacgaca cccatttatt acccatctgg gaaattacac
    64621 attggttctg cctatacaac tattgcttgt gatgtcttgg cacgctacaa gcgcctgatg
    64681 ggtcatgagg tcttttacct cacaggacta gatgagcacg gacaaaagat tcaaaccaag
    64741 gcaaaagaag ctggtattac acctcaaacc tatgttgata acatggcaaa ggatgtcaaa
    64801 gccctttggc aattgctaga tatttcctat gacacattta tccggacaac ggacgattac
    64861 cacgaagagg tcgttgctgc tgtctttgaa aaattgctgg cgcaagacga catttacctt
    64921 ggcgaatact ctggttggta ttctgtctct gatgaggaat ttttcactga aagccaatta
    64981 aaagaagtct ttagagatga agacggtcag gttattggag ggattgcccc atcaggtcat
    65041 gaggtcgagt gggtctctga agaatcctac ttcctacgcc ttagcaaata cgctgatcgt
    65101 cttgtggcct tctttaaaga gcgacctgac tttatccaac cagacggtcg tatgaatgaa
    65161 atggtgaaaa actttatcga gccaggtcta gaagatttgg ctgttagccg tactaccttt
    65221 acatggggtg tacctgttcc atcagaccca aaacacgtgg tttatgtgtg gattgatgcc
    65281 ctcttaaatt acgcgacagc tcttggttat ggtcaagcta atcacgctaa ctttgataaa
    65341 ttctggaatg gaacggtttt ccacatggtt ggaaaagata tcttacgttt tcatagcatc
    65401 tactggccaa tcttactcat gatgcttgat ttaccaatgc cagaccgctt aattgcccat
    65461 ggttggtttg tcatgaaaga cggtaaaatg tctaaatcaa aaggcaatgt ggtctatcca
    65521 gaaatgttag tggagcgctt tggacttgat cctcttcgtt attacctcat gcgttctttg
    65581 ccagtgggtt cagacgggac ctttacccct gaagattatg tgggtcgtat caactatgaa
    65641 ttggccaacg atcttggtaa tttattgaat cgtaccgttg ccatgatcaa caagtatttt
    65701 gacggcacgg tgccagctta tgttgacaat ggaactgcct ttgatgctga cttaagtcaa
    65761 ctgattgatg ctcagctagc agactaccat aagcacatgg aagctgtaga ctacccacgc
    65821 gccttggagg ctgtttggac catcatcgct cgtaccaaca aatacatcga tgaaaccgct
    65881 ccttgggtgc tcgctaaagg agatggagac aaagctcaac tagccagtgt catggcacac
    65941 ttggcagcta gcttgcgcgt ggtcgctcat gtgatccaac cctttatgat ggaaacatca
    66001 gctgctatca tggcccagct tggcttagcg cctgtttctg acttgtcaac acttgctcta
    66061 gcagattttc ctgccaatac aaaggtcgtt gccaaaggga caccgatttt cccacgtctt
    66121 gacatggaag ctgagattga ctacatcaaa gcccaaatgg gtgacagctc agctatttcc
    66181 caagaaaaag aatgggtccc tgaagaggtt gcgctcaaat ctgaaaaaga cgtcatcaca
    66241 tttgaaacct ttgatgctgt ggaaatccgt gtggcagaag tcaaggaagt gtcaaaagtg
    66301 gaaggttcag aaaaattgct gcgctttaga gtagatgcag gagacgggca agaccgtcaa
    66361 attttgtcag gtattgccaa atgctacccc aacgaacaag aattagtggg caaaaaacta
    66421 caaattgttg ctaacctgaa accgcgtaaa atgatgaaac aatacatcag ccaaggcatg
    66481 attttatcag cagagcatgg agatcagcta acggtcttaa ccgttgatcc ctctgttcca
    66541 aatggaagta tcattggctg atgctgacct attattcaaa aaacctaagc aagaacatgt
    66601 gcttaggttt ttttgattgc cttcaagaaa gacgaataac gagatgggtg atatggcatc
    66661 aaaagcataa ctatcctagg acctatccta gtaagattgc tgtgcttttg acaagtgaac
    66721 agagaggtct taaaactata tcttgtcata aaaaagattg caaaacacta tatcttgtgt
    66781 tattatggtt tttataaaag ttaagcatgc ttaactttag ccaaacaaaa gaggacacta
    66841 gagcgtgtcc cacaagacag ttgagccctt cgctttttta gtagagtagg agtgctcaag
    66901 tcaaaaagag acatcccatc aaaccattgc tgtttagcag gtctttttgt gttgctcaaa
    66961 aaaacaattc ctgtctgttt ggcgtctagt gatgacttag gcttagcgct actagacttt
    67021 tgtttgaaaa atacctcaag ccttgaagga gacaaatgac ccaacattat tatgaacgtt
    67081 cgcaatcccc aattgaatac gccctatctg aaacacaaaa acagttgcgc tccatcaatt
    67141 ggaattacct taatgatgac aaagatttgg aagtgtggaa ccgtgtcact caaaattttt
    67201 ggttgcctga aaaggttcct gtttctaatg atttaaattc ttggcgctcc ttgggtgagg
    67261 attggcaaca gctcatcaca aggacctaca ctgggttgac cttactagat acagtacaag
    67321 caacggttgg tgatgtggca caaattcagc attcacaaac cgaccacgaa caagtcatct
    67381 atacgaactt tgcctttatg gtggggattc atgcccgctc ttacgggacg attttttcga
    67441 ccctttgcag cagcgagcaa atcgaagaag cacatgaatg ggtggtctca acacagagct
    67501 tgcaagaccg tgcccgcgtc ttgattcctt actatacggg tgatgaccct ttgaaatcaa
    67561 aagtagcagc agctatgatg ccaggatttt tgctgtatgg cggcttttac cttccttttt
    67621 acctatcagc acgtggtaaa atgccaaaca catctgatat catccgcctg attttacgcg
    67681 acaaagttat tcacaactat tacagtggtt acaaatacca acaaaaagta gcacgtctta
    67741 gcccagaaaa acaggctgaa atgaaggcct ttgtctttga cttgctctat gaactcatcg
    67801 accttgaaaa agcttacttg agagaactgt atgcaggctt tgatttggca gaagatgcta
    67861 tctgctttag cctttataac gctggaaaat tccttcaaaa tttgggatat gagtcgccct
    67921 tcacagatga agaaacgcgc gtttcaccag aagtttttgc tcagctatca gcgcgtgcag
    67981 acgaaaacca tgactttttc tcaggcaatg gctcatctta tgtgatgggg atcaccgaag
    68041 aaaccacaga tgacgattgg gagttttaag aaatggcaga gctgattatt gtgtattttt
    68101 catctaagtc caataacacc catcgcttcg tccaaaaatt aggcctgcct gctcagcgca
    68161 taccagtaga taataggcca cttgaagttt caacccatta ccttttgatt gtgcctacct
    68221 atgcagctgg tggctcagat gccaaaggag ccgttcctaa acaagtgatt cgttttttga
    68281 ataatcctaa caatcgtaaa cattgtaagg gagtgatttc ttctggaaat accaattttg
    68341 gcgatacctt tgccttagca ggccctatca tttctcaaaa attacaggtg cctcttttac
    68401 accaatttga gctattaggc actgctacag atgtcaaaaa ggtacaggcg atctttgccc
    68461 gcttaaagca tcacacacac gacaagcaaa aacaaaccaa caacctgatt acagaaagga
    68521 cacacccatg tcacaaacca atgcgtcata cctctcatta aatgcactga ctcgttttaa
    68581 aaaaccagac ggcagctacc attttgatag cgataaagaa gctgttaggc gctacctgga
    68641 agaacatgtc tcacccaatc aaatggcttt taactcacta gaagataagc tagcttacct
    68701 catcaatgaa gggtattatg agcaggccat ttttgatgcc tatcctaatg accttatcaa
    68761 ggaggccttt cattatgcct atcaacaagg ctatcgcttt ttaaatctca tgggcgctat
    68821 gaaattttac cagtcctatg ccttaaaaac cttggacggt aagcagtatc tagaaacatt
    68881 tgaagaccgt gctgtgatga atgcactctt tttagctgat ggagatcaaa cctttgtctt
    68941 tgacgtgatt gatgccatct tgcaccgacg ctttcaacca gccaccccaa cctttttaaa
    69001 tgccggaaaa caacgccgtg gcgaatacat ttcgtgctat cttcttcgtg tcgaagacaa
    69061 tatggaatct atttctcgcg ccattagcac cagcttgcaa ctctcaaaaa gaggaggcgg
    69121 agtcgccttg tgcctcacca acctcagaga aatcggagca ccgataaaag ggattgaaaa
    69181 tcaggcaaca ggcatcgttc ctgtcatgaa actactagag gactcttttt cctatgccaa
    69241 tcaactaggt cagcgccaag gagcaggtgc ggtttacctt catgcccatc atcctgaggt
    69301 actgaccttt ttagacacca aacgtgaaaa tgccgatgag aaaattcgca ttaagtccct
    69361 agcattggga cttgtgatcc cagatattac cttccagtta gccaaagaaa acaaagacat
    69421 ggcactcttt tcaccctatg atatcaagcg tgcctatggc aaggacatgt cagacatctc
    69481 catcacagag gaatacgata aactgctagc caatccagcc atcaaaaaga cctacatcag
    69541 tgctagaaag ttctttcagt taattgcaga gctacatttt gagtcaggct acccttacct
    69601 cttgtttgat gacacggtca ataagcgcaa ccctcatgcc aaaaaaggta gaatcgtcat
    69661 gtctaacctg tgttctgaaa tcgctcaagt cagcacccca agcactttca aagaagattt
    69721 gagttttgaa accattggag aggatatctg ctgtaattta gggtctatca atattgccca
    69781 ggctatggca gatgcgccac actttgaaca gctcatcaca acgagcatca gagcacttga
    69841 tcgtgtctct agagtgtctg acctgaattg tgcgccttct gttgaggcag gcaatgcagc
    69901 caaccatgca gtaggattag gcgccatgaa cctacatggg tttttggcaa ccaaccacat
    69961 ctactatgat acaaaagaag ccgttgactt tacagatctg tttttccatg ccatggccta
    70021 ttatgctttt aaagcctctt gccaattagc caaagaaaaa ggcgctttcg caggattttc
    70081 gttatcaacc tatgcagatg gcacttattt tgccaagtat ttacaagaag aagccaagcc
    70141 acaaacagcc aaggttgcca cattgttgca agattacggc ttcacattgc caacggtggc
    70201 ggactggcaa gccctagtag cagatatcaa gcagtttggc ctagccaatg cgcacttgct
    70261 agcggttgct ccgacaggct ccatcagcta cttatcatca tgcactccga gtctacaacc
    70321 agtcgttgct cctgttgagg tccgaaaaga aggtagcctg ggcaggattt acgtccctgc
    70381 ctatcagatt gaccaggcta actatgctta ctatgaacgt ggtgcctatg aggtcggccc
    70441 aaaagccatc atcgacgttg tagctgctgc ccaaaagcac gttgaccaag ccatctcatt
    70501 gaccctgttt atgaccgatc aagcgaccac acgtgacctg aaccgctcct atatccaagc
    70561 ttttaagcaa aactgtgcat cgatctatta tgtgcgagtg aggcaagacg tcctagcagg
    70621 cagcgaacag tatgacgagg atagtcttgt gacagctcct ggagctagtg atgagaccac
    70681 cacagagtgt caaagctgta tgatctaaca gctactagaa agctctcgtg tcccctatca
    70741 catgcatagg atcagtgcgc tcgaccattc aagacaagca agcatcagct cttgcttgtc
    70801 tttttttgag catcagaacg tcaaaaaaaa ggacatggag tccttttttg gtgatcggtg
    70861 ttgaggccgt cacaaactgc ctttgaagca cgcttctatg tggagctttt tgtggtcctg
    70921 tgacacgtaa gctccaacga cctccagctg acagcctctt gggaacaaga gctcaacctc
    70981 tgaaggcaca gccgaataag gctcgacaaa ggctgctttg gccccttttt tgacacagat
    71041 gcgcacctcc accggtcgat gggtcatggc gccgtttttc aaggctgtcg tgctcataaa
    71101 actgtgctta gtgtagcgtg tgccaagctt gatcttacaa aggatatgag ggtcaaactg
    71161 atggttacgg tagtaagacg tgagatcagc gtgtgaaaca ccgatatcac gcaaaaacgt
    71221 ctcgtacaca tagcggtata ccacaatgtt ccacgggatg actagccggt gagtcgcagc
    71281 atcgagctgg gccacctgat cccttagctc aggcgtgagt tggctgagct cacccttggc
    71341 cttgtctagg ctggtattga taagggctgc ctgctggcag gtataagcag ccatcgcctc
    71401 ttgctcagcc cttgggtaga cgagcccctt gccccatcgc tttttaatca gtgtctcagc
    71461 gcccttttga tccgaaaaag taaaataggc aggcgtcccc tcacaaaccg cccgctcata
    71521 gtgctcacag acaaaaagct cgaccaagcc ctcagtttgc cagaccagac taaaacagct
    71581 aagaagaagg acaatagcca gttgatagcg cttttttagc atagttcccc ctgacaccag
    71641 cccaaaaggc tgccccttcc cctaggcctt ttggctagct catgatacca ccagtttctc
    71701 agacaggcta atctttttgt catctttttc tccctaaaca gactctctta tcatgatatt
    71761 atgctattat gagcgatttg tcaatccata gcaaccgttt tttagttaga taagtaagct
    71821 tttgacctag aggcagacaa gagtgggagt acctcccgtt aactgtggtg gctaataagg
    71881 actaacacaa aatctcaaac gctttcaaaa acagctcatg agcttaaaaa aggctgatga
    71941 acaatttttt tgagtttaag agagattgcc atgattttct aatcatttga tgtttaaaat
    72001 gataaaaaca tgaacttgaa atgaaagaac gcgagtagta aactataact acatcaaaag
    72061 taatgaaatg gagtgatttt atgaaaacaa aatcaaaacg ctttttaaac ctagcaaccc
    72121 tttgcttggc cctactagga acgactttgc taatggcacg tcccgtaaag gcggagggac
    72181 ctgaaagaga tagagtagaa gatcaagaaa gagagaatcc atatcaaaaa ggtttgagag
    72241 atggcaataa agcaggttat gagcaaggca aacaggatag acaacaaaaa caaaatgtat
    72301 ccccagatgc ttctcctacc cctccagata gagataaagt tgaagtacct gagcctggga
    72361 ataaccctta tgataaggat gatgataagc agagatacaa aaatggctgg aatattgcgt
    72421 acctctcttc ttattttaat ggctggtatt ctgctgaaag gacagattat ccagaaaaca
    72481 ctgatgatca aagtgaagag cgagaatctg atgactcatc acaggatgat ggaagacatc
    72541 aaggttcagt agactcaagt tctcaacaag aagacacgga cataatttct cctgttgttg
    72601 aaacagttct tcaagctgtc ttaggcgttt tgtctagttt cttaagttgg cttgaaaaag
    72661 ctatctaggc cccaacttct ctataatacc tttatgtata ataatttatg tattgattaa
    72721 aaggaataaa tattcagatt gaagacaaac atcgatttgg tgtttgtctt ttttagtgtt
    72781 tttagataaa aatggctgtt tccgtgctta aaccacctca tctgaacaaa ataaaaaggc
    72841 tctcccgcca tccttttgac c
//
LOCUS       DAUNLR010000004        54730 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUNLR010000004 DAUNLR010000000
VERSION     DAUNLR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54730
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.004"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            130..567
                     /locus_tag="VLL59_000260"
     CDS             130..567
                     /locus_tag="VLL59_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HER6508418.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTTEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            567..1766
                     /locus_tag="VLL59_000261"
     CDS             567..1766
                     /locus_tag="VLL59_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HER6508419.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPEAREAALKAADKLVKRYQDKGGFIQ
                     AWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFRDGSGQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKNLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            1802..2290
                     /locus_tag="VLL59_000262"
     CDS             1802..2290
                     /locus_tag="VLL59_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HER6508420.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            2309..3091
                     /locus_tag="VLL59_000263"
     CDS             2309..3091
                     /locus_tag="VLL59_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HER6508421.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFAFIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            3078..3899
                     /locus_tag="VLL59_000264"
     CDS             3078..3899
                     /locus_tag="VLL59_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HER6508422.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLIMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA"
     gene            3985..5892
                     /locus_tag="VLL59_000265"
     CDS             3985..5892
                     /locus_tag="VLL59_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HER6508423.1"
                     /translation="MFFAFARFKETVNPDFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFDALTKQEERLIL
                     ASLEKQLQFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDVTDTRDILTLAATILEKPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSLCLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGIFLIIDTIQAQGNHCLVSQFILDNHLDVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKCNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNSHKIRGKVVVIN
                     HTTNEIIRLKH"
     gene            5956..6951
                     /locus_tag="VLL59_000266"
     CDS             5956..6951
                     /locus_tag="VLL59_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HER6508424.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRISESI
                     KATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(7035..9716)
                     /locus_tag="VLL59_000267"
     CDS             complement(7035..9716)
                     /locus_tag="VLL59_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HER6508425.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTMLVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(9947..10333)
                     /locus_tag="VLL59_000268"
     CDS             complement(9947..10333)
                     /locus_tag="VLL59_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HER6508426.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            10415..11716
                     /locus_tag="VLL59_000269"
     CDS             10415..11716
                     /locus_tag="VLL59_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HER6508427.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSQGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            12172..12981
                     /gene="yidA"
                     /locus_tag="VLL59_000270"
     CDS             12172..12981
                     /gene="yidA"
                     /locus_tag="VLL59_000270"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HER6508428.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGIHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            12981..14207
                     /locus_tag="VLL59_000271"
     CDS             12981..14207
                     /locus_tag="VLL59_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HER6508429.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDLDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            14194..15429
                     /locus_tag="VLL59_000272"
     CDS             14194..15429
                     /locus_tag="VLL59_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HER6508430.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYVKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(15528..16286)
                     /locus_tag="VLL59_000273"
     CDS             complement(15528..16286)
                     /locus_tag="VLL59_000273"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HER6508431.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(16527..17723)
                     /gene="tuf"
                     /locus_tag="VLL59_000274"
     CDS             complement(16527..17723)
                     /gene="tuf"
                     /locus_tag="VLL59_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HER6508432.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            complement(18076..19380)
                     /locus_tag="VLL59_000275"
     CDS             complement(18076..19380)
                     /locus_tag="VLL59_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HER6508433.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGIFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            complement(19520..22318)
                     /gene="ppc"
                     /locus_tag="VLL59_000276"
     CDS             complement(19520..22318)
                     /gene="ppc"
                     /locus_tag="VLL59_000276"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HER6508434.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQTIIAEEVALLKEMLENITRR
                     MIGDDAFTVIKSIMVLSEKQDYIELEKVIANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINHQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLNTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            22477..24276
                     /gene="pepF"
                     /locus_tag="VLL59_000277"
     CDS             22477..24276
                     /gene="pepF"
                     /locus_tag="VLL59_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HER6508435.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRASDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIRDKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNELNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVMSTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADITTEKPLRDTIQFLSNTVDQIISYTEEMSHA"
     gene            24269..24748
                     /locus_tag="VLL59_000278"
     CDS             24269..24748
                     /locus_tag="VLL59_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HER6508436.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     TDPLFAWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(24794..25177)
                     /locus_tag="VLL59_000279"
     CDS             complement(24794..25177)
                     /locus_tag="VLL59_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HER6508437.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEVLKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     TADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(25161..25664)
                     /locus_tag="VLL59_000280"
     CDS             complement(25161..25664)
                     /locus_tag="VLL59_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HER6508438.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGYQ
                     AFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            25989..26837
                     /locus_tag="VLL59_000281"
     CDS             25989..26837
                     /locus_tag="VLL59_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HER6508439.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIS
                     IATSNPSKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      26965..27061
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            27106..27669
                     /gene="thiT"
                     /locus_tag="VLL59_000282"
     CDS             27106..27669
                     /gene="thiT"
                     /locus_tag="VLL59_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HER6508440.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMTLSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLTLMIALPIHPQLFDPKD"
     gene            27759..28238
                     /locus_tag="VLL59_000283"
     CDS             27759..28238
                     /locus_tag="VLL59_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HER6508441.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            28579..29202
                     /locus_tag="VLL59_000284"
     CDS             28579..29202
                     /locus_tag="VLL59_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HER6508442.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(29310..30212)
                     /locus_tag="VLL59_000285"
     CDS             complement(29310..30212)
                     /locus_tag="VLL59_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HER6508443.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            30386..31879
                     /gene="lysS"
                     /locus_tag="VLL59_000286"
     CDS             30386..31879
                     /gene="lysS"
                     /locus_tag="VLL59_000286"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HER6508444.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVRGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            32015..32155
                     /locus_tag="VLL59_000287"
     CDS             32015..32155
                     /locus_tag="VLL59_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508445.1"
                     /translation="MTKEYISYISATIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(32252..32464)
                     /locus_tag="VLL59_000288"
     CDS             complement(32252..32464)
                     /locus_tag="VLL59_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HER6508446.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(32675..33961)
                     /locus_tag="VLL59_000289"
     CDS             complement(32675..33961)
                     /locus_tag="VLL59_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HER6508447.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(34063..34989)
                     /locus_tag="VLL59_000290"
     CDS             complement(34063..34989)
                     /locus_tag="VLL59_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HER6508448.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            35188..35472
                     /locus_tag="VLL59_000291"
     CDS             35188..35472
                     /locus_tag="VLL59_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HER6508449.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM"
     gene            complement(35631..36059)
                     /locus_tag="VLL59_000292"
     CDS             complement(35631..36059)
                     /locus_tag="VLL59_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HER6508450.1"
                     /translation="MNKSFKNLVIGAASGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     FAEVEAKEKQDDVIIDLNEDDIIIDYTEQDEPVSDTLDKH"
     gene            complement(36052..36459)
                     /locus_tag="VLL59_000293"
     CDS             complement(36052..36459)
                     /locus_tag="VLL59_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HER6508451.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(36481..37260)
                     /locus_tag="VLL59_000294"
     CDS             complement(36481..37260)
                     /locus_tag="VLL59_000294"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HER6508452.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(37257..38189)
                     /locus_tag="VLL59_000295"
     CDS             complement(37257..38189)
                     /locus_tag="VLL59_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HER6508453.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(38550..38822)
                     /locus_tag="VLL59_000296"
     CDS             complement(38550..38822)
                     /locus_tag="VLL59_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HER6508454.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(38886..39323)
                     /locus_tag="VLL59_000297"
     CDS             complement(38886..39323)
                     /locus_tag="VLL59_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HER6508455.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            complement(39310..41442)
                     /locus_tag="VLL59_000298"
     CDS             complement(39310..41442)
                     /locus_tag="VLL59_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HER6508456.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYREKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            41676..41831
                     /locus_tag="VLL59_000299"
     CDS             41676..41831
                     /locus_tag="VLL59_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508457.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            41979..42881
                     /locus_tag="VLL59_000300"
     CDS             41979..42881
                     /locus_tag="VLL59_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HER6508458.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            42881..43696
                     /locus_tag="VLL59_000301"
     CDS             42881..43696
                     /locus_tag="VLL59_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HER6508459.1"
                     /translation="MIRFLILSGYFELTMYLQLSGKLDQYINVRYSYLAYISMVLSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFVDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(43780..45219)
                     /locus_tag="VLL59_000302"
     CDS             complement(43780..45219)
                     /locus_tag="VLL59_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HER6508460.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQFTRY
                     KKKSFDWYRQVIQTNGRYLEDNFFSIGLV"
     gene            complement(45238..47100)
                     /locus_tag="VLL59_000303"
     CDS             complement(45238..47100)
                     /locus_tag="VLL59_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HER6508461.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGTATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEILFLSEVPDETFSSKLLGEGFAILPSE
                     GEVYAPFDGEVITFFPTKHAVALKNARGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDTDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            complement(47102..47944)
                     /locus_tag="VLL59_000304"
     CDS             complement(47102..47944)
                     /locus_tag="VLL59_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HER6508462.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLIVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            48272..49639
                     /locus_tag="VLL59_000305"
     CDS             48272..49639
                     /locus_tag="VLL59_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HER6508463.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFILFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQAEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            complement(49693..51243)
                     /gene="ftsY"
                     /locus_tag="VLL59_000306"
     CDS             complement(49693..51243)
                     /gene="ftsY"
                     /locus_tag="VLL59_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HER6508464.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEAVQQEDVSSEGAGSVENGPEAASVNALVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(51243..52067)
                     /locus_tag="VLL59_000307"
     CDS             complement(51243..52067)
                     /locus_tag="VLL59_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HER6508465.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            complement(52071..52868)
                     /locus_tag="VLL59_000308"
     CDS             complement(52071..52868)
                     /locus_tag="VLL59_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HER6508466.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKVLANPYYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            53172..54298
                     /locus_tag="VLL59_000309"
     CDS             join(53172..53406,53406..54298)
                     /locus_tag="VLL59_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HER6508467.1"
                     /translation="MSTVKRYDEEFKQSLVNLYQTGKTQSELCKDYGVSASALAKWIK
                     QYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLIPKKSKCHIHAKLKVRLLAVYRLRF
                     EHATTTLCRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKV
                     ILQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFYPDKPN
                     QVWSTDFTYISIGYKKYVYLYAILHLYSRKCIAWKLNHRMDAKLACDTLELALNKRKI
                     EGTLLFHSDQGSQFKARELRKIIDDNTIMHSFSKPGYPYDNAVTEAFFKYLKHRQINR
                     KKYQNIKQVQLDCFEYIENFYNNYNPHTANLGLTPNQKEEN"
BASE COUNT        16613 a        11631 c         9884 g        16602 t
ORIGIN      
        1 tttgattctt ttttagcaca accgttcact ttttcttttt caaaaatctt tttaaaaaag
       61 tattgacaaa gaattttgaa agcgctacaa tatttttgag taaaccggta aaccaaagga
      121 gatttattta tgattgctat tatcgttatg ggacatggac attttgcgag tgggattgtc
      181 tcatccctag agttaattgc aggaccacaa gagaaggtaa ctgcaattga ttttactact
      241 gagatgaccg ccgctgatgt gcaggaccaa ttatctcgtg ctttaatccc agaagaggaa
      301 accttagttc tttgtgacct tctaggaggt acccctttta aagtcgctgc aaccttaatg
      361 gaatctcttc caaacacgac gtgtaatgtt ctttctggcc ttaacttagc catgctgatt
      421 gaagctagtt ttgcaagaca aacagcagct tcttttgacg acttagtatc aggacttata
      481 acatgttcta aagaaggcat tgttgactgg aaaactcttt ctcagcaaga agacggtacg
      541 acagacgatg agttaggagg catttaatga cacgatcttt aaaaaccatt gctcttgaac
      601 ctatcaagca gcctgaacga tttaccaaag aagactttct aagccaagaa gacattactc
      661 aggcccttga cttagccctc aaacaagttc ggcttaatat ggactatttt aaagaagact
      721 ttccaacgcc agctaccaaa gataaccaat acgccattat ggacaacacg gaatggacca
      781 atgccttttg gacaggttgc ctttggttag cttacgaata cagtggggat gatgccatta
      841 aagctctggc tcaagcaaat gacctttctt tcctagatcg agtaacaaga gacattgagc
      901 tagatcacca tgatttgggc tttctttaca ccccttcttg catggctgag tggaaacttt
      961 taaaaacacc tgaggctaga gaagctgctt tgaaagcagc cgacaaatta gtcaaacgct
     1021 atcaagacaa aggcggcttt attcaggcct ggggagaact ggggaaaaaa gaagattacc
     1081 gtttaatcat tgattgtctc ctaaacatcc aattactctt ttttgctagc caagaaactg
     1141 gagacaaccg ttaccgtgac atggcgatca atcatttcta cgcctcagcc aatcatgtca
     1201 tccgagatga cgcctctgct taccacacct tctactttga tccagaaaca ggcgatcctg
     1261 ttaaaggggt cacccgacaa ggttatagcg atgattctgc ttgggccaga gggcaagctt
     1321 ggggcattta tggtattcct ttgacctatc gtttcctaaa agaacctgaa ctcattcaac
     1381 tcttcaaggg catgacccat tatttcttga accgtcttcc taaagaccag gtatcctact
     1441 gggatttaat ttttagagat ggaagtggac agtctcgtga tagttcagca acagccattg
     1501 ctgtgtgtgg tattcatgaa atgttaaaaa ccttaccaga tcatgatcct gataaaaaaa
     1561 catatgaagc tgccatgcac agcatgctaa gagccttgat taaggattat gctaacaaaa
     1621 atctcaagcc tggtgctcct ctactgcttc acggagtcta ttcttggcac tctggaaaag
     1681 gggtggatga aggaaatatc tggggagact attactacct tgaagctctg cttcgtttct
     1741 acaaagactg gaacccttac tggtaacaaa caccgataat cacatttaaa aaggagattt
     1801 tatgacacaa ccaaacatta tcatgacgcg agttgatgag cgcttgattc acggacaggg
     1861 gcaattatgg gtcaaattcc tcaactgcaa cactgttatc gtcgctaacg atgcggtttc
     1921 tgaagataag attcaacaat ccctcatgaa aacagttatt ccatccagta ttgccattcg
     1981 ttttttctcc attcaaaaag tgattgacat cattcataaa gcaagtcctg ctcaaagtat
     2041 cttcatcgtg gtcaaagatt tgcaagatgc caaacgccta gttgaagggg gtgttcccat
     2101 cacagaaatc aatatcggta atattcataa aactgatgat aaggttgcga ttacccagtt
     2161 tatttcgctg ggagaaacag acaagtctgc tattcgttgc ttagcccatg accaccacgt
     2221 ggtttttaac accaaaacaa ctccagctgg caatagcgcc tctgacgttg acatcttaga
     2281 ttatatttaa tgaataaagg agattgatat ggatatcaat ttgttacagg cacttttaat
     2341 tggtctttgg acagcctttt gtttcagcgg aatgttactt ggcatctaca ccaaccgttg
     2401 tattattctg tcttttggtg tagggatgat cttaggtgac ttgccaactg cacttagcat
     2461 gggagctatc tccgaattag cttatatggg atttggagtg ggtgccggtg gtaccgttcc
     2521 tcctaatcct atcggccctg gtatctttgg taccttgatg gctattacca gtgctggtaa
     2581 agtcacccca gaagcggcac tagccttatc aacaccaatc gcagttgcca tccaattcct
     2641 tcaaacattc gcctatacag cttttgctgg cgctcccgaa accgctaaaa agcaattgca
     2701 aaaaggcaat attagaggct tcaaattcgc tgccaacggc actatctggg ctttcgcttt
     2761 tatcggatta ggccttggtt tattaggtgc cttgtcaatg gatactctcc ttcacttggt
     2821 tgattatatc ccacctgtct tgctcaatgg attgactgtt gctggtaaaa tgttacctgc
     2881 tatcggattt gccatgatct tatcagttat ggccaagaag gagttgattc cttttgtact
     2941 gattggttat gtttgtgcag cctacctcca aattccaacc atcggtatcg ccattattgg
     3001 tatcattttc gccttgaatg aattttacaa caaacctaaa caagtcgatg caacaactgt
     3061 ccaaggaggc caacaagatg actggatcta ataaattaac caagaaagat tacctcaaaa
     3121 cagctctgag agctttcttc ctacaaaacg ggtttaatta cagtaattac caaggtatcg
     3181 gatacgccaa tgtcatctat cctgccttga aaaaacattt tggcagtgat aaaaagggct
     3241 tatatcaagc tttagaagat aactgtgagt tttacaatac taaccctcac ttccttcctt
     3301 tcatcaccag tctgcacttg atcatgttag aaaatgatcg tcctgaagaa gaaacccgaa
     3361 acatcaaaat ggcacttatg gggcctttag ctggtatcgg tgactcctta tcacaatttt
     3421 gcttggcgcc actcttttca acgattgcag cttccttagc tagtgatggt ttagttttag
     3481 gtccaatttt cttcttccta gccatgaata ttatcctaac tgctattaaa atcggttctg
     3541 gtctctatgg ctacaaggtc ggcacaagct ttattgataa actaagcgaa caaatggcga
     3601 tagtatctcg tatggcaaat attgtcggtg ttaccgttat cgctggatta gctgctactt
     3661 ctgttaaaat aactgttccc attacttttg cggctggcaa ggtggatgcg gccaatacag
     3721 cacaaaaatt tgtgactatt caaggaatgc ttgataagat tgcccctgca cttttaccag
     3781 ctctctttac cttactcatg tattacctta ttaaaaacaa aaaatggaca acctacaaat
     3841 tggtcatttt aactgttatc attggtgtta ttggcagttg gttgggtatt ttagcttagt
     3901 tgtcactgag attctgttat gggtttagga actatttcct agtcacatta acaggtctct
     3961 tttcttttgg aaaggaaatg tcctatgttt tttgccttcg cacgctttaa agaaacagtc
     4021 aatccagact tttgcaggaa ttacctgcta gactatcagg ctgacagcta tgctgatcga
     4081 aaaaggatag ctgacctact cttaaccaat acctttttat ttgaagataa ttgggatatg
     4141 gagccctgcc acatccctta ccacttagat cccattactt ggcaagaggc tgtcacagat
     4201 gatcctgagt ggaattttat gttaaatcga cagacctatc tccaaacatt aatcctcgtc
     4261 taccttgttg aaagagatga acggtatctc ctaaaagcca aaagtttcat cctcaattgg
     4321 attgaatcag ctattccttt agaccctaag gggttagcta ctagaacctt agatactggc
     4381 atccgttgtt ttgcttgggt caaatgtttg atttacctta atctttttga cgccttaacc
     4441 aagcaagagg aaaggctcat cctagcttcc ctggaaaaac aacttcaatt tctccatgcc
     4501 aactaccttg ataaatacag cctcagcaat tggggaatct tgcaaaccac tgcgatttta
     4561 ttagctgatg cctactttgg ttctgacctt gatattgctg cagcaacagc tttcgctaga
     4621 aaagaattga cgcaacaaat cgcactacaa attctcgaag acggcagtca atttgaacaa
     4681 tcaaccatgt atcatgtgga agtactcaaa gcccttctgg aattaactgc tctagtccct
     4741 gattatcttc cacagcttag acctactttg cttgccatga gtgattatct cctcaaaatg
     4801 actggtccag atcataaaca aatccctctt ggtgatagcg atgttacaga taccagagat
     4861 attctaacgc ttgcagccac tatccttgaa aaaccacact taaaagctgc tgcttttccc
     4921 acacttgata tcgatagtct tctccttcta ggagaaaaag gtgtccacac ttttgaacag
     4981 ttacccgtcc aaaccttacc aacttttgcg catcactttg aacattccgg gcacattacc
     5041 atcaatcaag aaaattatta tctttttttc aaaaatgggc ccatcggtag ttcccatacc
     5101 catagcgacc aaaatagtct ctgtctctat tataaaggac aaccactttt ctgtgatgct
     5161 gggcgataca cttacaaaga agaaccatta cgctatgccc taaaaagcgc tagccatcat
     5221 tctaccgcct tcttagaaga acaattacct gagcagattg atagctcctg ggcttacctt
     5281 tcttacccca aatccaatta ttgtcacctt cgacaaaatg gacacgttta ctttattgaa
     5341 ggtagctacc agacgcaatt ctctgatagg aacaactacc aacatgaccg acaaattctc
     5401 atcttaccac caggaatttt tcttatcatt gatacgatac aggctcaagg caaccactgt
     5461 cttgtcagtc aatttattct tgataatcac ttagacgtaa agacagatca ccttagtgac
     5521 ctcagactaa tcagtgactg ccctttcact atcgaagaaa cgattttgtc aaaaaaatac
     5581 aaccaatacc tgactagtca caaactcatc aaacgaaaac cctttaaaga caagggttgc
     5641 accagtaccc tattagtccc tgacgatacc aaagttactc ccttaacacc acttcaaaca
     5701 ggcaaatgca acccaattga gactgccctt tcctggcatt taaaaggaaa gcagtttgac
     5761 tacagtatct gtgttctcca agaggattta attaaaggag aaaaactagt tctcctaaat
     5821 agtcataaaa tcagaggaaa ggtggttgtt atcaaccata ccacgaatga gattattcga
     5881 ttgaaacact aaatctttta cgagtcctta tgttataata tgactaacca ttactatttt
     5941 aaaggagtgt atgcaatgca gcgcaaagta accatcaaag atattgctga attagcgaaa
     6001 acttcaaaaa caacagtttc tttctactta aatggcaggt ttgacaagat gtctgaagaa
     6061 actaaaaacc gcatcagcga gagtatcaaa gctactaatt ataaaccgag cattgctgct
     6121 agaagtctca atgcaaaatc aactaaactc attggtgttg ttataggtga catcacaaac
     6181 agtttttcaa accaaattgt caaaggaatt gaaagcaaag cccaggaatt tggttaccaa
     6241 attatcatcg gaaacagcaa ctacgaccct tctcgcgaag atgaactcat tgaaaagatg
     6301 ctcaatcttg gtgttgatgg ttttattatt caaccaactt ctaactttag aaaatattca
     6361 cgtattatcg atattaaaaa aaagaaggtt gtcttttttg atagccaact ttacgaacat
     6421 cgcacaaact gggtcaaaac taataattat gatgctgttt atgataccat tcaacaatgt
     6481 atcgataaag gttatgaaca ttttatcatg atcacgggta accccaattt acttagcact
     6541 cgtattgaac gcgcttcagg cttcattgat gtgttagaag ctaatcatct tactcatcaa
     6601 gaaatgatta ttgatgaaaa tcagacttct tcagaggcaa ttgctcagtt tttgcaagga
     6661 tcactgacta aaaagagttt ggtttttgtc cccaattgtt gggctcttcc aaaagtattt
     6721 acagctatga agtctcttaa atttaatata ccagagattg gactagtagg atttgataac
     6781 attgagtgga caaaattttc ttcaccaaca ctaacaacta ttatccaacc cgcctatgaa
     6841 gaaggcgaac aggctactaa gattttaatc gatgatattg aaggtcacag tcaagaagcc
     6901 aaacaacaaa tttttgactg tcaagtcaat tggcaagaat caacttttta atgtcaggca
     6961 taccaatagt ccttatcatt gtaacgatta taaaaaaagg tttgagacaa ttgtctcaaa
     7021 ccttttagcg tctattaaat tgctttttca tcttgaccaa gtgatcgttg aacagctttc
     7081 accaattcaa caagaacaac catcaagaga cttccgataa taaccactaa ccattgtgtg
     7141 atcgtcaagt gtgtcacatg aaagaattga ttaaatccag gaacaacaac tgttgccatc
     7201 aatgctacaa aggccactgg aatagaatag ttgaacaatt tgtttttgaa taacccaaca
     7261 gtaaagatgg attggtaaac agatttcacg ttgtaggcat gtaccaactg aatcaaaccg
     7321 agggtcacat aagccatggt caaagcatct gcatggacat catggtagct tgtgtgttct
     7381 gggaacatca aggcaaaacc ataaacccca agaaccagca tggtttggaa ggcaccttgg
     7441 taaagaatgg cttccttcac cccaccatca aagaagcttg acttacgtcc acgaggtttg
     7501 tgcttcatca caccaggctc agcaggttca acaccaagag caatagctgg tagggtatca
     7561 gttaccaagt taatccaaag caagtgaact ggttgaagca catcccaacc aaacaaggtt
     7621 gcaaggaaga tggtaaagac ttctgccatg ttagcagaaa gtaaatattg aattgttttt
     7681 tgaatatttg agaagacctt acgtccttct tcaaccgcaa cgataatggt tgcaaagtta
     7741 tcatcggcaa gaaccatgtc agaagctccc ttagaaacct ctgtacctgt aattcccata
     7801 ccaataccaa tatctgccgt tttaagagat ggtgcatcgt taaccccatc accagtcatg
     7861 gcaacaactt tgccttcatt ttgccaagcc ttaacgatac gaactttatg ctcaggagat
     7921 acacgggcat acacagagta ttgtttaaag actttttgga actcttcatc tgataattcg
     7981 ttgagttcag cacctgtaaa gacatgatca acgccatctt cttcgataat accaagacgt
     8041 ttggcaatag cttttgctgt atcttggtgg tcaccagtaa tcatgattgg acgaatgcca
     8101 gcttccttag ctactttaac agcctgtgct gcttcaggac gttcagggtc aatcatacct
     8161 accaaaccag agaagacaag attagcctca acaatttctg tttccagtgt tggaagagca
     8221 tcagaatatt tgtaagccat catcaagaca cgaagagctt gtttggcaag actcttattg
     8281 gtatcaagaa tggttttttt atcagcatcc gtaataggac gaatttgtcc attttcttca
     8341 atctgtgtga cacgtttcaa taactgatct ggtgcacctt taacagcgat gaaatatttg
     8401 ccatcagctt gtttatgaat ggttgacatc aacttacggt cagaatcaaa tggtaattct
     8461 gccacacgag gttctgccac catagcctca cgtacgtcaa aattgtggtc taacccaaac
     8521 tgtaccaaag ctgtttctgt tgggtcacca attaacttcc ctgaaggatc aactttagta
     8581 tcattagcaa agttcattac acgaagtgtc gtattgtcaa aggcaatatc agctgatgaa
     8641 ctttgaagtg ccccgttggt ataaactttt tctacggtca tttgattcat tgtcaaggta
     8701 cccgttttat cagaagcaat gatttcagtt gatcctagcg tttcaacagc tggtaattta
     8761 cggataatgg cgttacgttt agcaagtact tgagttccaa gagaaagcac aacagtaaca
     8821 atcgcaggaa gtccctctgg aatagctgca acggcaagcg ctactgaagt catcaagcct
     8881 tcaagcgggt gttgaccacg caagaagact ccaacagcaa aagtcaccgc tgcaatcaca
     8941 aggatcgcat aagtcaaaat cttagaaagg ttgtcaaggt tttgcttcaa tggtgtatct
     9001 gtctcatcag cattagcaag cataccagca atatgcccaa cctcggtgta catgccagtg
     9061 ttagtgataa ccccaatccc acgaccatat gtcacatttg agttttgata tcccatattg
     9121 acgcgatcac caataccggc atcttctgaa acagccgttg acaagtcttt ttcaaccggt
     9181 acagattctc cagtaagcgc tgcttcttcg atttttaagg agttagcttc caaaagacgc
     9241 agatcagcag ggacaacatc tcccgcttct agcaagacaa tatctccagg gaccaattct
     9301 ttagagtcta tctcagtcac atgcccatca cggcgaatac gagccagtgg acttgacatt
     9361 gatttcaagg cttcaatagc agcttcagct tgtccttctt ggtaaacacc aaaagcagca
     9421 tttaggataa caacagccaa gataataatg gcgtctgtca aaccttccat cccctctgta
     9481 agaactgaaa gaagggctgc cacaatcaaa ataataatca tcaaatcctt aaattgatca
     9541 aggaatttca taaataaact tcgtttttcg ccttcatcaa gctcattacg accatactct
     9601 gctaagcgct cttttgcttg ggcagacgta agaccttcgc gactggtctc taattgagcc
     9661 agtacggtct cttcactttg cgtgtaaaac gcttcatgtc tttgttcttt agacaaatta
     9721 gtacctcctt ggtcttttta ttttagttat tcaaataaaa agacctgttt atttttctta
     9781 aacaagtctc gctgtttaag attgtaccgg aaaccgaaat tccgtattga cgatacaatc
     9841 acggctagcc gtctgctact cccttgatat aataacaatt atagtaaaaa cctgactaaa
     9901 aaacaagaat aatccctaat cagatgattt actgctatct ttttagttaa tcccaactca
     9961 gctcaagatg atagcttgca aatagcattt ctgtttgagc ttgaagcaaa tgataatgaa
    10021 ggtccaattt ttgacaagaa caatctaagt ggtaatgact ggtatctgtc aaaaattgtt
    10081 gaacccccat cggtgtaggt agagcaatca ggaccttctt gcccgcaaaa aatttcatga
    10141 ttgactgagg gttggaaaaa cggctcatgg tcagttctgt ctcattatac ttgatgacaa
    10201 ccttttcctt gtcagtgttt tgatagatga ggtactgata gccccctttt tctcgccact
    10261 cacaatcatg aatttcttga ataatctctg tctcatctcc aaagcgaata tggttggtta
    10321 actgtaattt cataactctt ctttctattc taagctcgtc tgtttattct atcaatttct
    10381 ccttatttta tcaatttttg atataataaa aattatgaat gaaaaagtat ttcgtgaccc
    10441 tgttcacaac tatatccaca ttgataatcc attaatttat gaccttatca ataccaaaga
    10501 attccaacgc ttacgacgca tcaaacaagt ccctacaaca gctttcacct tccacggcgc
    10561 agaacatagc cgtttttctc actgcctagg tgtttacgaa attgcccgtc gggtgacagc
    10621 tatttttgaa gagaaatacg ctgatatctg gaataaagat gaaagtctgg tcactatgac
    10681 ggctgccctc ttacatgaca ttggtcatgg agcctattct catacctttg aggccctttt
    10741 ccatacggat cacgaggcct ttactcagga gataattacc aatcctgaga cagaaatcaa
    10801 tgccattttg gtgcgtcatg ctcctgattt tccagacaaa gttgccagcg tgattaatca
    10861 tacttatcct aacaagcaag ttgtgcaact gatttccagc cagattgact gcgaccgtat
    10921 ggattacctt ttaagagatt cttatttttc tgctgccaat tacggtcagt ttgatttaat
    10981 gcgcatccta cgtgtgattc gacctgttga agatggcatt gtctttgaac atagtggtat
    11041 gcatgctgtc gaggactata ttgtcagtcg ttttcaaatg tacatgcagg tctattttca
    11101 tcccgccagc cgtgctgttg agctcatctt acaaaatctc ctcaaaagag cccaacactt
    11161 atatcctgag caacaggctt atttccaaaa aacagctcct ggactcatcc ccttctttga
    11221 aaagaaggct aatttagcag attatatagc cctagatgac ggagtcatga atacttactt
    11281 ccaagtctgg atggcaagcg aagaccatat cttatcagat ttggccagtc gctttattaa
    11341 tcgaaaaatt ctgaagtctg ttacctttga ccaagattcc caaggagagt tagaacgctt
    11401 gcgccaattg gtcgaatcag ttggctttga tccagattat tacaccggta tccatatcaa
    11461 cttcgacctg ccttatgata tttatcgacc agaactcgaa aatccaagaa ctcagattga
    11521 aatgatacaa aaagacggga gccttgctga attatctcag ttatctccta ttgtcaaagc
    11581 attaacaggg acaacctacg gagaccgtcg cttttatttt ccaaaggaaa tgttagagct
    11641 cgatgacctc tttgctccta gcaaggaaac ttttatgagt tatatttcca atgggcattt
    11701 tcactttagt cagtaaagcc ctttaagatt gcagaaaaag tcttttttga tacttttctt
    11761 aggtgatgct tatggcagcg acttcctttg gaattctatg ctttattttt gagcctaggg
    11821 tctcaaaaac cccgcgtaac gtcactgcca gtattgacac cacttttgcc acagcaaaaa
    11881 gcagctgttt tggctcacgt cacacgcaga aataagaaat cagttgtcaa atcagcagag
    11941 cagttcatgc tttttgagca tcaaactggg tttgtctcca ttctaagatt gaagaaagag
    12001 tactttcttc aatcttttta gttactacag aggcgattga gctaaactaa aacgttttct
    12061 ctcgtttttc cttaagtttc ctttcccatc ccatgacaaa agcacctatt tttagtaaga
    12121 taggagggag aacattttta agataaacca caaaaaaaca aggaggatgc catgtctatc
    12181 aaactggttg ctgtcgatat tgatggcaca ttactcactg atgaccgtcg aattacagat
    12241 gatgtttttc aagctgtcca agaggctaaa gcccaagggg ttcatgtggt gattgctact
    12301 ggcagaccta ttgccggagt gatttcatta ctcgaacaat tagaactcaa ccacaaagga
    12361 aaccacgtta tcacttttaa tggtggcttg gtgcaagatg ccgagaccgg cgaagaaatt
    12421 gttaaagaat tgatgactta cgacgattat ctggaaacgg aatttttgag ccgaaaatta
    12481 ggaattcaca tgcatgccat taccaaagaa ggtatttata ctgccaatcg gaatattgga
    12541 aaatacacag ttcatgaatc gactttggta aacatgccta ttttctatcg cactcccgaa
    12601 gaaatgacca ataaagaaat catcaaaatg atgatgattg atgaacctga ccttttggac
    12661 gcggccatca agcaaattcc tcaacatttc tttgataagt acaccatcgt caagtcaacc
    12721 cctttttatt tagagttcat gccaaaaacc gtcagcaagg gtaatgccat caaacactta
    12781 gctaaaaaac tcgggctaga tatgtcacaa accatggcca tcggggatgc tgaaaatgat
    12841 cgtgctatgt tagaagtcgt tgccaaccct gttgtcatgg aaaatggggt tcctgaattg
    12901 aaaaaaatag ccaaatacat caccaaatcc aacaatgaca gtggtgtggc acatgctatt
    12961 cgcaagtggg tattaaacta atgtatacat ataaaatcgg aatatctcct gaagaacatg
    13021 atcagtttgt cttagcacag ccacaagctg gcttacttca aagttcaaag tggggaaaag
    13081 tcaaagataa ctggaaacac gaacgcatca gcttttatga aaatggggta caagttgctg
    13141 ctgctgcttg tttaatcaga aaacttcctc ttggtttcac tatgatttat atcccacgtg
    13201 ggccaatcat ggactacgcc aattttgaac tccttgattt cgttattaaa acgctcaaaa
    13261 ctttcggaaa aagcaaacga gcgctttttg tcaaaattga tccaagttta gtcatcaaac
    13321 aaactttaga aggaaaagag agcaaagaaa atgatgtgac actctctatt attgcttttc
    13381 taaaaaagct tggtgtcgaa tggtctggca gaacaaaaga actcgaagac actattcaac
    13441 caagaataca agccaacatc tacgccaagg attttgacct tgacagcctg cccaaaaaag
    13501 ccaagcaatc cattcgtacc gctaccaata aaggtgttaa tgtcacgatt ggtggcagtg
    13561 aattgctaga cgacttttca gccttgatga aaaaaaccga gaatcgaaaa ggcattatcc
    13621 ttcgaggtaa atcctactat caaaaattac tagatattta tgctggtcag tcctacatta
    13681 ctatggctag tttagactta cctgaacaaa aaaaactctt gatccaacag ttggacaagg
    13741 ccttagcaga acaagcacga ttaacagata agagtaaacc tagcaaagta gcagaaaatc
    13801 aaaaaaccat tgcacggcta caaaaagatt taaccatttt aagcgagcag ctcgctgcag
    13861 gcaaaacccg catcccacta gccgccaccc taaccttgat ttatggcgag acttctgaaa
    13921 atctttatgc gggaatggac gatgattatc gcaattatca agctcctctt ttaacctggt
    13981 atgaaacggc taaagaagct tttaaaagag gctgccgctg gcataattta ggaggtgtgg
    14041 aaaatcaaca agatggtgga ctctatcatt tcaaagctag actcaacccc accatcgaag
    14101 aatttgcagg tgaattcaac attcctgtcg gccttgtttc aagcttagcc atcttgacct
    14161 ataacttaag aaaaaaatta aggagcacaa ctaatggcac taattgaaat ttcacaagaa
    14221 caatttgacc attactgcca cagtctcgtc catcattcct ttatccaaac ctcagaaatg
    14281 gccagcttga tggctaaaag aggggcaaaa ccacaatttc ttggacttga aaaagatggt
    14341 gaactaaagg ttgctgctat ggtctttagc caaaaagtgg ctggaggttg gcgtatggaa
    14401 ctcaatgcag gccctaatac caatcatccc gaagaattag aacattttta cactcaactt
    14461 aaagactatg tcaaacaaaa agacgttatc gaactcattt taaaacctta cgacaattat
    14521 cagtcatttg atactgatgg catccctatt tctcatccaa acactgacct tattagcctt
    14581 ttaacggcgt taggatataa acatgacggt ttaaaaacag gctatcctga gggtgaacct
    14641 gtttggcatt acgttaaaaa gttagaagga attgattcct cacgtttaac ccattccttc
    14701 agcaaaaaag gaaaagcttt aataaaaaaa gctaatactt ttggtattaa attacgtcaa
    14761 ctgaaacgag atgagttaca ccatttcaaa gaaattactg aagcaacctc tgatcgtaga
    14821 gattaccttg acaaatcatt atcttactat caggactttt atgatagttt tggagactct
    14881 tgtgaattta tggttgcgac tcttaatttt gaagattacc ttaataacct taaacaaaga
    14941 caactacaac tagcaaccag catcaacaaa gttaaaggag accttggcaa aaatcctcat
    15001 tctgaaaaaa agcaaaatag attaaaagaa ctatccagcc aattcgaaac ctttcaggta
    15061 agaatttctg aagctctcca ttttcttgaa gagtacggaa ctaaagatgt gttccttgcg
    15121 ggaagtcttt ttatctatac cgaacaagag gccgtctacc tcttttcagg atcttacccc
    15181 aaatttaata aattttatag cccagctcta ttacaagagc atgctatgct caaggcaatt
    15241 cacaagggca tcaaacaata taattttctt ggtattactg gaaagtttga tggttcagac
    15301 ggtgtcttgc gctttaaaca gaatttcaat ggctttattt tgcaaaaacc agggacattt
    15361 agatgttatc catttccaat caaatatcat ttcattagat tggcaaaaaa gctattaaac
    15421 cgctattagg ctaatgcatt tacctgtaga atcaccttta ttctctcata gtaagagtta
    15481 agtcatctaa aaaagaaaag gatttaacct tttctttttt agatgactta gttaaggaaa
    15541 tcaagcaaag caaggaagct atcagcttca agtgatgcac cacctacaag ggcaccgtca
    15601 acatctggac aagccatgta atctttaacg ttttcaggtt ttacagaacc accgtattga
    15661 acgcgaactt tatcagcaac ttcttgccca aagtctgctg ctaccacgtc acgaacagct
    15721 ttacacatgt tttgagcatc atcttgagta gctgatttac cagtaccgat agcccagatt
    15781 ggctcataag ctaaaacaag tgaagctact tgctctgctg aaagacctgc aagtgctgct
    15841 gaaacttgcg cacctacaaa ctcaacggct ttaccagctt cataagtttc aagagactca
    15901 ccacaacaaa caattggagt taaaccgtta gcaaagattg ctttggcttt tttattaatg
    15961 tcttcatctg tttcatggaa gtaatcacgg cgttctgagt gaccaatcac aacatagtca
    16021 gctcccattt cagcaagcac ttttggtgat gtttcaccag tgaatgcccc tgtgttttca
    16081 aagtagcagt tttgtgcagc aactttaaga actgaatctt tagcagcttc aatagtggtt
    16141 accaaatcaa cagctggggc tgctacggca acatcaacaa ggtcagttga aggtaatttg
    16201 cttgctacag cctcaacgaa tgcttttgct tcttgagggt ttttgttcat tttccagtta
    16261 ccagcaataa ttggtttacg tgacatatca catacctctt ctttttttat ttatattttc
    16321 tattttagca caaatgaccg acgattaaaa ggaattgctt atattttagg aatattttca
    16381 caaataaaaa ccctttttct gaaagctttt cattcttatt tatcagcatt ttatggagtt
    16441 taagatagca aaaagccccc gaattggggg cttcttcaaa cttaagttgt ctgacttaaa
    16501 ttgctattct gggaacttaa ttaaaattaa gcttcgattt ctgaaacgat acctgaacca
    16561 acagtacgtc caccttcacg aattgagaaa gtagtacctt gttctacggc gattgggtgg
    16621 atcaactcaa cgttgattgt tacgttatca ccaggcataa ccatttctgt acctgctgga
    16681 agttcgattg aacctgttac gtcagttgta cggaagtaga attgtggacg gtagttgttg
    16741 aagaatggag tgtgacgccc accttcgtct ttagaaagga tatatacttc acctttaaat
    16801 ttagtgtgtg ggttgattga acctggttta gcaataactt gaccacgttc gatttcgtca
    16861 cgttgaacac cacgaagaag gatacctacg ttgtctcctg caagaccttc gtcaagttgt
    16921 ttacggaaca tttcaacacc agtaacaaca gcttttttag tttcttcttt gataccaacg
    16981 atttcgattt cgtcgttaac acgaacagta ccacggtcga tacgtcctga agcaactgta
    17041 ccacgacctg tgattgagaa tacatcttcg actggaagaa gcaatggttt gtcagtgtcg
    17101 cgttctggtt ctgggatgta tgaatcaaca gtatccatca attccatgat gatgtcttca
    17161 aatttagtgt cgccttcaag agctttaaga gctgaacctt ggataactgg aaggtcatca
    17221 cctgggaaat cgtattctga aagaaggtca cgaatttcca tctcaactaa ttcaagcaac
    17281 tcttcgtcat caacaaggtc aactttgttc atgaacacga taaggtgttt aacaccaacc
    17341 tgacgtgaaa gaaggatgtg ctcacgagtt tgtggcattg gtccatctgt tgaagcaact
    17401 acaaggatag ctccgtccat ttgagcggca ccagtgatca tgtttttaac gtagtccgcg
    17461 tgtcctggag cgtcgatgtg cgcatagtga cgagttgcag tttcgtactc aacgtgtgca
    17521 gtgttgatag tgattccgcg ttcgcgttct tctggagcag catcgataga agcgtaatct
    17581 tttggttggt taactgatga aggcaagcga cgtgccaata cagttgtgat tgcagctgtt
    17641 aaagtagttt taccatggtc aacgtgtccg attgtaccaa tgttaacgtg gggtttacta
    17701 cgatcgtatt tttcttttgc cattttagga aaagcctcca ataaaatata ttttatagat
    17761 agacggtagg ccatacagtc taactttacc ttactattgt agcaaattac aatgaaaatg
    17821 caagtatttt atgttttttg ccatttcttt attttttaaa tagaagaaaa agtctttttc
    17881 gatactctcc ttaggtggtg cttatagcag cgacttcctt tggaattcca cgccttattt
    17941 ttgccacagc aaaagcagct gtttgggctc atatcacacg caaaaataag aaatcagcag
    18001 agcagttcaa gttttttgag catcaaactg ggattgtcta tattctaaaa tctccttaaa
    18061 ggagatttta gaatattatt gaaattgctt gatatttaca actttactat tttcttttcg
    18121 agtgtccttt cgataagata attcagcttc tttaaatata tcatctcgct tttcgctagc
    18181 atcaatattt agtacaaaac ccactgcaac agataagaca agtaagctat ttccaccttg
    18241 agacaaaaaa gggaaggtaa caccagtaga tggaattaag cctgagatac caccaatatt
    18301 aacaaagact tgcatgagca tcataccgcc tactcctaaa gccatcatgg cattaaaagg
    18361 attttttgct ttaataccaa cattcataat acgtaaaatt aagaagaaaa caagtgccaa
    18421 aataaaccct gctcctatta gacctaactc ttcaatgaca actgaaaaga caaagtctgt
    18481 ctgtgcttcg ggcaaatagc cacgcttttc aatagaattt cctaaccctt ggccaaacca
    18541 cccaccatta ctcatagcat agtaagaatt ggctaattgg tgacctgaat cggtcaagtc
    18601 atgaaaagga ttaaaaaagg cactaaaacg tttagcgaca tagccaaaaa caggaatctt
    18661 agcaactctt tctaccccaa taacggcaat agtcccaaga aagaccgtgg atagaccggt
    18721 aatcatgact aggatagccg aaaaccatcg gtaaccaatg ccactgatag aaaacataat
    18781 aatggctgtc aatacaataa tggaagcatt tcccaagtca ggctgagcag caaccaaaag
    18841 taccatcaac aaagaataaa cacgccagtc ccgtaaatcg ttccattgtg ttggccacca
    18901 ttttcgacga gttagtgctt gataatcata aaggctaatg tttttttgga tcttagcaaa
    18961 ggtcaatgcc aaataccata ccataatgat ctttaaatac tcagcaggct gaaagctgac
    19021 tggtccgatc acaatccaac catgcgctcc tttgatagca gttgtaaaga agcgggcaat
    19081 aattaaaaga aaggcctctc ctaacataac cacagttaat acccttgtat tcgttaaaaa
    19141 atttaatttt aatttataga taaatgtaat agccactaga cttattatcc aaaaaattcc
    19201 ctggttaatc accgatttaa atggattagc atgtgcttga atcaagctga cacttgtggt
    19261 tgagtaaacc attattaagc ctatcaccga taaaattaaa taaggcaata atatagaata
    19321 atttaagagg tgccttttat caatcttcat agttttccct ctacttcttg agataatcat
    19381 ttagcattat aacatctttc tatatcaaac aaaagaaaaa gtcaagaatc ctcaaaaaaa
    19441 gaagttccaa gggctaacct ttaaaattct gattagtcac ttgaaaactt ctataaatac
    19501 caattagtac tcaagagcat tagcctgaat tacgtaaacc agtcgctatg ccattaatag
    19561 ttgtatggat caatttttca tcattttcgt caagttgatt attacgccaa cgtttaatca
    19621 attcaatttg aatatagttc aacacattaa aatacggcaa gcgtgacttc aagctatgct
    19681 taagggaagg attatcctcc aatagatcat catggtcttg gatagcaaga ataacatttt
    19741 ttgtcaattg ccactcatcc aaaatctcat aaaaaacatc tcgaacatcc tgactttcag
    19801 ctagttgtgc atactgaaag gcaatattca tgtttgattt agataatacc atatcaacat
    19861 ttgataacaa ggaatggaaa aaaggccacg tctgatacat gtgttggagg cgttcaaggt
    19921 taccttgtgc tcggtcaata taacgtttaa aggctgaacc taccccatac caacctggga
    19981 acatgatgcg attttgtgac catgaaaaga cccaaggaat ggcacgcaag cctgtaattt
    20041 ccgtaatcgt tttacgggct gctggtcttg acccaatgtt gagactggaa acttccttaa
    20101 tcgggcttgc ctcaaagaaa taatcataga aatggggatt gtcaaaaacc aattttcgat
    20161 aaatggtatt gctatcagca acaatgctat ccatgatttc tcgaaaacta tcaatctcat
    20221 taggatctgt tatcatttga gtcaccatac gattgataga agctgaaatc aacatttcta
    20281 aatggtaata agccacatct ttattgccgt atttgttttc aataatttcc ccttgctctg
    20341 tcagacgaat ccgatctttg atggaaccaa aaggttgtga agtaatggca tcataagaag
    20401 ggccacctcc tcgaccaact gttcctccac gaccatggaa gaaggtgatt ttcactccat
    20461 gttcctcacc aatagccgtt aattcattct gagctttata aagagtccaa cccgatgcca
    20521 agtagccacc atctttatta ctgtcagaat aacctaacat gatttcttgg taattacgat
    20581 tcgttgcaat ccaagatttg acaatgtcat ggcttaaata ggctgccatg atgtcacggg
    20641 cattatctaa atcctcaatg gtttcaaaga ggggaacaat ttgcacacga gcccgctgct
    20701 ggtcaaccaa tcccacttct ttaagcatga tggccaactc aaacatatca gagacacttt
    20761 ctgtatgtga aataatatgt tgcttaataa cctcttctcc aagcttatct ttcaattctc
    20821 gtgccgtagt atagatagcc agttcttttt ctaataggtc tgatttagca actgccgctg
    20881 aggataaggt tcttggctcc tccattaatt gttgtaagag aacatcgcat ttttcagttt
    20941 ctgaaagaga gctataatcg tcaacaatat tggctccttt taataactct gccacacaag
    21001 cttcttggac actggagtct tgcctcatgt caatgcttgc taagaagaag ccaaaaatat
    21061 caacagcttg catgacttct cgcaaatccc cctcaatcaa agcggagttg ccattatcaa
    21121 gtagcgactg ctcaatagcc tttagatcag ctttaaaatc aacaggagag tcataggcta
    21181 agatgggatt ttctaaacta gctggtgagg accaagcaga tgtgtttagt cccacactac
    21241 tactcatacg agctgctggc tgattagtta gttgaatttg tgtttgttta agacgcgatt
    21301 gaatataatg aaaagctctg cgataaggtt catttccacg gtaaatcgat tggtcctgag
    21361 acaaactggc taaacgttcc acttccgagt tgggttgtac caaggttgac gacagtgaaa
    21421 atgttcggta aagggctgct aatttgtcaa tgtagtaatt gaggataacc tcactttgaa
    21481 ccgtagctga caagcacaag gtttcagctg tgacaaaggg gttcccatca cggtccccac
    21541 caatccacat ccccatggta atgggtttgg gattgtctaa ctctagaccg tgtttttggg
    21601 ctaaattttt gtactctgtt gtcaacttgg tcacagcctg aattagggaa ccatcgtaat
    21661 actgcatgac attttttatc tcgtttttca cctgaagctt tttctcgcga ataatatctg
    21721 tctgcatgat catttcaata taacgatata gctcctgacg ccatttctca agattaatta
    21781 caccagcctt agcatcacgg tatttgcgca gaagtttatg aatgtgagtt gtcaattcca
    21841 gaatcgtttt acgttgcact tgcgtcggat gtgctgttaa aacaggaacc acattaacct
    21901 gctccaaaat gtctttacca ttatcttttc cagcaagatc cttgatggtt agggctaatt
    21961 ttcctaaata atcagtatct gtattatttt gatgattaat ttcataggct aaatcgacat
    22021 cttctgaaat attgattagc aagggtaaaa tagaaaaata cctggaaatc acttccattt
    22081 cttgatttga aatattggcg ataacttttt ctaattctat gtaatcttgt ttttcagata
    22141 acaccataat agacttgata actgtaaacg catcatctcc aatcatccgt cgtgtgatat
    22201 tttccaacat ttctttcaaa agagcaactt cttcagcaat gatagtttga ttgttactac
    22261 tctctaactt tttaagtggc aaatgaccat ctccttcttt gctagtttct tctatcatac
    22321 cactttttac caaaaataaa agtgagcatg ttcataacgt ttgtttttta acaaaagtaa
    22381 acgctttatt ttaaagaatg tttggatagg tttagtctcc atattccact aaaattctgt
    22441 tatactagtc ttgactatat tgttaaggag acaactatgg aattgaaaaa acgttcagaa
    22501 ttccctgaaa atgaactttg ggatctaaca gcgctctaca aagaccgcca agatttttta
    22561 ctcgctattg aaaaagcctt acaagatatt gacctgttta agcgcaatta tgaaggccgc
    22621 ttaacatcgg tggacgattt cactcaggcc ttaatagaaa ttgagcatat ttatattcaa
    22681 atgagtcata ttggcactta tgcctttatg cctcaaacca ctgacttttc agatgaaagt
    22741 tttgctcaaa ttgctcaggc tggcgatgat ttcatgacta aagctagcgt tgcccttagc
    22801 ttctttgaca ccgccttagc caatgccgac cttgacgtgt tagatacatt agaaaagaac
    22861 ccttatttca gcgcagctat tcgcatggca aaaattcaaa aggaacacct cttaagtcct
    22921 gatgtggaaa aagctttggc taacttacgc gaggttatca atgcgcccta tgatatttac
    22981 accaaaatgc gggctagtga ctttgacatg gatgattttg aggtagatgg taaaacctat
    23041 aaaaatagct ttgtttctta cgaaaatttc tatcaaaatc acgaaaatgc tgagattcgt
    23101 gacaaagctt ttcgttcctt ctcaaaaggt ctccgtaaac accaaaatac agctgcagcg
    23161 gcttacttag ccaaggttaa atctgaaaaa ttgttagctg atatgaaagg ctacgcttct
    23221 gtctttgatt acctcctagc tgaacaggaa gtggatcgta gcttgttcga ccgccaaatt
    23281 gacctcatca tgactgaatt tggaccggtt gctcagaaat tcttaaaaca tgtcgcccaa
    23341 gtcaatggtc ttgagaaaat gacttttgct gactggaaac tagatattga taatgagctc
    23401 aatccagagg tcagcattga tggcgcttat gacctcgtga tgaaatctct agccccatta
    23461 ggacaagaat acacgaaaga aatcgaacgt tatcagacag aacgctgggt tgactttgct
    23521 gctaatgcca ataaagattc tggtggttat gccgctgatc cttacaaggt ccatccgtat
    23581 gtcttaatga gctggactgg cagaatgtct gatgtctaca cgctcattca tgaaatcgga
    23641 cactctggcc aatttatttt ctctgataat caccaaagtt acttcaacac ccatatgtca
    23701 acttattacg tcgaagcgcc atcgaccttt aatgaattga tgcttagtga ttacttggaa
    23761 catcaatttg atgaccctcg tcaaaaacgt tttgcccttg ctcaccgttt aacagacact
    23821 tactttcata acttcatcac tcacctattg gaagcggctt tccaacgtaa ggtttacacc
    23881 ctgattgaag aaggcggtac ctttggagct gaccaattaa atgcgatgat gaaagaggtc
    23941 ttaacagact tctggggaga tgccgttgac attgacgatg acgcagctct tacctggatg
    24001 cgccaagcgc attactacat gggcttatat agttatacct attctgctgg gcttgttatg
    24061 tcaacagctg gttaccttaa ccttaaaaac aacccagatg gggcaaaaga atggcttgac
    24121 ttcctaaaat caggtggcag ccgtacgcct cttgatactg caatgctcat tggggcagac
    24181 attaccaccg aaaagcctct tcgagatacc attcaattct tgagtaatac cgttgaccaa
    24241 attatcagtt acaccgagga gatgtcacat gcctaatctc tatgatttta cggttaaggc
    24301 tcaaaacggg aatgaccttt ccttagctgc ttataaaaaa aaggttgttt tgattgttaa
    24361 cacagctacc aagtgtggat taaccccaca ataccaggcc ttgcaagcac tatatgacac
    24421 ataccatgac aagggatttg aggtcttaga ttttccttgc aaccaatttt taaatcaagc
    24481 tccaggagat gctgaggaga ttaatcactt ttgcagtctg acctatcaca ctactttccc
    24541 tcgctttgca aaaatcaaag tgaatggtaa agacactgat cctttgtttg cctggttaaa
    24601 agaagaaaaa agtggtcccc ttgggaaacg catcgaatgg aatttcacta aatttctcat
    24661 tgaccaaaat ggtcaagtca ttaaacgcta ttcctcaaag acagatccta aactaattga
    24721 agaagacctt aaagcacttc ttggttaata taaaatagac ttggcgtgcc aagtctattt
    24781 tatattatag ttactattta aaaacttctt gataaaattc aatgctatca ccatctttaa
    24841 cggtaatttg atcggcaccc ttatctgccg tctttccatt caccttaaaa agccaatatt
    24901 tgttagcttt cgtgtcttgc tcgataccat caattgctgt gataaaacca tctttttctt
    24961 tgacctcata attatctttg agaacctcaa gcaccgtatc tccttttcca aaagaaactt
    25021 tttcatcaat ggtattggta tcttctttga caactaagcg aacgtgatgg tctgcttttg
    25081 gaacgcttgg agtctgtgtt tgttttgttc cttgcgagca agcaacaagt agcatagcaa
    25141 caagcgctag aaatcctgtt ttaaatcttt tgttcaccga ttaacctcct aaataacatc
    25201 atcacaactg gaaaaaagac gagagttgat aaagcatgcg ctatattaaa gggcatccca
    25261 gctagaacat agctccacca aggcatacta tacaaatacg caaaacaagt atctatcaac
    25321 accccataaa ggaggccaca taaggcggcc aagaaagcct gataaccaag ctgatatttg
    25381 gggaattgct gagacagagg gtacaagaca aaacgccata ataaaagaac aagcacaaaa
    25441 caagtaactt gccaaaagac ccaagggcca aatcccagca aaaaggctga taaaaataag
    25501 cacaacatca taactaatac agcctcggct aacccaaagt aaagaagata actgagtaaa
    25561 aatgccgtca caggctgcac gttaggcagg ctgctaaaaa ccattctcaa cacaacacat
    25621 agggctgaca tgatagcaat gcgactcata agcttagctg acataaactt cttcctcgtt
    25681 tttttctcta ttatgacaga tttacagagc gtttaccagt ttggagctca cttatttatc
    25741 aaatgataat aacatgagaa ttaaataaca aaacagtact tgctgactgt catgatatag
    25801 tcaaagacta aactaatatt gtaaagaata tagctaccaa ctataagaga tagtgacata
    25861 aacttgacat agttagagag gatctcattt gtaacttcta aaagataata ccttaaaatg
    25921 caagacaata taagaaaaca gttaggatat tttgattttt tttagtaatt agggtacaat
    25981 aacagttaat gagaagaaaa ataaaaccta ttgttgtgct agtcttcttt attttactgg
    26041 caatggtatt gattatcgga aaaagacaag ctaatcatgc gaaacaaaaa gaagttgaag
    26101 acgctaagag tcatatttct attgcaacca gtaatcctag taaagcaaaa actagcactt
    26161 ctgaaaccga agactttatt ttaaatccta ttgttgatgt ttccggctgg caactccctg
    26221 aagaaattga ttatgacaca ttgtcacgtc acatctctgg cgcaattgta cgtgtctatg
    26281 gaggatcgca aattacagct cataacaacg ctgcttttac aactggaatt gacaaatctt
    26341 ttaaaacgca tatcaaagaa tttcaaaaac gaaatgttcc tgtagctgtt tacagttacg
    26401 cacttggtcg tagtactaaa gagatgaaag aagaggcccg agctttctac aaaaatgctg
    26461 ctccctataa tccaacttac tactggattg atgtcgaaga agccactatg aaagatatga
    26521 ataaaggcgt aacagccttc cgagaagagc ttaaaaaact tggtgctgaa aatgttggtc
    26581 tctatattgg aacttatttt atggcagaac aagatatttc aacaaaaggt ttcgatgctg
    26641 tatggattcc gacttatggt agtgattctg gctattatga ggctgctcct aatacaacct
    26701 tagattacga tttacaccaa tatacctcac aaggttatct cagtggtttt aacaatgctt
    26761 tagatttaaa tcaaattgcc gtaacaaaag acactaaaaa aacgtttgag aagttatttg
    26821 gcaactccaa caattaagag gttagcatca tggctaatct ttttttatag tttacatctt
    26881 accaagaaaa actctaggtc aataatttaa aaccccttat ccttgacaag gagattatct
    26941 catcatataa tgaaaggact ataatatttc acaaaggagt gctttggctg agatcgcaat
    27001 tgcgaaatcc tgaggacctg atcttgttag tacaagcgta gggattgtga ccaataatca
    27061 atgattggaa agcgatactc tttttgtgca caaaaggagt tttttatgtc accaaacacc
    27121 aatgtcaaat accttatcga agctgctatt tttgctgcat tggcgatgac cctttcattt
    27181 attccagatt ttgctggctg gtttagtcct tcttatggtg ctattgcact ggttattttc
    27241 tctttgcgcc gtgggttaaa gtacggcatg ttggcgggtc tcatttgggg gctgcttcac
    27301 tttgtacttg gaaaagttta ctatctcagc atgtcccaag tctttattga atatatctta
    27361 gcctttacct ctatgggatt agccggtagt ttctctgata gtttgattaa aactttaaga
    27421 agacaacaaa ccttttttgc cgtttttctt gcaataatgg ctagtttact agccgttaca
    27481 gtacgttact tgtggcactt ccttgcagga atcattttct ggggcagtta cgcccctaaa
    27541 ggcatgtccg ctgtctggta ttcttttagc gttaatggta cagctggtgt cctaactttt
    27601 ttaataacat gtttaacgtt aatgattgct ttaccaattc atcctcaatt atttgatccc
    27661 aaagactaat ttttagtcat ttgaatctta cattaaaaaa atggtataat aatgttgtta
    27721 taccattttt tatgtttaga taaaggtaag gacttgatat ggctaaaaaa acaaaactca
    27781 aaaaaacctt agtagaacaa atcctcgata aggctaatat tgctcatcaa ggactcaagc
    27841 ttaatgcttt agaaggcgac tttccagatg atcttcaacc atcagatatt tacaagacac
    27901 ttgctctgac tggtgatcaa acaggtcctc taattggcat tattccatta acagaacact
    27961 tatcagaaaa acaattggca aaagtatcag gtaacaaaaa agtgtccatg gttcctcaaa
    28021 aagacttgca aaagacaaca ggctatattc acggtgccaa taatcctgtt gggattcgtc
    28081 aaaaacattc atatcctatt tttattgacc aaactgcact ggaaaaaggt caaataatcg
    28141 tttcagctgg tgaagttggg cgttctataa agatttctag ccaggctcta gctgatttcg
    28201 ttggcgcaag ctttgctgat ttaaagaaga gaaaatgaac actactgcca actttatctg
    28261 gtttcttttt taagtttttc gccttgatta agctagtctt tgtttagtat tattttgatc
    28321 tcaactgctt taacattgat cctgttaatc tttttctttt gtaaaggctt gatatcacga
    28381 caaattcagg tcgatttgtc ttaaatctaa tatgggcttt acactttaat cagaacctag
    28441 ctattataca cttatactac gcttttttac tttatctttt cactataggt attatttttg
    28501 cttggtgatg cctaaacttt ttctggttac ttttttattt ttagcgctcg catcagttat
    28561 ctctaaaagg aggcttaaat gaaattatat tttgtaaggc atgggaaaac cctttggaat
    28621 ttagaaggtc gctttcaagg cgctgggggc gattcgccat tacttgaaga ggcaaaagac
    28681 gaaattcact tacttggcaa agagttagct aaggtggctt ttgatgccgt ttatactagc
    28741 gaccttcaaa gagctatggc aacagcagct attatcttag atgcttttga ccaacagcca
    28801 aaactttacc acaccgacca gcttcgggag tggagattag gtaaattgga aggggctaaa
    28861 atagcaacaa tggcagctat atatccccaa caaatgctgg cttttcggga gaatctagcc
    28921 cagttcaaac cagatcagtt cgaggctgaa tcaatttacc aaacgactca acgtgtctgc
    28981 catcttatcc aatcgtttaa agataaacat tatcaaaacg ttcttattgt aggacacggc
    29041 gctaacttaa cagcaactat tcgctcatta ttaggttttg aacctgctct tttactcgct
    29101 aaaggtggct tagataatgc cagtcttact attcttgaaa ctaaggatta tttaacttat
    29161 gactgtttaa tttggaatga taaatctttt ctagaggtgt aaaaccacta gaaaataata
    29221 aaaaaagcta acacattgat ctcttactga caagacactc actttgctag ctttttttat
    29281 tattatctag tgggctatta tggtttcatc tatctggcat attttaagcg caaaactttt
    29341 tcttgttgct tggttaaccg aagcaagata accaccttgt caatgctcat gttgctttca
    29401 agtaaacgct ctgctgccat catcaagcca ttattgattc ccatctgtaa aattggattt
    29461 ttcttgtcat tgacatcaaa aataaattta ttatcaggta aatcaaagag tactttaacg
    29521 gcaccaaaga gctgttcaaa gttatcaata gccacatcat aaacaggctt agttcctggt
    29581 tttagctgac gacctctatg attaaaccac atggaatgcc aaccaccatt aaaggcaccc
    29641 atgatatcat tgtcataaga gtccccaaca tatagtgtgg tttgtgggtt catgtcaaat
    29701 tgttctgctg ccaggttaaa aatttctttt tctggttttt gaaagcctgt tgcttggctc
    29761 acaatgacac gcttaggatc aatataatca taaagcccta atttacgaac ttttttcagc
    29821 tgatgttctg tgggcccatt ggtaataatc cccataggaa cattctttga ttttaaaaag
    29881 tcaagggtca tgcgcatctc atctaacatg gtaatgttct caagttcgtg ctcatagact
    29941 tcttgaaaat gtactcccgc agcttcgtcg atttctcgat agccaaactc aagcagtgtt
    30001 tccttgcaac gccagaatcg gaaatattct gtggtccact cccctgccat tactcttggg
    30061 aatccaacat ctgaataatg acgaaagcga atataagctt gattcattac tgacatatca
    30121 aaatctggga agcacttttc catggcgatt cgataaggcg cttgctggtc gtaaattgtg
    30181 tcatccacat caaaaacaat agcagtaatc atgagtctct tttcttttct agtttaatat
    30241 cccaatcatt atactatttt ccattaggct tttcaatttt attttcaaaa aagtgccccg
    30301 ctgcagtcgc attttccaac gaaatatagg tgtattctag cctcttttat gatacaatgg
    30361 aaaggaaatc gtattggagg aaaatatgtc taatcaacac atcgaagaat taaatgacca
    30421 acagattgtc cgtcgtgaaa agatgatggc tctggctgaa caaggaattg atcctttcgg
    30481 taaacgcttt gaccgcacag ccaattctgc tgaattaaaa gaaaagtatg ctgataaaac
    30541 aaaagaagaa ttacatgagt taaacgaaac agctattgtt gctggccgct tgatgacaaa
    30601 acgtggcaaa ggtaaggttg gttttgctca tcttcaagac cgtgaaggcc aaatccaact
    30661 ttatgttcgc aaggactctg ttggcgaaga caactatgaa atcttcaaaa aagccgattt
    30721 aggcgacttt atcggcgttg aaggcgaagt catgcgtaca gacatgggcg agttgtcaat
    30781 caaggcaacc aagttgactc acctttctaa atcacttcgt cctcttcctg aaaaattcca
    30841 cggattaact gatattgaaa ccatttaccg taagcgtcac cttgatttaa tttcaaatcg
    30901 tgaaagcttt gaccgcttcg tgacccgttc caaaatgatt tcagaaatcc gtcgttattt
    30961 agacggtctt gatttcctag aagtagaaac gcctgtgctt cataacgagg ctggtggtgc
    31021 tgctgctcgt cctttcgtta ctcaccataa tgctcaaaac attgatatgg tgcttcgtat
    31081 cgcaacagaa cttcatttga aacgtttgat tgttggtggt atggaacgtg tctatgaaat
    31141 tggtcgtatc ttccgtaacg agggaatgga tgctactcat aatcctgagt tcacttctat
    31201 tgaggtttac caagcctatg cagactatct tgatatcatg aacctgacag aaggcattat
    31261 ccaacatgct gctaaagctg ttagaggtga tggccctatt gattatcaag gaactgaaat
    31321 ccgtatcaat gaacctttca aacgtgttca catggtagat gctatcaagg aagtgacagg
    31381 tgttgatttc tggcctgaaa tgactgtcga agaagctatt gcacttgcca aagaaaaaca
    31441 ggtcccactc gaaaaacact tcacaagtgt cggacatatc atcaatgctt tcttcgaaga
    31501 attcgttgaa gaaaccttgg tccaaccaac ctttgtcttt ggtcatcctg ttgaagtatc
    31561 acctttggct aagaagaatc cagaagatac ccgcttcacc gaccgcttcg aacttttcat
    31621 catgaccaaa gaatacgcca atgctttcac agagttaaat gatcccattg accaattatc
    31681 tcgttttgaa gcacaagcac aagctaaaga acttggtgat gacgaagcaa ctggcattga
    31741 ctacgacttc gttgaagctc ttgaatatgg tatgccgcca accggtggac tcggaatcgg
    31801 gattgatcgt ctttgcatgt tattaacaaa cacaacaaca atcagagatg tgcttttatt
    31861 cccaacgatg aaaccttaac ttttttaaga tttgtattca tatcttaaaa ccgataagtg
    31921 gcaatataac ataacgtttt attatctcta accagtcttc attaccatga agactggttt
    31981 attaacagta gcttatagaa agtgacttaa caagatgacc aaagaatata tctcctacat
    32041 tagtgctact atcttcttgc tttatggcct tttagctgcc aaatggattt ttcttgggct
    32101 aggcttaatt ttggtacttg tcggccttgc tgaccgcctc aattcaaaaa aataatcctt
    32161 ctattcgccc ctgtcctttt aacctagcga tgtcatcacc aggttaaaag gacaggggcg
    32221 aacgagggat tatgtttcga ttaaggtaac attacttacg aaaagcgtct aagatggttt
    32281 taaattcttc attagtaaga gtaatgcctt tccccatttt cgtatggtct ggactccacg
    32341 tgcggatatc ccatttcgct tctgcgccat taaagctgac gcggttcaat tcttttgtcc
    32401 aacctttatc attttctgat aaggtgagta aatgttcctc aatgttgaat gtaaattctg
    32461 ccattagttt tcctcctcat ctatactatt cgaaattaaa gtggaaaaaa tcatcttttt
    32521 ttcacttttt tttatgactc attctcctat tattctatca agttttgaga aaataagcta
    32581 ttgtgatatc caactttcaa aaaaaacagg ctctcttttc ccaactatgg tcgtatacca
    32641 tttggaaaaa gagggcctct agtatttctt gttactatgt tctaacagtt ttactggtgc
    32701 catctttttg atagaggttg acaaggcctt ccttgcaagc cctaatcata tctcctggtt
    32761 taacctctct tggcaaagaa atggttaaga gttccattgg atttggggca cgatcaatct
    32821 tttggccatc cgcatcatgt aagtccttaa caaccgtttc aaaatgacgg aaacctggtc
    32881 cataacattc aatccgatcg ccttccatga tgacattacg ctgacgaatg gtcgctgtca
    32941 tgctagctga gtcaaaggca actacttctc cgacaaattt atattgtgga attttgcggc
    33001 gagcaccaaa taattgttca ttttcagttg ggataccata gtaaaaacct gtagccaact
    33061 cgcgctgggc aaccttccac aactcgtcaa tcaattcctc tttgatagca taaaaagctt
    33121 ctgggctttc catgtaagca tctacagccg ccttgtaaca gttggttacg gttgagacgt
    33181 agtggataga tttcattcgg ccttcaattt ttaagctatc aaccccattt tcaatcaggt
    33241 caggaatatg gtcaatcata cacatgtcaa cagaggacat agaatagtct tctggaattt
    33301 ccccttttaa ggagcggcgc tctcctccaa atggcatgtc atacaaatca tacttccagc
    33361 ggcaagactg tgagcagccg cccctgttgg catcacggtg actcatgtgg tttgacaaaa
    33421 cacagcggcc tgaataagaa atacacatgg ctccatggac aaaggcttca atttccacat
    33481 ctgtccgctt acggatttct gctaattcag ccatattaac ctcgcgagct aaaacaactc
    33541 gggtcaaacc catggctttc caaaattcaa aggtctcgta attggtagat gaagcttgcg
    33601 ttgacaaatg aatttccaaa cctggggctt ctgttgaaca aataacaatc aaggctggat
    33661 ctgaaacaat gaccgcatca agccccatat cacgcagttg acgaaaccac tcgcccgcac
    33721 caatttcgtt cccttcgtgg gtaaccatgt tagcagcaac atagacctta gctccacgcg
    33781 catgtgcata atcaatgcct tcttgcaatt cttccataga gaagttacca gcgcggcttc
    33841 ttaggccata ggcctgccct ccaacaaaaa cagcatctgc gccatagtca atcgcaactt
    33901 ttaatttttc aagtgttcca gcaggtgata agacctcggg acgttttttc atatgtgaca
    33961 tgtgatattc tttctatttt caagataggt agattacctg tgtaatggtg tcataaccct
    34021 gtcttgccct gaaatagtaa actcactcaa gacaaggatt acttatttaa cggtttttgg
    34081 atcgaactca taaaagccag tatctaatcc acggccagct ggatgatggg catgcactgc
    34141 ttgatcaagc ttttcagctt cttcttgggt aaattgccca gcttctaata aggttttagc
    34201 ctgaataaac aatttagtaa tagcgacaaa atcatcacct ggacagtaaa tgccatctag
    34261 cttccaatga gttaagccat gcgcatacag ctcacccaat ttagacatca tgtcgatatc
    34321 gttattaatg aaaatatgag tgccatgatt gtcttcataa atggagtaat ggctgctagc
    34381 atctcctggt tctgccaaga aaagtcctcg ttcacgacta acctcatcat caatctttgt
    34441 aaaatggtaa taattttcta gcaagggacg tttcgagtga tgaatcaccg aggcgccgta
    34501 aactagcacc tctgctggaa attccaaatt ttcagctaag gtgaataact ctgctgatgg
    34561 gatttccctt gctaaaacac tttcaacagc accatgttgc ccccagaaat ttacctgacg
    34621 gctagaagtc acaaaaacag aggtatcata aatcagttta aagttatagc catccctttt
    34681 attgacataa aacacacctg catcaccaac cacaagataa tcaacagcaa tctctatcat
    34741 taagtctaaa aagggtttga tctgatccat catatcttga tgcatcaaag cattgcaagc
    34801 tactgtcaac tctttgcctg catcatgcac tagtttggca atttgtctca attcatcata
    34861 agaaaaatta tggggaagac gtaacccgta attggcttca ccaacataaa tacgatcaac
    34921 accagcagct aataaagctt tgacttgctc aatgctttca gctgtggctg taataattat
    34981 tttttccata taagctttat tataccaaaa attttaagac cgtaagcatc tttcttgcaa
    35041 aagcccaaac gttaagctag tccccttact gttatagcat gataagtcac ttgtcattag
    35101 taaatctttt caaatctttt aaaaaaagat gacaagaaga gacttttatg atagaattac
    35161 ttagtatgtt aaggaaagga gaggactatg cctgcaccgt taaagaagca taattcggtt
    35221 gaacaggatg attcttacca agaatctcaa agtaaatttc gagattttca agagttcaat
    35281 ggccaaagtg caaagctaaa agaattagtc ttctttgctc gtatcgctag tttcagcctt
    35341 attaccgttt tatttgcatt tgtcctgctc gtaatgaatt tagcgccaat gtttgctttc
    35401 ttatttgcaa gcatcatcag cttaggcatt acttccttat tagccaaggt tatcaaatca
    35461 ttactgatgt aacttccaga gtccattttg tatgactctt tttcttttgc caaaaacaaa
    35521 aaaagattga agccacaatc cccccttctt cagttagcct aaaactaacc atcgggacta
    35581 gtgatcagat ccttcaatct tttcttcttc tatgttttaa gtcgttttag ttagtgtttg
    35641 tctaatgtat cactaacagg ctcatcttgt tcagtatagt caatgatgat gtcgtcttca
    35701 tttaaatcaa tgataacatc atcttgcttt tctttcgctt caacttcggc aaaggtttct
    35761 tttgtttttt gcacgaaagc tgttgtttta tctttgagca agtctaacat gtcctcttta
    35821 gttaagtcac cagaagccaa cttatctttc acatcataga aagtgtcacg tgctaaatgg
    35881 ctgtattcac tacctttttc tttagcaaac tggtggtaat catctggact ttctttgtag
    35941 gcttgataag ctttttcagc acgatttttc aaagccttgc ctttttctgt tgataagaag
    36001 taagctgccg ctactcctga agcagctcca atcactaagt ttttgaaact tttattcatg
    36061 cttttctcct ttttttccaa atacttttga ggctacttta ccaactaatg ctaattttcc
    36121 agcttttgaa acattacctg tagcattagt tgctttttgc ccaaaatgcc ttgcttgact
    36181 atttaaatct gaaagacttt ctgacaaatc agcaatagca acaaacagtg gatcgatggt
    36241 tgctacttta ccattaacat cttcaacaag gatattagct tttgctaaaa tatcattagt
    36301 ttgatgaagt gtcacattaa catcacttgt caatacagaa atcgtttttt tggcttcatc
    36361 aattgtttct gagactttct ttaatacaat aatcaagaaa atcaccaaag caacaaatgc
    36421 gagtgcaata atcatcagtg agattccaac taagtccata agtttctcct ttttctatcc
    36481 ttattcttga taataagaaa ttcctttttg acgacgtctt tttatgacaa agattaagcc
    36541 aataataatt aataaggcag acacatattg ggagatgcga atacctaaaa acataagact
    36601 atctgttcgc ataccttcaa tgactagtct tccactacca taccaaatta agtaaaatgc
    36661 aaagatttct ccatctaata gactttttgg cttacgacgc cacatcataa taatgacaaa
    36721 tcccaaaaga ttccaaagtg attcatagag aaaggtcgga atgcggtaac ttccctctat
    36781 aaacatttgc ttttgaataa agcttggtaa gtaatttaac tggctcacag ctttaccata
    36841 ggcttcttgg ttgataaaat ttccccagcg accgatagct tgagcgacca tgacacttgg
    36901 tgcggcaata tctaaaaaat gaatgggatt gagcaccttg ttataacagt aagccaaaag
    36961 tacaagagct cctgtaatga gaccgccata aatagcaata ccgccattcc aaatggctat
    37021 gatttcatct aaatgcttga cataataaga ccattcaaaa ataacatagt aaattcttgc
    37081 accaacaata gcaagtggaa aagcaatcag aataaaatcg aaaatagcgt cagatgatat
    37141 tccttttttg ggtgcttctt ttgatgctaa gtaaaccgcc aaaacaagtc ctgacaagat
    37201 acatagagca taccagtgga tggctagtgg accacatttt aaggcaatgg gattgatcat
    37261 tgactcacct catttttggt gattagttga gttaaacgat cttcaaaagt ttttgtagca
    37321 tcaaagccca tttctttagc ccgatgattc atcgcagcgg cttcaataac cactgaaaca
    37381 tttcgacctg tttttaccgg aatacgaata cgagggattc tcactcctga gaaagttatc
    37441 tcctcattac cgtttccgag acgatcaaaa actttaccag cctcaaagtt ttcaaggtaa
    37501 atggccaatt gaacttgtga tgagtccttc acagcactag ctccataaag cgacatcaca
    37561 tcaataatac ctaccccacg aatttcaagc aagtggcgca agatctctgc tggctctccc
    37621 caaagggttt cttcatcttt ggcatagaca tccacacggt catctgcaac caaacgatgc
    37681 cctcgcttaa ctaattctaa accagtctca cttttaccaa ttccagaatc cccttggata
    37741 agaaccccca taccataaat atccattaaa acgccgtgaa cactagtacg ttcagctaaa
    37801 gaagcgtcaa gaaaataaga catttctcca gctaagcggc tagttgaaac acggctactt
    37861 aaaagtgaaa taccttcttc ttttgcagct tgaaccattt cttttggaat ggctaaattt
    37921 ctagagacaa ccactgcagg agtgtccttt ttaaacatct cttttaaaac agaataacga
    37981 ttgtgagaag tcatctgtgt aagataagac cactctttca ttccaaatag ctgcaacctt
    38041 tctggagcat aataatcaaa ataaccagtc atttcaagac ctggacgtga aatatctgat
    38101 gttgttatct cttttgacaa caagttatct gtagcataaa ccacatcaag tttaactttt
    38161 tgcactagca tctttacagt aacggtcata atttctcctt tttcaatatt ataacacaaa
    38221 tcgaccgtta gacccttgca aatactcatt ttttcactac taaatgagaa caacgacacc
    38281 aaaaatggtc ttagctctat taaaaactag gttttatcat ttagagatat gagtcaaaaa
    38341 taagacaatg gcaaacaaat actttactag tatcattgag caattagtgc tatggtattt
    38401 aaaaaggtat catcttacta agtcaaaaag caaaaagcct catcatagct gataagaccc
    38461 ctcgcttact tacatatcaa aacattttat tatcatcagt taatcacatg gttgctctta
    38521 cgtgatgaat tatcatttta actgattgtt taccagaacc agccatcttc ttcttcattt
    38581 aagacatcag cgtctttacg acgacgagga cctcggccat aacgttcttc aagcaagtct
    38641 tccttgtaag gtaagaagat ggccaacaaa atataaagca aaactccaaa accagttccg
    38701 taaataagaa gagccgctaa gacacgcgct agagcaagat cccaaccata cttatctgct
    38761 aaaccagcaa tgacacctgc aaccaagcga ttttttcgct gtttatagaa tttagtttcc
    38821 acgtttcttt acctcctcat tctatgatac tagtttacat tgtttttcgc aaaataaaac
    38881 cagtcttacg actgattttt ttccataagt ttcccgtggc aatttccaca aacatattta
    38941 gccagattga tacgcctttt tcgttgataa acctgcccac aggtttggca actataatga
    39001 tgattagtct ttgatttaga gctagttggg acataacgaa gcccgtttac ttgagctagc
    39061 agatctttga aatccctatc tttatgatgg taccctcttc cttcaaaata aagatggtaa
    39121 tggcagagct catggcgaac aattttccga aaaataagct caccgtgctc ctcaagcatc
    39181 ctagggttaa aatccaaatg accatctttt ggaaaaaagc gaccgccagt tgtttttagg
    39241 cgcttgttcc aataagcctt gtggtgaaat ggtttgccaa aatcagccag ggaaacttct
    39301 tggacataat tagtgagtgt cacgcggtgg caataggctg agattgacct tgtggcggtc
    39361 caagtcaatc ttagagaccc aaacagttac caagtcaccc actgaaacaa cttgactagg
    39421 gtggttgaca aaggttttgc tcatttcaga aatgtgaata agcccatctt catgaacacc
    39481 aatgtctaca aaagcaccaa agtcaacgac gtttctcaca gttccctcaa gcttctggcc
    39541 aatttccaaa tctttcaaat caaggatatc ttgacgtaag attggtgctt caaagtcatc
    39601 acgaaggtca cgacccggtt taaggagatc agcaatgata tctttaaggg tttcctgccc
    39661 aatagccaat gtttctgcca tttggggaac ttgaactgct gctaaagttg ccttggcagc
    39721 gtcgtccaag tcctgaatac caagtacctt aaagagttct ttgactgctg ggtaggactc
    39781 ggggtgaact cctgtgttgt ctaaaatatt tttggctcct ggaattctga gaaaacctgc
    39841 tgcttgctca aacgccttag ctcctaatcg aggcactttt ttgatgtcag cgcgtgatgt
    39901 cagtgctcca ttttcttcgc ggtatttgac aatattttct gaaatcgttt tgttcaaacc
    39961 tgacacatgt gctaataaag atggactagc tgtgttcaca ttaacaccga cttggttaac
    40021 cacagtatcc acaacaaaac caagattctc actcaacttt ttctgactca catcgtgctg
    40081 gtactgaccg acgccaatag atttaggatc aattttaacc aattctgcta gtgggtcttg
    40141 caagcgacga gcaatagaaa tagcagagcg cttctccact gtgaggtctg gaaactcatg
    40201 gcgggctaac tctgacgctg aataaacaga agcaccgctt tcgttaacga tgacatagga
    40261 cgtatttggg aaatctttca aaacgtctgc tacaaaggct tcactttccc gactggctgt
    40321 tccgtttcca atggcaataa tatcaatctg gtaagtctca atgagctgag tcagtgtttc
    40381 tttagctgct tgaatcttcg tttggctagc tggtgctacg ggataaataa cctgagtagt
    40441 caacaatttt ccagtctgat caacgatagc caattttgca cctgttcgaa aggcagggtc
    40501 aaacccaaga accattttcc cttttaaagg agacactaac aaaagatgac ggagattttc
    40561 agaaaagagg tggatagccc catcttctgc ggcatcactg agttctgaac gaacccgtct
    40621 ttccatagct ggaacaattt tctttttgat ggtctgattg atgacttctt caatataagg
    40681 gttggtttct ttgaaccgca cactgaaaaa gcgttgcatt ttctccaagt tatgctcaaa
    40741 agacactttt aagatgccta acttttcgcc acggttaagg gctaaagtac gatatccttg
    40801 catgttagac acttggtcag aaaaatcgta atagatttgg aaaacctttt tctcatccaa
    40861 ctgctcatct ttaagcgttg atactaagcg gctgtactgc caaatctcat tgtaggtcca
    40921 agagcgtaat ttagcatctt ctgacatggc ctccacaagg atgtccacag ctcctgctag
    40981 agcttcttgt gggctggcaa atccttctgt gacaaagggt tctgctgctg tttcaaggtt
    41041 ttgcgcattt tgtaaaatca aacgtgctaa tgggaacaag cctgcttcac gcgcaatcgt
    41101 cgcttttgta cggcgttttt ccctataagg caggtacaac tcttccaaat cagcgagttt
    41161 ctcggttgct tcaatactcg ttcgtaactg atctgtcagt tttccctgtt cctcaatttt
    41221 agcgagaatg gttgctttgc gctcattcag ggtagtgaga gacttatcca tatcaataat
    41281 ggacttaatc accacttcat ctagatttcc tgttacttct ttacggtaac gtgcaataaa
    41341 gggaatggta ttgccttgtg ctgttagggc aagcacctgt tcaatttgat ggagactaac
    41401 tgacaaagcc tctgcaatgt tgtgattatt gttattttcc ataatattgc tattataaca
    41461 caaaccatgt taatgcaaaa aatgatagcg aaacattgtc ctaatataaa tttgcgtaaa
    41521 gaatcaaaaa aagctacttt tagtaaataa ctgacgaaac cctaaataac aatacctaat
    41581 tttaaaaaag aaagaagtaa acaacacttc cgttttggca ttgttctcaa atgatagtat
    41641 aatagactta tcttgaatga aagaaggtca tagatatggc aattacccat aaaaaaaatg
    41701 atgaacttga aaaaatgcta gcaggctttg catcaatccc tagttttgat aagcctttgg
    41761 aagtcaatac tgatggtaaa ctagcgacca aagaaaaaac gacagaacaa acaaaaccaa
    41821 gcaaaccata gctagtttgt ctcattctct taacatatcg tccattcgtt taaactgagt
    41881 tgagagattt ttagcgatca ggctaacaaa acgtatcagt cgaggctgaa cattcgtgtt
    41941 tcagcctcct cttttatcat ctagaaagga tatggtgaat gtcactcttt tccaaccttc
    42001 ctcccagtgt cttgcaatgg tttgcgattt ttatgtccat tatcattgaa gctcttcctt
    42061 ttgtgctcct aggaactatt ttatctggtt gtattgaagt ctttgtaacg ccagaattgg
    42121 ttcaaaaata cctacctaag caaaaatgct tgcgcattct gtttggaacc tttgttggat
    42181 ttgtttttcc ttcttgtgaa tgcgggatta ttcccatcat caaccgcttt ttggaaaaaa
    42241 aggtgcctag ttatacggcc gtcccttttc tggcaacagc gcctattatt aatcctattg
    42301 ttttgttcgc tacttattct gcttttggga attctttgcg ctttctgata cttcgcttgg
    42361 tcggtgctgc actagtagcc attacacttg gggtaatgtt agcttttatt gtagatgata
    42421 acattctcaa ggataatgct caacccgtgc attttcatga ttattctcat gaaagcttgc
    42481 caaaacgcat ttatctagca ctggtacatg ctattgatga attcttcgac accggtaggt
    42541 atctcgtatt tggaaccttg attgcctctg ccatgcaaat atatgtccca actcgtgtgt
    42601 tgacaacgat tgggcacaat cccttgacag ccattttgat catgatgctg atggctttca
    42661 ttctatcatt atgtagtgaa gccgatgcct ttatcggagc ttccttatta tccacctttg
    42721 gagtggctcc agttcttgcc tttcttttaa ttggtcctat ggtggatatt aaaaacctta
    42781 tgatgatggt aaaggctttt aaaggacgct tcattgtcca atttatcggc gtatccgttc
    42841 ttatgattgc cgtttattgt ttacttgtgg gggtgctcta atgattcgct ttttaatttt
    42901 atctggctat tttgaactaa ccatgtatct ccagctgtct ggcaaactgg atcagtacat
    42961 caatgttcgg tattcttacc ttgcttatat ttccatggtt ttatctttca ttttagctct
    43021 tgttcaactc tatacctgga tgaaaaacat taaggtacat agccatttaa ccggaaaaat
    43081 cgcaaggctg accagtcctt ttatcttggt ctttcctgtt ttgattggtc tccttgtgcc
    43141 aacagtaacc ctagattcca ccacggtttc tgccaagggt tacacttttc ctttggctgc
    43201 gggagcctct aaaacgggag tcagtgatga cggtaccacc attcaatacc tcaaacctga
    43261 caccagcctt tactttacaa aatctgccta ccaaaaggag atgcgtcaag aactccataa
    43321 atataaaggc aagaaaccgg tcaccattac cactgaaaat tatatggaag tgatggaatt
    43381 gatctatctc tacccagatg agtttgttga tcgtgacatc caatacactg gctttgttta
    43441 taacgaaccg ggccatgaca actaccaatt ccttttccgc ttcggcatta ttcactgtat
    43501 tgccgactca ggagtgtacg gacttttgac cacaggtaat caaaccagct accctaacaa
    43561 cacatggcta acagttaaag gtcgccttca tatggaatat gataaaaact tagaacaaca
    43621 tctacctgtc cttcaacttg ctgaggttca tcaaaccaaa gaacctaata atccttatgt
    43681 ttaccgcgtt ttttaaagac taataaaaaa gcacttgttt tttatcaaaa caaatgcttt
    43741 ttgcgtttta tcagttagca taggaacaga gtcatcatct taaacaagac ctattgagaa
    43801 aaaattatcc tcaaggtaac gtccattggt ttgaatgact tgtcggtacc aatcaaatga
    43861 ttttttctta tagcgtgtga attgaccagt accatcatca tttcggtcaa cataaataaa
    43921 accgtagcgc ttacttaatt gggctgttga catagagaca caatcaatac agccccaagc
    43981 agtgtaaccc atgacctcaa cgccatcttc aatcgctttg gcaacttgta cgagatgctg
    44041 actcatgtag tcaatgcgat aatcatcgtg aaccgtcatg ctgccatctg cggtttgcac
    44101 cagctgatcc tttgcaccta agccattttc aacaataaac aaaggaatct ggtagcggtc
    44161 atagtactga ttcaagacca atcgcagacc aattgggtct atctgccaac cccactccga
    44221 agattctaaa tatggattgg acaaaccacc tagaatattt ccttgaccag atgtgtaagc
    44281 ttcaggattg tgagcttgtg tgacactcat gtaatagcta aaggatagaa aatcaaccgt
    44341 atgttccgct aataattcct tgtctccgtc ttcaaaaaca atctcaatcc cgttttcttt
    44401 aaaatacgac ttaatatatg aaggatactt acctctcaca tgaatatctg aaaataagag
    44461 attaagattt tcaaatgcat gcgcagcaag tatatcacga ggatcagagg tcattgggta
    44521 agcaggcatc gccaaaatca tacacccaac tttaacatca ggattgattt catgcgctag
    44581 ctttgtgaca ctagcagatg ctaccaattc atgatgaata gcttggtata aatcttgcag
    44641 gctcagcttt tctttttctg tcatgatgcc accactggta aagggcatgt gtaaaatcga
    44701 gttgacttcg ttgaaggtca accagtattt gactttgtcc ttatagcgtt ccatgactgt
    44761 ctgagcaaag cgctcaaaaa agccaatcag acgtctatct gtccaaccat tataggcttt
    44821 ggccaaatgc agaggtgtct cataatgcga caaggtcact aagggttcga taccatagtt
    44881 caacaattca tcgaataagt catcataaaa ttgcaaacct gcttcattgg gctggtcatc
    44941 gtcaccattt ggaaaaatac gagaccaagc aatagacgtt cgaaagactt taaagcccat
    45001 ctcggcaaaa agagcaatgt cttctttgta gcggtggtaa aaatcaatcg cctctaaagt
    45061 taaattatcg ctggtaggac tatctgtcca ttctcctagt ccaccatttg gtagaacatc
    45121 ttgtacggac aaaccttttg cgtctgcctc aaatgctcct tccacttggt tggcagctac
    45181 tgcgccgccc cataagaaat cttttggaaa aattcccatt ctccctctcc ttttaggtta
    45241 taaaatgact aacaaagcgt cctctttagt caccattttt ttgtcatctt gaataataat
    45301 ctccaactgc tcagccgaat tggtcacgac cacaggactg atgagtgaat agccttttga
    45361 agtaatgaaa tcagtatcca tttttagaag tgcctggcct cgtttcacga catcgccaac
    45421 agacactaac tgctcgaaac cttgcccttt taactcaacc gtatcaatac cgacatgaat
    45481 caagacttcc acaccacgtg cgttttttaa ggcaacagca tgcttggttg gaaagaaagt
    45541 gatgacttca ccatcaaagg gggcatagac ctcaccttcg cttggtaata tggcaaatcc
    45601 ttctcctaat aacttggaag aaaaggtttc atcaggaact tctgatagaa aaagtatctc
    45661 acctgtcatt ggagcataca acgtttgttt ggttgacaag ccgctcttaa cttgtgacat
    45721 atctgctgca acactcactt gctttgggga ctcttcatca attcccatga accaagtcaa
    45781 actgaaggct aacacaatcg tcgcagttcc ggcaatcaaa gcatttgtaa aattagctcc
    45841 gcctgatggg ttgatgtact gtggtaaacc aataatagaa ggtacgacaa aggtataaga
    45901 agcaatattg acaaaaccaa taaaggctcc aaccagacca cctgaaatca tggctgcata
    45961 gagtggcttt ttaaatttca gtgtgacccc ataaagtgcc ggttccgtga tacctgccag
    46021 caaagctgaa atccccgcgg caagggcaac ttgacgtgtt tgtttctgct ttgttttaaa
    46081 ggcaacagcc aaagatgcgg ctccttgagc caaattagaa gccaacattg ctggtaaaat
    46141 caagacatct ggtgttgcga ccgaagcggc caaaaagatt ggtgcaaaag cccagtgcat
    46201 ccccgtcatg acaacaagcg gcataatcgc tcccaaaatg gcaagtgcta gccacggagc
    46261 cacatgataa atagcgagca tggtattaga taacccttga ccaataatca caccaagagg
    46321 acctacaacc actaaagcca aaaagccaga aatcaaaatg attaaggttg gctgtaagaa
    46381 gcttttcatc acgcttggca ccaagcgatt gacccatttt tcaatgtatt gcatcaagta
    46441 aaccatcatc aaaatgggaa taacagatga gccatagcta gcaggagtga ctggtgctcc
    46501 aaataaagtc aatggtttac cttctgctac cattgcaaca aaggcaggat gcaataaaat
    46561 ccctgcgatc gtcgctgcta aaacaggtgt caccttaaag cgcgccgctg ctgaataggc
    46621 aatcatgaca ggcataaaat aataagccgc atcgccaaag aagttaataa aggcaacggt
    46681 ttgagagtcc gcactcgcta agccaagcat aggaagcaag atccccacca ctttgagcat
    46741 tccaccacca agaagggctg gaatcagcgg tgtaatcacg ccagcaatgg tttcaatcaa
    46801 gcgctcaagg atacttcctt tcgcttttga agaatgatct tcatcttgat tgtcaaaatg
    46861 ccctaggctt aaaaaggctt ggtaataatt attgacatca ttgcccaaga taatttggta
    46921 ctggccgttt ttgcgcatca cgccaatcac atttgaaatg gctttgactt gctgatcttt
    46981 aactttctca tcatttttca gtactaagcg tagacgtgtt acacagtgtg tcacacgttg
    47041 aatatttgtt ttgccaccaa ccgccgctaa aatagccttg gcagtttctt gatacgtcat
    47101 attaagtctc ctttaaatgt ttcactaaac gtttaacatg aaccgtcaaa tacaaaagtt
    47161 cgcttgaatt aaggtgatag ttgtaccgct tttttatctc ctcactaata tctaagacgc
    47221 accgatattc tttagggtat ttcgttttca ccactataag cagttccgca tcatcatcat
    47281 cgtaagacat ctcagataac acacgttgag caaataattt aatatgggtc ataaagcggt
    47341 aataatcgat ggatgtgtca tccaattctg ttttgaagtc tgttttgatt ttttgctcaa
    47401 tataagaaac aatctccgtc aggcgatgtg gctccttaaa aggagtgtcc aaactagcat
    47461 tgacaaaatg catggcaata aaagctgctt catcaatagc tagagtgact cctagattac
    47521 gctcaattag ctctaaggct tttaccccta gactatattc atcaggataa tagcgttgaa
    47581 tttcccaccg tagtgggtta tgaatcaaca ttccttgctc atgcctttca atagcagagt
    47641 gaatatgatc cgttaaatta atatagagaa tttcatctaa ggttttgcct aatttaattt
    47701 tacctagatt gataattctc tctgagcaag caacaacttc ttgtggcacc gtaataaata
    47761 actctgtgaa gcgattcata ttgtcactat tttttaaaac aaatgatgtt tcgatagcat
    47821 taagctcaat actatctcca actttttttc caaaggcaat cccttttccc atcaataaaa
    47881 tatctaatcc ttgatggttg gtcgaaatcg ccgcattatg gtttaaaacg cgtttaatca
    47941 acataaaagt cctagtcctt tagtatcaca ataaaaaatg acctatccaa aagctcgcta
    48001 aaaagcactt ttcgaatagg tccctgctca caaaactgtg ataacatcct ttaatattct
    48061 gattgttatg tctctagcct gcttacctga agtaatcaca tctgagaacg ctttaatgtt
    48121 atcatctctt taagattctg tcaagcgttt tcaaaaaatt ctctgaaaga gcaactattg
    48181 ttattcgtat ctattgattt agcaaaaaag agtttctgac aattttaaga ttatatgata
    48241 caataacaat cgattagata aaggagttat catgtcacat catcaacaaa ccgtttcaaa
    48301 acaaacaatt atggcgatta tcgccatagc actcattggt ttttcaggaa ttttgtctga
    48361 aaccagtatg aatgtcacct tcccgacact gatgtcagtc tatcagttgc ccttaaatag
    48421 cttgcaatgg atgacgacca tttatttact agcagtggcg attatgatga ccacttcggc
    48481 tacactgaaa aaaaatgtgc gggaaagacc cctctttttt atggccacag gtctttttac
    48541 atttggcacc atcttggccg ttctgaccca gtcctttgcg atcatgttgc tagcccgcat
    48601 ttttcaaggc attggtactg gtctggtaat gcctcagatg tttaatatta ttttagagcg
    48661 tgtcccaatg cataaggtag gtctatttat gggatttgct ggtcttatta ttagcttagc
    48721 acctgctttt gggcctactt atggaggctt tatgattagc cattttagtt ggcaatggat
    48781 ttttatctgt atactccctg taccactgat tgcaggtatt ctagcttatt attacctcga
    48841 agattctcca gtaagcgaaa aagtaccctt tgactggttg gcatttattg cactatcgat
    48901 tagcttaact tctgccttat tagctattac tagtctagaa aacggcagtg ttaatttgta
    48961 ttacttaggg ctttttattc tcagctttat cctcttcctc tacaagaatc tcacagctaa
    49021 gcaacccttt cttgatattc gcattctcaa aattccctct ctaacctttg gcctgattcc
    49081 cttttttgtc ttccagctga ttaatttagg cataaatttt ctaacgccaa actttattgt
    49141 catggaaaag attgctaata gttctcaagc tggtatggtg ttactacctg gtaccttact
    49201 cggagctcta ctagcacctg cttttggtaa actttatgat caaaaaggag caagactttc
    49261 gctttattta ggaaatgcct tatttagttt atcattgatt attatgacac ttcaaacaag
    49321 acattttatg cttttaccat tcactctttt atatatttta ttcacgtttg ggcgtaacat
    49381 gggctttaat aatagcttag ccacggctat tcgagaattg cctgccgaga aaaatgccga
    49441 tgccacggcc atttttcaga tgatgcagca atttgctggc gctctaggaa ctgctatggc
    49501 atcactgata gcaaatagtc aagcagaatt cacaagcggt gtccagtctg tctaccttct
    49561 ctttactatt tttgctctac ttgattttat ctttttcttt gctatgtttt accatttagg
    49621 gaaaaaagga ttagcctaag atgacatact aaaaaccagc ctcgttcaat aaaacgagac
    49681 tggtttttgc tgttataaga taccttccaa aaggcctttc ataaagtctt ctgagtggaa
    49741 ttctccaata tcatccactt tttcaccaaa tccgataaac ttgactggaa tgtctaattc
    49801 ttgacggatg gctaggacta caccaccttt ggccgtgcca tcaattttcg ttaaaatcaa
    49861 acctgttaat ggtgttattt ttgaaaattc cttggcttgg ctaagcgcat tttgtcctgt
    49921 tgacgcatct aaggccaaaa gcgtttcatg aggggcatct ggtagcacgc gcttaatgat
    49981 acgacccatt ttttccagct ctgccatgag attttctttg ttttgcaggc gaccagccgt
    50041 gtcaatcagg agaatatcta caccttttgc cacagctttt tccatcccgt caaaaacaac
    50101 agacgctgga tcagcctttt cagggccagt aatgactggc acatctactc ggcgtcccca
    50161 ttcgactagc tgagccacag cccctgctcg gaaggtatct gctgccacca acatgacttt
    50221 tttaccttct tgtttgtaac ggtaagccag cttcccgatt gaagtcgttt taccaacccc
    50281 gttaacacct acaaaaagca taaccgtcaa gccatcttga taattaatgg cttcattata
    50341 acgcccatct ttttcataga tatctaccaa tttttccaca atcacacgtt tcaaggcatc
    50401 tggttttttc gcattttcca gtttggcttc ataacgcaac tcctctgtca aagttgtcgc
    50461 cacatgtaca ccgacatctg ataagatcag catttcttcc aagtcttcaa agaattcttc
    50521 atccactcgc ctgaaattgg caaagaaact gttcagacga gctgagaagc cagtccgcgt
    50581 ttttttcaag ctacgcttgt atttttcttg atctgtctca ggaatggtat cgtgggttgc
    50641 cttgttttga gaagcttctg ctgaggtaga ggcctgattt tcttgtggaa cttcttctgg
    50701 catcactgga accgttgccg ctgctttttc ttgaaggctt ttttcaagag cagctttacg
    50761 acggtagtag tcttccataa cctgttggct actggattgc tcttttgaag tgtctactgc
    50821 ttcttcattc gccgaatcat ttgaggcatc agcttgggct tgttttgttg gaaactgttc
    50881 cacaactggc tggtcaacaa ggtcttttgg ttctgatgcc gtagattgac taagttcact
    50941 taccttaagg tctgttttgt cggcagcaaa ctcattggta tcttctgatg gatgattact
    51001 attgtcacct gtttcttcct caaccagtgc gtttactgaa gctgcttcgg gaccattttc
    51061 caccgaacct gcgccctctg aagaaacgtc ctcttgttga accgcctcaa tcttgtcttg
    51121 ctcattggct ttttcagaaa gctcctcttt ctgagttgtt tctgtcaaaa gattttcttc
    51181 taacttttcc tcagctacct tcggggtttc ttttttccca aataaacgat caaataatcc
    51241 cattaactct cctcttctaa aataaatgtc ttcacagctt ctgcaactcc agactcatca
    51301 ttggtcaagg tggtcacggc atcggcaacg gctttagctc ctgaaacacc attagccata
    51361 gctactccaa gtcctgccca ttctaacatc gcaaagtcgt tagcttcgtc tcccatagcc
    51421 atgacatgtc tagcgtcaag gccaaggtgc tggcaaagca agtttaatcc aaaagcttta
    51481 tcaatgcctt ttggcatgat ttcaaaaata atatctcgtg atttaaaggc ttcaaaatcc
    51541 tcaaataagc ttggggatag ctttataatc tgctgatcca aaaagtctgg atcggtgact
    51601 gtcacaattt tgttataggt aatgtctttt ggtagttccg ctacagatgt cacctcaata
    51661 aaggtcaaca gtgggttagc tagatggtac tgcgaatgcc taccgtcctt acttggaatg
    51721 ctatacacat ccccaccact gataatatct gttggtaagc caaccgcctc taaagcttgc
    51781 tgaatctggc agacctggtc aaaactgaga gaactcttat ccaaaacctc ccctgtattt
    51841 cgctgaacca aacccccatt aaaggtaata ctgtagtcat cgtggtcaag caagtccaac
    51901 tcttctagca agttaccgat ggcctttaga gggcgacctg tggtaataac caccttaacc
    51961 cctttttctc tagccgctgc taaggctttt ttattggcat ctgtgacaat tttttcagtg
    52021 ttgtagaggg taccgtctaa atcaagcgcc aaaattctaa tattcatgag ttacactagt
    52081 ccttttaaat acgttagtac tgctccgtca ttacagtggc caatgacttg gtctgaaatc
    52141 actttgattt caggtcttgc attttccgta gcaatagccc taccagcaaa ctccaacatc
    52201 tggtaatcat taaaattatc cccaaaagca atcgtttctg ctttcttaat gcccaaggct
    52261 tgacaaagat gctccatacc aaagccctta ttcacctctt ttaagataat atcaatggaa
    52321 tcaaagccgg tggtcactgc agtggcataa gggagggctt gattcaacca atcgcttcct
    52381 tctaagacgg tatggcctgt gaagttggta gaaactttaa aaatggcgtc attctccata
    52441 tcttcaaaac cattaataac cttaacatta gcatagtaat gttttgtttt ttgaatgtac
    52501 tcttctgatg cgccttttaa aatataggct gccttttgcc cagaaaaaac catacctgtt
    52561 tctacatagt aaggattggc taaaaccttt tttgcaactt cggtatactg ctctttggtc
    52621 atcatatctg caaatagaat ctcaccacgg tattgaacca cggaaccatt ttctgcaata
    52681 acagcaatct gatccaaaaa gggctcaaag agctgatcaa tggctaagag cgagcggcca
    52741 ctcgaaaccg caaataaaat gcctttttcg gctaactttg gcaagagcgc agctagttgc
    52801 tcttgattat aagtaccatc ttcagctagg aaggtaccat ccatatctgt tgctattagt
    52861 tttatcatac aatgtctcct ttttttactc taggggggtg caaacgccat ttagggtgtg
    52921 cactttttaa cgatttaaat aagccccatc atttctgcat tctgttcaat ttttcttatt
    52981 atatcataaa aagcagcttt cattccattc gtaaaaaaca gccagattat atttcgataa
    53041 cctgaccgtt tttgaagtga actgctactt ttttattttt ataaatgacc actggatgta
    53101 tactataaaa gtagacaaaa ctttgtgtgt tacaatctgt tttaaaagac acaaaaacga
    53161 aaggacaacc tatgtcaaca gttaaacgct acgatgaaga attcaaacaa tcccttgtca
    53221 acctttatca aactggaaaa actcagtctg aactctgtaa agactatggg gtatccgctt
    53281 ctgcacttgc aaaatggatc aaacagtatt ctcaagtcaa actcgaagat aattctgtac
    53341 ttactgccaa gcaaatacaa gagctacaaa aacgtaatgc gcagcttgaa gaggagaacc
    53401 ttatcctaaa aaaagcaagt gccatattca tgcaaaactt aaagtaagac tcctcgctgt
    53461 ctatcggtta cgctttgaac acgccacaac aaccttatgt cgtgttttac gtgtcaatcg
    53521 ctccacttac tataaatttc taaaacataa gccctcaaaa agagaattgg ataatcaaat
    53581 ttatagaaaa caaatacttg agatttatac caaagcaaac aaaagacttg gtgtgaagtc
    53641 tatcaaggtc attcttcaaa gagactacga cacaaaaatc tctgaaggaa gaatttaccg
    53701 tctaatgaag aatatggcgc tccctaaaat ggctaccgtt aagccaaaaa cagctcttaa
    53761 aaggactcaa aaaacgtatc ctcaaaactt actcaaccag aaattttatc ctgacaaacc
    53821 taatcaagta tggtctactg acttcaccta tatttctatt ggatataaga aatatgtcta
    53881 tctctacgca atacttcatc tctattctag aaaatgtatt gcttggaaac tgaatcatcg
    53941 tatggatgca aagttagcat gtgacactct agaattagct cttaataaaa gaaagattga
    54001 aggaacactt ctctttcatt ccgaccaagg gtcacaattt aaggccaggg aattgagaaa
    54061 aataattgat gacaacacta tcatgcattc tttttctaaa cctggatatc cttatgataa
    54121 tgccgtaact gaagcatttt tcaagtattt aaagcataga caaatcaacc gaaaaaagta
    54181 tcaaaatatc aaacaggttc aattagactg ctttgaatac attgagaatt tttataacaa
    54241 ttacaaccca catacggcta atctaggact aacccctaat cagaaagaag aaaattagtt
    54301 taacgtaata aaataacacg gttttctgtc tacttatttg acattagtcc aaaatacatc
    54361 ctaatggtgt cgcttttttt atttcactag acattcgttc tagtttagga tataagaagg
    54421 tctcaaattt ttttcaggat gtttattcca aacatccaat cacctttcta tataactgtt
    54481 catttagtgg tatagacaaa cagaaatact ccgtttctag tttcatagaa gacggagtat
    54541 tttttagtag agacgtctgg attgatagat agttggtata tagctcatcc ctactaggct
    54601 ttcattatag actatggtgg gtttcgttga caacaatatt tgattattat tctaaatgac
    54661 agtatacatc aactatcaag tatgctttta attttatttt ttaaagctac agatgaaaat
    54721 ctgtattcca
//
LOCUS       DAUNLR010000005        49665 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUNLR010000005 DAUNLR010000000
VERSION     DAUNLR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49665
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.005"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            97..1452
                     /gene="rocA"
                     /locus_tag="VLL59_000310"
     CDS             97..1452
                     /gene="rocA"
                     /locus_tag="VLL59_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HER6508468.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLEVVDFTKLLSFLLDNAIEMSLEIKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQDDSQSVFAIPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(1553..4258)
                     /locus_tag="VLL59_000311"
     CDS             complement(1553..4258)
                     /locus_tag="VLL59_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HER6508469.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTNP
                     NFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDKWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDDSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKTYHFGQRFPKEVYQEAQEYLARLSQ
                     SFQIIDTSGQVRPEAEILGTSIAFDYDLSKRTFREPYFAIKVRLRLPITLPAMSWKTL
                     ALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSEVSYQDLLQFED
                     CGDIGNEYISRQPNHDQPFYADQGTTKLKIISNTAQVAELEIQQTFAIPVSADKLLQA
                     EMEAVIDITERQSGRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(4273..5559)
                     /locus_tag="VLL59_000312"
     CDS             complement(4273..5559)
                     /locus_tag="VLL59_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HER6508470.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANEKGHQTDHTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNESVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            5692..6732
                     /locus_tag="VLL59_000313"
     CDS             5692..6732
                     /locus_tag="VLL59_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6508471.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAKKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLFQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            6783..8477
                     /locus_tag="VLL59_000314"
     CDS             6783..8477
                     /locus_tag="VLL59_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HER6508472.1"
                     /translation="MTIYHTLKDYQEVMTRGDYLVFDTPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFPMRGIIEGFYGTPWTREERIDCLRFIGNKRM
                     NTYMYAPKDDDYQRKQWRDLYPENWVTYFKELLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQSDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKNVSTLSAWVDELVELVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            8502..9944
                     /locus_tag="VLL59_000315"
     CDS             8502..9944
                     /locus_tag="VLL59_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HER6508473.1"
                     /translation="MLAFPKDFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPTLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAELSDGR
                     IGTILNLTPAYPASQSEADTAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDRVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDAYLMPGRRMN
                     VDKGWEIYPEAVYDIAVKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIRF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(10555..11433)
                     /locus_tag="VLL59_000316"
     CDS             complement(10555..11433)
                     /locus_tag="VLL59_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HER6508474.1"
                     /translation="MSLLCLDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIKEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVIGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALTEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            11629..12579
                     /locus_tag="VLL59_000317"
     CDS             11629..12579
                     /locus_tag="VLL59_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HER6508475.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            12589..13515
                     /locus_tag="VLL59_000318"
     CDS             12589..13515
                     /locus_tag="VLL59_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HER6508476.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            13596..15041
                     /locus_tag="VLL59_000319"
     CDS             13596..15041
                     /locus_tag="VLL59_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HER6508477.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            15347..15952
                     /locus_tag="VLL59_000320"
     CDS             15347..15952
                     /locus_tag="VLL59_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HER6508478.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLVI
                     TLVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            15942..17666
                     /locus_tag="VLL59_000321"
     CDS             15942..17666
                     /locus_tag="VLL59_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6508479.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMERRLQEHQTTCNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            17666..19150
                     /locus_tag="VLL59_000322"
     CDS             17666..19150
                     /locus_tag="VLL59_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6508480.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQHPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDCILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            19080..22586
                     /locus_tag="VLL59_000323"
     CDS             19080..22586
                     /locus_tag="VLL59_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HER6508481.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWITAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYADGKDYDRLHEEHSDWLLYGSET
                     VSAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLQVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKVSQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVSTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            22724..23602
                     /locus_tag="VLL59_000324"
     CDS             22724..23602
                     /locus_tag="VLL59_000324"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HER6508482.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            23837..24592
                     /locus_tag="VLL59_000325"
     CDS             23837..24592
                     /locus_tag="VLL59_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HER6508483.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            24645..24983
                     /locus_tag="VLL59_000326"
     CDS             24645..24983
                     /locus_tag="VLL59_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HER6508484.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            24985..25290
                     /locus_tag="VLL59_000327"
     CDS             24985..25290
                     /locus_tag="VLL59_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HER6508485.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(25726..26799)
                     /locus_tag="VLL59_000328"
     CDS             complement(25726..26799)
                     /locus_tag="VLL59_000328"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HER6508486.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQTKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKSLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLEHLIYQS
                     ISNKKQIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(26855..27607)
                     /locus_tag="VLL59_000329"
     CDS             complement(26855..27607)
                     /locus_tag="VLL59_000329"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HER6508487.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(27849..27919)
                     /locus_tag="VLL59_000330"
     tRNA            complement(27849..27919)
                     /locus_tag="VLL59_000330"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27885..27887),aa:Thr,seq:ggt)
     gene            28086..28340
                     /locus_tag="VLL59_000331"
     CDS             28086..28340
                     /locus_tag="VLL59_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HER6508488.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            28358..28753
                     /locus_tag="VLL59_000332"
     CDS             28358..28753
                     /locus_tag="VLL59_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HER6508489.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            29038..29357
                     /locus_tag="VLL59_000333"
                     /pseudo
     CDS             29038..29357
                     /locus_tag="VLL59_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264372.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            29354..29917
                     /locus_tag="VLL59_000334"
     CDS             29354..29917
                     /locus_tag="VLL59_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HER6508490.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTQLTAAETAQLIIQKMTHIKEN"
     gene            29919..32567
                     /locus_tag="VLL59_000335"
     CDS             29919..32567
                     /locus_tag="VLL59_000335"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HER6508491.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKLITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            32721..35129
                     /locus_tag="VLL59_000336"
     CDS             32721..35129
                     /locus_tag="VLL59_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HER6508492.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIALCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEERQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVSYGEAEKKLAYLEELGVSHFLS
                     AKDYQTIKSLLKELQPFTVNVRENDPLLDATKSFLNGQVLVLTSEYYDTERGVKYDSA
                     NFYF"
     gene            35262..35990
                     /gene="cas5c"
                     /locus_tag="VLL59_000337"
     CDS             35262..35990
                     /gene="cas5c"
                     /locus_tag="VLL59_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HER6508493.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGFVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            35990..37885
                     /gene="cas8c"
                     /locus_tag="VLL59_000338"
     CDS             35990..37885
                     /gene="cas8c"
                     /locus_tag="VLL59_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HER6508494.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QTQYDSFHKQLNNWIDYCEEGDVKKFLTFVQQFILKPEFLTLILDSLIGPDYQHNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEAKRENLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            37890..38738
                     /gene="cas7c"
                     /locus_tag="VLL59_000339"
     CDS             37890..38738
                     /gene="cas7c"
                     /locus_tag="VLL59_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HER6508495.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKADALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGHSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYHQSMEEKSTYDAYQIHLNQEKLAKYEAKGLTV
                     EILEGL"
     gene            38740..39414
                     /gene="cas4"
                     /locus_tag="VLL59_000340"
     CDS             38740..39414
                     /gene="cas4"
                     /locus_tag="VLL59_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HER6508496.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQI
                     LHTKADNPYIKEKRKDLLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHDVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            39411..40436
                     /gene="cas1c"
                     /locus_tag="VLL59_000341"
                     /pseudo
     CDS             39411..40436
                     /gene="cas1c"
                     /locus_tag="VLL59_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
     gene            40447..40740
                     /gene="cas2"
                     /locus_tag="VLL59_000342"
     CDS             40447..40740
                     /gene="cas2"
                     /locus_tag="VLL59_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HER6508497.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   40889..41124
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=40889..40920
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaat"
     gene            41280..41990
                     /gene="ccdA2"
                     /locus_tag="VLL59_000343"
     CDS             41280..41990
                     /gene="ccdA2"
                     /locus_tag="VLL59_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HER6508498.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            42003..42626
                     /locus_tag="VLL59_000344"
     CDS             42003..42626
                     /locus_tag="VLL59_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HER6508499.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            42669..43775
                     /gene="msrB"
                     /locus_tag="VLL59_000345"
     CDS             42669..43775
                     /gene="msrB"
                     /locus_tag="VLL59_000345"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HER6508500.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            43863..44603
                     /locus_tag="VLL59_000346"
     CDS             43863..44603
                     /locus_tag="VLL59_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HER6508501.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQKLVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            44600..46333
                     /locus_tag="VLL59_000347"
     CDS             44600..46333
                     /locus_tag="VLL59_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6508502.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITMLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFSFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAIADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMH
                     ELMADDTQENE"
     gene            46406..47485
                     /locus_tag="VLL59_000348"
     CDS             46406..47485
                     /locus_tag="VLL59_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HER6508503.1"
                     /translation="MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVEGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYVCQVLETNIPNEGYRKNPNIDKLMRLRKRQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            47499..48215
                     /locus_tag="VLL59_000349"
     CDS             47499..48215
                     /locus_tag="VLL59_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HER6508504.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(48381..48854)
                     /locus_tag="VLL59_000350"
     CDS             complement(48381..48854)
                     /locus_tag="VLL59_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HER6508505.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            48996..>49665
                     /locus_tag="VLL59_000351"
     CDS             48996..>49665
                     /locus_tag="VLL59_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HER6508506.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQ"
BASE COUNT        14899 a         9213 c        10813 g        14740 t
ORIGIN      
        1 ttaaaatgaa aaagctcagt ttatctatta cggagttcga aatgaaaaga aaatcgagat
       61 gtgataatat attttgaacg agaaggagaa ggataaatgt tagaagattt tcttcaattt
      121 ttaggattta tatttttaga tattattgaa attatgttaa cgttaaagct ttttagcttt
      181 gtaagtgcaa ttccgcttcg cctgaaaaat attttttatt tatcacttag tatggttttg
      241 tttcaagtag ttttttgggc tttctttcca gaccatttca ttcttgatgt tgtgatgttg
      301 gctcagtttc ttttctttgc gcttatagcc ctatactatg gtaaatcaat aaaagctaag
      361 tttttaatgt tttatgcctt ttttccacta gtgtctatta gtttggttaa gcgatttatt
      421 gtattttttg ttatgccatt gtttggtatg ccttattcag ttgttaaaca taatacacta
      481 ctgatttaca gcattacttg ttttagtatt tttttgattt atcgctgcat tcaagttttt
      541 catttcgatt tttcaacctg gcgccaatat tttcaatcac atagagctag taaactatta
      601 gtgtttacta actcttcgat ggctctatat tacttgtgtg tccaagggat agatgtgatg
      661 tcgccttctt tatcaggact tgctacaacg actgctcgtt caatcatagt gctcttttat
      721 ttcattttgt ttcttacttt attaattcat ttagagcgtt atgtaaaaca aaactctatt
      781 gaggcaattg tgcaacaaaa agaatatcgt gagctgatta attatagtca gcaccttgga
      841 ttgctgtatc aagatattca agagcttagg cagctattaa ctaccgtgtc cagtcgtctt
      901 aagattggaa tcgaacaaaa tgatatctct attgtgagac ttacttatga aggtatcttg
      961 aatgctgaaa agaataatgc taaagatgac agacttgatt taacttgttt agataaatta
     1021 caagttgaag caatcagaca tattgtttta gctaaattaa ttgaggcaaa aaataagaag
     1081 cttaaggttg aggtatcgat ccctaattgt attgcaacgt tttttctaga agtagtagat
     1141 ttcactaagc tattgtcatt tttgttagat aatgctatag aaatgagttt ggagataaag
     1201 caaccttgct tatcaatagc atttctggat caaaaccata aacttgtcat agtcattcaa
     1261 agcagtacta aacaaggaca agatgatagt caaagcgtgt ttgctatacc ggctttgaaa
     1321 aaaagagatg actggcaatt tgacttaagg aatgtcacga ccattttaaa tcgttatgac
     1381 tatctcacaa ttagctcgca gattcatgat ggcattttaa cccagttaat agaaatagct
     1441 aagcctgact gatgttaaag gtatgaataa tcactcaaaa tcaacttaag agtctgagac
     1501 aatagtccca gactcttttt gaatatgtta atctattact aatgataata gtttattgtt
     1561 tcttccaagc tagagttaaa atttccgctt tgccaagttg gctgggtgtg ctttgcttgc
     1621 tgtctttttc taacaaatta gtgaccttgg cattgtagtt tggcaggctt aggctaaagt
     1681 cacaagtttt atcgtttgag agattatagc tgcgcgtgat aagggcattg tctgctaagc
     1741 gacgtttgaa ggctgtgagg gcaacttggt cgtttgtacc cgtcaaatag ctatattctg
     1801 cggctaatgt tccctcgtgt tggtttgttt gtgtggtaat aacagggact tggccttctt
     1861 gagctcgcca gtagctggca aattgtgttt gcttagtgat gctttcaaaa ctataagaaa
     1921 ggctgtgctt gccgaggcat tgggcttcag gtgttgggaa gtaaccccag tcgcccattt
     1981 cgccaacaga acgtaagaga gtgatggcaa tggtgttggt atctggtaag atctcatatt
     2041 cgttgaggcc atagttacca atagtgactc cattttcacc atcaaagaga ctcacaaagc
     2101 attcttggtg ctgtgggtta cttggattct tccaaaaggt ggcatctgga tgatttggac
     2161 gtttgacagt ttcaaaaata ctgtcagcta gatgatggtc tgttttaagg tgcgttggga
     2221 ataggacgcg caagcgatga ttagtcattt ggttatcaaa acgtgtggtg aattggaggc
     2281 gaggattgtt tttctccatg cggataaggg ttgttaaggt tagctcagcc ttttcttgtg
     2341 aacgtcctga ttggcgttct gtgatgtcaa tgacagcctc catttcagcc tgtaagagct
     2401 tatctgcgga gacaggaatg gcaaaggttt gctggatttc aagttcagca acttgagcgg
     2461 tgttgctaat gatcttaagc ttggtggtcc cttggtctgc atagaaaggt tggtcatgat
     2521 ttggttggcg ggaaatgtat tcatttccaa tatcgccaca atcttcaaac tgtaggagat
     2581 cttgatagct cacctctgac tgtttatcgg tgatggttag acgaccatcg gtttgtatca
     2641 taacttttag aaactcattt tcaaggcact gattactatc gtcgtagagt gggaccgttg
     2701 ctgaaggagc tgtctcgttt cctagttgta atgctaaggt tttccaagac atggctggga
     2761 gagttattgg tagccgtaat ctcactttta tggcgaaata aggttctcgg aaggttctct
     2821 tggacaaatc gtagtcaaaa gcgatgcttg tgcctaaaat ttctgcttcg ggtctcactt
     2881 gtccactagt gtcaataatt tggaaagatt gggagagtct tgccaaatat tcttgagctt
     2941 cttggtaaac ctctttagga aagcgttgac caaaatgata tgttttccag gtcaggctga
     3001 gctcagcaac acttgttttg gaatggccgc tggtattaaa taagacgaag ggttggctat
     3061 ccattggaaa atccctggta tcaatggcgt cagcaatttg cttagcagct tcttttgcta
     3121 aatagtgtcc gacttcatag gctttttcaa agcgcgtcat catttcccga tgaacgctat
     3181 caacactaca accacagata gaatcatgag ggtgattttg catgagggtt ttccaagcgt
     3241 aacgcagttg gtcgtgaggg taggtacttg ttacctcata agccattgct gctaagggtt
     3301 cggtgatgtt ttcgagttgg cgagagactc tggtattagc ctgtttgagg taaatacgag
     3361 cagaagccgt gttagctagg gtataccagc catcggtttc ttgactggta atctctcctt
     3421 ggacggttga aaggttctct ggtaaatcat ctgcgagatc agccaagtaa tcttcaaagc
     3481 aggaatgcac aaattcgtag tcaggataga gttggttggc taaggcgatt gccttggtga
     3541 catcaagttg tacgggttga tgatcacacc cgttcatcat cagaaggtgc ttggttgagg
     3601 cgaagcgttc ggcgtcagca agttttttat cccaaaaaag acgcgcctca gcttctgttg
     3661 tcgggatctc attgccattg ctgtaccagt tggcgaagag gagtccaaga atacgactgt
     3721 catctggtcc ttgccaactg atttcagaga attgggagct gtatttttca ctggtatcta
     3781 cttgattgtt aaatccagtt ggacgaatgc cacgaccaaa ggcagcagct tgtaggccgg
     3841 cttttaacat cagctgtggt gtttgtccca tatttccaaa ggtatctgga aaataaccaa
     3901 gtggcacact agcgccccat ttgtcacaat cctccttgcc aatgagcata ttgcgcacat
     3961 tggactcgct gctggtcaaa aaatcgtcct gtaagatata gaaaggtccg atacggagtt
     4021 ttcccgaagc aatggcttgt ctaatctcag gttctcgttc ggggcgtact tttaaataat
     4081 catctaggat aatggtttga ccatccaaat gaaaactatg aaaattagga tttgtttgaa
     4141 aaacttctaa caggtcatct attaagttaa tcagacgcat gtggtgttgc tcgtaagcca
     4201 tgtaccactc gcgatcccag tgactgtgtg aaataatatg tacttttttg gttgccatag
     4261 tggcctcact ttctaaggag caatgctaaa gccaagatag tcaagaagta gttcacagaa
     4321 catcatgtta gcccaagaga accactcacg ggtgtattga taaggatcat tgacatcgaa
     4381 accctcgtgc attaagtggg taccagcatc tgttgccaca agcaaatcaa gcatctcttt
     4441 tttactgtct tggtcaagag cggtcaatcc ttgtaaggca agggcgatat gccagatata
     4501 attttctggt gtatgggaag aaccgatgcc tgctgctgca tttccctgat aataataagg
     4561 gttttcttgg ctgagaatgg tgcggcgcgt tgccaaatag atagggtcat ctttagcgca
     4621 aaaaccaagg taaggtgcag caaggaggct tggaatatta gcatcatcca tgatggaaaa
     4681 ctgtcccaga ccatccactt cataagcgta aatggtttct cccttgctgt tttgaacaag
     4741 ggcatggtct gcaatacccg attgaatagc ttctttcagc tgcttggcac gagtagctac
     4801 tgattcattg tgaaaaaggt tgttatataa atcttctaga taggaaagca caaccactgc
     4861 aaacatattt gaaggaatga ggtaaccata ttgacaagca tcatcacttg gtctaaagcc
     4921 tgaccaggtc attcctgttg gtgcgacagg acttcctttt ccagcatgtg ttaaggtatc
     4981 ttctttgcgc caagtatcgc gttcaaacaa gtaaggagac tgggcgtggt cttgctcaac
     5041 tgtccatagg tcaagaatga gttctacccc acgatgaaaa tcgtcattaa actgatcggt
     5101 gcttcctgtt tcacgataga gcagataagc cagttgaata gggtagcaaa gggaatcaat
     5161 ctcatatttg cgttcccaaa tccaagggtt catttgggta tgatctgttt ggtgtccttt
     5221 ttcgttagct tcttcgttga aggcattggc atagggatcg atacaaatgt agcggaattg
     5281 gcgtttgacc agaccggcaa taatctttct aatttcttca tcttccttgg cgaggaagag
     5341 gtaaggtttc atttgcgcag tggaatcacg taaccacatg gcaggaatat cgccagttaa
     5401 aagaaagcta gtaccatctt cgtaggtttt tagggttgtc tctaaggtat tggtaaagct
     5461 ggttttgaaa ttaagagccc aatcagggtg ttggtctcca caaaggcttt ccaccttggc
     5521 cataaattgg ctgacgctag ttgggattgg tcgtgtcatg tcatatcctc caaaatgata
     5581 tatcatttat cttcggtttc attataaatg ataagttaaa ctttgtctat aagtttttga
     5641 aaaggtttac aactcttttt tgacatgtta tactgataac aggagtaaag aatgacaaaa
     5701 ttattataca aaaagatata tcatttcatt aaagagcaga tagcatcagg tcgtttgcaa
     5761 attggtgacc gcctacctac tgaaaaagaa ttgtcagaac agttctcggt tagccgtatt
     5821 acttctaagc gagcgcttgt agaactggag caagaaggct tgattacgag aagtcgtggg
     5881 aaaggaagct tcgtagctaa aaagcaagtg acgtcccctg aagcgaataa ggatttattg
     5941 ttgattcttc cttttgcttc tgattatgaa ttgggagatt atgctaaggg aattatgacc
     6001 tccattgctg aaacaggtta ccgtctcatg gtccaattgg ccagtacagt aaggttagac
     6061 accctgtccg attatgctgg gattatttat tatcctgaag atgtcaatca cagtattgat
     6121 ttcttgtttt actgcgacca tcatcacatt cctctagtct tgttggataa atctctggat
     6181 ctttttcagt ttccgtctgt tgtagcggat aataaaggcg gtgcctgtca attgactcag
     6241 cacttgattg agcaaggctg tgaccagatt agttttgtgg caacaggctc ttttggagaa
     6301 gtatcatccg ttagagaccg ttatttgggt tacttagcgg caatggcaga atcgtctcta
     6361 aaatcccatt attttcctaa gacagagact gaaacaacag atgcttattt ggaccgtttg
     6421 gtgaaaacct tatcggaaac gacagccact aaaagggggc ttgtcgtgga aaacgattgg
     6481 ttggctattc agctgattca aaaaatcaca caggtaggct tatctattcc tgatcaagtc
     6541 gctattgtag gctttgataa tagtcaagcc tcccgtttgt tgagtcccaa attaagcaca
     6601 gcagctcaag atttttacca aatggggcaa gaagcagcta aagtcttgtt ccagattatt
     6661 catgagccag accaagcagt ggtgtcttgc cagttacctg ttcaagtatt tatcagagaa
     6721 agtagtcact aaaaaagacg ttactatcat gagctggtta gctcaggtaa aggagaccag
     6781 aaatgaccat ttatcacacc ttaaaggatt atcaagaagt catgacaaga ggagactatc
     6841 ttgtctttga cacgccattg acttgccgat ttattggccg ttttttccgc tttgaaaatc
     6901 aaaaagccct gctggcagaa ttggcaacgt caaagtattt tcagtggatt gaagaaggcc
     6961 aagcagaggt gacgatgaaa cactttttta accgtcagct ggctaaggat gcctttaccc
     7021 tgaaggtttc agaagataag gaaatcatta ttgaaagcca aaaccttaga ggttttcgtt
     7081 acgcccaaga agctttgctt aaagtcatga ccttcaaagg ggataaactt tatttgccca
     7141 ttgtttctgt caagcacagc ccgtcatttc ctatgcgggg gataattgaa ggcttttatg
     7201 gaacaccgtg gacacgagag gaacgaatcg attgcctgcg ttttattgga aataaaagga
     7261 tgaatactta catgtatgct ccgaaagatg atgattacca acgcaaacaa tggcgagacc
     7321 tctatcctga gaattgggtg acttatttca aagagctact tgcagtagcc aaggaagaag
     7381 ggattgattt ttggtatatg attagtccgg gacttgattt tgattatacc aaggaagctg
     7441 actatcagtt gctctatcaa aaattgcaac aacttctagc gttaggtgtt tgtcattttg
     7501 ggcttttgct ggatgatatt gactaccaaa ttgtagatgc tgttgagaga cgattcaaaa
     7561 agactgccta tgcccaggcc cacttggcaa ctgaggttca tcacttttta aaccaacaac
     7621 atgcggcgcc agaattggtg atctgtccga cagaatacga taatcaccat gattctatct
     7681 atttgcaaga gctgtcagaa aggattccta aagaagtcgc ctttttctgg acaggcccaa
     7741 gcacgctagc gagtcaaata tcgcaagcag atattgaaac tatggcagca gtatatcaac
     7801 ggcctatcat tatttgggac aatattcctg ttaatgatta tcaaaaagat ccagaacgtc
     7861 tctttttaac cccttttgcc aatcgctcgc catttttatg ccaatcagac tatcaggtca
     7921 aggggattgt ttctaaccct atgattagtt gggaattatc taagctgacc ttgacagata
     7981 tgagccatta tctgtgggat gctaaccgtt atcagcctag tcattcttgg ctagaaacct
     8041 taacagacta tacagaagat actgaattag ccctagcttt acaggcattt gcttggcata
     8101 atggcaatcg tcatctgcac agggaccttc cttttgaagt ggaagaagct ctcctggcta
     8161 agaatgtatc aacgttatca gcttgggtag atgaattggt agaacttgtc aataccttga
     8221 gaaagctaga taagccagcg tttcaacaag ctattgctcc ttggtttgaa cgtgtggcca
     8281 aagaccaaga tttttggcag gctatgttaa atcaggagcc tcagttggaa acactctatg
     8341 ctgacttaca agaagataaa caccgcattg gaagtgacat tccaagtcgt tactatcgca
     8401 tctactatca acagcaagat aaactaacag ctaatcaagg tcaagttacc caagcaagac
     8461 ctgaagatta tgcttagtca tacgagctag aaaggaatga tatgttagca tttccaaaag
     8521 atttttggtg gggaggagcc acttcaggcc ctcaaagtga ggggcgtttt gctaagcagc
     8581 accgcaatct ctttgattat tggtatgaag aggagcctac cttgttttac gattacgtgg
     8641 gacctgatac ggcttcggat gcctatcatc agattgaatc tgatttgacc ttgttagctt
     8701 cactaggtca caattcctac cgcacctcca ttcagtggac acgtttgatt gatgattttg
     8761 agcaagcgac gattaatcct gatggccttg cttattataa tcgagtgatt gatgcttgct
     8821 tggccaatgg tattcgtcct gttattaatt tgcatcattt tgacctgcca attgccctct
     8881 atcaagccta tggtggctgg gaatcaaagc atgtcgtgga cttatttgtc gcctttagca
     8941 aggtttgttt tgagcagttt ggtgatcggg ttaaggattg gtttgtccac aatgaaccta
     9001 tggtcgttgt ggaaggctct tatttaatgc aatttcatta ccctgctatc gtggatggga
     9061 aaaaagcagt ccaggtcgcc tataatctag ccctagccac agccaaagtt attcaagctt
     9121 acaggcgagg tccagcagaa cttagtgatg ggcgtattgg aaccattctc aatctgacgc
     9181 cagcctaccc agctagtcaa tcagaagcgg atacggctgc tgcgcatttt gcagaacttt
     9241 ggaacaatga cttgtttatg gaagctgctg ttcatgggaa attcccagaa gaattggttg
     9301 cggtattgaa aaaagatagg gttttgtggc agtcaacgcc agaagaattg gctcttattg
     9361 ctgagaatag agtggattat ttgggattga atttttacca ccctaagcgc gtgaaggctc
     9421 cggatgtcat tccagtgatt agcccatctt ggagtcctga atggtattat gacgcctacc
     9481 tgatgcctgg ccgccgcatg aacgtggata aggggtggga aatctatcct gaggctgtct
     9541 atgatattgc tgtcaagatg cgagaccatt acgacaatat cccttggttc ttatctgaaa
     9601 atggtgtagg gatttcagga gaagaccgtt accgtgatga aactggtcag attcaagatg
     9661 attatcgcat ccgatttttg aaagaacatt taacctacct ccacaaagga atagaagcag
     9721 gctcgaattg ttttggatac catgtatgga cgccaattga tggctggtct tggctcaatg
     9781 cctataaaaa ccgctatggc cttgtggaaa ataatatcca tacccaagtg cgacgaccta
     9841 aagcttcagc ttattggttt aaaaaagtag ctactcataa ccgcttgatt tcattagaag
     9901 taatggagga gtttggaggc tctgcttctc acctcagtga ttgaacgtgt gaacgtctcc
     9961 tttgagacaa gtgaataatg atgttaccaa tgattaaaca agggcctttt tcctcatgtt
    10021 aagaggatcg aggctcttgt atttctttgg aaggtgttgg tatttgccga actagatata
    10081 agcgctctgt ctggtttggc atcatctatc catcttgggt aatttggctc ttcaattctt
    10141 tagagtatct tggctaagga tgcttgtttt tcatcttggt attttaggat tttctttcat
    10201 atttttggac cagataaaag cccctcatgg tttctagtga ctgtttgtta tgtcactgtc
    10261 cacgataagg ggactatatg agtgagttat taagtgaggc tttgcttatt ggcgataact
    10321 agcatagctt ctaatagctc gagtattaac tgatgaccaa tgcctttgac agaagcgtca
    10381 gcaacaacga catcaacaaa gggaccaggc atcaggctgc gttcatcagc agagagtcat
    10441 ttaggcagaa agccagtatc gttgtagcta atcagcaatc cttttaggat gtctttgtag
    10501 atgtcagagg cgattaggga caatagggga taagagggat ttagcggtcc atggttaggc
    10561 ctccttgtgt tcttggtaaa aatcaatggc agctccaaga agattggctt cgtttttaaa
    10621 gtgacaaata gctaattggg gtctaaggtc ggagatttcg acggcttggt agagtttgtc
    10681 tagttcagct tcaatcgctg acagtagaaa gtcagcttgg gaaacaccac ccccgattaa
    10741 aatcagttga ggatcaaagg cgtgttgaat gttaaaaata ccgatggcta aactttggag
    10801 aaagacctgc ctttctttga gtgctagggg atctccttgt tctgtgaggg caaggacagc
    10861 tttgccagta taatcttttc cgttattgac gattgcacta tagcgcttgg ccatattcac
    10921 aacagtgcct aattgactaa aggtttggta gcggtcgttc atgatcatga aaccaaattc
    10981 gcccccaaat aagtgggcac catggtaaat cttgccatca atgaccaagc ttcctccaac
    11041 tccagtacca ataacgagca tggctaggct actagcgcct tttcctgccc ctaaggtagc
    11101 ttcagctaag gcggcacaat tggcatcatt ttcgatagaa atagggtaat gtagccgttc
    11161 ttctaaggcc tcttttattt taaaatggtg aatgtaggga atagcgctgg cgccttcgat
    11221 aacccccttt tctttattga ctgccccagg tgaactgatg gcaatacctg agaaatggta
    11281 agcagagtaa cgagcaactt cttggtcgag taattggtaa aacttttcca gactagaggg
    11341 agtgggaaag ctgctttgct ggcttaattg gccattgtga cagagggcaa atttaaggga
    11401 agtgcctcct atatcaagac ataacaagct catgaggtgt tctcctttat tatagtagaa
    11461 tagacgatca tgtctcatct tagtatgaca gatttaagca acaatgaaaa ggctttctaa
    11521 gtgattctat actttgtgtt atcataccta taatttgttg ctttcaaata atgaaagcgc
    11581 ttgatatact gtaactataa cgtgattaac acaaagggag gttgggaaat gacaagacag
    11641 accaacaaaa agacatcctt ttggaaaaat gtgattaaat accgggcctt attattaatg
    11701 gtattaccag gtttcatctg gttcatcttt ttcttttata ttccagtttt agccaatgtg
    11761 gttgctttta aagattttca ttattcagca gggggcttta tggaaagttt gaaggagagc
    11821 ccttgggttg gtttggctaa cttcaaatac ctctttgctt ctaaagatgc ttggttgatt
    11881 accagaaata ccatcgctta caatgttatt ttcttactct ttaatgtttt ctttgcgatt
    11941 gcttttgcca ttatcatgag tgagttacga aataagcgaa cggttaaggt ctatcacacc
    12001 atgtccttat tgccttattt cttatcatgg gtggttattg aatactttgt ttctgccttt
    12061 ttaaatacgg ataaaggttt cattaatcag ctcttgactg gaagtggagc agatccaatc
    12121 aagtggtatt ccaatcccac ttggtggccc ttgattttac tctttatgag tgtctggaaa
    12181 gggctaggct acaatagcat tatctactat gcttcagtca aagggatttc tgatacttat
    12241 tatgaagctg ctatggtgga tggtgcaagc aaatggcaac aaattaggaa catcaccatt
    12301 ccacaattat tgccaatgat gtctatccta ttgatcatta atattggtaa tatctttaaa
    12361 tctgatttcg gacttttcta cgttattccc aaaaattcag gcccacttta tgacgtgacc
    12421 agtgtgttag atacctatgt ctacaatgcc ttgactgcta caggagatat tgggatggca
    12481 tcggcagcta gcctttatca gtcagtagtt gggaccagca tcttgttagt caccaatgcg
    12541 attgttcgtc gcatggaccc tgatgcagcc ttgttttagg aggaaaacat ggagaaaaag
    12601 aaaaaagtcg aaaaggttaa tgttagaacc tttgatcgaa aaaccaatgc tatctttaat
    12661 attctgattg gtctgtttgc catctcttgt atcattcctt ttatcttcgt gattattatt
    12721 tccttcactg atgaaagtta cttgattaat catgggtata gtttttttcc agatgtctgg
    12781 tcaactaagg cttaccagta tatttttcaa ggagccatgt cccatagaat catgaggtca
    12841 tttgggatat ccgtgtttat tacagtggtg ggaaccttta ttaacacgac catgacatca
    12901 acctatgctt atgcgatttc aagaccttat ttcccataca gacgcttttt cactgtttat
    12961 gcgcttatca ccatgctctt tgcaccaggg atggttgcta attacttggt ggtcagcaat
    13021 ctccttcatt tgaaggatac ggtttgggcc ttgattttac caatggctct gggcccattt
    13081 ggcatcttgg tcatgagaac gttctttaaa aagacagttc cagatagcat tattgagtcg
    13141 gctcgtatgg atggggctag tgaatggatg atttttatga aaattgttct ccctttggct
    13201 gttccaggga ttgctaccat cagtttattt tctgccttaa cttattggaa tgattggttt
    13261 aacgccttgc tttatgtgca aagtgaaaac ctctacccaa tgcagtactt actgatgaaa
    13321 attcagagca acctacaggc cttggcacaa aatgctggca tgagtgcaca aatggcagat
    13381 agcttagcat cgctgccaaa agaatcagtt cgtatggcta tcgtggttat tgcaaccttg
    13441 ccgattgcct tgacttaccc attcttccaa aagtactttg tcggtggttt gaccattggt
    13501 ggggtgaagg aataggactt aaggaactgg tcacaagacc agattttatc taatcattag
    13561 taacaaaaga aaacattttt taggaggctt cacttatgaa aaagtggcaa aaaatcgtgt
    13621 gtgtgactgg aactgtgctt gcagcgtcta gtttagcagc ctgcgaaagc aagtcagcat
    13681 caaaggatag tgatgtcaaa ttattgatgt accaagttgg tgacaaacct gataacttcg
    13741 atgaattgat gacaattgct aacaagcgca tcaaagaaaa aacaggtgca acggttgacc
    13801 ttcaatacat cggttggggg gactgggatg ataaaatgag taccatcatt gcctctggtg
    13861 aaaactacga cattgctttt gccaataatt atgtggtcaa tgcacaaaaa ggtgcttttg
    13921 ctgatttgac aacgttaatg ccaaaatacg ctaagaaaac gtataaaaac ttagacccag
    13981 cctatattaa aggaaatact attgacggta aactctatgc cttcccagta gatgccaacg
    14041 tttatgccca acagatgctt tctttcaata aagaactagt ggacaaatat ggccttgaca
    14101 tttcaaacat taagtcctat gcagatgctg aaaatgtctt gaaacaattc cacgaaaaag
    14161 aaccaaatac agcagctttt gctattggtc aagtctttag tatgtcaggt gactatgact
    14221 acccattaac caaaacccaa ccctttgctg tgaaaattga tgaaggcaag ccaaccatca
    14281 ttaatcagta tgaagatgag tcctttaaaa acaatctccg cttgatgcac aaatggtata
    14341 aagaaggttt gattccaaca gatgcagcga ccaatacaga aggttatccc cttgaaggaa
    14401 acacttggtt tatgcgtgaa gaaacccaag gtcctatgga ctatggcgat actatcttga
    14461 ccaatgctgc aggaaaagac atcgtgtctc gtccattgac taaaccgcta aaaaccacat
    14521 cacaagcaca aatggcaaac tttgtggtat caagcgtatc taaaaacaaa gaaaaagcag
    14581 ttgaagtcct ttctcttctt aatagcgatc ccgaattgtt aaatgggctt gtttatggtg
    14641 tcgaaggcaa agcttgggaa aaaattggcg acaagaaaat caaactgctc gatggctatc
    14701 aaccaaaaat gcacatgggt gcttggaata ctggtaacaa taaaatcctt tacactcaag
    14761 aatctgttac tgacgacatg attgctaaac gtgaccaatc aatcaaggat gctaaagaat
    14821 ctccaatcct tggtttcact gttgacacaa aagttatcaa aacggaattg tcaaatattt
    14881 caaatgtcat gaaccgatat aaagcaagta tcaatactgg tacagtggat cctgacgaag
    14941 cccttccaaa acttcttgca gacctcaaag gtgctggttg ggacaaggtg caaaaagaag
    15001 ttcaaaaaca attggacgac tttgtagcta aagacaagta aggcattcat tttcttgatt
    15061 ataagttgag ggctgggaaa tctcagctct tttcttctga tgagtggaaa aaacggatca
    15121 tcaaataagt ggaagttata aagggagaaa aattaatgga aatattgtta ctactcttag
    15181 taaagcggtt tccaaaagcc tataaagtgt gctatattag aagagtctaa actattaatc
    15241 agagtaaaac taataccagc atcttactgg gggtgctaaa actagtctcg tagctgctgg
    15301 tccctgaaac cgctataagt gttaacaaga aaaagaggac tatcatatga atggcattga
    15361 aaaaacctgc tttttaattt ggaaaatgat ccaattgacc ctcatttttc atctcttgtc
    15421 cttagctgga ctgattgtgt ttggggtggg gccagcctgg caaaccattg tcaccctatt
    15481 tttaaaaaca cctcaagaag aaaaccacta ttctttgaaa agggctgttc aactttggaa
    15541 atcttatttc aaagaagcta atctaagatt tggtcttttt gccctgactt tccttttttt
    15601 aacctttaat ttgcattggg cagtacagtt tccatccttg ttttggttta ccgtgtcttt
    15661 cttgattgta atagccatgg tttggctaac catgacctat ctttacatgg ttttttatgc
    15721 agtgagctat gagattaacc tttggaataa tatgaaatta gcctttatca gcgtcttttt
    15781 aagtttcaaa tcctttttac tcatgctgag tgttttgctg gtaattacct tagtgacttg
    15841 gcaatacaaa ggtctttatc tctttttaac cttcggagct ctagtctttt gcttggactt
    15901 tgtcactaag gctaatcgtc gactagtaga tggagtgatt gatgagtgtt aaaacattgg
    15961 gaaggtatgt gactaaccac tttaagcagg gttttttgat taatcgactg atgaaattat
    16021 atagcctgct aattgtaagt tttttcactt tagcagctat tggcttgagc agttattcta
    16081 ttagtagtac ttataaaagg gtggatgctg aggcgcagat gcgactggag gagactctag
    16141 gtagattgca gtcacaaaac gatattaccc tacgggtttt agaccagttg gttggccgtt
    16201 cagaagatta ccataatctc tatcaataca tgacgttaac cccaaaccaa tatttttcca
    16261 acgtttttga agactgggaa aaaggaaaag acacggtcct attttctgaa gaggtgaggc
    16321 gtctttttga cttgtaccct gatgtgactt ctatgaccct actgctagag gacagtagtg
    16381 cttatctgta cgccgatagg gtcattaaga cgggtcgttt gctttatagc aagcctgaaa
    16441 aagtaaccgg aaatgtttta gttcgctcta ttcgaaatcc agaatcagga gatgtgacag
    16501 gtcgtcttta cctgaccttt gacaaaccac cgactttggt agagacacag caggatcact
    16561 atttagctac ttttgctttt gattactatg gccgcaaact cttccatcaa ggaggtcgga
    16621 gatttcctca tttagaggct gaggttaaaa aggctatcaa ggcagatcgg gcagctgatc
    16681 ttagtaatct tagcaaggct tatcggatgc agtacaatcg ctcgggagac ctcttagctt
    16741 atgtggctgt cagaaaatcc tatttattag cggaagctgt caggacagtt tttgtgtatg
    16801 gccttgtttc tctactctta gcttggctgt tattgcagtt gctctttagg gttttccgaa
    16861 attatatcca gcaggtttct gaaattacgg atactgttga aatggttgca gcaggcgatt
    16921 tgtctttaac catcgacaac agccacatgg aattggaact gtatcatatc tcagaagcca
    16981 ttaatcagat gttggccagc attaaagctt atattgacga agtttatgtg ttagaggtag
    17041 agcaacgaga tgcccaaatg agagctctgc agtctcaaat caaccctcat tttttataca
    17101 acacgttaga gtatattcgg atgtacgccc ttagttgtca acaagaagaa ttagcagatg
    17161 tcatttatgc ctttgcgagt ctgcttcgca acaatattag ccaagataag atgaccacct
    17221 taaaagaaga actggctttt tgtgaaaagt acatttacct ttatcaaatg cggtatccag
    17281 atagcttcgc ttatcatgta aaaattgatg agagtattgc tgacttagcc attcctaaat
    17341 ttgtcattca acctctcgtt gaaaattatt ttgtgcatgg gattgattat agtcgccatg
    17401 acaatgcact aagcatcaag gctttagatg agacggatca tctcttgatt caggtgcttg
    17461 ataatggacg tggtattagt caagagcgcc tagcagatat ggaaagaagg cttcaagagc
    17521 accaaacaac atgcaatagc tctattggtt tgcaaaatgt ttacctccgt cttttccatc
    17581 attttcgaga cagggtttct tggtccatgg ctaaggagcc aaatggtggc tttatcattc
    17641 aaattaggat tagaaaggat gcttgatgta taaggtacta ttagttgacg atgaatacat
    17701 gattttacaa gggctcacca tgattattga ttggcaggca cttggatttg aagtggttca
    17761 aacagcaaga tcaggcaagg aagccttagc ctatttgact cagcacccag tcgatgtcat
    17821 gatttcagat gttaccatgc ctggaatgac aggactggat ttaatagaag cagctaaaac
    17881 ctatcatcct cagctacaaa ccttgatttt atctggttat caagaattct cctatgtgca
    17941 aaaggctatg gaattagaaa ccaaggggta tttgctaaaa cctgtggata aggcagaatt
    18001 acaggctaaa atgaaacaat ttaaagactg gttggatgcc cagcaggcag aatcaatccg
    18061 gcaagaagcc tatcatgaca gccttttgac cctttggctt acagatgaat tgagtgagaa
    18121 agaatttcag cagttaagtc aaggcttgcc agcggctgct ttaactggtt ttacagtgct
    18181 gtatttggac tgtcaagagt ggcaagcagc catcgatgct tattttgaac gagaaggtca
    18241 gcctttttat ctcaaaaaag aagaagataa gaaggtttat ctggctgtcc tacttggtaa
    18301 aactgatcaa gccaaggcgt ttacctatga tctacaaaag cgattctcaa gaaacatgca
    18361 tcaacttatt ttgggagaaa cagttgatga ctgggaaaat gtttatgaaa gctacaatca
    18421 ggtgcttaag agcctctttt acaattgtga agtgtcacca attagagcaa aagataagtc
    18481 caaaattgaa ctaccagagt cccgtttgca gttctttgct tttaacaagg cgttgatgat
    18541 tggggacgaa cctacaatct tgtctaaatt agaagctatt tttgacgaga tgaagacctt
    18601 gaacttttca ccagaggatg tgaagcatgt ttcgttcttg ttgttttctg acatttaccg
    18661 tcaatttccc attttagata aaatgactta tctgtccatg gtaaaaacta ttcatgacag
    18721 ccaatccatt gattgcattt tgagggaact aaaaaaagtg ttggatgtca ccaatcagaa
    18781 caattcccct gaaaaacgct attcagattt agttagtgaa accattgatt gcattcgcaa
    18841 ggaataccat caagaattaa ctcttaaagc tatcgctgat aggttacatg tcaatggggt
    18901 ttatttaggg caatgcttta aaaatgaaac cgagcgtagt tttacccagt acttaaatca
    18961 tgttaggatt caaaaagcgc aacagttatt gctttacacc aaccaatcca tcaatgaaat
    19021 tgcttatgaa acaggttaca ataccaatca ttattttatc aagatgttta aaaagttgaa
    19081 tggtttatcg ccaaaagagt tcagagatcg ttacaaggac aattaccaag ccatcaaggg
    19141 cgaccagtaa cgtcaaacag gagattgata tgacaccaga tagcaaggag cagacagtga
    19201 ctggctacca ataccactat attgatcaag aaggaagaaa gcagcccttt aatcaaggct
    19261 ggcgttttct tatggcagat gtggcgtgtg ctcaggaccc ttcttttgat gattcgaact
    19321 ggcaggtgat tcatttacca catgatttca gtcttacgca gccttacaca agaaatggtg
    19381 aagctgaaag tgcttataaa ttaggtggtg tcggttggta tcggcattat ctcgtgttag
    19441 atgaggtttt agctggttgt catgttgcca ttacttttga gggttcctat atggaaacgg
    19501 aaatttatgt taacgggcaa ttcattggca aacacttaaa tggctatcag gaatttactt
    19561 atgatatctc tgatgttgtg acttttggag ctgaaaatct tctggctgtc cgggttgaaa
    19621 acaaggttcc cagttctcgt tggtattcag gcagtggtct ttatcgtgaa gtgagtttgt
    19681 ctgttcttcc ccagcttcat tttgtggcag accaggtagc aatgaccttg gctgatactg
    19741 ctgtgcagga gaaagggcaa cagaaagttg atttacgctt tgccctcaat cagtctattc
    19801 agacttgcca ctaccaattg agcctctgtt tatgggaaca atcacattgc tcaaaagaca
    19861 agaaactcct ttatcaagaa acagaagtgc ctctagctga tttggctttc caaagacagt
    19921 atggtcttac actgtctttg gaagaactcc aattgtggtc accagataat cctcacctct
    19981 acgatttaga actcactctt tactatcaag gtcaggtcat tgattgcttt tgccttgaaa
    20041 ctggttttcg tcagctgact tttatggcca atcaggggct ttttgtgaat ggcagagctg
    20101 tcaaattaaa gggagtttgt ttgcatcatg accaaggagg cctaggagct tgtgcttacg
    20161 aagatgccct agccagacaa ttagtcctgt tgaaagacat gggggctaat accattcgta
    20221 gcacccataa cccaagtagt cccaaactta ggcaactagc caatcgtctc ggcttttttg
    20281 tgattgaaga agcctttgac acctggacct atgccaaaaa tggaaacgtt aatgactttt
    20341 caaactattt ccatcagact atcggaactg aaaatgcaaa ctatcttcaa agagtgaggt
    20401 cacctgaaac gagctgggcc cagtatagta ttgaggccat ggtctggtct gccaagaatg
    20461 acccgtcagt gttgatgtgg tcgattggta atgaattgat ggagggtttt tcagccgatg
    20521 tcagtcatta cccagagctg acaagacaaa tgtgccaatg gattactgct attgacacct
    20581 cacgtcccat tacctttggg gacaataaat taaaagaagc tgacttttgc tggcatgagg
    20641 aagtgtcgca aatggcaact cttcttagtc aattagacca tcctcaggga ctcattgggt
    20701 taaactatgc tgatggaaaa gactatgata ggcttcatga ggagcactct gattggctgt
    20761 tgtatggttc tgaaacagtc tcagccatta ccagcagggc ttattataaa gagacaaaaa
    20821 aagttcttga ctccggttat cacctaacct cttatgatca tgctaaggtt gattggggtg
    20881 ccttcgctag ccaggcttgg tatgatacca ttacccgtga ttttgttgct ggcgaatgcg
    20941 tttggacagg ctttgattat ttaggagaac ctaccccctg gaacaagatc gacagcggtg
    21001 ttgtaggcct ttggccttct cctaaaaatg cctactttgg cattttagac acggcaggct
    21061 ttccaaaaga tagctattat ttttaccaaa gtcagtgggc gcaggggcag accaccttgc
    21121 acctgttacc agtctggcag aaggaccagc tttgtttcga tgagcaggga ttggtggagg
    21181 ttgtggttta tagcaatgct gccagtgtgc aactgatgtt tgaagatgag cagggcaact
    21241 taacagatta tggaaggaag gcatttcata cttatagcac gccaacggga cacacttatc
    21301 agctttacca aggagctgac gctgctaaga atcctcacga gaacctttac ctgacttggc
    21361 gagtgcccta tcaaaaaggg ttgctaaggg cagtggccta cgacatttct ggtaaaagca
    21421 ttccaaaaac cagtggacgt tctcaggtta gaacctatgg ttcagtggca aagctatctt
    21481 ggaaagcctt tgaagcacct attgacgctc cttgggaatt gctttatctg gatttatcac
    21541 tcttggatag ccgaggtgaa ttggtcagcc atgctcaaga ttggttgcag gttcaagtag
    21601 aaggaccagc ccgtttgttg gctcttgata atgggaatcc gactgaccac accccttatc
    21661 aggagcctct gcgccaggca tatgggggaa aattattagc cattttagcc ctcactggag
    21721 aggcgggaca cattaaggtc acggcaaaag tctcgcagca acttagcagt gtttttcaga
    21781 cacaagtagc ctgccgtgcc cccaaagaac acttagtgac actaccttta gagaaatatc
    21841 agtttaaaaa gagccgactg acaagtcaac aagaaattgg tcaatcttgt ctaaagacca
    21901 cacaattcct ttctgttttg gagaacaaag acacccagca aaaagcaggt aaggttagca
    21961 cacctcacat tcttatcacc agttaccagc actatttatc tctgcccttg caggtttgtt
    22021 ctcaggcatt tgattttaaa aaaggagacg atatcttctt gcctcagtgg ctccaagtca
    22081 aagatgccca aggttctttt gtgaaaaaag cttttccaat gacatggtac ctaaaagaga
    22141 aaatctttgc caagcctatt cttgtcacgg gctatgtttc ttgttttggg caatcaatac
    22201 cggttgaggc aaggcttaac ctagcacaag ctagcaaaag acggcaccag gatctcagtt
    22261 tagtcgccaa gcaatccctg gccgcaagtc aaaaaaggct aacttattgc taccaatatg
    22321 atacggtgca agccatagga gccattagct tgcaaaatca cacaggcaca tctcttagtg
    22381 tttctgtggc aatcagttat ggtagtcaga gctctattaa gcaagaaacc ttgatgctag
    22441 ctgatagcca cttgagccag ttagaagagg ttattttctt cgatgatatt ttgactgttt
    22501 tgtatctggc agtgaccctt gaagtcattg aaggacctga cctaactgaa gacagtattc
    22561 aaattggcct ttgggattta gcatgaagca tgagtaaaag aagacttctt tggcaccagg
    22621 tctgatgaat tctgtaaaat aaggtataat aaaaaacaaa taggcgtcct ttattacgtg
    22681 aaaggcgcct ttacaaggtt gaaatggaaa gtgagatttc taaatgtcag aacgtttatc
    22741 aggccacacc ctgttggtct ctttgcttgc tacccctatt cgtcatagtt tgtctcccaa
    22801 aatgcacaat gaagcctatg ctaaactggg gctggattat gcctaccttg cttttgaagt
    22861 agggacagag caattagcag atgccgtgca agggattcgt gccttaggaa ttcgtggctc
    22921 caatgtgtct atgccaaata aagaagctat tttaccctta ttggatgact tgtccccagc
    22981 tgctgagttg gtcggtgcag tcaatacggt tgtcaataag gatggtaaag gacatctcgt
    23041 ggggcatatt acagacggta taggagcgct cagagccttg gctgacgaag gagtgtcggt
    23101 aaagaacaaa atcattaccc tagcaggagt tggtggggct gggaaagcta tcgctgtcca
    23161 gctcgctttt gacggcgcca aagaggttcg tttgtttaac cgacaagcta cacgtctaag
    23221 tagcgttcaa aagcttgtga caaaactgaa ccagctaaca aggactaaag taacccttca
    23281 agacttggaa gatcagactg cctttaagga ggccatcagg gaatctcatc tatttattga
    23341 tgctacaagt gtaggaatga agcctttaga aaatctaagt ttgattaccg accccgagct
    23401 cattcgccca gacttggtgg tctttgacat cgtgtacagc ccagcagaaa ccaagttact
    23461 agcctttgcc cgtcaacatg gcgcccaaaa agtcattaat gggctaggga tggtgcttta
    23521 tcaaggagca gaagctttta aattaatcac tggtcaagac atgccagttg acgctattaa
    23581 acctctttta ggtgatgagt aacacttttt aagtaagctt aattatgata tattaataag
    23641 agatggagca gtcatcatgg gctgctaaaa ttctttttgc gagagctgtt tttaagagca
    23701 aaaagcttat ttgaagagcc ttatctctaa cgtgatacaa gtcatagttc ctttgaggtc
    23761 tgccagataa cctaccgttt ttttagaaaa gaagctctta taaaaggaaa agttcaatga
    23821 ataaaggaga atagcaatgg taacaaagga agttgggcat gactttttag cacgtctagg
    23881 aaaaaaacgc ttaagacctg gcggtgttga ggcgacaaac tggttgattg aacaaggaca
    23941 attctctcag gattgtcacg ttttagaggt tgcctgcaat cgctgcacga cagcaataga
    24001 gttagccaaa accttcggtt gtcagattga tgccgttgac ttaaacccca aggttgtcaa
    24061 agaagcacaa gaaagggttg ctgttgaggg gttaacccgt cacattacag tatcccaagc
    24121 caatgcttta tcactaccat ttccagataa ccattttgat attgtgatta atgaagccat
    24181 gttaaccatg ttgaacgccc aagccaagga gaaggcactc aatgaatatt ggcgtgtgtt
    24241 aaaaccaggc gggcgacttt tgacacatga cgtagcttat gaagatccaa aaacaagaca
    24301 agtacttgac gagttacgtc aaacgattca tgtcaatgtt gctcccttgt cactaacagg
    24361 ttggcaagcc ttatatcaag aacacggttt ttctcaagtg acttatcacc atgggaaaat
    24421 gtctttgatg acacctcgtg gaatgattaa ggatgaaggt cttatgaaca ccctgaacat
    24481 tatgagacga ggccttaaga aagagaacag acaacagttt ttaaagatgc gtcgtttttt
    24541 taccagaaca ggcaaaaatc tctgctatat tgctgtaaaa agtgtaaaat aaaccttaga
    24601 ccaacctgtc catacaacta aacagaccat agaggagttc gaagatgtct tatatcaata
    24661 atattgagca cgcgaaggtt cttgatttga cgcaagaagt aatgattgag caagatcaaa
    24721 tgttaagtag aacactagtc caaaggcaag acttaggaat aacagttttt tccttagata
    24781 agggccaaga aattgggcga cactcatcac caggagatgc catggttact atcttaagtg
    24841 gcttagcaga aatcaccatt gatcaagaga cctaccgggt tgctgaaggt caaaccattg
    24901 tgatgccagc tgggattcct catgccttat atgcagtaga agcctttcaa atgcttttag
    24961 tagtagtaaa accggaggct taacatgatt gaaaatctct ctcaattggt gcaatatcat
    25021 gatcatcagg tggctagccg atccttgagc cgtctactgg gattatctca atctattgtt
    25081 ttatatgcca tggcccaagg agaaagcatt agtcaagaga ctagtccaag agataaagta
    25141 atacttgttt tagaaggtca gctcattttc gatttagagg atcaaaaaca ggtcctaact
    25201 caagaaagtc tcatagccat acctgcccaa aaagtccatc atttagaagc taaaaccgat
    25261 tgtaaactat tacaagtgct tttagattaa gggcttattg tcaactgtat tgggtggcct
    25321 atggaaaagc aaaagagaag gtgatgctca tcttctcttt ttacgtattc aaagcgatga
    25381 caatacgaat tttaaagctt ggctttctca tctccagatt aagcccttta gcttggttta
    25441 ttttagaatt cactaaaaaa accttaatga gtttcctatc tccttatagg tttctcatta
    25501 aggcttttta gacgaaataa ttgaacgaca ggcaaaagaa agatcttttt acgagtgata
    25561 ccgttctcct atagttccat aaatcctctt tttgatgttg ctgttagtta ttcttagcta
    25621 aaagttatat tgttatcaag acttgtcttg tagtaacatg ttttaggagt tccaggatac
    25681 cgttattctc ttagcaagct taactagcta gagtggagtc actatttata ataaactgtc
    25741 gagcttctcg acaaattggt gatcgtcttt gttaatggct agggtggtaa aaccggtttc
    25801 tgtgggtaat ataaagataa tatgttgctc agaattcttc ttatctgttt taaagacgtc
    25861 aaagagggat gtcgcagaga catcagctct ttcaagtgtt gttggtaact ggtaacgttc
    25921 aaaaacttga aggaggctat ccaagtcctc ttttggcaag agtcctttgg aaacagccag
    25981 tttagcatca accaccatac cgatagcaat ggcttcaccg tgatggtaaa aatcatggtg
    26041 gcagagcgat tcaatcgcgt ggcccaaggt atgcccaaaa tttaaagaca tgcgcaaacc
    26101 attttcaaat tcatcttgtt caacaatctg ttttttattg gaaatggatt ggtaaatcag
    26161 atgttcaagt ccctgcttat cggtttcttt ttgaaaatca cgtaactgct gaaaaagcgg
    26221 tctatcatga atgaagccga ttttgagcat ctcactgatg ccgcaggaga attcccgttg
    26281 cggtaaggtt tccaaaaagg tggttgaaat aatgatagct tctggagggt aaatgctgcc
    26341 aatcatattg gttagacttt taaaatggac tccaactttg cccccgatac tgctatccac
    26401 ctgactaagt aaagtcgttg ggatttgaat gtagggaata ccacggtaat aggttgcagc
    26461 gacaaaacca cccagatccc caacaacacc accaccaata gtaacaatca tatctttttt
    26521 ggaaaaattt tcagcgatga gctggtcgta gatagcactg acacgttcca aggatttggt
    26581 ttgacctccc ggggggcaga catggacaaa agcgttgtat tgctgagcaa attcttcaaa
    26641 gagagtctga tacaagtggt agaccgtttg atcggtgata aacaagagtt tacgctgctt
    26701 gcgctcacca aggcaatctg ctaaggtttt taaaacatgg tcggtaaaca ggatatcata
    26761 atccttgacc cgagaatgga catgaagtgt ttgtggcata agcactcctt tcatcagtac
    26821 taggtaacag agataacgca gtgatattta gagcttaatc ttgccaaagt tcctgcccca
    26881 actgttctaa ttgcttataa tcaatttgct gggcagcatc tgacagcgca tggtcgggat
    26941 caggatgaac ctccatcatg atgccattgg caccgacagc cttcgctatc ttagcagcag
    27001 gtaagagtaa atctcgtctg cctgtcgaat gagacacgtc cacaataatc ggtaaatctg
    27061 tcttttgttg aataataggg actgccataa tatcaagcat atttctagtc tccacatcgt
    27121 agccacgaac gccacgttcg cataagataa tgttagattt tccagtgtct tgtaagtagg
    27181 aaagggcgcc caaatattcc tcgatagtag ccatcaagcc tcgtttaaac aaaataggct
    27241 tatcgatgtg tgacaaggtt tttaaaaatt caaaattttg catgttgcgg gcaccaacct
    27301 gaatgacatc gagatagtca taggcttctt ctaattggcg ctcggacatg atttcactga
    27361 ccgatagtaa gccaaattcc tgacaaacct catgcaagta acgaattcct tgcaggccaa
    27421 ggccttgaaa agaagcagca gatgttcttg gtttataggc gcctcctcta aaatagttgt
    27481 aaccaagttt tttggcactt gaagctgcta atctaatgtg atcataagat tcaatggaac
    27541 aaggtccaac aataaaatta ttcttagaac aagtcttatt ttgaaagtca gacataatgt
    27601 caatcattcg tttgattcct ttactaattt tgtatggcgt gctctatggg ataacgtctt
    27661 atttaggaat acaaaatctc gttgttatcc atgaagcacc cttagcctgt gaaatgatac
    27721 cataaacaag atgaaatagc aagtaaaccc tagattgtct atgttcttag tcatttttat
    27781 taaaaaaggc ttactagcta taaaaaaata ctgccctaaa tcttattagg acagtatttt
    27841 tttatagatg ccaccaccga gaatcgaact cggaacgaag cattaccatt gctttattat
    27901 accatttaac tacagcggct acctttttat aatactataa gttattaatt gatgcaagct
    27961 tttcttaaaa atatttcttt aattgtttat catcaaaatg agagtaccag ttattaataa
    28021 catggcacaa gaggcctgcc ttatggtata atggtaaaga tgatttcaga aagaggaagc
    28081 caagcatgtc ttatgaaaaa gaatttttaa aagattttga agattgggtt aaaactcaga
    28141 ttcaagtcaa tcagctagcc atggcaacca gtcaagaagt tgcccaagaa gatggcgatg
    28201 aaagggctaa agatgccttt attcgttatg aaagtaagtt agacgcctac gaatttttac
    28261 taggtaaatt tgacaattat aaaaatggta aagcctttca cgatattcca gatgagttat
    28321 ttggagcaag gcattattaa gaaggagaca cgaaatagtg gcaaaacaaa aaaatcgtaa
    28381 aaaagcattg aaattagaaa tgaagcgtaa tggcttgtta aaaaaagcag gtcaagtttt
    28441 tgataaggca gttgaaagtg ttgaaacagc tgtggataaa accatttctg ctggtaaaaa
    28501 tcttgtggaa aaaggcagcc aaacggttga aaacctgaca gcaagcaagg aaagacttac
    28561 tcttgatgag tttgcagggc agccagttgt agctggtatc cgctctgacc ttgtcgaaac
    28621 cctatatgca gaaggcatcc attcagcgca agcttttaag gaatggacag aaaaagacct
    28681 ccttgctctt aagggcattg gcccagcaac ggttaaaaaa ttggtcgaaa atggcgcaag
    28741 ctttaaaaaa tagtcatctt ctcgttgctt aatggctata aatttgttag aatattagca
    28801 atcagaggtg aattgagttg gtctgttaca gagagcggtg gtgttgagaa atccgcacag
    28861 atgtcaaggc tagtagctga ggatcagaaa tcagatatga aaagtagcag acccatttta
    28921 tggtctgaaa cagtggtggt accgcggaaa tcgtaacacg aaattcgtcc ctgtctaggt
    28981 tatctaggca gggattattt ggtttcattt gaaagaagat gatggcttat tgttaaaatg
    29041 ttgttagaag tatataatag aaaaactttg cccaaagtgg aaacagaacg gctgctatta
    29101 cgtcaacgaa aaggggacaa ggcattgttc cagaagcggc ttcagctctg attgaaattg
    29161 gttttacctt acttgatttg cataaaattg agctgggttg ctacgactac aacaagcaaa
    29221 gtcaggcagt ggctcgcaaa ttaggcttta ccttagaagc caatgcccgt gaccgtaagg
    29281 acgttcaagg tcgccgctgt ggcgacatgc gttttgggtt actgagaagt gagtgggagg
    29341 agcagaaaca aaaatgaacc ttatcatcat tggtgctcaa gcgtcgggca agatgaccat
    29401 tgggcaagaa gttgccaggc agacaggcat gactttgttt cataatcacg attctattga
    29461 ctttgtttta cggtttatgc cttggtctca agagagcact gccttgattg aacgtatccg
    29521 ttttgctttt tttgaaacct ttgctaagac aggtcaagac atgattttta ctattgtaat
    29581 tgacttcaat gatccaaatg atgtagcaat gcttgaaaag attcaggctg tttttcagtc
    29641 ttatgaccaa gaggttctct ttgtcgaatt aaaaacagat atagaggaac gtcttaaacg
    29701 caatcgcaca gaaaatcgtc tcaaacataa acctcttaaa cgcaacatcg agtggtcaga
    29761 acaagatatt caatccacga tggcatatgc tgtttttaat ccagaagaac cacccaaaac
    29821 gctcacgcat taccaaaaaa tcaataatac ccagctcacc gctgctgaaa cagcgcagct
    29881 tattatccaa aaaatgactc atatcaagga gaactaagat gacagaacta tcacctaaat
    29941 acaatcctgc cgaggttgag gcaggtcgct atcaaaaatg gcttgatgca gatgttttca
    30001 agccatcagg agaccaaaaa gcaaaaccgt attctatcgt gattccaccg ccaaatgtga
    30061 ctggtaagtt gcacttagga cacgcctggg atacgacgct tcaagatatt atcattcgtc
    30121 aaaaacgcat gcagggcttt gatacgcttt ggcttccagg gatggaccat gcaggaattg
    30181 cgacacaggc taaggtagag gagcgtctgc gcgagcaggg gatttctcgt tacgaccttg
    30241 gtcgtgacaa attcctagac aaggtctggg agtggaaaga cgaatatgcc actacgatta
    30301 aagagcagtg gggcaaaatg gggctttctg tggactacag ccgtgagcgc ttcacccttg
    30361 atgagggctt gtcaaaagca gttcgcaagg tttttgttga cctctacaaa aaaggctgga
    30421 tttaccgtgg tgaattcatc atcaactggg atcctgctgc cagaactgcc ctttctgaca
    30481 tcgaggttat ccacaaggat gttgagggag ctttctatca catgaactat atgttggaag
    30541 atggctcacg cgcccttcaa gtggcaacaa cgcgaccaga aaccatgttt ggagacgttg
    30601 ccgttgccgt aaacccagaa gatcctcgtt acaaagattt gattggcaaa aatgttattt
    30661 taccaatcgt gaataaattg attccaatcg tgggtgacga gcatgctgac cctgaatttg
    30721 ggactggagt tgtgaaaatc acgcctgccc atgatcctaa cgatttcgag gttggtcaac
    30781 gccataatct accacaagtg aatgtcatga acgatgacgg taccatgaat gagttagctg
    30841 gcgactttgc aggcatggac cgttttgaag ctcgtcaagc taccgttgct aaacttgaag
    30901 aacttggtgc cctagtaaac atcgaaaaac gtgttcactc agtaggtcac tcagaacgtt
    30961 ctggtgcagt cgttgagcct cgtctatcca cccaatggtt tgtaaaaatg gatgagcttg
    31021 ctaaacaagc tatggacaac caagaaacag atgaccgagt agatttctac ccaccacgct
    31081 ttaatgatac cttccttcaa tggatggaaa atgtccatga ctgggtaatc tcgcgtcagc
    31141 tttggtgggg gcaccaaatt cctgcttggt acaatgcaga aggtgagatt tacgttggcg
    31201 aagaagcacc agaaggtgat ggctggactc aagatgaaga tgttcttgac acttggttct
    31261 catctgcttt atggccgttc tcaactatgg ggtggcctga cacagatgta gaagatttca
    31321 aacgttattt cccaacctca accttagtaa caggttatga catcattttc ttctgggtgt
    31381 cacgtatgat tttccaatcg cttgaattta ccgggcgtca gccattccaa aatgtcctga
    31441 ttcacggtct tattcgtgac gaagaaggac gcaaaatgtc taaatcattg gggaacggga
    31501 ttgatccgat ggatgtcatt gagaaatacg gtgccgatag cttacgttgg ttcctctcaa
    31561 acggctctgc cccaggacaa gacgtgcgtt tctcatacga aaaaatggac gcctcttgga
    31621 atttcattaa taaaatttgg aacatttctc gctatatcct catgaataat gaagggttga
    31681 cattggaaga agctgaaagt aatgtggcta aggtagctgc ctcagaagct ggaaatgtga
    31741 ctgaccagtg gattctccac aatctcaatg aaaccatcgc taaagtgaca gaaaactttg
    31801 acaagtttga gtttggtgtg gcaggacaca ttctttacaa cttcatctgg gaagaatttg
    31861 ccaactggta tgtggaattg accaaggaag tgctgtatag cgacaacgaa gctgaaaaag
    31921 ttatcacgcg ctctgtcctt ctttatactt tggacaagat tttacgtctc cttcacccaa
    31981 tcatgccatt tgtaacagaa gaaatttacg ctcaatatgc ccaaggttct attgtgacgg
    32041 tggactatcc tgtggttcgc ccagcttttg aaaatgaagc tgcgcataaa ggtgtggaaa
    32101 gtctgaaaga tcttatccgt gctgtacgaa atgcgcgcgc tgaagttaac gtggcaccat
    32161 caaaactaat caccattttg gtgaagacag cagatagtga gttggaagac ttcttcacca
    32221 gcaacgtgaa ctacatcaaa cgtttcacca atcctgaaaa attagaaatc agctcagcca
    32281 ttgctgcgcc agagctggct atgaccagca tcatcacagg tgctgaaatc tacttgccac
    32341 tagcagattt gcttaacgtg gaagaagaac tcgctcgcct agataaagaa ctggctaaat
    32401 ggcaaaaaga attggacatg gtcggcaaaa aactcggaaa cgaacgcttt gtagccaacg
    32461 ccaaaccaga agtcgtccaa aaagaaaaag acaaacaagc cgactaccaa gccaaatacg
    32521 acgcaaccca agaacggatt gcagagatga agaaaattaa atcatagtgt ttagaacgca
    32581 gttgaaaaac tgtgttcttt tcttactaat agagatatta gattgaagtt taattatgag
    32641 aaaaacgctt tctttattta aagagttatg ttacaatact attacaatca tcgtacaaat
    32701 agtgttattt tgagaggcat atgagaatga ttttagcaca ctatgactgt aaaaaagata
    32761 aaaagcaatc tttagatgag catttatggc atgtggcctg ttctagtcga caggaagcat
    32821 ctataattgg tcaaggagat gtgctttttt taattggtct ttaccacgac ctgggtaaag
    32881 ctgatcgaac ctttcaagat aaattattaa ataatccaaa tcggcatgtt gatcactctt
    32941 atgcaggggc aaaatactta tgttctatta ttgggcctca tctaaaaaac cgaggggttg
    33001 ataaaaatga gagaatgaca ttcaacgaaa tggtggggta tgtcatctct gctcatcatg
    33061 ggatgtatga tttatgctac tattttgacg atgctgaata ttatggcttt aataagttta
    33121 aaaatcgtat caatagagac ttagatggtt atcactatca tgaagatatt aaagggtacg
    33181 ctctaaaatt agaaaaaaaa ttatgtgatt atggctacaa agatttaagg gagcttattg
    33241 ataaagcttt tgataattac caacaagcca tgtcttcctt aaactggcaa gataagagtg
    33301 agtgggatta ttatcagtct tgtatggtga gactttactt gtcactctta aaaaacgctg
    33361 atattttgga cacagtaaat gcctatggcc ttaagataag tcctatggat aaaacagagc
    33421 gatcctttct aaaacactcc tatttagcgg ccattgaaca aaaatatgct agctttggac
    33481 agccaaacaa tcagttgaac actattcgga cagaaatcgc tgagcgtgtt aaagaaagag
    33541 gtaaacgaga ttccaagggg atttatcgct tagatttacc gacaggagct ggcaagacta
    33601 atcttagtat gcgttatgcg tttcaccaat tagttcatca cgacaaatca aggttttttt
    33661 acataacgcc ctttctttcg gttcttgaac aaaatgcttc cgaaattaga aaagttacag
    33721 gtgaccttgg cgtcctagaa caccattcca atgtggtgaa acaggctaat gaagatgatg
    33781 atgacaagga cagtttattg tcagcttatc ttagtgatag ctgggacagt caagtagtct
    33841 tgacttctat ggttcaattt ttccaaacac ttttcaaaac aaaatcagct aatctgagac
    33901 gtttttcaag tttgattaat agtgttgtga ttctagatga agttcaatcc ctgcctattg
    33961 aagtcaccac tttgtttaat ttaacgatga attttttaaa taaagttatg gatacaacca
    34021 tcgctctttg cacagcaaca caacctgctt atgattcttc agagattgac catcgtatct
    34081 gttatggagg aaacttggga gaattagctg aaatcgttga gttaacgatt gaagaaagac
    34141 agattttttc aaggacagag cttagaaaat ttgatgatag tgatcagaaa gttcacttga
    34201 ctgatgttat taaccttatt ctaggtgagg aaaactcagt tcttgctatt tttaatacga
    34261 aaaaaacggt tcataactgc tatactatgc taaaagacat gactgataga ccggtctatc
    34321 agctttcgac aaatatgtgt gcgcagcata gacttgactt gattgctaag atcaaaacgg
    34381 agttacaaaa taatatccct attatttgta ttagcacgca attaattgaa gcaggtgtag
    34441 atgttgattt tcatcgcgtc attcgttcct actcagggat tgattctatt gttcaggctg
    34501 ctggacggtg taaccgagaa ggcaaacgag ataaagggca agtcactctt gtcaatctga
    34561 ccaatgaaga ggaaaatatt tctaggctga cagaaataaa agctaaaaaa gaagccacag
    34621 aatctattct tcataagatt gggtctccaa ttgatatctc aactttaaac cgtgactttt
    34681 ttgagtatta ttatgccaat aatcagggac tgatggatta tcctttggaa gacaacctat
    34741 caatctacga ctatttaagc cttaatattt atcagacggc aaataaaaag ttcaaaggta
    34801 agttaaaaca agcttttaaa acagcaggag ccaaaatgaa cctcatcaat aatgacatga
    34861 taggaattct tgtatcttat ggcgaagctg agaaaaaatt ggcttattta gaagaattag
    34921 gtgtgtcaca ttttttatca gcaaaagatt atcaaacgat aaaatcatta ctaaaagagt
    34981 tacaaccttt tacggttaat gtccgcgaga acgatcctct ccttgatgca acaaaatctt
    35041 ttctaaatgg tcaggttctg gttttgacgt cggagtatta tgacacagaa agaggagtta
    35101 aatacgattc agctaacttt tacttctaac tcaaaacgaa agcagattaa cgaaaggttg
    35161 ttagaggacc ttgttaacct gccaatcatc attaataatt attatcaatt tagactattt
    35221 aataaaatta gattacaaaa aaacagaagg aggaaagtag cttgtacaga tctagagact
    35281 tctacgtgag agtaagtggt cagcgagctc tttttacaaa tccagccaca aaagggggat
    35341 cggaacggtc atcctattcg gttccgacta gacaggcact gaatggtatc gttgatgcca
    35401 tctattataa gccaaccttt actaatatcg tcacagaggt taaggttatt aaccagattc
    35461 aaaccgaatt acagggtgtc agggctctgt tacatgatta tagtgcagat ttaagttatg
    35521 tatcctattt gagtgatgtt gtttatctaa tcaaatttca ttttgtttgg aatgaagata
    35581 gaaaagattt gaactcagat agacttccag ctaaacatga agccattatg gagcgttcta
    35641 ttcgtaaagg gggacgtcga gatgtatttt tgggtacaag agaatgttta gggtttgtag
    35701 atgatatcag ccaagaagag tatgagacta ctgtgtcgta ttataatggt gtcaatatcg
    35761 acttgggaat catgttccat tcctttgcct atccgaagga caaaaagaca ccattaaaat
    35821 catactttac aaagactgtg atgaaaaatg gagtcattac gtttaaagca cagtctgaat
    35881 gcgatattgt taacacgctt tctagttatg cttttaaagc accagaggag ataaaatcgg
    35941 ttaacgatga atgcatggag tatgatgcca tggagaaagg agaaaactga tggatttttt
    36001 tacttctctc ttgaagactt atgaaaaagc agagctagca gacttggttg atcaccaaaa
    36061 aagaagtaat gagccggttt tactgccgat ttatcatacg agtttaaagt caaatggcaa
    36121 aaatatcatt tcagtgaaac ttgacaaaga tggccagttt cacaaggcag aatttatggc
    36181 agataagcaa atgattattt ttcctgtaac ggctgattct gttgctaggt caggtagtca
    36241 tcctgcaccg catcccctag tcgataaatt tgcttattat agtgctgaaa tggggcagac
    36301 tcagtatgat tcttttcata agcaactgaa taactggatt gattattgtg aggagggtga
    36361 tgtcaagaaa tttttaacct ttgttcagca gttcattttg aagccagaat ttctaacatt
    36421 gattcttgat tctttaattg gtcctgatta tcaacataat caattaaaag tcacattttg
    36481 tgatgccact ggaaaagaaa aattaattga tttatcagct tgctttttag aattttcaat
    36541 tgatcagttc cagggcttta aaaatgaatc ggtttcgaca tttaaagcct tacaccaatc
    36601 ctatatttct tttgttgaag ccaagcgtga aaatctcggt atttgtaata ttagtggacg
    36661 agaggaacag cttaccgata agcatagagg tttgatgggg aatgctaaaa tcatctctgt
    36721 tagtaataaa agagaagctt ataaaggacg ttttagagaa cgcgaagacg tttttagtgt
    36781 tggctatgaa acttccgaaa agattcattt aatgctcaag taccttttag aaaataaaaa
    36841 taccagtact tggttagggt cttctcaata tttaatcaac tggttcagcg atgatttaac
    36901 aaatgatagt cggttggata ttgtatcacc aatctttgat gatggacttg aagaagatga
    36961 tgatgacgat acgcctcctg ttataacatt agcaactgaa gacaataaaa gaattggtaa
    37021 atcattcatc aagggacaaa aattatttgc taatgatgcc acttactacg ttgctatttt
    37081 gaataaaacc agcaatgggc ggattgcttt aaaatatttt cgtcagcttc aagcgtccca
    37141 attactcacc aatcttaaca agtggcagga aacatacagt tgggagtcgc gatctaagtt
    37201 tgggaaaagt cgcttaagaa cccctacttt tcatgacatc cttaatgtgt cctacggggt
    37261 tgatagggat cgcttccttg aattagataa tgataacttc aaaagtgatc aaattcaaaa
    37321 gttagtggca agtttgattg atggtaaacc gatgccacag tccattgtca aaaagttagg
    37381 taacaatgtt aaagaacgac atcgttaccg taagcactgg tatcaagttg agcaggtctg
    37441 cttagcaatt ttacacaaac aaaatgggga ggaattttca ccgatgctag atcataccaa
    37501 tcaaaatcgt tcctatcttt ttggacgatt attagcaatt tttgaattaa tcgagacctt
    37561 gcgttatggc ttggatggaa acaataacga ccgtattacc aatgctgaac gttattggac
    37621 agcctatact ggacaaccaa caaaattgat gatgttattg gaaaataaaa ttaagcctta
    37681 cgaagaacca ttgaaattaa atcgtcgtgg cagttggatg aaattagaaa aagaaaaaga
    37741 agagatttta gaactgttaa atcctctgtt agaaacagaa acaatggaaa aacccttaga
    37801 ttaccgcttt atttttgggt attatgctga gaaaaactat tactatacaa aacaaaacac
    37861 ggaagtaaca gaaagcgagg agtaaaaaga tgttggaaca caaaattgat tttatggtaa
    37921 ctcttgaagt gaaagaagca aatgcaaatg gtgatccctt aaatggaaac atgcctcgta
    37981 cagatgccaa aggatatggt gtgatgagtg atgtctccat taaacgtaag attcgtaatc
    38041 gtttgcaaga tatggggaag tctatttttg tgcaagctaa tgagcgtatt gaagatgatt
    38101 ttcgttcact ggaaaaacgc ttttcgcaac attttacagc taagacacct gacaaagaaa
    38161 ttgaagaaaa agcagatgca ttatggtttg atgttcgtgc ttttggacaa gtttttactt
    38221 atctgaaaaa atcaattggg gtgcgtggac cagtttccat cagtatggct aagtccttgg
    38281 agccaattgt catttccagc cttcaaatta cgcgtagtac caatggtatg gaagctaaga
    38341 ataatagtgg ccactcttct gatacgatgg ggacaaaaca ttttgtagat tatggtgtgt
    38401 atgtacttaa aggttctatc aatgcttatt ttgctgaaaa gactggtttt tctcaggaag
    38461 atgctgaggc tattaaagaa gttttggtta gcttgtttga aaatgatgcg tcatctgcac
    38521 gtccggaagg ctctatgcga gtttgtgaag tcttttggtt tacgcattca agcaaactgg
    38581 ggaatgtttc aagtgcgcgt gtctttgact tgttagagta tcatcaatca atggaagaaa
    38641 aaagcactta tgatgcttat cagattcatc taaatcaaga aaaattggct aaatatgaag
    38701 cgaaagggtt aacggttgaa atcctagaag gactctagta tggtttatgc cgaagatgat
    38761 tatttaatgc tatcaggtat tcagcatttc caattttgta aacgtcaatg ggcgttgatc
    38821 catattgagc aacaatggct tgataatgaa gcgacagcgc atggacagat tttacatact
    38881 aaagcagata acccttacat taaagaaaag cgaaaagatc ttttggtctc acgtgctatg
    38941 cccatttctt ctgcagaact tggtctttca ggaattatgg atgttgtgga attttataaa
    39001 gatgatcaag gtgtgtcttt gaggggaaaa cgtgggaaat ggttaccaaa agttgtggaa
    39061 tacaagcgcg gaaaacctaa aaaagatacc agagatattg tccagttggt ggctcagacc
    39121 atgtgtttag aagaaacgct agactgcgac attaacgaag gttgtcttta ttaccatagt
    39181 gtcaatcaaa gagtgattgt tcctatgaca tcagctttgc gtcaagaagt gaaggaatta
    39241 gccgcagaga tgcatgatgt ttatcagagt caaatgctac ctaaagcagc ttattttaaa
    39301 aactgtcagc tttgttcttt agtcgatatt tgtaagccca ggttgagtaa aaaaacaagg
    39361 agtgtgtcgc gttacatcaa tgaggctatg accagtgagg agatggacct atgaaaaagt
    39421 tgctaaatac cttgtatttg acgcaagaag atttttatgt cactaaagag ggcgataaca
    39481 ttgttatcaa gcaagaaggt aaggttctca aacggtttcc gtttcggatt attgacggta
    39541 ttgtctgttt ttcttatttg ggtgtgtcgc ctgctttggt gaagttatgt acggagaatc
    39601 agattaattt atcgtttcat acaccacaag ggcgtttttg tggtcgctat attggttcaa
    39661 ccaatgggaa tgtgttgttg cgtagagaac attatcgttt atctgatcgt gaggaatctt
    39721 tggaatacgc aaagcggttt attttggcta aaatttccaa ctcaaggaaa tacttgctac
    39781 gctttaaacg agatcatcgt caacagattg ataccaagct ttttgaggct gttaatgacg
    39841 aattgatatg ggctttagag atggttcagg cagcagataa taaagactct ttaagaggga
    39901 ttgaaggcta agctgctaat cagtattttc gcatatttaa tgacctggtg ctgacggaca
    39961 aaaaaacgtt ttacttccaa ggtcggagta aacgaccacc cttagattgt gttaatgccc
    40021 tcttgtcttt tggttacagt ttactgacct ttgaatgtca atctgccttg gaagctgtcg
    40081 gattagacag ttacgttggt ttctttcaca cggatcgtcc tgggcgtgct agtttagcgc
    40141 ttgatttagt tgaagagttc cgctcatata ttgtagatcg ttttgtcttt tcattaatta
    40201 ataaaggaca acttcagaaa aaacactttg aggttaaaga aaatggtagt attttattga
    40261 cggaaaatgg cagagctatt tttattgatt tgtggcagaa gcgtaagcat actgaggtag
    40321 aacatccttt tacaaaagag aaagtaaaac ttatgttatt accctatgta caagcgcagc
    40381 ttttagctaa ggccatacga ggagatttag aaagctatcc accttttatg gtttaggaga
    40441 tgttatatga tggttttagt cacttatgat gtaaatacgg aaacacctgc tggtagaaaa
    40501 agattgcgtc atgttgccaa actctgtgtg gactatgggc aacgtgttca aaattctgtt
    40561 tttgaatgtt ctgtgacacc cgcagaattt gtggatataa agcaccgctt aacacaaatc
    40621 attgatgaga aaactgatag tattcgcttt tatttattgg ggaaaaattg gcagaggcgt
    40681 gtggaaacac ttggtcgctc agacagctat gacccagata aaggtgtctt attattgtaa
    40741 aaatctcttg tgcgaagcta gctttcacag aaaaaccttg cttgctcgcg caaaaataac
    40801 ttaaaaaaga agcgaaatgg agataaaaag gcttaaaaca cctctatgtg tgccatccgt
    40861 ttctctataa actgtgtcat ttggcgcagt ctcacccttc atgggtgagt ggattgaaat
    40921 atccgatttt aaccccatat tttctacgag ataaccgtct cacccttcat gggtgagtgg
    40981 attgaaatat cagctagctc gttgagtagg ccgttgaact cgtgtctcac ccttcatggg
    41041 tgagtggatt gaaatgccaa tgattacaat tgatccataa tggtcgtagt ctcacccttc
    41101 atgggtgagt ggattgaaag atgaacccga cctcattaaa agagaggtcg ggtttttaca
    41161 tgcctttagt caaccattta tctgatagcg tatcaaattc aagtttttgc atgttctagt
    41221 ctatggtttg cgccactagc tttcggtaaa ctaagggtaa cttaagagag gagttattta
    41281 tgacactatc acttgtatta atggtatcgg tttttggggc aggcttgtta tcatttttct
    41341 ctccgtgtat ctttccggtc cttcctgtct atttaggcat tttactggat gcagatgatt
    41401 caaagacgat tactatattt ggtaaaaaac tctattggta tggcattgtc aaaactttag
    41461 cctttatttt tggtctatct actatttttg tgattttagg ttacggggct ggttttttag
    41521 gaaatatcct ttatgcggta tggtttcggt acttactggg agccttggtc attatcttgg
    41581 ggattcatca gatgggcctc attaccatta agagcttaca atttcaaaaa tcactgactt
    41641 tccataataa caagaatcgc aacggtttgt tcaatgcatt tatccttggt ttaaccttta
    41701 gctttggttg gacgccttgt gtgggacctg ttttgagttc tgtcctagca ttggtggctt
    41761 cagggggaaa tggtgcctgg caaggtggcg ttttgatgat tatttatact cttggattgg
    41821 gcattccttt cctactcatc tcttttgcgt caggcattgt tttgaaacag tttaacaagc
    41881 tcaaacccca catactttta ctgaaaaaag taggaggcgt tctgattata gtcatgggaa
    41941 tcttgcttat gacaggaacc ttaaataact tagcacaact ttttggataa aggagaaaca
    42001 caatgaaaaa aggactatta gtaacaactg gtttggcttg tctcgggcta ctaactgctt
    42061 gctcaaccca agacaatatg gctaaaaagg aaataactca ggacaagatg agcatggcag
    42121 ctaaaaagaa agataagatg tcaacatcaa aggacaagtc catgatggca gataaatcat
    42181 ctgataagaa aatgaccaat gatggtccta tggcgcctga tttcgaactc aaaggcatcg
    42241 atggtaagac ctatcgctta tcagagttca aaggtaaaaa agtttatttg aaattttggg
    42301 cctcttggtg ttcaatctgt ctatcaacct tggcagatac cgaagacctg gctaaaatgt
    42361 cagataaaga ctatgtggtc ctaacagttg tctcaccagg tcatcaaggg gaaaaatcag
    42421 aagcagactt taaaaaatgg ttccaaggaa cagactataa ggacttacca gtcttgttag
    42481 atccggatgg caagctattg gaagcttacg gcgtcagatc ttacccaaca gaagttttca
    42541 ttggaagtga tggtgttctt gctaaaaaac acattggtta tgccaaaaaa tcagacatca
    42601 aaaagaccct taaaggtata cattaggaag gaccagctga taggcattag aaaaaaggag
    42661 ttgagtttat ggaacacaaa tggaaattat ggctatttat cgttggagtg gtcttgttaa
    42721 taggcggagc ttctgttctc attcagaaag gtcaagccaa ggcttttagt caaggcaagc
    42781 ctcaactacc agctaaaaaa gtcaaatcca ctaaagtaga tcccaatgcc cctgttgatc
    42841 aaaaagtgat ttacctggct ggaggctgtt tctggggcgt tgaagaatat ttttcacaag
    42901 tggatggcgt tctagatgcg gtgtcaggat atgccaatgg tagaggcgat accactaatt
    42961 accagttaat tcatcagact ggtcatgcag aaaccgttga agtgacctat gatgcgaacc
    43021 gtattagctt gaaagaatta ttactgcatt ttttccgaat tattgaccca accagtctta
    43081 ataagcaagg aaatgatcgc ggtagtcaat accgaactgg gatttactat actgacaaag
    43141 cagatttagc tattattgat gaggtcttca aagaaaaagc taaggattac aagaaaaaaa
    43201 tagtggttga aaaggcgcca ttgaaacact ttattaaggc agaagactac caccaagatt
    43261 acctcaagaa aaatccaaat ggctactgcc atattgacat caaccaagcg acctatcctg
    43321 tgattgatga aagcaagtac ccaaaaccaa gtgccactga gatcaaagca aaactatctg
    43381 cagacgaata ccgagtgacg caaaaaaacg aaactgaaaa agctttttct aatcgctact
    43441 gggattcttt tgatgcagga atttacgtag acgttgtgac aggagaaccg cttttctctt
    43501 caaaagacaa atttgaatca ggttgtggtt ggccaagctt tagccgcccc atcagcccag
    43561 acgttgtccg ctacaaggaa gataagagtt tcaatatgac gagaacagaa gtgcgcagcc
    43621 gttcagggaa ttctcatttg gggcatgtct ttactgacgg acctaaagac caaggcggcc
    43681 ttcgttactg catcaatagc ttgtctatta cctttattcc aaaagctgat atggaagcta
    43741 agggctatgg ttatttatta tcatctgtag aatagggtta ggcctaaaaa tctgatataa
    43801 tagaagaaag actagtatga gagggccatg caaggccctt tataaagata aggagacacc
    43861 gtgtgtactc attgttaatt gtagaagacg aataccttgt gcgccagggt attcgttctt
    43921 tggttgattt tagccagttc aagattgatc gggtcaacga agcagaaaat ggccagttgg
    43981 cttgggactt gtttcagaaa gagccttatg atattgtttt gacggatatc aatatgccca
    44041 aattaaatgg gattcaactg gcggagttga ttaaagagca tgcgcctcag acccatttgg
    44101 tttttttaac cggttatgat gactttaact atgctttgtc tgctttgaag ttaggggcag
    44161 atgattactt actcaaaccc ttttccaagg ccgatgtgga agatatgtta ggaaagctcc
    44221 ggaaaaaatt agaactttcc aagaaaacag aaaccatcca gaaattggtt gagcagcctc
    44281 aaaaagaagt atcagcaata gcaatggcta ttcatgagcg gttggcagat tctgatttga
    44341 ccctaaaaag cttggctcag cagcttggtt ttagccctaa ttaccttagc gtcttgatta
    44401 aaaaagagtt agggatgccc tttcaagatt atctggtaca agaacggttg aaaaaagcca
    44461 agcttctctt gttaaccagt aatcttaaaa tctatgaaat tgcagagcag gtcggttttg
    44521 aggatatgaa ttatttttct cagcgcttta agcaactggt aggcgttacc ccaagtcagt
    44581 ataaaaaagg aggccaggca tgaagcgtta tcccctactg gtccagttga tttcttatgt
    44641 ctttgtgatc gtaattgccc tcattaccat gcttggtttg ctttattacc agacgagttc
    44701 tcgtaatatc aggcaattaa ttgaacgtga tacccggcag agcattcggc aaagttccca
    44761 atttattgac gcttacatca agcctcttaa agaaacaact tcggtgctgg cgaaaaatac
    44821 ggaaattcaa gcctttgcta gtcaaattca tcaagaaaat gacaaacagg ttcttcagct
    44881 catgaagatg gttcttgcga ccaattccga tttacaagca gctgttctgg tgactaagga
    44941 tggtcgaacg gtgtctacca attctcagtt gaccatgaaa acctccagtg acatgatggc
    45001 agaaccctgg tataaagcag ccatagaccg tcaggccatg ccagtcttga ccccagctcg
    45061 gcaattatcc ctttcttcta aaaaagaatg ggtagtttct gtgacccaag aggtagtgga
    45121 tgctgctggt cataatttag gcgtgctaag acttgatatt gcatatccga ctattaaagc
    45181 gtctttagat cagcttcagc taggccgcca aggcttttcc tttattgtga atgataagca
    45241 tgaatttgtt taccatccca aaaagagtgt ttacagttct tctaaggaga tggctgcgat
    45301 gaagccttat ttagcgattc agaatggtta cactaaggac aagacatctt ttgtttacca
    45361 aaaactcatt cctaacagtc aatggacttt agtgggagtg gcgtcactgg atcagttgca
    45421 ccgggtgcag cgccaaattt tttggtcctt tcttggaaca gggcttctag cctgtctgat
    45481 ttgtggcttt gcaactgtct tagccttacg cagatggatt cgtcccattc aacaattgca
    45541 gcaagttatt cttgctattc aaaaaggaga tcgtcagtta cgtgcccaag aaacgggttc
    45601 tccagaattg acagaccttg cccaacagtt taatgcgctc ttagatcaaa ttgatagctt
    45661 gatggttgcc attgcggata aggaaaaggc gattgggcag tataggttac aagccttggc
    45721 tagtcagatt aacccgcatt ttctctataa caccttggac actattattt ggatggcaga
    45781 atttaatgac agcaagcgcg tggtagaagt gaccaagtct ctagctaagt attttcgttt
    45841 ggcccttaat caggggaacg aatacattcg tttggcagat gaactggatc acgttagcca
    45901 atacctcttt attcaaaaac agcgctatgg agacaagcta agttatgaag tgcaaggctt
    45961 agatgtctac gcagactttg ttattcctaa gcttatctta cagcccttag tagaaaatgc
    46021 tatctaccat ggcatcaaag aagtcgatcg caaaggcatg atcaaggtta cggtatctga
    46081 tacagctcag catctggtgt tgactgtttg ggataatggt aaaggcattg aagactcttc
    46141 actgaccaat agtcagagct tgttggctag gggaggtgtg ggccttaaaa atgttgacca
    46201 gcggttaaaa cttcactatg gtgaaggcta ccacatgacc attcatagcc agtcagacca
    46261 gttcactgaa atacaattaa cccttcctaa aatgcatgaa ttaatggcag acgacacaca
    46321 ggaaaatgag taaggttaca ggaagtgcat gtcagccatt tccctaagtt agggtattgg
    46381 agataagaac cttagaaagg atatcatgag tttagcatct gactatttta gccgacagac
    46441 ccccatagtt gaaaagctaa tggcttacgg ttttgaaaaa cgaaataatg gttacttcta
    46501 taacgaacgg tttatggaag aagaatttga ggcgcagctt aggattgatg aggctggcaa
    46561 tatctgggat cgggttattg attgtgactt ggaggaggat tatttgcctt tacaacaagc
    46621 agcctggcaa ggaacctata ctgggcaggt tagagcagcc tatttggaac tcttggagcg
    46681 cttatcagta gcctgttttg aagtcactcc ttttcagtca atgcaagcta atagacttgc
    46741 taagcatatc accaaagaat ggtctgaccc aatggactat ccttttgaaa agcacccaga
    46801 ccttgcaacc tatcgggtag agggcaaatg gtatgctatg attttttctc tcttggctga
    46861 taaattagac cagataccag agagattagt aggacagaca tgtgaagtga tgactgtcaa
    46921 agttaatccc aaggctttcc ctcagttact gcagcaagaa ggcatttacc cagcgtatca
    46981 catgtcaaag aaaaactgga ttagtattat tttggatgat aaggtaacag atgataagct
    47041 ttggacgtta gtaactcaaa gtcgtcaact agtcaaccca aacggtcttt ctaatcctaa
    47101 tggtcctgat tattgggtta ttccagctaa tttgaaatac tatgatattg atgcagaatt
    47161 tgcagccaat gatgtgattt tatggaccca aaaagctggt attgccgtgg gagactatgt
    47221 gctgatttat ataacagccc cagtcaaatc cattcgctat gtctgccaag ttctagaaac
    47281 caatatacct aacgaaggct atcgtaaaaa tcctaacatt gacaaactca tgcgtctccg
    47341 aaaacgccaa cagtacaagg atggtctctt gtcttttgac cttatgaaaa aacatggcgt
    47401 agctgcagtg agagggccaa gacgattaag ccctcaatta attgcatttt taaaggaaaa
    47461 agagtatttt aaagagaaca actaaaggag aataagagat ggttgaattt gtagcagatc
    47521 aaagtttttg ggaacttttt ccagatgcca aactaggtgt cgtcttatta aaggatgttc
    47581 agaatcaagc agagtcacca gaagatgtca aacagctctt agcagacagc catgagttag
    47641 caaaagctta tttaacagca gacaatttta gtgataatca ggtggttcaa gtctaccgca
    47701 aggcctatca acactttaaa accaaaaaag gagctcgctc tagcattgaa gcccttctca
    47761 agcgggtgtc aaatggtcaa agcattccgt cgatcaatcc gctagtggat atttataatg
    47821 cagctagtct acgttttggt ttacctgttg gagccgaaga tagtgacagt tttatcggag
    47881 atttgcgtct gacgataaca gatggtggtg acgactttta cttgattggg gatgctgaca
    47941 ataacccaac cttgccaaat gagctgtgtt ataaagatga tattggagcg gtttgtcgtt
    48001 gccttaactg gcgagatggc gaacgcacca tggtgacaga acacaccaaa aatgcatttt
    48061 tgattatcga agctcttgat caagaaggtc aaaatagatt gcaagaagct cttgacttca
    48121 ttgaaggcag cgcaaaaatg taccttcatg caatcacctc tgtgcatgtg ttggataaag
    48181 acaatccaca cgtgccactt tttacggaaa actagattag tatgatgaac tgtgtaaaat
    48241 agaaggttaa caaaaaagcg agtaaacgaa tgtcctgtca tttaggtttt cgtttactcg
    48301 ctttttgatg agattttact gctgtcctag caaaaggtga ggatgaggtc gtatatcaca
    48361 tagaggtttt ctgttaagcc ttatttgtta ctaaagaaga atggtggtgt gtaatgacta
    48421 agggtctcgt aacaagcctt ggcttgctca ttgtcttcac agacaatcaa gcaagtatca
    48481 tcaccacaga tcgttgctac aatttctgga atttgcatgg catctaaaat ggagccaaag
    48541 gattgggcta gtccaggtaa cgtttttaaa ataatttgat gttgaactat ctttaacatg
    48601 accaaagcgt cttccatgta aaaacgaaga cgatgttccc agcgggtttg tgaaatggct
    48661 aacgcttcat agtgtgtgtc gtttccagaa gttactttga ccaggttcaa ttccttcatg
    48721 tcacgtgata gggtagcctg agtgatcgtg atgccatttt tttgcaaccg ttcttgtaat
    48781 tcttgctgtg tatgtatagt tgtctcagag atgagggaac gtatgagttg gtgacgcgtc
    48841 tctttcttat tcattgttat aatcttcctt taacgtaatt gataacaatc cgagtatagc
    48901 aaaaagagga gaaggtgtaa agtttttgat gaaccgctta caaaatggct tttttatggt
    48961 aaaataaaga tgatgtttag aaaaaggaga tttgtgtgat tcgaagagaa gattatcaat
    49021 accttagaaa actaaacgat tttcgctact tttctattga acaatttgac aaaattgtag
    49081 ggcagatgga attccgaaaa gctaaaaagg accatatcct tttttttgag ggagataaaa
    49141 gagataagct ttttctagtg acctctggtt atttcaaggt ggagcagtcc gatcaatcag
    49201 gaaccttcat gtatacggat ttcatcagac acggtaccat ttttccttac ggtggcctct
    49261 ttacagatga ttattaccat ttttcagtgg tagccatgac agacgtgact tatttttact
    49321 ttccagtcga tttatttgaa gattattcgc ttgaaaatcg tctacaaatg aaacacttat
    49381 atagtaagat gtctaaactg ctcgagttac atgagttgag ggttcgaaat ttgattacat
    49441 caagtgctag ttctcgtgtg attcaatctc tggcgatttt gctggttgaa atgggtaaag
    49501 acagtgatac cttacctttt caattaacaa caacagatat tgctcaaata agtgggacga
    49561 caagagaaac tgttagccat gtgcttaggg atttgaagaa gcaagaattg attaccataa
    49621 aaggtaagta tttgacttat ctagataaag actatttttt acaat
//
LOCUS       DAUNLR010000006        46091 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUNLR010000006 DAUNLR010000000
VERSION     DAUNLR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46091
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.006"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            18..98
                     /locus_tag="VLL59_000352"
     tRNA            18..98
                     /locus_tag="VLL59_000352"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VLL59_000353"
     tRNA            105..175
                     /locus_tag="VLL59_000353"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VLL59_000354"
     tRNA            187..259
                     /locus_tag="VLL59_000354"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VLL59_000355"
     tRNA            268..339
                     /locus_tag="VLL59_000355"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VLL59_000356"
     tRNA            359..442
                     /locus_tag="VLL59_000356"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            702..887
                     /locus_tag="VLL59_000357"
     CDS             702..887
                     /locus_tag="VLL59_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508507.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWPEP"
     gene            1525..1833
                     /locus_tag="VLL59_000358"
     CDS             1525..1833
                     /locus_tag="VLL59_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HER6508508.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSDVPYCLLSGCAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            1888..2100
                     /locus_tag="VLL59_000359"
     CDS             1888..2100
                     /locus_tag="VLL59_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HER6508509.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            2210..2653
                     /locus_tag="VLL59_000360"
     CDS             2210..2653
                     /locus_tag="VLL59_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HER6508510.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2657..3376
                     /locus_tag="VLL59_000361"
     CDS             2657..3376
                     /locus_tag="VLL59_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HER6508511.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEVETDDEKGGHGHA"
     gene            3369..4184
                     /locus_tag="VLL59_000362"
     CDS             3369..4184
                     /locus_tag="VLL59_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HER6508512.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVFGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4224..4607)
                     /locus_tag="VLL59_000363"
     CDS             complement(4224..4607)
                     /locus_tag="VLL59_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HER6508513.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWEGITINQENWDLAPFLKHL"
     gene            complement(4658..5914)
                     /locus_tag="VLL59_000364"
     CDS             complement(4658..5914)
                     /locus_tag="VLL59_000364"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HER6508514.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEVYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6006..8318
                     /locus_tag="VLL59_000365"
     CDS             6006..8318
                     /locus_tag="VLL59_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HER6508515.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8582..12148
                     /gene="rpoB"
                     /locus_tag="VLL59_000366"
     CDS             8582..12148
                     /gene="rpoB"
                     /locus_tag="VLL59_000366"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HER6508516.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGTVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12239..15880
                     /gene="rpoC"
                     /locus_tag="VLL59_000367"
     CDS             12239..15880
                     /gene="rpoC"
                     /locus_tag="VLL59_000367"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HER6508517.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16032..16397
                     /locus_tag="VLL59_000368"
     CDS             16032..16397
                     /locus_tag="VLL59_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HER6508518.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVTYLCKLNL"
     gene            16490..17428
                     /gene="tadA"
                     /locus_tag="VLL59_000369"
     CDS             16490..17428
                     /gene="tadA"
                     /locus_tag="VLL59_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HER6508519.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYARLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLFEAGHLNPKQAKLEKII"
     gene            17412..18398
                     /locus_tag="VLL59_000370"
     CDS             17412..18398
                     /locus_tag="VLL59_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HER6508520.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFVEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18400..18726
                     /locus_tag="VLL59_000371"
     CDS             18400..18726
                     /locus_tag="VLL59_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HER6508521.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18701..19129
                     /locus_tag="VLL59_000372"
     CDS             18701..19129
                     /locus_tag="VLL59_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HER6508522.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19134..19370
                     /locus_tag="VLL59_000373"
     CDS             19134..19370
                     /locus_tag="VLL59_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HER6508523.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEITLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19363..19797
                     /locus_tag="VLL59_000374"
     CDS             19363..19797
                     /locus_tag="VLL59_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HER6508524.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19781..20107
                     /locus_tag="VLL59_000375"
     CDS             19781..20107
                     /locus_tag="VLL59_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HER6508525.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20205..21158
                     /locus_tag="VLL59_000376"
     CDS             20205..21158
                     /locus_tag="VLL59_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HER6508526.1"
                     /translation="MTFEKIEEAYQLLLENCQLIKNDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21217..22413
                     /locus_tag="VLL59_000377"
     CDS             21217..22413
                     /locus_tag="VLL59_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HER6508527.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22600..22842
                     /locus_tag="VLL59_000378"
     CDS             22600..22842
                     /locus_tag="VLL59_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508528.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLALIFAYLYLIIRSLVAKKM"
     gene            complement(22991..23761)
                     /locus_tag="VLL59_000379"
     CDS             complement(22991..23761)
                     /locus_tag="VLL59_000379"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HER6508529.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLA
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23809..24876)
                     /gene="pepA"
                     /locus_tag="VLL59_000380"
     CDS             complement(23809..24876)
                     /gene="pepA"
                     /locus_tag="VLL59_000380"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HER6508530.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLCGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEEAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            25332..25625
                     /locus_tag="VLL59_000381"
     CDS             25332..25625
                     /locus_tag="VLL59_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HER6508531.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25622..25939
                     /locus_tag="VLL59_000382"
     CDS             25622..25939
                     /locus_tag="VLL59_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HER6508532.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25957..26583
                     /locus_tag="VLL59_000383"
     CDS             25957..26583
                     /locus_tag="VLL59_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HER6508533.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPIVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            26735..27130
                     /locus_tag="VLL59_000384"
     CDS             26735..27130
                     /locus_tag="VLL59_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HER6508534.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27390..28031)
                     /locus_tag="VLL59_000385"
     CDS             complement(27390..28031)
                     /locus_tag="VLL59_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HER6508535.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28051..29028)
                     /gene="dusB"
                     /locus_tag="VLL59_000386"
     CDS             complement(28051..29028)
                     /gene="dusB"
                     /locus_tag="VLL59_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HER6508536.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAIE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(29015..29887)
                     /gene="hslO"
                     /locus_tag="VLL59_000387"
     CDS             complement(29015..29887)
                     /gene="hslO"
                     /locus_tag="VLL59_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HER6508537.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGTPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLFEEPLSFQCDCSRERFEAALITLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIINDKA"
     gene            complement(30034..31527)
                     /gene="rofA"
                     /locus_tag="VLL59_000388"
     CDS             complement(30034..31527)
                     /gene="rofA"
                     /locus_tag="VLL59_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HER6508538.1"
                     /translation="MIEKYLESSIESKCQLIILFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSHDIIETYCQLIFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPSLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRDLNHKHFHLFCHYVEQSLRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHPYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
     gene            31758..33281
                     /gene="sfbI"
                     /locus_tag="VLL59_000389"
     CDS             31758..33281
                     /gene="sfbI"
                     /locus_tag="VLL59_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein SfbI"
                     /protein_id="HER6508539.1"
                     /translation="MVSSYMFLRGEKMNNKIFLNKEAGFLAHTKRKRRFAVTLVGVFF
                     MLLACAGAIGFGQVAYAADERTVPNFKSPDPDYPWYGYDAYTGAFLRYHDLRVNLNGS
                     RSYQVYCFNIKKNYPRPFTSSDKKWYKRLEGTAETFKVHAMAPRVGGEELTKKLRSVM
                     YNGYPNDGNNIMKGLEPSNAIEVTQYAVWYYSDKSQYEIETLWKSEAKEGKISESQVT
                     LMREALRKLISSDEDLVKQVPSNFKLSTFESSDKSYQNLLSAEFVPDDPPKPGDTSEH
                     NPKTPELDGSPIPEDPKHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALPPLMPELDG
                     QEVPEKPSVDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQNPVDIDKKLPNE
                     TGFSGNMVETEDTKEPEVLMGGQSESVEFTKDTQTGMSGFSETVTIVEDTRPKLVFHF
                     DNNEPKVEENREKPTKNITPILPATGDIGNVLAFLGILILSVLSIFSLLKNKQNNKV"
     gene            33569..34417
                     /locus_tag="VLL59_000390"
     CDS             33569..34417
                     /locus_tag="VLL59_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HER6508540.1"
                     /translation="MTERLKNLGILLLFLLGTAIFLYPTLSSQWNAYRDRQLLSTYHK
                     QVTQKKPSEMEEVWQKAKAYNARLGIQPVPDAFSFRDGIHDKNYESLLQIENNDIMGY
                     VEVPSIKVTLPIYHYTTDEVLTKGAGHLVGSALPVGGDGTHTVISAHRGLPSAEMFTN
                     LNLVKRGDTFYFRVLNKVLAYKVDQILTVEPDQVTSLSGVMGKDYATLVTCTPYGVNT
                     KRLLVRGHRIAYHYKKYQQAKKAMKLVDKSRMWTEVVCAAFGVVIAIILVFMYSKMTD
                     KKVIKN"
     gene            34703..36943
                     /locus_tag="VLL59_000391"
     CDS             34703..36943
                     /locus_tag="VLL59_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus ancillary protein 1"
                     /protein_id="HER6508541.1"
                     /translation="MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMLLVLIGFEGKV
                     RAAHELVEVPVPIFHNPDPQSDYQWYGYEAYTGGYPKYDLFKTYYHDLRVNLHGSKSY
                     QVYCFNVHKHYPRSSQSFDRKWYKKLDGTAENFDSLAMEPRVRKEELTKKLRAVMYNA
                     YPNDANGIMKDLEPLNAIKVTQEAVWYYSDSAQINPDESFKTEAQSNGINDQQLGLMR
                     KALKELIDPNLGSKYSNKTPSGYRLNVFESHDKTFQNLLSAEYVPDTPPKPGEEPPAK
                     TEKTSVIIRKYAEGDYSKLLEGATLRLTGEDIPDFQEKVFQSNGTGEKIELSNGTYTL
                     TETSSPDGYKIAEPIKFRVVNKKVFIVQKDGSQVENPNKEVGSPYTIEAYNDFDEFGL
                     LSTQNYAKFYYGKNYDGSSQIVYCFNANLKSPPDSEDHGATINPDFTTGDIRYSHIAG
                     SDLIKYANTARDEDPQLFLKHVKKVIENGYHKKGQAIPYNGLTEAQFRAATQLAIYYF
                     TDSVDLTKDRLKDFHGFGDMNDQTLGVAKKIVEYALSDEDSKLTNLDFFVPNNSKYQS
                     LIGTEYHPDDLVDVIRMEDKKQEVIPVTHSLTVKKTVVGELGDKTKGFQFELELKDKT
                     GQPIVDALKTNNQDLVAKDEKYSFNLKHGDTIRIEGLPTGYSYTLKETEAKDYIVTVD
                     NKVSQEAQSASENVTADKEVTFENRKDLVPPTGLTTDGAIYLWLLFLVPFGLLVWLFG
                     RKGTKK"
     gene            36940..37461
                     /gene="lepB"
                     /locus_tag="VLL59_000392"
     CDS             36940..37461
                     /gene="lepB"
                     /locus_tag="VLL59_000392"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HER6508542.1"
                     /translation="MTNYLNRLNENPLLKAFIRLVLKISIIGFLGYILFQYVFGVMIV
                     NTNQMSPAVSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVNFTQEGG
                     LLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALPINQI
                     KGKISTLLRVRGI"
     gene            37483..38538
                     /locus_tag="VLL59_000393"
     CDS             37483..38538
                     /locus_tag="VLL59_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QVPTGV class sortase B protein-sorting
                     domain-containing protein"
                     /protein_id="HER6508543.1"
                     /translation="MKKNKLLLASTILATALGMNNLASAEVNYVKSGVIDGAKLEIHK
                     TIKNYDDDKVLMPNVIFKFNIKPDDSVVAGKKEEKSGLDIKPGIVDGLETSKEVSYTN
                     SDKPNSKDKYTYFDFSQVKFTNVGIYRYIVEEVQDTVSGIHYDSQKWYIDVYVVEGDN
                     GFVPKYIVSSKALETKEPVLFSNSFDTTSLVVKKEVTGNTGDKTKNFKFQLLLKENAY
                     FSAGQKVSVTITSEKASEVTTATIGQPLIFELKHNEQLKLDKLPVGITYQIDETSKNS
                     DSYTTTATIQEGEQSQNSYVLNSDKETDKSPDIITVTNKRDTQVPTGVVGTLAPFAVL
                     SIVAIGGVIYITKRKKA"
     gene            38554..39279
                     /gene="srtB"
                     /locus_tag="VLL59_000394"
     CDS             38554..39279
                     /gene="srtB"
                     /locus_tag="VLL59_000394"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HER6508544.1"
                     /translation="MMMTIVQVINKAIDTLILIFCLVVLFLAGFGLWDSYHLYQQADA
                     SNFKKFKTAQQQPKFEDLLALNEDVIGWLNIPGTHIDYPLVQGKTNLEYINKAVDGSV
                     AMSGSLFLDTRNHNDFTDDYSLIYGHHMAGNAMFGEIPKFLKKDFFNKHNKAIIETKE
                     RKKLTVTIFACLKTDAFDQLVFNPNAITNQDQQRQLVDYISKRSKQFKPVKLKYHTKF
                     VAFSTCENFSTDNRVIVVGTIQE"
     gene            39296..39883
                     /locus_tag="VLL59_000395"
     CDS             39296..39883
                     /locus_tag="VLL59_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HER6508545.1"
                     /translation="MRKYWKMLFSVVMILTMLAFNQTVLAKDSTVQTSISVENVLERA
                     GDSTPFSIALESIDAMKTIEEITIAGSGKASFSPLTFTTVGQYTYRVYQKPSQNKDYQ
                     ADTTVFDVLVYVTYDEDGTLVAKVISRRAGDEEKSAITFKPKRLVKPIPPRQPDIPKT
                     PLPLAGEVKSLLGILSIVLLGLLVLLYVKKLKSRL"
     gene            complement(40042..41247)
                     /locus_tag="VLL59_000396"
     CDS             complement(40042..41247)
                     /locus_tag="VLL59_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HER6508546.1"
                     /translation="MVIFDLKHVQTLHSLSQLPISVMSQDKALIQVYGNDDYLLCYYQ
                     FLKHLAIPQAAQDVIFYEGLFEESFMIFPLCHYIIAIGPFYPYSLNKDYQEQLANNFL
                     KHSSHRSKEELLSYMALVPHFPINNVRNLLIAIDAFFDTQFETTCQQTIHQLLQHSKQ
                     MTADPDIIHRLKHISKASSQLPPVLEHLNHIMDLVKLGNPQLLKQEINRIPLSSITSS
                     SISALRAEKNLTVIYLTRLLEFSFVENTDVAKHYSLVKYYMALNEEASDLLKVLRIRC
                     AAIIHFSESLTNKSISDKRQMYNSVLHYVDSHLYSKLKVSDIAKRLYVSESHLRSVFK
                     KYSNVSLQHYILSTKIKEAQLLLKRGIPVGEVAKSLYFYDTTHFHKIFKKYTGISSKD
                     YLAKYRDNI"
     gene            41632..45126
                     /locus_tag="VLL59_000397"
     CDS             41632..45126
                     /locus_tag="VLL59_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HER6508547.1"
                     /translation="MTQKNSYKLSFLLSLTGFILGLLLVFIGLSGVSVGHAETRNGAN
                     KQGSFEIKKVDQNNKPLSGATFSLTPKDGKGKPVQTFTSSEEGIIDAPNLQPGTYTLK
                     EDKAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISKAGSKDVSSSLQLEKSTMSV
                     FSKYGGTEVTSGAADFYRNHAAYFKMSFELKQKDKSETINPGDTFVLQLDKRLNPKGI
                     SQDIPKIIYDSENSPLAIGKYDAKTHQLTYTFTNYIAGLDKVQLSAELSLFLENKVVL
                     ENQTISDFKSTIGDQEIKYGGTVNVLYGNASGQDNNYVTNGLSNVGGSIESYNTQTGD
                     FTWYVYVNPNRTNIPYATMNLWGFGRLVKSNNSTSKSEDSATSSAQLEKVEIYEVKED
                     YTLPTSYGVDLTKLNLRKDLEAKLPQDSTQNSNKRLRIDFGDKLQNKAFVVKITGKTD
                     QSGKPLVVQSNLASFNNETAVTYGNPVNNVYFQNEIALSPSKGSGSGTSEFTKPSITV
                     ANLKRVAQLRFKKMSTDNVPLPEAAFELRSSNGNSQKVEAKSNTQGEVHFKDLTSGTY
                     DLYEKQAPKGYQQVTEKLATVTVDTTKPAEEMVTWGSPHSSVKVEDSKEVTIVNHKET
                     LTFSGKKIWENDRPDQRPAKIQVQLLQNGQKMSDKVQEVTKDNDWSYHFKDLPKYDDK
                     NQEYKYSVEEVKVPDGYKVSYLGNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGSKI
                     IDEDTLTSFKGKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEFKN
                     LKKYNGTGNDIIYSVKEVTVPTGYDVTYSANDIINTKREVITQQGPKLEIEETLPLES
                     GASGGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFSKRDIDGKELAGATM
                     ELRDSSGKTISTWISDGQVKDFYLMPGKYTFVETAAPDGYEIATAITFTVNEQGQVTV
                     NGKATKGDAHIVMVDAYKPTKGSGQVIDIEEKLPDEQGHSGSTTEIEDSKSSDLIIGG
                     QGEVVDTTEDTQSGMTGHSGSTTEIEDSKSSDVIIGGQGQVVETTEDTQTGMHGDSGC
                     KTEVEDTKLVQSFHFDNKEPESNSEIPKKDKPKSNTSLPATGEKQHNMFFWMVTSCSL
                     ISSVFVISLKSKKRLSSC"
     gene            complement(45394..46059)
                     /locus_tag="VLL59_000398"
     CDS             complement(45394..46059)
                     /locus_tag="VLL59_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508548.1"
                     /translation="MKRCNKYLFTSLLAVSMLFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKTLVDNNNSIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPTEITYEHYY
                     WDGTVDSKTRSNTQWHYNWENQKTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEEDYKNKWDKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
BASE COUNT        14426 a         8050 c         9746 g        13869 t
ORIGIN      
        1 aaaatttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tgtaaacctt gttttttgtt
      481 ttgatcttaa gctgtagcta cgtagtacaa tctcttatat tactgataag gtctatttaa
      541 tgcgcaagat ttgtggtatg atgaatatga ttgagtattg atgctttatg ggattaccgg
      601 taaggttttg aaaaaggttt gtcactacta ggtgcttttt tagctataga aagacagtta
      661 tggattgatg tattgtaact aatgttggag gttaatggtg gttgagtttt gagatattta
      721 cactgataat cgggtggaaa ctggttgggt atcgggtaat ggagtgtggt tcttcgttta
      781 agcaaggaga ttatcgtttg gtggttcata tttgcttgtt aaatgttagg gatgagatgc
      841 tgagtcagca aggccatgaa gataaagctg actggccaga gccttgagat gtgacgtttg
      901 gtggaagtcc tttttggtga gatggcacag catatagtaa tattagatcc tgaggaagaa
      961 ttgggacttt cattaggcct gactggggta tgacctcact ttacaattca tttcgatgat
     1021 gggtttgatg atatgttttt agttcaggac tttgtagagt tggagaattt ggttctttat
     1081 gaggaagaag tgcaggtaat tcgttgagcc agtcgtgaag atattttagg tatgattgat
     1141 gaaggttcgt tcattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggc
     1201 caatataaag tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt
     1261 atatttgata gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga
     1321 gcttctgcaa aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac
     1381 gatttatcga tggtcatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata
     1441 gatgacaata agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat
     1501 gatgtttata agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc
     1561 gtttacttgg aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct
     1621 gttactatca gagcattaaa tcagttatgg ctccttactc ttagccgaaa agatatgatg
     1681 gatattggta taccgattgg tagtgatgtg ccttattgct tgctttcagg ttgtgcccaa
     1741 gtcactggta aaggtgaagt ggtttgtcgc attttggggc tgttatcgtc ttgggtggtt
     1801 ttggttaaac cagattttgg tatctcgact tgaacaattt ttctagatat taattgtaaa
     1861 accatttcaa gagtgtctac tactcatttg gttgcggcga ttgaagcggg taactataat
     1921 gatgggatat tgactgaaat gaacaatttg ctggaagata ttttcattgc caagcgaccc
     1981 tttattcaaa aaataaaaga gaaaacactg caagctggtg ctgctactac tttgatgaca
     2041 ggaagtggac cgactgtttt tgctttgtgc cagaccgaaa aacaaactat aatagtttaa
     2101 aaggactttg caaggaagtt tttaaggtga gaatgttgta atattttgtt gggattgctt
     2161 ctttggaagc ttcatgttat aattaactgg ttaatgaaag aggagattta tggggacttt
     2221 agaaaaaaaa cttgataact tagtaaatac tattttatta aaagcagaaa atcagcatga
     2281 gttattattt ggagcttgtc aaagtgacgt taagcttact aatacgcaag aacatatttt
     2341 aatgttacta tctcagcaac gtctcactaa tacagatttg gctaaggcat taaatattag
     2401 tcaggcggca gtaactaagg ctatcaagag tttggtcaaa caagacatgc tagcaggaac
     2461 taaggatacg gttgatgcta gggtgactta ttttgaatta accgagttag ctaagcctat
     2521 tgcgtcagaa catacccatc atcatgatga aaccttaaat gtttacaacc gtttattaca
     2581 aaaattctcc gcgaaagaat tagagattgt agataagttt gtaacagttt ttgctgagga
     2641 attagaaggg taatccatga gatacatatc agtgaaaaat ctctcctttc aatatgaaag
     2701 tgagccagtt ttagaaggga tcacttatca tttagatagt ggagaatttg tcaccatgac
     2761 cggtgaaaat ggcgctgcaa agtcaacctt aataaaagca accttaggaa ttttacaacc
     2821 aaaggctgga cgagttacta ttgctaaaaa aaataaagac ggtaaacaat taaggattgc
     2881 ttacttgccg cagcaagtag ctagctttaa cgctggtttt ccatccaccg tttacgagtt
     2941 tgtcaaatca ggtcgctacc cacgtagtgg ttggtttaga catttgaaca aacacgatga
     3001 agagcatgtg caagcaagct tagaagcagt cggcatgtgg gaaaaccgtc ataagagaat
     3061 tggtagttta tcaggtggtc aaaaacaacg tgtggttatt gcccgtatgt ttgcttctga
     3121 ccctgatatt tttgtgctag acgagccaac aacgggaatg gatagcggta ctactgatac
     3181 cttttatgaa ctgatgcacc acagtgcaca tcaacatggg aaatccgttc tgatgattac
     3241 ccatgaccca gaagaagtga aggcttatgc tgatcggaac attcatttag tcagaaacca
     3301 aaaacttcct tggcgttgtt tcaacattca tgaagttgaa acagatgacg aaaaaggagg
     3361 tcatggtcat gcttgatatt ttatcctatg atttcatgca acgggcggta atggcggtag
     3421 ttgccattag tatttttgct ccgattttag gtattttcct tattttacgt cgtcaaagtt
     3481 tgatgagcga tacccttagt catgtttctt tggctggggt agcgcttggg gtagtctttg
     3541 gtatttcacc aaccatcact actattattg ttgtggtttt agctgctatt ttgttagaat
     3601 acctgcgtgt agtttacaaa cactacatgg agatttcaac ggcgattttg atgtcacttg
     3661 gcttggccct atctctgatt attatgagta agtcgcatag ttcatcaagc atgagtttag
     3721 aacaatacct ttttggatcg atcatcacga ttagtatgga acaagttgtc gccttgtttg
     3781 ctattgctgc gattatttta atcttgaccg ttctcttcat tagaccgatg tacattctga
     3841 cctttgatga agatactgct tttgtagatg gtttgcccgt tcgcttgatg tctgttctat
     3901 tcaatatcgt cactggggtt gctattgctt tgaccattcc agcagcagga gcacttttgg
     3961 tttctaccat tatggtcttg ccagcaagta tcgcaatgag attgggtaaa aactttaaaa
     4021 cagttatctt actgggaatt gtcatcggtt ttagcggtat gttatctggt attttcttat
     4081 cttatttctt tgaaacgcca gctagtgcca ctattaccat gattttcatt agtattttcc
     4141 tcttagttag tctaggtgga atgcttaaaa aacggttatt ttaataagaa aaatcctcac
     4201 atgtttaaca tgtgaggatt tatttataaa tgctttaaaa agggggcaag gtcccaattt
     4261 tcttgattaa tggtgatgcc ctcccaaaag ctatcattag ttaaacgagg aatcaaatga
     4321 aggtgaaaat gagtcccctc atccatcaac tccttgtcat tgctgacgct agtgacgcct
     4381 gaaatgggaa ggtgctgctc tagcttagca actagagcgg cttgtaagtc gatgagatca
     4441 tagcgcactt cctttggtag ttgtgttaga ctagtgtaat ggtctttgga aatcagtaaa
     4501 aggtgcccct tttggatagg atcaatatca aaaacaacct tgaaatattg actttgagtc
     4561 agtagctgat ttgctttgag ctgatggcaa aagatacatt ctgtcatagg tacatctcct
     4621 tatgaaaaaa cgagccagag ctcgtttaat cggttatcta gtaagtgaga acagcgtatt
     4681 ttttcttgcc gcggcgaata acggttaatt gatcatcaat tttatcatca ttacttaatt
     4741 ggtaatctaa atcttgaacg cggtctccgt taatgtagat tgctccattt tgcacgtctt
     4801 cacgcgcttg gcgttttgat ggggaaatac ctgcggtgac aagcatgtca acaaggttaa
     4861 ggctgtcttc tgattgaacg tgataatttg gtacattgct caatccttgt tttaattcat
     4921 tagcagaaag atttttgatg tttccagcaa ataactgctc ggtaatgtta agagcttgtt
     4981 tataaacttc ttcgccatga accaaggtaa ccacttcgcg tgccaaggtt ttttgagcga
     5041 gacgctcgtg acgagcggca ttaaattgag tttcaatttc tgcaatctca tctagagata
     5101 agaaggtgaa gattttcaag aaacgcactg catcatcatc catgacattt aaccagaatt
     5161 ggtacatctc gtaaggagac gtcttatcgg catcaagcca gacggcatta ccttctgatt
     5221 taccgaattt tttcccggtt gagtcagtga tgagtggtac agtcatgacg tgcccagttt
     5281 tatcagcctt tttgcggagc aattcagtac cagctgtcat attgccccac tggtcagagc
     5341 cgccaatttg taaggttaca ttatgcttgt cattgagttc gtagaagtcg tagccctgca
     5401 tgatttggta agcaaactca gtgtaagaaa tgcctgtttc aatgcgtttt ttaacagagt
     5461 ctttactcat catgtagtta acggtgaagt atttaccgac atcacggagg aagtcaataa
     5521 agctgatttg cgagaaccag tcgtagttgt tgacaagctc tgctttatta tcaccatttt
     5581 caaaatcaag gaaagtagac aactgccctt taatcttgtc actccactcc aaaactgttt
     5641 ctttggtttg aaggctgcgc tctgcatctt taaaggaagg atcaccaatt aaacctgtgg
     5701 caccacccac aagagcgtaa ggtttgtgcc ctgctagttg caagcgacga gatgttaaga
     5761 tagccactag atggcccaga tgaaggctgt cagcggttgg atcataaccg gtataatagg
     5821 atacttgccc ttctgttaat gctttgacaa gggcttgttc atcagttgtt tgaaagacca
     5881 agccacgagc tttgagttct tcaaaaatat tcataggctt tctccatttt cattatagtt
     5941 tcgaatcatt atatcaaaaa acgctactgc tatgcaagct ttatcaaagt ttggtataat
     6001 gataaatgag gtattttatg gtgaaatgga acacgaaaca aaagcgtata agtcatcaaa
     6061 gattaggtct cttggatttg gggccggtgc tattacgtac gttgagacta ctgtctaact
     6121 ttttttatat tgttatcttc ctttttggaa tgatgggatt tggtatggca tttgggtatt
     6181 tggctagtca gattgaatct gttaaggtac caagtaaaga aagtttagtc aaacaagttg
     6241 aatcattaac gatgatttcg caaatgaact attctgataa tagtttaatt tctactttag
     6301 atacggattt acttcgaaca ccagtagcta atgatgcgat ttcagagaat atcaaaaaag
     6361 ctattgtatc aacagaagac gaacattttc aagaacataa aggtgtcgtg ccaaaagctg
     6421 tttttcgggc aacattggct tctgtattgg gatttggaga agctagtgga ggttcgacct
     6481 taacacagca attggtcaaa caacaagttt tgggagatga tcccacattt aagcgcaagt
     6541 ctaaggagat cgtttacgct cttgccttag agcgttatat gtccaaagac aatatcttat
     6601 gtgattatct taatgtttca ccttttggtc gtaacaacaa gggccaaaat attgctggtg
     6661 ttgaagaagc tgcgcgtggc atttttggcg tttctgccaa agatttaacg gtgccacagg
     6721 cagcattttt ggcggggctt ccgcagagtc ctattgttta ctctccctat ttgtcaacgg
     6781 gacaactgaa gtcagaaaag gacatggctt atggcatcaa gcgtcagcaa aatgttctct
     6841 ataacatgta ccgtacaggt gttctgtcta aaaaagaata cgaggactat aaggcttatc
     6901 cgattcaaaa ggattttatt caaccgggaa gtgcaatagt aaataatcac gattaccttt
     6961 attacacggt gttagcggat gctaaaaaag ccatgtatag ctatttgatt aagcgagata
     7021 aggtgtctag tcgtgatttg aaaaatgacg agactaaggc tgcttatgaa gagagagcct
     7081 taacagaatt gcaacagggt ggctatacca tcaccacaac cattaataag cctatttaca
     7141 atgcgatgca gacagcggca gctcagtttg gtggcctgtt agatgatggc actggtacag
     7201 ttcaaatggg aaatgtcttg acagacaatg cgactggtgc cgtgttaggt tttgttggtg
     7261 gtagagatta tgctctgaat caaaataatc atgctttcaa tacagttaga tcgccaggtt
     7321 ctagcattaa accgataatc gcttatggtc ctgctattga tcaaggttta atggggagtg
     7381 ctagcgtttt gtctaattac ccaacaactt actcgagtgg ccaaaaaatc atgcatgctg
     7441 atagtgaagg aacagccatg atgccacttc aagaggccct aaatacttct tggaatatcc
     7501 cagctttttg gacacagaaa ttactgcgtg aaaaaggggt cgatgtcgaa aattatatga
     7561 caaaaatggg ttataagatt gcagactact cgattgaaag tttacctcta gggggcggta
     7621 ttgaagtctc ggttgctcaa caaaccaatg cttaccaaat gctttcaaac aatggcttat
     7681 atcaaaagca atatattgta gataagatta ctgctagcga tggtacagtc gtttacaaac
     7741 atgaaaataa gccaattcgt attttttctg cagcaacagc tacgatttta caagaattgt
     7801 tgagaggtcc gattacttca ggcgctacga ctactttcaa gaaccgtttg gcggctatta
     7861 atccgtggct tgctaatgct gattggattg gtaagaccgg aacaactgag aattatacgg
     7921 atgtttggct agtcctgtct actccaaaag ttaccttagg cggttgggca ggacatgatg
     7981 acaatacctc attagcgcca ttaacaggat ataacaataa ttctaattac cttgcctatt
     8041 tagctaatgc cattaatcag gccgatccca atgttattgg agtagggcaa cgtttcaact
     8101 tagatccagg agtcattaag gcgaatgtct tgaagtcaac aggtttacaa ccaggaactg
     8161 ttaatgtcaa tggacatact ttttctgttg gtggagaaat gaccaccagt ctatggtccc
     8221 aaaaaggacc gggggctatg acttaccgat ttgctattgg tggcacggat gccgattatc
     8281 aaaaagcttg ggggaacttt gggttcagaa aaaattaggt tgccatttat cgataaaaag
     8341 ggtataatag caataactat ttgtcgtcca atctagctga aatattgtcc agttaggaag
     8401 aacagcagtt aaatcacact gataaagtca gatttagctg ctctttttgt gtctattttt
     8461 agaaaagata gggtttgtaa cctatattta aatattctaa aaattaacat ttagggcaaa
     8521 tgataactta gttgcgattt gctgaaacag caaagcttaa atagaagaag gagctaaaaa
     8581 cttggcagga catgaagttc gatacggaaa acaccgtaca cgtcgtagct tttcaagaat
     8641 caaagaagtt cttgatttac caaatttgat tgaaattcaa actgactcat tccaagattt
     8701 cctcgattca ggtttgaaag aagtatttga agatgtactt cctatttcaa actttacgga
     8761 tactatggaa cttgaatttg ttggttacga atttaaagaa cctaaatata cccttgaaga
     8821 agctcgtatc cacgatgcaa gttattctgc accaatcttt gttaccttcc gtttggtcaa
     8881 taaagaaact ggtgagatta aaactcaaga agtcttcttt ggtgatttcc caatcatgac
     8941 ggaaatgggt acctttatta tcaatggtgg tgaacgtatc atcgtttctc agttggtgcg
     9001 ttctccaggt gtttatttca acgataaagt tgataaaaac ggtaaagttg gttacggatc
     9061 aacagtgatt cctaaccgtg gggcttggtt ggaattagag actgactcaa aagacattgc
     9121 ctacactcgt attgaccgta cgcgtaagat tccattcaca accttggttc gtgcacttgg
     9181 attctcaggt gatgatgaaa ttgttgatat ctttggtgaa agcgaccttg ttcgtaatac
     9241 cattgaaaaa gacattcaca aaaatccaag tgattctcgt acagacgaag cccttaaaga
     9301 aatttacgag cgtcttcgtc caggtgagcc aaaaactgca gatagctctc gtagtctctt
     9361 gattgcgcgt ttctttgatg cacgtcgtta cgatttggct gcggttggtc gttacaaagt
     9421 gaacaaaaaa cttaatatca agactcgtct tttgaaccaa atcattgctg aaaaccttgt
     9481 ggatgctgaa actggcgaaa ttttggtaga agctggaact gagatgactc gtagcgtcat
     9541 cgaatccatc gaagaacacc ttgacggtga tttgaacaag tttgtttaca caccaaatga
     9601 ttacgctgtg gttactgaac cagttgtcct tcaaaagttc aaggttgtgt caccaattga
     9661 tcctgatcgt gtagtaacta ttgttggtaa tgccaatcca gatgataagg ttcgtgcatt
     9721 gacacctgct gacattttgg cagaaatgtc ttacttcttg aaccttgcag aaggtcttgg
     9781 aaaagttgac gatattgacc acttaggtaa ccgtcgtatc cgtgctgttg gtgaattgct
     9841 tgccaaccaa ttccgcatcg gtcttgctcg tatggagcgt aacgttcgtg agcgtatgtc
     9901 tgttcaagac aacgatgtgt taacaccaca acaaatcatc aatatccgtc ctgtcacagc
     9961 agctgtcaaa gaattcttcg gttcgtctca gttgtcacaa ttcatggacc aacacaaccc
    10021 attgtcagag ttgtctcaca aacgtcgttt atctgcctta ggacctggtg gtttgacacg
    10081 tgaccgtgct ggttatgagg ttcgtgacgt gcattacacg cactatggcc gtatgtgtcc
    10141 gattgaaaca cctgaaggac caaacattgg attgattaac aacttgtctt catttggaca
    10201 tcttaataaa tatggtttca ttcaaacacc ttaccgtaag gttgaccgtg cgactggtac
    10261 ggtaactaac gagattgttt ggttgactgc cgacgaagaa gacgaataca cagttgcaca
    10321 ggccaattcg aaactaaacg aagatggcac ttttgctgaa gaaatcgtca tgggtcgtca
    10381 ccaaggtaat aaccaagaat tttctgcaag tgttgttgat ttcgttgacg tttcccctaa
    10441 acaggtagtt gctgttgcga cagcatgtat tcctttcttg gaaaatgatg actccaaccg
    10501 tgctctcatg ggtgccaaca tgcaacgtca ggctgtgcca ttgattgatc caaaagcacc
    10561 atatgttggt actggtatgg aatatcaagc tgcccatgac tcaggcgctg cggtgattgc
    10621 tcagcacaat ggtaaagttg tcttttctga tgctgaaaaa gtggaaatcc gtcgtcaaga
    10681 tggctcactt gatgtttatc acattaccaa attccgtcgt tcaaactcag gaacagccta
    10741 taaccaacgc acccttgtta aagtaggaga cattgttgaa aaaggtgatt tcatcgctga
    10801 tgggccttct atggaaaatg gtgaaatggc tcttggacaa aacccagtcg ttgcttacat
    10861 gacttgggaa ggttataact ttgaggatgc tgttatcatg agtgagcgcc ttgtgaaaga
    10921 agatgtctac acatctgttc acttggaaga attcgaatct gaaacgcgtg atacaaaact
    10981 tggccctgaa gaaatcactc gggaaatccc aaatgttggt gaagaagccc tcaaagacct
    11041 tgacgaaatg ggcattatcc gtatcggtgc tgaggttaaa gaaggcgaca tcttagtagg
    11101 taaagtcaca cctaaaggtg aaaaagacct ttctgctgaa gaacgtttac ttcacgccat
    11161 ctttggggat aaatcgcgtg aagtgcgtga tacctcactt cgtgtccctc acggtggtga
    11221 tggtatcgtt cgtgatgtga aaatctttac acgcgctaac ggcgatgaat tgcaatcagg
    11281 tgttaatatg cttgtgcgtg tttacatcgc tcaaaaacgt aaaatcaagg tcggagataa
    11341 aatggccggt cgtcacggaa acaagggtgt cgtttcacgt attgtaccag ttgaagacat
    11401 gccatacctt ccagacggaa caccagttga catcatgttg aaccctcttg gggtgccatc
    11461 acggatgaat attggtcagg ttatggaact tcaccttggt atggctgctc gtaatcttgg
    11521 tattcacatt gcaacacctg tctttgacgg ggcttcatca gaagaccttt gggacactgt
    11581 tcgtgaagct ggtatggata gcgatgctaa gacggtcctt tatgatggtc gcaccggtga
    11641 accatttgac aaccgtgtat ccgttggtgt catgtatatg atcaaacttc accacatggt
    11701 tgatgataaa cttcatgccc gttctgtagg accatactca cttgttaccc aacagccact
    11761 tggtggtaaa gctcaatttg gtggacaacg ttttggtgag atggaggttt gggcccttga
    11821 agcttatggt gcatcaaatg ttcttcaaga aatcttgacc tacaagtcgg atgacgtcac
    11881 aggacgtttg aaagcctatg aagcgattac taaaggtaaa ccaattccaa aaccaggtgt
    11941 accagaatcc ttccgtgttc ttgtaaaaga attgcaatcg cttggtcttg atatgcgtgt
    12001 gcttgacgag gatgataatg aagtggaact tcgtgatctt gatgaaggtg aagacgatga
    12061 cattatgcat gttgacgatc tcgagaaggc acgtgaaaaa caagctcaag aaacccaaga
    12121 agtttctgaa acaactgacg aaaaataagc aatcaattct tattaaataa ttatttactg
    12181 gtctggggca aaggccccag gaactggtaa agtcatcaaa ggcagaaagg taaaactagt
    12241 ggttgacgta aatcgtttta aaagtatgca aatcacatta gcctcaccaa gtaaggtccg
    12301 ttcatggtct tatggtgaag ttaaaaaacc tgaaacaatc aactaccgta cattaaaacc
    12361 agaacgtgaa ggactctttg acgaagtcat ctttggtcca acaaaagact gggaatgtgc
    12421 gtgtggcaag tacaaacgta tccgttataa agggatcgtt tgtgaccgct gtggggttga
    12481 ggtaactcgt gctaaagtac gtcgtgaacg tatgggtcac attgagttaa aagctcctgt
    12541 atcacatatc tggtatttca aagggattcc atctcgtatg ggattgactc ttgatatgag
    12601 ccctcgtgcc cttgaagaag tgatctattt tgcggcttat gtggtcattg atccaaaaga
    12661 tacaccgctt gaaccaaaat cattattaac agaacgtgaa taccgtgaaa aactacaaga
    12721 gtatggtcat ggatcatttg tcgctaagat gggtgctgaa gccattcaag atctcttgaa
    12781 acgtgtggac ttggcagctg aaatcgctga attaaaagaa gagttgaaat ctgcttctgg
    12841 tcaaaaacgg attaaagcag ttcgtcgttt agacgtcctt gatgccttta acaaatctgg
    12901 aaataaacca gaatggatgg ttcttaacat cctgccggtt attccaccag atcttcgtcc
    12961 gatggttcaa ttggatggtg gtcgttttgc ggcatcagac ttgaatgact tgtaccgtcg
    13021 tgtgattaac cgtaataacc gtttggcacg tttgttagaa cttaatgccc ctggcatcat
    13081 tgttcaaaat gaaaaacgaa tgcttcaaga agccgttgat gctttgattg ataatggtcg
    13141 tcgtggtcgt ccaatcactg gaccaggaag tcgtccattg aaatcattga gccacatgct
    13201 taaaggtaaa caagggcgtt tccgtcaaaa cttgcttggt aaacgtgtag acttctctgg
    13261 acgttccgtt atcgctgttg gtccaaccct taaaatgtat caatgtggtg tcccacgtga
    13321 aatggctatc gagcttttta aaccatttgt aatgcgcgaa attgttgcca aagaatatgc
    13381 tggtaacgtt aaagccgcta aacgtatggt tgaacgtggc gacgaacgca tctgggatat
    13441 cttagaagaa gttatcaaag aacacccagt cctacttaac cgcgcaccga ctcttcacag
    13501 acttggtatt caggcttttg aaccggttct tattgacggt aaggcacttc gtcttcaccc
    13561 acttgtgtgt gaggcctaca atgccgactt cgatggagac caaatggcca tccacgtgcc
    13621 actttcagaa gaagcacaag ctgaagctcg tcttttgatg cttgctgcag agcacatctt
    13681 gaaccctaaa gatggtaaac cagttgttac cccatctcag gatatggttc ttggtaacta
    13741 ctatcttacg atggaagatg ctggtcgcga aggcgaaggc atgatcttca aggataaaga
    13801 cgaagctgtg atggcatatc gtaatggcta tgctcatctt catagtcgtg tgggtattgc
    13861 tgttgacagc atgccaaaca aaccttggaa agacagtcaa agacataaaa tcatggtgac
    13921 aactgttggt aagattctct ttaacgacat catgccagag gaccttcctt acctccaaga
    13981 gccaaacaat gccaacttga cagaaggaac acctgataaa tacttccttg aacctggtca
    14041 agacatccaa gaagtgattg acggcttaga catcaatgtg ccatttaaga agaaaaacct
    14101 cggtaacatc attgcggaaa ccttcaaacg tttccgtaca acagaaacat cagccttcct
    14161 tgaccgcttg aaagaccttg gttactacca ttcaaccctt gctggtttga cagtgggtat
    14221 cgctgacatt cctgttattg ataataaagc tgaaatcatt gatgctgctc accatcgtgt
    14281 tgaagaaatt aacaaagcct tccgtcgtgg tttgatgaca gatgatgacc gttatgttgc
    14341 cgttacaaca acatggcgtg aagctaaaga agcccttgaa aaacgtctga ttgaaacaca
    14401 agatcctaag aacccaatcg ttatgatgat ggactcaggt gcccgtggta acatctctaa
    14461 cttctcacag cttgccggta tgcgtggttt gatggctgct cctaacggac gcatcatgga
    14521 acttcctatc ttgtcaaact tccgtgaagg tttgagcgtt ttggaaatgt tcttctcaac
    14581 ccacggtgca cgtaaaggga tgaccgatac ggcccttaaa acagccgact caggttatct
    14641 tactcgtcgt ttggttgacg ttgcccaaga tgttatcatt cgtgaggacg attgtggcac
    14701 tgatcgtggt cttcttatcc gtgctattac agatggtaaa gaagttaccg aaacgcttga
    14761 agagcgtctt caaggtcgtt acacacgtaa atcagtcaaa caccctgaaa ctggtgaagt
    14821 cttgattggt gctgaccaat taatcactga agacatggct cgtaagattg ttgatgcagg
    14881 tgttgaagaa gtgaccattc gttctgtctt tacctgtgcg actcgtcatg gtgtctgccg
    14941 tcactgttat ggtatcaact tggcaactgg tgatgctgtt gaagtgggtg aagcagttgg
    15001 tactattgct gcccaatcta tcggtgagcc tggtactcag cttaccatgc gtaccttcca
    15061 cacgggtggt gtagcctcaa ataccgatat cacccagggt cttcctcgta ttcaagagat
    15121 ctttgaagca cgtaatccta aaggggaagc ggtcattact gaagtgaaag ggaatgtcgt
    15181 cgagattgaa gaagatgcgt caactcgtac caagaaagtc tacgttcaag gaaaaactgg
    15241 catgggcgaa tatgtcgtac catttacagc acgtatgaaa gttgaagttg gcgacgaagt
    15301 taatcgcgga gctgccctta cagaagggtc aattcaaccg aaacgtctcc ttgaagtgcg
    15361 tgataccttg tcagttgaaa cgtaccttct tgcagaagta caaaaggttt accgtagcca
    15421 aggggtagaa atcggagaca aacacgttga ggtaatggtt cgccaaatgc ttcgtaaagt
    15481 tcgtgtcatg gatccaggtg atacagacct ccttccaggt acacttatgg atatttctga
    15541 tttcacagat gctaacaaag atattgttat ctctggtggt attcctgcga catctcgtcc
    15601 tgttcttatg ggtattacta aggcttccct tgaaactaat tccttcttat cagctgcatc
    15661 cttccaagaa acaactcgtg ttcttacaga tgctgctatc cgtggtaaga aagaccactt
    15721 acttggtctt aaagaaaatg ttatcattgg taaaatcatt ccagctggta ctggtatggc
    15781 gcgctaccgt aacattgaac cacaagcgat gaatgagatt gaagtgattg atcatacaga
    15841 agtctcagca gaagccgttt ttacagcaga agcagaataa tctcatgaaa gagtccttag
    15901 gggctctttt ttgtctgagt ttgttggcag taaaaagcat tgacaatcag tcttagtccc
    15961 aatgagcaga tgtttttcaa aatacttatg atttagctat aataatgcat aagaggaata
    16021 ggtaatgtgt tatgtatcaa gtaattaaaa tgtatggtga ttgggagcct tggtggttca
    16081 tcgatggatg gcaagacgat attatagatg agcaacaatt tagtgactgg caagaagcgc
    16141 ttgattattt taatcaagaa tggcagcgca tgaaagctat ttttcctagt tatcatagcc
    16201 aaaagaattt gttagctact ttttgggaaa aagaagataa aagatggtgc gaggactgtg
    16261 acgaagattt gcagcagttt cattctcttt tactccttaa aaataaagat attgtaccaa
    16321 gcaataatta tatccctgaa tttgaacaac gaaatgattc accacaggta acttatcttt
    16381 gcaagttaaa cctttaagtg tttgttaaaa acaaaataag ttaaaagaaa atatcacttc
    16441 ttctgatatt ttcttttttt gtttacgaat aaatgagtaa ggaggaatta tggtacaagc
    16501 attagcaaaa gctattctag caaaagctga acaggttcag gcacaagata tttatatttt
    16561 gccaagagca gatcaatatg atcttttttt acgaatagga gatgaaagga gattagttga
    16621 tgtttatcag agcgatcgga tggctcctct tattagtcac tttaaatttg ttgcaggaat
    16681 gatagttggt gaaaagagac gttgtcaggt gggttcatgt gattataagc ttagtaaaga
    16741 taagcagtta tctttgcgct tatctagcgt gggtgattat cgcgggcaag aaagcttagt
    16801 gattcgtctg cttcatcatc aaaataaaag tgtacattat tggtttgatg gattgacaaa
    16861 agtagccaat caagttggcg gtagagggtt gtatttattt gcaggaccag ttgggtctgg
    16921 gaagacaacc ttgatgtacc agctgatttc gaattatcat caaaaagcac aggttattag
    16981 tatagaagat cctgtagaaa ttaaaaatca ccagatttta caattacaag tgaatgatga
    17041 tattggtatg acttatgaca atttgatcaa actgtcttta cgccatcgac cagatatttt
    17101 agttattggt gagattcgag atagtcaaac agcaagagcc gttattaggg ctagtctaac
    17161 aggtgccatg gttttttcaa cggttcacgc taaaagtatc tcgggtgttt atgcaagatt
    17221 gttagaactt ggtgtaacga aagcagaact gtctaattgc ttagcattaa ttgcttacca
    17281 aaggttactt aatggaggag cattgattga ctctactcaa aacgaatttg aatattattc
    17341 ctcatcgaac tggaatcaac aaattgatca gctttttgag gcaggacatc tcaatcccaa
    17401 gcaagctaag cttgaaaaaa ttatctagta aacatcagca taaattcatt caattactag
    17461 ctaatctttt atctacagga tttagcttcg tagaggttat tgctttttta aaaagaagcc
    17521 agttgcttca gctagattat gttcttaaaa tggaagagtc tttattaaaa ggacaaggct
    17581 tagcagatat gttgtcgggt ttaggttttt cagatgctat tcttactcaa attagtttag
    17641 ctgatagaca cggtaatatt gaaacaacat tagtagcgat tcaacattac ttgaaccaaa
    17701 tggcaaggat cagacgaaaa actgttgaag ttatcaccta tcctcttatt cttttacttt
    17761 ttctttttgt gatgatgcta gggttgagac gctatttagt ccctcaatta gaaactcaaa
    17821 atcagataac ttactttctt aaccattttc ctgccttctt tataggtttt tgctcaggtc
    17881 ttattttgtt gttcgggatg gtatggctac gatggcgatc tcaaagccgc ttgaaactct
    17941 atagtcggct aagccgttat ccttttttag gtaaactgtt aaaacaatac ttaactagtt
    18001 attatgctag agaatggggt acgttaatag gtcaaggtct tgatttgatg actattttag
    18061 acattatggc cattgagaaa tcctcactaa tgaaagaatt agctgaggac atcagaatga
    18121 gtctgcttga agggcaagcc tttcacatta aagtagctac ctaccctttt tttaaaaaag
    18181 aattaagttt aatgattgaa tacggtgaaa tcaaatcgaa actgggggct gagttggaaa
    18241 tctatgccca ggaaagctgg gaacaatttt ttagtcagct ttatcaagtg acacaactta
    18301 ttcaaccagc tattttttta gtagttgctg tgacaatcgt catgatttat gcggcaatcc
    18361 tattaccaat ttaccaaaat atgggaggta ttttttaaga tgattaatca atggaacaac
    18421 ttacgacaca agaagctaaa aggatttact cttctagaaa tgttattggt gattcttgtc
    18481 atcagtgttt tgatgctatt atttgtgcct aatttaagca agcaaaaaga cagggttaca
    18541 gaaacaggta atgccgctgt tgttaaatta gtggagaatc aagcagaact atatgaatta
    18601 tctcaaggct caaaaccaag tttgagccag ttaaaggcag atggtagtat cactgagaaa
    18661 caagaaaaag cttatcaaga ctattatgac aaacataaaa atgaaaaagc ccgtcttagc
    18721 aattaaagct tttactttgc ttgaaacttt actaagtttg tcagtgatga gtttcattat
    18781 attgggattg tctgtaccag tgacaaaaag ctatcaaaaa gtagaagagc atctgttttt
    18841 tagccatttt gaacatttgt atcgacatca gcaaaagtta gccatattac agcaaaaaca
    18901 gcgcgtcttg gatatttctt caacaaaaat tgttacagaa ggtaatagcc taacagttcc
    18961 taaatcaata acagtgaatc atccttatcg gttagttatt gatcagatgg gaggcaacca
    19021 ttccttagcc aaaattattt ttgacatgac tgatcgacgc tttaaatacc aattttatct
    19081 agggagtggg aattatcaaa aaacaagtca aagcttacat agcccttgaa agtatgattg
    19141 caacaggcat cctctttagt attgtcattc tcgtcttaag cagtttacag cagagtcagg
    19201 ctgctctaac gtactatcga aagcagcaag aaaagcttaa tctagccttg atggcagtac
    19261 aaactagaac taaagagata acattgaatg gttgtcatat tactatttta cgtacggata
    19321 gatacattag tattcacgat gacgaaggag aagtgatgaa gattgagtaa acaattaagt
    19381 aacataaaag cttttaccct tctagaggcg ttaatagcct tactcgtgat atcagggtct
    19441 ttattggttt atcaaggttt gacccaaacc ctccttaaac gtagccatta tctagcccgt
    19501 catgatcaag acaattggct cttattttct catcaattgc gagaggagtt aagtggagca
    19561 agattttaca aagtagctga taataaacta tacgttgaaa aaggaaagaa agtactagct
    19621 tttggccaat ttaaaagtca tgattttcga aaatcagcta gtaatggaaa agggtatcaa
    19681 cccatgttat ttggaatatc acgtagtcat attcacatag agcagtcaca gatttgcatt
    19741 actttaaagt ggaaaagtgg gttagaaagg actttttatt atgcctttca agactaatct
    19801 caaagcaggc attcttttgt atgctatgtt tatggctagt atttttttgc tggttttaca
    19861 ggtttacctt tctcaagtga cagctctaca caaggaatac caagctcaaa ctgactatgt
    19921 taaagcccga ctgatagcag aaatagttta tcaagatcat agatataaag cttctaatcc
    19981 tgtctttttt aaaggtggtc aagtcatttg tcgagagcga aaagagagat ggatgttaat
    20041 tgttaagtta gatcagcaac gacagtatca gtttgaatac cttaaaccca aacaatatag
    20101 tcaataaata gtattgttgt cataaatcct taaaatgatc caatatatag taattaaagg
    20161 tgacgcttct tttcatttca agtgtaattt ggtatgataa ggttatgact tttgaaaaaa
    20221 ttgaagaagc ttatcagctg ctcttagaga actgtcaact aattaaaaat gatctaaaaa
    20281 cacatatata cgatgccatt gttgaacaaa actcctttta tttaggggct gagggagcta
    20341 gtcctcaagt tgctcaaaat agtgataaac tgaaagcctt gtgcctgaca aaagaagaat
    20401 ggcgtaaggc ctaccagttt ctttttatta aggcagctca gacggagcaa ctccaagcca
    20461 accatcagtt cacaccagat gctattggct tcattctgct gtatcttttg gaacaattga
    20521 gtgataaaga tagcttagag gtacttgaga ttggaagtgg aacagggaac ctagcccaaa
    20581 cccttctcaa caacacgagc aagagccttg attatgtagg gattgaactt gatgatctct
    20641 tgattgatct gtcagccagt attgctgaaa taatggattc ttcagctcat tttattcaag
    20701 aagatgcggt aaggcctcaa ttactaaaag aaagtgacat tgtcatcagt gacttaccag
    20761 ttggttatta tcctaacgat gatattgcca aacggtacaa ggtggctagt tcagataagc
    20821 atacctatgc ccatcattta ttaatggaac agtctttaaa atacttgaaa aaagacggtt
    20881 ttgcgatttt tctggcacca gtcaatttat tgacgagccc tcagagccag ttattgaaac
    20941 agtggttaaa agattatgct caggtggtgg ccttgattac gctaccagat tctatttttg
    21001 gtcatccctc aaatgccaag tccattattg tcttacaaaa acaaacagac cacccaatgg
    21061 aaacctttgt ctatccaatt cgggatttga agcttgcaga gaatattcat gattttatgg
    21121 aaaatttcaa aaaatggaaa ctgagtaatg tcaattaatt gattttttgt tataataaaa
    21181 aagcatcaca gaaaacgatt tcaagagagg ttaaaaatgt caaagacaat tgcaattaat
    21241 gcaggtagtt ctagtttaaa atggcaactt tatcagatgc cagaagaagc agtgttagca
    21301 caaggaatta ttgagcgtat cggtctcaag gattctattt caacagttaa gtacgatggc
    21361 aaaaaagaag agcaaattct tgatattcac gatcatacag aagctgttaa aatcttattg
    21421 aacgatttga ttcactttgg aatcattgca gcttatgatg aaattacagg agttggacac
    21481 cgtgttgttg ctggtggtga acttttcaaa gaatccgttg tggttaatga caaagttctt
    21541 gaacagattg aagaattatc cgttttagct ccacttcaca atcctggagc ggcggcaggg
    21601 attcgtgcct tccgtgatat tttgccagat attaccagtg tttgtgtgtt tgacacgtca
    21661 tttcacacta gcatggcaaa gcatacttac ctttacccaa ttcctcaaaa atattatacg
    21721 gactacaagg ttcgtaaata tggggcgcat gggacaagtc ataaatatgt agcgcaagaa
    21781 gctgctaaaa tgcttggtcg tccattagaa gaattaaaac taattactgc tcatattgga
    21841 aatggtgtct caattacagc taattaccac ggtaaatcag ttgatacctc gatgggcttt
    21901 acaccacttg ctggtcctat gatgggaaca cgttctggtg acattgaccc agctatcatt
    21961 ccttatttaa ttgagcaaga cccagaatta aaagacgctg ctgacgttgt gaatatgtta
    22021 aacaaaaaat caggtcttag tggggtgtca ggcatttcta gtgatatgcg tgatatcgag
    22081 gctggtttac aagaagataa tccagatgct gttttagctt acaatatctt tattgatcgc
    22141 attaaaaaat gcattggtca atattttgct gttttgaatg gggcagatgc tttggtcttt
    22201 acagctggta tgggtgaaaa tgcaccattg atgcgtcaag acgttattgg tggcttaacg
    22261 tggttcggaa tggacattga tcctgagaaa aatgtttttg gataccgtgg tgatatttca
    22321 acaccggagt caaaagtgaa ggttcttgtt atctcaacag acgaagaatt gtgcatcgcg
    22381 cgtgacgttg aacgtttaaa aaatacaaaa taaaagagac taagtctcaa tagattaacc
    22441 aagtaaggca acactttact tggtttttta tgaggtttat ctgttagtta tggtgcctag
    22501 gtattagttc tgatcagtct ccttgctttt tgtaatcttg tgctaggcga tttggatgtc
    22561 agccttattt agaagttttt aattgcttca acgcttttct tgtatgtgtt tatagagccc
    22621 aatgatctaa aagactattt gataacggtt tatgatgagc gtaatcgtgc gattcgaaaa
    22681 cagacacaag tttactgctt ttacctgatg attgttctat ttgttgcctt attctttttc
    22741 ttcccttgct taaccattcg agaccttgtt tcttataagc tagctttgat ttttgcttac
    22801 ctttacttga ttatcagaag tctggtggct aagaaaatgt aggcactagg gaaaataaca
    22861 actaatagtc aaaaacctcc gtttgatacg agtcaggttc tttgttagat gacttgtcta
    22921 acggttgagt ttcctgtctg gtcaacggag gtgtttgtat tgttgtctga tttgtattgg
    22981 ggcacttatt ttacaagctt ttagccttat cgatggtttt gtcaatggca gagctgacag
    23041 tagttgtgag gccaaggcgt tctaactcca ttagaccagc aatagttgtg ccaccggggc
    23101 tacaaatagc gtcaatgaaa tcgtgcggac tttgagaact ggtcttgaga ttgctggcac
    23161 tagccaagac tgtttgagta acaatctcca gcgcctttgc tttaggcatg ccattcttga
    23221 cgccagcctt agccaaagcc tcaataaaga gataaatata ggcaggactt gaccctgcta
    23281 aagcggtaaa ggtgtcaaaa tccttttcac taatatcaaa tgtgctacca aagctatctg
    23341 ttaagtctcg aacacgtgct tgtaattcct gggacaccaa agcatttccc gttaaagcgg
    23401 tactgctttg gagaatttgt gcattcatgt ttggcatgat acgtagcagc ggaaggtctt
    23461 gtcctacgaa tgttgctagt cgttgaaggg aaatgcctgc tgccatagat ataataggct
    23521 gtttgaagtg aagcggtttg agtaccgttt caaatagttg aggcttgatg cctaaaataa
    23581 caagatcaac ctgatcaata aggtcttggt gggacatagc ataaggcagt gctaactgct
    23641 ccgcaatttc cttggaccgt tctaaagatg atcctgaaat gataagttca tggggtgttt
    23701 gtttaaggcc tttgatgata gcgctagcca ttttgccaac accaataatg ccaattttca
    23761 ttctgttgct ccttgtggga tattatggtt aatcaggcta acgctagttt agtaacgttt
    23821 aatcaagtca acggttgagc gatccagttt tttgataatg gcttgtaaga aggcttgggc
    23881 ttctacgaaa tcatccatag cgtagagggt ttgatgagag tgaatgtagc gtgcacagac
    23941 tccgatggtt gttgatggga caccaccatt ttgaaggtgt gcagcacctg catctgtgcc
    24001 tcccttgcca caatagtatt ggaaattgac accagcttcc tcagcagtag tcagtaagaa
    24061 gtcgcgcata tctttgagca tgacatggcc tgggtcgtag aaacgcaaca aggtgccatc
    24121 tccgattgtt ccaggattgc cataaatatc accagcaggc gaacaatcta ctgcgaaaaa
    24181 gagttcaggg tcgaacttgg tggttgagac gtgggctccg cgcagaccaa cttcttcttg
    24241 aacgttagca cctgcaatta gggtgttgtt aaggtcttgt ccttttaacg cttcaagcat
    24301 ttctgttatc atgagaacgc catagcgatt gtcccaagct tttgaaataa tatttttttg
    24361 attggctgtt aggatcgttt cagattgagg gacaataata tcacccggtg taataccaaa
    24421 tctttcagct tctgccttat ccgtaaagcc accatcaaac acaatatctt cgatatgtgg
    24481 tagactagca gagccatttg ccccacataa aaaatgggga ggtaccgatc ctgaaataag
    24541 gggaataact tggccagtgc gtgtgtaaag ggtaaaccgt tgtgaactga caacaagtgg
    24601 gttccaacca ccgataccaa ccacgcgtag cgttccgtca actttgatat cactgaccat
    24661 aaaaccgact tcgtccatgt gcgcagctac taaaatacgg ggggcttttt cagctttact
    24721 atctctgata ccaaaaatgc caccaagccc gtctgtttca acacggtcaa ccagcggggt
    24781 tattttggtg cgtaggtagt cacgaacgct atgttcatag cccgcaatgc catccagttc
    24841 ggtaacttct ttgatttttg agaataagtc tgtcattttt catctccatt taaaaggttt
    24901 cagaccagtt caacgcggtc atctccttat attctaccac tttttaagta agaatgggtt
    24961 tcacagaaaa gaaaaatccc agagactaga gatctctgga agaagtgttt gtcttttggc
    25021 gataacctat ttttttaggc agcaaggaaa tcattaaaat gataaagcac aagctggtta
    25081 ataagaatag tagggcgctt aggatgcgaa aagactcttc actagcgaaa agtaaggata
    25141 atggagtcat aaggagaacc ttccatttta ggttaatcag tgatttttat agcgtggtta
    25201 aattaataat aaaccacacc taataaacgt acctttagtt tagttgtttt tactattttt
    25261 gtcaatacat aacagtagaa atctttagtt ttcttatttc agatcgtcca atttgatctt
    25321 tttatgataa aatgagggat atgagtaaaa agaaaatagg tatgatttca ggtatctttg
    25381 gatttagttt agctattggc ctaggaatag ttatcaaaga ttattgccaa gacaggcagc
    25441 gtcgacaaat gacaagggat ttacgcacct ttttttcacc tttaggacaa atcgaagttt
    25501 tatatatcaa tccttgtcag gtcaaacaag attatatttc aggtggggtt gttatgtcaa
    25561 acggcaaaca gtaccaattc acctatcaca gtcgacaaat tagttttgag gaggacaagg
    25621 gatgatcaga ccgacttctt atgagtcatt agcggctctt attgaaaaag aagataagct
    25681 ggtgttattt tttacggcag actggtgtcc agactgtcaa tttatttatc ctattatgcc
    25741 agaaattgaa gcagaactta cagatatgac ttttgtttgt gttaatcgtg atcagtttat
    25801 agaggtagca caaaagtgga atatttttgg tattcctagt tttgtcgtga ttgaaaaagg
    25861 tcaggaagta gggcgtctgg ttaacaaaat gagaaagaca aaaactgaga ttatgcattt
    25921 tttagctgct tatcaataag aaaagaggaa gaataaatga tttttgcata caataaagaa
    25981 caagttggcg atgtcttgat ggttatctta caagacacca aagatatcaa acgtcaagta
    26041 gaacgaaaag gcaaagtagc ccgtgttttt gcagaagaaa gcggcaaaac ccttgcttgg
    26101 aatatctttg aagcgtcaag cttgattact attgaaggca atggacagat ttttttgaca
    26161 gacgaggacc ttgcaagatt aaatgcagag cttgctaagg aaggattttc agaaaggctt
    26221 gaaccgattg tgggacctgt ttttgtggtt ggtcaaattg ttgagatggt ggctcatcca
    26281 gatagcgacc atcttaatat ctgccaagtg gctattggtg aagatcaaac ggttcaaatc
    26341 gtagcgggcg caccaaatgc tgcgcttggt ttaaaaacga ttgttgcctt accaggtgct
    26401 ataatgccaa atggtagtct gattttccca ggaaaattgc gtggtgaaga aagttatggt
    26461 atgatgtgct ctcctcgtga gttagccttg ccaaatgcac cgcaaaaacg tggcattatt
    26521 gaacttgatg agtcagctgt ggtaggagaa gcttttgacc cagccaaaca ttggaaaggt
    26581 tagaaaaacc agctgaaata agactgtatt taactaaatg accagaaaaa aaggattagg
    26641 agcccttaat ccttttttct tatgttttca aaaacgttta aaatgaaact tattttacca
    26701 caatttttac gaataataag ataaggaggt cagtatgtat aataaagtga tagcaatcgg
    26761 tcgtttggta gctaaaccag aattggtaaa aacagctacg gataagcatg tagcacgtct
    26821 ctctttagct gttaatcgaa gatttaaaaa tgcttctgga gagcgagaag cggattttat
    26881 ttcagttgtt gtttggggaa agttagctga aaccttggtt tcttatgcta gcaaaggtag
    26941 tttgatgtct attgatggcg aacttaggac ccgcaagtat gataaagatg ggcaagtgca
    27001 ttatgtgaca gaagttctct gccaatcatt tcaactgctt gaaagtcgtg ctcagcgtgc
    27061 tatgagagaa aataatgtta ctaatgatct agttgattta gtcttagaag aagatactct
    27121 tcccttttga taggggataa tgcttctcat cacggttcag ctgattactg aaatatatga
    27181 tgaggtgata cccgagcaac aaaagtgtga ccagatactt ctgataaaaa taaaaaaaca
    27241 ccttacgagt atgaacaaag tttcaagtgc tagatgttgg aactttgttc atcataggaa
    27301 tagtagggtg ttttttagtg tattacttct ttttgttgct agtgttaagg tttacttgct
    27361 tacaagcggt tatcaggcca ctagaactct tataataaat ggagctcttt gagtttggtg
    27421 tcaatcattt ttaagacagt cgccaaatct tgtgggtttt gaacgaaatc aagggaattg
    27481 ccatcaattt tcatttttgg agagaccttg tagtcttcgt accaggttgg gtattcaccg
    27541 tggacttgat ggtaatattg ctcaagacta ggattgccgt cgacctgctc aaaacttcgg
    27601 ccacgttttt caatgcgctc aagcattttg tcaaaagaca catcaatgta gatgagaaga
    27661 tcagggcgtt ttttaggcat gccttctagt tcttctaaca tgttggcgag aagttcctga
    27721 tagatgtcaa gttctgtctt agtgacattg ccatttttgt agttaagttt taagaagagt
    27781 tcgtcttcaa aaatagagcg gtcaagaatg ttgttatcgg cttgataagc ttctttgatg
    27841 gacttaaacc gtttattcaa aaaataaatt tgaagtaaaa aggcgtactt tttagggtct
    27901 tggtagtaga ggtctagcac ggggttatta tcgacagctt cgtaaaaaac gtcagttcct
    27961 aagtgctctc caagtgcagc agcaagcgag ctcttgccag ccccaattgt tccagctagt
    28021 acaatcaaca tgcgtctcct tctaatgtca ttagcgtact gtttcgaaga tggcttcaac
    28081 ctcagctaga gtctcagcgc gtgaaacagc accacgaact ttggcagcac ctgctgttcc
    28141 gcgaagatag tgtggtgcta agccccgaaa ttcccgaaca gcaatggttt cacctttgag
    28201 gttaatcagg cgtttaaggt ggtctttggc gatgtctaat tttttggcaa agggaagatc
    28261 tggcaattct tgaccagttt caaagaaatg attgatttgg gtaaaaagat aaggattgtt
    28321 catggctgcg cggccaatca tcacggcatc tacaccgatt tcttcaatca taaatttggc
    28381 gtcttgcacc gaacgcacgt ccccatttcc aataaaggga atcttagtga tagccttaga
    28441 aactcgggct aatgtctcat ggtcgcaggt tcctgtatac atttgttcac gggtacgacc
    28501 gtgcatggca agagcagata cacctgccga ctcagcggca agggcattct caatggcaag
    28561 tgaactatcc gcccaacctg tacgcatttt gacagtcagt ggaatatcta aaacagacgt
    28621 gacttccttg acaatgtggt aaatcttatc agggtcacgg agccacttgg caccagcctc
    28681 gtttttgaca actttattaa cagggcagcc catattaata tcaacaatat cggccttggt
    28741 attggtttga atgaaatcag ctgcacgttt caacccttct gcatcaccac caaataattg
    28801 aatggacata gggtgctcat tctcgtcaat atggagcata tggagggtct tttcattgtt
    28861 gtagagcagc cctttttcgg aaatcatttc cataaccacc aaaccagcac caaattcttt
    28921 ggcgatggta cgaaaggcag aattggtcac accagccatg ggagcaagga cagtgcggtg
    28981 agggatttcc acatcaccaa tcctaaagga agaattaagc tttatcattg atgatggcct
    29041 ccaaatcact ttcattaaat tggtacttgg taccacaaaa ttggcaaaca atctcagcac
    29101 ccttatcttc gtcaatcatg gcctgtaaat ctgcttttgg caaagttatt agggctgctt
    29161 caaaacgttc tctagaacag tcacactgaa aactcagagg ttcttcaaaa agacgcttgt
    29221 aaggttcatc tccatagatg gcctccaaaa gggcatccac atgatttttg gaagctagta
    29281 ggtgagaaat ggcaggcatt tcttgtaggc gtttttcata gcgagcaatc tcttcttcag
    29341 aagcgcctgg tagcacctgc accataaagc caccagcaac cttaacctta tcattttcat
    29401 ctaaaagcac attaagtccg attgcagatg gtgtttgctc tgattcggtt aagtagtagg
    29461 caaaatcctc accaatttcc ccagtaataa gaggcgttgt tgaggtgtaa ggggtacctg
    29521 tgccataatc aataatcgtc acaaaatgac cattccccat aaaaggccca acaaggactt
    29581 cacctgttgc ggtcttttta atatcgacac cagtattttg aatgtaacct ttcacatgtc
    29641 ctttggtatc tgccacagag ataatgtgtc caaaagaaga atcaccaatc actttgacgg
    29701 tgattttact atcgcctttt tgattagccg ccaaaatctg gttggcgatc aaggtacggc
    29761 caagcgcaac agtagacgat gacagcgtgt tgtgtttttc ttgagctaat gcaaccgtct
    29821 cagtgctatc aaggacataa gccctaaaag cccctgattg tgctattgat ttaattattt
    29881 tatccataac ttagattata gcataaagtg taaaacttgt attgacagga ttgcttgaaa
    29941 aatcaataca gatagacaat aaaaaatccc agagaatgac tcgggattaa gttaaggtgt
    30001 ggtctaaagt cgcgcaatgt ggtgacatgg cgcttatgtt aattgcttgg ttaaatcagc
    30061 ttggaatttt tcctctttaa cttgatacat caattcttgg atagacagaa tcgattcatc
    30121 aaaagatatt tcagcaacag caattccttt tgtaagttca tggtgaacaa aaggaatcag
    30181 ttgactgtga gtgatgacca aatctggctt taaatcagga atttgataaa cattatcttg
    30241 caatagataa tagggatgaa aatcaatgct tttatccgag aaataccttg gaaaagaatc
    30301 cgttaggaga tgagcattga taaaattact ggctacgaaa acaacaacta aaggaggttg
    30361 gatatttctt agactttgct cgacatagtg gcaaaaaaga tgaaaatgct tatggttcaa
    30421 gtcacgctta ccaggaagtt tggccatcca ttcttcgaca attaacttta aggacgtata
    30481 gagtttttgg tttcctttat agtacggaga aacgaataag ttggtctcag gaataaaatg
    30541 ttgcagatta aacaagaatg attttgaaaa aaacataaga gcttttacta aactagcctt
    30601 ttgctctttt aggctaggta aaagagtgat gataggattt aaaagcaggc gaaaagtatc
    30661 attttcttca aaaagttgac aacattgtct gatatgctca ggtgtccatt gtaagctcgc
    30721 aaaagaatta ttagcggtga tataaattaa atagaggtag tccaaatctc ctgctgaaaa
    30781 gattagttgg cagtaagttt cgataatatc atggctactt tttttcaaag aatcgtagac
    30841 aaaaagtttt tttaattgtt gaaaaattct ggtttgggga atagttaccg aaaattgatg
    30901 ccgcttccac gataaagcca ataaaatgtc atagaaagaa aacgattccg ataaccaagg
    30961 agaggtttta aggtgggtgg aactatggga taaaaagcta tgaatagtgt ttttgtcttg
    31021 ctgcgtcaag tcataaactt taatgccaaa cttactatat agcagagcga taaggtaacg
    31081 gatgcgatat tcctcaccga caatcttgtt cttagagagt tttaattcaa agtttcttaa
    31141 taaaggaatc aatgcttcgc gcatccgata agctgaggag tttgataaaa aatgacttct
    31201 tgcaaaatcc gtaaggggac gagagtggga accatttttt attaaaaacg ctagtaattg
    31261 taagacatta gatgatgcat agagttggta aagataagtt tctttaaaag gatgtgtaaa
    31321 ttggcaagat atcatccttt tttggatggt catagacaga ctaccaggga aaaaggcatt
    31381 cagttcctca cagtaatggt ttagttgtaa aaaggttaag ccagtttttt ctgctacctc
    31441 agttattggc aaataagatg tcttaaaaaa caagataatt aactgacatt ttgattcgat
    31501 tgatgattcc aagtattttt ctatcaagga aagggacctc tcttcctaaa cttagaaagc
    31561 caaataagtc tttgataagt gtattctcct atttcaattc tatctaagct aaaaatagaa
    31621 atcaaatcta atggtttttg gtgaaaagtc gaaacctttt gaaatagctt taaagcaata
    31681 ttttctcaaa aaatcatttt caaaaacatt aatttggtga aaaatataat caaaagattg
    31741 tctttcttga caataacgtg gtaagctcat atatgttttt gagaggagag aaaatgaata
    31801 acaaaatatt tttgaataaa gaagccggtt ttttggcaca cacaaaaaga aaaaggcgat
    31861 ttgctgtcac tttagtggga gtctttttta tgcttttggc atgcgcgggt gctatcggtt
    31921 ttggtcaagt agcctatgct gcggatgaga ggactgtgcc gaattttaaa agcccagatc
    31981 cagattatcc ctggtatggc tatgatgctt atactggagc gtttttaaga tatcatgatc
    32041 ttagagtcaa tttaaacgga agtcggagct accaagttta ttgttttaat attaaaaaaa
    32101 actatcctcg accttttacg agtagtgata aaaaatggta taaaagatta gagggaactg
    32161 ctgaaacttt taaagttcat gctatggctc ccagagtagg gggagaggaa ctaactaaaa
    32221 aattacggag cgttatgtat aacggctacc ctaatgacgg caataatatt atgaaaggtt
    32281 tggagccttc aaatgctata gaagtaacac aatacgcagt ttggtactat tcagataagt
    32341 cacagtatga aattgagaca ttatggaagt ctgaagcgaa agaaggtaag attagtgagt
    32401 cacaagttac tttaatgcgt gaagccctga ggaaactaat ttcctctgat gaagatttgg
    32461 ttaaacaagt tccatcgaac tttaaactta gtacttttga gtcttctgat aagtcctacc
    32521 aaaatctttt aagtgctgag tttgtacctg atgatccccc taaacctggt gatacgtcag
    32581 aacataatcc taaaactccc gagttggatg gtagtcctat tcccgaagac ccaaaacatc
    32641 cagatgataa tttagaacct acattgccgc cagtgatgct agatggtgaa gaagttccag
    32701 aagttccaag cgagagctta gaacctgcgc ttcccccatt gatgccagag ttagatggtc
    32761 aagaagtccc tgaaaaacct agtgttgact tacctattga agttcctcgt tatgagttta
    32821 acaataaaga ccagtcacct ctagcgggtg agtctggtga gacggagtat attaccgaag
    32881 tctatggaaa tcaacagaac cctgttgata ttgataaaaa acttccgaat gaaacaggtt
    32941 tttcaggaaa tatggttgag acagaagata cgaaagagcc agaagtgttg atgggaggtc
    33001 aaagtgagtc tgttgaattt actaaagaca ctcaaacagg catgagcggt ttcagtgaaa
    33061 cagtgaccat tgttgaagat acgcgtccga agttagtgtt ccattttgac aataatgagc
    33121 ccaaagtgga agagaatcgg gaaaagccta caaaaaatat aacacctatc cttcctgcaa
    33181 caggagatat tggaaatgtt ttggcctttc ttggaatcct tattttgtca gtactttcta
    33241 tttttagtct tttaaaaaac aaacaaaaca ataaagtctg acgtaaaagt gttccataag
    33301 aaataatgcg caaatatgct gaatagtgga taactgctac agtcaagaca agtgttaatt
    33361 caaaaggtac tacttataca tctgataata ataaggtgac agataattca gagcaagtag
    33421 gatggctaaa aaatgatgta ttctatgcat aatagactta caagaaatca agttattgtt
    33481 aaacgtcgta aagcttaacg ctttcaaaag tcgaaatcaa tcgagactgt ctttaggcag
    33541 tctcgatttt tattgataag gaactgcaat gacagaaaga ctaaaaaatc tagggatact
    33601 cttattattt ttattgggaa cagccatttt tctttaccct acgctaagta gtcagtggaa
    33661 tgcctaccgt gatcgtcaat tgttatcaac ttatcacaaa caagtgactc aaaagaagcc
    33721 ctcagaaatg gaggaggtgt ggcaaaaggc taaggcgtat aacgctaggc ttgggattca
    33781 gcccgttcca gatgcttttt catttaggga tggcattcat gataaaaact acgaaagcct
    33841 acttcaaatt gaaaacaatg atattatggg atatgttgaa gtgccctcta ttaaagtgac
    33901 gttacccata taccactata cgacagacga ggtgctaact aagggagcag gtcacttagt
    33961 tggaagtgcc ttaccagttg gtggcgacgg gactcacacg gttatttctg ctcatagagg
    34021 ccttccatcg gcagaaatgt ttactaattt gaatttagtg aaaaggggag atacttttta
    34081 ctttcgtgtg ttaaataaag tattggctta taaagttgat cagatactaa ctgttgaacc
    34141 agatcaagtc acatctcttt ctggggtaat gggaaaagat tatgctactc tggttacctg
    34201 cacaccatat ggtgttaata ccaagcgtct attggtcaga ggtcatagaa ttgcatatca
    34261 ttacaaaaag tatcaacagg ctaaaaaagc aatgaaactc gtggataaat caagaatgtg
    34321 gacagaagta gtatgtgctg ctttcggggt ggttatagct attattttag tatttatgta
    34381 ttcaaagatg actgataaaa aagtgattaa aaactaactt gccctgaacc ttctttatcg
    34441 tattgcaact gtcataaaag taaaataatc tggtagttac tatccccttt gatgaagttt
    34501 aattaaatct catcaagaga aaaatattag gcgattacaa atgattttcc caaaaattat
    34561 tttttggaac gcataatatg gaaaaaaaga tgataagaac aactgtttta aacatcaaat
    34621 aaatgatata gtagctatga aatagcattg tgactgtccg gtaaagggat gggactgaag
    34681 attttattca gaaggagagg gaatgaataa caaaaaattg caaaagaagc aagatgctcc
    34741 tcgggtatca aacagaaagc caaaacaatt aactgtcact ttagtgggag tatttttaat
    34801 gctcttagta ttgataggat ttgaaggaaa agttcgagca gctcacgaat tggttgaggt
    34861 accagtacct atttttcaca atccagatcc acagtcagac tatcagtggt atggctatga
    34921 agcctataca ggggggtatc cgaagtatga tttattcaag acatactatc atgatctgag
    34981 agtgaatttg catgggagta aaagttatca agtatattgc tttaacgttc acaaacacta
    35041 tcctcgttcc tcccagagtt ttgatcggaa gtggtataaa aaattagatg gaactgctga
    35101 gaattttgat tctcttgcta tggaaccaag agttcgtaaa gaggagttaa ccaaaaaact
    35161 ccgagctgtt atgtataatg cctatcctaa tgatgctaat ggcattatga aagatttaga
    35221 gcctttaaat gctattaaag tcactcaaga ggctgtatgg tactattctg attcagctca
    35281 aattaatccg gatgaaagtt ttaaaacaga agctcaaagt aatggtatta atgaccagca
    35341 gttaggctta atgcgaaaag ctttaaaaga actaattgat ccaaacttag ggtcaaaata
    35401 ttcgaataaa actccatcag gttatcggtt aaatgtattt gaatctcatg ataagacttt
    35461 ccaaaatctt ttgagtgctg agtatgttcc ggatactccc ccaaaaccag gagaagagcc
    35521 tccggctaaa actgaaaaaa catcagtcat tatcagaaaa tatgcggaag gtgactactc
    35581 taaacttcta gagggagcaa ctttgcgttt aacaggggaa gatatcccag attttcaaga
    35641 aaaagtcttc caaagtaatg gaacaggaga aaagattgaa ttatcaaatg ggacttatac
    35701 cttaacagaa acatcatctc cagatggata taaaattgcg gagccgatta agtttagagt
    35761 agtgaataaa aaagtattta tcgtccaaaa agatggttct caagtggaaa atccaaacaa
    35821 agaagtaggt tctccatata ctatagaggc atacaatgat tttgatgaat ttggtttact
    35881 gtcaacacaa aattatgcga aattttatta tggaaaaaac tatgatggca gttcacaaat
    35941 tgtttattgc ttcaatgcca acttgaaatc cccacctgac tcggaagatc atggtgctac
    36001 aataaatcct gactttacga ctggtgatat taggtatagt catattgctg gttcagattt
    36061 gataaaatac gctaatacag ctagggatga agatcctcaa ttatttttaa aacacgtaaa
    36121 aaaagtaatt gaaaatgggt atcataaaaa aggtcaagct attccatata acggtctgac
    36181 tgaggcacag tttcgcgcgg ctactcaact ggcaatttat tattttacag atagtgttga
    36241 cttaactaag gatagattga aagacttcca tggatttgga gatatgaatg atcaaacttt
    36301 gggtgtagct aaaaaaattg tagaatacgc tttgagtgat gaagattcaa aactaacaaa
    36361 tcttgatttc ttcgtaccta ataatagcaa ataccaatct cttattggga cagaatacca
    36421 tccagatgat ttggttgacg tgattcgtat ggaagataaa aagcaagaag ttattccagt
    36481 aactcatagt ttgacggtga aaaaaacagt agtcggtgag ttgggagata agactaaagg
    36541 cttccaattt gaacttgagt tgaaagataa aactggacag cctattgtcg acgctctaaa
    36601 aactaataat caagatttag tagctaaaga tgagaaatat tcatttaatc taaagcatgg
    36661 tgacaccata agaatagaag gattaccgac gggatattct tatactctga aagagactga
    36721 agctaaggat tatatagtaa ccgttgataa caaagttagt caagaagctc aatcagcaag
    36781 tgagaatgtc acagcagaca aagaagtcac ttttgaaaac cgaaaagatc ttgtcccacc
    36841 aactggtttg acaacagatg gggctatcta tctttggttg ttatttcttg ttccatttgg
    36901 gttattggtt tggctatttg gtcgtaaagg gactaaaaaa tgactaatta cctaaatcgc
    36961 ttaaatgaga atccactatt gaaagctttc atacggttag tacttaagat ttctattatt
    37021 ggatttctag gttacattct atttcagtat gtttttggcg tcatgattgt taacacaaat
    37081 cagatgagtc ctgctgtaag tgctggtgat ggagtcttat attatcgttt gactgatcgc
    37141 tatcatatta atgatgtggt ggtgtatgag gttgataaca ctttgaaagt tggtcgaatt
    37201 gccgctcaag ctggcgatga ggttaatttt acgcaagaag gaggactgtt gattaatggc
    37261 catccaccag aaaaagaggt cccttacctg acgtatcctc actcaagtgg tccaaacttt
    37321 ccctataaag ttcctacggg tacgtatttc atattgaatg attatcgtga agaacgtttg
    37381 gacagtcgtt attatggggc gttacccatc aatcaaatca aagggaaaat ctcaactcta
    37441 ttaagagtga gaggaattta aaaaaatttg gagagagaga aaatgaaaaa aaacaaatta
    37501 ttacttgcaa gtacaatttt ggctactgct ttgggaatga ataatttagc atcagctgaa
    37561 gtaaattatg taaaatcagg agttattgat ggtgcaaagt tagaaatcca taaaacaatt
    37621 aagaattatg atgatgataa agttttaatg ccaaatgtga ttttcaagtt taatattaag
    37681 ccagatgatt cagttgttgc tggtaaaaaa gaagaaaaat cgggattaga tataaaacca
    37741 ggtatagttg atgggttgga aactagtaag gaagtatctt atacaaatag cgacaaacca
    37801 aatagtaaag ataaatatac ttactttgat ttttctcaag tgaaatttac taatgttggt
    37861 atctatcgct atattgttga agaagtacag gatacagtat ccggtattca ttatgatagt
    37921 caaaaatggt atatagacgt ttatgttgtt gaaggagata atggattcgt tccgaaatat
    37981 attgtatcaa gtaaagcatt ggaaactaaa gaaccagttt tatttagtaa ttcatttgat
    38041 acaacttctt tagttgttaa aaaagaggtt acaggaaata ctggagataa aacgaaaaac
    38101 tttaaattcc aattattatt aaaagagaat gcttatttct cagcaggtca aaaagtttca
    38161 gttacaataa cttctgagaa agcttcagaa gtcacgactg ctaccatagg tcaaccactt
    38221 atctttgagt taaaacacaa tgaacaactt aaattggata aattgcctgt tggtattacg
    38281 tatcaaattg atgaaactag taaaaatagt gacagctaca caacgactgc tacaattcaa
    38341 gaaggtgaac aatcacaaaa ttcttatgtt ttaaactcag ataaggaaac tgataaaagt
    38401 ccagatatta ttacagtcac aaataagcgt gacactcaag ttccaactgg tgttgtaggc
    38461 acccttgctc catttgcagt tcttagcatt gtggctattg gtggagttat ctatattaca
    38521 aaacgtaaaa aagcttaagt gattagtcaa agaatgatga tgacaattgt acaggttatc
    38581 aataaagcca ttgatactct cattcttatc ttttgtttag tcgtactatt tttagctggt
    38641 tttggtttgt gggattctta tcatctctat caacaagcag acgcttctaa tttcaaaaaa
    38701 tttaaaacag ctcaacaaca gcctaaattt gaagacttgt tagctttgaa tgaggatgtc
    38761 attggttggt taaatatccc agggactcat attgattatc ctctagttca gggaaaaacg
    38821 aatttagagt atattaataa agcagttgat ggcagtgttg ccatgtctgg tagtttattt
    38881 ttagatacac ggaatcataa tgattttacg gacgattact ctctgattta tggccatcat
    38941 atggcaggta atgccatgtt tggcgaaatt ccaaaatttt taaaaaagga ttttttcaac
    39001 aaacataata aagctatcat tgaaacaaaa gagagaaaaa aactaaccgt cactattttt
    39061 gcttgtctca agacagatgc ctttgaccag ttagttttta atcctaatgc tattaccaat
    39121 caagaccaac aaaggcagct tgttgattat atcagtaaaa gatcaaaaca atttaaacct
    39181 gttaaattga agtatcatac aaagttcgtt gctttttcaa cgtgtgaaaa tttttctact
    39241 gacaatcgtg ttatcgttgt cggtactatt caagaataac gaaaggagga gacttttgag
    39301 aaaatattgg aaaatgttat tttctgtcgt aatgatatta accatgctgg cctttaatca
    39361 gactgtttta gcaaaagaca gcactgttca aactagcatt agtgtcgaaa atgtcttaga
    39421 gagagcaggc gatagtaccc cattttcgat tgcattagaa tcaattgatg cgatgaaaac
    39481 aatagaagaa ataacaattg ctggttctgg aaaagcgagc ttttcccctc tgaccttcac
    39541 aacagttggg caatatactt atcgtgttta tcagaagcct tcacaaaata aagattatca
    39601 agcagatact actgtatttg acgttcttgt ctatgtgacc tatgatgaag atgggactct
    39661 agtcgcaaaa gttatttctc gaagggctgg agacgaagaa aaatcagcga ttacttttaa
    39721 gcccaaacgg ttagtaaaac caataccgcc tagacaacct gacatcccta aaaccccatt
    39781 accattagct ggtgaagtaa aaagtttatt gggtatctta agtatcgtat tactggggtt
    39841 actagttctt ctttatgtta aaaaactgaa gagtaggcta taaaacccat ttttaagagt
    39901 cacacatttt tagttgctct atttttataa tgaaacttat tgacatctcc acagtcttgc
    39961 ttgactttgg agatgttttc tatgctgata ggtttttgta ccatataaga taatgattga
    40021 tgaaaagagt gtcttgaatt cttaaatatt atctcggtat ttagcaagat agtcttttga
    40081 agaaataccc gtgtattttt taaagatttt atgaaaatgg gtagtgtcat aaaaatataa
    40141 gcttttagcc acttctccaa caggaattcc tcgttttaag agtagttgag cttctttgat
    40201 ttttgtactt agaatataat gttgtaagga aacatttgag tattttttaa agactgaacg
    40261 taagtgagat tcggaaacat ataggcgctt agcgatatca gataccttta atttggaata
    40321 caggtgacta tcgacataat gaagcacact attgtacatt tgacgtttat cagaaatact
    40381 tttattggtt aatgattcgg aaaaatggat gatagctgca cagcgaattc tcaaaacttt
    40441 gagcaagtca ctcgcttctt catttaaggc catgtagtat ttgacaaggc tataatgctt
    40501 tgctacgtca gtattttcta caaaactgaa ttccagtaac ctagttaaat agataacagt
    40561 gaggttcttt tccgccctta gagcagaaat agaagatgag gtgatacttg ataaggggat
    40621 gcgattgatt tcttgcttga gcaattgtgg attgcctagc tttaccagat ccataatatg
    40681 atttaggtgc tctaaaacag gcggtagttg gctagatgct ttgctaatat gcttaaggcg
    40741 atgaatgata tcaggatcag cagtcatctg ttttgaatgc tgcaacaatt gatgaattgt
    40801 ttgttggcaa gtcgtctcaa attgtgtgtc aaaaaaagcg tcaatagcta tcaaaaggtt
    40861 ccgcacatta ttaattggaa aatgtgggac aagtgccata taggataaga gctcttcttt
    40921 gctacgatga gaagaatgtt ttaaaaaatt attagctaat tgttcctgat agtctttatt
    40981 aagtgaataa gggtagaaag gtccaatggc aataatgtag tgacaaagag gaaaaatcat
    41041 aaaggactct tcaaataaac cctcataaaa aataacatct tgtgcagctt gaggaatagc
    41101 tagatgcttt aaaaattgat agtaacataa taaatagtcg tcattaccat atacttgaat
    41161 aagtgcctta tcttgtgaca tcactgaaat aggtaattga gacaagctgt gtaatgtttg
    41221 cacatgtttt aaatcgaata taaccatttg atagattgcc ccccatcctt agttgtatca
    41281 ttttccgtag acttgtaaaa gctttagtaa atgttaatga tgaaaattcc tatttggtag
    41341 gcacactaaa aggtcttcct aatagtaaac tctctctcca tcatctcctg ccttaattat
    41401 actatgaata gctaagcaga taaagataaa ggacttgtac gttaagcgct tgaaaaagaa
    41461 agagttacag ataatgacat aaaaaacgct aaaaaaccat caaaataaat actctgacca
    41521 taagatgtag acttgacaac tgaaaatggt aaaataacta tttgacagtt ggcctgtagt
    41581 ctttagtttt ggacataggc tgtcgcttat gaatgtggag agagaaaata aatgacacaa
    41641 aaaaatagct ataagttaag cttcctgtta tccttaacag gatttatttt aggtttatta
    41701 ttggttttta taggattgtc cggagtatca gtaggacatg cggaaacaag aaatggagca
    41761 aacaaacaag gatcttttga aatcaagaaa gtcgaccaaa acaataagcc cttatcggga
    41821 gcaacttttt cactgacacc aaaggatggg aagggaaaac ctgttcagac ctttacctca
    41881 agcgaagagg gtattataga tgctccaaat ctccaaccag ggacttatac cttaaaagaa
    41941 gataaagcac cagatggtta tgataaaacc agtcggactt ggacagtgac tgtttatgag
    42001 aacggctata ccaagttggt tgaaaatccc tataatgggg aaatcatcag taaagcaggg
    42061 tcaaaagatg ttagtagttc tttacagttg gaaaaatcaa caatgtctgt attctctaaa
    42121 tacggaggga cagaagtaac tagtggcgca gcggatttct accgcaatca tgccgcctat
    42181 tttaaaatgt cttttgagtt gaaacaaaag gataaatctg aaacaatcaa cccaggcgat
    42241 acctttgtgt tacagctgga caaacgtctc aatcctaaag gtatcagtca agatatccct
    42301 aaaatcattt atgacagtga aaatagtccg cttgcgattg gaaaatacga tgccaagact
    42361 catcagctca cctatacttt tacaaattat atcgctggtt tagataaagt ccagttgtct
    42421 gcagaattga gcttattcct agagaataag gttgttttag aaaatcaaac gatatcagat
    42481 tttaagagta ccataggtga tcaggaaatc aaatatggtg ggacagttaa tgtcctttat
    42541 ggaaatgcat ctgggcaaga caacaattat gttactaacg gattgagcaa tgtgggtgga
    42601 agtattgaaa gctacaatac acaaacaggc gactttactt ggtatgttta tgtcaaccca
    42661 aatcgtacca atattcctta tgcgaccatg aatttatggg gatttggaag gttggttaaa
    42721 tctaataact caacaagtaa gtcagaggat tccgctacaa gtagtgccca attggaaaaa
    42781 gtagaaattt atgaagttaa agaggactat acgctaccca ctagttatgg ggttgatcta
    42841 acaaaattga atttaagaaa agaccttgag gcaaagttac cacaagatag tactcaaaat
    42901 tctaataagc gcttgcgaat tgactttgga gataaacttc aaaataaagc ctttgttgtt
    42961 aaaataacag ggaaaacgga tcaatctggt aagccactag tcgttcaatc caatttggcc
    43021 agttttaata atgaaactgc tgtaacttat ggtaatcctg ttaataacgt ctacttccaa
    43081 aacgaaattg ccttgtctcc ttctaagggt agtggttctg ggacaagtga atttactaag
    43141 ccctctatta cagtagcaaa tctaaaacga gtggctcagc ttcgctttaa gaaaatgtca
    43201 actgacaatg tgccattgcc agaagcggcc tttgagctgc gttcatcaaa tggtaatagt
    43261 caaaaagtag aagcaaaatc aaacacacaa ggagaggttc attttaagga cctgacctcg
    43321 ggcacctacg acttgtatga aaaacaagca cctaaaggct atcagcaggt gacagagaaa
    43381 ttggcgaccg ttactgttga tactaccaaa cctgctgagg aaatggtcac ttggggaagc
    43441 ccacattcgt ctgtaaaagt agaagatagc aaagaagtca cgattgtcaa ccataaagaa
    43501 acccttacgt tttcagggaa gaaaatttgg gagaatgaca gaccagatca acgtcctgca
    43561 aagattcaag tgcaactgtt gcaaaatggt caaaaaatgt ccgataaagt tcaagaagta
    43621 acgaaggata acgattggtc ttatcacttc aaagacttgc ctaagtacga tgacaagaat
    43681 caggagtata agtactcagt tgaagaagtg aaagttccag acggctacaa ggtgtcgtat
    43741 ttaggaaatg atatatttaa caccagagaa acagaatttg tgtttgaaca gaataacttt
    43801 aaccttgaat ttggaaatgc tgaaataaaa ggtcaatctg ggtcaaaaat cattgatgaa
    43861 gacacgctaa cgtctttcaa aggtaagaaa atttggaaaa atgatacggc agaaaatcgt
    43921 ccccaagcca ttcaagtgca gctttatgct gatggagtgg ctgtggaagg tcaaaccaaa
    43981 tttatttctg gctcaggtaa tgagtggtca tttgagttta aaaacttgaa gaagtataat
    44041 ggaacaggta atgacatcat ttactctgtt aaagaagtaa ctgttccaac aggttatgat
    44101 gtgacttact cagctaatga tattattaat accaaacgtg aggttattac acaacaagga
    44161 ccgaaactag agattgaaga aacgcttccg ctagaatcag gtgcttcagg cggtaccact
    44221 actgtcgaag actcacgccc agttgatacc ttgtcaggtt tatcaagtga gcaaggtcag
    44281 tccggtgata tgacaattga agaagatagt gctacccata ttaaattctc aaaacgtgat
    44341 attgacggca aagagttagc tggtgcaact atggagttgc gtgattcatc tggtaaaact
    44401 attagtacat ggatttcaga tggacaagta aaagatttct acctgatgcc aggaaaatat
    44461 acatttgtcg aaaccgcagc accagacggt tatgagatag caactgctat tacctttaca
    44521 gttaatgagc aaggtcaggt tactgtaaat ggcaaagcaa ctaaaggtga cgctcatatt
    44581 gtcatggttg atgcttacaa gccaactaag ggttcaggtc aggttattga tattgaagaa
    44641 aagcttccag acgagcaagg ccattctggc tcaactactg aaatagaaga cagtaaatct
    44701 tcagacctta tcattggcgg tcaaggtgaa gttgttgaca caacagaaga cacacaaagt
    44761 ggtatgacag gccattctgg ctcaactact gaaatagaag acagcaagtc ttcagacgtt
    44821 atcattggcg gtcaggggca ggttgtcgag acaacagagg atacccaaac tggcatgcac
    44881 ggggattctg gttgtaaaac ggaagtcgaa gatactaaac tagtacaatc cttccacttt
    44941 gataacaagg aaccagaaag taactctgag attcctaaaa aagataagcc aaagagtaat
    45001 actagtttac cagcaactgg tgagaagcaa cataatatgt tcttttggat ggttacttct
    45061 tgctcactta ttagtagtgt ttttgtaata tcactaaaat ccaaaaaacg cctatcatca
    45121 tgttaagata agctgttggt gacaatagcg aaaaagggtc cacttattag tgggcctctt
    45181 tttctggaat cgatcgtctc ggttcactag ataagtcatt ttaagtagtt caaaaaggca
    45241 gagccttaaa aggttttctg cctttttaat cttgttgggc acttacgaaa gtatttcggc
    45301 caattcaagt ataatacagt cagagtctga gcaatcatgt tgtctcagac tctgactgta
    45361 attatgcaaa aaatgatgga ctggcagctt catttactca ccgaactccc ctttataact
    45421 tgggaatgat gctgctaatg ggttgttttg tttaatacct gctataaacg gtaatttatc
    45481 ccatttattt ttataatctt cttcaagctc agttttaaac ttccaaacca ttttatgaga
    45541 aaaataagtg tgtgattgac ggccataggt gtctactaaa acgtgagaaa attttccgtc
    45601 gttttttagt ttgtaaaatt tatctagaga aggactccag ccagtataac cagggaattt
    45661 atcaaattct tgattaaaat ttgttttttg gttttcccaa ttataatgcc attgtgtatt
    45721 actgcgtgtt ttagaatcaa ctgtaccgtc ccaataataa tgctcataag ttatctctgt
    45781 aggagctttt acacccttag gaagaaaaac tgagaaatca gggtaaaccc attgttcttt
    45841 agctgaatta aaggttacag tccattcgat actgttattg ttatcgacca atgttttagt
    45901 atagtcgaca tagttatcaa catagtaatt tccctgccag taaaggtgca ctttaccttt
    45961 ctcatcaata ttatcatggg catgtactga tttatacgaa ctaaacagca tcgaaactgc
    46021 tagtagtgaa gtgaagagat atttattaca tcgtttcata tcatgaaaaa cctttctttt
    46081 aatactaaca t
//
LOCUS       DAUNLR010000007        45517 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUNLR010000007 DAUNLR010000000
VERSION     DAUNLR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45517
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.007"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..829
                     /locus_tag="VLL59_000399"
     CDS             <1..829
                     /locus_tag="VLL59_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="HER6508549.1"
                     /translation="AVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVE
                     EKSNEIVAIPQLLRTIDIHKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYD
                     DIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRG
                     IGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDYH
                     QTLDKRAAFNLNLIRKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG"
     gene            985..1836
                     /locus_tag="VLL59_000400"
     CDS             985..1836
                     /locus_tag="VLL59_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HER6508550.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            1829..2671
                     /locus_tag="VLL59_000401"
     CDS             1829..2671
                     /locus_tag="VLL59_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HER6508551.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            2649..3236
                     /locus_tag="VLL59_000402"
     CDS             2649..3236
                     /locus_tag="VLL59_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HER6508552.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            3335..3610
                     /locus_tag="VLL59_000403"
     CDS             3335..3610
                     /locus_tag="VLL59_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HER6508553.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            3954..5816
                     /gene="cadA"
                     /locus_tag="VLL59_000404"
     CDS             3954..5816
                     /gene="cadA"
                     /locus_tag="VLL59_000404"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HER6508554.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAEAASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKAK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(6116..7051)
                     /locus_tag="VLL59_000405"
     CDS             complement(6116..7051)
                     /locus_tag="VLL59_000405"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HER6508555.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            7290..7985
                     /locus_tag="VLL59_000406"
     CDS             7290..7985
                     /locus_tag="VLL59_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HER6508556.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            8093..8614
                     /locus_tag="VLL59_000407"
     CDS             8093..8614
                     /locus_tag="VLL59_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HER6508557.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            8775..9317
                     /locus_tag="VLL59_000408"
     CDS             8775..9317
                     /locus_tag="VLL59_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508558.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            9441..10220
                     /locus_tag="VLL59_000409"
     CDS             9441..10220
                     /locus_tag="VLL59_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HER6508559.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFVTNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            11018..11614
                     /gene="recR"
                     /locus_tag="VLL59_000410"
     CDS             11018..11614
                     /gene="recR"
                     /locus_tag="VLL59_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HER6508560.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            11715..12761
                     /locus_tag="VLL59_000411"
     CDS             11715..12761
                     /locus_tag="VLL59_000411"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HER6508561.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVIAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            12960..14351
                     /locus_tag="VLL59_000412"
     CDS             12960..14351
                     /locus_tag="VLL59_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HER6508562.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLYHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMDSNGILIAP
                     GDSIIDPYLPENQMVIRFGGHQELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVADEDIIEALESVQLTANRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAKQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            14431..15126
                     /locus_tag="VLL59_000413"
     CDS             14431..15126
                     /locus_tag="VLL59_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HER6508563.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLEEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLALAFSKEK"
     gene            15374..16918
                     /locus_tag="VLL59_000414"
     CDS             15374..16918
                     /locus_tag="VLL59_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HER6508564.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDVLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            17225..18844
                     /locus_tag="VLL59_000415"
     CDS             17225..18844
                     /locus_tag="VLL59_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6508565.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALAIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDSDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            18971..20971
                     /locus_tag="VLL59_000416"
     CDS             18971..20971
                     /locus_tag="VLL59_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HER6508566.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IVPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNMLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLMMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(20995..21273)
                     /locus_tag="VLL59_000417"
     CDS             complement(20995..21273)
                     /locus_tag="VLL59_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HER6508567.1"
                     /translation="MTTKKAYMYVLECVDKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(21263..22117)
                     /locus_tag="VLL59_000418"
     CDS             complement(21263..22117)
                     /locus_tag="VLL59_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HER6508568.1"
                     /translation="MKVDFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
                     KGKPNHDH"
     gene            22157..22897
                     /locus_tag="VLL59_000419"
     CDS             22157..22897
                     /locus_tag="VLL59_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HER6508569.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKMAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            23097..23759
                     /locus_tag="VLL59_000420"
     CDS             23097..23759
                     /locus_tag="VLL59_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HER6508570.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            23740..25983
                     /locus_tag="VLL59_000421"
     CDS             23740..25983
                     /locus_tag="VLL59_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HER6508571.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLIQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
                     FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTDLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGWTS
                     WHLETVR"
     gene            26054..27094
                     /locus_tag="VLL59_000422"
     CDS             26054..27094
                     /locus_tag="VLL59_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HER6508572.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKVDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            27191..27796
                     /locus_tag="VLL59_000423"
     CDS             27191..27796
                     /locus_tag="VLL59_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HER6508573.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIVNWKKVSELYQAAK"
     gene            27963..28190
                     /locus_tag="VLL59_000424"
     CDS             27963..28190
                     /locus_tag="VLL59_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508574.1"
                     /translation="MLREKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGERQQTA
                     DLKMKKRLEKLFKNRYLKNLKRLSKLLWMQI"
     gene            28175..28423
                     /locus_tag="VLL59_000425"
     CDS             28175..28423
                     /locus_tag="VLL59_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508575.1"
                     /translation="MDADLAQMDVLGLYYDDNHLSLVNTVKAYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            28420..28997
                     /locus_tag="VLL59_000426"
                     /pseudo
     CDS             28420..28997
                     /locus_tag="VLL59_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S11"
     gene            complement(29111..30331)
                     /locus_tag="VLL59_000427"
     CDS             complement(29111..30331)
                     /locus_tag="VLL59_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HER6508576.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(30338..31366)
                     /gene="queA"
                     /locus_tag="VLL59_000428"
     CDS             complement(30338..31366)
                     /gene="queA"
                     /locus_tag="VLL59_000428"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HER6508577.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            31568..32317
                     /gene="nagB"
                     /locus_tag="VLL59_000429"
     CDS             31568..32317
                     /gene="nagB"
                     /locus_tag="VLL59_000429"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HER6508578.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDI
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIKANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLDSPNQSLNLVRTKMRR"
     gene            32391..33107
                     /locus_tag="VLL59_000430"
     CDS             32391..33107
                     /locus_tag="VLL59_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HER6508579.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPIHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            33402..34364
                     /locus_tag="VLL59_000431"
     CDS             33402..34364
                     /locus_tag="VLL59_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HER6508580.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKACQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            34377..36182
                     /gene="pepF"
                     /locus_tag="VLL59_000432"
     CDS             34377..36182
                     /gene="pepF"
                     /locus_tag="VLL59_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HER6508581.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFA
                     GHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMTKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            36558..37754
                     /locus_tag="VLL59_000433"
     CDS             36558..37754
                     /locus_tag="VLL59_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HER6508582.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            37820..38527
                     /locus_tag="VLL59_000434"
     CDS             37820..38527
                     /locus_tag="VLL59_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HER6508583.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTRFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEIFR
                     LLRVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            38590..39645
                     /gene="prsA"
                     /locus_tag="VLL59_000435"
     CDS             38590..39645
                     /gene="prsA"
                     /locus_tag="VLL59_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HER6508584.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            40032..42650
                     /gene="alaS"
                     /locus_tag="VLL59_000436"
     CDS             40032..42650
                     /gene="alaS"
                     /locus_tag="VLL59_000436"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HER6508585.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPGWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYNPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARSAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            43011..43226
                     /locus_tag="VLL59_000437"
     CDS             43011..43226
                     /locus_tag="VLL59_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6508586.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            43223..43984
                     /locus_tag="VLL59_000438"
     CDS             43223..43984
                     /locus_tag="VLL59_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HER6508587.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDIFLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTDQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            44003..44698
                     /locus_tag="VLL59_000439"
     CDS             44003..44698
                     /locus_tag="VLL59_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HER6508588.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(44792..45163)
                     /locus_tag="VLL59_000440"
     CDS             complement(44792..45163)
                     /locus_tag="VLL59_000440"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HER6508589.1"
                     /translation="MQDKLVTEAFNQAYNREKPKEGGIVHTDQGSQYTGAQFQDLLRR
                     KKCKSRMSRKGNPYDNALMESFYKTLKRELVNDAHFATIEQAKLEIFKYSETYYNPKR
                     LHSALGYLSPVEFEKNSYSLA"
     gene            complement(45326..>45517)
                     /locus_tag="VLL59_000441"
     CDS             complement(45326..>45517)
                     /locus_tag="VLL59_000441"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HER6508590.1"
                     /translation="KEMIKAIFYEHKERYGSVRITQELCRRGIHVNYKRVGRLLHQLG
                     LYAKGSRYQYKYYNRRRSS"
BASE COUNT        13995 a         7886 c         9388 g        14248 t
ORIGIN      
        1 tgccgttcat caactgattt cagtggacgg taaaacgatt cgaggcaatc gaggtaaaaa
       61 tcagaagcct gttcatattg taacggctta tgatgggggt catcatctta gtttgggaca
      121 ggtagcggtt gaggagaaaa gtaatgaaat tgttgccatt cctcagttat tgcggacaat
      181 tgatatccat aaaagcattg taacgataga cgcaatgggc acgcagacgg ctatcgttga
      241 tacgattatt aaaggtaaag cagactattg cttagccgtc aaaggaaatc aagaaacact
      301 ttatgatgat attgctcttt attttagtga tgtcaactta ttggaagaac tccaagaaaa
      361 tgcgcagtat tatcagactg ttgaaaaatc taggggacag attgaagtta gagaatactg
      421 ggtgtcttcc gatatcaaat ggttgtgtca aaaccatccc aaatggcata agttacgtgg
      481 tattgggatg actcgtaaca ctattgataa ggatggtcag ctgagtcaag agaatcgtta
      541 ttttatcttt agctttaagc cggatgtcct cacatttgcc aattgtgtac gaggtcattg
      601 gcagatagag agtatgcact ggttattgga cgttgtttat catgaagatt atcatcagac
      661 attggataaa agagccgcat ttaacctaaa tcttatccga aaaatgtgct tatattttct
      721 caaagtgatg gtatttccta aaaaagacct cagttatcgt cgtaaacaac ggtatatttc
      781 tgtccatttg gaagattatt tagtccaatt atttggagaa agaggctaag cagatgattg
      841 atttaaaaag gaatcttttc aaaattgatg tccgggcaca aaaggatgaa gagaaagttt
      901 tcatgcgtac ggcgtgatag cactaccagt tttgctttat ttagtaagga gtgttagaat
      961 aaagaggtga gaaactagtt tagaatggaa aaatacatgg gaactataaa aattgttaca
     1021 gattcatcaa taactattga accagaatta attaaagctt tagatattac tgtagtgcct
     1081 ttatctgtca tgattgatag caaattatat tctgataatg atttaaaaga agaaggtcat
     1141 tttttgagcc ttatgaaggc tagcaaatcc cttcccaaaa ccagtcagcc accggttggt
     1201 ctctttgctg aaacttacga aaatttggtc aaaaaaggag taactgacat tgttgctatt
     1261 cacctctcac cagctttatc aggtactatt gaagcttccc gtcagggggc tgaaatcgct
     1321 gaggcacctg ttacagtttt agattcagga tttactgatc aagccatgaa atttcaggtc
     1381 gttgaggcag caaagatggc aaaagcgggt gctagtttga atgagatttt ggctgctgtt
     1441 caagctatca aatcaaaaac agagctctac attggtgtat ctaccttaga aaatttagta
     1501 aaaggaggtc gtattggtcg tgtgacgggt gttttgagct cgctacttaa tgtcaaagtt
     1561 gttatggcac ttaaaaatga tgagttaaaa acgcttgtca aaggtcgagg taataaaaca
     1621 tttacgaaat ggttagatag ttacctcgct aaaaatagtc atcgcccgat tgcagagata
     1681 gctatttctt atgctggtga agctagcctg gcattaacct taaaagaaag aatcgcagct
     1741 tattataacc actctatttc ggttttagaa acaggctcta tcatccaaac acatacagga
     1801 gaaggagctt ttgcggttat ggttcgttat gaataatcgt catttattta gtgggatatt
     1861 tttctttgtt attagtttat gtctggcctt tttattgtta aatattatta tccctaagtc
     1921 aaattcacgt ttgaaaaaga gtgattttct gaaaaaagaa caagtagcta tccaatatgt
     1981 tgctatagga gattcattga cagaaggagt aggtgatcta actcatcaag gtggttttgt
     2041 tcctttgtta acgaatgatc tcagtgaata ttttaaggct aatgttaatc atcaaaatta
     2101 cggcgtatct ggtgatacca gtcaacaaat tcttgatagg atgataaaac aaaagcagat
     2161 acagttatct ttaaaaaaag cagatataat gacgttaacc gttggtggta atgatgttat
     2221 ggcagttatt cggaagaatt tagcggattt gcaagtttct agttttagaa agccagctcg
     2281 tcagtatcaa aaacgattaa gacagattat cgagttagcc agaaaagata ataaagatct
     2341 tcctattttt attttaggca tctataatcc gttttatttg aattttccag aactaactga
     2401 tatgcaaaaa gtgattgatg actggaatac caaaactaag gaggttgttg gagaatacga
     2461 tcgtgtgtac tttgtgccaa taaatgacct cttgtataaa gggataaatg gacaagaagg
     2521 aattgtccat tcttcaggag atcaaactac aattgtcaat gatgccttgt ttactgggga
     2581 ccattttcac ccaaataata ctggctatca aatcatgtca aatgcagtaa tggagaaaat
     2641 aaaaaagcat gaaaaaaaaa tcaaacctta attggtggaa gtggagcttc ttatgtctgc
     2701 ttgcttttaa taccgccttt ttgatggtta ttgcaagtcg tctcattcaa gtaagagaac
     2761 ctgagtcaga actgattgct aaaaaaccag ttaaaaatat caaaattggt acatttgtca
     2821 caaccagaga acagcttaac gaaactgtag caagttatct taaagattat cagactaaaa
     2881 aaatgtctta taaattttat gcgacatctt cttctatttt gtttgaagga acttatcaat
     2941 tattagggta tgaagtccct ttatatatct attttcaacc tcatcgtcta gaaaatggag
     3001 ctgtccaact acaggtgatc tctttttcag tgggaactct gccactccca gaaaaagatg
     3061 ttttgcagta tttgaaatca agctacaaat tgccaagctt tgttaaagtg atgccaaatc
     3121 aatcagctat cgttgttaat ttacaagata tccaaaatga tgctaaggtt tatttaaagg
     3181 ccaagaaaat tgatttattt aatgatgaaa tcagttttaa catctataag aaataagctc
     3241 aaataacgtt aaatacttga cctaatcgct ttttttagat atgataatat ctgttaaagc
     3301 attaagctta ctaattattt ggaggatttg ttaaatggct aacaaacaag atttaatcgc
     3361 aaaggttgca gaagcaactg aattgactaa aaaagattca gcagcagcag ttgatgccgt
     3421 gttttctaca atcgaagctt tccttgctga aggtgaaaaa gtacaattga tcggttttgg
     3481 taacttcgaa gtacgcgaac gtgcagctcg taaaggtcgt aacccacaaa ctggtgcaga
     3541 aattgaaatt gcagcttcaa aagttccagc cttcaaagct ggtaaagctc ttaaagacgc
     3601 tgttaaataa ttcgtctaga aaaatcttgt tgctatcgat gtttattgat agcgacaagg
     3661 ttcttttttt atatttgggg cataaagtta gtagttttct cttcagttaa gccaagttct
     3721 aaagcatgca ctctataatg gtcagtcatc cttctattag tatatcattt ccgcaggtag
     3781 ggggagtttt tttcatattt gcaaatagtt gaagttaaga tttttgaaag caaaaggtaa
     3841 gtttaaaaaa gtttatttag aatgtttcta aattacttga cttatttatt tagaattatt
     3901 ataattaata tatcttaaag attgaataac ttttaattgc gagggaacta aaaatgacaa
     3961 tcagacaatg gatggcagac catcttcatt tgatggagac tttagcgtgt ttggtattaa
     4021 taataattgg cctagccttt ttacactcat ttccacaagt ggcttccgct attttcatta
     4081 cagccttctt gattggagga tatgcgtctg caaaaacggg tatattggat ttggtgaaga
     4141 acaaacactt gtcagtggat attttgatga ttttggcagc tatcggtgct ggaattatcg
     4201 gctattggct ggagggtgct ctgcttattt ttatcttttc gttgtccaat acgcttgaag
     4261 aaatggccat ggaaaaaagt aaggatgcta tttcagcctt gatgtccttg acgccagata
     4321 cagctcgtca ataccaagaa gatggccata ttttagaagt tgagaccaga tccttgagtg
     4381 ttggtgaccg tttacaagtt cgtaaaggcg aagctgttcc aattgacggg cagttgctta
     4441 gtccttttgg tcaatttgat gaatctatgg tcactggtga gcctatcact gttgataagg
     4501 cagaaggcca ggatctgatt gggggaacca ttaaccaagg acaaaccata gatatgttgg
     4561 ttactattga aaatgacgat actctctttg ccaagattat taatctggtg gaatctgccc
     4621 aagaaaagaa aagcaaaacc gccaccttta tcgaaagctt agaagatggt tatgtcaaat
     4681 ttgtgctcgt ccttattcct gcctttatcc tctttagtca ctttgtgctt tcttggactt
     4741 ggttggctgc tttttaccga gggatgattc tcttaacagt agcttcacca tgtgccctaa
     4801 ttgccagttc cacacctgct agcttggctg ctatttctcg tgcagccaga aagggattga
     4861 ttatcaaagg aggggatatt gtcgataaca tgggagatat taaggctgtt gtcatggata
     4921 aaacgggaac gctcacccaa ggaaaacctt ctgttgtgaa tgctcattat ttggaagatg
     4981 agttgctcgt gaatagactg gtaaaaggag cagaggctgc tagtacccat cctatttcta
     5041 aagcccttct tgaatacact gaaaagttgg agccactgac ctttgaccac ttagaagaaa
     5101 tttctgggaa aggttttcag ggcttctatc aagggcaaga atggcgaatt ggcaagaaaa
     5161 ccttcatttt ggaaaaggtt caagacctat cagcttttga agaaactatt caagtggaag
     5221 aaaatcaagg gaaaacccta atctttgttt cacgtgacca tcaattgata gcttactatg
     5281 ccctcttgga tgatatcaaa atagaatcaa aacgtgctat taagtctctt catgccatgg
     5341 gaatcaaaac agtcatgtta acaggtgacc aagaacgaac cgccaattat gtggcacaaa
     5401 aacttggtat tgatgaagtg gtagccaact gtatgcctca agataaggtg gctaagttag
     5461 cagaattaaa ggctaaatat ggttttgtgg ctatggtagg agatggtatt aatgatgctc
     5521 ctgcccttgc tcaagcagat gtttcttatg ctattggatc aggaacagat attgcaatgg
     5581 aaagtgcaga cagtgtgatt atggatgact tgactcgtat tccattttcg attcaacttt
     5641 cccgcaaaat gaagaccatt atcaaacaaa atattgtttt tgccttatct gtgattacct
     5701 tattgatttt agccaatgtt tttcaggtag ttaacttgcc gcttggtgtt gttggacacg
     5761 aaggctcaac gattttagtg attttaaatg gcttgcgttt actttctttt aaataattta
     5821 gaaacttgct tgaaaacttg aaagtgttta taataatagt aagacttatg aaagagaaaa
     5881 ccgccgtatg tttactatta tgatcattgg tttagctgta ttttcaataa ttaaaatcat
     5941 tctatttttc tatttttatc agcaatttga gcgcaagcaa aaaagaaaag ttgaatcaaa
     6001 caaccagcaa agacagtccc aagaaagtga cgctgtccct tcaaaaaaat tcccatttta
     6061 aaaagcttgg aaagtgtaca aagtgcacat ttccaagctt ttttgactat taaggttaat
     6121 ctttgtaacg taagttccca cgaaaatcgt ctaagctttg gtagcctttt tctaccataa
     6181 tcgtttttag ttccttagtg acccgttcaa agatagctgg cccttcttga tgaagggctg
     6241 tcccaatttg gaccatgctg gcgccacaaa gaatatgttc aaaggcatcg cgtcctgttt
     6301 taactccccc tgtaccaata atgtggatag aaggttttaa gcgtttgtaa aacgcatgga
     6361 cattggctag agcagtaggt ttgatgtaat ctccacctat accaccaaag ccatttttag
     6421 gcttgatgag gacttgttca tcctcaatga ccagcccatt tccgatagaa ttgacacagt
     6481 taacaaagga aagggggtat ttattgaaaa tcgcagccgc ttgatcaaaa tgcacaatgt
     6541 caaaataagg aggtaatttg ataccaagag gtttagtgta ataggtaaag atgttctcta
     6601 gaagttgatc agtggtttca aaatcataag caatctgtgg ttttcctgga acgttagggc
     6661 aagaaaggtt tagttccact agaccctcat aatctgaagc catgatggct tttaaaatgg
     6721 tttcggtttc agtaggagat agcccgacaa cggagagaaa gtgaggttta tgttgcccgg
     6781 ttttggcaag atcactgaca aagtctaagt agtagcgaaa accattatta gggagtccca
     6841 ttgaattgat agaaccaaga cgagtatctg cgtagcgagg ttctggatta cctggacgaa
     6901 cttcaagcgt ccctgttttg gtgacaaagg aagcggcttg agacttttca acctccataa
     6961 gctcttcttt tgtcatgcag taaacaccag cagcattcat caaacagtta tcaaaagaga
     7021 aatgaccaat ttgtgtagca gtagaaacca ttatttcctc catattttag acaaattttt
     7081 tctattctac cactaggcat gaataatagc aagctatttt tacaaaaatg taaatatatt
     7141 actgttattg acgaacattt gaaattttca tgatagtcac attatgattt tcaataaagt
     7201 cagaatagac tagctttttt gctatatttt ttgtaaaata ggaattgtaa aaaggtagca
     7261 acctttaaat taaaaggaga tattaactca tggtaaaatt ggttttcgct cgccacggtg
     7321 agtcagaatg gaacaaagct aacctcttca ctggttgggc agatgttgat ctttcagaaa
     7381 aagggacaca acaagcaatt gatgcaggta aattgatcaa agaagcaggc attgaatttg
     7441 accttgcttt cacttcagta ttgacacgtg ctatcaaaac aactaacctt gcccttgaaa
     7501 atgcaggtca attgtgggtt ccaactgaaa aatcatggcg cttgaacgag cgtcactatg
     7561 gtgctttgac tggcaaaaac aaagctgaag ctgcagaaca atttggtgat gaacaagttc
     7621 atatctggcg tcgttcatac gacgtgttgc cgccagctat ggctaaagat gatgagtatt
     7681 cagcacacaa agaccgtcgt tatgctgatc ttgacccagc ccttattcca gatgctgaaa
     7741 acttaaaagt aactcttgaa cgcgcaatgc cttactggga agaaaaaatt gctccagctc
     7801 ttcttgacgg taaaaacgtc tttgttggtg cacatggtaa ctcaatccgc gctcttgtga
     7861 aacacattaa aggtctttca gatgacgaaa tcatggatgt ggaaattcca aacttcccac
     7921 cacttgtttt tgaattagat gaaaaactta acattgttaa agaatactac cttggtggtg
     7981 aataacttaa aaaccagact ttggtctggt tttttgggtt ctatatccta agaagaaaga
     8041 aaaccctgct taaaaatatg atatgataga aataaaaaag gatagataga ttatgaaagc
     8101 agaagatcgt cgtcaaaaaa ttattgagtg cttaaatagt gaacaaaaag ctgtatctgc
     8161 tactcgttta ggtaagttat taggagtgag tcgccaagta attgttggag atatagctct
     8221 tcttcgagct cagcagattg atattatttc gactccaaaa ggttatatta tgtcaacagc
     8281 gctttatagt caccaatttt gtgcacgtat tgtgtgccaa cataatgtag aagaaactaa
     8341 aaaagaatta gaaattattt tagctcatca agggattatt acgacggtag aggtagaaca
     8401 tcctatttac ggtatgataa cagccccttt aaatattaag acacactctg atgtaactaa
     8461 tttcatgtcc aaactcagtc aatctaaagc agagttattg tcttcgttga cagaaggact
     8521 acatagtcac ttaatttcgt gtcctagtca agaagccttt ttagctatca agcatgattt
     8581 agaattagca ggtatcttat acaaaggaat ataactacag tatattatgc cattgatggt
     8641 tgttatgaat accatgctaa aatattctat tgattattta tcagcaacaa ggtaccgttt
     8701 aaaaatacca aaagatacag gtgtcttgat agttattggt ttttaaggta tactattttt
     8761 gaaaaggaga taaaatgact aaaaaaccaa cacaattaat agcttatacc tctattttgg
     8821 tcgcatttgc gattttgatt ccgataatca tgcctcttaa gcttattatt gggccagctt
     8881 cctttactct ggcgagccat gttcctttgt ttttggctat ttttatgtcg attccagtag
     8941 caattttggt cgctcttggt accacattag gttttttatt agctggactt cctttaatta
     9001 ttgttttaag agcactctct catttattgt ttgctatttt ggcagcgtgg tggttaagta
     9061 gaaaaccaca actgatgaca tcggcagtaa aatgttttag ttttgcgttt ttcattaatg
     9121 tcattcatgg cttggctgaa tttttagttg tctatatttt aacagcaacc acagcaactt
     9181 ctatgtctta tttttggtct atgctaggct tgattggctt aggttcgctt attcatggca
     9241 tattggattt ctatcttgct ttagttctat ggcgtttttt agcaaaaaac ttaaaacttc
     9301 ccaccataaa tgcctaagac taaaatagag atagttatat gataatgacg agccctttct
     9361 tgttgaaagg gcttgcattt tttaggaaaa ttgatatact aaagtgtgtg tttgtgaata
     9421 cagtaacaaa aggagatatc atgaaaacac cagaacagat tttagaagca actattcata
     9481 ttggggaaca taaggttacc aaaacttttt tggctaaatc tatcttaggc tttattggtg
     9541 gagcgatgat tagccttggt tatttactct acgtgagaat tgccgccagt ggtttagaaa
     9601 cttttggtgc tttttccagt atcgtaggag cttgtgcttt tccgattggt ctaattatta
     9661 ttttaatggc gggtggagaa ttaattacag ggaacatgat ggctgtttct gcagctttgt
     9721 tggccaaaaa aattaagttt agcgagcttg ccaagaattg gcttatcatt accttgttta
     9781 atgtgattgg agctgttttt gtagcttttg tgtttggtca ttttctaggc ttgacatcag
     9841 ctggtatttt taaagaagaa gtgattgagg tggcccatgc taaaatagca gcgagccctt
     9901 tgcaggcact agtatcagga attggttgta actggtttgt tggtttggcc ttgtggctat
     9961 gctatggggc aaatgatgct gctggtaaat tccttggtac ttggtttcct gtcatgacct
    10021 ttgtagccct tggttttcag catagtgtag caaatgcttt tgtcattcct gctgctattt
    10081 ttgaaggagg agcaacatgg ttggattttg tcactaattt tatttttgtc tatagtggta
    10141 atattatcgg tggagccatt tttgttagtt ttttatattt taaagtttac tatcatccgc
    10201 aaaagagtaa aactcaatga gaaaatattt ttttagactg agggcgtcct attctcagtc
    10261 ttctttttat aatttatggt aaaataagaa gcgaagttta aaaaatttag ctaaataatg
    10321 gttagtttat tccctaaaaa atgagtattc ccaaaaaatc cgtaaaaaga atttgctatg
    10381 ggagtagttc ccaaaataat gtagatcatt agttgtcttt caaaaatagc cttgttaggg
    10441 taaaaagtgg acagtgatgc agcaacagat tcatcaggcg tacaaactgt cttatggttt
    10501 gtgcttagag atttcttaat actgcttttg gtaatatact tttagtgaag aaagtgtagc
    10561 atgaaagctt aaagataacc atgagtttgc tttatgcact attgttgaga aaaatagcat
    10621 agtcaattga gtaaacatca tttctgcatg gaatgaaaca attcctataa acttatatca
    10681 taaggatggt ttgcggtttc taaaaaagta acatgaatca aaaaacaaaa gccaaatatc
    10741 tcaaggccaa ggtaacaagt cgagtaaaaa agtttttact tggctaatcc aaacggttct
    10801 gtcacgattc acgctaaaat tggaactgct gagacttgta tcacagacaa ttcagatcag
    10861 accttagtaa cttacaactt aaatgtagta gcttataata caaataacga agataatatt
    10921 gcggttgctg ttatgtatcc acatattacg aatatatcgg caaagatgtg agggcgcttt
    10981 atgtggcgat atatggaaaa caataaagga gaacttagtg ctttatccaa cacccattgc
    11041 aaagttaatt gacagttact ctaaacttcc aggaattggt atcaagacgg cgacgagatt
    11101 agccttttat actattggaa tgtcaaatga agatgtcaat gattttgcta aaaacttatt
    11161 agcagctaaa agagaactga cctattgttc gatttgtgga aaccttaccg atgacgatcc
    11221 ttgtcacatt tgcacagaca cgagtcgtga tcagacgacc attctggtag tagaagatgc
    11281 taaagatgtt tctgccatgg aaaaaatcca agagtatcat ggctattatc atgtgcttca
    11341 cggcttgatt tcgcctatga atggtgtggg gccagatgac atcaacctta aaagtttaat
    11401 tacccgtcta atggatggta aggtgagcga agttatcgta gctaccaatg ccacagcaga
    11461 tggggaagca acgtccatgt atatttcacg tgtcttgaaa ccagccggga ttaaggtaac
    11521 tcgtttggca agaggtctcg cagtaggttc agatattgag tatgctgatg aagtaacatt
    11581 attgagagct attgagaatc gtactgaact ttaatgatca tgttggtgcc tttactcgca
    11641 aagagaggtt ttgaaaaggc tacatctttt tgttataata aaaaaacatt caattcagat
    11701 aagaaaggtt agctatgtcc aaacaaacgt tagttctatt atacggaggc cgctcagcag
    11761 aacgtgaagt ctcagtgctt tcagcagaga gtgtgatgcg agcagtcaac tatgataagt
    11821 tcttagtaaa aacttatttt attactcaga tgggccaatt tatcaaaact cagcaatttt
    11881 cagaaaagcc atcggaatca gaacgcttga tgacaaatga gacgatagag ctaactcaaa
    11941 aaataaaacc aagtgatatc tatgaagaag gtgcagttgt atttcctgta ttacatggac
    12001 ctatgggaga agatggctct atccaaggtt tcttagaagt gcttagaatg ccatatatag
    12061 ggactaatgt catgtcttct agcatagcta tggataaaat tactactaaa cgtgtcttag
    12121 aatcaattgg aattccacaa gttgcctata ctgtttatat tgacggacaa gatttggagg
    12181 cttgtttagt tgaaacttta gcaagactta cttttcctat cttcgtaaaa ccagctaata
    12241 tgggttcttc tgtggggatt tccaaagccc aaacaaaagt agaattaaga aaagcgattc
    12301 agttagccct gacctatgac agtcgtgtct tgattgaaca aggcgtgatt gccagagaaa
    12361 ttgaagttgg tctccttgga aatgataagg ttaaatcaac tctaccagga gaagtaatca
    12421 aggacgttga tttttacgac taccaagcaa aatatgttga caataagatt acgatggcca
    12481 ttccagcaga tgtagaccag agtattgtga cagaaatgcg ttcttatgct gaagtagcct
    12541 ttaaagcctt aggtggttgt gggttgtccc gttgtgactt tttcttgacc caagacggac
    12601 aggtttacct taacgaatta aacaccatgc caggctttac tcaatggtct atgtatccac
    12661 tcttatggga aaatatggga ttggcttatc cagatttgat tgaagagctg gtgacactgg
    12721 cacaagaaat gtttgaccag cgtgagagcc acctgattta aacctatgag atgaataaac
    12781 attgacttgg atggaacggc aaacatcgtc aagatgtgac gttcgtcctt tttttgttgc
    12841 tcttttagga agaatagtag agccattaag ggagtttgac attttagaaa tttttctaat
    12901 gttttgtgct ataatagata ggacatcgta aatactagtg ttcttagaaa gaaaacaaaa
    12961 tgaaattaac cttacacgaa gtggctaaaa tagttgatgc ccaaaataat gtgtctgact
    13021 tagacgacgt tcctctgtat cacattgaat ttgatagccg aaagattaca aaaggagacc
    13081 tctttttacc cttaaaaggt caaagggatg gtcatgagtt tattgattta gcctttcaaa
    13141 atggagctgt cgctactttt tcagaaaaag aattgccggg gaaacctcac cttcttgttg
    13201 aagactgcct aaaagctttt caaaagctag cccattatta tattgataag atgcgcgtgg
    13261 atgttattgc tgtgacaggc tcaaatggta aaacttccac caaagatatg ataggagctg
    13321 tcctatcaac cacttacaaa acttacaaaa cgcaaggaaa ttacaataat gagattggtt
    13381 tgccttacac cgttctccac atgcctgacg atacggaaaa aattgttctt gaaatgggac
    13441 aagatcacat gggagatatt cgtcttctgt ctgaaattgc aaggcctcgt attgcagttt
    13501 taaccttagt cggcgaagcc catttagaat attttgggtc acgtgacaag attgctcaag
    13561 ggaaaatgca aattgttgat ggaatggatt caaatggcat tttaattgcc ccaggtgatt
    13621 cgattatcga tccttatctt ccagaaaacc agatggtcat tcgatttggc ggccaccaag
    13681 aattgaatgt tactgatatt cgagaagaaa aagatagctt aacgtttaca acaaatgtgt
    13741 tagcaacacc tgtgtcccta cctctaccag gaaaatacaa cgcgaccaat gctatggtag
    13801 cagcctatgt tggcaaattg ttggcagtag cagatgagga tattatcgag gcgttagagt
    13861 ctgttcaact cactgctaat cgtacggagt ggaaaaaagc agccaatggt gctgatattt
    13921 tatcagatgt ctacaatgct aacccaacag ccatgcgtct gattttagaa acatttgcta
    13981 acatagcaaa gaaccccgga ggaaaaaaga ttgcagtgct agcagatatg aaagaacttg
    14041 gaaaggattc agtgatactt cattctcagt taattgacag cttaacatca ggtaatattg
    14101 atcagcttgt tttttatggg gatcatatta aagaattagc acggttggca agtcaggttt
    14161 atcctgctaa gcaagtacat tattttttaa aaactgaaca agaagaccag tttgaagcca
    14221 tggcacaata tgttcaaaac attcttaatc cctttgatca aattctttta aaaggcagcc
    14281 actcgatgtc gctagaaaag ttagtagatc gattagtgac tgacaagaat tgtgacagct
    14341 atcagccttg atttttataa aactttcaga gaaaggcttg ttctctcatg aagattaagg
    14401 tataatgaaa aaatatagaa agggacgatt atggattttt ttgcaattga ccccatcgga
    14461 ctgcctcata cctcacttat cttttacttg tcgtcactct tgatagcgct tttgcttgtt
    14521 tttttgactt ttcaagcata taggttaaaa tcttatcgtt attttttctt gtttttacag
    14581 ttatctcagg tgattggctt gtacacatgg tacgtgttaa gggggtttcc tttagaggaa
    14641 gctttgccgt tgtatcattg tcgcatcgct atgttagcta tcttttttct acctgatcgt
    14701 aacaagttta agcaattatt tatggttttg gggataggtg gaacattcct tgcactttta
    14761 tcgccagatc tttatccgtt tagattatgg catgtagcaa atgtctcgtt ttatcttggt
    14821 cattatgctt tgttagtgaa tggtttgatt tacctcttgc gtttttacga tgccagtcag
    14881 ttaagactgc tatcggtagt acgctattta gcaactgtta actttcttct tctgttggtc
    14941 agtttagcca cgaaaggaaa ttatggtttt gtgatggata ttccagtgat tcatacgcgt
    15001 catttgctac ttaattttgt gatcgttaca agtggcttga cttttatggt taaaataacc
    15061 gaatattttt accttaaatt tggtgaagct caacagctgg cacttgcttt ctctaaagaa
    15121 aagtaggtcg ttgaaaaagc acttaaaatc agctataata agaagagtct gggatgattt
    15181 ccaggctcga tttttttaaa aaagacactc attgatagcc caagataagt tataatacca
    15241 gttttgaaga actttagagg ctaatcgtat atggagaaac ccaatgtagc ccaactcttt
    15301 tgataaacaa ataataccta acgaaaataa ctcagagaaa agctctgcca ttttactata
    15361 caaggaaaaa agaatgtcac ttacagaaga aattaaaaaa cgccgtactt ttgccatcat
    15421 ctctcacccg gatgctggta agacgactat tactgagcaa ctattatatt ttggtggtga
    15481 aattagagaa gcagggacag taaaagggaa aaaatcaggt acgtttgcaa agtccgactg
    15541 gatggatatt gaaaagcaac gtggtatctc tgttacttca tctgttatgc aattcgatta
    15601 cgcgggtaag cgtgttaata ttttggatac acctggacat gaggatttct cggaagatac
    15661 ataccgtacc ttaatggctg tggatgcggc tgtcatggtt gtagattcgg ctaaaggtat
    15721 tgaggcgcaa acgaaaaaac tttttgaagt tgttaagcat cgtaatattc cggtttttac
    15781 gtttattaat aaattggacc gtgatggacg tgagccttta gaactcttgg aagaattaga
    15841 agaagtttta gggattgctt cttatccgat gaactggccg attggtatgg gacgcgcctt
    15901 tgagggctta tatgatttac ataataaacg tttagaactc tataagggag acgagcgttt
    15961 tgcaagtatt gaagacggtg atcagctgtt tgccaataat cccttttatg aacaagtcaa
    16021 agaagatatt gaacttcttc aagaagcagg taatgacttt tcagaacaag ctattcttga
    16081 tggtgaccta actccagtct tttttggctc tgcccttacg aactttggag ttcagacttt
    16141 tcttgatact ttcttggagt ttgccccaga acctcatggt cacaagacta cagaaggtaa
    16201 tgttgttgac cccttagcta aagatttttc aggttttgtc tttaaaattc aagctaacat
    16261 ggaccctaaa caccgtgacc gtattgcttt tgtgcgtatt gtttctggtg aatttgagcg
    16321 cggtatggga gttaatttga cacgcactgg caaaggcgct aagctctcca atgttactca
    16381 atttatggca gaatcacggg aaaatgtgac gaatgctgtt gctggggata ttatcggggt
    16441 ttatgataca ggaacttatc aagttgggga taccttaaca gttgggaaaa ataaatttga
    16501 atttgaaccc ttaccaactt ttaccccaga aatcttcatg aaggtttctc cgaaaaatgt
    16561 tatgaagcag aaatccttcc acaaaggtat tgaacaatta gtacaagaag gagcaattca
    16621 gctttataag aattatcaga caggcgaata catgctgggt gctgtgggtc aactgcagtt
    16681 tgaagtcttt aaacatcgta tggaaggtga atacaacgct gaagttgtga tgacaccaat
    16741 gggtaaaaag actgttcgct ggatttcaga agatgttttg gatcaacgca tgtcctcaag
    16801 ccgaaacatt ttagctaagg atcgttttga ccaaccagtt ttcctatttg aaaatgattt
    16861 tgcccttcgc tggtttgcag acaaataccc agatgtcact ttagaagaga aaatgtaatc
    16921 gaaacatgat tttcaacagt ctaacgtttt ggagatcaat ttactgagca actttttaaa
    16981 agaaatgagt ggctagttat ctcttttgca gatttaagat tctatcaaaa aacgatatct
    17041 tcacaactgt aagcatattt atgatttagc ggataatcgt gaaagcgtgt tattgcttat
    17101 attagcctta tttcctatct ttttgattct aattgtgtta cactagttag gttgttaatc
    17161 aaacgacgaa aattaaaagg tttataaggc agcttcgcac tgccttttta gaaaagagaa
    17221 acaattgaaa tttacagaat ttaacttatc acaagacatc caatcagctg ttgttaccgc
    17281 tggttttgag aaagcatctc ctatccagga aatgacgatt cctctcgcac tagaagggaa
    17341 ggatgttatt ggtcaagcac aaacaggaac tggtaaaaca gcagcgtttg gtctaccaac
    17401 cttgaataag attcgtacta acgaaaatat catccaagca ttggccattg caccaacgcg
    17461 tgaattggct gtacaaagtc aggaagaatt gttccgtttt ggacgtgaaa aaggggttaa
    17521 ggttcgctct gtttacggtg gatcaagtat tgaaaaacaa atcaaagccc ttaaatcagg
    17581 tgcccacatt gtcgtgggaa caccgggtcg cttgttagat ttgattaagc gcaaggctct
    17641 tattttagat catgtggaaa ccttaatcct tgatgaagca gatgaaatgc ttaacatggg
    17701 attcttggaa gacattgaag ctattattag tcgtgtccca gcagaccgtc aaaccttgct
    17761 cttctccgca acgatgccgg cacctattaa acaaatcggg gttaaattca tgaaagaccc
    17821 tgaacatgtt caaattaaga acaaagaatt aacaaacgtc aatgttgatc aatactatgt
    17881 tcgtgtgaaa gaacaagaaa aatttgatac tatgacccgt ctgatggatg ttaaccagcc
    17941 agaattatcc atcgtttttg ggcggactaa gcgccgagtt gatgaaatta cacgtggctt
    18001 gaaacttcgt ggtttccgtg ctgaaggaat ccatggtgat cttgaccaaa ataaacgctt
    18061 acgtgttatc cgtgatttca aaaacgacca aattgatatt cttgttgcca ctgatgtagc
    18121 agcgcgtggc cttgatattt caggagttac ccacgtttat aactacgata ttacccaaga
    18181 tccagaaagt tatgttcacc gtattggtcg tacaggtcgt gccggtaaat ctggtgagtc
    18241 tatcactttt gtctcaccaa atgagatggg ctacctctca atgattgaga acttaacgaa
    18301 aaaacagatg aaacctctcc gtccagcaac tgctgaagag gcctttcaag ccaagaaaaa
    18361 agtagccctc aagaaaattg aacgcgattt tgcggatgag actattcgtt caaactttga
    18421 taaattcaaa ggcgatgctg tccaattggc tgccgaattc actcctgaag aattagcttt
    18481 atatattttg agcttaacgg ttcaagatcc agatagctta ccagaagttg aaattgcacg
    18541 tgaaaaacca ttaccattca aatatgtggg tggtggtcac ggcaataaaa atggcaaagg
    18601 tggtcgtgga cgtgacaacc gtaaccgtgg tgatcgccgt ggcggctatc gtggtgaccg
    18661 taacagagat gagcgtgata gtgaccgtcg tcgtcaaaaa cgtgataagc gtgatggtca
    18721 cgatggcagt ggcaaccgcg atttcaaacg taaatcaaaa cgtaatagta aagacttttt
    18781 caataaagag aaaaaatcaa gtgctaaaaa tactggtttt gtgattcgtc acaaaggtga
    18841 ataagcttaa agagagttga tgagagtcag ctctttttaa ttttctgaaa aagttgcttt
    18901 tataatggaa tctgttataa tggtttcagt tatttcgtta taatttttaa aaaattagga
    18961 ggagtataag atgtctgata gccatcttac tgcctttgac aaagcttcaa aagcaggttt
    19021 tattattgct ttaggtattg tttatggaga tattggaaca agcccccttt atacgatgca
    19081 gtctctagtt gaaaatcaag gaggggttaa tcaggtttct gaatccttta ttttaggatc
    19141 aatctcttta attatttgga cactgacctt gatcacaaca atcaagtacg ttttgattgc
    19201 tctaaaagcg gataaccacc atgaaggtgg gattttttct ttattcacct tggtacgtaa
    19261 aatgtcaccg tggctcattg ttccggcgat gattggaggt gcaacacttt tgtctgatgg
    19321 ggctcttaca cctgcggtaa cagttacttc agctattgag ggcttgaaag ccgttcctgg
    19381 tctgagtcac atctaccaaa atcaaaccaa tgtcattatc acaactctag tgattttaat
    19441 agtcttgttt ggtattcagc ggtttggaac aggttttatt ggtaaaattt ttggaccagt
    19501 tatgtttatc tggtttagtt ttctaggtgt tagtggtttt tttaatatgt tggggcatct
    19561 ggaaattttc aaggctatca atccttacta tgctctgcat ttgctgttta gtcctgaaaa
    19621 ccatcgtggg atttttatct tggggtccat ttttcttgcg acaacaggag ctgaagccct
    19681 ttattcggat ttaggacatg ttggtcgagg aaatatttat gtgagctggc cctttgttaa
    19741 gatgtgtatt gtgctgtctt actgtggcca ggctgcgtgg attttagcga ataaacactc
    19801 aggtattgaa ctaaaccctt tctttgctag tgtgccatca caattaaggg tttaccttgt
    19861 tagtttggca accttggcag ctattattgc ctcacaggct cttatttcag gctcctttac
    19921 cttggtttca gaagccatgc gtttgaaaat tttccctttg tttcgtgtga cttacccagg
    19981 ggcaaatttg ggacaattgt atattcctgt cattaactgg attttatttg cagtgacctc
    20041 ttgtactgtt ttggctttta gaacatcagc ccacatggag gcagcttatg gtcttgctat
    20101 taccatcacc atgttgatga caacaatcct cttaaagtat tacttaatca agaaaggaac
    20161 gagacccatc ttggctcatt taatgatggc tttctttgcc cttgtagaat tcattttctt
    20221 cttggcttca gctatcaaat ttatgcacgg tggctatgcg gttgttatct tggcacttgc
    20281 aattgtcttt gtcatgttta tctggcatgc gggcacacgg attgttttca agtatgtgaa
    20341 atctcttaat ttgaatgatt acaaggagca gattaaacaa cttcgtgacg acgtttgttt
    20401 tgacctctac caaacaaatg ttgtctacct atccaatcgt atgcaggatc atatgattga
    20461 ccggtctatt ttatactcca ttttagacaa gcggccaaaa cgcgctcaag tttattggtt
    20521 tgtaaatgtc caggtaactg atgaacctta tacagctaag tacaaggtag atatgatggg
    20581 aacggattat atggttcgag tcaaccttta tcttggtttt agaatgccac agactgtgcc
    20641 acgctatttg cgcacgattg ttcaggattt gatggaaagt ggccgtttac ccaaacaaga
    20701 acaggaatat accatcacac ctggtcgtga tgttggtgat tttcgctttg ttttaataga
    20761 agaacgggtc tccaatgcac gtcaattgag taactttgaa cgctttatca tgcagactaa
    20821 ggcaagcatt aaacatgtta ccgctagtcc aatgcgttgg tttgggcttc aatattcaga
    20881 agtaaccctt gaagtggttc ccttgattct atcagatgtc ttgaagttac caatcaaaga
    20941 attggtgcct gtggaagaca gtgaagcata aaaaaatcat tgagatgata agtctcaatg
    21001 atttttcttt tctttttgat gagtagcaat ataggccaat ttctggcttc ttgtttttcg
    21061 ttttttaaag agtgcttcag cgctcatcgc agcctctttg ctatcaaaca cttcgtaata
    21121 aagtaaagaa acaggtaacc ggtagcgagt atatttagcc ccctttcctg cgttatgtgt
    21181 agctaaacgc tttttcaaat cagttgtata accagtgtag agggttttat caacacattc
    21241 taacacatac atataagctt ttttagtggt catgattagg ttttcctttg gaagcagcac
    21301 caaaataaat ctcaaaaata tgatcagtgt attctccgtt ttccttgtgg acaactaaag
    21361 gaggtaaaat agtcatccct tcaatagaac cgtctttgat tgcttcaata agtaacatat
    21421 tagctgattt acctaattta ggatagacaa attgtaccct tttaggggca agaccattag
    21481 ctctaaggct atctataatt tccaagaatc gatctggtcg atgaaccatt gccagacgac
    21541 catttgattt aagggcatga cgggctacct gacaaatttc ttctaaatta gtggtcactt
    21601 catgacgagc cagtaaataa tgttcagaga cgttcttctt agaactttcg tgacttttaa
    21661 agtaaggggg attgcagagc atcaaatcaa ctcctgaacg tggcacatgg tttaggaggt
    21721 tttttaaatc atcacaaatc atggttactt ggtcttccag ttgattgagt tggatagagc
    21781 gttgtcccat atcagcaagc cgttcttgta attctacttc aacgatggct gccttggttc
    21841 tagtgctagc aaataagcca accgccccat ttcctgagca caaatccaca attaaccctt
    21901 tggaaggcat cttggggaag cgggataaga ggacgctatc aatagagtaa ctaaagacat
    21961 ccttgttttg aataatgcca acatcacttg aaaagagttg atcaatacgt tcgccttctt
    22021 ttaagattgc ttttatcata cctgttattt taacataaaa taggcttgag gtgaatgttt
    22081 gaagagtgat tttgactttc gaaaagtcaa ctttcatgat acaataagta agattattct
    22141 attaaaggag aagcctgtgt tttacgctta cttacgcggt ttagtagtct ttttattatg
    22201 ggttgtcaat ggcaatgccc actaccatca tgaagaaaag atgttagatg cttctgagaa
    22261 ttatattctg gtagcacccc atcgaacctt ttgggatcca gtttacatgg catttgcagc
    22321 acgtcctaag cagtttattt ttatggctaa aaaagagttg tttgcaaatc gtctctttgc
    22381 ttggtggatt aaaatgtgtg gtgcttttcc tattgatcgt gacaaaccga gtccagatgc
    22441 tattcgttac cctgttaata tgctcaaaaa gagcaatcgt tctcttctta tgtttccaag
    22501 tggaagtagg cattcgcaag aggtcaaagg aggggtcgct gtgattgcta aaatggctaa
    22561 ggtcaagatt atgccagcag cctatcaggg gcctatgtcg gttaagggat tactagcggg
    22621 agaacgggtt gacatgactt ttgggaatcc cattgacgtc tcagatatta aacgcatgaa
    22681 tgatgaaggg attgctgagg tggcaaaccg tattcaggca gagtttgatc ggatggatga
    22741 cgagttggca cctttccaac caggcaaagc aaggaaccct ttaacttatc tctaccgttt
    22801 accattagga ttggttttgg tggtggtatt attattaacc atgttatttt cctatattgc
    22861 tagttttgtt tggaatccag ataaacatcg ccattaagaa catgagggct aacatgtgtc
    22921 tgaaataaga agtgattgag attagtcttc tattgaaaga agccgctaat gcttaatcac
    22981 ttttttcatt tctaaaaaag atattcgatg atacccttaa ctcttttaag cacaaaaaat
    23041 gacaatacta ctatactttt ggacatcatt tacgaataaa aagatgaggt aaaaaaatgt
    23101 tagacgaatt attaattaaa ggaaaatcgt ttttgagaga gcggtatttt ctgccatacc
    23161 taattagtct tttattagga ctttttctaa tactaagctt cagttttttg ttctggggaa
    23221 ataggcagag caaggcagcc gttcctgctt tgagagaaat atcgcctgtg aaacagcagg
    23281 ttagtgaaga aaaaaaggaa attcaagaag atagcagtat tttagtggat ttaaaaggcg
    23341 ccgtacaaaa agagggagtt tataagctaa ctgctagcag tcgtgtgcga gatgtcattg
    23401 aactagctgg aggcctaact tcagaagctg ataaacatgc tattaatttt gcagaaaaac
    23461 taactgatga gcaagttgtt tatgtaccta aacaaggaga agagatttct gtgctaccaa
    23521 gatcattagt ttctggtaaa aaagaaactg ccagcaagga tcagtcaaag gttcatatta
    23581 ataaggccag cttagaagaa ctacaacata tcccaggtat tggtgctaaa agagctcagg
    23641 atattattga tatgagagat aagttaggtg gttttaaagc gttagaagat ctccgtcagg
    23701 tttcggggat tggcgaaaaa acgctcgaga aattaaaaga tgacattttc ttggactaag
    23761 ctagtgcccc tgtcaaagat tcaatttgct tttttaatct tggttctctt ttatcaaatc
    23821 catagcccta gctggttaac gtttctcctt agccttagtt tgatttgctt acttgtcaag
    23881 cgtttgtcta aaaaagaatt tcttggtgtc tttgccatcc ttagtttctg tgctttgttt
    23941 ttgctgtatc agaaacagca gttgattcaa aaactggaaa ttcagccagt acaaataacc
    24001 tctgtagcat tagttcctga tagtattcgg attaatggtg atcaattagc tgttcttgga
    24061 cgtcacggga aacattctta tcagttattt taccgtttga aaagccaagc agaagcccaa
    24121 ttgttcaaga aagagcaccg ttggttagtg atgcacgcaa aagtgacatt ggaaaaagct
    24181 gaggaagttc gaaattttaa aggctttaat tatcagactt ttttggctta tcaaggaatt
    24241 tacaggatag ggaaggtaga gcaaatagaa cagcttgaag tgatttcacc cgagtcaata
    24301 tgtgactatt tgtcctcttt aagacgacga gccattgttc attgccagca gcattttcca
    24361 agacctatgt ctcactacct gacggacctc ctttttggtt atttagataa gtcgtttggt
    24421 gagatgacag attattatag tcagttgggt atcattcatc tctttgcttt atcagggatg
    24481 caggttggct tctttcttac ttgttttaga agggtgttgc tattactcgc agttcctttg
    24541 gaatggataa aatggataga gcttcctttt gcttgctttt atgccgcgtt gacaggttat
    24601 agtatttctg ttattcgaag cctcgtgcag tcgcagttgc gtcatttagg aataaaagga
    24661 ttagacaatc tggcttgtac ttttttactt gtctttttat gggatgctca tttcttaatg
    24721 actgttggtg gcgtattaac gtttagctat gcttttttgt taacagtggt tactgttgaa
    24781 gaattatcag gagctaaaag acagttggta caagtcttga ccatttccct aggaatatta
    24841 ccatttttgc tcttttattt ttctagtttt aaccccatgt caatggtctt aacagggctc
    24901 ttgtcttatc tctttgacct ttttattttg ccccttcttt gtctggtttt ttgtctatcc
    24961 cctttggtga ctgtctcaat atgtaaccat ctttttattt tattagaaaa agtcattcaa
    25021 tttctcggaa atactttcaa tagttccctt gtttttggaa gcccgaccag ttggcacttg
    25081 cttatcttgg tgattagctt cgctattttt tatgattatc ggcaggtgcg acaacgagtt
    25141 atcacttgcg gtttggttat agcgttgacg cttttgtctg tcaaatatcc tttgaccaat
    25201 gaagtgacct ttatcgacat tggccaggga gatagtattt tggtgaggga gtggacaggg
    25261 aaaaatctct taatagatgt aggtgggcgc cctttctttt cttcaaaaga gcactggcga
    25321 cgaggacatc acgtagctaa tgctcagaaa accttaattc cttacttaaa aagtagaggt
    25381 attcacacaa ttgaccaact attagtaact cacgcagata ctgatcatat gggggatatc
    25441 gaagtggttg ccaaagctat tcggataaag gagattttga ctagtcaagg cagtttaagc
    25501 catccaagct ttgttaggcg gctaaggcgt ttaaaatgtc acgttagggt tttagcagct
    25561 ggagaccagt tgcctattat gggaagtgtc ttacaggtac tctacccttg gcagttaggg
    25621 gacgggaaaa ataacgattc tttggtactt tatggcaggc tcttaaatcg aacttttctt
    25681 ttcacaggtg acttggaaaa agagggggaa aacgagatca taaaacgtta tcctcaacta
    25741 agagtagatt atttaaaagc aggtcaccat ggatcaaata cctcttctag tgcagctttt
    25801 ttagaccata ttcaacctaa agtggccttt atttctgctg gaaaaaataa ccgttatcag
    25861 catcctcaca gagaaacctt agcccgtttg gaagacagac aaattactta ttaccgaacg
    25921 gatacgcaag gagctattcg tttgactggt tggacaagct ggcatcttga aacggtccgt
    25981 tagttaaaat tccagcctga cgaagaaaca agcagtcgct ttccttttag gagaaagatg
    26041 atataataaa agcatgattg cgatagaaaa gattgaaaaa ctgagtaaag aaaatttggg
    26101 tcttataacc cttgtcacag gagatgacat tggtcagtat agccagttga aatcccgctt
    26161 aatggagcag attgcttttg ataaggatga tttggcctat tcttactttg atatgtctga
    26221 ggccgcttat caggatgcag aaatggatct agtgagccta cccttctttg ctgagcagaa
    26281 ggtggtcatt tttgaccatt tgttagatat cacgaccaat aaaaaaagtt tcttaaaaga
    26341 aaaagaccta aaggcctttg aagcctattt agaaaatccc ttagagacta ctcgactaat
    26401 tatctttgct ccaggtaaat tggatagtaa gagacggctt gttaagcttt tgaaacgtga
    26461 tgcccttgtt ttagaagcca accctctgaa agaagcagag ctaagaactt attttcaaaa
    26521 atacagtcat caactgggtt tgggatttga gagtggcgct tttgaacaac tgcttttaaa
    26581 atcaaacgat gattttagtc aaatcatgaa aaacatggct tttttaaaag cctataaaaa
    26641 aacgggaaat attagcctaa ctgatattga gcaagccatt cctaaaagtt tacaagataa
    26701 tatttttgac ttaaccagac ttgtcctagg aggtaaagtt gatgtggcta gagatttgat
    26761 tcatgattta cgcttatcag gggaagatga tattaaatta attgctatta tgttggggca
    26821 atttcgctta tatttacagc ttgccattct tgctaaagaa ggaaaatcag aacagcagct
    26881 tgtaaccagt ttgtcagaga tacttggtcg gcgggttaat ccttaccagg tcaagtatgc
    26941 gttaaaggat tctaggacct tatctcttgc ctttctaaca ggagcggtga aaaccttgat
    27001 tgagacagat taccagataa aaacaggact ttatgagaag agttatctag ttgatattgc
    27061 tctcttaaaa atcatgactc actctcaaaa ataggcgttg gaccgctttc caagagataa
    27121 tcaaattagt tgaaagctct tattttttgc gataagatag acgtatcata aaggaaaaga
    27181 ggacaggaaa atggctatta ttttaccaga acttccatac gcgtatgatg ctcttgaacc
    27241 acagtttgat gcggagacaa tgactcttca tcatgataaa caccatgcca cttatgtcgc
    27301 taataccaat gcggctttag aaaaacaccc agagatcgga gaaaatctgg aggaactatt
    27361 ggcagatgtc actaagattc cagaagatat tcgtcaagcc ttaattaata atggtggcgg
    27421 acacctaaac catgcgcttt tctgggaact attatcacct gaaaaacaag acgtcactcc
    27481 tgatgttgca caagccattg atgatgcttt tgggtcattt gacgccttta aagaacaatt
    27541 tacagcagct gctactggac gttttggttc aggttgggca tggttagttg ttaataaaga
    27601 aggacaactc gaaatcacat caaccgctaa ccaagatact ccaatttcag aaggcaaaaa
    27661 accaattcta gcgcttgatg tgtgggagca tgcttactac ttgaattatc gtaatgtacg
    27721 tccaaattat atcaaagctt tctttgaaat cgttaattgg aaaaaagtat cagaacttta
    27781 ccaagccgct aaataagaaa agggtttcca atctcaaaaa gagattggtt ttttaagtgc
    27841 ttttttgaat aacagtgtgg ggacatcatt ttttagaaaa gataaaaata gtttgtcttt
    27901 ttaatgtaat tccttgattt ttagctaaat ttagctagaa tagaatggat aggagatttt
    27961 aggtgttaag agagaagaaa actaccattg tagggattat tttaggaatg atgatagtga
    28021 ccttacttgt cggctgtttg actggtaaaa agaaaggatt tcctcctaaa gcaggtgagc
    28081 ggcagcaaac ggctgactta aaaatgaaaa aaagattaga aaaactgttc aaaaaccgtt
    28141 acctgaaaaa tctaaagagg ctaagcaagc tgttatggat gcagatttag cgcaaatgga
    28201 tgtcttaggg ctctattacg atgacaacca tttgagtttg gtcaatacgg tcaaggcgta
    28261 tttaaaggaa tttggcattg gtgaatccca aattgccttt tcctacaaag acctcaattc
    28321 aggcaggact gctgccatga atgaccatca gccaatgatt gcaggaagca cctataagct
    28381 gccattaaac atgctggtgg tagataaggc aaattatcca tgacagagcg ttttgacatt
    28441 acagaaactg attatgaata tgatcaggaa catcatgcct atgttgctca attcaatggt
    28501 gccatgtcta ttccggatat gcaagatact cagaaatcac gccagcttat gctctagcag
    28561 aacgattggg tggcatgaat aaggcttacc aattatttga ccgctacggg aaggtatccg
    28621 gggctattac gaccattgat cgtaatggca ataaaatcac caccgcttac tatttgcaag
    28681 ttttggatta cttgtggcag catcaggata aatataagga tatcttgtac tacattggtg
    28741 aatctttccc tgatttgtat tacaagactt atttgcctca tgtaaaggtt tatcaaaaac
    28801 cgggttatgt cagagaagcc ttaaatgtag gtgccattgt ttgcgaagag tctccttatt
    28861 tgattactct ttattcatct ggtttaggtg gagcaacaca agcatcagag gaagtcaatg
    28921 gccttggtta tgtgcagctt gttcagctaa catatgtaat taatgagtgg catagagtca
    28981 atcacaacat gatctaatac tcagttgaca ttagtctgat agtagacata cttactgatg
    29041 aaagtcacta aaataagttt ttgctcatta aaaaagcttg gcctgtttct tcaggtcaag
    29101 ctttttgaga ttaatgctgt gtttttgagg tcttattgtc acctcttgtt tcttgataat
    29161 ggtgaagcaa ttttttgaat tttttaacgg cagcgcgtgt tagctgctta gatgatttgc
    29221 catttctgct gtaaatggga ttgtgcttat ccctttgctg ttctaaatcg ggaactagaa
    29281 aagttgcatc aggactatta attgcttttt caataaaagc cggatcaaaa agcagaatag
    29341 ggtcaatatc aagcagacgg tgcaagtcat cgttttggtt gccataattg aaagaagaac
    29401 cattgacaat actatttcgc gttaggttat caggatctag tgctactaaa aattgtccag
    29461 attctgacaa aataaactct gagtgaaaat gaattaaaat cttatagttg gcttgaggaa
    29521 tattgtctgt atagactgcc tgatgattgc cattagcatc taaaatacta gcaaccttat
    29581 tatggtatct agaagattca taaagagcgt aatcgtcatc ttctagagta gccaaatatt
    29641 tggctaaggc atccgcatcg gttttccctt tattcccata atgtgagcga acccactccg
    29701 tttgctgggt tgatatgagg taacggagtt gatgaatttt ccgattaaaa cggctataag
    29761 gaatgtgttc gagattaaca taataagcct gaatcagggt agataattgg tcccaaaaag
    29821 gatctgttgg cgatagcttt ggacttaatt gtgccaatac ttgctgtgtt tgttttgatt
    29881 gtcctgtcaa ctcgtctggc atctttaaat acgtcaagag cagttgtaac cgtttttgag
    29941 cttcttgagg cgtctgtgcc atctcttctt gttgccaaag cttttgaaag tcaggtgatc
    30001 ctatcaggcg aatgcgacta taaagttgtt cgaaatgata agagtttcct ctaacagcga
    30061 gttgttcaag gtatcctttt tggatggctt tataggacca tccgtcctta tcgagctttc
    30121 gaacataatc aagcaagtcg tggcgtaatt taatagcttc tgaaagctgg agttctcgta
    30181 atttaggata gttttggtaa aaaggtgcca ctaaatcttg ataaagtttg tgttcttttt
    30241 caaaggcaat ccgctgatag tctttctgcc aaaaactgac gcaaaaagtc agaaacatca
    30301 agaagaatag ccattttcca agtaatttca taggttttta gttgacaaac atggcatcgc
    30361 caaagctaaa gaaacgatac ttttcgtcaa ccgcgtgtct gtaagcttca aggacaaagt
    30421 cacgccctgc aaaggctgat actagcatca caagggttga ttttggaaga tggaaattag
    30481 ttgaaaaagc atcaactacc ttgaattggt agcctggttt aataaaaata ttggtccaac
    30541 ctgaatcagc ttgaatgtcc ccttggaact tacctccgat ggtttccaac gtacgaatag
    30601 aggtggttcc tacagcgaca acacgaccgc cagcttgttt gacgtctctt agggtttgcg
    30661 ctgcttcttc tgagagggaa taaaattccg aatgcatatc atgctcatcg aggttatcca
    30721 cggaaacagg tctaaaagtc ccaagcccta catgtagggt caaataaacc aaatgtaccc
    30781 ctttggcttc gatttttttg agcaagtctg ttgtgaagtg gagaccagca gttggggcgg
    30841 ccgcagagcc attttcttta gcataaacgg tttggtatcg ctcagcatcc tctaattttt
    30901 cgtgaatata aggaggcaat ggcatttcgc cgaggctctc taaaacttct aagaaaatcc
    30961 catcatagct gaattcaaca attcgtccac catgttctaa ttcgtcgata atggtggctt
    31021 tgagacgccc atctccaaaa ttgacttggc taccaacctt gagccgtttg gctggcttgg
    31081 ctaaaacttc ccattgatct ccttgtgtat ttttaagcaa aagcaattcc acatgaccat
    31141 gagtatcggg tttttctcca taaagtctgg caggcaagac acgggtatta ttcatgacga
    31201 gggcatcccc tggatttaat tgatcaatga tatggtcaaa atggctatca accatagttt
    31261 tttgacggtg atcaataatc aatagttttg aactgtctct tttttcgagt ggggtttggg
    31321 caatcaattc ttctggtaac tcaaaatcaa aatcgttagt attcattggg actcctttaa
    31381 agccactagt aaatctcttc ctagtaactc tttcatgtaa gataaatctt ttctattata
    31441 tcacttgtcg tctaacccgt catctttaat ctttcatcag aaagtaaagg ataggcttga
    31501 caaaaattgg tatataccat ataataaaaa cacgaaaggt ctataccaat tagaaaagga
    31561 gaatgacatg aaaattattc gggtccaaga tcagattgaa ggtgggaaaa tcgcttttac
    31621 cttattgaaa gatagcttag ctaagggagc taagacgtta ggattagcaa caggaagttc
    31681 accaattagt ttttaccaag aaatggtcaa aagtcctttg gatttttcgg acttaacaag
    31741 tattaacttg gatgaatatg tcggtctttc agtagagagc gatcagagtt atgattattt
    31801 tatgcgtcaa aaccttttta atgcgaagcc ttttaaaaag aattacttgc ccaatggttt
    31861 agcaactgat atcgaagctg aagctaaacg atatgaccaa atcattgcag agcatccgat
    31921 tgattttcaa gtgcttggga ttgggcgtaa tgggcacatt ggttttaacg aacctgggac
    31981 ctcttttgaa gaagaaacgc atgtggtgga tcttcaggaa tcaactatca aagccaatag
    32041 tcgtttcttt acaagtattg aggatgtgcc aaaacaagct atctctatgg gaattgcctc
    32101 catcatgaag tccaaaatga ttgttcttct tgcctttgga caagaaaaag ctgatgcgat
    32161 caagggaatg gtttttggac caatcacaga agacctccca gcaagtattc tccaaaaaca
    32221 tgatcatgtt atcgtcattg tggatgaagc tgctgcgtca caattagatt cacctaacca
    32281 gtcgttaaac cttgtaagaa caaaaatgag gagatagtca acctcattta agaagaagtc
    32341 ttgtaacttc tatttctttt gcaagggtaa atttatgtta cactactaat atgcgtttag
    32401 ataaattatt agaaggtaca aaagttggct ctagaagtca agtgaagaaa ctgattaagg
    32461 ctcaaggggt ttgggttgat cacatgcctg ccagaaatgg tcgacaaaat gttgatcctg
    32521 gcttgcaact gattgaggtg actggacagc gagtgacgca tcctaaacat tcctacatta
    32581 tcctcaacaa gccatcaggg gtggtctcag ctaagaaaga tactaactat ttaaccgtta
    32641 ttgatcagct tgctgaagaa gataaaagtc cagacttgta tcctgttggc agattggata
    32701 gagataccga agggttggtt ttactcactg ataatggtcc cctagggttt cggatgttgc
    32761 accctattca tcatgtttct aaaacgtatc ttgtaaccgt taatggcttg ttagcagaag
    32821 atgcctcaga tttttttgca gctggtattt gtttcccaac aggtgaacaa tgccaaccag
    32881 ctcaattgac tattcttaaa gccgatacag accagtcaca ggctagtttg accatttcag
    32941 aaggaaaatt tcaccaagtg aaaaaaatgt ttttgaccta tggtttgaaa gtgacctctc
    33001 tgaaacggac gcactttgca ggactggaac tcggtcattt agccagcgga gaatatcgtt
    33061 atctaacagc gtcagaaagg caactcatta aaacgtatct ggactgagca aaacatgctt
    33121 tcaaaaagaa gctattcttg cttaatcaat aaagtgtcca ttgactatta tagtcatgat
    33181 gagtccgact tttgctatgt ttagtcatct tgttgttaca aaatcaggta agcaaaaaaa
    33241 ttcaattccc actgtctcct taacctgaag cgttataaaa acccttgtgt taaactctca
    33301 taaattggaa atgggagtgt tttttgatgg ctaaaaaaac taaagctact taaagtttgg
    33361 tacttagttt tcgaataata aggtggaaga tctaatagga ggtgacaaaa atattaaccg
    33421 ctttagatgg taagaatcag ctcatttcgc tagtaactca gcctatttca acgaaaccgc
    33481 cttttcgttg cccagcttgt aaatctcctg ttcgcttgcg tcaggggaca attagacgac
    33541 ctcattttgc ccatgtacaa ctagctcatt gtcaattcca agcagaaaat gaatctgagg
    33601 aacatttgac gttgaaggca aaactttaca ccagtttagt ccgaacagaa gctgtttgta
    33661 ttgaaaaata tcttcctgag ctgcaacaga tagcagacct ttgggtgaat gataagttag
    33721 ccttagaaat tcagtgcagt cccttgccag tggagcgtct aaagaaacgc accaaagcct
    33781 gtcaagaaaa ggggtatccg gtacgatggt tactgggaag aaaattgtgg cttaacactc
    33841 acttaactgc tttgcaaaaa cagtttcttt acttttcatc tagcttgggc tttcatttgt
    33901 gggagctgga tgcagctgca aatctgctac gtctcaaata tttaatccat gaagacttat
    33961 ttggtaaggt aagttaccta accaaaacca tttctttaga ccacaatatt atggaaatgt
    34021 ttcgattacc ctatcagcaa gaaatccttt attcttatca gaaaaaaatg actgtgaacc
    34081 tatctaaaag aatacaaaga gctcttttag ctagacaccc gaaatggcta cgacgacaag
    34141 aaaaggctta cttatcaggc tataatttac ttatgttaac aactgatgct ttttatcctc
    34201 aatggagacc agttcaatct tccagcggtt tttgtcaaat taaaggaaat cttcgccctt
    34261 attatgaaag ttttaaagtc tattataaaa aagaaaagga taagaaggtg caaacgcttt
    34321 tttcaccaaa atattatgtt aaaatggata gtaatagaaa atgagaagga gatgttatga
    34381 ctgataatcg cagccattta gaagaaaaat acacttggga tttgagcact atttttgcaa
    34441 cagataagga ttgggaagct gaagtcagtg acttagctac tgaagttgag gcatctaaag
    34501 gttttgctgg tcatttgctg gattctagtg ctaatttgtt aaaggttaca aaaacatatt
    34561 tagaattggc tcgtcgtgtg gagaaagtct atgtttatgc tcacatgaaa aatgaccaag
    34621 acactactgt tgccaagtat caagaatacc aagctaaggc ttcaggcttg tatgcaaagt
    34681 ttagcgaagt cttttcattc tatgacccag aagttatggc attgagtcag gaagattacc
    34741 aagcttttct tgcggaaaca cctgatttaa aaaggtatca tcatttcttt gacaaattgt
    34801 tccagacacg tgaccatgtg ctcagccagg ctgaagagga attattagca ggagcccaag
    34861 aaattttcaa cggcgctgaa gaaaccttta gtattcttga taacgctgat attgtctttc
    34921 cagtagttaa aaatgataag ggggaagatg ttgaattaac ccatggtaac ttcattagcc
    34981 taatggaatc taaggaccgt agcgttcgcc aagctgctta tgaagccatg tatagtactt
    35041 atgaacagtt ccaacatact tacgctaaaa ccttgcaaac caatgtgaaa gtgcaaaact
    35101 ataaggcgcg tgttcataaa tacgattcag cacgtcaagc tgccatggct gctaacttta
    35161 ttccagaagc tgtttacgac actttattag aaacggttaa caaacattta ccactcttac
    35221 accgttattt gaaattgcgt caagaggttc ttggtttaga cgatttgaag atgtatgatg
    35281 tttacacacc attatctgaa acagatctag ccattggtta tgatgaggct ttggaaaagg
    35341 ctgagaaggt tttagctgtt tttggtaaag attacgcaga tcgtgtgcat cgtgctttta
    35401 ccgaacgttg gattgatgtt catgtcaata aagggaagcg ttctggagct tattcgggtg
    35461 gttcctatga taccaatgcc tttatgctat taaactggca agatacctta gacaatctat
    35521 acactttagt tcatgaaact gggcacagtt tgcattctac tttcactcgt gaaacacagc
    35581 cttatgtgta tggagattac agtattttct tggcagaaat tgcatccaca acgaatgaaa
    35641 atattatgac agaagctctc ttaaatgagg ttcaagatga gaaagaacgc tttgccattt
    35701 taaaccatta cctcgatggt ttccgtggaa cagttttccg tcaaacccaa tttgctgagt
    35761 ttgaacatgc cattcatcaa gctgatcaaa aaggagaagt gttaacaagc gaatacctta
    35821 accagctata cgctgattta aatgaaaaat attatggttt aagtaaaaaa gataatcatt
    35881 ttattcagta tgaatgggca cgtattcctc atttctatta caattattat gtttaccaat
    35941 atgcaacagg ttttgcagct gcaagctatt tagcggataa gattgtgcat ggcacacaag
    36001 acgatatcga tcattacttg gcctacctca agtcaggaaa ttctgattac ccacttgaag
    36061 tgattgctaa agcaggcgtt gatatgacaa aaggtgatta tttggaagcc gcctttaaag
    36121 tctttgacga acgtctaaca gaacttgaag tactcgtgtc caaaggcata cacaaaagct
    36181 aaaatcacaa aagtcaagga caaaaagagt ttaggattga tagaaatgga gattcacagt
    36241 tggtgtgaat ctccatttct atcggtcatt ttctttttat attttagtgg attatcagtc
    36301 ctgaaaagca ggcttcattg accttagttt gacggtttct tttttgtctt ttttattgtg
    36361 tggtcactca cttaaataaa accaatagtt gagtaaggcg cttcagatta acgctattct
    36421 attgctttag agataacgtt cgcataaaac atatttttat tatatttgac attttataaa
    36481 agagataata gaattaaaat actaacattt atgtttttta aaaaataaac gttcgtataa
    36541 taaaaaagga gtttttcatg gaaaaaacaa aacgttatat cattgcaaca gcagggatac
    36601 ttctccactt aatgttggga tcgacctatg cttggagtgt ttatcgtaat ccaattttac
    36661 aagagaccgg ttgggaccaa gctcctgtcg cttttgcctt ttctttagct attttttgtt
    36721 taggtttatc tgctgctttt atgggaaatt tagttgaaca atatggtcct cgtctaaccg
    36781 gaacggtgtc agctattctt tatgcttctg gaaatatgct gactggttta gcgattgatc
    36841 gtaaagaaat ttggctttta tatattggtt atggtgttat tggtggctta ggacttggag
    36901 cgggatatat cacaccgata tcaactatta taaaatggtt tccagataaa agaggcatgg
    36961 caacagggtt tgctattatg gggtttggtt ttgcgtcttt attaacaagt ccgattgccc
    37021 agtggctaat tgaaacagaa ggtttggtag caacatttta ccttttaggg ctgatttatc
    37081 taatagttat gctttttgct tctcaattga taataaaacc aactgctgct gagatagcta
    37141 tactagataa aaaaagatta caaaataaca gttatttaat cgaaggaatg accgctaaag
    37201 aagcacttaa aacaaaatca ttttattgtc tttgggtaat tttatttatc aatatcacat
    37261 gtggcttagg acttatctca gttgttgcgc caatggcaca agatctaact ggtatgagtc
    37321 cagaaatgtc agcaattgtg gttggtgcta tggggatttt taacggtttc ggtcgtttag
    37381 tgtgggctag tttatcagac tatattggac gccgtgtgac agtaatactt ttatttttgg
    37441 taagcataat tatgactatt agtttaatat ttgcacatag ttccctaatt ttcatgataa
    37501 gcattgccac ccttatgact tgttatggtg cgggtttttc tctcattccg ccttatttaa
    37561 gtgatctttt tggggcaaag gaactggcta cattacatgg gtatatattg acagcttggg
    37621 caatagctgc attaactgga cctatgttat tatctatcac tgttgaatgg actcataatt
    37681 atcttcttac cttatgtgtt tttattgtct tatacatttt aggattaatg gtagcattaa
    37741 ggttgaagaa atgatgtcct ataaaaaatt taaaagtaaa ccctagcaaa gcctagggtt
    37801 tttttatata attaggttta tggttaaatc atacagtaaa acagcaaatc ataatatgcg
    37861 tcgtcctgtt gtcaaagaag agcttgttca ttatatgcga acacggcaga agcaaaccac
    37921 acgtttttta gcagagttag agcaattcgc aagacaagaa aacattccta ttattcagcc
    37981 tgaggtcgtg gcttatttta ggtttttatt gcaaagctta cagccaaaac acattttgga
    38041 gattggcaca gccattggtt tttctgcgct tttaatggct gaaaatgcac cagatgcgac
    38101 gattgtgact attgatcgga atagagagat gatcgatttt gctaaagcaa attttgctaa
    38161 gtacgacagt cgccaacaga tccgcctgtt agaaggagat gcagcagata tattatctac
    38221 acttgaagga aattttgact ttgtgtttat ggattccgcc aaatccaaat atattgtctt
    38281 tctaccagag attttcagac tgttaagagt cggtggtgta gtcattttgg atgatgtctt
    38341 tcaaggaggt gacattacaa aaccgatcga agacattcga cgaggtcagc gtactattta
    38401 tcgtggctta cagtctttgt ttgatgccac cttaactcat ccaaacctaa caactagcct
    38461 ggtccctctt agtgatggat tattaatgat tcgtaaaaat caagcagata ttgtattacc
    38521 agattaagta acattgataa atttatgtta taataaatta gttaaagata aaaaggagct
    38581 cagaagtaaa tgaaaaactc aaataaactc attgctagtg ttgtgacatt ggcctcagtg
    38641 atggctttag cagcttgtca atcaactaat gacaatacta aggttatttc gatgaaaggt
    38701 gatacaatta gcgttagtga tttttacaat gaaacaaaaa acacagaagt atcgcaaaaa
    38761 gcgatgctaa atctggtaat tagtcgtgtt tttgaagctc aatatggtga taaggtttca
    38821 aaaaaagaag ttgaaaaggc gtatcataaa acagctgaac agtatggcgc ttcattctct
    38881 gctgctttgg cacaatcaag cttgacacct gagactttta agcgtcagat ccgctcttca
    38941 aaattagtag aatatgcggt taaagaagca gctaaaaaag aattgacaac acaagaatat
    39001 aagaaagcat atgaatctta tactccaaca atggcagtcg aaatgattac tttagataat
    39061 gaagagacag ctaaatcagt cttagaggaa ctaaaagccg aaggcgcaga ctttacagct
    39121 attgctaaag aaaaaacaac aacacctgag aaaaaagtga cctataaatt tgattcaggt
    39181 gcgacaaatg taccgactga tgtcgtaaaa gcggcttcaa gtttgaatga gggtggcata
    39241 tcagacgtta tctcggtttt agatccaact tcttatcaaa agaagtttta cattgttaag
    39301 gtgactaaaa aagcagaaaa aaaatcagat tggcaagaat ataagaaacg tttgaaagct
    39361 atcattatag ctgaaaaatc aaaagatatg aatttccaaa acaaggttat tgcaaatgca
    39421 ttggataaag ctaatgtaaa aattaaagac aaagcttttg ctaatatttt ggcgcaatat
    39481 gcaaatcttg gtcaaaaaac taaagctgca agtgaaagtt caacaaccag cgaatcatca
    39541 aaagctgcag aagagaaccc atcagaatca gagcaaacac agacatcatc agctgaagaa
    39601 ccaactgaga ctgaggctca gacgcaagag ccagctgcac aataagtagg attttattga
    39661 ctaatcagtt aaaaaaactt ataataattt agttaagaat tgtttatcaa ggattagata
    39721 cagaaaagtg acggttgctg cgagtcattg ataattagat aaacatgcta cttaacttta
    39781 caacaattga tatcgtaaat taagaatgac aagttcattg aatagaggtg gtaccgcggt
    39841 tttcgccctc tgtgagatgg acttgttttg tattgaggac tatttgaaat caacgaaagg
    39901 aatagagtag actaggctgc caggcttata gctgatctcc tagcaagaaa gacgagctgt
    39961 gtcaactggt gtgattacat tactagcttc agcataacac tgtttttctt actctttgta
    40021 tctaaatttt tatgaaagaa ttatcgtctg cacaaatacg ccaaatgtgg ttggatttct
    40081 ggaaatctaa aggacattgc gttgagcctt cagctaactt ggttcctgtg aatgacccaa
    40141 cgcttctttg gatcaactca ggtgttgcaa ccttgaaaaa atactttgat ggttcagtga
    40201 ttccagaaaa tccacgtatt accaatgcac aaaaatcaat tcgtactaat gatattgaaa
    40261 atgttggtaa aacagcacgt caccatacta tgtttgaaat gcttggtaac ttctcaattg
    40321 gagactattt ccgtgatgaa gctattgagt ggggatttga actcttgaca agtccaggct
    40381 ggtttgattt ccctaaagat aagctctaca tgacttatta cccagatgac aaggattcgt
    40441 ataaccgttg gattgcttgt ggcgttgaac caagtcactt ggtgccgatc gaggataact
    40501 tctgggaaat cggtgctggt ccttcaggtc cagatacgga gattttcttc gatcgtggtg
    40561 aagatttcga tccagaaaat atcggacttc gcctcttggc tgaagatatc gaaaacgatc
    40621 gttacatcga aatctggaac atcgttctct cacaattcaa tgctgaccca gccgtaccac
    40681 gttcagaata caaagaatta ccaaacaaaa acattgatac aggtgctggt cttgaacgtc
    40741 ttgcagctgt tatgcaaggg gcaaaaacaa actttgaaac tgaccttttc atgccaatca
    40801 tccgtgaagt agagaagttg tcaggtaaaa cttataatcc agatggcgac aacatgagtt
    40861 tcaaggttat cgctgaccac atccgtgcgc tttcatttgc tatcggtgat ggtgcgcttc
    40921 ctggaaatga aggtcgtggt tacgttcttc gtcgtcttct ccgtcgtgct gttatgcatg
    40981 gtcgtcgtct tggcatcaac gaaactttcc tttacaaatt ggttccgact gttggacaaa
    41041 tcatggaaag ctactaccca gaagtgcttg aaaaacgtga ttttatcgag aaaatcgtta
    41101 aacgtgagga agaaacattt gctcgtacta tcgatgcagg tagcggtcac ttagattcat
    41161 tgcttgcgca gcttaaggct gaaggtaagg atactcttga aggtaaagat atcttcaaac
    41221 tttatgatac ttatggattc ccggttgaat tgacagagga attggcagaa gatgcaggct
    41281 acaagattga tcacgaaggc tttaagtcag ccatgaaaga acaacaagac cgtgcgcgtt
    41341 cagctgttgt taagggtggt tcaatgggga tgcaaaatga aaccctagct ggtattgttg
    41401 aagaatcacg attcgaatac gacacatata gtcttgaatc aagtctttca gtcatcatcg
    41461 ctgataatga acgtaccgaa gctgtttcag aaggtcaagc tcttcttgtc tttgctcaaa
    41521 caccattcta tgctgaaatg ggtggacagg ttgctgacac aggtagaatc aaaaatgata
    41581 agggtgacac agttgctgag gttgttgatg ttcaaaaagc accaaatggt caacctctac
    41641 acactgtaaa cgttttggca tcactttcag ttggaacaaa ctacacactt gaaatcaaca
    41701 aagagcgtcg tttggctgtt gagaaaaacc acacagcaac tcacttgctc catgcagccc
    41761 ttcacaatgt tatcggtgaa cacgcaactc aggctggttc attgaacgaa gaagaattct
    41821 tgcgctttga ttttactcac tttgaagcag taagcaatga ggaacttcgt cacattgaac
    41881 aagaagttaa tgagcaaatt tggaacgctc ttacgatcac aacgactgaa actgacgttg
    41941 aaaccgcaaa agagatggga gcaatggcac tttttggtga gaaatatggt aaagtggttc
    42001 gtgtggttca aattggtaat tattctgttg aactttgtgg tggaactcac ttaaataatt
    42061 cttcagaaat cggtctcttc aagattgtca aagaagaagg tattggttca ggcactcgtc
    42121 gtattattgc agttactggt agacaagctt ttgaagctta tcgtaaccaa gaggatgccc
    42181 taaaagagat cgctgctact gtaaaagctc cgcaattgaa agatgcagca gctaaagtac
    42241 aagctcttag cgactcactt cgtgatcttc aaaaagaaaa tgcagagctt aaagaaaaag
    42301 cagcagctgc agcagctggt gatgtcttta aagatgttca agaagctaag ggcgtgcgct
    42361 tcattgctag tcaagttgat gttgcagatg caggggcact tcgtacattt gctgataact
    42421 ggaaacaaaa agactactct gatgtgcttg ttctcgtagc agctattggt gagaaggtta
    42481 atgtccttgt tgcaagcaaa actaaagatg tccacgctgg taacatgatc aaagaattgg
    42541 caccaattgt agcaggtcgt ggtggaggta aaccagacat ggctatggca ggtggtagcg
    42601 atgcaagtaa aattgcagag ctgctagcag cagttgctga aacagtgtaa atccataaaa
    42661 aaccaagtta tttagaactt ggttttttat atttgaaatg actaccatca taaccttttt
    42721 gactattatc gttgtcaaaa agaaaaagat atgttacaat tatagtaaca aatagacatg
    42781 aggaggtgtt agagaaaatg acacatggta tcaaacttaa gaggcagatt tgcttatggg
    42841 caagtatcct gactcttttc attttaagtt atcatcttat cagggtaatc tggtttggag
    42901 tacccttgag ttatctggtt ttgggcttta caggactagc cttgctgttg aatacttttt
    42961 cttattttag aaagtaagtt ataagttaaa gaagaatgaa ggagatggca atggaggtta
    43021 ttcttaaaaa tcggctcaaa gaattacgag ccagagatgg aattaatcaa acggaaatgg
    43081 ctaaactggc aggagtatcg aggcagacca tcagtctcat tgagcgtaac gagtacaccc
    43141 catcagttat aattgccatg aaaattgcaa aggtatttca ggaaccagtt gaagaggtgt
    43201 ttcgtctagt ggaggtcgag gaatgaaaaa gaagaagaat agttttttac gcttgttaaa
    43261 aatgttattg ctatcaagtt tggcgggagg gattataggt ggcatggttg gagccttttt
    43321 aggttaccat ggagagagat tagatcagct cacgttccta aaagatgatg tgattaacct
    43381 gattatctta ttaaatcgtc tagtagttgt cacaggcctc acactttcct ttgttttttt
    43441 aacgcaactg aaaaaagaga cagctgttta taacacaatt gaagaggatg attattctga
    43501 aaatggttac cgtcagctga ataaaaagca tgcttatacc atgttattga ttgccgtagc
    43561 ttctatttta tccatgtgca atgtgctact tggtctgacc ttaactaatg attcacagca
    43621 tgccatgctg gccattccgc ttctggatat ctttttatta ttaatggtca ttccttttca
    43681 agctttagcc atgaaacgtt acaatgccat tcggggaacc gatgttcctt attttccaaa
    43741 tttgaaagaa ttaaaacata atatcatggc tctagatgag gcagagttac aagcctatca
    43801 taagacatcg tttgaaagtg tgttgtcatt aaatggagtc atcatccctt ccttgtatgt
    43861 gattttattt tttgtctatc tattcactga tcaagtggag ttaacagcca tcttagtttt
    43921 ggtgttaatt cagctctatt tactcgttaa gagtgcaaca atgaccagac aattttaccg
    43981 ttagcctaaa aggagactgt ttatgaaagg attcattaat tatttaaaaa tagcagtgct
    44041 cattattctg gctatggttt tcaatgtcct tccgatgatt ttattgcaaa agcaacacga
    44101 tattcctatg gtgcttaatt ggggaattgg tattttctac ttggttattg ttggaagtgt
    44161 ccttattgta ttatggcgtc tttatcaagc taagcaagac acccctatta aacagcaaaa
    44221 aatgagattg gttgactggg gttatttagc attattttgg ttaatcatcc gtgtgatagc
    44281 tattgtaggt acccttgtta accagctatg gtctggtcaa caagtgagtg ctaatgatgc
    44341 tgcaatacat accttagcta gacttatcaa aggtggtttc ccgctttata ctgccctatt
    44401 tgtacttgtg atagctttta tcgctcctat tatggaagaa ctagtcttta gaggatttcc
    44461 tatgattgat cttttcaaag gaaaatcact taaggtggca ggtttagtga cctctcttgt
    44521 ttttgcttta ccacatgcca ccaatagtgt tgaatttatc atgtacagct gtatgggcat
    44581 ttttctcttt gttgcctatc aaagacgagg aaacttaaaa gacgctatct tgttacatat
    44641 ttttaataac ttgattgaag tcattttgtt aatgtcaata ggcttaggag tcatataata
    44701 aaaagcttcg gatggatgaa ctgcacccca aaagttggac aaaaaaatct aacatttggg
    44761 ttggaattgt caagaaaaaa tagacataaa gttaagctaa tgagtaacta tttttttcaa
    44821 attcaacagg tgagagatac cctaaagctg aatgcagacg tttggggtta tagtaagtct
    44881 cactatattt aaaaatctca agcttagctt gctcaatagt tgcgaaatga gcatcattga
    44941 caagctctct ttttaatgtt ttataaaagg attccatgag tgcattatcg tatggattac
    45001 cttttcgact catcctggac ttacattttt tccgtctaag taggtcctga aattgtgctc
    45061 cggtatattg agaaccctga tctgtatgga cgattccccc ttctttaggc ttttctctat
    45121 tataagcttg attgaaagct tctgttacca acttgtcttg catacgttag cccattgccc
    45181 aaccaacaac ctttctacta taaacgtcta tcaagacaga cacataaagt attccttctt
    45241 gtgtaggaat gtaggttagg tctcctagcc ataatttatt cttaccagtc gcttggaaac
    45301 attgattaac aagattggga cgagttcatg aagaacgtcg acggttatag tatttatatt
    45361 gatatcgact tcctttagca tagagaccta gctgatgaag gagtctacca acacgtttat
    45421 aattgacatg gatgccacgt ctacaaagtt cttgggtaat tcgtacactt ccgtaacgct
    45481 ctttatgttc atagaaaatg gctttaatca tttcctt
//
LOCUS       DAUNLR010000008        44571 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUNLR010000008 DAUNLR010000000
VERSION     DAUNLR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44571
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.008"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            161..1393
                     /locus_tag="VLL59_000442"
     CDS             161..1393
                     /locus_tag="VLL59_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HER6508591.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMQKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFAGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKSIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            1561..2742
                     /locus_tag="VLL59_000443"
     CDS             1561..2742
                     /locus_tag="VLL59_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HER6508592.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDIMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSSKQQHFKATKKQSYLERVEDFINHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(2894..4312)
                     /gene="sufB"
                     /locus_tag="VLL59_000444"
     CDS             complement(2894..4312)
                     /gene="sufB"
                     /locus_tag="VLL59_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HER6508593.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKTEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(4305..4784)
                     /locus_tag="VLL59_000445"
     CDS             complement(4305..4784)
                     /locus_tag="VLL59_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HER6508594.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(4771..5997)
                     /locus_tag="VLL59_000446"
     CDS             complement(4771..5997)
                     /locus_tag="VLL59_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HER6508595.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAIFYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(6028..7290)
                     /gene="sufD"
                     /locus_tag="VLL59_000447"
     CDS             complement(6028..7290)
                     /gene="sufD"
                     /locus_tag="VLL59_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HER6508596.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSGVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(7384..8154)
                     /gene="sufC"
                     /locus_tag="VLL59_000448"
     CDS             complement(7384..8154)
                     /gene="sufC"
                     /locus_tag="VLL59_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HER6508597.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYIIPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(8276..9445)
                     /locus_tag="VLL59_000449"
     CDS             complement(8276..9445)
                     /locus_tag="VLL59_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HER6508598.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(9452..10213)
                     /gene="mecA"
                     /locus_tag="VLL59_000450"
     CDS             complement(9452..10213)
                     /gene="mecA"
                     /locus_tag="VLL59_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HER6508599.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(10359..11198)
                     /locus_tag="VLL59_000451"
     CDS             complement(10359..11198)
                     /locus_tag="VLL59_000451"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HER6508600.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(11264..13189)
                     /locus_tag="VLL59_000452"
     CDS             complement(11264..13189)
                     /locus_tag="VLL59_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HER6508601.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRAGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGEEPV
                     DVSTSKKNKIVALETKISRRRALLQLLFGKVIPLVEVGFLLWQLIQFIRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLVLNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFLSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            13387..14955
                     /locus_tag="VLL59_000453"
     CDS             13387..14955
                     /locus_tag="VLL59_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HER6508602.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESYAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVIKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRHIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            14948..15688
                     /locus_tag="VLL59_000454"
     CDS             14948..15688
                     /locus_tag="VLL59_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HER6508603.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     IAEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            15830..15946
                     /locus_tag="VLL59_000455"
     CDS             15830..15946
                     /locus_tag="VLL59_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HER6508604.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(16172..17182)
                     /gene="gap"
                     /locus_tag="VLL59_000456"
     CDS             complement(16172..17182)
                     /gene="gap"
                     /locus_tag="VLL59_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HER6508605.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(17530..19608)
                     /gene="fusA"
                     /locus_tag="VLL59_000457"
     CDS             complement(17530..19608)
                     /gene="fusA"
                     /locus_tag="VLL59_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HER6508606.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(19975..20445)
                     /gene="rpsG"
                     /locus_tag="VLL59_000458"
     CDS             complement(19975..20445)
                     /gene="rpsG"
                     /locus_tag="VLL59_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HER6508607.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(20466..20879)
                     /gene="rpsL"
                     /locus_tag="VLL59_000459"
     CDS             complement(20466..20879)
                     /gene="rpsL"
                     /locus_tag="VLL59_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HER6508608.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(21087..23708)
                     /locus_tag="VLL59_000460"
     CDS             complement(21087..23708)
                     /locus_tag="VLL59_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HER6508609.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASSTHDDSLPKPETTQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQETLAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPSLTGVKLLSYSKVETTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESR"
     gene            complement(23699..24538)
                     /gene="purR"
                     /locus_tag="VLL59_000461"
     CDS             complement(23699..24538)
                     /gene="purR"
                     /locus_tag="VLL59_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HER6508610.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(24805..25743)
                     /locus_tag="VLL59_000462"
     CDS             complement(24805..25743)
                     /locus_tag="VLL59_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HER6508611.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVEEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(25733..27004)
                     /locus_tag="VLL59_000463"
     CDS             complement(25733..27004)
                     /locus_tag="VLL59_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HER6508612.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEKINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            complement(27006..27638)
                     /locus_tag="VLL59_000464"
     CDS             complement(27006..27638)
                     /locus_tag="VLL59_000464"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HER6508613.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGAA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(27631..28293)
                     /locus_tag="VLL59_000465"
     CDS             complement(27631..28293)
                     /locus_tag="VLL59_000465"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HER6508614.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(28303..29175)
                     /gene="rsgA"
                     /locus_tag="VLL59_000466"
     CDS             complement(28303..29175)
                     /gene="rsgA"
                     /locus_tag="VLL59_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HER6508615.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALEMGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(29597..30469)
                     /gene="rsmA"
                     /locus_tag="VLL59_000467"
     CDS             complement(29597..30469)
                     /gene="rsmA"
                     /locus_tag="VLL59_000467"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HER6508616.1"
                     /translation="MRIADYSVTKAVLDRHGFTLKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(30583..31173)
                     /gene="rnmV"
                     /locus_tag="VLL59_000468"
     CDS             complement(30583..31173)
                     /gene="rnmV"
                     /locus_tag="VLL59_000468"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HER6508617.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEATPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(31145..31936)
                     /locus_tag="VLL59_000469"
     CDS             complement(31145..31936)
                     /locus_tag="VLL59_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HER6508618.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQTTISGALALADQYPNVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKETTANAKRVFKLD"
     gene            32221..33051
                     /locus_tag="VLL59_000470"
     CDS             32221..33051
                     /locus_tag="VLL59_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HER6508619.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDSSERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            complement(33162..34100)
                     /locus_tag="VLL59_000471"
     CDS             complement(33162..34100)
                     /locus_tag="VLL59_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HER6508620.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKNEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITPEKIENNLASS"
     gene            complement(34122..35036)
                     /locus_tag="VLL59_000472"
     CDS             complement(34122..35036)
                     /locus_tag="VLL59_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HER6508621.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIVDKDLEKAKTFQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(35048..35710)
                     /locus_tag="VLL59_000473"
     CDS             complement(35048..35710)
                     /locus_tag="VLL59_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HER6508622.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLSVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLFNTYSSYFKHYFKSGLRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLAVILFLYAYPQAVKRDLSLSTLFKRSFLLAGLFFP
                     WSFAFLALICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(35867..36697)
                     /locus_tag="VLL59_000474"
     CDS             complement(35867..36697)
                     /locus_tag="VLL59_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HER6508623.1"
                     /translation="MTKKKLTASDILTTVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(36710..37597)
                     /locus_tag="VLL59_000475"
     CDS             complement(36710..37597)
                     /locus_tag="VLL59_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HER6508624.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMLQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTFGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(37702..39021)
                     /locus_tag="VLL59_000476"
     CDS             complement(37702..39021)
                     /locus_tag="VLL59_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HER6508625.1"
                     /translation="MNMKKLASLAMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(39070..39774)
                     /locus_tag="VLL59_000477"
     CDS             complement(39070..39774)
                     /locus_tag="VLL59_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HER6508626.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLMAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVSLIEVLCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            complement(40048..40182)
                     /gene="rpmH"
                     /locus_tag="VLL59_000478"
     CDS             complement(40048..40182)
                     /gene="rpmH"
                     /locus_tag="VLL59_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HER6508627.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(40497..41411)
                     /locus_tag="VLL59_000479"
     CDS             complement(40497..41411)
                     /locus_tag="VLL59_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HER6508628.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKNAPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTERKAQQPSIPVEESEVPQDADNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(41423..42250)
                     /locus_tag="VLL59_000480"
     CDS             complement(41423..42250)
                     /locus_tag="VLL59_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HER6508629.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(42216..42575)
                     /gene="rnpA"
                     /locus_tag="VLL59_000481"
     CDS             complement(42216..42575)
                     /gene="rnpA"
                     /locus_tag="VLL59_000481"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HER6508630.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            complement(43115..43855)
                     /locus_tag="VLL59_000482"
     CDS             complement(43115..43855)
                     /locus_tag="VLL59_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6508631.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(43859..>44571)
                     /locus_tag="VLL59_000483"
     CDS             complement(43859..>44571)
                     /locus_tag="VLL59_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HER6508632.1"
                     /translation="IYLAIFIWVIVKLDRFAKDQLSQKLTQAQNERIAYLENYNQSIE
                     QLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQQSATSMMRTNYEISSLD
                     NIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLIDLIVLFTGLVDNAIETA
                     KGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQQQNSAHFLTVLDSYPQI
                     TLSTKSDHYRLRQLLEMR"
BASE COUNT        13336 a         9541 c         8124 g        13570 t
ORIGIN      
        1 tacactcctt ttttaatgag gtttcaatta gtttaataaa aattgtcatt ctctcatagt
       61 agcgttttat tacatcacta ctcttgtgag gtaagtcatt accttagaca aaaatatggt
      121 ataattaaaa aaataatact tgagtaagga taatctataa atgatcaaac gattaatttc
      181 cctagtggtc atcgccttat tttttgcagc aagcactgtt agcggtgaag agtattcggt
      241 aactgctaag catgcgattg ccgttgacct tgaaagtggc aaagttttat acgaaaaaga
      301 tgctaaagaa gttgtcccag tcgcctcagt cagtaagctc ttgacaacct atctggttta
      361 caaagaagtt tctaagggca agctaaattg ggatagtcct gtaactattt ctaactaccc
      421 ttatgaactc actacaaact atactattag taacgttcct cttgataaga gaaaatatac
      481 cgttaaagaa cttttaagtg cgttagttgt taataacgcc aatagccccg ctattgcttt
      541 agctgaaaaa ataggcggaa ccgaacccaa atttgttgac aaaatgcaaa aacaattaag
      601 acaatggggc atttccgatg caaaggtcgt caattcaact ggcttaacta accatttttt
      661 aggagctaat acttatccta atacagaacc agatgatgaa aattgttttt gcgccactga
      721 tttagctatt attgccaggc atctcttatt agaatttcca gaagtactga aattatctag
      781 caaatcctcc actatttttg ctggacaaac catttacagt tataattaca tgcttaaagg
      841 catgccttgt tatcgagaag gcgtggatgg tctttttgtt ggttattcta aaaaagccgg
      901 tgcttctttt gtagctacta gtgtcgaaaa tcaaatgagg gttattacag tagttttaaa
      961 tgctgatcaa agccacgagg atgatttagc tatatttaaa acaaccaatc aattgttgca
     1021 gtacctttta attaattttc aaaaagtcca gttaattgaa aataataaac cagtaaaaac
     1081 gttatctgtc ttagacagtc ctgaaaaaac tgtcaaactt gtagcccaaa atagtttatt
     1141 ttttatcaaa tcaatacata caaagaccaa aaataccgtc catattacta agaaatcatc
     1201 cacaatgatc gcacctctat caaagggaca agtcttaggt agagcaaccc ttcaagacaa
     1261 acatcttatt ggacaaggtt atctggatac tcctccttca atcaatctta tccttcaaaa
     1321 aaacatttct aaaagtttct ttttaaaggt ctggtggaac cgttttgtga ggtatgtcaa
     1381 tacctcttta tagaataaca caatgccttt tgtatgacat tgactgacag agtacttctg
     1441 cagtcttttt catttttatt taagcaaact aggctaatcc taacaatttt tcaaaaaaac
     1501 ttcacattgt attagcaaag tgatatactg aaaatgcatt acatttaaag gagtcggaaa
     1561 ttgaccaaaa gaattatact aactattttt acctttattt gcttttcgat gatgcctctt
     1621 gtccacgccg aagatatcat ggatattaca aggcaagcag gctacacagt tagtgaggtt
     1681 aatcgaccaa aatcttctat tgtcgttgat gcaaatagtt cagatattct ttggcaagat
     1741 aatattgata ttcctaggga tcctgctagt atgtctaaaa tgtttacgct ttacatttta
     1801 tttgaagagc tcgctaaggg aaaaattacg atggacacta ctattacggc aactccaacc
     1861 gatcaagcta tcgctaacat ttatgagatt agcaataata atatcgtcgc tggagtagct
     1921 tatcctattc gtgatcttat tactatgaca gctgtgcctt catcaaatgc agcaactgtt
     1981 atgattgcca attatttatc aaacaatgat gcttctgcgt ttatcgatcg tattaatgcc
     2041 acagccaaac aattaggcat gactaacact catttttcaa acgctagtgg tgcagcagca
     2101 caagcttttc aaggttatta taatcctact aaatatgatt tatctgcttc aaatattacg
     2161 accgctcgag atttgtccaa gttactctat gccttcttaa aaaaataccc tgaaattatc
     2221 tcctttacaa ataaatctgt tgtgcacact atggtaggaa cgccatatga agaagaattt
     2281 cacacctata accactctct cccagataat caatttggta tgaaaggagt tgatggatta
     2341 aaaacaggtt ctagtcccag tgctgctttt aacgccatga taactgccaa aagaggcaaa
     2401 actcgactca ttactattgt catgggggtc ggagattggt cagatcaaaa cggggagttt
     2461 tatagacatc ctttcgtcaa tgccttgact gagaaagggt ttaaagatag taagacctta
     2521 tccaaaaaag cacgccaaaa actcgaaaaa ttagtgccac aaaccaaaaa agaaacatca
     2581 tctaaacagc agcacttcaa agccactaaa aagcaatcct acttggaaag agtcgaagat
     2641 tttataaatc acaaccacac tttcttgctt atttgcttag ctatctttat aattactatc
     2701 cttttactaa gcctcgttgt ctttgcaatg ggacgccaat aatgaattat caaaaacctc
     2761 tgtcaaagca cagaggtttt tgatatgtta tcttacgtgt ttaaggcaac taaaaactaa
     2821 ccacttgggg ttagtactac aactcataaa atcctatctc aaagatcttt cagatggata
     2881 agagaaaatg caattaaccg acagaacctt ccatctcata ggaaatcaat cgattgagtt
     2941 cgaccgcgta ttccattggc aattctttgg taaaaggctc cacaaatccc atgacaatca
     3001 tctctgtggc ttcgctttct gataagccac ggctcatgag atagtagagt tgttcttcag
     3061 aaatcttaga cactttggct tcatgttcta acgccacctg tgaattatga atttcgttaa
     3121 atgggatcgt atctgattta gaaatatcgt ccatcaaaat agtatcacat tcaatatggg
     3181 aaacggattt tttagattgc ttgttaaagg tcacttggcc acgataatct actttaccac
     3241 cagacttggc aattgatttt gacacaattg atgatgatgt atgtggagca ttgtgaatca
     3301 ttttagcccc tgtatcttgg tgttggcctg cgttagcaaa ggcaatagac agcatggtgc
     3361 cacgcgcacc tggcccatca agataaacag aagggtactt catggtggtt ttagctccta
     3421 gattgccatc aatccattcc actgttgcat ccgtaagggc gcgtgcacgt tttgttacta
     3481 gattatacac attgtctgac cagttttgaa tggtggtata acgcatgtat gcaccgtcaa
     3541 gcgcaaagat ttcaacgata gcagcatgta agctgttact tgaataagtg ggagctgtac
     3601 atccttcaac ataatgaaca cttgctcctt catcaacaat aatcaatgtc cgctcaaatt
     3661 gaccagtatt ttcattgtta atgcggaaat aagtttgcaa agggatatct actttgaccc
     3721 ctttaggaac ataaataaag gtaccaccag accaaactgc tgaattgagg gctgctaatt
     3781 tgttgtctgt tggcggaacc agtttggcaa agtattgttt gaacaaatca ggatattctt
     3841 tgagggcgga atcggtatct gtaaagataa tccctagctt ttcaaattca cccttcatgt
     3901 tatggtaaac cacttctgac tcatactgag ctgatgcccc agcaagataa gcacgttctg
     3961 cttctggaat tccaatacga tcaaaggttt cttttatttt ttctggaaca tcatcccaag
     4021 aacgagctgg cttatcagat gctttttgat agtaaatgat atcatcaaag ttaatatctg
     4081 ataagtctgc tccccaggtt tgcatcggca ttttattaaa ggtttccaag gattttaaac
     4141 gaaactccaa catccactca ggttcagttt tggcagctga tagttcgcga accactgcct
     4201 cactcaatcc ttttcctgta gaataaatgg gctctacatc atcgtgaaat ccaaattggt
     4261 agtcccctaa gtcaattggc tttggctcta ctttctcatt tatatcagac atttttccct
     4321 tcctttacat tttggtccgt gaggtgctga gcattggcac ttcgtttaat ggcttccttg
     4381 agagcattcc aagctagggt agagcatttg atacgctgtg gaaattttgc aactcctgcc
     4441 aacaattctg cttcacctag ctctttttga gcaggatttt cctgtccttg taccatctct
     4501 gaaaaaatat cagctaacgc gagtgcttct tctttacttt taccaataac agcatctgtc
     4561 atcatgcttg atgaagctgt ggaaatggta cagccgttgc ctgcaaaagc aatatcttca
     4621 attttatctt cgtcaaactt aacggtcaaa gaaatcacat caccacaagt cggattattc
     4681 agttgaacag cctctacgcc atctagttgc ccatgatgat gtggacgttt cgaatggtcc
     4741 gctaccacag ccatgtatag atggttcagt ttagagagtg ccattgaaaa actcctttgc
     4801 ttttagaatt gcttcgacta gacggtcaca atctgccttg gtgttataga tataaaaact
     4861 tgctctaaca gttgctggta cacctaaata actaagaaga ggttgggcgc agtggtgccc
     4921 tgctcttact gcaacacctt catagtccaa ggctgttgcc aagtcatgag gatgcaaatc
     4981 atccagatta aaagaaatca gaccagatct tgcactaggc tggcttggtc catatatggt
     5041 aagcccctca atagcttcta atttcggcaa gacataggct attagttctg cttcatgcgc
     5101 atgtatatca gccatgccta gtctctgaag gtaaaaaatg gctgcgctta gcccaatagc
     5161 accagctatg tgaggtgttc ctgcttcaaa cttccagggc aattctttcc aagtggcctc
     5221 ttgttcgtaa acaaaatcaa tcatttctcc gccaaattca agaggctcca cttgattcaa
     5281 aagctcttct ttgccgtaaa gaacacccaa acctgttggc cccaacatct tatgagctga
     5341 aaaagcaaag aaatcacaat ccaagtcttg aacatcaata gccaaatgtg gaaccgactg
     5401 ggcaccgtca acaacaaggt aggctccttt agcatgtgcc agcttggcaa tttctttaat
     5461 gggattgatg caaccaagaa cattggagac atgtactagg ctaacaaaac gtgtttttgt
     5521 cgtcaatttg tttgccaaat cgtccatgtc aagttggcca tcttttaaat aaacatagac
     5581 taaccttgct cctgtttttt gacaggcttg ttgccaagga atgatattgg catgatgctc
     5641 cataatcgaa atcaacacct catcttctgg cgtcaagacc tgctctgcaa accgagcaac
     5701 ccaattcaaa ctggttgttg ttcctctggt aaagagcact tccttacttg atttagcatg
     5761 aataaagtca gcaacctgct ggcgactggc ctcatatttg tgcgttgcac gttcagccaa
     5821 ggtatgaact cctcggtgga cattagcatt atcttcttga taataggatt gcaaagcctc
     5881 aagaacaagc gccggttttt gtgtggtggc ggcattatcc aaataaacaa ggggttcatc
     5941 attgacttgt tgatttaaga tttgaaagtc ttgtttgatg tcttttgcgt ctagcaatac
     6001 taacctcttt ctttttggca gtaggtctta acgattaagc aatttctcat ctaaaacctt
     6061 aataatctct tggcggactg atggaatagg aatttcagcg ataaccgctc ctaggaatcc
     6121 tctaataacc aatcgttctg ctgtttcttg atccagtcct cgactcatca agtaatacat
     6181 atcttcaggg tcaacctgac cgatagaagc tgcatgacct gctgttactt cattttcatc
     6241 aattaagagg attggattgg catcggctct tgcttggtca gaaagcatca aaacacggct
     6301 ttcttgttga gcatcagctc ccttagcgcc ttttagaata tgaccaatcc cgttaaacgt
     6361 taaggtgcca cgttccaaaa tcacaccatg ctgtaaaata tgaccgaccg tacgttgacc
     6421 atagttggtc acgcgcgtgt caataccttg tacctgacga ccacttgagg ctgcaacaac
     6481 tttcaaatca gcttgtgagc cctgaccaat caaatcactg tcaaaatcag caatgacatt
     6541 gccttcattc atcacagcta aggcccaatc aatgttggca tccttctcta aacgtcctcg
     6601 acggctaata taggttgtca ctgaaggacc taagcggtcg atagccgaga atttaatctg
     6661 gctgcctgct tgagcaatca cttctacact gatattagcg ctggtctttt gagtggcatt
     6721 gccaatagat tcaaaacgct ctaaataggt gaacttactt tcttttcctg caatcactag
     6781 aacatgcttg ttaaaaggaa cgccactgtc actatcttgt aagaaaatag cttcaatagg
     6841 agttgtgatt tccaagtgat caggaacgta gagcacggct gcgctattaa aataagcagt
     6901 gtggtaggca gctagtttgt cttcatcaaa agctaatgcc tgaccaaaat gagcttcaat
     6961 tacttctggg atttcctcaa gcgccgtata aaaatcactg aaaacaactc ccttgtcaat
     7021 taacgccatt ggtaactgtt ctaagactgt ttgcgtgcct acctgaacaa gctttgggtt
     7081 atctccaata gctataaaat ctggaacact agctagactt tcattttctg ttaaggtacc
     7141 atctcctaga ttccaacggt gaaatttaac cctttcgatg gttggtaatt ccaaatttgg
     7201 aatggcttct aatgccgcta aacgccgttc ttgcagccaa gcaggctcag cgtgggcttg
     7261 cgaaaaagcc actagttttt cttttgtcat ctgtcaatcc tttgtctctg gtttttaaat
     7321 tggctgggta ttagaacatc acctagcttt ttgtagaaag ctaaagtaat tgtctccaaa
     7381 aacttaactt tcttccttat actcgattcc cagatcctgt gcaatacctg cgtagccttc
     7441 tttttcaaga cgagtagcca aggcagcatc accagataag acaatacgac catccatcat
     7501 aacatgaact aggtctggga taatgtaatt caacaaacgt tgatagtggg tgataatcat
     7561 agctccaaag tctttcccac gcatctcatt aaccccttta gagactactt ttagggcatc
     7621 aatatcaaga ccagaatcaa tctcatctaa caaagcaaat ttaggctcta acatgagcaa
     7681 ttgaagaatt tcattgcgtt ttttctcccc accagaaaaa ccttcattga ggtaacgctc
     7741 tgccatctct tctttcatac ctaacaaagc cattttctca tcaagtttgg tgataaaatc
     7801 tcgcacggaa atcttatcct catctgcctt accggcattc attgctgcac gcataaattc
     7861 agcgttggta atccctggaa tttctgaagg gtattgcatg gcgagaaaaa gtcccagtct
     7921 cgcacgctca tcaacttcta gatcgagaat attgaccccg tcaagcaaaa tctgcccttg
     7981 ggtcacttcg tagttaggat ttcccataat agctgctgaa agggtagact ttcctgtccc
     8041 atttggcccc ataatggcag ctacttcccc agttttaaga gttaggttaa cccctttcaa
     8101 aatctcttta ccttctattg aaacatgtaa attattaatc tcaagaattg acatgataca
     8161 ccccttattt tctctgtcat ctataccatc tcaagaaaag acagtgtcat ttgcactgct
     8221 ttttttataa tggtcactgc atctattata gcaaaaaaag ccttactcgg cttttttagt
     8281 gtttcaaatc cttcttttct ttccatttca gaagcattgc ttgacgataa tcactattac
     8341 caataaactt taacaagtta aacaaaggcg ttcgcttttc accccagatc tccaatcctt
     8401 caataaaaac ttctaaacca aacaaaagtc caagcatcaa gaggacgcca ccaattcgac
     8461 tagaaacatt taaaagtaaa gaaataaggg aaaaaagcat ggtaatacca taaactacta
     8521 agacagctcc tcgatgagta aagcccattg ataagagtcg atgatgcagg tgcatcttat
     8581 ccggctcgta gaatttttga cctgataaac tacgtcgaat aatagccacg atggtatcca
     8641 taatgggtac accaagaata ataacaggtg tcaccacagc cacagccgtt gaatttttca
     8701 atccttgaag agacaaaacc cctatcataa agccaataaa gagggctcct gtgtcaccca
     8761 aataaatcat agctggatgg taattataag gaaaaaatcc tgcaatagca gaaatcaaga
     8821 ccaaaatggt taacgtcaaa aagaaatcct tttgaggtaa aaagaaataa gatacaatag
     8881 ccatggtcac taaactaata atagagaccc cactaaccaa accatccaaa ccgtcaatca
     8941 agttaatagc attagtgatg gaaacaatcc acaggactgt taagaataag gttaagaaag
     9001 gaccaaaaac taacaacggc cctccaaaag gaattttgaa gctatcaaat ttaaagtcgg
     9061 taaaagccca gacaatcact gcaccaatta gaataccaaa catctttaat ttaggactta
     9121 actcatacaa atcatctaaa aaaccagtaa gggtaattac tgtagcacca atcacgacag
     9181 gtaaaatata actgaagtag gtctgaccaa aaaacatggc gcctttagaa gcaatcggaa
     9241 taagtcccaa acttgctact aaaaaagaca taaaaatagc taatccacca ctggttggca
     9301 tcggaacctt attgacccgt ctggcattgg gattgtctac tgcacccaca cgaaaggcta
     9361 aaaagcgaac aagaggggtt aagaataagg acattaacaa agcccctatc agaacaagga
     9421 cataatctat tgtgaatgaa aacatactat tttatcccaa ctcaatcttt tgtaattgct
     9481 caacagcacc atcaagcatc aattgtaagc catgctcttg taaataagct cttgtttttg
     9541 atccagggtt tgcatgctca atcaatctcg catacatgac attcgcaaaa taagatggtt
     9601 gttgctgaac atctaataaa atagtcatat ggtagcagtt gctcccctta tataactctg
     9661 aagcttctat cgaaaaatca atcgttttag caaaagccac tgcctctgta atcgttgaaa
     9721 aatccaatac ataatggaca tagtctaaag gttctgactc atgattagtt gatggatcag
     9781 ccgcctcaga ctgattagct agagtagctt caacaacatc ttccattatc tcttcaattt
     9841 tttccaattt ttcatgagct ttgacatctc ccttttcacg catggattgc tccaagctct
     9901 tgaaaaaatc ttccggagtc atttgggaca tatcaccaaa ctctgctaaa tcttcaagat
     9961 taatatcttt atttatctca gatttggtaa caaaaacatc tagacggtcc ttgcgtggag
    10021 tcactcgaaa actaagcata ccactatctt taaaattatc tggaagatcg agttcgtcca
    10081 tcacagaata gaaaaactct tctgtttttt cttgaggaat caagaaatct ttcaactcca
    10141 ttcctctttc ttctaaatcg tccatactaa ttgttatttt tagcgttgtc tcgctaattt
    10201 gtttcatttc cattctcaat acctcgcacg cgtagtcatt ttattatact agaaatgctg
    10261 taatttcgca atttatgact aactcctctt ctacaaaagg aaatttaaaa agcgacagtc
    10321 ccaaaggtct gtcgcaacat cctaaacgat atgtaagttt aaaaaacaaa tttaaagaag
    10381 ctataaataa gtaaaaggct tcctaacaca atacggtatt tcccaaaaat ggtgaaatcg
    10441 tgtttcttaa cataatctgt caagaaccta atcgccaata aactaaccac aaaagcggtc
    10501 aagctagcca ctaaaagaat aaggacttgt gcaaaatcaa ggtgatggcc atcaaggaaa
    10561 aatttcacag cctttaatcc actatatcca aacatggtag gaatggccaa aaagaaggtg
    10621 aaatcagcgg ccactgttcg actagttcct aaaataatag ctcctaagat ggtagcccct
    10681 gatcgactag taccaggcac aatacttaag acttgaaaac aaccaatgaa gaaagctgtt
    10741 ttgtaagaca ttctagctaa ttcagtgacg gcaggttctt gttgagcatt ccgtttttca
    10801 atccagataa aggcaatccc gtagacgatt aaagcgatgg caatcggaac cataaaataa
    10861 aaatgtgctt caaaccaatt atcaagagga accgctatta aaatagaagg aatacacgca
    10921 atcaccactt ttagccataa ttgccaggta agctgtactt ctcttgctgt tttcccaggt
    10981 tgaaagggat tgagacgttc aaaataaatc aacataacag cgataatcgc ccctaattga
    11041 ataacgatat taaacatttc tataaaagcc ttatcctgat ttagtcggat aaattcctgc
    11101 accaaaatga ggtgaccagt gcttgaaact ggtaaccatt ctgtgattcc ctcaatgatg
    11161 ccaaagaaaa tggcttttag caattcgata attaacatgt tttctcctta ttaaccactc
    11221 ttattgtgat tttctaaact gtgattaatg ccaagcagct tttttaaaag gcaccgccgc
    11281 cgcctcctcc gccaccgcca gagaagccgc caccaccact aatcccgcct ccggaagaga
    11341 ctgagaaatt tgaggaagtt gtagctgaag acaagctaga caaaaaggtt ggtgtcgtag
    11401 catacattac cattgataat tcacctggtc gaacagcttg gtaaacctca ggtaaggcaa
    11461 tacgatggac tttcaaatag cgttccactt tcttagcgta accaaataag gtggcataaa
    11521 ccaaaacacg gttccaaaca accaaacctt caatagcaac atcctcaaat ttgtcaatgt
    11581 ctcgtatcat gtttttaaag ctctgccatt gatgtaaccg aacacccccc tcaggtgttt
    11641 caatacccaa tttcttgtat tgatctaact tcaggctaat gtaaaagcca aggcacatcg
    11701 ttagcaccat taaagcaagg taaatgaggg ctaacccact ttctttaata gccaagtaaa
    11761 tcaataaacc actatttaga acaagcaaca aacaacctaa tccctggaca ctattgcttt
    11821 ttcgtttctc tgccggggtc atttgacgat aagtatctgg taagtttaac tttttgatag
    11881 tttctaggac attgtttgta atagctgccg acgctttttt catcgcctta atcacctgct
    11941 cagacgattg acggacttct tgctcgagct ttttaccttt gtacgttttc tttaattgtt
    12001 taatggtatc agcatcataa tggtattgac taaacaattg atccaccggc aatgtcacct
    12061 tgtttccaaa agccatatct aagaaggcag cttcctcatc tgtcacacga tctaactgac
    12121 tgatttcaag ataagctttc ccttcttctt tcgttaataa aagcaccttt tggtcgatca
    12181 gatccaacaa ggtagcttga acaagggcct caaaggtcac tcctttaggg atcaataatt
    12241 tctggctttc tgatgctgta ggggataaat aggcaaaact ctgtccataa atcgcttgtg
    12301 tcaacacaag aggcgaaaga tcttcaggga cttcgtaact gtgatctgta tggttggcca
    12361 aatgataacg attgaattgt ttctttaatc ttataaactg tattaactgc cacagaagaa
    12421 aacctacctc taccagagga atgactttgc caaatagcag ctgtaacaag gcccttcgtc
    12481 tggaaatctt agtttccaac gctacaattt tattcttttt actcgttgaa acatcaactg
    12541 gttcttctcc caataatgct tttttatccc aataagcatg caattccaat tgccctgaga
    12601 catttttggc attaatctga tagcgactgt taccttcttt taacacttga ggtttctttt
    12661 ggtaatatcc tctgtgagcc catagattag aatcctgaat atcagttggg gtagtgacgg
    12721 tcaaactcac cttttctaat gttttgtccc aatcactaat cggtgtccaa ttcagctctg
    12781 ccacgtcttg ataagctgtt aaaaggtggt gcagttgcca gataacctta acgtcaacct
    12841 tatcaccagc ttggccagca ttataaagtt ttaaacgata gccatctcca aggtcactaa
    12901 actcttgact aacaggtacc tgttgaccat tctgatatac ctcaacttta ggcttttggt
    12961 caatagcaaa gcccgctggc aaatgacctg cccggcccag cgaaatatac tggccgttat
    13021 aagaagtgtc aaattgatag gttacttttt gctcaaaccg agcagtattt tcttttgata
    13081 acagtaactg accttcatag ttggtgatgc tatagtctac atcagctgct tttattcgta
    13141 tccctaaaag actgaagcag agcacaagcg tcatcaaaat ttttttcatg gcaacatcct
    13201 ctttctgccc tcattttacc atattttaag gagatgacaa aacctaaacc aagtccttca
    13261 tcttattttt aatcattatt ttgaatattt ttccatattt caacctattc actgataata
    13321 tattgaaata ggatgcaaat tgctgtaaaa taggtctgaa tactattttt gaaacaggag
    13381 acctatatga aaaagctaat ccttagctgt ttggtcgcct tggcccttct gtttggagga
    13441 atgagccggg ctcaagcaaa ccaatattta agagtcggaa tggaagcagc ctatgctcct
    13501 tttaactgga ctcaagatga cgcttcaaac ggggctgttc caattgaagg aactagccaa
    13561 tacgccaacg gttacgatgt ccaagtcgct aaaaaagtcg ctaaagctat gaacaaagaa
    13621 cttttagtcg ttaagacctc ttggaccggt ttaattccag cattaacttc tggaaaaatc
    13681 gatatgatcg ctgctggtat gagtcctacc aaagagcgta gaaacgaaat tagcttctca
    13741 aacagctact acactagcca acctgttcta gtcgtaactg ccaatggcaa atatgctgat
    13801 gcaacaagcc tcaaggattt ttctggagct aaagtaactg cccagcaagg cgtttggcat
    13861 gtcaatctct taactcaact aaaaggtgct aagttacaaa caccaatggg agatttctct
    13921 caaatgcgac aagcccttac ttcgggtgtt atcgatgcct atatttctga acgacctgaa
    13981 gccatgactg ctgaagctgc tgatagccgt ttgaaaatga tcactcttaa aaaagggttt
    14041 gctgttgctg aatcatatgc tgctatcgct gtcggaatga aaaaaaatga cgatcgtatg
    14101 gcaactgtca accaagtgct tgaaggattt tctcaaacag atcgtatggc cctgatggat
    14161 gatatggtta tcaaacaacc cgtggaaaag aaagccgaag atgctaaagc atcatttcta
    14221 ggccaaatgt gggctatttt taaaggtaac tggaagcaat tcttacgtgg aactggaatg
    14281 acccttctga tttccatggt cggaaccatt acaggtctct ttattggatt attaatcggt
    14341 attttccgta cagctcctaa agctaagcat aaagtagccg ccttgggaca aaaactcttt
    14401 ggttggttac tcactattta tatcgaaatc ttccgtggga cacctatgat tgttcaatct
    14461 atggttatct actacggaac agcgcaagcc tttggtattt cgatcgaccg taccctagcg
    14521 gctattttta tcgtatctat caatacgggt gcctatatga gtgaaattgt tcgcggtggt
    14581 attttcgctg tcgacaaagg tcaattcgaa gcagcaactg ctcttggctt tactcacgga
    14641 caaaccatgc gtaaaatcgt gctaccacaa gttgttcgca acattttacc agcaacaggt
    14701 aatgagtttg tcatcaatat caaagatact tctgttttga atgttatctc tgttgtggaa
    14761 ctttacttct caggtaatac cgtagccaca caaacctacc aatatttcca aacctttacg
    14821 attatcgcca ttatctactt tgttcttacc ttcacggtga cacgtattct tcgtcatatt
    14881 gaacgccgtt tcgatgccga tacttacacc actggagcaa accaaatgca gattgcggag
    14941 gtctcaaatg tctaactcaa ttattgaaat caaaaacctc aaaaaatctt acggcagcaa
    15001 tgaagtactc aaagatatct ccctttctgt taacaaggga gaagtgattt ccattatcgg
    15061 ttcttctggt tctggaaaat caaccctcct gcgctcgatc aatcttttgg aagagccaag
    15121 tgccggtcaa atcctctttc atggtgaaga tgtccttgct gaacactaca acttgactca
    15181 ctaccgtgaa aaactaggca tggttttcca atcctttaac ttgtttgaaa acctaaatgt
    15241 attggaaaat gctatcgtcg ctcaaaccac cgtcctcaaa agagaccgtg cacaagccga
    15301 acaaatcgct aaagaaaacc tcaatgcggt tggtatgaca gaacaatact ggcaagccaa
    15361 accaaaacaa ttatcagggg ggcaaaaaca acgggttgcc attgccagag ccttatctgt
    15421 caatccagaa gccatgctct ttgatgaacc aacatcagct cttgatcctg aaatggttgg
    15481 tgaggtcctt aaaaccatgc aagacttggc aaaatcaggg ttgaccatga ttattgttac
    15541 tcatgaaatg gaatttgctc gtgatgtttc tgaccgtatc atcttcatgg ataagggatt
    15601 gattgctgaa gaaggaagtc ctcaacaaat tttcgagaat cctacacaag atcgtaccaa
    15661 agaattttta caacgcttct taaaataaga taaaggatcc aactatctct ataccagttg
    15721 ggtctttttt caattcaaaa agaatttgtc ataaaatact ttaccagtta actattttat
    15781 gctatactta tttttgttaa cgttaataat ttatatttag gaggataata tggcagaaaa
    15841 aactgactta tcgtcagctt acagaagact gaaaagtccc aatattaaaa ccagaaaacg
    15901 tgctctgaag attattcacg agtacaaacg ttacggtaaa aaataagatt ttacttttta
    15961 tctctccaaa tttaagtcag acaaaaaaag gctaagacac cccttccatc ttagcctttt
    16021 tgtatacagt ttattaaggg aactatttta aaatatcttt tatgctagag tctagaatag
    16081 ttcaaaacgt taaaatcata catttaaagt agtgtttaaa gtatacgaaa aagaactcag
    16141 cataaaccaa gctctctttc gttataacta attatttagc aatttttgcg aagtactcaa
    16201 gagtacgtac aagttgagca gtgtaagaca tttcgttgtc ataccatgat acaactttaa
    16261 ccaattgtga tccgtcaact tccattactt tagtttgagt tgcgtcaaac aatgaaccgt
    16321 atgatacgcc tacgatatct gaagaaacga ttggatcttc agtgtaaccg aagctatcgt
    16381 ttgaagcagc tttcatagca gcgttgattt cgtcaacaga aacgtttttg tcaagagtta
    16441 caaccaactc agttactgat ccagttggaa caggaacacg ttgtgcagca ccgtcaagtt
    16501 taccgttaag ttctgggata acaagaccga tagctttagc agcaccagtt gagttaggaa
    16561 cgatatttgc agcaccagcg cgtgcacgac gaagatcacc accacggtgt ggtccgtcaa
    16621 ggatcatttg gtcaccagtg taagcgtgga ttgtagtcat aagacctttt tgaataccga
    16681 atgcatcgtg aagagcttta gccataggag ctaaacagtt tgtagtacat gaagcacctg
    16741 agataactgt ttcagtaccg tcaagaatgt cgtggttagt gttgaaaaca actgttttaa
    16801 catcgtttcc accaggagct gtgataacaa cttttttagc accgttagca tgtaagtgtt
    16861 tttcagctgc ttctttttta gcaaagaaac cagttgcttc aagaacgatt tcaaccccat
    16921 cagttgccca gtcgatgttt tctggatcac gttcagcaga cactttgatg aagtttccgt
    16981 ttacttcaaa tccaccttct ttaacttcaa ctgttccatc aaaacgacct tgagttgtat
    17041 cgtatttcaa caagtgtgca agcatatttg gatctgtaag gtcattgata cgagttactt
    17101 caacaccttc gatgttttga atacggcgga atgcaagacg tccgatacga ccgaaaccgt
    17161 taataccaac tttaactacc attagtgatt tcctccttat gaaaatcaaa agaatattat
    17221 ttagagggaa tgctccctac ctattgtgaa aagattaact tacagtcatc tgcaacaacc
    17281 tttcaacaga actattatat aactatttca gaaaaaatgc aaataaatta gccattttca
    17341 taaagggcag cttctttctt ctagccttca aaacccacca aatataggaa agggctttct
    17401 tttttctatg ttctattctg taatttatct ttttattggg aaagatttcc aaaacttcaa
    17461 actgtactat aacgttctgt tacactaaaa aagaggttag gatagttatc ctcaacctct
    17521 tagtggtggt tattcacctt tgtttttctt aatgatttct tcttgaactg acttaggaac
    17581 atcttcatag tggtcaaata ccatcatgaa tgtaccacgt ccttgagtag cagaacgaag
    17641 aactgttgca taaccgaaca tttcagcaag tggaacataa gcacgaacga tttggctgtt
    17701 accatgtgct tccataccgt caacgcgtcc acgacgagct gtcacgtgtc ccataacgtc
    17761 tccaagattg tcttctggag ctgtaatcgt tacaagcatc atcggctcaa ggatagctgg
    17821 ttgtgctgat ttagctgctt ctttaagagc aagagatgct gcgatcttga aggcagtttc
    17881 agatgagtcg acatcgtggt atgaaccatc gtaaagttta gctttaacgt caaccattgg
    17941 gtaaccagca agaacaccgt ttgccataga ttcgatcaac cctttttcaa cagctgggat
    18001 aaattcacga ggaaccacac caccaacgat agcattttcg aattcgaaac ctttaccttc
    18061 ttcatttggt gtaaattcaa tccaaacatc accgaattga cctttaccac cagattggcg
    18121 tttgaagaat ccacgagctt gtgtagaagc acggaatgtt tcacggtaag atacttgagg
    18181 agcaccaacg ttagcttcaa ctttgaactc acgtttcata cggtcaacaa ggacatcaag
    18241 gtgaagttca cccataccag cgataactgt ttcaccagtt tcaacgtttg tttcaacgcg
    18301 gaatgttgga tcttcttcag caagtttttg aagggcaaca cccatcttgt cttggtctgc
    18361 tttagatttt ggctcaacca tcaactggat aactggttct ggaacttcga ttgactcaag
    18421 aataactttt gctttttcat cagtcaatga gtcaccagtt gttgtgtctt tcaaaccaac
    18481 agcggcagcg atgtcaccag cgtaaactgt ttcaatttct tgacggctgt ttgcgtgcat
    18541 ttgaaggata cgtccgatac gctcacgttt accttttgat gtgttcataa cgtaagaacc
    18601 gctattaaga acacctgagt aaacacggaa gaatgtcaaa cgacctacga atgggtcagt
    18661 catgatcttg aaggcaagag ctgcaaatgg ctcttcatca gatgctggac gttcttcttc
    18721 agcatctgta tccgggttaa cacctttgat tgcagggatg tcaagtgggc ttggaaggta
    18781 tgcgataacc gcatcaagca tcaattgaac acctttgttt ttgaaggcag aaccacaaag
    18841 tactgggaag aattcaacgt tgattgttgc tttacggata ccagcaatca attcgtcgtt
    18901 agtgatttct tcaccttcaa ggtatttcat catcaagtct tcatcagttt cagcaactgc
    18961 ttcgattaat ttttcacggt attcttgagc ttgttctaag tattcttctg gaatatcttc
    19021 ttcaagaata tctgtaccaa ggtcgttggt atagatttct gctttcatct tgatcaagtc
    19081 aatgatacca cggaaatcat cttctgcacc gattggcaat tggattgggt gtgcatttgc
    19141 ttgaagacgg tcatgaaggg tttgtactga gtaaaggaag tcagcaccga ttttatccat
    19201 tttgttggcg aaaacgatac gtggaacacc gtattcagtt gcttgacgcc aaactgtttc
    19261 agtttgaggc tcaacacctg attgtgagtc aagaacggtt acagcaccat caagaacacg
    19321 gagagaacgt tgtacttcga tggtgaagtc cacgtgtcct ggtgtgtcga tgatgttaac
    19381 gcggtgacca tcccattgag ctgttgtagc ggcagaagta atagtgatac cacgttcttg
    19441 ctcttgctcc atccagtcca tttgtgatgc gccttcgtgt gtttcaccga ttttatgaat
    19501 tttaccagtg tagtaaagga tacgctctgt tgtagttgtt ttaccagcat cgacgtgagc
    19561 catgataccg atattacgag tttttgcaag tgaaaattcg cgagccatgt gtttctccta
    19621 tttttttagt ttactctttc attatagcac tatttagcaa aaacggatag gcaggaccta
    19681 cccgttatct aaatatttgt tggtaaagat aatacctatt gcctttataa ggcttggtat
    19741 cttattcatt gaactcaggc taaacgctgt gtgaaaaaga taaactttcc tagagacaaa
    19801 ggtttcttcg tcaaatttcc tattttcact ttgcgttcta tacgccttcg tatcttatta
    19861 attgagttcg agctacaaac cactgacaaa aagataatag ttcctagaaa ctgaagtttc
    19921 tgcgtcaatt tctctatttt ggctagcatt tgtttgacgc taaaatatct tatattacca
    19981 acggaagtga gcaaaggcac ggttagcttc agccattttg tgagtgtctt cacgtttctt
    20041 aactgatgca cctgtgttgt ttgcagcatc catgatttct ttagcaagac gatctttcat
    20101 agtgtgttca ccacgagctc gtgatgcgtt taccaaccaa cgaagtccaa gtgttgtacg
    20161 acgttctgga cgaacttcaa ctgggacttg gtagttagaa ccaccgacac ggcgtgcgcg
    20221 tacttcaagt acaggcatga tgttgtccat agctgtttca aatacttcaa gagcgtcatt
    20281 tcctgttgct tctttgatag cgctgaaagc atcgtaaacg atagtagcag ctgtaccacg
    20341 tttaccgtca agcataacac ggttgataag acgtgttacg atttttgagt tatataatgg
    20401 atctggtaat acttcgcgtt taggcgcttg atttttacga ctcattttct cttatccccc
    20461 ttctattatc cttttggacg tttcgcaccg tatttagaac ggccttgttt acggtcagca
    20521 acacctgcag tatcaagtgc gccacgaacg atatggtaac gtacccctgg aaggtctttt
    20581 acacgtccgc cacgaataag aacaacactg tgctcttgca agttgtgtcc gatacctggg
    20641 atgtaagctg taacttcaat aaggttgctc aaacgtacac gagcgaattt acgaagggct
    20701 gagttaggtt ttttaggtgt cattgttcca acacgagtag caacgccacg tttttgtggg
    20761 gcagccattt tagtttgaac ttttttgtga ctgttgtaac caatgttcaa agctggtgaa
    20821 tctgattttt caattttaga tttacgtggt ttacgtacca actggttaat tgtaggcatc
    20881 tacattctcc tgtgtttttt tatttttggt tgatatagca cttggtgaca gcccatatcc
    20941 ggtgcacttt ttgcaacaat tgtcagcacg tctctgtaca cttttgagag accaaaagta
    21001 aaaagtaccg tctaatataa taacacagac ggtacttcat gtcaaataga atttttcctt
    21061 tgatgcaatt gcttatgacg aatgcatcac ctagattcct tacggaacct aaatcctgtg
    21121 aggccgacag ctgccaacat gacgactcct gctttaagag ctctttgagt actttcatca
    21181 acatcagaaa tgagattgct cgttgtagaa gatcctgagc cataagatgt cttagatgag
    21241 ggctgagtaa tcgaagatgt gattttagac acaatggcat tacttgctac catttcagag
    21301 gtttggccaa caagcgcttc tgctacaaga cttgtatttt cagcagctaa tcttgctgaa
    21361 gcttctaata gttgtttcgt ttctttaacc atttcttgaa caagcggagt agtctctacc
    21421 ttactatatg atagcagttt cacgcccgta agagatggag ctacttgcaa atcaggcaca
    21481 gtagctatat cttcgtctaa gtggcgatat tccttttcat tagctaaggt tttaagcaaa
    21541 gtcaactggt gttctgtggt agcaatagta gcttctagac tgctttgttt agcttgtaag
    21601 gctgctaaag tttcttgtgc atttaacaaa gatgaggtag ttttagccaa atcttgctta
    21661 gtattatcaa tgcgctcacg tatcacttga aggcggttag gattcaattt aaagtccctt
    21721 agatattgca aatgagcttt tttagccacc agtgctgtca ctctggctgc ggcttgctct
    21781 gctaaggctt ctgtctggtg cagtgcggct ttcaacgatg ctagcttagc taatgattga
    21841 tcacgagtag cttcgagttg tgcttgtttt gctttagctg ctagtaattc tgttctcaaa
    21901 gaacctttag tatcatttaa ttgtctcact tggaggttta agctgtctga ctgcttaagt
    21961 gtgcttgcta atttaccttg aagttgactt actttagctt gggctgccat aatatcagct
    22021 tcttgatgaa tagccgacaa acgattttct aatgagctta cttttccttt gatcgctgca
    22081 atagtatcag atacagtgcc tactctttgg gcataatctt ttgtacttcc aacggctttt
    22141 ataggggtct tattaaagcg ttgatggtta gcaatgttag actctggaaa cattacaaag
    22201 tgttcattca aagatcccac attgctggtt gaaaatccaa ggtaaacagg cgcattaggg
    22261 ttacgtttat ctacacgtaa aaagttaata gcatggccat atgtatttcc gtgtaaatga
    22321 tctgtaaaga gcatatactt gatactgtca taaataccac gtttaatacc attcacagta
    22381 tgcacatcgt taaaagcacc gatattctcg tacatgttat catcatttcg aatgagccct
    22441 gacgctccgg cagagtcttc aataatagtt ttatcatgag gcccaacacc ataatgccct
    22501 gatacccctg gctgtccgta gacaaatgat ggtcttgtat taccatgagt tttcttatag
    22561 ctggtactaa gtaatcttgc aaattcttgt gatcctgctg taacagtaac tggtggtaga
    22621 cctaattgtc ttcttacact attaatcatg tgagctgcaa actgcgctag ctcattttgc
    22681 acttctggtg tcaaattatc gggatcaaca aagcgattac gatctgctgg aatatcttgg
    22741 tattgattta attgattacc tggactagct ttggcaataa tttgatctgc atgctctttg
    22801 taataattat tgtaactagc tgatccaata taaccactag cttctaattt tttaagttct
    22861 tcaagaggat agccttgcgg tgctttcatg gtattattac ccacaatgct atcttgagta
    22921 gacggagctg aggatttaag acgactaagt tctgcctctt tttctgctag agcagctttc
    22981 tgagctgcca actcttcagt caattgcttt ttaactttag ctttttgatt ttctaagtca
    23041 gctttagcct tctccaattc tgagcttaat gcttttgtat tatcattagc cgtttgagct
    23101 gctttagtga tagcatcagg attgctaatc atagcattga gcttagcaat attttgttca
    23161 gacgttttga cttgttccac taaatcttga gctcgagtag tttctgctga aatgctagct
    23221 ttttgttctg acaatgcagt ctcttttgaa tgttgatctg cttgagcatt atgaagctct
    23281 gtttcagtag ctgttaactc tctttgatgt tcggctcctt gggctaatag cgtctcctca
    23341 ctacttgcaa gagtattagt gtaaatttct tgtgcagagg ttaaagcttt ttgttcatta
    23401 tcttgctgct cttttaagtg gttgatttca gcagtagttt ttgtcagagc ggtagcaagc
    23461 tctgtcagtt ctgctttttg ttgactgaga gttttttcaa ctgcatcaat agttgccttt
    23521 gcctcttgag ttgtttctgg ttttggtaaa ctatcgtcgt gagtactact cgccttcgtt
    23581 tctcctgagg ctctatcatc tgctttgact tggtgagata cgcctacact ggcactcaat
    23641 aaagcaattg ttgaggttaa agcaatcttc tgcttaactt ggtttggctt cgtttgttct
    23701 aagtccattc tctctccttt ttccatttat cgaaaatatt accaacttct acaacaacat
    23761 tgttgttttt gacatcaatc tctgaaactt tcagcaatga tttgaaggtc atttgctcac
    23821 gctctgattg agcgttttct gcaaacacag caacaccaac taaagtgctg tcaaattctg
    23881 tcaagagact gatcattcct gtaatcgtcc ccccgccctt caagaaatca tctacaatca
    23941 atacacgact attgggtttc aaactacgct ttgacagaaa catcttttca atacgatcac
    24001 tagaagcact cgcataattg acagacactg tcgatccttc tgttattttt aaatcacgtc
    24061 taacaatgac aaaaggaaca cttaaaatat tagccactgc atttgctaaa ggaactcctt
    24121 tggttgcaac tgtcatcaca gcgtcaatct tttctccttt aaaggcattg gcaataatac
    24181 gaccaatatt ttgtaaaatt ttaggtgtac tcagcaagtc tgacaaatag atatagcctc
    24241 caggtaagat gcgatcactc tctgataacc tttgacacag gtcttcaaca atggtacgcg
    24301 cttctgtttc tgaaatactg ggggtaaaaa ttacgcctcc acttgctcct gtaagtgtat
    24361 cgatatcacc aatgttagct tcttcaaaag ctttcttgat aatagcgata tcttctgaga
    24421 tagaagattt tgcggcctca tatttagttg caaaggtgtt taaactagtt aatttatacg
    24481 gattgttaat caaataattt gaaatgacaa ccatacgttc acttcgtctt aatttcatag
    24541 tttccccatt tttatgtact ttttgctatt ataccataaa gttaataaaa aacgaacatt
    24601 cgattaggaa aatattggtt tttttgttct tattaatatc atgcaagaat tcaatctaag
    24661 ataaactaat caacattcct actgaaagga cattctactt aataaccata acaagagcca
    24721 aaaacactta tgaaaccatc ataagtgtta agcacatcaa aaatcatcac aaaagcaaag
    24781 gaactattac ttgagaaaca ctgatcaata gtttggcttg taaaaagacc gattatccat
    24841 ggcaaaaatc cgattggtca tctcgccctc gctaacacgg ctaagagctg ttgtcatcat
    24901 catcatatta gcatcaatat tgtcaatcat atgaataatt tcagcttcca tgatgcgtgg
    24961 acgtaccgga ctaccgtatt ctaattgccc gtgatggctt aaaatcacgt gcctaaggac
    25021 aatgacttct tctttggtat catcgatttg tagttctgaa attacttttg taatttcttc
    25081 gttaatgagg gaaatatgcc caatcaagtt accacgaacg gtgtattctg tattatctgg
    25141 tcctgttaat tctatgactt tagctaagtc atgtaacata atacctgcaa acagtagact
    25201 cttatttaag tcagggtaga tatctccaat gctatctgct agtctgacca tcgtagcagt
    25261 atggtaggcg aggcctgact caaaagcatg gtggtttgtt ttagctgcag gataagtata
    25321 aaattcttta tcatacttac gataaagagc ccttacaatt cgttgccacg ttgcattttc
    25381 aattttaaag agcatctgtt ctaaatagtc acgtacttct tcaacactga caggtgcctt
    25441 ttctttgaag tcctttggat cattgggctc ccctgggcga acatttcgta aggtgatttg
    25501 attaacctga ggggtaccat tatagacctc gcgtcgccct ttcataaaca cgactttacc
    25561 agcggtaaat tcttccacat tataaggttg ggcatcccac agatttcctg aaatctcgcc
    25621 agtgtcatcc tgaaaggtaa ggctaataaa atctttacca gcccttgtct tacgaacctc
    25681 tgccgactta atgagataga acccttcaaa aagctggtct tttttcattt gattaatttt
    25741 cattattttc ctcttctaat aagggcatgt tcaagagaga ttttgttgct tggtcttgat
    25801 aagtttcaac ggtattcaag gctcgaacaa tggcatttgt ccttgttgaa atgagctgat
    25861 ccagcgtatt attagctgta ttcatttgct tttgagcctt ggcaagcagg ccgccaaatt
    25921 tatcgaattc taacttgaca ttgcccaaaa ttttactgat gtcatcagca tttttttgga
    25981 tattaagggt cttgaaacca acagataagg aattgagcaa agcagacagg gtcgaaggac
    26041 ctgcaaccac aatattttct tcccgacgaa ggctatcaaa gaaagccgca tttctgacca
    26101 cttctgaata aagaccttct gttggtaaga acataactcc gaaattggtc gtctctgggg
    26161 gattcaagta ctttttatga atgtctttgg caaagcgttt gatagctgct agaagtgctt
    26221 ttcggctagc ctcgatggcc agtttatcac caacttcgta agcatcttct aatcggtaat
    26281 aatcttcaag agggaatttt gagtcaatcg gtaggtaaat atagccgcct tgaccatttc
    26341 ctgggagctt aatcgcatat tctacgcgtt cactagaacc actaaccgtt acaaattctc
    26401 tttcgtactg gcttgatgtc atgatatcct caatgatttg gcctagttga agttcgccta
    26461 aaatgcctcg tgttttggta ttggacaaaa ccttatttaa agtacccaca tcttgagcca
    26521 cgctacgcat ttctcccaag cctttattga cactttctag ttgcttggat acagaatcga
    26581 aagaggcgtg cagacgattt tttaaggttt cttccaattt ttcttcaacg atctggcgca
    26641 tttcctccaa acgtttttcg ttagattctt gcatattttt gagcgattgg ttgacctgct
    26701 ggttaatttt ttctaagcgt ttgtcagacc ggtccctact atcagacaaa ctacggtgca
    26761 agacgtcacg aatatctgtt aattgttggt aaaggtctgc ttgttgtcgg ttcatcagct
    26821 gtgttagctc taacaattgt tgcttgttag ctgtatccaa ctggtaggtc atttgatcag
    26881 acaaattatc cgcgttgcct tctagggttt gggcaagctg atgttgaagg ccattaactt
    26941 tgaacaacag ataagcccct aaacctaaga gaaccaagac caaaaggaac aagataaggt
    27001 ccatactaac tccaatcttt actttgaata ataatcaagt agccacttgg caaactaact
    27061 gtaataggtt gatggataaa ggcattactg gaatagattt tctttttgaa aaaattatct
    27121 tgcgtcaact caaatttagc accagtaatg gtcaagtcag ctgctccttc tgccataaat
    27181 gccacatagg tcattccttc ttcttgatgg ataaggtgct gacctgccgg gcggtaggta
    27241 atcatatttt gttggtcacg caaggcgatt tgtgccataa agggagcaat accagggtcg
    27301 ctaggcaaaa aaatattgga taagaggtgg tccattcgac ccccaaaagc cccaaaaatg
    27361 gtcacttccg cctcaggaaa acgagcaaag acctctttaa gggctaattc cgtatccgta
    27421 tcattttttt ctggatgagc agtaataaaa agctctgcct tctcttttat atccgtaaat
    27481 gctttttggg aaaccgaatc aaaatcacca acagccatat tcaaaggaag cccattttct
    27541 aataaaaata ggctccctct atcaataccg acaaaataat caaaatcacg gctgatataa
    27601 gagagatctc ctcccgcaaa aagagcaact ttagacattc aaggccgtcc ttaaggtttg
    27661 gacttggctc actaggtcac tggccttgaa aaggtaagaa cctgccacaa agacattggc
    27721 ccctgcttca taacaagcac gaatggtctt attgtctact ccgccatcaa cctcaatgtc
    27781 aaaggacaat cctttttcat ctcgccattt ggctacggta gccacttttt ctaaacattc
    27841 tgggataaag gcctgacccc caaaacctgg gttgactgtc ataatgagga cttggtcaac
    27901 taagtctagc aaaggttcta gggctgttgc aggagttcct ggattaatca ctacccctgc
    27961 tttcatgcca gctgccttga ttttttgaag ggctccatga atatgacgag tactttctgt
    28021 gtgaatggtc atgatatcag caccagcttg agcaaaagcc tcaacatagc gttcaggatc
    28081 aaccaccatt aaatgacaat caaaaaccaa tttactgtgc tttctcatac ttgccacaac
    28141 atctgcacca aaactgatgt taggaacaaa ttgaccatcc ataatgtcaa tgtgaacata
    28201 ttcggcatct gtttcttcaa tacgagctag ctcagaagca aaattagcgt aatcagctgc
    28261 tagaatagat ggggcaattt ttagagttga catggagtag acctactttc ttttgataac
    28321 ttttttatat gtttcacgac ggttttcaat ttcactaaga aattgcaggt aatgctcata
    28381 acgaactggc cacaactctc ccatttcaag cgctgccttg acagcacact tgggttcgtg
    28441 ggtatgggta caggatctaa acttacactc atggctcagc cggcgcagct ctggaaaagc
    28501 ctcgttcaaa tcttcagcat tagcaatatc atagtctaat gatgagaaac ctggcgtatc
    28561 cgcgattttt ccgccatggg tattgtaaaa actcacagct cgggtggtgt ggcgaccacg
    28621 ccctagacta tctgagattt ctcctgtttc aagagccaat tcgggagcga ttcggttgag
    28681 aagggttgat ttcccaacac ctgtttgtcc cataaagacg gtaattttat cagctagcaa
    28741 aggcaacaat tcctcaagac tggtcacaaa atcgtaaccg attgcctgat actgtcgacc
    28801 aatagcctta atctcctcgg gactatctaa taagtccatc ttagagatat aaaccactgg
    28861 atgaatggct ttgtgttcaa gcaagatgag aaagcggtct agaagattgc tgttaaattc
    28921 tggttcttta gcagacataa taaccaccgc ttggtcaata ttgacgatag gaggtcttac
    28981 caaactgttt ttacgaggat gaatcgctaa aatataacct tcagagttgt cctctgctga
    29041 gaaatccacg atatctccaa cataaggtgt ctcaccgcgc ttcctaaaat taccacgcgc
    29101 tcgcgtctga tatacctgtc cttctgactc cacgtaataa aaaccagcca gagatttaat
    29161 gattttacct tgcaactgtg ctcctttgcc ctactataat aactctatta tatcagaaaa
    29221 ccgctcccaa atcagcattt gactctaagt ttcgcttgtc ttaaaaactg tcaagattct
    29281 ctagaccact ggctatcatt taggtcactg ctttttaaaa atagaatatt ttatcaacta
    29341 aaaatcagat cattgatgat ttttgaggta ggaaacgata tgaattttaa gaagaccttt
    29401 gctatttacg aaaaagagtc taaccgtacc gctatagtca cgctcttgtt aattgcccct
    29461 tttttccggg gtattaaaaa aactagctct gcactgcgat accttaacgg ccagcttcaa
    29521 taagaaaaat tcccctgaac tgaacatttc tgttttgtct acaagggaat tttttattgt
    29581 caccggggga aagcttttat aatccaactt cttttaaagc atcagctaat ttgccaaaat
    29641 cttgaatcga caaggcctca ccacgaatag aaggcttgat atctgctagt gccagacctt
    29701 tttcaagttt agtcttgatg tcttcagact tcccaaaatg gctagtcaag ttattccaca
    29761 gggtcttgcg acgatggaca aaactgagac gagatactct gaaaaagaaa tcttcgtcct
    29821 taacctcaat caaaggctgg tcgcgacgca ccattttgag gatagcacta tcgacatttg
    29881 gtgcaggtac aaagacggtg cgcggcacaa tgaaggcaac cttggcagtc atgtaatact
    29941 gtaccgcaat ggacaaggaa ccataagctt tagtgtttgg ctccgcagaa atacgatctg
    30001 ccacttcacg ctgcatcatg actacaaact cttggaatgg aattttgctc tcaatcaagt
    30061 gcatgagaat aggcgttgtg atgtagtaag gtaggttagc caccaccttg ataggcaaat
    30121 caggattttt aaactgcttg atttgggtct gcaaatcagc tttcaaaata tcttgattga
    30181 ccacttgcac attatcaaaa tcgcgcaagg tatctgccaa aatcggcacc aagcggtcat
    30241 caatctcaaa agccatcact tcagcagcat tttctgccaa aaattccgtc aaagccccaa
    30301 ttccaggacc aatctcgata acattgacat tctgatcaat ctcagccgtg tcaacgattt
    30361 tctgtaaaat attggtatcg gtcaaaaagt tctgaccaaa agatttcttc aaggtaaatc
    30421 cgtgacgatc aaggacagcc ttggtcacgc tataatctgc aattctcata tattctcttc
    30481 tttttatgat cactttcttt ttggcatttg aaccactagc ctaaactttt ttgccaagac
    30541 acgccattca gttaatgggg ctgttatatt ttattgtact ctttactcct catatgtctc
    30601 catcacttct tccacttctg ctagggtaat gccaaataat tcgaggcgct tgagcagttg
    30661 tttgccattg gcatagccga tgcggagctt ttcgcccaag tattccctgc gtttacggct
    30721 atctgacgcc attaaaagcc ctagacgaat caggtctgtt tgacgaatgt caaaataaga
    30781 ctcatcatca tattgctgag tgacatgagc aagtgccttt tggaggtcct caaaattggc
    30841 atgttcaacc cctaaggaac ggcccttact cttagaactt ggagtagcct catttcggtt
    30901 taaaaaggcg tgacgagctg ttggcacagc tgccataatg agcttacgaa tgcgctcacc
    30961 attataatct gggtctgtca aaacaatgac accacgcaag tcatttaggc ggttaatccg
    31021 ttctaaatct tcttcagtga tagcagagcc tctggtctca taggtatcca cctcgtaaaa
    31081 acggcgtagg ttagccgtgt cgtccttgcc ttctacaaca agaacctctt gaatattaat
    31141 tttttcagtc aagcttgaat accctctttg cattagcagt cgtttctttt gcaacttctt
    31201 ccacggtcat tccccgtagc tctgcgattt tatcaaccac ataacgggta taagctgtat
    31261 gattttgttt gccacgtttt ggaactggtg taagataagg ggcatctgtt tccaccaaaa
    31321 tcttatccaa aggcaagtgc tgcgctgcct cttgaatatc aagggccttt ttgaaagtga
    31381 ccacacctga aaaagaaatc atcatgccaa gttcaatgaa acgttcagcc atctctaatg
    31441 atcctgagta agaatgcatg atgcctccac gagggccaac accagctgct ttgatgacct
    31501 cataggtatc ttccaaggca tcgcgggtgt gcaccacaaa aggcaaatca tggtcttttg
    31561 ctaattgcat ttggcgctta aaaacctcta tttgcacctc tttggggtcc tccatccaat
    31621 aatagtctaa gccaatttca cctaaggcaa tgactttggg atgtgataat tgagagacga
    31681 tagactcctc aactgcttca gaataagatc ctgcttctgt cgggtgccat ccaatagtag
    31741 catacacgtt aggatactgg tctgcgagag caagtgctcc actaatagtg gtctggtcaa
    31801 agccaaccac attatggtag gccacgccca tttcttgagc caaagtcaat tcttcagttt
    31861 cgtgtccttg aaattctgct acattcaggt gcgtatgggt atcaaaaata gttagttttt
    31921 ctactttatt tgtcatgatg ttattataac ataaagatct taaccacatc agaaaacttg
    31981 gtgagaactt ctgccgttta ggttgatcgt aaaacccttt gctagctgac acttgtctat
    32041 tttctacttt tttgacaaat gacctttaat agtcggctcc tacataagcc ctcaaaaata
    32101 ctacaaccta ctcaaataaa gtgggttgaa caaatctgta tcacaaaaag ggtcgctacc
    32161 ttctgttagc gatctatgct atactagtag gtagttaaac tgtaaggagt gtgctttgct
    32221 atgcctaaaa accaccgcct aattaccaaa atcgaagcat cattggaaca tatgaccagt
    32281 ttagaaaaag ggattgctca tttttttatt acaaccgatc tgacacctca agagttgacc
    32341 gcatccgaga tagttaagcg actacacatc tctcaagccg ccttgactcg atttgcaaaa
    32401 aagtgtggtt ttactggtta tcgtgctttt gcctttgatt accttcacag tcttcaagaa
    32461 tcacaagaga ctttccaatc tattcactta gaattgacaa agcgcgtgct gatggactac
    32521 gatgctctta ttaataaaac ctatgagctc gttaatgagg aaaaattact gaacttagcc
    32581 aagctgatcg attcttctga gcgagtctat ttctttggca aaggatcttc tggactagta
    32641 gcaagagaaa tgaagctacg ctttatgcga cttggtttaa tctgtgatgc ttattcagac
    32701 actgatggtt ttacttgggc aaatagcctc gtcaatgaaa attgccttgt ttttggtttt
    32761 tctttatctg gcaaaacaaa ctctgtcatc acagcacttc atcaagctag tcagcgaggg
    32821 gccaaaactg tcctcttaac aacagataat caaaccgaat ttgacgactc cttagatatt
    32881 attcccgtat catcaaccca ccaactacat tatgggaatc gtgtgtcacc acaatttcct
    32941 cttcttatta tgatggacat tatttatgct tacgttttag cgattgacaa accgcacaaa
    33001 gaaaaaatct tcaaaaacac tattattgac aaagaaaata acgaccttta gactacaata
    33061 gcaaaaaggg cgttgttttc tttttaaagg gtcgtcattc acctccccca gtatacttaa
    33121 acaagaactc ttcacgtcat atagactcac agccactaag attagctact cgctaaatta
    33181 ttttcgattt tctcaggagt tataaatgaa caggatcgct cattcttttg tttaaaatgg
    33241 tagtaagctc ctaatatacc agcattattt ccatgactag caaacttcag ctgagttttc
    33301 ttggcaagac tagaaaccaa gtagctatca agagctgtct ttaatttatc agctaaataa
    33361 tctttttgcg ccatgatacc gccaccaagt accaccacat ttgggttaac aacgtagcag
    33421 atattagcaa taccttgtcc taagtaatcc acctgcttac taatggctgc tatacaaatc
    33481 gcatcacccg ctttagcctg ctcaaaaata cgacgaccat cccattggct aatgtcatcc
    33541 ccataagcta aggccacctc ttgaacaaga gctgtggtag atgccagatc ctgaaactga
    33601 ccatctgaca aatgaaggta accaacttcg caagctgaat gactactacc atgaaaaact
    33661 tgggaattaa acaataaaca gccaccgatt cccgtcccaa ttgtcaagca aagagccaca
    33721 ggataatcct tggcactgcc agaaatagct tcggctagac cagcacagtt aacatcgttt
    33781 tccacttcac acggtaaccc gaaagtctct tcaatctcgt ttttaaactg agttccagca
    33841 tagttaggaa tctgagggcc ggcataaaag atttctccct tatcaggatt aaccattcct
    33901 gcagaagaaa tggccactcc agccagatcc atttggtctt gataggtctt taccaagccc
    33961 ttgacctttt ccaaaataga gggaccacct ttataagcct cagtggccat ttcctctttt
    34021 tccaacaggt ctcctgtttc agaaatcaag ccatacttga tagcagtacc accaatatca
    34081 attgctaaat aatgcttcat ttgttatccc ctcgcatctt attaaaaggt ttccttagcc
    34141 tgattaatca gagcagcagc ccgttggcaa ataaccctat cttcctcgac caactcagct
    34201 aaaggtgatc gaacagaacc aatatcaaga ccctcattaa tacgaagtac ttccttaata
    34261 accccataca tattgccgtg agcagaaaca aggacaccga taatctcatt aatagtatat
    34321 tgaaaggtct tggccttttc taaatccttg tcaactataa gttgattcag ccttaaaaat
    34381 aattctggca tagccccgta ggtaccacca ataccagcag cagcccccat caagcgccct
    34441 cctagaaatt gttcatctgg gccattaaaa acaatatgat cgtccccgcc aatcgcacag
    34501 aaggtttgaa tatcctgcac tggcatggat gagtttttaa ccccaatcac gcgcttatta
    34561 gccaacatag tcttataaag gcttggggtc aaggcaaccc ctgccagttg aggaatatta
    34621 tagatgataa aatctgtgtg aggagcagcc gaagaaatcg cattccaata atcagcaacc
    34681 gcatattctg gtaaccggaa ataaataggc ggaatagctg caatggcatc cacgcccaaa
    34741 cgttctgaat gagctgccaa ttcaatacta tctttagtgt tgttgcaggc aacgtgatta
    34801 ataatcgtca gcttgccctt agcgactgcc atgacatttt ctaacaccaa ttgacggtca
    34861 aaaacgctct ggtaaataca ctctccagaa gagccattaa tgtaaagccc ctgaacccct
    34921 ttgtcaatat agtactgggt caaggcacgc acacgctcag ggctaatagc tccttggtca
    34981 tcgtaacaag cataaaaggc aggaataatg ccttggtatt tcgtaagatc tgtcatagta
    35041 atgtccttta ttcaatgtca ttattaagtg ggaatcgcct aagaagagat tccatgataa
    35101 tcaagtagag gtaagttagg ctactgatgc cgatgatagc tagcaaagac acgcctccaa
    35161 ataacgttaa cagagacaat tgtaggctaa atatcgtgag acaaataaga gccaagaaag
    35221 caaaactcca tggaaaaaag agtccggcta gtaaaaagct tcgcttaaac agcgtagata
    35281 gggaaaggtc tcttttgacg gcctgaggat aagcgtacaa aaagagtata actgccaaaa
    35341 ataaaacagc aatgcaaagt accttaaacc cttgaaaaac taggcctgat tggtttcgaa
    35401 ttaagaaaag atctaagaca caaatactca ttatcaaaag ctcaataaga cctaggcgca
    35461 gcccactttt aaaataatgt ttaaaataag aactataagt attaaaaagc tgactaactt
    35521 gaccttctcg ccaatccaac aaactcgcat acaaagccat tttagcaacc ccaatcgtta
    35581 gaaggggaag gcaggacaag acagataaga gattaaacac gagcaaatca aacagtgctg
    35641 cgctagccct catccattta ctatcaagct tgaagagaga gtgtaaaagt ccctgttttt
    35701 tcgatgtcaa atcacaactt cctttctaga aatacgctta caaacaaaag ctaactctcc
    35761 tcttaaacgc ttaacacatg acttgcttcc cttttgactt atctatctat gcacctaaat
    35821 taagaggcaa cctatagatt aagcttagtg acacgcttta tttagtctaa cctttcacag
    35881 cacccatagt aatgccttgg gtaaatgatt tttggaagac aagaaatacc gtcacaatag
    35941 gcactgcagc catggcagcc cctgccataa tcaagccata attagtagcc atttcagctt
    36001 gcatagtagc aacaccaagt gaaatcgtta aattttcccg agaggttaac atcaccaact
    36061 gcataaaata atcattccaa gtattgataa aggtaaaaat tgctagcgct gcaaagcctg
    36121 gtttgacaat agggaaagcc acattgaaaa aggtacgaat ttcgccacat ccatcaatct
    36181 tggcggattc caataactcg gttggaatat tttctgagaa ctgtttcata aggaaaacac
    36241 caaatggcca gcccacaaga ggcaaaataa cagccgccaa agtgtcatgg attcccataa
    36301 aattaacaat ccgcacaaga ggcactagaa caacctgttt tggcaaggcc atagcagcaa
    36361 taaaaatcga aaacaaaagc cgctgtccat aaaaccgctt tttggccaaa gcatagccag
    36421 ccaacgagga ggttccacaa accaagaaca tggtcgccac cgaaataaag acactattcc
    36481 acaaccattt taaggctgga ttttgcacta ccaaggcctt aaaattttca atagtaggcg
    36541 cctttggcca ccattgcggt ggaatcataa tggtatcggc ttgagcctta aatgctcctg
    36601 tcataatcca ataaaatgga aaaataaaca aaatggtcaa aacacatagc atcacagtgg
    36661 ttaagatatc tgatgcggtt agtttctttt tcgtcatctt aatatcctcc taatattcca
    36721 catcattacc taaaatttta aattgagcaa agctgatgat tgcaatcatg actgccaaga
    36781 atacacccat tgtgttggca tagccgtatt cagagagctt aaaggccttt tcatacaaat
    36841 agtacatgag ggtactggtt gaataatttg gccctccaaa cgtcaaaagt tgaatcaaag
    36901 caaaacattg gaaggaatta atggttgtta taacagcaat atataaggtt gttggcagca
    36961 gacttggcca cttgatattc caaaacacct gaaattctgt ggcgccgtct acacgcgcag
    37021 cttccatcaa agaattatca atatttccca tagcagcaat atatagaata ataggctgtc
    37081 caacagatgt ggttaataaa ataacaataa tagctaacaa agcccagtgc ttatctccca
    37141 gccaactaat gttttgttca atcacatgag catattttaa gacataattc aaaatccctg
    37201 acatcggatc atagatccat ttccaaacca ccgtcaccgc aacacttcca gtaacaacag
    37261 gtagaaagaa aactgcccga taaaacgaac gtgccaccac atttttgtcg taggttttag
    37321 ccgccacaaa gagggaaaag aaaactacaa caggtaccga accaataaca ataatcaagg
    37381 tgttaataag ggacttcatg aaaatgggat cttgaagcat cctagcataa ttagcaaaac
    37441 caacaaaggt aaaatccgtc atggaataat tgaaaaaact cgtcacaaag cccataatca
    37501 tcggtatcaa gacaaaaatc acaaagaaaa ccaagaccgg agctaagaaa gcgtatgaga
    37561 tgagcgtctc tctcattttt aatttattga cgttcacttg taatacctct ttttctatta
    37621 atctctccta aaaaaaggaa aggctccttt ccagtgacca tttgacatgt gccgtgaaaa
    37681 gaagccactt gttctgaaca cttattgtgt ttttttgatt gtcttgttcg ctttttcagt
    37741 gaaggctttc aaagcatctt ctggcttttc atcaccatta gagacggctt gaaccattgg
    37801 gaaccaaaga gttctcattt cagcaaaccc atcaatcgtg ttgtagtatg gtgagtagaa
    37861 ttttgtccat tcagcaattt tttccattcg tttgtctttg taaagatccc cataagaagt
    37921 tcttacaggg aaagcacctg tacgaacaac atttttaggt ccccattctt tatcatcagc
    37981 gataaattgg ataaatgtct tagaggcagc gactttttgt tcatctttgt tattaaagac
    38041 cgcaaaacca tttacgaggt attctagttc tggtttgcca tcatctgatg ggaatgggat
    38101 ttcaaggtaa tccactttac tagcttctaa caatttagct tggatgcctg gttgtgcagg
    38161 cgcccaaaga atggtaaagg aagtttggcc attcgcaaag ttttgaatat cagctgaacc
    38221 gtcgtattga gaaccattca tcattaaacc atctttaatc caattggaaa tcttggtcat
    38281 ggctttaata gagttagcat catctgtggt gtatttggtt actttgtcat cggtaatatg
    38341 actactataa aggttagcaa agaaggcacg tggtccttgg tcaccacctt gaccattagc
    38401 aaagaaagaa cctgggttat atcctttgtc cttcaatgct ttcaagactt tttcaaaatc
    38461 atctgttgtc caaccctctt tcacaaggtc aaggacgcca gcatctttga gcattttttt
    38521 attcaacgcc atgtagaatg gagcagagct gataggatac atgtaagctg tatctcctgc
    38581 ttttgaggct tgaatcaatt tgtcattgtt aacatctttg gtaaactctt ctgtgaacaa
    38641 gtcattcaag tcagccaatt tcccattttt accatattga atgatacgac ctggagcatc
    38701 aaagaggaca tcaggagctg ttccagcttc aatagcagtt gtgattttct caggaccaga
    38761 tgtaaaatca atggtttcca attttacctt gatttctgga ttagctttct caaaggcagc
    38821 aatcaatttc ttctcatagg ttcccacacc atcttcagct ttttcttgcg tgaagaccgg
    38881 gaaagcccac catgtgattt ctgtcttagc agtatcagat ttacttgcac cagcctcttt
    38941 ctggctcttt ccgccacaag ctgctagtcc taaaacagat gcaccaagca tcgctaatga
    39001 agctaacttc ttcatgttca tcgtaaaatc tccttttttt gatgtgtgtt tctagtttga
    39061 caaccactat taggatttga gcgcttcgat aaaacgctct gcaatttcct taggccttgt
    39121 gatggcccct ccaacaacaa tacctgccac acctaagtca ttaattttct tggcttcttc
    39181 tggggaatga atctttcctt cggcaatgac agcaatgcct gctttgcaaa gaacttctat
    39241 caatgacaca tcaggacctg cttcctgacg gctatacggg gtgtagcctg acaaggtggt
    39301 tccaacaaaa tcaatgccag cctgatgggc cactagtcct tcatcaaagg tactaatatc
    39361 tgccatcaaa agctgattgg ggtacttttc cttaacttgt cgaataaagc tagcaatatc
    39421 caagccatca tgtcggtcac gcttggtaca atccatagca atcactgcaa tatttaaggc
    39481 agctaattga tccacttcgg tcatcgttgc cgtaataaaa ggctcttgcg gcgggtaatc
    39541 ttttttgatg ataccgataa ttggtaggtc tgttatggct tgaatttctt taatatccct
    39601 aaccgaatta gctctgatgc cgacagcacc agcttcttga gcagcttttg ccatcagtgg
    39661 cataataccc ccagtctctg aatagagagg ctcacctggc aaagcctgac aagaaacgat
    39721 aatcccaccc tttaactgct ccatgagctt ttctttggtt ggtttatcag gcatagtttc
    39781 tactccttgt gtttcttagt tttaataaaa ataacgttca caaagttatt ataacaaaaa
    39841 ataaagcgct ttcaatagcg atgagacttt tagaatctac tttcattttt tatattattt
    39901 tctattattt ggaatgctct ttcatacaac aaataagaag gtaaggagtt gacaccatac
    39961 ttatacattg caaatttccg attagaaaac gttaaaaaac caagagcctc gagcactctt
    40021 ggtttacttt agttgtattt tttgcaatta agctgataat actttacgtc ctttacgacg
    40081 acgtgcagca agcacgcgac gtccgttttt agttgacata cggtgacgga atccgtgttt
    40141 acgttgacga cggattttac ttggttgata agtacgtttc acagtgaata cctcctcata
    40201 gattttgtat tcgtttagcc ggctatttgt gatatcagtt actaaacata ctataatatt
    40261 ctatcttaaa gagggtctac tgtcaagatt tattttcgtt tttcaacagt ttctctctca
    40321 tttaagaggc cgctcatttc ataaagtgtg tcttctttga cactgttcct ttgccttacc
    40381 gttgaaacct tatcaatagc aacaatgatc aatgagatta gtaaaacaaa cggttaagct
    40441 ggtcatacaa aaaatcttcg atagctaaac taactaccaa agattctttt taggatctaa
    40501 cgttgaagac tgactaccac atatcggtta gggtcattgc cttcagaata actatcaacc
    40561 ccttcaatgg atgaaacggt tttatgaacg attttacgct cactgttact catgggatcc
    40621 atggtgtaat cttgaccaga ttccaagacg cgtttggcaa ctttttgcgt aaagtcaatc
    40681 aaggtttctg ttcgatgttc cacataatca tggacattca aggatactga aaaatttttt
    40741 gaatagcggt cgtgcaagaa attttgcgcc aacaactgca atgatttcaa gaccttacca
    40801 tggtaaccaa tcacacgtcc cgcctctggc gtttcaatct gcaaattgat ttggcgacga
    40861 ttgttgctgg tttcaacggt agcttcaatg tccatttcat agatgatttt agtcacataa
    40921 tcggacactt cctgagcagc tttttcaata tctttgctga aaccatcatt atcagcatct
    40981 tggggcactt ctgattcctc gactgggatt gacggttgtt gtgcttttct ttcagtgact
    41041 gtctcagcaa gattagaagg ggtttgcgct ggactatctt cagacatgag aggaaccact
    41101 ttggtatctt ctgcttctaa cttttgagtg gcttttattt cttcaggttc tacatcagca
    41161 gaattgaccg cgggagcatt tttttgatta atatcctctg gaacacctcg agtggctttt
    41221 ttatcagcct tataaaccgt cttgtcgctg ataccttcga tatcaacttg ggctggcttt
    41281 ttaccgaacc cgaggaaacc ttttttctct tttgaaatga ctttgatatg cgctttaagg
    41341 cgtgataacc ctaactcttg aagtcctgtt tcgatagctt cttcgactgt ttttcctgta
    41401 aataatacca taacctaaac tcctattttc tcttcattgc ttttttacga gcacgacgtt
    41461 cacgaagacg gcgttctttt tcttcattgg caagacgctg tctttcggca ataatcttaa
    41521 aaggattgtt taataacagt agttgtacca cttgaaaggc gtttgagacc gtccaataga
    41581 gcactactcc actagccaag ttaaagccca tgaaaaagat cattagcggc atcacataaa
    41641 tcataacagt catcatgaca tttttttctt tagccgctag attggtcaac caagtggaca
    41701 agaaagtgaa gacagctgcc aaaactggta aaaggtacaa atgatcatgt tgtgccaatt
    41761 ccacccacaa gaaagtccct gtttttaaga aagatacccg tgtcaaggct tggaataggg
    41821 caatcataac tggcatctga attaagaggg gtaagagact ggcataaggg ttaaccccat
    41881 attttttgta aagggcttga ctttcttcag ccaacttcat ccgcgtttgt gtgtctttac
    41941 cagcgtattt cttttgtaat tctctaagct caggttggat gtcttgcatc ttctggcttg
    42001 atttgatttg catattaaac aaaggcatga gcatgagacg gatagtaagg gtaaaaagaa
    42061 taatgccaac accaattgaa ccatcaaagg aaagccattg aattgctctg gcaaataagt
    42121 aaaccaactg gtcccaacca ctagatgatt gtgccgttac ctcaccacga ccacaggcca
    42181 ctaataatag aactaagggg actattcttg caattttaat gtttttcttc actctcaaaa
    42241 cctttctcaa gcaattgtgc taactttaaa acatgatgta aattttgttg aagctcttga
    42301 tactccaaag actcgacacc cttacgggca atcaccacga aatcctctga cttcagctga
    42361 tgccctaatg ccatgataac atgacgtatc tttcgtttga ctgcatttct ggtgactgca
    42421 tttcctattt ttttaccgac agaaataccc acacggaagt ggtcttggcc tctatttaaa
    42481 tgataaatga caaattttcg atttgctgta ctttttccat ccttaaatat ggcttggaaa
    42541 tctttctcac gcttgacacg ataggtcttc ttcaaaattt aactccaata tctaaattat
    42601 taccattata ccacatcccc taaaaaatta aaaagcccta accctttcag attaagcctc
    42661 tttctgtact atttctagtt tttgtgcttc aactgcctct tgtcactcca tcttttcgta
    42721 gtatagttct tctttcgaca aaggaataac cttcagaaaa caaccataaa aagtcagaat
    42781 ccacaagacg tcagctactt atccctgtat ttacctatca aaaaacccgg caagccgggc
    42841 tttaatactg attttacaat cagctaatgt gatatccaaa caaagacaac tgacatcgtc
    42901 attttgtctg ccgagccatc atatcaaaaa tactatttgt ttatggagag agagaaaaca
    42961 atattttgat tgaattgggg attgattgct cgataaactc atgacttcgt aaatctttat
    43021 ttacactaat tattatagcg aaaaatgttt caataagagc atcatttcct gaaatgttgc
    43081 tttttcgtcc taaaatgtta ttgctctctt aactttagcg aagagcctcc caccgttcaa
    43141 acagacattt catttttaat cgtgatacca tacaagaatc accattttcg aaataaagga
    43201 gctgcttact cttatcaatt cgaacaacct tatctagatt cacaaggtag gatctatggc
    43261 acaaaaaaag tttcggtgct actgcttgaa tctcagatag attaccataa aactctaatc
    43321 tttctgtctg agtccataaa caaactttgt gaggagttgt ggctgtagca aagtataaaa
    43381 tatccttata gggcaatttt aatcttgtct gtggagtctc aaataaaaac atgtcctttg
    43441 actcacgact agacatcata tcgtaagtat atcggataca ttcttcgatt tgttctttaa
    43501 actgtttttg accacctgct ttatcaataa aatctagagc ggatacctta tatttaaaag
    43561 aaataggagc aaattctgaa tgagtggtga caaacacaat aacggcatta ggatcttttt
    43621 gtcgaatagc tgcagctaat tcaagcccac aacgagtata ttcaccaatt tcaatatcta
    43681 aaaaatacag ctgatggtct cctctttctt ggatactctc aaataatttt tgaggagtcg
    43741 agaacacttc aagctgatta catggtattc tagtctcttt taagatgcct actacgatag
    43801 attctatgcg tgtctgctgg ataaaatcat cctcaagaat aaaaatgttc atcatacttt
    43861 atctcatttc taacaattgt cttaatcgat aatggtcact tttagtcgaa agcgttattt
    43921 gggggtaact atctaaaaca gtcaaaaagt gggctgagtt ctgctgctga gcatcaaagc
    43981 gtttggctat atccacacga ttggtttttg tgctattttc aataataaat aattgcttgt
    44041 tatcttgttt aaagtatgca atagataaaa aaggacgtct actgcctttg gctgtctcaa
    44101 tagcattgtc cactagtcca gtaaaaagta caattaagtc gattaactta ataggtaaat
    44161 gatcgataac atctggaatc tcaatataaa gttcaatacc caaatactga gcttcaagca
    44221 atttggaatt catgatgctg cgaatcacag cctctttgat attgtctaaa gaagatattt
    44281 cataatttgt gcgcatcata gaagttgccg attgctgaat aaccgtgtca taaactctag
    44341 taatcagatc tatatcacca ctatcgatac tatcttttaa actaattaaa atattttcag
    44401 aatcatgttt aactgttctg atttctcggt aaagttgctc aatcgattga ttgtaatttt
    44461 caagatacgc aatacgttca ttttgtgctt gtgttaattt ttgtgacagc tgatctttag
    44521 caaatcgatc taatttcaca ataacccaaa taaaaatagc taaataaata a
//
LOCUS       DAUNLR010000009        44307 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUNLR010000009 DAUNLR010000000
VERSION     DAUNLR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44307
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.009"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            68..721
                     /gene="grab"
                     /locus_tag="VLL59_000484"
     CDS             68..721
                     /gene="grab"
                     /locus_tag="VLL59_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G-related alpha2-macroglobulin-binding protein
                     GRAB"
                     /protein_id="HER6508633.1"
                     /translation="MGKEIKVKCFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALADQA
                     DTLQSEEAAVVKADNAASDALEALADQTDALQSEEAEVVQSDNAASDAWEKAATPIAL
                     DVKKTKDTKPVVKKEERQNVNTLPTTGEESNPFFTAAALAIMVSTGVLVVSSKCKEN"
     gene            959..1501
                     /locus_tag="VLL59_000485"
     CDS             959..1501
                     /locus_tag="VLL59_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HER6508634.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEYYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1510..2793
                     /locus_tag="VLL59_000486"
     CDS             1510..2793
                     /locus_tag="VLL59_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HER6508635.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKK
                     TRQVRFPILDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2809..3669
                     /locus_tag="VLL59_000487"
     CDS             2809..3669
                     /locus_tag="VLL59_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HER6508636.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3671..4636
                     /locus_tag="VLL59_000488"
     CDS             3671..4636
                     /locus_tag="VLL59_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HER6508637.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPTSAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4747..6030
                     /gene="aroA"
                     /locus_tag="VLL59_000489"
     CDS             4747..6030
                     /gene="aroA"
                     /locus_tag="VLL59_000489"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HER6508638.1"
                     /translation="MKLRTNAEPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGVNTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6023..6514
                     /locus_tag="VLL59_000490"
     CDS             6023..6514
                     /locus_tag="VLL59_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HER6508639.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6722..8173
                     /locus_tag="VLL59_000491"
     CDS             6722..8173
                     /locus_tag="VLL59_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HER6508640.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8222..9613
                     /gene="rlmD"
                     /locus_tag="VLL59_000492"
     CDS             8222..9613
                     /gene="rlmD"
                     /locus_tag="VLL59_000492"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HER6508641.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFIADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLTKVQPVDLFPQT
                     HHVECVSLLEKRS"
     gene            9765..10543
                     /locus_tag="VLL59_000493"
                     /pseudo
     CDS             9765..10543
                     /locus_tag="VLL59_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044012.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            10628..11029
                     /locus_tag="VLL59_000494"
     CDS             10628..11029
                     /locus_tag="VLL59_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HER6508642.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(11134..12618)
                     /locus_tag="VLL59_000495"
     CDS             complement(11134..12618)
                     /locus_tag="VLL59_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HER6508643.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            12992..14212
                     /locus_tag="VLL59_000496"
     CDS             12992..14212
                     /locus_tag="VLL59_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HER6508644.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIIGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     TIGQLKAERYQQLR"
     gene            complement(14332..14697)
                     /locus_tag="VLL59_000497"
     CDS             complement(14332..14697)
                     /locus_tag="VLL59_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HER6508645.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            14812..15543
                     /locus_tag="VLL59_000498"
     CDS             14812..15543
                     /locus_tag="VLL59_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HER6508646.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKEVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
     gene            complement(15592..16934)
                     /locus_tag="VLL59_000499"
     CDS             complement(join(15592..16484,16484..16934))
                     /locus_tag="VLL59_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HER6508647.1"
                     /translation="MKFNQETKVKIYELRQMGESIKSISKKFDMAESDLKYMIRLIDR
                     YGVTIVQKCKNHYYSPELKQEIINKVLIDGQSQKQTSLDYALPTSSMLSRWIAQYKKN
                     GYTILEKPRGRPSKMGRKRKKNLEEMTEVERLQKELEYPRAENAVLKKPERIPLEGRS
                     KAQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDE
                     HKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADN
                     LIKRHFEGSKPYEKCYTDVTELALPERKLYLSPVLDGYNSEIIDFTLSRSPNLKQVQT
                     MLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILPSTSRKGNSPDNGMMDSFF
                     GILKSEMFYGLETTYQSLDKLEEAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFQ"
     gene            complement(17020..17883)
                     /locus_tag="VLL59_000500"
     CDS             complement(17020..17883)
                     /locus_tag="VLL59_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HER6508648.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGSSTVISLIFLLFGAVL
                     SLIGFSIYINRYYAYSLSEYLLYDEVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            18103..19245
                     /gene="tgt"
                     /locus_tag="VLL59_000501"
     CDS             18103..19245
                     /gene="tgt"
                     /locus_tag="VLL59_000501"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HER6508649.1"
                     /translation="MTDYPIKYRLIKTDKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDDLIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            19462..19773
                     /locus_tag="VLL59_000502"
     CDS             19462..19773
                     /locus_tag="VLL59_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508650.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            19777..20316
                     /locus_tag="VLL59_000503"
     CDS             19777..20316
                     /locus_tag="VLL59_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HER6508651.1"
                     /translation="MFTTKELVKMAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            20455..21234
                     /locus_tag="VLL59_000504"
     CDS             20455..21234
                     /locus_tag="VLL59_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HER6508652.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVERIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PEGIDPDNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            21234..21749
                     /locus_tag="VLL59_000505"
     CDS             21234..21749
                     /locus_tag="VLL59_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HER6508653.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(22363..23595)
                     /locus_tag="VLL59_000506"
     CDS             complement(22363..23595)
                     /locus_tag="VLL59_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HER6508654.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPKDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEPLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            23795..23893
                     /gene="ffs"
                     /locus_tag="VLL59_000507"
     ncRNA           23795..23893
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VLL59_000507"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            23995..24699
                     /gene="speG"
                     /locus_tag="VLL59_000508"
     CDS             23995..24699
                     /gene="speG"
                     /locus_tag="VLL59_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HER6508655.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     PPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEAVRIKKKQFTLQEFDFKI
                     RKFLMEKYNIYDSESRYTSGSLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKI
                     FNSEEISHFDIYLKTH"
     gene            25155..26504
                     /locus_tag="VLL59_000509"
     CDS             25155..26504
                     /locus_tag="VLL59_000509"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HER6508656.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(26852..28360)
                     /locus_tag="VLL59_000510"
     CDS             complement(26852..28360)
                     /locus_tag="VLL59_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HER6508657.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSLLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLVGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            29048..29719
                     /locus_tag="VLL59_000511"
     CDS             29048..29719
                     /locus_tag="VLL59_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HER6508658.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVAGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            complement(29818..30717)
                     /gene="galU"
                     /locus_tag="VLL59_000512"
     CDS             complement(29818..30717)
                     /gene="galU"
                     /locus_tag="VLL59_000512"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HER6508659.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(30750..31766)
                     /locus_tag="VLL59_000513"
     CDS             complement(30750..31766)
                     /locus_tag="VLL59_000513"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HER6508660.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            32064..32513
                     /locus_tag="VLL59_000514"
     CDS             32064..32513
                     /locus_tag="VLL59_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HER6508661.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            32506..34212
                     /locus_tag="VLL59_000515"
     CDS             32506..34212
                     /locus_tag="VLL59_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508662.1"
                     /translation="MLKEAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIESGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            34215..35999
                     /locus_tag="VLL59_000516"
     CDS             34215..35999
                     /locus_tag="VLL59_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508663.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTVTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            36117..36884
                     /locus_tag="VLL59_000517"
     CDS             36117..36884
                     /locus_tag="VLL59_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HER6508664.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            36994..37440
                     /locus_tag="VLL59_000518"
     CDS             36994..37440
                     /locus_tag="VLL59_000518"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HER6508665.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            37521..38882
                     /gene="radA"
                     /locus_tag="VLL59_000519"
     CDS             37521..38882
                     /gene="radA"
                     /locus_tag="VLL59_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HER6508666.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            39071..39568
                     /locus_tag="VLL59_000520"
     CDS             39071..39568
                     /locus_tag="VLL59_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HER6508667.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVREDMTKIRASSLISDDVVINGAVYDVDTGKM
                     TQVME"
     gene            39699..40409
                     /locus_tag="VLL59_000521"
     CDS             39699..40409
                     /locus_tag="VLL59_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HER6508668.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            40591..42036
                     /locus_tag="VLL59_000522"
     CDS             40591..42036
                     /locus_tag="VLL59_000522"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HER6508669.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            42431..43777
                     /locus_tag="VLL59_000523"
     CDS             42431..43777
                     /locus_tag="VLL59_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6508670.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLETYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            43774..>44307
                     /locus_tag="VLL59_000524"
     CDS             43774..>44307
                     /locus_tag="VLL59_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HER6508671.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRFSIIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGF"
BASE COUNT        13510 a         7812 c         9247 g        13738 t
ORIGIN      
        1 aattataatt tccaaattat cggtaattta atatgctaat gcatataaaa ataaaaaagg
       61 agaaacaatg ggaaaagaaa taaaagtgaa atgctttttg cgtagatcag cttttggatt
      121 agttgcggtg tcagcatcag tattagtcgg ttcaacagta tctgctgttg actcacctat
      181 cgaacagcct cgaattattc caaatggcgg aaccttaact aatcttcttg gcaatgctcc
      241 agaaaaactg gcattacgta atgaagaaag agccattgat gaattaaaaa aacaagctat
      301 tgaggataaa gaagctacga cagctataga agcagcaagt tcagatgcct tagaagcatt
      361 agcggatcaa gcagacactt tacaatcaga agaagctgcg gttgttaaag cggataacgc
      421 tgctagtgac gccttagaag cattggcgga tcaaacagac gctttacaat cagaagaagc
      481 tgaagtagtt caatcagata acgctgctag tgacgcctgg gaaaaagcag caactccaat
      541 cgctttagat gttaagaaaa ctaaagatac aaaacctgta gttaaaaaag aagaaagaca
      601 aaacgttaat acccttccta caactggtga agagtctaac ccattcttta cagctgctgc
      661 gcttgcaata atggtaagta caggtgtgtt agttgtaagt tcaaagtgca aagaaaatta
      721 gttgctattt gttctagcaa atgaaacaag ggaatcgaaa gattctcttt ttctgatatt
      781 taaaaatgct acagtttata atagcttgaa agactaaatg ttctcaaact cattagaaca
      841 agctttaata aaactaaccc agttgtatca aaggatagat aaagactaag actgttatag
      901 aatatttgca aaagatttgt tataatggac ccaatacagg tattgtgaaa ggtgtaatat
      961 ggatatttgg acaaagcttg cagtgtttgc tttttttgag actccgaaag taatattacg
     1021 gccttttcgc tatgaagatc attgggattt ttacagcatg gttaacgaca ctaaaaacct
     1081 ttattatgtt tttccagaac aaaaaactaa ggcagcaagt gactatcttt tagtacatag
     1141 ttttataaag tttcctttag gtcagtgggc aatagaagat aaagcaaccc accaagtaat
     1201 aggttctatt agaattgagt attatgatgc taaaacgcgt tgtgctgata ttggctattt
     1261 tttaaactat gccttttggg gacaaggaat tatgacagaa gtcgtaataa aacttgttta
     1321 tttatctttt cacgaatttg gtctcaaaac gttgcgtatt ataactcatt tagaaaataa
     1381 ggccagccag aaagtagcta aaaaagcagg ttttcaacta aaaacctgtt ttaaaggaag
     1441 tgatcgtaat actcataaaa tctgcattta taaaatgtac caactaacta atgataggtg
     1501 ataatcatta tgagcaaaca tcaagatatt ttagattatt tagaaaaact tgctattggt
     1561 aaaaaagtga gtgttagaag catttcaaac cacttaaaag taagcgatgg aacagcctac
     1621 cgtgctatta aagaggcaga aaatcgaggt attgtcgaaa ccaaaccaag aagtggaact
     1681 gttcgtattg aaaaaaaagg acgggttcgt attgaccgtc tgacctattc cgaaattgct
     1741 cggatcagtg attcggaagt gctagcggga catgctggtt taggacatga attcagtagg
     1801 ttttcaattg gtgctatgac tcaacaaaat attcgtcgtt acttggtcaa aggagggtta
     1861 ttaatagttg gggatcgtga aacgattcaa ctcttagctc ttgaaaacca taatgccatt
     1921 ttggtgacgg gcggatttcc agtatccaaa cgtgttattg aaatggcaaa taaccaacga
     1981 atcccagtta tggtaactca ttatgatacc tttactgtgg caacaatgat taatcacgcg
     2041 ctatctaata ttcgtattaa aacagatctc aaaacagttg aacaggtaat gatacctatt
     2101 acagattatg gttacctttg cgaagacagc tctgttgaag aattcaatac attaataaaa
     2161 aaaacacgac aagtcaggtt tcctatatta gattataaaa gaaaagtgat tggtgtagtt
     2221 agtatgcgtg atgtggtgga tcagttgcca acaactaagc ttaccaaggt catgtctaaa
     2281 aatccaataa cggctagacc aaatactagt cttgctaata ttagccagaa aatgatcttt
     2341 gaagatttaa acatgttacc tgtcactgac gaagaaaata atttacttgg tatgattact
     2401 cgtagacaag caatggaaaa tttgccaaat caccaaccaa ataaccccta tacttatagt
     2461 gagcaaatac tttctaacct tgaagaaacg gttgattatt accaagtagt agttgagcca
     2521 acaatgattg atagtgctgg taacatgtca aacggtgtta tttcagagtt cttaaaggaa
     2581 attagtatca gagccctcac gaaaaagcac caaaaaaata tcattatcga acaaatgatg
     2641 gtatactttt tacatgctat tcaaattgag gatgaattaa aaatatatcc taaaatcatt
     2701 actgaaaata gacgaagcag caccattgat attgaaattt ttgtggatga tcaagtgatt
     2761 gctaaagcta ttattacaac gaaaataaat tagaggagta acaaaacaat gataacatta
     2821 aaatcagccc gtgaaataga agcgatggat agagcaggag acttcttagc aggtatccat
     2881 attggcttaa gggatattat taagcctggt gtggatatgt gggaagtgga agcatatgtt
     2941 cgtcgccgtt gtaaagaaga caacgttctt cctttgcaaa taggggttga tggtcacatg
     3001 atggactatc cttatgcgac ctgttgtggt ctaaatgacg aagtagcaca tgcctttccc
     3061 cgtcattaca ttctgaaaga aggggatttg cttaaagttg acatggtact cagtgagcct
     3121 ttggataaat caattgttga tgtagcagct ttagattttg ataacgtgcc tgagatgaag
     3181 aaatggacag gatcttatac cggtggttta gctgactctt gttgggctta tgctgttgga
     3241 acaccgtctg acgaaataaa gcaattaatg gatgtcacca aagaagccat gtaccgtggt
     3301 attgaaaaag cagtaattgg caatcgtatt ggtgatattg gcgcagctgt tcaagaatac
     3361 gctgaaagct tcggttatgg tgtcgtgcgt gatcttgttg gtcacggtgt tggtcctaca
     3421 atgcatgaag agccaatggt accaaactat ggaacagcag gtcgtggact tcgtctaaaa
     3481 gaaggcatgg tcttgactgt tgagccaatg attaatacag gaacttggga aattgatacc
     3541 gacatcaaga caggttgggc tcataaaacc ctagatggtg gtttatcttg ccaatacgaa
     3601 caccaatttg tgattactaa agatggtccc gttattttaa caagtcaagg agaagaaaga
     3661 acttactaaa atggcagaaa aaaaatggtt tgataaggta ctgtccaagt ggcagtatga
     3721 acccattcaa gtctttatga ggcatttaca aagtgcagaa atggatttat ctgccattgc
     3781 ggttgcgtat taccttatct taacggcctt tccattaatt gttattgcag ccaatatttt
     3841 tccttacctc aatattgata ttgctgattt gttacgttta atgaagcaaa atttgcctaa
     3901 agatattttt agaccgactt ctgcaattgt agaaaatatt ttctctaaac cgtctggaag
     3961 tgttttggga gtagcgactt tgacaggatt atggacaatg tctcgaagtt tgacatcgct
     4021 gcaaaaagct attaataaag cctatggcgc ttctcagcat cgagatttct ttatcggaca
     4081 cttggttggt ttgttgacca gtttaattat tttattttta ttagcctttg ccttaatctt
     4141 ttcaacattt tctaaagctg ctattcaagt gctggataag cattaccatt tgagtgataa
     4201 tatcacaacg attttcttac tcctcattca acctattaca gttttgatta tttttgttgg
     4261 cttgatgcta ctatattttt tattacccaa tgttaagatt aaaaaaattc gctacatttt
     4321 accaggaacc ctatttacat cttttgtgat gacatttttg agtaatctgg ttggcaatta
     4381 cgttgtgtat aatgttgagc ggatggtaga tattaaaatg tttggttcag ttatgatttt
     4441 tatcatcatg ctatggttta ttttcttagc aagaatcctg attttaggag ctatatttaa
     4501 tgcgacctat caagaaatgt ccttggggaa attagaaggt cgtagtggtg atatgatcgc
     4561 tatccttaaa aaaacacttg ggaatgattc agatctatct ccttcacagt ctatcgaaga
     4621 tagtcacact gattgataca aaaaagataa taagtcgtgg agtgagaaac tattttcttg
     4681 cttcattttt tatgaggatg aatagaaaat cattgatctt agcaaataga aaggcagatg
     4741 aaacggatga aattgcgaac aaatgcagaa ccattacagg gaacgattca agttccagga
     4801 gacaagtcca ttagtcaccg ggcagtcata ttaggagccg ttgctaaagg ggaaacacga
     4861 gtaaaaggac tcttaaaagg agaagatgtg ctttccacga ttcaagcctt taggaatttg
     4921 ggagtccgta tcgaagaaaa agatgaccag cttgtgatag aaggtcaagg ttttcaagga
     4981 ttgaccgctc cttgtcagac acttaatatg ggaaattctg gaacctctat gcgcctcatt
     5041 gctggcttat tggcaggtca accttttagt gtcaaaatga ttggcgatga aagcttatcc
     5101 aaacgtccta tggatcggat tgtttatccg ttaaagcaaa tgggggttga gatatctgga
     5161 gaaacagata ggcaatttcc tccactacaa ttgcaaggta atcgtaattt acaaccaatc
     5221 acatatacct tgcctatctc ttctgctcag gttaagtcag ctattttatt agcagctttg
     5281 caagcaaaag gaacaacaca ggttgttgaa aaagagatta ctcgaaacca tacagaagaa
     5341 atgattcaac aatttggtgg acgattgata gttgatggta aacgcattac tttggtggga
     5401 ccccagcagc tcactgctca agagataact gtccccggag atatttctag tgcagctttt
     5461 tggcttgtcg ccggcttaat tattcctggt tcggagctcc ttttaaagaa tgttggagtc
     5521 aatccgacac gaacagggat tcttgaagtg gttgaaaaaa tgggagcaca gattgtctat
     5581 gaagatatga ataagaaaga gcaagtaact agtattcgag tggtatattc tcacttgaaa
     5641 ggaactatca tatcaggagg tcttatccct cgattgattg atgaacttcc catcattgca
     5701 cttcttgcaa cccaagcaca aggaacaacc tgtattaaag atgctcaaga attacgagtc
     5761 aaagaaacag atcgtattca agtagtaact gatattctta acagtatggg agctaatatc
     5821 aaagcgacag cagatggcat gattatcaaa ggccctacgg tactatatgg ggttaacaca
     5881 agtacctatg gagatcatcg tattggtatg atgacagcaa ttgcagcctt gcttgttaaa
     5941 caaggacagg tccatttgga taaagaagaa gccatcatga cgtcttatcc gacgtttttc
     6001 aaagatttag aaaggctgtg tcatgactaa agtgttattg ggatttatgg gagtggggaa
     6061 aacaacggtt tcgaaacacc taagtatgca ctgtaaagat atggatgcta ttattgaagc
     6121 taaaatcggt atgtctattg cagctttttt tgaacagcat ggagaaatag catttcgaac
     6181 aattgaaagt caagtgttaa aagatctatt gtttgcaaat gataatagtg tcatcgtaac
     6241 aggtggcggt gtagtggttt tacaagaaaa tcgacaatta ctgagaaaaa atcaccagca
     6301 taatatttta ttggtagctt cttttgaaac tttgtaccag cgtttaaaac atgataaaaa
     6361 gtctcaaaga cctctatttc ttaagtactc taaggaagca ttttatgaat tttatcaaca
     6421 acgtatggta ttttatgagg gactttcaga tttagtaatc agagttgacc atcgtacgcc
     6481 tgaagaagtt gccaacatca ttgagggtta ttagtaggtc attgtcgtaa tctgatattt
     6541 atggttttaa acaggtatct gtctaaagca cttcttatgg caagttggct ttattaaata
     6601 ttaggaaata atcttgatta ttctataatg attaaaattt tgagaggaca atctggctaa
     6661 tataggttat aatggtagta ttcgttaaaa gtgcaattgt aatactaaga gatgataaga
     6721 tatgacaaaa taccccatgg gtggccttag tcaccatgaa gaattacgtt atttttatct
     6781 cctaaggaat ttgagttacc ttagtgagaa tgaaaaaaaa gagtttgctt ttttaaaatc
     6841 taaattggaa attggtcgag cttatgcgcc ttctaagcag cattatagga agtcaaaacg
     6901 gcaagaacct tactttgaag atgactacta taacgactac tcaccaaatg atttactaga
     6961 agatgatgac gtcaatcatg actcttcttt tgttccatat ggtttaccga tatatcctaa
     7021 agaagacaga tatttaaaca aaaaaacaaa acttacagct cgtagaccta tagatgctcc
     7081 gcagcctatt gatgaagacg atgctttttt aacagaatct gttgctcgtt gtgctcttcc
     7141 tagatctcaa aaaagaaagc ataagaaaaa aggatgtatg aaatggtttt ttaacattct
     7201 tggcttattg ctaatgactg tgcttatggg gttagggttg atgtttgcaa aaggggtttt
     7261 tgatatttct actaataaag ctaattataa accagctgtt tcccaagctt ttgatggtca
     7321 agaaactcaa gatggtacga acattctggt tttgggttct gaccaacgag ttactcaagg
     7381 ttctacagat gctcgcacag ataccattat ggttgtcaat gtcggcaacc atgctaaaaa
     7441 aataaaaatg gtctctttta tgcgtgacac tttgattaac attccaggat acagttataa
     7501 tgataattcg tatgatctta aattaaatag tgcatttaat cttggagagc aagaagatca
     7561 ccacggagca gagtacgttc gacgggcctt aaaacataat tttgatatcg acattaagta
     7621 ttatgtgatg gtagattttg aaacatttgc agaagctatt gacaccttgt ttccaaatgg
     7681 tgttaagatt gatgccaaat ttgcgacagt aggtggtgta gctgttgact ccgtagaagt
     7741 tccagatgac ctgcgaatga aaaatggggt tgttcccaac caaaccatcg aagttggaga
     7801 acaacgcatg gatggtagaa ccttgctcaa ctatgctcgt ttccgtaaag atgacgaagg
     7861 agatttcgga cgaaccgtcc ggcagcaaca ggttatgtca gctgttatgt cccaaatcaa
     7921 agacccaact aaactcttta cagggtctgc ggctattggt aaaatctatg cgctgacttc
     7981 gaccaatgtt tcttttccat ttgttgttaa aaatggtgtt tctgttttag gaagtgggaa
     8041 aaatggagtt gagcacgtga ccatcccaga aaatggggat tgggttgacg aatacgatat
     8101 gtatggagga caagcccttt acatagattt tgataagtat cagaaaacgt tagccaaatt
     8161 aggtctgcgc taagatatgg tataatggag agtaactaaa gttgctcttc ttttttgagc
     8221 aatggttagc cctagaaaag gaaaaagaat aagaatgttg aaaaaaaatg atattatcca
     8281 agttgctatt tcagatttaa gccatgaggg agcaggtgtc gctaaacacg atggttttgt
     8341 tttctttgtt gataatgcct tgccagaaga agtgattgac atgcgtgtct taaaggtcaa
     8401 taaaaacagc ggttttggca aagtagaagc ctatcattac ctgtcgccag ctagaaatgc
     8461 agatgtcaat ttaacttatt tgcgaacagg cattgcagac cttggacatc taacttatga
     8521 agaccaactg actttcaaaa agaaacaagt tcaggacagc ctctataaaa ttgctggaat
     8581 cagtgacgtg acagtcgaaa gcacgattgg gatgacagaa cctttagctt accgaaataa
     8641 ggctcaagtt cctgttagac gtgttaatgg tcagctagaa acaggctttt tccgcaagca
     8701 ttctcatgac ttgattccta tttcggatta ttatattcag gacaaagaga ttgatcgtct
     8761 cattaatttt acccgtgatt tattacgccg ctttgatatt aaaccgtatg acgaaacaga
     8821 acaaacaggt ctcttgagaa atattgttgt tcgccgaggc cattactctg gagaaatgat
     8881 gctggtctta gtgactacac gcccaaaagt tttccgtgtt gaccaagtca ttgaaaaaat
     8941 cgttgaagct tttccagcag tggtgtctat tattcaaaat attaatgata agaacaccaa
     9001 tgcaatcttt ggtaaagatt tcaaaacgct ttacggcaag gataccatta ctgatagcat
     9061 gcttggaaac aactatgcca tttctgctca gtctttctac caagtgaata cggttatggc
     9121 agaaaaactc tatcaaacag ctatagcctt ttcagacctt tctaaagatg atattgtgat
     9181 tgacgcctac tcaggtatcg gaaccattgg cctatcattt gctaaaacag ttaaagctgt
     9241 ttatggtgtt gaagtgattg aagcagctgt tagagatgct caacagaacg ccgctcttaa
     9301 tggcatcacc aatgcctact ttatcgcaga taccgcagaa catgccatgg caacatgggc
     9361 gaaagatggc attaaaccaa gtgttattct ggtagacccg ccacgaaaag gcttaacaga
     9421 aagtttcatc caagccagcg tggcaatggg accacaaaaa atcacctacg tttcctgcaa
     9481 cccagccacc atggcgcgtg acatcaagcg ttatcaagag ttgggttaca aactgaccaa
     9541 agtacagccc gtagatttat ttccccagac gcatcacgtg gagtgtgtaa gtttacttga
     9601 gaaacggagt taaagagtcc gcctcactct gttatttcaa ggtgagacgc tcaaaaggtc
     9661 cactggacct tttgactccc gcagacccat cacgtcgagt gcgtagtgtt gctaatcaag
     9721 gagtaaggta gctgcctcca catgacaaaa ataaggagaa acgaatgcct attaccaaac
     9781 atgagattcc ccttttagaa tgtgatagta atccatcagc cgtcattatc tagctattta
     9841 gcttccagct aagtgtgtct atgctttctt agaagacgag attgaagctt ttgctttaga
     9901 ccatcaaggt aaaaaagtag cagaattcat ttcagccaca aaggtttacc ctgtttatca
     9961 gatatcttat aaaggtcaag acatttgcct agctcaagct cccgttggct cagctcctgc
    10021 ggcgcaattc atggactggc tgattggtta tggggttaaa gaaatgatca gtacaggaac
    10081 ctgtggcgtt ttggttccta tcgcagaaaa ccgtttttta gtgccagtta aggctttgcg
    10141 agatgaagga acaagttatc attacgtggc accatctcgt tatattgata ttgatcctaa
    10201 gatgcttaga ctgattgaga aaacgctttt agcacagggg ttagcttatc aagaggtcat
    10261 cacctggtca acagatggtt tttaccgaga aaccaaagaa aaagtggctt atcgccagga
    10321 agaagggtgt tcggttgttg agatggaatg ttctgcctta gcagcagtag ctcaattaag
    10381 aggcatcctt tgggggtaac tcttatttac agcagatact ctagcagatg tagaggttta
    10441 cgatcaacgc aactggggcg ctgattcctt tagttttgcg ctctatttat gcttggaagt
    10501 gctcaatacg ctaggaaagg atggaaaggc tacttatttt tgaaacatga gctctgcctt
    10561 ctgttcctat ttgtagtata atgaggcttg tattgctttt agactaagct tagaaaagag
    10621 aaaaacaatg tcagatttaa cacaagagat gaccttaaat gttattagta tttttgataa
    10681 ttaccaaatt gaacttgctg aaaaaggaca ccttatttta agtactgaag tgactgagac
    10741 ggctttgaat tattatggga atgcccatgg tggttatctt ttcaccctat gtgatcaagt
    10801 aggtggtttg gttgctagaa ctactggcgt agaatctgtc accttacagg ccaatgctaa
    10861 ctatttaaaa gcagggcaca agggagacaa gctgatggtt gaaggtcgat tggttcatgg
    10921 aggtcgaacc acgcaggtgg ttgatgtgac gattcataac caaacaggag ctcttctaac
    10981 aaaaacaagc ttgaccatgt ttgtgactgg ccgacgtcat aacgggtgat taatgaatca
    11041 ataaaggaaa aaagtcccaa ctctctgaga attggggctt ttttccttta ttgagagata
    11101 ccataaatca cccgttagac gggtggttat ggtttattta cggtaaagtt tgtgatgttg
    11161 gtaaacaggg tcaaaggtaa tatttacccc aagttttcgg agtacatttt tatcttcttc
    11221 ggttaagata acggtagaat gggcttcgct acctttcaaa ttgccgagtt ctttcatggc
    11281 tagattagct tcttcactag tcatagcagt aatggctaac gcaatcagaa tttcattgga
    11341 atgaagccgc ggattgtgac tgcctaagtg gttcactttg agtccttgaa taggtttcac
    11401 gtattcgggt tcaatcaaat gagtggtttt atcaatcttt gccaaggttt taatcgcatt
    11461 gatgataaca gctgcagttg gtccaaagag ttcagatgtt ttacctgtca caatttgccc
    11521 atttggtagt tggagagcaa gggcaggttg gcctgtttgc tctgcttttt gatgagcagc
    11581 tacagtaacg tgacgatcgt caggggtgac accgatatca ttcatcaaga gctcaatttt
    11641 tttgacagca gattctgtga cccgctctgc cttaaaatcc acgagggttt ggtaataacg
    11701 acggatgatt tcttgtttag aagcttcgat agcagcttct tcattgacga tagaaaaacc
    11761 aaccatgtta acacccatat cggttggtga ggcataagga gacttgctca aaatacgctc
    11821 gaaggtccga tttaagacag gaaagacctc gatatcacgg ttgtaattaa cggccgtttt
    11881 gccataagtt tccaaatgga aggggtcaat catattcaca tcatctaggt ctgccgtggc
    11941 tgcctcataa gccagattga cagggtgatg aagaggaaga ttccaaactg ggaaggtttc
    12001 aaatttagca tagccagact taaccccatt gatttggtcg tgatacattt gggacatgca
    12061 agtggctaat tttccagacc cagggcctgg tgctgtaaca acgataaggt tacgactcgt
    12121 tttgatgtaa tcatttttcc ccatcccctc agatgagata atatgattaa tatctgttgg
    12181 gtagcccttg ataggataat gcaggtaaga agcaatgcca tttttttcga gttgcttgcg
    12241 aaaggcatct gcagcgggtt ggttattgta ttgggtaata acgacagaac ctacgtaaat
    12301 atctaacgtg ttaaatttgt caattaagcg aaagacttct tggtcataag aaatgcctaa
    12361 atcaccacgc gctttagaat gttcaatatt attagcgtta atggcaatta caatttcgac
    12421 ttgttctttg agctctttga gtaatttaat cttattgtca ggttcatagc caggaagtac
    12481 acgggcagca tggtaatctt ctaacatttt accaccaaat tccatgtaaa gtttgccatc
    12541 aaattggctg atacgttcta aaatatgatc tctttgcaag tttaaatact tgttagaatc
    12601 aaaagcaata gtcttcattt tttcacctct gtaaagcatt ataacaaaga aattccaaga
    12661 aagaaaaggt tttttgcagg gatacctcat tttgtgactt tttaaaaaaa cttaggcttg
    12721 gttcttagaa gaaaaatgta tccgctatgt tcaaaagaac ttgacaatta aaatgagctt
    12781 tactatacta gtaacaatta aatactactt taaacatgtt ccgtgaagca tgaaagtctt
    12841 aacagtaaag agagtttttt tgtcatctct tattatttag tgaactttga tggacttgcg
    12901 gacttgtttc caagtctttt tttgaccttt ggacaaaggg tattcaatta attaaggtag
    12961 tcagtgagct actattaaga aggagacaat tatgtcaaca ttatcattgg acaccacaaa
    13021 taagcgagct ttagtggcag ctattgcagc ttcaggaacg gatgacttga atgtcatgtt
    13081 tcttgccttt tccatgtctt ccattatgac agacttgggt cttagtggca ctcagggtgg
    13141 ctggattgcg accattacca atttaggaat gttggtggga ggcctcttat tcgggttgct
    13201 ggctgatagg caccacaagt ttaaggtctt taaatggacg attttactgt tttcagtagc
    13261 aacaggatta atttatttta cccagtcttt gccctacctg tacctgatgc gatttattgc
    13321 tggcatagga gttggaggtg agtacggtgt agccattgcc ataatggcag ggattgtacc
    13381 accagaaaaa atgggtcgga tgtcttcttt aaatggtatt gctggccaac ttggctccat
    13441 tagttcggct cttttagcag ggtggctggc tccaagtcta ggctggcgtg gcctttttct
    13501 ctttggatta cttccgattc tcttggtgat ttggatgact ttagccatag atgaccaaaa
    13561 aatttgggat cattatgggc aagaagagga agaatgcagt caaccaatta aaatcaatga
    13621 actattcaaa acaaaatcct taacagctca aacccttgct ttaatggtca tgacgactgt
    13681 gcagattgcg ggctattttg gaatgatgaa ttggttgcca accattattc aaacaagctt
    13741 aaacctttca gtaaaaagtt cgtccttgtg gatggtggct actattgtcg gcatgtgttt
    13801 ggggatgctg tgttttggtc agcttttaga ttgttttggt ccacgtctga tttattccct
    13861 ctttttatta gcatcatcta tttgtgttta cctttttcaa tttgccaatt ccatggcgag
    13921 tatggttatt ggaggtgcta ttatcggttt ttttgtcaat gggatgtttg ctggctacgg
    13981 ggctatgatt accagacttt atccccatca cattcgatcc acggctaata atgttatttt
    14041 gaatgttggc cgtgctctag gaggattttc gtccgttgct attggtagta ttttagatgc
    14101 ctcaggtatt tcaatggtca tgattttcct agcttctctg tatgtgatta gttttggagc
    14161 catgtggact attggtcagt taaaagcaga acgctaccaa caattgcgtt agcaaagaga
    14221 tgggtgttag tatttgagtt actttcactc acaaagctat tttattgatt gagataacca
    14281 aaaaggtaag cacttaggga ttgcttacct ttttggttct tttcttttgt tttactccgc
    14341 tactttggcc ataaaatgtt tactgttcac cctaactcta gtatgacagg cttttccaat
    14401 gagttgttct cccacaaaag cttccaagcg gaaatcgtat tttcggcctt cttctttaag
    14461 ggctgtaatg atgattgtaa caggatctcc aatggctgaa gctgccaaat gttggatagc
    14521 tatctcgctg ccaaccgttg taaagtcact gtcgagctgt tcttgggcaa ataagtaaga
    14581 agcattttcc ataaaagcaa caagagcagg agtagctagg acattcagcg ttcctgagcc
    14641 catggcttta gccgaatgat tgggacgggt ttcataagtg tgagaataaa tagtcataag
    14701 ttaatctcct cgtttctata agcctattat aatatattaa gcgcttacag tcatgaaact
    14761 actgtttttt tatgttatac ttaataatga attttctttg aaagggttat gatgcgctta
    14821 gataaatttt tagtggcaac tggtgttgga actaggagtc aagtcaaact tctcttaaaa
    14881 aagaaggcta ttttcgtcaa tcaaaaggtt gaaacctctg ccaaagcaca cattgatgaa
    14941 tacaaggatt tggtgacgta tcaaggcacg cccttggtct atgaatcctt tgtttattac
    15001 ctgttaaaca agccgtcagg gtatgtgtca gcaacccagg acagacagca ggctactgtt
    15061 atggagttgt tagatgacac ggctaggcaa aaagcagttt ttcctgtggg taggttagat
    15121 aaggataccc gtggactttt gctcttgacc aataatggac aactagccca tgacctttta
    15181 tcccctaaaa aacatgttac gaaagagtac ttggctaaag tagcaggcat catgactgaa
    15241 gctgataaag attattttgc tagaggtatt tccttaaagg atcaccagtg cctacctgct
    15301 catttagaag tgcttgctag tgatttacag cagcaaacaa gtttggttaa aattaccata
    15361 caagaaggaa aattccatca ggtgaaacgc atggtagcag cctgtggaaa ggaagtgctt
    15421 gacttacagc gtctcagcat gggaccatta aaactagacc ctagccttgc agaaggggag
    15481 tttaggcgcc tgacgcctga ggaattgcaa agcctggcac cttattgtca gagctcacta
    15541 taaaaagcaa cctcccctgt cagtactgac cccaaaaagt tggacaaata attattgaaa
    15601 ggatttagtt ctgtattgga caggactaag tccttttagt tttgctttga ttcgtttgtt
    15661 gttgtagtaa aaaatgtaat ctgtaatagc ttcttcaagc ttgtcaagtg attgataagt
    15721 tgtctcgagt ccataaaaca tttcagattt gagaatgcca aagaaggaat ccatcatgcc
    15781 gttatccggg ctattccctt tgcgggacgt ggatggcaaa atacctttag actctaaaaa
    15841 atcatggtag gactggtgtt ggtattgcca cccctggtca ctatgaagaa tagttccgct
    15901 gtatgaatct gctggaaaag tcttctcaag catggtttga acctgtttca agttaggaga
    15961 ccgagataga gtgaaatcaa taatctcact gttatagcca tcaagaacag gtgataagta
    16021 gagttttctt tcaggtaagg ccaactccgt cacatcagtg taacattttt cgtaaggttt
    16081 agagccttcg aagtgacgtt taatcagatt atcagccttc ttaccaacct ctcctttgta
    16141 agaagaatac ttgcgcttcc gacgaatgcg ggctgctaag cccatgactt tcatgagacg
    16201 ttgaactttc ttatgattga ccacaaatcc tcggttacgc aactccatat gaatccgacg
    16261 ataaccgtaa ttacctttat gctcatcata aatctctcga atcacatgct ttagttctat
    16321 atccttatct ccttgagcta gtcgcttcac ttgatagtaa taggtggagc gtgataaatc
    16381 aaggatttca agtagcatct ctaagggaaa ttgattcctt aatgcttgaa tgatttctgt
    16441 tgctctttga gctttacttc gtccctcaag cggtattctc tcagcttttt tagcacagca
    16501 ttctccgctc tagggtattc taattccttc tgaagacgtt caacctctgt catctcttcc
    16561 aaatttttct tacgtttacg ccccatctta ctcggtctcc ctcttggttt ttcaagaata
    16621 gtataaccgt ttttcttgta ttgcgctatc caccttgaga gcatactaga agttggtaaa
    16681 gcataatcta aggatgtttg tttctgagat tggccgtcaa tcaggacttt atttattatc
    16741 tcttgcttca gttctggaga ataataatga ttcttacatt tttgaacaat ggttacccca
    16801 tacctatcaa tcaagcgaat catatatttg agatcggatt ctgccatatc aaactttttt
    16861 gatatggatt taatggactc tcccatttgc cgtaactcat aaatcttaac tttcgtttct
    16921 tgattaaatt tcataaaaaa atagcacccc aaccgttaga ttttgtgtct aacttttggg
    16981 gtgcagttca agggctattt ttatggatgg aggatttatt tagtcttttt gatcgtcata
    17041 catcatagga gtaggctttt tattaagctg atgaaggctt aaatgttctc cttcaattgg
    17101 gtcatctttg tctttgaaac gtttcttgag ttgatcataa aaaatgacat tggctgttgt
    17161 aaaatatggt aaaagataga tattaagtaa cccaaaagta acaatattca gtagaaacca
    17221 accggtgaag ctaagttgta ggaaaaaaag cttccattta taacctttca tcatagctac
    17281 acttgtttca atgacggcta tagctcctag ataagtcccc tctttaacct catcgtagag
    17341 aaggtattct gatagactat aagcgtaata acggttgata taaatactaa aaccaattaa
    17401 ggacaaaact gctccaaata gtaaaaagat cagtgaaatg actgttgagc tacctgattt
    17461 agcattgacc aaaaacgctg aaagtccgga aaggaaaata aagaggccaa aaaaccaaat
    17521 tagtgaccag atgagaaaga atagccactt agtgatcgct aaaaccagca ggttcccaaa
    17581 gaattctttt gagaaggctg ttgttgattc ggcaaaagaa actttctgac gaaaatgcct
    17641 aacaacatca atcatcgtaa aggatgctga taaaatgaaa aggctaagga taagtcctag
    17701 tagtaatggg aaataactag ccgctagcga gacttcaata ccactagata ggacgtaacc
    17761 ttgatgaatc tcaataccga aatgaaacat aaagagaagg gttggaatta aaaatagtaa
    17821 atacttgcca gagagatttt ttaacgtgtc tctagcctgg cctttgattg ctttaattga
    17881 cataacagac tcctttattt cattatacca taaaacaaaa tgagacagct aaccattatt
    17941 ttgactatac ttttttggga aagcatgaca aattatggat tttttgataa aatgataggc
    18001 gctagaacaa catgtcatct tgaagccctt catgtatgat ggaaactcag gcagatcaaa
    18061 aaagctcaag actgtttatc ttgatagcaa ggaagaaagc acatgacaga ttatccgatt
    18121 aagtatcgcc ttatcaaaac agacaagcac accggtgcac gcttgggcga aattatcacc
    18181 cctcacggga cctttccgac accaatgttt atgccagtgg gaactcaggc tactgttaaa
    18241 acacagtctc cagaagagtt aaaagctatt gggtcaggga ttattttatc aaacacttat
    18301 cacctctggt tgcgtccagg agatgatttg attgctcgtg caggtggtct gcacaagttc
    18361 atgaattggg atcagccaat cttaaccgat tcgggtggtt ttcaagttta ctctttagcc
    18421 gattcacgaa acatcactga agaaggagtg actttcaaaa atcacttgaa tggctcaaaa
    18481 atgtttctat cacccgaaaa agccatttcc attcagaata accttggctc agacatcatg
    18541 atgagttttg acgagtgccc gcaattttac caaccttatg attacgtgaa aaaatccatt
    18601 gaacgtacta gccgttgggc agaacgtggc ttaaaagccc atcgtcgtcc tcatgaccaa
    18661 ggattatttg gaattgtgca aggagctgga tttgaggacc ttcgtcgtca gtctgcggca
    18721 gatttggtgg ctatggattt cccaggttat tctattggtg gtttagctgt tggggagagc
    18781 catgaagaaa tgaatgccgt ccttgacttt acgactcccc tcttaccaga aaataaacct
    18841 cgttacctga tgggagtggg agcaccagat agcttgattg atggtgtgat tcgtggtgta
    18901 gatatgtttg actgtgtctt gccaacgcgt atcgcccgta acggaacttg tatgactagt
    18961 gaggggcgtc ttgtggttaa aaatgccaaa ttcgctgaag attttacccc acttgatcat
    19021 gactgtgact gctacacttg tcaaaactat agccgtgcct acattcgtca cttgctaaaa
    19081 gcggacgaaa cttttggtat tcgtttgaca agctaccaca acctttattt cttggttaac
    19141 ttgatgaaaa aagtacgtca ggctattatg gacgataact tacttgaatt ccgccaagat
    19201 tttcttgaac ggtatggtta taataaatca aaccgtaatt tctaattaaa aatgctatga
    19261 tcctggaact gagggcgatc tatcgtcttt ggtttcagtt tttttgtata gacggatgtc
    19321 ctattgcttt caactgatag gtcactcttt aaagggaagt tcttgtttta cgtgttcttt
    19381 ttcagaaaac agttaccctt ttgtaaaaat agagttgaca aatcataagc ttttgattaa
    19441 actgttacaa gaggatgaga tatgacggac tgttttggaa ttgaccttga ccaagagtat
    19501 cggtgcctac attatcatac cccgcttgat attgttgggc tcaaatgtgc tttttgtcag
    19561 acttattatg cttgttacca ttgccatgac cagttaacag atcatgcctt tgtgccaaca
    19621 ggacatcaag aaacatctcc tgttatttgt gggcattgtc gaaagctctt gagcctagct
    19681 gagtatggtt gtggatgctg tccttattgt caaagtccct ttaatccagc ctgtcatagg
    19741 cacaaggata tctatttttt aaaggagtcg taacagatgt ttacaaccaa agaacttgtt
    19801 aagatggcta tgatgaccac tttgattatt attttaggct ttattcctgc tatcccgcta
    19861 ggctttatcc cagtccctat tgttttacaa aacttaggtg tcatgttggc tggattgatg
    19921 ctgggtggta aaaaaggaac cttatctgtt ttcttatttt tagtgattgg ccttttctta
    19981 cctgttttct caggctcacg aacaaccatt ccagtattga tggggccatc tgctggctat
    20041 gttattgcct accttcttgt gcctattgtc ttttcattac tttaccgcaa ctggttctca
    20101 aaaagcacgc cattggcatt cctagctctt ttaatctcag gagttgtact ggttgatgtt
    20161 ctgggtgcta tctggttggc agcctacact ggcatgtctc ttgtgacatc gcttttgtca
    20221 aacttggtct ttattccagg agataccatc aaagcaatca ttgcgaccat tatcgctgtt
    20281 aaatacaaag atagtttttt gaatacaaaa cagtaatcta atcatcaaat agttaagttg
    20341 tgttgaacag gtcttggcag atttatctgc taggacctgt ttttggtggg tctcaatcct
    20401 ctttgacact aatttttgtt ataatagtag gaaagcaaga aagaagggtt tgagatgaaa
    20461 ttaaccacct tagggtcttg gggagcctat ccctatcaag atgcaggcac aacctcttat
    20521 ttggtcacag gacatgacgg ctttcagtta ttgatggatg ctggtagtcg agcgctcaat
    20581 gagctggaaa aagaaatcag tcctctcgat ttggatgcag tgattattag ccattaccat
    20641 ccagaccacg tggccgattt aggcgtgttg cgccattatt ttcaacttta tcctaaacac
    20701 ctgtggcagc ctaaagtatt gcctatttat gggcatgatg aggaccgaca cgaatttgct
    20761 aaattaagca ttcctgatgt ttcagaaggt agagcctatg atgtcactgg agttgaacgg
    20821 attggtcctt ttgacattac ctttcttaaa acggttcatc cagttgtgtg ctatgccttt
    20881 cgaattgtag aaagagcgac tggtcaggta cttgtcttta ctggagacag tggttatttt
    20941 gaaggattgg cagacttcgc aaaagaagca gaccttttct tagcagatgt ttacttatac
    21001 gaaggcaatg aaaatcatat ggcccatttg accagtaagg aagcaggact aatggctagc
    21061 caggcaggtg ttaagaagct tgtcttgacc cacatgccac cggttcctcc agaaggtatt
    21121 gatcctgaca atcacttgga agtgttgagg caagaaacac aagcctatgc aggtaatatt
    21181 cctgttgacc ttgccttacc acacaaatct tggaacttgg ggagtctttc ttgatgccat
    21241 atagtttaga agagcaaact tatttcatgc aagaggcttt aaaagaagcc gaaaaatcct
    21301 tacagaaagc tgaaatcccc attggctgtg tcattgtcaa ggatggtgag attattggtc
    21361 gtgggcacaa tgcgcgtgaa gagagtaacc aagccattat gcacgctgaa atcatggcta
    21421 ttaacgaggc taacgctcat gaaggcaact ggcgtttatt agacaccaca ctctttgtga
    21481 ccatcgagcc ttgtgtgatg tgtagtggtg ccattgggct agcaaggatt ccgcatgtta
    21541 tttatggagc cagcaatcaa aaatttggtg gagcagacag cctttaccag attttgacag
    21601 atgagcgctt aaaccaccgc gtgcaagttg aacgaggcct gctagcagca gactgtgcta
    21661 acatcatgca aacctttttc cgccaagggc gagagcgcaa aaaaatagct aagcatttga
    21721 tcaaggaaca gtcagatccc tttgactaga gttttaagga gtttgttatc acatgcattt
    21781 ttggtgaagg gtagcctgtc aaaatactga gtgaaacgtc agaccattct tccaatggtt
    21841 gttagattca acatacgaag atagaatata caaaagggcg tttccaagta ctagaagcgc
    21901 tctttttcag acccaatcga gatgaaaaca atcgaaaaat aaaacacgtg atgactagat
    21961 gagttagtca ttcttaaaaa gatttactat ctaaaaacag atagtaatgg ctcaccttat
    22021 ttttgttttt agtaaactta tcaagctcag acttcgaagg ctcagagctg tcagttatct
    22081 gtggcgtaga ttgacactga cacagggatt aaaaacaagt gacttatagg catggcttga
    22141 gttatttaat cttttgtctt agctgatata ttttgctaaa gcattaaaaa agagctcatc
    22201 actgttgcta atgttacaag cattagatgt gctcaatctg aaaaggttat atctattgaa
    22261 gacggttaga ataataatcg ccttcaattg tgttagtata tcaatttctt gtaatgtttg
    22321 acaaagataa tcatcttaac tttgtgtttc atgtgtctaa acctagttcc tactagcaaa
    22381 tgaaatacta agagtctctg gtaagagtcc ataggtaaag cccgtataat tattccaata
    22441 ctgattgaaa aggttatgat aacctgtttg attcgtcgtt aaatcagtta ccatctgttg
    22501 ataatcatct tgatgagcaa attgtagaga cagtggctct tgtctattta acaactgatt
    22561 ttcaaggctt gcaaggatgg cgtcactgtc aaacgttgag atatagcttt gatgacgttt
    22621 agaataaagc aaagaatcat ctgtacaaga aggtatagtc caaacatttt caaaacgttc
    22681 tttagtatta aaagcaatgt ctttgcttgg ctgatgtgat aaggccatta gataatctgg
    22741 taggcataga aaactgtaat tgatagttcc ttgcttttga tgtgagagat ggttatcaaa
    22801 aacagggtca ccccaagtga catcaacgcc ataataagtg ttattaattt gaacagcatt
    22861 ccatgcatgt gcaaaagatt gctgaggttg ctgagatgta ccagttccac ggatataggc
    22921 gactggaatg ccagcttttt gacaaagaaa ctgaaaggct tgggcatagc cattacaaac
    22981 agataaatga tcaataaaaa cacttttaat gtcttgatta gaagcgacct gggcttgact
    23041 gcctgattga taggcttcaa aggctttttt attgtagtct gtgtctcgaa tgatgacctc
    23101 ataaaaatac ttgacctgct catagcgatc ctttgatggc gtgtttgcga cgatatcatt
    23161 accgattgct tgcaagtctt gataaacatt cttggcatct tttgggatag gaaaggtgac
    23221 aaagaccgtt tgatcagaaa actcaaatcg ataatcggca gatgtaatcc agtaaaattc
    23281 gggattatcc atcacaaagg cgtcaattgt tttaattaag ctttttttag aagccggcgt
    23341 caaactgatg atttcacgaa attgtgctag actatcgtat aaagtgaggt aattttcttg
    23401 ttcggttttg gataattgtt ggaaataata ccgttgtctt acttgtttga cgatttgttg
    23461 gcgctttttt ccggttaaag aaaaaacaga atcggtatta gaaggtttgc tagtgttgtg
    23521 acacgcagac ataccaactg tcataaggcc aattactgtt aagattttaa tcttttgttt
    23581 catcataact cccattctaa tctaataatc ttattataac atagagaata gctggaatgg
    23641 ggagagggaa agattttcaa aaagcaaaat cgtgtttgga aagggtcatg atttttctag
    23701 gtattcagtc catcttgtcc caaaatgaag ctatgctcac ttgaaagtga ttttacttag
    23761 ttggaaaact tgcaaactgt ccgtaatatg atataataat aggcggagca acacttgtgc
    23821 gtgaagtggg tcaggggagg aatccagcag ccctaagcga ttttcgggtg tgtgctcttt
    23881 ttttgttgac tttactaaag taatctcctc cttctatagt gtcatcagtt gttgaaaccg
    23941 attgatattt ttatttaggc taagaggtat aaaacaggac ataaaaagtt ttaaatgaaa
    24001 acaaacattt tgacaattat catattatca tgtgttttta gctatggaag tcaattagct
    24061 tatgcagatg aaaatttaaa agatttaaaa agaagtttaa ggtttgccta taatattacc
    24121 ccatgcgatt atgaaaatgt agaaattgca tttgttacta caaatagcat acatattaat
    24181 actaaacaaa aaagatcgga atgtattctt tatgttgatt ctattgtatc tttaggcatt
    24241 actgatcagt ttataaaagg ggataaggtc gatgtttttg gtctccctta taatttttcc
    24301 ccaccttatg tagataatat ttatggtggt attgtaaaac attcgaatca aggaaataaa
    24361 tcattacagt ttgtaggaat tttaaatcaa gatgggaaag aaacttattt gccctctgag
    24421 gctgttcgca taaaaaagaa acagtttact ttacaggaat ttgattttaa aataagaaaa
    24481 tttctaatgg aaaaatacaa tatctatgat tcggaatcgc gttatacatc ggggagcctt
    24541 ttccttgcta ctaaagatag taaacattat gaagttgatt tatttaataa ggatgataag
    24601 cttttaagtc gagacagttt ctttaaaagg tataaagata ataagatttt taatagtgaa
    24661 gaaattagtc attttgatat ctacttaaaa acgcactagt gctattctcc cccctttgct
    24721 ttttaagtat tcaaatgatt gccattttta gataatgaga gtaagtaatg ttaagaagat
    24781 agcatgagaa agtatttaca ggtgattggg gcttcaattg cctttgtagg tgtggcttta
    24841 tgcattgatc atatgcatga tggggttatt acccgtgttg aaatgataaa atccttaaaa
    24901 taagttatta cggtaaagcg gcctcagggc cttttttcat gatattttta ggaaatatga
    24961 aatcctattt tctcttaaaa aaccactatg atgagaatat gcttgcattg acacattttt
    25021 tatgtctgaa aaaacgaaaa ccttttcaaa aaacctagct ttttcacagg tgaaaaccac
    25081 taaaaaccat tgaaatatta gatagaaaag gttatcatac taatgaaact taaaatttta
    25141 agggagcgaa actcatgtca catattacat ttgattattc aaaagtcctc gagtcatttg
    25201 cgggacaaca tgaaattgat tttttacaag gccaagtcac agaagctgac aagttattgc
    25261 gtgaaggaac tggaccaggt tcagatttct tgggttggct tgatcttcca gaaaactatg
    25321 acaaagagga atttgcacgt atcctgactg ctgctgaaaa aattaagtca gacagcgaag
    25381 ttcttgtggt gatcggtatt ggtgggtcat accttggtgc caaagcagcg attgattttt
    25441 taaatcatca ttttgctaac ttacaaactg ccaaagagcg caaagcccca caaattcttt
    25501 acgctggaaa ctctatttca tctacttacc ttgccgattt agttgaatac gttcaagaca
    25561 aagagttctc agtaaacgtg atctctaaat caggtacaac cactgaacca gctattgcct
    25621 ttcgcgtgtt caaagaactt ttggttaaaa aatatggcca agaagaagct aacaaacgta
    25681 tctacgctac cacagacaaa gtgaaaggtg ctgttaaggt agaagctgac gctaacaact
    25741 gggaaacatt tgtggtgcca gataatgttg gtggtcgttt ctcagtcttg actgctgttg
    25801 gtttgcttcc aattgctgca tcaggtgcag atattactgc tcttatggaa ggggcaaatg
    25861 ctgctcgtaa agacctttct tcagacaaaa tctctgaaaa cattgcttac caatacgctg
    25921 ctgttcgtaa tgtgctttac cgtaaaggct acatcactga aatcttggct aactacgagc
    25981 catctcttca gtactttggc gaatggtgga aacaattagc tggtgaatca gaaggaaaag
    26041 accaaaaagg gatttaccca acttcagcta acttctcaac agaccttcac tcacttggtc
    26101 aatttatcca agaaggttac cgtaacctct ttgaaacagt tattcgtgtt gataaccctc
    26161 gtaaaaatgt tatcattcct gaattagcag aagacctaga tggtcttggt taccttcaag
    26221 gtaaagacgt tgattttgtt aataagaaag ccacagatgg tgtgcttctt gcccacacag
    26281 atggcggcgt gccaaacatg tttgtcactc ttccagctca agatgaattt actcttggtt
    26341 acactattta cttctttgag cttgccatcg ctgtttcagg ctacatgaat gctgtcaacc
    26401 catttgatca accaggtgtt gaagcttaca aacgtaacat gtttgcgctt cttggaaaac
    26461 caggttttga agcattatca gcagagctta atgctcgcct ctaatcaaca gatagtcaaa
    26521 aagacttctt ccttgtacaa gagcttaaaa gttagccaag caatctaaga attggggcgg
    26581 cacttccatc atcaagtgga tacaaggtta agtaaaagcg ataataaagt gcgcttccag
    26641 aacatgggag cgcactttat tatgccaaat tttagataag accttcaaaa aagggaagaa
    26701 gatcctacaa gaggagttga accgctataa cagttccagt tctgtttcta agcaaatagc
    26761 aatggctaaa aagagagctt atcaaggttg caagtgacaa ccttaaagac cccctagact
    26821 gtgaaagtat ctaggaggga ctgtcaaaaa attaagaagg aactctccaa agttcttcta
    26881 aacgtttttg gtagtggttc tggtgcaagg ctaagatggt tttgattaaa tcttcgcgct
    26941 gctgttggat acagtccaaa cttaaaccaa ccaagcgggt ctctttggga aaaacaccga
    27001 gttcttttaa gaaaggcaag agcttctgac tggtcacaac cagatctaca ggtttatcat
    27061 agggataaat attatcagat aagatattga cccgtgacag ttcaactttg taagaaggga
    27121 tagttgaggt gatgaaatta gctataacgt taccaacagt ttcttggctc tcaataacag
    27181 taatattgat tggagcaata gagctttcca agatctgctc aaggtataaa cacatcaagt
    27241 gtaagtgacc agaactaata ctgccttgac ggcctgtgtc ataaagccaa tctttgataa
    27301 cggtttcaag cttatctagt agtagcatgt tgccttgata ttgatcaaaa taataaccat
    27361 caaaggtaat taaagtttgt aaattgtaga gagttctttt gaaaaaagga attaagttag
    27421 ggatatgctc atgaatatcg gaatattttc caactagtgc ctgaagacga tggattagta
    27481 aatgataatc gggatctttg gtgattaaat ggtaaagttg ttgtcgctga tgacttgtcc
    27541 agtacccact caagagggag ttatcagtcg ttaaataaat taaaaagaga tagtcaaaat
    27601 catcagacga aaatgtgaca cgagttcgag gtgctagctc atccacggca atggttttga
    27661 tattgtcaaa aataggcaag gatttgagat gttcaaaaag agctaaatga ggcaaatgaa
    27721 caggatagcg atggcgcttc caagtcaaca tcaacagcac atcaaaaaac aagaagcgtc
    27781 tatctaaaaa ggcagaaggt tgtaagtttt tttgtgctgc aaagataaaa gcatgaatcg
    27841 tttcaatgtc tgcaggttgt atatcatata atataatgcc gtactcttta tgtaaaagag
    27901 caatcaaata ccgtatttta agttcatctc cgataacagt attgtctaca atatttaaac
    27961 caatgtcttg taaataatgt tttaatttat gaataagacg ataagctttt gactgggata
    28021 tcccttgttt tcgtgtataa acagcgattg atttgtgttt gggattatct agtaataaga
    28081 atgtcaacat ttttagagta tctgataagg caaaaatgtc ataaaaaaat gcttctcgct
    28141 tatcatttaa tacctcacaa taaatacgag atttaataag ctcaatacgt aagtaccctt
    28201 taaataaggc gttaaattgt cgaagatact gctttatttt taaagcagtc aaagttgttt
    28261 gagaacaagc tgctgccatc gtcagttctt tttctgtcaa caaaatagcc agtaggattt
    28321 tctggtcaat aatatcggat tccaaataat aatctaacaa tgtaattttt ctctccttaa
    28381 attaaattgt ataatcctat atattgtagc gaatctaccg taaaagtcaa ctaaaatcaa
    28441 taggattacc agtatagtca caataaagat catcaaaaag cagcaaactt catcaataga
    28501 ttgattgatg cgtgttttta gcccataatt gagagagcta agaacacgcg ggtgatatca
    28561 tatttttgct gttgactttt taaatttaaa aacctaacca gccggttaac tggtcaggtt
    28621 taaacaaggg agggcaccta agaagatagg tgcccaggag atttatgaaa agggaaaaca
    28681 aggggaaaac ctattctccc aacggtttag gtaaaccgct ttttaggatg ttttcattct
    28741 acgatagtaa ccttaaagtt ttcttaaatg attctttaga atgcctttat ttttaatctt
    28801 ttttgagaga gctagtttct tgtcagcctt gaaccttttt cctaatttat ggtatgataa
    28861 gaagatgatg aaaaaagaga ttctcaaaga actcttctag tctttacgaa ctatggatgt
    28921 agacttaaaa cgtcaaaatg atcaagcttt attagtggat gttgttagca atcaagctta
    28981 tcagcgggcc aatacgattg ccaaatcaaa cgatttatga tattgctgtt taggaggttt
    29041 atcttagatg acacggttat taaaacgata tcctattact attttccttt tagggttaac
    29101 aggcttaatt tttatagcaa tgcaagtggt atatggacat ttagcaactg gtgctcaagc
    29161 tatttatcaa gttggaggta tgtttggatt actagtaaaa gcaatgccag accagttgtg
    29221 gcgattggtg actccgatat ttattcatat cggctttggt catttttttg tcaatggatt
    29281 aacactatat tttgttggtc aaatcgtcga agacctctgg ggctcacgcc gttttttatt
    29341 actttatgtt ttatcaggtg ttatgggcaa tgcctttact ttttggttga ctcctgaaac
    29401 agtagctgca ggagcatcga cgtcgttatt tggacttttt gctgctattg tagtattgag
    29461 ttttttgggt aagaaccaag cgttgaaaga tttgggcaag tcataccaaa cgttaattgt
    29521 agtcaattta ctgatgaatc tttttatgcc aaacgtgagt atggcaggcc atattggcgg
    29581 tgtcgcgggt ggtgcgttac tgagtatagt ttttccaact aagatgagag tgataacagt
    29641 gaagaaaact aagcgaatgt tggctttagt gagctatggt attattttgg ttggtgtgtt
    29701 agtgcttggg tttttataaa aataagtgag tggttagcac tgttacttct cagatgacta
    29761 gtaggatgaa atgacttaaa aaccataaaa ataaggaggg attttccctc cttattttta
    29821 tggttttgtc ttctctagtg ctttgcccag ttggatgatg taggctttca agtcatcttt
    29881 gacttgaggg tgtttcaggg cataatccaa agaagttttc ataaacccaa atttatcgcc
    29941 aacatcatag cgtttccctt taaactcacg agcaaagaca cgctgtgtct tattgagggt
    30001 atcaatagca tcagtcagtt gaacttcatt gcctgcacca ggttcttgtt tttctaaaat
    30061 actaaaaatt tctggtgtga gcaagtaacg tccaataatt gccaaatcac taggtgcatc
    30121 ttgaggttgt ggtttttcaa caaaagtatc cacactatag agtcctttta ctgcttttgc
    30181 ttgaggagca atgataccgt agttagagac atcctcgtga ggaaccctca tgacggcaat
    30241 agttgcagca tgagtttctt catagtcatc gatcaattgt ttggttaatg gttttacatt
    30301 tggatttgta atatccatca gatcatcacc tagcatgaca acaaaaggtt cattgccaac
    30361 aaaggtcttt gcttgaagaa ctgcgtctcc taatcctctt ggatgactct gtcgaataaa
    30421 gtgaagatta atagaagtgg tctcgtctac taactttaga agttcgattt ttcctttagc
    30481 ctgtaaatta tattctaatt caaaattaga atcaaaatga tcttctatgg agcgtttgga
    30541 ttttccagta acgataagaa tttcttcgat acctgatttt agagcttctt caacgataaa
    30601 ttgaatagtt ggtttatcaa caataggtag catctccttg gcaagggcct tggttgcagg
    30661 taaaaaacgt gtgcctaaac ctgctgcggg aataatagct tttctgactt tggtcatcag
    30721 cacctcctct tattttagtg acgaatggct taatgccatt cattttcaga acgaaattca
    30781 tttgacatca tgccgaggat gctttctttg atatcagcgc cctcgtagat ggacttataa
    30841 atagctgttg taattggcat gtaaactccg aggtcttggg caatttcata ggctacctta
    30901 gttgttgcga tgccttcgat aaccataccc atgttgcgtt caatatcttc taatttttca
    30961 ccacgtccaa gggcagctcc agcccgccag ttacgtgaat ggacagaagt acctgttaca
    31021 attagatcac caacaccaga taacccactg taggttaacg ggtcagcacc aagcttgacg
    31081 cctagacggg tgatttcagc taacccacga gtaattaccg ctgctttggc attatctcca
    31141 tacccaagtc catggagagc tcctgctcca acagcaataa tgtttttgag ggcaccagct
    31201 gtttcaactc cgatgacgtc ggtattggta taaagtcgga agtagtggtt actaaagagg
    31261 gactgaacat actttgcagc ttcaatatct tttgaggctg ccgtgatgag agtaatatcg
    31321 cgaacgatag tttcttcagc atgactagga cctgatacaa cgaccacttc actacgaaaa
    31381 tgagctggaa tttcttcttc taggatagtt gataaacgtt cgtgggtctc tggttctaga
    31441 ccttttgagg catgcatgac cactacttta tgatctaaaa tggcggcaac ttgtctagca
    31501 actaatcgtg ttactttagt tggcacaaca aaaagcaccg catcaacatc tgatagggct
    31561 tgacctaaat caagagttgc cgtaatgttt ttgtctaaca caatgtcttt gaagtagtgt
    31621 ctattggtat gcttggtatt tatctcttca atttgatcag gaatatttcc ccataaacgg
    31681 acgtcatggc cattgtcatt aagaacctga gaaagggcag ttccccaaga accaggtcct
    31741 aaaatagcta ctttttgttt tgtcattcta aattctcctt caagagctag tcactctatt
    31801 ataacataac accttgatta gctctattag aaaaggtata tggtcttggc taataaggcg
    31861 ttcccaagag agctagctat attaataatg ttgtttaata agcttcatca ggtgagctgt
    31921 tgtcatggct ttgccctgtt ctttttagtt atttaagttc ggaaacttat ttttaaaaat
    31981 aaagatattt taattgacaa tagttatcta gagaactaaa atacttatca tagaaactat
    32041 taaagaaaat aaggagggaa gagatgtcac aagtgatagg tgatttacgt gaattgatac
    32101 atcaaatcga acaaattagt gatgagattg caaaaaaata tgatgtagaa catctagcag
    32161 gtcctcaagg ttatgttctt gtttttttag ctaaacacca aaatcaagaa atatttgtca
    32221 aagatattga aaaacaactt cgtatctcaa agtcagttgc tagtcattta gtgaaacgta
    32281 tggtcaaaaa tgggtttatc aatgtgatgc cttcccaagt ggataagcgt tataagcaag
    32341 tagtgttagc gcaggttggt agagataaat tgcctttgtt gcgggagtgt cgtaaggata
    32401 tcgagcacta ttttttaaaa gaaattacaa aagaagagtt gctgacagcg aaaaaagtaa
    32461 ttgaacagct caagcaaaat atgctaactt ataaaggaga caacgatgct taaagaagca
    32521 atcttacgtt ataaatggta tgctttaggc tcatttttta tggttattgg ggttgttgca
    32581 agtagtctct tgcaaccaca ttatcttaaa tctgtgctaa gcgctgttat tcaaaataat
    32641 caagagaaaa tttatgaggt tgggaaacca ttacttatta ttgccctttt agggttaatg
    32701 tctggagcga ttaatacggt tttagctgct aaaatagctc aaggtgtatc tgctgatatg
    32761 agggagaaga cctttcgaaa aatccaagac ttttcatatg ccaatattga agcttttaat
    32821 gctggtaatc ttgtggttag gctaactaat gatatcaatc aaatccaaag tttagtcatg
    32881 atgatgtttc aaattctctt tcgtttgccg atccttttta ttggcgcgtt tattatggca
    32941 gttcagacat tccctcaatt atggtgggtc attgttgtaa tggttatctt aattgccctc
    33001 atcatgggtt tggtgatgcg tcaaatgggt cctcgttttg gtaaatttca acggttaatg
    33061 gataagatta atcgcatcgc taaggaaaat ctccgtggcg ttcgcgtggt taaatcattt
    33121 gtacaagaac aacaacaata cactaaattt aaagaaacgt ccaatgatct tttggcgtta
    33181 aatttatcta ttggttatgg tttttcacta atgcagccgg ctttaatgtt ggtgtcttat
    33241 ttggcagttt atgtttctat aaatgttgtt tcgaccatgg tcgaaacaga tccaacagtg
    33301 attgggaata ttgcctcttt catgacttat atgatgcaaa ttatgttttc aattattgtg
    33361 gttggttcca tggggatgca agttagtcgt gcttttgttt ctatggctag aattaggcaa
    33421 atattgtcta cagaacctgc catgacattt gaaaatgaaa aggaagaaac catctcagga
    33481 agcattgtat ttgacgatgt tagttttaca tatcctaatg atgatgagcc aaccttgaag
    33541 cacatttctt ttgctattga atctgggcaa atggtcggca tcgttggtgc aacaggatct
    33601 gggaaatcaa cgcttgcaca gctcatccct cgcttatttg atcctcaaga tggccaaatt
    33661 ttgttaggag gaaagccgat taaaacccta agtcaaacaa ccctgcgcca atcggtttcc
    33721 atcgtgttgc aaaaggctat tctcttttca ggaacgatag ctgataacct tcgccaaggc
    33781 tcagcaaaag ctgatattga tgctatgcaa aaagccgctc aaatcgcgca agcaaaagaa
    33841 tttattgatc gtatggatag ccgttatgag agccaagttg aagagcgagg tagtaacttg
    33901 tctggcggac aaaagcaacg tctgtctatt gcacgtggtg tcattaatca tcccaaaatt
    33961 cttatattag acgattccac ttcagctctt gatgcaaaat ctgaaaaacg cgttcaagaa
    34021 gccttaagtc ataaattaga aggtacaact acagttattg ttgctcaaaa aatttcatcg
    34081 gtagttaagg cagataagat cttagtcctt gaccaaggac agttaattgg agaaggaaca
    34141 cacgcagagt tggtggctaa taatgcgatt tatcgtgaaa tttatgagac acaaaaagga
    34201 agggaggagt agtgatgaaa acagcacgtt ttttctggtt ttattttaaa cgctatcgtt
    34261 tctcatttac tgtcattgct gttgccgtta tcttagcaac ttatttacaa gtaaaagctc
    34321 ctgtcttctt aggagagtcc ttgactgagt tgggaaaaat cggtcaggct tattacgttg
    34381 ctaagatgag tggtcagaca cattttagcc ctgatttatc agcttttaat gccgtgatgt
    34441 ttaagctttt gatgacttat ttctttactg ttttagctaa tctaatatat agtttcttac
    34501 ttacacgtgt tgtctcacat tcgactaacc gcatgcgcaa gggcttgttt ggtaaattag
    34561 aacgtttaac cgtcgccttt tttgaccgcc ataaagatgg ggagattctt tctcgtttca
    34621 cgagtgattt ggataatatt caaaactcgc tgaaccaatc cttggttcaa gtggtgacta
    34681 atattgccct ttacatcggc ctggtctgga tgatgtttag gcaagatagc cgtttagctt
    34741 tgttaaccat cgcatcaacc ccagttgctc tcattttttt agtgattaac atccgtttgg
    34801 caagaaaata caccaatatt caacagcaag aagtcagtgc tttaaatgct tttatggatg
    34861 aaaccatttc aggacaaaag gctattattg tacaaggtgt ccaagaagat acggtgacag
    34921 cctttttaaa acataacgaa agggttcgac aagccacctt caaacgccgt ctgttctcag
    34981 gacaattatt tccagtcatg aatggaatga gccttattaa cacggctatc gtgatttttg
    35041 tcggttcaac aattgtcctc agtgacaaat ctatgccagc agcggcagcg cttggtttag
    35101 tggttacttt tgtacaatat tcccagcaat attaccaacc catgatgcaa atcgcgtcta
    35161 gttggggaga attgcagctg gcctttaccg gtgctcatcg tattcaagaa atgtttgatg
    35221 aaaccgaaga agttcgtcca caaaatgcac cagcgttcac cagcttaaaa gaagcagtgg
    35281 ccatcaacca cgttgatttt ggttaccttc ctgggcaaaa agtcttatcg gatgtgtcaa
    35341 tcgttgcacc caagggcaaa atgattgccg tggttggacc gacaggttct ggaaagacca
    35401 ctattatgaa cttgattaac cgtttctacg atgtggatgc aggttcgatt acctttgatg
    35461 gccgtgatat tcgtgactac gatttggata gtcttcgtca aaaggtaggg attgtgttgc
    35521 aagagtcagt tcttttttca ggaaccatta cggataatat tcgttttggt gatcagacca
    35581 ttagtcaaga catggttgaa actgctgcgc gtgcgaccca tattcatgac tttatcatgt
    35641 ccttaccaaa agggtacaat acctatgtct cagatgatga caatgtcttt tcaacaggtc
    35701 aaaagcagtt gatttctatt gctaggacgc tactgactga ccctgaagtg ttaattttgg
    35761 atgaggccac ttcaaatgtt gatacggtta ccgaaagtaa aattcaacgg gccatggaag
    35821 ctatcgtggc aggtcgaacc agctttgtca ttgctcaccg cctcaaaacc attttaaatg
    35881 ccgatcacat tattgtgttg aaagatggca aggtcattga gcaaggaaat catcatgagc
    35941 tattgcatca aaaaggcttt tatgccgaat tatatcataa tcaatttgtc tttgaataga
    36001 tggcatcagc tccgcgtctt agcggagttt tttggtgaac aataaagtag tcaagctttc
    36061 tttcctgata tggtataata gcaagcaaga gaaaaaacaa ttagaaagta gccacaatga
    36121 ttgatttaca agagattctc gctaacatga atcccaatca aaagataaat tatgacaggg
    36181 tcatgcaaca gatggccaag gtttgggaga aggaatccgt gcgtcccagt attttaatgc
    36241 atgtctgctg cgccccatgc tccacttaca ccctagaata cctgacgcag tttgctgaca
    36301 ttacggttta ctttgccaat tctaatattc accctaagga cgaataccat cgcagagcct
    36361 atgtgacaca acagtttgtc tccgagttca acgctaaaac aggcaacacc gtgcagtttc
    36421 tcgaagcgga ctatgtcccc aatgagtacg ttcgacaagt gcgaggttta gaagaagaac
    36481 cagaaggtgg ggaccgttgc cgtgtctgtt ttgattaccg actagacaag accgctcaaa
    36541 aagcagtgga actaggtttt gactactttg ccagtgccct aaccatcagt cctcataaaa
    36601 attcgcaaac cattaatgat gtgggcatcg atgtgcaaaa ggtttacacc accaaatacc
    36661 tgccaagtga tttcaagaaa aacaacggtt atcgcagatc cgttgaaatg tgtgaggagt
    36721 atgatattta ccgtcaatgc tattgtggct gtgtctatgc tgccaaaatg caaggtattg
    36781 acttggttca agtgaaaaaa gatgccaaag cttttatggc agacaaggat ttggataatg
    36841 atttcaccca catccgcttt agttatcgtg gggatgagat gtgatggcat gattaaaagt
    36901 ggtccgttta aagttgaccg cttttttgct attcttttac gaatagtcta taataagagg
    36961 atatgattga cttgaaagga tatacctatc ataatgacaa aaattcgtgg tttcgagctt
    37021 gtttcaagct ttactaatcc tgatttacta ccaaaacgtg agacgactca tgcagctggt
    37081 tatgacctgt ctgttgctga ggctgtaacc attgccccag gggagattaa gttggtacca
    37141 acaggggtta aggcctatat gcaagatggt gaggtgcttt acctctatga tcgttcgtca
    37201 aatccacgaa aaaaagggat tatcctgatt aattcagtag gtgtgattga tgcagattat
    37261 tatggcaatg aggctaatga aggacatatt tttgcacaaa tgcaaaacat tacagatcac
    37321 cctgtgacat tagctgtggg tgagaggatc gttcagggtg tttttatgcc ttttttaatt
    37381 gctgatggtg accaagccag aggtgaacga acaggtggtt ttggttcgac agggcagtaa
    37441 agcgatttaa caaaaatgct tatgacagca gacctattct ttaagagtgg gtttgtcttg
    37501 tctaggggag ggagattact atggcaaaga aaaaagcaac ctttatctgt caggagtgtg
    37561 gctaccagtc gccaaagtat ttagggcgct gtccaaattg ctcggcctgg tcttcttttg
    37621 tggaagaagt agaggtcaaa gaagtcaaaa atgcccgtgt tagtctagct ggagaaaagt
    37681 ccagaccggt taaactaaaa gatgtggata atattagtta tcacagaaca cagactgaca
    37741 tgtctgaatt taatagagtt cttggagggg gtgtggttcc tggaagcttg attttaattg
    37801 gtggtgatcc aggtattgga aaatctacct tactcttgca ggtatccacg cagctcgcta
    37861 ataagggaac ggttctctat gtgtctgggg aagaatcagc agagcagatt aaactgcgga
    37921 gtgagcgtct gggtgatatt gacaatgaat tttacctcta tgccgaaacc aatatgcaag
    37981 ctattcgcac agaaattgaa aatattaaac cagatttttt aattattgac tccattcaga
    38041 ctatcatgag ccctgatatt acaggtgttc aaggatcagt cagtcaggtg agagaagtca
    38101 ctgcagaatt gatgcagctt gcaaagacga acaacattgc aacctttatt gtgggtcatg
    38161 tcaccaagga aggaaccttg gctgggcctc gtatgttaga acatatggtg gataccgttc
    38221 tctactttga aggggaaagg catcacacct ttcgcattct tcgggctgtg aaaaaccgct
    38281 ttggctccac taacgagatt ggcatctttg aaatgcagtc tggcggcttg gtagaggtct
    38341 taaatcctag tcaagtcttt ttagaggaac gcttagatgg ggcaacagga tcggctgtcg
    38401 ttgtaacgat ggaaggaagt cgtcctatct tagcagaggt gcaatcttta gtgacaccaa
    38461 ccgtttttgg caatgccaga cgaaccacta cgggacttga tttcaatcgc gtaagcctaa
    38521 taatggcagt tttagaaaag cgttgtggtt tactcttaca aaatcaagat gcctacctca
    38581 agtcggctgg tggtgtcaaa ctagacgaac ctgccattga tttggcagtc gctgtggcta
    38641 tcgcatccag ttataaggaa aaaccaacca gccctcaaga agctttctta ggcgagatcg
    38701 ggttaacagg tgagattcgg cgagtgaccc gtattgagca acggattaat gaagcagcaa
    38761 agcttggatt taccaaggtc tatgctccta aaaatgcttt gcaaggcatt gatatccctc
    38821 aaggtattga ggttgttgga gtgactacgg ttggtcaggt tttaaaggca gtttttagct
    38881 agaggatcag aaactaagag caaatgagga ggaaatttgt caagaaagta tcccaatcat
    38941 ttgttttttt aacttttcga acgataccgg ccgtctaaga ggttaatcca gctattttcc
    39001 ataaaagatg ttaagataag acaaactaac agcaaaaata gctctgctgt ttctcaaaag
    39061 gagtttattg atgtcttatt ttgaacattt tatggctgcc aatcaggctt atgtggcctt
    39121 gcatgggaca gctcatttgc ccttaaaacc caagactaaa gtagcgattg tgacttgtat
    39181 ggattcacgg ctacatgtgg cccaagctct ggggctggct ctaggagatg ctcatatttt
    39241 aaggaatgct ggtggacgtg tcaccgaaga catgattcgg tcgctggtta tttctcagca
    39301 gcaaatggga acgagagaga ttgtggttct ccaccataca gattgtggcg cgcagacttt
    39361 tactaatgaa ggctttgcca agcatattca tgagcactta ggtgtggatg tttcagggca
    39421 agatttcctt cccttccaag atgtggaaga cagtgtccgc gaggatatga ctaagataag
    39481 agcctcctct cttatctctg atgatgtcgt tattaacggt gccgtctacg atgtggatac
    39541 tggaaagatg acacaagtaa tggaatagtt agtagccaag ttgtagagct gaattcagct
    39601 cttttttatt tttaaaaatt attgaaaata ttagacaaag aaatagggaa gcgttataat
    39661 aattgtatca agttattcat acaaacaagg agagtaagat ggtcgacaat agaatgagat
    39721 ttacgattga tcaaaacatg caatttccac tagttgagat tgatctggaa catgggggat
    39781 cagtttactt acaacaagga agtatggttt atcatactga gaatgtaacc ttgaatacca
    39841 aattgaatgg taagggatct ggtttaggaa aattagttgg agccatcggc cgttccatgg
    39901 tttctggtga atcaatgttc attacacaag ctatgtcaaa tggagatggt aaattagcat
    39961 tagcacccaa tacaccagga cagattgttg ctttagaact aggtgaaaaa caatatcgtc
    40021 taaatgatgg tgcctttcta gccctagatg gttcagcaca gtacaaaatg gaacgtcaaa
    40081 atattggaaa agcacttttt ggtggtcaag gcggactttt tgtcatgaca actgaaggcc
    40141 ttggtacctt acttgctaac tcgtttggat ctatcaagaa aatcacactt gatggtggca
    40201 caatgactat tgataatgcc catgttgtag catggagcag agaacttgat tatgatattc
    40261 atttagaaaa tggctttatg cagtcaattg gtacaggtga aggagttgtt aataccttta
    40321 gaggtcatgg tgagatttat atccaaagtc ttaaccttga gcaatttgct gggactctta
    40381 aacgttatct accaactagt tcaaattagt caaaataaca taaaatcagc tttttagggc
    40441 tgattttttt cgcctaagca agtaaaatat gctataataa gaaagatttt agaagaagtc
    40501 tgaaaaggtc ttggcaagct caaatcatca tttgttgctt gtttttcgtg ccacaggttt
    40561 ctgagtgata tatgtaacag gagaagaagc atgtctaaac caattcgtgt gcgttatgca
    40621 ccaagtccaa cagggctttt acatatcggg aatgcccgca cagccctatt taattacctt
    40681 tatgcccgtc gtcacggagg tacttttatc attcgtattg aagatactga ccgtaaacgt
    40741 catgttgaag atggtgaacg ttctcaactt gaaaacctaa aatggttagg aatggattgg
    40801 gatgaaagcc cagaaacgca tgaaaattac cgccagtctg aacgtctagc actttatcaa
    40861 caatatattg atcaattgtt agctgaagga aaagcctata agtcttacgt gactgaggaa
    40921 gaattggcag cagagcgtga acgccaagaa gcagctggcg aaacgcctcg ctatatcaat
    40981 gaatttattg gtatgtcagc tgacgaaaaa gctaagtaca ttgctgagcg tgaagcagca
    41041 ggtatcgttc caacagtccg tcttgctgtt aatgagtccg gtatttacaa atggactgac
    41101 atggttaaag gcgacattga gtttgaaggt ggcaatatcg gtggtgactg ggttattcag
    41161 aaaaaagatg gctacccaac ttataacttt gccgttgttg ttgatgatca tgatatgcaa
    41221 atttctcacg ttatccgtgg cgatgaccat attgccaata cgccaaaaca attgatggtc
    41281 tatgaagctc ttggctggga agcgccagag tttggtcata tgactcttat catcaattct
    41341 gaaacgggta aaaaattatc aaaacgcgac accaataccc tccaattcat tgaagattac
    41401 cgcaaaaaag gttatatgcc tgaagctgtc tttaacttca tcgcccttct tggctggaat
    41461 cctggcggag aagaggaaat cttctctcgt gagcaactga ttgccctttt tgatgaaaat
    41521 cgccttagca agtcgccagc tgcctttgac cagaagaaaa tggattggat gagcaatgag
    41581 tatcttaaac atgcggattt tgaaacagtt tatgccctct gcaaaccatt ccttgaagag
    41641 gcaggccgtt tgacagaaaa agctgagaag ctagtagaat tatacaaacc tcaattaaaa
    41701 tctgcagatg agattattcc attgactgac cttttctttt ctgatttccc tgaattaaca
    41761 gaagccgaaa aagaagtgat ggcaggtgaa acagtttcga cagtcttgca agctttcaag
    41821 gctaagttgg aagctatgtc agatgaagac ttcaaaccag aaaatatttt cccacaaatt
    41881 aaggctgttc aaaaagaaac aggaatcaaa gggaaaaacc tctttatgcc tattcgtatt
    41941 gcagtatctg gtgaaatgca tggcccagaa ttaccaaata cgatttattt attgggacgt
    42001 gataaatcca ttgagcacat caaaaacatg ctataaggct gtatcgttca cctttatttt
    42061 taaacgcttt aaggagttaa aaagtcacga caacgaaaga ttgaagatta agttcttcag
    42121 tcttttttat cgttatctga gcttgctacc ttggtaaagt aaaaaatagt atagtttatt
    42181 tctattttgg agattggatt tgaaagagag gtggtgagat gcttacgtga taatgacagc
    42241 aaacggtgag gttttgatta gtgtgattta aagaaatggt ttttatgaat caattagtgt
    42301 acaatatttt tttggtatat gctgaaagag actagtttag tattcactta gctaatcaat
    42361 tgtaatcaaa taatattgta atcattgtca taaaatatgc taaaataata aagttggaaa
    42421 ggagaaaaaa atggctaata gcgaatatat gtttttatta ttatcaatta ttgtctatta
    42481 tatgacaaaa atttatattt tttcctttct atctgatatc acattaccag tttggaaaca
    42541 actaacgatt ttggctttag ccctattttt caatcagttc ccgtatttgt cgccattgct
    42601 aattgatcct ctattatttt tagttgtttt aaggcaagaa accaagcaat tattttcttt
    42661 gaaagctctt tttttggctg ttgcacctag tgttttggtg gatttgctat ctcggtttat
    42721 gggtacaatc gttatcccct atcttttttt gtcgagtggt atttatctgg gtcatattat
    42781 ctttgacttg cttgcttatc tgctgatttt tccaagtttt gctattatta attatatgat
    42841 tggaaaagat tacaagatga tatgccaatc cggatattcg aaacgatcgc ataattttta
    42901 tcaaacattg ctgatttttg ttttggttta ttatgtggac atttttgtca ttttaggatt
    42961 tacggacccc tttttacatt ttcatcattc tctttttgtt cccacacctt ataagttatt
    43021 gtttttgatg tttatacttc ttttagttta tcttctatct tattttaatc atagttctaa
    43081 agaatacctt aaaaatgagt tgagaagaga acaacaagct tatatgacta acttagagac
    43141 ttatgggaaa catcttgaga aactctatcg agatgtaaga gcttttcaaa gtgattacct
    43201 gagccgtata gagcgtttag gtcaagccat taagagtgaa tccattactc agattcaaga
    43261 tatttatgcc caaacggttc atgaagctaa cgactactgg gatgataaac actataatat
    43321 ctcgaagctt aggaaaatta atatctcatc gattaagagc ttattgtcag ctaaaattat
    43381 cagtgcggaa aaatcaggta ttgatttgaa tgtggaagtg ccagataata taaaagagac
    43441 ttacattcct gagttggact tactattgtt gatgtctatt ttttgtgata acgccattga
    43501 ggcagctctt gaagcacagc aacctcatat gtcaattgct tactttttgt tagatgacta
    43561 tcagatgttt gttgtgacaa atacgactaa aaaaaaggta gacattaaca agatctttga
    43621 agaaggctat tcttcaaaag gttcagaacg tggtatcggc ctttctaatg cgcagcgtat
    43681 tctcaaaaag tatccttatt tatccttgcg gactaaaagt tttgataagg aatttagcca
    43741 aaccttgacc atgccaaagg aggaggtgga tagatgatgg ttatatacag tatggcttta
    43801 ttctatgcta ccatctttat taacagctgg gtcatttttg caaaggtttc tgctattaaa
    43861 ctaagctgga aacggtttag cattataggc attagttttg taattgctaa tatgatattt
    43921 gacaaagtca ttttgattga ccaactgttc tttattattg ttagtttgtt aagtgctccg
    43981 aaaaagaaat tatttgagca tatgtttaat ggtttcttta ctatcttgat tgtcgaatta
    44041 ctgtttcgcg tcatcggatc tttcttttta ccagctgtct taggatttag cattggtcaa
    44101 attaataata accttaagct tttagagtta tgttatcttt ttgtattacc aatattttat
    44161 ctgtttagct acattttcag tattgactta agcttaataa ggtttatcag tgaagataag
    44221 atgaaaaagt gggtattttg gatgaatact gccatgtttt cttactactt tttcgcccat
    44281 tttttggtaa ctgtgcaaag cggattt
//
LOCUS       DAUNLR010000010        42529 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUNLR010000010 DAUNLR010000000
VERSION     DAUNLR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42529
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.010"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(180..2195)
                     /gene="recG"
                     /locus_tag="VLL59_000525"
     CDS             complement(180..2195)
                     /gene="recG"
                     /locus_tag="VLL59_000525"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HER6508672.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENRSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     HKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD"
     gene            complement(2570..4024)
                     /locus_tag="VLL59_000526"
     CDS             complement(2570..4024)
                     /locus_tag="VLL59_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508673.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVSTC
                     QIASGQFIVLCGPSGSGKSTFLKFLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQDLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(3961..4641)
                     /locus_tag="VLL59_000527"
     CDS             complement(3961..4641)
                     /locus_tag="VLL59_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HER6508674.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITA
                     IIIITILQ"
     gene            complement(4638..5231)
                     /locus_tag="VLL59_000528"
     CDS             complement(4638..5231)
                     /locus_tag="VLL59_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HER6508675.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            complement(5228..6898)
                     /locus_tag="VLL59_000529"
     CDS             complement(5228..6898)
                     /locus_tag="VLL59_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508676.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAALMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            complement(6891..8654)
                     /locus_tag="VLL59_000530"
     CDS             complement(6891..8654)
                     /locus_tag="VLL59_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HER6508677.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDLQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLSTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(8651..9487)
                     /locus_tag="VLL59_000531"
     CDS             complement(8651..9487)
                     /locus_tag="VLL59_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508678.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPLVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            complement(9484..10506)
                     /locus_tag="VLL59_000532"
     CDS             complement(9484..10506)
                     /locus_tag="VLL59_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HER6508679.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYEAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISSVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(10508..11392)
                     /gene="isdE"
                     /locus_tag="VLL59_000533"
     CDS             complement(10508..11392)
                     /gene="isdE"
                     /locus_tag="VLL59_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HER6508680.1"
                     /translation="MIKRCKGIGLALLAFFLVACVNQHPKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHS"
     gene            complement(11376..12251)
                     /locus_tag="VLL59_000534"
     CDS             complement(11376..12251)
                     /locus_tag="VLL59_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HER6508681.1"
                     /translation="MTKVVIKQLLQVILVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDNQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            complement(12448..16275)
                     /gene="shr"
                     /locus_tag="VLL59_000535"
     CDS             complement(12448..16275)
                     /gene="shr"
                     /locus_tag="VLL59_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HER6508682.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKPVPQN
                     KGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLTEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKSSNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVEKGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVMSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(16765..18294)
                     /locus_tag="VLL59_000536"
     CDS             complement(16765..18294)
                     /locus_tag="VLL59_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HER6508683.1"
                     /translation="MDKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNNNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLPKQLPEARTPI
                     QSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKS
                     TGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAF
                     DLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFT
                     DTTGSGKRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLG
                     YQASSYAWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAP
                     GQAGADGTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSK
                     N"
     gene            complement(18381..19481)
                     /locus_tag="VLL59_000537"
     CDS             complement(18381..19481)
                     /locus_tag="VLL59_000537"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HER6508684.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(19478..19834)
                     /locus_tag="VLL59_000538"
     CDS             complement(19478..19834)
                     /locus_tag="VLL59_000538"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HER6508685.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(19950..22469)
                     /gene="secA"
                     /locus_tag="VLL59_000539"
     CDS             complement(19950..22469)
                     /gene="secA"
                     /locus_tag="VLL59_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HER6508686.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
     gene            complement(22603..23556)
                     /gene="manA"
                     /locus_tag="VLL59_000540"
     CDS             complement(22603..23556)
                     /gene="manA"
                     /locus_tag="VLL59_000540"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HER6508687.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
     gene            complement(23651..24535)
                     /locus_tag="VLL59_000541"
     CDS             complement(23651..24535)
                     /locus_tag="VLL59_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HER6508688.1"
                     /translation="MGNLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIART
                     IAYFKAFEADLAGIAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLRQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            complement(24799..27768)
                     /locus_tag="VLL59_000542"
     CDS             complement(24799..27768)
                     /locus_tag="VLL59_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HER6508689.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKEKVPEKVKEILAKAQQADKQAQELTKMKIPEK
                     IPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLFW
                     KELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVD
                     EYVYKYNLDGLDVDVEHDSIPKVNGKANDENLKRSIDVFEEIGKLIGPKGVDKSRLFI
                     MDSTYMADKNPLIERGAPYINLLLVQIYGSQGEKGVFQNDTKLVTDTPEERWQGYSKY
                     IRPEQYMIGFSFYEERAGSGNLWYDINSRKDDDKANGINTDITGTRAERYARWQPKTG
                     GVKGGIFSYAIDRDGVAHQPKQIAEKDKQNVKNNQPQIPEITDNIFHSDYSVSKALKT
                     VMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNK
                     FKKLAQLDLIGLSRITKLDQSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLK
                     VSGLTGLKELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLS
                     TVSNHVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVANEKVDLQSQLLFGTVTNQGT
                     LINSEADYKAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATD
                     KEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIKSENDENAKKVFNGI
                     MEYNPISTQNRASIIFEIKDPSLAKYWRLFNDSSKDKKDYIKEAKLEVFTGQLNAEAD
                     VKTSLEKSDDWQTVSTYSGQEQVFSHALDNISAKYWRVTVDTKGGNYSWPSLPELQIL
                     GYPLPNADTIMETVTTAKELSQQKDKFSQKMLDELKIKEMALETSLNSKIFDVTAINA
                     NAGVLKDCIEKRQLLKK"
     gene            complement(28000..29883)
                     /locus_tag="VLL59_000543"
     CDS             complement(28000..29883)
                     /locus_tag="VLL59_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HER6508690.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWIVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFGIA
                     YTWGYQDREPLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLSAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAQAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            30125..31564
                     /locus_tag="VLL59_000544"
     CDS             30125..31564
                     /locus_tag="VLL59_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HER6508691.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            31569..32534
                     /locus_tag="VLL59_000545"
     CDS             31569..32534
                     /locus_tag="VLL59_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HER6508692.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(32675..33127)
                     /gene="nusB"
                     /locus_tag="VLL59_000546"
     CDS             complement(32675..33127)
                     /gene="nusB"
                     /locus_tag="VLL59_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HER6508693.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(33120..33509)
                     /locus_tag="VLL59_000547"
     CDS             complement(33120..33509)
                     /locus_tag="VLL59_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HER6508694.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            complement(33555..34112)
                     /gene="efp"
                     /locus_tag="VLL59_000548"
     CDS             complement(33555..34112)
                     /gene="efp"
                     /locus_tag="VLL59_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HER6508695.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            complement(34208..34669)
                     /locus_tag="VLL59_000549"
     CDS             complement(34208..34669)
                     /locus_tag="VLL59_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HER6508696.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            complement(34704..35777)
                     /locus_tag="VLL59_000550"
     CDS             complement(34704..35777)
                     /locus_tag="VLL59_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HER6508697.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRFIKDTSEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSRFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            complement(35893..38721)
                     /gene="uvrA"
                     /locus_tag="VLL59_000551"
     CDS             complement(35893..38721)
                     /gene="uvrA"
                     /locus_tag="VLL59_000551"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HER6508698.1"
                     /translation="MQNKIIIHGAKAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEITASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QHLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            38924..39868
                     /locus_tag="VLL59_000552"
     CDS             38924..39868
                     /locus_tag="VLL59_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HER6508699.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            40000..40656
                     /locus_tag="VLL59_000553"
     CDS             40000..40656
                     /locus_tag="VLL59_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HER6508700.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPLLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(40789..41028)
                     /locus_tag="VLL59_000554"
     CDS             complement(40789..41028)
                     /locus_tag="VLL59_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HER6508701.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(41193..41684)
                     /locus_tag="VLL59_000555"
     CDS             complement(41193..41684)
                     /locus_tag="VLL59_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HER6508702.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            complement(41706..41996)
                     /locus_tag="VLL59_000556"
     CDS             complement(41706..41996)
                     /locus_tag="VLL59_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HER6508703.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            complement(42169..42462)
                     /locus_tag="VLL59_000557"
     CDS             complement(42169..42462)
                     /locus_tag="VLL59_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508704.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
BASE COUNT        12876 a         9089 c         7475 g        13089 t
ORIGIN      
        1 aataatatga ttattttagc aataaaaaag ttatactgaa aatgggttaa tactgcttca
       61 catagcagtt tcatcgtaaa gcataagtaa aaaaggtcag aaatagtgac ctctttatac
      121 tttataacag tttatctcaa agctaactaa atatttgtaa aacaacgact tgttttaagt
      181 taatcataaa cttctttttt tctaatattt tttgctacta attgccactg tttttcatat
      241 atccaattag gatcagaaac aatcgctgca gaaactttgc gtgcttcttc taaaatagga
      301 taatcctcaa cgatatcagc tacttgaaat tctggaattc cagactgacg agtaccaaag
      361 atttcgccag aaccacgcat ttttaaatcc gactcagcca aaacgaaacc atctgtcgtt
      421 tctgtcatga ttgtcattcg ttttttcccc gaatccgttt tgggattagc cactaaaaca
      481 gcgtatgatt gtttatgtcc acgaccaaca cgcccacgaa gttgatgtaa ctggcttaat
      541 ccaaaacgat cggcatccat aataatcatg atcgttgcat ttgggacatt tacccctact
      601 tcaataactg ttgtggatac taaaatatga ctttttttat ccttgaaatc ttgcattata
      661 gcatcttttt catcattttt catacgtcca tgtacaagag caaccttagc aattccttca
      721 aaataagtag ataattcagc atgcaatgct actgcattct ttaaatctaa agcttctgat
      781 tcttcaatca acggtgaaat gacatacact tgagcatctt tttgcaattc accttttacc
      841 cattccaaca cagtccctag ctgctcgtgt ttcacccagc gtgtcataat aggtttacga
      901 cctgcaggta attcatcaat aacagaaaca tccatttctc caaaagctgt gattgctagg
      961 gttcggggaa ttggggtggc tgtcatcatt aaaacatcag gattttctcc cttttcacgg
     1021 aaaattctac gctgtttaac accaaaacga tgttgctcgt ctgtaatgac aagccccagt
     1081 ttatggtact gtaccgagtc ttggataaga gcatgagttc ctacaatcat atcaaccgag
     1141 ccatttgcaa tagctgctaa aaccgtacgc ttgacagcgg ctttcatacc cgaagttaat
     1201 atagcaattg ataaatctgg aaataactct tgcagactaa tatagtgttg ttcagctagg
     1261 atttccgttg gaaccatcaa agccgattga aaacctgctg tataagctgc atacattgat
     1321 agaccagcaa tgactgtctt tcctgatcct acatctcctt gcaataaacg attcatatga
     1381 gctcccgatg acatatcaga taatatgtca tctaaagagc gcttttgagc atttgttaga
     1441 ataaagggta aagaggaaat ctttgtctcc atagcatgtt tactataaag aataggcaaa
     1501 ccatttgttt cagatctatt ttcggctttc aaaacttgaa ggttcatttg aaagtaaaat
     1561 aattcttcaa atttaatccg acggagcgct tgcttatact ctgtgatatc ttttgggaaa
     1621 tgcatagcta aacaagcctg actacgaccc atcaatcggt atttttccaa taaagtagct
     1681 ggtaaatttt ccttcaattc caaatgcgca tcgatttcaa aagctgactt aatagcttta
     1741 atcaaagtag actgtgaaat tccctgagct acgcgataaa caggttgcat gtcatcttca
     1801 acttgagcta aaaccttcat cccagtaata gccgatttag tggcatccca tttaccaaaa
     1861 acagctacct cttgaccaag ttctatttta tcagctaaat agggttgatt aaaaaaacta
     1921 acatttaaga cagcttcccc ttgacgcaat ttgaaactta aacggttacg tttaaaacca
     1981 taatattgta cattagctgg agtaacgact aagcctgtaa tgactgcttt ttcaccatcc
     2041 actaaatcaa aaacagattt tgatttaaaa tcttcatagc gaaacggata ataaagcagt
     2101 aaatcttcta ctgtataaat atctaatttc tgaaattttt ctgctgattt tggtccaaat
     2161 ccctttaagt tggacatagg agctgttaat atcattatct ttttcccttc acaaaaactc
     2221 ttgtcagatt gaagacaaag tttgtcgtga tactttcctt aggtggtgct tacggcagcg
     2281 acgttctttg gaattccatg cctttatttt tgagcctgag gtctcaaaaa tcccgagtgg
     2341 cgtcaatctc gtattgacgc cactctttta ccacagcaaa aagcatctgt tttggctcac
     2401 tttgtgtgta aaaatcggaa accgaatgtc aaatcagcag agctatgcat gctttttgag
     2461 cataaaactg gagttgtcta cgttctgact cttgtatcta ttatacaaga gttcctattt
     2521 attttcagat aaaagccttt tagtactttt aaacagttct aggggctcgt taaggtagca
     2581 tttgataaat ggtatcgcag acactactta gaagttcttc atcatgtgaa atgaggatga
     2641 caaccttatg ttgggtcttc agctgcatga gaagattagc taaagccttc atttgtaaca
     2701 aatcaagtcc gctacttggc tcatcaaaaa ttaagatatc tttatcagcc aaaagactag
     2761 cggcaatcat cactctttgt tgctcacctc ctgacaaact agctggatga cgttctaaaa
     2821 gagtcgttaa agataaccgc tctattactt ctgtcgtccg tggatgtcgt tcatggccca
     2881 agttgacttc ctttgaaacc gattctgcaa atagttgcaa agaaacttct tgtaagacaa
     2941 tactagtctt tgataaacgt tgcttggcag ataaaggtat gccttgaaac ttaatagttg
     3001 cttttttatc gtctaagata ccagctatat aataaactaa ttgcgatttt ccaagcccgt
     3061 ttgatcctgt aatgccagaa atacttcctg cagcaaaact aagctgttca atacatctaa
     3121 gtattttgct tcccgctcta actgttagat gctcaataca caggctatca tctgggcgat
     3181 aatgttgact ctcaatctta ccagctaaca caggttttag gtcagacaag tctaagcgac
     3241 gtagtcccat atcttgccgt tgttcatctg tcaaggctag caaatcttgt gttgttaact
     3301 tatctgttaa tctaccattt ttaaagtaga aaaagttatc tgccaaatcc atcaagtaat
     3361 gtaaacgatg ctcggctaca ataatggttt ttcctgctgc ttttaattgg gtaagatagg
     3421 ctttaacagc agctatgcct gcactatcta agttagcagt tggctcatca aaaagcataa
     3481 tattagtacc ttgcataatg gccgttgcaa tagcaactct ttgtttttgc cctcctgaca
     3541 atccaaacat atccttgtta aggagctctg caaaagcaaa atcttctgct aaagtccaaa
     3601 gacgcttcat gataaccttt gcatctagac cttgattttc acagggaaag accagttcgt
     3661 gttggacttc gcgatagaaa aactgactgg ctggattttg aaaaacagag gccacagatc
     3721 tagaaaatgt ttcaacactg tctctgcctg cttggcaatc agccacatct agtctacctt
     3781 catattttcc agcataataa tcaggaatta tgccattaag aaattttaaa aaggtagatt
     3841 tacctgaacc agaaggtcca cacaaaacaa tgaattgtcc agaggcaatt tgacaagtcg
     3901 atacctgaca agctggattt ttttgatcat gataggtaaa aacaagttgt tctgctgaaa
     3961 tcattgaagt atcgtgatga ttatgatagc agtaatccaa atctgcaccc cccaatcttt
     4021 ccatgttaag tgtgagctaa agcattcact ggtgcctttg ttgactgcta gtcctttagt
     4081 tagactagcg atagttagtt cttgactact tcttatcaaa gataaaagca atggaaccat
     4141 taaatactcc aagtattgtt taggtctgat caaaatagac cattttgtta aaataatccc
     4201 cctgattgtt aaagagcgat gaataacaca acattcttgt ctaatcattg gtatgaaacg
     4261 gcacataacg gctaaggtca atagccagac ttctgggaaa tgccatttgc gtaatccatg
     4321 aaccaattcg tagatggtag ttgtcttaat agtaattaaa cctgctagta aagaagggaa
     4381 aactaacctt cctgctattg agacaaaact caataagtga tcaagataag aagggaaaat
     4441 agatagcggg attacagata gaccgatcat taacagataa acaaccgcca acttgaacgc
     4501 tagctttttc ttatttaaag cagacaaaag taataagaga aaaataacaa ttataaattc
     4561 taaaaagcca tcaacacgaa aaaagaagca ggcattggca agtaccaaca aaagcagttt
     4621 ggtgcgaaca tcaagcctca tgataacaat cctgatttga taaaatgttt ctttagtaaa
     4681 taatgtgcaa aagctgaccc taataaggct cctgcaagaa caattcctac aaaccaaata
     4741 acatgcccta aactaaaatc atacataatg cgattgacat aggtcatact tttaccgcgg
     4801 gctaacaaac tttcaacata ggcatctttc aacaaccaca tcagcaaaat agggccacta
     4861 ttgacaaaag caaaaaccat ataagatagg tcattaaaaa accttgactt gtattttcct
     4921 aaagaagcaa taatatccgc tattaaaccg aaaataatgc tgggaaacat cgcggcaaaa
     4981 aagtgaccac taaggaagaa aaaacctccc atcatcagtc ctaataatgt tattggccca
     5041 aatgtttgca atttagcaat caaaagaaaa taaattgttc cccccagtaa agctgcaaag
     5101 gcaggggcat ataacatatt tcctgagcga tcaaaaaaga tgttaataaa cgtgcctaga
     5161 ccaacacaaa taaagtagag cgcggcaaat gcgcctgtta tcataatatc ttttattgtt
     5221 aactgtttca ttttttattc acctctttta ggaaaccatt ttttacgcaa aatagatgat
     5281 cagcacaagc tagggttgat ggcctgtgag aaattaagaa gaccaatcct tgacaatgtg
     5341 ttttaattaa atcaagcaag atagcttcat ttagagaatc taaatttgac gtgggttcat
     5401 caaaaatata gcaactcgca tctttcaata aagctcgcat caactctaaa cgttgacctt
     5461 ctccagctga aaagtcagaa ggactcttga taatcgtatc caaaccttcc ttacaagcta
     5521 acagtctgtc tttcatacca caagcctcag ctaaattcca aatggactca tctgaaatat
     5581 cttgacggcc aaaggtaaga ttttcacgga tagactgttg gaaaagctgc gctgtttgtg
     5641 gcacataagc aatagtatct tgtaatttag cagcatttag taagcaacta ttcctatcat
     5701 taagaaaaat atctcctgtc ttccaattat accatttcat aattaatttc accaaagttg
     5761 atttaccaga tcctgattcg cctttaatgc caataatccc cttttcttga aaggtaactg
     5821 ataaatcctt aaaaaccagc tcttggcgct ttggataagc aaaactgagg tcctcaaaag
     5881 aaacactcct taaacgatct atctgttttg tgccttcgtc tactatgaca ttttcgtcta
     5941 gaaggtcaaa aatatttcga gccgcattca tagcacgctt aaagcctaat ggcaaacgtc
     6001 ctagttctaa aaaaggagaa aacgaagcag tgaaagcaat aaaagttaat aagcctttat
     6061 caaatgataa gctgtcatgg catatcccat caaaaaccat ataagaaaat gctaagatca
     6121 ttaagccaag ccagaaaaaa gtcaatgcca tttgcaaaaa ttgggcttgc gctacgttac
     6181 gatcaagagc atttacatga ttactttttt ttattaatcg ttcaaattgc tcgtctaata
     6241 cctgaaattg caaaagatct ttgactgatc gtaaactctc taaaaaataa gacaggtaat
     6301 cttttcgacc ttcattttgg ctttttagta aaacctgtaa aatattagca aaataaatgg
     6361 gtataacaat ggctaaacaa gcataggttg ccaaagctaa taaggctaac tgccaactac
     6421 tttgacaaaa gtaccagaac attaaagctg cagacaatat tgctgtacaa ataggtgcga
     6481 ttgtgtgggc aaaaaaaact tctaatgcct caatatcttc tccaatcatt ttaagcaaat
     6541 aaccactgtc ttgactatcc aagcaagctg gagaaagagc tcttagtttc ttaaagatca
     6601 agttcctaaa agctgctaaa ctatgaaaag caacaaaatg accaaaataa tgctctccat
     6661 aacgaacaaa acctcttaaa aaggctagag caatcaaaag atataaagct aatattggaa
     6721 tcacttcttg tctaatagct agtagtccta aataagctat tccagttgga atacttaccg
     6781 tgatgacaaa acccataaca gcaaagccaa cagccaagat aatccaaggt agcagagttt
     6841 tcattagggt taataaacgc caaaccaggc ttaaggtaga tctgttaggt ttagccataa
     6901 atacttgcct ccagtcttgc ttgagtatca actaggtgac gataagttgg ttggtcccga
     6961 taaaggtcgc aaggtttgcc taaacaagca ggctgccctg tgcttaaaaa gagtacttgg
     7021 ttagctcctt tcagtcgaga catcttatga gtaatcacaa taactattgc cgtcttagct
     7081 aatctcgtta ttaaattgtc aataatacgt tcattttctg catctagact agatgttgcc
     7141 tcatcaaaga tataaagaga cctcttactt aatagagctc ttgcgcaaat cacctgttgc
     7201 ttttggcctg gtgataacag gttaccattt tcaccaacta ttgtgtcaag accatctggt
     7261 agccagttga tgaagcttaa caaaccatgt tgatctatcc aatctaagat ttctttttta
     7321 gagagatttg cggctaacct taaattatcg taaatgctac ggttcaataa ggtagattgg
     7381 tccgatacat aaagaacctg ctggttgata gtttcttgcg acaaattgtc actgtctaaa
     7441 ccgtcaaata aaatatgccc agtcgttgca gactggcgtt tcaagaggag ttgagctaga
     7501 cttgtttttc cttgtcctga cacccccgcg atagctgtta gttggccctt cgttaatgtc
     7561 atggtaaccc cactaagcac tgtttttttc tcataagcta aagaaatatt ttggaggtca
     7621 atctggttaa agtttattgc tgttttactc ttgttatctt tccttgctgg aacactatcc
     7681 aagaaactaa agatacggtc agccattttg gtattcatca tgaccaagtg catgccataa
     7741 ccctgctcac gaatcggtgt aaaaaattct gtagcaatca agagaaaaaa gaggaaatta
     7801 aaaaaagata actgacctgt tgccaaagct tgaacggcta aaaaacctga caaaccaatt
     7861 cccagataca taactgcatc catataacca actgcttgta actgaaagcc aagcaaagac
     7921 atggtagcct ttcgaaactg ttctgcctta cccgaaaatt cttgctcgta acgttctgtt
     7981 gcttgataag aatacagtgt attaagacct tttaagtcat ccataaataa attaccaaca
     8041 tccatataag aagaccaata atgactcata atttgcttag accgcttttg catagcaacg
     8101 attgaaagtg gaatcagagg cagaactcct aaaaagacaa ggcctgccaa tggataaatt
     8161 aaaaagacta gtatcataat agttgtgcag ttccacttgg ttctcataga caaagacaaa
     8221 tagtaaccat aataagtatc caaactatca atcccctgtg aagccaacgt taaaatatca
     8281 gcatcactgg catgagcatc aaattgcccg tctaaatcaa taaaagcctc aaagaaagat
     8341 tgtttgagtg aatctctagc aaattgtgaa gcgatccctt gcagttgctt gcctaatata
     8401 gcaagaacaa agcctaccac atttaaaagt aggagtaaac ctgccaagcg tcctaaggca
     8461 atagcatgac ccaaaataaa ggtcgaaaac gttttggcaa tgaggtaaaa actgatcatc
     8521 ctcatcacaa attgtaacca agataaaaag gctgacacat aaagcaaata cctttttggt
     8581 gcaattcgtt cacgtaatcg ttttaacagt cttttccttt ttccccttga tattgtatct
     8641 tctgtttcca tcatctgttc ttgttcctat ctctcctttg agttctaata tcattggttt
     8701 cattgaccaa tgaagtgagg acaaactgtt gaccatttct ctcaacaagg ggcaattcaa
     8761 caccaaagac atctctgata aactgttgat caaggaggtc tcttggttgc ccttgggcat
     8821 aaagtcgccc atctttcagt ccaataagat ggtctgaaag agacaaggcc tgattgatgt
     8881 catgtaatac taacacaatc gttaagccta gctcttggtt gattttagta atcagcttga
     8941 gaatgtcaag ctggtactta atatccaaat aagtcgttgg ctcatctaaa aaaataatat
     9001 ctgtatcctg ggcaagggcc atagcaatcc aaaccctctg ctgttcacca ccagaaaggt
     9061 gttggatgtc acgataaaca taatcactca aagccgttac ttctaaggcc caagcaaggc
     9121 gttcctcatc ttctttggta gtagttttaa aaaaagaacg acgggcaagc ctagccatgg
     9181 ctaccaattc acccactaac aaaccttcga ccacttgatg gtattggtgt accactgcca
     9241 cttttttcgc aaaagccttg agagaaatcg ttgctaattc ttcctgctca agccaaacct
     9301 gcccttgttt taacggaagg tttttggtta ataattgtaa taaggttgac ttgccactgc
     9361 catttgcccc cataatagtg gtaattttcc cttttggaat gctaaaggtc aggtcatcta
     9421 aaacaagttt ttcctcataa gcaaaggaaa ggttttgcac ctgaatatga ctgctgttct
     9481 tactcatata atatcagacc tccttagcag gtaaataaag taaggcccgc ctacaatact
     9541 cattataatc gcagggctaa tttccaatgg gtaagcaaga cttcttccta aagtatcggc
     9601 tagcaaaaag acaaaggctc caagcaaagc tgaaaaagga attaagattt ggtgcttact
     9661 tccaaccagc aagcggctca tatgagggac aatcaagcct aggaaagaaa ccactccaac
     9721 gatcgaagtg gctaccgaag ccaataaaac agcaaccgaa gaaattccca accgtaacgc
     9781 tgtagcatcg attcctaaat gacgaatcac ctgatcatct aaaagaagaa ggttacaggt
     9841 ttttgacaat aacaaagcta gtaacaagcc aatgaatgta taagggaata aaacccctac
     9901 atcagcccat gttttttgac taatatgacc tgctaaaaga gcattgacca taggactagc
     9961 tgaggtgaaa aaactggtta aagcagttga taaccccata aataaagcat taatagcaat
    10021 ccctgttaga ataagccgaa taggattaag ccccttcttc catgctaaac cataaatcag
    10081 caggaaagac actccgcctc ctaaaaagga tacgattgga ccatacagca gcaactgcgg
    10141 tagaagtaaa ctagagacta aaaccataaa actagcacca ctacaaatcc ctataatagc
    10201 agggtctgaa ataggatttt tcaacactgc ttgaaaaaga actcccgaaa cagctatccc
    10261 tgctcctgct aataaagcaa tgacaattct tggaaagcgc aaatcataaa tcaaagccac
    10321 ttgggggtca taagccacaa acagtccctt gacaattgcc tcataagaaa ccgccaaacc
    10381 accaagggat aaggcaataa ccgccaaaaa caggagactg agaattaaaa gaactagata
    10441 aagaccactt ctgaaacgtt ttttagccag tagggattga tccctttgta aatctgatgc
    10501 tgtcatgtta cgaatgatct cccacgtggt caaaaagctg tgttaaggtg tccaaggctt
    10561 ctgggtagtt caatttagca ctcatgccaa acagggtatt gtccaaatca tagactttcc
    10621 cttccttgac tgccgtaaaa tgtttccaaa tatcattttc agcaaattct ttgtcaaaca
    10681 tcacttttac cttgtctgga atggcatgag ctgttcgtaa aatcaagtca ggctccttag
    10741 ccagcatgtc ttcaggatta gctgatagaa attctttctc atctgactga taaacattct
    10801 caccacctgc caaatccaaa agattcccta cataagattg gttcgtcgcc accaaataac
    10861 tacctggcaa gcccataaga ataagcactt taggcttttt cttcccctta cgtttagctt
    10921 ggaaagcacg ataatagtcc tggtattgct ggcgcaattc ttttgcttct tgttgacgtt
    10981 ggaaaaggtt ccctaaatca tcaatggact ggtacatgcc ctcaacactt cgtaagttca
    11041 aaaaaccata ctcagtatcc aatttttgat acttgggttc caaatcttct tgtaaagaat
    11101 tgggactcaa aatccaagtt ggtttcaaag aagcaatcaa ctctatatca ggattcatgg
    11161 gtaaacccac acgcttaaca gcatcatagc gtttaggaag ggtatataat ttactatcac
    11221 aaaccccaac gaggtctaaa tttaaacggt cacagatatc aaccacagca accgaagtgg
    11281 ctacaattct ctgctgttca gtctctttag ccgttttagg gtgctgattc acacaagcta
    11341 ccaaaaagaa ggccagtaag gctagaccaa ttcctttaca tcgttttatc attttttttc
    11401 ctctttttcc aaacccatac agcaaaccct cctaacatca gaaaaaaagt tggaaagtag
    11461 taaatcatga ttgataagtc ttttttagac cgaaacttat cttctttttt taactctaaa
    11521 gaagtcgtta agcccatctt agaaggaaga atttttttat ctgatagact cttgttattt
    11581 gatgagttgg ctttaggctt attctgagtt atcatagcac ctgtgtgaga ctcatcttga
    11641 ctttctccta gttttgtatc aacaggcttt tgattgtctt ttacttcttg attttgagaa
    11701 ttgtctgttt cagtaacaag ctgggccaac atattacctg aatacttttg tattaactct
    11761 gaagctgaca ggtaaaagac cacttctctg cccataggtt caacaaacat gcttcctcga
    11821 atgatactat ttacagtagg caaactaata gcaatatcta gtgttgtccc attggtatca
    11881 gtaccttttt gggtgatatt gtaatccact gcctgaaagc ttccagttcc tccaggttgt
    11941 atccagaact gataattgcc cgaataatca gctaagctca tacgaaaagt aagaacgatc
    12001 tttccagcat cagatacttc tagcatggca tcactataga cagtcccttc aaccatacct
    12061 tgaccaatat caaaggaatg ctcccctccg ctatcttcta tctgcccaga tatcggatga
    12121 cgataatttc tttgaataat acatccataa atttgacctt tatctgcata cacaacacct
    12181 gtcattgttg ataaacttat catgaacact aatattacct gcaacaattg ctttattact
    12241 acctttgtca tatgctcctc ttgtctatct tttcttaaac atcttatttc attttttgaa
    12301 tgaatcccat tttataacat ctccaaatgt gaaaaacaca cctatcttgc gactacttca
    12361 acctgtatca ggagtcctgt cggaaatagg tatgttttta gctcttgctg actagctttt
    12421 ttgttatttc acttggtact aagtttctta tttaaataat gtctttcgac caataatgaa
    12481 tcccagagct acgatcataa agctagatag acctgcaatt aagtgataac gagagctact
    12541 ttcttcacca tttgattgtt gattggaacg atgtttctta tcagattttt tagtcttagt
    12601 atcttttgcc gttttacctt caattgatgt ttgatggtca cgcactaact gcttcaattt
    12661 ctctgcctta tcagtatcat ctgtcttaga agtttcttga gttgattggc cggttgcttt
    12721 tttagccagg agatcagtta agttagcaat accagtagct gctgaaggag gacttgtagg
    12781 tgttttttct tgttgacgat tttgaggtcc tttcaactga tctgttgaag ttagatggct
    12841 attttcttgt ggattattag tttctttgac aacctttgcc ttctctgttg taaggcttgc
    12901 ccagtctaaa cgcataaaaa cggtttgaag gccagaccct tttgaaatgg catccatgat
    12961 aggcacaaag acctgtaatg gcacaagtcc gtctttcttc gcttgttcaa tcaatttcat
    13021 acgcagcact tttggatagt tttttccata acgatctgcc aatggtaggc cagttacatc
    13081 cgtgaaataa gacataacct ctgccttttt tgttcgacca actggtttac cagctaaatc
    13141 tctttggtaa ccatctacga aatagctcaa ttcaccaagg tagcctaaca ttttaccaac
    13201 ctttatacct ctaaactcaa cttctaaata ggaaacacct tttttaacta ccaaagtcac
    13261 tcgatgatta atagccttgt ttgacatgga ctcagatgct aagtcagttt ttaacatgct
    13321 ggcatttaaa tagtaaatac catcacgcaa ttgtttttga tttaatgctc taaggccttt
    13381 ctcaactaaa tctttctgat gtgaatgtgg tcctttcgcc acaaggatat cattagatgt
    13441 caaatagata tgttcttttt gagtagcaaa tttctttgtt attaaagctt tgcgaatccg
    13501 atatgtacct ggatctttta aagaaaactc tcccgttaag tcatctttcg gatcatttga
    13561 gagaagcttt tcgtcaaccg tcacatactg tccattggaa gatttttttt gcaactgaat
    13621 cacaatactc caatcgactt gcatatcatt aagtaaagag acagtatctg aacctttttc
    13681 ttgtaacaat tgttgatatt cttcaataga cactagttct ttatcaatgg cagaatttgt
    13741 tttttgctcc caataataca aatctaaaag actgaaagct tgatgatatt ttattttttc
    13801 gccatctaag gaagcttcaa gttttgcaat atgtttttgt ggagtcagtt tgtgttgtcc
    13861 gataagagct cttacttttg gactcacact ttttatctga ttgaacttca catctaaatt
    13921 aagcgtttca acatctggaa atactgattc ttcaacctga gtaagcaagt tattgaaaaa
    13981 atcaagtttt gttaattggt tattctgttt aaatatacca tttggaagat ttgaaatttc
    14041 attagttgat aaatcgagta cagataattt aggaagattt ttaaatgaaa tattatcaat
    14101 acgagtaata tgatttctac ttgccacaat agtgcttaag gcgcgcaatt tttctattgt
    14161 ttttggcagt agtgctaaat tattttgaga taagtcgata aagttaagtg atgttagagg
    14221 ctctagcgct ttttcaggta tctcctcaag actattttct gcgaaaccta atgaagtcag
    14281 gcgagacaat ccttcaaatg ggttatcaca aagtcggcca atacgattct tggaaagatc
    14341 aagttgctcc aggtgatgaa gcgactggaa tagtcctcct tcaagagagt gaataaagtt
    14401 acttgataag tagagttctc ttaattgagc attgctttta aatgtatctt tgtctagata
    14461 agttaaatga ttacttctta agttaagaaa tcgaagttgc ttcatttgac taaataactc
    14521 ttttggaatt tccgtaattt ggtttccatc cagatgtagt tctgtaatat ttttagcatg
    14581 tttcaataaa gaaatatcag ttaactcgta atggtctaga cgcaactcgc ctcgaatctg
    14641 ttctaattcc gtttttgata atttaccatc gccgtctaaa tctttgccaa gtttaactaa
    14701 aactttttca aggcgttcag tcccaacccc tttttcttta tcatcagttt ctacctgata
    14761 accactccag cctttggtaa cggtcttact aaaggtcatg tcaagtttgg tgtatttgtc
    14821 atagtggttt aaatcacttt cttgacctcc catggctgat accaaaacag cacctttgtg
    14881 taatttatcc aaatcatcaa taggcatggt aaattcgctt cgaatatagc taccattgat
    14941 atctttttgg ccaacttgtt tacgcactgc tgctgggtag gtccctttgc tttcaataga
    15001 aaagtcaatc aaaaattgtc ccaaagcagt attaagcatg gaaatttcca ttgtaccatc
    15061 tgctttaacc actaatttgg ctcttttatc aaaagcacct tgaagcatgg aggactcttc
    15121 tgagttttct ttattagctt taaagtttag cgtataggtt ccttctgtga gattgttaat
    15181 agaaacctca cctgcttgat aagactcgat ggtatctttt aacagtcgat gagtatcggc
    15241 gagtagctta ctatctttga tttctttgta agaatccttg atgacttgaa gtttctcagt
    15301 cagatctttg accgcgtctt tgttgctttc tttagcaata atcgcatctg cttctttgat
    15361 agctttttcc aaagtggtga catccaactt tgttgattgt ctgtcttcag cagtcacatg
    15421 ttgtttttgt ttggcagata caaaatggat ttgaccatct ttcttggtaa cggtaatggt
    15481 aacgtcttca aatccttttg aggatatcac gattgtattt tctccatctt tgaaagcttt
    15541 tgttccaaga tgaagccctg tcatattcga gacccagcca ttagtatctt ttacagaatc
    15601 tgaaataaga tctttataaa ctgtaccatt gactgtaacc tttgtgattt gctgagtcaa
    15661 tgcttttatc tgtttgttat cagaataacg atcaatttct ggaaataaaa ttgcaccatc
    15721 ttcttgactc aattttgtta ttaatgacaa gttagcagta tttttcccag atttaacaac
    15781 tttttgtgtg cctttgtttt gtggcactgg tttatcactg agcacatctt tttttaatga
    15841 atcctgatga tctgttgttc ctaatttttg agctgaaata aaggtcactt tatcgccctt
    15901 tttaataaag gtaattagga tatcaccatc ttttttatta acaatagtca attcatgctt
    15961 accgtcttta ataaggttag cattgatctt aatcccttgg tagttaatat caaaggttcg
    16021 ctcgccttcc aggctttttt catagacatc attatcaaca ataacctttt caatatgttt
    16081 ataatactct tttccagctg attgactagc ataagggcct atctcttcaa ctaaaagtcg
    16141 attatcctga gttaaagcta ctgttgtcac gagttgtgac tgaactaaag gctcttgtga
    16201 ttttacagtt tgagtagcct gaatgagaac aagggcagat attgccacaa acgcacattt
    16261 gctgattttt ttcattttca atcaactttc taaaaatttt tatgaataag ctaacttttt
    16321 tattaactga acttaatcta tcactttgtg attattttgt caagattgtt tccaatggtc
    16381 caattgtctg ttaaaaagct ccactatgtg agccaagaca ctagcaataa gcctggattg
    16441 ataatgatga tatctctgat aaaagaattc ctctacaaca atattactga gataaagcta
    16501 gccttaggat agttattact agggctgatt caatcattgc ttcattcaca aaacatgtaa
    16561 cacgttataa gctccataat tgtgttagga gacaacatga gatgtcacta ctgcatattc
    16621 atcacaataa aaaaagacaa tagccctaat cgtgctattg tctcaaaatc atttatttac
    16681 ttgaaacttt atcgtgttac accaacagtt taaaaggcct aactcccgct aagaaaatta
    16741 agccttaaga aaagtcatta gttattagtt tttactcttg ccaataacat atgttagctg
    16801 ttcagcctgc tgagctgtaa aggtacgata agaaatctta cctaagccga tacagttaga
    16861 ctctgaaata agaatagacc catcttttct aacatcttct acaattgata cgtggccata
    16921 agtgccatca gcgcctgctt gcccgggtgc aaatgaaata gcataaccta cttttggagt
    16981 ctttgacagg gcataccctg ctttatactt ccaatctcca ccatttccca taaaaggatc
    17041 aaattggtaa cccaattctt tggcgcgatt atacacatac caagtgcatt gtccccaagc
    17101 ataactcgaa gcttgataac ccaagacatc ataactctta gagagcttat aacctgctgg
    17161 cacagatgca aaactagctg atgactgcac tttcaattcg gctggaatgg ctggtgtgcc
    17221 accatggtca tcaatccact tatccaggtc ttccataatt tgtgcgcgac gtttaccact
    17281 accagtagta tcagtaaaat aaacaccccc gtcacttgca aagtttaatt gacctcgtga
    17341 aaacttagcc gcttttaaat cttgaagtgc aaaattgcta tttttgtttt taataatggt
    17401 gtcttgtgtc attttgacaa tagcactatc atcattaaac ttacttgctt gagtcggatc
    17461 tagatcaaaa gctgcatagc caaacatatt agctccaagc aaagttgcaa tcccttgagt
    17521 tcctaaagaa ctctcagaca tcgcaatagc tacgatagct cgaacatcca gcccactttt
    17581 cttttcccat tgcaatagct tctcaccatt aatacgtgtg ctgtcatagg caatgcctgt
    17641 tgattttaag taactatcaa tctggtcagc tttaatacca taacggcgag ataaaagatg
    17701 gtgggtatag gcatttttac cactccaatg ctctacatat gccgcgtatg tgttgacaga
    17761 agggatatct atctcactca aatctaaatc tgatacgtaa ggtgacaacg actgaatagg
    17821 agttcttgcc tctggcagtt gtttcggcaa tgaagaagca ggtgccgtat caactttaga
    17881 tggtgatggt ttgggctgat cagtcggttt tggctggtca gttggtttcg aatggtcagt
    17941 tgatttcgaa tgatcagttg atttatcatc tacctggttt tctgcttctg ccttgttgtc
    18001 cgaagaacct acagcagact gactagaatc gcttcttttt ttatcatccg cgttaacaag
    18061 actattagag tttgtttctg cagaagcatc aaggggacct tggtcagttt tatctgatgt
    18121 tgtaggtgct gcattattat tattttcctc ttttgaagaa gaatcactgg tttcatttgt
    18181 agttgcttta tgcgtctcaa gcattacatc ttgagccaac actgtcatgc tttctgctgt
    18241 cggggctaag agacttagta gcatggcaac tcttaatagt ttgtttttat ccatatatta
    18301 attagtcact tctttctaat gtcctcactt tattataaca ttaaagataa gcacaatgca
    18361 attattttta cgtgattttc ttaatatatc cgaggaatac ggtcacttaa aaggcataga
    18421 acttcataat tgattgtatt acggtaattt gcgatatctg ttgtagaaat atttttttgc
    18481 tgattgctgc caatcaaagt gacttttgtt cctaaaggat atgctttggg aagtcgtatg
    18541 gtcagttgat ccatcgatac acgccctata atttcacaga attgtccatc aactaacacc
    18601 gaaaagcctt gcatgttcct ggtccagcca tctgcataac cgattgggac ggtccctaca
    18661 tattcagact ttttggcagt ataagtagct ccataaccga ctgtatcacc agctgaaatc
    18721 atcttgacat gcactaagct agattctaga gataaagcct cttgcagtgg aaacggtaag
    18781 cttagatcag aaccacttgg attcaaacca taactgacaa ttcctaaacg aacagcatta
    18841 aaaatggtat cactatgcca gatacttgtg gctgaattac tagcatgtac taaacgaggc
    18901 ttatcctcaa gtccagctat cagcttttta aaaaactgta actgctggtt aaatttagta
    18961 tcatctgcct catcagctgt ggcaaaatga gtgaaaatac cttctacatc agcacccaac
    19021 tcttttagac tatcaatcaa taaattgact tcttttgaag aacgaagccc gatccgcccc
    19081 ataccagaat caacttttac atgaactttt aagccttgac attctttttt ctccagtcta
    19141 gctaaagcta tccagtctaa actagcgatt gtaacagtaa tagcattagc aactgctaac
    19201 tctaattcat ttggcaggag gactccaaga attaaaatct ctttatcaat acctgcttga
    19261 cgtaattgca aagcctcatc aagatttgac acacagtacc catccacttg aggtaggagt
    19321 gcttttgaca cctggacagc accatgacca taagcatcag ccttgacaac tgcatacgtt
    19381 tttaccccta gtggaatatg cttttgaaca ctggcaacat tctccttaat agcttgtaaa
    19441 ttgacccttg caactgttgg gcgatggaaa cttgaaatca ttttttatcc tccaaaataa
    19501 cactagcctg tacataattg ccactatgtg agatgctaat aaaactattt cctttaaacg
    19561 gagattttgt cagaatggga catcctctaa catcatttaa aatctcaata tcttgaaagg
    19621 ttaaccgccc aatacctgtc cctatagcct tagcaaaagc ttccttacct gaccagcgtc
    19681 ctgccaaata gctgagtcga cgtttgtaag gaaaactctc aaaaatagcc aattcctgct
    19741 cagttaaaat tttttgagca aagcgaggat ttctttgata aactttttca atagctgaaa
    19801 tctcttgtaa gtctattcca tgtccaacaa tcattacttt ccaccaaacc ttatttcatc
    19861 ttaatgttag aagatttaaa cagtgagaag ctgagaatta ttctcagctt ctttctatat
    19921 acctaacttt gtcctgttgt gtctcgttct tatgagaagg atttacgacc gtgacaattt
    19981 ttgaattttt tgcctgaacc acatggacaa gcttcgttac gctccacttt gggtaaatca
    20041 tcggtgttag ctgactgctg cgattggatg ttttgaggtg ctgctgttgt ggcacgttga
    20101 cttgcacgtt cacgttcttg ttcgtgaatt tgtgctttca tcatggtacg tgttacatca
    20161 aactcgatag caccaatcat atcttggaac atcttgaaac cttctgcttg gtattccacc
    20221 acagggttat tttgagcata cccccgaagt ccaacagcat tacgaagttg atctaaggca
    20281 tcaatgtgtt cagtccattt gttatccaca atcatcaaaa tgagtacttt ttggaattca
    20341 ataatagctt cttgatcacg aagttttgat agttgttggt catagatagc aagcgctctt
    20401 tgataaagct tctctttgat ttgatcatct tttaaaccac gtaactcttt agcactaata
    20461 gactcttctg gtaccagcga ggtcctagca aaagttacaa tagcatctat agcatcttta
    20521 cgattgctac gtgcatgagc atctacagca cggtcgatag tacgcttgat catagcttta
    20581 atttctgggc caagatctcg attagcagtt atgacatcac gacggttagc atagataatt
    20641 tcacgctgtt cacgcatcac atcatcgtat tgtaagacct gtttacgggt atcgtagtta
    20701 tttccttcaa cccgtttttg agcagattcc acttgacgcc ctaacatacc tgatttaata
    20761 acagtgtctt cttcatctaa tttcatccga tccaaaaagg cttttatacg atcagagcca
    20821 aaacgtctca tcaaatcatc ttctaatgaa agatagaatt gggattcacc tggatctcct
    20881 tgacgacctg aacgtccacg aagctggtta tcgatacgac ggctttcatg acgctctgta
    20941 ccaatgacac ataacccacc aagttcacga acaccttcac caagcttgat atcagtacca
    21001 cgaccagcca tgttagttgc gattgtaaca gcaccacgtt gcccagcatt cataatgatt
    21061 tgagcttctt taaagtgatt tttagcattc aaaacctcat gaggaatccc tgcttcaacc
    21121 agcttgcgtg aaatcaaatc actagtttca acagcaaccg tacctacaag gataggttgt
    21181 ccttttgcat gacgcgtttt aacgtcttcc acaactgctc taaactttga ttctaaggtc
    21241 gggtaaagca aatcagtgtg atcaatacgg gcaattggac gattggttgg aattggaata
    21301 atacgcatgt tataaacttc gcgaaattct tcttcctcgg tcttcgcagt accagtcata
    21361 cctgccaatt ttttgtacat acgaaacata ttttggtaag tgattgaggc gctggttttt
    21421 gattcttcct gaatacgaac gccttctttt gcttcaatag cttggtgcaa gccgtctgag
    21481 aagcgacgcc cttccatcgt acgacctgta aattggtcaa caataagaat ctcaccatct
    21541 tcgctgacca cataatcgat atctaacaac ataatatagt ttgcacgaag ggcgttgtct
    21601 ataaagtgag tcaaggctac attttcaata tcgtaaagat tgctcaagtt aaagtaactc
    21661 tcagctttat caatacctga atcgcttaat ccaatcgttt tagtgggcac atcaataaca
    21721 taatccactg acgtcagagt ttttacaaac atgtcagcac gaatatacaa ttgattggtt
    21781 tcagagctaa cagcaccaga aacaattaaa ggtgtccttg cctcgtcaat taagactgag
    21841 tccacttcat caaccaaggc aaaattgagt gggcgttgta ccatgtcttc ctggcgaaca
    21901 accatgttgt cacgaaggta atcaaaaccg acttcagagt tggttgaata agtaatatca
    21961 caattataag cttcacgttt ttcagcagga gacttagcag ctaggttgat cccaactgaa
    22021 agacctaacc agctatacac ttcacccatt tcggtagcgt cacgcgttga aagatactca
    22081 ttaacagtaa taacgtgaac accctcacca gcaatagcat tgagataaac tggcatggtg
    22141 gctgtaagag tttttccttc accagtacgc atttcaggga catccccgtt atgaagaaca
    22201 attcctccca taatttgaac acgataaggg aacaagccca acacacgttt tgctgcttca
    22261 cgaacaactg cgaaagcttc aggtaatagt tgttcgaggg tctcaccttt ttgatagcgt
    22321 tctttaaatt caagtgtttt tccttgtaga tctctatccg acaatgacgc catttggtct
    22381 gcgtaggatt ctactttttt tgcaattttt tctaattttc ttagttcgcc tttgtcattt
    22441 tcgataactt tgcgtagaat attggccatt ctctttcctt tcgatcatct aatcatttca
    22501 ttttaacata aatatgcagg cagttcaaga aaggttggta aagttatcag agaaacagag
    22561 agtcataatt ttatcctttt ttctcatatt gataccatgg tattaaacga gttgattggg
    22621 gtgactcaca atcatttcta attgaccatc aaatgaccac gatttaacat cgttaggcaa
    22681 gataaagtgc atgccttttt ctagctcata agccttctgg tccacataga gttttccttg
    22741 accttttaaa acactcacta aaagataagg cgcagcttgt ttcatgtcaa ccatttgact
    22801 agttacccat ttgtaaacag tgaaaaatgg cgttgagact aaagttgttg ctaccatatt
    22861 atccaaaacc atagtggctg gcacgctatt ttctggctta ccaatcgtta agacatcaat
    22921 agacttttca atatgaaggt cacgaagatt accattaacg tccttacggt caaaatcata
    22981 aacccgataa gtggtatcag atgactgctg ggtttctaaa ataagaattc ccttgccgat
    23041 cgcatgcatg gtgccacttg gaacatagaa aaaatcgcct gctttgactg ggacacgagt
    23101 cagcaaatca tcccaagcgc ctgcttcaat catggcacga aggtcttctt tggacttggc
    23161 ctgatggccg tatacaattt cagaaccctc ttcggcagaa ataatatacc agcattctgt
    23221 cttgcctaat tctccttcat gttcacgtcc ataagcatca tcaggatgaa cttggacact
    23281 tagccagtca ttagcatcta aaatcttagt taacagtgga aaaacttctt cctttggatt
    23341 cccaaacaag gccggctctt gcgcatataa tgtgtttaaa ggttgtcctt gataacgtcc
    23401 attagtaact gtcgaaacac cattaggatg agcagaaata gcccaatact cacctgtggt
    23461 gtcacttggg atgttgtaag caaagacatc tctcaacttg gtgccacccc aaatcctgtc
    23521 gtgcatggtt gattttagaa ataatggttc tgacataata ttcctcgctt ctgatgttga
    23581 tctctgttta ttatagcatg ttctagctga ctgcgctttc ttttactaga caagcaggca
    23641 aaaacagacc ctatttccct tgtgcagcca acttggccaa agcaaaattt cccagagtag
    23701 cggagccatt atcagcaaca gctggagtaa caatgtagtc tgtcaaatca gggactggca
    23761 aataaccgct taaaagggta gtgaatttat catgcacgcg caacaccata tgttcttgcg
    23821 ccatgacacc tccgccaaaa acaatcactt gaggacggta aagcatagtt gcttgcagcg
    23881 ctgcttgggc aatgtagaag gcttgaatgt cccaaacatc agcttcctga tcaagccgtt
    23941 cacctctcac tcccgttctg gcctcaatac ttggacctgc tgccatccct tccagacacc
    24001 ctttatgaaa agggcaaaca cctaaaaacc ccttggccat atcatcagga tggggcatga
    24061 cataggtatg acccgcttct gtatgaccta atcccccaat aaagtggcca tgttgaatag
    24121 ctcccgcccc aataccagta cctatggtgt aatagaccaa actttccaca ccaggacgag
    24181 caagcacctc accataagca gagctattaa catctgttgt cacatcaaaa ggaatcttaa
    24241 aagcagccga aagttgtctt aacaaatcca cattagccca gcctgactta ggagtggttg
    24301 tgatgtaacc gtaagtctct gacgacggat caatatcaat tggtccaaaa gaaccaatag
    24361 caataccagc caaatctgcc tcaaaagctt taaaataagc gatggttcgc gcgatggttt
    24421 cttctggtgt ggtggtcgga aattgtgttt tatccaccac tgtaaactcc tcatcaccca
    24481 cggcacagac aaactttgtc ccaccagctt caatgcttcc atataagttt cccatgtttt
    24541 ctcctttttc ttgttctttt ttatctttat gatgacacag gctcttatca agacagccat
    24601 gtctcacgga caagcgccac tttctggtag tctaacgatt atttagcttt atgtcatcaa
    24661 aacctataaa agactaaaaa tctgggacta ttcatctcag atttttagtc ttttggttaa
    24721 tcaattccag caaaccttta tcatagtcac attttgttaa tttaatctga atgttgctat
    24781 ctaagagagt tactttgttt atttttttag cagctgcctt ttctcaatac aatctttcaa
    24841 aactccagca ttagcattaa tagcagttac atcaaaaatc ttactgttca aagaagtttc
    24901 taaagccatc tcttttattt ttaactcatc aagcatcttt tgagaaaact tatctttttg
    24961 ttgagacaac tctttagcag tagttactgt ttccatgata gtgtcggcgt taggtaacgg
    25021 ataacctaaa atttggagtt cagggagtga tggccaacta taatttcctc ccttagtatc
    25081 tacggttact ctccagtact tagcactaat attatccagt gcatggctaa atacctgttc
    25141 ttgtcctgaa taggttgaaa cagtttgcca atcatctgat ttttccaagc tcgttttcac
    25201 gtctgcttca gcattcagct ggcctgtaaa gacttcaagt tttgcttctt tgatataatc
    25261 ttttttatct ttactgctat cattgaaaag gcgccaatat tttgctaaac tagggtcttt
    25321 aatttcaaag ataatcgaag ctctattctg agtagatatc ggattatatt ccatgatgcc
    25381 attaaaaact tttttggcat tttcatcatt ttcactctta ataactgttg cgccttctgc
    25441 caaattaacc atcatggttt tttcgtcacc aacaatcact ttagcagtat gaacagcttt
    25501 tgtcttatct gctgggctaa agaagtcaac cttataggtc tcttctttat cagttgctag
    25561 cgttttgtca gtagtggttc ccaatgtgga atcagttact ttaacggtat agttctcata
    25621 agaaacttta aagttattgt aatgatagtt tgaatcaaca aagctacgtc cagcaatttt
    25681 atgattttgg taagccttat agtctgcttc gctattgatt agggttcctt gattcgtcac
    25741 agtcccaaac aaaagctggc tttgcaaatc aactttttca tttgccactg gtaagcgcag
    25801 actagttttc ccataggtat ctgggtaatg cccagttggt ttttgcttgt caaatttcac
    25861 tgtttgttca ttgcttccaa catgattgct gacagttgat agcatagtat caaaaatttg
    25921 tcgattttct gttcctggag ccaaatcaag tttgttgcca gaaatatcaa ctttttctaa
    25981 agacgttaga gtagcggcat caagaccagc caaggtttca cggtcaaaac ctgacaaatc
    26041 taattctttc agaccagtta aaccagaaac cttcaaagat actggtggga tagtagcagg
    26101 ttcttctttg ttatcttttt tataggtttc aagaactgtt tccaaggtat ctttgcctgg
    26161 cttcatatta gcgggtaaaa cagattggtc gagctttgta atgcgagata agccaatcaa
    26221 gtctaattga gctaattttt taaatttatt tagaccttct aaactttgaa tcgctggatt
    26281 atccaatcgt aatgtgccat tgaaacgttc caaatcacct tttctagttc caacctgcgc
    26341 catcacagct tctcgcaaag ccttatctgg gaaatctttc tcatcaatca gatcatacga
    26401 cttatctttt agcataactg tctttaatgc cttggagaca ctataatctg agtggaaaat
    26461 gttatcagta atttctggaa tctgaggctg attatttttt acattctgtt tatctttttc
    26521 agctatttgt ttgggttgat gagctacacc atcacggtca atagcgtagg agaagatacc
    26581 tcccttaacc ccacctgtct taggttgcca ccttgcatac cgttcggcac gcgttccagt
    26641 tatgtcagtg ttaattccat ttgctttgtc atcgtccttt cgagaattaa tatcatacca
    26701 aagattgccg ctgcctgctc tttcctcata gaaagaaaaa ccaatcatgt attgttcagg
    26761 acgaatatac ttgctataac cttgccatcg ttcttcaggg gtatcggtga ctaatttggt
    26821 atcattttga aagacacctt tctctccttg tgaaccatag atctgtacca gtaataaatt
    26881 aatataagga gctcctcgct caatcaatgg gtttttatca gccatatagg tgctatccat
    26941 aataaataac cgcgatttat caacaccttt tggtccaatt aatttcccaa tctcttcaaa
    27001 aacatcaata gatcgcttga ggttttcatc gttagctttc ccattcactt ttggaatact
    27061 atcatgttca acatccacat ctaagccatc aaggttgtat ttataaacat attcatcaac
    27121 aatagctttg gctaaagctt tatttccctc tggtgtattt gggtatttac tcgtatcttc
    27181 tgcaatacca ctgttatcac ctccagctag gaaacgccat ggaatggtac gaatgacacg
    27241 tgtcccttgc ttgtttaact ttggcacatg tttggtggcc aattctttcc aaaaaaggct
    27301 ataatctttt gtccaatcgt ggaaaataaa ggctagatct acttctttag gaagctctcc
    27361 catcgagtta actttgtctt tttctgttgg atctgatgtt ttgtcatgcc aagttctaaa
    27421 gtaaccaccg tagagaggac catgtaacgg tttcatcggt attttctcag gaattttcat
    27481 tttggtaagt tcttgagctt gtttatctgc ctgctgagct tttgctaata tctctttgac
    27541 cttttctggt actttttctt ttgaaagctc ctctttaaat tcttttttgc tattctctga
    27601 cagataatgc aagctatcga tagaagataa ttctttctga acctgaacag tcttctcctc
    27661 cgcttttaca gtattgagtg aatcatggtg ggtcgctaag gcagctccca tcaacgttgc
    27721 agcacaaaca caccctagtg ttctttttac caacaaatgt ttatccattt ggacactcct
    27781 tatttttggt actaagtcat ggcttcccag ttgatatacc atatatgtaa gcgcattcct
    27841 atagttcgtc ttaagtataa caacacttta ttaaaaaaaa caaggtacaa agtataggta
    27901 aaataacaca aatttaaggt ttttaggctt ttctcattat ttttgccaac ctgccattca
    27961 tggcaggaca aaagagctgc ttagtgagct cttttgtcct tatttgataa gtgccacttg
    28021 atcaccaatc aaaacatgtc cttgagcaag aatgtccacg ctttgatagt cagcgctatt
    28081 ggtcacaatc atcatggtgg tgtcatctag tccagcttgt gcaatcttgc taggatcaaa
    28141 gtgtccaaga agatcacctt ttttaactgc ctgacctact gctacaagag attcaaagcc
    28201 atctcctgcc atcgacacgg tatcaatacc aatatgaagt aacacttctg ctccttgact
    28261 tgacgttata gcataggcat gacctgtttc aaagacaatt tcaactttac catcaactgg
    28321 tgagtatagg gtattatctt ctggcttaat tgctaagcct tgacccatag cacctgatga
    28381 aaaaacaggg tctgaaaccg cagataagtc tacaactgtt ccattcaaag gactatataa
    28441 agtttcctct gctaaggctg gctgatcagc cgtttgatca acttcgacag ctggtaacgg
    28501 aaggggttct ctatcttgat aaccccaagt ataagcaatt ccaaaggcta ccccaagacc
    28561 gacaagcata gtcacaaggt attgtaataa ttggccattc aagtaaagga gagttcctgg
    28621 taagaccgta atcccaaaac cggttcctgc aatgccaaag agtccagcga cccaaccacc
    28681 taaggcacca ccaataagac ctgaaacaaa gacttttgga taacggaggt tgaccccaaa
    28741 aatagctggt tcagtaatcc ctaaaagagc tgacaaggtt gatggaaagg ccagaccttt
    28801 tagttttgtt gatttggttt taacagcaac agctaaggta gctccagctt gagcagctgt
    28861 tgctgctgtt aggtaagcat tgaaaggatc ttttccggta ttggcaatta gctgcgcttc
    28921 taggaagtta aagatatggt gaataccagt cactacgatc aactgttgga taccaccaac
    28981 aataagacca gcaatgccaa acggcaaatg caagacggcc tgtgtcccag ccagaacaag
    29041 gttttcaaga gaatggaaaa ctggtccaat cacaaatagt cccaaggtac tcataatagc
    29101 aaacgttaaa aacggtgtga ccaataagtc taaagcttct ggaacctttt tgtgcaacca
    29161 tttctccaac ttagctccta ccagaccaac aaagaaggcg ggtaaaacgg taccttgata
    29221 accaacaaca ggaacaaatc caaagaaggt tagcggctta acatctccac cagaggcaac
    29281 tatccaggcg tttggcaatt cattggacac cagcatcaag cctaaaacaa taccgataat
    29341 aggattaccc ccaaagaccc taaaggctga ccaagccacc aaagctggca agtagacaaa
    29401 ggctgtatcc gttagaatac gagtgtacat gagaaaattt tccccgtact catgcacccc
    29461 aaataaatcc ataatagctg gctgggtcac caaaccacga acccccataa agagacccgt
    29521 tgctacaata gctggaataa tgggaacaaa gacatctcca aacgtacgaa tcgcccgttg
    29581 gaagatattg ccttgtttgc ctgcttctgc cttttgctca ctggttgatg acgtgggtaa
    29641 accaagagca acgacttcgt cataaatgtt attgacggta ccagttccaa aaatcatttg
    29701 atattgacca gagttaaaga aagctccttt aaccttgtca atagcttctg ctttttcctt
    29761 atcaatcttt ccttcatcat aaaccatcac gcgaaggcga gttgcacagt gggcaacact
    29821 tctcacattt tctcgaccac ctaaagcctc aatcacttca gctgcaatct gacgattatc
    29881 catgcctaaa agtctccttt ttcatttggt gttagtccct cctccattct gccagctttg
    29941 tggctaagaa tgtgcaggac caacgctagt gaatccgctt cacttcttga ctatcatttt
    30001 atcactaata ttttttatgt caagcgttta acatattttt attttatatg ctttaaattc
    30061 ttgattttta aacagaaaac gtttagtata ttcttgaaga cgactataaa acaaggagat
    30121 tttgatggat ctaccacaag ctattcgcta ccgcccttac aaagagtgga gctcaaaaga
    30181 ctaccaagct attactgaaa aaatggccca atccccatgg cacagccaat ttcatgtcga
    30241 acctaagaca ggattactca atgaccccaa tgggttttct tatttcaacg gtcgctacca
    30301 tcttttttat caaaactggc cttatggggc tgcgcatggt ctgaaacaat gggtacacat
    30361 gacatccaca gacctcgtcc attttacgga aacaaggagc cgccttctgc cagaccacgc
    30421 tcacgatagt catggggctt actcaggttc tgcctatgct attgatgaca agctcttcct
    30481 cttttacact ggtaatgttc gcgatgccaa ttgggtcaga acaccattac aggttggcgc
    30541 atggatggat aaacaaggaa atatttccaa aataccacag gttttgattg aacagcccga
    30601 tgatgttaca gaacattttc gggatcctca gcttttttct tatcaaggtc aattctatgc
    30661 tattattggc gcccaaggtt tagatggcaa aggaaaaatc aaactttaca aagctgtgga
    30721 caatcatgtg gacaactggc gatttatagc cgatttggac tttgacgatt ctggtacgga
    30781 atacatgatt gaatgcccca accttgtgtt tgtcgatgac aagcctgttt tgattttcag
    30841 cccacaagga ctggctaaag ctgatttaga ttatcaaaat atctacccca atacctataa
    30901 aatttttgaa agcttcaatc cagaaactgg ccaattgctg ggtggggggg cccttcaaaa
    30961 tcttgacttt ggttttgaag cttatgccac tcaagccttt agtagtccag atggcagggt
    31021 tctagccgtg tcttggattg ggttaccaga tattgattat ccgacagatc gttatgacta
    31081 tcaaggagct cttagtttag tgaaagaatt aaggattaaa gacggaattc tctatcaaac
    31141 acctgtttca gccctacaaa atcttcgagg gccagcagaa ttatttcata ataaaataga
    31201 cagttctaac tgttatgaat tggaattgac gattccaggc caaaaaaagc ttgacctgct
    31261 cctatttgcc gaccaaaaag ggaatggcct aagattgaag gtggatacaa caaaaggaca
    31321 gttaagcatt gaccgaagtc gggcaggggt tcaatatgcc caagactatg gtacggtgcg
    31381 ctcttgccaa atcccacaag gccatgttac acttaatgtc tatgtggaca attccattct
    31441 tgaaatcttt attaaccaag ggcaaaaagt cctaactagt cgtgttttcc caacccaagg
    31501 acaaacaggt atccaagtag tagaaggaca agcttttgga cattattatg aaatgaggta
    31561 ttaggcaagt ggtcgcaaaa ttaacagacg tggcagcctt ggcgggtgtc agtccaacaa
    31621 ctgtttcgcg agtaatcaac aaaaaaggct acctttccca aaaaacagtg aataaggtga
    31681 ataaggccat gcgtgaattg ggctacaagc ctaacaatct cgctagaagt ttgcaaggta
    31741 aatcaaccca actcattggg cttatcttcc ccaacattag caatatcttt tacgctgaat
    31801 taattgaaca tttggaaatt gaattgttta aacagggcta caaaactatt atttgcaata
    31861 gtgaacataa tcccgtcaaa gaacgcgaat acttagaaat gcttgcggcc aatcaagtgg
    31921 acggcattat ttcttccagt cataatttgg gaattgagga ttatgagcgt gtcgaagctc
    31981 ctattgtagc ttttgaccgt aatctggcgc caaatatccc ggttatttct tcagataatt
    32041 ttgaaggtgg taaattagcc gcacaaactt tgcaaaaaca cggttgtcaa aacattgtca
    32101 tgattacagg taatgacaat tctgattcgc ccacagggtt gcgccagcta gggtttaact
    32161 accagctcaa acgaagtgca gaaatcatca aattaccaaa taacctatct cctgttagac
    32221 gcgaaatgga aattaaatcc attttggcaa cccgaaaacc tgatggcctt ttcgtttctg
    32281 atgatttaac tgctatcctc attatgaaag tagccaaaca acttcacatt actattccag
    32341 aggatatgaa agtcataggt tatgatggaa cgacatttat ccagcaatat gttcctcaat
    32401 tagcgaccat tcgtcaacct attgatgaga ttgctaaatt gagtgtcgaa atactcatca
    32461 aaaaaattaa aaaagaaaaa accagtaaag actatatttt accgattacg ctacttccag
    32521 gagcaagtat ttaaacaaaa cataaccaat cactaattac tctaaaagac aaacaagcat
    32581 actctttcta gatgcgagag tatgcttgtt tgtcttttaa tattcgtaca taaattgaaa
    32641 aaatcggata caatcctaag attgctccga cttattatga tttatttgct gaaggagctt
    32701 ccgagacata ttggctaagt aagccattaa taaatttagc agaggtttca tcagaatatt
    32761 ttttagctac ttcaatgatt tcgtttagtg caacacggtc tggtgtttcg tcaaaatact
    32821 tgatttcaaa aagacctagt cgtaataacg ttttgtctgt tagtgtcaag cgttctaacg
    32881 accaaccttt tttcaaatga gttgatatca agttatccaa ctcttcttta tgattattga
    32941 cacccgtcac aagacttaat aaaaaaatcg gcagctccaa tacttgagcg tcctcccctg
    33001 ttactttatc ataaccatag gcaaactgag aagctgccaa taactcagct cccatctcta
    33061 tgttaaataa agcctgaaag gcacgttcac gcaaatctct tcttgaattt tgaaagctgt
    33121 tagtcatcca agaaatcctc atcaaaaagt gacttcaaat ctggttttgg tgtcttttca
    33181 gcaacaatac cttcaacatg gatattaact gcagaaatag gcacttctgc catatcgtac
    33241 acagcagatt tgactgtttt ttgaatattc atagatacag tcgggacctt aactccatat
    33301 tgcaagtaaa cataaatatc tgctgtaaca cttccatctt cttctgtctg gagataaacc
    33361 cctttaccaa gacttgcttt attaaagcta tctgccattt tcttgttatg gagtgagtgg
    33421 acgccctcaa cttgtgtcgt agcaatcccc gtaataacct caagtactcg tggtgaaatg
    33481 acgatttcac cgatatattc agttgtcata gcatttcctt tctctttttt agactaatct
    33541 gttttgacaa aggattaagc acgagaaacg taagtacctt ctgcagtgtt aatgattagt
    33601 ttttggccag cttcgataaa gtctggaacg ttaacaacaa gtcctgtctc aagagttgca
    33661 ggtttccctg aacccgtcac tgtcgctcct ttaatagatg gttgtgtttc cgcaacggtc
    33721 aattcaacag ttgttggaac cgttacccca atcacttcac ttccataaaa ttggattttc
    33781 acgtctgagt tttcaagaat gtaaagcaat tcttgctcaa cgttagcaac tggaatttcg
    33841 tactgatcat aagtgtcagt gttcatgaag taagcagtgt catccatttt gtataggtat
    33901 tgtgctggga cagtttcaat gatggcttgc tcaaattttt catctgggcg gtaagttgtg
    33961 tcaaaagtag aacctgtacg cacatcacgt agtttcatac gcatgatagt gtttccttta
    34021 cctggtttgt ggtggctagc ttcaaggaca cggattaatt ttccttctgc ttcaaatgtc
    34081 atacctgctt taagcttact tgcttcaatc attattatta cctcttacta aaatatttat
    34141 cacttcattt taccacaaaa gtggccttgg ctcaaatctt ttatgaccgt ccttttaggt
    34201 acactttcta ttgttcctta tcgcctccta aaacaatttg aggcacatca tgttgcacat
    34261 aggcaacccc ttttttctcc atcagttcaa tggcaaaggg gtgcggacgg taatgtgctt
    34321 tataggtaat ctttgtaatc cccgcctgca aaagcgcctt agtgcagtta atacaaggaa
    34381 aatgagtcac gtaaatttca gttccgtccg ttgaaattcc ttctttcgca cattgaatca
    34441 aagcattcat ttcagcatga acagtgcgaa tacaatgtcc gtcttccata taatgacccg
    34501 cttcgttgca gttatccgta gcagaaactc cgccattgta acctgtggca ataatgcggt
    34561 tatcctttac caaaacagct cccacaaagg cgcgatcaca ggtagagcgc ttggaaatca
    34621 gctctgcatt ggccataaaa tagtcttgcc atgataaacg atttgtcatt gcttctcccc
    34681 taatcctttc ctgaaccatt cttttacaat acaattaatt ctttgggtgc caaggtcaag
    34741 acttgacaac cagtttttgt gataaccaag tcatcttcaa tacggacacc atatttgtta
    34801 tccaaataga tacctggctc atctgttacc accattccag cttggagaag ttgctcagat
    34861 ttcccaaaaa atggattctc atggatgtca agcccgatgc catgaccaat gccatgtgtg
    34921 aagcgactgc cataacccgc ctcagtgatg agttggcgcg gaataccgtc aaagtcacta
    34981 taagtcatgc cagcgctagc tttagcaatt aaagccttat tagcagcaag aacaagagca
    35041 taaatctcac gttcttcatc agtaacttgg ccaatatgaa tggtcctcgt catatcacta
    35101 acatagtgat tgtagtaaca cccaaagtcc atggtcaagc tctctttatt ctggataacc
    35161 ttgtcactgg cgcgtccatg aggcatggca gagcgatagc ctgaagctac aatgatatca
    35221 aatgatgtgc cgctggcacc atactgacgc atacgaaaat ctaaaaaatt agccaggtca
    35281 cgttcagtgg ttgtccctgg tttaataaaa tcaagagcat cttcaaatgc tttgtctgag
    35341 atcgagcacg ctttagcaat ggtatcaatt tcagaagtat ccttaataaa acgtaaatgc
    35401 tccacaaaac ctgactgagc aagcaaggtt attcctgaca gttctgcttg catggcctga
    35461 taaaaagaaa acgatacctg gtcctcaaaa ccaaggcaat ctatttgatc agcctctaac
    35521 aattctgcca caaccttaag cggcgtgcgg ctttcgataa tatcaaatcc ctcaacacta
    35581 gctttagcaa gcaaggtata acgtgaatct gtgatcaaaa cacgacgttt ggccgttatc
    35641 aaaacagttg ctgcagttcc agaaaaacct gtcaagtaat aactattggt taaatgggtg
    35701 actagaagag cctctagccc cttctctgcc atctgcctta ggcagtgacc taatcgttgc
    35761 tctaaaaatc ctgacatcgc gaactccttt ggtaactttt gagaatattg tagcatgaaa
    35821 aaactacttt aagtttacca tgatttgaga gcatttaaaa gattaaaaag gagctcaaac
    35881 gaactcctaa tcctattgtt gtagttttac tttcaaataa tgaccagtat agctttcttt
    35941 aacttgagct acctcttctg gtgtccccgt ggcaacaatc tgaccacctc cgacaccacc
    36001 ttctggtcct aagtcaataa tatggtcagc agatttgata acgtccaaat tatgctcaat
    36061 cacaagaacc gtattaccat cgtctacaaa gcgttccaaa acttttaata gccttgcaat
    36121 atcatctgtg tgtaaaccag tcgttggctc atctaggata tacaagctct tacctgtcga
    36181 gcgtttgtgc aattcactag ctaatttcat ccgctgcgct tctcctccag atagagtagt
    36241 agctggttga cccaaggtca cataacccaa accaacatcc ttaatggttt gaatttttcg
    36301 ggcaatttta gggatagcag agaaaaatac caaggcatca tcgacagtca tgtcaagcac
    36361 ttcagcaata tttttttctt tataatgcac ctcaagcgtc tcagaattat accgtctgcc
    36421 gtggcaaacc tcacaaggca cataaacatc tggcaaaaag tgcatttcga ttttgataat
    36481 cccatcacct gaacaagcct cacaacgccc acctttgaca ttaaaagaga aacggccttt
    36541 tttgtagcca cgaatcttag cttcgttggt ttgggcaaac aagtctcgaa tatcatcaaa
    36601 gacacccgta taggtggctg gatttgaccg tggcgtcctt ccaatcggac tttggtcaat
    36661 gtcaatcaag cgttcaatat gttcaatacc agaaatagag tgatatttac caggcttatc
    36721 agcattacgg tttaattttt gggcgacagc ctttttcaaa atactattaa ccaaggttga
    36781 tttccctgag cctgataccc ctgtgacagc aataaatttg ccgagaggga atctaacatc
    36841 aaggtgttga agattgttct gcgctgctcc ttttatttca atgaatcgcc cattaccaga
    36901 acgacgctct aatggcactg gaatgaattt tttaccagac aaatattgac ccgtgatgga
    36961 ttttttattc ttagccactt gtttcggcgt tccagaggca gtaatttctc caccgaactc
    37021 acctgccccc ggtcccacat caatcagcca gtctgcctgc atcatggtgt cttcatcgtg
    37081 ttctaccaca attaaggtat tacccaaatc acgcattttt ttcaggcttt cgatcaaacg
    37141 gtcattgtct ctttggtgca atccaataga aggctcatcc aagatataga gcacccctga
    37201 taagttagaa ccaatttgtg ttgctaacct gattcgttga ctttccccac ctgataaagt
    37261 cccagcagca cgtgataagg tcagataatt cagtcccaca ttatttaaga atgtcagacg
    37321 gtcatggatt tctttgacaa tcggtttagc aatggtactt tcattttctg tgagttccaa
    37381 ttcttccaac aactgcaagt ggtcggcaat cgataattct gaaatttgac caatatgagg
    37441 tccttcttcg ccacccacat gcacacacaa agcttggtca ttcaaacggt aaccatgaca
    37501 agtcgcacag gtcaattcgt tcatataacc acgcatcaca ttgcgcgtat aatcactatt
    37561 agtttcgtga taacggcgat taacattagt cacaacacct tcaaaaggaa tgtcaatgtt
    37621 acgctcacca ccaaaatcat tcacatagtg aaaatgaaat tctctatcac ctgaaccata
    37681 aagcactaaa tctctttctt cctcagtcaa ggcctcaaaa ggtgtatcca tatccacccc
    37741 aaaacttgcc atagcttgct caagcatggt tgggtaataa ttggaggaaa taggattcca
    37801 aggcgccaaa gctccctctc tcaaagactt acttgggtca ggaacaacca agtccaaatc
    37861 cacttccaac ttaatgccta gcccatcaca ggtcggacaa gagccgaacg gcgcattaaa
    37921 agagaagagt cttggttcta attcaggaac cgtaaatcca cagacaggac aggaataatg
    37981 ctcagaaaag agcagttcat tgccatccat agtgtcaatc ataaggtagc catctcccag
    38041 ccttaaagct gcttcaaccg aatcaaataa acggctacga ataccatcct tattaaccag
    38101 acggtcaata accacctcaa tgttgtgcat cttacttttg gacaactctg gcacttctgt
    38161 cacgtcaaaa atatccccgt caacgcgcac acggacatag ccgtcttttt gaattttctc
    38221 aaaaactgtt ttgtgttgcc ccttcttccg acgaacaaca ggagctaaaa tctgcatgcg
    38281 tgtccgttca gggagggcta agacctgctc tacaatttgt tctgcagaag acgccgtgat
    38341 agcaccatgc ccattgatac agtaaggtgt gcccacacgc gcatatagta gacgtaaata
    38401 atcattgatt tccgtaaccg taccaaccgt tgagcgaggg ttcttactgg tggttttttg
    38461 gtcaatggaa atagcagggc taagaccgtc aatggaatcc acatctggtt tttccatatt
    38521 acccaagaac tgtctagcat aagctgataa actttctacg taacgacgtt gcccttccgc
    38581 ataaatagta tcaaaggcta gactagattt tcctgaccct gataaccctg tcacaacaac
    38641 taatttgtct cgtggaattt ccacgtcaat attttttaaa ttgtgggctt ttgccccatg
    38701 aattattatt ttattttgca tcttgaatgt gcctaaaggc accctcctca tcgagctttc
    38761 ttatattata acaaaaattt ctgataacct attgccccaa actttgcgaa ttttggtata
    38821 atagataagt attgagaatt tttcagaaaa tccttgagaa ggctttatta tcaaggtttg
    38881 atgtcaatct ctaccagtca atcatcaaaa aggagggctt gtcatgaaac aaatgtttct
    38941 ttcatcggca attgaattca aagaaataga aacattcgag ccaggagctt ggattaaact
    39001 ggttaaccct tcccaagaag agtctatgaa gatcgccgat caatttaaca ttgatatttc
    39061 tgacttgcgc gcccctttgg acgtggaaga aacctcacgt attgccgtag aagatgatta
    39121 taccctaatt atcgtagacg ttccgatata cgaagaacgt aacaataaaa gttactatat
    39181 tactatgcct ttaggcatta ttgtaacgga aaatgctgtt atcacaactt gtctgcatga
    39241 catgaccctt ttcgatcatt ttcacaaccg ccgggtcaaa aatttctata ccttcatgaa
    39301 gacacgtttt gtttttcaga ttctatatcg caacgccgag ctctttctga ctgccttgag
    39361 gaccattgat cgccaaagcg aacgtttgga agctcagctt gaagcagcta ctcgaaatga
    39421 agaacttatc gacatgatgg aacttgaaaa atccattgtc tacttaaagg cttccttgaa
    39481 attcaacgaa cgcatcgtca agaaattatc cagctcaaca agctctctca agaaatacat
    39541 tgaggacgag gatttgctag aagatacctt gattgaaacc caacaggcca ttgagatggc
    39601 tggcatttat gaaaatgtct tgaatgccat gactgaaacc actgcttcta ttatcaacaa
    39661 caaccagaac actattatga aaacactggc cttgatgacc atggctttag atataccaac
    39721 tgtgattttc tccgcctatg gtatgaattt ccaaaacaac tggttaccac taaatggcct
    39781 agaacatgct ttttggtata ttaccttgat tgctatgcta cttagttcct ttgttgtgat
    39841 ttactttatt agaaaaaaat ggttctagag tggagcaagc tgcagaatgc gtttaacacc
    39901 tgacaaaact ctgtgtcaaa cggctagctc caaagtttca ttacaactag ctaataccat
    39961 tgacttactt taactaaccc atataaagaa gggattccca tggaattaca agaacttacc
    40021 aaaaaaaatc aagaatttat ccacaccgct acgaacaaat taatccaaga cggcaagtct
    40081 gatgaggata ttaagctgat tctcgaagaa gccattccag ctattctaga aaaccagaaa
    40141 aaaggtgtca ccgctcgaaa tctattaggc actccgactg cttgggcagc ttcttttagc
    40201 caagacccta gtcaaagagc agcagaaact gacaaaaaca ccaatccttt gttgatgtgg
    40261 ctagatacct ctttactatt catcggaatt gttgcccttt taaatggcat catgaccttc
    40321 ttcaacacaa acgctacagt tacaggattg atttccttac tggcacttgg ttttggtgga
    40381 ggagcatcca tgtacgctac ttattacttt atttaccgtc atctcggaaa agataagagc
    40441 cttcgtccaa gttggttcaa aatcatcgca gccttatcat tagccatgtt gatttggatt
    40501 gccttgtact ctgcaactgc ctttttacca acctctctta acccacagtt gcctcctctt
    40561 gccttgctca ttattggtgg tgtttccctt gctttacgct attacctaca acgcaaatac
    40621 aacattcaaa acactatgtc acctgttaac aaataacaat catttcatcc ttgctgtcta
    40681 cgcaaggatt ttcgtttact atcattctct cttttagaaa aaactcacct atacgcctag
    40741 actagtccta gtcaactaaa aaacagtccg aaatggactg tttgtttatt agtcttcgtt
    40801 tacgtaaggc ataagagcca taacgcgagc acgtttgatt gctgttgtta ctttacgttg
    40861 gtttttagct gaagttcctg ttacacgacg aggaagaatt tttccacgtt ctgaaacgaa
    40921 acggctaaga agctcagtat ctttgtaatc aacatattca attttgttag ctgcgatgaa
    40981 gtcaactttt ttacggcgtt tgaatccgcc acgacgttgt tgagccatgt attttctcct
    41041 ttataaatta tgatgttaag ggctcttaaa aaacgactga attttagaaa actggcaaga
    41101 aatcttgatt tcctagggag ttgatctaaa ttctaagttc taaattttta gcccgaactc
    41161 aaataatttc gtattcgttc aatccattct gactagaatg gaagatcgtc atctgagata
    41221 tccatcgggt ttgagttccc aaatgggcta tcatctcttc caaagttagg cgtttgttgt
    41281 gcaggcgctg agtaactgtt tgatgatgaa gtgttattgt taaaaccacc attaaatgag
    41341 ccagttgagc caccttcacg tgtagcacga ctttccaaca tttggaaatt atctgcaaca
    41401 acttctgtta catagacacg ttgtccttgt tggttttcgt agttacgtgt ctgaatacga
    41461 cccgtaactc cgatcaaggc acctttttta gcccagttcg ctaaattttc agccggttga
    41521 cgccagatca cacagttaat gaaatctgcc tcgcgttcac cattttggct tttaaaggta
    41581 cggttaacag caagtgtgaa ggtagccaca gctacttgac ttggtgtgta acgaagttct
    41641 gcatccttgg tcatacgacc aactagtact acattattaa tcataaacta ccctcttagt
    41701 tggaattaag cgtcaagttt aacgatcatg tgacgaagaa tgtcaccatt gatttttgaa
    41761 agacggtcaa actcgttaag agctgctgcg tcagtcgctt caaggttaac gatgtggtaa
    41821 agtccttcac ggaaatcgtt gatttcgtat gcaagacgac gtttttccca atcttttgat
    41881 tcaacaacag ttgcaccgtt gtcagtcaag atagagtcaa agcgtgctac caaagcgttt
    41941 ttagcttctt cttcaatgtt tggacgaatg atataaagaa tttcgtattt agccattgat
    42001 attttcctcc ttttggtcta atgactcact acttttggag tgagtaagtg aggtatactc
    42061 acagaatctt attgtacact aatagtcaat taaaagcaag gaactttttc tacttgacta
    42121 agttttgtca aacattttct ttcacgagtt ttaaaaattg gcacttagtc agactcctaa
    42181 aaaataggtg aaaaaagaaa aagcaaggaa aagttttaac caaagtgcaa aatataaaat
    42241 tagggccaaa acaaaaaggt taaacttttt aaaaataata gcaaccatgg cacatacgat
    42301 acctaatcca ggaaaaactt gcgtcatgat cagccattcc aactgtagtc cgctcaaaga
    42361 aggatcaaat ggataaatat agttaagaaa taacacaaga atcatcatta taaaaacgaa
    42421 ccacgaatac cgatcaataa gattctttaa tttctggaac atgtcccctc caaattaaaa
    42481 cctgtctgct tctatcgtta atttcagtta ttctaaatca acatttaga
//
LOCUS       DAUNLR010000011        42190 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUNLR010000011 DAUNLR010000000
VERSION     DAUNLR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42190
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.011"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..672
                     /locus_tag="VLL59_000558"
     CDS             <1..672
                     /locus_tag="VLL59_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HER6508705.1"
                     /translation="KAYRPGEGVKARKEAAKANLEKVAKETKALISGDRYLSETEKAV
                     QKQAVEQALAKALDQVEAAKTVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAALNEA
                     KQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIASVK
                     EAKDKGITAIRAAYVPNKAVAKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLYSKK
                     KESKD"
     gene            complement(858..974)
                     /locus_tag="VLL59_000559"
                     /pseudo
     CDS             complement(858..974)
                     /locus_tag="VLL59_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611996.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1537..1698
                     /gene="sagA"
                     /locus_tag="VLL59_000560"
     CDS             1537..1698
                     /gene="sagA"
                     /locus_tag="VLL59_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HER6508706.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            1920..2870
                     /gene="sagB"
                     /locus_tag="VLL59_000561"
     CDS             1920..2870
                     /gene="sagB"
                     /locus_tag="VLL59_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HER6508707.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            2867..3925
                     /locus_tag="VLL59_000562"
     CDS             2867..3925
                     /locus_tag="VLL59_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HER6508708.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENALEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNDPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            3945..5303
                     /locus_tag="VLL59_000563"
     CDS             3945..5303
                     /locus_tag="VLL59_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HER6508709.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            5278..5949
                     /locus_tag="VLL59_000564"
     CDS             5278..5949
                     /locus_tag="VLL59_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HER6508710.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWYLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKKVT"
     gene            5946..6629
                     /locus_tag="VLL59_000565"
     CDS             5946..6629
                     /locus_tag="VLL59_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HER6508711.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLVALSYQDFLDV
                     LLSLFQFVIIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            6652..7575
                     /locus_tag="VLL59_000566"
     CDS             6652..7575
                     /locus_tag="VLL59_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508712.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            7584..8711
                     /locus_tag="VLL59_000567"
     CDS             7584..8711
                     /locus_tag="VLL59_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508713.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILSLIGMRKQVTT"
     gene            8708..9826
                     /locus_tag="VLL59_000568"
     CDS             8708..9826
                     /locus_tag="VLL59_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508714.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGETLSQAWPYLLALMGTALALISFSSLLLKPTKL"
     gene            10397..13129
                     /locus_tag="VLL59_000569"
     CDS             10397..13129
                     /locus_tag="VLL59_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HER6508715.1"
                     /translation="MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPEKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      13294..13409
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            13407..13907
                     /locus_tag="VLL59_000570"
     CDS             13407..13907
                     /locus_tag="VLL59_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HER6508716.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            14101..16059
                     /gene="ligA"
                     /locus_tag="VLL59_000571"
     CDS             14101..16059
                     /gene="ligA"
                     /locus_tag="VLL59_000571"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HER6508717.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELAGLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKENFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            16073..17095
                     /locus_tag="VLL59_000572"
     CDS             16073..17095
                     /locus_tag="VLL59_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HER6508718.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDEALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            17487..17684
                     /locus_tag="VLL59_000573"
     CDS             17487..17684
                     /locus_tag="VLL59_000573"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HER6508719.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            17719..18435
                     /gene="atpB"
                     /locus_tag="VLL59_000574"
     CDS             17719..18435
                     /gene="atpB"
                     /locus_tag="VLL59_000574"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HER6508720.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            18453..18947
                     /gene="atpF"
                     /locus_tag="VLL59_000575"
     CDS             18453..18947
                     /gene="atpF"
                     /locus_tag="VLL59_000575"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HER6508721.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            18947..19483
                     /locus_tag="VLL59_000576"
     CDS             18947..19483
                     /locus_tag="VLL59_000576"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HER6508722.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            19499..21007
                     /locus_tag="VLL59_000577"
     CDS             19499..21007
                     /locus_tag="VLL59_000577"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HER6508723.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            21023..21898
                     /locus_tag="VLL59_000578"
     CDS             21023..21898
                     /locus_tag="VLL59_000578"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HER6508724.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMCMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            22060..23466
                     /gene="atpD"
                     /locus_tag="VLL59_000579"
     CDS             22060..23466
                     /gene="atpD"
                     /locus_tag="VLL59_000579"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HER6508725.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            23479..23895
                     /locus_tag="VLL59_000580"
     CDS             23479..23895
                     /locus_tag="VLL59_000580"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HER6508726.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            24161..24418
                     /locus_tag="VLL59_000581"
     CDS             24161..24418
                     /locus_tag="VLL59_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HER6508727.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFC"
     gene            24483..25754
                     /gene="murA"
                     /locus_tag="VLL59_000582"
     CDS             24483..25754
                     /gene="murA"
                     /locus_tag="VLL59_000582"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HER6508728.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            25758..25946
                     /locus_tag="VLL59_000583"
     CDS             25758..25946
                     /locus_tag="VLL59_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HER6508729.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            25982..26521
                     /locus_tag="VLL59_000584"
     CDS             25982..26521
                     /locus_tag="VLL59_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HER6508730.1"
                     /translation="MLTRKKRKRVQEQKVPKRANALLTKSTRQYQDRSQLKKGYRSFK
                     PAGWHRLHHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKP
                     YSTGQNYYEGLVRRALDKGHRVRYRVTLLYDGDNLLASGSHLKAKSSDDSLAFNVFVP
                     NVQAGLTVDYRTGQIAINL"
     gene            26804..27847
                     /gene="pheS"
                     /locus_tag="VLL59_000585"
     CDS             26804..27847
                     /gene="pheS"
                     /locus_tag="VLL59_000585"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HER6508731.1"
                     /translation="MDLQAQLEELKSKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            28057..30462
                     /locus_tag="VLL59_000586"
     CDS             28057..30462
                     /locus_tag="VLL59_000586"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HER6508732.1"
                     /translation="MLVSYKWLKELVDIDVTPVALAEKMSTTGIEVEGIEVPAEGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIELSIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDGNS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTSIKLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            30572..30949
                     /locus_tag="VLL59_000587"
     CDS             30572..30949
                     /locus_tag="VLL59_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HER6508733.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTVAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            30942..31328
                     /locus_tag="VLL59_000588"
     CDS             30942..31328
                     /locus_tag="VLL59_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HER6508734.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKKHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            31401..32477
                     /locus_tag="VLL59_000589"
     CDS             31401..32477
                     /locus_tag="VLL59_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508735.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GIGNITIAQAVLLQTFLLSALGSGLGLLGTWLTSLVLPEAVPFQSNWLVYLAILVSMV
                     CFALLGTLFSVFSIVRIDPLKAIG"
     gene            32487..33155
                     /locus_tag="VLL59_000590"
     CDS             32487..33155
                     /locus_tag="VLL59_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508736.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKVTDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGIAGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYRMQDGEL
                     RQER"
     gene            complement(33259..34176)
                     /locus_tag="VLL59_000591"
     CDS             complement(33259..34176)
                     /locus_tag="VLL59_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HER6508737.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDNTLQEETYGRAVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            34327..37542
                     /gene="rexB"
                     /locus_tag="VLL59_000592"
     CDS             34327..37542
                     /gene="rexB"
                     /locus_tag="VLL59_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HER6508738.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDYPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLIDKLILFLEKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            37503..41171
                     /gene="addA"
                     /locus_tag="VLL59_000593"
     CDS             37503..41171
                     /gene="addA"
                     /locus_tag="VLL59_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HER6508739.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDITHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKTEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYCFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDIRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            41311..42123
                     /locus_tag="VLL59_000594"
     CDS             41311..42123
                     /locus_tag="VLL59_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HER6508740.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHHERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLSGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLETPVAAGFLAQHKDLTLAPFSL
                     KTSGGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
BASE COUNT        13269 a         7129 c         8603 g        13189 t
ORIGIN      
        1 aaagcttacc gtccaggtga aggtgttaaa gcacgtaaag aagctgctaa agctaatctt
       61 gaaaaagtag ctaaagaaac taaagctctt atttcaggag accgttactt gagcgaaact
      121 gaaaaagcag tccaaaaaca agctgttgag caagctcttg cgaaagcact tgatcaagtt
      181 gaggctgcta agacagttga agctgttaag ttggcagaaa accttggtac tgtagctatc
      241 cgttcagcat atgttgctgg tttagctaaa gatactgatc aagcaacagc tgctcttaac
      301 gaagcgaaac aagctgctat tgaagctctt aaacaagctg cggcagaaac acttgctaag
      361 attacaactg atgctaaatt gactgaagct caaaaagctg aacaatcaga aaatgtatca
      421 ttagcgctta agacggctat tgcgactgtt cgttcagcac aatctattgc gtctgtgaaa
      481 gaagcaaaag ataaaggtat tactgctatc cgtgcagcct atgtgcctaa taaggcagtc
      541 gcaaaatcat cgtcagcgaa ccatcttcca aaatcaggtg atgcaaactc aattgttctt
      601 gttggcttag gagttatgtc tcttctttta ggtatggtgc tttatagcaa gaaaaaagaa
      661 agtaaagact aagaacctgg ctttatccaa attgctttct actatatttt caaaccaagg
      721 tgattttgaa atcaccttgg ttttttggat cgtaagggct caagaacgga gtgtattgaa
      781 aacatttcaa agttcaattg aaaaggcaac agttttctgt acagaattta taaggcgttt
      841 tttgttcaaa cgatgactca tttagttata ggtgtttgat aattaagatt actgtgaagg
      901 tgatggtagt tccaccagtg gacttcctcc ttggttttaa gggttaattg ttctagtgaa
      961 taaaaggttt cttggttgcg cagtagggat caagcgagca gataaaatgc ctattttaaa
     1021 tcagttcgag cgaattttcg tgctacaagc tcaaaagagg ctactaaagt attagaacag
     1081 tttatctctg agtgaagttc ttgttataag aagatgatgt tatcgtttga aacgaccaaa
     1141 aaatctccta acttttacta atttctacat gaaatctagt ccagtattta ctctacaacc
     1201 ttgattgatt cgcttaataa agacatttct acttgattgt ttacacatag ttattgatag
     1261 aatctattat aaaattcagt atattagatc ataattgttt ctatattaat caattattat
     1321 tttttttgtc atttttgata atattaaaaa gaaagggttt acatattaat cattttttac
     1381 tataataaaa gtgataagaa ctagatagtt gttgtgttac aacagtacaa ttgagctagc
     1441 cttgtccttg ttgtgttaac tttattttta aaataaggtt aaaaataaac aactcgtgtt
     1501 cttatcagtt acttattaga taaggaggta aaccttatgt taaaatttac ttcaaatatt
     1561 ttagctacta gtgtagctga aacaactcaa gttgctcctg gaggctgctg ttgctgctgt
     1621 actacttgtt gcttctcaat tgctactgga agtggtaatt ctcaaggtgg tagcggaagt
     1681 tatacgccag gtaaataatc tatttagcat ctctatgtga tagtgatatt aaggtaatga
     1741 gtttgctagc aactaagtta tctttggtaa cttctgatta tagatgaatg gcatagaggt
     1801 attagaaaac atgagacaaa agtaatcttc ttgatgctaa cgtctcaggt aattagcagg
     1861 tactagacag tacctgctaa ttactatatg tttagtaaaa tgagatagga aagatagtta
     1921 tgtcattttt tacaaaggaa caacaaccta aagagaattg tccgccaata actgttgaaa
     1981 aagcaaggca attgtttgaa tttaatacaa accacttgtc cttatcggat taccatcatc
     2041 aaacggtgct aaaaacgtca aagcagctag ttgctcaaca tttaatgcct aatgcaaccg
     2101 ataatcttag tcaacatttt ttgatgaact ataaagctaa taataattat ttaggcttcc
     2161 aagctagtat tgtcgacttt tttacagatt ctgccgttgc taatttttca agtagttacg
     2221 tttatgaaag tcaggaaaag ataattcgtt taccaaaacc taccaagata tcaactgctc
     2281 tgtcgacatg tattataaaa cgaagaagtc atcgtcaatt ttcagataga caaatgcctc
     2341 ttcaagattt atcaaacatt ctttattatg catgtggtgt tagttcacaa gcatcaatta
     2401 gagatggagc atcagataag attacactca gaaactgtgc ttcaggtgga ggtttatacc
     2461 ctattcattt agttttttat gctagaaaca tcagtaaatt aatagatggt ttctatgaat
     2521 atctacccta tcagcatgca ctaaggtgtt atcggcatag ctctgaggaa aacgttagag
     2581 attttgcgga atacggtgct attaatgctg aaaattgtaa tattattatt atttatgtct
     2641 accattacat gaaaaataca cgtaaatatg ggaatcaggc gactgcctat gcttttattg
     2701 aatcaggaga aatagcccag aatattcaat tgactgcaac tgccttaact tatggaagta
     2761 ttgatattgg tggttataat aaggaatatc tccaagaatt attagattta gatgggctag
     2821 gagagcatgt gattcacatg acactcgtag gaactaagga gtctcaatga aatatcaact
     2881 taatagtaat gttcgtgtcg tgacatttca agatacattt tgttttagaa aaggaatctg
     2941 ggactttaat gaagccattc tagatttgac acaagaacct caaaatttaa agatagttta
     3001 tcaagaaata gtttcacagt tggttaaggg agtagccatt gatactgaaa cttatgaaaa
     3061 tgctttagaa cctgagacgt tcgctaattt aatggaagtc atttcaggct tgtattacaa
     3121 tgatatgctg atgcttgagg atgactacaa tcttgaagaa aatgtcatga aaattttaat
     3181 gggtaatttc cgttttatgg cgcaagcagg tcatatggta agcaatgatc ctgttttgtt
     3241 tatcagtgat tcgacttatg ttaatgaatc tgctgagttg ctagctgaac aactgcattt
     3301 acaattgcaa gtggctagcg atgacttaaa aatgttaatt cagcagacag atgttagttc
     3361 gcgtttagat gctttggagc atcgccgtaa catgaattgt ttatcagaag ccttgtgcga
     3421 ttaccaaagt attattattt gtcaagaacg cttgaatatt atgatgttgc gacacttgaa
     3481 tgaagttagc gtagctatga aaaaacaatt agtgattggt tttgtagatg gaccattctt
     3541 gcacacttgt actttgaatc ctcctcatag tgctgacttt gatagcttag aaagaagagt
     3601 tttggcacgt ttacaagact caactctcta tcaacatttt gctaatcaga ttttaccagc
     3661 aacacaagat gtgagccagg cctatttacc attgttaaat gttttaatga atttagtcgt
     3721 tagcgaagct ttcattattg ctcaaacagg tagttctaaa tttgagggac gtttattaag
     3781 catttactta ccgacgcttg agattcaggt ccaagatatt ttgaaaatgt ctaattcaca
     3841 gacacaagga gctttggcaa aattaaaata tgaggatcag cagatatcaa cacgtgagat
     3901 tgttaaaaaa ctccttgacg agtaacctat aaggagaatc tattatgtta tactattatc
     3961 cttcttttaa tcatattttt gatgaattaa aaagtttaag tggcaatcga acaggtatct
     4021 taaatcaatc tcaagttcca gtttgcaacc atcctcacga tgtttactta aaaagtatta
     4081 ctggccaaat gccagattat cataaacaat ttataggtga gttgagtcaa gttagttatc
     4141 acattattgg ttacggcagt tactatgaag aagcacttat caagtattta ggagaaagta
     4201 ttgaacgcta tgctactgta attgccggag acttactatc agatcggatt gtctatgctt
     4261 cttataatga gttaaaactg ttacataaag tgatgccttt agaatacttg caagtgttta
     4321 ctcaagaaca gatcgcatta tcttgtgact tgcaaatgat gatgtgcgat aaaatggtaa
     4381 ctgagaacga tgtattgggc tgggttaaat gtcccatgtt ctttgaggac gcagagatgt
     4441 atgttccagc tcaaatgctt tgtgttgggt ataaaacaaa tgagactgta ggagaaagac
     4501 ggataatacc aggattttct acgggaacag cttctcacaa aacgttagaa gcggctatgt
     4561 gcaacagttt gattgaatac atccagatcg attcaatgat gcttagctgg tatactaaga
     4621 agccttgccc caagattatt gttgatgatc ctgatattga agtgatttta gaagaagcta
     4681 gactgggaaa agacagtcta tacgacatta ttcctatcga tatgactgta ggagaagata
     4741 atcctcttta tacgtttgga atcattctca aaaataaata tgatgaaggg ccttacctct
     4801 tgtttggagt gcaggctggg ttagatccta aacatgcttt gctaagaggg atcatggaag
     4861 cttcagctat cagctatagt tactactata atcttttata tcaaaaagct tcccttgcaa
     4921 atattgaatg cgaagaacct ttgtttttag atttagatag taatgttttc tattatgcac
     4981 atcccaagga ccaagaccat aaatggaagg cctttgaacc tttgatttca ggagaagttc
     5041 tgttaagtga tttggaagat cattctggta aagataaaaa agaagatttg aagactttat
     5101 tagcttatgc taagaaagtc agtcctaatg ctgtcttttt agatattaca cctcctgaag
     5161 ctctagaaaa aggctggtac gtcacgcgag ttctgatgcc agaacttctt gaaatgtgta
     5221 taccagcatt tccttttgct aatcacccac gaatgagaca gtttggaggt gtaacaaatg
     5281 cctttgtcca tccaatgcct taatctttgt tttttgttgg taactttttg tccttcaatt
     5341 cctatgcaag ctatttttgg aaaagaagat agtggttatg catttaattt aattggtttt
     5401 ctaagagcaa ctctgattta tgacattttg gctttggtaa gtatttatgt tttgtcacct
     5461 caaataacct tgtctcttga aagtattgat agtaagacgt tctttatggg acttgtattt
     5521 tgcgtcttga tagtactgat tgaactcgtt ttcttacatg gtttacgttg ttggcaaaaa
     5581 aagcaatggc ttcctgcaac tttctcgttt gtaggaacga caaatgattg gtctaagatt
     5641 ggctatcctt tattactagc tttatttgaa gagacgattt atcgtttttt gtggtttaat
     5701 atattagctt ttcaatggta tttaccaaca attattgttt taattgtaac tagtttttgc
     5761 tatgctttaa atcacttatt gatggggaaa tccatttttt atgctaagtt ggtaacaggc
     5821 atcatttatg gtagtattta catgctgact agtcaattgt ggttggttgt gataatgcat
     5881 gtaggaggga acttgctagt tgagtgtctt agccatcttc aaacaaaaaa gaagaagaag
     5941 gtgacatgat gctattggtt ttgctgtcgt ttttaggtct aactactctt tggttgacca
     6001 gttatcgaag acgttgtttg gctagatggc atcttcaatg gttagtggcc ttatcctatc
     6061 aagatttttt agatgtctta ctgagtctgt ttcaatttgt cattattata cttgttttat
     6121 tcttttactc agctactatt aatctaggag aggttctgac ctttttgaca caaactagct
     6181 ggcattggca gattctttgt tatttagtgt tgtatcttat ggccatcata gagatgacgc
     6241 ttttagtttt aattcttatc tttgatgttt tgctccagaa agatagtcga ttgctcttta
     6301 aaaaaataac ttggctgcct tttagacaag ataaaccagt cttaagtata cttttgctag
     6361 gcatagttat tctagtagac agtctctttt atttgggctt gcttatatta ttaggagaac
     6421 agtcgctaac aagtttagca acgcttattt taggctatgg gatagtcaag gcttgtcgct
     6481 attcaggttg gttaaatgta ctattagctt tttgtctttt cactatagtt ggactatggg
     6541 cagttacggc aactttatta tatggttggc tagtaggtgc gatgatatta acggtgactt
     6601 atttgatgat tagttgcaaa gagtattagc aatattaaaa aggagtgata tatgagtttt
     6661 gtacaattaa caaatgttgt caagtcctac aaaaacggca agaaagctgt caatgatgtt
     6721 tccttgtcta ttgaagcagg taatatttat ggtttgttag gaccaaatgg tgctggtaag
     6781 tctaccttga ttaatcttat cttaggcttg atccctttga gttctggtaa aattactgtt
     6841 ttagggcaat cccaaaagac tattcgaaaa ataagttcgc agataggtta tgttcctcaa
     6901 gacattgctg tttatccaga cctaactgct tatgaaaatg tagaactatt tgggtcactt
     6961 tatggcttaa agggagctca gcttaaaaaa caagttctaa aaagtttaga atttgtgggg
     7021 ctacactccc aagctaagca gtttccaagt caattctcag gaggaatgaa gagacggtta
     7081 aatatcgctt gtgcgctagt tcattcacct aaattaatca tttttgacga accgactgta
     7141 gggattgatc ctcaatcacg taatcatatt ttagagtcga ttcgtttgct aaacaaagaa
     7201 ggtgccacag ttatttatac gacccattat atggaagaag tagaggctct ttgtgattat
     7261 atttttatta tggatcatgg tcaagttatt gaagaaggac ctaaatttga actggaaaaa
     7321 cgttacgttg caaatctagc aaaccagatt attgtaactc taacagattc acgtcatttg
     7381 gaactggcag ataagcctga ttggtctttg atagaagatg gagaaaaact catgttgaag
     7441 attgataata gtgatatgac atcagttgtt catcagctca cacaggccaa tattactttt
     7501 agcgagatta gacataacca tttgaattta gaagaaattt tcttacactt aacaggtaag
     7561 aagttacgag attagaggtt actatggttt tatttcattt aatcaaaaaa gaaagtttac
     7621 agatttttag aaaccgaaca gccttattaa tgatggtgat ttttccaatt ttgatgatcg
     7681 ttattttaag ttttgccttt aaatcaagtt ttaatactgc gacaacagtc cctaaattga
     7741 ccattcgtta ccaattagag ggtgaaaaaa cggattacca gaaaaatttt cttgcttttt
     7801 taaaagtttt aaaccaaaaa cttcatttag aggctaaacc tagtaattct cttgaaaaag
     7861 atcgacaaag ggtcagtgaa ggagccttaa cggctgtttt agaagtgaag aagaatcaga
     7921 ccattaaggt tattactaat aatattaatc agcaaaatgc agatttaatc aatatgctag
     7981 taaaaaatta tgtagataat gctaaaactt atgactcgat agcagctctt tatcctcaac
     8041 aattaaatca tatcagaaag cgaagtgtgg actatgttaa ggtcagttca atacagacaa
     8101 gtaaaggaat gacatcagct gattattatg ctatttccat gtttaccatg attacttttt
     8161 atagtatgat gtctgcgatg aaccttgttt tgtcagatcg tcaacaacgg attacaaatc
     8221 gtattcactt aacaggagtt tctccaagtc ttttggtctt tggaaaatta ataggtgcta
     8281 tgttagcaac aactgttcaa ttgagtcttt tatacatttt tacaaggttt gttttacgag
     8341 ttaattgggg cactaatgag tggatgctta ttggtataac agcctcctta gtctatctct
     8401 ctgtagctat aggtatcggg ctaggcataa gcattaaaaa tgaggctttt ttaacggttg
     8461 catccaatac tattattcct atattcgcct ttttaggagg cagttacgtt ccattgacaa
     8521 cattacacag ctctattatt aatcaattgt cgaatatatc tcctattaaa tgggttaatg
     8581 atagtttgtt ctatcttatt tttggtggtc aatataatcc gattcctgta actttgatcg
     8641 ttaatattag tatcggaaca atttttataa tattgtcatt gataggtatg agaaagcagg
     8701 tgacgacatg atttgtttta taaaaactct atttgttaag ataaagcgca aaaaaacaag
     8761 ttatgtgaca ttctttttaa tgcctatttt aacgacactt ttggctttat ctttgagttt
     8821 ttcaaataat aatcaggcta aaattgggat attagataaa gataatagtc agatatctaa
     8881 acaatttatt gctcaactaa agcaaaacaa aaagtacgac atttttacca aaatcaaaaa
     8941 agagcatatt gatcactacc ttcaggataa atctctagaa gcggtattga ctattgacaa
     9001 agggttctca gataaagtgt tgcaaggaaa atctcaaaaa ctcaatatac gttcgattgc
     9061 taatagcgaa attacagagt gggtaaaggc acagaccaat tatctattgg aaaattataa
     9121 tattataggg gatgtggctc taggtaacga agatactttt aatagaattc tccaaaagaa
     9181 ccaacagtta aattatgatg ttaagcaagt aactttgaca gaccgatcac gtagcaaagc
     9241 agtatcttcc acaacgacag gatttttgct tattctaatg ttaggtagta cgagcgtgat
     9301 ttacagtggt attttggcag ataaatctag tcagttatac catcgattaa tgttatcgaa
     9361 cttatctcgt tttcgctata tgttgagtta cgtctgtgta ggatttgttg cttttacgat
     9421 tcaaattgtc attatgctga gtttgttaaa agtatttaat attagttttt ttgttccgac
     9481 atcacttctt ttgattattt ttttcctttt tagtttatta gcgataggct ttggcctgct
     9541 gattggagct atcacacaaa attcccaaca aagtagccag ttagctaatc ttattgtaat
     9601 gccgacttca atgttggctg gctgtttatg gccattgtct attacgcctt cttatatgca
     9661 agcaattggt aagttattac cacaaaattg ggttttatca gccatagcta tttttcaaag
     9721 tggagagacc ttatctcagg cttggccata cttgttagct ctaatgggaa cagcactagc
     9781 tttgattagt ttttcaagtt tattattaaa acctaccaaa ctataattag tcttttgtta
     9841 aaaatacttt cctaattagc taactaccag gtagcccttt tattggctta tatgcaataa
     9901 aagggttgct ttttgcttat attttctcta gtgcacttat cttttgttaa aagcgattgc
     9961 gatgttactg ttgttactgt gttttttaga gagcatatta tcaaaagcga cctctctaga
    10021 aagttcgttt ttgttgataa atgagttgtc aaagtatttt aaaaaaacgt tttcaataaa
    10081 cataaaaact aatgttatta aaaaaaggtg taaaaacgta tttattttat gaaatgtttt
    10141 tgttacaata agcatgtatc gaatgctata aagctgtctt gttcgctatc aggggtgctt
    10201 gtgatgttat gtcagatcaa acaagtcttt aattgggtga cttaacagat taaaagaaaa
    10261 gatctaatcg tgttacttga tagtataatt aatgcaaaca gaaagtgtat cccaattcat
    10321 agtttcaggt ggaggttaat attcaaaaat aaaatcttgt tgttgtctta aactaatcac
    10381 attaaaagga gatatcatga ttaacaagaa atatataata cctgtttcat tgttgacact
    10441 agctattacg cttactagtg ttgaagaagt tacttcacgc caaaatttga cttatgccaa
    10501 tgaaatcgta acacaaaggc caaagagaga atctgttatt agtgataaat cgaattttcc
    10561 cgtcatatca ccttacctag caagtgtgga ttttggtgag agaaaaacac ctttgccaac
    10621 acctgataaa ggagtaaaag taactactga acagtctatt gctcaagtaa gaaaggggcc
    10681 tgaagaaaga acctatactg ttactggcaa gattacgagt gtgatcaatg gctggggagg
    10741 ctatggcttt tatattcaag atagtgaagg tattggactt tatgtttatc ctgaaaaaga
    10801 tttaggatac agtaagggag atattgttca attaacaggt acacttactc gctttaaagg
    10861 tgatttacaa ctccaacagg tgactgcaca caaaaagtta gagttatctt ttccgacttc
    10921 tgttaaagaa gcagtaatat cagaattaga aacaacaaca ccctcaacat tagttaagtt
    10981 atctcacgtg acagttggag aattatcaac tgatcaatat aacaacacat ctttccttgt
    11041 aagggatgat agtggtaaaa gtatagttgt tcatatagat catcgtacag gggttaaagg
    11101 ggctgatgtt gttactaaaa taagtcaggg tgatttgatt aacctcacag ccatattgtc
    11161 tattgttgat ggtcagttac aattaagacc gttttctctt gaacaattgg aagtggttaa
    11221 aaaggtcaca agctcaaata gtgatgcttc atctcgtaat attgtgaaaa taggcgagat
    11281 tcaaggagct agtcatacgt cgccacttct caaaaaagcg gtcaccgtag aacaggttgt
    11341 tgtcacttat ttagacgatt ccactcattt ttatgttcaa gatcttaatg gtgatggtga
    11401 tttagcgact tcagatggta ttcgtgtttt tgctaaaaac gctaaggttc aagtcggcga
    11461 tgttttgacc atttcaggtg aagtggaaga attctttggt cgtggttatg aggaacgtaa
    11521 gcagactgac cttactatca cccaaattgt ggctaaagca gtgaccaaaa cagggacagc
    11581 tcaagttcca tcaccgcttg ttttagggaa agatcgtatc gcgccagcca atattattga
    11641 taatgatggc ttgcgtgtgt ttgatccaga agaagacgct attgattatt gggaatcaat
    11701 ggaaggcatg ttagtggcgg ttgatgatgc taaaatcctt ggtccaatga aaaataaaga
    11761 aatttatgtc ttacctggct ctagtacaag accgttaaat aattcaggtg gagtattact
    11821 tccagctaat tcttataaca cagatgtgat tcctgttctt ttcaaaaaag gcaaacaaat
    11881 tattaaagca ggagactctt acaaaggaag attagctggg ccagtatctt atagctatgg
    11941 taattacaag gtctttgttg atgacagcaa aaacatgcca agtttaatgg atggtcatct
    12001 aaaacctgaa aaaacaaact tgcaaaaaga ccttagcaag ttaagcattg cttcttacaa
    12061 tattgaaaac ttctcagcca atccttcttc aactaaagat gagaaggtca aacggattgc
    12121 cgaatccttt attcatgatc tgaatgctcc agacattatt ggattaattg aagtccaaga
    12181 taataatggg ccgactgatg atgggacaac ggatgcgaca caaagcgcac aacgcctcat
    12241 tgatgctatt aaaaaactag gtggcccaac ttatcgttat gttgatattg ctccagaaaa
    12301 taatgttgac ggaggtcaac caggtggtaa tattcgaaca ggattccttt atcaaccaga
    12361 gcgcgtcagc ctttctgata agccaaaagg cggtgctcgt gatgctctaa cttgggttaa
    12421 tggagaatta aaccttagtg ttggtcgaat tgatccaact aacgccgctt ggaaagatgt
    12481 tcgtaaatca ctagcagcag aatttatctt ccaaggtcgt aaagtcgttg ttgttgcaaa
    12541 tcatttgaac tctaagcgtg gggataatgc tctttatggt cgtgtgcaac cagtcacttt
    12601 taaatctgag caaagacgtc acgtcttggc taatatgcta gcacaatttg cgaaagaagg
    12661 ggcaaaacac caagctaata ttgtgatgct aggtgacttt aatgattttg aattcacaaa
    12721 gacgattcaa ttaatcgaag aaggtgatat ggttaacttg gtgagccgac atgatatttc
    12781 agatcggtat tcttattttc accaaggcaa taatcagacc cttgataata tattagtttc
    12841 acgccattta cttgatcact acgaatttga catggttcat gtgaattccc catttatgga
    12901 agctcacgga cgcgcatcag atcatgatcc attgttactt caattatcat tttccaaaga
    12961 aaatgataag gcagagtctt ctaaacaaag tgtaaaagct aaaaaaactt caaaaggaaa
    13021 actgttgcca aaaacaggag atagtcttgt ttatgtgata acgctactag gaacggctag
    13081 tttattagtg cctattttat tattgactaa aggcaaaaag gaatcatagc gatttgaaga
    13141 attggagttc ataaagagtc gttaagggct tgatatactt acgttagacc ttaagctaaa
    13201 atggatgact atataaaaac taatattgat aacaaaagaa gataacaata agacagcttt
    13261 acttgctaaa gacttttgtc aagctaattg ttttatggta caatgtaacc gttgctttgc
    13321 aacccttggt gcttagttcc ctttcaccaa gcatattaga aacgtagata gcttttgaga
    13381 gttatccaga cgttaaagga gaaaaaatga caaaattgac tgtacacgac tatgttcaca
    13441 ttgggctagt agctgccttg tatgttgtct taactattac cccgccttta aatgcgattt
    13501 cttatgggat gtatcaattt agaatatctg aaatgatgaa tttcttagct ttttatcatc
    13561 gcaagtatat tattgcggtg actcttggat gtatgattgc taacttttat agtttcggac
    13621 tgattgatgt ctttgtaggc ggcggttcaa ctcttatttt tgtgacctta ggtgttattt
    13681 tgtttagtaa gtatcaaaaa gattatcttt ttaatggcat ttttaataaa gcttttgttt
    13741 acttttcttt cttttttgca acttccatgt ttactgtagc aatcgaactt tacttctttg
    13801 gagctccatt tttattaaca tggtttacaa ctgcgttggg agaattagta tctctgctca
    13861 taggatcact tattattgat aagttgtctc aaagaatttc cttttagtaa tgcatcatac
    13921 tcaaaagagt tgggtcaata cccttctctt ttttatgttg tttgtaatgt taaaatcgtt
    13981 ctagatagaa atatttaaca ctttagctaa tagtaccata tggagtggcc aacgattact
    14041 tttgatgttg ttatgatata gaaatagctc atttgttatc ttttatgata aaataaaagt
    14101 atgaaaaaac gcataaaaga attaacagat cttcttaacc gttaccgtta tgactattat
    14161 actaaagatg ccccatcagt ttctgacagt gactatgata agctttatcg tgaactggtg
    14221 actttagagc agtcatatcc cgagtatgtc ttgcaagata gcccaacgca gcaggttgga
    14281 gggactattt taaaggggtt tgaaaaatat cgacatcagt atccgctttt tagtttgcag
    14341 gatgcttttt cacgtgagga gctggatgct tttgataagc gcgtcaaagc cgaatttcca
    14401 aatgccacct atctagcaga gttaaaaatt gatggtttat ctatttcctt gagttatgag
    14461 aatggcttct tacaggttgg agcaacacgg ggtgatggca atatcggtga aaatatcaca
    14521 gaaaatatca aaaaaataaa ggatattcct caccaattga gtgagccttt aaccatcacc
    14581 gttcgaggag aggcttacat gtctcgtcag tcctttaaag cgatcaatga agcacgccaa
    14641 gaaaatgggg agactgaatt tgctaatcct agaaatgctg ccgctgggac actaaggcag
    14701 ctagatacgt cagtggttgc taaacgtcaa ctagccactt ttttgtatca agaagctagt
    14761 ccgacagcta gaaatcaaca aaatgaggtc ttagcagaat tagcaggtct aggtttttca
    14821 gtaaatccgt attatcaact cacatcgtct atggatgaga tttgggattt tatcaaaact
    14881 attgaggcaa aaagagatca attagcttat gacatagatg gcgttgttat taaagttaat
    14941 agcctagcca tgcaagaaga gctagggttt acggttaaag ctccacgctg ggccattgct
    15001 tacaaatttc cagcagaaga aaaagaggca gaaatccttt cggttgactg gacagtggga
    15061 cgaacaggcg tggtcacacc tacagcgaat ctaactcctg tgcaactagc ggggacaacc
    15121 gtgagtcgtg caaccctaca taatgtggat tatattgccg aaaaagatat ccgtattggc
    15181 gatacagtga ttgtatataa ggcaggggac attattcctg ctgtcttaaa tgtcgttatg
    15241 agtaagcgga accagcaaga agtcatgctt attcctaaac tatgcccatc ttgtggtagt
    15301 gaattagttc attttgaaga tgaggttgct ttgcgttgta ttaatccgtt gtgtcctagt
    15361 ttgattcagc gaagtttgga gcattttgca agtcgtgatg ccatgaacat tactgggctg
    15421 ggaccagcta ttgtggaaaa actattttta gcggggtttg ttcatgatgt tgctgatatt
    15481 taccagttga ccaaagaaaa tttcatgcaa ttagatggca tcaaagaaaa gtcagctgat
    15541 aaattgctcg ctgcgattga ggcttctaaa tcaaattcag ctgaaaaact gttatttggt
    15601 ctaggaattc gtcatattgg ctctaaagtt agtcgcttaa ttttagaggt atacggagat
    15661 atttctgctc ttttaaccgc taaagaagag gagatcgcaa ggatagatgg ccttggctca
    15721 acgattgctc aatcacttac tcaatacttt gaacaaaaaa cggctgcgat tttagtagac
    15781 gagttaaaga cagcaggtgt caacatgcat tactcaggtc aaaaagttaa tagtgacgca
    15841 gcgctttttg gtctaactgt tgttttaact ggcaaattaa atcagctgaa ccgaaatgag
    15901 gccaaagata aattagaggc attaggtgcc aaagttactg gaagtgtatc taagaaaaca
    15961 gatttagtta ttgcaggtag tgacgctggt tctaagctag aaaaagcaaa gagcttagga
    16021 attcggattg aagatgaaga ttggctacgc cagctttaag tgaggtaatg ttatgaaaaa
    16081 acaattgaga gcacgtctca tttataatcc aacgtcagga caagaactta tgagaaaaag
    16141 tgttcctgaa gttttagaca tattagaagg gttcgggtat gaaacatctg cctttcaaac
    16201 aacagcccaa aagaactctg ctctaaatga agcaagaaga gcggcaaagg caggttttga
    16261 cttattgatt gctgctggag gtgatggcac tattaacgaa gtggtcaatg gaattgctcc
    16321 cttgaaaaag cgccctaaaa tggccattat tccaacaggt accactaatg attttgctag
    16381 agcgttaaaa gtaccaagag gaaatccgag ccaagcagca aaacttatcg gaaaaaatca
    16441 gactatccag atggatattg gtagagctaa gaaagatact tatttcatca atattgctgc
    16501 agcaggaagt ttgacggaat taacttacag tgtaccaagt cagttaaaaa cgatgtttgg
    16561 atacttggct tatcttgcta aaggagtaga actgctccca agagttagca atgtgcctgt
    16621 taaaattacg catgacaaag gcgtctttga aggtcaagtt tctatgattt ttgcagctat
    16681 taccaattct gttgggggat ttgaaatgat tgctcctgat gcaaaactag atgacggtat
    16741 gtttacgctc attttaataa agacagcaaa tctttttgaa attgtacatc ttttgcgttt
    16801 gattttggat ggtggtaagc atattacaga tcgccgtgtc gaatacatta agaccagtaa
    16861 aatagtcatt gaaccccaat gtggtaagcg aatgatgatt aatttagatg gcgagtacgg
    16921 aggagatgct ccaattacat tagagaacct aaaaaatcat atcacttttt ttgcagatac
    16981 tgatttgatt tctgatgaag ctttagtctt agatcaggac gaattggaaa ttgaggaaat
    17041 cgtaaagaaa tttgctcatg aagtagaaga cttagaacaa gaattagaag aataatacaa
    17101 tagttattag ctactgacag tttagtcaaa tgcactacta ttagaatcta agatttttaa
    17161 atcaattgag gtagtgtttt ttgatgcgct caaagagtca atttattcat atgaggggcc
    17221 catttgaggt ctctcttttt tgatcatatg caagaaaatg ccatgtttta ggggtgttat
    17281 tatacccttt ttggaatctt gttgcctttt tgttataata agagtgtaat tctattttta
    17341 aaaagatctt aacaaagaca gactcgttta tcaaaaaggt tagtattagt ctaagaaagc
    17401 gtactcagtc taaagaaatc tgttgacatt cttaatttta aggaatagaa tagcaaagta
    17461 aaaaaaattt aaaggagtat tctactatga atcctatttt cgcattggct ttggcctgtt
    17521 ttggtgtttc tcttgccgaa ggtttcttga tggcaaatct ttttaaagca gcatctcgcc
    17581 aaccagaaat cattggtcaa ttacgttcat taatgatctt gggtgttgcc tttatcgaag
    17641 gtactttctt tgttaccctt gttatggcct tcattcttaa ataacagcct atttgataat
    17701 agaaaaggag ggtgttagat ggaagaagct aaaataccca tgctaaagct tggtccaata
    17761 acctttaatt tgaccctact tgctgtttgt attgtcacaa ttgctgttat ctttgccttt
    17821 gttttttggg caagtcgcca aatgaaattg aaaccagaag ggaagcaaac tgctttagaa
    17881 tatttaatca gttttgtgga tggtattgga gaagagcact tagatcataa tctacaaaaa
    17941 tcttattcgc tgttactctt taccattttt ctctttgtgg ctgtcgctaa taatttaggg
    18001 ttatttacta agttagagac agttaatggc tataacctat ggacatcgcc aacagccaat
    18061 ctggcttttg accttgctct atctcttttt attaccttaa tggtacacat tgaaggggtt
    18121 agacgtcgtg gcttggttgc ccatttgaaa cgtttggcta caccgtggcc aatgactccg
    18181 atgaatttat tagaagagtt cacaaatttc ttatcacttg ccattaggtt attcggtaat
    18241 atctttgccg gggaagttgt tacaggtttg attgttcaac tggccaatta tcgagtttat
    18301 tggtggccga tcgctttcct agtcaatatg gcgtggacag ccttttcagt ctttatttcc
    18361 tgcatacagg cttttgtttt cacaaaacta acagcgacct atctaggaaa gaaagttaat
    18421 gaatcagaag aataaggaag gagaacaaac gaatgtcaat cacatttggt gaactcgttg
    18481 ggaattttat tctagtaaca ggttctgtaa tcgtcttgtt actcttgatc aaaaaattcg
    18541 cttggggtgc aattgaatcg attttacaga cacgctcaca acaaatctct cgagatattg
    18601 atcaggctga gcaatcacgt ctaagtgctc aacagttaga ggcaaaaagt caagctaacc
    18661 tagatgctag tcgttcacaa gcaagtaaaa tcattagtga tgccaaagaa attggtcaat
    18721 tacaaggtga taaattggtg gcagaagcta ctgatgaagc aaaacgcttg aaagaaaaag
    18781 cgttgacaga tattgaacaa agcaaatcag acgctatttc agcagtcaaa acagaaatgt
    18841 ctgatttaac ggttctttta gcggaaaaaa ttatgggagc caatcttgat aagacggcgc
    18901 aaagccagct tattgacagt tatcttgatg acttaggaga agcttaatga ccaaaaaaga
    18961 acaggctctt atcgagcaat atgcaaaaag ccttgttgag gtggcaagtg aacatcattc
    19021 tcttgatgcc ttacaagctg atgtgcttgc gattttagag acgtttgtaa caactaatct
    19081 tgatcaaagt ctatcaagtc tagctgttcc gcatgctgaa aaaataaaat tgctaacctt
    19141 attaaaggga aataattctg tttatatgaa taatttcttg aatctcattt tacaaaacga
    19201 acgtgaagct tatttgtatc aaatgcttca ggctgtttta aatgaaattg caatagtttc
    19261 aaatcagtat gatgtgacag ttacctcatc actacctttg actgaggagc aaaaaagccg
    19321 tgttcgagca gttgttgcaa agaaatttgc tgtaacagcg ggtcgtttaa ttgaaaaagt
    19381 agatccttcg cttattggag gatttattat cagcgtcaat aataaagtaa ttgataccag
    19441 tattcgtcgt caattgcaag catttaaaat gaatttaaaa tagaaagtgg tgtgactttt
    19501 ggcaattaat gcacaagaaa ttagcgcttt aattaaaaag caaattgaga acttccagcc
    19561 aaatttcgat gtcacagaaa ctgggatcgt tacctatatt ggtgacggta ttgcacgtgc
    19621 ccgtggatta gataatgcca tgagtggtga acttcttgaa tttgaaaatg gtgcctacgg
    19681 gatggctcaa aaccttgagt caaatgatgt gggtattatt attcttggtg atttttcagc
    19741 aatccgtgaa ggagatgtgg ttaagcgcac cggtaaaatc atggaagtac cagttggtga
    19801 agctctcatt ggacgtgtgg taaacccact tggacaacca gttgatggct tgggagatat
    19861 tgaaacaact ggctttagac cagtagaaac gccagctcct ggtgttatgc agcgtaaatc
    19921 cgtttctgaa cccttacaaa ctggattaaa agcaattgat gctttggttc caattggtcg
    19981 tgggcaacgt gagttgatta tcggagaccg tcaaacagga aaaacatccg tagctattga
    20041 tgcgattttg aaccaaaaag gtcaagacat gatttgtatc tatgtggcta ttggtcaaaa
    20101 agaatcaacc gttcgtacac aagttgaaac ccttcgccgt tacggtgcct tggattatac
    20161 tattgttgtg acagcgtcag cctcacaacc atcaccattg ctctttatcg ctccttatgc
    20221 gggtgttgcc atggctgaag aatttatgta ccaaggcaag catgtcttga ttgtctatga
    20281 tgacttatca aaacaagcgg tggcttatcg tgaattgtct ctcttgcttc gtcgtccacc
    20341 aggtcgtgag gcttacccag gggatgtttt ctacttgcat agccgtcttt tggaacgctc
    20401 tgcaaaagtt tctgatgatt taggtggagg ttctatcaca gctctaccat ttatcgaaac
    20461 acaggccgga gatatctctg catatattgc gactaacgtt atttcgatta cagacggaca
    20521 aatcttcttg caagagaacc tctttaattc aggaattcgt ccagcgattg atgcaggatc
    20581 atctgtctca cgtgtaggtg gttcagctca aattaaagcg atgaaaaagg ttgctggtac
    20641 tcttcgtttg gatttggctt cctatcgtga attagaagcc tttacccaat ttggttcgga
    20701 ccttgatgct gcaacacaag caaaacttaa tcgtggtcgc cgtacggttg aaatcttgaa
    20761 gcaaccattg cataaaccgt tacctgttga aaagcaagtc gttattcttt atgcccttac
    20821 tcatggtttc ttagatgatg ttcctgtaga tgatattttg gcttttgaag aagctcttta
    20881 cgactacttt gacgttcatt acaatgattt atttgaaact atccgtacca caaaagacct
    20941 tcctgaagaa gctgcccttg atgccgctat taaagcgttt aaagaacact caaactttaa
    21001 gtcatagagg gaggatacta gtatggcagg ctctctaagt gaaattaaag ctaaaattat
    21061 ttcaactgag aaaacaagta aaatcactag tgccatgtgt atggtttctt ctgcaaaact
    21121 tgttaaatct gagcaagcag ctcgtgattt tcaaatttac gcctcaaaaa ttcgccagat
    21181 tactacagat ttattgaaat cagaattaac cataggatct gataatccga tgttggtgtc
    21241 tcgtcctgtc aaaaaaacag gctatattgt catcacgtct gataaaggac ttgttggagg
    21301 ttacaattca aaaatcttga aatctgttat ggatatgatt acagagtacc atgctgatgg
    21361 tgactatgaa atcatttcta ttggtagtgt tggttcagac ttcttcaaag caagagggat
    21421 gaatgtggct tttgaacttc gtggacttgc ggatcaacca agttttgaac aagtgagaca
    21481 aatcatttca caatccgttg acatgtttgt caatgagatt tttgatgagt tatatgtctg
    21541 ttacaatcac catgtgaata gcttaaccag ccaagtccgt gttcaacaga tgttgccaat
    21601 ttctgacttg gttgctgatg aagcagcaga agaaggtgtt actgggtttg aattggaacc
    21661 taatcgtcat gatattttag atcaattgtt acctcaattc acagaaagtt taatttatgg
    21721 ggctatcatt gatgctaaaa cggctgaaca tgcagcaggt atgactgcca tgcagacagc
    21781 gacagataac gctaagaatg tcattaacga tttgaccatc caatataacc gagctcgtca
    21841 agcagcaatt acacaagaaa ttactgaaat tgttgcagga gcaaatgcac tagaataaaa
    21901 aataacgctg actagcgatt aggttattgt cagcattcaa ttttatcaat cgagataaaa
    21961 tgacttatgg gacttttcta ttgaaagact gctcttttca gtataaaaga agttagcaag
    22021 actaactaag ccctgactat cgaatataag gagaaatgaa tgagctcagg caaaattgct
    22081 caggttgttg gtccagtagt agacgttatg tttgcgagtg gggacaaact tccagagatt
    22141 aataatgcat tgattgttta taaagatagt gataaaaagc aaaaaatcgt ccttgaagtt
    22201 gctctggaac ttggtgacgg tatggtgcga acaatcgcta tggaatcaac tgatgggctt
    22261 acacgtgggt tagaagttct tgacactggt cgtgcgatta gcgtaccagt aggtaaagaa
    22321 actttgggac gcgtctttaa tgtacttgga gaaaccattg atttggaaga accatttgca
    22381 gaagatgttg accgtcagcc gatccataaa aaagcaccat cgtttgatga attatcaaca
    22441 tcatcagaaa ttcttgaaac tggtatcaag gtaattgacc ttcttgcccc ttaccttaaa
    22501 ggtggtaaag ttggactttt cggtggtgcc ggagttggta agactgtcct tatccaagaa
    22561 ttaatccaca atatcgccca agaacacgga ggtatttcag tatttaccgg tgttggtgag
    22621 cgaacacgtg aaggaaatga cctttactgg gaaatgaaag aatcaggcgt tattgaaaaa
    22681 accgccatgg tttttggtca gatgaatgag ccgcctgggg cacgtatgcg tgtagccctt
    22741 actggtttaa ccattgctga gtatttccgt gatgtagaag gccaagatgt tttgctcttt
    22801 attgataata tcttccgttt cactcaggca ggttcagaag tatcagccct cttaggccgt
    22861 atgccttctg ctgttggtta ccaaccaaca cttgctactg aaatggggca attgcaagaa
    22921 cggattacat caactcaaaa aggttctgtt acatctatcc aagcgattta tgtaccagca
    22981 gatgattata ctgaccctgc gccagcaaca gcatttgctc acctggattc aacaactaac
    23041 cttgaacgta aattgacaca aatggggatt tatccagccg ttgatccatt ggcttcaagt
    23101 tcacgggctt tatcacctga gattgttggt gaagagcact atgctgtggc aacagaagtt
    23161 caacgtgtgc ttcaacgcta ccgtgaatta caagacatca tcgctatttt ggggatggat
    23221 gaattatcag atgaagaaaa aacattggtt ggacgtgcgc gtcgtatcca gttcttcctc
    23281 tcacaaaatt ttaacgttgc tgaacaattt accggtcttc ctggttctta cgtgccagtt
    23341 gctgagacag ttcgcggctt taaagaaatt cttgaaggaa aatacgatga tcttccagaa
    23401 gacgcctttc gttcagttgg tccaatcgag gatgtgatta aaaaagccga aaaaatgggc
    23461 ttttagtgag gtgatgccat gacacaaatg actgttcaag tggtaacgcc agatggaatc
    23521 aaatatgatc accatgctaa atgtatttcg gtaacaacac cagatgggga aatggggatt
    23581 ttacctaatc acatcaattt aattgcacct ttgcaagtcc atgaaatgaa aattcgccga
    23641 ggtggtgaag atgaaaaagt ggactggatt gctatcaatg gtggtattat tgaaatcaaa
    23701 gataatgtgg ttaccgttgt cgctgattct gcagaacgtg accgtgatat cgatgtcagc
    23761 cgagcagagc gagcaaaact aagagcagaa cgtgaaattg cacaggctga aacgacccac
    23821 aacattgatg aagttcgtcg tgccaaggtt gccttgcgcc gcgctttgaa tcgtatcaac
    23881 gttagtaaaa agtaagtggt gttgataaaa gacaaggata agtaagaaag gtttttaacc
    23941 tattattttg tttgctgagt ctttttaaca tcagtttctg agagtttgac catactacct
    24001 tctctaaaca cgttattatt gttgagagga gttatatggg ggaactcttt tttgtatcca
    24061 cgttgttagt agaaactcag taatgacgct taatgtattt ttaggctatc aacttagtca
    24121 gagaggatgt caatttaatt gataagttgg acggatcaag atggtatgtt ataataatcc
    24181 tatggaatta ttaatgaaga tcattgcctt ttcgtgtcat ttatttttta ttggccttag
    24241 ttaccaatta ttgattagtg tgattgactg gacaaaattt agtcattatc atccagaaaa
    24301 tcttggccgg ctacgacttt ttgtcttttt attagctact gccctagggt atttggtgag
    24361 ccattgtatg ctggaattgc ttcaaattag ccagacgctc ttttttgagt tctgctaata
    24421 ctggaataaa agaagtatgg tataatttta ctacgactaa gagatagata agggagaaaa
    24481 ttgtggataa aataatcatt gaaggtggtc aaacacgctt agaaggagaa gttgttattg
    24541 agggtgctaa aaacgcagtt cttcctttac tggcagcatc tattttacct tcaaaaggaa
    24601 aaacaattct tagaaacgtt cctattctat ctgatgtttt taccatgaat aacgtggtac
    24661 gtggtttaga tattcgtgtt gattttaatg aagcagctaa cgaaatcaca gttgatgcct
    24721 caggacacat tttagatgaa gccccttacg agtacgtgag ccaaatgcgt gcctctattg
    24781 ttgttttagg accaattttg gcacgtaatg gccacgcaaa agtatcaatg cctggaggct
    24841 gtacgattgg cagtaggcct attaatttgc acttaaaagg attagaggct atgggggcaa
    24901 cgattactca aaaaggtgga gatattaccg ctcaagcaga tcgactgcaa ggtgccatga
    24961 tttatatgga cttcccatct gtaggagcta cccaaaactt gatgatggct gccactttag
    25021 ctgatggtgt gaccactatt gaaaatgctg ctcgtgagcc tgaaattgtt gatttagctc
    25081 aatttttgaa taaaatggga gctagaattc gtggtgctgg aacggagacg ttaacgataa
    25141 caggcgtcac aagtcttcat ggggtggagc acgatgtggt tcaagaccgt attgaagcag
    25201 gtacttttat ggttgcagcg gcgatgactt caggcaatgt tttgattaga gatgctgttt
    25261 gggaacataa tcgtccattg atttcaaaat taatggaaat gggtgtttct gtaacagaag
    25321 aagaatatgg tattcgcgtt caagcaaaca cgccaaagct caaacctgta acggttaaaa
    25381 ccttgcctca tccaggtttt ccaacagaca tgcaagctca atttacagct ttaatggcag
    25441 tggtcaatgg agagtctact atggttgaaa ctgtctttga aaatcgattt caacatctgg
    25501 aagaaatgcg acgcatgggc ttacaatctg aaatccttag agaaactgcc atgattcatg
    25561 gtggaagaca actgcaaggt gctcctgtga tgtcaacaga tttacgtgcc agtgctgccc
    25621 ttatcttgac agggattgtt gctcaaggag ttacaatagt taataatttg gttcatttag
    25681 atcgtggcta ctatcaattt catgaaaaat tagcaaagct tggagctact attagtcgta
    25741 gcagtgaggt ctagcttatg acaaatggtt taaaatatgt cttagaacaa atgttattac
    25801 ttttagtaat tgctgccttg gcgtgtcttt ttttagccat tggacttatg attggttata
    25861 gttttatggg agatggccat agtccatggc atattttatc tatggataag tgggcagagt
    25921 tagtgaataa atttactgga aagtaggcct tgcctacttt ttatagcatc tgagaggaag
    25981 tatgttaaca aggaaaaaac gaaaaagggt gcaagagcaa aaggttccta aaagagctaa
    26041 tgccttactt actaagtcaa cccggcaata tcaagaccgt tcacaactta agaaaggtta
    26101 ccgttcattt aagccagcag gttggcaccg attgcaccac ttaaaaggaa gttatgatca
    26161 cgcggttgat agagggcatt tgctaggtta tgctttagtt ggtggactga aaggttttga
    26221 tgcttctact ggtaatcctg ataatattgc cactcaacta agttgggcta atcaagcaaa
    26281 taaaccctac tcgacaggtc agaattacta tgaaggttta gtacgtcgtg ctttggataa
    26341 ggggcatcgc gtccgctacc gtgtcaccct actttatgat ggtgataatc tactagccag
    26401 cggtagccat ttgaaggcta aatcctctga tgacagcttg gcttttaacg tgtttgttcc
    26461 aaatgtccaa gcaggattga ccgttgacta tcggacggga caaatagcta tcaatctcta
    26521 agcgaaaagt cactgattta agattgtcac taagcacttt ttttgataga atagaactaa
    26581 ttgaataagt gtctatgaga ctagtactaa tagagaaatt aacagggagt gagggccgtg
    26641 actggaagcc ttcttaaggg aactattagg aattcactca gctaaagaca attaattaag
    26701 gtctgataac atcagataaa aacggatggt accgcgtgtc aacgctccgc ttatcaagtg
    26761 gaggagtggc atgctttttt catcgccaaa agaagggaaa actatggatt tacaagcaca
    26821 attagaggaa ttaaagtcaa aaacattgga gaccttacag tctttgacgg gtaatcatac
    26881 caaagaactg caagatttac gcgtggctgt tcttgggaaa aagggatctt tgacagaatt
    26941 actaaagggg ctaaaagact tgtctaatga cttgcgtcct gtggttggta aacaggtgaa
    27001 cgaagttcgt gacttattga caaaagcctt tgaagaacag gccaaaattg tagaagctgc
    27061 taaaattcag gcccaacttg atgctgaaag cattgatgtg actttaccgg gtcgtcaaat
    27121 gactctgggg catcgtcatg tgttgacaca aaccagtgaa gaaatcgaag atattttctt
    27181 aggaatgggt tttcagattg ttgatggctt tgaggtggaa aaagattatt acaactttga
    27241 gcgcatgaat ttgccaaagg atcaccctgc ccgtgacatg caagatacat tttatatcac
    27301 agaagaaata ttgttacgaa ctcataccag tcctgtgcag gcccgtactc ttgatcaaca
    27361 tgatttttca aaagggcctt taaaaatggt ttctccaggt cgtgttttcc gtcgtgatac
    27421 tgatgacgct acccactcac atcaattcca tcaaattgaa ggtttggttg tgggcaaaaa
    27481 tatttccatg ggagacctca aagggactct tgaaatgatc atcaagaaga tgttcggtga
    27541 agaacgtagc attcgtttgc gcccgtcata tttcccgttc acagaaccat ctgttgaagt
    27601 ggatgtttct tgctttaaat gtggtgggaa aggctgtaat gtctgcaaga aaacaggatg
    27661 gattgaaatt cttggtgctg gtatggttca cccaagtgtc ttggaaatgt caggtgttga
    27721 tgcaaaagag tattcaggct ttgcctttgg tttaggtcaa gagcgaattg ccatgttgcg
    27781 ttatggcatt aatgacattc gtggtttcta tcaaggcgac caacgtttct ctgaacaatt
    27841 taactaaaac gagtcgtttg aagacctctg tcagctattt tatctaagat tgagtgaaag
    27901 ttgataggta atgataatag gttaattgtc taaggagaaa gtccctctcg cttcaacgtc
    27961 ataagggttt tgacttggaa cttaaaatac gaaaggaaat gactcaaatc acggcttgag
    28021 agctttctct agccgagtga tttgggcact aaaattatgt tagtatctta taaatggtta
    28081 aaagaattag tagatatcga tgtgacacca gtagcacttg ctgagaaaat gtcgacaacg
    28141 ggtatcgagg tagaaggaat tgaagtccct gcagaaggtt tatcaaaact ggttgtgggg
    28201 catgtgcttt cttgtgaaga tgtgccagag acacatttgc atttgtgtca ggtagataca
    28261 ggtgatgaaa cgccacgtca aattgtgtgt ggtgcaccaa atgtgaaagc agggattaag
    28321 gttatcgtgg ctgtgccagg tgctcgtatt gcggataact ataaaatcaa aaaaggcaaa
    28381 atccgcggca tggaatctct tggcatgatt tgttccttgc aagaacttgg tttgtcagat
    28441 agtatcattc caaaagaatt ttcagatggt attcaaatct tgccagagga ggctgtgcca
    28501 ggtgatgcta tttttaaata cctggacttg gacgatcata tcattgaatt gtccattaca
    28561 cctaaccgtg ctgatgcgct ttctatgcga ggtgtggcac atgaagtcgc agctatttat
    28621 ggcaagtcag tatcattccc ccaaaaaaat ctacaagaat ctgataaggc aacttcagaa
    28681 gccattgaat tgtccattgc ctctgataac gttctaactt acgctagccg tgtcgttgaa
    28741 aatgtcaaag ttaagccaag tccacaatgg ttgcaaaacc ttttaatgaa tgctggtatt
    28801 cgtcctatta ataatgtggt tgatgtgacc aactatgtac tcttgtattt tggtcaacct
    28861 atgcatgctt ttgattatga taaatttgaa gaccataaga ttgtggcgcg tgcggctcgt
    28921 caaggagaaa gtttggtcac acttgatggt gaaaaacggg atttgaccac tgaggatctt
    28981 gttattaccg tggctgacaa accagttgct ttagcaggtg ttatgggtgg tcaagccact
    29041 gaaattgatg gcaactctca gacggttgtt cttgaagctg ctgtttttga tggcaaatcg
    29101 attcgtaaaa ccagtggtcg tttaaacctt cgttcggaat cctcttcacg ttttgaaaaa
    29161 ggggttaact atgcaactgt tttagaagcg cttgactttg cagcggctat gttacaagaa
    29221 ttagcagaag gtcaagtctt atcaggccat gttcaagctg gacaattgcc aacagaacct
    29281 gttgaagtct caactagcct tgactatgtg aatgttcgtt taggaacaga attaactttt
    29341 gctgatattc aaaggatttt tgaccaactt ggatttggtc taacaggaga tgaaacaagc
    29401 ttcacggtag ctgttcctcg gcgtcgttgg gatgttagca tcccagctga cttggtggaa
    29461 gaaattgcgc gtatctatgg ttatgataag ttgccgacaa ccttaccaga ggcaggggga
    29521 acggctgcag aattaacgcc aacacaggct cttcgtcgta aagtccgtgg cttagcggaa
    29581 ggattgggct tgactgaaat catttcgtat gccttgacaa caccagagaa agctgttgag
    29641 tttgcagtgg caccaagtca cctaacagaa ctcatgtggc caatgtctgt ggaacgttca
    29701 gcgcttcgtc aaaatatggt ttcagggatg ttagatacgg tagcttataa tgtggctcgt
    29761 aaacaaagta acttggctct ttatgaaatt ggaaaaatct ttgaacaaga agctaatcca
    29821 aaagaagacc ttcctaatga agtgaaccat tttgcttttg ctatttgtgg cttagtggca
    29881 caaaaagatt tccaaaccca agctcaggca gtggattttt accatgctaa aggtatcttg
    29941 gatactttat ttgcaaacct taacctcaag gttcaatatg tgccaaccaa agacctagca
    30001 aacatgcacc caggacggac agcgcttatc ctattagatg agcaagtgat tggatttgtt
    30061 ggtcaagttc atccaggaac agcaaaggct tatagtattc cagaaaccta tgtggcagaa
    30121 ttggatatgg ctgctttaga agcagcgttg ccaagtgatc aaacttttgc ggaaatcaca
    30181 aaattccctg ctatgacacg tgatgttgcc ttgttacttg accgtgaggt gagtcatcag
    30241 gccattgtaa cagctattga atcagcaggt gtaaaacgct tgactagcat taaactcttt
    30301 gacgtctatg aaggagcaac cattcaggct ggcaaaaaat caatggctta tagccttact
    30361 ttccaaaatc caaatgacaa tttaacggat gaagaagttg ccaaatacat ggagaaaatc
    30421 accaaagcat tgacagaaca agtcggtgct gaagtacgct aagaaaaaaa ctgggcctct
    30481 aaggctccgt ttttttctgt tataatagag gaaaaaagaa ctccagttca aatgattgga
    30541 gaaaaacatc agaaggtgga ggaaaatcag aatgtatcaa acaaaaataa caggcaaccg
    30601 cctttaccac acggtttcga aaggctacgg agatagtgta accttatttg gaaaaactga
    30661 tcaaggggaa acccctatga gtttactggt tattgccttg tcttcttgtg tgactatgtg
    30721 tgtgcagggt ttttaccatc gtcaatttca gcaagacaca gttgctgttt ctgttgaggc
    30781 tagttatgag gaagaagttt ttgaactact tgttaggatt gatgatgttt tagatgacaa
    30841 aaagaaagct gatttattgg cttacattgg aacttattgt cgtgtgaaac aactcctcaa
    30901 acctgaagtt acggtgacca ttacgttgga aggattgtct catgtctgat gctagtttga
    30961 aaacttacca aaaacaatgg gcttatcaaa agtattgggt catggcacac tcacagcagc
    31021 attacaatgc tttaagagaa ttgtttaaag gaaatcagtg gtcagaagaa aaggtgttga
    31081 cttttcattg tttgattgaa gaagcgcaag ccattcctcc cacagtaaaa agcttacgaa
    31141 cagcatatca gcatgtttgg gggtatttta aaaaggtagc gagtcaggaa gaaaaaaaac
    31201 atttcaaaga tttggatgct cagttggaaa ctaaatctga ggagatgcta tgctttttac
    31261 aagagatgac tgctcattat cagccctctt atctgctatc ttgccgtttg attaccaaag
    31321 gtccttaaat gctaaacaga aaagtaggga tttctgggaa gttatgctaa gctagtgata
    31381 taaataaggg ggaatgagag atgtttttag cgcttaatga aatgaaacaa tccaaattgc
    31441 ggtatggttt gattgctggt ttgctatgtt tggttgccta tttgatgttc tttttgtcag
    31501 gattggcctt tggtttgatg caggagaacc gctcggcggt tgatctttgg aaagctgaca
    31561 gtgttttact agccaaggat gctgacgcta ccttgacctt atcacaggtg tccagagctc
    31621 aagaaaatca aataacagca gacaaggtag ctcctcttgc tcaactcaat accgtggcgt
    31681 ggtcagttaa aaatcctaag gatgccgaca aagttaaggt tagccttttc gggattgatt
    31741 ctaatagctt tattcgtcct aacattgtaa aaggtcgatt atttaagact aacaaagagg
    31801 ttgttttgga tcaaagcctt gcaaaagagg aagcttttgc gattggcaag gacttttaca
    31861 catcgagttc tagtcaagca ttaactatcg ttggttatac tcaaaatgct agatttagtg
    31921 ttgcaccagt ggtttatatg aatttggaag cttttgaaac attaaaatat ggagaaccac
    31981 taccaaaaga taagcaagtt gttaatgctt ttatcactaa aggaagttta acagattatc
    32041 ctaaaaaaga cttccaaaaa ttagatatta aaacctttat tactaaatta cctggttata
    32101 gcgctcaact tttaactttt ggctttatga ttagttttct tgtcattatt tcagctatta
    32161 ttattggtat ttttatgtat attttgacta ttcaaaaggc acctattttt gggattatga
    32221 aagcgcaagg tatcgggaat ataacgattg cacaagcagt tctgctgcaa accttcttgt
    32281 taagtgcttt aggaagcggt ttagggttat tgggaacttg gttgacgtct ttagtgctcc
    32341 ctgaagcagt tcccttccaa agtaattggc tagtttactt agcgatatta gtcagtatgg
    32401 tttgttttgc tttgttagga accttatttt ctgtttttag cattgtacga attgatcctt
    32461 tgaaagcaat tggataggag gtagtgatgt cggttttaac atttaaacaa gtgaccaaaa
    32521 catttcaaga tggtcatcac gaaatcaacg cattaaaggt aactgacttt tccattgaag
    32581 ctggagaatt tgtggctatt attggaccat caggttctgg aaaatcaacc tttttgacca
    32641 ttgctggtgg cttacagacc ccaagctctg gtcagctaat cattgatggc actgattata
    32701 cgcatttatc agaaaaagag cgctcacgct tgcgcttcaa atccgttggt tttatcttac
    32761 aagcttccaa tctgatacct tttttaacgg tccagcagca gttggaattg gtcgatcatt
    32821 tgacaggaag caaagaaaaa gccaaagcca atcagttatt tgatgattta ggcattgcag
    32881 ggctaaaaca tcagttacct caagaattat ccggcggaga aaggcaaaga gcggctattg
    32941 cccgtgctct ttaccatgat ccagcactaa tattggcaga tgaacctact gcaagtttgg
    33001 atactgaaaa agcctatgaa gtggtcaaac tgttggctaa ggaaagtaaa gaaaaaaaca
    33061 aggccattat tatggtcact catgatgatc ggatgctaaa atattgtgac aaagtctatc
    33121 ggatgcaaga tggagagtta cgtcaagaga gatagtagac tggtaagagt ttatgatatt
    33181 agaagaaaaa accaaacaag cacagcactt gtctggtttt tttctaagtg tgactattat
    33241 caatacgtca ccatttccct aaagcttact atacgggatg ctaaaggtat caccatgctc
    33301 aaagtcgcca tattgataac ctcggtcaaa ccaacgttgg cgttgcttag aagttccgtg
    33361 ggtaaaacta tcaggaacgg ctctgccata ggtttcttct tgcagagtat tatccccaac
    33421 tgcgtgagct gctgccattg cttcctcaat atctcctttt tccaaaaggc cttgcccttg
    33481 aacataatta gcccaggcac cagcatagta atcagcttgt aattccaact tgacgttgag
    33541 ctgattggct ttagcctttg attttccttg tctagcgcta gcgtaattat ccataattcc
    33601 caattcattt tggatgtggt ggccaacttc atgagcaatc acataggcca tagcaaaatc
    33661 accttttgcg ccgtacttgg ttgatagttc attataaaaa gaaatatcta aatacacttt
    33721 ttgatcgcct gggcaataga aaggaccaga agaggcttgc cccctgccac aagcggtttg
    33781 agttgctcca gtatatagaa ctaatgttgg tttatgataa gttaaccctt tctcacgaaa
    33841 tgtcttagtc caatagtcct cggtagaggc gaagacctta ctgacaaaag aaacctgttc
    33901 ttgactagcc ttgtcaccat ttgtacgcgt tacttggctt gattgatagg cattgttgtt
    33961 ggtagaagaa ggcttacctc ctaaaacacc agataggcca cctcctccca taactaggag
    34021 aaggagaaga ataaccagct tggttttcca acctcctcgt gaaaagagta attgaagcag
    34081 gagaccgccc cctaggccgc cgcccccaaa agaaccagac gattgaccac gtctatcttc
    34141 aacctgttga ctttctctca aatcatccgt tttcataagt ttctcccatc tatttcttga
    34201 ttttattata aaataattct attagaattg ctatttttat gatgagatta taactaaaaa
    34261 taggaaaagc aataggtatt tgctataata taacaagggt agattcagtt tgtataaagg
    34321 agtcatatga aattaattta cacagagatg agttactcga tgacagagat tttggtgaat
    34381 gaagcacgaa aagctgctga ccaaggttat cgagtgttct atattgctcc aaattctctt
    34441 tcatttgaaa aggaaagaga agtcttaacc ttattgcctg aacgagggac tttttcgata
    34501 atagtcaccc ggttcgttca aatgtcaagg tattttacag ttgagagctc tccttctaag
    34561 caacatctag atgacacgac tttggctatg attttttatc gggccttgat gcaattaaaa
    34621 ccagaagatt tgccgagtta tggtcgtttg caaaataatt cggtttttat tgaacaacta
    34681 gttgagttat ataaggaatt aaaaaacgca caattaagcg tacatgattt aacagggtta
    34741 gactatcctc aaaaacaaga agatcttatt aaaattattg agcttgcaga gacgatcatg
    34801 attcagcaag attacaatca agatagtcct ctacaatctt ttgcaagagc aattaagtta
    34861 ggacttttaa ataatcaact atcaaaaaca gttattgtta ttgatggttt ttcacgtttt
    34921 tcagctgaag aggattattt attatcactt ttaaataaca actgtcaaga ggtcatcatt
    34981 ggcagttatg tgagtcaaaa agcttatcaa aaatctttta ttaagggaaa tatctatgag
    35041 gctagccttc attttttgca agatttggct caaaaatacc atatcaagcc ggtatttgcg
    35101 acctctaatc aagtgtttaa accagccttt tcacggctaa cacaattatt tgaagcaact
    35161 catgattttt cacaagtaga ctggcaactc caaaagaatg atcttgatca ctttagcctt
    35221 tggcaatgtc atcatcaaaa agaggaaatt gaacatgtag caaaatccat tcggcaaaag
    35281 ctatatgaag gttaccgtta taaggatatc ttagtgttgc taggagatat ggatgcttat
    35341 caattacaaa ttgggcctat ctttgataag tttgaaatcc cctactattt aggaaaagca
    35401 gagcctatgg ctgcccatcc attagtccaa tttatagaat cgctcgaacg aagtcagcgc
    35461 tataattggc gtcgtgaaga cattttaaac atgttaaaat caggactttt tggttgtttt
    35521 gatgatagtg atattgatcg ctttgaggaa tatactcagt ttgcagatat taaaggattt
    35581 actaaatttt caaagccttt taccattaac tcttctaggc agtatcctct tgacttttta
    35641 aatgaaatga gacaagacat cgttttacct ttgcaagaat tgtttaagag tcaaaaacag
    35701 cttggtgctt cacttattga caaattaata ctttttttag aaaagattag attagctgag
    35761 aatatgcaag gtttagcaca gtcccaatta gaggtggaaa aaaacgaaga agtttggaaa
    35821 aggtttacag atattttgac ttcttttcat catatctttg gccaagaaaa attacggcta
    35881 tcagattgcc ttgctttaat caaaacggga atgaaatcag ctcagtatcg tgttgttcca
    35941 gcgacattag atgttgtcac tattaaatct tatgaccttg ttcaaccaca ttcaaaacct
    36001 ttcgtttatg caattggtct aactcaatca cattttccta agcaaattca ccattcagga
    36061 ctactttctg atcaagagcg tgctagaatt aatgaaataa gaaattatcg tcattttgat
    36121 attgctagtg ccgaaaatag taaaaaaaac catcaaactg cgttatctct gtttaatgct
    36181 gctactaaag agttagttct tagtgttcca acggtaatca acgagacatt cgatgatcta
    36241 tctccttatc ttaaagaatt aataagcttt gggctacctc ttttggataa aggcaaaaac
    36301 tatctatctt atgataatag cgatattggt aactataaag ctctcttgtc acaaattatt
    36361 gctattaacc gacaagatct tatagaaatg tcagatcaag ataagatgtt ttggactgtt
    36421 gtcttacgtt atctcaggaa acagttaaga aagcaacagc tagagctacc tacttcagat
    36481 tatcgtttat caacaaagcc tttgtctaaa gaagttatcg aggtatgttt tccaaaggga
    36541 atccctttaa agctatctgc aactgcttta accgtttttt ataataatca gtacaactat
    36601 tttttgaaat atgttttgaa tttaaacaaa acagaatcca ttcatccaga ttccagaatt
    36661 catggtcaat acttgcatcg tgtctttgag cggttaatga aagatcacac gcaagaaccg
    36721 tttgataata agttaaaaca agcaatctac cataccaatc aagaaagttt ttttcagcag
    36781 gtttaccaag ataatgccga ggctgagtac agtttagcta tactagaaga tattgttaga
    36841 tcaacagcac ctatcttgca acttaaccaa aacataaagg tcattgatca agaaaagaac
    36901 tttcatctgg atatgggaaa tgagatatta gtccacggga tcattgatcg tattgaccag
    36961 ctgagcgacg gtagcttggg cattgttgac tataaatcaa gcgcgaatca atttgatatt
    37021 gggacctttt ataatgggtt gagtccacaa ctagtgactt acctcgcagc cttaaaacag
    37081 atcgcaccgc acgatataaa ccaattattt ggggctatgt accttcattt gcaagatcct
    37141 aaattggatc tagtaacatt taaacaaatt gataacacat tagtggagag tatctataaa
    37201 gcgttgacct ataaaggtat tttttcagaa gtcgaaaaag agcatctatc tactggtgct
    37261 taccaaacca aaaatgctct ttattccaat gacgaattgg aaacactttt aaattataac
    37321 aagtacctct atcttaaagc tgctaaacac attaaaaagg gacatttttt gattaatcct
    37381 tatacaagcg atggtaagac agttcaagga gatcaattaa aagccattac ccgttttgaa
    37441 gcagatcttg acatggcaca ggcaaggcga ctagtgactc tccctgctaa ggagaaaaaa
    37501 gagtgctttt taacattaat gagaaaggag agccacttgt gatttctttt gccccatttt
    37561 taagccccga agctattaaa catttacaag aaaacgaaag gtgcagtgat cagtctcaaa
    37621 aacgcacagc tcaacaaatt gaagcaattt atactagtgg ccaaaatata cttgtatcag
    37681 cttctgctgg ttcaggaaaa acctttgtaa tggtcgaacg catacttgat aaaattttga
    37741 gaggtgtttc aattgatcgg ctttttatct caacctttac tgttaaagca gctacagaac
    37801 tgcgtgaacg gattgaaaac aaattatact cacaaattgc tcaaactaca gattttcaaa
    37861 tgaaagttta tttaacagaa caattgcaat ctcttggtca agctgatatt ggtactatgg
    37921 atgcttttgc acagaaagta gtaagtcgct atggttatag cattggcatt tcatcccaat
    37981 ttcgtatcat gcaggataaa gcagaacaag atgttttaaa gcaagaggtg tttagcaaac
    38041 tctttagtga gtttatgaat caaaaagagg caccggtgtt tagggctctt gtgaaaaatt
    38101 tttctggtaa ctgtaaagac acttcagctt ttagagagtt agtttatact tgttattctt
    38161 ttagccaatc gacagaaaat ccaaaaatat ggttgcaaga aaattttcta agcgctgcta
    38221 aaacttacca aagacttgaa gatatcccgg atcatgatat tgaactctta cttttggcaa
    38281 tgcaagacac tgcaaatcag ctaagagatg tgactgatat ggaagattat ggacagctga
    38341 ctaaggcagg tagccgatct gctaaataca ctaaacactt aacgatcata gaaaagttgt
    38401 ctgattgggt gcgtgatttt aaatgtttgt atggaaaagc cggattggat cggttgatca
    38461 gagatgtgac aggccttata ccatctggga atgatgttac agtctcgaag gtaaaatacc
    38521 ctgtttttaa gaccttgcat caaaaattaa aacaatttag gcatttagaa acaattttaa
    38581 tgtatcagaa agactgtttt cccttattgg aacagttaca agattttgtg cttgcgtttt
    38641 cagaagctta tttagctgtc aaaatacaag aaagtgcttt tgaattttca gatattacac
    38701 actttgcaat caaaatttta gaggaaaata cggatattcg ccaatcctat cagcaacact
    38761 atcatgaggt gatggttgat gaatatcaag ataacaatca tatgcaagag cgactcctga
    38821 ccttactatc gaacggtcat aatcgcttta tggtaggaga tatcaaacaa tcgatctatc
    38881 gatttcggca agccgatcct cagattttta atcaaaagtt tagagactat caaaaaaaaa
    38941 ctgagcaggg gaaagtgatt ttactcaaag aaaactttcg tagccaatca gaggtgttaa
    39001 atgtcagcaa tgctgttttt agtcacttaa tggacgaatc agtaggagac gtcttatacg
    39061 atgagcaaca tcagttaata gcaggtagtc atgctcaaac agtcccctat ctagaccgtc
    39121 gtgctcagtt attgctatat aatagcgata aagatgatgg caacgcccct tcagatagtg
    39181 agggtatttc atttagtgag gttacaattg ttgccaaaga aattattaag cttcacaatg
    39241 ataagggtgt cccttttgaa gacattacgt tactcgtttc ttcaagaaca agaaatgata
    39301 tcatttctca tacattcaat caatatggta ttcctatagt aacagatggt gggcagcaaa
    39361 actatcttaa atctgttgaa gtgatggtta tgttagatac attacgcacc attaataacc
    39421 caagaaatga ttatgccctt gtggctttac tgcgctcacc gatgtttgcc tttgatgagg
    39481 atgatttagc aagaatagca cttcaaaaag acaatgagct agataaagat tgcctatatg
    39541 acaagataca aagggctgtg attggaagag gtgctcatcc tgaattgatt cacgatacct
    39601 tgcttggcaa gttaaatatt tttttaaaga cgttgaaaag ttggcgtcga tacgctaagc
    39661 tagggtcgtt gtatgacttg atttggaaaa tttttaatga tcgtttttat tttgattttg
    39721 tagctagtca agcaaaagca gaacaagcac aagctaatct atacgcatta gctctacgtg
    39781 ctaatcagtt tgaaaaatcg ggctataaag ggctatactg ttttattaaa atgattgata
    39841 aggtacttga gacgcaaaat gacttagcag atgtggaagt ggctgctcct aaacaagctg
    39901 ttaatttaat gaccattcac aagtctaaag gtttacaatt tccgtatgta tttatcctta
    39961 attgtgacaa gcgcttctca atgacagata ttcataaatc atttattctg aatcggcagc
    40021 acggtatcgg tatcaagtac cttgcagata tcaaaggttt acttggtgaa acaacactca
    40081 attctgttaa agtaagcatg gaaaccttac cttatcaatt gaacaaacaa gagttgcgct
    40141 tagcaacttt atcagaacaa atgcgcttat tgtatgttgc tatgacacga gctgaaaaaa
    40201 aagtttattt tattggtaaa gctagtaaga gcaaaagtca agatatcaca gatcctaaaa
    40261 agttaggcaa acttttgccg ctggctttac gagaacagtt attgacattc caagattggc
    40321 tattagcaat agcagatata ttttcaactg aagatcttta ttttgatatt cgctttattg
    40381 aagatagtga tttgacacaa gagtcagtcg gacgacttca aacaccacag ttattaaatc
    40441 cagatgatct taaagataat cgtcaatcag aaacaattgc acgggcttta gatatgttag
    40501 aagcagtgtc tcaattgaat gccaattatg aagcagctat tcatttgcca acagttcgaa
    40561 cgcctagcca acttaaggca gcttacgagc ctttattaga acccattggt gtagatatta
    40621 tagagaaatc ttctcgatcg ctatctgatt ttactttgcc acatttttca aaaaaagcaa
    40681 aagttgaagc aagtcatatt ggatcagctc ttcatcagtt gatgcaggtg ctccctttgt
    40741 caaaaccgat aaatcaacaa acgcttttag acgctttaag aggaattgat agtaacgaag
    40801 aggtaaaaac agctcttgat ctcaaaaaaa tagagtcgtt cttttgtgat acaagcctag
    40861 gccaattttt tcagacttac caaaaacact tgtatcgaga agcaccattt gctattttaa
    40921 aagttgaccc tattagtcaa gaagaatatg tcctacgtgg tattatagat gcctactttt
    40981 tgtttgatga tcatattgta ttagtggact ataaaacaga taaatacaag cagcccattg
    41041 agttaaaaaa gcgttaccaa caacagttgg agttatatgc agaagctctc actcaaacgt
    41101 ataaacttcc tgtgactaag cgctatcttg ttttaatggg aggtggaaag ccagaaattg
    41161 tcgaagttta aggttgttgt gacacagggg tgttttgcaa atgataatag tagagttgag
    41221 gattttacga aatgcttgaa aagctattga cctttgaata ataatacaat ataataagtt
    41281 ttattagcga caaaaaggaa taaatatact atgaatttta aaaaaataag atttggtttt
    41341 ttgctttgcc tcctacttta tcctttagca gcttgtaaca agtctgaaca acttaatcac
    41401 cacgaaagaa ttaaaaaaac aagaaaatta gtcgttgctg taagccctga ttatgctcct
    41461 tttgaattta aagctttagt taatggaaaa gatactattg ttggagcaga tgttcaatta
    41521 gctcaggcta ttgctgatga attagacgtt gatcttgagc tttcaccaat gagttttgat
    41581 aatgttttgt ctagtttaca gactggtaaa gctgatcttg ctatttcagg aatctcacat
    41641 actaaagaaa gagctaaagt atatgatttt tcaattcctt actatcaggc agaaaacgct
    41701 atagtgatga gagcatctga tgctaaagtg accaaaaata ttagtgacct aagcggtaag
    41761 aaagtagccg ctcaaaaagg tagtatcgag gaaggtttag ttaaaataca attaccaaag
    41821 gccaatctga tttctttgac tgctatggga gaagccatta atgaactaaa agcaggacaa
    41881 gtctatgcag ttaccttaga aacacctgta gctgctggtt ttttagccca acataaggat
    41941 ctgactttag caccctttag cttaaaaacc agtggtggag atgccaaagc agtggccctt
    42001 cctaaaaata gtggtgactt aaccaaagcc gttaataagg ttattgctaa gttagatgag
    42061 caagaacgct acaagtcatt tattgcagag acaatagcac taacgaaaaa tactatgaag
    42121 taataaggtt aataaaaact ttattagtat ccgttggaaa agtgtttgga ataaacaata
    42181 aaagaggttt
//
LOCUS       DAUNLR010000012        40958 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUNLR010000012 DAUNLR010000000
VERSION     DAUNLR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40958
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.012"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..201)
                     /locus_tag="VLL59_000595"
     CDS             complement(<1..201)
                     /locus_tag="VLL59_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HER6508741.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIK"
     gene            complement(270..341)
                     /gene="shp3"
                     /locus_tag="VLL59_000596"
     CDS             complement(270..341)
                     /gene="shp3"
                     /locus_tag="VLL59_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HER6508742.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            421..1272
                     /gene="rgg3"
                     /locus_tag="VLL59_000597"
     CDS             421..1272
                     /gene="rgg3"
                     /locus_tag="VLL59_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HER6508743.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1525..5064)
                     /gene="smc"
                     /locus_tag="VLL59_000598"
     CDS             complement(1525..5064)
                     /gene="smc"
                     /locus_tag="VLL59_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HER6508744.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAVLQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQATLLELTKLMADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGTNRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5065..5757)
                     /locus_tag="VLL59_000599"
     CDS             complement(5065..5757)
                     /locus_tag="VLL59_000599"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HER6508745.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6200..7009)
                     /locus_tag="VLL59_000600"
     CDS             complement(6200..7009)
                     /locus_tag="VLL59_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HER6508746.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(7013..8365)
                     /gene="vicK"
                     /locus_tag="VLL59_000601"
     CDS             complement(7013..8365)
                     /gene="vicK"
                     /locus_tag="VLL59_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HER6508747.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8358..9068)
                     /locus_tag="VLL59_000602"
     CDS             complement(8358..9068)
                     /locus_tag="VLL59_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6508748.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9230..10264)
                     /locus_tag="VLL59_000603"
     CDS             complement(9230..10264)
                     /locus_tag="VLL59_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HER6508749.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     SIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10320..11567)
                     /locus_tag="VLL59_000604"
     CDS             complement(10320..11567)
                     /locus_tag="VLL59_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HER6508750.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLKKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDYL
                     PLRDNGKINREVLLNKIPKQWLS"
     gene            complement(11524..12672)
                     /locus_tag="VLL59_000605"
     CDS             complement(11524..12672)
                     /locus_tag="VLL59_000605"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HER6508751.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNTVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAAISVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPHLSSKVLSKVPSILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVVKASQVLLAKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13067..13216)
                     /locus_tag="VLL59_000606"
     CDS             complement(13067..13216)
                     /locus_tag="VLL59_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HER6508752.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(13417..14202)
                     /locus_tag="VLL59_000607"
     CDS             complement(13417..14202)
                     /locus_tag="VLL59_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508753.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESVGS"
     gene            complement(14204..15022)
                     /locus_tag="VLL59_000608"
     CDS             complement(14204..15022)
                     /locus_tag="VLL59_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HER6508754.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLVVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(15024..16016)
                     /locus_tag="VLL59_000609"
     CDS             complement(15024..16016)
                     /locus_tag="VLL59_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HER6508755.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELRPGQEQVVSQFMGLPDII
                     VERHELSLDIQYDSSRYQTADIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(16157..18100)
                     /gene="thrS"
                     /locus_tag="VLL59_000610"
     CDS             complement(16157..18100)
                     /gene="thrS"
                     /locus_tag="VLL59_000610"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HER6508756.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(18522..19856)
                     /locus_tag="VLL59_000611"
     CDS             complement(18522..19856)
                     /locus_tag="VLL59_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HER6508757.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLR
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19858..20856)
                     /locus_tag="VLL59_000612"
     CDS             complement(19858..20856)
                     /locus_tag="VLL59_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HER6508758.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKED
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20987..21988)
                     /gene="ccpA"
                     /locus_tag="VLL59_000613"
     CDS             complement(20987..21988)
                     /gene="ccpA"
                     /locus_tag="VLL59_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HER6508759.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22162..23247
                     /locus_tag="VLL59_000614"
     CDS             22162..23247
                     /locus_tag="VLL59_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HER6508760.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTHYVQGMRLVKSADEINNMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23296..23961
                     /locus_tag="VLL59_000615"
     CDS             23296..23961
                     /locus_tag="VLL59_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HER6508761.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEDDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23972..24349
                     /locus_tag="VLL59_000616"
     CDS             23972..24349
                     /locus_tag="VLL59_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HER6508762.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24494..25420
                     /locus_tag="VLL59_000617"
     CDS             24494..25420
                     /locus_tag="VLL59_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HER6508763.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFDDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25631..26314
                     /locus_tag="VLL59_000618"
     CDS             25631..26314
                     /locus_tag="VLL59_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HER6508764.1"
                     /translation="MEWFKLIGIVIIVLGFILKFDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQHVQSLTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDTEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26314..27240
                     /locus_tag="VLL59_000619"
     CDS             26314..27240
                     /locus_tag="VLL59_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 family protein"
                     /protein_id="HER6508765.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGVGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27291..27938
                     /gene="pcp"
                     /locus_tag="VLL59_000620"
     CDS             27291..27938
                     /gene="pcp"
                     /locus_tag="VLL59_000620"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HER6508766.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28057..28776)
                     /locus_tag="VLL59_000621"
     CDS             complement(28057..28776)
                     /locus_tag="VLL59_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HER6508767.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28782..29249)
                     /gene="smpB"
                     /locus_tag="VLL59_000622"
     CDS             complement(28782..29249)
                     /gene="smpB"
                     /locus_tag="VLL59_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HER6508768.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGTG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHDYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29252..31585)
                     /gene="rnr"
                     /locus_tag="VLL59_000623"
     CDS             complement(29252..31585)
                     /gene="rnr"
                     /locus_tag="VLL59_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HER6508769.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYSQPSQEKRDHFTQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVASVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31679..31915)
                     /gene="secG"
                     /locus_tag="VLL59_000624"
     CDS             complement(31679..31915)
                     /gene="secG"
                     /locus_tag="VLL59_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HER6508770.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31961..32107)
                     /gene="rpmG"
                     /locus_tag="VLL59_000625"
     CDS             complement(31961..32107)
                     /gene="rpmG"
                     /locus_tag="VLL59_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HER6508771.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32104..33297)
                     /locus_tag="VLL59_000626"
     CDS             complement(32104..33297)
                     /locus_tag="VLL59_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HER6508772.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPVRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33419..34921)
                     /locus_tag="VLL59_000627"
     CDS             complement(33419..34921)
                     /locus_tag="VLL59_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HER6508773.1"
                     /translation="MTTMTIAKGSQPIALQLGMLNRHGLIVGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISELGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DYASDYSSHYGNIAKQSIGAIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFASKYSQFIDRESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKE
                     QAAAEKASRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35111..35704)
                     /locus_tag="VLL59_000628"
     CDS             complement(35111..35704)
                     /locus_tag="VLL59_000628"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HER6508774.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQVIKEELAAKRDHLA
                     QSQAIFFMDIPLLIELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLSLANPR"
     gene            complement(35701..36528)
                     /gene="mutM"
                     /locus_tag="VLL59_000629"
     CDS             complement(35701..36528)
                     /gene="mutM"
                     /locus_tag="VLL59_000629"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HER6508775.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVSDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(36700..37566)
                     /gene="rgg2"
                     /locus_tag="VLL59_000630"
     CDS             complement(36700..37566)
                     /gene="rgg2"
                     /locus_tag="VLL59_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HER6508776.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKTLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37655..37723
                     /gene="shp2"
                     /locus_tag="VLL59_000631"
     CDS             37655..37723
                     /gene="shp2"
                     /locus_tag="VLL59_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HER6508777.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38637..38906
                     /gene="stcA"
                     /locus_tag="VLL59_000632"
     CDS             38637..38906
                     /gene="stcA"
                     /locus_tag="VLL59_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HER6508778.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39254..39685)
                     /locus_tag="VLL59_000633"
     CDS             complement(39254..39685)
                     /locus_tag="VLL59_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HER6508779.1"
                     /translation="MEVSSEVAVSASQPEELHRLPEEDNNKLSRVAKEVVTEPRLNNP
                     FLLSKKVLSLEDDAAILNHLEEDRNVNKLFLEPVTAEAKREINFHPSDQQVTAKVKES
                     SDFHQKQHQTGITYGDDTLADLTHHLLHSDGVLPSLNDKSA"
     gene            complement(39730..40800)
                     /locus_tag="VLL59_000634"
     CDS             complement(39730..40800)
                     /locus_tag="VLL59_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508780.1"
                     /translation="MMMLRDVKVKTSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGLAGIERMTTLIKNVGALLTTGGSGAFPDNIK
                     VSINPKGRQATITYGDGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNQDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
BASE COUNT        12339 a         8714 c         7176 g        12729 t
ORIGIN      
        1 tttgatttta tcttctaaac acactgagtc taccaaaatt tttttatgtt tatattcatc
       61 cagaactcct atgttgtgat ttagatattc aaataattca tctgatatag aatgttcaac
      121 tggattacca agcaatgcag aatacataaa tttcatcctc ctacgtttaa ttagtttact
      181 actaacataa agtacaagca ttacacagag ctaaccatta cctataagtc tttagagtat
      241 ctaaagactt aggtgtacac ctaagtaact tacccaccaa caataatgat aatatccatt
      301 gctaaaatta aaatcggcaa aaattttgaa attttcttca taagcggact tcctttcagt
      361 ttttatttat tgtacaataa aaaaaaacgg aattgatttt tgttgggaaa gtgggaaaat
      421 atgaaatcaa aacttggtgc cacacttaga aaagttcgaa aaggaaagca aattagtctg
      481 tgcttcgtgg cagatgaaca cctttcaaaa tcacaaatct ctcgttttga gcgcggggag
      541 tcagagatat cgtgtatccg actgatcaat attctagaca aattacacat tactttggat
      601 gagtttctta ttttacatga tgaagactat accaattccg aaacatttgc taacctggta
      661 cagtatattc gtaagcaata ttcatcacaa aatattaata atatagcatg tttactttcc
      721 gacacttctg attacactct gaattctttt gagaaaacaa tggtaaagtc cattttacac
      781 acaatggatt caagcatcat tccatcagat gatgaattac ttcaactaac agattatctc
      841 tttaaagttg aaaaatgggg ctactatgaa atccttttgt tgggtaactg tgtacgaaca
      901 attaactaca actcctactt cctattgaca aaggagatgt taaataatta catttactct
      961 tcacggaaca aaactaataa acgaattgtc actcagcttg ctataaattg tttcattctt
     1021 agtatcaata aggaggaatt ttctaattgc tcctatttaa ttgatgagat aaaaaccttg
     1081 ttagataatg aattaaactt ctatgaacag acagtttttc tctatgcaac aggttacttt
     1141 gagtttaagc gccaattaga aactggagtt gaaaagatga aacaagccat acaagttctt
     1201 gatattttaa atgaagacaa gttaaaatta cattacgctg accattttga taaactagtc
     1261 aacaaagatt aagtaaaatc attctttacc ttttaacgaa acgccaatca agggtgtctc
     1321 aataaaaaat catctactct gacaactttt ctcttttacc tatcgacagc taaaaagcct
     1381 tggaaactgc tatttccaag gctttctttg tactctattg tatcaattag cttattccga
     1441 tttctgttgc tattagttta atcatgaaat ctcctaactt atggccgaac atccaaaaaa
     1501 acagaaggaa ctcccttctg ttttttaatt ggtcatctct tgagcttctt ttaattttac
     1561 agatacaatt ttagagaccc ccgattcctg catggtaatt ccataaatac tatctgctgc
     1621 agccattgtt cctttacgat gggtcacgac aataaattga ctatctttgt caaagcgatt
     1681 gaggaaatcc ccaaagcgct taacatttgc ttcatcaaga gccgcttcta cctcatctaa
     1741 aatcacaaac ggaatcgttt taacacgtat aatagcaaac aataaagcca gtgctgacaa
     1801 agctttttct ccgcctgaca tcaagttaag agattgaatt ttcttaccag gaggctgcac
     1861 agaaatctct ataccagcag acaagaggtc tgtttccgtt aaaaccaaat cagcagaacc
     1921 cccaccaaac atctgagtaa aggtttcttt aaaacttttt tgaattgcct caaaagtcac
     1981 tttgaaacga gccttcactt cgctatccat actattaata gtctctagca aaagattttt
     2041 agcttttgtc agatctgtct tttgacttgt taaaaaagtc aaacgctcat gcacttcctc
     2101 atactgatta atagcatcac tattaattgg tcctagtgca cgaatagtct tttgtaaatg
     2161 gtgtaatttt tctttggcac tttctaagtg atcaatacta tttgttacct cctttgcgtc
     2221 tgctagtgtc atttgaaaat cttctgataa acttttagca taggctcgta agcgattagc
     2281 cacttgctct aaatgtgtct ctaacttggt ttgacgacga ataaatgtgt catttttttc
     2341 gctttctttg gttatttttt ctgctgtttc ttctaagcgg gcctcatagt cctctatttc
     2401 aaatcttaat tggactaaac gtttttgagc accagactta tgctctgtgg catcttgtaa
     2461 ctgtttttgc cactggggta gtctttgaat gctgtcttga cttacgttat tgtttagtat
     2521 gctttcaagt ttgagaatat tttgctggca ttgcttcagc tgagttctta gacgagattg
     2581 attagcttgc tcaaatttct tttcattaag taaatctctt tcttgtaaac gagcttgaga
     2641 taaagcttgg tgaatgtttt gtgttttttg cctaatcaaa tctttgtttt ctttgatatc
     2701 atcaatatca caagttaagg catttttttt cttagcaata gctgttaatg cttcttcaat
     2761 acgagcttgc tctgccaata aagattcatc agaatgagtc gtctgacttt gatcaagggc
     2821 agctaacaaa gcctttgaat cttcttgttt ttcttgcaat tgctgataag ccatttgagc
     2881 tctttgttca gctaagcgtg cctggtcacc ggctaatttc aattgtgtca gttcttcttt
     2941 ttttgctatc aaatcgcttt gcaaggcagc tacttctttt tcagttattt ttaattgctc
     3001 aactaatcgc gttaattcct cactgatttg ttctaactct ggtttgataa aagttgtatt
     3061 gctttgtcta ttagttcctc ctgaaaaaga accacctggt cgtaattctg ttccatcaag
     3121 agtaacaatt cttaccttat atcctaataa gcgcgctgca atattagctt gatcaatagt
     3181 ttcaaagata gcagtactag ataaaaggtt ttggataata gctgaaagac tatcatcata
     3241 gcgaaccaat gattctgcag ttcccagata accttcacaa gtcgctaatt gacgatgata
     3301 gtgttctgac aatgatctag cctttatagt agttaaaggt aaaaaagttg ctcgtccttg
     3361 gcgatttttt ttcaaataag caattgctct ttttgctgca gcttcgtctg ttacaataat
     3421 atgctgacta ttagcaccta atgcaatttc aagagctgtt tggtaatcag aatcaaaaga
     3481 aaggtgttca ctgactgcac ctatgatccc tccaagcttt ttttgtgatt gaaggacagc
     3541 tcgtactccc gcatagaatt gactatgact tttttgaata gattctaagc tagccttacg
     3601 agcttctttt cctttttttt gatccaacaa gtcaaatagt ctttcttgat tcagttggta
     3661 atctctttct aattcctgaa cgcgtttatc accttcttga taattttgga gcaacatttc
     3721 gacttgctct ttttgagctt tataatgagc ttgagctttt tgagactcgt cattaagttg
     3781 atcaagctta gtaacaagta gctgatattc ttgagcctta tgttgacgag cctgtttttc
     3841 tttgtctaaa tgggctttta aagctgtcag ctgatttgat aaggccgcct ctttttgcat
     3901 caataataca aactcttctc ttagagtttc cattaattgg tcgggatcac ttgaaaaacg
     3961 ctctaatgca ttgctcaatt cgtttaactg ttgtttgaca tcacaaagtt gttgatcaat
     4021 atgcaataat tgttctgtac gctgcttttc ttctgcttga aaaccatcca attgttcttg
     4081 taactgttcg aggtgttttt tggcttctgc ctttttctct gcttcttggc cactttctag
     4141 cttaaccaat tcaatttgct tttccaagtc agccattagc ttggttaatt ctaataatgt
     4201 tgcttgggtt tgatctgact cttgactaag aacttgcttt ttttgcttga atttttggta
     4261 atcttcttcc atagattgac gcttagcgta ataagatgct aagtcttgtt gtaaaacagc
     4321 taaagcttca gtatctttag tctgtctttc ttgagctata tcaatatctt tgactagaat
     4381 atctagttgt agttgcttac gattggcatc aagttctaaa aattgtttag ctactttagc
     4441 ttgcttttca agtggggcca actgcgtgtc tagctcataa ataatatcct ctagacggtc
     4501 taaattatct tgagtttgat ttaatttaat ctgagtttct tttttacgtg ttttatattt
     4561 taaaacacca gctgcttctt caaaaatggc gcgtctttct tcaggtttac tattgaaaat
     4621 ttcctctaca cgaccttgag aaataatgga gaaagaatca cgaccaagcc ctgtatccat
     4681 aaacaaatca tgaatatcac ggagccttac cttgcgacca tcaatcagat agtcactatc
     4741 tccatttcgg taaatatgcc tttcgacacg gatttctttc ttggcagttt ttataaaatg
     4801 atcggaatta tcaagaacaa ccgctacctt agcatagttt agaggattac ggttttgtgt
     4861 cccagcaaaa atgacatctg gcatcttgcc cccacgcaga tttttagcac ttgattctcc
     4921 taaagcccaa cgtaaacttt ctgtaatatt acttttacct gaaccatttg gtcctacgac
     4981 tgcagttact cccttatcaa attcaatttt agtcttgtcc gcaaaggact tgaacccttc
     5041 caactcaatt tcttttaaaa acatctaaac ctcactaagt tgggcaaggg catttttagc
     5101 agcatcttgc tccgctaatt ttttagactt acctaaacct ttactaagga cagcaccatt
     5161 aacaactatc gatacctcaa attgtttagc gtgggcaggt cctttctcac taatgacttg
     5221 ataatcaata gccacatcac cttttgtttg caaaaactct tgaagacaag ttttatagtc
     5281 tttaaccctt tcaaaattcc ctttttccac ctgaggaatc atgacttgtt tcaagaagcg
     5341 acgtactgca tcaatcccct tatctaataa aagagcacct aaaaaggctt caaataagtc
     5401 tcctaaaata gtatcacgac ggcgaccacc tgacttttcc tcaccttttc ctagtttgat
     5461 ataagcgtca aaagaacaaa atcgtgaaaa acctgccaag ctttcctcac gtacaatcat
     5521 ggaacgtaac ttagacatat ctccttctgt ctttttagga tactttgcaa ataaatactc
     5581 tgaaataatc aattgtagaa cagcgtctcc taaaaattcc aagcgttcat tatgtgaaac
     5641 gtttaggaga cgatgctcgt tagcgtaaga ggtgtgggta aaagctgttt ctagtaaagt
     5701 caaatcatta aattgaatat caaaagatgt tgagagtaac tcttcaagct gtttcataaa
     5761 aaatcccttt catatttgtc agtagacctt atttagtata ccaaaaatcc acctagaaaa
     5821 ccgactctaa gtggattttt cgtgatttat taaacatctt aaatacccgt caaaggaaac
     5881 tttctcatac aatcaaaaga ctctacacta tctgagggga atttcccact acagtcccac
     5941 tacagatagt atagagctat tttgttttta gtctgaacaa ctaaaaaact accttatctt
     6001 tacaatcctc aacacctttg ataaatagat cagacaagcc aaaactacag gctaatttaa
     6061 gtctattgat gctctaaaag atgaccaatg agagttcatt gaactcagaa gacaatacgc
     6121 tttaagacat caaaaaatag ccctgactgg tatatcacca atcagcgcta ctttgcatat
     6181 tctcttttag tttcttatct caaatatcag ttaatggaca agcagtatct ggagaggtat
     6241 catggaccgt aaagtctgta cctactgcta aatctgccat agccagttga ttgaccatcg
     6301 tcatatgcgc taactctttg atgttatttt ctttactcag atgacctagg tatatttttt
     6361 tggtattgta ccccaggctt ctaatcatgg ctcccgctcc atcttcattt gataaatgtc
     6421 ctaaatcaga taaaatacgc tgcttcaagc tccaaggata agagcctgat ctcaaaattt
     6481 caatatcatg attggattca atcaagtagc catctgcatt ttcaataata cctgtcatcc
     6541 tatcactgac atatcctgta tctgtcaaca tcacaaaaga cttattatct ttcataatcc
     6601 gataaaattg aggatcaata gcgtcatgac tgactccaaa actttcgata tcaacatctc
     6661 caaaggtcaa aactttatcc ctttggaaaa tatgtttttg tgaggcatca agcttaccta
     6721 gcatattgca ctcatccatc agctgccatg ttttttcatt agcatagata tccaaatggt
     6781 atttgcgggc cataacgcct acacccttaa tatggtcaga gtgctcatgg gtaatcaaaa
     6841 tagcatccaa atcctcaggt ttgcggtcaa tttcagcaag aagactggta attttcttac
     6901 cagtaagccc tgcatcaatc aataagcgtt ttttaggtgt ttctaaataa aaacaatttc
     6961 ctgtggaccc agatgctaaa atactatatt taaaaccact ctcattcatt gattagtcta
     7021 catcttcctc ccattcttca tagatggctg catctttttc ataaggcaag acaatagtaa
     7081 aggtcgatcc tttaccatag tcactcttag cccagataaa gccatggtgc tgcttgatga
     7141 tttctttagc aatggcaagg cctagaccgg tccctccttg ggcacgactt cttgccttgt
     7201 ctacacgata gaaccgatca aaaataagag gcaaatctgt tttaggaata cctagtcctt
     7261 ggtctgaaat ggaaataatt aattgggtat ctgttgtttt catacggact gtaatttttc
     7321 caccatctgg agaatactta atggcattgt tcaaaatatt ctcgataacc tgtgtcattt
     7381 tatcattatc aatttcaagc cagacagagg taatagggta atctcttaca atttcataga
     7441 cttttcctgt acctgtatgc tgatttttaa ccaaatcaaa tctgtttaaa atagaagtta
     7501 taaaagcagt aaaattagtc atctctactg ctaattgggt tacttgatta tcaatccgag
     7561 acaggtttaa aagatctgaa atcatacgca tcatccgatt agtttcatca agagaaactt
     7621 ttatgaaact tggagcaata tcttctttaa gtgcaccttc atcaagagcc tccaagtagg
     7681 atttaaccga agttaaaggg gtccttaatt catgacttac attagagaca aaaagacggc
     7741 gttcacgttc ttctttttct tgttctgtgg tgtcatggag caccacaacc aagcccgaaa
     7801 taaaaccact ctctctccta ttcaacgcaa agcgcaagcg taatgagaca aactcaccca
     7861 tatcatttcg gctattaaca gttaccactg gtgttttgga taccaaatca cggtaagtat
     7921 atgaagtatc accttctaac aaatctgtaa tgtttttctt tagtgcctct tctttactta
     7981 aatttaattg cttgcgagct gtctcgttaa tcatgatgat tttaccagac cggtctgtag
     8041 caagtacacc atctgacata taagccaaaa tacttgccaa gcgatttttt tcttgggcaa
     8101 gattttcatg cgtcaagcga aaaacatctg acaggtcatt taactggtct gaaagctcca
     8161 ttaactcaat gtctgctttt tcgtcgatta tatcagtata gcgaccatta atcaagtctc
     8221 ggattttatg gctcatcatc cgaataatac gtgcatttcg gtaatcacgc accgcaagat
     8281 ggataaagta aaaagcaaca aaaacaagta agataaggat cgctaattca aatgtggata
     8341 agtttccaat gatatctcta gtcataagat ttcatgtagt acccaacacc acgtcttgtt
     8401 aaaatatact caggacgact tggtgtgtct tcaatttttt cacggagacg acgaacagtc
     8461 acatcaaccg tgcgcacatc gccaaaataa tcatatcccc aaacaatttc caataagtgt
     8521 tctcgtgtca tcacctgacc catatggtta gctagatgat gcaatagttc aaattcacga
     8581 tgggtcaact ctacctcttg accatgtttt ttagcaacaa acgcatctgg taaaatctgt
     8641 aaattaccaa tggttagttc ctgtgtacct gaagaagcat tttcttctgc aacagccgtt
     8701 tcaatagttt cggtacgacg cagatgagcc ttgacacgcg ccagcaattc ccgattagaa
     8761 aagggcttgg tcacgtaatc atcagcccca atttcaagtc caataacctt gtcaaactca
     8821 ctatctttag ccgacaacat aataatcggg acatgactgg ttttacgaat ttccttggct
     8881 acttcaagac cgtccaactc agggagcatc aaatcaagaa taattaaatc tggcttttct
     8941 tcttcaaaaa ttgttaccgc ttcgcgtcca tcaaaagctg taacaatgtc ataaccttct
     9001 tttgtcaaat taaacttaat aatgtcagaa atcggttttt catcatccac aataagtatt
     9061 tttttcatgt ctatacctca gaaagttctt gtaattgata ttacaatttg tgatttttgt
     9121 ggttagtaaa aaatcacaaa actatatttt tctaaattat ttctacctga ttataccaaa
     9181 aattcagcct aattgacaat gacgactacc gttacaaata gagtactttc taaaaccaac
     9241 cctttatagg atgaatttgg cgtttgaatt gcttagcaga ttttttgact ctggcaaaac
     9301 tactcttgtt gtggtaagca aaaagtcctt tggcattaaa ataagagaac ataaagtcat
     9361 ctttttgagc tctaaaccac tggcgaaata ctctttttgg cgatcgaaat cctttaaggg
     9421 tgtctcttct aaactgagga tcgtgacggc taatcggatc aacatctaaa tcccaatgtc
     9481 taggaccatc tgtgccatag ttaaaagatg caccattgac aattcctttt tcggtcacta
     9541 cttctgcatc aacttcatta agaaaaaagc ctgtgctatc tagaataaat tcggtatgaa
     9601 accaaagaag tacttttata ttataggaaa cttcttgact tggaaaaatg actttattat
     9661 cttcaaatct tagtttatta tgtaacctgg cagaatccat caaggtataa tctggtgctt
     9721 gccgccacaa acaaggccct tttttagacc tcaaaaaaag ggccagagct tgggcgtctg
     9781 tcatctcaat cattttataa tggtttctga tagattgagc ttgttgacta gagatgacat
     9841 aacgaaattg atgcaaacgc ttttcaagct cacctgcttg gcttagtgtt ttgccaggaa
     9901 aagcttgatc aactaagcta gccaactctt tccaaaacat atgatctggc aatagagatg
     9961 gatggaatcg ggtgagtagc gtttgagttt catgcaactg accacttagc tcaaatggca
    10021 tctctaccaa atcaagaaga aacgttagta actgcttagc tgattggttt tctttttcaa
    10081 taggccatat tacccagaaa gttggagaac caagtcgatt atcaatgata gactctttag
    10141 ctatagcacg aaatgcttgg tttgataaac ctgcgttttg atagcatttc aaggcctgat
    10201 agcgatctaa gatagcttgt ttcatggcct tctcctcatc ttttttgacc atattataac
    10261 acatctaaag ctgaatcgtc acttgtatct cactataagc aaaacgaaac ctgaagtcgt
    10321 taactaagcc actgtttggg tattttattt aaaagaactt ctcgattaat tttaccatta
    10381 tctcttaaag gcaaataatc aatcacaaga tagtacttgg gaagttgtcc agagtttaaa
    10441 taaagagcta aaaagtcttt aataggtgct aggcaatcct tcttagtcaa aactaatact
    10501 aatattaggg tttcgttttc tccttttcct atctttaaag cgtgcgcttc tttgacgttt
    10561 ggcgcttggt gagcgagttc aactaggcta ggcaggtggc atttcactcc tcgttgatta
    10621 acccagtcat cttgtcgccc ttctaaaatt aaacccgctg ggctcatttt tcctaagtct
    10681 gagacactgt atggttgtga cattccttct acactataag gagtctctac aaaaatttcc
    10741 ttatctttga aactgataga cacatcagga aagggctgtc ctaccaaacc attaattttg
    10801 acagcagctc tgccattaca ccacgttata aaagataatt cactagcccc gtagaaaatg
    10861 acaatttcaa gctgaggaaa ttttttgtaa taatgtctta gtaattcttg tgatatcatt
    10921 tgcgaagagg tcaataagtg agtcgcagtc atgttgttct tagtcaaata aggtagcaag
    10981 cgatttaggt aggtcggtaa aaggtaaagg tgactcacct tttttgcttg ccataagctt
    11041 aaccacgttt tcaaagacag cttttggctt aaaaccagac atcccccggc ccatagttga
    11101 gctaatgcta agttaagatt gccagtaaaa ctaaaactac catgtaagaa tagacaacta
    11161 ttaccagtca taccaaacac cttattttga taatcaaaaa gtctcgtcca agttgataga
    11221 caacgccaaa ataattttgc tttgccagtt gttcccgaac tcaaaacagc aaaatcagct
    11281 tttttaagaa gctcaccatc gacgtgtttt atttgctgct gaaatgtacc tgagatatta
    11341 gggtgtaaaa tgataggaca actgccttct tttaatcctc gtaaaaaaga gagtaactga
    11401 ttaagatagc gactatgact gatgatatat ggtacactgt cttttattgt ctgatccttt
    11461 attaaaaccg cctgccatag ctcttgataa gtcaagctta tctgatcggc tacgatagct
    11521 tttttatttg ggcattgctt tgcccaatat tctagctttg tcagcatgac taaactcctt
    11581 atgatatttt agtaaaacag caaacccttg gccaccagct gctgctatag cagctattcc
    11641 atagcgtcca tttttaatct ctaaagccct cattaagtgc aatattataa tggctgctga
    11701 ggcaccatag ggatgaccat aagctaatgc accaccaaat atattatagc ggtccaataa
    11761 atctggataa tgggtttcaa atagaccatc aataacggca aaggcttcgt tccattcaat
    11821 cgctgtcata tctgccatcc ctagaccatg ttttgccaaa aggacttgac tagccttaac
    11881 caccattaaa gggctacgct gtgggtctcc tgctacttct accacatcga tcagtttaaa
    11941 agctgaaggc tgactactta gctgtaaaaa ggcagcagca tcatgggtga ggcaggcatt
    12001 ggctgcacta atcacgtgat cttctcctaa gatagagggt acctttgaca acaccttact
    12061 tgacaagtgc ggtcgaatac cttgatcact ggctcctggc aggtctagaa taagatcagc
    12121 taacagggct tgctcctggc aataactagc cttttgatga cttctcaatg tccagtgatt
    12181 caaatactcc tttgtaaagc catgctctct tgccactcgt tctgcccctt caatcatcgc
    12241 aaaagggctg atactatctg gagaaaactg agctaccttg taggctcctt ggcgccaatc
    12301 agctgaagca tataccgatt caggttgtaa ggagctgctt tcaatccctc ccactaaaag
    12361 gttgcttgcc atacctgcct tgattttagc ataacccacg gaaatagctg caccagctga
    12421 tgcacactgc atatcaaccg tcaaagcaga gacagattct cctaaatgag aatacagggt
    12481 catcaagcgc ccaatattac cacccgttcc gacggtattg ccacaaatca cttggtcaat
    12541 gggaactgga tacttatttt gtaaagcgtt gatgagcttt gctccaagga tttctggttg
    12601 ttctttagca aattgtttcc ctactaaacc gataggggtt ctaaggcctg cagcaatata
    12661 aacatccgtc attatattga cctcctttat tttcgatgtc cttaaatggt tattatataa
    12721 ttatttctga tggttttctt ttttgaacta ataactgcta aaaatacacc taaattaatt
    12781 tagagaatct ctttagtctc gctagtgtgc catcaataaa atctataaaa ttctctaacg
    12841 tcattgaaat gtcaagtccc acaactattg tcgtagaagt cacttacttt gttgctttaa
    12901 cattcaaact gtaacctttg tttttgatac agggtgactt tattatactg gaaaaccatt
    12961 cctaagaaaa gaaaatctta tatagaataa agaattagac accataaaaa agctaagctg
    13021 tgacacttaa cttttttatg gtattgacaa accttgtctt tactatttat tgatagttaa
    13081 tgcctctaac taaaataaaa gccatgtctg tatcagcctg caaggcatct gctaagctgg
    13141 tatcgttact agatttgaca ggtctcataa aggcaaaaga tctcaaagtt ccataaacgt
    13201 tatctagcaa ttgcatgcaa ccacttgaaa tatatctgct tatgttattt taccgccctt
    13261 aatttagacc aatctgctga tgatggttcc aaccaatgcc tacgcttggt aaaccatcac
    13321 aaaaaaaagc agccgttttt acaacagctg ccttccttca ttatctaggt tttcatattc
    13381 tgacctaaac gattttcaat ttgtttaaga gtctctctag gaacctacac tttcataagc
    13441 atctaggccc catttccaaa gcttaagcga caaggccaaa accagtaacg acaccactac
    13501 caagcctcca atattaaaga gcaggtgttg acctgttaaa aaataagaag cagggtaata
    13561 agctgtaaaa gcaaagggaa tgataaaact gattaaccac cgcaaaaagg aatggtaaat
    13621 ggacataggg tacttagaaa agtcattgaa catgtaaaaa atatagataa ctgccccaga
    13681 ctgcttggtc caaaaagaaa tgctggcggt cgcaattttt aaagaggtgt aaatcaaggt
    13741 cgcaaaagga ataaccaaaa taaacaaaag caccttagga agagtccata cgatactacc
    13801 agccgtggtc actaataaga taaccccaac caataattca cccagggcat ccacttgaaa
    13861 ggtctcaact aaaacatgaa acaaaggact aattggtctg gtgaggtact tgtcaaattc
    13921 tcctttgcgg acaagccgtt gccctaaagc ccaaagattg tcaaaaaaga ggtgatcaat
    13981 tccctttgga atcaaagaaa agccataaat aaaggcaatt tgttcaaacg tccagccttc
    14041 taaagaaggg atatgttgga aaagtaccga taaaaagagc agattaagac cctgagtgag
    14101 aaaaacacct agcactccca ccacaaaatc aaccttgtat tccataattt gtttgaggta
    14161 ttgtttgata aaaatagcgt gcatacgtct caattttgcc atctcaccct ccttgaatcg
    14221 ttaaatggta ctgaaccttt ttccagatga cttgcgataa gactaccatc accagtaacc
    14281 aaaagatttg caaacttagg gccaccatta tctgactaag gctgtatttc ccaatgacaa
    14341 tcataactgg cgtgtaaacc aaagaggaaa acggtagaaa actaagcact atagaaacca
    14401 ttttaggaaa aaaagccaat ggaatcaaac tgcctgacat aaaggcaacc aaggcatttt
    14461 tcaataaatt agacccccaa aggtttttaa aaacaaatgc tgaaaagcca aaacaaatgt
    14521 tgaaataaaa attgattaaa aaagctaata aaaggctaac taaatacaga caactgctgg
    14581 ctaggacttg caagatagac agccccgcca tgactttaat accagataag accactaaaa
    14641 aaggaaagcc gacactcatt agcacaatcc agcgaaaacc aatttccata aagaggtaag
    14701 aggctgcaaa atgaactggt cgaagcaggc gcatgatgat agaaccatct ttcacttctt
    14761 cgccaatcat aaaggagctg tctgatttgg tcagtaaagt ggtcacaaaa ctcatgataa
    14821 tgtaaaaggt catgtcagac agagtaaaac cattgattaa ggattgctta gacgaatcaa
    14881 aaacagcctt ccagaggtaa taagccacaa aagcccccat gacatctcca atacgataca
    14941 aaaagaaatt aacgcgatag gttattaatt cctgaattcc tgcactgaga aagggtctat
    15001 aacgtttcca aaatgaccac atcttaaagc tcctttcggt agaaacgacg aacaatatcc
    15061 tcaatatcaa catcagtcat cttcaaatcc ctgaccgcaa aatcagccat ggttttttga
    15121 ataatgtccg ctgtttgata gcgcgaactg tcatattgaa tgtctaaact aagctcatgc
    15181 cgttccacta tgatgtcagg taagcccata aactgtgaga ccacctgctc ctgccctggc
    15241 ctcaactcaa aagacagact cttcattttt ccaaagcttt gctttaattg ggtcaccgtt
    15301 ccatcaaaga tttcttgccc tttatcaatc atgataatcc gatcacagag ctgttcaata
    15361 tcactcaaat catgggtcgt cagtaaaata gttgtctctt cttcttgatt aatttgagta
    15421 atggcacgcc gaatgttgtc cttcacagaa acatcaagtc caatcgttgg ttcatctaaa
    15481 aacaatactt taggattatg caacaaggaa gcagcaatat cagctcgcat ccgctgaccg
    15541 agtgataagg tccggacagg atccttaata aactcattca ggtccaaaac ctcatttaaa
    15601 aaatccatgc gcttgcgaaa ggctttttca ggcacatcgt aaatttcttt taaaacgaca
    15661 taggtctctt gcaaggccaa atcccaccat agttgtgttc gttgaccaaa aacagctcca
    15721 atgtctctca cataatcttg acgattatct tgtggaatct ttccgttaat gcgacagtaa
    15781 cctgatgtag gctttaaaat acctgttaac atcttaatcg ttgttgattt tcctgcacca
    15841 ttggctccaa taaaacctaa aatttgccct ttgggtacct caaaagataa gtccttaacc
    15901 gcctcaaaga tttctctttg gggatgaaca aaggacttca aggctccctt taatcctggc
    15961 tctttaatgg ttttggaaaa atttttttga aggtgggaca cttctatcat gaccatttac
    16021 cattcctcgt ttctgttatc gtcttatcac cgttactaaa caatttatta taacaccata
    16081 aaaaagacgg tgcaaccgtt tgcttaattt tttaagaaag aaaaagaagc ccataaggac
    16141 ctctttttgc cattgattaa gcttgtgcat ctggacgtga cttgcgagca atgtctgcca
    16201 agatgttttc cacaaattct tccacagatt cagtgtgagt cgccttacta ccatagcggc
    16261 gaacattgac tgatttgtct tccatttctt tgtccccaac aattaattgg taaggaattt
    16321 tgctggtttg agacgcacga atcttgtact gcattttttc attgcggtca tcgacatctg
    16381 cacgaacacc acggtcacga agggtttttg ctacttccca agcatagtca atgtgggctt
    16441 catttgaaat tggaatcacg gttacttggt gaggtgccaa ccaagttggg aaagcaccct
    16501 tgtaagtttc aataaggata gcagtgaaac gttccatagt tgagataaca ccacggtgaa
    16561 tcatgactgg acggtgttct tcgccatctg caccaatgta tttaaggtca aagcgttctg
    16621 gcaacaagaa gtccaactga atggttgata gggtttcttc gttaccaaga gctgttttca
    16681 cctgaatatc aagcttaggc ccataaaagg ctgcttcacc ttctgcttca aagtaatcta
    16741 cacccatctc atcaagtgca gctttaagca tactttgagc attttcccac atctcatcat
    16801 tgtcataata tttatgagta tcgttagggt ctcggtatga caaacgaaaa cgataatcag
    16861 tcaagttgaa gtcagcataa acatcaatga ttaattgaag ggcacgttga aattcttcct
    16921 ggatttgctc tggtgttacg aaaatgtggc catcattcaa ggtcatttca cgtactcgtt
    16981 gaagtcctga tagagcacct gatttttcgt aacggtgcat catgccaagc tcggcaatac
    17041 gaataggcaa ttcacgataa gaacgcacat gatttttata cacttgaatg tggtgtgggc
    17101 agttcattgg acgaagaaca aactcctcac catctcccat atccattaca gggaacatat
    17161 cttcttgata atgatcccaa tgacctgatg tcttgtacaa ttctacagaa gcaagtggtg
    17221 gtgtgtaaac gtgttggtag cctgatgcta attctttatc tgtgatgtag cgctcaagtg
    17281 tacgacgaat agtcgctcca tctggtaacc aaaatggcaa gccttgacca acttcttggc
    17341 taatcatgaa caagtcaagc tctttaccaa gcttacggtg atcacgttct ttggcttctt
    17401 ctagacgagt caagtaagct ttaaggtctt ttttatcaaa ccaagctgtt ccatagatac
    17461 gttgcatcat gttattgtcg ctgttaccac gccagtaagc acccgccaca ttgagcaagt
    17521 ggaagacttg gatacggcct gttgatggca catgagggcc acggcaaaga tccacaaatt
    17581 caccttgacg gtaaaccgtc aagccagcac cagcatgctc attaatcaat tctaccttgt
    17641 aaggatcatc tttgaacaat tccaaagctt cttctttggt cacttcttca cggatacatg
    17701 ggtaattttc tgtcacgatt ttttgcattt cagcttcgat acgtggcaaa tcttcgtttg
    17761 aaatttggcc ttcagcatta tctgtatcat agtaaaagcc ttctgcaatg gcaggaccca
    17821 cacccaaatg aagatttggg aacaagcgtt ttgcagcttg ggcaaataaa tgggctgcag
    17881 agtggcgaag cacctcataa gcatctttgt ggtcaggtgt cacgatttca atactgccat
    17941 cttcttcaat ggcacgagtg gtgtcaatga gttgatcatt gaatttacca gctaaagctt
    18001 ttttagccaa tgatttgctg atggactcag caatgtcaaa cgttgttaca ccagattcaa
    18061 attcacgcac ggcgccatct ggaaaagtaa tcttaatcat ttgctttctc ctttaagtca
    18121 gttaagattt ccactaaaac atagatagta agacaaatta gggacaagag gttagtgaat
    18181 agctcaatac caccacgtag aagaacaata ccttattcac gaatctaccc tccctagtcc
    18241 ttaaaaacaa ggctaatccc ctccaaaaca aaaaaactga ccgcatccca aaggacgcaa
    18301 tcagcgtggt tccaccttaa tttatgcagg acaaaaaaca tgccttgcac ctctagtggc
    18361 gataaggggg ccaccctttt atgtttgcat aaaaaccagg aaggagtatc agattagcta
    18421 tccttgtgct ctttccacca accagcactc gcttaaaaga ttctgtccaa tctaacttgt
    18481 cttcaagatt attatagcaa gttttcaaaa atttacaagc cttaatccag aaaatctttg
    18541 atagcatgga ccagcttgat aggagccttg actactttta ctgaggtgat agctgtgacc
    18601 ttagcagcac gtttaggcaa gtgaatagca ccttgcacta attttagaga actactttta
    18661 ccagaatgat taagataaag tctcagcttt tgagcttctt tgctatttct agcaattaac
    18721 gtatctaaat agaacgtgta aatagatttt ccaaagtgct gtgctgagat ttcataacgt
    18781 ttttttgcta ataaccgctt atccataact ggtgttttta gtatggcatc aataatagca
    18841 tcagttaaat ctgtttcagc gtaataaaga gtgccaaaca ttttatcagt caccacatca
    18901 tctaaataag gattgccatg agcaataata ggagtgccac tagccaaact ttcaatatag
    18961 gtcaagccct gagtctcact agttgatgct gagataaaga aatcacaagc cttatagtac
    19021 agagcaacct tatcatgagg caccatgcct gtaaaggtca cgtgtttgtc aacctctaac
    19081 tgcatcgcca agtgtttcaa atcttgcaaa taggggccat ctcctacaat aataagcttt
    19141 atcttggcat tttcagccaa aatagctggc atctgattga tgatagcttg aatatttttt
    19201 tcataagaaa tccgtgacaa actcaataac atggtttcat caccagcaat gcccaattct
    19261 gcttttaagt tggttacttc ttctgctgtg atgtcatcac gaatatattt ttccaaagga
    19321 atgcctgttg ggataacccg cttagggata gtcacttcgt aaccttctag aagattgagg
    19381 acaatcctgc ttgggcagat aaccccatcc aaatccttca aatagcccct aagaagaggt
    19441 ttgaccatac ttggtcgaat gatttttccg ttggcaatat aactcacgta gtcctcatat
    19501 tgggtatgat aagtatggac aacaggaatt cgcaaagctt tgcctatcat tttccctaat
    19561 aaacctaagc taaactcagt ttgcgtatga ataatatcaa gattatagtg ttttgcaatt
    19621 ttgtatgacg aaatgaggcc gcgataaacc acacgtctat ccgtaaatga cacaaaagga
    19681 acacttggca gtcgaataat ggtcgggtct tcaaagcgtt tgacatctct atcagtagtg
    19741 gtgaaaatat aaacttcgtg accttctttt tctagctctt cttttaacgt acgaatacta
    19801 gtagcgactc ctgaaacttg tggaaaatag gtatctgtga atagacctat acgcatctta
    19861 taactccatt acttttttat agacatctac taaggcatgg ccaaccgttt ctaggcgacg
    19921 actctgggca accttgtaac cagcttcaac tttgttgctg gcaccagaaa agactttttt
    19981 cagagcttct ataaaacctg gtatatcggt tgctaattcc gcactacttt gatcaaccca
    20041 tccgtagtaa actggtatat cacgtaaaac aaggtgctgg cgactggcca aggcttctaa
    20101 gacaacaatg ccttctgttt cttcacgact tggaaagaaa aaggcatctg caccagtcat
    20161 ggcaccttca taaacatctc ctttaatgta tcctgggaaa ataagatttt tcgggtggtt
    20221 accattgacc atttggcgaa cttgagcagg aatgacccat ttgttggtct cgccaaacca
    20281 gataaaacga acatctggca tagcttgggc aactttgaca aagtcatcaa ttcctttcct
    20341 cagaaaaaat aatcctgctc ccataaccac tttttcatcc tctttaatgt caaagtagcg
    20401 acgaaaagct gcttcctttt taggatctgc tccgtactgc tccaaatcaa tcccatttga
    20461 cactgcaaaa ataggtgact tcactccata actctcaatc aaagacttag aatatagggt
    20521 aggggtaatg atagcatctg ccttattgta aaagtgacaa aggtattttt taaaccaagg
    20581 agataataga tttgaaaaaa taaaagaatt tctaaaatct tcttctgtag aatgcccatg
    20641 catgataacc ttcttaccag ctttttgtgc ttttatcatc agcagccaac tttttaaacc
    20701 ataggtattg agatgaacca aatcataagt ttctcttgga ttagtcgtaa aatgttgacc
    20761 aacaagtgac aaggctttag cctgatgctt aatcgctcga ccaattcctg attttcttag
    20821 ataattttct gcttctaaat acaataagac tttcatgagt tctattatag ctcattttat
    20881 agtatttttc actaagacat gcaaaaatca gccctaaggc tgattttagt attgaagaaa
    20941 cagtctattg tgatactttt tgttagatgg tgctcataag tcacagttac ttagttgtcc
    21001 cacgtttttt aataccatga ttcaaaagaa tttctttttc ttccaactct tctttgttca
    21061 tgattttagt caacatccgc atgctaacag cacctaagtc ataaacaggt tgactgatag
    21121 aactcaaatt aggacgagtg tattgaacca ctggtgaatc gttgctggtg atgatttcaa
    21181 agtcctctgg tacgcgttta cctgcttcaa acaagccgtt taaaaggccc gctgccaatt
    21241 catcttcagc cacataagcc gctgttgctc ctgagttaat gacgcgctgc gccaattcaa
    21301 atccttcttt ataagaatag ttcgcttcaa aaacaagacc ttctttgaag tcaagcttat
    21361 tgtgcttcaa cccttctttg taacctgcta agcgcacttt accattgata tcatcaatga
    21421 gtggtcctga cacaaaagcg atacacttat gattttcagc taaaatatca acaacgtttg
    21481 acaccgcagc tctatagtca atgttgacgc ttggtaattg atgatcaaga tctacagttc
    21541 ctgccaaaac aactggagta cgagagcgtg aaaattcggc ccggattttt tctgtcaagt
    21601 gatgccccat aaaaataata ccatccactt gcttggcaaa aagggtattg acaacattaa
    21661 cctccttgtc atcatcttca tcactggagg caagcacaat attatatttg tacatagcgg
    21721 cgatatcgtc aataccctta gctaagatag aaaaataact atttgcaata tttggaatca
    21781 caacgccaac ggttgttgtc tttttgctgg cgagaccacg cgcgacagca ttgggacgat
    21841 agtcaaggcg atcaataact tctaaaactt tcttacgtgt attttcctta acatttttat
    21901 tgccattaac aacacgacta acggttgcca ttgaaacacc agcttcacgg gcaacatcat
    21961 aaattgtaat ggtatcatct gtattcattt tttatcttcc tttctatttg aaaatgacgc
    22021 tttcaaaaag tattttagca tgatttgtaa ccactttcaa gtgttatagg ttaatttttg
    22081 aaaaagtttt caaaaattaa ctcgaagctt gattttttaa gctttttttg aaaaaatagt
    22141 aagtagaaag aaggttagcc tatgacaaaa ttagaccaaa tacgtttgta tcttgaccaa
    22201 aagggagctg aattggcgat tttctcagat cctgttacga ttaactattt aactggattc
    22261 ttctgtgacc cacatgaaag acaactgttc ttgtttgtct accatgattt agctcccgtg
    22321 ctttttgtac ctgcccttga ggtggccaga gctagccagg ccatatcatt tcctgtgttt
    22381 ggttatgttg actctgaaaa tccttgggaa aagatcaagg ccgttttacc aaatacagca
    22441 gccaaaacca tttatgctga atttgaccac cttaacgtca ataagttcca tggcttgcag
    22501 actatctttt cagggcaatt taacaatcta acccattatg tccaaggcat gcgccttgtc
    22561 aaatcagctg atgaaatcaa taatatgatg attgccgggc agttcgctga taaggctgtt
    22621 caagttggtt ttgacaatat ttccttagat gctaccgaaa cagacgtcat cgctcaaatt
    22681 gagtttgaaa tgaaaaaaca aggcattcat aaaatgagct ttgacactat ggtcttaact
    22741 ggaaataatg cagccaatcc ccatggcatt cctggaacaa ataacattga aaacaatgcc
    22801 ctacttcttt ttgacttagg tgttgagacc ttaggctaca ccagtgatat gaccagaact
    22861 gtggctgttg gtcagccaga ccaatttaaa atcgatatct acaatctctg cctagaggca
    22921 caactagcgg ctattgactt tatcaaacca ggtgtaacag ctgctcaagt agatgctgct
    22981 gctcgtcaag tgattgaaaa ggctggatat ggtgagtact tcaaccaccg cttgggacat
    23041 ggtatcggca tggatgtcca cgaatttccc tccattatgg ctggcaatga cttggtcctt
    23101 gaagaaggta tgtgcttctc tgttgaacct ggtatttaca ttccaggaaa ggtcggtgtg
    23161 cgcatcgaag actgtggcca tgtcactaaa aatggctttg aagtctttac ccatactcca
    23221 aaagagttgc tttattttga aggctaagcc cctaccatct ggttaaacaa accctcgcga
    23281 aaggaaggta ttcgtatgga tcaaaccatt catcaccaaa tacagcaagc actacacttt
    23341 agaacagccg ttcgtgttta taaggaagaa aagatttctg atgaggattt agcccttatc
    23401 cttgatgctg cttggttaag cccttcttct gttggcttag aaggctggcg ctttgtcgtt
    23461 ttagacaaca agcctattaa agaagaaatc aagccctttg cctggggggc ccagtatcaa
    23521 ctagagacag ctagtcactt tattctttta atagctgaaa aacatgcaag atacgatagc
    23581 cctgctatca aaaatagcct tttacgacgt ggtatcaaag aagatgatgg tctcaacagc
    23641 cgcctaaaac tctatgaatc tttccaaaaa gaggacatgg atatggcaga taatcctcgg
    23701 gcactctttg attggacagc taaacaaacc tatatcgctc ttggtaatat gatgatgaca
    23761 gctgctcttt tgggcattga tacttgccct attgaaggct ttcattatga taaggtcaat
    23821 catatcctag ctaagcataa tgtgattgat ttagaaaaag aaggcattgc tagcatgtta
    23881 tccctaggct atcgcctgcg agatcccaaa catgctcaag ttcgtaagcc taaagaagaa
    23941 gtgatttcag tcgttaaata aggagattaa aatgaaagca ttacatacct gtatccgcgt
    24001 caaagacctt gaccagtcgg tagcttttta cacaagcgcc ttccctttta aggaaaacta
    24061 tcgtaaagat tttccagata gtcaatttac tcttgtttat ctggctttag aaggagaaag
    24121 ttatgaatta gaattaacct acaattatgg tcatggcgac tacgacttag gaaatggcta
    24181 tggtcatatt gcccttggct ctgaacattt tgaagcagac cataaaaaac atcgacaagc
    24241 aggttttcca gttaccgata tcaaagaact ggctgacaaa tctgcccgct attatttcat
    24301 tcaggatccg gatggctaca aaattgaagt cattgattta aacaactaat actattaaca
    24361 acagaagctt taaagcttct gttgttttat tttttaacct gacgattggg acaatctcat
    24421 tattaacaga gttttgaaat atctcagctt ttgtgttaca attgccctaa aattccattt
    24481 gaaagaaaag tctatgacac tactatctat cattgtcccc tgctttaatg aagaagcaaa
    24541 cattctccct tattttgaag aaatgcatca actagaaacg tccatgacca accaacttgc
    24601 ttttgaatac atttttattg atgatggttc taaggataac accttgggta ttttgcgtga
    24661 gctagctgct cgctttccaa atgtgcatta tctgtctttt tcacgccatt ttggcaagga
    24721 agctggactc ttagctggac taaaagaagc caaaggcaat tacattactg tgatggatgt
    24781 ggatctgcaa gatccacccg aacttttgcc aattatgtac gctaagctaa aagaaggtta
    24841 tgacatcgtt ggcaccaggc gccaaaatag acaaggagaa ccactaattc gttcaatgtg
    24901 ttcgaatcta ttttatggac tgatcaaaca cttatcagat actgaaatgg tcaatggagt
    24961 tcgggattat cggttaatga ccagacaagt cgttgatagc attcttgagt tgggagaggt
    25021 taatcgtttt tcaaaaggga tcttttcgtg ggttggttat cgtatcacct atcttagttt
    25081 tgaaaaccaa aaacgcaaat atggaaaaag tcgttggcat ttttgggagt tgctccgata
    25141 ttctttagat ggctttatca acttttcaga aatgccgtta accattgcta cctggacagg
    25201 gactttcagc tttttgattt ctattttcgc catcttattt atcattatca gaaagatact
    25261 ctttgatgat cctgtctctg gttgggccag cactgtctct attattttat tcatgggagg
    25321 cattcagctc ttttgcatgg gtattattgg aaaatatatt tcaaaaatat tccttgaaac
    25381 taaaaaaagg cctctctata ttatcaaaga aaaacattaa attaaaacat ttttctcatc
    25441 aatcgtttcc tactccttct gtgcgcgaag ctttcttttt aagcccgtta taccaaatga
    25501 taatgacctt tccaaaatag tatcaccttc cttaacactt taagtagaaa aggaactatt
    25561 aggttgagcc tttttgcaaa tcctagcgac taatgttata atcgtcatac tattgaaaaa
    25621 ggagttcttt atggagtggt ttaaattaat cggtattgtg attatcgtat tagggtttat
    25681 tttaaaattt gatgctatcg ctaccgtagt tgttgcagga cttgttaccg cgctggtttc
    25741 aggaatttcg tttatcgatt ttctagatat tttaggaaaa gaatttacca atcaacgttt
    25801 gctaaccatt ttcttcatca ctttaccgct tatcggcttg tcagaaactt atgggctgaa
    25861 acaccgagct actcagttga ttcaacatgt tcaatccctt accgtcggcc gtttattgac
    25921 tctctacctt attattcgag aattagcagg tctcttttcg attcgactag ggggacatcc
    25981 acagttcgtt cgccccttga ttcaacctat gggagaagct gctgctaaag ccaacattgg
    26041 agaagagttg accgatacag aaaaagatga catcaaagct atggcagctg ccaatgaaaa
    26101 ctttggcaat ttctttgccc aaaatacctt tgttggcgca ggaggtgtcc tacttatcgc
    26161 tggaacttta gagcagcttg gctatgatgg taaccaagct aaaattgcat tttcttctat
    26221 tttaattgct attatctcta ttattatagt tgctatttac aattacctct ttgagaaaaa
    26281 aatggaacgt caacatcaga aaggagataa ctaatggcta acattgcaaa ccttgtttta
    26341 gaaacgatat atatccttat cggcttgcaa ctgtttcaca cagcctactg cacctttaaa
    26401 gataaaacca accctgtcta ttttgggaca gctctgttct ggggattgct gggtgttacc
    26461 ttcgttggcg gtgccttttt gcctaataaa gttatcggtt ttatcgtgat tgtcctagct
    26521 cttttaacct tgtttaagca agttcgtatt ggaacattac cagcctttaa tgaacaaaaa
    26581 gctgaagaaa gtgctcaccg cattggtaac tggattttct taccagttat gttaatggct
    26641 atgatttctc tacttcttgc cttgatcctt cctgatttca gtaaaagtgc cattgggatt
    26701 gctggtatct tagccactat tgctatttta ataatcacta agcaaaaacc atctgctctt
    26761 ttagctgaaa ataatcggat gaaccaacaa gtgtccacaa gcggtatttt gccacagctc
    26821 ttaggagctt taggagctat ttttgcagct gctggtgttg gtgatgtgat tgcttctctc
    26881 attcgggaga ttgtacctgc tgatagccgc ttctttggcg ttctcgctta tgtgcttggc
    26941 atggttattt ttactatgat tatgggaaac gcttttgctg cctttaccgt tattacaacc
    27001 ggtgtcggtg ttccttttgt ttttgcttta ggagctgacc ctattattgc cggtgcttta
    27061 gctatgactg ctggtttttg tggtacctta ttaacaccaa tggcagcaaa ctttaatgcc
    27121 ttgcctgttg ctttgatgga gatcaaagat cgaaatgcag ttatcaaaaa gcaagctcct
    27181 attgcccttg ttttaattat tagtcacatt gccttaatgt atttacttgc ttattattaa
    27241 ctttttttgc taagttagta gcgtcagtta ttcattgaaa ggacattatt atgaaaattc
    27301 ttgtaacagg ctttgatccc tttggcggcg aagctattaa tcctgccctt gaagctatca
    27361 agaaattgcc agcaaccatt catggagcag aaatcaaatg tattgaagtt ccaacggttt
    27421 ttcaaaaatc tgccgatgtg ctccagcagc atatcgaaag ctttcaacct gatgcagtcc
    27481 tttgtattgg gcaagctggt ggccggactg gactaacgcc agaacgcgtt gccattaatc
    27541 aagacgatgc tcgcattcct gataacgaag ggaatcagcc tattgataca cctattcgtg
    27601 cagatggtaa agcagcttat ttttcaacct tgccaatcaa agcgatggtt gctgccattc
    27661 atcaggctgg gcttcctgct tctgtttcta atacagctgg tacctttgtt tgcaatcatt
    27721 tgatgtatca agccctttac ttagtggata aatattgtcc aaatgccaaa gctgggttta
    27781 tgcatattcc ctttatgatg gaacaggttg ttgataaacc taatacagct gccatgaacc
    27841 tcgatgatat tacaagagga attgaggctg ctatttttgc cattgtcgat ttcaaagatc
    27901 gttccgattt aaaacgtgta gggggcgcta ctcactgact gtgacgctac taaacctatt
    27961 ttaaaaaaaa acagagatat gaactaactc tgtttttttt gtgctaaaaa tgaaagacct
    28021 agggaaactt ttcattggtc tttctcaatt gtcatcttaa tctaatacta cttctaacat
    28081 cagcgggtat agtttgccag taattaagaa acgttgttga tctaaatgag caatcccatt
    28141 caaaacatta aggtcagggt aatgggactt atcaagattt aaggctttta acaaaggact
    28201 aatatcatag gtggctacca cctttccaga atcaggttgg agtttgacaa tagtattggt
    28261 ttgccaaata ttggcataga gataaccatc tacatactct aattcgttaa gcattgagat
    28321 ggggacactt tctatagcaa ctagtacggt atccaataaa gcaaaatctt tggggtctcg
    28381 cttttgcaaa aaagcatttc cactagtcat ccaaagacac tggttttcct tatcataggc
    28441 taatccccag ccatctcctt caaatggata ggcccctaaa caattgcagg tagccttatc
    28501 aaacttgtag gctacaccct ctttataggt tagtaaccaa aaataatcct caacaactgt
    28561 tagcccttct gcaaaaactg tatctggaaa agctattttt tctgaaaaga tctcttgagt
    28621 aaggtcatac acccctactt ttgagaaacc ataacgaccg gcactaagta atatatgatt
    28681 gttgttgagt tgttctaatc cctgcgtgta taagttgcta tcataagaat aagttcgtaa
    28741 caaacgaact tgtcctttag ttatcataat actcattcac cttaccttgc attgtagtgt
    28801 ttcatttgtt ttttaatatc tctttcctga tcacggcgtt taatggtttc gcgtttgtca
    28861 taatcgtgtt tccctttagc tagaccaatc agaactttag caaaaccatc cttgaggtaa
    28921 actttgagag gaactaaggt cattccagtt cctttaagtt catttgctag atgcgtaatc
    28981 tcacgttttt tgagcaacag tttgcgggtc cgttcaggat cagcgttcca aatattacct
    29041 tgttcaaaag gtgcaatatg cacgttgacc aaccacgctt ccccattctt aatttgggca
    29101 aagccatctt tcagttgaat acgagctgca cgaacacttt taatctcagt tcccgttaag
    29161 acaatccctg cttcaacggt ttcaacaata tgataatcat gtctagcctt tttattttgc
    29221 gccagtatat gaccttcacc ttttgccata gttaactcct tttacgactc ttcttttttg
    29281 cttgttcttt gtaaaatggt tttttagacc cttttttagt tttaccctta gtttttgcct
    29341 tggctacttc tttaggttct tttttctttg tccctttaga tgattttgag gatttacggc
    29401 gatctcgtcg actagcttta tccgacatct tgattttttc aaccacatca aagtcgctag
    29461 gtaaatactc aaagtcaatg tcaccagttt ccttgtcagc cttaaccaat ttcacacgaa
    29521 taggttgacc gaccttaaag accttacctg atttttcacc ttgaaggctt agcgttcttt
    29581 cattaaagtg atagtattcc ggtaagctag tgatatgaac caaaccttca atcgtatttg
    29641 gcaattctac aaaaaaacca aatttaacga cactggccac gataccgtca aattcttcac
    29701 ccacatactc tgccatatac tcagcttttt tcatggcttc aaccacgcgt tcagcatcaa
    29761 tagcacgacg ctctaactgt gaagaagatg ttgctaattc tggaatgatc tgagtaaaat
    29821 ggtcgcgctt ttcttgacta ggttgactgt actcacgaac catgcggtga accaacaagt
    29881 cagggtaacg acgaatcgga ctggtaaagt gagtgtaata ttctgcggcc aaaccgtaat
    29941 gcccatgatt atgttcagaa tatcttgcct gttgcataga gcgtaagagc atcatgttaa
    30001 gcacttctgc tcctggttga ccttcgactt ttgccataaa ggcttgcaag gcttcctgag
    30061 aaatcttgtt ggctgttcct tgaatgtgaa taccaaaggt gctagcgtaa tcaataaatt
    30121 gttgaagttt ttcggccttt ggttcttcgt gaatacggta gataaacggt aacttagctt
    30181 ttgcaaaatg ttctgccaca cactcattgg ctgctagcat aaaggactca atcatccgct
    30241 ctgcaattcc cctttgacga agcaccacat caaccggcat tcctttgtca ttaacaataa
    30301 ctttagcttc ttgcgtatca aaattcaagg cgcctcgttt tgaccgcata gcttccaaaa
    30361 tcctatgcaa agccaccatg agggtcacat catcagcaat gctagcgaat tcttggagcg
    30421 cttcttcatc tcctgcaatc atgtcattga ccgtactata cgtcattcgg taagttgtct
    30481 taatcactga ttgacagatt tgataattga ccacatgccc ttgagaatta atttccatca
    30541 aggctgactg ggtcaaacga tcaacgttag ggttcaaaga gcagatgcca tttgacaaac
    30601 gctctggtaa catcggaacc acacgatcgg tgacatagac agaagtgcca cgggcgatag
    30661 cttccttatc aagggcagat ccttctgtca cataatatga gacatccgca atatgtaccc
    30721 caagttcata gttaccgtta tccaatagct taatatggat agcatcatct aagtctttgg
    30781 cgtccgcacc atcaatagta atggtggttt cttgacgcaa atccacacgg cctattaaat
    30841 ctttagcagt tggtgcttct gaaatagcat tggcctcggc taaaacttct gctgggaact
    30901 ctgacacgat atccatcgat tcaaggactt ctaggacatc aattccaacg tctccttgat
    30961 ggcctacgat atcacgcaca ctggctacaa aataatcgtg cccgcgtgtc gggtatttat
    31021 caatatcaac cttgatgatt tcagtgcctt taagcacaac aggttctttt ttgatataga
    31081 ttttttgttg aatcttttgg tttttggacc tgatataacc agcatatttt ggtttgtcat
    31141 catctaaaat aaaggttcca acagctgttt ttaaagaacg gtcaacaata gcaacgacct
    31201 tagcttcagc cgctgtgcct ttgagacggt ctgctggctt tttaaccact acttcgacag
    31261 tatcaccatc aatagcatac ccaacatcat tacgaccgat aaacatatcg tcttcattct
    31321 catccacatg taagaaacca aagcctgctt tattggcacg aaaaacaccc tgaacagtag
    31381 gttctttttt cttttcacgc tcttttctaa gagccagact gccatcatct gaaaatcgta
    31441 acaggctctg actttccatt ttggaaatgg ttttaataag gctgggaaaa tgcttagctc
    31501 cagccatctc caaggccgca gccaagtcgt tcacattgga cttgccatgc tccttgaggt
    31561 aagtcataat tctttctttc atcataccta atttctattt ctgttttgtt tgttggagga
    31621 tatcaatccg tttcgctgat aaaaaaatga gctagactaa ctctgtcaag ctcactcctt
    31681 atttacttga taaaatggca agcacaagtg caatcgctag ccaaaaaaat actagaactg
    31741 ctgtgaatcg ttgcatgaat gcttcaaagc cacgagcttt tgtacgttca aacaaggctt
    31801 ctgaaccgct gctatcaaaa acattgctac ttgggttttt ttgaggttgc ataaaaatag
    31861 caatcacaag caataccgac agtactagca atatcgtaag tagtaagttg tacatgttat
    31921 ttcctccact attgtcatga ccattctaac acaattctta tcaagtttca acatgcaggg
    31981 tcacttttct ctccttgggg cagtatttgg gaacttttat tttttccgga tgactgcttt
    32041 tatttttact ggttagataa ttgttactgc cacactcact acattctaaa ttaattttta
    32101 ctctcacaca atatccttaa ctttaatata ttttcgaaat ataatcaaac tccatattaa
    32161 attaacaaac acaatcaaac tagtcacata aaaaacagaa cggtagccta acactacagc
    32221 cacatttgat ccgataaaag ggccaatgac ttgaccaagg ttactaaaca tttgattata
    32281 ggcaaatact ctagaaatac cttcttttgg tgttaactta gttagtaaag agttaatact
    32341 tggcatcaaa gcgcccacac caaacccata agcaaagcgt agtactccta attgaaaact
    32401 ggtctgcgct aaggcactgc taaaatacat gataaagcta taacacaaag cggctaacaa
    32461 taaccgatga ttgccaaatc gatctcctaa ttttcctaag taagaactgc taaataagct
    32521 agaaaacccc atggccgaaa ctaccaggcc tgaagtaaac attaagttgt gagtttgacc
    32581 aagatgacga atatacaatg ataaaatggg ggccactgat tgagctgaaa tttgaataat
    32641 catactagtc acaaataaac caagcataat ctggggactt tttacctgtt ttaaaatgac
    32701 ttttgtaggt atcatctcaa agcgcctaac cggcttaaac tcttctttaa cataaacagc
    32761 tgtcattaaa gaacataaaa ataatatcac accaactaat aagaaaactt gtcgaattcc
    32821 taatagctct gccaaaattc cccctagtaa aggaccaatt aaagcgcctg ctgtcactcc
    32881 tgttgctaat gtgcctaaag cataacctga ctcctctttt ggggcttggc tggcaatcaa
    32941 ggcagtggca tttggcacat agcccgcaaa gacacctgtt aataatctca aaatgagtaa
    33001 ccaaaacaca ttaggaataa tagctaaacc acccattgta aatgtcatga caaaacttgc
    33061 tcgcagcatc ataggttttc ggccataacg atcagccaac ttcccccaaa caggagcaaa
    33121 taaagctgaa gcaagtgccg tcacagcaac tgccagacca gcatagtatt ctactaattc
    33181 tttcggagta cctaaatttt ccacatatag agccataaaa ggcataacaa gtgaaaagct
    33241 tgccccagta aagaagttac caagccaagc cacttttaga ttttgtcgcc agttcactgt
    33301 cgttaccgct ttatcactaa tagatcatca tcttctttcc attgggcctt tgattattat
    33361 aacacatttc tgccaaaaac agtgtcccat aatagtgcta agtctcatct gatagccttc
    33421 atcgtttacg taaactaccc agtaaacctc tgaccagttc tcgcccaatt gttctaaccg
    33481 tcgtactaat aaacgcatct gttgcttttt cgacgactgt tttgcgggga cgcccaacag
    33541 aacggcgact agccttttca gcagcagctt gttccttgat ggcttcttta gcttcttttt
    33601 cgcgttgtgc tgtcgctatc gcttcttggg ccagtcggtt gtcttctaaa accttagcag
    33661 ctaatttttc ataagcagat tcacggtcaa tgaactgact atatttactg gcaaaaggtg
    33721 aggactgcac aagctgctga ctttctatct ctgacaaaac agcaaagcta ctcttaggcg
    33781 gcatgatata ggcacgttca acgatggatg gttgtccctt atcattcaaa acagaaatca
    33841 aggcctcacc gacttctagt tctgtaatca cccttgccac atctaagtca ggattttgtc
    33901 ggaaagtatc cgcagcgaca cgaaccgcct tttgttcttt cggtgtataa gcgcgcaagg
    33961 catgctgaat acgatttcca agctgagcca aaaccgtttc tggcaaatca agtgggtttt
    34021 gagtcacaaa gaaaatccca actccctttg aacgaataag tcgcacaatc tgttcaactt
    34081 tttccaagaa aactttaggg gcatctttga agagcaagtg agcttcatca aaaaagaaaa
    34141 ccatcttagg tttgtccaaa tccccaactt ctggcaataa ttcgtacaac tcagacaaga
    34201 gccaaagtaa gaaggttgtg taaagggtag gagattgaaa aagcttagtc gctgacaaaa
    34261 tgttaatggc tccataaccc gaagcaacat ctaattgcat caaatcagcc acatctaaag
    34321 caggctctcc aaaaaattgg tgggcccctt cttgttctaa tgtcaagaga cttctttgga
    34381 tagccccgat agattgcttg gcgatattac cgtaatggct ggagtagtct gaggcatagt
    34441 caccaacttc ttttaagata gcctgcaagt ctttcaaatc aatcaaaagc caacctttct
    34501 cgtcggcgat tttaaagacg atgtttaaga cacctgtctg ggtatcatta agattcaata
    34561 aacgcgacaa catcataggt cccagctcag aaatcgttgt ccgtaagggt tgaccgtttt
    34621 gaccaaaaac atcccacatt cttacaggaa aggcctgagg ctggtaatca cttaccccga
    34681 ttgtggctaa acgcgcagcc aatttatcag tcacctctcc tgctttagta agattagaca
    34741 ggtctccttt gatatctgcc aaaaagactg gcacaccagc taaacttaat tgctctgcta
    34801 gcacttttaa ggtcacagtt ttacctgttc cagtcgctcc aacaatcaaa ccgtgacgat
    34861 ttagcatccc taattgtaag gctatcggtt gactgccttt tgcaattgtc attgtagtca
    34921 taggcttcct cttttttgat gatcatactt gtcgatatgt gtttacccat aagttaaagt
    34981 gtttagaagg gtctcactct taatactatt ataacatata acccttgatg cgctaattta
    35041 aaagggacca gctagtttta gacagaaata gcttgatttt gacagctatg atacgaatct
    35101 ctcagcttag ctacctcgga ttggctaatg acaacaacgc agattgtact tgctttatta
    35161 aggctgcaat atccccacta ttatcaatca ctagactggc atagggcttt ttttcctcta
    35221 ttggtaactg actggctatt cgctgccttg cttttccttt gtctaaacga tttctagcca
    35281 ttaagcgctg caattgtgtc tgagcatcta cataaaccag ccaaatcgca tcaaaccagt
    35341 cttggtagcc caattctatt aaaaggggaa tatccatgaa aaaaatggct tggctctgtg
    35401 ctaagtggtc acgcttagcc gccaattctt ccttaatgac ttgattttga atggctgagg
    35461 atgttgccat attatctggg tttgaaaaaa gcatttctga cagctttgtg cgatctaact
    35521 caccatctgc ttttaaaatc tgattcccaa aagcttctct aagagcctcg taaaggcgac
    35581 cgcctttttc ttgcaagtca tggaccactt gatccgcatc aatcacctga taaccagctt
    35641 ttctaatgac cttaaccaca gtcgattttc ctgatgcaat gcctcctgtg atgccaataa
    35701 tcatggtctt tttttctggc attttggaca aatgtgcgtc ccccttcctc caacttttaa
    35761 tttgacaata gcctgtccac aacgaggaca cggtttccca gtttgaccat aaacctgcaa
    35821 atagtcctgc atggtgccat cagctcccaa agcattacgg taagtacgga cggtcgaacc
    35881 gcccttttca attcctaaag ctaggattcg tatggtttca tcatgcagcc gttttatctc
    35941 cgccttattc aacctagaag acgcagtttc tggatgaacc ttagcagccc aaagtacctc
    36001 gtccacataa atattcccta aaccagcaac caaggtctgg tctaacagat gtggttttat
    36061 gggtttttgg gaggatagca gagcagcctc aaaggttttt aacttaaagg tctctttctt
    36121 tggttcaggg cctagttttc gtttggcaaa aaacgctgat aattgagatt ttgctatcaa
    36181 atcaaaggtt ccaaatttac gcacatcttg gtaaaccaag gtcgaaccat ttttcaattc
    36241 aaaaaagaca tgaaagtgtt tgttatcaga gacctcatct ggaaaaagca aatatttgcc
    36301 ttccatccgc aaatgtgata ccaacactaa ttgccccaaa tcaattaata aatattttcc
    36361 ccgacggcca actgactgaa tgatttgacc aggtagggtc agggcaaacg tctctaagtc
    36421 ggttttaacc atttttggca ctttaagcgt aacagccaca atttcttggc caagcactaa
    36481 agtctcaagc cctcgtcgga ccgtttcaac ttctggtaat tctggcataa tccattattt
    36541 aaaggacagc tagacccttt gctgctacaa agaataaact cagcataaaa aagtcactca
    36601 atagactcag gtctaggcta ctgactgcgt ttcaaaaaac acagctgtcc ttctcctttc
    36661 ttatttctta ttttacgaac acatctgata gaaagcaact cataaatctg cctcagacca
    36721 gtcctcatcc cccttacctc ccagcactat ttggcggtaa tgttccttat aactataata
    36781 caatgagtcc tctccaagat acttaaaaat ctgcaaggcc tgccgcatgt cctcttctcc
    36841 agacatttct tcctgcttta atttataata cccatgcaca tataagaaaa cagtcttttc
    36901 ataaaaattg agctcgtctc gcagcaaaag atcaattttg ttaatcaaat agcgactatg
    36961 ttcaaagcaa gaatggtcaa tactgataat gagacaatta atggataact gagtcactaa
    37021 cgttttattg gttttatttt gttccgaata agcaaaagat gctaccattt ccttagtcaa
    37081 taaaaatagg gtattgtaat tcatgaagcg cgagcaattc ccaagaagaa tgatttcata
    37141 atatccccac tgttccactt taaataaata atctgtgagg cgagtcaatt cttcttgact
    37201 aggtgcaatt gaggagtcaa tagaaaaaag aatagcttta atcatcgttc gttcataatc
    37261 tttatgggca taatccttca acagtttggt caatttaacc acgtttttct cagcataaca
    37321 ttttctcgcc tgacttaaga gcgtgaaaaa atgcgtatgc gtcttggaat gagccgaaac
    37381 aaattcgtca atcgtaatat tcagtttatc caaaagatta agcaagcgac tgcaggtgat
    37441 ttctgattcc cctcgttcaa atcttgaaat ttgtgacttg gacaggtatt catctgctaa
    37501 aaaagaaatg ctaacctgct tacccttacg taatcgcctt aaggtttttc cgagttcttt
    37561 ttccattttt cccactttca caacaaaaaa ttaaaatctg ctaaatccat tatataatac
    37621 aagtacaaaa tagaaaatca gaaaggagac agtcatgaaa aaagttaata aagctttgct
    37681 ttttacattg atcatggata tcctgattat cgttggtgga taacctttcg cttaaaaaca
    37741 atccactttt gggaaaccct tatatttagt ttgtaacagg aaaactaata aatattaaaa
    37801 agagtgttag cgacctagcg gcagctttac tcttaagtgc gtttgctgcc attgacagca
    37861 aggtcaaagc tgatgaaaca gcaggagcat accgttatga tgtgtctgaa caaaacactt
    37921 actatcaaac tatcagctcc attaaccagc aacgacctgg tgccactctc gacgaatgag
    37981 gtgattatta tggaaccctt acttcattta cttcccaaag tcgtaccagt acttatacac
    38041 ttggtagaca aagccaacgt atcatggtta acagtgatat tacagttacc tatactctta
    38101 aagacaattt ggtagccctt cataaggaat acaaaacctt tgtcaaaaaa atattacaga
    38161 taaaccgatc accagtgact acgacaaggc taaggttatt tataaccatt tactcaacga
    38221 atacacttac gccacaaaat aacttagcac caatcacaaa accgtaagca gcatcaacaa
    38281 tcatactcct aaagctcttt atcgtggcaa gtgtggtgtt tgtcaagctt atgccgtcat
    38341 gtttaaagat atggcagaag ctgcaggctt atcagtttgg tatgtgataa aaaaggattg
    38401 aatgagcacc atgcttgaaa catcgttacc attcatggtg ttaattccta cgttgatgct
    38461 acctggaatg attcagcata caccacaagg tatttccttg ctggaaaaga cgtgaggaat
    38521 actgagtacc gtttagatag ccagtacaac cacttggcta atgctatttt aaataccagc
    38581 taccaaaaag gctaaactaa caacaactac atttttcaac tagaaaggcc taaacaatga
    38641 ccaaaaaaca gttttatctt atcttagcta ttagcatact gtgttttatt cttgccgtca
    38701 gccctaaacc accaattcct aaacacacta ttgaaaggaa aaggactgcg atgaccatag
    38761 gccactcaaa acaaaaccct cacaaaaaag aagcccttaa acacaaaaaa aataaaaata
    38821 aggctctatt tcttccaagt ggggacagcg ctatcaaatc tgttattagc atgacagtta
    38881 gactcctgtt agatgaccaa tcttagctct cctaaaatca gtggacacta ccatttcggt
    38941 agtgttcttt tttaagctaa tctcatcacc acgctttctt caagctaaaa aactgatcat
    39001 gaaagagcaa ccccatcacc ctaacagccc actttgcccg cactttctta aaaagttagg
    39061 agaaaacgat ataccaatta ttttctgatc ccagctccct atcattaaca agatgtgtag
    39121 cacggaccta catacaggta agctagagtc attctcgcta tttcggacaa aaagaggccg
    39181 gtagttccct gacctcttct ttatttatct tgtaacactc ctcttcttag cgagacttac
    39241 tagcacataa ttcttaagca ctcttatcat ttagactagg aagaacacca tctgaatgaa
    39301 gcaaatgatg cgtcagatct gccagagtat catctccata agtaatccct gtttggtgct
    39361 gtttctgatg aaaatcagat gactccttaa ctttagcagt cacctgctgg tcacttggat
    39421 gaaaattaat ttctctcttg gcttcagccg taactggctc gaggaacaac ttattgacat
    39481 tacggtcttc ctccaaatga ttaaggatag cagcatcatc ttctaacgaa agaaccttct
    39541 tggataacaa aaaggggtta tttagccttg gctcagtaac gacttccttg gctactcgtg
    39601 atagtttatt attgtcttcc tcaggtaatc gatgcaattc ttccggctgt gaggcgctca
    39661 cagctacttc agaagaaacc tccaagccct ttcctgtttg cctgtctaaa gcaaccggca
    39721 aattattaac taacttttta acctgtcctc agcgctcatt tcaacactag gaagagctgt
    39781 cgctggttct agccagctac caacttctgc tggtcttacc ttaacatcgc tggcaggctt
    39841 ctccttctca tcttgattag gtctaaaagg ctcaaaccgc cctgttgatt tttcatctat
    39901 gacctttata ttgtctttta ctacatgaga cagcggttcg acatttacca tagcttcatg
    39961 ctcgttaagg ctctggtctc gtttgaattt accaggaata ccaggagtcg gtgtcccgac
    40021 agattgatcg gcttcagtag gctcttttac ggagcctttt ttccataaaa ctgctggagg
    40081 aataatatcc gtagagccat ccccataagt aatcgtagcc tgcctcccct ttggattaat
    40141 agatacttta atattgtctg ggaaagcccc actacctcct gtggttaaaa gggcacccac
    40201 atttttaatg agagttgtca ttcgttcaat accagcaagg ccaatatggt tcaagtcatc
    40261 tactggtaac tgatcaacag atttcatggt gtatttccaa gcttgcggtt gaacaagaaa
    40321 aacagttcct ttatacattg tgttatgcat atcatcaatg actttgaaat accttgtata
    40381 tttggtttgt acattagggt tagcaacggg aacagtgctt tcaggaactc ctgacatcgt
    40441 aaaaatccct ctagcagaag tttgaaagcc ctcataaaca tgacccatac caggaacagt
    40501 ctgagcggtc aaagacttac cagaaccatc caaagcaatg cgaatatctt tcatcagata
    40561 catctgattg gtataggtaa acctaaccgt gttagcctca cctcgataca aaaccacttg
    40621 ggagggctga tccgaagaaa actgagaggt tgtttcttcc ttatagccaa ctccaaaacg
    40681 tctatcagac gaatggactg aatctgccgc aactgtacta ctcaaactga ctagtaaagt
    40741 agccgcacaa ccaactaata aactgctcgt tttaacttta acatctctta acatcatcat
    40801 gttcctttca ttatttttta tttaggaatt cgtcatacta tattttctca tattagtcta
    40861 acaaaaaact cgtaattcta tataaatcat ataaaatgac gagctttggc aaagatgagt
    40921 atagcaggat ggaaaacaga ttgtttctga aacttcaa
//
LOCUS       DAUNLR010000013        37340 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUNLR010000013 DAUNLR010000000
VERSION     DAUNLR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37340
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.013"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            122..517
                     /locus_tag="VLL59_000635"
     CDS             122..517
                     /locus_tag="VLL59_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HER6508781.1"
                     /translation="MIDFFIPMKKIPTTTHQQKKVRVVNGKPQFYEPDSLKEARAMFM
                     SKFAPHAPEKKMTGPLRLTVKWLFPRIKKSIDGQYKDTKPDTDNLNKLPKDCMTELGF
                     WNDDAQVASEIIEKFWADTVGIYIKVEEL"
     gene            514..738
                     /locus_tag="VLL59_000636"
     CDS             514..738
                     /locus_tag="VLL59_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508782.1"
                     /translation="MKIDYINFFERVVPDWMRESNVKMQEVGFNTEAYWIWANQSIVT
                     ICETYGNDSLINGQFHLIWEWLESKTKESS"
     gene            741..926
                     /locus_tag="VLL59_000637"
     CDS             741..926
                     /locus_tag="VLL59_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508783.1"
                     /translation="MVKHVVRVYNKGITATYAIYDKNLFQEHEFVTKIEAMQFIRELE
                     LANDKRANEYFLREVEG"
     gene            971..1207
                     /locus_tag="VLL59_000638"
     CDS             971..1207
                     /locus_tag="VLL59_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HER6508784.1"
                     /translation="MKEFGDAIKKPSHYQGRHGMEAIDVVKNFGACPEYEEGFYWGNA
                     VKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            1204..1473
                     /locus_tag="VLL59_000639"
     CDS             1204..1473
                     /locus_tag="VLL59_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508785.1"
                     /translation="MKKPNRYPYSKSKFNGCIYQLHSASFKDEQYVKDLKSCGIHYQI
                     TKFGHFPDVFIKIDNLEQLQALIDKTGHDLILSKNEIWIYDDYME"
     gene            1483..1767
                     /locus_tag="VLL59_000640"
     CDS             1483..1767
                     /locus_tag="VLL59_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508786.1"
                     /translation="MTTDELLQNLRDNLNKIMNVLKSDWKALLFLTIAILGMMVTVSY
                     FSYRDAQQYYEPQIYGLRAQLSRTQKQLKRASEDRARQTKRIAEMTGNGG"
     gene            1771..1953
                     /locus_tag="VLL59_000641"
     CDS             1771..1953
                     /locus_tag="VLL59_000641"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508787.1"
                     /translation="MPELINTADLQTPIEALEDNLDFFKGFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            1943..2101
                     /locus_tag="VLL59_000642"
     CDS             1943..2101
                     /locus_tag="VLL59_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508788.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            2120..2593
                     /locus_tag="VLL59_000643"
     CDS             2120..2593
                     /locus_tag="VLL59_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HER6508789.1"
                     /translation="MNIEEAKEKIKEISYGTGIFLTNYEVNSKKVLEILDQLDKPKPE
                     VPQFVADWIEECEEEGLTLKGLFSNSDMPAKIFDWIFGSDENCRLMAEAWINGYTVEK
                     EKLYTVDLPNGQPLVRGINTLYFSQNLATENVKLTESEIRKDFEWAWQFAEEVTG"
     gene            2590..3003
                     /locus_tag="VLL59_000644"
     CDS             2590..3003
                     /locus_tag="VLL59_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HER6508790.1"
                     /translation="MSRLSNAQLKAFDEWLFDYREIGRKIALRKLELQTPVSTDINAG
                     GGKANLVAKETEDIVVKWSEDGKIKSYENFRESVDRVKALLDKELTEIFELRWGVGSN
                     NTWEEIAYKIHTSRAGTYRKRDRILTLFAQEIGKL"
     gene            3129..3824
                     /locus_tag="VLL59_000645"
     CDS             3129..3824
                     /locus_tag="VLL59_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HER6508791.1"
                     /translation="MGRARDPNRDKAFELYKQNNGDITNRKLGEMLGVPEKTISVWKL
                     RDKWKECSTTKNRSTAKRPRGAPKGNKNGKGGTLGNTNALKHGLFAKYLPKGVYEITQ
                     DIESKPPIDILWDNITLTYANLLHAQKILHVTDQQDHANFITSEGKAGIGYERHTSWD
                     RQTNALTAIARVQAELRNMIKTYDELTRSELVTDEQRTRIELLKVKLDAEKGSKPDTS
                     LMEALLDAVEGGD"
     gene            3863..5113
                     /locus_tag="VLL59_000646"
     CDS             3863..5113
                     /locus_tag="VLL59_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HER6508792.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLIMTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTVERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTFIGEPVEMYFCADGGQSDATSMSCNIITRVRDNGKISFRLNRVAHYYHSGA
                     DTGQVKAMSTYAIELKVFMDWCVKKYQMRYTEVFVDPACKSLREELHKLGVFTLGAPN
                     NSKDVSSKAKGIEVGIERGQNIISDGAFYLVNHSEEEYDHYHFLKEIGLYSRDDNGKP
                     IDKDNHAMDEFRYSVNVFVHRYYN"
     gene            5127..6629
                     /locus_tag="VLL59_000647"
     CDS             5127..6629
                     /locus_tag="VLL59_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HER6508793.1"
                     /translation="MGVIQKIKNLVTRSKYVMTTQSLTNITDHPKIAISQLEYDRITT
                     NLKYYKSDWDSVLYLNTDGETKKRNLNHLPIARTAAKKIASLVFNEQAEIKVDDDAAN
                     KFISETLKNDRFNKNFERYLESCLALGGLAMRPYVDGDKVRVAFVQAPVFLPLQSNTQ
                     DVSSAAIVIKSIKTTNGKEVYYTLIEFHEWRSSNDYVISNELYRSDDKTKVGSRVPLS
                     EVYEDLKDEAEVTDVTRPIFTYLKTPGMNNKDINSPLGLSIFDNAKTTIDFINTTYDE
                     FMWEVKMGQRRVAVPESLTALTVRTADGDVVPRPRFESDQNVYIRMGGRDLDSSAIQD
                     LTTPIRADDYIKAINEGLLLFEMQIGVSAGLFSFDGKSMKTATEIVSENSDTYQMRNS
                     IVALVEQSLKELVISIFEIAKAYDLYQGEAPDMDNISISLDDGVFTDRDAELDYWIKV
                     VNAGFGTREMAIQKVLNVTEEKAQEIAAEINTGIVDEINQQRTDTHLYGE"
     gene            6634..8112
                     /locus_tag="VLL59_000648"
     CDS             6634..8112
                     /locus_tag="VLL59_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HER6508794.1"
                     /translation="MKKKPIKLNDEQLLLEASQLSDMYHQLTLDLFDQVIERIKARGS
                     ASLADNPYLWQANKLHEAGLLNADNIKLIAKYSSVAEAQLRHIIENEGVKIYKNTSEQ
                     LEEALGRESQVSSNIQDDLSNYARQAVDDVHNLINTTLPISVIGAYQGIIQDAVAGVV
                     TGLKTPDQAINQTVMKWFKKGFYGFTDKAERKWRADSYARTVINTTTWRVFNEAKEAP
                     AREFGIDTFYYSKKATAREMCAPLQHQIVTTGEAREEEGIKILALSDYRHGEPDGCLG
                     INCKHTKTPFVVGVNSKPELPEHLKNITPAQAKANANAQAKQRAIERSIRKSKELLHV
                     AKQLGDKDLISQYQSDVRNKQGALNHLVNSNDFLAESKSRSKMFVTDLMKREIVMKKG
                     LINDIIGLQTSDGITIKEISGHLLERIYERGVSESHIATALANPIYIRPDVVDEGGKV
                     SRRYVGNNVTVNINPHTGKVITTWKTGERTRRKYDNQRNVDK"
     gene            8084..8323
                     /locus_tag="VLL59_000649"
     CDS             8084..8323
                     /locus_tag="VLL59_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508795.1"
                     /translation="MTIKEMLISNQILNNDDIDFILSVNQDVSPLFELEDNDDNWDVL
                     VDELQQTSNYLTGDGESVSDRTKKFDDLVDKISAI"
     gene            8383..8652
                     /locus_tag="VLL59_000650"
     CDS             8383..8652
                     /locus_tag="VLL59_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508796.1"
                     /translation="MNKRIKKKRKLETVVMMLVAENAMQAEAIKSQNKEIMKLKSIVQ
                     RNAVATNEELATVKSATLDNQIAIKSVGDDVDYIKQNYKRKWGKK"
     gene            8863..9477
                     /locus_tag="VLL59_000651"
     CDS             8863..9477
                     /locus_tag="VLL59_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508797.1"
                     /translation="MHMENVTNENVDQETTDLENNQQEDKAFTQDDLNRVGTKEHSKG
                     YNKAVKDLGFDDVESAKDALKAFKEWQESQKSESEKQTEILNAKDKELEEARANNKAL
                     NAKLAAMSLGVNAESIDDVIALSERLVTDETSIEDAIKTVLGKYPHFGQTKDKAPKIT
                     VAGNPSADNGQGSVSKEDFAKMSYQEKLDLKLKNKNLYDQLKGN"
     gene            9481..10299
                     /locus_tag="VLL59_000652"
     CDS             9481..10299
                     /locus_tag="VLL59_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HER6508798.1"
                     /translation="MAVGTTKMAQMLDPEVLADMIDAEVGKAIRFAPLAEVDTTLEGQ
                     PGTTLTVPKWDYIGDAEDVAEGEAIPMTQLGFKKTTMTIKKAGKGVEITDEAILSGYG
                     DPVGQAAKQIVEAIDHKVDADVLDALSKSTQTVEATATVDGVSKALDIFNDEDDAETV
                     IVMNPADASTLRLDAAKEWLGATEVGANRVVSGVYGEVLGVQIVRSRKCPKGTAYMVR
                     KGALRIMLKRNTMVETDRDITKAINQIVANKHYGVYLYKAEKAVKITLKDAAKK"
     gene            10353..10769
                     /locus_tag="VLL59_000653"
     CDS             10353..10769
                     /locus_tag="VLL59_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508799.1"
                     /translation="MEVVIIAFLTQKEFEDLGFDEVEDFEKMEKRASHAVNLYCRNRY
                     DYKPFEKELIFIQKAVKRAVAYQIAYLSDSGVMTAEDKQSFAGISLGRTSISYTVGHG
                     QGSQQKTLADRFNLCLDAENELLAVGLGYTGISYDR"
     gene            10759..11091
                     /locus_tag="VLL59_000654"
     CDS             10759..11091
                     /locus_tag="VLL59_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HER6508800.1"
                     /translation="MIDKRLLIDKLQVKLVKDKGDYGGFVYDEPFALSPVRFDRNLAT
                     AGKDNARQEAKPSVIFIYPKYCKTVADRSWIDAVVIDGDTEYIVDKVIPVYHPLTNKV
                     FCFEVEVI"
     gene            11091..11447
                     /locus_tag="VLL59_000655"
     CDS             11091..11447
                     /locus_tag="VLL59_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HER6508801.1"
                     /translation="MAKIVVELGGIKRKVSPQALAKGKLIMNNQVMMSMNPYVPYRDG
                     ALRGSSRANSVGVTWSGPHARAQFYGGAYNKYKSFKFKKYTTPGTGKRWDKRALANAT
                     IVKDWEKSLLRGMGFK"
     gene            11444..11842
                     /locus_tag="VLL59_000656"
     CDS             11444..11842
                     /locus_tag="VLL59_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HER6508802.1"
                     /translation="MTNDFATVLRQFVEGLDLGIKPRLDYLTRQEDLAIYPMPGGKVN
                     NEYMDGTREISLPFEIAIKTKNQELASTVMWTINSALSNFDLKLPSLNNSYTFTSLDV
                     EKPFLNDLSDQGFYIYVLDITAHLEIEGNK"
     gene            11842..12327
                     /locus_tag="VLL59_000657"
     CDS             11842..12327
                     /locus_tag="VLL59_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6508803.1"
                     /translation="MARQKNALRGHFIAPYVKGEKTEVAKDKFLELAKWIKDISDDTD
                     EKTEDEAYYDGDGTEETTVVGVKGAYTFEGTYDPDDEAQKHIADMKYKTGDGRKVWHL
                     IVSAHEKKQWLGVATVTEIIAGSGAASDFEAFGCKITYNTLPEESTTLILDKKENSFE
                     M"
     gene            12373..12807
                     /locus_tag="VLL59_000658"
     CDS             12373..12807
                     /locus_tag="VLL59_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508804.1"
                     /translation="MSVINIDLKRTGFPVKIGVVELWFDTSQERLLEFFDIEAEIARR
                     LSEYEKQIIEANLGKKIEEEGVTKEIAKGALDLEAKYLEINYDLLFGEGTFNKLYEVY
                     PDKEALENTLEVVSREIEQKLDELKAERQKVVEEKVKKYKKK"
     gene            12816..13397
                     /locus_tag="VLL59_000659"
     CDS             12816..13397
                     /locus_tag="VLL59_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage Gp15 family protein"
                     /protein_id="HER6508805.1"
                     /translation="MKLNDRLIDSFEFRGKTYPINLSFNRVLDVFDVIKDTFLNEFEK
                     CLICIDILLDRDDLPLELSLELWIYIKEHFIDKERKQKPQLDIKGNPMPTLEKPEEHK
                     KIIDFTADASYIYASFRQAYQINLFKEHDRLHWMEFTTLLDALPDNSIMQRIIAIRQW
                     EDDGKGDKEHRNNMRKLKAKYSLDDGEEEDDGS"
     gene            13387..16647
                     /locus_tag="VLL59_000660"
     CDS             13387..16647
                     /locus_tag="VLL59_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015967413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HER6508806.1"
                     /translation="MAADGKVTILVDVDGKQVKVLNSELDKVAKHGDKGSSSLKKFAV
                     GAGVFKLASAAVDLVSQSLGKAITRFDTLEKYPRVMKAMGHSAEDVARSTDKLANGID
                     GLPTTLDEVVGTAQRLTSITKDINKSTNLTLALNNAFLASGASSEAASRGLEQYAQML
                     SAGKVDMQAWKTLQETMPYALQQTAEAFGFAGASAQKDFYEALKNGQITFDQFSNKLI
                     ELNDGVGGFAELAKENSKGIETSFNNIKNAIAKGVANSIKALDDLSKAATGKGIADHF
                     DSLKVVINASFSAINASIKASTPLFKLLFSVIGAGISVVKALSPALVGVASGLAAMRA
                     VNETITMIKALNRAWVMASASMSIGATTIKTVTAVQAVSTTMTKADMVARLSQLGVLK
                     ASTVIYGVMTGAISLSTAATIASTAAVTALKAALVALTGPVGWVVGAIGALVAVGVSL
                     WSWLTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKSLESIKESTAAHQKLAD
                     EIIKLAAKENKTAGEKQNLKNKIDQLNGSIDGLNLAYDKNSNSLSHNADQIKSRISAM
                     EAESTWQTAQQNLLNIEQKRSEVSKKLAENAELRKKWNEEANVSDSVRKEKIAELTEE
                     EGKLKNMQTQLQEEYNKTSATQQAAADAMAAAEESGSARQVLAYENMSEAQRTAIDNM
                     RTKYSELLETTTSIFDAIEQKTALSVEQMNANLEKNRAATEQWATNLEILAQRGVDQG
                     ILEQLRRMGPEGATQTQVFVDATDAELAPLQENFRTATETAKNAMGSVLDSAGVEMPE
                     KVKGMVTNVSTGLQAELQAANFAQLGQEIPNGVSQGISQGAGKASDASVKMGQEVKRS
                     FQGELGIHSPSRVFTEYGGHITDGLSNGVTNGTSKVMQTMQSLAQQMSQKGQQIVNDM
                     RNKSNQITDAFSTMSGPMHSHGVNAMQGLANGIYAGSGAALAAAQSIAARITATIQSA
                     LDIHSPSRVMRDEVGRFIPQGIAVGIDADRKVIDSSMQKLKESMTINATPEIASGFSG
                     GVAGIANQTTNNSNNSFTLNVKVDESDGNSREKYHRLFREFSWYIQQQQGRLGDVK"
     gene            16644..17360
                     /locus_tag="VLL59_000661"
     CDS             16644..17360
                     /locus_tag="VLL59_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HER6508807.1"
                     /translation="MTAFIKFDGKKSSDFDLRIINDVEHDSTFYDVDQIKVPGRDGVV
                     LKDNQRLEAVERSYPLRLYSKRRLTEVETDISDWLNVKGWKDLELSWEPDYIYKATHT
                     TPFSIKEVLRNFGSLRANFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQSKPILKIKG
                     TGNGVLTINGFETGLENVQGELLIDMERHLVYKDVLSAWDNIVRTERHRMPLFDVGQN
                     NISWTGNFTITAVPNWGVKV"
     gene            17357..19501
                     /locus_tag="VLL59_000662"
     CDS             17357..19501
                     /locus_tag="VLL59_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6508808.1"
                     /translation="MIPVLYEAKETRFRTFGLGEIADAYEVKVTRERNGNYSLYIKYP
                     LDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVNGASVGAESALGIWKENLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVVG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPFVR
                     YTPQPKPQEEASGKPHVSEHEQPEEQLVTLPEFILDGQYLELYAQRRIQMVDLSSHFN
                     DDKNKKEPTVEEIRKLAQKYLKDNNVGAPKVSIEVDYIDLSQTLDYQDFKVMEEVELC
                     DIVPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVSERINAL
                     ENNQKVIVNNQKQFELNLPKYLLDINGNRVWYEKPDDNIEHKIGDYWFEKNGKYQRTW
                     IWDGKQWVKVLDTEDLNFAQRAYDAAIAEFEKAKKAQEEINQRNQKELDEFRATLKNL
                     ALPEEAIKKITDAIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEIIGTDGKTRYNKN
                     LLVGDPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCELLQKVAVTLTQANNKGV
                     KLVLTPTKAKMEPQTFNLIKDKEVISVYPLSYTGILTGDWYKSKQIDLNASEVQELAL
                     EMDYKDVVDGKDATITGAWSDSPQIILDGGKK"
     gene            19498..20502
                     /locus_tag="VLL59_000663"
     CDS             19498..20502
                     /locus_tag="VLL59_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HER6508809.1"
                     /translation="MTETIPLRVQFKRMTAEEWARSDVILLEGEIGFETDTGYAKFGD
                     GKSRFSELKYLNKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIELNKKLNL
                     TGGIVTGQLRLKPNSGIKHSSSTGGAINIDMSKSKGAAMVMYTNKDTTDGPLMILRSD
                     KDTFNQSVQFVDYRGKTNAVNIVMRQPSTPNFSSALNITSANEGGSAMQLRGSEEALG
                     TLKITHENPSLKANYDKNAAALSIDIVKKTNGAGTAAQGIYINSTSGTTGKLLRIRNL
                     GDDKFYVEHDGGFYAKKTSQIDGNLKLKNPTASDHAATKAYVDDEVKKLKALLTNKQA
                     "
     gene            20515..22530
                     /locus_tag="VLL59_000664"
     CDS             20515..22530
                     /locus_tag="VLL59_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HER6508810.1"
                     /translation="MSRDPTLTLDESKLVIGPDDRMHYTFTAQDDNQKVRLASNCLGT
                     AHFNQVMIERGNKPTNYVAPVVVEGDGNPTGLFKDLKELNLELTDTANSQLWAKIKLN
                     NRGMLQTYFDTTIKNEILTTAQGIRETISDTERGLKSEFLKTVQGQRIRLESLLEQKT
                     AQLGLTVDGLRLDLNKADKQTASLQASINGLRQEYQDAERKLSASYQTGINGLKATMA
                     NDKYDLKAEIQATARGLSQEYDDKLHQLSAKIKTTSSGTTEAYENKLNSLRAEFTRSN
                     EGMRTELEYKITGLRAVQQTTASQISQEIKNHEGAVSRVQQDLNSYQRRLQNAEGNYN
                     SLRETVTGYERRISNQDNTISSNFTQLKTLIDQSVTLEKVQSLLRQSGDSIMLAIKDK
                     LPKSKMSGNEIISAINLNSHGVQIAGKNITLDGNTTVNGAFTTKIANAIKIKADQIIA
                     GVIDAAKIRVINLNASSIAGLDANFIKARIGYAITDLLEGKVIKARNSAMLIDLNSAK
                     LDFNSNATINFNNSNNALVRKDGTHTAFVHFSNATPKGYRGSALYASIGITSSGDGID
                     SASSGRFAGMRCFRQASGYNHTASVDQTEIYGDNVLIADDFNINRGFKFRPDKMPKMV
                     DMNNLYAAVVALGRCWGHLKNVGWNTTHSNFINAVNNELNTHVNKIN"
     gene            22539..22700
                     /locus_tag="VLL59_000665"
     CDS             22539..22700
                     /locus_tag="VLL59_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508811.1"
                     /translation="MQEKLLGKIINDLTIKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            22703..23311
                     /locus_tag="VLL59_000666"
     CDS             22703..23311
                     /locus_tag="VLL59_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HER6508812.1"
                     /translation="MRNWKVTGKYPQSDSTGAVASTYVVITDDDGAVIPQLIKQDLTS
                     TNDTETIKAVLEEFKKSEYVEIAMGEAVQKVDDLEKISQQTAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIEPVKKGEYQAYDVFTVVDEKHEDK
                     AGEGNLVFVHVNEPFTYEAQTLEELESEDKVTVIKYADLVKD"
     gene            23323..23598
                     /locus_tag="VLL59_000667"
     CDS             23323..23598
                     /locus_tag="VLL59_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508813.1"
                     /translation="MATELIFGVGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHAEQNKTLITMTEQIKNLTDDVKDLKDMMRGEVK"
     gene            23595..23822
                     /locus_tag="VLL59_000668"
     CDS             23595..23822
                     /locus_tag="VLL59_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HER6508814.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGVSDSEQALTYHEPKQ"
     gene            23938..25134
                     /locus_tag="VLL59_000669"
     CDS             23938..25134
                     /locus_tag="VLL59_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HER6508815.1"
                     /translation="MTFLDNIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYNSWNESILDHGKFLNENPRYK
                     SVIGETDYKKACHAIKDAGYATASGYAELLIQLIEENGLQEWDKEILTNQKEVTMTTA
                     NEIVKYCVDLANSGMGVDKDGAYGTQCCDLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQNSDTIVETPKTGTFTLDVAEINIR
                     RWPSLASEVVGSYKQGDTVSFDSEGYANGYYWISYLGGSGMRNYMAIGITDKDGNIIS
                     LWGKLV"
     gene            25392..25853
                     /locus_tag="VLL59_000670"
     CDS             25392..25853
                     /locus_tag="VLL59_000670"
                     /inference="COORDINATES: protein motif:HMM:NF024671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HER6508816.1"
                     /translation="MITALDVANTFLVRAKNENIDISPMKLQKLIYILYKVYLKETKK
                     RLFAEKFEVWKYGPVISDVYQVFKKYRSNKISDFYKKKDGSYTTVKLNNNPKFDKVFA
                     EVWDKYSRVDGIYLSQLTHQKDTAWSKADERNDYFLNDNEIFEESEYEIGA"
     gene            25837..26151
                     /locus_tag="VLL59_000671"
     CDS             25837..26151
                     /locus_tag="VLL59_000671"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508817.1"
                     /translation="MKLEPEKENMEDIPIEEDIPKQLPTSFQIDNENQPKVSKDMFNT
                     IKGHHLLGWCVGLLALVYGVETFAHKGDISSVGESFIEIIKLLIFSLTGYLFGTNSNN
                     KD"
     gene            26212..26391
                     /locus_tag="VLL59_000672"
     CDS             26212..26391
                     /locus_tag="VLL59_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HER6508818.1"
                     /translation="MLTYDEFKQAIDDGYIVGDTVKIVRKNGQIFDYVLPGEPVRLWE
                     VATEEKVEEVLMELW"
     gene            complement(26465..26788)
                     /locus_tag="VLL59_000673"
                     /pseudo
     CDS             complement(26465..26788)
                     /locus_tag="VLL59_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            27214..27783
                     /locus_tag="VLL59_000674"
     CDS             27214..27783
                     /locus_tag="VLL59_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HER6508819.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVATFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            27784..29736
                     /gene="gyrB"
                     /locus_tag="VLL59_000675"
     CDS             27784..29736
                     /gene="gyrB"
                     /locus_tag="VLL59_000675"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HER6508820.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            30104..31828
                     /gene="ezrA"
                     /locus_tag="VLL59_000676"
     CDS             30104..31828
                     /gene="ezrA"
                     /locus_tag="VLL59_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HER6508821.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(31960..32418)
                     /locus_tag="VLL59_000677"
     CDS             complement(31960..32418)
                     /locus_tag="VLL59_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HER6508822.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLNEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
     gene            32645..33952
                     /gene="eno"
                     /locus_tag="VLL59_000678"
     CDS             32645..33952
                     /gene="eno"
                     /locus_tag="VLL59_000678"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HER6508823.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERGVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(34433..35462)
                     /locus_tag="VLL59_000679"
                     /pseudo
     CDS             complement(34433..35462)
                     /locus_tag="VLL59_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(35729..37269)
                     /locus_tag="VLL59_000680"
                     /pseudo
     CDS             complement(35729..37269)
                     /locus_tag="VLL59_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT        12300 a         6477 c         8341 g        10222 t
ORIGIN      
        1 aaaaatgaag ttaacggttt tataaacgac ctgcgagaag atggtattaa atgtttagat
       61 atccaattca tttttgatga agatgagatc atcgtatttg ttaaatatga gggcttaatc
      121 gatgattgat ttctttatcc cgatgaagaa aatcccaact actacacatc aacaaaagaa
      181 ggtccgtgtg gtaaacggta aaccacaatt ctacgaaccg gattcgctga aggaagctcg
      241 tgccatgttt atgagtaaat ttgcacccca tgctcctgag aaaaaaatga ccggtccatt
      301 acgactcact gtcaaatggt tattcccacg tattaaaaaa tcaatagatg gtcagtacaa
      361 agatactaaa cctgacacag ataatttgaa caagctacct aaagattgta tgactgaatt
      421 gggattttgg aatgatgatg cgcaggttgc ttcggaaatt attgaaaagt tctgggctga
      481 tacagtagga atatatataa aggtggaaga gttatgaaaa ttgattatat taattttttt
      541 gaacgagtgg ttcctgactg gatgagagag agtaatgtca aaatgcaaga agttggattt
      601 aatactgaag cttattggat atgggccaac cagtcaattg ttacgatttg cgaaacttat
      661 ggtaacgact cattaattaa tggtcaattt catcttattt gggagtggct tgaaagtaaa
      721 acaaaagaaa gtagttaaaa atggtaaaac acgttgtgag agtttacaac aaaggtatta
      781 cagcgactta cgcgatctat gacaaaaacc tgtttcagga gcatgagttt gtaacaaaaa
      841 tagaagcgat gcagtttatt agagagctag agttagccaa tgataagcga gcgaatgagt
      901 attttttgag agaggtggaa ggatgacata tgtttttaga acaccaggag aaaactttaa
      961 agcgttagcg attaaggagt ttggtgacgc aattaaaaaa ccatcacatt atcaaggcag
     1021 gcatggcatg gaagcaatcg atgtggttaa aaacttcggg gcttgtccag agtacgagga
     1081 aggtttttat tggggcaatg ctgttaagta ccttttgcgg tatcacgcca aaaatggtgt
     1141 tgaagacctt aaaaaagcac ggcagaacct tgattggtta atcgaaaagt tggaggaagt
     1201 ggaatgaaga aaccaaatcg ctatccatac agtaaatcaa aatttaatgg ttgtatttac
     1261 cagttgcatt cagccagctt taaagatgaa caatatgtca aagatttaaa atcatgcggc
     1321 atacattatc aaatcacaaa atttggtcat tttcctgatg tttttataaa aattgataat
     1381 ctcgaacaat tacaagcatt aatagataaa acaggacacg atttaatact tagtaaaaac
     1441 gaaatttgga tttatgatga ctatatggaa tgaggagtaa taatgacaac agatgaatta
     1501 ttgcaaaatt tacgtgataa cttgaataaa ataatgaatg tcctaaaaag cgactggaaa
     1561 gcactattgt ttcttacgat cgcaatattg ggaatgatgg taactgtgtc gtactttagc
     1621 tatcgtgatg cacaacaata ttacgagccg caaatatacg gactgcgcgc tcagctaagc
     1681 aggacacaaa agcagcttaa gcgtgcgagt gaggatagag ctagacagac aaagcggata
     1741 gcggaaatga ctgggaatgg gggatgaaat atgccagaat tgattaacac agccgactta
     1801 cagacaccga tagaagcact agaagataac ctagattttt ttaaaggttt ttacaacgac
     1861 gaacgctttg aagatatgga aaatgcaaaa aaattgattg agagatacga aaaagctata
     1921 tcaattttaa ccgaggtaca aaatgaaagt taaagattta cataaagtgt tagctaaagt
     1981 tgaccctgaa cttgaagttt ggataaatga aaaagatgga ggggttataa ctaaagctaa
     2041 aaacgtgatg acttggaatg agcatccaaa taagtttttt ataaatgcag aaacacaata
     2101 atgttaaccg aggtagcaaa tgaatattga agaagcgaaa gaaaagatta aagaaatatc
     2161 ttatggcact ggtatatttt taacaaatta cgaagttaac tcaaaaaaag tcttagaaat
     2221 cctcgaccaa ctcgacaaac caaaaccaga agtcccgcag tttgttgctg attggataga
     2281 agagtgcgaa gaagaaggtt taactttaaa aggcttgttt tctaacagcg atatgcctgc
     2341 aaaaattttt gattggattt ttggtagtga cgaaaattgt aggttaatgg ctgaagcatg
     2401 gattaacggc tacacagtag aaaaagaaaa gctctacact gtcgacttac caaacggtca
     2461 acctttagtg cgcggcataa acactttgta ttttagtcaa aatctagcaa ccgaaaatgt
     2521 aaaactcacc gaatccgaaa tccgcaaaga ttttgaatgg gcgtggcagt ttgctgaaga
     2581 ggtgacggga tgagtagatt atctaatgca caattaaaag cttttgatga atggttgttt
     2641 gattatcgtg aaataggacg aaaaattgca cttcgaaaac ttgaactaca gacgccagtt
     2701 agtacagata tcaacgcagg tggcggcaaa gctaatctag tagctaaaga gacggaagat
     2761 attgttgtga agtggtccga ggacggtaaa atcaaaagtt atgagaactt cagagaaagt
     2821 gtcgataggg ttaaagcact gcttgacaaa gagctgaccg aaatattcga attgagatgg
     2881 ggagtaggtt ctaacaatac ttgggaggag atagcttata agattcatac gtctagggca
     2941 ggaacctacc gaaaaaggga tagaatattg accttatttg cccaagaaat tggaaaattg
     3001 taaggttgag acaaaaaagg gtggttttct cacttttttg atgataaatt gatagtatga
     3061 gtttaaaggt aaggcaaata gtgtcttgcc tttttagttt acaaaacgaa caaataggag
     3121 gtgtaagatt gggcagagca cgagacccaa accgagataa agcttttgaa ctttacaagc
     3181 aaaataacgg agacatcact aaccgcaaac tcggtgaaat gttgggtgtg cctgaaaaaa
     3241 caatctcagt ttggaagcta agagataagt ggaaagaatg tagtactaca aagaatagaa
     3301 gtactgcgaa acgcccgagg ggggcgccta agggcaataa gaatggtaaa ggcggaaccc
     3361 ttgggaacac aaacgccctt aagcacgggc tatttgctaa gtatctacca aaaggggtct
     3421 acgaaataac tcaggatata gagtcaaagc cccccataga catactttgg gacaacataa
     3481 ctctaaccta tgcgaatctt cttcatgccc agaaaatatt acatgtgacc gatcagcagg
     3541 accacgccaa ctttatcaca agcgagggta aagctgggat tggatatgag cggcacactt
     3601 cttgggacag gcagactaat gctttgactg ctattgcaag ggttcaagct gagttacgca
     3661 acatgatcaa gacctatgac gagttaacac gtagcgagct tgtcactgac gagcagcgaa
     3721 cacgtattga actacttaaa gtcaagctcg atgctgaaaa aggctctaag cctgatacaa
     3781 gcttgatgga agcattgtta gatgctgtgg aagggggtga ttaaccttgg agattatctt
     3841 ttcaaataaa caaaaagaca tcattagacg cccttttaac tacgaattag aggtcaatga
     3901 ggggacaccc agaagtggaa agaccaccgc tgggcatttt cgttatgcta ggtatctgat
     3961 tgagtcagaa gatgaaaatc atcttgtgac ggcttacaat caagaacaag cttatcgttt
     4021 atttattgat ggagacggta cgggcttgat gcacatattc gatggtaact gtgaaatcaa
     4081 acacgatgaa cgaggagatc acttgttaat catgacacca aaaggtaata agcgtgtcta
     4141 ttacaaaggc ggcggtaaag ttaatagcgt tggtgctatc acaggtatgt ctctaggctc
     4201 agtggttttt tgtgagatta acttactgca catggatttt atccaagagt gttttagacg
     4261 gacttgggcg gctaagctac gatatcactt agcggacctt aacccgcccg cgccacaaca
     4321 ccccgtgatt aaagatgtct ttgatgtgca aaatacaagg tggactcatt ggactatgga
     4381 tgacaacccc atacttacag tcgagcgtaa gcaaaacatc attaatagtc ttaaaaaaaa
     4441 tccatatctg tacaagcgag acgtactcgg acagcgtgtc atgcctcagg gggttatcta
     4501 tggccttttt gacatggaaa aaaatgttct agacactttt attggcgagc cagtggagat
     4561 gtatttctgt gcagatggtg ggcaatctga tgccacctct atgtcttgta atatcataac
     4621 gagagttaga gataatggca aaataagctt tagacttaac cgagtagctc actactatca
     4681 tagtggagca gatactggtc aagtaaaagc tatgtcaacc tacgcaatag agttaaaagt
     4741 ttttatggac tggtgcgtta aaaagtatca gatgcgctat acagaggtgt ttgtagaccc
     4801 tgcctgtaaa tccttgagag aggagctgca caagctagga gtatttactc tgggagcccc
     4861 gaacaattct aaagatgtat ctagcaaagc caaaggcatc gaggttggta tcgagcgtgg
     4921 ccaaaatata atctcagatg gcgcttttta tcttgttaat catagcgagg aagagtatga
     4981 ccactaccac tttttaaaag agatagggct gtacagtcgt gacgacaatg gcaaacctat
     5041 tgataaagat aaccatgcca tggacgagtt tagatatagc gtcaacgtgt ttgtgcatcg
     5101 gtattacaac taaaggagtt gcttaaatgg gagtaatcca aaaaataaaa aatcttgtta
     5161 caaggagtaa atacgtgatg acaacgcaga gtcttacaaa tataactgat catcctaaaa
     5221 tagctatcag tcagctagag tacgaccgta taacaaccaa tctaaagtac tataagagcg
     5281 attgggatag tgttttatac ttaaacacgg atggcgagac taaaaaaaga aatcttaacc
     5341 atctgccaat tgcacggacg gccgctaaaa agattgctag ccttgtcttt aatgagcaag
     5401 cagagattaa ggttgatgat gatgcggcta ataaatttat tagtgagaca ctaaaaaacg
     5461 accgttttaa taaaaacttc gagcgatatc tcgagagctg tctagccttg ggtggcttag
     5521 ccatgaggcc ctacgttgat ggcgacaaag ttagagtagc gtttgtccaa gcgcctgttt
     5581 ttttgccact acagagcaac acgcaggatg tttcaagcgc tgctattgtt attaagtcca
     5641 ttaagacaac caatggcaaa gaggtctatt atactttgat agagttccat gaatggcgca
     5701 gctctaatga ttatgttatc tcaaatgagc tatatcgctc agatgataaa actaaggtag
     5761 gtagccgagt gccgttatct gaggtatacg aggacttaaa agacgaggct gaagttacag
     5821 atgtgactag gcctatcttt acttatctca agacccctgg aatgaataac aaggatatta
     5881 atagtcctct aggcttgtca atctttgata atgctaagac aacgattgac tttatcaata
     5941 cgacctatga cgaatttatg tgggaagtta agatgggtca acgtcgagtt gctgtgccag
     6001 agagcttgac tgctttaact gttcgtaccg ctgatggcga tgttgttcca agacctcgct
     6061 ttgagtctga tcaaaacgtt tatatccgta tgggaggcag ggatttagac tcaagcgcaa
     6121 tacaggacct aacaacacct attagagcgg atgactatat caaggccatc aacgaggggt
     6181 tgttgttatt tgagatgcaa ataggggtat ctgctggact atttagtttt gatggcaaga
     6241 gcatgaagac tgcaacagaa atcgtctctg aaaactcaga cacgtatcaa atgagaaata
     6301 gcattgtcgc tttagtagag caatcgctaa aagagttagt tatctcaatt tttgagattg
     6361 ccaaagctta tgatttgtac caaggcgaag ctcccgacat ggataacatc agcataagtc
     6421 ttgatgatgg tgtttttaca gatcgagatg ctgagttaga ctactggata aaagttgtta
     6481 atgctggctt tggcactcgt gagatggcca tccaaaaagt gctaaacgtg acagaggaaa
     6541 aagcccaaga aatagctgca gaaattaata ctggaatcgt tgacgaaatc aatcaacagc
     6601 gcactgatac acatttatac ggagagtgat tagatgaaaa agaagcctat taagttaaat
     6661 gacgaacagc ttcttttgga agctagtcag ttatctgata tgtaccatca gctgactctt
     6721 gatttatttg atcaagtgat tgagaggata aaagccagag gctcagcgag cttagccgat
     6781 aatccttatc tttggcaagc taataagtta cacgaagctg gactgcttaa tgcagataat
     6841 attaaactca ttgcaaagta ttctagcgtt gctgaagctc aacttcgtca tatcatcgaa
     6901 aatgaggggg ttaaaattta taaaaataca tcagaacagc tagaagaggc tttgggtaga
     6961 gagtcacaag ttagcagtaa tatccaagat gacttatcta actatgccag acaggctgtt
     7021 gatgatgtgc ataatttgat taacaccacc ttaccaatta gtgtcatagg agcttatcaa
     7081 gggataatcc aagacgctgt tgctggtgtt gtgacaggct taaaaactcc tgaccaggct
     7141 atcaatcaaa ctgtgatgaa gtggtttaaa aagggttttt atggctttac agataaagca
     7201 gagagaaagt ggagagcgga ctcttatgct cgtactgtta tcaataccac gacttggcga
     7261 gtctttaatg aagccaagga agcacctgct agggagtttg gcattgatac cttttactac
     7321 tcaaaaaaag ctacagctag agagatgtgt gcgcctttgc aacatcaaat agtcaccact
     7381 ggcgaagcga gagaagaaga gggaataaaa atcttagctt tatctgatta caggcatggt
     7441 gagcctgacg gatgcttggg aattaactgc aagcacacta aaacgccgtt tgttgttggt
     7501 gtgaatagta agccagaatt gccagagcac ctaaaaaata ttactcctgc acaagctaaa
     7561 gctaatgcga atgcgcaagc taagcaaagg gcaattgaga gatcgatccg taaaagcaaa
     7621 gagctactgc atgttgcaaa gcagttgggt gataaagatt tgattagtca atatcaatca
     7681 gatgtcagga ataaacaagg tgcacttaat caccttgtca atagtaatga ctttttggca
     7741 gaaagtaagt ctaggtctaa aatgtttgtc acagacctga tgaagcgtga aattgtgatg
     7801 aaaaaagggc taatcaatga tataataggc ttacagacaa gtgatggaat tactataaaa
     7861 gaaattagcg gacacttact ggaaagaatc tatgagaggg gcgtctctga aagtcacatc
     7921 gctactgcat tggctaaccc tatttacatt agacctgatg tagtagatga aggtgggaaa
     7981 gtttcaaggc gctatgtagg caacaatgtc accgtcaata ttaacccaca tacaggtaag
     8041 gttataacta cttggaagac tggcgaaaga acaaggagga agtatgacaa tcaaagaaat
     8101 gttgataagt aatcaaatat taaataatga tgatattgat tttatattat ctgtaaatca
     8161 agatgtctct cctttgtttg agcttgaaga taatgacgat aactgggatg tattagtgga
     8221 cgagttacag caaacctcta attacttaac gggagatggc gaaagcgtct cggatagaac
     8281 taagaagttt gatgatctag ttgataaaat atcagcaatt taatcttata agcatttagc
     8341 taaaagctag gtgcttttct tatgcttaaa aaggagaagg cgatgaataa acgcattaag
     8401 aaaaaacgta agttggaaac agttgtgatg atgcttgttg cggaaaatgc tatgcaagca
     8461 gaagcaatta agagtcaaaa caaagaaatc atgaagctaa aatcaatcgt tcaacggaat
     8521 gctgtagcaa caaacgaaga gttagcgact gttaaatcag cgacgctaga taaccaaata
     8581 gctatcaagt cggttggtga tgatgttgac tatatcaaac aaaactataa gcgtaagtgg
     8641 ggtaagaaat gaaatatctc acttggttaa tttataactt ggctgtcttg gtcatgacct
     8701 gttggctaat ccacgttttc catagcggat ggtggatttt gctcccattt tttatgttaa
     8761 ccacatttaa acaaaagtcg tagcaatacg gctttttatt gcgcctttat ccgcaggcgt
     8821 taaagaacgg aaattagcga cctatcgctt ttataggagg gaatgcacat ggaaaatgtg
     8881 acaaatgaga acgtcgacca agagactact gacttggaaa ataatcaaca agaagataaa
     8941 gcatttacac aagatgatct gaatcgagtg ggaactaaag agcactctaa aggctataac
     9001 aaagcagtca aagacttagg ttttgatgac gtggaatcag ccaaggatgc actaaaagcc
     9061 ttcaaagagt ggcaagagtc acaaaaaagc gagtcagaaa aacagacaga aatcttgaat
     9121 gctaaagaca aagagcttga ggaagctcgg gcaaacaata aggctcttaa cgcaaagcta
     9181 gcagcaatgt ctttaggtgt gaacgctgaa tctattgatg atgtgattgc actatctgag
     9241 cgtcttgtca ctgacgagac aagcatagag gatgcaatca aaacggtttt gggtaagtat
     9301 cctcactttg gccaaacaaa ggataaagct cccaaaatca cagtggcagg caacccgtct
     9361 gctgataacg gacaaggttc ggtgtctaag gaagactttg caaagatgtc ttaccaagaa
     9421 aaactggacc taaaactaaa aaataagaat ctttatgacc aactgaaagg aaattaaaaa
     9481 atggcagtag gaacaactaa aatggcacaa atgctagacc ctgaggttct agcggatatg
     9541 attgacgcag aggtagggaa agcgattcgc tttgctcctc ttgctgaagt agatacaact
     9601 ttagaaggac aaccaggtac aactttaaca gtgcctaaat gggattacat cggtgacgca
     9661 gaagatgttg ccgagggtga agctatccca atgactcaac ttggcttcaa aaagactact
     9721 atgaccatta aaaaagccgg aaaaggtgta gaaatcactg acgaagctat cttatctggg
     9781 tatggggatc ctgtaggtca ggcagcaaag caaatcgttg aggctattga ccacaaagtc
     9841 gatgcagacg tgcttgacgc gttaagtaaa tcgactcaaa ctgtggaagc tactgctacg
     9901 gttgatggtg tatctaaagc gctagatatt tttaatgacg aagatgacgc agagacagtc
     9961 attgtcatga atccggcgga tgcctctacc ctacgtttag atgccgcgaa ggagtggtta
    10021 ggtgctaccg aggttggagc aaatcgtgtt gtctctggtg tttatggtga agttttaggg
    10081 gtacaaattg tgcgttctcg caaatgccct aaaggaactg cctacatggt tcgcaaaggt
    10141 gcactacgta tcatgcttaa acgtaacaca atggttgaaa cagaccgaga tatcacaaaa
    10201 gcgattaatc aaatcgtagc taataagcat tatggtgttt atctttataa ggcagaaaaa
    10261 gccgtcaaaa ttacacttaa agatgccgca aaaaagtagc taaggctaag gctgccaaga
    10321 gagaggaaga tgacgctctc gagtcttagc cgatggaggt ggttattatc gcttttttaa
    10381 cgcaaaaaga atttgaagat ttgggttttg acgaggtaga agattttgaa aaaatggaaa
    10441 aacgtgctag ccacgctgtc aatctttatt gtcgcaatcg ctacgattac aagccttttg
    10501 aaaaagaact aatctttatc caaaaggcag ttaaaagggc agttgcctat caaatagctt
    10561 acttgagtga ctcaggagta atgacagcag aggataaaca atcctttgct ggaatatctc
    10621 taggacggac aagtattagc tacactgtcg gacatggcca aggcagccaa caaaaaactc
    10681 tggctgacag gtttaatctc tgtctagatg cagagaatga gttgctagct gttgggttag
    10741 ggtatacggg tattagctat gatcgataaa agactgctta ttgacaaact gcaggtaaaa
    10801 cttgtcaaag ataaaggtga ttatggagga tttgtctatg acgaaccttt cgccctctct
    10861 cctgttaggt ttgaccgtaa tcttgcaacc gcaggcaaag acaatgcaag gcaagaggct
    10921 aagccgtccg tcatatttat ttatcctaaa tactgtaaga ctgtagccga taggtcatgg
    10981 attgatgctg ttgttattga tggcgataca gagtatatcg ttgataaagt gataccagtc
    11041 taccacccac tcacaaataa ggttttttgt tttgaagtgg aggttatcta atggccaaga
    11101 tagtggtaga gttgggaggc attaagcgta aagtatctcc gcaagcttta gctaaaggaa
    11161 agctcatcat gaacaaccaa gtcatgatgt cgatgaaccc ttatgttcct tacagagacg
    11221 gagctttgag aggaagctcg agagccaata gcgtaggtgt aacatggagt ggtccgcatg
    11281 caagggctca attttatggc ggtgcctaca acaagtacaa gtcctttaaa tttaaaaagt
    11341 acacaacacc aggtacaggc aagcgttggg ataaacgtgc gttagctaat gctacaatcg
    11401 tcaaggattg ggaaaaatcc ttgctgagag gaatgggttt taaatgacaa atgactttgc
    11461 aactgttttg aggcaatttg ttgaaggatt agacttaggt ataaagccta gacttgacta
    11521 tctaacaaga caagaagacc tagccattta tccaatgcca gggggtaagg taaataacga
    11581 gtatatggac ggtactcggg agataagtct gccttttgaa attgcaatca aaactaaaaa
    11641 tcaggagtta gcaagcactg tgatgtggac tattaacagt gctttgtcta actttgactt
    11701 gaaattacca agtcttaata attcgtatac atttactagc cttgatgttg aaaagccttt
    11761 tttaaatgac ttaagcgacc aaggctttta tatttatgtg ctggatatta cagcacacct
    11821 agaaatagaa gggaataaat aatggcaaga caaaagaacg ccctacgtgg gcattttatc
    11881 gcaccatacg ttaagggtga aaaaacagaa gttgcaaagg ataaattcct agaacttgcg
    11941 aagtggatca aggatatctc tgacgatacc gacgaaaaaa cagaagatga agcgtattat
    12001 gacggtgacg gaaccgaaga aaccactgtt gttggtgtaa agggtgccta tacttttgag
    12061 ggtacctacg atcctgatga tgaagcgcaa aagcacattg cggatatgaa gtataaaaca
    12121 ggagacggcc gaaaggtttg gcacttaatt gtgtcagccc acgaaaaaaa acagtggttg
    12181 ggggtagcaa ctgttacaga aattattgct ggctctgggg ctgcatctga tttcgaggca
    12241 ttcggttgta aaatcaccta caacactctg cctgaagaaa gcactacgtt aatcttagac
    12301 aagaaagaaa atagcttcga gatgtaatag agtcagcgta agctggctct tattttttga
    12361 taaggagatg acatgtcagt aatcaatatt gatcttaagc gtacaggttt ccctgtgaaa
    12421 attggagtag ttgagctttg gtttgacaca agtcaagagc gactccttga attttttgat
    12481 atcgaagctg agattgcacg tcgattaagc gagtatgaaa aacaaatcat tgaggcaaat
    12541 ctcggcaaaa aaattgaaga agaaggtgtt actaaagaaa ttgctaaggg tgctttggat
    12601 ttagaagcta aatacctaga aattaactat gacttactat ttggagaggg tacttttaat
    12661 aaactttacg aagtctaccc tgacaaagaa gcgttagaaa acactcttga agtggtctct
    12721 agagaaattg agcagaagct tgatgaattg aaagccgaac gtcaaaaagt agtggaagag
    12781 aaggtgaaaa aatacaaaaa gaagtgaggt agcttatgaa actaaacgat cgattgatag
    12841 attcgtttga gtttagaggc aagacctacc caattaactt atcttttaat cgtgtgctag
    12901 atgtttttga cgtgattaaa gatacttttt taaatgagtt cgaaaaatgt cttatctgca
    12961 ttgatatctt gctagataga gatgatttac cattagaatt gtcgcttgag ttgtggattt
    13021 acataaaaga acactttatc gacaaagaaa gaaaacaaaa accacagctg gatatcaagg
    13081 gcaaccctat gcctacactg gaaaaaccag aagagcataa gaagataatc gattttaccg
    13141 cagatgcgag ctatatctac gctagtttta ggcaagcata tcagattaat ctctttaaag
    13201 agcatgatcg cttgcactgg atggaattta caacgctgtt ggacgcactg ccagacaact
    13261 ctattatgca gcgcattata gctatcaggc agtgggaaga tgatggtaag ggagataaag
    13321 aacatagaaa taacatgcgt aaattaaagg ctaagtatag cttagatgac ggagaggagg
    13381 aagacgatgg cagctgatgg taaggtaacg atacttgttg acgttgatgg taagcaggta
    13441 aaggtgctca atagtgagtt agataaagtt gctaagcatg gtgacaaagg aagctcctct
    13501 cttaaaaaat ttgcggttgg tgcaggagta tttaaattag cttcggctgc agttgatttg
    13561 gttagccaat ctcttggtaa ggccattaca aggtttgaca cactcgaaaa atatccaagg
    13621 gtgatgaaag caatgggcca tagcgctgag gatgttgcaa ggtcaacaga taagctggct
    13681 aatgggattg atgggctgcc aacaactcta gacgaggttg tcggaactgc tcaacgcttg
    13741 acctctatca ctaaagatat caataagtcg accaatctca cgctagcttt aaacaatgcc
    13801 tttttagctt caggagcttc atcagaggct gccagtcgag gtctagagca atatgctcaa
    13861 atgttatcag ctggtaaggt tgatatgcaa gcttggaaaa ctctccaaga aacaatgcct
    13921 tatgctttgc aacaaactgc ggaagctttt ggatttgcag gagcatcagc tcaaaaggat
    13981 ttttatgagg cgttaaaaaa tggccaaata acattcgatc aattttccaa caagttgatc
    14041 gagttaaatg acggtgtcgg tggttttgca gaattagcaa aggaaaatag taaagggatt
    14101 gaaacctctt ttaacaatat taagaatgcc attgcaaaag gtgtagccaa tagcattaag
    14161 gctttagatg atttatctaa agccgcaaca ggcaagggta tagctgatca ttttgatagt
    14221 ttgaaagttg ttatcaatgc ctcttttagc gccatcaatg caagtattaa agctagtaca
    14281 ccgctattta aactattgtt tagtgttatt ggggctggaa tatcagtcgt caaagctctg
    14341 tcaccagccc tggttggtgt agcatctggt ctagctgcta tgagggcagt taatgagacc
    14401 ataacaatga ttaaagcgct aaacagagct tgggttatgg catctgcatc aatgagtatt
    14461 ggagcaacaa ccattaagac tgtgactgcg gtacaagcgg taagtaccac gatgactaaa
    14521 gctgatatgg tcgcaaggct gtctcagtta ggtgtcttaa aagccagtac agttatttat
    14581 ggcgttatga caggagctat tagcctatct accgctgcaa ccatagccag tactgctgcg
    14641 gtaactgctc ttaaagcggc gcttgtagct ttaacaggcc cagttggttg ggtagttgga
    14701 gctatcggtg ctttggttgc tgttggagta agtttgtggt catggctaac taaagagtca
    14761 gacgagacca agaagctgaa aaaagagcag gaggggctag tcgaaagcaa caaacagcta
    14821 agagattctg tccgtgaggg cgtgcaagag cgtaagaaga gccttgagtc catcaaagag
    14881 agcactgcag cccatcaaaa actagccgat gaaattatta agctagcagc caaagaaaac
    14941 aaaactgcag gcgaaaaaca aaacttaaaa aataagattg atcagcttaa tgggtctatt
    15001 gatggcttaa acttggctta tgacaagaat tccaattctc tttctcataa tgcagatcaa
    15061 attaagtcac gcattagtgc catggaagca gaaagcacat ggcagacagc acaacaaaac
    15121 ctgttaaata ttgaacagaa acgtagtgag gttagtaaaa agctagctga aaatgccgag
    15181 ctacgtaaaa agtggaatga agaagctaac gtctccgatt ccgtccgaaa agaaaagatt
    15241 gccgaactca cagaagaaga gggcaagctt aaaaacatgc agactcaact gcaggaggaa
    15301 tataacaaga catcagctac tcaacaagct gctgcagatg ctatggctgc cgctgaagaa
    15361 tcaggatccg caagacaggt tttggcctat gaaaatatgt cggaagctca acgaactgcc
    15421 atagacaaca tgcgcactaa gtactcagag cttttagaga caacgacatc tatttttgat
    15481 gctatcgagc aaaagacagc tctgtcagtt gagcaaatga atgccaacct cgaaaaaaat
    15541 agagctgcta ctgaacaatg ggctacgaat ttggaaattt tagctcagcg tggtgtagac
    15601 caaggtatct tagaacagct taggcggatg ggccctgagg gggcaacaca gacacaggtt
    15661 tttgtggacg ccacagatgc agaattagct cctttacagg aaaactttag aacagccaca
    15721 gaaactgcta aaaacgccat gggaagcgtg ctggactcag caggcgtgga aatgccagaa
    15781 aaagttaaag ggatggtcac taatgtttct acgggattac aggcggaact gcaagctgct
    15841 aactttgctc aacttggtca agaaatccct aatggggttt ctcaaggtat aagtcaaggg
    15901 gcaggtaaag caagtgacgc aagtgtcaaa atgggtcaag aagttaaacg ctctttccaa
    15961 ggagagttgg gtatccactc gccatcgcga gtatttactg agtacggtgg acatattact
    16021 gatggcttga gtaatggtgt gacaaatgga acgtcaaaag ttatgcaaac catgcagagc
    16081 ttggctcaac agatgtctca aaaaggacag cagattgtta atgacatgcg taacaagtcg
    16141 aaccaaatca cagatgcttt tagcacgatg agtggcccaa tgcactctca tggtgttaat
    16201 gccatgcaag gtttggctaa tggtatttat gcagggtcgg gggcagcttt agcggcagct
    16261 caaagcattg cggcacgtat caccgcaaca attcaaagtg ccttagatat ccactcgcca
    16321 tctcgtgtta tgagggatga ggttggacgt tttatccctc aaggtatcgc tgtaggtatt
    16381 gatgcggata gaaaagtcat tgactcatct atgcaaaagc taaaagagtc gatgacgatt
    16441 aatgcgaccc cagaaatagc ctctgggttt agcggaggag ttgcagggat tgctaatcag
    16501 accacaaata actcaaataa cagtttcacc cttaatgtca aggttgatga atcagacggt
    16561 aatagccgcg agaaatatca ccgcttattc agagaattta gctggtatat tcaacaacaa
    16621 caaggaaggt taggtgatgt taaatgacag cttttatcaa gtttgatggt aaaaaatctt
    16681 cagattttga tttgagaatt attaatgatg tcgagcatga ctcgaccttt tatgatgttg
    16741 accagattaa agtacctggt cgtgatgggg ttgttttaaa ggataaccaa agactcgaag
    16801 ctgtcgaacg ctcttatcct ttgcgcttgt atagtaaaag gcgattgaca gaagtagaga
    16861 ccgacataag cgattggctt aatgtaaaag gctggaaaga cttggagtta tcttgggaac
    16921 ctgactatat ctataaagca acacatacca ctccttttag tataaaagag gtcttacgta
    16981 actttggaag tttaagagct aactttttaa tccaccctat caaatattta aaaacaggta
    17041 agcaagaggt gcctctcgta aatggaggta ctctacaaaa tcctggcaat gtccaatcta
    17101 aacctatctt aaaaatcaaa ggcacaggca atggcgtctt gaccattaat ggctttgaaa
    17161 ctggacttga aaatgtgcag ggtgagcttc ttatagacat ggaaaggcat cttgtctata
    17221 aagatgtctt atccgcttgg gataatatcg tgcggacaga gcgccacagg atgcctttat
    17281 ttgacgttgg tcaaaataac atctcgtgga ctggtaactt tacgatcacc gcagtaccaa
    17341 actggggggt taaagtatga taccagtttt atatgaggct aaagagacca ggtttaggac
    17401 ttttggtctt ggagagattg cagacgctta cgaggttaaa gtcactcgtg agcgtaatgg
    17461 caattactca ctgtacataa aatatccact agatggtgtc ttcgcctcag tttttaaaga
    17521 ggaaatgaag attaagtctg acgctggtcg taggactaag tggcaaactt ttgagattaa
    17581 tcgggtacta cgaaatagta aagaccacat tgagattttt gcgcgacaca tctcaatgcg
    17641 cacacaagat attgctttaa agccatttgt aaacggtgcg agcgtaggcg ctgaatcagc
    17701 tctaggaatc tggaaggaaa accttgttgg tgatgacact tttgatgtca aaagcgacat
    17761 cctaacgctt ggtagtttta attgggaagt ggataaaatt ggcaatgcca gaggtgctct
    17821 aggaggtgtt gttggctcaa tcttggatgt ttatggtggt gagtatgaat ttgacaatcg
    17881 cactatcatc ttacacaaac aaatgggtcg taaagctcct actgtgttgg agtatggccg
    17941 caatatcgtc agcgtagagg aggagcgatt gcttgatggc aattacacct ctatttatcc
    18001 atttgttaga tacacgcccc agcccaaacc gcaagaggaa gcctctggta agcctcacgt
    18061 aagcgagcat gagcaacccg aagaacaact ggtgacacta cccgagttta tcctagatgg
    18121 tcagtatctt gagttatatg cccagcgcag aatccaaatg gttgatttat caagtcattt
    18181 taacgatgac aaaaataaaa aagagccaac agtcgaagaa attagaaagc tagctcagaa
    18241 gtaccttaag gataataacg taggtgcccc taaagtcagc attgaggttg attatatcga
    18301 cctgtcacaa acacttgact accaagattt taaggtcatg gaagaggtcg agctttgcga
    18361 tattgtgcct ctttactatc caaaatttgg catcacaacc gagaccgaaa aagtagtgga
    18421 gattgtctat gacgtctata cagatagcaa tcacacgatc aagcttggga caatcgggca
    18481 gtccatctcg aaaagtttga ctggcggtgt gtccgaacgt attaatgcgc tggaaaacaa
    18541 ccaaaaagtg attgttaata accagaagca atttgagctt aacttgccta aatatctcct
    18601 agacatcaat ggtaaccgtg tctggtacga aaaaccagat gacaatattg agcacaagat
    18661 aggtgattac tggttcgaaa aaaatggtaa gtatcagcgc acttggattt gggatggcaa
    18721 gcaatgggtt aaagtactag atactgagga tttgaatttt gctcaaaggg cctatgatgc
    18781 cgcaatagcc gaattcgaaa aagccaaaaa agcgcaggaa gaaatcaatc aacgcaacca
    18841 aaaagaactc gatgaattcc gagccaccct caaaaaccta gcgttaccag aggaagccat
    18901 caaaaaaatc acagatgcta tcaaggtcga tgacatccca tcaattaaac aaagctttga
    18961 tgacctcaaa aacaaagtca gcgagacgag cgagacatcc cgtctaaacg ccgaaatcat
    19021 aggcacagac ggtaagaccc gctacaacaa aaacctcttg gttggcgatc ctaatcgtgt
    19081 taaaaaaatt gatgaggatt ttatcgaggt cgaagccaat gacggtggtt ttaaacgtgg
    19141 tgagacatac acgataagct ttagtcagac ttgtgagctg ctccaaaaag tggctgtcac
    19201 gctgacacag gctaacaaca agggagttaa gttagtactg acaccaacta aagcaaaaat
    19261 ggagccgcag acctttaatc taatcaagga taaagaagtt atcagcgttt atcctttgag
    19321 ctatacaggc attttaacag gtgattggta taaatctaag cagatagatt taaacgcgtc
    19381 ggaggtgcag gaattggctc tggagatgga ttataaagat gttgttgacg gcaaggatgc
    19441 cacaataaca ggggcatggt cagacagtcc acaaataatt ttagatggag gtaaaaaatg
    19501 acagaaacta taccgctacg agtccaattt aagcggatga ctgccgaaga atgggctcgc
    19561 agcgatgtca tcttacttga gggtgagata ggctttgaga ccgacacagg atatgctaag
    19621 tttggtgatg gtaaaagccg atttagtgag cttaagtacc ttaataaacc agatctaggt
    19681 gcgtttgcac aaaaagaaga aactaatagt aaaatcacca aattagaatc aagcaaagca
    19741 gataaaaacg ctgtttactt aaaagcagag tcaaaaatag agctaaacaa aaaattgaat
    19801 ttgacaggcg gcatagtgac aggacaacta cgacttaaac ctaatagtgg tattaagcac
    19861 tcatcttcta caggaggagc gattaacatt gatatgtcta aatcgaaagg tgctgctatg
    19921 gtgatgtata caaataaaga tactactgat gggccactaa tgattttacg ctctgacaaa
    19981 gatacgttta atcagtcggt tcaatttgtg gattacagag gtaagactaa tgctgtaaat
    20041 attgtaatgc gccagccaag cacacctaat ttttcctcgg cacttaatat aactagtgcc
    20101 aatgaaggcg gtagtgcgat gcagctacga gggtcagaag aagcgctagg aacgctaaaa
    20161 attactcatg agaacccaag tcttaaagcg aattatgata aaaatgcggc agcgttatcc
    20221 attgatattg tcaaaaagac aaacggtgca ggaacagccg ctcagggaat ctacattaac
    20281 tcaacctcag gcacgacagg gaagttgctt aggattagaa accttggtga tgataagttc
    20341 tacgtcgagc atgacggtgg tttttatgcc aagaaaactt cgcagattga tggcaacctg
    20401 aaactcaaga atcccacagc gagtgatcat gcggcaacca aagcttatgt tgatgatgaa
    20461 gtcaaaaaat taaaagcact cttaacgaat aagcaagcgt aaagaggagg agatatgagc
    20521 agagacccaa cactaacatt agacgagtca aaactcgtca taggaccaga tgatcgtatg
    20581 cactacacgt ttactgcaca agatgataac caaaaagtca gactagccag caactgtcta
    20641 gggacagctc actttaatca agtcatgatt gagcgaggga ataagccaac taactacgtg
    20701 gcaccagtgg tagtcgaggg tgacggtaat ccgactggac tatttaaaga cctcaaagag
    20761 cttaatttag agctgacaga tactgccaac tctcagctct gggcaaaaat caagctaaat
    20821 aaccgtggga tgttacagac atactttgat acgactatta aaaatgagat tttaacaacg
    20881 gctcaaggta tcagagagac tatatctgat actgagcgag gtcttaaatc tgagttttta
    20941 aagacggtgc aaggtcagcg tatccggctt gagagcttac tagagcaaaa gaccgctcaa
    21001 ctcggcttga cggtcgatgg tctaagactt gatttaaaca aagcagacaa gcagacagct
    21061 agtttacagg ctagtatcaa tggtttgcga caagaatatc aagacgctga aaggaagtta
    21121 tccgcaagct atcagactgg cattaacggc ctaaaagcaa caatggccaa tgataaatac
    21181 gacctaaaag ctgagataca agcaaccgct cgaggattat cacaagagta tgatgataag
    21241 ttacatcagt tgtctgctaa gattaaaaca acctcatcag gcacgacaga ggcctacgaa
    21301 aacaaactca acagcttgcg tgctgagttt actcgtagta atgaaggcat gcggacagaa
    21361 ctcgagtata aaatcacagg actaagagct gtacaacaga caacagctag tcaaatctca
    21421 caagagatta aaaaccatga aggcgcagtt agtcgtgtgc aacaggattt aaacagctat
    21481 caaagacgtt tgcagaacgc agagggtaat tacaacagtt tgagagagac agtgacaggc
    21541 tatgagcgca ggatatccaa tcaggataac actatctcct ctaactttac tcagctaaag
    21601 accttgatag atcagtctgt gaccttggag aaggtccagt cgctcttgcg gcaatctggt
    21661 gatagtatca tgctcgcgat taaggacaag ttgcctaaga gcaagatgtc tggtaatgag
    21721 ataatctcag cgattaacct aaactcccac ggtgtgcaaa tagctggtaa aaacatcact
    21781 cttgatggca ataccactgt caacggcgct tttaccacaa agattgccaa cgctatcaaa
    21841 atcaaggctg accagattat cgcaggagtg attgacgctg ctaagattag agtgattaat
    21901 ctaaacgcca gcagtatcgc tggcttagac gctaacttta tcaaggcaag aattggctat
    21961 gcaattaccg atttgcttga gggtaaagtg attaaggcac gcaatagcgc tatgcttatc
    22021 gaccttaaca gcgctaagct tgattttaac agtaacgcga ccatcaactt taacaacagc
    22081 aataacgctc tagtacgtaa agatggcaca catactgcct ttgtacattt tagtaatgcg
    22141 acgccaaaag gctatagagg ctcagcgttg tatgcgtcaa tcgggataac ctcatcagga
    22201 gatggcatcg acagcgcttc gtctggacgt tttgcgggta tgcgttgctt taggcaagcg
    22261 tcagggtaca accacactgc aagtgtcgac cagacagaaa tttatggtga taatgtactt
    22321 attgcagatg actttaacat caatagaggc tttaagttta ggccggacaa aatgccaaaa
    22381 atggtcgata tgaacaactt gtatgctgct gttgttgcac ttggacgttg ctggggacat
    22441 ctgaagaatg ttggatggaa taccactcac agcaatttta taaatgctgt taacaatgag
    22501 ttaaataccc acgtcaataa aattaattag gagaaaaaat gcaagaaaaa ttattaggta
    22561 aaatcattaa cgatttaaca ataaaagtcg caaatttaac gctagaaaat gctcaattaa
    22621 aagcacagca tgaaatcgaa ttggaagaac taaacgcaca attggatgaa gcaacagcac
    22681 cgaaggaaga aggtaaataa acatgagaaa ttggaaagtc acaggaaaat acccacaatc
    22741 tgacagtaca ggagcagtcg caagcacata cgttgttatt acagatgatg acggcgctgt
    22801 tatcccacaa ctgattaagc aggacttaac ctcaactaac gatacagaga caatcaaagc
    22861 tgtcttagaa gagtttaaaa aatctgaata cgtcgaaatc gctatgggtg aagccgtgca
    22921 aaaagtggac gatttagaaa aaatctcaca gcaaactgcc aagactgcca aaactgctca
    22981 aacagccgca ggactagcta aagtgtccgc agagcgtacg caaaagatga ttaacttaca
    23041 aacgatccac gttttgacta ctagcgataa agtagagcct gatatttaca aaggcatgtt
    23101 agagctaatc gagcctgtca aaaaaggtga gtatcaagct tatgatgtgt ttacggtagt
    23161 ggacgaaaag cacgaagaca aagctggcga aggtaattta gtctttgtac acgttaatga
    23221 gccgtttact tatgaggcac agacattaga ggagctggag tcagaggaca aagtcacagt
    23281 tatcaaatat gcggacttag ttaaagatta gcgaggtagg ctatggcaac agaattgata
    23341 tttggcgttg gtggctttat tttagctatc gtcacgactt acaatatttt taatgcaaaa
    23401 tccatcaagc atgcgacaga tattacattg ttgcagtctg aggtagagca tttaaaaatt
    23461 gttacacgcc aaaatgctag gcggcttgaa gagcacgctg aacaaaataa aacattgatt
    23521 acaatgacag agcaaattaa aaatttaaca gatgatgtta aagatttaaa agatatgatg
    23581 agaggggaag ttaaatgatc aatttaaaat tacgactaca aaacaaagta accttgatgg
    23641 ctattttggg agctatcttt ttgttagcgc aacaactagg tattaaatta ccatcaaaca
    23701 ttgcggacat tgccaataca gctgtaacgc ttttggtact gcttggcgtt gtcacagacc
    23761 caaccacaaa aggggtgtca gacagtgagc aagcattgac ttaccacgaa ccaaaacaat
    23821 aggaggggac atgcgagcaa tcacacgatt agcattagtt atagcaatcg caatactgta
    23881 tgtgccgttg tctgtggttg ctcttatctt ttatccgttt ttagataagg aggacagatg
    23941 acctttttag ataacattaa gcaaggctgc ttagatggct ggactaagta caaaatcttg
    24001 ccatccttga ccgcagcaca agcaatctta gagagcgggt ggggtaaaca tgccccacat
    24061 aacgctctgt ttgggattaa agctgatgca agctggactg gtaagtcgtt tgatactaag
    24121 acgcaggagg agtaccagcc tggtatcgtc acggatattg tggaccgctt tagggcttac
    24181 aatagttgga atgagtcaat tcttgatcac gggaagtttt taaatgaaaa tccacgatac
    24241 aagtcagtta tcggggagac cgactacaaa aaggcctgtc atgccattaa agatgcaggg
    24301 tatgcgacgg ctagcggcta tgcagagtta cttatccagt tgattgaaga aaatggcttg
    24361 caggaatggg ataaggaaat cttaacaaat caaaaggagg taacgatgac aaccgcaaat
    24421 gagattgtaa aatactgtgt cgaccttgcc aattcaggta tgggagttga caaagacggt
    24481 gcttatggga cgcaatgctg tgacttacca tgttttatcg tcaaaaactg gttcggcatt
    24541 gatttatggg gtaatgcgat tgacctgtta aacagtgcat ctgcgcaagg gctagaggtc
    24601 atatataatg cccctggagt caatccaaaa gctagtgacc tttttgtcat ggaggtagct
    24661 ggcagtcctt atggacacac aggagctgtt attgaggaca gtgatggcta tactattaaa
    24721 accgttgagc aaaatattga cggtaactgg gatagtcttc aggtaggtgg ccccgctcgc
    24781 tttaatactc gtgactttac tggtgttgtc ggctggatta ggttacctgt tgaccatact
    24841 aaccagacag tagatacagc accacaaaac tcggacacaa tcgtagagac accaaaaaca
    24901 ggtacattta cgcttgatgt cgcagagatt aatattagac gttggccaag cctagccagc
    24961 gaagtagtag gtagctacaa acaaggagac actgtcagct ttgacagcga gggttatgcg
    25021 aatggctact actggattag ttatcttggc ggctcgggta tgcgaaacta catggctatt
    25081 gggataactg acaaagacgg taacattatc agtctttggg gtaaattagt gtaaccgaca
    25141 catatgtcgg tagcaaaaaa ggaggtaaag ctccgaaata ataaaccaac cgctctctta
    25201 atagagggcg gttttttgtg ttatgacgga ccttttgatt ttttctatta cgtgagacaa
    25261 aatcgttgta tcctttgtaa taaacgtggc tttttgttga cttatcccta ccctatctgt
    25321 ataatatagt tggacgcagg tgacagatgt attacttgtg ttattttttt atatcaaagg
    25381 aggcaaaaaa tatgataaca gctcttgatg ttgctaatac gtttttagta cgagctaaaa
    25441 acgaaaatat tgatatttct ccaatgaagc tccagaaatt aatctacata ctatataagg
    25501 tatacttaaa agaaactaaa aaaagactat ttgccgaaaa atttgaagta tggaaatatg
    25561 gaccagtcat atctgatgtt tatcaagtat ttaagaaata cagatcaaat aagatttctg
    25621 atttttacaa aaaaaaggac gggtcataca ctactgtgaa actaaataat aatccaaagt
    25681 ttgacaaagt ttttgccgag gtctgggata agtactctcg tgttgatggt atttatctat
    25741 cacaactaac tcatcaaaaa gatactgcat ggtctaaggc tgatgaaaga aacgattatt
    25801 ttttaaatga caatgaaatc tttgaagaaa gtgagtatga aattggagcc tgaaaaagaa
    25861 aatatggaag acatccctat agaagaagat attccaaagc aattgccaac aagctttcaa
    25921 atagataacg agaatcagcc gaaagttagc aaagatatgt ttaataccat aaaaggacat
    25981 cacttattag gatggtgcgt ggggctatta gcgcttgttt atggggtaga aacttttgca
    26041 cacaaagggg atataagttc agttggagaa agctttatag aaattattaa gttacttatt
    26101 ttttctctta caggctatct ttttggcact aattcaaaca ataaagatta acagtactag
    26161 aattagtgct gtttttatat tttttacgaa tatataagta ggaggtgctt tatgctaaca
    26221 tacgacgaat ttaagcaagc tattgatgac ggatatatcg taggcgatac agttaagatc
    26281 gtgcgcaaaa acggacagat ttttgattat gtgttacctg gtgagcctgt aagattgtgg
    26341 gaagttgcga cagaggaaaa agtggaagaa gtgttgatgg aattgtggtg aaaagggtgc
    26401 aaaaaagggg caaaacggat taaaaatgaa actattttaa actttttact ataataatta
    26461 ccttttaaat caacacttga actattgtga accattgtgt acaatagtag tagattccgg
    26521 caggggtcat tattgtcact gaaaaagcct ttacatcaaa ggctttttgt tttattccgg
    26581 ttttaaaagg gtcagtttgt ttatttataa tttctttcat gtttacagtt gtgtgactgt
    26641 aaatagataa tgttgttttt ggatcgctgt gaccaactct atccattatc gcatttagcg
    26701 gtatcccttt ttctgctaaa aatgatatat gcgagtgtct aaataagtgc gtgtgataat
    26761 ctccgtaaat tttcaatcgc ttattgatgt acgcttttaa aattggtaaa ccttttgaat
    26821 atggaaagct gttagcactc tgcttgtgat taatctatcg tatgttaaaa gtgacattta
    26881 aattaaatca ttttttatac atatatttca aaaggattta tcatattgga aaatagcggt
    26941 gcttctattg gcattttact attgacagga atttccctgc cttttgtctc ctaaagaaga
    27001 tcagctttga tttctaactt gattagagtg ggcttggtac tgtttatgaa ttatcagtac
    27061 atactttctg gagatcaaaa aggaaaggaa cagctaaaga ggtgtatgtg ttaccattag
    27121 aggaatagaa catcgcaaga ctcgtttatt cagtcattac gatacctgtt ttatttgtga
    27181 aataactata atattaagtg aatttgtgat ataatgaaag gtatgaatta tcaagattat
    27241 atatgggatt tgggaggtac cttactcgat aattacgagc tttcaaccca agcttttgtc
    27301 caaacgctag cttttttcag ccttccagga gatcacgatg ctgtttacca aaaattaaaa
    27361 gaatcaaccg ctatcgctgt ggcaacgttt gctcctaatg agccagaatt tttgcatgtg
    27421 tataggctaa gagaagcaga caaattggca caacccattt ggtgtttggg agctaaagaa
    27481 attttggaaa agatagcgac ttcaggttcg cgaaattttt taatttctca tcgagattgt
    27541 caggtgaacc aacttttaga gcaagctggg ttgctaatct attttacaga agtcgtgaca
    27601 gcttcaaatg gctttgctcg gaaaccaaat cctgaaagtt tgttttattt aaaagaaaag
    27661 tatgatatta atagtggatt agtaattgga gatcggctaa ttgataaaca agcaggacaa
    27721 gcagcgggtt ttaatacctt gcttgttgac ggtagaaaaa acctattgga gatagtaacg
    27781 tagatgattg aagaaaataa acattttgaa aaaaaaatgc aagaatacga tgccagtcaa
    27841 attcaggttc tagaagggct ggaggctgtc cgcatgcgtc cagggatgta tattggctcg
    27901 acagctaaag agggtttgca tcatttagtc tgggaaattg ttgacaactc aattgacgaa
    27961 gcattagcag gttttgcctc tcatattaaa gtctttattg aagcagataa ttccattaca
    28021 gtagtagatg atggccgtgg aattccagtt gacatccaag ccaagacagg acgtcccgcc
    28081 gttgaaacag tttttacagt cttacacgca ggtggtaaat ttggtggagg cggctataag
    28141 gtttctggag gactacatgg tgtagggtca tctgttgtta atgctttatc aacacaatta
    28201 gatgtgcgtg tttataaaaa tggtcagata cattaccaag aatttaaacg cggggctgtt
    28261 gtagcagatc ttgaggtcat tggaaccact gatgtgactg gcacgaccgt acactttaca
    28321 cccgatccag aaatttttac cgaaacgact cagtttgatt acagtgtttt agcaaaacgt
    28381 attcaagagt tagccttttt gaatcgtggt ttaaaaattt ccattacaga taagcgctca
    28441 ggtatggaac aagaagaaca tttccattat gaaggtggaa ttggttctta tgttgaattt
    28501 ttaaatgata aaaaagatgt tatctttgaa acgcccatct atacagatgg tgaattagaa
    28561 ggtattgcag ttgaagtagc catgcaatac acgactagct atcaagaaac agtcatgagt
    28621 tttgctaata atattcatac tcatgaaggt ggaacgcatg aacaaggctt tagagcggct
    28681 cttactcggg tcatcaatga ctacgctaag aaaaataaaa ttcttaaaga aaatgaggac
    28741 aatttgacag gagaagatgt tcgtgaaggt ttgacggcgg taatttctgt taagcatcca
    28801 aatcctcaat ttgaaggtca aaccaaaaca aaattgggca actcagaagt ggttaagatc
    28861 actaatcgtc tctttagtga ggcctttcaa cgttttcttt tggaaaaccc acaagttgct
    28921 cgtaagattg tggaaaaagg gattttggct tctaaagcta gaattgcagc taagcgagcc
    28981 cgcgaagtca cccgcaaaaa atcaggctta gaaatttcaa acttacctgg aaaattagca
    29041 gactgttcgt caaatgacgc taaccaaaac gaacttttca tcgtcgaagg agattcagcg
    29101 ggtgggtcgg ccaaatcagg tcgtaaccga gagtttcaag ctatcttgcc tattcgcggt
    29161 aaaattttga acgtggaaaa agcaactatg gataagattc ttgccaacga agaaattaga
    29221 agtctcttta ccgctatggg tacaggtttt ggtgcagact ttgacgtgtc aaaagctcgc
    29281 taccaaaagc tggttatcat gaccgatgcc gatgtggatg gcgctcatat tagaacctta
    29341 cttttaacct tgatttaccg ctttatgaga cctgttctag aagctggcta tgtttacatc
    29401 gcccagccac ctatttatgg tgttaaggtc ggtagtgaga ttaaagagta tattcagcca
    29461 ggtattgatc aagaagacca attaaaaaca gctcttgaaa aatatagtat tggtcgttca
    29521 aaaccaactg ttcaacgtta taaaggtctt ggggaaatgg atgaccatca actttgggaa
    29581 actactatgg atcctgaaaa tcgtttgatg gcgcgtgtga cagttgatga tgccgcagaa
    29641 gcagataaag tatttgatat gttaatggga gatcgtgttg aaccaagacg tgatttcatt
    29701 gaggaaaatg cggtttatag tacactggat atttagtcac ctttttagtt tcacaaggaa
    29761 tctgctacca aagaggacga attgactaaa aatcatgatg catgatgcca acagctttgt
    29821 tagttagtac gtcttcatct tgagggacag cgttaatgca taggtattga gaccgcccct
    29881 taatacctat gttagtcctt attaagaaag ccttgtgagt cgctggtacg agattgttga
    29941 attagtcaaa tatattttga aatgcatttt aaagtatgtt ataatcgtaa tgttatagtg
    30001 tattttaaat aaaattttaa taaaaggcga ttgaggaatt tcagttttta gttattactg
    30061 gaacaatgtt gataaatcgt gtctaaataa taaggagatt cagatgtcaa gcggaattat
    30121 cttgctgatt gtggctatag tcctactagt gattatcgcc tatctagtgg gtgtcatcat
    30181 acgaaagcgt aatgattccc taattaccag tctagaagaa cgaaaacagg ccttgtttgc
    30241 tttgcctgtt aatgatgaaa ttgaagaagt aaagtcactt catttgatag gacagagcca
    30301 aacctctttt cgggaatgga atcagaaatg ggtagactta actgtaaatt cgtttgcaga
    30361 tattgaaaat catatttttg aagctgaaaa tttgaatgat acgtttaatt ttattcgcgc
    30421 caagcatgag attaatagcg ttgaaagtca gcttaatctt gttgaagaag atatcgcttc
    30481 tattcgtgag gcacttaata tcttaaaaga gcaagaagaa aaaaatagtg ctcgtgtcac
    30541 ccatgctctt gatttatatg aaaagctcca agcttctatt tctgagaatg aagataattt
    30601 tggttcaact atgcctgaaa ttgacaaaca gatgaaaaac attgaaactg aattttcaca
    30661 gtttgtcgca ctcaactcat caggtgatcc tgtagaagct tctgaagttc tggatagagc
    30721 agaagagcat actattgctc tagggcagat tacagagcag attccagcta ttgtcgccaa
    30781 gttggaagat gattttccag atcagttaga tgatttggaa acaggatatc gccgtttact
    30841 tgaagaaaac tatcattttc cagaaaaaaa cattgaggca cgttttcagg agattcgtga
    30901 gtctattcgt gccaattcat cagagttagt tacacttgac ttggatcgtg ctagagaaga
    30961 aaacacgcat attcaagaac gcattgattc tctttatgaa gtctttgagc gcgaaattgc
    31021 cgcttataag gtagctgcta aaaatagtaa gatgctacct cgttacctag cacatgtgaa
    31081 acgtaataat gaacaactca aagatgaaat tgcacgttta tcacgtaaat atattctaag
    31141 tgaaacggaa agtctgactg ttaaggcatt tgagaaggat attaaagaga tcgaagacag
    31201 tacacttgct gttgcagaac aatttggttt acaagaaaaa ccattttcag aactgcaagt
    31261 gacttttgaa cgcagtataa agacgcttac taatgtcgag tcaggtcaaa tggatgtttt
    31321 tgcagcagtt aaagatattg aaaaaattga atcacaggca cgccataacc ttgatgttta
    31381 tgttactcag cttcatatga ttaaacgtta tatggaaaaa cgtcacttgc ctggaattcc
    31441 acaagacttt cttagtgctt tctttacaac gagttcacaa ttggaagctt tgatggatga
    31501 gcttagtaga ggacggatca atattgaggc agtgtcacgt ttgtcggaag ttgcgacggt
    31561 tgctattgct aatctagaag atttaaccta tcaagtggtt caaaatgcta ccttgactga
    31621 acaattacta caatattcta atcgctatcg ttcttttgaa gcaggagttc aaagtagttt
    31681 tgaacatgct ttgagacttt tcgaagtaga aaatgattat caggcttctt ttgatgaaat
    31741 ttcttatgct cttgaaacag ttgaacctgg ggtaacagat cggtttgtta actcttatga
    31801 aaaaacacga gagcacattc gtttttgata cttgaaagtc gtgatattct cacgactttt
    31861 tattagcttt ttggaccaat acgtgtttct gactagaatc ttctttttaa tgatcaaacg
    31921 aagaagtagt aacagtgttt tttgctattg agaggatagt tattttttca aaaatctttt
    31981 ccaaaaggat ttggtttttt caggagtttg tttgctaagt tgatcgtttt ttgtctgctt
    32041 taagatgact tctaaacgcg tttcctttag atttattgcg tggtcggtat gaaggataaa
    32101 cgcaaaaggt gaagtcatat gtgtttctgt aataatagta acaggtaaat ggttttcttt
    32161 tgctaatttc atatagagta tttgaagttg aggtgccagc ttggaagaga tttttaagtg
    32221 taaaggttga tagactaact gaaggctcgg taattctctt ttcaaatagt cttttactgt
    32281 tttagtttga gcttcgttta ataaagcact taaaacgact cgttcagcat acgttcctag
    32341 atagtagcgt tgctgctcag gatttaatct tctttctccc caggctcctt ttaatagctt
    32401 atcttctaaa ttagtcatag ataccctcgc ttctttataa tagtttcttt attatatcga
    32461 tttctacaat aaaataccaa tttgaaaatt ttcggtaaat gtgttaaaaa acaagaaaga
    32521 aagtgatttt tcttgcaaaa aacaaaggaa gcttttcatg agattgcttt ttaagttgat
    32581 taaaggccta gtttgtggta ttatgaacat gtaaaatatt aaaactcata aggagagtat
    32641 tacaatgtca attattactg atgtatacgc tcgcgaagtc cttgactcac gcggtaaccc
    32701 aacacttgaa gtagaagttt acacagaatc aggtgcattc ggacgtggta tggttccttc
    32761 aggagcttca actggtgaac atgaagccgt tgaacttcgt gatggtgaca aatctcgtta
    32821 ccttggtctt ggtactcaaa aagctgttga taacgttaac aacattatcg ctgaagcaat
    32881 catcggttac gatgttcgcg atcaacaagc tatcgaccgt gcaatgatcg cacttgacgg
    32941 tactcctaac aaaggtaaac ttggtgctaa cgctattctt ggtgtttcta tcgctgttgc
    33001 tcgtgctgct gctgactacc ttgaagtacc actttacact taccttggtg gattcaacac
    33061 taaagttctt ccaactccta tgatgaacat catcaacggt ggatcacact cagatgctcc
    33121 aattgcattc caagagttca tgatcatgcc agttggtgca cctactttca aagaaggtct
    33181 tcgttggggt gctgaagttt tccacgctct taagaaaatc cttaaagaac gcggacttgt
    33241 tacagctgta ggtgacgaag gtggatttgc tcctaaattt gaaggaactg aagacggtgt
    33301 agaaactatc cttaaagcta ttgaagcagc tggttacgaa gctggtgaaa acggcattat
    33361 gatcggtttc gactgtgcat catcagaatt ctacgacaaa gagcgtggcg tttacgacta
    33421 cactaaattt gaaggtgaag gcgctgctgt tcgtacatct gcagaacaaa tcgactacct
    33481 tgaagagttg gttaacaaat acccaattat tactatcgaa gatggtatgg acgaaaacga
    33541 ctgggatggt tggaaagctc ttactgaacg cctaggcgga cgtgttcaat tggttggtga
    33601 cgacttcttc gttacaaata ctgaatacct tgctcgtggt atcaaagaaa atgcagctaa
    33661 ctcaatcctt atcaaagtta accaaatcgg tactttgact gaaacttttg aagctatcga
    33721 aatggctaaa gaagctggtt acactgccgt tgtatcacac cgttcaggtg aaactgaaga
    33781 ttcaacaatc gctgacatcg cagttgcaac aaacgctggc caaatcaaaa caggttcatt
    33841 gtcacgtaca gaccgtattg ctaaatacaa ccaattgctt cgtatcgaag atcaacttgg
    33901 tgaagttgct caatacaaag gaatcaaatc attctataac ttaaaaaaat agacggtaag
    33961 acagaaatcg gtcattcgta gaatgcgatt tcgtcgtcgc acctccgtca ggctgactag
    34021 gttggtcacg acaaaaggag tgaacatcca gtcagctacg acgcaaaagt taaagattaa
    34081 agaatagaaa gcttgggaaa atcccaagct ttttgatttc taaatagtga aaatttactg
    34141 tggactaatt tatcctgagc taatgtatta gcgaggtaaa gttattgagg aaggcttgga
    34201 tttgtactgc ctctaaaaag ttggagacta tattttaaat acaggactaa gtccttttat
    34261 accaattgtc aagcacatca aggttttaac tgaaaaaatg ttttagacaa tagcctaggt
    34321 ttagctgttg tcttacttgt tgtgctctga ttagcataaa aaagtgtaca agaaaaaacc
    34381 ttgcctagaa tttttaagat caaggtgtta caatgataga gcaacaacga ctttaatgat
    34441 tttgggtcga agcgtaattg taaagtttgt tatgcgttat gaggtaaagc attgtcctga
    34501 caaggcaatg tctagaggca atcgtatgtg gcttggttga agctgtttgc gattgccttt
    34561 ttcgtttctc atagaagtct gcgatatgac aaggattggt atgactagca gaagcaatgt
    34621 catggataca cttgaaaaga atctttggag cataaggatt cctacgtttg gtaatgtgct
    34681 cttgagctag atagttgcca gactcataat gtctaaagtc aatcccaatg aaagcattaa
    34741 tttgattagc agattgaaaa cgacgaatag caccgagttc gccaataata cttgttgcag
    34801 ttgtttctgc gatacttgga atagagcgta gaatcttgtc ttctggtaaa ggttgagcca
    34861 acgccaccat cttatcaaaa atagcttgac gacgttcaga aagtctaagt aattctttgg
    34921 catagtagcg aacctcttct atcatcggag aggttttcgt aacagtaaaa taagactgct
    34981 tggctaatga gacaagtttt tccactaagt agatcccacg cttgtcagag atacgtttag
    35041 aggtagattg acggatgata gctgacaatg ctttgtcagc tagctccagt acaaagctat
    35101 tacatggaaa agccgttacc acattccagt attactcacc agttggtgca aataagatgt
    35161 gttccagttc aggaaaagtg acttgtaaga tcttgtgaag gcgattctta actctcgaac
    35221 aatattatcc tcagtcaatt tttgatagaa gcgactcaag tcacgtagca gctgataaac
    35281 ttcttcctga acgtaagttg gttttctaac tagaataaat tgagactgag ccaatttttc
    35341 agtgtctaac ttatccgctt tacgcacccg tagactatct agttttctaa aggattgagt
    35401 tgtgtataag cgtagccatt tttctcaagg aaggactgaa gccgacgaga atagactcct
    35461 gttgtgatgg tctccctttt gccttttaaa caatagtata gccgtttttc aagatgttat
    35521 taatgatttt ttcctttatt ctagaagaat aagtctgata ctgtttcttc ttaataatct
    35581 caatgcccta acagtccatc agtcgaacgg tatttctcaa attactgcag ttgactcttg
    35641 cgttcagttc cctcaccttg tggatgccgt ttagaacaat attagcttgc tgagcctttt
    35701 ggtaatgtga acaaagcatc tttatcactc aaggagaaga caggttcttg tggtaagtgt
    35761 ccaacaaggt cacgataaac tcatcgtacc gtttttggcg gaagtctaga aatgccttag
    35821 aatgtaagcc tcagaaacgt ctctaaaact aaacaagaaa tacaagaaca aatgcccttg
    35881 attctggtac aaatgctgta tcaggttcag atattgccta tctgcgataa tgacactctg
    35941 cttttcctta acaatatctt tgaaaggaat gatttcgaca ttgacaggca taaccgttgc
    36001 aatagctggc gggaagtaaa tcgagagtgc attggtcatc aaatccagcg cagcagtgtt
    36061 attggtcaaa agatagacag gtatcggtgg caaatatgtt tttaggagtt cctctaactg
    36121 tatcgtgaag agcagtaaat gataggacgg cagtttcccc acgatgcctt ctgcgctcat
    36181 ccattcctca acgatggttt ttagagtatt gtagaagctc ttgtttcgtt tttgctgtct
    36241 tctgaggtaa tggaacaagt gtatgtcagg taacaaaact tgaagattac tgataaagag
    36301 acgtgagaag gaaaccaaaa tccgtttgaa aggaagggag tttaggatat tattgcctag
    36361 tagtggacgc agggatgctt tcaaggtttt tccaattgtt tttgtcatca ccaactcaaa
    36421 caattctttc acttttttag gtgtccattt atccttatgg aaaggattat tggtggtgca
    36481 aaaacataag aaaatataat ccaaatcctc atcagttaaa tcaggatggt accattttcc
    36541 gatgatttcc tgactggtca ttttgatatc gtgatagata gacagttttt tcaagtgttt
    36601 gaatgcatct gtctgaggga tccccaagtt atcatgtcgc cgtttccata taagggatat
    36661 cagaatggca aagtacgaaa attcataagg ggctttactg gcatcattaa gtgtgatggc
    36721 ttgattggag tttataatca gcgaaaccac tttattcatt gatgttttat caaaatcata
    36781 aatggtcata ccaaactgat agtgcaacaa ggcgatcaga aagcggatac ggtattctgg
    36841 tccaacaaca tggttttgcc gaacgtttaa acctaccttt ttcaagtatt tccgacaatt
    36901 ggtcctgata cggtaagcgg tggcttggga aatatactct cgtttaatga agtcgtgtag
    36961 gctcagctct cctggttcaa ttaaaaaaca taacatcttt aagaatatcg aggtttgata
    37021 gagtttctta aaataaggca ttttaagttg gtaggtctta taggggatag aaacagtgtc
    37081 gtcacaaatg gttaaggtga gggtgtcttc taaatcctta atcatttcaa tgagtaagtt
    37141 gtagacacgt tgttttttga gttcggtttc ctgacacaac tggtctatgg agacttcgga
    37201 aacgtctaac aaaatgttga gcagtgataa tttatcttgt agtttggttt ctagatgaag
    37261 gtgtaacata actgaactcc tttcattttt atagcagaaa ctcgtattta tttaattatc
    37321 acataattaa ataaaacagt
//
LOCUS       DAUNLR010000014        36796 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUNLR010000014 DAUNLR010000000
VERSION     DAUNLR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36796
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.014"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            128..1120
                     /gene="manX"
                     /locus_tag="VLL59_000681"
     CDS             128..1120
                     /gene="manX"
                     /locus_tag="VLL59_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HER6508824.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            1209..2018
                     /locus_tag="VLL59_000682"
     CDS             1209..2018
                     /locus_tag="VLL59_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HER6508825.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            2035..2946
                     /locus_tag="VLL59_000683"
     CDS             2035..2946
                     /locus_tag="VLL59_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HER6508826.1"
                     /translation="MTEQIKLIKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSITFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            3060..3419
                     /locus_tag="VLL59_000684"
     CDS             3060..3419
                     /locus_tag="VLL59_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HER6508827.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            3811..5088
                     /gene="serS"
                     /locus_tag="VLL59_000685"
     CDS             3811..5088
                     /gene="serS"
                     /locus_tag="VLL59_000685"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HER6508828.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRVFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPGESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(5310..6080)
                     /locus_tag="VLL59_000686"
     CDS             complement(5310..6080)
                     /locus_tag="VLL59_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HER6508829.1"
                     /translation="MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(6077..6943)
                     /locus_tag="VLL59_000687"
     CDS             complement(6077..6943)
                     /locus_tag="VLL59_000687"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HER6508830.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKEQKIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            complement(6952..8316)
                     /locus_tag="VLL59_000688"
     CDS             complement(6952..8316)
                     /locus_tag="VLL59_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HER6508831.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            complement(8348..8770)
                     /gene="fabZ"
                     /locus_tag="VLL59_000689"
     CDS             complement(8348..8770)
                     /gene="fabZ"
                     /locus_tag="VLL59_000689"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HER6508832.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            complement(8767..9267)
                     /locus_tag="VLL59_000690"
     CDS             complement(8767..9267)
                     /locus_tag="VLL59_000690"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HER6508833.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAIGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            complement(9269..10501)
                     /gene="fabF"
                     /locus_tag="VLL59_000691"
     CDS             complement(9269..10501)
                     /gene="fabF"
                     /locus_tag="VLL59_000691"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HER6508834.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            complement(10516..11250)
                     /gene="fabG"
                     /locus_tag="VLL59_000692"
     CDS             complement(10516..11250)
                     /gene="fabG"
                     /locus_tag="VLL59_000692"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HER6508835.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPIKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            complement(11240..12178)
                     /gene="fabD"
                     /locus_tag="VLL59_000693"
     CDS             complement(11240..12178)
                     /gene="fabD"
                     /locus_tag="VLL59_000693"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HER6508836.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKTPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            complement(12203..13174)
                     /gene="fabK"
                     /locus_tag="VLL59_000694"
     CDS             complement(12203..13174)
                     /gene="fabK"
                     /locus_tag="VLL59_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HER6508837.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQVGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            complement(13375..13599)
                     /locus_tag="VLL59_000695"
     CDS             complement(13375..13599)
                     /locus_tag="VLL59_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HER6508838.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            complement(13660..14634)
                     /locus_tag="VLL59_000696"
     CDS             complement(13660..14634)
                     /locus_tag="VLL59_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HER6508839.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDETTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            complement(14635..15069)
                     /locus_tag="VLL59_000697"
     CDS             complement(14635..15069)
                     /locus_tag="VLL59_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HER6508840.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            complement(15146..15937)
                     /locus_tag="VLL59_000698"
     CDS             complement(15146..15937)
                     /locus_tag="VLL59_000698"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HER6508841.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            complement(16157..17293)
                     /gene="dnaJ"
                     /locus_tag="VLL59_000699"
     CDS             complement(16157..17293)
                     /gene="dnaJ"
                     /locus_tag="VLL59_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HER6508842.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(17574..19400)
                     /gene="dnaK"
                     /locus_tag="VLL59_000700"
     CDS             complement(17574..19400)
                     /gene="dnaK"
                     /locus_tag="VLL59_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HER6508843.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVTEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(19581..20153)
                     /gene="grpE"
                     /locus_tag="VLL59_000701"
     CDS             complement(19581..20153)
                     /gene="grpE"
                     /locus_tag="VLL59_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HER6508844.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(20156..21190)
                     /gene="hrcA"
                     /locus_tag="VLL59_000702"
     CDS             complement(20156..21190)
                     /gene="hrcA"
                     /locus_tag="VLL59_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HER6508845.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(21325..21894)
                     /locus_tag="VLL59_000703"
     CDS             complement(21325..21894)
                     /locus_tag="VLL59_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HER6508846.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(21891..22634)
                     /locus_tag="VLL59_000704"
     CDS             complement(21891..22634)
                     /locus_tag="VLL59_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HER6508847.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAARAIDSQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGT
                     SEHHTGLAIDMSTVDTLNASDPSVSKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            complement(22624..23331)
                     /locus_tag="VLL59_000705"
     CDS             complement(22624..23331)
                     /locus_tag="VLL59_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HER6508848.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            complement(23723..23962)
                     /locus_tag="VLL59_000706"
     CDS             complement(23723..23962)
                     /locus_tag="VLL59_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HER6508849.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(24181..24396)
                     /locus_tag="VLL59_000707"
     CDS             complement(24181..24396)
                     /locus_tag="VLL59_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508850.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTAYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNHHVCPHYY"
     gene            complement(24393..25832)
                     /gene="gatB"
                     /locus_tag="VLL59_000708"
     CDS             complement(24393..25832)
                     /gene="gatB"
                     /locus_tag="VLL59_000708"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HER6508851.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGAIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            complement(25832..27298)
                     /gene="gatA"
                     /locus_tag="VLL59_000709"
     CDS             complement(25832..27298)
                     /gene="gatA"
                     /locus_tag="VLL59_000709"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HER6508852.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYTEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(27298..27600)
                     /gene="gatC"
                     /locus_tag="VLL59_000710"
     CDS             complement(27298..27600)
                     /gene="gatC"
                     /locus_tag="VLL59_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HER6508853.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(27832..28167)
                     /locus_tag="VLL59_000711"
     CDS             complement(27832..28167)
                     /locus_tag="VLL59_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
                     /protein_id="HER6508854.1"
                     /translation="MKDRYFFCDVVGKCLEEYVDRGIFDKEPFQTFDQKGIGRLFSTA
                     VSLARSVKPDLKLGICGEHGGDPASIAFCHSQGLTYVSCSPFRVPLTRLAAAQAAIKA
                     SGHSLTQDK"
     gene            complement(28613..29167)
                     /locus_tag="VLL59_000712"
     CDS             complement(28613..29167)
                     /locus_tag="VLL59_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HER6508855.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(29314..30096)
                     /gene="codY"
                     /locus_tag="VLL59_000713"
     CDS             complement(29314..30096)
                     /gene="codY"
                     /locus_tag="VLL59_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HER6508856.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PIESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(30314..31528)
                     /locus_tag="VLL59_000714"
     CDS             complement(30314..31528)
                     /locus_tag="VLL59_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HER6508857.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            31759..32211
                     /locus_tag="VLL59_000715"
     CDS             31759..32211
                     /locus_tag="VLL59_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HER6508858.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(32334..33722)
                     /locus_tag="VLL59_000716"
     CDS             complement(32334..33722)
                     /locus_tag="VLL59_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HER6508859.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDVEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQASNKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            33794..34759
                     /locus_tag="VLL59_000717"
     CDS             33794..34759
                     /locus_tag="VLL59_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HER6508860.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(35108..35812)
                     /locus_tag="VLL59_000718"
     CDS             complement(35108..35812)
                     /locus_tag="VLL59_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508861.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(35825..36727)
                     /locus_tag="VLL59_000719"
     CDS             complement(35825..36727)
                     /locus_tag="VLL59_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6508862.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
BASE COUNT        10987 a         7980 c         6481 g        11348 t
ORIGIN      
        1 aaacgtttta aaatagaaac gttcttgaat ttcgtttaag tgaaaaagaa ttgccaaaat
       61 ttagttttgg aaagagatta ttcttcttca tttcaacgaa aaatatttta aaggaggaag
      121 aacaagaatg ggtatcggta ttattattgc cagccatggt aaatttgctg aaggtattca
      181 tcaatctggt tctatgattt ttggtgaaca agagaaagtt caagttgtta ctttcatgcc
      241 aaacgaagga ccagatgatt tgtatggaca cttcaacaat gctatccaac aatttgatgc
      301 tgatgatgaa atccttgtgc tagctgacct ttggagtggt tctccattta accaagctag
      361 tcgtgtggca ggtgaaaatc ctgaccgcaa aatggcgatc atcactggtc tcaacttgcc
      421 tatgcttatt caagcttaca ctgaacgtct tatggatgct ggtgcaggtg ttgaacaagt
      481 tgctgcaaac atcattaagg aatctaagga cggtatcaaa gcccttcctg aagaccttaa
      541 cccagttgaa gaaactgctg caactgaaaa agttgttaac gcacttcaag gagctattcc
      601 tgctggaact gtcatcggag atggtaaatt aaagatcaat cttgctcgtg ttgacactcg
      661 tcttttacac ggtcaagttg caacagcatg gactccagct tctaaggctg accgtatcat
      721 tgttgcttct gatgaggttg ctcaagatga tcttcgcaaa caattgatca aacaggctgc
      781 acctggtggt gtcaaagcta acgttgttcc aattagcaaa ttgattgaag cttctaaaga
      841 tcctcgtttt ggtaacacac acgcacttat tcttttccaa acccctcaag atgcccttcg
      901 cgcggttgaa ggtggtgttg aaatcaacga attgaacgtt ggttcaatgg ctcactcaac
      961 tggtaaaaca atggttaaca acgttttatc aatggacaaa gaagacgttg ctacttttga
     1021 aaaattacgc gacctaggtg ttacattcga cgtccgtaaa gttcctaacg attctaagaa
     1081 aaacttattt gagcttatcc aaaaagctaa cattaaataa gtttcaaacg ctataaggtt
     1141 ttaaaacgat gactagctaa cttattagca aaaagtcctc gtttactata ctttgaaagg
     1201 attacaacat gtcagatatt tcgattattt ctgcaatttt ggtcgttatc attgccttct
     1261 tcgctggtct tgaaggtatc ctcgaccaat ttcaaatgca ccaaccactt gttgcctgta
     1321 ctttgattgg acttgtaact ggacaccttg aagctggtgt catccttggt ggtacacttc
     1381 aaatgcttgc tcttggttgg gcaaacatcg gtgctgccgt tgcccctgat gctgcccttg
     1441 cctctgttgc agctgctatc atcatggtca aaagtggcga ctttactcaa aaaggaatta
     1501 cctttgctta ctcaacagct atcccacttg ctgttgctgg tcttttcctt acaatgatcg
     1561 ttcgtacttt gtcaactgcc cttgtacacg ctggtgacaa agctgccgct gaaggtaatt
     1621 tcgcaggtat tgaacgcttc cactttattg cccttcttct tcaaggattg cgtatcgctg
     1681 tcccagcagc tcttcttgtt gctgttccta cttcagccgt acaatctgtt ttgaatgcta
     1741 tgccaaactg gttgaacgaa ggtatgcaaa tcggtggtgc gatggttgtt gctgtaggtt
     1801 atgctatggt tatcaacatg atggctactc gtgaagtatg gccattcttc gccctaggtt
     1861 ttgctcttgc agctatcagc caattaaccc ttatcgctat gggtgttatc ggtgtagcaa
     1921 ttgccttcat ctaccttaat ctttctaaaa aaggtggtaa cggtggtaat gcagcaggtt
     1981 cagctgatcc aatcggcgac atcttagaag actactagaa aggggtaaga acaaatgact
     2041 gaacaaatta aattaattaa atcagaccgt caacgtgttt ggtggcgttc acaattctta
     2101 caaggttctt ggaactacga acgtatgcaa aacatgggct gggcttatgc acttatccct
     2161 gctcttaaaa aattgtatac gtctcctgaa gaccgtgcag ctgctcttga gcgccacatg
     2221 gaattcttta acactcaccc atacgttgca gctccaatca ttggtgtaac acttgccctt
     2281 gaagaagaac gcgcaaatgg tacgccaatt gatgacaagg ctatccaagg ggttaaaatt
     2341 ggtatgatgg gacctcttgc tggtatcggt gatccagtat tctggtttac agtacgccct
     2401 atccttgggg cacttggtgc ttctttggct tcaacaggta acatcgttgg tccacttctg
     2461 ttcttctttg gatggaacct tatccgtatg gccttcttat ggtatactca agaatttggt
     2521 tacaaagctg gttctgaaat tactaaagac atgtcaggcg gtatcctcca agacattact
     2581 aaaggtgctt caatccttgg aatgtttatc cttgcagtgc ttgttcaacg ttgggtatct
     2641 atcaccttta ctatcgacct tcctggaaaa caattgtcag atggtgccta tgtggtcttc
     2701 ccagatggcg ctgttaaagg tgctgagttg aaaactatcc ttgccaacgc tattggtggt
     2761 atgagccttg ataaagtcca agctcaaacc cttcaaggac aattggactc tcttatccca
     2821 ggtttagctg gattactcct tacattcctt tgcatgtggt tattgaagaa aaaagtttct
     2881 ccaatcgcaa tcatcatcgg cttgtttgca tttggtatcc ttgctcacct tgcaggtatt
     2941 atgtaatcaa ccaatggaag tctgagatga actcaggctt cttttttatg ctttatgtca
     3001 ggaaaatccc acttaaaata tggtataata actacaacta cgcaatgaaa ggaactaaaa
     3061 tggctcaatc tttaaacact agtgtcgaat acaagacaaa agctgtctcc taccttggaa
     3121 tgggaggcaa agttggtcat attttactcg gtgacaaggc ccttgaattt tacaacgata
     3181 aaaatgtgaa tgattatatt caaattcctt ggacagctat caatcacatc ggggctaatg
     3241 tttcaagaaa aaaagttagc cgccactttg aaatttttac ggaccaaggc aagtttttat
     3301 ttgcttctgg agactctgga aaaatcttaa aaatcactcg tcaacatatt ggtaatgaga
     3361 aagtgattac attaccaacc ttgatgcaaa cctttattaa caaatttttt cgacattaaa
     3421 aaaataatgc gcagtgccga tttatcattt caagaaaaca aagaatagta gctctaaatt
     3481 gctatttagt ggaaaagatt ccctcatttg agtttacttt ttcttgtttt ttgttataat
     3541 agtcctaacg gataagtaat accttttttt cattcagaga gtctgtggat gctgtgaaca
     3601 gatagggaaa atgatatgaa attctaccgt gtcatcaata aaatagagat taagtgcaca
     3661 gattgtgaag ctggatggaa ccgcgccaaa gcgctccagc atcttcataa gctgtgcttt
     3721 ttctatcgtc agagaatcac aagatccaac tgtcttactt agccttgttt cactgacagc
     3781 tactaataac tatcttaaag gagcttctgt atgctagatc ttaaacgtat ccgtactgat
     3841 tttgacactg tcgctgccaa attaaaaaac cgtggtgttt ctgaagacac cctgacccat
     3901 cttaaagaac ttgatgaaaa acgtcgtact ctattagtgc aatcagaaga attaaaagca
     3961 gagcgtaata ttgcttctgc tgccatcgct caagccaaac gtcaaaaaga agatgccact
     4021 caacaaattg ctgatatgca aaaagtctct gcagatatca aaactattga caatcaacta
     4081 gtagctatcg accagcaagt tactgacatc atcactgttt tacctaatac tcctcacgat
     4141 tctgtccctg ttggagctga cgaagaagac aatgtcgaaa ttcgccgttg gggaacgcct
     4201 cgtgtctttg acttcgaagt taaggctcat tgggatctag gcgaagatct tgatatttta
     4261 gactgggaac gtggggcaaa ggtaactggt gctcgtttct tattctataa aaatcttggt
     4321 gctcgtttgg agcgtgctct ttataacttc atgctggatg aacatatcaa agaaggttat
     4381 caagaaatca tcacacctta catggttaac cacgattcca tgtttggtac aggacaatat
     4441 ccaaaattca aagaggacac ctttgaatta gctgatacca actttgtcct gattccaact
     4501 gctgaagtgc ctttgaccaa ttattaccgt ggggaaatcc tagacggcaa agaattgcca
     4561 atttacttta ctgcaatgag cccatctttt cgttctgaag cgggttctgc gggtcgtgac
     4621 acacgtggcc ttatccgcct acaccaattc cacaaagttg aaatggttaa atttgctaaa
     4681 ccaggagaat cttaccaaga actagaaaaa atgactgcta atgctgaaaa tattcttcaa
     4741 aaacttggtt tgccatatcg cgtcatttcc ctttgtactg gagacatggg cttctcagct
     4801 gctaaaacct atgaccttga agtctggatt cctgcacaaa atacctatcg tgaaatttca
     4861 tcatgttcaa atacagaaga tttccaagca cgtcgtgctc aaatccgtta ccgtgatgag
     4921 gctgacggta aggtcaaact tctccacacc cttaatgggt caggacttgc tgtcggtcgt
     4981 accgtagcag ccattttaga aaactaccaa aatgaagatg gttctgttac catccctgaa
     5041 gtactccgcc cttacatggg tggcgaaacc gtcatttcac ctaaataata aattcacccc
     5101 agagatcatt aaagtgattt ctggggttta ctattttaaa gagccaccac atcacttgaa
     5161 actcactaca ttgccccttt aacaacactt ttcttcacac tagtttatca aaagtcttat
     5221 tagtataccc atttccttat ttacaagact agttaaaaac ccttttggaa aggcctccct
     5281 tcacgtaggg agactccaaa aggatgttgt taatatttac gaaagcgttg gtagcgctca
     5341 tctaataatt ggtctaatgg cttagcttgc aaactggtta tttgttcgat gaggttagct
     5401 ttgatgatgt caacgatttc acttgaaaaa taaccatgtt ctggaataat acggtctact
     5461 atgcccattt gatacaattc gcctgcggta attttcatca attcagcggc ctcggtcgcc
     5521 cttgaaccat ccttccataa aatagaagca aagccttctg ggctaagaac cgcatacata
     5581 gtattttcaa gcatccagac ctgatcggca accgctaagg ctaatgcacc accagagcct
     5641 ccttcaccaa taatgatggc gataatggga accttgagat cactcatttc catcaaattt
     5701 ttagcaatgg cctcaccctg tcctcgttct tccgcaccga cacctggata ggctcctgca
     5761 gtattgataa acgtaacaac tggtcgtcca aatttttctg cctgtttcat aaggcgcaaa
     5821 gctttacgat aaccttctgg attgggctgg ccaaaattcc ttgccaaatt atcctgtaaa
     5881 ttcttacctt tttgaatacc aatgaccgta acaggttgtc ccgccaaata agctaggcca
     5941 cctacaatgg caccatcatc tgaaaaatgg cgatcgccat gcagttccat aaagtcatcg
     6001 aaaataaggt tggcgtaatc caaagttgtt aaacgccctt gatcacgcgc ttcttttaaa
     6061 attcttgata catctgtcat tggccacctc catgaaatgc tactaagtgg gcaatcttgt
     6121 ctcgcaactc tgttcgtttc acaatagcat ccacaaaacc atggtcttgt aaaaattctg
     6181 ctttttggaa atcatctggc aagttttcac gaactgtggt ctcaatgaca cgacgacctg
     6241 caaagccaac caaggattga ggttctgcca aaataatgtc cccttccatg gcaaaactag
     6301 ctgttacccc accagtagtt ggatctgtca aaatagtgag gtaaaagagg cctgcattag
     6361 aatgtctttt cacagctgca gagaccttgg ccatttgcat gaggctcatg atcccctctt
     6421 gcatacgggc gcctcctgaa gccgtaaaaa tcaccaccgg caggttttct tcgatagcca
     6481 attcaaacaa tcgggtaatt ttttccccaa caacagttcc catactagcc ataataaagt
     6541 gagaatccat aatggctaga gcaatctttt gctccttaac catagctttc cctgtcaaaa
     6601 cagcttcatg cagaccagtt gtttccttgg ctttttgtaa tttttcctga taacctggaa
     6661 aacgtaacgg atccttggtt tcaatacttg taaataattc ctggaaagag ccttcgtcaa
     6721 ctgttaaggt cagccgctct tgggcagaaa tcctaaaatt gtaagaacag gttgggcaaa
     6781 tctttgccaa tcccaaatct ttcttataaa tcatgtgctt acaagctggg catttcgcaa
     6841 agagttcatc tggaacttct gggacattat ggctgacaga tcctttgagg gaattattgg
     6901 gagtaatacg gatgtattta tcttttttac gaaataaagc catattttct cctaatcttt
     6961 attgtaatgt ggcaggaacg tttccatcaa gaaagaggta tcataatctc ctgcaatcac
     7021 tcgcttatct gaaatcaaat cgagctggaa gtctgtattg gtgataatgc cttcaatttc
     7081 caattcaact aaggcacgtt gcattttcat caaagcgtca aatcgattgc ttccatgaac
     7141 gatgatttta gcaatcatgc tgtcataata aggaggaatg gcatagccat tgtaaactgc
     7201 tgaatcaact cgtagtccta caccaccact tggcatatac aagtctgtaa tctttcctgg
     7261 actcggtgca aagttaaaag cagtattttc agcattgata cgacattcaa tagcatgtcc
     7321 cgtgatagtg atgtcttctt gattaatcgc caaaggctga cctgctgcaa ttttgatttg
     7381 ctctttgaca atatccactc ctgtcacaaa ttcggtgaca ggatgctcaa cttggatacg
     7441 ggtattcatt tccatgaaat agaatttctc gctgtcttcg tccaacaaaa actcaatggt
     7501 tcccgcattt tcataggcta cagcttcagc tgctctaacc gctgcttgcc ccatttcgtg
     7561 tctgagggta ttgccaatag caatggatgg actttcttcc aagacttttt gattattccg
     7621 ttgcaaggag caatcccgtt ctcccaagtg aatgatgtta ccgtaagcgt ctcctaaaat
     7681 ttgcacctca atatgtctag ctggataaat tactttttcc aaatacatgg cgccatttcc
     7741 gaaagctccc aaagcttctt gactggcagc attgaaagcc gcctccaaat ctgcttctgt
     7801 ctccacttta cgaatccctt tacctccacc acctgccgat gcttttagca tgacaggata
     7861 accaatctta ttggcaatag ctaaggcttc ttgagcgtta taaacttcac catctgaccc
     7921 tggaataacg ggcactcctg ccttaatcat ttcagaacga gcattgattt tatcacccat
     7981 tttatccata accgatgcgg atggaccgat aaatttaata ttcatctctt cacacatggt
     8041 cgcaaacttt gagttttcac ttaaaaagcc aaaccctggg tgaatcgctt gggctcctgt
     8101 cacaatagct gctgacaaga cggaattcat attaagatag gattccttgg aacgggcagg
     8161 accaatacag atagcctcgt ccgccaagat cgtgtgcaga gcttccttat ccgcttccga
     8221 ataaactgca actgtggaaa tccctaattc tcgtgcagca cgaatgatac gcactgcaat
     8281 ttcaccacga ttagcaatta agattttttt aaacataagg gtttcttcct ccgcagaaca
     8341 atcattctca ttgcccacag gcaaaggtta atgttccact tgctgctagc ttgccatcaa
     8401 cttctgccct ggcttcaacg acagcaatgg taccgcgacg cttgataaag gttgctgtca
     8461 tcacaagttg atcaccaggg acgacttgtt ttttgaactt cactttatcc attccagcgt
     8521 aaaagaccaa cttgccttta ttttcttctt ttgacaattc taagacacca gctgtttgag
     8581 ccaaagcttc cataatcaga acacctggca tcacaggata gtgaggaaaa tgcccgttaa
     8641 agaaaggttc attaatagtc acatttttaa tggcaacgat atggtcgtcc gacacttcta
     8701 acacacgatc aaccaataac attgggtagc gatgaggcaa agctgcttga atttctctaa
     8761 tatccatcat ttgatccgca ccaatccttg tccaaattca atgacatctt catttgatac
     8821 caaaatttct gtaatcacac catcacatgg cgctggcact tcgttcatca ccttcatggc
     8881 ttcgataatc acaagggttt gtcctttttt tacggtatct ccgattgcca caaatggtgg
     8941 cttgtcaggg ctagctgcaa gataggctac accgactaaa ggactttcaa caatatcacc
     9001 ttctgctaca aaagattctg cttgtggttg ctcctctaca ggaacatcct taactgatgc
     9061 tggactagac gcttccgaag cagttggatt cggaacaagt tgtacctgtg gtacaggcac
     9121 agcatgttct tgatttgatg tcgatgcatt gaggtgttgt tcgtttttac taaagattag
     9181 ctcaccttca tttgttttga ataaaaattc acgtaggctt gaggtatcaa actgagccat
     9241 caaatctttg atttcttgaa tattcaacct actcctccca acatttgaaa gctaatacag
     9301 cattatgacc accaaatcca aaagtatttg aaatggcata gttgatagct gtttcttttc
     9361 cttctccaaa gatgacattt gcttcgatat cctctgataa agcttgtgtc ccagccgtca
     9421 tcggaacata gttatgacgc atagcctcga tagtggcaat agcttcaata gcgcctgctg
     9481 ctccaagaag gtgacccgta aacgattttg ttgaagacac cggaacatcc ttaccaagaa
     9541 cggctacaat tgcttgactc tctccttttt cattagctgg ggttgaagtt ccgtgcgcat
     9601 tgacataatt aatagcactg gcttcaatac cagcttcttg taaggctaag tggatggctt
     9661 tacgagctcc taatccctca ggatttggag atgtcatatg gtaggcatcg caggtatttc
     9721 cataacccac aatttctgct aagattgtcg ccccgcgttc ttgcgcatgt tctaggcttt
     9781 ctaaaacaag cattcctgat ccttctccca tgataaaacc atttcggtct ttatcaaatg
     9841 gaatagagct tctgcttgga tcttcagttg ttgagagagc tgttaaactt tggaagccag
     9901 caatggcaaa cttagttatg gccgcctctg acccaccaac tatcatcaca tcttgagtcc
     9961 caaatttaat ggcacgaaag gcatccccaa tcgcatcatt tgaagaagcg caggcagtat
    10021 taattgattt acatactcct tgagctttta aagacatggc gacatttcct gcagccatat
    10081 ttggtagcgc ttttggcaac gtcattggct tcacacgttt tggccctttt tcatgtaagc
    10141 gaatcacctg ctcttcaatc tccgcaattc caccaatacc tgaagcaaca ataacgccaa
    10201 atcgatcgga atcaatcatc tcaatattta aatcagcatg attaatagcc tctttcgctg
    10261 cgtaaagagc ataaagagaa tatctatcga aacggttcaa atcttttttc acaaagtatt
    10321 tgtcaaatgg aaaatcctga atttcagcag cattcttgac tgcataatca gtcgtgtcaa
    10381 atttagtaat aggaccaata ccaatttggc cagctttcag attgttccaa aacgtttcag
    10441 gatcatgccc gattggagat gttagaccat aacctgttac cactactctt ttaaatgtca
    10501 tttcactacg tctccttatt gcattgtcat accgccatca atagcgataa cttgtcccgt
    10561 aatataatct tgttccacca agaagcttgc taagtgagca acttcttgag cttttccaat
    10621 acgttttatt gggatttgac ttaagatttg ctcttgcatt ttttcaggaa ggacacctgt
    10681 catgtcggac tcgataaatc ctggagcaat agcattcacg caaatgttac gagcagcaac
    10741 ttcacgggca acagacttgg taaaaccaat cattcctgcc ttagaagcgg catagtttgc
    10801 ttgcccaata ttgcctgtta aaccaaccac actagagaca ttaataattg ctccttggcg
    10861 ggccttgatc attggtttta acactgattg agtcatgtta aaagcaccgg tcaaattgat
    10921 tttcaagacg cgctcaaaat cctcttccgt cattttaagc atcaatttat cattagtaat
    10981 gccagcattg ttaactaaaa catcaatcga acctaaactt tcgatagctt cattgaccat
    11041 acgtttagcc tctgatgctt ctgaaacatc cccagagatg gtaacaactg taacgccgta
    11101 gtcagtaaaa ctagcaacaa gctcctcaga gatagcagag cgaccattta agacaatatt
    11161 agctcctaaa ctggcgaatt gatgagccat tgctaaaccg atacctctcg ttgagcctgt
    11221 gataaatata ttttttcctt taatttccat gaatgtcctc tctatctaaa aataaacgta
    11281 agcttaccat gttttcaaca ctagtacata gtaaattttt atcaattttc ttcacaaaac
    11341 ctgtcaaaac cttacctggt cctacctcaa tgaattgtgt tatgccactt tctactaaag
    11401 tcgcaacact gtcataaaaa cgaacaggct ccatgacttg acgggctaat agttctggga
    11461 tacggtcttt ttccataata ttagcttcgg tattaccaac caaaggagtc ttgaagtcac
    11521 tgaagttgta tctttccaac tctttagcca acaagcggct agctggttct aacaaagcag
    11581 tgtggaaagg acctgacacg tttaaaggga ttaaacgctt aactcccctt tcctttaaaa
    11641 gctcaactgc cacgttcaca gcatctgtct gaccaccaat tacaatttga ctaggagtat
    11701 tatagtttgc tggagcaacc actccatgtt tagcagctat ttgacagact tcttcgatga
    11761 cttgcacgtc tgtattcata acggcaacca tctttccaga tccttgtggt gctgcttcct
    11821 ccatcaagcg ccctctctta gctactaagg atagggtatc ttcaaaagag agtgcccctg
    11881 acgctaccaa agctgagtat tctcctaagg aaagaccagc taccatatcc ggtttaacgt
    11941 gatgtaagcc caaaacacgg taaatagcaa ttgatgatgt caaaatagct ggttgcgtat
    12001 agctagtttg attaagtttt aactcgtcac tatcaatcaa acggcgcaaa tcgtatccca
    12061 atacttgact agcttgatca aaggtttttc ttacaatagc aaagttatca taaaaatccc
    12121 ttgccatccc taatttttgg gcaccttgac ctgcaaataa aaaggctgtc tttgtcatta
    12181 tcattatcct tcatgtgttt atctactttt ctattgaaac agattgccag cgcttagctt
    12241 cattttgaat aacacgagct gcaccataat aaatatcttt taaaatcgtt tcacagcttt
    12301 cttcttttct cacaagccct gcaatttggc cagccataac agatccattg actacatcgc
    12361 cttcaataac agcatgtcga agcgatcctg ctcccatttc ttcaatatca gtagctgttt
    12421 tttgaccaat taaaaatgct ttttctgctt tagcgtaagc tgaggtcaat ttatttttaa
    12481 tagaacggac agggtggccc acaacctgcg cagaaatcac cgtatcaata tcttttgctg
    12541 ctaagatttt atctttaaaa ttttggtggg cattggattc tttagcaaca acaaagcgag
    12601 ttccaacttg aacagcctct gctcctaaca taaatgctgc tgctgcacca tgaccatcag
    12661 ctataccacc tgccgcaatg acaggaatcg aaaccgcttc aacaacttgt cttactaaag
    12721 acatagtcgt taacttgcca atatgtcctc cagcttccat accctcagca ataacagcat
    12781 ctaccccaag cttttccata cgtttggcta gcgcaacgct tgggacaaca ggaacaacga
    12841 ttatacccgc ctggtgcagt ctttccatat actttcctgg atttcctgcg cctgttgtta
    12901 ctactttaac accttcttca atgaccaaat caacgatatc atcagcaaaa ggagataaaa
    12961 gcatgatatt aaccccaaaa ggtctatcag taatagcttt gacacgatca atattagctt
    13021 taacgacttc tttgggagca ttgccaccac ctataatgcc taaaccacca gcattagaaa
    13081 ctgcacctgc taaatcacca tcagcaaccc aagccattcc tccttgaaaa atggggtaat
    13141 caatattaag taattctgta atacgtgttt tcataataac tttctataaa aaataaggag
    13201 aataatttga taatcaaact attatagtaa gaagaaagag cgagctagat cctaaaaaga
    13261 gtctaatccc accctaatgg tttgattaat acttattgtt tttttagtga tgaacatgaa
    13321 cataacagca gtaagctttt catagacttc tgatgttact tgtcactttt atccttattt
    13381 tgacttttcc tcaacgtaag caacaaggtc accaacagta tttaatcctt cttctgtttc
    13441 aatttgaata tcaaaagcat cttcaatttc tgaaataact tggaaaacat caagtgaatc
    13501 tgcatctaaa tcatcaaatg tagtttctag tgttacttct tctgtctcct taccaagttc
    13561 ttcaacaata atttcttgta ctttttcaaa tactgccatg tttatttctc cttaaaaaat
    13621 ataaatttgt ttttataaat gtgctaggca catgaataac tagattttaa caattagact
    13681 tccccatgtc aaacctccac caaaaccgga aagtaagatt ttttgggtac catctaacct
    13741 aatctgtccc ttttgaacag cctctgacaa gaggattggg atactagcag cactagtatt
    13801 accataacgc atcatgtttt caaggaattt ttcccgagga acatcaatct tgcgtgctat
    13861 tttatcaagt atacgacgat tagcttgatg caataaacaa tagtctatgt catcttttgt
    13921 aatatctgat tgcgccatta gtgtgaggat gctttttgac acatccctaa tcgcaaaatc
    13981 aaatatggca cgtccatcca tctgaatagt cgctatggct tttttgccaa ttgagtaagg
    14041 agatgaaaga ctagtttctc ctgaaatcaa actctgacat ctcgcaccat ctgtgtgtaa
    14101 tgtttccgct aaaacatgtt tatctttact ggcttccagt agcacgccac cagctccgtc
    14161 tccaaaaaga acggctgtcg ctcgatcctg ccagtttact aacttagata aagtttctgc
    14221 acctattacc attccatttt ggtaggcacc tgatgcaata agcttatctg ccatagccaa
    14281 ggcaaagaca aagccactac aagcagcagt catatcaaaa gcaaaagcac ttgtagccgc
    14341 aatagctgct tgaactttcg cagctgttga tggcatagtg gcatcagggc tgatagttgc
    14401 aacaataata aaatcaatag catcagcttt taacccagac tgagttaaaa gctgatcagc
    14461 aacctgaata gctaggtcac tagtcgtttc atctctagaa atatggcgtt ctgctattcc
    14521 tgttcgagaa aagatccact catgactagt gtccattatg ctagctaaat cattattagt
    14581 cactaactgc tgtggaacat agtgggctac ctgactgatt ttagaaaaaa tcatttaaac
    14641 caaatcctcc aaaaattgat gtagattccc tagtccacgc accaatgcct gcatctcttc
    14701 atcactcata tcagcaatga catgtccaac catattttta tggaactttg catggaggcg
    14761 gtccaaaagt cgaccccttt ttgttaatga caggtaaaca actcgcctat ctgagcgtga
    14821 tcgcgttctt gcgatataac cttttgcttc taatttattt aagctagtcg ttactgtccc
    14881 taacgttacc attaattctc tggcgatatc acttggagtc acctgatcat atttgccgat
    14941 aatttcaata gtgtgcatct cttttaaaga gacatcacta aactgactcg tctttaagct
    15001 catttcttca ataaccaaaa tccggttgaa aatatcaact aagtattggt taattttgtc
    15061 atattccaag taaacacctc ctagcaataa actttgacaa tcaaattata tcaaaggtca
    15121 aagtattttg caagcaatag ctgccttact taccttgaaa atttggtcgg cgcctttctc
    15181 caaaagctat gacaccttct ttaaaatctt ccttgaaagc tagctcctct tgaatagcaa
    15241 gctctgcctt agcataatct tcccatcctg tgaaaaagct ttgccagacc aatgatttca
    15301 ttccagcata agaatttgaa gagccacgtc tcaatcgctt taaaagttga agacaaactt
    15361 tgtctagttt atcagattct gccgtacggt agacaaaccc ataatcgaga cctttatcag
    15421 cagtaattcc ttcacctgtc atcacaaggt gagttgcacg attaagtcct actgcacgag
    15481 tcaatagaaa taaaccaccg gcatccggtg ctagtccaac atttacaaaa gcttggataa
    15541 attttgtttg agtactagcg atacaaaagt caacagctaa agctatatta aaagccgctc
    15601 cagctacagc tccatcggcg caaaggatga ctggttttgg caaatgcttg attgcaaaag
    15661 aaatttcttg taccagttca gcaatcttga ctagcgactg cacattatct tttgcaacag
    15721 cttcttgcat ttcaactagg tcaccaccaa ctgaaaacac ttttccaacg gctttaatta
    15781 ataaaaaacg cacagatgta tcgcgtttaa cttctgctaa tgctaccaga atctcttgac
    15841 aaattggaat attaaaaccg tttgaaacct ctggacggtt taaagtcaat gtcgcaagat
    15901 catctacaac atcaaagatg atgtgtttaa actgcataac aatcctcttt tctgataatt
    15961 tatttgacta agaaattatt tctctgtaaa atcatttgat agtcaaatca attacctaat
    16021 tatgatatac taaataaacc attttgacaa gagaaaaaaa cgatatctat aaaagaaaac
    16081 gttttctcta actgttttga cgtaaaaaaa cgtataactt cgggaaaatt atcctgagat
    16141 tatacgtttg acatctttaa atatcctcta aggcatcttt cactttatca aaaaaacctt
    16201 ttttctttgg atgtaacatt ttttcaccac tcgcttctgc aaatgcttgc aaggcttccc
    16261 tttgagcgtc attgagtttg gttggggtca caatattaac ggtaacatgt tgatcccctt
    16321 gacctccacc acggagtttt ggtgctcctt tgcctttgag acggaaggtt ttacctgttt
    16381 gtgtcccagc agggatagcc atctcaacat cgccatgaac cgttggaatt tcaacagtat
    16441 ctcctaaggc tgcttgagta aaagaaatat ctaagttgta gtaaatagtg gaaccattgc
    16501 gttcaaattg cttacttggt aagacattca aaataacaaa taaatcacca taaggtccgc
    16561 cattaaagcc agcttctcct tgaccttgta aacggatttg ctgaccagtc tctacaccag
    16621 ctggaatctt aacagacact ttatgagctt gcttttcatg accagtaccg tgacaggttt
    16681 gacagggttc tttaatttcc ttaccactac catgacaaat atcgcaggtg acttgtcgac
    16741 gcatcatacc aagtggtgtt tgggtgtcaa ttgtcattac acctgaacca tggcacttac
    16801 gacaagttac tggagcggta ccaggttttg cacctgagcc taaacaagtg ccgcaggttg
    16861 cttcgcgatt atagctaact tctttttcaa caccaaatac agcctcttca aaagataaat
    16921 taacacgata ttgcaaatcg tcaccttgac gaggggcatt tgggtttcgg cttccaccgc
    16981 caccaaagaa gcttgagaag atatcttcaa aaccaccaaa gccacctccg tcaaaaccac
    17041 caaagccgcc tgctccgcca ccaaagccac cttgagcacc tgcagcgccg tattgatcat
    17101 aagcagcacg cttttgtgaa tcacttaagg tttcgtaagc ttcttgaaca tccttatact
    17161 tttgctccgc tccagcttct ttattgatat ctggatgata ttttttagac atttttcgat
    17221 aagctttttt gatatcgtcc tgagaagcgt ccttagaaac ccccagacga tcgtaatatt
    17281 ctgtattgtt cataatgtaa gataccaagc ggtaaaacga ctcaatgaaa aataggaaat
    17341 ccgacaaaga tactctcgta tctaggaggt atttctcttt tttcgcaggg tcgtaggcgt
    17401 gttcaaatcc gcaaaagagt ctttacacgc tttagcctgt gttcgaataa tcgaacttgt
    17461 attcctttct taaaatattt tgacgtcagc atttttacat tttatttagc caaaaacaga
    17521 ggtttggtgc aacctctgaa ttcggatatt aatgttacta gataactaaa tcattacttt
    17581 tctgtaaatt cgccatctac aacatcatca ttatttgctg aatcattagc ttgtgcacct
    17641 tctgcacctt gtgctgcttg ttgagctgct gcagcttgct cgtacatttt aacagccaaa
    17701 gcttgcgctt tttcatttaa tgcttcaagt ttagctttca tgtcgtcaag gttgccagat
    17761 tcttgcgcag cttttaactc gtcaagagct gattgcgctg catcgcgttc tgtatcaaag
    17821 cctttacctt cagtttcttt gattgttttt tcagtagcaa agatagcttg gtcaacttcg
    17881 tttttaaggt caacttcttc tttacgtttc gcatcggctt cggcattagc ttcagcgtct
    17941 ttcatcatgc gatcaatttc ttcttcagaa agtccgtcgt ttgatttgat aacgatgtgt
    18001 tgttcctttt gcgtaccaag gtctttagct tttacagaaa caataccgtt tttatcgata
    18061 tcaaatgtta cttcaatttg tgggattcca cgaggtgcag ctgggatatc agtcaattgg
    18121 aagcgaccga gtgttttgtt atctgctgcc attgggcgtt caccttgaag aacgtggata
    18181 tcaacggctg gttggttgtc tgctgctgtt gagaagactt gtgatttaga cgttggaata
    18241 gtggtgttgc ggtcaatcaa tttagtgaag acaccaccca tggtttcaat accaagtgac
    18301 aatggtgtta cgtcaagaag gacaacgtct ttcacatccc cagtgataac accaccttgg
    18361 atagcagcac ccatggcaac cacttcatca gggtttacag atttatttgg ttctttacca
    18421 gtttcagctt ttacagcttc gacaactgct gggatacgag ttgatccacc aacaaggata
    18481 acttcatcaa tttctgacaa tgacaatcct gcatctgaaa gagcttgacg aactggagtt
    18541 ttcgtacgtt caacaaggtc acgagtgaga tcgtcaaatt tagcacgaga taagctcatc
    18601 tccaagtgaa gaggaccagc agaaccagca gtgatgaacg gtaatgaaat ttgtgtttgt
    18661 gtcacacctg aaagatcttt tttagctttt tcagctgcat ctttcaagcg ttgaagtgcc
    18721 atcttatctt gtgataagtc aataccattt tctttcttaa attcagtcac taagaaatca
    18781 ataattttct ggtcaaagtc gtcaccacca agtttgttat cacctgctgt tgcaagaacg
    18841 tcgaagacac catcacctaa ttcaaggatt gatacgtcaa atgtaccacc accaaggtca
    18901 aaaactaaga ttttttcatc cttgtcagtc ttgtccatac cataagcaag tgcggctgct
    18961 gttggttcgt taacgatacg ttctacttca agacctgcaa ttttaccagc gtctttagtt
    19021 gcctgacgtt gtgcatcgtt gaagtaagct ggaacagtaa taactgcttt ttctactttt
    19081 tctccaagat agtcttcagc ataaccttta aggtattgaa gaatcattgc tgaaatttct
    19141 tgaggagtat attctttacc atttgcagaa actttttcag aagttcccat tttagattta
    19201 atagagatta ctgtttctgg gtttgtcact gcttgacgtt ttgcagcatc acccacgata
    19261 atttcaccat ttttgaatga tactactgaa ggagttgtac gattgccttc tgggttagca
    19321 atgatttttg attcagtccc ttcaagaact gctactgctg agtttgttgt acctaagtca
    19381 ataccaataa ttttagacat gttaatacct cttattttat aatactttat tactttttat
    19441 ttcaatttat cttagtaagc actcgaatta ttttacttcc aattctaagc aatcactata
    19501 gtttaatcag caagcgaaat agcttctaac ttgctatcta gtttactgtc attacggaca
    19561 aaaacgaaaa ctcatttacc ttagttataa acaactacca tcgctggtct tagcagacgc
    19621 tcgtgcaatt tatatccctt ttgaaagact tctgcaatgc tatcggctgg atgttcatca
    19681 tcggctggga gggtctgaac tgccatatga aagttgtggt caaacgagtc aacttctact
    19741 tcttctacgc cttcttcctt tagtgcttga ataaggctat cacgagtcat ttctaaacct
    19801 tttttaacat catctgtcaa cccttcaaca gccaaagcac gttctaaatt gtcaagcgat
    19861 ggtaagattg cttttgccag atcctgagaa cgatagcgtt gaagttgttg acgttcttca
    19921 ctagagcgac gctgtatatt ctgcatttct gcatgagctc gcaagtattt attttcaaac
    19981 tcatcagcac gttcgtttgc aagttctaac tctgattttt caggagtttc ttcaataact
    20041 tcctcaactg tctcttcagt ttcagtggct tccacttctt cttgtaaatc gtctttttta
    20101 atttcttctg acactgagtg cctcctttta aataacttat tgaatactgc cattatcagt
    20161 ggacttcata atggttagaa tttaggtatc gataataatc acctaattta gcagccaata
    20221 cctttccaat aatgtttacc aaactaacag acctacgata atccatatca ataggaccaa
    20281 tcaaactcag gagtccaaac ccacggtaag gaatcaaaaa tttgtgagtt aaaactgaca
    20341 catctgcaag tgcggcttct tgactatctg ccacttggac agaagccatc tcaccttctt
    20401 tcagactttg cctcaaagaa attgctactt gctgttcatt atccaaaaac tgatacgttg
    20461 atagatctga atacgttaaa gaatttacct tgccagcaac aaataccgtt tccaaaaaca
    20521 gctctgaaaa aacataatca aatagttgta aaacattatc cgtagtcaca aaatactttt
    20581 gaacgatctg aggaatttct gtcctcaact tataatgaat atctatgaca ctactatcca
    20641 gcaagcgctc ctctacgata gctttaaatg ctatcaagtc acgtgtcaaa aagtttcttg
    20701 gaatagcaaa ctgcactgtc actggcttag attcatctaa agtcatgact gctagagcat
    20761 catggttgct aagctgaaca acatcaaacc ctgttaaacg ttgacgagct ggctccacat
    20821 ctaaaataac ggatgtatag cccgtcatct ccgctaaaat gtgactagct ttttgaagca
    20881 tgtcttctaa tttgaatgct tcaaaatcaa aagtttttat gacatgataa atatcttgct
    20941 catcaatact atctagcctg agggagtgct ctacaaaata cttaaaacca gctggacttg
    21001 gcatccgtcc actagaagtg tgcgcttttt ccaacaatcc caacttctct agttttgcca
    21061 tatcattacg aatagtggcg ctactagaat caatcgttct ctgtaaagct ttagacccta
    21121 ctggttcatg agtttgtgta aatagctcaa cgattaaatt caaaatatca ttttgacgtt
    21181 gtgtaatcac aaaccaacca ctccctttcg tttagcactc tatttagtag actgctaatt
    21241 tataattcta ttatactctt tatgggagac atgtcaagaa aaaaactcaa aaaaattagc
    21301 actcttttat aaagagtgct aatttcagtc atagtttgtt aaatcgttac tttcaatgac
    21361 ctgaatcagt cgcctagcat aggttttatc agtataatgc aaatactttt gtaaactttt
    21421 agctggtgct ttataccctt tttctgtagc aagattacga tacaaacgct tatcgacttc
    21481 tttgccctgc cgaagcattc gtaaataatc tctaattgca ctagcgtcat ctttataaat
    21541 agcatatctc acgttttggt tggtttgttt aggggacttt agggtaatgg ctgcttgtcc
    21601 tggagttgct ttcttgctaa aaagattatg atacttagac gctagtaatg tttttccatc
    21661 atgggtttcc aaaagaattt gagcaatcaa aatagatggt ctaatgccat aatattttgc
    21721 caatggttta acttctttac ccatttttgt aataaattgt ttttggctgt agttcaccct
    21781 tacttcttta tctgcactag ctatcctttg gctactcagt aagggacaaa caatcagcaa
    21841 taaaaagcaa gctaggagcg ttaaaaaata cggaaacttt agtcgttttc tcatcgtttc
    21901 tcctttaaag cagcaatgta ctcttccaac gttaggttgt gctgagccat ataacgagca
    21961 gacgccttgc ctacatagcg gtaatgccaa tcctcataat caacccctgt actagtcttt
    22021 tttccttctg gaaagcgcaa gacaaaccca taatcaggtg caattttttg aactgcttta
    22081 gataccgatg ggtcactggc atttaaagta tctacagtgc tcatgtcaat agcaagacca
    22141 gtgtgatgtt cactagtccc tggcggctgt gaataggttt gcaccaaagc ctccgcagct
    22201 tcttgtgtca atgttggatc gttagccatc tcttttttaa tataagattg gtaaagctct
    22261 gtttggtagt ctacggaacg gtacccagag ataagatgtt cttgcgagtc gatagctcgt
    22321 gctgctgcta aaaagtcact agtggcttgc tcaatgcgtt tatccacaga aataccatta
    22381 atgtcagcta attcaggact catttctttt gtaatgtgat cgcggtttac taaaaccaac
    22441 tcccaatctt caacagatac cttaggtaaa gctcgtaaac ggtccgtttt tttgatatct
    22501 ttttgttgga tttctttttt attcaactga gttggtgtta ctgactcttc tggttttata
    22561 aagaggtaaa gccctcctaa aaaaacaata acaattagca attgcactaa atagtttaac
    22621 gaattatatt tcatctgacc gttcttctat tatttcacga ccgcggtagc ggtaactcat
    22681 atctccaata gtctttatcg taaattggcc atcatcaaat tcaacaactg taacgctccc
    22741 attatcaata tactgtttgt ctcgatctgg atcaatcaac cacagaaacg ttccaattgt
    22801 cataccatgg ctaaccacaa gagcatttcc gccgccagca ttttgaatgg acaaggcaat
    22861 agcttcaaac ccctcccaaa tgcgcttacg aagaacttcc catggttctg cccaattagc
    22921 ggtatctact tccacgatgc tttctgccag ttcagaatag ggaacatcac gtaggttatc
    22981 acgattttca aaggcttttg ttcttggaag gacacctaga aataattctg aatcataagt
    23041 cccttctaga ctcccaaaac accactcacg aatacgatta tctttagtat aaggcaaaaa
    23101 ttcgttttct gattctctta aaataatttc tattgtctgc atggttcgac ctgaatcact
    23161 tgaaaacgca gccttaaatg gtatagttgc atcttttaaa cctaggccaa gttctcgaat
    23221 accttcttct cctttttttg taagaggtgt gtcactccaa ccctgagcgc gaccaatggt
    23281 attaaacatc gtttttccat gtctggcaat atacaacctt gtttttgtca tttcaacctc
    23341 ctaaactgtc ttattaatta ttatagcatt taaagaaaac acttgcaaaa cacttcctga
    23401 tggctatttg agatcaaata gaccactgac ttattgtcta ttttattaaa aacaatgcta
    23461 ttgctacaat tcaaatcatc acataaattt ccaaacgatt acatttgtgt gtttcgctca
    23521 aatatatata acaacagacc cacactacaa ctaaactgac gttacaaaat gatgtcaaaa
    23581 cagtaacaaa atctaactat ttgtcaagaa aacgatatta aattttcaca caaatatctt
    23641 ataatgagga tgcaaccaat aaaaagataa gacattttat gttgcaaaaa aggctgcttg
    23701 gaaacttcca tgcagccttt ttttaatacc tttttccaaa aatagctgaa acaagtacaa
    23761 ttacaattgc tgctcccaaa atggacggga aaatagccat acctgccaac tgaattcccc
    23821 aatccccaaa aagcctttgc ccaacagctg accctatgag acctgcgata atattagtaa
    23881 aacaacccat ggactggctt ttttcagtca ttttacctgc tatcatgccg ataaaggcac
    23941 ctacaattaa agaccatatc atcgttaaca cctcctttct tgtaaaatcc ttttagaaga
    24001 actgctatcc attaaatgtt cttaacttta gttgattcct ttaccttctt ctttagtaag
    24061 tgtttccgtg cctgagtaaa atagaaaaaa caattccttc tattaagata gatagaccga
    24121 gaacgactag aagtcttcac acactaaata acttagcaaa ctttatcaca cagctaatcg
    24181 ctaataataa tgtggacaaa cgtgatggtt cattaaatac ccgtcagaaa ctcctgaagg
    24241 ttctaaagca atacctgtca gtcttatttt agcatagatg atggtctttt tataggcggt
    24301 cactaacatg acatacaaaa aggcagcctg tgaaagaccg accgcctttt tttcagagac
    24361 aaaatacttt aacttattgc tatcagcaac tatcaatctc gcaatttttg caattcttgt
    24421 gccaataatt gttgagcgac ttgtggatta gcttgacctt tggttgcctt catcaagaag
    24481 cctgtgaaag ccttatcagc attacgtttg cctgatttga aatcagccac tgcagcttca
    24541 ttatcagcaa agacttggtg aataattggt accaaaacag cgggatcaga aatctgaaca
    24601 agtcctgctt tttccacata agcacgtgct gagccaccgt ttttagccaa atgcacaaaa
    24661 accttcttag ccattttaga agagattgta ccatcagcaa tgatagcaat catctccacc
    24721 aaattttctg gtgtcagagc gatttcttca atggttttgc cttctgcgtt taagaattgg
    24781 gcaacttctc cttgcaacca gttagagact tgcttggcat cgccaccaag acttactgca
    24841 gtttcaaaga aatctgacaa ggctttggta gctgttagct ggctagcatc ataagctgag
    24901 agaccaagtt cctcttcgta tttagcacga cgttgagctg ggaattgagg taattgagca
    24961 cgcatctcgt caatccaagc atcatcaatc tcatacaagg gtaggtctgg ttctgggaaa
    25021 taacgatagt ccgctgcccc ttctttgacc cgcatcaaaa tagtcccctt attcgcttcg
    25081 tcatagcggc gcgtttcttg gcgtatcgcc ccacctgaac gcaagagttt ggcttgacgt
    25141 tccacctcaa attcaagccc tttacggaca tttgagaagg agttcaagtt tttcaattca
    25201 gtctttgttc caaattgttc ttgcccgtaa ggacgaaggg aaatattggc atccacccgc
    25261 atagagcctt cttccatctt gacgtcagaa atgcctgtgt actggatgat ttctttcaga
    25321 gctgtcaaat aagcataggc ttcttcagga gaacgcatgt cggcttctga cacaatctca
    25381 atcaaaggaa ctccttggcg gttaaggtcc acataagaat aaccatctgt gccgtgagtg
    25441 tttttaccag catcttcttc caagtgtgcg cgttcaatac gaattttctt ggttgaaccg
    25501 tcttctagtt tgatatcaat ccagccgttg tagccaatcg gctcatcaaa ctgtgaaatt
    25561 tgataagctt taggattatc tgggtagaaa taatttttgc ggtcaaagtg catctcttta
    25621 tggatgtcca tattaagggc aagcgctgct tttatgcccg catcaatcac ccctttgttc
    25681 atgactggta agacccctgg aaaagaccaa tcaatcacat tcgtgttggc atttgggtcc
    25741 tcaccaaagt gagctgacga aggtgagaaa attttggaat tggtatttaa ttccacatgg
    25801 acttcaagcc caataatggt ttcaaaattc attacttgtc acctccaaaa ataatcggtt
    25861 gttgcttgtg ataatctgtc accgcttcaa aggctgctgc tgcttgatag atggtttctt
    25921 cagtgtattt cggaccaatt aattgaagcc ctactggcaa gccatcgacg aatcctgctg
    25981 gaatggaaat tcctggcaga ccagccaagt taactggaat ggtcaataag tcggccaaat
    26041 acatggcaac aggatcgtgg ttgagtgtgt ctaagccaaa agcaaccgtc ggtgttgttg
    26101 ggcctaaaat aagatcataa tccgcaaaga ccttatcaaa atcttcaata atcaaggtac
    26161 gcacttgacc ggcctttttg aaataagcgt cataataacc tgatgacaaa ctaaaggtcc
    26221 caagcatgat acgacgttta acctcatcac caaagccttg gctacgagtg ttaacataga
    26281 tttcatccaa gtttttagca tcgtcagcac ggaatccata acgaatgcca tcaaaacgtt
    26341 gtaagtttga ggacgcttct gacgaagcaa taatgtaata gacagccaca ccatatttgc
    26401 tatgtggaag actaacttcc tcaacagtag ctcctaaggc ttcaaattgt ttagctgccg
    26461 caagaaccgt ttccttaatc tcaggatcaa tcccttcgcc aagatactct ttaggaaggg
    26521 caatcttcat gcctttaatg tcacgaccaa tcttagatgt gtagtctgca atgcggacag
    26581 gcgctgaagt ggcatccttg acatcgctac ttgcaatcac atttaataat tgggcgtttt
    26641 ctttaactgt cggagcaaaa ggtccaatct gatcaagtga acttccaaaa gcaatgagac
    26701 catagcgaga aacagtgcca taggttggtt tcaaaccgac aacaccatta aatgcagctg
    26761 gctgccgaat agaaccacca gtgtctgaac caagagataa acggacttgt cctgaagcga
    26821 ctgctgttgc cgaaccacct gatgagccac caggtacttt tgtgtggtcc caagcatttt
    26881 tcgttttctt gaaataagag gtttctgttg aaccacccat ggcaaattca tccatgttgg
    26941 tttttccaat gacaatcatg tctttagcgt aggcatttgc tactgatgtg gcatcaaaaa
    27001 tcggctcgta gttatacaac atttttgaag cggctgtggt taggatgccc ttggttgaga
    27061 tattatcctt aacagctagt ggaatacccg acatgaggtt atcagcatca atacctttag
    27121 catcaattgc cgcagcttgt ttaagagcag cttcttctga aacagtgata aacgacccga
    27181 cagcctcctc acgagacttg atgtcttcaa gtgttttttg agtcaattcg gttgcggaaa
    27241 tctccttagc tacaaggagg tcatgcaact cttcaatggt tttatgatta aaagacatta
    27301 ggcatctcct ccgtcatcca aaatagcagg taccttgata aagtgatttt ctttttcagg
    27361 aacattttta aagagcaagg cacggtctgt tccttcttca gcgacatctt gacgcatcac
    27421 atttttctta tctgccatgg ttgttgtaat ggcaacacct tcggtatcaa cttcgttcag
    27481 caattcaacc atgtcaacga ttttagatag ggtcgttgca aaggttgttg tctcactttc
    27541 tgaaaatgat aattttgata gcttcgcgac atggcgaact tcttcttcag aaattttcat
    27601 gatttctccc atccaagatg acaagaagta ttccagttcc aaagaacagc tctgctattc
    27661 tctaaaggta gcggaaaaac ttctcacatc atttttacat agtctcaatt attatatcac
    27721 aattgttccc atttaccata ggtgactaat gcaattctag aaagccatac agcaaaaaac
    27781 ttcctgacta aggtcagaaa aacttagtca ggaagtgtga caaactaaac tctatttgtc
    27841 ttgggtaaga ctgtggcctg aagctttgat ggcagcctga gcagccgcca agcgagtaag
    27901 cggcactcta aatggcgaac aagaaacgta ggtcaggcct tggctgtggc aaaaggcaat
    27961 ggaagcagga tcgccaccat gttccccaca aataccaagt ttcaagtcag gcttaaccga
    28021 acgggctaat gaaacggcgg tactaaagag acggccaatc cctttctgat caaaggtctg
    28081 gaacggctcc ttatcaaaaa tacccctgtc aacgtattct tccaagcatt ttcctacaac
    28141 atcacagaaa aagtaacggt ctttcaagtc ggtaatatgt ttacgaaggt agtaaagggg
    28201 tgctttattc taatttacca aatcctcaac gattgtaaca acatgtgatg tgataagcct
    28261 aagataaaaa tggtacagac tctagcattc aagagtttga agctttattt ttatattcta
    28321 atgctgaaaa gactagagtt tgtctaatgg ctgtgagacg atcctctaaa ccatcaactc
    28381 aaatcatttc tcaaacagct aaaatcctgt ctccttcaaa aaaacatgtg ttctatctga
    28441 cacagtccaa agtttagttg ccttttagac agcacaagaa tcatcaggac taattctgac
    28501 cagcatgtca catacctcat ctacctaacc catacataca gtaaaaccac atagagcaat
    28561 gattacggtt accaaactct tagtcactga atcaatagtt tggtaggctc ttttagtaat
    28621 cgttaataag cttagcacca agaacctgct caaagtgagc caaagaccac tcataagatt
    28681 cttttgtaag gctagcgaca gccgatttaa caatctctaa ttgataccca agatgataag
    28741 catcaatagc agtatgtaag acacagatat cagataaaac tcctgttaac actaattgag
    28801 tgatacctct ttctcgtagt ctaatatcta aatcagtccc cgaaaaagct gaataataac
    28861 gcttatcaat ccaaaaaact ctgggatgtt gcttcatata actgtaaact tcagctagtg
    28921 gaccataaag atggcgtcca gtagttcctt tgatattatg tgctgcaaat aacttactct
    28981 caggatgcca aggatcattt tgatcatgac aatcaatagc aaaaaaaata tagtctcctt
    29041 gatcaaatgc cgttttagtt acctctgcta ttttagtggc aatagcctga gcagatttac
    29101 ctgcacttaa tttaccatca tctgctacaa aatcatttgt gtaatcaatt gaaatcaatg
    29161 ctctcatcac tctctcctaa acagggaaac ctctcccctt atctcttata tatggcattg
    29221 tatcagtttt tattacaggt atcaagacat ctatttgcat ctaccattaa cagcaaaaaa
    29281 catctctttt caagagatgt tgtctttttc tatttaaaat tcttttaatt tagcaaaaat
    29341 accttcgttg ataactttga ggtatgtccc tttcatacca agagaacgac tttcaataat
    29401 ccctgcactt tctagtttac gcagagcatt gacaataaca gaacgggtaa taccaatacg
    29461 atcagcaata acagaagctg tcaatcgtcc ttcgttacca tctaactctc caagaattgc
    29521 tgcaacagct ttcatttctg aataagaaag cgtattaatt gccatgttga ccgctgtttg
    29581 tttacggatg gtgtcttcta agttttctgt ctgaagattt aatagttgaa tccccacaac
    29641 agtacttgag atctcaacca aaatcaaatc atcatcacta aactcattgt cattacgcca
    29701 gataatgagt gatccaaggc gcatccctcc accataaatc ggcgcaatag tcgttagacc
    29761 tcctggataa gtgtctttag actcaatagg gaatatagtc aattcatttt cgacagaaag
    29821 gttagcttct gtatcgtaaa ctcggctagc agcctttaca taagtatctg gaaattgttt
    29881 agcttcaaaa aattcctcaa cacgatcagt gttagtttta tatttcatgg cataaccaag
    29941 caatgtgccg ccgccattga taatacaagc attgcagtca atgatatctg ctaggcgaga
    30001 tgccattgtg ttatacggta attctgtttc taggctatct acggaacgct gcaaaataga
    30061 tgtgatttta cgagtttttt ctaataagtt aggcattttt ttccttttcc tttgaattat
    30121 ttgcgctttc attataacaa agctaactcg cttttgcaag gaattatcag aaaattttct
    30181 attcttacta caattccaac tattgatgcc ttattatcac ttcatttaaa ggagataagc
    30241 actagcttgt tagagcatag ggtcacattc ttttaagaaa cgctattttt attaatcgaa
    30301 gatgaacatt gcattaacgt ctatactggt ataagacacg tgtaatcttt tcttggacat
    30361 cttctaattc ttctacactt ggtaggtaaa caatacggaa gtgatctgga tctttccagt
    30421 taaaaccacg tccatgtacc aacatcactt tttcttgctt taataactgt aagacaaatt
    30481 cttcatcatc atcaatacga tacatctgac gatcaatttt cggaaataaa taaagacctg
    30541 cttcaggttt aactgccgat aagccaggga tagcattaat agcttcataa ataaaattac
    30601 gttgctcaaa aatacgccct cctggcagta acagtgcatc aactgattga tggcctccta
    30661 aggaagtttg aacaacttgt tgggctaaaa cattggagca taaccgcata ttggcaagca
    30721 tgtttaaccc ttcaatgtaa cctttaacat ggtctttagg acctgataag accatccatc
    30781 caacacgaaa accagcaata cgatgagatt tggaaaggcc attcatagat acacaaaaaa
    30841 catcaggtgc caaacttgca atagcaatat gctctttacc atccatcacc aaacgatcat
    30901 agatttcgtc ggcaaaaata atcagctggt gttctcttgc caaagcaacg atgtcttcta
    30961 aaatctcctt aggataaagg gctcctgttg ggttattagg attgatgacc acaatagctt
    31021 tggtgcgact cgtgattttt gatttgatat cagcaatatc aggataccaa ccagcttctt
    31081 catcacaaag ataatggacc gcttttcctc caccaagact cacacaagcc gtccataaag
    31141 gataatccgg cattggtact aaaacttcat cgccattatc tagcaaagct tgaagggata
    31201 tggatatcaa ctctgacacg ccatttccca aataaatatc ttcaatgtca acatctggga
    31261 agcccttgag ttggcaatat tgcatgatag ccttacgcgc tgaaaaaatc cctttactgt
    31321 cagaatagcc ctcacttagc ctcgcgttga caattaaatc acgaatcact tcatctggtg
    31381 cttcaaaacc aaaggcagca ggattgccag tatttaaacg cagaattttt tcaccactcg
    31441 caatcatgcg attagcttca tccaaaacag gccctcgaat atcataggca acatgttcta
    31501 attttgatga tttttcaata attttcatag tctcatacac ctcgtattcc atattataaa
    31561 ccaaaatact taaaatagaa agaatttatc catcaaagct taggacagcc aatcgtttta
    31621 acacaggtct tatgagacga taatacagtc tttagtttag ccaaaataat ggatcgcttt
    31681 caaaatgact caaaaaagag tataatgaaa aaaagaataa aagctattct tgtcaaactg
    31741 ttaaaggagg acagttctat gtcactaaaa tataaacgta tcctcgttgc tattgatggc
    31801 tcttatgagt ctgaattagc tttcaataaa ggcgttaacg tagcactacg taacgacgct
    31861 accttactac tagtacacgt tattgacacc cgtgccttgc aaagcgtagc tacttttgat
    31921 acttacatct atgaaaaatt agaacaagaa gctaaggacg ttttagatga ttttgaaaaa
    31981 caagcacaga tagcaggaat tacaaacatc aaacaaatta ttgaatttgg caatcccaaa
    32041 aacttactag ctcacgatat tccagatcgt gagaacgctg atttaattat ggtaggagct
    32101 actggtctta atacctttga acgcctcctt attggctcat cttctgagta cattatgcga
    32161 cacgctaaga ttgacttact tgtagtccga gatagcacta aaacactcta gtctattaca
    32221 attttcaaac accaaaaaac aagcagcatc tacaacgaaa ttgcttgttt ttttgtgctg
    32281 agctaaggct agtcaatatc tttttatttc ttgatattta aaagagtaaa cctctattta
    32341 tcgaatcgtt gtagtgattt ttgtaattgt ttgtctaact ctttttttat ggctacttca
    32401 ggtgcgtgac gctcttgcca atagtcaggt ttttgaattt tatgggtaac ggggtcaaag
    32461 tgtgccttgc catctggaaa aattttagcc atatttgctt catgtactgc ttcaaatata
    32521 ggttgtggat ctactcccat cagtacaaaa gaaccataag taaaataaag caaatccgct
    32581 aaggcatcaa cttgcccaat caggggcgtt tcaacatgtt ttttagcttg taccttatta
    32641 gatgcttggt caacagcacc atgcaaatcg aaaatagcct gtgtaaattg ttgttggtct
    32701 cccttgcttg ctgcgtaaag aaactcaaca atttcttcta ctttgaagcc tgacctataa
    32761 ccagcttctg aaatggtata actacgcggt gtttcaatag tatctgagtc catcagacga
    32821 tgaaaatctt tgactttatt aaaattttca tcacggcttt taaagctctt ctctacatca
    32881 aaatggatga gaccgtagtg agctaaggct ttggaaattc catcattatt attagagtcg
    32941 gtagtgaaat gggctccatc ttttaccaca gtttcagcat ttcccatagc aataccgata
    33001 ccaactcctg ataacatttc aaggtcatta tctgaatctc caaaagccat cacttcagac
    33061 aagtcaaatc caaacatctc tcccaaacgt tcaattcctt ttatttttga ttgatcaaca
    33121 gagatcagat ccaaggaata aggactactt cttgtaattt ttatatgagg gaacttctct
    33181 tgtattttct tagtttcagc ttgtgacgct accagaacaa cctgataaat aggctcccgc
    33241 ataatagtta ctaaatttct aaaactctga ggcttgattc ggcgaatcaa atgcttaaaa
    33301 ctaccctcaa ctgttcttgc ccagcttttg ggcacaaaac tactaatgac ttgtccaaat
    33361 gggctagtcc ccatatcaat aatacgcgat cctgctaatc cagaagctgt tccaagagaa
    33421 atttctcgct ttttttcgtt ggcatagcga atcactttgt aaatcatcga ctttggcaat
    33481 tgattctgat ataagacctt atctcttgtt aagatatatt gcccattgta agtaacggca
    33541 aaatctaatc caaaattttc tagaaaaggt tgcacaaatc ccggtccacg accagttgct
    33601 aaaccgacca taatgccttg ttttttgagt tgttggatgg ctttttgcgt tgttttttgg
    33661 atatttttac gatcattgag aagggtccca tcaatatcaa aaaagactgc ttttactgtc
    33721 aaaaccttct tttgcctcct gtgtttatga tagaatagat tatatcataa ataaaaggaa
    33781 gtttgacaat caaatgaaaa aaatcctagt cttacacact ggtggaacca tttctatgca
    33841 agctgataac tctggtaggg ttgttccaaa tcaagataat cctatgacga aaatacatgc
    33901 tgcagcccaa gatattcagc ttaccgttag tgattttcta aatcttccga gtcctcacat
    33961 cacgcctcac cacatgttat ctatttatca tcatattcaa gaaagaactg atgtctttga
    34021 tggtatagtc atcacacatg gaacagatac cttagaagaa acagcttatt ttttagatac
    34081 catggcattg cctactaata tacctgttgt cctaacaggt gctatgaggt cttctaatga
    34141 agttggtagt gatggcatat ataattacct taccgcactt agagttgcaa gtagtgataa
    34201 agctaaagaa aaaggggtac ttgttgttat gaacgatgaa atccatgctg ctaaatatgt
    34261 tactaaaaca catacaacca atatttcaac tttccaaaca cccacacacg gaccgcttgg
    34321 tatcatcatg aaaaatgacc tacttttttt caaaactgct gaacctcgta ttcgttttga
    34381 cttgagatgc atttctggaa ccatacccat tatcaaagca tacgcaggta tgggcgatgg
    34441 tagtatcttg agtctattaa ctccaggtag cattcaaggt ctagttatcg aagctctagg
    34501 ggcaggaaat gtcccaccat tagcagttgg ggagatcgag cacttaatta ctttaggtat
    34561 tcctgtcgtt cttgtttccc gttgtttcaa tggtatggca gaacctgtct atgcttatga
    34621 aggtggtggt gcgatgctac aagaagcagg tgttatgttt gtaaaagaat tgaatgctcc
    34681 aaaagcccgt ctaaagttat taattgctct caacgccgga cttactggtc aagagctaaa
    34741 agattatatt gaaggataat ctagcttcct gtagaaatgt cccactaaaa catattagtg
    34801 ggacatttct agtactttaa gctttaaatt aggacatctc ctaaatgtct ataataaaca
    34861 actatgtttc aaactatgag attgtgcact cataatcatt tctataacag tttgagacca
    34921 gtattccaat aaatccaact cttagcaatc agataccggg taaacaagtc tttattttgt
    34981 ctcattaagt atgagcttac ttgaataata acaaaactac ttgctcatcc ttttttagta
    35041 atgatgaaga cgaccttttt ctaagaactt ctttgtcttt taaaataaac aaagcacata
    35101 ttacccttta ttttagttct cgtttggaaa aaagaaagac attgcccaaa agataacaaa
    35161 gagttaaacc aaaggccact aatatgctag tactagaaag atgtttatca ccaagagaca
    35221 aggataggtg tttaaacatc aaaactgggc taatatctaa cttaaaaaaa tggtttgcta
    35281 aagtagcaga tactttatca aaaagaagga cataaagtat ataagctgtg attgactgat
    35341 aagttttacg aagtatatta aacaaaaatt gacacaaagc aataatagca atataaaaag
    35401 gcagttgttt aatcatccga tctatgacta ttccatagta tgcttgacca gtaaataaat
    35461 gaaatgctaa agcactaaga agataagtta aactaataaa taaaagagat aagccaaaac
    35521 taactagcag tttatagatt ataattaaag tacgattttg ttgtttgacc acaacattat
    35581 taatcgtacg gtagttatag tcatcactaa aaaagatacg ggctggtgtt aaaaagaaaa
    35641 gcgtcacaaa atcagtaata atattaatga tttgtatcat gatgacttgg ttaggtgtct
    35701 tgcgaaaact ataggctaca ccaacagcaa tgacaacaag tagcatacaa gaaaatagag
    35761 ctaaacgctc ttggcgtatc cgaaataaat ctgctttaag ataggaaatc ataaaaacct
    35821 ctttctaaat taatggtgat gctgcatctt tacctaacaa atcgaggtaa taatgttcaa
    35881 agctcacttg atgatgataa atgtcaaaaa tctcaacagg cagatctaga acaattttga
    35941 taagctccat tactgataaa gttggtttta ttagtagcat ctgaccatca gtctcaactc
    36001 taagccccaa ttctaaaagt ctatttttta ccagctgatc atcgcttgta tgaagggcaa
    36061 tttgtacttt tacttgagct ttaagctctg ctttgtccat actcttaata actttgcctt
    36121 tatgcataat cacgtaacga tcaacaacta agtctaattc tgataaaata tgactggaaa
    36181 tcaaaatcgt aataccatag caatctctta ggttcaaaat aatctgacgc atttctttga
    36241 ttcctgctgg atcaagacca ttaatgggtt catctaagat taaaaattct ggaaaatcta
    36301 gtatcgaaag accaatagcc aaacgttggc gcatccccaa agaataatct ttcacctttt
    36361 tctttttgct cactttttct aacccaataa gttccaaaac ctcatgtatg cgctctttcg
    36421 catcagctaa tctcaattgc aacgctgcat agtaaagatt atcatgagct gtcatattgg
    36481 gataaagtgt cggtgactca ataattgatc ccattcgata gggttgtaac tgtttgattt
    36541 gccctgaatc ttttccaatt aggccagata aaatacgcat taacgttgtc tttccagcac
    36601 cattttgacc cacaaggccg caaatttctc ctttgtaaat atcaaaagag atatcactta
    36661 aaacctgatt tttaccatag gatttattta cttgctcaat acttagtaac attgattgct
    36721 gtgtcatttt ccgctccttt tttgtactta tcaattaata caatatctta cacataataa
    36781 catctgtaaa cggtta
//
LOCUS       DAUNLR010000015        34747 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUNLR010000015 DAUNLR010000000
VERSION     DAUNLR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34747
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.015"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            20..793
                     /locus_tag="VLL59_000720"
     CDS             20..793
                     /locus_tag="VLL59_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HER6508863.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
     gene            1454..1741
                     /locus_tag="VLL59_000721"
     CDS             1454..1741
                     /locus_tag="VLL59_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HER6508864.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            1731..2066
                     /locus_tag="VLL59_000722"
     CDS             1731..2066
                     /locus_tag="VLL59_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HER6508865.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKISHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     QSDYIKLFK"
     gene            2218..2688
                     /locus_tag="VLL59_000723"
                     /pseudo
     CDS             2218..2688
                     /locus_tag="VLL59_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            2802..3152
                     /locus_tag="VLL59_000724"
     CDS             2802..3152
                     /locus_tag="VLL59_000724"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HER6508866.1"
                     /translation="MKLDSETISILQEWKAISQKEKAQLAVAPLSIESDFIFTYCTRE
                     GSIEPLHADYINNILSKVIKQHSLKKISPHGFRHTHATLMIEIGVDPVNTAKRLGHAS
                     SQMTLDTYSHATAV"
     gene            complement(3320..3712)
                     /gene="rpsI"
                     /locus_tag="VLL59_000725"
     CDS             complement(3320..3712)
                     /gene="rpsI"
                     /locus_tag="VLL59_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HER6508867.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3733..4179)
                     /gene="rplM"
                     /locus_tag="VLL59_000726"
     CDS             complement(3733..4179)
                     /gene="rplM"
                     /locus_tag="VLL59_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HER6508868.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(4397..4603)
                     /locus_tag="VLL59_000727"
     CDS             complement(4397..4603)
                     /locus_tag="VLL59_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6508869.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(4600..5299)
                     /locus_tag="VLL59_000728"
                     /pseudo
     CDS             complement(4600..5299)
                     /locus_tag="VLL59_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5435..6295)
                     /locus_tag="VLL59_000729"
     CDS             complement(5435..6295)
                     /locus_tag="VLL59_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HER6508870.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(6392..6910)
                     /locus_tag="VLL59_000730"
     CDS             complement(6392..6910)
                     /locus_tag="VLL59_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HER6508871.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            complement(6914..7660)
                     /gene="rlmB"
                     /locus_tag="VLL59_000731"
     CDS             complement(6914..7660)
                     /gene="rlmB"
                     /locus_tag="VLL59_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HER6508872.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDDILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(7707..8504)
                     /locus_tag="VLL59_000732"
     CDS             complement(7707..8504)
                     /locus_tag="VLL59_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508873.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMVAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQTNQSANQEIDSTSNPFKSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLSGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(8700..9113)
                     /locus_tag="VLL59_000733"
     CDS             complement(8700..9113)
                     /locus_tag="VLL59_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HER6508874.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(9106..10449)
                     /locus_tag="VLL59_000734"
     CDS             complement(9106..10449)
                     /locus_tag="VLL59_000734"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HER6508875.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFAIADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            complement(10477..10707)
                     /locus_tag="VLL59_000735"
     CDS             complement(10477..10707)
                     /locus_tag="VLL59_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508876.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(11186..11767)
                     /gene="cysE"
                     /locus_tag="VLL59_000736"
     CDS             complement(11186..11767)
                     /gene="cysE"
                     /locus_tag="VLL59_000736"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HER6508877.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTVRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(11776..12528)
                     /locus_tag="VLL59_000737"
     CDS             complement(11776..12528)
                     /locus_tag="VLL59_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HER6508878.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDDNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(12521..14653)
                     /gene="pnp"
                     /locus_tag="VLL59_000738"
     CDS             complement(12521..14653)
                     /gene="pnp"
                     /locus_tag="VLL59_000738"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HER6508879.1"
                     /translation="MSKQTFTTTFAGKPLVVDVGQVAKQANGATVVRYGDSTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVCYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQVDIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            complement(14933..15661)
                     /locus_tag="VLL59_000739"
     CDS             complement(14933..15661)
                     /locus_tag="VLL59_000739"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HER6508880.1"
                     /translation="MTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGIS
                     SYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGEST
                     CPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTARVPAIVSVFAGRIADTGVDPMPIM
                     EEALRICRQKEEVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDYS
                     LETVQMFLKDSTSLGFKILEDDNH"
     gene            complement(15674..17053)
                     /locus_tag="VLL59_000740"
     CDS             complement(15674..17053)
                     /locus_tag="VLL59_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HER6508881.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVSSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVIFYLVATVASVLRDASVAEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPSFLSKSQE
                     AINNVSEEI"
     gene            complement(17082..17366)
                     /locus_tag="VLL59_000741"
     CDS             complement(17082..17366)
                     /locus_tag="VLL59_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HER6508882.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKG"
     gene            complement(17359..19419)
                     /locus_tag="VLL59_000742"
     CDS             complement(17359..19419)
                     /locus_tag="VLL59_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HER6508883.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRILPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKPVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(19772..20041)
                     /gene="rpsO"
                     /locus_tag="VLL59_000743"
     CDS             complement(19772..20041)
                     /gene="rpsO"
                     /locus_tag="VLL59_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HER6508884.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(20217..20417)
                     /locus_tag="VLL59_000744"
     CDS             complement(20217..20417)
                     /locus_tag="VLL59_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508885.1"
                     /translation="MTMLGYRLSAEVLGSAILPLLVGYLIRQAIAQVYSDLKTAYWLF
                     GLASSVAYGGLVKAKRAHSTTR"
     gene            20543..20812
                     /locus_tag="VLL59_000745"
     CDS             20543..20812
                     /locus_tag="VLL59_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HER6508886.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIEHICFKTYRIADLDALTQLRPLRYAAH"
     gene            20913..21527
                     /locus_tag="VLL59_000746"
     CDS             20913..21527
                     /locus_tag="VLL59_000746"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HER6508887.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(21561..22103)
                     /locus_tag="VLL59_000747"
     CDS             complement(21561..22103)
                     /locus_tag="VLL59_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HER6508888.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(22233..22661)
                     /locus_tag="VLL59_000748"
     CDS             complement(22233..22661)
                     /locus_tag="VLL59_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HER6508889.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(22771..27168)
                     /locus_tag="VLL59_000749"
     CDS             complement(22771..27168)
                     /locus_tag="VLL59_000749"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HER6508890.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYENDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRTVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKRAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            complement(27422..29278)
                     /locus_tag="VLL59_000750"
     CDS             complement(27422..29278)
                     /locus_tag="VLL59_000750"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HER6508891.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHPNYDDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPERT
                     DLDRWVVLDKSIPSLADIPEEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHMTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            complement(29476..30735)
                     /gene="rseP"
                     /locus_tag="VLL59_000751"
     CDS             complement(29476..30735)
                     /gene="rseP"
                     /locus_tag="VLL59_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HER6508892.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVIFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(30808..31602)
                     /locus_tag="VLL59_000752"
     CDS             complement(30808..31602)
                     /locus_tag="VLL59_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HER6508893.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(31615..32364)
                     /locus_tag="VLL59_000753"
     CDS             complement(31615..32364)
                     /locus_tag="VLL59_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HER6508894.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNHRQRRFGKV"
     gene            complement(32583..32948)
                     /gene="yajC"
                     /locus_tag="VLL59_000754"
     CDS             complement(32583..32948)
                     /gene="yajC"
                     /locus_tag="VLL59_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HER6508895.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(33064..33438)
                     /locus_tag="VLL59_000755"
     CDS             complement(33064..33438)
                     /locus_tag="VLL59_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HER6508896.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKDVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            complement(33622..34734)
                     /locus_tag="VLL59_000756"
     CDS             complement(33622..34734)
                     /locus_tag="VLL59_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HER6508897.1"
                     /translation="MKQKNINKFVYRYGLTTAAAVLATFGGVANVSADAESMRYVGED
                     LQKELDKSSGEYVPKVNNSREGRLPNGQLQVEDYLTKIQSYLEEWKKRDDTWKEKVTK
                     SIQNGTFQGDKGDMGPEGKPGPKGDKGETGDQGPRGERGETGLQGPKGEDGKDGLQGA
                     PGERGEQGPAGPKGDKGERGEKGETGATGAQGPQGEAGKDGAPGEKGEKGERGEKGET
                     GATGAQGEAGKPGEQGPAGPQGEKGETGAQGPAGPQGEAGKPGEQGPAGPQGEAGKPG
                     EQGPAGPQGEAGKPGEKAPEKSKEVTPAPEKPAGKEANQTPGRRNGNMAKTPVANNHR
                     RLPATGEQANPFFTAAAVAVMTTAGVLAVTKRKENN"
BASE COUNT        10283 a         7662 c         6470 g        10332 t
ORIGIN      
        1 acactgatag gagataagaa tgaaaaagaa agagcgtcat gaaaaaattc tcgatatctt
       61 aaaagttgac ggttttataa aagtaaaaga tattattgat gaaatgaaca tctcagatat
      121 gaccgctaga cgagatctcg atacattggc agataaagga ttacttatca ggacccatgg
      181 tggtgctcaa tatttggatt attcttcagc aaaggacgaa ggtcacgaga aaacacacac
      241 tgaaaagaag gtcttacaga ctaccgaaaa aaaacaaatt gcacaaagag ctaaaaacat
      301 tattaaagat ggcgaaactg tctttatagg tccagggaca acattagagc atctagctgt
      361 cgaattaaaa aatagaaata tcagagttat tacaaatagc cttcctgttt ttttaatttt
      421 gcacccgagc actactattg atttgatttt aattggtggt gaatgtcgtg aaattactgg
      481 agcttttgtt ggtgctattg ccattaataa tctagaatca ctaacttttt caaaggcttt
      541 tgttagcgca aatgctgttt ataataattc tattgcaacg tacagtgacc tcgaaggaga
      601 agttcaaagg gttgcattga ataatgctgt tgagaaaatc cttctagttg atagtaccaa
      661 gtttgaaagt tatgacttct ataatttcta ccaactagat caagtggact taattgtgac
      721 tgataaaaat gtgacaactg atatcataga aaagtacaag aaattctcaa aaatcataat
      781 cgctgacaag taaaggacct actcatatta aaaagcactt cagggtttag atatatcccc
      841 tgtcaagtaa acagggagca tatctgaaag tagtgtttgt attataaaga agtttcttgc
      901 taacttattt tctggttttt ttcagactta tcagtcttgt actgttcctt tttctgatga
      961 ataacgtgga aataggcaga cagctatata tttcacctct agaatggttg ccattactgt
     1021 catcaagaca tgcttgttct ttatcgtatg gagtgaagct ttcttttaga catcaacata
     1081 cctcttaagt agattttggt tcgttaccat gtctacttaa gagaggtctt caaagtgctt
     1141 taaaacgctg atataacagt atattaacgt tttgagaatt gtgaagcttt acgagctttt
     1201 ttaagacctg gtttttggtt gatattctga tatacataaa gatacttata aaatcaacct
     1261 attcctggtt caatcaatca aaatctatta attatataca aatatcttat tcccaacggt
     1321 atcaataagg tatcaaaaat aagtttcgga gcttatcaaa taatgaaaat ctgtctcaat
     1381 taccgagtct tttttattga cttttttgta tatatgatat aattaaataa attacataaa
     1441 ggggttacat aaaatgacta cagtaaaaaa aaacagagcg gttacctttc aagctaataa
     1501 agaattggta agcgaagcaa tgacagtatt aaacaaaaaa aatttaacct tatcatctgc
     1561 tttaagatta ttcctacaaa atgtcgttgt cacaaacgag gttgacttat tgacggaaga
     1621 ggagttagag aaagaaaaac ttttcaaaca atttcaagct gaaatcaaca aaaatattga
     1681 ggatgttcgt caagggaagt tttatacctc tgaagaagtg agggctgaac ttggactata
     1741 agaaatatca gattatctat gctcctgatg ttttagagaa gctaaaagaa attcgtgatt
     1801 atatttctca aaactactcc tcaacatcag gtcagcgtaa aatggagcaa atcattagcg
     1861 acatagaaaa actcgaggtt ttcccagaag ttggttttga tgccgatgaa aaatatggtt
     1921 caaaaatcag ccattatcac agcactaaag gttatacctt aagtaaagat tatattgtcc
     1981 tataccatat cgagggggaa gaaaataggg tcgttattga ttacttgctt cctactcaaa
     2041 gcgactatat aaagttattc aaataacaca ttaaaagcct tagcagtctt gctagggctt
     2101 ttttggtaga ttaccaatta actaggagca aaatgagttc gggctgttta gtagatattc
     2161 cacaaagaag ccaaagacta cgaagctagg ctaatctacc ttaaggcttc aggaaacttg
     2221 gaggagttca ccaagccaac tcataaaact tatagcgaga tattcgagaa atggtatcaa
     2281 gcctatcaag atacggtaga gccaaccacg gcttctcgta ctcttgatct gtttcgactt
     2341 cacattctgc cagtcatggg agaattgccc attaacaaaa cctccccttt agactgctag
     2401 aacttcatca ccgataaagc aaagaccttt aagaatatca agcaaatcaa gtcctacact
     2461 gaaaaggtct ttgattttgc tatcaagatg aaactgctca agcataaccc tatggctgaa
     2521 atcattatgc caaagcggta aaagacacga atagaaaact attggacggt tcaagaactt
     2581 caggagtttt tagccatagt acttcagaaa gagccttaca agcactacgc actatttcgg
     2641 ctactagctt atagcggcct taaggaaagg cgagctatgc gctcttaaat gggctaatat
     2701 agactttcag agtgagacac taagcgtcaa taagagccta ggacgattag acggacaggc
     2761 aatcgaaaaa aagcactaaa aatgatttct cagtaagaaa gattaagcta gacagcgaaa
     2821 ctatttctat tctgcaagaa tggaaagcca tcagccaaaa agaaaaggca caactagcag
     2881 ttgcacctct ttcaattgag tctgacttta tatttacata ctgtactaga gaagggagta
     2941 ttgaaccact tcatgcagac tatattaaca atatcttatc aaaggtcatt aagcaacata
     3001 gtcttaaaaa aataagtcct cacggcttca ggcataccca tgcaaccctg atgattgaga
     3061 ttggagttga cccagtaaat acagccaaaa ggttaggaca tgctagtagt caaatgactc
     3121 ttgatacata cagtcatgct actgcagtct gagaggacaa atcaatcaaa caatttacta
     3181 actatctcaa aaataactaa ataaacgtat taaaccaagt caaaagtttt ccgaaacggt
     3241 atcaaaagca aaaaacgaca aaaaaagcac cttgcaagag acttgcaaaa tgcttgtaat
     3301 cgttgatgta aagctgttct taacgttttg agaattgtga agctttacga gctttcttaa
     3361 gacctggttt tttacgttca accatacgtg cgtcacgtgt aagaaggcca gcgcgtttca
     3421 atgaatcgcg gaagtctggg tctacttgaa gaagcgcacg agcgatacca tgacggatcg
     3481 cacctgattg tccaccgtaa ccaccaccaa caacgttaac gaaaacgtcg tatgaacctt
     3541 cagttgatgt aactgcaaaa ggttggttaa tgatcaaacg taggtcagca tgtgggatgt
     3601 attcttctac atcttttttg ttaacagtga ttttaccagt acctggaacc aaacgaacgc
     3661 gtgcaacagc gtttttacga cggccagtac ctgcatattg tgcttgtgcc attatttaat
     3721 gctcctttcc tcttagataa gtcctgagat gtcaagtact tctggttgtt gtgctgcgtg
     3781 agtgtgctca ccgccaacga agactttcaa tttcatacct tgtgcacgtc caagagtgtt
     3841 atgtggaagc atgcctttaa ctgatttttc aatcaagcga actgcgtttt tagagcgaag
     3901 ttcaccagca gtgatcgatt tcaaaccacc tgggtacatt gagtgagtgt agtaaacttt
     3961 atcagtcgct tttttaccag ttaatttaac tttttcagcg ttgataacga taacaaagtc
     4021 acctgtatca gtgtgtggtg tgaaagttgg tttgtttttt ccgcgaagta cgctagcaac
     4081 tactgcagaa agacgtccaa gtggcacatc agttgcgtca acaacgtacc atttgcgttc
     4141 aacttggcct ggtttagcca tgaaagttgt tttgttcatg atttctccta tacgaattcg
     4201 taatatttgt ttacaaggtg atgggtgttc cgtcccatcg aaggtatttg gaaggttccg
     4261 gggcctttca aatggggtaa acaataccgc ctactatgat atcaaactta agaggctcca
     4321 gtcaagtgct ttagctgatt ttattggatt attttttctt tcgatttagg agaatggcag
     4381 agctgctctg ctggtgttaa cgagaatcat cagcttccca aaaaaggtcg tctaaggtct
     4441 tatcaagcac tcgacaaatg gcaatgcaaa gattaatcgt tgggttgtaa tcaccttttt
     4501 caacagccgc aatggtttgt ctggagacgc ctaccaaatc tgctagagct tgttgagaca
     4561 aatctttgcc tgcacgcgct gcttttaatt tgaggttctt cattcatctg cctctttagc
     4621 atccagataa tgacgataga aaatactagc tcccatacta aggagcgtta tgcctaacac
     4681 catcagagtc ccactgccgc cagccttgaa aaagcttccc attttaagcg gtcctgtcat
     4741 catctctctt accgccaagc ctataacgac taagctcatt cctgttgcta tcatccccat
     4801 tagtattcct tgttttccaa agcgcctatc cacaaatgag gaagcaccgt tgaggttaca
     4861 atatgtcgtt tgaactgcca accctcccca taaagccaac gtaaagagga agcttgcaga
     4921 taccagtccc tctgtgaatc ggctaataaa gagtgacagc cagataacca caatcataaa
     4981 ccaaaaccca atagtgtatc ctttgagaag aatctgtttt tggcgttcat catatttggg
     5041 caacttctga tcgtccctta ccttagaatc tagtacttcc ttgctatcta gtctcgtttg
     5101 gagctttttc gctgtcttta gtccccatac caacaatatg agaaagctag tcaatacaaa
     5161 agctgtgcct ccaaataaat aacgttgaaa actggtctta gccagtaatg ttgctactat
     5221 gcacaactag atccatcact actgttatga caatgaaacc ccattgtgac ttagcgagat
     5281 tttgtttgct atcaaacatg attcgtttct cctttaaatc tttatatgac acaatataaa
     5341 ttattttgga tattttgtca aatatatttt acattcttga ttgatttaag cagcaaaaaa
     5401 ggattgagga tttctcttca atccttataa gggattaacg ggaattctgc ccaatcacaa
     5461 aaactgccag ggtgttagga ccaacgtgag ctgagataac tggtcctagt ggcatcataa
     5521 gaacatcgct aatattctca tgcgccagca gctcttctcg taacttttcg gcactaccct
     5581 gatcgcttgt ataagagaca ataaccgtcg aatccgcaat atctttttcc acttgagcca
     5641 ccatttcttt gatggctttt tggcgtcccc gaatttttgc aatgggcacc aatttccctt
     5701 cctcatcaat ccacaaaaga ggtttgatac tggctaaact gcctagaaaa gctgaacctt
     5761 ttgacagacg cccaccacgc atcaaatgaa aaagatcatc tactaagaaa taggtgcgca
     5821 gtcgaggaat cactgcttca acaatatctt tagtctccag taaatttttg ccactatctc
     5881 tggcttctgc tgctaaaatg gttagatagc cttctcctcc tgcagcagcc aaggtatcaa
     5941 caatttcaat cactgcatcg ggataatctt ctcgaacaag atcgcgtgcc attagagcgc
     6001 tttgataggt acccgataaa accgaagaaa aagcaagata aagcagtgct ttgttgttcc
     6061 tagcatgttc acgaaaaacc ttctcaaact ctcccacatt aatctgactg gtttgaggat
     6121 gactgccagc tttcatcttt ttcaaaaggt aatcactact aatacggtta ggaccgaccg
     6181 tttcataaac ctctccatcg cacaaaatcg ttaatcctat aaggacaata tcatgatctt
     6241 ctgcccaggt ttgattcaaa tcagcggttg aatctgtcat tattgtaaag gtcattctta
     6301 cttctcctca tccagttttt tagtttgata atcaaataat tattgtttta ttttatcaaa
     6361 aaaacccgca cttggcgagt cgtaattctc attatcgatc taactgagac ataaaatcct
     6421 tcaattgaat aagctgtcct tggtcaaaag gccgcagttt aggcgttttg agatcaatat
     6481 ctctagacat tttatctaaa tcagctttga cagtatgaac tctttgctct aattctcttg
     6541 cagtgacacg aagagctcct tgagaaaaaa tcgtccattg ttcatttaaa tcactcgtag
     6601 ctacttctac catatgtata gccgtattta actctgctgc catgcgctca atgtagctat
     6661 ctgctgtttc gtcttcctct gtaaatacca ctgagatata atactggtca tatcgttgcc
     6721 ttaaccccgg tacatattgg gcatcaaaaa cacaaataat attaatattc tcaaaatggg
     6781 cataatgatt aagttttgtt aaaagtgtgt tacgtgcctg atcaagctga tttgtcttaa
     6841 acaactgacg ggttgattgc caaaaggcaa tcatattata cccatctact aataatatcc
     6901 gttttttcat aatttagcgc ctatttcgga aaacttcata catgagaata gctgccgcta
     6961 cgctagcatt taagctctgt acgtgaccat tcataggaat cgtaatcatt tcatcaactt
     7021 gctttttgat attggtagag atacctttgc cttcgttacc aatgactaaa gcaagtttac
     7081 cattagtgtt ccagcaatca gacggtgttc cattcatgtc tgtgccaaaa atccagaatc
     7141 ctcttgcttt caatttatct agagtttgac taaggttagt tactctcgct atcggaatat
     7201 gttcaacagc acctgtagat gtctttgaaa ccactggagt cacaccaaca gaacgatgtt
     7261 taggaataat cactccacat acatttgtag catcagctgt ccgtaaaatc gatcctaaat
     7321 tatgaggatc tgtcagacca tctaaaataa gaatcaaagg atttgcttct tgctctgcta
     7381 tttcgaggat atcatcaaca tcagtatagg caaaagctga tactctcaga acaaaacctt
     7441 gatgcacagc tccatcagtc atttgtgaca aggttttttt aggcgtccat gaaatagcga
     7501 cctttttttg tgtcgctaag cttttgatgt tatccacttt ctttcctctt aaatcctctt
     7561 ggatataaag cttatttcct gtatttgctt gaaggctttc tgtaacggca tgaacaccat
     7621 agacgatatc gtttgtttca atagtatctt tatcttccat gagtttatta taccatgaat
     7681 gcttcaaaat aaatgcatag actcttttat tttcgtctag atactttttg aatagctata
     7741 aataaacctg cagctaaact gactactaga cctgataaga cccaagggaa tcctcttttt
     7801 gaagtaggtt ttacttcctc tttgtccact agcatttttg tcttgttgct accgtttttt
     7861 tggctattac tagcagttgg tgtaagtttc tcatttttag tagatcgctt taaggaagtt
     7921 gatcgatgat tagtagctga tttgaaagga tttgaagtag aatctatttc ttggttagct
     7981 gattgatttg tttgagcttt tgtgtctaca tcgaccgaat tcgtcgttgc tttagaagta
     8041 tccttttgtt gcatattagt tggtgttttt ctagctttgt tttgatcaaa atgaacagtt
     8101 cctgattgac cagttactgc cttttcttga gtatgaacgg tgacagttac atgatagtca
     8161 ccactctttt gtccagttaa atcaaaccaa gctgtaaaac gacgctgttg cgctaccata
     8221 gtatataccc aactattaat agtattatca ctagcgtctt taagtgttat cgttgcctga
     8281 gttggttgtc tgacaggttg atctgtggtg actgtagcat caatataagg ttctgttcca
     8341 cgcatactgg cttcaacact gacctgacta atagttgatt cagctataac attatcagtg
     8401 tgctgatctt gtgcatacac agatatggct ttgccagaag tccccagcaa accaataagt
     8461 aaagctagtg ataataagct aactgttttt tgcatagttg tcataataaa tatctcctct
     8521 ttaaattagt cttacccttt cattataaac tattcgaaaa tgatttcatt atttttatgt
     8581 cttttttgtt acaaatgtat cttttttata tcattatgtc tttttgatgt cacaaaaaga
     8641 cttaatggct ctctaccttt acttcagatc tatgaaaata agagtctcct aggggactct
     8701 tatgaggata tcaattgttg cttttctaca tactcaatac accatctgat caattcttct
     8761 aaccgctctt tttggcccat catatcaaga taacccataa tggcttcaaa acctgtcgac
     8821 atacgatagg taataatatc ggcattctta gctttagtat ggctattggt attgcgacca
     8881 cgcttataga tgtcttcttc tttttcggtc aatagctgcg cttctaacat agcctgaatc
     8941 aagttggctt gtgccttagc agaaacatat ctcgttgcta aacggtgtag ctggctaggt
     9001 ttcgttttac cttgaaaaat gagatgacga cgaacatagt aggaataaac cgcatcccct
     9061 tcaaaggcta gggcaatgcc attaatcaaa ttaacatcaa ctggattagt cacgcagcca
     9121 cctcacacca tctttggtat ctagcagctt gatgccttga gctgctaact gatctcgaat
     9181 ggcatcagct atggcaaaat cacgattcgc gcgtgcttct tgtcgcttag caatcaaggc
     9241 ttcaatgtca acctcaagca cctcttcttc aaagataatg ccaaaaacag ctaacatttt
     9301 ctcaaaagcg cttttaacag gttctgtata ggagccagaa ttaatccact tagccatgtc
     9361 aaatacgacg gtaatcccat ttgctgtatt gaaatcatcg tccatagcgt cttggaaagc
     9421 tattacaaac tgttttagct cttgctcatc tgcagtttct gtcagcggtt gttgcaaggt
     9481 gtttttaaga tacttcagat tgatttccgc atcatgaata gccttttcag tgaagttaat
     9541 tggttttcgg tactgttgtg tcgcaagaaa gaatcgcaaa acctgaccat caacggtttg
     9601 taacatgtca tgaacggtca caaaattacc tagtgacttg gacatttttt cgttatcaac
     9661 agtgacaaac ccattgtgca tccaatagtt agcaaaagtc ttgcctgttt tagcctcaga
     9721 ttgggcaatt tcattggtat gatgaggaaa ttccaaatca gctccgccac catgaatatc
     9781 aatggtatca ccaagaattt cagtagccat cacagaacat tcaatgtgcc agcctggacg
     9841 accaaacccc caggggctat cccaagaaac ctcacctgcc ttagctgatt tccaaagagc
     9901 aaagtccagt ggattttctt ttaaagctgt ctcagcatct gttcgaccac tggctccaac
     9961 ttcaagttct gacagggttt tattagctag cttggcataa tgctctgact tttccacgcg
    10021 gaaatacaca tctccatctg cttcgtaagc aaaatctttt tcaatgaggc tttcaacaaa
    10081 tgaaatgatt tctgctatat aatccataac acgaggattt tgtgtggctg gcttaacacc
    10141 aagtgccttg gtatcttcta taaaagctgc aataaagcga tctgacaatt ctttaggaga
    10201 aacacctgct tgagtagcag ccttgataat tttatcatcg acatcggtaa aattggaaat
    10261 gtaattgacc tgatagccag tatactcaaa ataacgtcga atggtgtcaa aagcgaccgc
    10321 tgatctagca tttccaatat gaatataatt atagaccgtc ggtccacaaa cgtacatatt
    10381 gactgtattt tcagtcaaag gtacaaactt gcggagcgaa cgggtcatgg tatcataaat
    10441 tttaatcatg taaactcctt attcaatatc ctagcattag ttgtcatctt gatatcctaa
    10501 gtctttttct gaaatgctat tccacctttt caacaattta atattaataa ccaaacctat
    10561 taaccaaaat agggtcaaaa tgaagtatat aatcgcttta accatgtctt gtctcagtaa
    10621 aaagattaga ctagccacca gtgtaatact agaaacaaga atagacaaac tcataatgac
    10681 atacagccca actcttattt tattcatgag gctcctttat taacgaaaaa ccttcacaac
    10741 ctgtgaaggc ttcagaaagt agacaaaccc acttttatgc tcaaaaagca tgaatagatc
    10801 tgctgatttg acatcaggtt tcctatttct gcatgtgggg tgagccaaaa cagctgcttt
    10861 ttgttgtggt aaaagtggta tcaatactga cagtgatgcc catacagatt tttgagacct
    10921 taggctcaaa actaaggcat ggaattccaa aggaagtcgc tgccgtaagc accacctgag
    10981 aaaaagtatc acaatagact gtttcttcag tctaagactt gcttagttga tgctctttta
    11041 cgtgtttttt gtattttgta acattcccat atcactacac tcagcaacca aactgatagg
    11101 gctagctaag ttcaacatta ctctactaga aagtcccaaa atattttatc ggaagtcatc
    11161 agtgcttctt tttgttattt tccgatcatt ttgacaactg ataagagacc tctcgttgtt
    11221 tttgtaaact ttgaatttga cgattatctt tttgcccatg cactcgtact atcttagctg
    11281 gcacacctac aactgtcacg tcttcaggaa catctgataa cacaacagct gctgccccta
    11341 ctttagcatt tgctccgatg tcaataggtc caatcacttg ggcatgtgcc gaaattaagg
    11401 caccttgtcg aaccgttgga tgacgcttgc cacaatcttt tccggttcca cctagggtca
    11461 ccccatgata aagcatcaca cctttttcaa caattgctgt ctctccaata acaagaccag
    11521 caccatggtc aatgaagact ccaggagcga tttgtgctcc aggatggatt tcaatttgtg
    11581 tccaaaatcg ccaaaattgg ctatgcattc tggctagtaa tttaaaatga tgtcgccaaa
    11641 gaaaatgaga caaacgatga gcagctaggg ctttgatgcc tggataagtt aggataacct
    11701 caagactatt acgagcagct gggtctagag ctttaacaat agctatactt tctttccacc
    11761 aacccatact aactcctacg acttatctaa ttctgaccaa tcaacaagaa tttgttggtc
    11821 atcaaaagga ttgatggcga caccgaacgt ttcatcaagc tcgttttcac catttcttgg
    11881 ttgataaata tcatcaatcg tccaagtcag aatcactcct tcagctttcc tgaaaaggcc
    11941 tccaaaatcg tcttggttgt accatttcgc aaagctttga agatttgaaa aggcgggaac
    12001 atagcttttt ccttcaggcg ttgacatggt aggaaaaagg cggtcgtaat ggttatcatc
    12061 tttaggataa acaaaggcag gaacaaggta aaccttttcc atcgtatctg ccgccacatt
    12121 gtcatcactc ataagcgtat ttaacacagt ggtgtaatgg ttcataaatt gaatcatgtc
    12181 actgcttttg aaaatggtag aattcccaaa atctcccttt ttcttaaggt taaagacaag
    12241 acctgctgca ccagatgtaa tgacttcttc tagcactgca agagctgaac gctccagcca
    12301 atactgactt tgagcactct tttgttcttc tttaaagcga gccatatctt ccttatcggt
    12361 aaaaacaggg gtaaccttga caccttcgac ttctatcacg tagggttctt tagcagccca
    12421 gacaggaaaa ttatggaaag cgttgacaag cgcaaggcta tccaaaaagt tatcaggcgc
    12481 attgataaaa gctcttaagc gaatatctaa ttcatttgat ttagtcatgt ttttcttctt
    12541 ttttctctgg ttttggtggg cgtggaatca aagctttcat tgaggcatcc acacgaccct
    12601 tctcatcaat cttaatgacc ttaacatcaa cgtcttcacc cacttcaagg acatctgaca
    12661 cgttggtcgt tctagtccaa gcaatttcag aaatgtgaac aagtgcatct gtcttgtcaa
    12721 agaggttgac aaaggcacca aatttctcaa tacggacaac cttagcatgg taaacttcgc
    12781 ctaccttagc ttcacgtact aggccagcga tgatttcttt agtgcggtta atggcagctt
    12841 ggtcacttga gtagatagag acatttcctt cgtcatcaat atcaattttg acacccgttt
    12901 cggcaataat cttatcaatg gtttcgccac ctttaccgat aaccactttg attttgtcta
    12961 cgtcaatctt gatggtgtca attttcggtg cagttggggc taactcggga cgtggttcag
    13021 cgatagttgc ttcaatcaca tcaaggattt caaagcgagc ttttttagct tgtgcaagag
    13081 cttcttctag gatttgaggc gtaatccctg caatcttaat atccatttga agggctgtaa
    13141 tcccttcacg agttcctgcc actttaaagt ccatatctcc aaagtggtct tcaagacctt
    13201 ggatatcggt caagactgta taattcgtcc cgtctgaaat gagacccatg gcaatccctg
    13261 ccacaggagc cttgattggt acaccaccag ccatcagagc aagggtacca gcacagatag
    13321 aagcctgaga agacgaaccg ttagattcta gaacttcggc aactaaacga atggcataag
    13381 gaaactcttc taagcttggc aagacttgtt caagagcgcg ttcacctaag gcaccgtgtc
    13441 caatttcacg acgaccagca gctccgtaac gacccgtttc accaactgaa tattgcggga
    13501 aattgtagtg atgcaagaag cgttttttgt actctggggc cagaccatca atgatttgag
    13561 tttctcccat tggtgccaag gtcaaaattg atagcgcctg agtttgaccg cgcgtaaaaa
    13621 gacctgatcc atggaccttt ggcaagaagt caaccacagc atcaagcgga cgaatttcgt
    13681 caatcttacg accgtcagga cgaatcttgt cctctgtaat gaggcggcgc acttcagcat
    13741 gctccatttg ttcaaggatt tctgccacgt cacgcataat ggttgctagg ttttcgtctt
    13801 ctgcgtaacg ctcttcgtac tcagccttaa ccatttcttt aacggcttct gtggctgctt
    13861 cacgcgcttt tttctcttca acttgaacag ctttttgcag ttgagcattg tacttagcta
    13921 caatatcaac ttgtaagtct gcatcaacct gtaacagttc aacctcagct ttttctttac
    13981 caacaacggc tacgatttgt tcttggaagg caattaattc ttgaatagct tggtgacctt
    14041 ttaaaagagc ctcaagcatg atgtcttctg ataattcttt ggcaccagac tcaaccatat
    14101 tgatggcttc tttgctacca gcaacggtta attctaagag cgacgcttcc atttgttctt
    14161 tatctgggtt gatgatgaac tcgccatcaa tatagcaaac ttgaacacct gcaatcggtc
    14221 cattaaatgg aatatctgag atggacaagg ccagagatga gccaaacatc gctgccattg
    14281 gagcgctagc attttcatca taagaaagga cagtgttaat cacttgtact tcgttacgaa
    14341 aaccctcggc aaacatggga cgaatcgggc ggtcaatcaa gcgagctgtc aaggtcgcat
    14401 ctgttgaagg gcgtccctca cgtttcatga aacctcctgg gaatttacca gcagcataca
    14461 ttttttcttc gtaattaact tgaagaggga agaaatcacc cgttgccatt ttcttagaca
    14521 taacagctgc ggttaggaca gttgagtcgc cataacgaac aacggttgcc ccattggctt
    14581 gcttagcgac ttgaccaaca tcaacaacaa ggggtttccc tgcaaatgtt gttgtaaagg
    14641 tttgttttga catatattct ccttttaatt ttcagagggg taaagaggta cctgttctct
    14701 gcttagattc aattgttata cgttgttttg ctacaaaaag caacctgcca cgcttgtcac
    14761 acgctcctct ttgtatcaaa cgacgtatct gctacatttt accataaaat agcagaaatt
    14821 tcactgtcag atcgcaatct cttgaaatgt ccttgaaaaa tattaaacga aacttatact
    14881 ctttaacaaa gcaaaaaaag caggttggta tgcctgcttt cgtctcctaa tattaatgat
    14941 tgtcatcctc taaaatttta aagccgaggc tggtactgtc tttcagaaac atttgcacgg
    15001 tttcaaggga atagtcttct aaatcttttc cttgaagagg cagcttggca atcaaatcag
    15061 tggtacaagt gataatgtcc acgcctagct gatcagcttg atagatatta taagtttcac
    15121 gaggactagc ccacaacaat tcgacctctt ctttttgacg acaaatgcgt agagcttctt
    15181 ccatgattgg cattgggtca acgccggtat ctgcaatacg accagcaaaa acagacacaa
    15241 tagctggaac tcgagcggtt aaatgatcaa ccacagcttg agtctgctca attgtaaaaa
    15301 tggctgtgac gtttaactta atgcctttgg ctgacaactt ttgaatgagg ggacaggttg
    15361 attctcctgt tgaagtggtg actggaattt tcacatagac attgtcacct agactggcaa
    15421 ttttctcagc ttccttttcc atacttgcga gatcatccgc aaagacttca aaggacactg
    15481 ggtagtctgt aattttggca agcacttctt tggcaaagcc aatataagaa ctgatgcctg
    15541 cttttttcat caaacttgga ttggttgtaa agcctgtgac caaacctgtt tgtaaatcct
    15601 ttaacatggt ctctaagacc gcaccgtctg aaaagacttt aacgtttagt ttttttgtca
    15661 tcatgtcctc cttttagatt tcttctgaaa cattattgat ggcctcttga gattttgaca
    15721 gaaagcttgg aagcaccaat acaatagcaa gcacagcaac caccaagtaa ataccgattt
    15781 gaccaatcga cgttcctaag cggcccagta aaatccctaa aacaccgaaa tccacatctc
    15841 caaaggtcgt gtttgaaaaa ccaagtttcc caagtacagg tagaagcatg gcaggcaaga
    15901 aggcgagtaa taagccatta gcgaaagcac caatcatcgc accgcgacga ccccctgttg
    15961 aatttccaaa aatccctgct gttgcaccgc agaagaaatg aggcaccata cctgggataa
    16021 tcaggacacc acctgcaact cctaaaatca acatcccaag taagccacca acgaaacttg
    16081 acgcaaaacc gatgataaca gcggttggcg cataagggaa gaataccgca cagtctacag
    16141 ctggaatagc atttggaatt aatttgttag caataccttg gaaggctgga atcaagtcag
    16201 ccaaaatcat gcgaacaccg gcgtagacaa ttgccacacc aaccgcaaag gtaagaccac
    16261 tcttaatggc aaaaataaat gggttttgac ctgctgctaa ttcttctgct actgaagcat
    16321 ccctcaaaac agaagccact gttgccacca agtagaaaat caccatgata agtcctgttg
    16381 aaatggtggt gttgcgtaag aaactccatt tttcagaaat ctgaaggtcc tcggtatctt
    16441 tactgtcttt gccaaccttg ctactaaccc aggcagaaag gtaatagccc aaactaccaa
    16501 agtgtcccat ggcgatttca tctccgtcag tcactttcag agtatactgt tgaccaatgg
    16561 ctggcgaaat agctgaccaa gctcccaaga ggaacccacc taagataatc aaaagacttc
    16621 ctttgaaacc aacagctcca agcacggcgg acaagagaca agccataaag aagctgtgat
    16681 gtcctgttaa gaaaatgtat ttgaagcggg taaaacgagc aaaagccaaa ttaagcaata
    16741 acccaaccac caagatggac atagtttcca cacccagaat cttttgagcg acagaagtga
    16801 cggcttcatt atttggcact acgccagtga tgctaaaacc gtgctcaatg agtttggcaa
    16861 gagggtccag attggtcaca ataacacccg cccctgcagc aagcataagg tatcccaaaa
    16921 tcggccccaa ggttcctgtc aacaccttat gagcaggtgt tttcaaagcc accaaccctg
    16981 caaaggcaat caagcccatt aaaaatgcag gttcttttaa aatatctcga ataaatgata
    17041 ataatgcttc catagtatct tcctatctcc tttaaaaagg cttatccctt gccactcatt
    17101 tccttgagaa ccggaaccaa atcttcttca atttttttac gattggtata gcttttaacg
    17161 atacaaacct tggcatcctc tggaaaaata tctttaaatt ctttaacggt aacaaataaa
    17221 tctgcaccct ttccaacagc cgcattggaa tcacaggatt ctgcatccac atcaataccc
    17281 aaactagatg cgatagcttc gactttcata cgaagtaaca agctactacc aataccgttt
    17341 ccacaaaccg ttacaatttt aatcatgtga ttcatctcct ttttcaatca tatggctaat
    17401 cagactcatt atttcctcag tattcttagc ctcaattaat tgctcaatat gttcatcgtc
    17461 atctaaaatc aacgacagtt cctgcaaagc cttcaaatgt gaactagaat ccacagcaga
    17521 caaaacaaaa atcaattgca cttgcttgtc tggatcacct tcttgcttca aatcaaagct
    17581 gacaggttct tttagttgta agagagacat gcctaactgc cgcgttcctt tttcaggcgc
    17641 cgcatgagga acagccacct taggggctaa aacaatatag gccccaagct cattgaccga
    17701 atcaatcatg ccatcgatat aagatgtttc aatcatctgg tgttctagta aaggctgagc
    17761 agccaaacga atcgcttcct gccaatccga aacagcatca gcctgcctaa taaaatctgc
    17821 tgttaacaag tccaatagtc ctagacctcc tttttcaatc gttaaatggt taccaatcag
    17881 gtaacgggat aaatcactaa caagtccttc tttattagta atcgtggtgt gtttatgaat
    17941 aatactcaac agatcatcca aagcgaattg ctctgacaag ggaagatgaa agtcatcaca
    18001 gaccatcttt ttcaacatca ttttttcaac aggtcccatc aaagcttgcg tcacataaac
    18061 aggtttagca cagtcaaaag ctactgttga aaaaatcaaa tcaaaggaag ctggatccaa
    18121 caactttatt ttgtccagct ggtgaatcct aataaactgt agctgtggaa aaagttcctt
    18181 caaggttgcc tccaacatca gagacgaact gatgccatta gggcaaacag ataaggctac
    18241 cagctgattg ctcggcctct tcttaggggc ctgcaaccat ctcccaaaat gaatggtaaa
    18301 ataagcaacc tcatcttcat taactggttt ccccaattgt ttttctagag gagaaaggct
    18361 gcgcttgacc aagtaaaaga gagattcata atcttgtttg atttgttcct tcaaaggatt
    18421 ggtcaagtta atgtcgtagt aaagtcggta ataagctggc aaaaggtgac tgtataggtt
    18481 ctgacgaagt tctggggtat cggtgataga caatcccgtg ttaaccgcca ccgaattgat
    18541 gatttcctcc ataatgtcat aaataggttg ctgaaagact aactctaagt caccttggat
    18601 acaaccaagt aacctagatt gaaccaaata tttttcttcg gttagactgg ggaagttgac
    18661 caataactgg tccaccatcg tttcaacagc tggcgaagct aaaggaaaag tatccactgc
    18721 ttcagccctt acattccgtg aaaatggtcg atgagcgaga aggcagaaaa aataaatcaa
    18781 atccctcaat ttctccgaaa taaaagttaa gtggttctcc ctgctcagtt cctccaacgt
    18841 tgctgccatc acctttgtct ggtcgggcaa accaagttca tgcaataagt aactgaacac
    18901 ccaaggtcct gatgtaactt gcaaaagaga actgaccgct gattctaaga gacgccgcaa
    18961 ggctaagggt tctccttcaa aaaaataacc atcctggcga ttgtaagcta aagttacctg
    19021 aaaagcttgt acccgatcac gcaccaagtt taaatcagca ataacggaat ttctgctgag
    19081 ccgtaacaag ctttccaagt ggttaatgga gataaattct ttagccatca tgatgtaaat
    19141 aataatcatg tccagacgct catcttgaaa gagatagtcg tctaaggtag gtagtatgcg
    19201 attcaacaag tccttttcag taaggtctgg cggataaacc agctgcctgt ccagagcaat
    19261 aaggggtaac tgatagagtg acaacgtgtc attgatttta gcaatatctg ccagtatatg
    19321 acgtttgctt gtctttaata tggattcaaa tgcctccagt gaatgtcctt tatatttaga
    19381 aaagagttga tagtttctga tgagctcatg agatagcatg tcatctcctc ctataatgtc
    19441 agtataaaat gaagcgtttt cattttcaag acaaattgag tccaattgtc tctcgtcatt
    19501 tttgactgca attggactca acaggtgata tcattgtaac aagttcctca aaaggtggca
    19561 aaaaataggc aaatctggga attgattccc tttttcttca tgatacaaca aaagatacct
    19621 catcactgag ataccttttg ttgctaaata aaatcatcaa ctgctaacca aaacagcctt
    19681 agaccattct agccaaatgt gtaaactaac aaacaacatg tcaaaaatga aaaagcctac
    19741 tgcataagca gaggactttt taaacttgaa attaacgacg aagtccaaga gattggatca
    19801 actcacggta acggttaaca tctgtacgac gtaggtatgc caacaagtta cgacggtgac
    19861 caattttttt catcaatcca cggtaagtag cgtggtcttt tttgtgttct ttgatgtggc
    19921 tgttcaagtg gttgatttcc catgtaagaa ctgcaacttg aacttctact gaaccagtat
    19981 cgccttcgtg acgtgcatat tgagcaatga tttcattttt tttctctttt gagattgcca
    20041 taatatattc tccttttttt gcttaatccg agtcttagga ttggcactcc taaaaccaag
    20101 aaaaagttgg tttgtctttc gaccactcta ttctagcaga ttcataatat taggtcaacc
    20161 gttatcctat tattctgagc tctcacatcc aaaccacctc actaggctta aaaaggttat
    20221 ctggtcgttg aatgtgctct ttttgcttta accaaaccac cataagcaac agaactagca
    20281 aggccaaata gccaataggc tgtttttaaa tcagaataaa cctgcgcgat tgcttgccta
    20341 ataagataac caactaaaag aggtaagatg gctgatccca gcacttcagc tgataagcgg
    20401 tagcctagca tagtcattca tttctttcca acaaagtgtt cactgataat atgaattgct
    20461 ctagtattaa caaacccaat ccctaatcca tgaacacagc ttattaaccg atgcgacctg
    20521 cctttatgac ataggtcaag agttgacaca aaatgtttgc caacaaaaca ttacctatac
    20581 cgtcaaagag cgctttgctt cctataccct tgaagcgcaa gccaaccaag aggttcatct
    20641 aaaccttaca ttattagcaa accgttttgg aacaagtgat cgccatctta agcacgtact
    20701 taagcagccc atttttcaga ggattatcga acacatctgc ttcaaaacct atcgtattgc
    20761 cgatttagac gctctaactc aattaagacc tctgaggtat gcagcccatt aacttataat
    20821 agcaatcact ctaaccacta tctgactttt ctttaaaaaa gaaatgattt gtgatatagt
    20881 aaatccagtt aaaaaaaagt aaaggagtag acatgtctgc acaagataaa ttaattaaac
    20941 ctagtcatct gattaccatg gatgacatta ttcgtgaagg gaatccaact ttaagagctg
    21001 tcgccaaaga agtgagctta cccttgtgtg atgaggatat cctattagga gaaaagatga
    21061 tgcaattttt gaagcattct caagatcctg taatggcgga aaaacttgga cttagggccg
    21121 gtgttggtct agcagctcct cagattgatg tgtcaaaacg tatcatcgct gtgctcgttc
    21181 ctaatcttcc tgataaagaa ggaaatcctc ctaaagaagc ctatagctgg caagaagtcc
    21241 tgtataatcc taaaatcgtt tctcattctg ttcaagatgc agccctttct gatggcgaag
    21301 gttgtttatc tgtcgatcgt gttgttgaag ggtatgtggt tcgccatgct cgtgttacag
    21361 tagactacta tgataaagaa ggacaacagc atcgcatcaa attaaaggga tacaacgcta
    21421 ttgtggttca acatgaaatt gaccatatca atggtgtttt gttctacgat cggatcaatg
    21481 ctaaaaaccc ctttgaaacc aaagaagagc tcttgatttt agactaacaa aaaaaggccc
    21541 tttagccttt ttttgttagt ctaaatagcc gctaaaagag cctctgcctg agatagcaag
    21601 tttgcttttg tctcttttga aatctcaagc cttcctgttc cccaggcatc aggattcaca
    21661 gttgcttttg taaactctcc tgctactgaa gttcggataa acggcaatag tgctttaaac
    21721 tgatcaaata cttgatcatg cccgccattt gcaactgaag agaccgtaac caccttaccg
    21781 ccaatagcag atgggcccgt cggatcagac aaatcaagag cacgagacaa ccagtctagc
    21841 aggtttttaa cagaacctgg aatagagaag ttgtaaactg gtgtaaaaat ccagatagca
    21901 tccgctgact gaacagcttg acgagcgtca acaactggta aaggtgcatt agcttcgata
    21961 tcttgattca aaacaggaac gtctttccaa tttaagtaag atacaactgc ttgatgttcc
    22021 agagcttttt gtgcttgagc cgctaattga tggttaaaag acccttcacg aagcgagcca
    22081 acaataaata aaatatgttt catctctttg tcctcttttt taaagatcgt tttaaagctt
    22141 tctaaaagtg gtatttcatt gatacttctt tttgaaattt atcactatgt agtaattata
    22201 tcttctctaa gaagagctgt aaagagattt gtttataatt gtttgaactt tttgagaagt
    22261 tcaatcagac aaagttgttc tttttcagtc aaaacagcaa aggcttcttc cacccgtgcg
    22321 acatgtttag gcaaaacagc ttcaatcaag cgagtcccct tatctgttaa ggtaaccaca
    22381 taggctcttt tatccgtttt gtctttgcac ttgctaatcc agccattacg ttccatatta
    22441 tttagtacaa cagtcatatt ccccgaagtt gctaacaaag aatcaatcaa gtgattgatt
    22501 cgcatacagc ctttagtata tagtacttca agcacactga actgcgtggc tgttaaatct
    22561 gcctttttaa aaatatcagc cccaaaagca tctagcgttc gctgagcttt acgaaacacc
    22621 accatggctt tcaaagcggt gttcttatct aaatgactca tttgatttcc tcgctttata
    22681 cggtatgtca cagtttagta tcagagagat tagaaagtga tcttgtccct cttcttttat
    22741 gactttgcat atgactacca tcatgataat ctagaaaaag tcatcaaaaa gacttaattg
    22801 attatcttct ggcatatttc ctaaaatacc catctcatcc attttctcaa cgagcgttga
    22861 cgatgccccg cctcgtttac gcaattccat tttagagagg aattcgcctt cttgacgagc
    22921 tttaacgatt tgcttggcca cgttttcacc cagaccttct aacgctataa atggagggat
    22981 aagggtatct cctttgattt ggaattctat agcatcactt ttgtaaaggt ctaatttgcc
    23041 aaacttaaag ccgcgttcta acatttcgtt gacaatctcc aaggttgtaa agaggtcatt
    23101 ttccacattg gtggcttcat tatttttacg ttttatagta atatcttcca ttcttgcttt
    23161 aacagcatct aaaccaccac tcatggtttt taattcaaaa gccttcgcac gaatagagaa
    23221 ataagcacaa taatacataa tggggtggtg caccttgaaa taagccaccc gaagggccat
    23281 caaaacataa gctgccgcat gggctttagg gaacatgtac ttgatttttc cacacgattc
    23341 aatgtaccag tcgggcacat tgttttctcg catggcatca atatagccat tacgttcttc
    23401 ctcagaaatt tttagccata atcccttacg cacacgctcc ataatggtaa aggccatttt
    23461 tggttctaag cctgcgtgca tgaggtaaac catgatgtcg tcacgacaac cgataacggt
    23521 ttttagggtt gcaatgcctt ctttaatcaa atcttgtgca ttaccaagcc aaacatcggt
    23581 tccatgagat agtccagaca actgcaaaag ctccgcaaaa gtggtcggat gcgtctcatt
    23641 aaccatgccg cgaacaaagt tggttccaaa ttctggaatg cctagcatac cagtcggtgt
    23701 cccaatttgt tccggggtaa cgcccaaaac ctctgtccca gaaaagagag ccataactcc
    23761 cggatcatca gcaggaatag taataggatc aatgcccgat aaatcctgaa gtttacgaat
    23821 catggtcgga tcatcatgcc ctaggatatc aagtttcaag acgttttcat caatatcatg
    23881 gaagttaaag tgagttgtct gccaagaagc cgttacatca tcggctggat attgcacggg
    23941 ggtaaaatca taaacatcca tgtaattagg aataacaaca atccccccag ggtgctgccc
    24001 agtcgttcgt ttcacaccag cagcacctgc tgctagacga tccacctcag catcccgata
    24061 gaacttgcca tagtcgcgtt catagccttt gacaaatcca taagctgttt tttctgctac
    24121 ggtaccaact gttccagcac gaaaggcgta ttcgtcacca aaaatatctc ggacatccaa
    24181 atgggcactg ggttggtcat caccagagaa gttcaaatca atatcgggca ccttatcccc
    24241 atcaaaccca agaaaggtct caaagggaat gtcttgccca tctttttgat aaggggtgcc
    24301 acatttcgga cagggtttat taggcaaatc atagccagat ccaactgacc catctgtgat
    24361 aaattcagaa tgttggcagg acgggcaaac gtagtgaggc ggcataggat taacctcagt
    24421 aatcccaatc atggtggcga caaagctaga ccctacagat cccctagaac caactaggta
    24481 gcctcgctca tttgaccggt taacaagcat ttgggaagcg agataaatca cagcaaaacc
    24541 gttccccaag atagaggtta actctttttc aatgcgtaaa tcaataatat ctgggagagg
    24601 attaccataa atttcaaagg ctttttgata ggttaattcg gcaaccgtct cttcggcctt
    24661 atcaatatac ggggtgtaaa gatcgccctt aaccacttcc acttcctcaa tacggtccgc
    24721 aaaatcctga gtattttgca caaccacttg ataagcgagg tcttttccaa gaaaggcaaa
    24781 ctcatccagc atttcattgg ttgttctaaa gtgcgcttta ggtagaggag caggttgggc
    24841 cccttcccca cggccgattg ttctattaat catggcaccc tgaccgagac tacgcacaat
    24901 aatttcacgg taaatctctt cttcaggctc tagataatgc acattcccag tggcaagcac
    24961 aggtttctta gctcgcttcc ctacttcaat gaggtcacga atcacctgct caatacctgc
    25021 ttggtctttg attaattcac ggacaaccaa tggctggtaa atggctggtg gcatgatttc
    25081 gataaaatca taatacttag ctaaatcaac cgccgcatca attcctttag tcagaacggc
    25141 atcaaaaacc tcgccgtcag aacaagctgt acctagtaac aaaccctctc tgtgagcatc
    25201 taagacggtt cttggaatac gcggcacccc ttcaaaatat ttgatattgg aaaggctgac
    25261 cagcttaaac atatttttaa gaccaacctg attttgcaca tagatagtcg catgcttaat
    25321 tcgcgctttt ttgtaagaat cctcagctac caaatctgta ttgagttgca aaagattttt
    25381 gatgccatgc ttttctctgg catcttttag aaaaataaac aaaagacgtc ctgtggcttc
    25441 cgcgtcgtaa ttggccatat gatggtggtc tagactcact tggaaacgct tggtgagtgg
    25501 tcccaagccg tgacgcttgt attcaggata caaatttctt gcgaattcta aggtatcaat
    25561 cacaggctgt gtgattttgg gcaagtcatg gcgttcataa ttggcgttca taaagcccac
    25621 gtcaaaactg gcgttgtgag caactaaaat actatctttg caaaagtcct gaaaagcttt
    25681 taggacggta accaatggct tggcgccctg caaatgctta tcggtaatcc ctgtcaattc
    25741 ggtggtaaag gcagaaagag gatgtccagg atcaatgaat tcatcaaact gctctacaat
    25801 atttccttta aacattttgg aagccgcaat ctgaatcagg tcattattca tagcagatag
    25861 acctgtggtt tcaacgtcaa agaccacata ggtagcttcg tgcaaatcca tatcaacagg
    25921 atcataagaa ataggcacct tgtcctcaac aatattggct tctaggccaa aaatagcctt
    25981 aatcccggcc ttacgggctc tatggtagcc atgaggaaaa ctttgcacat tagcatggtc
    26041 ggtaatagca accgccttgt gtccccattt agctgccgta tcaatcaagc tttctactgt
    26101 cggtaaggca tccatggtag acatattggt gtgggcatga agttcaaccc gcttttgccc
    26161 ttctggcatc aggtctttgc gctcatgatg gacaatttct ttgacctgct gcacattcat
    26221 ggtgagactc ttcgtaaaag gattggtctc aatattccct tgtacccgta accaagccct
    26281 cttagcaatc atatcaaatt tacggagctc ctcatcgtct ttagcccatt tttggagagc
    26341 aaacgaggag gtatagtctg tcattttaaa gttaatgata tggcgacctg ttctagtcgt
    26401 tttacgctcc acatcaaaaa ccatcccctc aaagacagtc cggttttctt cggtctcaat
    26461 ctcaatcatt ggtgtgatgg tcgctttttc aaaccctgcc tgacgcttag ctgctcgttc
    26521 cttgtagtca aacttaggag caggtgtggc ttcctcaact ggtggcatca tggcttcaag
    26581 agatttttgg gcttccaaat tatcctgcac agcctttttc acaagagcct gacgactgga
    26641 aacaaaattc ttggtcaaat gctcagtcat ctcctgatct gacaccatat ctatggtcaa
    26701 ggtgccaaag ccaaaggctt ctaattgctt gaccagatta ggcagatgat tgtttctaaa
    26761 atgatcgtta ttcacaaaac ctggcgctgc aataatgagt ttgtcattct cataagtcac
    26821 tttgagcttt gagaaagaag atttaaaact agcactatta cacggtgcat gctcaaaagc
    26881 ttcttggtaa taagcttgaa gcagatcatc tgaataatcc acttgagcag cttggatatc
    26941 aaaggttacc ttaatgtcag ccgcctcaaa agttcttatc aaacgatcat gcaattcacg
    27001 ataagttgca atcggtaaaa ccgccgcaaa ggcaaaatga aattcccaca agcgtgacac
    27061 cgaatgcacc tttacctcga taatatcagc agatgaaaag gcacttgaac gtctcatgtc
    27121 aagtggcatt tctatctggt ccatcaattt agcgaataaa tctgacataa ttttctcctg
    27181 attttactag gctttatttt atcacaattc aagatgattt tcgagtttta gatggaaaga
    27241 aaagcagggc tttcttctga cgttctttga ctaatttatt ccaagtgata gctcagttga
    27301 ggtcattttt ttgccaatct tttgtcgcca agcgcttttg gtaaagcaaa agccactctg
    27361 tatcagacaa gttcacagca aaaagaggcc actctaaaca ggtagcctct tcatttcttt
    27421 tttagtgttc ttttgttaaa atttcaaggg tttcgatgag gttttctgca ttaacttcaa
    27481 tgctgtcacc tgttgccttg attttaattt ccacgatacc ttcagcggct tttttaccaa
    27541 cagtgacacg aattggcaaa ccaatcaaat cgctatcaga gaatttcgaa ccgacgcgtt
    27601 cattacggtc atctgtcaag acatcatacc ctttagccat caagtcagct tctaacttcg
    27661 ccgtcaagtc ttgggccact tgatctttga cattaactgt aatcaaatgc acgtcaaatg
    27721 gggctaattc tttagggaag ttaatacccc aagcataacg gtaatcgcct tttggtgtct
    27781 tgttcacaaa gagacgggca tgctgttcaa tgacagcaga caaaatgcgg ctaaccccga
    27841 taccataaca acccatcaca attggaactg ttctgccatt ttcatcaaga attgttgctc
    27901 ccatgctgtc tgaataacga gtgcccaact tgaagatatg accgacttcg ataccacgcg
    27961 caaactggag aacaccatga ccatccggag acatttcccc ttctttgact tcacgaatat
    28021 ctacatattc agcctggaag tcacgtcctg gattaactcc tgtcatatgg aaaccatcct
    28081 tgttagctcc tgcaacggca ttggtaaggt tttgcacttt gcggtcagcc acaatgcgac
    28141 taccttgtgc caagttgaca ggcccaagtg agccaaaacc tgcaccaaag aaagcacggg
    28201 cttcttcttc actagctggc tctaaaaaat cagcagctag atagtttttt aatttaacgg
    28261 tattaatatg gtcatttcca actagcaaag caacaacagg ttcattatct gccacaaaaa
    28321 gcaaggtttt gatggtttgt gtttcatcta ctgaaagaaa agcagccact tcatcaatcg
    28381 ttttgcaatg tggtgtctca acttctgcca aggcatcttc agcagctact tttgaggacg
    28441 gtttgtattc gttagttgcc atctcaaggt tggcagcgta gcttgattct gttgaataag
    28501 caatagtatc ttcacctgaa atcatccaag cagccaattc tgctttaatc tcttctagaa
    28561 cctcttctgg aatatctgcg aggcttggga tagatttgtc caagaccacc caacggtcaa
    28621 ggtctgtacg ttctggtgta atagccatga attcttgaga atccttacca cccatagcac
    28681 caccatctcc aataatccct ttgaagtcta gacctgctct ggtaaaaata gcttcataag
    28741 cttgacgata gtcttcataa gtcacatcca agtcgtcgta atttggatgg aaactataac
    28801 cgtctttcat gatgaattca cgggtacgaa gcaagccatt acgcggacgt ttttcatcac
    28861 gatacttaga ctgaatttga taaaggttta agggcaattg cttgtaagat ttgaccgcat
    28921 cacgcaccaa agtcgtaaag gtttcttcgt gggtcggacc caagataaag tctgagttat
    28981 cacggttttt aagcttatag aggtcctctc cataggtctc ataacggcct gattcacgcc
    29041 agagatcagc tgtcaaaaga gctggtgcca acatttcaac agcaccgatc ttttcaaact
    29101 cttcgcgcat gatggtcttg aatttctcaa tggtacgatt tgccagtggt aaataagcat
    29161 agataccagc agaaacttgg cgcacataac cggcacgcac cataagcgcg tggctgataa
    29221 cctgggcatc acttggcatt tcgcgcaagg ttgggataag cagtttactt tgtttcatag
    29281 attattccgt tttaatacat ccccttatcc tcaaaccctt ctggaaacat caagtaagag
    29341 tgaagcggga ttattcaata atttgaatgt gtattccttt cattttgagt aagacctcaa
    29401 ttcttgcaaa tcttagggtt gaggtctttt tcgatcttta acatgataag gtcagcttaa
    29461 gatgacctat cttgattaga aaaagacgcg catgatatca ttccatgtca cagcaatcat
    29521 caatacgacc atgatagcaa ccccagctag ggtgatatag gcctctgttt cttgcttgat
    29581 aggcttgcga cgaatggctt caatgatatt catcaagatt tttcccccat caagtgcagg
    29641 aatcggaatc aggttaaaga tccctaaatt gatcgaaagc attgccataa gagataagac
    29701 tgactctaag ccgttttgag cagcctgatt ggacatgtca tacatggcaa caggtccacc
    29761 taatttattg agactaaagc cagtgatcaa tcctttcaaa gcattcaaaa tagtaaacgc
    29821 cccactccaa gctaattcta gaccgcctaa gagcttatcc ttaaatcctg ttttcagact
    29881 cgccttaact cctatcgtgt atgtctttgc atgcttttgt ggtttcacag ccaccgtttt
    29941 taagcgctga tgtgacttgt aggtgacctt aatggtctgt gacgggccta gatcccgtgt
    30001 tgcaaggtct acagcctcag tgagatcatt ccagctagtc accttgtaac cattaattgc
    30061 gacaatttgg tcattatctc gaagaccagc cttagctgct gctccatttt cttgaacacg
    30121 gacatgattg ctactaaaat ctggcatccc accttgtaaa aagaccaaga ggataaaaat
    30181 cacaatccct aaaataaaat tattcatggg acctgcaaaa ttggtgatta aacgtccgcc
    30241 aatactagca ttttgatatt gaacatcaag cggagcaatt cttatctcag taccgtcttc
    30301 ttcaacaata gtagcatcgt gagcgacctt atatgtcttg gtttcttcta aaaccaagcc
    30361 agtaatactc agctgatctt ctaagtcata gcctgtaacg tgcattggga gactcgttgg
    30421 gtctaactta ctttgagaca agttgatgcg cttaacaaaa ccttgctcat taagggttaa
    30481 acttgctgga gtacctgttt tgatctcagt tttatcatca ccccaaccag ccattcgcac
    30541 ataaccgccc aagggtaaca tcctcaaggt ataaagagtt cctccttggt caacatgaga
    30601 aaaaatttta gggcccattc caatggcaaa ttctcttact agaatgcctg attttttagc
    30661 aaaatagaaa tgtccaaatt catggacaat cactaaaata ccaaaaataa taataaaggt
    30721 tattattcct aacatagatt tcctttcagt ctattgcttt tttgagtttt gtcgcgttgt
    30781 tgcgactcca aacattacct cttaagatta aaataaacca aagagatgca tgatgggaaa
    30841 aacaaaaatc atggaatcaa agcggtctaa aataccacca tgtcccggga taagcttacc
    30901 tgaatctttg acaccaaagt gacgtttgag agcactttca accaaatcac caaattgggc
    30961 aaaaatggaa aaaagagcga ccaaaaccaa catggtcaaa aagtgatgtg gcgcataaac
    31021 agacctatca atcaccataa agataaaaga cacaaggact gcacaagcga tccctcctaa
    31081 actaccttca atggttttgt ttggagaaac tgtaggcaat agtttgcgtc tgccaaactg
    31141 acgcccaatc aggtatgctc caatatcagt ggcccaaacg ataaataagg ccaaaaagac
    31201 cttgtcaatt cctgacaggc gagcattgat caaatgttga aaaccaatcc caacataaaa
    31261 actagttgca atcggaaagg ccgcatcatc aaatgaataa gctctgctat ttaaaacagt
    31321 ccctgccaaa atgaaaaaaa ccattaagct gtaaaaagca acattcgcat caattggtaa
    31381 aaaagtgagg taatggtcca tcggaactgc caatacaaag gcggctaaca tggcaaaaac
    31441 accttcaaaa gaaaagactt ctaatctttt cattttcagt aattctgata ccccaatcat
    31501 ggccaaaacg cctacaaata attggaatgg taagtttcct attatgagaa aaggtaggaa
    31561 aatagctact gctactcccc cccaaacaac acgttctttc ataactatct ccttttagac
    31621 cttgccaaaa cgacgttggc ggtggttata atccgcaatg gcctttagta gctctgcctt
    31681 tttaaaatca ggccacaaga ctggtgtgaa ataaaattca ctgtaagctg attgccaagg
    31741 caagaaattg ctcaaacgca gctcaccact ggtgcgaata atcaaatcgg ggtctcggta
    31801 gagatatggc agatggtctg tcatcaagta attagcaatc aaatcctccg taatatctcc
    31861 tggatttaat ttggcatcta agacatcttg agcaataaag cgaacagcac tggtaatctc
    31921 agcacgtcct ccataattga gagcaaaatt caaaattaaa cccgtattac gttttgtttt
    31981 gtcgatggct gcatttagcg ctgccaaggt atcttcaggt aaacgactag tctctccaat
    32041 catttgaatc tttacattgt tctcatgaag cacaggcaca tatttgtcaa agaaggttac
    32101 tggtaaattc atgataaaag acacctcatc ttggggtctg gaccagtttt ctgtcgaaaa
    32161 ggcatagact gtcagaactt taacccccaa ctcagatgca gtaatcgtta cttcttgtaa
    32221 agcatccatc ccagctttat gcccaaacac tctaggtttt agtctttttt tggcccaacg
    32281 tccattacca tccatgataa ttccaatatg ctttgggata ctccccaaaa ctttttttgt
    32341 tgatttcgct tttaatccaa acatgttttt tccttattga taagcatact tatctcatat
    32401 tttatcatat ttcacgcctt ttggcttgtt ttttatcaat tagatcttat cttcacaaaa
    32461 tgttcaccta tcctctgata gatgtgtcag cttttcatga acctgttagc atcagaataa
    32521 ctgtttcagt ccagggatca aaacaaaaaa gtttggcata tttcatccaa actttccccg
    32581 ccttaatggc tttcaatggc actgtcagtg tcagtgctat ctactgtctc aacagcaggc
    32641 tcattaacaa cactggtttc ttctgtttca accagtgtcg tttctgtggt agcttttgtt
    32701 acaatacgct taatagctga tagctcaaat gtcaaaaaga cgccatccac atctaacaca
    32761 atctttttag ctgttgtatc gacttcgtca acaatcgcaa acatgccacc aatcgttacg
    32821 acttcgtctc ctttttcaat agcgtttaac tgattttggc gttcttgcgc ttgttttttt
    32881 tgttgacgtt gcataaacca aatcaatcca agcatcacta caaacattaa aattgttgga
    32941 aatcccataa tgtctccttt ttattctata aaagtcatgt cttactatat caaaaatcaa
    33001 gcggtatagc aagactagac gttacctgat ttcttcttta aacgagacgc taagcgcagt
    33061 gctttactca cgagtcaaaa aagctaagat gtcatctggt gtcaaacttg aatcacatac
    33121 agccctttgg tgctgatcgt aactaaccag caaagccgga actgtcacta attggtagtt
    33181 ctcacgaaag gcagcaagct cagcagcatc agcagcgttt tcgctatcca caaaatagac
    33241 gtctttttga ttatctgttg ccacttgtgc caacttagga gcaaagcggc gacaataagg
    33301 acagctcgaa cgtcctaaaa agacaatcat atctttgcca ctagcaatag ctgatgtgac
    33361 ttctgccaca ctcgacggta taaaattcgc aacgatctct tcaaatgtca tggatgtctc
    33421 cttctctttt ggtctcatga tacactaaag tagcaatttt ctcaatcaca aggtcttttc
    33481 acagctcaga gctttcatta ccaaaagatg gggttattta gcttttctca ttgatccagt
    33541 cttaccaaat aaacaataga gagaaccaag gggctctctc cattatgttt gcttatcagt
    33601 aaggtctctc aattcagagg attagttgtt ttctttgcgt tttgtaacgg ctaggacacc
    33661 agctgttgtc atcactgcta ctgctgctgc tgtaaagaat gggttggctt gctcaccagt
    33721 tgctggtaga cgtctgtggt tgttggctac aggtgtctta gccatattgc cattgcggcg
    33781 tcctggtgtt tggttagcct ctttgccagc aggtttttct ggggctggag ttacctcttt
    33841 gctcttttct ggagcttttt cacctggctt acctgcttca ccttgtgggc ctgctgggcc
    33901 ttgctcacct ggtttacctg cttcaccttg tgggcctgct ggaccttgct cacctggttt
    33961 gcctgcttca ccttgtgggc ctgctggacc ttgtgcgcca gtttcacctt tttcaccttg
    34021 tgggcctgct gggccttgct cacctggttt gcctgcttca ccttgtgcgc cagttgctcc
    34081 ggtttcgcct ttttcaccgc gctcaccttt ttcacccttt tcgcctggag ctccatcttt
    34141 accagcttca ccttgtgggc cttgtgcgcc agttgctccg gtttcgcctt tttcaccgcg
    34201 ctcacccttg tcacctttag gacctgctgg gccttgctca ccgcgttcac ctggtgctcc
    34261 ttgaaggcca tctttaccgt cttcaccttt aggaccttga aggccagttt cgccacgttc
    34321 tcctcttgga ccctgatcac cggtttcacc tttgtccccc ttaggtcctg gcttcccttc
    34381 tggtcccata tctcccttgt caccttggaa ggtgccattt tgtatacttt tagttacctt
    34441 ttctttccaa gtatcatctc tttttttcca ttcttctaaa tacgactgta ttttagttaa
    34501 ataatcttca acctgaagct gcccgttagg caatctacct tccctagaat tattaacttt
    34561 gggaacatac tccccagatg acttatccag ctccttttga agatcttcac ctacatatcg
    34621 catgctttca gcatcagcgc tgacgttcgc tacccccccg aaggtcgcca aaacagccgc
    34681 tgcagtggtt aggccatagc gatacacaaa tttattaata tttttttgtt tcataaagga
    34741 agctctc
//
LOCUS       DAUNLR010000016        32541 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUNLR010000016 DAUNLR010000000
VERSION     DAUNLR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32541
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.016"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            5..78
                     /locus_tag="VLL59_000757"
     tRNA            5..78
                     /locus_tag="VLL59_000757"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            158..231
                     /locus_tag="VLL59_000758"
     tRNA            158..231
                     /locus_tag="VLL59_000758"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:192..194,aa:Arg,seq:acg)
     gene            227..808
                     /locus_tag="VLL59_000759"
     CDS             227..808
                     /locus_tag="VLL59_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HER6508898.1"
                     /translation="MHNEKSNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYL
                     KDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQER
                     MQFQALIRGERFKGRRALLRKISPYFKEFAQQL"
     gene            993..1742
                     /gene="truA"
                     /locus_tag="VLL59_000760"
     CDS             993..1742
                     /gene="truA"
                     /locus_tag="VLL59_000760"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HER6508899.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            1732..2496
                     /locus_tag="VLL59_000761"
     CDS             1732..2496
                     /locus_tag="VLL59_000761"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HER6508900.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            2486..2956
                     /locus_tag="VLL59_000762"
     CDS             2486..2956
                     /locus_tag="VLL59_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HER6508901.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            2970..3530
                     /locus_tag="VLL59_000763"
     CDS             2970..3530
                     /locus_tag="VLL59_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HER6508902.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQFMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(3595..4440)
                     /locus_tag="VLL59_000764"
     CDS             complement(3595..4440)
                     /locus_tag="VLL59_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HER6508903.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            4761..6044
                     /locus_tag="VLL59_000765"
     CDS             4761..6044
                     /locus_tag="VLL59_000765"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HER6508904.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EEAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            6256..6831
                     /locus_tag="VLL59_000766"
     CDS             6256..6831
                     /locus_tag="VLL59_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HER6508905.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            7088..8692
                     /locus_tag="VLL59_000767"
     CDS             7088..8692
                     /locus_tag="VLL59_000767"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HER6508906.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            8860..9786
                     /locus_tag="VLL59_000768"
     CDS             8860..9786
                     /locus_tag="VLL59_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HER6508907.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQAGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLVKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPILFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            9840..9925
                     /locus_tag="VLL59_000769"
     tRNA            9840..9925
                     /locus_tag="VLL59_000769"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9874..9876,aa:Leu,seq:aag)
     gene            10133..11014
                     /locus_tag="VLL59_000770"
     CDS             10133..11014
                     /locus_tag="VLL59_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HER6508908.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            11396..11584
                     /locus_tag="VLL59_000771"
     CDS             11396..11584
                     /locus_tag="VLL59_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HER6508909.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            11736..12101
                     /locus_tag="VLL59_000772"
     CDS             11736..12101
                     /locus_tag="VLL59_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HER6508910.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            12101..13765
                     /locus_tag="VLL59_000773"
     CDS             12101..13765
                     /locus_tag="VLL59_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HER6508911.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            14002..14892
                     /locus_tag="VLL59_000774"
     CDS             14002..14892
                     /locus_tag="VLL59_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HER6508912.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGKYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            15122..15976
                     /locus_tag="VLL59_000775"
     CDS             15122..15976
                     /locus_tag="VLL59_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HER6508913.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            16169..17365
                     /locus_tag="VLL59_000776"
     CDS             16169..17365
                     /locus_tag="VLL59_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HER6508914.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGAKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            17628..18179
                     /locus_tag="VLL59_000777"
     CDS             17628..18179
                     /locus_tag="VLL59_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HER6508915.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            18246..18617
                     /locus_tag="VLL59_000778"
     CDS             18246..18617
                     /locus_tag="VLL59_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HER6508916.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            18655..20001
                     /gene="glnA"
                     /locus_tag="VLL59_000779"
     CDS             18655..20001
                     /gene="glnA"
                     /locus_tag="VLL59_000779"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HER6508917.1"
                     /translation="MAITVADIRHEVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPIEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFISQWEIDHYIHNY"
     gene            complement(20229..21911)
                     /locus_tag="VLL59_000780"
     CDS             complement(20229..21911)
                     /locus_tag="VLL59_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HER6508918.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGAHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(21913..22143)
                     /locus_tag="VLL59_000781"
     CDS             complement(21913..22143)
                     /locus_tag="VLL59_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HER6508919.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            22428..23126
                     /gene="tsaB"
                     /locus_tag="VLL59_000782"
     CDS             22428..23126
                     /gene="tsaB"
                     /locus_tag="VLL59_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HER6508920.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHASLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            23098..23553
                     /gene="rimI"
                     /locus_tag="VLL59_000783"
     CDS             23098..23553
                     /gene="rimI"
                     /locus_tag="VLL59_000783"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HER6508921.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLVSQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            23543..24571
                     /gene="tsaD"
                     /locus_tag="VLL59_000784"
     CDS             23543..24571
                     /gene="tsaD"
                     /locus_tag="VLL59_000784"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HER6508922.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(24742..25011)
                     /gene="rpsN"
                     /locus_tag="VLL59_000785"
     CDS             complement(24742..25011)
                     /gene="rpsN"
                     /locus_tag="VLL59_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HER6508923.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(25247..25990)
                     /locus_tag="VLL59_000786"
     CDS             complement(25247..25990)
                     /locus_tag="VLL59_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6508924.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSC"
     gene            26230..27009
                     /gene="udp"
                     /locus_tag="VLL59_000787"
     CDS             26230..27009
                     /gene="udp"
                     /locus_tag="VLL59_000787"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HER6508925.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            27030..28232
                     /locus_tag="VLL59_000788"
     CDS             27030..28232
                     /locus_tag="VLL59_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HER6508926.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKGVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDYKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            28262..28933
                     /gene="deoC"
                     /locus_tag="VLL59_000789"
     CDS             28262..28933
                     /gene="deoC"
                     /locus_tag="VLL59_000789"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HER6508927.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(29028..30197)
                     /locus_tag="VLL59_000790"
     CDS             complement(29028..30197)
                     /locus_tag="VLL59_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HER6508928.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSADQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            30865..>32541
                     /locus_tag="VLL59_000791"
     CDS             30865..>32541
                     /locus_tag="VLL59_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6508929.1"
                     /translation="MKLKLSVIGLFFCLIAAIGVISISDTQKPVPLPIDGAFSIQGKS
                     SLSSDEVYKKISNLSKTKNVNIYKPIVRNSGQLTYINFKNTNYEQLKPAPITGMYYTL
                     GKIDSSSLKVLTASGLKLIYAAYPWYIGGILQFDGTLRLLLMLSIYLTLLVVLFVVRT
                     RQIKEGVIRHSLGLPIYNLRRDYVISFTFELVMAGLLMIAYSYFWGSGLFTYSSKLFF
                     SLILTNLIIFQIVDIITFILFWLTIRVEKPIEIIKNKAKNSFLFIVWLVIISIIIIVS
                     GIFLQETKASQSRINRQISQLSPWNKVRNWKRLELLGIENGSINNGEINEPESQYIQI
                     ATALKKLDFIYIKPSSVYIPDYMKNTNFAEDFFKKLNNDGITDPEVNKEMIYINKSGA
                     NIQNKVNGTDYQLLDNKVATIYIPDKFKEKKKSIENTVVAEQFTGTKYTKENLAVQII
                     PNEKKIFYFNENGNEHDENKEASPMANVTDSKGNIVVVLDTDKMVASKDFSLASNIVN
                     SSLFSPEAIKKINDLSLHLNFSINPVDVYQLVKLNIQSLKHQIFLSKVLQK"
BASE COUNT        10431 a         5256 c         6815 g        10039 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gagagaggta gggagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggtaagatag aggcaagata tgcgttggca cccttagctc aactggatag
      181 agtacctgac tacgaatcag gcggttagag gttcgactcc tctagggtgc ataatgaaaa
      241 aagcaacagg acattagtgt cctgttgttt ttttgtggtt ctctttatac tagggatagt
      301 taaaaagaaa aggagactca aaatgtcgat agagacaaga gcagcgtttg aaaaagttaa
      361 gcccattatt ttgaaattaa agcgacacta ttatattcaa ttgtgggata gagatgactg
      421 gttacaagaa ggacatatta tcttattaca gttactagaa aggtacccag agttaattga
      481 ggaagaagag cgtttatatc gctattttaa aacaaaattt tcatcttatt tgaaagattt
      541 attacgccgt caagaaagtc aaaagcgtca gttccataag ttagcatatg aagagatagg
      601 ggaggttgca catgccattc catcgagagg gttatggcta gacgactatg tggcttatca
      661 agaggtaata gctagcttag agaaccaatt aaattcgcaa gagcgtatgc agtttcaagc
      721 acttatcagg ggcgaacgtt tcaagggaag acgtgctcta cttaggaaga tcagtcccta
      781 ttttaaagaa tttgcacagc agttgtaagc aagacctata aggaattggg ggtaaatcta
      841 tgaaaaaagg agagagtttg gaggaaatag ctttcttata gcttttaaat cgctagtggc
      901 ttagagtaag cttcaatacg tctttcattt gtttgggtac agtttgatta aaaatagttt
      961 ctcttacgtt taagaaatgt taaaatagta acatggtaag atacaaagca acgatttcct
     1021 atgatgggac tcttttttcg ggttttcaaa gacaaagaca tttacgtacg gttcaagaag
     1081 agattgaaaa aacactctat aaattaaata acggtacaaa aattataatt catggtgcag
     1141 gacgtacgga tgcaggagta catgcttatg gacaggtgat ccattttgat ttgcctcaag
     1201 aacaagaagt tgaaaaatta cgatttgctc ttgatacaca gactcctgaa gatattgatg
     1261 ttgttaatat agaaaaagtg gctgatgatt ttcattgtcg ttatcagaag catttaaaaa
     1321 cttatgaatt tttagttgat aatggtcgac ctaaaaatcc gatgatgcga cactatacca
     1381 ctcattaccc ttatactctt aatattaaac ttatgcaaga agctattaac ggtctggtag
     1441 gtacacacga ttttactggt tttacagcag caggaacttc ggtacaaaat aaggtgcgaa
     1501 cgattaccaa agcaacggta tctcgggatg aaaaaactga ttttttggtg tttacttttt
     1561 caggaaatgg ttttctctat aagcaggtga ggaatatggt gggaactttg ctgaaaattg
     1621 gtaatggtca aatgccagtt gaacaagtta aagtgatttt gagctccaaa aatcgtcagc
     1681 tagctggacc aacgatatct ggaaatgggc tttacttgaa ggagatttgt tatgaaaact
     1741 gattatatcg tgactatatc tgggaacgat attttaagtg gaggtggtct ctatgctgat
     1801 ttagcgactt acataaggta tgacctacag gcctttgtag cggtaacttg tttaactact
     1861 agatctgaag agggctttag tctatttccg gtagctaaag aaattttccg tgatcagttg
     1921 aatagcttta cgaacgctcc aatttctgct attaaaattg gtttgttacc taatgcggaa
     1981 atgtgtgaaa tagttttgga ttttataaag gggcatctgg gaatcccagt ggttttagat
     2041 cctgttctag catgtaaaga aatagatgat gttaaaatag ttcctctaag acaggagatt
     2101 ttacaattat tgccttatgt aactgttgtt actccaaatt tggtagaggc tcagctatta
     2161 tctcaaaaag agattgtttc tttaaaagat atgcaagaag ctgctaaata tttttatcaa
     2221 cttggggcaa aacaggtggt tatcaagggt ggtaatcgat ttagtcagaa aaaggctatt
     2281 gatctttttt atgacggtaa agagattgtt accttggaat gtcctgtact tgagaaaaat
     2341 aatattggcg caggctgtac ttttgcatct agtatcgcta gtcagttagt aaagaaaaaa
     2401 acgccactag aagctgtgaa aaactcaaaa gagttagtct accaagctat tttacaatct
     2461 gatagatacg gagtaaaaca aagttatgca aaatagtaag atacgacaaa tgagtttaac
     2521 agggatattg acagcattgg ttgttgtttt aggaagattt gtcatgctac ctactccaac
     2581 aggtttttta acgctgttgg atgcaggaat ttatgctgtc agcttttcct ttggatcagc
     2641 tcaaggagct attgtgggag ggttatcagg ttttttaatc gatttagtgg caggataccc
     2701 tcagtggatg tttcatagtt tgattgctca cagtgtccaa gggtattttg cgggatggag
     2761 agggcgcaag cgttggcttg gtgttgtgat aggttctttt atcatgattt tttggtactt
     2821 tttaggctct cttatgcttg gttatggcct ttcgggatct ttagccggta tttggggaaa
     2881 cgtcatgcaa aatacattag ggctttttgt tggttttatt atctttaagg ccatattaag
     2941 gcaaaaaaag agataaggag agtgagaagt tgttgaataa tttagagaaa caaacaaggg
     3001 aaatcgtcat tgatgttgta gaacgctctg ctattcaacc aggtaatctt tttgttctag
     3061 gtctttcatc tagcgaaatt ttgggtagta gaattggaaa acaatctagt ctagaagtag
     3121 gtcaaatagt tgttgaagtt gtgttagatg aattaaataa gcgtggtgtt catttggctg
     3181 tacaaggttg tgaacacgtc aatcgtgcct tggtagtaga gaggcatgtg gcagaatcta
     3241 agcagttaga gattgtcaat gtggttccga atcttcatgc tggtggcagt gctcagatgg
     3301 ctgcttttca atttatgtca gaccctgtcg aagtagaaga agttattgca cacgctggac
     3361 ttgatatagg tgatactgct ataggaatgc atattaagcg tgttcagatc cctctgattc
     3421 cttgtcaacg agagctagga ggtgctcatg tgacagcttt ggctagtcga ccaaaattaa
     3481 ttggtggagc tagggctgat tacaatatgg atattatccg taaatcctaa accctttttt
     3541 ctggaataaa acaattggtg ttttttctag aaaaaaggat tttttaagat tatattaaga
     3601 ttttgaggtg atagaatagc tgattgcagt cggtaattga atgccttctt tgagtaaagc
     3661 ttcttgataa agtctataaa aagtatggta aatcttaaat tgttctccat tttctgtgaa
     3721 aatagcaatt ctaaaagtga actgtccatt agagttattt tgaggcccta aaatatttgg
     3781 tttgccaacg atttgaggat ggtttggcaa ttccttttga ttcacttcat caatgattcg
     3841 agtgacttgg ctcaaattaa cagtggaata aagaggaatt tcaattaagg cacgcatatt
     3901 accacgagat ttgttgctga caacggtgat gctacggttt gggatgaaat gtagtgttcc
     3961 atcgaatcca cgaatttgag tagttctaat tccaacacca aagacactgc cttctatgtc
     4021 agagatagta acgttatctc ctacttcaaa ttgattctca aataagataa aaaagccatt
     4081 gacaacgtca gataaaaatc cctgtgcacc taacccgatt gctactccag caattccagc
     4141 tcctgctaga agactagaga caggtatgcc aaataagcta agtatccaat aaatgagaag
     4201 aaaatacaat aagtaattta aaatattgtg agtgagctta gagagtgttt ttttgcgagc
     4261 ttcactttgt cttgaataag caaacgattt gttaatggtt ttttcaaaaa gatagttagt
     4321 aacacgtttt aaaatagcaa aaaagagtaa tagaataatg agagacacta gctttttaaa
     4381 aatcgttaag ccaatatttt cgatatgaga ctgctctagg taatgtaata taaatgtcat
     4441 gagaaatcct ttctttgata gtttatcaaa aaaaaaccaa tcttgaaaag agataaatta
     4501 atattttaac caaagttatg ataattgttt tatcataaag aatgccatag tcatccgttg
     4561 tgataatgct tgaaaatagt cagttagtaa gcgaaaaagt ctaacattaa cctttataaa
     4621 ttgaaaataa ctgttagtag actaatgaca ggtagatact cttaatagcg cgtttgattt
     4681 cacgcataaa aagctttaaa aacgctttaa attatgataa aatgaactgt atcgaaatta
     4741 ttttaaggag aaatgactta atgtctacat catttgaaaa caaagctaca aatcgtggcg
     4801 tgattacatt tacaattagt caagataaaa taaaaccagc tcttgataaa gcttttaata
     4861 aaatcaaaaa agacttaaat gcaccaggtt tccgtaaagg acacatgcct cgtccagtct
     4921 tcaaccaaaa atttggtgaa gaagttcttt atgaagatgc tttgaatatt gtattgccag
     4981 aagcttatga agcagctgtg acggaacttg gtcttgatgt ggttgcacaa ccaaaaatcg
     5041 atgttgtgtc aatggaaaaa gggaaagagt ggacactttc tgctgaagtt gtgacaaaac
     5101 ctgaagtgaa acttggtgat tacaaaaacc ttgttgtaga agttgatgct tcaaaagaag
     5161 tttcagatga agacgtggat gctaaaattg agcgcgaacg tcaaaacctt gcggaactca
     5221 ttattaaaga cggtgaagca gctcaaggtg acactgttgt gattgacttt gttggttcag
     5281 ttgatggtgt tgagtttgat ggcggtaaag gagataactt ctctcttgaa cttggttcag
     5341 gacaatttat cccaggtttt gaagatcaac tagttggtgc taaagctggc gatgaagtag
     5401 aagttaatgt cacattccca gaatcttacc aagcagaaga tcttgcaggt aaagccgcta
     5461 aatttatgac aactattcac gaagtcaaaa caaaagaagt accagagctt gatgatgagc
     5521 ttgcaaaaga tattgatgaa gatgttgaca cacttgaaga cttaaaagta aaatatcgta
     5581 aagaacttga agaagctcaa gaaactgctt atgatgatgc tgttgaagga gctgcgattg
     5641 aattagcagt tgcaaatgct gaaattgttg atttacccga agaaatgatt catgaagaag
     5701 tcaaccgttc agtgaatgaa tttatgggca acatgcaacg tcaaggaatc tcacctgaaa
     5761 tgtacttcca attgactggt acaactcaag aagatttaca taaccaatat tcagctgaag
     5821 ctgacaaacg tgttaaaaca aaccttgtta ttgaagcaat tgctaaagca gaaggttttg
     5881 aagcaacaga tagtgaaatt gaacaagaaa ttaatgacct tgcaacagaa tataacatgc
     5941 cagctgacca agttcgttct cttctttcag cagatatgtt gaaacatgat attgcaatga
     6001 aaaaagcagt tgaagtgatt acaagcacag caagcgttaa gtaatcttat taaggaacaa
     6061 aacgtacaag ccggattaga acgtctttct agtctggttt ttctttttct aaagataagg
     6121 aattagttaa acgttatttt aatgaattag ctttaaagat ttgtcaagaa gaagtgatat
     6181 gagttgataa aagttttgac gaattacttt ttttagcgta aaatggtaga gaatgataaa
     6241 ataaggagaa ctgccttgaa attagacgta tttgcaggac aagaaaaaag cgagctttcc
     6301 atgattgaag tggcgcgtgc cattttggaa gaacgcggtc gcgacaatga gatgtacttt
     6361 agcgatttag tcaatgagat tcaaaattac ttaggaaaat ctgatgcagg tattcgtcat
     6421 gcattaccat ttttctatac tgacttaaat acggatggct catttattcc tctaggtgaa
     6481 aacaaatggg gacttcgttc gtggtatgct atcgatgaaa ttgatgaaga aattattact
     6541 ctagaagaag atgaagatgg cgcacaaaaa cgtaagaaaa aacgcgttaa tgctttcatg
     6601 gatggagatg aagacgctat tgattataga gatgatgatc cagaagatga agatttcaca
     6661 gaagaatcag ctgaggttga atatgatgaa gaagatccag atgatgaaaa atcagaagtg
     6721 gagtcatatg attcagaatt gaatgaaatt atccctgaag atgattttga agaagttgat
     6781 atcaatgaag aagacgaaga agatgaagaa gatgaagaac cagttctcta atgtctttag
     6841 ttcagaaata aaaatgtaat tatcatttga caaattgtct attatagttt atattattat
     6901 tcgggcacct ctttatgagg tcaggcaaaa gctctctagt taataggggg ctatttttgt
     6961 tttctagaat aatgccagtt tgcctctata tttagaaaac taaggtgata cctaaccaat
     7021 gtggaaccaa ctaataggga attaacaaga aagcaatgct tttattcagc ttatataaag
     7081 gagtactatg acgaaataca tttttgtaac tggtggtgtt gtatcatcaa ttggcaaagg
     7141 aattgttgcg gcaagtcttg gccgattgtt aaaaaatcgt ggacttaagg tgacgattca
     7201 aaaatttgat ccttatatta atattgatcc agggacgatg agcccctatc agcatggaga
     7261 agtatatgtg acagatgacg gtgctgaaac cgacttggat ttgggtcact atgaacgttt
     7321 tattgatatc aatcttaata aatattccaa tgttacaaca ggtaaaattt atagtgaagt
     7381 ccttcgtaaa gaacgtaaag gtgagtacct tggagcgact gttcaggtga ttcctcatat
     7441 cacagatgcc cttaaggaaa aaatcaaacg cgcagcttca acaacggact ctgatgtaat
     7501 tattactgag gtcgggggga ctgttggcga tattgaaagt ttaccgttct tagaagctct
     7561 tcgtcagatg aaagctgatg ttggttctga aaatgtgatg tatattcaca ccaccttgtt
     7621 gccatattta aaggcagcgg gtgaaatgaa aactaagcca acgcaacatt ccgttaaaga
     7681 attgcgtggt ttagggattc aaccgaatat gttggttatt cgtacggaag agccagttga
     7741 gcaggggatt aaaaataaat tggctcagtt ctgtgatgtg aattcagaag ctgttatcga
     7801 gtcacgtgat gtagaacact tgtatcaaat tccattgaac ttgcaagctc aatcaatgga
     7861 tcagattgtt tgtgatcatt tgaaattgaa tgcgccacaa gctgatatga ccgagtggtc
     7921 agctatggtt gacaaggtga tgaatttaag aaaaacaaca aaaattgcct tggttggtaa
     7981 atatgtggaa ttgccagatg cctacttatc tgttgtggaa gccttgaaac attctggtta
     8041 tgccaatgat accgcaattg acctaaaatg ggtcaatgct aacgatgtga cggtggataa
     8101 tgcagctgac ttgttgggag atgcggatgg gattattgta ccaggtggtt ttggtcaacg
     8161 tggtacagaa ggcaagatcc aagcgattcg ctatgcccgc gaaaatgatg tgccaatgct
     8221 tggtatctgt cttggcatgc agttgacctg tgttgaattt gcccgccatg tcctcaatat
     8281 ggaaggtgca aactcttttg aattagagcc aagtactaaa taccccatca ttgatatcat
     8341 gcgtgatcaa attgatattg aagatatggg aggtacgctt cgtctgggat tgtacccatg
     8401 taaattgaaa ccaggttcaa aagcagcaat ggcatacaat aatcaagagg tggtgcaacg
     8461 tcgtcatcgt caccgttatg agttcaacaa caaattccgt ccagaatttg aagcagctgg
     8521 ttttgttttc tcaggagtat cacctgacaa ccgcttagtt gaaattgtag aattgaaaga
     8581 gaaaaaattc tttgtagcag ctcaatacca cccagaattg caaagccgtc caaatcgtcc
     8641 tgaggagcta tacaccgctt ttgttacagc tgctattaaa aatagcaatt agtggtttta
     8701 agggtaagtt tgtggcattc tacttggctg gcagatactg ataaagatta ctagctatta
     8761 gagggatctt ttctataaaa atagcattag aaaaagaaaa acgtgatatt tttaggttag
     8821 cactttcttt ttcagtcatt tttttgtaaa atacttggta tgaaaactat tcgaatagca
     8881 aagtatttag gaattctatt ccttttgata actcttatta gcgtaggtgc tagtttttat
     8941 ttctttcatg ttgcacaaat aagagaagag aaatcgttta ttaataataa gaaacggagt
     9001 acaaataatc cattataccc agctgaacag tcttttgacg ctttacctta cgaaaaacgt
     9061 caactaacaa atcgtgggtt aaaacaagcg gggtggtact taccagctgc tcaaaaaaca
     9121 aaaaagacag ctattgttgt tcatggtttt acgaatgaca aagaagatat gaagccatat
     9181 gccatgcttt ttcatgattt gggctataat gtcttaatgc cagacaatga ggcccatggg
     9241 gaaagtgaag ggaacttgat tggttatggc tggaatgacc gccttaatgt catggcttgg
     9301 acagaccaac tggttaagga aaaccctgaa agccaaatca cactctttgg cttatctatg
     9361 ggtgctgcaa cagtaatgat ggcaagtggt gagcgattgc ctgcgcaagt cacctccctc
     9421 atcgaagatt gcggttatac cagtgtttgg gacgaattga agtttcaggc caaggctatg
     9481 tacaacttgc ctgcctttcc tttactctat gaagtctctg ccttatctaa gattcgagca
     9541 ggttttagtt acggagaagc gagctcagtg aaacagctgg ctaaaaataa acgtccaatt
     9601 ttatttatcc acggtgataa ggatgatttt gttcctacaa aaatggttta tgacaattat
     9661 aaggccacga aaggtcctaa ggaaatcttg attgttaaag gggcaaaaca cgccaaatcc
     9721 tttgaaacaa acccagaaca ataccagaaa aaaattgccg cttttttgaa aaaagttgag
     9781 aaataagtat tgacagttaa actcacagtt gctataataa tttatgttac tgatgagtag
     9841 cggggatggc ggaattggca gacgcgcagg actaaggatc ctgtgaccgc tttaggtcgt
     9901 gtgggttcaa gtcccactct ccgcataatg taagaggtga atcattgatt cgtctctttt
     9961 tgtttggtta aatgaaggat aagaaggcat agatttaccg gagaaaactt ttgataatct
    10021 gcttttggaa aacgctttaa gcttgtgaaa gactagaaat ttatggaaaa ttgtgctaga
    10081 atgaacaatg taaacgggga gttatcccga aaaataagag gaggccttac aaatggcaat
    10141 cgtttcagca gaaaaatttg tccaagcagc tcgtgaaaac ggatatgctg ttggtggatt
    10201 taacacaaac aacttagagt ggactcaagc aatcttgcgt gcagcagaag ctaaacaagc
    10261 tccagttctt atccaaacat caatgggtgc agcaaaatac atgggtggtt ataaagtatg
    10321 tcaatctctt attactaacc ttgttgagtc aatgggtatc actgttcctg ttgctatcca
    10381 ccttgatcat ggtcactacg aagatgctct tgagtgtatc gaagtaggtt acacttcaat
    10441 catgtttgac ggttcacacc ttccagttga agaaaacctt gctaaaactg cagaagttgt
    10501 taaaattgca catgctaaag gcgtttcagt tgaagctgaa gttggtacaa tcggtggtga
    10561 agaagacggt atcatcggta aaggtgagct cgctccaatc gaagatgcta aagcaatggt
    10621 tgaaactgga attgacttct tggcagctgg tatcggtaac atccacggtc catacccaga
    10681 aaactgggaa ggtcttgctc ttgaccactt agaaaaatta acagcagctg taccaggttt
    10741 cccaatcgta ttgcacggtg gttctggtat tcctgacgat caaatcaaag aagcaatccg
    10801 tcttggtgtt gctaaagtta acgttaacac cgaaagtcaa atcgctttct ctaacgcaac
    10861 tcgtgaattt gctcgtaact acgaagctaa cgaagcagaa tatgatggta aaaaattatt
    10921 tgacccacgt aaattcttgg ctccaggtat gaaagctgtt caaggtgctg ttgaagaacg
    10981 tatcgatgtt ttcggatcag ctaacaaagc ataatttaga gtattaaata ccctaaagcc
    11041 ctcttgaggg cttttttaga tacaattgac atcttaaaat ggataccagt ttctgtgaaa
    11101 caatctttga ttgtgaacaa acaaagcata atttagagta ttaaaatctg gaccctgcta
    11161 tctatggtaa gtctttttgt tattgttaaa gaggttaagc ggaatgttaa tatgttttag
    11221 ctaaaaaatg tagtgaaaaa tgagtacgta gactattgta atagtaattc cgtaaaattg
    11281 ttgaaaaaga aaatgggaaa taccttgtca aattaagcac cctatgatag aatagatagg
    11341 tatgtggtgc tagcacatcc gtaaacatat tctacgtagg aggaaacaga tcaaaatggc
    11401 taaagtatgt tattttacag gacgtaaaac cgtttctgga aacaaccgtt cacacgcgat
    11461 gaaccaaaca aaacgtacag ttaaaccaaa ccttcaaaaa gttactatcc ttgttgatgg
    11521 taaacctaaa aaagtttggg cttctgctcg tgcgcttaaa tctggtaaag tagaacgcat
    11581 ctaatagaaa taagccttag ggcttttttt attagcttat ttctatccat aagctagtca
    11641 aggtaataaa cgctatcgtt aactattcta tctcttttac attacttcta aaatatgata
    11701 aaataggatg ataaaaactt tttgaggtag taactatgac tgtaaaaatt aatacaaaag
    11761 atggtctaat cgagctatcc gacgatgtga ttgcaactgt cgtgggagga tcagcaacgg
    11821 aaatttttgg tgttgttgga atggccagca aaagtgcaat aaaagacaat tttcaatcac
    11881 tacttcgcaa agaaaactac gctaagggtg ttgtagtaaa atcaacagat ctgggtattt
    11941 ctgttgatgt ctacactgtg atgagttatg gtgtgaaaat cagtgaagtc tctaaaaata
    12001 tccaagaacg cgtgaaattt aaccttgaaa gtcagcttgg tctcactgct gatatggtca
    12061 atgtttacgt gcaaaatatt aaggttgtag gagaaaatta gtgtcaaata ttacaacaag
    12121 cttattccaa gaaatggtcc aagcggcagc gactcgcctt ggcaaacaag cagaatatgt
    12181 taattcctta aatgtttttc ctgttccaga tggtgataca ggaacaaaca tgagcatgac
    12241 tatggacaat ggtgccaagg aagttgctga taaacctgcg tcaactgtgg gagaagttgg
    12301 acaaatgtta tcaaaaggtc ttttgatggg agcgcgtgga aattctggag ttattacttc
    12361 acaacttttt cgtggttttg gtcaaagcat taagggaaaa gatgagctga caggtaaaga
    12421 tttggcacaa gcctttcaag tgggtgtaga agttgcctac aaagcagtga tgaaacctgt
    12481 tgaaggaaca attttaactg tttctcgggg tgcagcgact gctgccttaa aaaaagcaga
    12541 ccttacagac gacgccgtgg aagtcatgca agctgcttta gatggtgcca aaggtgccct
    12601 tgctaagact cctgatttac ttcctgttct taaagaagtt ggtgtggttg attcaggcgg
    12661 tcaaggtctt gtctttatct atgaaggttt cctatctgct ttgaatggcg actatgtgac
    12721 ttcagcagac tttaaagcga ctcctgctaa catgtctgaa atgattaatg ctgagcatca
    12781 caaatccgtt gttggtcatg tggctactga agacattacc tacggttatt gtactgaaat
    12841 catggttgcc cttaaacaag gcccaaccta tgtgaaagaa ttcaactatg atgagtttca
    12901 aggctacctt agtggccttg gtgactcgct gttagtggtc aatgatgatg agattgttaa
    12961 agttcacgtc catactgaag accccggact tgtgatgcaa gaaggtctta aatatggttc
    13021 gctcatcaag attaaagtgg acaatatgcg taaccagcat gaagcacagg ttcaaaagac
    13081 tgatgtcgaa aaaaacaagg ctgaagtaaa agactttggc ttgattgcag tagtagctgg
    13141 agaaggttta tctgaaattt tcaaggcgca aggtgttgat tacgtgattt ctggtggtca
    13201 aaccatgaat ccatctacag aagatattgt taaagctatt gaagcagtta atgccaaaca
    13261 agtcattatc ttgccaaaca ataaaaatat ctttatggct gcccaatctg ctgcagaagt
    13321 ggtggatatt ccggctgctg ttgttgcaac acgtactgtt ccgcaaggat ttaccagctt
    13381 gttggccttt gatccttcaa aatctttaga ggacaatgta gcagatatgt caactagtct
    13441 ttctgacgtg gtcagtggaa gcgttacttt ggcagtccgt gacaccacca ttgatggttt
    13501 agaaatccat gaaaatgatt tcttgggaat ggttgatggt aaaatcatcg tttcaaaccc
    13561 agacatggaa gcaactctaa aagctgcctt tgaaaagatg attgacgaag atagcgagat
    13621 tgtgactatc tttgttggtg aagaaggtga ccaagactta gcagaagaac ttgctgggta
    13681 tttaggagag acttacgaag atgtggaagt tgagatccat caaggagatc agcctgttta
    13741 cccatatctc atgagtgtag aataatagaa tacaataaaa aaagaggagt taggcaaagg
    13801 tctgactctt tttgtctata ttgatgtcgt aatgagtggt tttagtgatg gtaaacccct
    13861 aaaaaatgag ggtaattcat cacaaagcta atggttacga tttaatttga caaaacctag
    13921 aaaaacatta taattgtatt ataacaataa gtcaagaact gaaaacgatt cagttctaag
    13981 acatgacaag gaggagattt tatgttagga ccatttatct ttattgcttt tggggttatt
    14041 gtaatcctag ctattgttgc cagtaccctt tatgttgttc gtcaacaatc tgttgccatc
    14101 gtggaacgtt ttggtaagta ccaaaaaaca gccactagtg gtattcatgt ccgccttccg
    14161 tttgggattg acaaaattgc tgcgcgtgtg cagctgcgtc ttttacagtc agaaatcatc
    14221 gttgaaacca aaaccaagga caatgtgttt gtaactttga atgttgccac tcagtatcgt
    14281 gttaacgaac aaaatgtaac agatgcttac tacaaattaa tgaaacctga atctcaaatc
    14341 aagtcttata ttgaagatgc cttgcggtca tccgtgccga agttgacctt agacgaattg
    14401 tttgagaaaa aagatgaaat tgccttggaa gtacaacatc aagtggcaga agaaatgtca
    14461 acctatggat atattattgt caaaaccttg attaccaagg tggagcctga tgctgaagtc
    14521 aaacagtcaa tgaatgaaat caatgcggct caacgcaaac gtgtagctgc tcaagagttg
    14581 gcaaacgcag ataaaattaa aattgtgaca gcagcagaag cagaggctga aaaagatcga
    14641 ttgcacgggg tagggattgc ccaacagcgt aaggccattg tggatggttt ggcggagtct
    14701 attcaagagc ttaaagaagc gaatatttcc ttaaacgaag aacaaatcat gtccattttg
    14761 ttgaccaacc aatacctgga taccctcaat acctttgcgg caaaaggaaa ccaaaccctt
    14821 tttctaccaa atacaccaag tggggtagag gatatccgta cacaagtttt atctgccctt
    14881 aaaacaaaat aacgtgtaaa agcttggcta aaaagttgct caatactgga tttagcagaa
    14941 ggctatcata ccttgtgaag tggcaaacga cgaaatgaat acattacttt tattggagaa
    15001 atgaaagtaa aaaaagcctt tttcatgatt aacaacatag tattgattaa atgttaagtt
    15061 gtattgactt ttaaattaaa taagtttaaa atcaatttaa taagcaaaaa ggagattttc
    15121 aatgaaatcc aaaaaagttg ttagtgttat atcacttacc ttatcccttt ttttggtgac
    15181 aggttgtgct aaagttgata acaacaaatc agttaatcgt aagcctgcta ctaaacaaac
    15241 ctataatagc tatagtgatg accaattaag atcgcgtgaa aataccatgt ctgttttatg
    15301 gtaccagcga gctgcggaaa ctcaagcgct ttatttacag gggtatcagt tagcaacgga
    15361 tcgcttaaaa gaacaactca ataaaccaac ggataaacct tattcaattg tattagatat
    15421 tgacgaaaca gttcttgata atagccctta tcaagctaaa aatgttttgg aaggaacagg
    15481 atttacacct gaaagctggg attattgggt acaaaagaaa gaagcaaaac cggttgctgg
    15541 tgctaaagac tttttgcaat ttgcagacca aaatggtgtt caaatttact acatttcaga
    15601 cagatcaact actcaagtag atgctacaat ggaaaatctc caaaaagaag gtattccagt
    15661 acaaggtcgt gatcatcttc tattcttaga aaaaggcgta aaatcaaagg agagtcgtcg
    15721 tcaaaaggtc aaagaaacaa ctaatgtaac gatgctattt ggtgataatc ttctagattt
    15781 tgctgatttt tcaaaaaaat ctcaagaaga cagaacagct ttattatcag atttgcaaga
    15841 agagtttgga agacgcttta tcattttccc taatcctatg tatggttcat gggaaggtgc
    15901 catttataaa ggtgaaaagc tggatgtgct taagcaacta gaggaacgcc gtaaaagttt
    15961 aaaaagcttt aaataaagta attgaaaaag aggtgcaaaa gaaaatgtaa cctcttttta
    16021 agtactatta ttttctgaaa atagggttaa tgactgaaaa aaatgttgat tttgtgaaat
    16081 gattatttta ttattttcat attttatctt tatgctagga attgtggtat aatggaggag
    16141 tataaaaaat attaaggagt ctattcacat ggctaaattg actgttaaag acgttgattt
    16201 gaaaggtaaa aaagtcctcg ttcgtgttga ctttaatgtg cctttgaaag acggcgttat
    16261 cactaacgac aaccgtatca ctgcggctct tccaacaatc aagtatatca tcgaacaagg
    16321 tggtcgtgct atcctcttct ctcaccttgg acgtgttaaa gaagaagctg acaaagaagg
    16381 aaaatcactt gcaccggtag ctgctgattt agctgctaaa cttggtcaag atgttgtatt
    16441 cccaggtgtt actcgtggtg caaaattaga agaagcaatc aatgctttgg aagatggaca
    16501 agttcttttg gttgaaaaca ctcgttttga agatgttgac ggtaagaaag aatctaagaa
    16561 tgacgaagaa cttggtaaat actgggcttc acttggagat ggaatcttcg ttaacgatgc
    16621 atttggtaca gcacaccgtg ctcacgcatc aaacgtaggt atttcagcaa acgttgaaaa
    16681 agctgtagct ggtttccttc ttgaaaacga aattgcttac atccaagaag cagttgaaac
    16741 tccagaacgt ccattcgtag ctattcttgg tggctcaaaa gtttctgata agattggtgt
    16801 tatcgaaaat cttcttgaaa aagctgataa agttcttatc ggtggtggta tgacttacac
    16861 attctacaaa gctcaaggta tcgaaatcgg taactcactt gtagaagaag acaaattgga
    16921 tgttgctaaa gaccttcttg aaaaatcaaa tggtaaattg atcttgccag ttgactcgaa
    16981 agaagcaaac gcatttgctg gttacactga agttcgcgac actgaaggtg aagcagtttc
    17041 agaaggcttc cttggtcttg acatcggtcc taaatcaatc gctaaatttg atgaagcact
    17101 tactggtgct aaaacagttg tttggaacgg acctatgggt gtctttgaaa accctgactt
    17161 ccaagctggt acaatcggtg tcatggacgc tatcgttaaa caaccaggcg ttaaatccat
    17221 catcggtggt ggtgattcag cagctgctgc tatcaacctt ggccgtgctg acaaattctc
    17281 atggatcagt actggcggag gcgctagcat ggaacttctc gagggtaaag tattaccagg
    17341 tttggcagca ttgactgaaa aataatagtc attataatat atagtaaagg gcatgctgat
    17401 gcatgtcttt ttttagttga tcatgtagag ttattgaact ttccctaact tcacttatca
    17461 tttactagtt tttagatata gtggtatttg actgacactg caattttcaa aagtttatga
    17521 cgatttcata tcaattggtt tataaaagat atcctaatca taaataaaac gtttaccaaa
    17581 agggttttat ggattgatat gttaaaatag atagtgaagg gataggtatg aaaacgttaa
    17641 gaaaattatt atctaattac aagtttgata ttaaaaagtt taaattggga atgagaacat
    17701 tgaaaacagg cttatcggtc tttttagttt tattggtttt tcatttattt ggttggaaag
    17761 ggctccaaat tggtgctcta actgctgtat ttagtttaag agaagacttt gataaaagcg
    17821 tgcactttgg cttttctaga attattggta atagtatagg tggcctactc tccttagtat
    17881 tttttgcatt caatgagata tttcatcaag ctttttgggt tactttatta attgttccta
    17941 tttgtaccat gttatgtatc atggttaatg ttgcatgtaa taataaatca ggtattattg
    18001 gggcagtggc tgctcttttg attattacac tgtctattcc aacaggacaa acgtttattt
    18061 atgtgacttc gcgggtattt gaaacatttt gtggcgtctt tgtagctatt ttagttaata
    18121 ctgatgttga acttattaaa aataaatggt ttaacaaaaa acacagcgat gttagataat
    18181 ataacatata tacttgacag gttatttttt tcagcctata ataaggaaga tgaaaggagt
    18241 ttgtcatgaa agaaaaagaa cttagacgct caatggctgt ttttcctatt ggaacggtga
    18301 tgacattaac agatctctct gcgagacaaa ttcgctatta tgaagatcaa ggtttaatta
    18361 agcctgaacg aacgcaaggg aatcggcgta tgttttcctt aaatgacatg gaccgacttt
    18421 tggaaattaa agattttttg tctgagggat taaatattgc agctattaaa cgcgaatatg
    18481 tcgagcgtca aggtaagtta atgcaaaaac aaaaagctct aacagatgca gatgtcagac
    18541 ggatcttaca tgatgaaatg ctgacacaaa gcggtttttc tactccctca cagcatattg
    18601 gtaattttcg tatttaagat atgaattgta taaaatttaa aggagaccta tttaatggca
    18661 atcacagtag ctgacattcg tcatgaagtc aaagaaaaaa atgtaacgtt tcttcgcttg
    18721 atgttcactg atatcatggg cgttatgaaa aatgtggaga ttcctgcaac gaaagaacag
    18781 ttagacaaag tattgtctaa caaggtcatg tttgatggtt catctatcga aggttttgta
    18841 cggatcaatg agtcagatat gtacctttac cccgatttag acacttggat tgtttttccc
    18901 tggggagatg aaaatggagc agttgcaggt ttaatttgtg atatttatac agcagaagga
    18961 aagccttttg caggagatcc tagaggaaat ttaaaaagag ccctgaaaca catgaacgag
    19021 atcggctaca aatcatttaa tcttgggcca gaaccagaat ttttcctttt taagatggat
    19081 gataaaggta atccgacact tgaagttaac gataatggtg gttattttga tttagcgcca
    19141 attgacttag cagacaacac gcgccgtgaa attgtgaata ttttaacgaa aatgggtttt
    19201 gaagtggaag ctagtcatca tgaagtggct gttggtcaac atgagattga ttttaaatat
    19261 gcagatgttt tgaaagcttg tgataatatt caaattttta agctagttgt aaaaacgatt
    19321 gcccgtgaac atggacttta tgctactttt atggctaaac caaaatttgg aatagctgga
    19381 tcagggatgc actgtaacat gtctttgttt gataaccaag gtaataatgc tttttatgat
    19441 gaaactgata agcgaggaat gcagctatca gaagatgctt attatttctt gggaggacta
    19501 atgaagcatg cttataacta cactgctatc actaacccta cagtgaattc ttacaaacga
    19561 ttagttccgg gttatgaggc acctgtttat gtcgcttggg ctggaagtaa tcgttcaccg
    19621 cttatccgtg ttccagcatc acgtggtatg ggaacgcgtt tggagttacg ttcggttgat
    19681 ccgacagcta atccttattt agccttggct gttctcttgg aagctggatt agatggtatc
    19741 attaacaaaa ttgaagctcc agaacccatt gaagctaaca tttataccat gacaatggaa
    19801 gaacgaaatg aagcaggcat tattgatttg ccatcaacgc ttcataatgc cttaaaagct
    19861 cttcaaaaag atgatgtggt acaaaaggca ctaggttacc atatctacac taatttctta
    19921 gaagcaaaac gaattgaatg gtcttcctat gcaactttta tttctcaatg ggaaattgac
    19981 cattatattc ataattatta gacttatcag gacctgctca agttgagtgg gtcttttgta
    20041 tgagctattg tatttgagct agcaagctat tattagctga tcggacacca attgattttc
    20101 cattatagaa aactaaaaac cagtccatgt tctatgagga ctggttttta gtttgataat
    20161 tatctgaact agaactgata tgttaaagat atagacagat agtattaaga aatgagtctt
    20221 atttgatttt agtgcttatc aggtgttaag accatcggaa ttataattgg ttcacgctca
    20281 gtcttttcat acaagaatgg acgaagagca ttgacgatag caccgttaac tgattggatg
    20341 ctagcatcct tattttttaa agcaatacgt atagcgttaa agagcacacg ttggctttcg
    20401 cggatcaagt cacctgactc acgcatataa atgaaaccac gactcagaat atctggtcca
    20461 gctaaaatca tttgtgtgtt aaaatcaaca gttgcaacag ctaagacaac accatcttct
    20521 gacaaatcac ggcggtcccg taaaacggct gctccaatat ccccgatgcc attaccatcc
    20581 acgtagatgt cttgggcatt aaagtgacca gcaatacgcg cactgtcact ggttaaagct
    20641 agaacgtctc cattttccat aataaagata ttttcttttg gaataccaat atccatcgcc
    20701 agtcctgcat gaactttttg catgcgatac tcaccatgta ctggcatgaa atattttggt
    20761 ttaatcaaac taagcatgag cttttgttct tgctgtcctc catgaccaga agtatgaata
    20821 ttattgactt ttccatgaat aacatcaaca ccagcttctt ggatggtatt gattaattta
    20881 ttgacacttg tggtattacc agggattgga cttgatgaga aaatcacagt atcaccaggc
    20941 tgtaaagtta cttgacgatg agcgccgtta gcgatacgag caagtgctgc catagactca
    21001 ccttgactac ctgtacacat aattaaaact tcactagcat gaagattttt aagttcgctt
    21061 ggctcaatga aggtaccttt tggaacttta atatagccaa gttcaatacc gttaacaatt
    21121 gccttttcca tagaacgacc aaaaacggca attttacgtc ccgttttaac agcagcttct
    21181 gcagcctgtt gcaaacggta gatgtttgaa gcgaaggaag caaaaataat acgcccatga
    21241 ataccttcga taatttttaa aatggattgg ccaacaactt tttcagagtt agtaaaggtt
    21301 gggatttcag cattagttga gtctgataat aagcaaagga caccttcttc accaagcgct
    21361 gccatacgtt gtaaatctgc aggatctcct actggcgtga agtcaaattt aaaatcacca
    21421 gtacagataa tcttaccttg aggggtgtgg ataacaatac cgaccggttc tggaatggaa
    21481 tgagtagtct tgaagaaagt gacgctcatg tttttaaaag ttaactcggt gttgtgattg
    21541 atttcgtaaa cagttgcttc acgccaaaga ccatgttctt ccaatttacc acggataaga
    21601 gcaagtgcta aaggtcctgc gtagataggg atattagcct gtttgagaag aaatggaata
    21661 ccaccaatgt ggtcttcgtg accatgtgta ataacaagag ctttgacccg gtctaagtta
    21721 tcgacaatgt aagaatagtc aggaataacg taatcaattc ccaaaagatc atcttctggg
    21781 aatttgatac cggcatcaac gataatgatc tcgtcttgat actcaatacc ataagtattc
    21841 ttcccaatct ctcccagacc accaatggca aacaccccaa cttcattagg ttttaaactg
    21901 atatttgtca tcttagaact ccgttaattc aaaaacaccg gtctcttttt cgtaatcgag
    21961 gtgtttgtca gaaagtagct cgataaattc cacgttataa taggtgttat cttcaacgag
    22021 acgacgagcc ttgatacggc catcgagttc atcagtagca tcaatattaa gatagagtgc
    22081 tttagtactt tcacgacgtg ggctttgatc ctttgtttct tgatagaaaa ctttataaat
    22141 catttgtttt ttaattcctt tcgttatgaa tcaattatcc aaacaataat aaataggtca
    22201 aaaggtaggt gttccatttt gacggtttta tatgttgtca ttattgtgta gtagattaat
    22261 tcctgattct gtgcaattat tataattata ccataaactt agcttttagt aaaaaattta
    22321 ggtacattta tggtatagtc taaatcaaat taagagtcag cctttttgtt tatgattctt
    22381 aatttgtgtt ataattgata ctagaacttg cagtagaaag gcataaaatg aagacacttg
    22441 catttgatac ctcaaataaa accttgtccc ttgctatact tgatgatgag acacttctag
    22501 cagatatgac ccttaacatt cagaaaaatc atagtgttag ccttatgcct gctattgatt
    22561 ttttgatgac ttgtactgat cttaaacctc aagatttaga aagaatagtg gttgcaaaag
    22621 gccctggatc ttacacaggt ttacgagtgg cagttgctac tgcaaaaacg ttagcgtaca
    22681 gtttaaatat tgcattggtc gggatttcga gtctatatgc tttggctgcg tctacttgta
    22741 aacagtatcc aaatactttg gtggtgccat tgattgatgc tagaaggcaa aatgcgtatg
    22801 taggttatta tcggcaagga aaatcagtga tgccacaagc ccatgcttca ctagaagtta
    22861 ttatagaaca attagtagaa gaaggacagc tgatttttgt tggggagact gctccttttg
    22921 ctgagcaaat tcaaaagaaa ctacctcagg cgatactact tccaaccctt ccttctgctt
    22981 acgaatgtgg tcttttgggg caaagtttgg caccagaaaa tgtagacgcc tttgtccctc
    23041 aatatctcaa gagagtggaa gctgaagaaa actggctcaa agataatgag ataaaagatg
    23101 atagtcacta cgttaagcga atctaatatg aaaacagttg aagaacaagc aaaaaatatt
    23161 tatcagcttt tggaaatggt ttatggcacg tctccttgga ctttagaaca agtattaatc
    23221 gatatacggc gggatcaaac agattatttc ctactatatg atcatgataa attgctaggt
    23281 tttttagcta ttcaagattt agctggtgaa gttgaaatga ctcaaattgc tatactacct
    23341 agtcatcaag gacttgggct agtgtctcaa ttgatgacgc atttagatag cattgaaagt
    23401 gacatctttt tagaggttag agaatctaat catagagcac agggtttata tcagaagttt
    23461 ggttttaaat ttattggcaa aagaccagac tactatagaa atcctataga aacagcttta
    23521 ttgatgaaac gggaaggaaa acatgacaga taggtatatt ttagcagttg agagttcttg
    23581 tgatgagacc agtgtagcga ttttaaaaaa cgaaagtacc ctcttaagta atgtcattgc
    23641 aagtcaggtt gagagccaca aacgctttgg tggtgtggtg ccagaagtag ctagtagaca
    23701 ccatgtcgaa gtgattacga cttgctttga ggatgctttg caagaagctg gcatcagtgc
    23761 ttcagattta tcagcagttg cggtaactta tggccctgga cttgttggag ccttgttagt
    23821 tggattagca gctgcgaagg cttttgcttg ggcaaatcat ttacctttga ttccggttaa
    23881 tcatatggca ggccacttaa tggcagcgcg tgaacaaaag cctttagttt atcctttaat
    23941 agcactattg gtttcaggag gacacacaga attggtttat gtcccagagc caggggatta
    24001 tcatattatt ggcgagacgc gtgacgacgc tgttggtgag gcttatgata aagttgggcg
    24061 tgtgatggga ttaacctatc cggcaggacg tgaaattgac cagttggctc ataaaggtca
    24121 agatacttat catttccctc gtgctatgat aacagaagac cacttagaat tttccttttc
    24181 aggactcaag tccgctttta tcaatcttca tcataatgct aagcaaaaag gcgatgaact
    24241 gattctagaa gatttgtgtg catcttttca agcagctgtt ctagatattt tattggccaa
    24301 aacaaaaaaa gctctgagca gataccctgc aaagatgctt gtagtggctg gtggtgtagc
    24361 ggcaaatcaa ggattacgag atagattagc acaagaaatt acacatatag aagttgtgat
    24421 tcctaaacta agactctgtg gagataacgc gggtatgatt gctttagcag cagctattga
    24481 gtatgacaaa cagcattttg ctaatatgag cctaaatgcg aagcctagtt tagcttttga
    24541 ccagtttcca gacagttttg taataaacta gtcacacttg ctagttagta agatttataa
    24601 tggataagaa tctccctttg aaaaaacaac ccggtatctt ggcataccgg gttgtcatga
    24661 tgataagtaa ttggcttcta tggttactaa taattcagat aattacctgc aaaataattg
    24721 tctgcctaag gtgaagtaag cttaccagct agctttagtg acgccaggaa gctgtccttt
    24781 gtgagctaag tcacggaaat tgatacggct aacaccaaac ttacgcatgt aagcatgagg
    24841 acggccgtca attttgtcgc ggttcttcaa gcggtttgga tttgaatcac gaggcaattt
    24901 gcgcagtgat tcataatcgc ccttcgcttt taagtcacga cgaaggtcag cgtactgttc
    24961 aatcagttgg agctgctttt ggtatttagc aatttttgac ttttttgcca ttgctttctc
    25021 cttcttaata tttaataacc tcagagtcgt tatcagcgct ctgaatccac ttaactggta
    25081 tttaactggt taagttgata tataatcatt atacaataaa taaaagcaaa agcaaataaa
    25141 aaaaattaac tagttatctt ttttagccat aatatcaaaa aactccacat ctaagtgtgg
    25201 gagtcaggta ttaataactg tttaaaggtg tttaatgagt gtcgctttag caactttgag
    25261 attgaacttt taagtcaaat aaatcagcag gaacgtagtg tttggttgag accaagatgt
    25321 ctttaccatt gtagagagtt tcttggatta aaataaaagc actattttct gatagagtat
    25381 acttagttgc tgtgtaattg ccagtcttgg tatagccgat ttggttgcag gaatgagaag
    25441 ctttaccaga ttcatagatt ttctcttcta agaaagtaag aaggggctct tcttgattga
    25501 gatttatagc atatttagaa ataacctcaa tagggataaa agataaacta taagcaatag
    25561 ctttattttg gctatgatac cagcgatcaa caataatcac aacaggagtt tcttgtttta
    25621 gggatgctgt aatggcaaca gtgggcactt caatccgata ttccaactca acctttgtga
    25681 tgtcagatga taggcttgca tatatggggt gttgaagata ttcgaaacct tggtgatatt
    25741 tagtttcagg agtcttgagt ataaaatttc cctttcctct gatatttttt atgagatgat
    25801 cctcttggag gagggctagg gatttacgca gtgtcatccg actgacattg agctgtctag
    25861 caagttcagg ttctgatggc agttgcatgc caggactata tgtaccatct tgaataagtt
    25921 gaaaaatagt attatatact tgcacatgtt taagtttttt gagttttttg gttaagtcgt
    25981 tagtagacat atcacttacc tcattaataa tctttagtgg agtttaactt gtctaaaaac
    26041 tattttagca ctaacagtat tccttgatta gaattgtacc catctatagt gttagtatct
    26101 cacactcagg tactttttgt caaaaaagag atgaaaaaca ccttaaaaaa gcgtttacaa
    26161 aatagagtgt gtgtgatact atacaagtgt atcaaaaatt agacaagtaa aatacaggag
    26221 gtttttaaca tgcaaaatta ttcaggtgaa gtcggattgc aatatcacct acagattcgt
    26281 ccaggtgatg taggtcgtta tgttatcatg ccaggtgatc caaaacgttg tgcaaaaatt
    26341 gcagaacatt ttgataatgc agttcttgta gcagacagcc gtgaatatgt tacgtataca
    26401 ggtacattaa acggtgaaaa agttagtgtt acttcaactg gtattggtgg tccatcagcg
    26461 tctattgcga tggaagaatt gaaactttgt ggcgctgata cctttatccg tgttggaaca
    26521 tgtggtggta ttgaccttga tgttaaaggc ggagacatcg ttattgcaac tggagctatc
    26581 cgtatggaag gtaccagtaa agaatatgct ccgattgaat ttcctgctgt agctgacttg
    26641 gaagtgacaa atgctctagt taatgcagct aaaaagcttg gttatacaag tcacgcagga
    26701 gtagttcaat gtaaagatgc attttacgga caacatgagc cagaacgtat gccagttagt
    26761 tatgaattat taaataaatg ggaagcatgg aaacgtctgg gaacaaaagc gtctgaaatg
    26821 gaatctgcag ctctttttgt agcagcaagt catctaggag ttcgttgtgg atcagatttc
    26881 cttgttgttg gtaatcaaga acgcaacgct ttgggtatgg ataacccaat ggctcatgac
    26941 acagaagcag ctattcaagt tgctgttgaa gcactccgca cacttattga aaatgataaa
    27001 tcacaataag cgaggttttg gaagtcatca tgcaatttat ttatagtatt attggtattt
    27061 tattggtatt aggaattgtg tatgcaattt ctttcaatcg taagggtgtt tctctaagtt
    27121 taattggaaa agctcttatc gttcaattca ttattgcgct aatcttagta cgtatcccac
    27181 taggccaaca aattgttagt gttgtttcaa ctggagttac tagcgtaatc aactgtggtc
    27241 aagctggttt aaattttgtg tttgggtcat tagcagatag tggcgcaaaa actggtttta
    27301 ttttcgctat tcaaacgctt ggtaatattg ttttcttatc tgccctagtt agtctacttt
    27361 attatgtagg aatccttgga tttgtagtaa aatggatagg taagggcgtt ggtaaaatta
    27421 tgaaatcctc agaggttgag agttttgttg ctgtagctaa tatgtttctt ggtcaaacag
    27481 acagtccaat cttggttagc aaatacctag gtcgtatgac tgatagtgag ataatggttg
    27541 tgttggtatc aggtatggga agtatgtcag tttctattct tggtggctat attgcattag
    27601 gcattccaat ggaatatctc ttgattgctt caacaatggt tcctattggc agtattctta
    27661 ttgctaaaat cttattgcct caaacagaac ctgttcaaaa aattgatgac attaagatgg
    27721 ataataaagg taataacgcc aatgtgattg atgcaatcgc tgagggtgca agcacaggtg
    27781 cacaaatggc tttctcaatt ggtgctagtt tgattgcctt tgttggttta gtttctttga
    27841 ttaatatgat gttaagtgga ttgggaatcc gcttagaaca aatcttttca tatgtttttg
    27901 ctccatttgg ttttcttatg ggatttgact acaaaaacat tcttctagaa ggaaaccttc
    27961 ttggaagtaa gttgatttta aatgagtttg tttcgttcca acaattgggt cacctaatca
    28021 aatctttaga ttatcgtaca gcattggtag caactatttc actctgtggt tttgctaatt
    28081 tatcaagttt aggtatttgt gtttcaggta ttgctgttct ttgcccggag aaacgtagca
    28141 ccctagctcg acttgttttc cgtgcaatga ttggtggtat tgctgtaagt atgcttagcg
    28201 cctttatcgt cggtattgta actctattct aagcgttgac aaaagaaaga aggatagtaa
    28261 cgtggaagta aaagatattt taaaaacggt agaccatact ttgctagcaa caacagcaac
    28321 gtggccagaa atccaaacaa ttttagatga tgccatggct tatgaaacag cttcagcatg
    28381 tattccagct tcttacgtca aaaaagcagc agaatacgtt tcaggtaaat tagctatttg
    28441 tactgttatt gggttcccaa atggctatag tacaactgcg gcgaaggttt ttgaatgtca
    28501 agatgctatt caaaatggtg ctgatgaaat tgacatggtc attaatttga cagacgttaa
    28561 aaatggggat tttgatactg ttgaagaaga aattcgtcaa atcaaagcta aatgtcaaga
    28621 ccatatctta aaagttatcg ttgagacatg tcaattaact aaagaagaac ttatcgaact
    28681 ttgtggagtt gtcacacgtt caggtgcaga ctttattaaa acctctactg gtttttcgac
    28741 agcaggtgct acatttgaag atgttgaagt gatggcaaaa tatgtcggcg aaggtgttaa
    28801 aattaaggca gcaggtggaa tctcatcatt ggaagatgct aaaacattta ttgctttagg
    28861 agcttcacgc ttgggtacta gccgtatcat caagattgtt aagaacgaag ctacaaaaac
    28921 cgatagctat taacttaatc ataccgattt agcttgagac taaaacaaaa aactcatata
    28981 ataggagtta aaaagcctac tatcttagtg ataataggct tttttagcta tgaagacttc
    29041 cctgcgatcc atcctgaaca aagagctgag gtaatattaa accctccggt gtgagcatta
    29101 atatctaaga cctctccagc gaaatacagg ccaggaactt tcttgctttc caaggtttta
    29161 gggttgattt cttttaaatc tacgcctcct ttggtcacaa atgatttagc caaagacatt
    29221 tttcctgtaa tgggtatctg gaggtgtttg agtttatcaa gcaattcctt ttcttgtttt
    29281 ggagagagtt gtttgacctt ttcggggtaa tcttctgata aaaaatcagc tactcgttca
    29341 ggcagtaggc ctttaagagc atttttgatg tttttatcac gttgatcact cagataagcg
    29401 gttaagtcat ctgttgataa gtgtggcaaa aagtccagct ctgcaatttc tccacctttc
    29461 acaaaagagg acagacgaag agctgcaggt cctgaaaggc caaagtgggt gaagagtaag
    29521 tcgtgtgtga tgacgtgttt gtcataacta agagtaacgt cgtctaggga aataccttgc
    29581 aagactttgt gaggaaaatc agttaacaga gggctctcag cagcttctaa atcagtcacg
    29641 gtcagtttaa aatgccgtgc aatatcatgt ccaaaacctg ttgaacccgt tgaagggtag
    29701 gacttgcctc ctgtggtcac aatcaatttt tggcaggtga aagtctggtc tgcagatttg
    29761 aggtagaaga ggtcatcttg ttttttaacg gaaaccactt cagtgctggt tagcacctga
    29821 cccccaagag ccttgatttt tttctccaga gcatcaatga ttgtccttga tttatctgtt
    29881 gtggggaaca tccgtccatg gtcttcttct ttgagtttga cgccgttttc ctcgaaaaag
    29941 gcaatgatgt catggttgtc aaactgggaa aaaacactat ataaaaagcg gccatttcca
    30001 ggaatgccag ccataaggtc atcaaggtta ccactattag tgacattaca gcgtccacca
    30061 ccggttcccg ctaatttttt acctaagcgg cgattttttt caattaagag agttttatag
    30121 ccatagtagc tgctggagat ggcggccatc ataccagcag ggccacctcc aataataatc
    30181 gtatcgtatt gagtcatagc cttattttag cataaaagcg ggggggttaa tagtcaggta
    30241 aatgaactaa cctggcatac cgttttttta cgcatttaaa caatgcctcc atgacatcaa
    30301 aaagctagaa aaatagtcca gatgattaaa attatctttg tatgaaaacg gttgcttttt
    30361 tatttaattc atgctattgt attactaaag aatgaagtaa tcattaagtt cttttgaaat
    30421 tttttaaaaa ttaaataatt ttattaaagg agaatagtat aaaaaaagat ttaatagcaa
    30481 agcgataact ttgcttgctg taagctcttt aagtttggga tttacggccg taactagtgt
    30541 tgtcagtgcg gcaacagcac atccagctcc atctccaatt attgatgaat ggaattatgg
    30601 agtaagtgac aactatggtt attctaatta ttatgttaaa tctccaaaca atattggttc
    30661 aaaatcttcg ataactaatt attggggatc cattaaggca tctgattctc aaaaatacgg
    30721 gtgggcactg tcaagttcaa aaaaaagctt ggaatgatat tcggttgaat gcacattgga
    30781 attactttaa tttttagaaa tggtatatgc aagctaaaga cccaataatt attatagggt
    30841 cttttataat ataggaagtt gtttatgaaa ttaaaattat ctgtcattgg attattcttt
    30901 tgcttaattg ctgcgatagg tgttatcagt attagtgata ctcaaaaacc agtaccttta
    30961 ccaattgatg gtgccttttc aatccaagga aaaagtagcc tttctagtga cgaagtttac
    31021 aaaaagatta gtaatctatc aaaaacgaaa aacgttaata tttacaagcc tatagttcgt
    31081 aactcaggtc agttgactta tatcaatttt aaaaatacaa attatgaaca attaaaacct
    31141 gcaccgataa caggcatgta ttatacctta ggtaaaatag attcaagtag cttaaaggta
    31201 cttacagctt caggtttgaa acttatttat gcagcctatc cttggtatat aggggggatt
    31261 ttacaatttg atgggacttt aaggttgtta ttgatgctat caatttactt aacattatta
    31321 gttgttttat ttgttgttag aacgaggcag attaaagaag gagtgataag acattcttta
    31381 ggattgccta tatataactt aagaagagat tatgtcattt cttttacttt tgaattggtt
    31441 atggctggtt tgttaatgat tgcctacagc tatttttggg gaagtggcct ctttacttac
    31501 agttctaagt tatttttctc tctaatttta actaatctta taatattcca gattgttgac
    31561 attatcactt ttattttatt ttggctaact attagggttg agaaacctat tgaaattata
    31621 aaaaataaag caaaaaatag ttttcttttt attgtatggc ttgtaattat ttctattata
    31681 ataatcgtct caggaatctt tttacaagaa acaaaggcta gtcaatcaag gataaataga
    31741 cagataagtc aactatcccc atggaacaaa gtaagaaact ggaaaagact agagttgttg
    31801 gggattgaaa atggctctat taataatggg gaaataaatg agccagaatc acaatatata
    31861 cagatagcga cagccttaaa aaaattagat tttatatata tcaaaccctc ttcagtatat
    31921 attccagatt acatgaaaaa tactaacttt gcagaagatt ttttcaaaaa attaaataat
    31981 gatggtataa cggatccaga agtaaataaa gagatgattt atatcaataa atcgggcgct
    32041 aatattcaaa ataaagtcaa tggaacagac tatcagctgt tagataataa ggtagcaaca
    32101 atctatattc ctgataaatt taaagagaaa aagaaatcaa ttgaaaatac cgttgtggca
    32161 gaacaattta ctggaactaa gtatacaaaa gaaaaccttg cagtgcagat aattcctaat
    32221 gagaaaaaaa ttttttattt taatgagaat ggaaacgagc atgatgaaaa taaagaagcc
    32281 tcacctatgg caaatgtaac agatagtaaa ggtaatatag tcgttgtgtt agatactgat
    32341 aaaatggtag caagcaaaga tttttctttg gctagcaata tagtaaatag ctctcttttt
    32401 agtcctgaag caataaaaaa aattaatgac ctgagtctac atttaaattt ttcaattaat
    32461 ccagtagatg tttaccaact tgtaaaactt aatattcaat ccttaaagca ccaaattttc
    32521 ctttcgaaag ttttgcagaa a
//
LOCUS       DAUNLR010000017        29795 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUNLR010000017 DAUNLR010000000
VERSION     DAUNLR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29795
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.017"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            166..1524
                     /locus_tag="VLL59_000792"
     CDS             166..1524
                     /locus_tag="VLL59_000792"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HER6508930.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGNEFLATFDCLRG
                     DA"
     gene            1524..2606
                     /locus_tag="VLL59_000793"
     CDS             1524..2606
                     /locus_tag="VLL59_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HER6508931.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            2607..3755
                     /locus_tag="VLL59_000794"
     CDS             2607..3755
                     /locus_tag="VLL59_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HER6508932.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKPKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMYDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQTPPSPETVLEQAHG"
     gene            3967..5331
                     /gene="ftsA"
                     /locus_tag="VLL59_000795"
     CDS             3967..5331
                     /gene="ftsA"
                     /locus_tag="VLL59_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HER6508933.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            5355..6674
                     /gene="ftsZ"
                     /locus_tag="VLL59_000796"
     CDS             5355..6674
                     /gene="ftsZ"
                     /locus_tag="VLL59_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HER6508934.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            6677..7348
                     /locus_tag="VLL59_000797"
     CDS             6677..7348
                     /locus_tag="VLL59_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HER6508935.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            7360..8016
                     /locus_tag="VLL59_000798"
     CDS             7360..8016
                     /locus_tag="VLL59_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HER6508936.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSSIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            8021..8275
                     /locus_tag="VLL59_000799"
     CDS             8021..8275
                     /locus_tag="VLL59_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HER6508937.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            8275..9066
                     /locus_tag="VLL59_000800"
     CDS             8275..9066
                     /locus_tag="VLL59_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HER6508938.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRVA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            9076..9834
                     /locus_tag="VLL59_000801"
     CDS             9076..9834
                     /locus_tag="VLL59_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HER6508939.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            10107..12908
                     /locus_tag="VLL59_000802"
     CDS             10107..12908
                     /locus_tag="VLL59_000802"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HER6508940.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLTEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKVIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(13173..13475)
                     /locus_tag="VLL59_000803"
     CDS             complement(13173..13475)
                     /locus_tag="VLL59_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HER6508941.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(13526..13981)
                     /locus_tag="VLL59_000804"
     CDS             complement(13526..13981)
                     /locus_tag="VLL59_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HER6508942.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(14109..16391)
                     /locus_tag="VLL59_000805"
     CDS             complement(14109..16391)
                     /locus_tag="VLL59_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HER6508943.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKIDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            16689..16919
                     /locus_tag="VLL59_000806"
     CDS             16689..16919
                     /locus_tag="VLL59_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HER6508944.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            17046..17732
                     /locus_tag="VLL59_000807"
     CDS             17046..17732
                     /locus_tag="VLL59_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HER6508945.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            17732..18466
                     /locus_tag="VLL59_000808"
     CDS             17732..18466
                     /locus_tag="VLL59_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HER6508946.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            18615..20024
                     /locus_tag="VLL59_000809"
     CDS             18615..20024
                     /locus_tag="VLL59_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HER6508947.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATSDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEYVPEKYLHEPWKMPKNLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKVKIE"
     gene            20202..21896
                     /locus_tag="VLL59_000810"
     CDS             20202..21896
                     /locus_tag="VLL59_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HER6508948.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSVTKLDAIEAACRTKINQVN"
     gene            22104..22958
                     /locus_tag="VLL59_000811"
     CDS             22104..22958
                     /locus_tag="VLL59_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HER6508949.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQNKGIVPGLVVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            23111..24451
                     /locus_tag="VLL59_000812"
     CDS             23111..24451
                     /locus_tag="VLL59_000812"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HER6508950.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKIDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHSLANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            24429..24644
                     /locus_tag="VLL59_000813"
     CDS             24429..24644
                     /locus_tag="VLL59_000813"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HER6508951.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            24644..25516
                     /locus_tag="VLL59_000814"
     CDS             24644..25516
                     /locus_tag="VLL59_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HER6508952.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            25509..26336
                     /locus_tag="VLL59_000815"
     CDS             25509..26336
                     /locus_tag="VLL59_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HER6508953.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            26323..26793
                     /locus_tag="VLL59_000816"
     CDS             26323..26793
                     /locus_tag="VLL59_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HER6508954.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            26815..28476
                     /gene="recN"
                     /locus_tag="VLL59_000817"
     CDS             26815..28476
                     /gene="recN"
                     /locus_tag="VLL59_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HER6508955.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLESELKALEKQLVAAATNLSERRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            28648..29622
                     /locus_tag="VLL59_000818"
     CDS             28648..29622
                     /locus_tag="VLL59_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HER6508956.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFNDDSFISQNETDKMFENLTDDR
                     LLNELNELDELDELDELDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPH
                     LEAELPKPHLRSLSDTALRSGEIRGHLDNKLDTLSVTATKLALTMAQKFDLTTHVYSI
                     GESFSEVLAAHYEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVP
                     YNRKLGMAVAKRKIALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
BASE COUNT         9387 a         5112 c         6373 g         8923 t
ORIGIN      
        1 tttacttaaa aaaacgtacc aataatctca caaatatggg catgatattt gtatattgga
       61 aacggattct aattctaaac tcaagaacgg tatttttaaa atgttgaaaa agcatctaaa
      121 taaaggtaaa atagaaatca aatagaatgg atagtgtgag cttagatgaa agtgataagt
      181 aattttcaaa acaaaaaaat attaatattg gggttagcca aatcgggcga agcagcagca
      241 aaattattga ccaaacttgg tgctttagtg actgttaatg atagtaaacc atttgaccaa
      301 aatccagcgg cacaagcctt gttggaagag gggattaagg tcatttgtgg tagccaccca
      361 gtagaattat tagatgagga ctttgagtac atggttaaaa accctgggat tccttatgat
      421 aatcctatgg ttaaacgcgc ccttgcaaag gaaattccca tcttgactga agtagaattg
      481 gcttatttcg tatctgaagc gcctattatc gggattacag gatcaaacgg gaagacaacc
      541 acaacgacaa tgattgccga tgttttgaat gctggcgggc aatctgcact cttatctgga
      601 aacattggtt atcctgcttc aaaagttgtt caaaaagcaa ttgctggtga tactttggtg
      661 atggaattgt cctcttttca attagtggga gtgaatgctt ttcgccctca tattgctgtc
      721 atcactaatt taatgccgac tcacctggac tatcatggca gttttgagga ttatgttgct
      781 gctaaatgga tgattcaagc tcagatgaca gaatcagact accttatttt aaatgctaat
      841 caagagattt cagcaactct agctaagacc accaaagcaa cagtgattcc tttttcaact
      901 caaaaagtgg ttgatggagc ttatctgaag gatggaatac tctattttaa agaacaagcg
      961 attatagctg ccactgactt aggtgtccca ggtagccaca acattgaaaa tgccctagca
     1021 actattgcag ttgccaagtt atctggtatt gctgatgata ttattgccca gtgcctttca
     1081 cattttggag gcgttaaaca tcgtttgcaa cgggttggtc aaatcaaaga tattaccttc
     1141 tacaatgaca gtaagtcaac caatatttta gccactcaaa aggctttatc aggttttgat
     1201 aacagtcgct tgattttgat tgctggcggt ctagatcgtg gcaatgaatt tgacgatttg
     1261 gtgccagacc ttttaggact taagcagatg attattttgg gagaatccgc agagcgtatg
     1321 aagcgagctg ctaacaaagc agaggtctct tatcttgaag ctagaaatgt ggcagaagca
     1381 acagagcttg cttttaagct ggcccaaaca ggcgatacta tcttgcttag cccagccaat
     1441 gctagctggg atatgtatcc taattttgag gttcgcggga atgaattttt ggcaaccttt
     1501 gattgtttaa gaggagatgc ctaatgccta agaagatttt atttacaggt ggtggaactg
     1561 taggtcatgt caccttgaac ctcattctca taccaaaatt tatcaaggac ggttgggaag
     1621 tacattatat tggtgataaa aatggcattg aacatacaga aattgaaaag tcaggccttg
     1681 acgtgacctt tcatgctatc gcgacaggca agcttagacg ctatttttca tggcaaaatc
     1741 tagctgatgt ttttaaggtt gcacttggcc tcctacagtc tctctttatt gttgccaagc
     1801 ttcgccctca agcccttttt tccaaaggtg gttttgtctc agtaccgcca gttgtggctg
     1861 ctaaattgct tggtaaacca gtctttattc atgaatcaga tcggtcaatg ggactagcaa
     1921 acaagattgc ctacaaattt gcaactacca tgtataccac ttttgagcag gaagaccagt
     1981 tgtctaaagt taaacacctt ggagcggtga caaaggtttt caaagatgcc aaccaaatgc
     2041 ctgaatcaac tcagttagag gcggtgaaag agtattttag tagagaccta aaaaccctct
     2101 tgtttattgg tggttcggca ggggcgcatg tgtttaatca gtttattagt gatcatccag
     2161 aattgaagca acgttataat atcatcaata ttacaggaga ccctcacctt aatgaattga
     2221 gttctcatct gtatcgagta gattatgtta ccgatctcta tcaacctttg atggcgatgg
     2281 ctgaccttgt agtgacaaga gggggctcta atacactttt tgagctactg gcaatggcta
     2341 agctacacct catcgttcct cttggtaaag aagctagccg tggcgatcag ttagaaaatg
     2401 ccacttattt tgagaagagg ggctacgcta aacaattaca ggaacctgat ttaactttgc
     2461 ataattttga tcaggcaatg gctgatttgt ttgaacatca ggctgattat gaggctacta
     2521 tgttggcaac taaggagatt cagtcaccgg acttctttta tgaccttttg agagctgata
     2581 ttagctccgc gattaaggag aagtaaatgg caaaagataa agagaaacaa agtgatgaca
     2641 agctcgtttt gacagagtgg caaaagcgta acattgaatt tttaaagaaa aagaagcagc
     2701 aagctgagga agaaaaaaaa ctcaaagaga aattattgag tgataaaaaa gcgcagcagc
     2761 aagctcaaaa tgcttctgaa gcagttgagc ttaaaactga tgagaaaact gatagtcagg
     2821 aaattgagtc agaaacgacg tcaaaaccta aaaaacccaa aaaagttaga caacccaagg
     2881 aaaaaagcgc gacacaaatc gcttttcaaa aatccttgcc tgttcttttg ggggcgctct
     2941 tacttatggc ggtgtctatt tttatgatca ctccttatag caaaaagaaa gagttttctg
     3001 taagaggaaa ccatcaaacg aaccttgacg aattaatcaa agctagcaaa gtcaaagcat
     3061 ctgactattg gttaacgttg ttaacttcgc ctggtcagta tgaacgaccg attcttcgta
     3121 ctattccatg ggtgaaatct gtacatctct cttaccaatt tcctaatcac tttctattta
     3181 acgttattga atttgaaatc atcgcttatg cacaagtcga aaacggtttt cagcctattt
     3241 tggagaatgg aaaacgtgtg gacaaggtca gggcatcaga actaccgaaa tctttcttga
     3301 ttcttaattt aaaagatgag aaagcgatcc aacagttagt taagcaattg acgacattac
     3361 ctaaaaaatt agtcaagaat atcaagtcag tgtctcttgc aaattccaaa acgacagcgg
     3421 atttactact tattgaaatg tatgacggta atgtagttag agtaccgcag tcacaactca
     3481 cattgaaact tccctattat caaaaattga aaaaaaacct tgaaaatgat agtatagtgg
     3541 atatggaagt tggaatttat actacaacac aggagattga aaatcaacct gaagttcctc
     3601 ttacgccaga acaaaacgca gctgataaag aaggagataa gcctggtgaa catcaggaac
     3661 agacagacaa tgattcagaa acgccagcaa atcagagtag tcctcagcaa acaccaccat
     3721 ccccagaaac ggtcctcgaa caggcccatg ggtagctaat atctaagttg aaaaagcaat
     3781 gaaaacgtta gaaattcaac gattctaacc cataatgaat tgcctaaaaa aaattaagtt
     3841 tatataacaa aaaacgtaaa atgataacat tttacgtttt tttatggtat aatattttct
     3901 gaatgattct gttttttagc agtttttaga atagcaaaag tttggaaagt aagtgaggtc
     3961 aagtgaatgg ctagaaatgg cttttttact ggtttggaca ttggaacaag ctcgataaaa
     4021 gttttagtag cagaatttat ttctggtgag atgaacgtca ttggtgttag taatgttcca
     4081 agtaccggcg taaaagatgg cataataatc gatatagagg cagctgcgac tgccatcaaa
     4141 actgcggtag aacaagcaga agaaaaagca gggatgacaa ttgaaaaggt taatgttggg
     4201 ctaccggcaa accttcttca aattgaacca acacaaggaa tgattcctgt cccaagtgag
     4261 tctaaagaga taaaagatga ggatgttgat agcgttgtta aatcggcttt aacaaaaagt
     4321 atcacaccag aacgagaggt tatctcttta gttccagaag agttcattgt ggatggcttt
     4381 cagggcattc gagatccacg tggtatgatg gggattagat tagagatgcg cgggcttatt
     4441 tatactggac caagcaccat tttacataat ctgcgtaaaa cggtagaaag agcaggcatt
     4501 aaagttgaaa acatcattat ttctccgtta gctatggcta aaaccatttt aaacgaaggt
     4561 gagcgcgagt ttggagctac tgtaattgat atgggaggtg gacagacaac tgtcgcttct
     4621 atgcgagcac aagaattgca gtataccaat atatatgctg aaggcggcga atacattact
     4681 aaagatatat caaaagtatt aaaaacgtct ttggctattg cagaagcact taagtttaat
     4741 tttggtcaag cggagatatc agaagctagt ataactgaaa cagtaaaagt tgatgtggta
     4801 ggtagtgaag agcctgttga ggtaactgaa cgttatttat ctgaaattat ttcagcgcgt
     4861 attcgtcata ttttagatcg tgtgaagcaa gatttggaaa gaggtcgttt actagactta
     4921 ccaggaggca ttgttttgat tggtggcggt gcaatcatgc ctggagtggt agaaattgca
     4981 caagaaatct ttggagtaac tgtaaagctc catgttccaa atcaagtcgg tattagaaat
     5041 ccaatgtttt caaacgttat cagtttggta gaatatgttg gtatgatgtc tgaagtagac
     5101 gttttagcac aaactgcagt ttcaggagaa gaacttttgc gacgcaagcc tatcgatttc
     5161 agtggtcaag aatcttattt accagattat gatgattcaa gaagaccaga atcgaccatt
     5221 ggctatgaac aacaagcgtc acaaacagca tatgattcac aagttccgag tgatcctaaa
     5281 caaaaaattt cagaacgtgt tcgtggcata tttgggagta tgtttgatta aaagtaataa
     5341 agtgaggaga taaaatggca ttttcatttg atactgcatc aattcaaggt gcaattataa
     5401 aagtaattgg agtcggcgga ggtggcggaa atgccattaa tcgtatgatt gatgaaggtg
     5461 ttgctggtgt cgagttcatc gcagcaaata cagacattca ggcattaagc tcatcaaaag
     5521 ctgaaacggt tattcaacta ggccctaaat taactcgtgg acttggtgct ggaggacaac
     5581 ctgaagtagg acgtaaagct gctgaagaaa gcgaagaaat tttaacagaa gctcttacag
     5641 gagcggatat ggtatttatt actgccggta tgggtggtgg ctctgggaca ggggctgcac
     5701 cggttattgc tcgtatcgct aagagtttgg gagccttgac agtagctgtt gttactcgcc
     5761 cgtttggttt tgaaggtaac aaacgtggta attttgctat tgaaggtatc gaagaactcc
     5821 gtgaacaagt tgatactttg ttaattattt caaataataa ccttcttgag attgttgata
     5881 aaaagacacc tttattagaa gcacttagtg aagctgataa tgttttacgt cagggagttc
     5941 aagggataac cgacttaatt actagtcctg gccttatcaa tctcgatttt gccgacgtga
     6001 aaacagttat ggcaaataaa gggaatgcct taatggggat tgggattggt tctggagaag
     6061 agcgcattgt tgaggcggcg cgtaaggcaa tctattcacc cctattagaa acgactattg
     6121 atggtgcaca agacgttatt gtgaacgtta caggaggtct cgacatgaca ctcacagaag
     6181 ctgaagaagc ctctgaaatt gttgggcaag ctgctggtca aggcgttaac atttggttag
     6241 gaacatctat tgatgatact atgaaagatg acatccgtgt gactgttgta gcaactggag
     6301 tgcgccaaga aaaagccgag caagtttcag gttttcgtca gcctaggact tttacccaaa
     6361 ccaacgcgca gcaagtagca ggtgcacaat atgcatcaga tcaagcaaaa cagtcggttc
     6421 aaccagggtt tgatcgtcgc tcaaattttg attttgacat gggggagtct cgcgagatac
     6481 caagtgcaca aaaggtaatt tctaatcata atcaaaatca aggttcagct tttggaaatt
     6541 gggatttgag acgtgataat atttctcgtc caacagaagg tgaattggat aaccatctta
     6601 atatgtcaac gttctcagct aacgatgaca gtgatgatga attagaaacg cctccattct
     6661 ttaaaaaccg ttaataatgg atttactgac aaataaaaag aaaatttttg agactatccg
     6721 cttatctaca gaggcagcaa ataggactaa tgatagtgtt tcagttattg ctgtaacaaa
     6781 atatgtggat agtacaattg caggtcagct tatcgaagca ggaattgagc acattgccga
     6841 aaaccgtgtt gataaatttc ttgaaaagta tgatgcgtta aagtatatgc cagtaaagtg
     6901 gcatttaatt ggtaccttac aacgtcgtaa agtcaaggaa gttatcaatt atgttgatta
     6961 ttttcacgct ctagattctg tgagattagc tttggaaatc aacaagagag ctgaccatcc
     7021 tgtgaagtgt tttctacaag ttaatatttc taaagaagag agtaaacatg gttttaacat
     7081 ttctgagatt gatgaagcga ttgaagaaat aggtaagatg gagaagatac agttagttgg
     7141 tttaatgact atggcaccag caaatgccag taaagaaagt attataacta tttttcgaca
     7201 agcaaatcaa ttaagaaaaa acttgcagtt aaaaaaaaga aagaatatgc cttttacaga
     7261 attgagcatg ggcatgagta acgattatcc aattgctatt caagaaggct caacttttat
     7321 tcggattggt agagctttct ttcactaatg gagaataaga tggcttttaa agatacattt
     7381 aacaagatga tttcttattt tgacacggat gaggttaacg aagttgaaga agatgttgca
     7441 gcatcaactg ataacgttat tccaagatca caacaatcag tcagagcaag tagtcatcca
     7501 aaacaagaac ctagaaacaa tcacgtacaa caagatcatc aagcgagatc ccaagaacag
     7561 acaaggtcac aaatgcatcc aaaacatggt acttctgaac gctattatca gcagtctcag
     7621 ccaaaagaag gccatgaaat ggttgacaga agaaaacgga tgagcacttc tagtattgca
     7681 aatcgccgtg agcagtatca acaatcaact tgttcagatc aaacaactat tgccttaaag
     7741 tatcctcgta aatatgagga tgctcaagaa attgtggatc ttttaatagt taatgaatgc
     7801 gttttgattg attttcagtt tatgctagat gctcaggcta gacggtgttt agattttatt
     7861 gatggtgcta gtaaagtgct ctatggtagc ttacaaaagg tcggctcttc aatgtactta
     7921 ctggctccgt caaatgtatc cgtcaatata gaagaaatga ctatcccaca tactacacaa
     7981 gatattggct ttgattttga tatgaaaagg cggtaaataa atgatattaa tactatctat
     8041 tcttcttcgt ctgatcaaag tttacactta tttattgatt gcttacgcat taatgtcatg
     8101 gtttcctggg gcatatgatt caaaaattgg gcgtttgatt agtggtatcg ttgaaccaat
     8161 tttaaaacct tttagagcat ttaatttaca atttgccggt cttgacttca ctatttttgt
     8221 cgtcattatt agtttgaatt ttttagctca agttttggtc cgtgtgttta tttaatggtt
     8281 agtcatagta agatttatca gcattttcac caagaagaat atccttttat tgatagaatg
     8341 tctgatatga ttaatagagt tgaagattac tatcttttag aagttactga gtttttaaat
     8401 cctagagaag tgatgatttt aaaaagtttg attgctttaa cagatctaaa aatgttcgta
     8461 tcaacagatt actacccaag cgaatatggt cgtgtcatta ttgcacctgg ttactatgac
     8521 ttagaacaaa gtgattttca aatagcttta gtagagataa gttatcaggc aaagtttaat
     8581 cagttgacac atagtcaaat tttaggaact ttaattaatg aattaggagt aaagcgaaat
     8641 ttatttggag atgtttttgt tgaaatggga tatgcccagc tcatgattaa gcgggagtta
     8701 ttggattatt ttttaggaac aattactaaa atagctaaaa ctagtgtgaa attaagagaa
     8761 gttaactttg atcagttaat taggtctatt gataacagcc agaccctgga tattctagtt
     8821 tctagttttc gattagatgg tgtagttgct actatcttaa aaaaatctcg aacgcaagtt
     8881 atagcattaa ttgaagcaaa taagattaag gtaaactatc gagttgctaa taaagcttca
     8941 gataatctag tcatagggga tatggtgagt atcagaggtc acgggcgttt tactctttta
     9001 gcagataatg gagtgaccaa acatggcaaa caaaaaataa cactaagtaa aatgatacat
     9061 aaataaggag atacaatggc acttacaacg ctagaaatta aagataaaac ttttaagaca
     9121 aaattccgag gatactgtga agaagaagtc aatgaattcc ttgatattgt tgttgatgat
     9181 tacgaagctc ttgtacgtaa aaatcgtgat aacgaagcaa gaattaaaga tcttgaagaa
     9241 aaattatctt actttgatga aatgaaagag tcacttagcc agtctgtaat cttagctcaa
     9301 gaaacagctg aaaaagtgaa agcaacggct aatgcggaag caacaaactt ggttagtaaa
     9361 gcgacttatg atgctcagca tttattagat gaatctaaag ctaaagccaa tcaaatgttg
     9421 cgtgatgcaa ctgatgaggc taagcgagtt gcgattgaaa cagaagaact aaagcgtcaa
     9481 acacgtgtgt tccaccaacg tttaatctca tctattgagt cacaattaag cttatcaaat
     9541 tcacctgaat gggatgaact gctacaaccg actgcaatct atcttcaaaa ttctgacgat
     9601 gcttttaagg aagtcgtgaa gaccgttctt aatgaagaca ttcctgaatc tgatgatagt
     9661 gcctcttttg atgcaacacg tcagtttact ccagaagagt tagaagaatt gcaacgtcgt
     9721 gttgatgaaa gcaataagga gttagaggct taccaacttg actctcaatc tgattctacg
     9781 actgagccag aggtaaatct cagtgaaaca caaacgttta aattaaatat ctaaataaag
     9841 aaaaacaaga tgatttgctt ataatcacag caagcgggag atgatgagag tctcgtattc
     9901 cctaagtatt atcattatca ttttctaaaa ttttcgctga actacagtaa gcgaggaggt
     9961 ttgttcacct tacgagcaaa gagggagcgg taagtcttat gatatattat cgctctgaac
    10021 taaggtggta ccacgagctt tcgtcctttt tgagacgagg cttttttcgt tatagtcgca
    10081 agtttgttta aaaggagttt gaaataatga aattaaaaga gacacttaat ctaggaaaaa
    10141 cagcctttcc aatgcgcgca ggtcttccta ataaagaacc acaatggcaa gcagcttggg
    10201 aacaagcaga gctttacaaa aaacgtcaag aattgaatgc aggtaagcct gcctttcatc
    10261 ttcatgatgg acctccatac gctaacggca atattcacgt tgggcatgcc cttaataaaa
    10321 tttcaaaaga tatcattgtg cgttctaagt ccatgtctgg ctttcaagcg ccttatgtac
    10381 ctggttggga cacacacggc cttccaatcg aacaagtctt ggctaagcaa ggaatcaaac
    10441 gtaaggagat ggatttagca gaataccttg agatgtgtcg tcaatacgct ttaagtcagg
    10501 ttgataaaca gcgagatgat ttcaaacggt taggtgtttc ggcagactgg gaaaatcctt
    10561 atgtcacttt ggacccacag tttgaagctg atcaaattcg tgtttttgga gcgatggctg
    10621 aaaaaggtta catctatcgt ggtgctaaac ctgtttattg gtcatggtct tcagaatcgg
    10681 ccttggcaga agctgaaatt gaataccatg acatcgattc aacctcttta tactacgcca
    10741 ataaagttaa agatggtaaa ggcatccttg atactaatac gtatatcgtt gtttggacca
    10801 caacaccatt taccgttaca gcatcacgcg gtttgactgt tgggcctgat atggattatc
    10861 ttgtggtgaa acctgctggt tcagaccgtc aatatgttgt ggcagaaggt cttttggata
    10921 gccttgctgg aaaatttggc tgggaatctt ttgaaacttt agccagccat aaaggagctg
    10981 atttagagta cattgtgaca gaacacccat gggatactga cgtagaagaa ttggttatcc
    11041 ttggtgacca tgttaccctt gagtcaggga cagggattgt ccacacggcg ccaggttttg
    11101 gtgaagatga ctacaatgtt gggacaaaat ataaactgga agttgctgtg actgttgatg
    11161 aacgtggcct aatgatggaa aatgcaggtc cagatttcca tggacaattt tataacaagg
    11221 taacgccgat tgtcattgat aaacttggtg atcttttatt ggcacaagaa gtgatcaatc
    11281 actcttatcc atttgactgg cggacgaaaa aaccaatcat ctggcgtgct gtaccgcaat
    11341 ggtttgcttc tgtttctgat ttccgtcaag atattttgga tgaaattgaa aaaacaacct
    11401 tccatccatc atggggtgaa acacgccttt acaatatgat tcgtgatcgt ggcgactggg
    11461 ttatttctcg tcaacgtgct tggggagttc cgcttcctat cttctatgcc gaagatggca
    11521 cagctattat gactaaagaa gtgacagatc atgtggctga tttgttccaa gaaaatggat
    11581 caatcatttg gtggcaaaaa gaagctaaag acctattacc agagggcttc actcatccag
    11641 ggtcaccaaa tggcgagttt acaaaagaaa ctgatatcat ggacgtttgg tttgactctg
    11701 gttcttcttg gaatggagtc atgaatgcta gagaaaatct ttcctaccca gcggatctct
    11761 acttagaagg ctctgaccag tatcgtggtt ggttcaattc atccttaatt acatctgtgg
    11821 ctgttaatgg gcatgctcca tataaggcta ttttatcgca aggctttgtt cttgatggta
    11881 agggcgaaaa aatgtctaaa tcaaaaggca atatcatttc tccaaatgat gtggctaaac
    11941 aatatggtgc agatattctt cgactttggg tagcttctgt ggataccgac aatgatgtcc
    12001 gtgtttctat ggagatcctt ggtcaagtct ctgaaaccta ccgtaaaatc cgtaacaccc
    12061 ttcgtttctt gattgctaat acatctgatt tcaaccctgc tacggataca gtagcttatg
    12121 cagacttagg agctgttgat aagtacatga caattgtctt taatcagttg gtagcaacga
    12181 ttactgacgc ttatgagcgt tatgacttta tggctattta caaagcagtg gtgaactttg
    12241 ttacggttga tttatcagcc ttctatcttg attttgctaa agacgttgtc tatattgaag
    12301 ctgccaatag cttagaacgt cgtcgcatgc agacagtctt ctatgatatc ttggttaaga
    12361 ttaccaagtt attgacgcca atcttgcctc acactactga agaaatctgg tcttatctag
    12421 agcatgagtc agaagcattt gttcaattga cagaaatgcc tgtggcagaa accttctcag
    12481 ctcaagagga tattttagaa gcttggtcag ctttcatgac tttgcgtacc caagctcaaa
    12541 aagctttgga agaagcgcga aatgccaagg ttattgggaa atcattggaa gctcatttga
    12601 ctatctacgc tagcgaagaa gtgaaaacct tattgactgc tttagacagc gatattgctt
    12661 tgcttttgat cgtgtctcaa ttaaccattg ctgacttggc agatgcgcct gcggatgcag
    12721 tggcatttga aggtattgcc tttatggtag aacatgccat aggtgaagtt tgtgagcgtt
    12781 cacgccgcat cgacccaact actcgcatgc gttcttacaa tgcatttgtc tgtgatcaca
    12841 gcgctaaaat cattgaagaa aatttcccag aagctgtggc tgaagggttt gaagagagtg
    12901 gcaaataagt cttatcaaga cttgaagtga cactgagtaa gaagacaacc atcgggtctt
    12961 aggacctgat ggttttttag tagagctgat tacgttcatt agccagcttt aatgagagac
    13021 aaagtagaag aaatttagac tacttttttt atttctttta agaaaattgc tggcttcata
    13081 taaggactat taagatagag ttcacctttc gctaataaaa aaacttagct cttttagaag
    13141 ggctaagttt tgtctgaata gctggctact gtttatacag aagtttgaaa tgaaatttca
    13201 ataaggttat tcgtgtgaag tgtttttgat tgtccaggaa taacaatttt aggatcaatt
    13261 ttacgtttta aaaaaaattc gcgaatgata tcaagttcat cctctttgat ggcacggtat
    13321 ttatttgaaa taagtagttc gtaatgtttt ggtgcttggg taaaaatgac atctgtattt
    13381 cctgctgagt atacttcgac taaataggca tcggtgtttt ttagctgatt tctgatgagt
    13441 tctgggtgac tgctagtggt attgatgagt ctcataaatg tcctccttag tattcctgta
    13501 cctattatag cactaattta aagccttagt tagtagaatg atgctttttt tgccattcct
    13561 tgactcccca ttgatggctc tctcgtttta atttagcaat tgcctcgata ggagaaaacc
    13621 aacctaagtt attaaaatct tctaagggct tagaaacggc ttgaaatgca gttacttcat
    13681 aaagataggc aggatggtag aagtgggtat cacgatggcg agagtagaaa tattcatctg
    13741 cctgaccgta atatgaacca atagtagcag aaaaaccaag ttcttcaatc agttcacgct
    13801 ctagggcctg aagctgacct tcacctgctt caatttcacc accaggtaaa aaccaggaac
    13861 cattaggagc ttgaacaaga ataatttttg tttgttcgtg attgggaatg atagcataga
    13921 caccgtaacg tgtgacatag tctttatgtg catttttatg tccaaatgtt ggaatcatca
    13981 ttttatttac ctttcctttt tcttcattat actaaatttt tgctaattat tcttatcaat
    14041 ttgtttagtt taataaaaaa ttgatagaaa aagagagaat ctccttatag aaactctctt
    14101 agctaacgtt aatctagaga ctcttcgtta agaaaagaat ctccctcttt aacagcttta
    14161 atcgtgatgt tttcactgtt tgtcatcagt gcacgtaact gtttttcagt tgggtgttct
    14221 aaataatagt ctgtaatggc atcttcgata taatcttgga tagtacgacg gagcggccga
    14281 gcgcccattt taggatcata gcctaaatct actaattttt ctttgacctt ttgtgtcaca
    14341 tcaagatgaa tcccattata gcctaagcgc tcattaacat cttccagcat taaatcaacg
    14401 atatgcagca aatgttcttt agataaagct ttgaattcaa taataccatc gaaacgattc
    14461 ataaactctg ggctgaagaa gttgcttaat tcaccaagga cagaacttgt ccgtccttct
    14521 ctagcagcac caaatccgac agaagcttcg cttttacctg ttccggcatt agaggtcatg
    14581 ataataatgg tgtccttgaa gctgactgtt cgcccttggc cgtctgttaa gcgaccgtca
    14641 tcaagaactt gtaagaacat gtgcatgacg tcaggatggg ctttttccac ctcatctaag
    14701 agaataaggg aataaggatt gcgacgaact tgttcggtta gttgtccagc ttcttcatag
    14761 ccgacataac ctggaggagc cccgactaat ttggcgacag cgtgtttttc catgtattcg
    14821 gacatgtcaa agcgaatcat attgtttgtc gaaccaaaga gttcaatggc tagttgttta
    14881 gacaattctg ttttaccaac cccagtcggt ccaacgaata ggaaagaacc aatagggcga
    14941 tttggagttc ctaatcctac acggttacga cgaatagcct tagcgatttt atcaacagca
    15001 tcgtcttgcc cgatcacgtg tgctttcaga tcattggcta agtttacgag ttgagactgt
    15061 tccttttctt ttaagtcccc aactggaata ttagtttttt gctctacaat agcttcaatg
    15121 gttttttcag taatgatggg aatatcttgc tcatcgattt tttgagcctg catttctttg
    15181 tattttgtaa tttgatcgcg gaaataagct gcgcgttcat agtcttcgtc tcgagtagct
    15241 tgcgccttga gattctcagc ttcaataaga cgtttgtcaa tttctttagg atcaacaaag
    15301 ttgagggtta gattcatttt ggaaccagct tcgtccagaa ggtcaatagc cttatcagga
    15361 agaaaacggt cttgaatata gcggttagat aaatgagcag cagcttcaat agcggctggg
    15421 ctatatttga catgatgata gtcttcgtat ttcggttgga taccttttaa aatcgtgatg
    15481 gtttcctcaa cagaaggttc atcaacttta acgggttgca tacgtcgttc taaggcagcg
    15541 tctttttcaa taatacggta ttcatttaag gtggtagcgc cgaccaactg caattcaccg
    15601 cgggccaagg ctggttttaa aatattacca gcatccatat tgccgtctcc tgcagaacca
    15661 gcaccgacaa tctcatgaat ttcatcaata aagagaatca catccttgcg attgcgaatt
    15721 tcttccatta atttttgcat gcgctcttca aactgaccac ggatacctgt tccctgaacg
    15781 aggctaacca catcaagacg aatcacttgc ttgccttgga gtttttgagg aacagtacca
    15841 tcaataattt tttgagccaa accctctaca acagcagttt taccaactcc aggctcacca
    15901 attagcacag gattattttt agtacggcgg ttgaggatct cgataacgcg tgtaatctct
    15961 tcgtcacgac caataacagg atcaatatta ccatttcttg caatatctgt gacattaatc
    16021 ccaaactctt ctaacaagcc ctttgcttgc tgatttggtg tttgtggctg agcaggtcgt
    16081 tgtccgttgt agttaccacc atagcgtcct ccgccatttc cattttgccc tgcctgagta
    16141 ggtggggtat ttggaagatt accaaaagct ctaaaattat tcaaatcacc aaaaaagtca
    16201 tcaaagaaag gacttgtgga tctatcttgt gctctatatc ctggggttag gccatttaaa
    16261 atagaattgg caggatcgga tttcatgatt tgataacaat tttgacagag atcaacctgt
    16321 ctttgttttc cattaacact tgtataaaga tgaatagtag attcgtttaa attacaattt
    16381 tgacacagca taatatacct ccgagggttt atctaaaagt caaagtcatt tagtcaaaaa
    16441 tggtcaaact ttatattcat attatagcac cacggcttgg gaaatcaagt aaaaagttta
    16501 tcgctttagc gttagctttt agagagtaac atgacagagt aactttatta agtttccaat
    16561 gagcaaatgt ttaaaatcat tgaaaagagt aaaaaaagta aaatatcaat aaatatatta
    16621 ctttccttgt tagtttccct tgttttgtgt taaaataaga gggataaaaa acgaatagga
    16681 gaaacgaaat ggaatcacat ttggtgagaa tcatcaatcg tttggagttg atggtgacag
    16741 atggcggtaa tctcaagcga aattttgaac gcgatggtgt tgttgttgca gaagttgcct
    16801 tttcaaatga tcctgaaaat ggacctgttt tcacattgcg tgatgttgaa gcgcgtgagt
    16861 catattcctt tgatagtatt gacttgattg caatggaaat ctacgattta ttatattaag
    16921 cttgacatag taaagagact tgcctgaggc aggttttttt attgtcaaaa agtattgtat
    16981 taatattcat cagatggtat aattatcttt attgtaatga acctaggact tatgaggaga
    17041 tataaatgga tttgtcattt ttgcccaaat actgggccta ctttaactac ggtgtacttg
    17101 tcaccattat gatttcagtc agcgttgtct tttttggaac ccttattggt gtcttggtaa
    17161 ccctgattaa gcgtagtcat gtgaagccgt tgacctgggt cgttaatctt tacgtttgga
    17221 tctttcgggg aacacctatg gtggttcaaa tcatgattgc ctttgcttgg atgcatttta
    17281 acaatatgcc tactattggt tttggggttt tagacttgga cttttcaaga ctacttcctg
    17341 gaattattat catttcattg aatagcggtg cttatatttc agaaattgtt agagcaggta
    17401 ttgaggctgt accaaaaggg caattagaag cagcttattc actaggtatt cgtcctcaaa
    17461 atgccatgcg ttatgtgatt ttgcctcagg cctttaaaaa tattttacca gccttaggaa
    17521 atgaatttat taccattatt aaggatagtg ctcttttaca aaccattgga gtgatggaac
    17581 tttggaatgg tgcccaatcg gtggtaacgg ctacttattc tccaatttcc cctttactgg
    17641 tggctgcttt ttactactta atggtcacaa cagtgatggc acagttattg gcagtcttag
    17701 aacgtcacat ggcgcaagga ggtaatcatt gatgactgag gctattattt caattaaaga
    17761 cttgcacaag tattatgggc acaatgaagt gcttaaggga attgatttag acattatgcc
    17821 aggagaggtt gtggtgatta ttggcccgtc tggttctgga aaatcgacct tacttcgaac
    17881 tatgaatctt ttggaagtac caactaaggg acagattagg tttgagggga ttgatatcac
    17941 cgataagaag aatgatattt tcagcatgcg tgaaaaaatg gggatggttt ttcagcagtt
    18001 taacctcttt cccaatatga ctattttaga aaatatcact ttatcgccaa tcaaaactaa
    18061 gggaatggct aaagcagagg ctgacaaaac agccttgagc ttgttggaca aagttggatt
    18121 atcagaaaaa gccaaggctt atcctgctag tctttctggt gggcaacagc agcggattgc
    18181 gattgcgcgt ggactggcta tggatccaga tgttttactc tttgatgaac caacttcagc
    18241 tctagaccca gaaatggtgg gtgaggtctt ggctgtcatg caagatttgg ctaaatctgg
    18301 gatgactatg gttattgtga ctcatgaaat gggctttgct aaagaagtcg cagaccgtgt
    18361 gatttttatg gatggcggcg ttattgtgga agaaggaagt cctaaccaac tttttgatct
    18421 gactaaagaa gaacgtacaa aagatttttt gagtagagta ttataaatct gttctatgaa
    18481 ttataaaagg aagtcctaaa tgatttagga cttcctttta taatttgcta aggcatttta
    18541 taggagatta cttttctttt tgttaaaata aaaagaaata gttgcattat ttgcatagaa
    18601 gaaagggatc tgttatggtt tcagtgatgt ggtttcgtag agatttaagg attgatgatc
    18661 aaaaagcttt agctcatgct attgctagtc aatcaccaac cttatgtgtg tttcaattta
    18721 acaaggagca attaaatctg ctacatagtc ggaatcaatc tagttttatt actagcgttt
    18781 tggcttttag aaagttatta aaatgtgaag gtattgactt atatctaatg tatggagact
    18841 taatgacctg ttttgagcaa ttattgacac aattaaaaga ctggacagat gtgtatttta
    18901 actatgatga atctggatat ggtcgtttac gtgatcaaaa agcagcacaa tttttcaaaa
    18961 aaaatgggat tgctgttcat acctaccaag atcactattt acatggtagt caagagatca
    19021 ttaaccaatc aggtcagcct tataaagttt ttacgcccta ctataggatt tggcaaaatt
    19081 atccgaaaga gactcctatt aaagtagaac tatcgcaagg caggtggtta aatcttgaga
    19141 caccagatga tgttttaagg actgttgaga gttttaaaga tgaaaaatat caggatgttg
    19201 caacttctga tgaagcgtca aaacaactaa atcgatttat tcaagaccaa ttagcagctt
    19261 atcacgctaa tcgagatttt ccagcgcagc tagggacgag tcggttgtct ccttttttaa
    19321 gaataggagc tattggcatt cgcacggtat atcacgctgt gcgtcaagca ccaaatagtc
    19381 tagggcaagc tactttttta aaagaattag cttggagaga cttttacaat atggtctatg
    19441 tggcttatcc tgatcagaaa actcagccta tccaaaaagc cttttctcaa atcgaatggg
    19501 ttaataatcc tgactggttt cagttgtgga aagaaggtaa aacgggttac cctattgttg
    19561 atgctgccat gcttcagtta caaaagacag gatggatgca taatcgttta cgaatgatag
    19621 tagcttcttt tttaactaaa gatcttttat gtgattggcg tttaggagag cagtattttc
    19681 aacaacaact aattgattat gatgctgcca gtaatatcgg aggatggcag tgggctgctt
    19741 ccactggaac agatgctgtt ccttatttta gaatatttaa tcctgttact caaggtaagc
    19801 gctttgatcc caaaggcgag tttattaaag cgtatttgcc tcaactagaa tacgttccag
    19861 agaagtatct ccacgaaccg tggaagatgc caaaaaacct tcaagagagt gtgtcctgta
    19921 ttattggcac agactatcct caaccaattg tcgatcatgc taaacaacgt gaacaagcta
    19981 ttgcaaagta tgagtgggca aaagaaaaag taaaaataga atgactgttc tcattataag
    20041 agtttaaaca aaaagttatc atgaattaag attatttaat ttaaaaaata agttgacttt
    20101 atttagatta tttgatacta ttcagttgtc tcccttagag aaagcgattt cttgttttgg
    20161 agctgatttt taccatttgg tcttagaata ggatgagtaa tatgacttac aacgaggtat
    20221 atcaagaatg gttgcacaat aatgatctta gtgatgatat taaagcagat ttagcagcca
    20281 taaaagacaa tgaggctgag attcaagatc gtttttacaa aacacttgaa tttggaacag
    20341 cagggctaag aggaaaactt ggagcaggca ccaatcgcat gaatacctat atggttggta
    20401 aggcagcaca agctttagct aatactatta ttgatcatgg acctgaagca gttaaaaagg
    20461 gcattgcggt tagttatgat gttcgctatc aatctagaac atttgcagaa ttaacatgct
    20521 ctattatggc agctaacggt attaaggcgt acctttataa agggattcgg ccaacaccaa
    20581 tgtgttcgta cgctattcgt gctttgggat gtatctctgg tgttatgatt acggctagtc
    20641 acaatcccca agcttacaat ggttacaaag cttattggca agaaggttct caaattttgg
    20701 atgacattgc ggatcaaatt gcacaacaca tggctgcact aactcagtat caggaaatca
    20761 aacaaatgcc ttttgaaaag gctctggaca gtggacttgt tacttatatt gatgagagta
    20821 ttgaagaagc atataaaaaa gaagtgcttg gtttaacgat taatgatact gacattgata
    20881 agtcagtccg agtagtctat acccctttaa atggtgttgg gaatctacca gtgcgtgagg
    20941 ttttaagacg ccgcggtttt gaaaatgttt atgtggtacc tgagcaggaa atgcccgatc
    21001 ctgattttac aacagttggc tatcctaatc ccgaagtccc taaaactttt gcatattcag
    21061 aaaaattagg taaggcagtt gatgctgata ttttgattgc aactgatcca gattgtgacc
    21121 gtgtggcttt agaagttaaa aatgcagtcg gtgactatgt ttttctcaat ggtaataaaa
    21181 tcggagcgct tttatcttac tatatctttt cacaacgatt tgacttaggc aatttaccgg
    21241 ctaatcctgt tttagtgaaa tccattgtaa caggagactt gtcacgggct attgctagcc
    21301 attatggtat tgaaaccgtt gaaacattga ctggttttaa gaatatttgt ggcaaggcaa
    21361 acgaatatga tgtgacgaaa caaaaaaact atctgtttgg ttatgaagaa agtattggtt
    21421 tttgctatgg cacttttgtt cgtgacaaag acgctgttag cgcctctatg atgattgtag
    21481 aaatggcagc ttactacaag aaaaaggggc agaatttact agatgttttg cagactattt
    21541 atgcgacatt tgggtattat aatgaacgtc aaattgcctt ggagcttgag gggatagaag
    21601 gacaaaaacg cattgcgagg ataatggaag atttcagaca gacaccaata gctagtgttg
    21661 cagagatggc gttagacaag acaattgatt ttattgatgg ctatcaagat tttccaaagc
    21721 aaaactgtct caaattttat ttggatgatg gttcttggta tgcacttaga ccatcaggaa
    21781 cagagcctaa aataaaattt tatttatata ctattggcca aacacaagaa aatagtgtaa
    21841 caaaattaga tgctattgaa gcagcgtgtc gcacaaaaat aaatcaggtt aattaaacat
    21901 caaaaatgga taacactttt acactatttt tccatataaa caactacaaa aggaggtgag
    21961 acttttaggc accttctttt tcttgtaggt gccactaacc aatttaatcg actcaaacca
    22021 atactaaaaa ataagtaaga gtataaagaa caggcatcta tttttttgtt ataatagaaa
    22081 aatgaaatta aagggagatg tcaatgacag aactaattga tggtaaagcc ttagctcaaa
    22141 agatgcaaca agagttagca gctaaagtca acaatctaaa acaaaacaaa ggaattgtac
    22201 caggcttagt cgttattctt gtaggtgatg atcctgctag tcaggtgtat gtccgtaata
    22261 aagagcgtgc agctcttact gtaggtttta aaagtgagac cgttagatta tcagaattca
    22321 tttgtcaaga agagcttatt gcagtaatcg aacgttacaa tgcagataac actattcatg
    22381 gtattttagt gcagttaccc ctgccaaatc atattaatga taaaaaaatt attctcgcca
    22441 ttgatcccaa aaaagatgtg gatggttttc acccgatgaa tacaggtcac ctttggtcag
    22501 gacgtccctt gatggttcct tgtactccat cagggattat ggaattgctt cgagaatata
    22561 atgttaacct tgaaggtaaa catgccgtca ttattggcag atcgaatatc gttggaaaac
    22621 caatggcaca gctcttactg gacaaaaatg caacagtcac gttgacacat tcaagaacac
    22681 gtcaattaga agaagtatgt cgctgtgcag atgtgttgat tgtggcaatc ggacaaggtc
    22741 atttcataac aaaacaatat ataaaagatg gtgcgatagt gattgatgtg ggaatgaacc
    22801 gtgatgataa tggcaagcta attggagatg tggcctttga tgaggtggca gaagttgcag
    22861 cgaaaatcac ccctgtacca ggaggtgtcg gtcctatgac gattgctatg ttgctagagc
    22921 aaacttatca atctgccctc cgtagtactc ataaatagtt ataattagac aattcaacat
    22981 aagagaatat aagaagtcag caatggcttc cttttttgtt tttctgctca ctatttatcc
    23041 agaaaaatgg tataattgca ttagtatgca aagggactat gtcaggtcca actaagtgaa
    23101 aggtggcttg atggcagatt atttaaccgt cactcatttg acgaaatatt taaaattaaa
    23161 atttgaccgt gacccttatt tggaacgggt ttatctgact ggtcaagtgt ccaattttcg
    23221 aaaacgacca actcatcaat atttttcctt aaaagatgaa agtgctgtga ttcaagccac
    23281 catgtgggca ggagtctata aaaaactagg attcgaccta gaagaaggca tgaaaattaa
    23341 tgtaattggg cgagtccaac tttatgaacc tagtggctct tactctatcg tgattgaaaa
    23401 ggcagagcca gatggtatag gtgccttggc tttgcagttt gaacaattaa agaaaaaatt
    23461 aacggcagaa ggttattttg agcaaaaaca caagcagccc ttgccacagt ttgtatcaaa
    23521 aattggggtc attacaagtc ctagtggtgc tgtgattcga gatattatca caaccgtttc
    23581 acggcgtttt ccaggggttg agattttatt attcccaacc aaagtacaag gtgatggagc
    23641 cgcccaagaa gtagtggcta atattcgaag agccaatcaa agagaggatt tggacttgct
    23701 cattgtcggc cgtggaggtg gctcgataga agacctttgg gccttcaacg aggaaatagt
    23761 ggttcaggct atctttgaat cgcaacttcc agtgatttcg agtgtgggtc atgaaacaga
    23821 cacgacttta gcggattttg tggcagatcg cagagcagcc acaccaacag ctgcagcaga
    23881 gttagcaacg cctattacaa aaatagatct tatgtcttgg atagtagagc ggcaaaatcg
    23941 ttcctatcag gcctgcttga ggcggattaa gcaacggcaa gagtgggtgg ataaactctc
    24001 gcaatctgtt atttttaggc aaccagaacg attatatgat gcctacctgc aaaaaattga
    24061 tcgccttagc atgaccctga tgaatacgat gaaagatcgt ctgagttccg ccaaagaaaa
    24121 caaggttcag ttggaccatt ccttggccaa tagtcaatta cagacaaaaa tcgagcgata
    24181 ccaagaccgt gttgctaccg ctaagcgttt actgatggct aatatggcta gtcaatatga
    24241 tagtcagctg gctcgctttg aaaaagcaca ggatgctttg ctatcactgg atgccagccg
    24301 aattatcgcc cgtggttatg caatgattga aaaaaatcaa gcactggtag cctctgtaag
    24361 tcagataaca aagggtgatc agttaaccat taagatgcgt gatggacaat tagatgtaga
    24421 ggtaaaagat gtcaaaaacg aaaacatttg aagaaaattt acaagattta gagactattg
    24481 tgaacaaact tgaaaatggg gatgtccctt tggaagaagc tatttcagaa tttcaaaaag
    24541 gaatgcttct ctcaaaagaa cttcaaaaga ccttacaagc ggcagaaaaa acactcgtca
    24601 aagtgatgca agctgatggc acagaagtag atatggatga ttaatggaca aattagctag
    24661 aattgacgaa gccattcgtc gctactataa gacgactagt aacggtgtat ctgaagagtt
    24721 gattgatgct atcttgtatt ctgttgacag tggtggcaag cgcattcgcc cacttatctt
    24781 attagagatg attgagggat ttggggtatc gttacagaat gctcattttg atttggctgc
    24841 agcccttgaa atgattcata caggaagtct gattcacgat gatttgccag ccatggataa
    24901 tgatgattac cgacgtggta gactgaccaa tcacaaacaa tttggagagg ctactgctat
    24961 tttggcggga gatagcttat ttttagaccc ctttgggtta atagctcaag ctgaattaaa
    25021 tagcgaggtt aaagtagcct taatccaaga actttcccta gcttcaggaa cttttggcat
    25081 ggttggtggt cagatgctag atatgaaagg ggaaaatcaa gctttgagtc tccctcagtt
    25141 gtcactgatt cacctcaata aaaccggaaa attattaact tttcctttta aagcagcagc
    25201 tcttgtaaca gaacaggcta ttactgttcg tcaacaacta gagcaggcgg gaatgctcat
    25261 cgggcacgcc tttcagatta gggatgatat tttagacgtg acagctagct ttgaagatct
    25321 tggaaaaacg cctaaaaagg atttatttgc agaaaaagct acttacccaa gtttactggg
    25381 gttagaagcc tcctaccaac tgttgacaga gagtttagat caggctttga cgatttttca
    25441 gacactcgaa agcgatgtag gctttaagcc tcaaataatt acaaaactga tagaagggtt
    25501 acgacttaat gcctaaagaa agagtagatg tgttagccta taagcaagga ttatttgaga
    25561 ccagagagca agctaagcgt ggtgtcatgg caggcttagt ggtctctgtg attaatggcc
    25621 aacgctatga caagccaggt gacaaaattg acgatgggac tgagttaaaa cttaaaggtg
    25681 aaaaactcaa atacgtcagt cgtggtggat taaaactgga aaaggggctg cacgtttttg
    25741 gtgtatcggt tgctaatcaa attgggattg atattggcgc ttcaacaggt ggttttaccg
    25801 atgttatgtt acaagatggg gccaaactag tctatgccgt cgacgttggg actaaccagt
    25861 tggtatggaa actcagacaa gatccacgag taagaagtat ggaacagtat aactttcgtt
    25921 atgctcagcc agaagacttt aatgagggac agcctgtatt tgccagtatt gatgtgtcct
    25981 ttatttctct cagcttgatt ttgccagccc tgcataacgt tttgtcagat cagggacagg
    26041 ttattgctct cattaaaccg caatttgaag ctgggcgcga gcagattggt aaaaaaggca
    26101 tcgtcaagga caaacagatt catgaaaaag tgattcaaaa ggtcatggat tttgcctcag
    26161 gttacggatt tacagttaag ggacttgatt tttcccctat tcagggtggt catggcaata
    26221 tcgaattttt agctcatctt gctaagtcac agacacctga aacgttagcc ccgcatttga
    26281 ttcagaaagt tgttgccaag gcacataagg agtttgagaa acatgaaaaa gagtgaacga
    26341 cttgaattaa tcaaaaaaat ggttttgacg catccaattg agacgcaaca tgacctctta
    26401 agattattgg cagagcatgg gttagaatta acccaggcta ctatttcaag agacatgaat
    26461 gaaattggta tagtaaagat tccttctggc agtggacgtt acatctatgg tctttctcaa
    26521 gatagtggaa aaaagatcgt tcaaggacct agatcgataa agagcactat tttagctgta
    26581 tctgacaaaa caaaaggttt agaacaacac ctctatttaa aagtcgtacc tggcaatagt
    26641 aaattaatca aacgttattt attagcagat ttttcaaaag ctatttttag tcttattgct
    26701 gatgatgata gtttattgtt aattgcaaag tctccttcag aagcagatat gatacgccaa
    26761 gaaattttgc tttggatgca gggtataacc tagaaaaaaa taggggagaa agtgatgtta
    26821 ttagaaattt ctattaaaaa ttttgctatt attgatgaaa tttccctaaa ttttgaaaat
    26881 ggtatgacgg ttttgacggg tgaaactgga gcaggaaagt ctattatcat tgatgctatg
    26941 aatatgatgc ttggtgcgcg tgctagtaca gaagtgattc gtcgtggagc taataaagca
    27001 gaaattgagg ggttcttttc ggtagatgct accccagaac tggttgcgtg tctggaatca
    27061 tcaggtattg ctatggaaga agaactgatt attcgccgag atatctttgc caatggcaga
    27121 agcgtgagtc gcattaatgg tcagatggtt aacctagcca ccttaaaaca ggtcggacag
    27181 tttttggtag atattcatgg gcaacatgac caagaagaat taatgcgacc acagctccac
    27241 cagcaaattt tggacgcttt tggtgataag gcttttgagc aattgaaaga gaactatcag
    27301 cttatttttg atcgttataa aagcttgcgt cgccaggtta ttgacaaaca aaaaaatgaa
    27361 aaggaacaca aagatcgtat tgatatgttg gcctttcaga tagcagaaat tgaagctgct
    27421 gccttgagtc gaggtgagga cgaccggtta aatcaagaac gtgatcgctt aatgaaccac
    27481 aaacaaattg ctgataccct gaccaatgcc tacgtcatgc tagataatga cgatttttca
    27541 agtctatcca atattcgctc tagcatgaat gacttactat caattgagca gtttgattca
    27601 gagtacaaag ggatgtcgac ttcgatttct gaagcctatt atattcttga agaagtgagc
    27661 aagcaattat cagataccat tgaccaactg gattttgatg gtgggcgatt acaggaaatt
    27721 gaatttcgct tggatacact caatagctta acccgtaaat acggtggtaa tgtgaatgat
    27781 gtgcttgact actacgataa tattatcaaa gaataccagc tattaacagg agacgacttg
    27841 tcttcagggg atctagaatc agaattgaaa gccttagaaa aacaattggt tgctgcagcc
    27901 actaacttga gtgaacgccg ccatcaattg gcggagcaat tagaagctga gattaaagct
    27961 gaacttaagg aactttatat ggaaaaagca gatttcaaag ttcactttac cacatcaaaa
    28021 ttcaatcgtg atggtaatga aagcttggaa ttttacatct ctactaatcc aggcgaagga
    28081 tttaagcccc ttgtcaaggt ggcttctgga ggagagttat cacgccttat gttagccatc
    28141 aaggctgcta tttctagaaa agaagataag acgagtattg tttttgatga agtagataca
    28201 ggtgtttctg gtcgcgttgc gcaagccatt gcccaaaaaa tttataaaat tgggcgacat
    28261 gggcaagttc tcgctatttc acacttacct caagttattg ctattgctga ttatcagtat
    28321 tttatttcta aagaaagtaa agaagagtcc accgtttcta aggtaaggtt attaactcct
    28381 gaagaacgtg tggaagaaat tgctagcatg attgcaggaa cagatatgac acaagctgct
    28441 cttacgcagg ctcgtgaact acttgccaaa cattaagatt atgtttggta tttgatattt
    28501 tcataattag atgacattga ttttttaggt gctaaaataa tcattgtgct agaccatttt
    28561 tcctctgtta atctggcttg gtttgccttg acaaacctct gagaaatagt agaatagata
    28621 agagaatttt aagctgaggg gatagaaatg actagtaaaa aagcgtgttt atcaagcatc
    28681 attgtgttag caagtttaac gtgtggaaat gatactgtta gtgccaatca tctctcagca
    28741 actggagata agtttgatga ttgctcaaca cttgttgaaa aagatgtggc ccctaaagat
    28801 gaacttgaga tgttagcatg gtcctcgtct caaacaactg atgatgctga cagagactat
    28861 gaagattttc tcgatgatga ttcttttaat gatgattctt ttatttctca aaatgaaact
    28921 gataagatgt ttgagaattt aactgatgat aggttattaa atgaattaaa tgaattagat
    28981 gaattagatg aattagatga attagatgaa ttagatgaag aagatacaat tgagccagag
    29041 caaaatgtaa taatgcctag tgacgatgag ctatttgatt taactgatgc tgttgagaca
    29101 cgccttactg tttctagtgc tccccattta gaggctgaat tgccgaaacc acatttgagg
    29161 agcctatcag atacagcact gcggtctggt gaaattagag gacatttaga taacaaactg
    29221 gacactttgt ctgtaacagc tacaaagtta gcattaacga tggctcaaaa atttgatttg
    29281 acaacgcatg tctattctat aggtgaaagc tttagtgaag tattagctgc tcattatgaa
    29341 gacagaaaag cagaatcagc tttttctaag aaaaagagat ttcaccttcc tattgctact
    29401 ccagatgttg ttatagagga gttaaggcgc ctagtctctt ctattggaag ttcaaaagaa
    29461 gatgtttcag ttccttataa tcggaagcta ggtatggcag ttgcaaaaag aaaaatagcc
    29521 ctgccacaaa cgggagagga gttctcttat tatccagctt tacttggttt aatgatatta
    29581 ggattaacgc cgattatgat accaaagaag ataaataatt aggtaataag ttattgtagt
    29641 tgtaaaagac ggggcaaatg ttcaagcgtg aaaaggttga cttttgcctc gttttgtatc
    29701 tcgttattgc taaggcattt tcttcgagca gctagtgctc gccataccta tctaccgagt
    29761 gattattcaa tagcactacc acgccaaacg catga
//
LOCUS       DAUNLR010000018        29471 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUNLR010000018 DAUNLR010000000
VERSION     DAUNLR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29471
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.018"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..275)
                     /gene="spej"
                     /locus_tag="VLL59_000819"
     CDS             complement(<1..275)
                     /gene="spej"
                     /locus_tag="VLL59_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeJ"
                     /protein_id="HER6508957.1"
                     /translation="MKRIIKTIILVIIIFHGYGSVKSDSENIKDVKLQLNYAYEIIPV
                     DYTNCNIDYLTTHDFYIDISSYKKKNFSVDSEVESYITTKFTKNQKV"
     gene            complement(523..1137)
                     /locus_tag="VLL59_000820"
     CDS             complement(523..1137)
                     /locus_tag="VLL59_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508958.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDEQNKFILDGLQEKVKEVSVS
                     DFSVGESEIKVWLPQAWSVKISREHSPKSSISNSGEQKPLSNSSENKEGQFSKRLPYG
                     TQHTIKLSSQLTKGERVTLTFRDEDFWGAGYCFYRDSLSIKEDKQYEEEIKKIEDDLE
                     RQDLENDALEMFKKQTEREANKPWHQRLSENIQDQWWNFKGLFQ"
     gene            1498..1734
                     /locus_tag="VLL59_000821"
     CDS             1498..1734
                     /locus_tag="VLL59_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HER6508959.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVNG"
     gene            1727..2425
                     /locus_tag="VLL59_000822"
     CDS             1727..2425
                     /locus_tag="VLL59_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HER6508960.1"
                     /translation="MAKVVLVTGCASGIGYAQTRYFLRQGYHVYGVDKSDKSDLSGNF
                     HFIKLDLSSELSPLFEVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRHMVEKRSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTKPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            2501..3460
                     /locus_tag="VLL59_000823"
     CDS             2501..3460
                     /locus_tag="VLL59_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HER6508961.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTAKDLA
                     KAYKMPLATSKYETVLGNEEIDTVYIGLPNHLHFAYAKKALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANMDKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVELVIYGQKPQVINHNKH
                     DHRMYEEFVAFKDMIDQRDFEKVNQALEHSRAVMAVLERAVHS"
     gene            3793..5130
                     /locus_tag="VLL59_000824"
     CDS             3793..5130
                     /locus_tag="VLL59_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HER6508962.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASAFICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            5303..6685
                     /gene="glmU"
                     /locus_tag="VLL59_000825"
     CDS             5303..6685
                     /gene="glmU"
                     /locus_tag="VLL59_000825"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HER6508963.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKAVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGQGSIITNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEIGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            6716..7270
                     /locus_tag="VLL59_000826"
     CDS             6716..7270
                     /locus_tag="VLL59_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HER6508964.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTFIALQYYALHFGGEQ"
     gene            7270..7521
                     /locus_tag="VLL59_000827"
     CDS             7270..7521
                     /locus_tag="VLL59_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508965.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVDFDTKVMTLPEKDDKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            7540..8235
                     /locus_tag="VLL59_000828"
     CDS             7540..8235
                     /locus_tag="VLL59_000828"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HER6508966.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQILMTFLENLPV"
     gene            8386..8727
                     /locus_tag="VLL59_000829"
     CDS             8386..8727
                     /locus_tag="VLL59_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508967.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNKGYHQHLTD
                     PKSHLQYSKDNAQLQLRNILNGYQSDLGKHYSSYYYYNLRTVMGLSSEQKIEEHYEKL
                     KDELYRIYNHY"
     gene            complement(8826..9473)
                     /locus_tag="VLL59_000830"
     CDS             complement(8826..9473)
                     /locus_tag="VLL59_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HER6508968.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILNFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            9619..10551
                     /locus_tag="VLL59_000831"
     CDS             9619..10551
                     /locus_tag="VLL59_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HER6508969.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            10615..11340
                     /locus_tag="VLL59_000832"
     CDS             10615..11340
                     /locus_tag="VLL59_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HER6508970.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGYTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            11341..12195
                     /locus_tag="VLL59_000833"
     CDS             11341..12195
                     /locus_tag="VLL59_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HER6508971.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLGVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(12343..13149)
                     /locus_tag="VLL59_000834"
     CDS             complement(12343..13149)
                     /locus_tag="VLL59_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HER6508972.1"
                     /translation="MKKLLSLSLVAISLLSLSACEYVDRAIKGNKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            13366..15771
                     /locus_tag="VLL59_000835"
     CDS             13366..15771
                     /locus_tag="VLL59_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HER6508973.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFSWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMPKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDRPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(15841..16194)
                     /locus_tag="VLL59_000836"
     CDS             complement(15841..16194)
                     /locus_tag="VLL59_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HER6508974.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            16438..16863
                     /gene="rplK"
                     /locus_tag="VLL59_000837"
     CDS             16438..16863
                     /gene="rplK"
                     /locus_tag="VLL59_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HER6508975.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            16969..17658
                     /gene="rplA"
                     /locus_tag="VLL59_000838"
     CDS             16969..17658
                     /gene="rplA"
                     /locus_tag="VLL59_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HER6508976.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            17980..18708
                     /locus_tag="VLL59_000839"
     CDS             17980..18708
                     /locus_tag="VLL59_000839"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HER6508977.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            18737..19294
                     /gene="frr"
                     /locus_tag="VLL59_000840"
     CDS             18737..19294
                     /gene="frr"
                     /locus_tag="VLL59_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HER6508978.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            19403..20260
                     /locus_tag="VLL59_000841"
     CDS             19403..20260
                     /locus_tag="VLL59_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HER6508979.1"
                     /translation="MNDLLATVITGLIKEENAIDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVCRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            20333..20842
                     /gene="msrA"
                     /locus_tag="VLL59_000842"
     CDS             20333..20842
                     /gene="msrA"
                     /locus_tag="VLL59_000842"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HER6508980.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNSKRYAQSSAIR
                     HQFLEENWS"
     gene            20839..21054
                     /locus_tag="VLL59_000843"
     CDS             20839..21054
                     /locus_tag="VLL59_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HER6508981.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            21210..22373
                     /locus_tag="VLL59_000844"
     CDS             21210..22373
                     /locus_tag="VLL59_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HER6508982.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQPTVPMAPSATPSDVPTTPLASAKPDSSVT
                     ASSELTSSTNDVSTESSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEGPTSANRP
                     VPNESASEEVSSAAPAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMNAG
                     LQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYAID
                     HMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            22687..24459
                     /locus_tag="VLL59_000845"
     CDS             22687..24459
                     /locus_tag="VLL59_000845"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HER6508983.1"
                     /translation="MYYTSGNYEAFATPRKPEKVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMTGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSVVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKENETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     GLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            24618..25670
                     /locus_tag="VLL59_000846"
     CDS             24618..25670
                     /locus_tag="VLL59_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HER6508984.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            25716..26291
                     /locus_tag="VLL59_000847"
     CDS             25716..26291
                     /locus_tag="VLL59_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HER6508985.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            26450..26947
                     /gene="ybeY"
                     /locus_tag="VLL59_000848"
     CDS             26450..26947
                     /gene="ybeY"
                     /locus_tag="VLL59_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HER6508986.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            26928..27335
                     /locus_tag="VLL59_000849"
     CDS             26928..27335
                     /locus_tag="VLL59_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HER6508987.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            27455..28351
                     /gene="era"
                     /locus_tag="VLL59_000850"
     CDS             27455..28351
                     /gene="era"
                     /locus_tag="VLL59_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HER6508988.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFHYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            28371..28847
                     /locus_tag="VLL59_000851"
     CDS             28371..28847
                     /locus_tag="VLL59_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HER6508989.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
BASE COUNT         8953 a         5240 c         6371 g         8907 t
ORIGIN      
        1 tttacttttt gatttttcgt aaactttgtt gtaatatagc tctcgacctc agaatcaact
       61 gaaaaatttt tctttttata actggaaata tcaatataaa aatcatgagt agtcaagtaa
      121 tcaatattac aattcgtata atctactggt atgatttcgt atgcgtaatt taattgtagc
      181 ttaacgtctt taatattttc actatctgat tttacacttc cgtacccatg aaagattatt
      241 ataactaaaa ttattgtttt tattattctt ttcatacctc tcctcgttca cctcgtaccc
      301 cacaaactac tttatcctaa aaaaccataa aatcaacatt gaggactttt ttggttccca
      361 taaattgtta actatgtcat tttagagcaa tcatatagag actaagatat aattttacca
      421 aagttttgaa agctattgaa gagtatcttg attttgtcta ggttctaagc acctgtaagg
      481 gtgctttttg tgctttagcc aacctcatag tctagtaaac cctcactgaa acagtccctt
      541 aaagttccac cactgatctt ggatgttttc gcttaaccgc tgatgccaag gtttattagc
      601 ctctctttcg gtttgttttt taaacatctc tagtgcatca ttttcaagat cttgtctctc
      661 taggtcatcc tcaattttct taatttcttc ttcgtattgt ttgtcttctt ttatggatag
      721 tgaatctcta tagaagcagt aacctgctcc ccaaaaatct tcatctctga atgtcaaagt
      781 gactctctca ccttttgtaa gttgggatga taatttaata gtatgttggg taccataagg
      841 taatctttta gaaaattgac cttctttatt ctctgagcta ttgcttaaag gtttttgttc
      901 tccagaatta gaaatgcttg attttggtga atgttctcta gaaattttga ccgaccaagc
      961 ttgaggaagc cagactttga tttcagattc tccaacagaa aaatctgata cactaacttc
     1021 ttttactttt tcctgtaatc catcaagtat aaacttattc tgttcatcct ccgctctgac
     1081 gctactagtt accccgatgg caaagagtgc cagtagcaag gttaatgtct ttttcatttt
     1141 ttcctctcct tttgctcatt ttttaagata aggattatta taccaattct tgcgctaaaa
     1201 agatagggag ttcatgcctt gtggttggga aatggcgcga ctattcttgg taggggcaga
     1261 caggtttttt cctagccagt tgctagccgt tgccatttta cctttgcaag ccgtttgggc
     1321 atcaggtcgt gttttgaggt tgccaatact tttagttgct ttttgacaaa aatgcgttat
     1381 gatagactaa ataaaagaag atagcatttt cggtgaatga tgcgtgagtc cacaaattta
     1441 tttttaggag tttatagact gcctaaagta tctatttcgt caataaagga gaacaatatg
     1501 acatttgaag agattttacc aggtttaaaa gccaagaaaa aatatgtacg tacaggttgg
     1561 ggtggcgctg aaaattatgt gcagttgttt gatacccttg aagtggatgg gaaagtacta
     1621 caggcgacac cttattttct gattcatgtt actggtgcag gtgaaggttt ttccatgtgg
     1681 gcaccgacac catgtgatgt gttagcagag gattggatcg aggtcaatgg ctaaagttgt
     1741 tttagtgacg ggctgtgcta gtgggattgg ttatgcacag acccgctatt ttttgagaca
     1801 agggtatcac gtatatggtg tggataagtc ggataagtcg gacttaagcg gtaattttca
     1861 ctttatcaaa ttggatttat cctctgagtt atccccacta tttgaagtgg tccccagtgt
     1921 tgatattttg tgtaatactg cagggatttt agatgcctac aagccacttt tagacgtcag
     1981 tgatgaagaa gtggaacacc tatttgatat taattttttt gcgacggtga agttaacacg
     2041 tcattatctt agacatatgg tggaaaagcg gtcaggtgtt atcatcaata tgtgctcaat
     2101 agcaagtttt atagcgggtg gcggtggtgt tgcctatacg agttctaagc atgcccttgc
     2161 gggcttcacg cgccaattgg ctttggatta cgccaaagat cagattcaca tttttggtat
     2221 agcaccaggt gctgtcaaaa ccgctatgac ggctagcgac tttgagcctg gtggcttggc
     2281 agactgggta gctcgtgaga cgccaattgg tcgttggact aaaccagatg aagttgctga
     2341 attaacggga tttcttgctt caggaaaagc gagatcaatg caaggtgaaa ttgtcaaaat
     2401 tgacggtggc tggactttga aatgatcaca tgccttagct tgagctggcg cagtaggccc
     2461 tagaggtgtg atgagtcaaa cagtcaaagg agatgaacaa atgaaattag cggttttggg
     2521 gacaggtatg attgttaagg aagttttgcc tgtcttgcag aaaattgatg gtattgattt
     2581 agttgctatc ttatcaacag ttagaagttt aacgacagct aaagacctcg ctaaggcata
     2641 taagatgcct ctagctacga gtaaatatga gactgtctta ggcaatgagg agattgacac
     2701 agtttatatt ggactgccaa atcacctgca tttcgcctat gctaagaagg ctcttctagc
     2761 tggtaaacat gtcatttgtg aaaagccctt taccatgaca gcaggagaat tagatgaact
     2821 ggtggtaatc gctaaaaaac gaaaactcat tttgttagaa gcgattacga atcagtattt
     2881 aagcaacatg acctttatca aagagcatct tgaccaactt ggcgatatca aaattgtaga
     2941 atgcaattat tcacaatatt cttcacgcta cgatgccttc aaacgaggtg atatcgcgcc
     3001 agcttttaat cctaaaatgg gtggtggagc tttacgtgat ttaaacatct acaacattca
     3061 ttttgtggta gggttatttg gtcgccctaa aacggttcaa tatttagcca atatggacaa
     3121 aggcattgac acatcaggca tgcttgtcat ggactatgag cagtttaaag tggtgtgtat
     3181 tggggccaaa gactgcactg cggaaatcaa gtccactatt caaggtaata aagggtcact
     3241 ggcagtgctt ggagcaacaa atacccttcc tcaggttgag ctcgttattt atggtcaaaa
     3301 accacaagtg attaaccaca acaagcatga ccaccggatg tatgaggagt ttgtcgcttt
     3361 taaagacatg attgaccaaa gagactttga gaaagtgaat caggctttgg aacatagccg
     3421 agctgtcatg gctgtgttgg agcgagctgt tcattcgtga ttgtaaccta gtaaccattg
     3481 ccttttgtgc agttgctatg gtaatggttg aaagacgtgt tttcacgagg gttaaccccc
     3541 tcgttctttt ttggcaaaaa taacttgttc aggatttggg ccttctttgt gagatgagag
     3601 atgcctgacg aattgatttg attaaaataa tgataaagcc aaacgattta agaaatgtcc
     3661 gttcggaaat tctgccccaa agggtctcta gaagcagtaa aatcgaattt gtaagcgttg
     3721 acactgttgc ataactctgt tacactaaga gaatgtcatg acaaaaatta cagtgtagga
     3781 gtttaattgt ttatggaaga ggattataac aaaagagaac ctgagaagtt tacgcaattt
     3841 ctgcgccgtc aaaaggtcgt cttttttgtc gcattttttg gttatgtgtg tgcttacttg
     3901 gtacgcaaca atttcaaact aatgtcaaac actattatgg tgcaaaatgg ttgggacaag
     3961 gctcaaattg cgaccttgtt atcgtgtttg accgtttctt atggcttagc aaaattctat
     4021 atgggggcct taggggatcg tgttagcttg aggaagctct tttcaatcag cttgggtgca
     4081 agcgctttta tttgtatttt aatcggtttt ttcaatagtt caatggtggt gttagggata
     4141 ctgctagtct tgtgtggtgt cgtacaaggt gccttggcac ctgcctcaca agccatgatt
     4201 gccaattatt ttccaaataa aacacgcggc ggagccatcg ctggatggaa catttctcaa
     4261 aacatgggat cagccctctt gccattaacc atcgccttgc tcaccagtat gggcctggtg
     4321 gtaccagcta atggtaatat tttacttgcc tttttaatcc ctggcgtttt agtgttcttg
     4381 tttgctttgt gttgctggaa gcttggcggt gataaccctg agtctgaggg acttgactct
     4441 cttcgaacga tgtatggtga tgcgggcgag tcagctgttg ccagtgaaga agaaaagcat
     4501 aacctgtctt attggcaact catctggaaa tacgtttttt gtaacccgtc gctcttactt
     4561 gttgctgctg tcaatgtggc cctttatttt gttcgttttg ggattgaaga ctggatgccg
     4621 atctacttgt cgcaagtagc caatatgtca gaggctcata ttcattttgc gatttcaatg
     4681 ttagagtggg tagctattcc aggctccctg gtatttgcgt ggttagcggt tcgttatcct
     4741 aataaaatgg ccaagattgg ggctattgga ctttttgtgt tggcggctat tgtctttgtc
     4801 tatgaacgct tgactgccac aggtgctcca aactatttct tgttgcttgt tattgcaggt
     4861 attttagggt cattgattta tggcccacaa ttgatcgtga atattttaac aatcaatttt
     4921 gttcctttaa atgttgcagg aacagcgatt ggttttgtag gagtaacagc ttatctcatc
     4981 ggcaatatgg gagcaaactg gctgatgccg attttggcag atggttttgg ctggttttgg
     5041 tcatatattg tcgttgcagc cttatctgct ttttcagcgg ttggttattt gattttagcc
     5101 aaacgtgagg aagaaatcat caaagattag ctaggcaaat gcctaagaaa gacagactta
     5161 ttgctgaagt cctgtctttt ttagtcataa taagccgcaa atgacactat aaaagacaag
     5221 aaaatgctag gatgtttcag gaaaaaaaga gaaaatatgc tataatgaga aggtatttaa
     5281 attatatagt aaggaaaaac aaatgacaaa ttatgccatt attttagcag cgggcaaagg
     5341 gactcgcatg acttctgatc tcccaaaagt tcttcataaa gtatctggac taaccatgct
     5401 tgagcatgtt tttcgtagtg taaaagcgat tagtcctgaa aaagccgtga cggttattgg
     5461 tcacaaatca gaaatggtac gtgctgtctt agcagatcaa tcagcctttg tccatcaaac
     5521 agagcagtta ggaactggcc atgccgtgat gatggcagaa acacaattag aaggactaga
     5581 agggcatacc ttggtgattg caggagatac tcccttgatc actggagaaa gcctgaagag
     5641 tctgattgat tttcatgtga atcacaaaaa tgtcgccact attttaacag ctacggctca
     5701 agatccattt ggttatggtc gtattgttcg caacaaagat ggcgaagtga tcaagattgt
     5761 tgagcaaaaa gacgccaatg agtatgagca acaattaaaa gaaatcaata caggaaccta
     5821 tgtgtttgat aacaagcgtc tctttgaagc gctcaaatgc atcactacca acaatgctca
     5881 aggagagtat tacctgactg atgttgtggc tatttttaga gcaaacaaag aaaaggtagg
     5941 agcctatatc ctgagagact ttaatgaaag tcttggtgtt aatgatcgtg tggccttagc
     6001 aacagctgaa acagtgatgc gtcagcgcat tacccaaaaa catatggtca atggggtgac
     6061 tttccaaaat cctgaaaccg tttatattga aagcgatgtt gagattgcac cggatgtttt
     6121 aattgaagga aatgtgacct tgaaagggcg tacacatatc ggctcaggaa ctgtcttgac
     6181 gaatggtact tatattgtgg attctgaaat tggtcaagga agtatcatca ccaactcaat
     6241 gatcgaatca tctgttttag ctgcaggagt tacggttggc ccttacgccc accttcgacc
     6301 aggaacgacc ttagataggg aagtccatat cggtaacttt gttgaggtca agggttctca
     6361 cattggtgaa aaaacaaagg ctgggcatct gacttatatt ggaaacgctc aggttgggtc
     6421 ttcagttaat gttggggctg gaaccatcac tgtcaactac gacggccaaa acaaatatga
     6481 aacagtcatt ggagatcacg cttttattgg gagcaactcg actctcattg caccactaga
     6541 aatcggggat cacgctttaa cagcagcagg ttcaacgatt tcaaaaacgg ttcctatcga
     6601 tagcattgct attggtcgta gccgccaagt cacaaaagaa ggttatgcca agcgcctagc
     6661 gcatcaccca agtcgaagca aataattcaa gatctattta gtaaggaggc caggcatgaa
     6721 atttgaagaa aaaacgctta agagacaaac agtttttgat ggtcatattt ttaaagttgt
     6781 tgtggatgat gttgaacttc ccaacaatct ggggcaatcc aagcgagaat taatttttca
     6841 tcgtggtgcc gttgctgttt tggctattac tcctgaacgt aagattgtcc ttgtcaaaca
     6901 ataccgtaag gctattgaac gtgtctcata cgagatccca gcgggtaagc tagagattgg
     6961 tgaggaaggc tcaaagctaa aagctgctgc acgtgagcta gaagaagaaa cagcctatac
     7021 ggggacattg acgtttttgt atgaatttta tacagcgatt ggtttttgca acgaaaaaat
     7081 cacacttttc ttagcgacag acctaacaca agttgccaat cccaaacctc aagacgacga
     7141 tgaagttatc gaggtcttag agttgacata tcaagagtgc atggacttag tcgctcaagg
     7201 taaacttgct gacgctaaaa cgtttattgc tttgcaatac tatgccttac attttggagg
     7261 tgagcagtga tgggaaggcc attgttgacc gatgatatca tcgaaaaagc gagacgaatg
     7321 gaaacatttg agccagatga tgctgtagac tttgacacaa aagtaatgac gctaccagaa
     7381 aaagatgata aagcacgcat ttataaaagt cgtcggattg aaaatgccaa acgcagccaa
     7441 ttgcaatcta aattaaatgt gattttgata gctgttatgc tgttaattgc catcttggta
     7501 tatgctatct tttatcttta aaaaacgtaa ggaaataata tgaaaatagg aattattgct
     7561 gctatggagg aggagttgtc cctgctctta gcaaatctct tggatgctca agaacatcag
     7621 gtgctttcaa aaacttacta tacgggtcgt tttggcaagc atgagctcat tttggtacag
     7681 tcaggtgttg gaaaagtgat gtctgctatg acagttgcga tcttggttga gcatttcaaa
     7741 gcccaagcta ttatcaatac aggatcagca ggggcagtcg cttcacattt agcgatcgga
     7801 gatgtggtgg ttgcagatcg gttagtgtat catgatgtgg atgctactgc atttggttat
     7861 gcttatggtc aaatggctgg tcaaccatta tactatgatt gtgatccaca gtttgtggct
     7921 atcttcaaac aagtcctaaa acacgaaaag acaaatggcc aagttggttt gattgcaaca
     7981 ggagacagtt ttgttgctgg tcaggacaag attgaccaga tcaaaacagc ttttagcgac
     8041 gtgttagcag tagaaatgga aggcgcagct attgctcaag cagcacatac tgcaggtaaa
     8101 cctttcatcg ttgttcgtgc gatgagtgat accgcagcgc atgatgccaa tattactttt
     8161 gatcaattta ttatagaagc tggcaagcgt tcggcccaga tattaatgac atttttagaa
     8221 aacttacctg tttaactcac tttatcgtga gacaattagc tggataatct ctattttagg
     8281 agtctggtca cctcttgttt tgaaacctaa aaataagaat tgcaatcact tgaccaaacg
     8341 ctataatggg ttaagtaacg atagattact aaaaggagtc tcaaaatgac actaaaaaaa
     8401 cactattatc ttctcagtct gctagctctt gtaacggttg gtgctgcctt taacacaagc
     8461 cagagtgtca gtgcacaagt ttatagcaac aaaggatatc accagcattt gactgatcca
     8521 aaatcacacc tgcaatatag caaagacaac gcacaacttc aattgagaaa tatccttaac
     8581 ggctaccaaa gtgacctagg gaaacactac tctagctatt attactacaa cctaagaacc
     8641 gttatgggac tatcaagtga gcaaaagatt gaagaacact atgaaaagct taaagatgag
     8701 ctataccgca tatacaatca ttattaagtc aaaggcttaa aaatggagac tagcccctca
     8761 aaaaaagagg ccacactcat ttaaatttaa atgagtgtgg cctctttttg aggagacgca
     8821 aggggttaaa gggctgtgac ataaagttgc ttagcaatat tttcagggat gacaagttcc
     8881 ttgtcgccat aacaaatcgt ataggttttt gcaaaggtat caatttgagt taaggttagc
     8941 tcggtattaa tattgaggtg atgtgcttct agatactgga ttaaatcaaa gtggtcgtgg
     9001 attctgctta ggcgaaaccg tcccaactcc gtgatggtgt tgagagttgt agtgttcatt
     9061 tcgacaagag gctgaccata gcgaggaata gtccctccgt gtgggcagaa atctggaaaa
     9121 ttaaggattt tgtctaaacg gtcgataaag gtgtctgaga cagtgtgctc taagacttca
     9181 gcttcttggt gcacttcttg ggtattatag cccagctggt gaatcaaaaa tacctcaatc
     9241 aagcggtgtt tgcggtagag gttagcaaca agagcatagc ctttgtcttt tagcaaatag
     9301 ccttttgctt tatctttgac aatccagcct tgtgaaatca tttttttaat catctctgaa
     9361 acggcaggtg ccgaaacgtg catcttttct gcaaccattt tatttgtaat cttgggttct
     9421 tgttctccaa tttcataaat acatttcaag taatcttctt tattaggcgt catatcgttt
     9481 ggcctttctc ttatttataa tgattattat atcagaattt ttaggaaaaa gcttgacaaa
     9541 aagcctaaaa gaggatatcc ttatagcata attaactaaa cttaattaaa taaataacat
     9601 atcctaagga gagaaatgat gggaaagaga atgagcctca ttttgggtgc ttttttatct
     9661 gtttttcttt tagtagcttg ttcgtcaact ggtactaaaa ctgctaagag tgataaatta
     9721 aaagtcgtgg caaccaattc aattattgcc gacatgacaa aagctattgc tggtgataaa
     9781 atcgatctgc acagcattgt accaatcggt caagatcctc atgagtacga accattacca
     9841 gaagatgttg aaaaaacaag taatgctgat gtgattttct ataatggtat caatctagaa
     9901 gatggtgggc aagcttggtt cactaaacta gtgaaaaatg ctcaaaaaac gaaaaacaaa
     9961 gattactttg ccgtgtctga tggcattgat gtgatttact tggaaggtgc aagcgaaaaa
    10021 ggaaaagaag acccacatgc ttggttaaat ctcgaaaacg gaatcattta ttcaaaaaac
    10081 attgccaaac aattgattgc aaaggatcct aaaaacaaag aaacttatga aaagaatcta
    10141 aaagcttatg tggctaaatt ggaaaaacta gacaaagaag ccaaatcaaa atttgatgct
    10201 attgcagaaa ataaaaaatt gattgtgact agtgaaggct gcttcaagta cttttcaaaa
    10261 gcttacggtg tcccatctgc ttatatctgg gaaattaaca ccgaagaaga aggaacacca
    10321 gatcaaattt catcattgat tgaaaaacta aaagtcatca agccatctgc gctttttgta
    10381 gagtcaagtg ttgatagacg ccctatggaa actgtttcta aagatagtgg tattcctatt
    10441 tattctgaga tctttacaga ttcaattgct aaaaaaggta aacctggcga tagttattat
    10501 gctatgatga aatggaacct tgacaaaatt tctgaaggtc tagcaaaata agataacaat
    10561 aaagcacagc gattttagtg ttgtgctttg ttttatttat gtaaaggaga caaaatgatt
    10621 acaactaaca atctttgtgt gacctacgat ggcaacagta atgctttaga agcgattaat
    10681 gtgacaattg aaggtccttc tatcgttggt attatcggtc ctaatggagc tggaaaatca
    10741 acctttatga aagctatctt aaatcttatt gattatcaag gtcacgtaac ggttgatggc
    10801 aaagatggtc gtaagcttgg gtatacagta gcttacgtag aacaacgaag catgattgac
    10861 tataattttc ctattactgt taaagaatgt gtggcgctag ggacttatag taaattaggc
    10921 ctttttcgcc gagtaggaaa aaaacaattt gagcaggttg ataaggttct caaacaagtt
    10981 ggtttagaag actttggcca tcgaccgata aaatccttat ctggtggtca gtttcagcgg
    11041 atgttggttg cacgttgctt gattcaagaa tcagactata ttttcttaga tgaaccgttt
    11101 gttggcattg actcggtcag cgaaaaaatc attgtagatc ttttgaaaga gctcaaaatg
    11161 gctggcaaaa cgattttaat tgtacatcat gatttgagca aagtagagca ttattttgac
    11221 aaactcatga ttttaaataa acatttggtg gcttatggca acgtttgtga ggtatttact
    11281 gttgatacct tgtcaaaagc ttatggcaat catttgattt taggaaagga gatggtgtaa
    11341 atgtctatga aattttttga gggcttgatg tcataccact ttttacaaaa tgcactgata
    11401 acggctgtag tcattggtat cgtctcaggt gctgtagggt gttttattat ccttaggtca
    11461 atgtctctta tgggtgatgc catctcacac gctgttttac caggggttgc tttgtcattt
    11521 attttaggag tcaatttttt tattggagcg attatttttg ggttattagc ttctgttatt
    11581 attacttata tcaaggaaaa ttctgtcatt aaaggagata cggctattgg tatcaccttt
    11641 agctcttttt tggcactggg agtcatcttg ataggggtag ccaatagttc gacggactta
    11701 tttcatattt tgtttgggaa tattttagct gtgcaagata gcgataagtg gattactatt
    11761 ggtgtttcga tttttgtttt aggggttatt agtctctttt tcaaagaact attattaaca
    11821 tcatttgatc ctatcttagc caaatcaatg ggtgtgaagg tcaatgcgta tcattatttg
    11881 ttgatggtcc tattaacttt agtggctgtt acggcgatgc aaagcgtggg tactatcttg
    11941 attgttgcct tactgattac gccagcagcg acagcttatt tatatgctaa tagcttaaaa
    12001 gtaatgttag tgatgtcatc tttactaggc gctttagcat cggttttagg gctttatctg
    12061 ggctatacct ttaatgttgc cgcagggtca agtatcgtac tgacttctgc gatgatgttt
    12121 ttgatcagtt tctttgtttc acccaagcaa ggctacctca aaagatggat gcaaaaaaaa
    12181 gaaaaaacac cttaaacttt tcgctttaaa caccttagtg gtttgcaaat agtggcaaat
    12241 gacatcaaag ggtgtttttt atatgtcatc aaaagaccat aaaaaacctt atcaaaccaa
    12301 ggtatttagc ctattatctg ataaggtttt tttaagcatg atttagtttt taaagcgata
    12361 atctttgaca atgtcaattg aggtaatcgt aatgtcttgt tctggtttat cattttggtt
    12421 gatagaagtc gcggcaattt tatcgacaac atccatacca tcaatgactt gaccaaatac
    12481 agtataaccg ccatctaagc ttggattgcc gccatgctca taggcagaga tgataggttt
    12541 tgggtagttg gtacttgata atcccttgct ttgatttttc ttgttttggt tgatataaaa
    12601 ttggctaccg ttcgtattag cgccagcatt tgccatggca agagcaccgc gaatatgata
    12661 taaaaatgga gagatttcgt tgacaaagcc attgccagca tcttttttag gatccttgcc
    12721 cttccaaatc gattcaccac ctgtgccatc tcctttgggg tcacctgatt gaatcataaa
    12781 gtcgttgatc acacgatgga aggtaaggtt atcatagtag ccttttttag catgggtgag
    12841 gaagttctca acagctaagg gagcatattt tgggaataac ttaagggtga tgtccccttg
    12901 acttgtcctc attacgacct tagcttcttc tttgccgact tctttggtta gttgtggaaa
    12961 ttggctagca tcagctttga gagctttttg aatgctttct tcataggctt tagaagctgc
    13021 ttcgctttct tctttggcag ttttttcatc aatgtattta ttgcctttta tagcgcggtc
    13081 aacatattca caagcactca aactaagtaa actaatggct actaaactga gagataataa
    13141 ttttttcatg tctactccta agaatgattt tctttatttt atcataaaat gcaacagaaa
    13201 atagtagtaa agagttaaaa acgcctattt ttgtgtttta tgatctaacc ttggttaaaa
    13261 ggctgctacg actgttatta tagcacaaga tgctatagaa aaacttaaaa caccttggtt
    13321 ttttagagct atttcctaat agttaaaaaa tggtataata gtgttatggt taaaagaaat
    13381 caaagaaaaa aaagtgcgcc taagaagcgt ttaacaaaag cagaagtgga aaagcaacgt
    13441 gccattaaga ggatgatttt atctgtttta atggctttgt tgcttatttt tgcgatgctt
    13501 cgcttgggcg tctttggcgt gacaacctat aatatgattc gttttttggt gggtagttta
    13561 gcctatccgt ttatgttttc ctggttaatt tacttatttt gttttaaatg gttacggcaa
    13621 aaagatggaa tgattgcggg agttgttatt gcctttttgg gattgctagt tgagtggcac
    13681 gccttcttat ttgcgatgcc taggatgctt gatcaagata tttttctagg cactgctcgg
    13741 ctaattacaa gagatttact agccctgcgc gtgactgaat ttgttggtgg aggaatgctt
    13801 ggtgcattac tttataaacc catagccttt ttattttcga atatcggctc ttactttatt
    13861 ggttttttgt ttatcttatt aggattattt ctaatgacgc cttgggatat ctatgatgtg
    13921 agtcactttg tgaaagaggc tgttgataaa ctagcagtgg cttatcagga aaataaagaa
    13981 aagcggttca tcaaacgaga agagcaccgc ttacaagctg aaaaagaggc tttagagaaa
    14041 caagcacaag aggaagaaaa acgtctagca gaattgacgg ttgatcctga gactggagag
    14101 attgttgagg atagtcagtc tcaagtcagc tatgatttgg ctgaggatat gccaaaagag
    14161 ccagagattc ttgcttatga tagtcacctc aaagacgatg aggcaagctt atttgaccaa
    14221 gaagacttgg cttacgctca tgaggaaatt ggggcttatg actctttatc tgctttagca
    14281 tcttctgaag atgagatgga tatggatgaa cctgttgaag ttgatttcac accaaaaacc
    14341 catcttcttt ataaacttcc aacgatagat ttatttgcac cagataggcc caaaaaccag
    14401 tccaaagaga aaaacttagt ccgcaaaaat atcaaggtgc ttgaagatac cttccaaagt
    14461 tttgggattg atgtcaaggt agaacgagca gaaatcgggc cttccgtcac caaatatgaa
    14521 atcaagccag ctgtcggggt ccgagttaat cgtatttcaa atcttgctga tgatttggca
    14581 cttgctctgg ctgctaaaga tgttcgtatt gaagcaccaa ttcctggaaa atccttaata
    14641 ggtattgaag ttcctaactc agaaattgca acggtttctt tccgcgaact ttgggaacaa
    14701 tctgatgcta atcctgaaaa ccttttagaa gtaccactag gaaaagctgt taacggcaat
    14761 gctcgcagtt ttaacttagc tagaatgccg catcttttgg tagctggttc aactggttca
    14821 ggtaaatctg tggcagttaa tggcattatt tcaagtattt tgatgaaggc acgtccagat
    14881 caagttaagt ttatgatgat tgaccccaaa atggttgaat tatctgttta taatgatatt
    14941 ccacatttat taatccctgt tgtaaccaat ccgcgtaaag ccagtaaggc actccaaaaa
    15001 gtggttgatg agatggaaaa ccgctacgag ttatttagta aaattggtgt gcgtaatata
    15061 gcaggttata atacaaaggt tgaagagttt aatgcttctt ctgagcaaaa acaaataccg
    15121 ttgcctttaa tcgttgtcat tgtagatgaa ttggctgact tgatgatggt ggctagtaaa
    15181 gaagttgaag atgctattat tcgtttggga caaaaagcac gtgctgcagg tatccatatg
    15241 attcttgcaa ctcaacgtcc ctctgtagat gttatttctg gtttgattaa agcaaatgtt
    15301 ccgtcgcgta tggcatttgc tgtttcaagt ggtactgata gccgtacaat ccttgatgaa
    15361 aatggtgctg aaaagctctt gggacggggt gatatgctct ttaagccgat tgatgaaaat
    15421 caccctgttc gcttgcaagg gtctttcatc tcagatgatg atgtggagcg tattgtcaac
    15481 tttatcaaag accaagctga agcagattat gatgacgcct ttgatcctgg tgaagttagc
    15541 gacaatgatc ctggtttttc tggaaatggc ggagctgctg aaggtgatcc tctttttgaa
    15601 gaagcaaaag ccttggtctt agaaacacaa aaagctagtg cctcaatgat tcaaaggcgt
    15661 ttgtcggttg gatttaatcg tgccacgcgc ttgatggatg aattggaaga agcaggtgtt
    15721 atcggtccag cagaaggaac caaacctcgt aaggtattgc agacaaacta aaagaacctg
    15781 acgtctcatc atgagatgtc aggttctttt tttgtgatgt caagccagtt gatgagatgc
    15841 ctatgctaat gtaaaaataa agataactag aatcagatag aaaataacgg tgactaaaaa
    15901 gccaactcgc caaaatagct tcataaagcg atggtaagaa aacgactgag ttcggatgac
    15961 tagcagtagt gaaatgacga tggctagcag cgacatgata ataagataat aaggcagtaa
    16021 attatgggtg aaaaattttc ctgagacaag cacaatttct atcgcaaaaa gtaaaagtgc
    16081 gacatctgga aatttaaatc cctttttatt aagtttaaat aaagaggtta caatcatggc
    16141 aaaaagaggc gttactatca agaaagctaa ggcagttaat ttatagatca tcataggtct
    16201 attttatact taaatccctt acttgtaaac tgatacttac ctgttgtgat agaaactgat
    16261 ctttgagatg gaaagagcct acttcaattt aaacattgca aaaggcatca gctattttaa
    16321 caaaaagact tgatttattt tggcaataag ctataatggt aaggtatgca atattgcata
    16381 tctgtgggag gtaaaaatct caattaccgc caaaaccaca acaggaggat ttttaaaatg
    16441 gctaaaaaag tcgaaaaact tgtaaaactt caaatccctg ctggtaaagc tacaccagct
    16501 ccaccagttg gaccagctct tggtcaagca ggtatcaaca tcatgggctt cactaaagaa
    16561 tttaacgctc gtacagctga tcaagctggt atgatcatcc cagttgttat ctcagtttat
    16621 gaagacaaat catttgattt catcactaaa acaccaccag ctgctgttct tttgaaaaaa
    16681 gctgcaggtg ttgaaaaagg atcaggtaca cctaacacta ctaaggttgc gacagttact
    16741 cgtgcacaag tacaagaaat tgctgaaact aagatgccag atttgaacgc tgcaaacatt
    16801 gaagctgcaa tgcgtatgat tgaaggtact gctcgttcta tgggattcac tgttactgac
    16861 tagtcagtca agaaccccta ttacccgcac gacttcatca taagagatga gtgacgtggg
    16921 agattttaaa tcaaatcgat atgaccacat tacaaggaga attttaaaat ggctaaaaaa
    16981 agcaaacaaa tgcgtgctgc acttgaaaaa gtagatagca caaaagcgta cagtgtagaa
    17041 gaagctgtag cattagtaaa agaaacgaac ttcgcaaaat ttgatgcgtc tgttgaagtt
    17101 gcttacaact tgaacattga cgttcgtaaa gcagaccaac aaatccgtgg cgcaatggta
    17161 ttgccaaacg gaactggtaa aacacaacgt gttcttgttt ttgcacgtgg tgcaaaagct
    17221 gaagaagcaa aagcagctgg tgcagacttc gtaggtgaag acgaccttgt tgcaaaaatc
    17281 aatggtggat ggcttgactt tgacgttgtt atcgcaacgc cagacatgat ggctatcgta
    17341 ggtcgtcttg gacgtgtcct tggacctcgt aacttgatgc caaaccctaa aactggtaca
    17401 gtaacgatgg atgttgctaa agccgttgaa gagtctaaag gtggtaaaat cacttaccgt
    17461 gctgacaaag caggtaacgt acaagctctt attggtaaag tttcatttga tgctgacaaa
    17521 ttggttgaaa acttcaaagc cttccacgat gtaatggcta aagctaaacc tgcaacagct
    17581 aaaggaactt acatggcaaa cgtctcaatc acatcaacac aaggtgttgg tatcaaggtt
    17641 gatcctaact cactttaaga aaaaaattag ggcatcgcct aatcatagca aaaagacaaa
    17701 tttctgaaga caaatcttca ctagaggttt gtctttttta tggtttaaaa tggaatgcaa
    17761 acaaaaaagt gtaggcgata ataccatgaa aggagttgat tctcttaatg agatgtggtg
    17821 ttaacacatc atgagctcac aaaaaatgat aaaggaagta tcggtggtgt taaaaaaggg
    17881 attttaattg acatttatta gcctctaaaa tgtcctttcc ctattcataa ttgagggttt
    17941 gtggtaaaat agtaaggaca aactaaggag aacatagtag tggaacctaa atatcaacgt
    18001 atattaatta agttatctgg tgaagcatta gcaggtgaaa aaggagttgg cattgacatt
    18061 ccaactgttc aggctattgc aaaagaaatt gccgaagttc atgtgtcggg agtacagatc
    18121 gctcttgtta ttggtggagg caatctctgg cgtggagagc ctgcagcaga cgctggaatg
    18181 gaccgtgttc aggctgatta cactggcatg cttggaacgg tgatgaatgc cctagtcatg
    18241 gctgatagtc ttcaacatta tggtgttgat acccgtgtgc aaacagctat tcctatgcaa
    18301 aatgtagcag aaccttatat tcgcggacgt gccttgcgcc atctagaaaa aaatcggatt
    18361 gttgtttttg gagctggtat tggctcgcct tatttttcaa cagacaccac cgcggcactg
    18421 cgtgctgctg agattgaagc agatgctatt ttaatggcaa aaaatggtgt ggatggggtc
    18481 tataatgctg atcctaaaaa agatgctaat gcggttaaat ttgatgaatt aacacatggt
    18541 gaagtgatca aacgtggtct caaaatcatg gatgcaacgg catcgacctt atcgatggat
    18601 aatgatattg atttggtggt tttcaatatg aatgaagctg gcaatattca acgtgttgtc
    18661 tttggagaac atattggaac tactgtatca aataaagttt gtgactaaaa gttagaaaag
    18721 aaagagagta attatcatgg caaatgcaat tattgaaact gcaaaagaac gttttgcaca
    18781 atcccatcag tctttatcac gtgaatatgc cagcattcgt gcgggtcgtg ccaacgctag
    18841 tcttttagac cgtatccaag ttgattatta cggggcaccg acaccattaa atcaattggc
    18901 ttcaatcact gtaccagaag cgcgtgtctt attgatctcg ccttttgata aatcttctat
    18961 caaagatatc gagcgcgctc ttaacgcatc agatttaggc attacacctg ctaacgatgg
    19021 ctctgtcatt cgtttggtta ttccagcttt gaccgaagaa acacgtaaag aattagccaa
    19081 agaagtgaaa aaagttggtg aaaatgctaa aattgcaatc cgtaatatcc gccgcgatgc
    19141 tatggatgat gctaaaaagc aagaaaaagc aaaagaaatc actgaagatg agttaaaaac
    19201 acttgagaaa gatatccaaa aagcaaccga tgatgctatc aaagaaattg accgcatgac
    19261 ggctgaaaaa gaaaaagaat tgctctcagt gtaacaggat ttctacgaaa aatagacgac
    19321 tatagacaca aaaagatagg tgaccatttc agaagcgttt ggttttgatt tgtccctatt
    19381 tttttaaaga aagaaaaaag atatgaatga tttactagca acagtcatta ctgggcttat
    19441 taaagaagaa aacgctattg actattttat ccaaaaagaa gggtttacct ttaccttgtc
    19501 taaagcagaa ggagaacgcc agattggtga tatggtcaca ggctttgcct atacagacat
    19561 aaagcaaaag gcacgtctca caaccaaaga gatccgttca acacggacaa gttatggctg
    19621 gggagaagtg acagaggttt gtcgtgacct aggcgttttt gtcgatacag gaattccaaa
    19681 taaagaaatt gtggtttctt tggacgtgtt gcctgaaatg aaagaactat ggcctaaaaa
    19741 aggggataaa ctttacattc gtttggatgt ggataaaaaa gaccgtattt ggggacttcc
    19801 agcagagcct gaggtctttc aaaagatggc tagccctgct tacaataaca tgcaaaatca
    19861 acattggcca gcaattgttt accgcctaaa attaacagga acttttgttt acctgcctga
    19921 aaacaacatg ttgggcttta ttcacccaag tgaacgctac gcagaaccgc gcttaggtca
    19981 ggttttagat gcccgtgtga ttgggtttag agaggtcgat cgtaccttaa acttgtcgtt
    20041 gaaaccacgt tcttttgaga tgttggagaa tgacgctcag atgattgtta cttatctgga
    20101 agccaatggt ggtttcatga ccttaaatga caaatcaagt ccagaagaga ttaaagcaac
    20161 ctttggtatt tcaaaaggcc agtttaaaaa agccttgggt ggattgatga aagctaaacg
    20221 catcaaacaa gacgccacag gaactgaatt aataggataa aaatgctttg ccactggcaa
    20281 agttttttgt tacaatgaag gccattaagt gaagaaaaag gggatataga gaatggaaag
    20341 agccattttt gcaggaggtt gtttctggtg tatggtgcaa ccttttgagg agcaagcagg
    20401 tattttgtca gtcagaagtg gctacacagg tgggcatctc ccaaatccta gctatgaaca
    20461 agtttgtgcc aaaacaacag gacatacaga agctgttgaa attatttttg accctaagca
    20521 aatcgcttat aaagatttgg tagagctcta ttgggcgcag acggatccaa cagacgcctt
    20581 tgggcaattt gaagatcgtg gggacaacta ccgtcctgtc atttactaca caacggaaag
    20641 acaaaaagaa attgcagagc aatcaaaagc aaacttgcaa gcttcaggac gttttgacca
    20701 acccattgtc accactattg aaccagcaga gccattttat ctcgcagagg attatcacca
    20761 aggattttat aaaaagaatt ccaagcggta tgcacaaagc agtgctattc gtcatcagtt
    20821 tttagaggag aattggtcat gagaaaatca ttttacagct ggctgatgac acaacgtaac
    20881 cctaaatcaa atgaacctgt ggcgatttta gcagatttgg tgtttgatga caccactttt
    20941 ccaaagcata ccaatgattt tgaactcatt agtcggtatc tagaagatca agctagtttt
    21001 tcctttaatt taggtcaatt tgatgaaatc tgggaagatt atctagcaca ttaatacgtg
    21061 gataaaaaag agtcatatcg actcttttga agggttatca cgttattatt acaaaatgac
    21121 atcactttct ttcaaaaaaa tgacaagcta ctttttttct taaaaatatg ctatgatata
    21181 gcttagaaaa aaataaaaag gaagcagaga tgattattac taaaaagagc ttatttgtga
    21241 caagtgtcgc tttgtcgtta gcacctttgg cgacagcgca ggcacaagag tggacaccac
    21301 gatcggttac agaaatcaag tctgaactcg tcctagttga taatgttttt acttatactg
    21361 taaaatacgg tgacacttta agcacaattg ctgaagcaat gggaattgat gtgcatgtct
    21421 taggagatat taatcatatt gctaatattg acttaatttt tccagacacg atcctaacag
    21481 caaactacaa ccaacacggt caggcaacga ctttgacggt tcaagcacct gcttctagtc
    21541 cagctagcgt tagtcatgta cctagcagtg agccattacc ccaagcatct gccacctctc
    21601 aaccgactgt tcctatggca ccatctgcga caccatctga tgtcccaacg acaccattag
    21661 catctgcaaa gccagatagt tctgtgacag cgtcatctga gctcacatcg tcaacgaatg
    21721 atgtttcgac tgagtcgtct agcgaatcac aaaagcagcc agaagtacca caagaagcag
    21781 ttccaactcc taaagcagct gaaacgactg aagtcgaacc taagacagac atctcagaag
    21841 gcccaacttc agctaatagg cctgtaccta acgagagtgc ttcagaagaa gtttcttctg
    21901 cggccccagc cccagcagaa aaagaagaaa cctctgcgcc agcagcacaa aaagctgtag
    21961 ctgacaccac aagtgttgca acctcaaacg gcctttctta cgctccaaac catgcctaca
    22021 atccaatgaa tgcagggctt caaccacaaa cagcagcctt caaagaagaa gtggcttctg
    22081 cctttggtat tacgtcattt agtggttacc gtccaggtga tccaggagat catggtaaag
    22141 gtttggccat tgattttatg gtgcctgaaa attctgctct tggtgatcaa gttgctcaat
    22201 atgccattga ccatatggca gagcgtggta tttcatacgt tatttggaaa cagcgattct
    22261 atgcgccatt tgcaagtatt tacggaccag cctacacatg gaaccccatg ccagatcgcg
    22321 gcagtattac agaaaaccat tatgatcatg ttcatgtctc ctttaatgct taattcatgc
    22381 tatcaaaaaa actcacgttt aggcgtgagt tttttgacaa ttctgacaga gtaagcccta
    22441 taagaggctg agatacgctt ttaatacctg ttgtttttct caccctttag acagttttaa
    22501 cgttatgtct aaaagagatg gtttttatta gcgcaaatat gggtttaggg gtaaaataaa
    22561 ggtaattaac ctgatatgat catgataaag gtagaagaat acctattatt tcgtgacaac
    22621 tgagcaatct gccttacctt tggagtgatg atatcacttt gcttgactat tcaaggaggt
    22681 cttgaaatgt attatactag tggtaattac gaagcttttg cgacacctcg aaaacctgaa
    22741 aaggtagatc agaaatcagc ttatattgtt ggtactggct tagctggttt agcagcagct
    22801 gttttcctta ttcgcgatgg gcatatgact ggggaacgca ttcatctgtt tgaggaattg
    22861 cctttagcag gtggttcttt agatggtatt gaaaagcctc atcttggttt tgtgacccgt
    22921 ggtggtcgtg agatggaaaa tcattttgag tgtatgtggg acatgtatcg gtctattccc
    22981 tcactggaaa ttcccggtgc gtcttattta gatgaatttt attggttgga taaggatgat
    23041 cctaactcat ccaactgtcg tttgattcac aagagaggaa atcgtgtgga tgatgacggc
    23101 cagtatacgc tcggtaaaca gtcaaaagaa ttaatccatt taatcatgaa gacagaagaa
    23161 tccctaggag accaaaccat tgaagagttc ttctcagaag atttctttaa gagtaatttt
    23221 tgggtgtatt gggcaaccat gtttgctttt gaaaaatggc actctgttgt agaaatgcgg
    23281 cgctatgcga tgaggtttat ccaccatatt gatggtttgc cagattttac ctccctcaag
    23341 ttcaacaaat ataaccaata tgactctatg gtcaaaccga ttattgctta cctagaatca
    23401 cacgacgttg acatccaatt tgacacaaaa gtcactgata ttcaggtgga acaaacagct
    23461 ggtaaaaagg tagcaaaaac catccatatg acggtgtctg gggaggctaa ggcgattgag
    23521 ctaacacctg atgatttggt ttttgtgacc aatggttcta ttactgaaag tagcacatac
    23581 ggtagtcatc acgaagtggc taagccaacc aaagcgttag gtggttcttg gaatttatgg
    23641 gaaaatctag ctgctcaatc agatgatttt ggtcatccta aagtgtttta ccaggacttg
    23701 cctgctgaaa gctggtttgt gtctgctaca gcaaccataa aacacccagc tatcgagcct
    23761 tatattgaac gtttgaccca ccgtgacttg cacgatggca aagtgaacac tggcggcatc
    23821 atcactatta cagattctaa ctggatgatg agctttgcca ttcaccgtca acctcatttt
    23881 aaagaacaaa aagaaaatga gaccactgtc tggatttacg gtctttattc caatagtgag
    23941 ggcaattacg tccacaagaa aattgaggag tgtacaggtc aagaaatcac agaagaatgg
    24001 ttgtaccacc ttggggtacc tgttgataaa atcaagggct tagcgagtca ggactatatc
    24061 aatacagttc ctgtttacat gccttatatt acgagttact ttatgccacg cgtcaaagga
    24121 gaccgtccga aagttatccc agatggttca gtcaacttgg cctttattgg taactttgcg
    24181 gaatctccat ctcgagatac ggtctttacg actgagtatt ctattcgtac tgccatggaa
    24241 gcagtgtata gcttcttgaa tgtggaacga ggcatcccag aagtctttaa ttcagcctat
    24301 gatattcgtg aattgctcaa agccttttat taccttaatg ataaaaaggc aatcaaggat
    24361 atggatttgc caattcctgc actgattgag aaaatcggac ataaaaaaat caaggatacc
    24421 tttatcgaag aattgctcaa agatgctaat cttatgtaac atgccttaga gtagttaaag
    24481 ctgataagtt taggcttatc agcttttttg atgatttata gaaaagtgat aaaggaaaag
    24541 tctgacgtga acgtcacata agaatttaaa atttgttata atgtaagcaa taaagatgaa
    24601 agaaagaggg actctatttg caagagtatt ctattgacat taccttaact catcctgatg
    24661 atgttttagc tctttttggt agcaacgagc gtcatttgaa gctaatagaa gctcatttag
    24721 gagttattgt tcacgcaaga accgagcgag tccaagtgat tggtgatgat gaagaagctg
    24781 tggaattggc tcgattgacc atcaaagccc tactggttct agtgggtcgt ggcatggtgg
    24841 tcaacacatc agatgtggtg acagctttat ctatggcaga atctcatcag attgaccaat
    24901 ttatggcgct ttatgaagaa gaaatcatta aagataacta tggtaaggca atacgagtca
    24961 aaacattagg tcaaaaaacc tatgttgata gtgtcaaacg tcatgatgtg gtttttggtg
    25021 taggacctgc agggacaggg aaaaccttct tagctgttac gcttgcagtc actgctctga
    25081 aaagaggaca ggtaaagcgt attattttga cgcgtcctgc ggtagaagct ggcgaaagcc
    25141 taggtttttt accaggcgat ttgaaagaaa aggtggatcc ttacctcaga cctgtttacg
    25201 atgcccttta tcacatttta ggcaaggaac aaaccacacg cctgatggaa cgagatgtga
    25261 ttgagattgc tccgttagct tatatgcgag gtcgtactct ggatgacgct tttgttatct
    25321 tagatgaggc tcaaaacacg accatcatgc aaatgaagat gtttttgacc cgtcttggtt
    25381 ttaattctaa aatgattgtc aatggagata cgagtcagat tgacctccct cgaaatgtca
    25441 agtctggttt gattgatgct actcagaaat tacaaggcat taaacagatt gattttgtct
    25501 atttctctgc taaagatgtt gtccgacatc ctgttgtggc tgatattatc aaggcttatg
    25561 aaacgtcctc agaggagatg aaggacttac taaaacctaa ggctagtgac gttgaagctg
    25621 attaccagcc aggcttgaca aaataccctg tgatcggtca agagcactaa gacctttacg
    25681 atgatgttta atatggcctt tttaaggagg attctatgga tgatttaacc aaagctatta
    25741 tggcagatga ggctaatctc tcctataccg aaagaggtat ttttccttta tatgatgctc
    25801 ctcaaacagc taggattatt attgttggcc aagctcctgg aatagtagct caagaaacca
    25861 aactttactg gaatgatcgt agtggcatcc gcttacgaga ctggctaggt gtggacaatg
    25921 acacctttta ccactcagga ttgtttggca ttatccctat ggatttctat tatcctggta
    25981 agggaaaatc cggtgactta ccacctagag aaggttttgc ggctaagtgg cacccgccat
    26041 taagagcatt gatgccagaa gttgaattga cgattttggt tggtcgctat gctcaggact
    26101 tttaccttgg taacaaggct tacaaaacct taactgaaac agtccgtcac tttgaggatt
    26161 acttgccaga ctattttcca cttgttcatc cttctccaag aaaccaattg tggttagcta
    26221 agaacccctg gtttgagcag gatttattac ctatcttgca aaaacgtgtg gaggcaattc
    26281 taaccaaata ggccctgatt tacctagcat tcccattttt aaggggcttg tggtataatg
    26341 ggtaaataac aaatgctgat tgaaaggata agggaaatta tctgtcagat aataatgggt
    26401 gcccaacata ccaaatgagg tgggcagccc ttccctaaca attaacctta tgtatatcga
    26461 gatgattgac gaaacgggac aagtttcgca agagattatg gagcaaacac ttgatttgct
    26521 caattttgct gctcaaaaga cgggcaaaga agaaaaagaa atgtctgtga cctttgtgac
    26581 caatgaaaga agtcatgaac tcaacttaga ataccgagat actgatcgtc caacagatgt
    26641 gatttctcta gaatataagc cagaaacgcc tattttattt agtcaagagg atttggctgc
    26701 tgatcctagt ttggcagaga tgatggcaga gtttgatgct tatattggcg aattgtttat
    26761 ttctattgac aaggcgcgtg agcagtccca agaatatggg cactcttttg agcgtgaaat
    26821 gggattttta gctgttcatg gattcttaca tattaatggg tatgatcact acacccttga
    26881 agaagaaaaa gagatgttta ccttacagga agagattttg actgcttatg gccttacacg
    26941 acaataatac caccaaacgg aaatggaaaa acagaaccat tacctcaagc ttggagtttg
    27001 ccttgacagg ggttttcaca gcttttaagg aagaacgcaa tctcagaagt caccttttgt
    27061 ctgcctgttt agcttgtgtt gctggtttat tttttagcat ttcagccatc gaatggttat
    27121 ttttacttct agccattttt ttggtcatta ccttagaaat tgtcaattct gctattgaaa
    27181 atgtagttga tttggctagt gactatcact tttctatgct agctaaaaat gccaaggata
    27241 tggcagcagg tgctgttttg atgatttctg gctatgctgt cttgacagga cttattattt
    27301 ttattcctaa aatttggaat attttcgttc attaaaaaga aaggaatggg ctatcctatg
    27361 tgatgatggc ataggagaat aaggaaagga caagacggtt aagcttagtg acaagcttga
    27421 tctgaagccc taccgttaag gcccgtaatt atctatgttt aaatcaggct ttgtagccat
    27481 tcttggtcgt ccaaatgttg gcaaatccac ctttttaaat cacgtcatgg ggcaaaaaat
    27541 tgccatcatg agtgacaagg ctcagaccac ccgtaataaa attatgggca tttacaccac
    27601 agaaacagaa caaattgtct ttattgatac gccaggtatt cataaaccaa agaccgccct
    27661 tggtgatttt atggttgaat ctgcttatag tactttacgt gaagttgaga cggttctttt
    27721 catggttcct gccgatgaaa agcgtggtaa gggtgacgac atgattatcg agcggctaaa
    27781 agcagctaag attcccgtta ttttagtcat caacaaaatt gataaggttc atccagacca
    27841 acttttggaa cagattgatg acttccgtag ccaaatggat tttaaagaag tggtcccaat
    27901 ttctgcccta gaaggtaata atgtgccaac cctaatcaag ttattaactg ataatcttga
    27961 agaaggtttc cactattttc cagaagatca gattactgat catccagaac gtttccttgt
    28021 gtcagaaatg gttcgtgaga aggtactgca tttgacgcaa caagaggttc cacattccgt
    28081 agctgttgtt gtcgaatcca tgaagcgaga tgaagagact gataaagtgc atatccgtgc
    28141 aaccattatg gtggagcgcg atagccaaaa aggcatcatc attggaaaac aaggagccat
    28201 gctcaaaaaa atcggaaaaa tggcgcgccg tgatattgaa ctcatgttag gtgacaaggt
    28261 ctacttagaa acgtgggtca aagtcaagaa aaactggcgg gataaaaagc ttgatttagc
    28321 tgattttggc tataatgaga aagaatacta acatagtaaa gcgagatcat atgccacaag
    28381 actacatttc ttatatccgc tccaaagttg ggcatgataa gattattctt aactttgctg
    28441 gtgggatttt gaccaatgat gacggcaagg tgctgatgca gttgcgtggt gataagaaaa
    28501 cctgggctat tcctggtggc actatggaac tgggtgagag ctctttagag acttgcaaac
    28561 gtgagttttt agaggaaacc ggaattgagg ttgaagctgt tcgcttactg aatgtttaca
    28621 ctcattttga ggaagtttat cccaacggtg atgctgttca gaccattgtc tttatctatg
    28681 aactaacggc tgtttctgac atggctattg ataactttca taatgaggaa acgctcaagt
    28741 tacagttttt ctctcatgag gagatagcag agttagagag tgtctcagcc aaacatcgcc
    28801 tgatgttaga ggaatatttt agtgatagct ttgctatggg gcattaagaa ctctctagga
    28861 cagttggagt atttttggag attggcttgt taaaaaaatt tttgaaagac gatgtttcga
    28921 gagcttatgc tctctttttt tgcttccaat ttttctgatt aagtctgaat aattttgtta
    28981 aatgttaata ggattttctt tccaattgat actagcagac atcaaacatt tgttttagag
    29041 ttatgacgaa ttgccatcta gccatgcatg acttaggcaa gttgaaccta actgtggcaa
    29101 tagacttgga aggggtgaca agaaccattt cctaaaagaa ttgatgaagt gcctatccat
    29161 tattcgaatt gtaaagttcg tctaagtaaa gttgaatttg gtctcgaatg gaccttaatg
    29221 atttatgact tgttgtgtca ataacaccaa aaactcgata atgattttta aatatttcct
    29281 cgtaattaat atgatttccg attagaataa tatgagcatg aggataacgc atacgtattt
    29341 cgtttagaag gtcatatact tgcttagatt taaaaaagta tgatttatga taaaataaac
    29401 ctgacatttg tatttataat ctaagttttt cccactaata atttgagttt ttagaaagta
    29461 tctcttgagg t
//
LOCUS       DAUNLR010000019        28747 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUNLR010000019 DAUNLR010000000
VERSION     DAUNLR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28747
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.019"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            5..793
                     /locus_tag="VLL59_000852"
     CDS             5..793
                     /locus_tag="VLL59_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HER6508990.1"
                     /translation="MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIP
                     RSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYDEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGIYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYNDKFAPFSEGPRIIGEIVGNFMPKEY"
     gene            803..1108
                     /locus_tag="VLL59_000853"
     CDS             803..1108
                     /locus_tag="VLL59_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6508991.1"
                     /translation="MNLENTKLRTKCPSCGKSIILTFHTRRCPKCFLDFKEDYVKRIF
                     YDYESNVANSAFTKVGEKMTSAGEGMEKTGNTIQQIGCIIMLIPIVYILFQLISAFN"
     gene            1232..2371
                     /locus_tag="VLL59_000854"
     CDS             1232..2371
                     /locus_tag="VLL59_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HER6508992.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMKKDTPRIRKEAK
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSIRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMTYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(2454..3494)
                     /gene="rfbB"
                     /locus_tag="VLL59_000855"
     CDS             complement(2454..3494)
                     /gene="rfbB"
                     /locus_tag="VLL59_000855"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HER6508993.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(3738..4331)
                     /locus_tag="VLL59_000856"
     CDS             complement(3738..4331)
                     /locus_tag="VLL59_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HER6508994.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(4331..5200)
                     /gene="rfbA"
                     /locus_tag="VLL59_000857"
     CDS             complement(4331..5200)
                     /gene="rfbA"
                     /locus_tag="VLL59_000857"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HER6508995.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDFPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHELAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(5259..6365)
                     /locus_tag="VLL59_000858"
     CDS             complement(5259..6365)
                     /locus_tag="VLL59_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HER6508996.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KTSGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLMPLGYQVDVRPQKGQ
                     LLDYDVHHIISDNYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKSCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(6405..7193)
                     /locus_tag="VLL59_000859"
     CDS             complement(6405..7193)
                     /locus_tag="VLL59_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HER6508997.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMERDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(7183..7869)
                     /locus_tag="VLL59_000860"
     CDS             complement(7183..7869)
                     /locus_tag="VLL59_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HER6508998.1"
                     /translation="MDSQLSNRLAQVAACVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(7941..8597)
                     /gene="nth"
                     /locus_tag="VLL59_000861"
     CDS             complement(7941..8597)
                     /gene="nth"
                     /locus_tag="VLL59_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HER6508999.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(8594..9277)
                     /locus_tag="VLL59_000862"
     CDS             complement(8594..9277)
                     /locus_tag="VLL59_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HER6509000.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(9358..9876)
                     /locus_tag="VLL59_000863"
     CDS             complement(9358..9876)
                     /locus_tag="VLL59_000863"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HER6509001.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(10026..12236)
                     /gene="recJ"
                     /locus_tag="VLL59_000864"
     CDS             complement(10026..12236)
                     /gene="recJ"
                     /locus_tag="VLL59_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HER6509002.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDLLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(12233..12997)
                     /locus_tag="VLL59_000865"
     CDS             complement(12233..12997)
                     /locus_tag="VLL59_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HER6509003.1"
                     /translation="MGQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(12997..13926)
                     /locus_tag="VLL59_000866"
     CDS             complement(12997..13926)
                     /locus_tag="VLL59_000866"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HER6509004.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(13941..14576)
                     /locus_tag="VLL59_000867"
     CDS             complement(13941..14576)
                     /locus_tag="VLL59_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HER6509005.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(14569..15807)
                     /gene="hflX"
                     /locus_tag="VLL59_000868"
     CDS             complement(14569..15807)
                     /gene="hflX"
                     /locus_tag="VLL59_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HER6509006.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(15880..16779)
                     /gene="miaA"
                     /locus_tag="VLL59_000869"
     CDS             complement(15880..16779)
                     /gene="miaA"
                     /locus_tag="VLL59_000869"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HER6509007.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            16913..17089
                     /locus_tag="VLL59_000870"
     CDS             16913..17089
                     /locus_tag="VLL59_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HER6509008.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(17207..18115)
                     /locus_tag="VLL59_000871"
     CDS             complement(17207..18115)
                     /locus_tag="VLL59_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HER6509009.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFNYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     VSSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQSK"
     gene            complement(18352..18771)
                     /locus_tag="VLL59_000872"
     CDS             complement(18352..18771)
                     /locus_tag="VLL59_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HER6509010.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMI
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDSLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLTAFMAKMVEDSAVQQVLNAAH"
     gene            complement(19082..20068)
                     /locus_tag="VLL59_000873"
     CDS             complement(19082..20068)
                     /locus_tag="VLL59_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HER6509011.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAVKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDENTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVVSKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            20269..20571
                     /locus_tag="VLL59_000874"
     CDS             20269..20571
                     /locus_tag="VLL59_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509012.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(20934..21005)
                     /locus_tag="VLL59_000875"
     tRNA            complement(20934..21005)
                     /locus_tag="VLL59_000875"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20970..20972),aa:Arg,seq:ccg)
     gene            complement(21118..22323)
                     /gene="rpsA"
                     /locus_tag="VLL59_000876"
     CDS             complement(21118..22323)
                     /gene="rpsA"
                     /locus_tag="VLL59_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HER6509013.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKILSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            complement(22450..22521)
                     /locus_tag="VLL59_000877"
     tRNA            complement(22450..22521)
                     /locus_tag="VLL59_000877"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22487..22489),aa:Gln,seq:ttg)
     gene            complement(22573..22653)
                     /locus_tag="VLL59_000878"
     tRNA            complement(22573..22653)
                     /locus_tag="VLL59_000878"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22617..22619),aa:Tyr,seq:gta)
     gene            complement(22714..22944)
                     /locus_tag="VLL59_000879"
     CDS             complement(22714..22944)
                     /locus_tag="VLL59_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HER6509014.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            complement(23008..24075)
                     /locus_tag="VLL59_000880"
     CDS             complement(23008..24075)
                     /locus_tag="VLL59_000880"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HER6509015.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITENNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTSRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            complement(24153..26612)
                     /gene="parC"
                     /locus_tag="VLL59_000881"
     CDS             complement(24153..26612)
                     /gene="parC"
                     /locus_tag="VLL59_000881"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HER6509016.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGIKLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            complement(26703..28652)
                     /gene="parE"
                     /locus_tag="VLL59_000882"
     CDS             complement(26703..28652)
                     /gene="parE"
                     /locus_tag="VLL59_000882"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HER6509017.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAIGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMVDILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKVSYAWTDGEL
                     EDLRREFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
BASE COUNT         8657 a         6186 c         5131 g         8773 t
ORIGIN      
        1 taatatggca agaggacgag ggaaattaac acctcaagac gaggaataca aaaagataat
       61 ttctgctaaa attaacagtt tattgctaga aaacaattta aaacaaggac atttagctga
      121 tgcattggaa attccacgaa gtagttttaa tgaatatgtc aaaggaaatt ccttacctaa
      181 tcctggtaac gttcaaaaga tagctgatta tttcgggtta atgaagtctg atatagatcc
      241 tagatttgca cctcgtaaga aaaatcacga actcaaaatc cctacttctc cacttgtcaa
      301 aaaaataacc acaacagtcg tagaattaaa tgttcctcgt aagcaaaaag ttttagactt
      361 tgcaacagaa caattgaaag agcaaaaaaa taaaattact tcaatagaga aaaaactata
      421 tgaatacaaa gtctatgaga aactttccgc aggtacaggt tatggatatt ttggtgatgg
      481 gaactatgat actgtttttt acgacgaaga attagattac gattttgcct cttgggtttt
      541 tggtgattct atggaaccaa cttatctgaa tggtgaggtt gtgcttataa aacaaactgg
      601 ctttgattat gaaggtggca tctatgccgt agagtgggac ggacaaacct atattaagaa
      661 agtttacaga gaaaaggatg gcttgcgcct tgtgtcttta aataaaaaat acaatgacaa
      721 gtttgctcct tttagtgaag gccctcgtat aataggggaa attgtcggta actttatgcc
      781 taaagagtac tgaggtagat aaatgaattt agaaaataca aaactaagaa caaaatgtcc
      841 gagttgcggc aagtctatta ttcttacttt tcacactaga agatgcccta aatgtttttt
      901 agattttaaa gaagattatg tgaagcgaat tttttatgat tatgaatcaa acgtagcaaa
      961 ttctgctttt acaaaagttg gagaaaaaat gacaagtgca ggcgagggga tggaaaagac
     1021 aggtaacaca atacaacaaa taggttgcat tatcatgctt attcctatag tgtacatttt
     1081 gttccagctt atttcggcgt ttaactaaaa aagccccacg ctctcaaagt ttggcgactc
     1141 tgagcgtgag gcgaatctag tatagtaaaa acctgctttg cagtaggtct ctttactata
     1201 cctattttaa cagaaaatga ggtaaaaaac aatgtggtca gaaaaacaca aaagcggaaa
     1261 agtaaatttt gtagaacggt acaaacaccc gtatactggc aagtggtgca gagcttctgt
     1321 ccttatgaaa aaagacacgc cacgaatacg aaaagaagcc aaaaaatatc ttgacgaaaa
     1381 aatatctaaa atcttaacaa gtcttaccac aaccgatgcc tacctactag atgtcatgaa
     1441 cgaatggtgg gaacatcatc agaaatcact caaatcaact tctatccgct ctcttgattt
     1501 tagaataaga gaattgcgaa acttaattga tccagaagtg atgattgcca agataaccac
     1561 gaaatacctg caaagtatta tcgacaaaat accaggtagt tatgacaaac gtaaacgagc
     1621 acggcagctg ctcaaacaaa ccttcgacta cgctatcgct ttagagtatg tctcaatcaa
     1681 tccagttatt agtacccaac tcgcaaaacc tgttaagacc atcaaagact ttgaagacgt
     1741 tgcccagaag tttttagaaa aagatgaact caaaaggctg ttagatgaaa tgtatagacg
     1801 taaaggatcg attaaaatga cttatctggc agaatttatg agcttaaacg gctgccgcat
     1861 tggagaagct ctagctatac agccagacaa tatcaaaaat gatatcattg aaatccacgg
     1921 aactcttgac tacacctcaa atggctatag aaacgctatc aaaaccaccc ctaaaacaaa
     1981 ttccagttgg cgtgaaacat tgataaccaa acgtgaaaaa gaaattattc aggatatact
     2041 gaaaattaat gctcttgaaa aaaatactaa tcctaattac aaggacatgg gctacatctt
     2101 catttccaga aatggcgttc ctattcaaga caacgccctc aacacctcta tcagagcggc
     2161 aaataagaga ctagaaaaac cgattcaaaa agaactcacc agccacatct tccgtcatac
     2221 cctggtgagt cgccttgcag aaaacaaagt gcccttaaaa actatcatgg atagagttgg
     2281 acatgctgac tcgaaaacta ctcaacaaat ctatacccac gtcacgaaaa gcatgaaaaa
     2341 tgaagtcgtc gacatcttaa atcggctata atatgcccca aaaatgcccc aaaacacaag
     2401 aaaaaacctt gacatcttca acaaacgttg atatgacaag gttctttaat gttttattta
     2461 atcacttctt gagttttagc atacttggct tctacagcat ctttttctgc tttccaccat
     2521 gtctcatttt ctgtatacca cttaatagtt tcttccaaac cttctgaaaa gtttgtaaat
     2581 tgtggttccc agccgagttc ttcacgcaat tttgtagaat caatagcgta acgaagatcg
     2641 tgaccagcac ggtcagttac gtgatcataa gcgtcttttg gttgacccat tttctcaagg
     2701 ataagctcaa gaacttcctt gttgtttttc tcgccgtcgg caccaataag gtatgtttca
     2761 ccgatacgac ccttagtcaa aatagcccat actcctgtag aatgatcatt agtatgaatc
     2821 cagtcacgga catttttccc ttcaccgtat agttttggct tgatgcctga taaaatattg
     2881 gtgatttggc gaggaataaa tttctcaatg tgctggtaag gtccgtagtt attggaacaa
     2941 tttgaaatgg tcgctttcac accgaaggaa cgtacccatg ccttaacgat aaggtcagaa
     3001 gctgccttag ttgatgagta aggtgatgat ggattgtatt ttgtttcagc agtgaatttt
     3061 tcacctggtc cttcaccctg tcctggaagg tcttcacgaa gtggaagatc tccataaact
     3121 tcatcagttg acacgtggtg gaaacggata tcgtatttac gagctgcttc aagcaaagtg
     3181 taagttccga taaagtttgt atggataaat ggacttggat cttccaatga gttatcgttg
     3241 tgactctcag ccgcatagtg aacaatagca tccgttttgg cagccaattt gtctaccaat
     3301 tcagcgtcag cgatatcacc aacaactaac tcaacacgat caccaagaat agcttcaatg
     3361 ttagcacggt tacctgcata tgtcaattta tcaaggacag ttacatgaac atctgggtgg
     3421 ttattgtaga catagtgcac aaagttagat ccgatgaaac cagctccacc agttacgata
     3481 atatttttat acataagata taaagggacc tttcgtttcc gaaaaaatct attaaaagta
     3541 ataactctaa caaagacgtt ttaggcctaa gaaaacatcg ctttctaaga tttgagtccc
     3601 atgttcagct caaagagaga aactgaactt tcctttcatc atttttagtt gttacttgtt
     3661 acctgaagta gagaagaata actcccctca tatccacctc aaatgattaa tcccaatcat
     3721 ctgagtatgt tgtttcccta taggtctttt ggtttcagtg gtttgacatc actaagaaga
     3781 ggatggtttt tatctgcttc agaaacttct gcagctgcta gattttccca agtaatccca
     3841 agacttgggt cagcatagtt tacaaaagca tacttaggtt tcaagtcaag agcccagtag
     3901 tcattgacaa gataactgta agagacagtc tctgaaagaa cttgaaagcc attagcaacc
     3961 cctctaggaa caaacattcc ttttgaagca tcaatcactg tctggtagac gtttccaaaa
     4021 gtctctccct cacgaagatc aacccaagct cctaaaacct tgccatcatc agcaactgag
     4081 atgtatttat cccaaggttc agcatgaagt ccacgcagca catgctgacg tgaaaaagaa
     4141 acgttgtttt gtagttttcc ttcctcaaaa aaacgttctg gaaagccaat tggcaacatt
     4201 ttttcttttt ggaaattttc tttaaaccag ccacgattat ccccacgaac aggaatatca
     4261 aactctagta agcctgggat ttctttgatt tctcggcaag ccaatggttt gtcaaaaaaa
     4321 gtttctgtca ttaagcttct ccaatcaaac gaagcaagta ttgcccgtat tcgtttttct
     4381 ttaaagactg cgccaattca tggacatctt ctttactgat gtaacccatg cgataggcaa
     4441 tttcttccag atttgccact tgagcgtttt gcaaacgttg aactgtttca atatattgag
     4501 ccgcttcaag tagactttca tgcgttccag tgtctagcca tgcaaaacca cgccccatca
     4561 attcaacgga gaggtcacca cgttccaagt aagccttgtt gacgtctgta atttccaact
     4621 caccacgcgc gcttggttta atgtttttag caatttctac cacgtcattg tcatagaaat
     4681 aaagtccagt cactgcaaag tgggacttag gcacttctgg tttttcttcg atagagatag
     4741 cattcatgtt ctcatcaaat tccaccactc caaagcgctc agggtctttc acttgataac
     4801 caaaaacggt ggctcctttt tctttggcag ctgccttttg aagcatttta gtgaggccat
     4861 taccgtggta aatattatct cctaaaataa gagcaacacg gtcatcaccg ataaactcct
     4921 ctccaataat gaaagcttgt gctaaaccat ctgggcttgg ttgttcctta taggataagc
     4981 taatgccaaa ttctgaccca tctcctagca attcttcgaa acgaggaaaa tcttgggggg
     5041 ttgaaatgat taaaatatct ttaatccctg ccaacatcaa ggttgacaat gggtaataaa
     5101 tcattggttt gtcataaatg ggcatcaact gtttagatgc ggcacgggtc agtggataca
     5161 agcgtgtccc tgaacctcct gcaagaataa tacctttcat acgtagtgct cctattcttc
     5221 tatataccct atcattctat cattttttga aagcagtgtc acgctttacc agtagaccgc
     5281 aaaaggtaag gctcagggga atagtcgcta ggcgttaaaa gtccttcgtg tcctagcaat
     5341 aattgagcta attcatagcc aatcaaaggg ccaactgtta atcccgatga ccctaaacca
     5401 ctagctgtat aaaggttctt caatcctgga acctgaccat aaaaaggaga ataatcactg
     5461 gtataagctc ttatccctac acgacatgat ttttgagtag cttcttttaa taacggcaaa
     5521 taagtgagag cttgcatttc aagtttttct aagacctgcc aatcaggctc caaatcataa
     5581 cctttatcat tttcatggct cgcaccaaca gaaatcttac cttgattgaa aggaatgagg
     5641 tctatttcac cttctggcat aacaacggga taattgtcgc tgatgatgtg atgaacgtca
     5701 taatccaaga gttgtccctt ttgtggtcgc acatcaacct gatagcctaa aggcatcaat
     5761 aagtcaggta gccatgctcc tgctgccaga atgacctgat caaaataatg accagcaatc
     5821 tcataaccac ttccttgctg tttcagagtg actttttggc gaataactgg ataaccacta
     5881 gtcttgagta acgtctcaca taaagcggct ccctccactc tagcagctcc tgaagcgtac
     5941 agacagttat caaagccaat caatccttta aaatcattcc ccagttcttt acgattttta
     6001 atggctaact caccaataat cggtgattct acctttcttg ctaacgctaa ttcataaaga
     6061 tctcttagtt tttcttcctg cttttttaaa acatagatgc cattttgctg ataaaaatct
     6121 gttgcaaaac catcttcttt gaggtcattg attaattgct gataaaagtc cgctcctaaa
     6181 cgagccatgc ggtaccaaac tttattgcga cgctttgaaa accaaggact aataatacca
     6241 gcagcagcct tagtggcttg tccttgacca tggtcaaaaa tggtaacttc tttttgacca
     6301 ctttgttgta aataataagc ggcggttgat cctacaatcc ccgccccaat aatggctatt
     6361 ttcattcctg gtatcctttt atcttacttt aagaccttaa cagcctataa atggctaaat
     6421 ggattggtcg aggctttgct tgaaataatg ctgacatccc aaccgttctc ttctttccac
     6481 ccttggagtt tctcctttaa tttctccgta aaaagcacct caatatgatg ccccgggtca
     6541 accgcaaata gtccttctgt cagcatctcc tgtgctgtat ggtaatagat atcccctgta
     6601 atataaacgt ctgcgccttt ttgcacagca tcctgataaa attcaccacc acttccgcca
     6661 cagatagcaa tctttgaaat caaagggttt tccttatcgt aacggataag tcgcacggta
     6721 tctaaatcaa acaccctttt gaccttactt gctaactctt ctaacgcttg ttctttaact
     6781 gttccaatac gaccaatgcc aaagccttct ttggtttcag acaagtaagt tgcttccttg
     6841 atttctagca ggtcacaaaa ccaatcattt agcccgcctg gtacaatgtc aatattggta
     6901 tggctcacat agacagaaat gtcatgcttg accaaatcta gaaggatatc acgctgaggg
     6961 gatgaaacca gatctttaag cggtttaaag atgggagcat gcttagttat aatgagatca
     7021 acttcatttt tgatggcttc tgctactgtt gactctcgga tatctaaagt aatcataacc
     7081 ttacgaatgt ctttatccaa tgaacccatt tgaagacctt taacgtctct ttccatagat
     7141 aaatcaagtg ggcaaaaggc ttcataggca tcaattaggg ttttagcttt catgaacaat
     7201 cacctctttt atttgttgta tttttgtcaa gagaagctga cgctcttgag ttttttcttc
     7261 tgggatgcag gacaaggcat aagctaactt atccatttct cgttgccact tctctttaaa
     7321 aacgactgat ttttcctgag aaaggtatgg accaaaacgc aattctgtcg cggataaggc
     7381 cttttcacca tgctcagcaa cgatgatttc ataatatttg tcattttcag ccatgatggt
     7441 ttctgcaaca attttaaaag cgttaaccga taaccaagcc cgtaaatcat cctcacgatt
     7501 gttgggctgt aaaaccagac gttcaatgcc ctgcaatttt tccttacctg cctctaaaat
     7561 atcagcaatc aaacggccac ccatgccaca aatggtaatg gctgtcacat catcagcttc
     7621 ttcaaaggct gcaaggccat tggctaagcg cacctgaata tgctcggcaa ggccagactg
     7681 tgtgacattt ttaagagcag attcgtaggg acccctaacc acttcgccag caatggctgc
     7741 tgaaatctga ttagtttcta ccaaaaatat gggaagatag gcatgatcac tgccaacatc
     7801 taataatttg acaccttttg gaacacaggc cgcaacttgg gctaaacggt ttgataattg
     7861 actatccatc ttgatttctt tctaaaacgt aatggttcta ttatagcaaa attacctcca
     7921 taaaaaaaga aaaccaaagg ctaggctttc gattttccat aagtattttg atagtactta
     7981 cagtaagact gaacgggaca aatctcacat tttggttttt tggctaaaca atggtagcgt
     8041 ccaaagaaaa tcaatcgatg gtgagtaata atccaatctt tctttggaat tttagccatc
     8101 aaatctgctt caatctgctt gacatcggca tctggtgatg aaatattgag cctctttgag
     8161 actctagcca catgagtatc aaccgcaata gctggaacac cataaacctc tgccaatacc
     8221 acattggctg tttttcggcc aacacccggt aaactttcaa gctctttgtg ggtttttggc
     8281 acttgaccct taaaatcatc acgaatagcc tgagcagttt taatgatatt tttggcctta
     8341 tttttataga gtccaatcgt tctcagagca ttttcaacat cagaaagttc agcaaaagct
     8401 aagtcttcta tttctggata agactgccat agtccaggag ttaccttatt gacggcctta
     8461 tctgtcgttt gagctgataa aatcaccgca attaacaatt gaaaaggtgt ttcccagtct
     8521 aactctccct tagcctcagg aaacatttga ccaatgatgg tcaggacttt tgctaatctt
     8581 gcttttccaa ttctcatgaa tcactccata aattcatcgc agatagaaaa tcctctgata
     8641 tcgtcacttg agaaagatct tcgccttctc taacacgtct acgttcttct acttgtcgaa
     8701 gattaacaat accttctttt cgccaattac gtaagatagc ctggatatat ttccaatttg
     8761 ttttgccgtt gaagacagct tcttttaaag cttctcgtat caaatcagga tctgttttat
     8821 catcacgaag cgttttttca agatcttcta actcaaaagg actcaagaat cgtcctagtt
     8881 cacgttcaaa ttcatcaact aatcgtttga aatgatttgg tgtttcttgt ttgtcaattt
     8941 cagttgccgt ttgactgaca aacaattgat ctaacttggc taacacagga ctcgcatcaa
     9001 aaataatttc aatttctcca gtaagttcaa ttgtccgcat atctaaaagc ccttgactag
     9061 tcaaagatga aatgatttta ttaatatcag caactgattt tccaagcgca tgagcaattt
     9121 gactgggtgc taagtcgtct cgctttgtcg tattttgaag atagaaaaac tgccagacca
     9181 aaaaatcatc tgagctctta aaaagatctt tgtaatgaaa aagcaaggca cttgggataa
     9241 ccaaattacc cgacttataa tgttctaaaa aactcataat ccctcaatca aaaggctaaa
     9301 atcgaatcta tagcctttac tactttaaat cccctaatca gatgctgatt aatgtgctta
     9361 cccaggaaac tgcattaaga ctttatagtc atagttccta atagcatggc gaccatttaa
     9421 accttctaat tcaataagga aggcacaacc agctacaata ccaccaagtt tttcaatcat
     9481 ttcaatagtt gcttttaccg taccgccagt cgctagtaaa tcatcgacaa tcaaaacacg
     9541 ttgtccaggc ttaatagcat ctgcatgcat agttaaggta tcaagaccat attctttttc
     9601 gtaatcagca gagacaacat ctcttggcag ttttcctggt ttacgaacgg gagcaaaacc
     9661 aattcctaac tcaactgcaa caggacaacc aatgataaaa ccacgcgctt caggtccaac
     9721 aaccatatca atatctttat cacaagcgta ctgtgctatt tcacgaatag catagctata
     9781 tgctttaccg tcagccatta aaggtgagat atctcgaaac gtaataccag ctttagggta
     9841 atctttgatc gatgcaatgt aatttgttaa atccatagtt aattctttct agtggcaaat
     9901 tgccaaatat aaaatactct tcattatatc acgaaacata tttttcgtaa aataagactt
     9961 ctgacattat gtttatctga tacttcattc gtaactacct caataactac tgtcaactgc
    10021 tttacttatt gatcgtttga tttcaccaaa taatcataca tctctttcgg gctagccaaa
    10081 gccatgattt cttgaaattt caccaattct tttaagtctt ggtaaatgtg gctctctgaa
    10141 atctctcgtt tttgcgcttg ggggttaacc gtcatcagcc catcgtcaat cgtcacaaaa
    10201 gacaactctt caaaaatttg aatcaactta atcagtaaaa gtttttctat gtttaaatag
    10261 tgactcaact ctgtcaattt atgtcgtaaa tcaaattcag gaaactgata gatggttttg
    10321 tagagcttgg caaactgctc tctgctgcca aatcctgtta aataataagg atgtttcatc
    10381 tgatttttaa aatagatggc gtcaaaatcc ttgtgaacaa actggttgcg ccaggttttg
    10441 aaatcttcag ggatgtcatt aatcagaatg actctggcat ttgggtcttc ttcaatagtc
    10501 ggaatacctt caggaacttt ggctgttttt gtccttaagt caagaagttg cactccgtca
    10561 acacgagcat ctactaacat gaattggaga ctcgtgttcc cattccaatg gttgacagat
    10621 aaggtaactg ctaattctaa accagtagct tgtcggaact cttgcagttg acttccttga
    10681 ccaaaagcca gtacgtcaaa ggaagctttg ccctgactga ctttaaattt aagatggctc
    10741 tggtcttgcc ctatggtacg cgcttgacta acccttatgt ccttgacata aaagaccggc
    10801 ttttgatgat ccatcccata aggggctaat ttatctaaac tctttaaaat atcaaggcta
    10861 aggtcgtcca aagacagtct ttcatcaata gttaacgtat ttttggcagt ctgatctaag
    10921 ccacgttcta tcacaaactg acagagcaag tctgagagag cttccaaatt gtcaacgggc
    10981 agggtcattc ctgctgcacc agcatgtccc ccaaaggctg taaataactc acgcttgcca
    11041 ttcaaggctt caaaaatatt aatagcttct aaacttctgg ccgagccttt tgcaaagcca
    11101 ttatcaatgg tcaaaacgac gaccgtttgt ccaatagttt ccatgatacg accagcgaca
    11161 atcccaagaa caccaggatg ccagccagct tgtgccaaga cttgaacagg tttttgagga
    11221 tcaaccatag ccatcgcttg atcaaaaatg tcttggacta aggccttacg ctcttcattt
    11281 tttttcttaa tcatcaaggc aatcgcttga gcttcttggt catcaaagcc cgtcagtagc
    11341 tcaatggctg gattagggtc atctaagcgc cctaaagcat ttaattgcgg agcaatctga
    11401 aagccaatgg cgtcttcatt aaaatgttcc aaatcaatag gagacaagga catcaactcc
    11461 tgcaagccca ctctttcggt gtgtttgagc atggccagac catttttgac taaaacacgg
    11521 ttttcacctg tcaagcttac catatcggca atggttccaa tagctaccaa gtctagacag
    11581 tctgttggta aactttctag caaagctgtt gccaatttaa aggcaacgcc acagccagct
    11641 aagtgtttaa agggataatc agcatcagga tgctcaggat gaatgatggc aaaggcttct
    11701 ggcaattctt caggcaggct atgatggtca gttacaatga catcaacttc ctgttcttga
    11761 gcatatctaa tcgcttcatg tccggccacg ccattatcaa ccgtgataat tagggacaca
    11821 gcttcctgct caataaaata tttatagacg ctctggttgg ggccatagcc atctgtaaag
    11881 cggttgggaa gataaaccaa aggctctgct cccatcatgt ctagggtttc tttgacaata
    11941 gaagccgacg tcatgccatc agcatcatag tcgccgtaaa tgagaattcg ttcgccctct
    12001 tcaatagctt gacgaattct tggcacagct tttgccatgt catgtagcaa gtaaggatca
    12061 tgcagttgag acaagtccgc tgttaaaaac tcatctaagg cttcttcagt ccttatccct
    12121 cgatcataaa tcaactgagc ggcggtctgg gttagacctt ttgtctttgc tagcttaaag
    12181 aagccatcat ctggcttctt gtcttttatt ttccagctat atttggattt aatcatttat
    12241 aattaaatac ctttcttgca agataatcag ataatttagg gaaaagggtg taaaattgat
    12301 gggtcaccgc taaactaaag ggcaaattca attctcgttt atttttcccg ataatagaaa
    12361 ccaaacgctt agccacttga tttggttgga gagtaaattt accaacgctt tccaaataat
    12421 gtccagacgg gtcagcttgg tcaaaaaact tggtggcaat gggacctgga ttcacggtgg
    12481 tcacataaac ccctttatcc gctaattcta agcgaagggc attggaaaat ccgataaggg
    12541 caaacttggt ggctgaataa atgctcgatt tggctgacgc aatcaagcct gccatggaca
    12601 caatgttaat aagatgacct tgcccctgct ctgccatttt ctgaccaatc aagcaagcaa
    12661 agtgaatgct cgctagggtg ttaacctgaa acatatcagc tatttcttgg gcagaaaact
    12721 cttcaaagcc tttgaaagct ccatagccag cattattaat caagacatca atacggccat
    12781 agcgctggta aatctgggcg accattttct caatggctac tggattggta atatccaact
    12841 caaggcattc tttgttgtca atatgctgat aacagtgttc taggcgttct ttgttacgtc
    12901 ctaataaaat caagctgtct tccttgggta actgcttaac aattgcctga gccagtcctc
    12961 cagaagctcc cgtgataaca atgattcttt gtcccattaa ataatcactt cctctaaatc
    13021 ttgtaccatt ttaacatttt caaatatagt ggcggcatct ttttccatct ggcgacaatc
    13081 acgccctaaa aagcgagctg atacatgatt gagcaagagg cgttttgcgc ctgcttcatg
    13141 agcgatttgt gctgcctgca tgttggtaga atgcccgtga tttctcgcaa tccgctcgtc
    13201 acccttacca taggtggatt catgaaccaa aacatctgca tctttagcga gtttaacact
    13261 ggcagacgtt ttgcgcgtat cgccgataat ggtgatgatt ttgccttttt taggggcaga
    13321 aatataatct ttggcacaaa tcaggcggcc gtcttccaac tcaacgtctt gaccattttt
    13381 aattttgcca aagagtggtc caaagggaac acccgctgct tttaaggctt ctgcgtctag
    13441 ggttccttct aagtcttttt gaactactcg ataacccatg caaaaaatgg tatgcgccag
    13501 acgctctgca tagacctcaa acttatctgt ttccattatt ttacctaatg atttgtcatc
    13561 aaattcatga aaatgaatct gataaggtac acgcgctcca gaaactttta gactagttaa
    13621 cacgtaagtt ttaatgccaa ttggtccata aatatcaaga tctgtctgtt cttcactagc
    13681 ttgaaaagac cgacttgata aaaatcctgg taatccaaaa atgtggtctc catgcaaatg
    13741 agtaatgaaa atctttctta tttttcgtgg cttaatcgtc gtttctaaaa tttgtctttg
    13801 cgttccttca ccgcaatcaa acatccagac ttcattgatt tcgtctagta atttcaaggc
    13861 aagacttgac acattgcgct gcttggctgg ttgaccagct ccagttccta aaaattgtaa
    13921 ttccattcaa tctattcttt ctattgggtg atgtaaatca taaattctcg ttgggcaaaa
    13981 tcataatact tttgaccaga aaatgtttgg ctaagagccc ataactcctc tacattaaac
    14041 cccttaagca tggtgatacc gtttgccaga cggtaaatct tcgacaagag tgtgtcatca
    14101 ggtgtaatgt cttcacattc tccttgctca aactgcttag cctgcatttt aagctggcct
    14161 ttgtcctcat aaaccatata ttgtgggaaa atttgtgtta attcaaagaa gagttcgggt
    14221 ttcttaggct ctgctttttc agaaaatacc aatgcaactt cttggtcatt ttggtaagca
    14281 aaaccataag cttttccaga caaattgagg cgtacaaagg gcttttcttc ctcaaaagat
    14341 ggttggtcag taaaaagccc caaagcctta gaaagattaa aataataatc agttgcagct
    14401 tgcggtgact gtttctggta gatttcagca aagtaggcat taataacact tggtggtggt
    14461 gtgataaaag ctagtttttg ctggtctgtc aaactggcta acagatggtt taggtagttg
    14521 gtatccagac tagtaaatcc accataggtt tttgctaaat caatataatt attcataaaa
    14581 atcgtcaagt ctccattgct gttttgggga aatgtagccc gaaatatcct ctatttcttg
    14641 gtcaaacgtg tagtggtcta aaagagcaac tcggttcaaa tcatatagct tgtacgcctt
    14701 gtcttgatgc actttgattc taaaaggaac aaactggtct cgaatttggt caatgattaa
    14761 acgtctcaag agaattttgc tatcctttga acgggctgaa atcctgatat ttggaaaagc
    14821 agtagctgtg aattgttctg ctatatccac cttgttataa atagctaaac gcggaatatt
    14881 aagcatgtct agctctttta gaaggtttaa aaccactttt tcttgctcac tatgattggg
    14941 atcactcgca tcaatcacat gtaacagcaa atccacatat ttgctttctt ctagggttga
    15001 tttaaaagca gccactaatt ccgttggcaa gtcttgaata aagcctacgg tgtctgttaa
    15061 ggttgcttga aattgatttt ctaaatagag ttgctttgta gttgcatcta aggtagcaaa
    15121 taattcattg gcttcatagt ggctgtcatc tgtcaacaag ttcataatgg ttgacttgcc
    15181 agcattggtg tagccaatca agccaatttt aaaggtatct gaacccacac gacgatctct
    15241 aattgtttga cgatttttct ctacctgagt taattggcgt tcaatatcag caatctgatg
    15301 acgaatcgaa cggcgattta actctagttg gctttcacct ggtccacggc tcccaatacc
    15361 acctgcttga cgacttaaca tgatgccctg tccaaccaaa cgaggtaaca tatatttcaa
    15421 ttgggcaagg tgtacttgta atttgccctc atggcttctg gcacgcatgg caaaaatatc
    15481 taagattaac tgcatacggt caatgacttt tacctctaaa acagcttcta gattagcatt
    15541 ttgcctagca gtcaaccgat tgttcacaat aactgcatca atctcatcag cttccacaat
    15601 cgccttaatc tcatccagtt tccctgagcc gataaaggtt ttgctgtcgt aacgttctcg
    15661 tttttggctg aaacttgcca taactttgac gccagctgtt ttggcaagat tagctaattc
    15721 tgtcatggac atatcaaaat gttctgttgt ctgaagctca actcctaaaa gaatcactct
    15781 ttcttgctga cgctttgtct caatcatcac ctttaccaat cctccaaatt ccgtaaattc
    15841 tattataaca tatcttcaac agattctgct aattttgcgt catgacttct ctttctgacc
    15901 aagaaaatcc ctgaccctat catgtactac ctgtgggtaa tcaggagccg ttatggcagt
    15961 gaagctaaca gccattcgat tgcggaacca agtcagctgt cgcttggcaa aacgtctcgt
    16021 gttttgtttt aattgatcac tagcttctgc caaagtcatt tcacctacaa aataggggaa
    16081 taattcctta taacctatgc cacgactagc ctgaacagtc gggtaatgct catataacca
    16141 ttttgcttct tccaataagc cgttttcaag catacgattc acgcgctgat tgatacggtc
    16201 atagatgact tggcggtcat cattcaagcc gataataagc ggctcataag ccgtctcggc
    16261 attctctaat tcatcagcaa actgagccaa ttcaagggct cggatcgccc gtctgcgatt
    16321 cacctgctca atggtaatgt tattgacttg caagcgttca tacaagtcgt gatcgtccaa
    16381 ttgctccaac tcatttcgat aggcttttac cgcctcttga tcaacttgac ctcctagatg
    16441 ataaccttcg agtaaacttt gtaagtaaag accagttcca cctacaataa ttggtaattt
    16501 cccacgacta acaatgtctg aaatagcttt ttgagcatct tgaacaaaat cgtaggccga
    16561 ataagactcc gtcacctcac gaatatcaat taagtgatga accgctgctt cttgctcttc
    16621 ttgagtggcc ttggctgttc caatatccaa ctgtcgataa acttgctggc tatctcctga
    16681 aataatttct ccattaaaag ccttggctaa actaatccca agtgctgttt ttccaaccgc
    16741 tgtcggacca acaatcacaa ctatttttat ttttgtcatt ttcttgtctt tctattagaa
    16801 aagcgtgttc aaaaacgcct tttacttgaa aattagctta tttttcgcta ccatatatta
    16861 taacataaga ttaaggacca ctgaggtcct tcactagaaa tggagaataa tcatggttaa
    16921 gaaatatcaa tttgttaaag gtcttgctac tggcgtccta gcaactgctg ctactgttgc
    16981 tggtgctgtc tttgctgtaa aaaaaacaat cattgaccct gaagaagaaa aagctgcttt
    17041 cattgaagaa aaccgcaaaa aagctgcgcg tcgtcgtgta gctcgctaac gtgacaatgg
    17101 atcaatttaa aagagactag cacattaaag tgccggcctc ttttttagta atctcgataa
    17161 ctagttagta gtaactgtct cttgatgagc caagatgtta gctgctttac ttactttgaa
    17221 atagaaatct caggtaagcc ccataaacat acgtgactaa agctgtcgcc aacaatacct
    17281 ctcctagcaa aagaacctgc caacctaaac cttgccaacc taaaaaagat aaggtcattt
    17341 ttaaggaagt ggcactaatc acaaacggaa aggtaaaagc tgaaaaacct gggttaaagg
    17401 gacgattgag taagcgagga agctgtacaa ccacaaaagc atataacagt tgtgagctga
    17461 cgagaagaaa gataaccatt cctacttgtg gtctaggaaa ggttgctaaa taagacgctg
    17521 aaagtaagga cagaggggca caaaacgttg aaatattggg cattactgct tgacctagac
    17581 caatcccata agtctttttg gccataaaag gtaaaatcac agcagttagg agaagacaaa
    17641 cccaaaaaat cacctgtcct aataaaaact gcctactagc aggtgctgtt aatgccgcca
    17701 ttgcaattcc aacaaaaagc acggaccagg aaggaaaaac gttatcccat gaaaaagaaa
    17761 agacaaaacg atactggtaa taagcaatca ggacaagatt tcccaaaaag aatagccacc
    17821 aagtgagaaa gcctaaccaa caccctcctg tcactttgag aaagagtgaa gacaacaaca
    17881 tccctgtcat aaaaaaagtt ggaaaaacag aggcaattag aggttgtcgt aactgcattt
    17941 tggtatcgtt aaggttccta accatgccaa caagcaagat accatagata aaaagagctg
    18001 ccagaattcc caaataatta aaaatcgaaa cataagtagc caacaaattg ccaaatgaca
    18061 acgttcctaa tgccaatcct gacatgacca atggtgggtt tttaaggtgt ttcataagtg
    18121 tccttttctg cctattaaca gctattttta gtgacataat cttgtttatt ttatcacatt
    18181 tcaagcattt ttgacaccac ccgcgaaaga aaatttaagg ctcttgccat tgttttttta
    18241 cattctcgca aaactaggaa actgctcaaa aagctaagga gtgaccactc ttctctagaa
    18301 aaatgaaaga gtagagaaga cttggtctga tctttacttc ttctttttga tttagtgagc
    18361 tgcattaagc acttgttgaa cagctgaatc ttccaccatt tttgccataa aagctgtcag
    18421 atgcggataa ttctcgtaag attttggtgt tttttgagac catagcgcca tggcgtaagc
    18481 ataagcatct gcaatggttt gttgatctcg ataaacatgc ccactctccc caataagact
    18541 atctaaatgc gtcatagcaa tatccatccg cttgtaagaa gcttgtttga ctttttcaag
    18601 cgcttgattg tcttgagaaa tagtgtagcg atgagggttg atcattggcc taaaaacaag
    18661 gggaaaatca cctgttaaga agtccatgat ttcgttgaac cgactttctg ccaaaagatt
    18721 atcttgggga atgagctgag atttcagggt ttgtttcgct ataaagggca agataatacc
    18781 tgcctgtgtg acaatttgac catcatcaag ctgtaaagct taaaccattc ccaaaggatt
    18841 gatggtaagg cagtcttcag aatccagttt taccttctct atctcgtaat acagaaactc
    18901 acaattcttt tgaaaaggtt ctagacagag ttggtgttga cgtcttcgct gttgatggct
    18961 ctgcatgaca aaatgagctt ggtgtccacg ttcactggta tcttgttgca aagtctttgc
    19021 aatttggtct catcatctgt atcacaaaaa acaaaccagt ttcctgattt gttttgagat
    19081 attaggcacc tacaaattct ggcaaggatt ctccaatagc ttctaaacgt tctgcccatt
    19141 cttgacgtga taaaccattt tcttgcacat agcgattacg ttcatgtgca cgacattcag
    19201 gcgagcatcc tcgaacatac tttgtttcgt tttcttctga agcaaaaatt tgtttgttac
    19261 aaaacggatt tgcacaattg acataacgtt cacaaggtgt tccatcaaaa taatctttac
    19321 taacgacagt tggattaaca tgattaattg gcaccgagat acgatcatca aaaacataca
    19381 tcgcaccatc ccaaagttca ccttgaactt ccggatcttt tccatatgtt gcaataccac
    19441 cgtgtaattg tccaacatct ttaaagcctt ctcgaaccat ccaacccgag aatttctcac
    19501 agcgaacacc accggtacag tacacgacaa cacgtttttc cataaactta tctttgttgt
    19561 cacgtaccca ttgtggtaac tcacggaaat tgcgaatatc aggacgaatt gctccacgga
    19621 agtgacctaa gtcatactca taatcattac gcgtatctaa aacaacagta ttttcatcaa
    19681 gcaaggcttc tttaaattgt ttaggattta aatactcacc tgttgtttcc aaaggattaa
    19741 tatcactatc aaagttattg tcttctaacc caaggtgcac gatctctttc ttataacgaa
    19801 caaacatttt acggaaagct tgttgatttt cctcgtcaat cttgaaccaa agatcagcaa
    19861 aacgctcatc gctgtggacc caatccatat acttctgagt tgtttcataa tctccagaaa
    19921 cagttccatt aatcccctca tccgcaatca aaatacgacc tttaagccca atagatttac
    19981 aaaattctag atgtttcaca gcgtactctt gcgcattttc aattgaaaca tatttataat
    20041 agagtaaaac tctgattttt tctgacattt tttctccttc attgttattc agttacttcc
    20101 tattatatct aggaaaaaca agtctaggca agccatttgt ttgtcttttt tttcacaaaa
    20161 tagatctcaa tttatttttg atgagatgag atggcaaccc attactcctt taagcaaatc
    20221 attagaagct ttatttagaa aatgctaaga taaaacaagg aggccaaaat gacttatgaa
    20281 ctttgtttag aatatgggac ttatccgttg tcacgtgttg atgcttactg gggagaagat
    20341 caaaatcccc caacattcat tcaagaagat cgactgcttt gccataaact agaaactatg
    20401 aatcacctgt tccatgattt atttgtaact attgaatcac aattccatta tgttggtttt
    20461 aacatgcctg aaaaaagagc gcagattcgg atactatatc aagaagtagc tactatatta
    20521 aaatccaaat ataaggatta tccaattaag attgagacgt ttcttcttta aaaatctaat
    20581 actaaaaaac taactgtgct tagatagatg acacagctag ttttttaggt aaaactcttc
    20641 ttaaatttta aaacgtttcg aaaaatcact aaatgcttta atagcacttg ctaaaaatgg
    20701 tttcaccatc tcatcattaa ttaaccttga ttacttacaa tcttatgaat ctgagtcaaa
    20761 taaaattcag gctgtggcat tacagagaca tttaaaacct atactcatcg ttttcaaggt
    20821 cagaaagaga atgattttga aaaggttcgt caactcttct agataatttt ggacaaattt
    20881 tgatcaagaa acaaaaagag cctatcaaat aaggcttttt tatatgattt ctatccacct
    20941 tgagggaatc gaacccccat ctcaagaacc ggaatcttac gtgatatcca ttacactaaa
    21001 ggtggtcaca actttgtcaa tacccttata gtatatcata aaatgaaata atatgaaata
    21061 acttttctaa ccagaagaca ataaaaagtt gaggaaaacc tcaacttttt agatttatta
    21121 caattcaata tcaccgaaaa gatcagccat tgagaatcca gtttgtgttt ctgggagttc
    21181 gtagtcacgt cttgattcac gttttggacg acgtgggcgt gattgacgtt tttcttcttt
    21241 gttgtctcct tcagcttgcg ctgggcgttc ttcaagagct ttgattgata atgatacgcg
    21301 ctcatcagct gcattcactt caagaacttt aactgttact tcttgtccta cagaaagtac
    21361 atcttttgga ttttcaacac gtttgtgtga aatttgtgaa atatgaacaa gtccatcaat
    21421 acctggtaat acttcaacaa aagcaccgaa gtcagtcaag cgttttactt taccttcaac
    21481 aacatcacct tgagcaagtt tttgttcaac gccgtcccat ggtccaggtg ttgttgcttt
    21541 aagtgaaagt gacacacgac cagcttcttc gtcaattgaa agaattttaa cttcaacttc
    21601 ttcaccaact gaaacaactg atttaggtga cacgttacgt tcgtgagaca attcagtcac
    21661 gtgaacaagt ccgtcaacac caccaaggtc aatgaaagca ccaaaacttg ttaaacgcgc
    21721 tacagtacct gtaacgactg caccttctga aatcttagag aacacttcag cacgagcttc
    21781 tttagcggcc tcttcgataa cttcacgacg tgataggatg aaacggtttt ctgctgcatc
    21841 aacttctttg attttagcat caaactcttg tccaacaaat ttttcagtgt tgcgaacaaa
    21901 acgagtgtca atcattgaag cagggataaa tccacgaagt ccttcaaatt caactgaaag
    21961 gccaccttta acagcacgcg tacctttaac agtaacaact tcgccttcac gaccaacaag
    22021 tttgtcccag gctttacgag cttccaaacg ttttttagat actaggaaag taactgtatc
    22081 agtatcttta cctactactt gacgaagaac aagtacttca actgtgtcgc cagctttaac
    22141 aaagtcgtta atatcagcat cgcggtcgtt agtcaattca cgaagtgtca agacaccttc
    22201 aacacctgtt ccttcgataa caacgtttgc ttgaccgtta tcaacagtta aaacttccgc
    22261 agtgacaaca tcaccagggt tcacttcgct aacactgttt agcaaatctt caaattcatt
    22321 cattctaaaa aatcctccaa caaaagctag ccaatgctag cttttgataa caatatattt
    22381 tctcaaggta acccgcaacg acaacaactc ttatctttga cggtctcagg gagcacctga
    22441 tacctctgac tggggtagct ggattcgaac caacgcatga gggagtcaaa gtcccttgcc
    22501 ttaccgcttg gctatacccc aaaaatattt ttttacagaa aactaatttt ctaattagat
    22561 tagtttccga aatggaaaga gagggattcg aacccccgaa cccgaaggag cggatttaca
    22621 gtccgccgcg tttagcctct tcgctatctt tccgtaacaa caaaaactat tctatcatag
    22681 tttttgtaag ctggcaagtg tttttgtcta attttaatgg ttcaaattgt agttttcaat
    22741 gatattttca accgcttgtt cgagcgtttt gaagaagcaa tctactccat cattttttaa
    22801 gacagcaaat ttctcatcaa gttctgcaat ttctccaacc acacgtttac caatttgtaa
    22861 ttgatagcca tcaatcttag tctcattaac cataactttg tgatcaatca gttggatttc
    22921 aattttttta tcttttttac tcatcacttt acctcacttt gtctatttta cacaaaatca
    22981 aaaaagcttg caagagcaag ctctatttta atctactttt acaatccaac cttctggtgc
    23041 ttcaatatcc ccaaattgaa tgccgaccaa ctcatcgtat aaacggcttg tcacaggacc
    23101 aacttctgtt tcactgtaaa agacatgtaa gttatccttg tactgaatac cgccaattgg
    23161 agagataaca gctgctgttc cacaagctcc tgcttccaca aatttatcca attcattaat
    23221 tggaacatca ccctcaatta ctgtcatacc aagtctttct tcagctagtt gtaagagtga
    23281 atacttcgta atagatggca agatagatgg actaagtggc gtaacaaatt cattattttc
    23341 agtaatgcca aaaaagtttg cagctccgac ttcttcaatt ttagtatggg ttgctggatc
    23401 taagtaaatc acatcagaaa agcctgctga tttagcggcc ttacctggta gcaaacttcc
    23461 tgcatagttt cctcccacct tagcagcacc tgttccgtaa ggagcggcgc ggtcaaacgc
    23521 ttcagaaaca ataaaattag ttggagcaag tccacctttg aaatagtttc ctactggcat
    23581 ggcaaaaatg gtgaaaatat attcttcggc tggtttaacc ccaataatat ctccaactcc
    23641 aattaataac ggtctcaggt aaagcgttgc acctgttccg taaggtggta caaagtcttc
    23701 attggcttta accacttgct tagctgcatc aataaattgc tctgttgata cttgtggcat
    23761 caacaagcgg tctgctgtgg cttgtaaacg cactgcatta cggtctggtc taaatagttg
    23821 aatagagcca tctttggtgc gataagcctt taagccttca aaagcttgtt gtccataatg
    23881 aagcgctgga gcgctttctg agatgtgtaa ggtggcatct tctgttaatt gacctttatc
    23941 ccattgacca tttttgtaat aagaaatgta acgaaatggc aacttatgat attcaaatcc
    24001 taggttgtcc caatcaattg ctattgtcat catcgtacct cttttctgct tttttctatt
    24061 gtaacttttt ttcaataatt ttcaagttta ttctactctt ttgcattaat attctaaatt
    24121 taccataaaa ttaaaaagag ttttcactct ttttaacgtg ttctagctac cagtacttct
    24181 tgatccgaaa tagtgtctga aataaaggag ccattgctgg ttctttccga taacgaaagc
    24241 gtttctaaag caatctcgta ggtttgacca gtcttactaa tgacttcaag catttgttga
    24301 ttagtttctt cttcaggtat atcagtgaac aaatcaaact gctcagctga agtatctgat
    24361 tgaacgcctc cggccagaaa aactctatga ggtttggttt ttaactctcg taggaccaat
    24421 agtccacgat tggcacgact tgtctgagga atatcatcga cagccatccg tttgagagaa
    24481 cccctctgag ttaagacaaa gaaagagtta cttgtcacag caaaggctga ggcaaggctg
    24541 tcatcatttt tcaatttaat gcctttaaca ccagcagatt tcaacccttg aataggcact
    24601 tcctgactgg agaatcgcaa agcataacca tttttagtca ctaataggag gtcttccata
    24661 ataactggtg acaaggtaac cacgcggtct ttgtcatcct ttagcttcac atatttggtt
    24721 gatttagatt tataagttcg ccaaggactt agttctttac gatcaaagcg tttgataaaa
    24781 ccattttgtg tgacagccac atacaagccc tggtcaaagg aagtcacaat atcagcgtag
    24841 agaatctctt cttctgtcgc gaagtttgaa atggtttgtg ataaatgttc accgatatcc
    24901 ttccaacgta aatcggtcaa ttcatggatt ggccggtaaa tgacattgcc taaagttgta
    24961 aacaacaaaa ggtgttctgt tgttttggcc tgtttaacga agatgagttc gtcatcatct
    25021 ctcttgccaa cttcttccaa actagacgca ttgaaggatc gtgggctggt tcttttgagg
    25081 tatccgcccc gtgtcacact aacaaaagtt tcttcctctg caatcaagct ggcagtgtca
    25141 atctcaatga tttgactttc tgcttgtaac tctgataaac gaggattggc gaatttcttt
    25201 ttcacttctc ttaattcacg tttcatgacg ttatacatgg ttgcttcgtc accgataata
    25261 gcggaaaggg tcgtgattaa gtctcttaaa tcattttctt cattttggag agtaacaata
    25321 tcggtattag ttaaacgata aagctgcaag gttacaatcg cttctgcttg ttcctcagag
    25381 aaatcatagc tgactttcag attttcttta gcatcagcct tattgtcaga cgatctaatc
    25441 aaagcaataa tctcatctaa gatggacaag acacgaatca atccttcaac aatgtggagg
    25501 cgtttttcag ctttggcttt atcgaattta gaccgctcaa taataatatc tttgcggtga
    25561 ctgatatagc ttgatagtat tttttgaagc cctacttgac gtggtgtgaa gtgatcaatg
    25621 gcaaccatat tgaaattata attaacttga aggtctgtgt atttcaacaa ataatttaga
    25681 atggtttggc tatctgcatc ttttttcaac tcaatagcta tgcgaagacc tgtgcgatca
    25741 gattcatcac gtacttctac gatgcctggg actttattgt taacacgaac atcgtcaatc
    25801 tttttgacca agactgcttt gttaacttca taaggaatct cagtgacaat aatttgttgt
    25861 ttaccacctt taagttcctc gatttctgtc ctagagcgaa caacgacacg tcccttacct
    25921 gtttcgtagg cttttttgat ttcgtcagct ccttggataa tgcctcctgt cgggaaatct
    25981 ggcccaggca aaaactccat taatttctct aagctagcct tgggatggtc aatcatgtaa
    26041 acaacggcat caatcacttc tgacaaattg tgcggtggaa tatctgtcgc ataacctgcg
    26101 gaaataccag aagacccatt gacaagtaag ttaggaaaag ctgctggtaa aacggtgggt
    26161 tctttttctg tgtcatcaaa gttccacgca aaagagaccg tatttttctc aatgtcttga
    26221 agaagataac ccgcaatttc agacaagcga gcttctgtat aacgcatagc cgcaggcgga
    26281 tcgccatcca ttgaaccatt atttccgtgc atttccacaa gaatttcacg gttcttccaa
    26341 tcttgactca tccgtaccat ggcatcataa atagaggaat ccccatgcgg gtggaaattc
    26401 cccatgatat taccaactga tttggctgat ttacggtaac ctttttcaaa agtattacca
    26461 tccttattca tcgaataaag aatgcggcgc tgaacgggtt tcaatccatc tcgaatatca
    26521 ggaagtgccc gttcctgaat aatatacttg gaataacggc cgaagcgttc tcccataata
    26581 tcctcaaggg acatgttttg aatgtttgac atattcaaat agctttcttt ttcattattt
    26641 attaattacc taaaaaacaa tcgtctttag cacttgtaat tatctgtgag aaacttgtat
    26701 gactaaaaca ccgtattttc ttctaaggta aacttgacgt tgtcctcgat ccactgacgg
    26761 cgtggagcgg ctttgtcacc catcaaaaca gaaacgcgtc gttctgctct tgctaaatca
    26821 tcaatagtaa cacgaataag tgttctggtt tcagggtcca tagtggtttc ccataattgg
    26881 ttagcattca tttcacccag tcctttatag cgttgaagaa tagccccctt gccaaattct
    26941 ctgcgcagat cttccaattc accatctgtc caagcgtagg acactttctc tgttttacct
    27001 ttaccttttg acattttata aagcggggga agcgcaatat aaacgtgacc tgcttccacc
    27061 aacggtcgca tataacggta aaagaaagtc agcaaaagag tctgaatatg agccccatcg
    27121 gtatcagcat cggtcatgat aataatctta tcatagttga tatcctcgag gttaaagtca
    27181 gctcccactc cagctccaat ggtataaacc atagtgttaa tttcttcatt tttcaagatg
    27241 tcaaccatct tagctttttc ggtatttaaa actttgccac gtaatggtaa aatagcctga
    27301 aatttgcggt ctcgtccttg tttggctgaa cctcccgcag aatctccttc gaccagatac
    27361 aattcatttt tcttggcatt tttggactga gctggggtta attttcccga caacaagcct
    27421 ttgtcttttt tgtttttctt accattacgt gagtcatcac gcgcttttcg agcagcttcg
    27481 cgagcatctc tagctttaat ggctttgcga actagatgag aagctacttc tccattttcg
    27541 agtaaaaaga aggttaattt ttcagaaaca atgctctcta caataggtct agctaaggga
    27601 cttcccaatt tgtctttggt ctgtccttca aattgcaagt gctgctcagg aactaagata
    27661 gataatactg ctgagagtcc ttctcgataa tctgagccct ctagattttt atccttttct
    27721 tttaagagat tggttttacg agcatagtca ttcatcgctt tggtaatagc tgactttagt
    27781 cccgtttcat ggcttccacc atctttggtg cgcacattgt ttacaaagga taagatattg
    27841 tcggagaaac catcgttata ctgcaaagca acctcgactt gaaagtcttg gtcttgacct
    27901 tccatgtaaa taacaggtgt caaggtttcc ttatcttcat tgaggtattc gacgaaatct
    27961 tgaaccccat tttcataatg aaactcttca ataatcgggt catctccacg aagatctgtc
    28021 aagctcatct tgacattttt caaaagaaaa gcagattctt tcaatcgttc tgaaatggta
    28081 ttgaacttaa agtcaatagt tgaaaaaatc ttatcatcag gcataaaggt tacaaccgtt
    28141 cctgatttag acttaggagc tgtgccaact tttttaaggg ttgtaacagg tttcccacca
    28201 ttttcaaagc gctgacgata cactgacccg tctcttgtga tttcgacttc taaccaggca
    28261 gacaaagcat tgacaacaga ggagccaaca ccgtgcaaac cacctgacgt tttgtagcca
    28321 ccctgaccaa atttaccacc tgcatgaaga atcgtaaaaa taacttgaac ggtgggaatc
    28381 cctatggcat gctgacctgt tggcattcca cgtccgctat ctgccacact gaccgagcca
    28441 tctttattga taacaacctt aatatcatct ccaaaaccag acaaggcctc atcgacagca
    28501 ttatcaacaa tttcccaaat caggtggtgc aatcccgtag catctgttga accgatatac
    28561 atccctggac gcttgcgaac agcatctaac ccttctagga cttggatagc atcgtcatta
    28621 taattattaa ttgtaatttc tttcttagtc aacaccgacc tccagacagt ttcatctttt
    28681 ttatcttaca agttttttac caattttgca aaataatttg ctaatttttt ccgaattctg
    28741 ttccaga
//
LOCUS       DAUNLR010000020        28469 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUNLR010000020 DAUNLR010000000
VERSION     DAUNLR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28469
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.020"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..1123
                     /gene="hasA"
                     /locus_tag="VLL59_000883"
     CDS             <1..1123
                     /gene="hasA"
                     /locus_tag="VLL59_000883"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HER6509018.1"
                     /translation="KLGLSFLYEPFKGNPHDYKVAAVIPSYNEDAESLLETLKSVLAQ
                     TYPLSEIYIVDDGSSNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFER
                     SDADVFLTVDSDTYIYPNALEELLKSFNDETVYAATGHLNARNRQTNLLTRLTDIRYD
                     NAFGVERAAQSLTGNILVCSGPLSIYRREVIIPNLERYKNQTFLGLPVSIGDDRCLTN
                     YAIDLGRTVYQSTARCDTDVPFQLKSYLKQQNRWNKSFFRESIISVKKILSNPIVALW
                     TIFEVVMFMMLIVAIGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMIKHPASFL
                     LSPLYGILHLFVLQPLKLYSLCTIKNTEWGTRKKVTIFK"
     gene            1159..2367
                     /gene="hasB"
                     /locus_tag="VLL59_000884"
     CDS             1159..2367
                     /gene="hasB"
                     /locus_tag="VLL59_000884"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HER6509019.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2549..3463
                     /gene="hasC"
                     /locus_tag="VLL59_000885"
     CDS             2549..3463
                     /gene="hasC"
                     /locus_tag="VLL59_000885"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HER6509020.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQTPGSGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
     gene            3771..4184
                     /gene="yaaA"
                     /locus_tag="VLL59_000886"
     CDS             3771..4184
                     /gene="yaaA"
                     /locus_tag="VLL59_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HER6509021.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRIGDKISLPDQDLIITIVEPSQEEKEQFAEEIAEKTRVAALVKQINQANKK
                     TSSKHKNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            4186..5292
                     /gene="recF"
                     /locus_tag="VLL59_000887"
     CDS             4186..5292
                     /gene="recF"
                     /locus_tag="VLL59_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HER6509022.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(5347..6210)
                     /locus_tag="VLL59_000888"
     CDS             complement(5347..6210)
                     /locus_tag="VLL59_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HER6509023.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
     gene            complement(6413..7894)
                     /gene="guaB"
                     /locus_tag="VLL59_000889"
     CDS             complement(6413..7894)
                     /gene="guaB"
                     /locus_tag="VLL59_000889"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HER6509024.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
     gene            complement(8202..9224)
                     /gene="trpS"
                     /locus_tag="VLL59_000890"
     CDS             complement(8202..9224)
                     /gene="trpS"
                     /locus_tag="VLL59_000890"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HER6509025.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIRIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     misc_binding    complement(9279..9520)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9643..10515
                     /locus_tag="VLL59_000891"
     CDS             9643..10515
                     /locus_tag="VLL59_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HER6509026.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     gene            10594..12213
                     /locus_tag="VLL59_000892"
     CDS             10594..12213
                     /locus_tag="VLL59_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HER6509027.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            12296..14872
                     /locus_tag="VLL59_000893"
     CDS             12296..14872
                     /locus_tag="VLL59_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HER6509028.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKINAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLSLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(15369..15442)
                     /locus_tag="VLL59_000894"
     tRNA            complement(15369..15442)
                     /locus_tag="VLL59_000894"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15406..15408),aa:Asn,seq:gtt)
     gene            complement(15476..15547)
                     /locus_tag="VLL59_000895"
     tRNA            complement(15476..15547)
                     /locus_tag="VLL59_000895"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15512..15514),aa:Glu,seq:ttc)
     gene            complement(15743..16517)
                     /locus_tag="VLL59_000896"
                     /pseudo
     CDS             complement(15743..16517)
                     /locus_tag="VLL59_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            16682..16755
                     /locus_tag="VLL59_000897"
     tRNA            16682..16755
                     /locus_tag="VLL59_000897"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16716..16718,aa:Arg,seq:tct)
     gene            complement(16913..17392)
                     /gene="rlmH"
                     /locus_tag="VLL59_000898"
     CDS             complement(16913..17392)
                     /gene="rlmH"
                     /locus_tag="VLL59_000898"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HER6509029.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            17604..18827
                     /locus_tag="VLL59_000899"
     CDS             17604..18827
                     /locus_tag="VLL59_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HER6509030.1"
                     /translation="MPSMKHILKSLSILLVGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGNNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            18886..19692
                     /locus_tag="VLL59_000900"
     CDS             18886..19692
                     /locus_tag="VLL59_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HER6509031.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            19925..21280
                     /gene="dnaA"
                     /locus_tag="VLL59_000901"
     CDS             19925..21280
                     /gene="dnaA"
                     /locus_tag="VLL59_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HER6509032.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            21435..22571
                     /gene="dnaN"
                     /locus_tag="VLL59_000902"
     CDS             21435..22571
                     /gene="dnaN"
                     /locus_tag="VLL59_000902"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HER6509033.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            22646..22843
                     /locus_tag="VLL59_000903"
     CDS             22646..22843
                     /locus_tag="VLL59_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HER6509034.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            23173..24288
                     /gene="ychF"
                     /locus_tag="VLL59_000904"
     CDS             23173..24288
                     /gene="ychF"
                     /locus_tag="VLL59_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HER6509035.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            24358..24927
                     /locus_tag="VLL59_000905"
     CDS             24358..24927
                     /locus_tag="VLL59_000905"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HER6509036.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            24930..28433
                     /gene="mfd"
                     /locus_tag="VLL59_000906"
     CDS             24930..28433
                     /gene="mfd"
                     /locus_tag="VLL59_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HER6509037.1"
                     /translation="MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLMNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GIFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFTDNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYKRLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEREIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVSELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYISDERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
BASE COUNT         9469 a         4974 c         4913 g         9113 t
ORIGIN      
        1 taaacttgga ttatctttcc tttatgagcc atttaaagga aatccacatg actataaagt
       61 tgctgctgta attccttctt ataatgaaga tgccgagtca ttattagaaa ctcttaaaag
      121 tgtgttagca cagacctatc cgttatcaga aatttatatt gttgatgatg ggagttcaaa
      181 cacagatgca atacaattaa ttgaagagta tgtaaataga gaagtggata tttgtcgaaa
      241 cgttatcgtt caccgttccc ttgtcaataa aggaaaacgc catgctcaag cgtgggcatt
      301 tgaaagatct gacgctgacg tttttttaac cgtagattca gatacttata tctatccaaa
      361 tgccttagaa gaactcctaa aaagcttcaa tgatgagaca gtttatgctg caacaggaca
      421 tttgaatgct agaaacagac aaactaatct attaacgcga cttacagata tccgttacga
      481 taatgccttt ggggtggagc gtgctgctca atcattaaca ggtaatattt tagtttgctc
      541 aggaccattg agtatttatc gacgtgaagt gattattcct aacttagagc gctataaaaa
      601 tcaaacattc ctaggtttac ctgttagcat tggggatgat cgatgtttaa caaattatgc
      661 tattgattta ggacgcactg tctaccaatc aacagctaga tgtgatactg atgtaccttt
      721 ccaattaaaa agttatttaa agcaacaaaa tcgatggaat aaatcttttt ttagagaatc
      781 tattatttct gttaaaaaaa ttctttctaa tcccatcgtt gccttatgga ctattttcga
      841 agtcgttatg tttatgatgt tgattgtcgc aattgggaat cttttgttta atcaagctat
      901 tcaattagac cttattaaac tttttgcctt tttatccatc atctttatcg ttgctttatg
      961 tcgtaatgtt cattatatga tcaaacatcc tgctagtttt ttgttatctc ctctgtatgg
     1021 aatattacac ttgtttgtct tacagcccct aaaactttat tctttatgca ccattaaaaa
     1081 tacggaatgg ggaacacgta aaaaggtcac tatttttaaa taatatgtgc atcgagtagt
     1141 tagagaagga gtaattttat gaaaatagca gttgctggat caggatatgt tggattatca
     1201 ctaggagttc ttttatcact tcaaaacgaa gtcactattg ttgatattct tccctctaaa
     1261 gttgataaga ttaataatgg cttatcacca attcaagatg aatatattga atattactta
     1321 aaaagtaagc aattatctat taaagcaact ttagatagca aagcagctta taaagaagcg
     1381 gaactggtca ttattgccac acctacaaat tacaacagta gaattaatta ttttgataca
     1441 cagcatgttg aaacagttat caaagaggta ctaagcgtta atagccatgc aactcttatc
     1501 atcaaatcaa caattccaat aggtttcatt actgaaatga gacagaaatt ccaaactgat
     1561 cgtattatct tcagccctga atttttaaga gaatctaaag ctttatatga caacttatat
     1621 ccaagccgaa ttattgtttc ttgtgaagaa aacgattctc caaaagtaaa ggcagacgca
     1681 gaaaaatttg cacttttatt aaagtctgca gctaaaaaaa ataatgtacc agtacttatt
     1741 atgggagctt cagaagctga agcagtaaaa ctatttgcca atacttattt agcgttaagg
     1801 gtagcttatt ttaatgagtt agacacttac gcagaatcga gaaaattaaa tagtcacatg
     1861 attattcaag gaatttctta tgatgatcga ataggaatgc attataataa cccatcattt
     1921 ggttatggag gttattgtct acctaaagat acgaagcaat tattggcaaa ttacaataat
     1981 attccccaaa cgctaattga agctatcgtt tcatcaaata atgtgcgcaa gtcctatatt
     2041 gctaagcaaa ttatcaacgt cttagaagag cgggagtccc cagtaaaagt agtcggggtt
     2101 taccgtttaa ttatgaaaag taactcagat aattttagag aaagtgctat caaagatgtt
     2161 attgacattc ttaaaagtaa agacattaag ataattattt atgagccaat gttaaacaaa
     2221 cttgaatctg aagatcaatc tgtacttgta aatgatttag agaatttcaa gaaacaagca
     2281 aatattatcg taactaatcg ctatgataat gaattacaag atgttaaaaa taaagtttac
     2341 agtagagata tttttaatag agactagcca tgtcttcatc tataacaata atattcattt
     2401 ttactttaaa agaactgcag ttggtggtat gattgagcac tatgaaatag tcgaaaaatc
     2461 atatgaaaac gtaacatgat gtcaaattaa ttccgttctg aaaacgaatg tcactaagcc
     2521 atagattata aaaagtgagg agttactgat gaccaaagtc agaaaagcca ttattcctgc
     2581 tgcaggtcta ggaacacgtt ttttacctgc taccaaagct cttgccaaag agatgttgcc
     2641 catcgttgat aaaccaacca tccagtttat cgtcgaagaa gcgctaaaat ctggcatcga
     2701 ggaaatcctt gtggtgaccg gaaaagctaa acgctctatc gaggaccatt ttgattcaaa
     2761 ctttgaatta gaatacaacc tccaagctaa ggggaaaaat gaactgttga aattagtgga
     2821 tgaaaccact gccattaacc ttcattttat ccgtcaaagc cacccaagag gactgggaga
     2881 tgctgtctta caagccaaag cctttgtggg caatgaaccc tttgtggtca tgcttggaga
     2941 tgacttaatg gacattacaa atgcatccgc taaacctctc accaaacaac tcatggagga
     3001 ctatgacaag acgcatgcat ccactatcgc tgtgatgaaa gttcctcatg aagatgtgtc
     3061 tagctatggg gttatcgctc ctcaaggcaa ggctgtcaag ggcctttaca gtgtagacac
     3121 ctttgttgaa aaaccacaac cagaagatgc gcctagtgat ttggctatta ttggtcgtta
     3181 cctcctaacc cctgaaattt ttgatatttt ggaaagacag acccctggat caggtaacga
     3241 agtgcaactc acagatgcta tcgataccct caataaaact cagcgtgtct ttgcacgaga
     3301 atttaaaggc aatcgttacg atgttgggga taaatttgga ttcatgaaaa catctatcga
     3361 ctatgcctta gaacacccac aggtcaaaga ggacttgaaa aattacatta tcaaactagg
     3421 aaaagctttg gaaaaaagta aagtaccaac acattcaaag taatgtgttg gtactttact
     3481 tttttccttg tttatagcaa cttaagttta tatcttgaaa attgtcaacg ttccaaaata
     3541 taaaagcttt gtgttataca actttactag agggacatat taataatagg atttatacgt
     3601 agaaaaatga taaacataag tacagctttt gttaaaacta attaacaaga acttcaaaac
     3661 taaatagtta tttggacgag tatgatactt tataaatagc tcttattcag ctattattat
     3721 ttatttctgt tttatgctat aatgacttga atgacaaaat ggagatgaca atgatataca
     3781 aattatttac agaatttatc accctacaag cccttcttaa agaattagga attatccaaa
     3841 gtggtggcgc tatcaaggga tttctcgctg aaacaaccgt tctatttaat ggtgaagatg
     3901 agaaacgtcg aggcaaaaaa atcagaatag gggataagat ttctctacct gaccaagact
     3961 taattatcac tattgttgag cctagtcaag aagaaaaaga acaatttgcc gaagaaatag
     4021 ctgaaaagac acgtgtagcg gctctagtga aacaaattaa ccaagctaac aaaaagactt
     4081 cttctaaaca taaaaatcgt caatctacta ccaaaaaatc actaagagca actaagaaaa
     4141 ctaaaggtaa accaactgca cctgtccgct tcccaggtat ctagtatgtg gattaaagag
     4201 ttagagttaa aacattatcg caattatgac cacctgcttg cctcattttc gtcgggttta
     4261 aatgtcttta tcggtaataa tgctcaagga aaaaccaatt ttctcgaggc aatctatttt
     4321 ctatcactta ctagaagtca tcgcacgagg gctgataaag aattgattca ttttgatcac
     4381 tcaactgttt ctcttactgg taagattcag cgtattagtg gtactgttga tttagaaatc
     4441 aatctatcag ataaaggacg tgtgacaaag attaatgcgc taaagcaagc aaaattatct
     4501 gattatattg gaacgatgat ggttgtgctt tttgcaccag aagatttgca actagttaag
     4561 ggagcaccta gccttcgtcg caaatttatc gacattgacc ttggtcaaat taagcctgtt
     4621 tacttatctg agttatccca ttataaccac gtgcttaaac agcgtaatag ctatttaaaa
     4681 agtgcccaac aaattgatgc cgcttttcta gctgttctag atgagcaatt agctggctat
     4741 ggagcccgtg tcatggaaca tcgtattgat tttatcaatg cgttagagaa agaagcaaat
     4801 actcatcacc aagccatctc aaatggttta gaaagtctct ctctctccta tcagtcgtca
     4861 gttgtctttg acaaaaaaac taatatttac caacaatttt tacaccaact tgaaaaaaat
     4921 catcagaaag atttcttccg taaaaacact agcgttggtc cacatcgcga tgacttagcc
     4981 ttttacatta acgggatgaa tgctaacttt gctagtcaag gtcagcaccg cagccttatt
     5041 ctttccttaa aaatggctga agttagttta atgaaggcct tgactggaga taatcccatt
     5101 cttttactag acgatgtcat gagcgagcta gacaatacac gacaaacaaa gttacttgaa
     5161 acagtaatta aagaaaatgt ccaaaccttt atcacaacaa caagtttgga tcacctgtca
     5221 cagttgccag aaggtatccg tatttttcac gtgacaaaag gaaccgttca aattgattct
     5281 gatattcact aataacatca aaaaagggtt cagttaaact gagccttttt tgatattatg
     5341 tggcgattaa gatttgacca cacctaataa aatagcacct acgataaaac aaataattcc
     5401 tgtgacaacc caacgcattt cttttttggt tttggtttcg cctaggaata aaatgcctcc
     5461 gacaatcgaa atgatagcac ctaattgtga gaaactaaag gcaatagcaa gtcctgcttt
     5521 tgatgcagct aaaagcataa aaatattccc aatgccccaa agtaatccaa caacgctatt
     5581 tttaatcaca tactggtcaa tggaaatttt aaatgacatg aaagttatag ctcctaaaac
     5641 catacctact gccatgggta aaatgactga caaaacttca aatttcatga tgttattaaa
     5701 taatacagca tacatcacgt aaccaattgt tgaataagtg agcgccctaa atccttttga
     5761 aaaattatga aggtgattga cttgtgcatt agcatcatct tgtttactag aaaagtaaaa
     5821 accaacaatc agaagtaata gtgctagact tcctactaca aattgcatag gtcttgtcca
     5881 ttcatgaaaa acgaggacac caatcaaact tcccagaaca agttgagagc cacttgacaa
     5941 aggattggca acggagactc ccatgtattg catggcatga aattgaccag tttgaccaat
     6001 tgaccagata aaaccaccca atattccaaa aagccaaagt tgcagtgtca tctcaggtct
     6061 aacaattaac caaacagcta atgaaaataa taaagcccca aaagtcattc ctagagtttg
     6121 ttgcgaaggt tttcctccaa ttttgttact aacaaatcca atgcttcccc atgtaaacat
     6181 gggaataagt gcataaaaaa taccttccaa aatgttatct cctttatagt aaatctttaa
     6241 agattataat aattctatca taaaatggtt tcatgtaaag actaattata gcttatttac
     6301 taagaaaaaa caataaaagt tatccgaaaa ttgttattat attttatcat tttttaatat
     6361 aaaaaaagag ctggcacaat atgtcagccc ttagagttac taaattaaat tatcagtgca
     6421 cagaatagtt tggtgcttcg tttgtgattt ggacatcatg tggatgactt tcaatcaagc
     6481 ctgcacctga catttcaaca aattgagcat tttcatgtaa ttcttgaatg tcacctgcgc
     6541 caacatagcc catacctgag cggataccac ctaacatttg gaagacaata tctgaagcag
     6601 ctcctttata agcaacacgg ccttcaatac cttctggaac tagtttatta gcttcattga
     6661 cggaaccttg gaagtaacga tcgcttgatc ctttcttcat agctgcaatg gaacccattc
     6721 cacgataagt tttgaactta cggccttggt agatttcagt ttcacctgga gcttcatcag
     6781 tacctgcaaa cattgatcca agcataacag cattaccgcc ggctgcaaga gccttaacaa
     6841 tatcgccaga atacttgata ccaccatcag caataatcgt tttgccatat tcacgagcaa
     6901 cagcagcagc atcgtaaata gcagtcactt gaggaacacc gacacctgca accacacgag
     6961 tggtacagat agatccggga ccaataccca ctttaacaac atcaacacct gcatcataaa
     7021 gagcacgcgc accttcagca gtggcaatat ttccagcaat caaagtacga tttgggaaat
     7081 gagcacgaat ttcagcaatt tttctaagaa caccagccga atgaccatga gctgtgtcaa
     7141 taacaatcgc atctgcacca gcttcaaaca aggcctcggc acgctcaaaa gtatctgagg
     7201 taacacctac cgcagcagcg accagaagac ggccaaattc atctttagca gcatgtggga
     7261 attcgattac tttttcaata tctttgatag tgattaaacc agacagacga ccgctattat
     7321 caaccaaagg aagtttttca atacggtgtt catgaagaat acgttctgca gtttcaagat
     7381 ctgtaccaac agcagccgta acgaggtgct cactagtcat atgttcagag attggtgcat
     7441 tgtaatcaga aataaaacgc atatcacgat tagtaatgat accgaccaac ttacggtttg
     7501 ctaaagtttc aacaattggc acaccactga tacggtagcg ctgcattaat tcttcagctt
     7561 ctgaaacctt gtgttcaggt gttaagaaga atggatcaat gatgacacca ttttcagaac
     7621 gttttacctt gcgaacttct tctgcttgct cagtaataga catgttttta tgaataacac
     7681 ctaaaccacc cgcacgcgca attgcaatag ccattttact accagtaacc gtatccatag
     7741 ctgctgtaat aataggaata tttaatgtca aattgtcggc gagctttgtc tttaaatcaa
     7801 cttcatttgg aagaacatga ctctctgccg gaataagcaa gacatcgtca aaagtgtagc
     7861 cttttttcaa aaatttagtg tcccaatttg acatccagat aatcctcttt tcttttattt
     7921 ttagggaata ttaccctggt ctatttttta ttgttactat catatcacgc taaaatcatt
     7981 tgtcaataaa atattcctac agctgaagtc actatcagca taatatatca gtattatccg
     8041 ttttttatta atcaaaaaat tcatttgggt cttattttta atcaaaaata agactatata
     8101 aaacataatc tctactatcc tgtaaagaaa tgacaaatta ggtcctgctt tgataatatt
     8161 aattatctta tcattactaa cttagctttt tctctaaaac attaaaaata attaataccc
     8221 attgctgact tcacttctga taaagtcttg gctgccacag ttcttgcttt ttgactacct
     8281 tcttgtaaca tacggaacac ctctcccata tctttagcgt actccaaacg tctttcacga
     8341 ataggtgcta attcacgttc taaaatatct agaaggtagc gtttcgtttt cacatctcct
     8401 aaaccacctc tttgataatg ctctttcatt gcttcgatat cagcttgatc ttcttttcta
     8461 gcaaaaatat ccaaataatg aaagaccata ttcccttcaa tttgaccagg atcttctatt
     8521 ctaatatgat ttggatcagt atacatgctc atcacttttt tgcgaacggt atctgcatca
     8581 tctgaaagat agattccatt tcccaatgat ttagacattt tggcattgcc atcaagacca
     8641 ggtaagcgtc cagctttttc attttctgga taaatgcctt caggttctac taaacagtct
     8701 gtatggtaag tatgattaaa acttctcaca atttcacgtg tttgttcaat catcggtttc
     8761 tggtcgttac ctacaggtac taaattcgct ttaaatgctg taatatcagc ggcctgtgat
     8821 actggataaa ccaaaaaacc agatggaata ctttcgccaa aacctttctg agcaatttca
     8881 gttttaacag tgggatttct ttccaaacgt gctaatgata ccagattcat ataatacatg
     8941 ctcaattcag ctagctctgg aatctgactt tgaataaaaa tcgttgattg cttcggatcc
     9001 aaaccgacag agaggtaatc caaggcaaca tttccaatag attcttgaat taattcggat
     9061 tctttagcat gatccgtcag tgcctgttga tcggccaaga aaacaaacat cttatacttg
     9121 ttttcatttt gtaaaaagac acgattttta agacttccga cataatgacc taaatgtaat
     9181 tttccagttg gtctatctcc agttaaaata ataggttttg tcatcatttt ctccctaact
     9241 atctcttgat atagcaaaaa gtccccacgc tattaaaacg tgagggcgtt attacaagta
     9301 atacgcggta ccacctcaat tagcatctgc tttatcaaaa cgagatacta tctcaatctt
     9361 ctcaatgaaa gaagctgcac ggtaaggggt gccaacctga aagttatggt ttcctttcaa
     9421 ataatcatta gtccatttca ccttttctgt tgttagcttg caccaaccac taactctcta
     9481 aaaacatgaa aagaatactc ttctaattca aatttattct atgaaatttt aaacttcttg
     9541 tcaagttcac cagatttttt gaaaatatga cttgacggtc tcagtacatt taagagataa
     9601 tgagtctact atttttaacc agttataaag gagattaaaa gcatgaaaaa acgagggatt
     9661 gatttactac ttgtcacaat tggctcattc ataacagcta ttggtttcaa tacaatgttt
     9721 gtcgacaatc atattgcatc agggggtatg gttggtattg cagttgttat aaaagctcta
     9781 tttggcatta gtccgtcgct ttttttaatg gctagtaata ttcccttatt attaatgtgt
     9841 tacttctttc ttggaaaaca aaattttatt aaaacacttt atggttcttg gatatatcct
     9901 attgccatcc gttcaaccaa ttcattacct actctgacac acaatcagtt gttagcagct
     9961 atttttggtg gtattatctg tggcattggt ttaggaatgg ttttttgggg aaactcttcg
    10021 acaggaggaa ctggaattct aacacaaata cttcataaat actctccttt atctcttgga
    10081 gttgcaatga caattgtaga tggtattagt gtccttatgg gatttattgc actttctgca
    10141 gatgacgtga tgtattctac gattggactt ttcgtaattg gttatgtgat tagcgttatg
    10201 gaaaatggct ttgactcatc caaaaatgtt atgattattt ccaaagatta tcaagctatt
    10261 cgagaatata tcacaactgt tatggatcgt ggagtgacta aacttcctat tcgcggtggt
    10321 tatactactt ctgataaaat tatgttaatg gctattgtat caagtcacga attacccact
    10381 ctccaagaaa aaatcctcga aattgacgac acagccttta ttgttgtcat gccagcagct
    10441 caagttatgg gaagaggatt tagtttgact aaacaataca aacgtgaaga caaagacgtt
    10501 ttattgccta tgtagtgatt agcccttttc tgattgaaaa aggggactat tttaggtaca
    10561 atgaagctta gataaataag atgaggtgac aaattgctta cagtttctga tgtatcacta
    10621 cgctttagtg atcgaaaact ttttgatgat gtaaacatca aattcacagc cggtaatact
    10681 tacggcttaa tcggtgccaa tggtgccgga aaatcaactt tccttaaaat ccttgccgga
    10741 gatattgaac caagtactgg tcatatctct ttaggtcctg acgaacgcct ttctgttctt
    10801 cgacaaaatc actttgacta tgaagaagag cgtgctattg atgttgttat catgggaaat
    10861 gaacaactct acaatatcat gaaagaaaaa gatgctattt acatgaaagc tgacttttca
    10921 gaagaagacg gagttcgtgc cgctgagctg gaaggtatct ttgctgagtt aggtggctgg
    10981 gaggcagaaa gtgaagcttc tcaacttctc caaaatctaa atattccaga agaccttcac
    11041 taccaaaata tgagtgaact ggctaatgga gataaggtga aagtccttct tgctaaagcg
    11101 ctctttggta agcctgacgt tctattactt gacgaaccaa ccaatggtct tgatattcaa
    11161 tctatttcat ggttggaaga tttcttgatt gattttgaaa atacagttat cgttgtttcc
    11221 catgaccgtc acttcttgaa taaagtatgt actcatatgg ccgaccttga ctttggtaaa
    11281 atcaaactct ttgtgggtaa ctacgatttc tggaaacaat cttctgagct ggccgctcgt
    11341 ttacaagctg accgcaatgc taaagcagaa gagaaaatca aagaattaca agaattcgtt
    11401 gcccgtttct cagctaacgc ctctaaatca aaacaagcaa cctctcgtaa aaaaatgctt
    11461 gataagattg aattagaaga aattgttccc tcaagtcgta aatacccatt tattaatttt
    11521 aaagcagagc gtgaaatggg aaatgacttc ctcactgttg aaaatctttc tgtaacgatc
    11581 gatggagaga aaatcattga taatatcagt ttcattttac gtccaggtga caaagctgct
    11641 attattggtc aaaatgatat tcaaacaacc gctcttatgc gtgctttagc agatgatatt
    11701 gactacgaag gaaccattaa atggggagtg acaacaagtc gttcttactt gcctaaagac
    11761 aattcaaaag attttgccac ggaagaatct attcttgaat ggttacgtca atttgcctca
    11821 aaaggtgaag atgacgatac ttttttacgt ggtttcctag gacggatgct tttctctgga
    11881 gacgaagtta aaaaatctgt taacgttctt tccggtggcg aaaaagtgcg tgtcatgctt
    11941 tctaagttga tgctattgaa atcaaacgtt cttattcttg atgatccaac aaatcacttg
    12001 gatttggaat ctatttcaag tcttaatgat gggatcaaag acttcaaaga atctgttatc
    12061 tttgccagtc atgaccatga atttattcaa acgattgcta accacatcgt tgttatttca
    12121 aaaaatggtg ttatcgaccg tatagatgaa acttatgacg aattccttga caatccagaa
    12181 gtccaagccc gagttgctga actttggaaa taaaacctta tgataaatga ggtggctaag
    12241 aagatctctt cctagcctct tttttaaaat ttgtaaacga aagaccatat aatttatgaa
    12301 aaataataat aaatggataa ttgctggact tgctagtttt ttgttccctc ttagtattat
    12361 atttatcatc cttctatcga tgggcattta ttataatagt gataaaacaa ttctagctag
    12421 tgatgctttt catcagtatg ttatttttgc gcagaacttt cgtaacatca tgcacggttc
    12481 tgatagtttt ttttatacct ttacaagcgg actagggata aatttttatg ctttaatgtg
    12541 ttattatctt ggcagtttct tttctccatt acttttcttt tttaatttaa cctctatgcc
    12601 agatgctatc tatttgttta ccttgataaa atttgggtta ataggattag ctgcatgcta
    12661 ttcttttcat agattatatc caaaaatcaa tgctttcttg atgatttcca tctcagtttt
    12721 ttatagctta atgagcttct tgacaagtca aatggaacta aattcttggt tagatgtttt
    12781 cattcttctt ccacttgttg tacttggatt aaataaactt atcacagaaa ataaaaccag
    12841 aacttattat ctttcgatat cattattatt cattcaaaat tactactttg gctacatgat
    12901 tgctcttttt tgtattcttt acgccttagt ttgtctttta agtctcaatg attttaacaa
    12961 aatgtttatc gcttttgtta ggtttacagc tgtgtcaata tgtgctgctt taacaagtgc
    13021 tctggtaata cttcctacct atctagattt gtcaacttat ggagagaatc tatccccggt
    13081 aaaacagtta gttacgaaca atgcttggtt tttggatata cctgctaagc tctcaatagg
    13141 agtgtacgat actaccaagt ttaatgctct gcctatgatt tacgtaggat tatttcccct
    13201 aatgcttagt gttatttatt ttactttaga aagtatccct ttaaaaataa aattagccaa
    13261 tgcctgcttg ttaactttta ttataataag tttttaccta cagccacttg atcttttttg
    13321 gcaggggatg cactcaccaa atatgttttt gcaccgctac gcttggtctt tttccatagt
    13381 tatcctatta ctcgcatgtg agactctctc tcgactaaaa gaagtgactc aaataaaagc
    13441 aggttttgct tttattttcc tcattatact gacatctctt ccttatagct tttctcaaca
    13501 atataatttt ctacctttaa ctcttttttt acttagtgtt tttttattat taggttatac
    13561 tatttcacta ttttcgttta gaaattctca aatcccatct acttttattt ctgctttcat
    13621 acttatcttt agccttcttg aatcagggtt aaacacctac taccagcttc aaggaattaa
    13681 taaggagtgg ggattcccat cacgacagat atataatagt caattaaagg atattaacaa
    13741 ccttgtcaac tctgtgtcaa aaaatagtca accttttttt agaatggaaa ggctacttcc
    13801 ccaaacaggg aacgatagca tgaaatttaa ttattacggc atttcacaat tttcctctgt
    13861 aagaaataga ctatctagtt ctttattgga tcgattggga tttcagtcta aaggcacaaa
    13921 tttaaacctt agataccaaa acaatactat tattatggac agtctacttg gtataaaata
    13981 taatcttagc gaaggacctc taaataaatt tgggtttaca aaactaaaaa ctagcgggaa
    14041 tactactctt tatcaaaatc actatagtag ccctttagct atattaacac gtaatgttta
    14101 caaagatgtc aacctaaatg tcaataccct tgataaccaa accaaattac ttaaccaact
    14161 aagtgggaaa tctttaacct attttaactt acagccagct caacttattt ctggtgctaa
    14221 tcaatttaac ggacaaatat ctgcacaagc ttctgattat caaaactccg ttacccttaa
    14281 ttatcaaatt aacatcccta aacatagtca actctatgtt agcataccca atattatatt
    14341 ttcaaatcct gatgctaaag aggtgcgtat tcagacagat aatcataatt tcatatatac
    14401 tacagataac gcttactctt tttttgattt aggatatttc gccgatgcca aagttgctac
    14461 attttcgttt gtttttccaa aaaataaaca aattagtttt aaggaacctc atttttatag
    14521 tttgtctatt gaatcttacc ttgaagcaat gaatagtatt aaacaaaaaa atgttcatac
    14581 ttacgctaaa agtaatacgg taatcactga ttataattca aaaacgaaag gttctcttat
    14641 ttttacactt ccttacgata aaggttggtc agcacaaaaa gatgggaaaa atcttccagt
    14701 caaaaaagca caaggaggat ttctatcagt tactattcct aaaggaaagg gacgtgttat
    14761 ccttaccttt attcctaatg gttttaaatt agggttatct ctatcttgcg taggaattat
    14821 cgcttatatg cttttgtata agtacataga tataaagtct aaattacttt agtccaaaaa
    14881 aatcagattt ttttatcaat ttggcaaatg agtcaatata ctaaaagcat ctcaagagct
    14941 agacaaatat tctaatactt gagatgcttt tatcgatttt actaataaac tcaaataata
    15001 taaaggtcag atttttcgtg agggttaatg ttaaactact ctctttcaaa gattgaaatg
    15061 acaataatca tcgctgatac gatttcaatc ttttgactcc ttacaataat cttatattca
    15121 tcagtattaa atgggagaca tgctttcaaa atgtaaaaaa ttaagcttca gttaatgttt
    15181 gtaattaaac ttaatgttat catctataca attaaagaac agaacttcta tttttatgca
    15241 aaatacaatc ctgttagttc acaatgctgt atttagtggt ttaataatta gtaaattgag
    15301 tatttgacct gagtatctgt tttactaaat aaaaaaatcc taagattatc ttaggaaata
    15361 tcttatcact ccggcagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta
    15421 ctaccaactg agctatgccg gaaaaagaaa aaaattgcca aaatgacaat tgcgatagtc
    15481 cgtacgggat tcgaacccgt gttaccgccg tgaaaaggcg gtgtcttaac cccttgacca
    15541 acggaccaga agttttggag gatatctcct taacactctt actattatag cagattgatt
    15601 ttttttgtct atactttttt taaaaaaaat ttgatttttt ttaaaccgca agttgtcaag
    15661 tcaagtgcaa cgagttcata gataactaga gttccagagg ttaagctgtt cgggatagct
    15721 caaacaggaa ttttgaggat tgctattgaa gaagtcgtct tgggcgctca ttgatggcag
    15781 taatatcatt gtcaagttct tcagaggtta gtggattaag tgagactcct ttagggacat
    15841 attctctgag gaggccattg aagttctcgt ttgttcctct ctcatgtgaa gaatagggat
    15901 gtgcaaagta aacgtcaaca gcttctaagt ctgagagtaa actaaactca gaaccattat
    15961 ccgctgtgat ggatgcaata ggatactgac tgatgagatg cgtgacagca cggttaatgg
    16021 tttgggactg cttgtcttct agcttaactc ctagtgcata gcgtgtctgg cgctctacca
    16081 aagtcaacat aacagcttca cttttggttt tcttgccgag aaccaaatca atctcccaat
    16141 gcccaaattc agaacgatca ttaatatatt ctggacgttc ttcgatagat ttacctaaag
    16201 tcttcttatt cgtcttcatg actttcttag aacgttttct gatactaacc accttaggca
    16261 aatcgattgg tttaatagac acgttgccca ctatcagcga aataggcgtt gaagaaggtt
    16321 tgttttccat tcttatcctt tacctgatct actgaaccac gttttatttc tcggcagatt
    16381 gtagaacagt gacaccccag aagtcgagca atctcaacgg gtttctttcc cattttaaga
    16441 taagcagcaa tttcaccccg ttctgtggct gaaagatgag aataggatga ctttctggta
    16501 gaattaatat tagacatgtt catctgcttt ccatactgaa ttggggaatt ctagtatatc
    16561 agatgaacat gtcttttttg ttgcacttca ttttacaacg cgggatataa tgttattttc
    16621 tagttttttc aaaataaata ttgacagttt tagataattt ttgttaaaat gatgtggtta
    16681 aggtctcata gctcagctgg atagagcatt cgccttctaa gcgaacggtc gcaggttcga
    16741 atcctgctgg gatcaaagat aaaaaagcac tgttttagtg cttttttttg tatttacctt
    16801 agtgtattga aaagatagga tttagtacgt ctttttttta tatttgcttt taattatacc
    16861 gaactattat ctaataaagt ggtaagagtt agttattcca gttcacactc tcttacttat
    16921 gataaggact gccttgtgta atcataaaag cacgataaat ttgctcagta aggactagac
    16981 gcattaactg atgaggtaag gttaacaatc caaaactcat tagcatatta gctctttttt
    17041 taataattga atctaatcca agactcccac caataataaa cgtgatagtt gaatatccct
    17101 taacagtaac ccctgatatt aattcactaa atgtctctga aggaaactgt tttccttcaa
    17161 tagctaatgc aattacaaaa tcacgttctc caattttttt atggattcgc tgagcttctt
    17221 tactcataat caattgatta tcagcaaaac ttgctttatc tggtgttctt tcatcagtta
    17281 actcaatcat ttcgaattga caaaaacggg aaagtctttt ttgatattct gaaataccat
    17341 ctttgaggta tctttctttt agttttccaa cacaaattag tttcactttc atagcttaat
    17401 tgtatcacaa gaacattact ttttacacaa tttatccaca agttattttt cttcaactac
    17461 taataaaaac ctttgtacaa aggtctttat tagtaaaaag aaaagtaatc cacagcctgt
    17521 ggattacttt tctttttttt atttttaagg tataattaag caaagttcta taagctatgg
    17581 acaaataatt cggaggacaa aacatgccaa gtatgaaaca tatcttaaaa tccttaagta
    17641 ttttactagt tggattttta ggaggattaa tagcaattat tacattcaat aatctctacc
    17701 cacattctcc ttcaaaaata aattcaggta aggcaacaac tagtaatatg gtttttaaca
    17761 acacaaccaa tactactaaa gctgtcaaag ctgttcaaaa tgcagttgta tcagttatta
    17821 attatcaaga taacccttct tcatcccttt ctaaccctta tacaaaactc tttggagaag
    17881 ggcgttcaaa agagaataag gatgctgaat tatctatttt tagtgaagga tctggggtca
    17941 tttatcgaaa agatggcaac tccgcttacg ttgttactaa taaccatgtt atcgacggag
    18001 ctaaacggat tgaaattctt atggcagacg gatctaaagt tgttggtgaa ttagttggag
    18061 ctgatactta ttcggattta gctgttgtta agatctcttc agataagata aaaacagtag
    18121 ctgaatttgc agactctaca aaactaaatg ttggagaagt tgctattgct atcggcagcc
    18181 cactaggaac acaatacgct aattctgtta ctcaaggaat cgtctctagt ttaagtcgta
    18241 ctgtaacttt aaaaaacgag aatggtgaga ctgtctcaac aaatgctatt cagacagatg
    18301 ctgctattaa ccctggaaac tctggtggac cactaattaa tattgagggg caagtaatcg
    18361 gaattaattc aagtaaaatt tcttctaccc caactggtaa caacggtaat agtggtgctg
    18421 ttgaaggaat tggttttgct atcccatcta ctgacgttat taaaattatt aaacaactag
    18481 aaactaatgg tgaagttatt agacctgctc ttggaatatc catggtcaat ttaaatgact
    18541 tatccacaaa tgctcttagc caaattaata ttccaactag tgtaactggt ggtattgtag
    18601 tagcagaagt taaggaagga atgccggcat ctggcaaact tgctcagtac gatgtgatta
    18661 cagaaattga tggcaaaaca gttaattcaa ttagtgattt acaaagtagt ctatacggac
    18721 acgatattaa tgatactatt aaagtaactt tttatagagg aactacaaag aaaaaagcag
    18781 atatcaaatt aacaaaaact actcaagatt tgactaaaac gcagtaaaca agctacctaa
    18841 atactattac attttatcac ataaaacagt ccaaaggact gttttatgtt tcttattcta
    18901 tccaggaact cccttatgac aaaagaatta ttgatagacc taccaattga agatattgtt
    18961 acaaatccct atcagccaag gatacaattt aatcaaagag aactccaaga cctagcaact
    19021 tctattaaat caaacggcct cattcaacct attattgttc gaaaatctga catttttggc
    19081 tatgagttag ttgctggaga acgacgactt aaagcttcaa aaatggctgg tctaaaaaaa
    19141 gttccagcta tcatcaagaa gatctctaca ctcgagagca tgcaacaagc tatagttgaa
    19201 aatttacaac gttctaacct taacgctatc gaagaagcta aagcctatca gttattggtt
    19261 gaaaaaaaac acatgactca cgatgagatt gctaaatata tgggaaaatc aagaccttat
    19321 attagcaata ccttacgtct gttacaactc ccagcaccta tcattaaagc aattgaagaa
    19381 ggaaaaatta gtgcgggaca cgcgcgtgct cttttaactt tgagtgatga taagcaacaa
    19441 ctgtacctca ctcataaaat acaaaatgaa ggcctaagtg ttaggcaaat tgagcaactg
    19501 gttacttcta ctccaagttc gaagctatct aaaaaaacta aaaatatttt tgccacttct
    19561 ttagagaaac aattggctaa atcattggga ctctctgtca atatgaagct gacagcaaac
    19621 catagtgggt accttcagat atctttttcc aatgatgatg aattaaacag aattatcaac
    19681 aagctaaagt agcttgttga tattctgttt tttctttttt agttttccac atgaaaaata
    19741 gttgaaaaca atagcagtgt caccttaaaa tagcttttcc acaggttgtg gagaactcaa
    19801 gttaacagtg ttaatttatt ttccacagat tgtggaaaaa ctaactatta tccattgttc
    19861 tgtggaaaac tagaatagtt tatggtagaa tagttctaga attatccaca agaaggaacc
    19921 tagtatgact gaaaatgaac aaattttttg gaacagggtc ttggaattag ctcagagtca
    19981 attaaaacag gcaacttatg aattttttgt tcatgatgcc cgtctattaa aggtcgataa
    20041 gcatattgca actatttact tagatcaaat gaaagaactc ttttgggaaa aaaatcttaa
    20101 agatgttatt cttactgctg gttttgaagt ttataacgct caaatttctg ttgactatgt
    20161 tttcgaagaa gacctaatga ttgagcaaaa tcagaccaaa atcaatcaaa aacctaagca
    20221 gcaagcctta aattctttgc ctactgttac ttcagattta aactcgaaat atagttttga
    20281 aaactttatt caaggagatg aaaatcgttg ggctgttgct gcttcaatag cagtagctaa
    20341 tactcctgga actacctata atcctttgtt tatttggggt ggccctgggc ttgggaaaac
    20401 ccatttatta aatgctattg gtaattctgt actattagaa aatccaaatg ctcgaattaa
    20461 atatatcaca gctgaaaact ttattaatga gtttgttatc catattcgcc ttgataccat
    20521 ggatgaattg aaagaaaaat ttcgtaattt agatttactc cttattgatg atatccaatc
    20581 tttagctaaa aaaacgctct ctggaacaca agaagagttc tttaatactt ttaatgcact
    20641 tcataataat aacaaacaaa ttgtcctaac aagcgaccgt acaccagatc atctcaatga
    20701 tttagaagat cgattagtta ctcgttttaa atggggatta acagtcaata tcacacctcc
    20761 tgattttgaa acacgagtgg ctattttgac aaataaaatt caagaatata actttatttt
    20821 tcctcaagat accattgagt atttggctgg tcaatttgat tctaatgtca gagatttaga
    20881 aggtgcctta aaagatatta gtctggttgc taatttcaaa caaattgaca cgattactgt
    20941 tgacattgct gccgaagcta ttcgcgccag aaagcaagat ggacctaaaa tgacagttat
    21001 tcccatcgaa gaaattcaag cgcaagttgg aaaattttac ggtgttaccg tcaaagaaat
    21061 taaagctact aaacgaacac aaaatattgt tttagcaaga caagtagcta tgtttttagc
    21121 acgtgaaatg acagataaca gtcttcctaa aattggaaaa gaatttggtg gcagagacca
    21181 ttcaacagta ctccatgcct ataataaaat caaaaacatg atcagccagg acgaaagcct
    21241 taggatcgaa attgaaacca taaaaaacaa aattaaataa catgtggaaa agaatatctt
    21301 ttatgaaata gttatccaca agttgtgaac aaccatttag tcttggattc tctcgtttat
    21361 ttagagttat ccactatata cacaagacct actactacta cttattatta tacttattaa
    21421 ataaaggagt tctcatgatt caattttcaa ttaatcgcac attatttatt catgctttaa
    21481 atgcaactaa acgtgctatt agcactaaaa atgccattcc tattctttca tcaataaaaa
    21541 ttgaagtcac ttctacagga gtaactttaa cagggtctaa cggtcaaata tcaattgaaa
    21601 acactattcc tgtaagtaat gaaaatgctg gtttgctaat tacctctcca ggagctattt
    21661 tattagaagc tagttttttt attaatatta tttcaagttt gccagatatt agtataaatg
    21721 ttaaagaaat tgaacaacac caagttgttt taaccagtgg taaatcagag attaccttaa
    21781 aaggaaaaga tgttgaccag tatcctcgtc tacaagaagt atcaacagaa aatcctttga
    21841 ttttaaaaac aaaattattg aagtctatta ttgctgaaac agcttttgca gccagtttac
    21901 aagaaagtcg tcctatttta acaggagttc atattgtatt aagcaatcat aaagatttta
    21961 aagcagtagc gactgactct catcgtatga gccaacgttt aatcactttg gacaatactt
    22021 cagcagattt tgatgtggtt attccaagta aatctttgag agaattttca gcagtattta
    22081 cagatgatat tgagaccgtt gaggtatttt tctcaccaag ccaaatctta ttcagaagtg
    22141 aacacatttc tttttataca cgcctcttag aaggaaatta tcccgataca gatcgtttat
    22201 taatgacaga atttgagacg gaggttgttt tcaataccca atcccttcgc cacgctatgg
    22261 aacgtgcctt cttgatttct aatgctactc aaaatggtac tgttaagctt gagattactc
    22321 aaaatcatat ttcagctcat gttaactcac ctgaggttgg taaggtaaac gaggatttag
    22381 atattgttag tcagtctggt agtgatttaa ctatcagctt caatccaact taccttattg
    22441 agtctttaaa agctattaaa agtgaaacag taaaaattca tttcttatca ccagttcgac
    22501 cattcaccct aacaccaggc gatgaggaag aaagttttat ccaattaatt acaccagtac
    22561 gaacaaacta agtaagaaaa agctcccttt taggagtttt tttgttatta taaatattaa
    22621 cgataatata agtggagaaa agggaatgta tcaaattgga tcatttgttg aaatgaaaaa
    22681 acctcatgct tgtgtaatta aagaaactgg taaaaaggct aatcaatgga aggtactgag
    22741 agtaggagct gatattaaaa ttcagtgtac taactgtcag catgtgatta tgatgagtcg
    22801 ttatgatttt gagcgaaaat taaaaaaagt actgcaacca tgaaagtcct tttaaataaa
    22861 taattctagc tatatttgca accaatactt tcctaaaaaa ttgctagtat gccgttggaa
    22921 aattagctat tctaatgtta tcgaaagaag aaagatggcc attgacaatg acgaaagttg
    22981 tagcacagtt acttagtttc tcggcaaact atatcaaaat gagaataata caccaaactt
    23041 tgataattta aatgaaggtg aaagagtggc ataatgataa gcaaatctga aattttcttc
    23101 ttattcatac cgctttttct tctatttttt ggtataataa tcttgattga aatttgaatg
    23161 gagattcgct aaatggcttt aacagcaggt attgtaggct taccaaatgt tggtaaatca
    23221 accttattta acgcaattac aaaagcagga gcagaagctg ctaattatcc ttttgcgact
    23281 attgatccca atgttggtat ggtagaggtt ccagatgagc gtctgcaaaa attgacagaa
    23341 ttgattacac ctaaaaaaac agttccgaca acctttgaat ttactgatat tgcaggtatc
    23401 gttaaaggtg cttctagagg ggaaggtcta ggaaataaat ttttagctaa tattcgtgaa
    23461 gtcgatgcta ttgttcatgt ggtacgtgct tttgatgatg aaaatgtcat gcgtgaacaa
    23521 ggtcgtgagg atgctttcgt tgatcctata gcagatattg acactattaa tcttgaatta
    23581 atcttagctg atttagagtc aatcaataaa cgttatgcgc gtgttgaaaa aatggcacga
    23641 actcaaaaag ataaagaatc agtagcagag tttaatgttt tgcaaaagat taaacctgtt
    23701 ttggaagatg ggaaatcagc taggacaatt gagtttacag aagatgaagc aaaagttgtt
    23761 aaaggtctct ttttattaac aactaaacct gttttatatg tagctaatgt cgatgaagat
    23821 aaagttgcta atccagatgg tattgattat gtcaaacaaa ttcgtgactt tgcagctact
    23881 gaaaatgctg aagtagttgt tatctcagcg cgtgcagaag aagaaatttc agagcttgac
    23941 gatgaggata aagaagaatt tttggaagct atcggtctta ctgaatcagg cgttgataaa
    24001 ttaaccagag cagcttatca tctcttaggc cttggaacct attttacagc aggtgaaaaa
    24061 gaggttcgtg cttggacgtt taagcgtggt ataaaagctc cacaagctgc tggtattatc
    24121 cattcagatt ttgaaagagg ttttattcgt gcagtaacca tgtcttatga tgatctaatg
    24181 acctacggtt cagaaaaagc cgtcaaagaa gctggacgct tgcgtgaaga aggaaaagaa
    24241 tatgttgtcc aagatgggga catcatggaa ttcagattta atgtgtaatt atattaaaac
    24301 aatatcagaa ggttggaaga acattccagc ccttttggca ttttagaaag agaaaatatg
    24361 gtaaaaatga ttgttggtct gggaaatcca ggctctaaat atgaaaaaac aaagcacaat
    24421 attggtttta tggctattga caatattgtc aagaaccttg acgttacctt tacagatgat
    24481 aaaaatttta aagcacagat aggaagtact tttattaatc atgaaaaagt ttactttgtg
    24541 aaacctacta cttttatgaa taatagcggc atagcagtaa aagcattact aacctactat
    24601 aatattgaca taacagattt aattgttatc tatgatgatt tagacatgga agtcagtaaa
    24661 ttacgtttac gtagtaaggg ttcagcagga ggacataatg gcattaagtc aatcattgcc
    24721 cacattggaa ctcaggaatt taaccgaatc aaagttggta ttggacgacc tttaaaaggt
    24781 atgactgtta ttaaccatgt gatgggccaa ttcaataccg aagataatat tgctatttcg
    24841 ttaactcttg acagagttgt caatgctgtc aagttttatt tacaagaaaa tgattttgaa
    24901 aaaacaatgc agaaatttaa tggataatca tgaatatttt agaattattt agtcagaata
    24961 agaaagtcca atcctggcac tctggattaa ccaccttagg aagacaactg gtaatggggt
    25021 tatcgggttc aagtaaagca ttggctatag cttccgctta tttagatgat caaaaaaaaa
    25081 tagttgtggt tacatcaact caaaatgagg ttgaaaaatt agccagcgat ttatctagtt
    25141 tacttgatga agaacttgtt ttccaatttt ttgcagacga tgtggctgca gcggaattta
    25201 tctttgcgtc aatggataaa gctctatcaa gaatagaaac cctgcaattt ttaatgaatc
    25261 ctaaatctca gggcgtttta attgttagtt tatcaggctt aagaacttta ttgccaaacc
    25321 cagatgtttt tacaaagagt cagattcaac taacagttgg agaagattat gatagtgata
    25381 ctcttactaa acaactgatg acaattggat atcagaaggt ctcacaggtt attagtccgg
    25441 gagaatttag ccgtcgaggg gatattttag atatctatga gattacacaa gaattgcctt
    25501 atcgattgga attttttggt gatgatattg atagtattag gcaatttcat ccagaaactc
    25561 aaaaatcttt tgaacaacta gaaggtattt ttattaatcc agcaagtgat cttatttttg
    25621 aggctagtga ttttcaacgt ggcattgagc aattagaaaa ggctctacaa acagcacaag
    25681 atgataaaaa atcttattta gaagatgtat tagctgtttc aaaaaacggt tttaaacata
    25741 aggatatccg taaatttcaa tcattatttt atgaaaaaga gtggtcatta ttagattata
    25801 ttcctaaggg aacgccaatc ttttttgatg attttcaaaa actagttgat aaaaatgcaa
    25861 gatttgattt agagattgct aatctcttga cagaagattt acagcaagga aaggctcttt
    25921 ccaatcttaa ctactttaca gataattatc gagagcttag gcactataag ccagcgacct
    25981 tcttttcaaa ttttcataag ggacttggaa atatcaaatt tgatcagatg catcagctaa
    26041 ctcagtatgc catgcaggaa ttttttaatc aatttccttt gttgattgat gagattaaac
    26101 ggtatcaaaa aaatcaaaca acggttattg tacaggtaga gtctcagtat gcttacaaac
    26161 gacttgaaaa atcttttcaa gattaccaat ttcgccttcc tttagtgagt gctaatcaaa
    26221 ttgtttcacg tgaatcacaa attgtaattg gagctatctc cagtggtttt tattttgctg
    26281 atgaaaagtt agcgttaatc acagagcgtg aaatttatca taaaaagatc aaacgacgcg
    26341 ctagacgatc taatattagc aatgctgagc gtttgaaaga ttacaatgag ttagcagtag
    26401 gtgattacgt ggttcataat gtccatggta tcggtcgctt tcttggaatt gaaacgattc
    26461 agattcaggg aatccatcga gattatgtta ctattcaata tcaaaattca gaccgtattt
    26521 ctcttccaat tgaccaaatt ggtagcttat caaagtacgt ttctgctgat ggaaaagaac
    26581 ctaaaattaa taaactcaat gatggtcgtt tccaaaagac aaagcaaaag gtcgctagac
    26641 aagtagagga tattgctgat gaccttctaa aattatatgc tgaaagaagt cagcaaaaag
    26701 gattttcatt ttcaccagat gatgacttgc agcgcgcttt tgatgatgat tttgcttttg
    26761 tagaaacaga agatcaactt aggtctataa aggaaattaa agctgatatg gagagcatgc
    26821 agcctatgga tcgtctttta gtaggcgatg taggatttgg taagacagaa gtagctatga
    26881 gggcagcctt taaagcggtg aatgatcaca aacaagtagc tgtcttagtt ccaaccacag
    26941 tcttggccca gcagcattat gaaaacttca aagcacgctt tgaaaattac cctgttgagg
    27001 ttgacgtctt aagtcgtttc cgtagtaaaa aagagcaagc tgaaacacta gaacgtgtac
    27061 gaaaaggtca aattgacatt attatcggaa cccatcgact cctatcaaaa gatgtggtct
    27121 tttctgattt aggattgatt gtgattgatg aggaacaacg gtttggtgtt aagcataaag
    27181 aaactttaaa ggaattaaaa actaaggttg acgtcttaac cttaacagct actccgattc
    27241 ctagaacctt acacatgtct atgttaggta tccgagattt atcggttatt gagaccccac
    27301 caaccaatcg ttatcctgtt caaacctatg ttttggaaaa taatccaggt ctcgttagag
    27361 aagctatcat tcgtgaaatg gatcgtggag gacaaatttt ttacgtttac aataaagttg
    27421 acactattga aaagaaagtt tcagagctac aagaattagt cccagaagct tctataggtt
    27481 ttgttcatgg gcaaatgagt gaaattcaac ttgaaaatac cttgattgac tttataaatg
    27541 gtgattatga tgtccttgtg gctacaacaa tcatcgaaac aggagttgac atttctaatg
    27601 taaacacttt gtttattgag aatgctgatc atatgggatt gtcaacttta tatcaactac
    27661 gagggcgcgt cggaagaagt aatcgtattg cttatgctta cctgatgtat cgtcctgata
    27721 aggtcctaac agaggtttct gaaaagcgtt tagaggctat taaaggcttt actgaattag
    27781 gttcaggctt caagattgct atgcgagatt tgtctatacg aggagcaggt aatattttag
    27841 gggcttctca gagtggcttt attgattcgg tcggttttga aatgtattct cagttattgg
    27901 aacaggctat tgctagcaag caaggaaaaa cgactgttcg ccaaaaaggt aatactgaaa
    27961 tcaatcttca gattgacgcc tatttgccag atgattacat atcagatgag cgtcaaaaaa
    28021 ttgacattta caagcgtatt cgagaaattc aatcaagaga agattatctc aatttgcagg
    28081 atgagctgat agatcgtttt ggagagtatc ctgatcaagt tgcctatttg ttagagatag
    28141 ctctgctaaa acattatatg gacaatgcct ttgcggaatt agttgaacgc aaaaataatc
    28201 aggtcattgt tcgatttgaa gtaacttctt taacttattt cttgactcag gattatttcg
    28261 aagccttatc gaaaacccat cttaaagcta aaattagtga acatcagggg aaaatcgata
    28321 tcgtctttga cgttcgccat caaaaagatt atagaatttt agaagaattg atgttatttg
    28381 gagaaaggct tagtgagata aaaatcagaa aaaacaattc agtttttaaa taataatttg
    28441 aaacaacttt tagactgaat agtattaat
//
LOCUS       DAUNLR010000021        27954 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUNLR010000021 DAUNLR010000000
VERSION     DAUNLR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27954
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.021"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(455..889)
                     /locus_tag="VLL59_000907"
     CDS             complement(455..889)
                     /locus_tag="VLL59_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509038.1"
                     /translation="MKQQSYQLLRFVYLLVALFAAMLLIARPVMADEEANDPADAAYY
                     KGKNDGEKAGKKASESAKWTDLTPPDPTTIPEPPSGIKDSTNQEHYKEGYKDGYRDGY
                     NEGWKSQHLVLTPVKVIWDLISYWLKQFFPNNQSSTAAQSMS"
     gene            complement(1144..2859)
                     /gene="slo"
                     /locus_tag="VLL59_000908"
     CDS             complement(1144..2859)
                     /gene="slo"
                     /locus_tag="VLL59_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HER6509039.1"
                     /translation="MSNKKIFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTIEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRT
                     EYVETTSTEYTSGKINLSHRGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(2883..3368)
                     /locus_tag="VLL59_000909"
     CDS             complement(2883..3368)
                     /locus_tag="VLL59_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HER6509040.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMEHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(3373..4728)
                     /gene="nga"
                     /locus_tag="VLL59_000910"
     CDS             complement(3373..4728)
                     /gene="nga"
                     /locus_tag="VLL59_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HER6509041.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFASPM
                     HIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFHKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNIERDIFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAIQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            complement(5099..5638)
                     /gene="nusG"
                     /locus_tag="VLL59_000911"
     CDS             complement(5099..5638)
                     /gene="nusG"
                     /locus_tag="VLL59_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HER6509042.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(5811..6854)
                     /locus_tag="VLL59_000912"
     CDS             complement(5811..6854)
                     /locus_tag="VLL59_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HER6509043.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSAKQITDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYASSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAK
                     KAIIEGTITVPEN"
     gene            complement(7181..8473)
                     /locus_tag="VLL59_000913"
     CDS             complement(7181..8473)
                     /locus_tag="VLL59_000913"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HER6509044.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGKRIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGERIDHYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            8911..9789
                     /locus_tag="VLL59_000914"
     CDS             8911..9789
                     /locus_tag="VLL59_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509045.1"
                     /translation="MIRKYDHTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDIFTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            9802..11064
                     /locus_tag="VLL59_000915"
     CDS             9802..11064
                     /locus_tag="VLL59_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HER6509046.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILTEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTHA"
     gene            complement(11184..11810)
                     /locus_tag="VLL59_000916"
     CDS             complement(11184..11810)
                     /locus_tag="VLL59_000916"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HER6509047.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFADL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLEETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(11855..13270)
                     /locus_tag="VLL59_000917"
     CDS             complement(11855..13270)
                     /locus_tag="VLL59_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HER6509048.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(13271..15046)
                     /locus_tag="VLL59_000918"
     CDS             complement(13271..15046)
                     /locus_tag="VLL59_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HER6509049.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEAGKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            complement(15247..15567)
                     /locus_tag="VLL59_000919"
     CDS             complement(15247..15567)
                     /locus_tag="VLL59_000919"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HER6509050.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALAHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(15564..16562)
                     /locus_tag="VLL59_000920"
     CDS             complement(15564..16562)
                     /locus_tag="VLL59_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HER6509051.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            complement(16578..17162)
                     /locus_tag="VLL59_000921"
     CDS             complement(16578..17162)
                     /locus_tag="VLL59_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HER6509052.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(17231..17710)
                     /locus_tag="VLL59_000922"
     CDS             complement(17231..17710)
                     /locus_tag="VLL59_000922"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HER6509053.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(17712..19712)
                     /locus_tag="VLL59_000923"
     CDS             complement(17712..19712)
                     /locus_tag="VLL59_000923"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HER6509054.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEESHRQQAAQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFYFLSARVGTIPSTANDHFYHQLKQHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVAIWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(19702..20022)
                     /locus_tag="VLL59_000924"
     CDS             complement(19702..20022)
                     /locus_tag="VLL59_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509055.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(20476..21495)
                     /locus_tag="VLL59_000925"
     CDS             complement(20476..21495)
                     /locus_tag="VLL59_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HER6509056.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(21532..21897)
                     /locus_tag="VLL59_000926"
     CDS             complement(21532..21897)
                     /locus_tag="VLL59_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HER6509057.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            22071..22751
                     /locus_tag="VLL59_000927"
     CDS             22071..22751
                     /locus_tag="VLL59_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HER6509058.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(22873..23520)
                     /locus_tag="VLL59_000928"
     CDS             complement(22873..23520)
                     /locus_tag="VLL59_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HER6509059.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(23523..24182)
                     /locus_tag="VLL59_000929"
     CDS             complement(23523..24182)
                     /locus_tag="VLL59_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HER6509060.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(24194..25378)
                     /locus_tag="VLL59_000930"
     CDS             complement(24194..25378)
                     /locus_tag="VLL59_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HER6509061.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            25499..26410
                     /locus_tag="VLL59_000931"
     CDS             25499..26410
                     /locus_tag="VLL59_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HER6509062.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVRLTSVGERFFENAKVVIASHEQLMADLRSESQKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEVKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKISHLKHYIKHTILDYFTNQRF"
     gene            complement(26478..27877)
                     /locus_tag="VLL59_000932"
                     /pseudo
     CDS             complement(26478..27877)
                     /locus_tag="VLL59_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
BASE COUNT         8446 a         5995 c         4906 g         8607 t
ORIGIN      
        1 gcaactgctg ctgtcgtaag ccttagcctt gcaacaccag aaaaccaaac tgtttcagca
       61 aatgagacag ccgtttcaac aatctgtacc gatggaaatg gttgttgcaa cggttctttc
      121 tttggatact gtggacctat cagctggtta ttttaccata caaaatattt attaggttat
      181 cctaatccaa atacaattac aactacggat acagtcacaa aatagtgaga ctgtgattat
      241 aaaaaagccc aagcctgctt aggcagtcct gggctttttt gctgtcctaa agtcagggta
      301 ttgccacaac ttcaaaccca aagacaatta aaccgcaccc caacaattag acataggcta
      361 tgtccccaga atcctggaca catatcacta aagcctaatg attaaggtgc ggtttaagat
      421 gtggtagcaa ggaactgttt taaattcgtt tttattatga catgctttgt gctgcggtac
      481 ttgactggtt attggggaag aattgcttta gccaataaga gatcaaatcc catataacct
      541 tgaccggagt caagacgaga tgctgagatt tccagccttc attataacca tctctgtatc
      601 catctttata cccttcttta taatgctctt gattagtaga atctttaata ccactaggtg
      661 gttctggaat tgttgttgga tctggtgggg tcaaatcagt ccactttgct gattcactag
      721 cttttttccc tgctttctct ccatcgtttt tccctttata atacgctgca tcagctgggt
      781 cattagcctc ctcatccgcc ataacaggtc ttgctataag caacatagca gcaaatagag
      841 ccaccaagag gtagacgaag cgtagaagct ggtaagattg ttgtttcatg acaatagtta
      901 tctctccctt ttatgttatg ctttgcttgt taaaaagcag cttgttagta ttatagatta
      961 gaagcagctt agcttcaagg tcacgatgtg agaaaagaat aactttttga ttagtatatc
     1021 aaaaaagctt gtctatgaga taccttcata gacaagcttt tttctgtatt tgtgagagga
     1081 gtaggcacaa ggcctcaaga gataagcagc atcaaggtgc ttgacgaacc tcttgaacca
     1141 gtcctactta taagtaatcg aaccatatgg gctcaaggtt gatcctgaga tgttgacatt
     1201 gatttcttta gacagtttca catctctttc gtcgatcact tttcgccacc attcccaagc
     1261 taagccggtg cactctctag ccatgatacg gatatttcgt gaattagctc ctagtgggat
     1321 aactgtgcta aatggtgatg tcttactata ccagttgttg tcccaacgtc gttttgtaat
     1381 cacttctttt cctttgtcat cataattgat ttcatcccaa aggatttcat attgagcaac
     1441 atacgcacct cgatgagaca ggttaatttt tccactagtg tactcggtag atgttgtttc
     1501 aacgtattca gttctgttat tgacacccgc aattttatta tttttaagga aaacactggt
     1561 gtatgaaata ggataagctg ggttttttct actgaaggta gcattgtctt tgataacgtt
     1621 tctaataaca tcaaagtctt ttgtgactac cttattgtgc tctgcagcat ctcctcctaa
     1681 aacgacagct gtaaatgagc tattttctaa gatatcagag tattttccat tcgttttaac
     1741 atctgttcct tttagagctg cactaaaggc cgcttcaaca tcattacttt tagaacttgt
     1801 ttctagtttg acaaaaacag ttcgaccata ggctacatta ctaacaaaga gtggcggagc
     1861 ttcattgctg acaccttttc gttgcaactc tttaaaggtc actgatttat caaacacatc
     1921 cgcaggatta ttaggaaggt ttgctgatac ggtgtaaaaa atttgcttgt atgctgcaat
     1981 catcaccttc ttttcacctt ttgaaatcga cttgaaatca atgcctaaag taccatctaa
     2041 gattttgcta ttaacattta gagctgcttc aatctgtgac ttagaatata ccattgattc
     2101 agtatattgt gttctggcag gaagcgtatt accaccagaa taattatcat gccattggtt
     2161 aacaagatta tcaatagctg ttgaaacatt ggcataggta gggtcattga cctcaaccgt
     2221 tgctttgtct cccatacctg gtaaatcaat atggattttt tgtgggtttc gcttggtgac
     2281 taccgcgtct ggtttgtttt cggtaaaacc tttatcagcc agctgaaggg ctgctggata
     2341 ggtcatatca gtgacagagt caatgatgga aatatcgact ggtgtagtgt tgatattttt
     2401 tttctttctt tcaatgacaa taaatttatc agctttctta acgccttctt taggaacaaa
     2461 attttcaatg gtttcaccat ttttagcaag tacttcaagc tcattataat ttagtgaata
     2521 aatcttgtca ttgatttctt cagtgtgatc ttcttcgctc ttttttttgt cttctgactt
     2581 tttttcttct ttttctgcag attctagtgg catttctttg ggagcaagct taatcatatc
     2641 gttagagtta agcatatcat ccattttctg acctgctttt tcgatagtta gctcactact
     2701 ttctggtttt ggttgctcat ttgtcgttgt ggtttctgta ctagcagtgt tttgtttgtt
     2761 cgattcagca ttagcagtaa caagattacc aatgataaga gctgccgtta gtagcccagc
     2821 gacgcgactg tattttttaa atattttttt attagacatg tccttcatac ctttttatca
     2881 ttctaaaatg tttctattgt tctttcgacc atatcaagca tagtatcttg atagtgagca
     2941 aattctccta atttgtaatg ttccatagcc tctctaatat gcgcatcttt taacgctttg
     3001 gttatattag ctagtatgct ttgacggttt aaataaaatg gcaagctttc gtaataattt
     3061 aataacatgt tttcagcgtt tagggtttga accgcttggt aaatgtctaa tgcttgaccg
     3121 ctatttgaca tttctaataa tgcttcttcg atgttagctt tcaattgggt atagcctttt
     3181 atgaaagcag ggtaaacccc atactctaaa ataacttctg gatcagaaat atctcccata
     3241 taagagtctc tcctagtgat acgatactct ttgtcactac ctatcaagta tttttttaaa
     3301 tcattaacag ttacttcttt ttgaaacatt ttttggtaat gttctaaacc ctttggcacc
     3361 ttatacatat tgttacttcc tatcttgcat tctatcttgc attttcttaa ttttgaagcg
     3421 accagttact tttttatggt caccatttgg agcaatgatg gtaggatcaa taatttcaaa
     3481 atagcctttg gcatcaatct ctgctaagac agctttagat tttagatctt taacactaat
     3541 cgatgggaaa attaattcac tttctgaatt ttcaatgtgt tttcctgacc acgtttggca
     3601 accaggaatg ttgagcgaat ttgctccagg agtatctccg ctagctgttc ggatatagcc
     3661 tagcttatca atgttttttg ttagttcaga atcgtactca tattgataaa ccccatcact
     3721 atattttccg ctatcgacac cttttatatt ttcaatttgg tcagctgatt ttaacttacc
     3781 ttgatcagta aagagcaatg ccatatcttc agcaaaactt gtcacaaaaa gaccgttttc
     3841 ttgtcgacca atcgttgact ttcttttagc atcgtcaaaa gctaacatca aatctttttt
     3901 gcttgtaacg tgggaagctc cgctttcttt gtagacttgt tttagttttt caacaaactc
     3961 ttttttgtag tggtatttgc ggctaacata catccggtaa tactcagcac gtgacgcaac
     4021 agcagacatc tgaatagctt tatcagcata cttgtcggca gtttcaataa actcatctgc
     4081 ttgtttatct gttacccatt tatctttaat ttctttaaac tttttttcaa aaatatcgcg
     4141 ttctatattg ccaaaagtga cctctgacaa ggctaaaata tccttgtttt gtccctgatg
     4201 gacctctgtt acctcaatat caatacgatc aacatctaat tttttatcaa tctcaatgtg
     4261 atgcggtttt ttagtgtagg tgtcgcctaa ttcaattttg tgaaagagga ccaatttatt
     4321 cccgttatag tatttaacat cagcctttgc aattctattt ttcttgtagt aattctcctt
     4381 gctagatgta tctccattaa caattaaaat tctcccaata tgcatcgggg acgcaaactt
     4441 gtaggaaagt acttcaccaa caccaccacc aggtgaattt tcctcccaga cagtactcat
     4501 tgagccgtct aatgtgtgca tgacatgatt gtcttcttta gaggaagttg cgttagcttc
     4561 cataactttg gtcgtttcat atttgacatc gcttttttta ttttctttgc cactaacagc
     4621 gtacgttgtg ctattagcta ataaactgct acccattgct ccagccaaag caatagcaac
     4681 acttgtcttt gcgacaatat gagctaatgt tacttttttg tttctcatgt aaaccacctt
     4741 atattatttt taagtaaact atacattagc aaatagtttt tgtcaatgcg atttattaac
     4801 atcgttttag acttttctat caaaaaaatg aacacaaaaa aacaagtagc caactgttac
     4861 aagtttcaag gggatatttc catcttatta tcacagaacc ttcacatctg ttctatttaa
     4921 accagattaa aagtactagt taaatatttg atagtagcac cgttatcagt aatagatctg
     4981 ttaattatct ctgattacaa tgatgttaac gatagtcata cctttgtttg tacacacgct
     5041 tcacttccaa ctaaaaaagg tctgatggta atacttatac catcagacct ttgagagcct
     5101 atagttctgc aatttgataa agttcaactt ctgctactgt ttcagagcca aacatgttga
     5161 gcatcagttt cactttgttg ttttcgattt ctaccacacg accttcttgt cccataaagg
     5221 caccgtctat gatctgaacc acatcgcctt ctttgatatt ggtatcaaag acatcaatgg
     5281 tttgccccat agacaacaag atagcacgga tttcttcttc aagaagtggt gttggttttg
     5341 atcggttccc gtgtgatccc acaaaacctg taacgtttgg tgtgttacgc acaacaaacc
     5401 aagcttcatc tgtcatgacc atttcaacca agacataccc tggaaagcga ttttcttcga
     5461 tttctttggt ttgcccattt ttttcaacgt taaccgtttg tgtcggaatt tcgacgcgca
     5521 aaatattgtc caacatgtta taggtttggg cacgttgcaa gaggttttct tttactttgt
     5581 tttcgtagcc tgagtaagtt tggaggacga accagccctt atcaaatgaa tctagcatga
     5641 tgtttccttt cattataaaa aagcccttta tttggctttt gcgctgtttt ctatcacctt
     5701 cattataata aaagacaggg ctgctgtcaa cgtatctgtg gagctacttg acacctttat
     5761 taaaaagtcc aaagtcggtt cgtgacgact ctggacggta ttgtacagtt ttagttttca
     5821 ggaactgtga tggttccttc gataatcgct tttttagcag cctcaatagc ttttttagtg
     5881 tcttgtgtca gagcatccgt tgtaaggcta acaccacctt cttttaaacc aaaagtggtt
     5941 atttgaccac ctgggaattg gccttctgag gtttttacgg ctacttttac taaagctttt
     6001 ccgacttcct tgatacttga ggtcaaaaca aaattagctg acttgccatc ttttgtggtg
     6061 tattttccat cttcactttg gtcacggtca acaccaataa cccaaacctt atcttcttct
     6121 ttacgttttt cgttgataga cttagcttcg ctaaagacac ccgctcctgt gcctcctgct
     6181 gcatgataaa taacatctgc gccttcagcg tattgagcag ctgcaatcgt cttgccttta
     6241 gcagcatctg caaaagagct tgcataagca actcttactt tgatggtatc atctactgat
     6301 ttcacaccag cttcaaaacc tttttcaaag cgcttgacaa catctccttc cataccacct
     6361 acaaaaccaa cttgcttggt ttttgtcgtt ttagctgctg caacaccggc taggtatgcc
     6421 gcttcatggt ctgaaaaggt gatacttgca acattttttt gacctttaat cacatcatcc
     6481 acaattgcaa aatggttgtc aggattgttt gcggctactt tttctacagc gtcatgtaat
     6541 ggaaatccaa tcccaaaaac aagattataa ccattggtta ctgctgactc aaggtttgtg
     6601 gtaaactctg attcattggc tgattggaaa taatcatagc cttttccttt ttcaagttta
     6661 ttttcttttc cccaagcttg caagccttcc caggctgact ggttaaatga cttgtcatca
     6721 atacccgtct gattagtaat catagcgatt tttaatgaat tgtcagttat ttgtttagcg
     6781 gagttattgg tacagcctcc taatgtgaat agggcagtcg aaacaagacc aagtgacatt
     6841 acttttttgt tcatgtgaaa atgaacctcc taaatgttta atcctaaagt gatgtgtcat
     6901 tgttaacgtt ctacttatgc tctagaacga aaagtttagt atatcaaaaa aatcagtttt
     6961 atcctactat ttttgttgaa aaatctcttt ttcaccaaaa tgaccgaacg ataaagtgag
     7021 atcaactggt aaatcccatt atctcctcaa aaatcacctc ttaaggagat aagtcaacga
     7081 caaaactcaa gctactaata atagcatgac taactataca atccaacaag cggtaaaaag
     7141 agctggaaac gctatccaac tctttgtcat actagacacc ttagatagat gcccagaccg
     7201 actcaagaat attggtctgt tcacgtcctg gaccaactga gaaggttgaa atgcgaacgc
     7261 caaccaattc tcccacgcga cgaacgtagt tgcgggcatt ttcaggcagc tcatcaaggc
     7321 tacgaacacc tgtgatgtcc tcttgccagc ctggtaattc ttcatagatt ggtttgcaac
     7381 gtttgagttg ttcaagactt gctgggtagt gatcaatacg ttcaccatct aaatcgtaag
     7441 ccacacaaat cttaaccgta tcaagtcctg aaagaacgtc aatggaattg agggaaaggt
     7501 tagtaatccc tgacacacga cgactatggc gcataacaac tgagtcaaac caaccgacac
     7561 gacgtggacg gccggtcgtt gtcccgtact catgacccac ttcacgaata cgcttaccca
     7621 cttcatcaaa gagttctgta gggaatggcc catcaccgac acggcttgtg taggctttac
     7681 agacaccaac tactttgttg attttacttg ggccaacacc agaaccaatg gttacaccac
     7741 cagcaactgg gtttgaagac gttacaaatg ggtaagttcc ttggtcaata tcaagcataa
     7801 ccccttgagc accttcaaaa agaacacgtt taccggcatc aagtgcatca tttaaaatta
     7861 cagaagtatc tgtcacatat tgcttgattt cttgaccgta agcatagtat tcttcaaaaa
     7921 tagcatcaaa atcaagaggt gtactgtcat acattttttc aaataaacgg tttttctcag
     7981 ctaaattaat gcgtaggcgc tctgcaaaga tatccttatc cagtaaatct gcgatacgga
     8041 taccaactcg agcagcttta tccatataag ctggaccaat ccctttaata gttgttccga
     8101 ttttattgtc accttttgca tcttcttgca gttgatccag ctggatatga taaggtaaaa
     8161 taacatgagc tcggtctgaa atgcgaaggt tatctgtcgt cactccttca tcatgcaggt
     8221 acgccaactc tttgaccaaa gatttggggt tgaccacaac accattacca ataacggaaa
     8281 ttttttgcgg gaagaaaatt cctgatggga tcaagtgaag tttaaacttc ttaccatcaa
     8341 tcacgatcgt atgaccagca ttatcaccac cttgatagcg tgcaattact tctgcatccg
     8401 ctgacaagaa atcagtgatt ttacctttac cttcgtcacc ccactgggta ccaacaacaa
     8461 ctacagatgt catatcattg tcctaacttt ctgaaacact tattctcaat aaaaatcata
     8521 ggcaagctaa ccactgctta aaaaccaaaa agaaggtcag atctgtaaga tcagcaatgt
     8581 agctcttgat atttaaagaa aacaggcagg aatctcacct gctagcatat atcttacaac
     8641 ttattatagc aaaaaatggt tttttctgct agatttctta gcattattaa ggaaaaagag
     8701 aaactctttt tttaaccatg ataaacaatc ctaaaaaaac gaatattata agagaaaagc
     8761 ttttaacctc gtttctccta agctttagca gggttaaacg attctcttaa aacattagct
     8821 cttttctttc agaaatagcg gttttaaggt aaaataatag taagttacct ctatgagata
     8881 gccagtaaaa acatatcgag gaaatatcac atgattagaa agtatgacca cacgagcaca
     8941 aaaaagaaat cactaaactg gatttggcta atcattgctt tttttatgat ttcaagcttt
     9001 ataggtggct cttcttttac tgagtcactt ctagacattt tgcctgccat agccattggt
     9061 ggtacaggtt atgctatttt tcgtgttaga tctcatcaaa agcggctagc aaaggccaag
     9121 attgccaaac aattagaaga tctaaaagca aaaattcagc tagctgatcg taaagttcgg
     9181 ctgttagata cttatctggc agaccatgat gacttccaat ataacgtact tgctcagcaa
     9241 ttattaccac aacttagtga catcaaagca aaagctatta cgttaaaaga ccagttagat
     9301 cccaaaattt atcgtcgtat caccaaaaaa gccaatgacg ttgaaagtga tattaccctt
     9361 caactcgaaa cactgcagat tgccacaact cttaaccctc agcctttgaa aaccccatct
     9421 cctaatctta ttaacaaagc acctgagctc aaaccgtatt atgataatat tcagacagat
     9481 catcaagcta tccttgctaa aatccaagga gctgacaatc aagaagaatt gcttgcgctg
     9541 catgaagcta acatgaggag gtttgaggat atcttcacag gctacttaaa aatcaaagaa
     9601 gagcctaaaa attactataa cgctgctgct cgtttagaac aagccaaaca agctatccaa
     9661 caatttgatg aagatcttga cgaaaccctt cgtcgactca atgaaagtga tcttaaagat
     9721 tttgatatta gccttcgaat catgcaaggt gctactcaaa gacgaacaac gcatcaccaa
     9781 aaagactaaa ggagtccctt tatggcagat tttaattttg acattgacca aattgctgac
     9841 aatgctgttg tcaaaaccga taaaaccacc gatattatct cagacttacc aactgacaca
     9901 aatggccaaa tctctttttt tgagaaacta agtgctgacc aacagacagc tattactgcc
     9961 aaagccccgg cattggtaga taccttttta gcagatcaaa atgcgctact tgattttggt
    10021 cagtctgctg ttgaaggggt caatgcaacg gtcaatcata tcctgaccga acaaaagaag
    10081 ttacagattc ctcaggttga tgatctttta aaatcaacca atcgtgaact caatggtttt
    10141 atcgctaaat acaaggatgc cacacctgtg gaccttgata aaaagccaaa ctttcttcaa
    10201 aaactcttta aacaaagccg tgataccctg caagagtttt attttgattc tcaaaacatt
    10261 gagcaaaaaa tggatagtat ggctgcagcg gttgtcaagc aagaagatac cttagctcgc
    10321 aatattgtct cagcagaatt gttaattgaa gataatacta agtccattga acatttggta
    10381 ggcgtcattg cttttatcga agctagtcaa aaagaagcta gtcagcgcgc tgcggcttta
    10441 caaaaagacc taaaaaccaa agacagtgct acaccagact atcaaataaa agctgatctt
    10501 ttggcaagaa ctaccgaagt catcaacact ctcgaacaac aacacaccga atacttgagt
    10561 cgcctctatg ttgcttgggc gacaactccg caaatgcgta atctagtcaa ggtctcttct
    10621 gatatgcgtc aaaaactagg catgttacgc cgcaatacca ttccaacgat gaaactatct
    10681 attgctcagt taggcatgat gcaacaatcg gttaaatctg gaatgactgc tgatgccatt
    10741 attaatgcta ataatgctgc cctccaaatg ctagcagaaa caagtaaaga agccatccca
    10801 gcattagaac aatcagcaca aaaccctact ttgtctatga aatctgtgac aagtctggca
    10861 gaaagtttag tagcacaaaa taatgggatc attgcggcga ttgatcatgg acgcaaagaa
    10921 cgagcacaac tagaaagtgc tattatcagg tctgccgaaa ccattaacga ttctgtcaaa
    10981 ctacgtgacc aaaatattgt gcaagcactt cttagtgaag gcaaggaaac tcaaaaaaca
    11041 attgataaaa caactcacgc ataagctaaa catcacctgt cacgctactt aaaaagcaag
    11101 ccatcaatta ggttaatccc tttgatgtct tgctttttta ctacttaacg aataatcgcc
    11161 ttgtttgata taacacttat cttttatgat gttattttca taatacgaac aaggctagca
    11221 cgctcggcct cttctaattt caactcaatg tagtgaatcg tctcttccag ttgcgggata
    11281 atagaatact ctaagccatt gacgcgacgt ctagtctttt caatgtcatc agccattagt
    11341 tgacaagttt tttcaacttc agctaaccgt aagagctttt ctaatagttc ttttgtcttt
    11401 tggatagtat tgtccatctc actatttgag ctgaggtaac tataagcaaa ctcaccttgt
    11461 tcttgctctc ttgccgtatt agactggaca tggaatttag gcacattgac actcatgata
    11521 ttttcaatat caatccataa ggtcacttca tggactggaa cagcaaagag ttcttctacc
    11581 attagactat tttcggatgc ttttgccaag acaaactcct tcatattggc agcaagttct
    11641 ttttcgatag tttgacgaag ctcattgttt tcacgaatta aatcagcgaa gcgacgcatc
    11701 aactcatccc gcttgtcctt taataattta tgacctcttg tagctgtctt caagcgattt
    11761 ttcaagttac taagttccat gcgtgttggt ttaacattta atcgtgccat tgatataact
    11821 cctttcgtca aggacttgaa attgcatggt caactcaatc atttgcaaca aaaacctttg
    11881 tcatcgtggt atctgcttta ggcaaataac gatctaacat atcatcttta atgcgtttta
    11941 attcggtacg tggcaaaatc gacaacaatt cccaacccaa gtcaagactt tcttcaatgc
    12001 tacggttggt gtaaaatcct tggttaatgt attcttcttc aaaccggttg gtaaaggcca
    12061 catatagttt atccgtttca gaaagggctg attcaccgag cacaacagcc aattccttag
    12121 cttgttttcc ttgggcatag gctgcaaaga gctgattcat tgtagcagca tggtcttgtc
    12181 gagtcttacc ttcacctgag cctttatctt ttaggcgaga tagcgatggc aagacattaa
    12241 taggcggtct aaaaccattt ttatatagtt cttgcgacaa aataatctga ccttcggtaa
    12301 tataacctgt caaatcgggg atagggtggg taatgtcatc ttctggcatg gttaaaatag
    12361 gaatttgagt cactgaccct tttttcccga tcaagcgacc agcccgttca tataaggtgg
    12421 agagattagt atagagatag ccaggataac ctcgtctgcc tggaacttct ctgcgagcgg
    12481 ctgatacttc tcgtaaggct tcacaataat ttgtcatatc tgtcatgatg actaaaacat
    12541 gcataccttt ttcataagcc aagtattcgg ctgttgtcag agctatacgt ggtgttgcaa
    12601 tgcgttcaat agcagggtca ttagccaaat tgataaataa aacagatcga tcaatggcac
    12661 ccgtttcacg caagtcattc ataaagaatt ctgcctcttc aaaagtaata cccatagctg
    12721 caaacacaac cgcaaagtta tcatcagagt ttagaacagt tgcctgacga gcaatctgtg
    12781 cggccaattc attatgaggt aaccctgagc ccgaaaaaac tggtaacttt tgaccacgaa
    12841 cgagggtatt gaggtgatca atagctgaga tacctgtctg gataaattcg tctgggtaat
    12901 cacgagcaac aggattgatc gcttgaccat cgatatcgag gtatttttcg ggaataagtt
    12961 ctggaccgcc gtctatgggc tgccccattc catcaaagat gcgccctacc atatcttctg
    13021 atacggctaa ttccaaagga tgccctgtaa atcgaacctt ggttttggct aggttgatac
    13081 cagttgatcc ttcaaatagc tgtaccatag ccttgtcacc ttggacttct aagacttgac
    13141 ctttacgcct ttctccatta tgcaaagtaa tatctaccaa ttcgttatag tgcactcctg
    13201 caacttgatc aacaatcatc aaagggccaa ccacttcgct aaccgtccga tattctttga
    13261 gaacgctcat ctaaattcct ccctttgcta aaacgtggtg aatctctttg gtaaccttct
    13321 gagtaagccc tttaatctgc tctaagtttt cttctgggat aaatttgctg cgtgcgatgc
    13381 gatcgcgtac ctgagcagtg ccttccataa tctcattaaa ataagctccc aaagaaaggg
    13441 ctttgccggc ttcctcatta aaggtcaaaa tattggttag catggcctct tgtttcggaa
    13501 aggaagtaaa ggtatccacc gaatcaaagg cattttgctg gagataatcc tcccgaattt
    13561 gccgggcaac agccatggtc aaacgatctt gttcagacag tgaatcaagc cccaccaagc
    13621 gtacaatttc ttctagactg gcttcacgct gcaaaatagc catggcacga gttaccttgt
    13681 tggaccaatt agattgctgt ttacggtcaa tatagcttcc tacatcatct tgatacaatg
    13741 aataagacgt cagccagtta atcgctggga agtgacgccg ttgcgcaaga ggcgcgtcga
    13801 gcccccagaa aactttgaca atccgaaggg tgttttgagt gacaggctct gaaatatccc
    13861 ctccaggagg agaaaccgcg ccgatggctg taatggttcc ctcacgttct tgacttccca
    13921 aggtccgaac acgaccagcc cgttcataat attcggcaat acgactccct aagtaagccg
    13981 ggtagccttc atcaccaggc atttcttgta ggcgtcctga catctcgcgc agagcttctg
    14041 cccaacgtga tgtcgagtct gccatgatag ccacagaata gcccatatca cggaaatatt
    14101 cggcaatggt aatacctgtg taaatcgacg cttcacgcgc tgctactggc atattagagg
    14161 tgtttgcaat taacaccgtg cgctccataa tggactggcc tgtatttggg tcaattaact
    14221 ctggaaactc attcaaaacg tcggtcatct cgttgccgcg ttccccacaa ccgacataaa
    14281 taacaatatc aacgttggca aatttagcta tttgatgctg cacaactgtt tttcctgccc
    14341 caaatggtcc aggaacggca gcggcaccac cttttgtaac agggaaaaag gtgtcaataa
    14401 cccgttgacc tgtaaccaaa ggttcgactg ggataagctt ttgagcaaca gggcgacttt
    14461 gacgaactgg ccaagtctgc atgaggctac cttggtaaat ggaaccgtct tcctgcttaa
    14521 tttcataaac tgtatctgtt actgtgaagt cccctgcatg aatagccacc aaggtccctg
    14581 aaactttata aggaaccatg atacggtgct caatgacagc tgtttcttgc acagttccta
    14641 aaatatcacc tgcaactact tcttgaccaa cacttagctt gggaataaat gcccacttag
    14701 cctttcgatc aagacttggg atagccacac cacggattaa aaagtcgctg tccgttgctt
    14761 tttgaaaacg atcaagcggt cgctgaatac cgtcaaacat ttctgaaatc aggcccgggc
    14821 ctaactcgac cgacaaagga caaccagtag tcactactgg ttctcctgga ccgatccctg
    14881 atgtttcctc ataaacctga atagacgctt gatcgcggcg catttcaata atttctccga
    14941 ctaagccaag atgtcccaca cgacaaatat cttgaatatt agcttcttgc atcccagaag
    15001 ccacaacaag aggtcccgaa acggttatta tttttccttg gttcaccttt ttcctccttt
    15061 attttttcca aatcatacta actaatctat actgtcaagg tttaatgtga ctattttgaa
    15121 tagtcagcaa actatcctat gcgttcagct gctaacttca ccaattttcc tgtccttgca
    15181 tttcatcagt tagctactaa taagcctcaa acagagtata agtcctcttt gcctaacgtc
    15241 ttagtgttat aaaatatttt gaccgacagc cttttcaacc atggcttgta tgcgtgacag
    15301 gcctatccct tgcgctcctt gatgagttgg taatggtatg actgctggta gaacttgatt
    15361 gtcatagtga gcgagggctt ctggaatagc tgcagcaata tcttctgtga tataaataat
    15421 accaaagtct tccattgcta gttgacgcaa ctggttaata gcgtcttgtg gttttattac
    15481 tggaaaagtt tgaaacccaa tcatctgaaa aggtagaata acatctctgt taccaattac
    15541 cccgacttta tacaatgttt tggtcatgct attggtctca tcctttctat gacacgttct
    15601 ttgggtaaat cattagctaa agcagccgct aaaagccgta gattttttac ttcaaacgat
    15661 ttagctagca aaaaacgagc aagcacataa ggtccatcga cttgatattt ggccttcgca
    15721 aataaatggt aaaggcattc atcaacaagg tattctaact cagtcgtttg aagagtgcct
    15781 tggcgaagtt tctctgaata aggttttagg gctgtcatat agctatcagg tgttacattt
    15841 tcaaaccacg tcatcagatc cttatcatct tcaagtgtaa taaatgtttt acttggtcta
    15901 cttgcttcat cagataataa ctgcatcatg aaacttattg gtttattttg cgatttggcc
    15961 cgtctgacgg taatcagatt atacaaatca atcacaataa gaacagcttg ttggaaaaca
    16021 gggtcctcta atctttgtgc tatttgtttc aacgccttaa aataagctaa gtcagtacca
    16081 atttctaaga cgcgtatgtc ttgataatct tgatattcgg cccaaatgga ctggatttct
    16141 gttaccacct cttttggaaa ctcatcagaa gtcatcgtcc taatcaaatg ttccaaagcc
    16201 accaaaggct tgtcaccaat tggtagtaat aagtgactca gatctgcttg actagcttta
    16261 gcttttaaca acactttgac attatgatag gtgtaacgca aggtaaataa ttgtactatg
    16321 tcaggttgag gggtttctgc aaaagcccag cgataggtct tggttagctc agccattaag
    16381 atagattcta gccgatccaa atcgttgaga tcgtcaacag ttaggtgata gactgactgg
    16441 tgcaacagtc gagctaaggt tgttgtattg ggagcctgca atagcttatc aaattgctct
    16501 ttagtcaata actctttttc tttgacactg atagtagtgt ttaattctag aaatgttggc
    16561 atcgctagtc aaacctccta tatctctgaa aaaagcatat caatgatgcg ggagctttct
    16621 tctttaagaa ctgattctaa aaggtaacgg tataaataat tgtcatcgac ttggtctaaa
    16681 ctgactaaaa atcctgcttc ctgaggaatt agctcttgat tatagcttaa ttgaggaaat
    16741 gctaatctca gctcagcaca atcataagaa ctaaactttt gccctgtttt ttcgccaaaa
    16801 gtaacttgca atggctgttc tggatattta gacaagactt gcttcaaaaa agccaattct
    16861 tcttccttag aaaagttcgt catcttctcc aaagaagctt caaatagctc ctttatactg
    16921 tcttgtttta atgctagtag agcttgtctt tcttgatttt tgagttgctg ctgcgcaacc
    16981 tgaaattgct gttcaagagc ttttaactct ttttgacgct ttgcttttaa atcgtgtagt
    17041 ccttgctgtt gacgctcttt aaagtcagta tcaagactat ctgtcgctat ctttaggcac
    17101 tgttgacctt cttgatgtgc tttttcaaga acattttgtc ttaactgtgt tatatcattc
    17161 acctaatttc ccccttttga tagtgttagt ggtgccaccg ttttttaaaa tctagataag
    17221 gaccgttacc ttatccaatt ttatttaaga gaataaagga gacgacaaag gcaagaatag
    17281 cataggtttc aaccatagct gctaaaatga cacccttcat aaaatcttta gggcgcttag
    17341 ccaagatttg cataccagct acagaaacat tgccttggtg cttggccgaa aaataaccaa
    17401 caatagcaat tggaagagat accaaaaagt aagctaatcc ttggttaact gaaagttctg
    17461 gtgtcagttt catccaaatt aaaataccaa tagcaaagcc gtagattcct tgactaccgg
    17521 gtaacagttg caagataagc gcagacgtaa atttttcggg ttcttctttt aagagcgcag
    17581 ctgccgcttg accaccttta ccgacaccat aagctgagcc catgccacta agagctacgg
    17641 ctaaaacaat tcctaaggct gcgaagaaaa cgccaccatg tgctgtaaaa taatgtgcta
    17701 aatgttccat gttaattgtc ctccaaatct gtttcttcat tgacattgac ataattatca
    17761 gctaacttta aaggattgaa agcttttcct ccaccttcat aaaattttcc aaaaaactct
    17821 acgaaaataa gacgagcacc atgcacatat cctgaaagca ttgataagaa aatattgatc
    17881 gcatgcaaaa gaataaaaat aaagatacct actgtaaagc gcgtgactgg tggaaaaatc
    17941 ccaacaatca tgttaaaagc cgctccaata ctagctccag aaagccctaa tgccattaga
    18001 cgagtaaagc taaccaaatc acttaagtaa gagctaatgc catataaatt atataagcca
    18061 ctacctagac ctaaaaggct tttgcttttt agtaaagaaa caaccaaaat cccaaaggca
    18121 ttgcccaatg caagccactt accaataacc gataagtaag caaggccaga tacattctta
    18181 ccaagaataa ataacagcag acctaataaa ataaaagtcc aagctagact tgacgtatag
    18241 gccgtagcat atgctttcat ccttacttgt tgccatgctc ctaacaaaag cccaaatata
    18301 agtgtaacaa acccaaatag caaagaaaca accaaaatag taatcacatc cgttttagtt
    18361 gataataatg ccacaggtaa gtcaaaacca aagaaagaac cgtaaataag cccccatatg
    18421 gctactgaaa tagctaaaat attaaagaag gtcactaacc gtttactggt tttttggaga
    18481 ttaaaaaaga ccaatgcagc tagtgtcaca gcatatagca acaaaccata gcccaaatca
    18541 gctaccatca tgccaaaaaa agtaaggtat aaaggagcta aaaaaggtgt cggatctttt
    18601 tcttgatatt ttggcaaagc gtacatttct gtaaccaatt caaacggtgc aatgtagcgg
    18661 tgattacgta acttaatggg aacatcttcc caatcgtctg gcgtgacatc gtaactatcc
    18721 agataaaaca tatcacctag tgtcttagtc attagccctt ttaattggtt aaccgaatca
    18781 gcttctatcc acccttctaa ggctatcaga tgtcttgtac cgagtaattg ctttttagtt
    18841 tgctgccgtt gatactgact aaggacatag tctatttcaa cctgtaactg tgccagtatc
    18901 ttttgagact gcctaagctc ttttagtaga ctatcttttt cagctagcca attcgttagt
    18961 aactctttgt ttatacgaag ttgttctgat ggcagtagct gttctttata taataagggt
    19021 ttaaactgat atttctgtaa atgaatcgta tcttgtgctt gccaaaataa gacaaggccg
    19081 tactcaaatt ctgtatggta tacttcctca ataaaaagac ctttgtgctg ctttagctga
    19141 tgataaaaat gatcatttgc tgtactagga atcgttccaa ctcttgccga caaaaaataa
    19201 aattgcgcta agtcctgagg caaaacagtc aaggaacgcc acttttctaa ctcctgacag
    19261 tattctgtta gctggtctat tttgttttgc agctgctcta gtcgttctat cttttgtgac
    19321 atcattttca aagccgtttg agctgcttgt tgtcgatggc tttcttcgaa ctgtttaaac
    19381 gaaagagatg gcgttttttg tctcaaggct gttaactttc ctattggtgg taaaaacgct
    19441 gataaactag caaggccgtt ttctaactct tgttggcttt gtaagaggta ttgtaaagct
    19501 tcatcatcta gtagaggttt ttgatgcgtc agatcgtatt ggacgatttg tggcaacttg
    19561 acgttgcctt tgttaaaagc atcttgccaa tgttttagtt gcttcatgtc acgaacttca
    19621 actaattgag attgttgaag tgtttttaaa acaagatcaa gataatcttt ttcaaaaacc
    19681 attgccagct ttttcatttg actaatggcc atatgtctcc accaccttat ccactaactc
    19741 cctaacaacg gttagcttat gctcttctaa aatggcatga agggctagct gttgcgtcgc
    19801 taacctcttt tttgaagctt tttgttcttg acgattagct tcaaaaaaca cctcacgttt
    19861 agcttctaat agtagctgag tttcttgttc gtactcaagg aacagctgct ttaactcttc
    19921 ttcttttttg tcagctagag cttttttctt agcatcgtaa ctgtcataaa ttgttctagc
    19981 ctcttgttcg atactattca ttagtgacaa tagggtattc atcacatatc aactccttat
    20041 ctttatctat tgctaattct ttgactcact aggtacttaa aaacaaagct acaagaaagg
    20101 ctacttttgg gggttaatca accagcgact ataagctaga gctaaatctc taacctatct
    20161 actaacagct tttttgagat aggataattg cttgattaaa cgaacagcat ctttaagtta
    20221 agcgctttca attctgtcca taaaaacaat ggcttagttc agaaaaaggt tagctaaaaa
    20281 cctgtcaaag tagtaagatg acacagaact ctaaagcttt gtattgctgt ctttcgtgtg
    20341 ttatcttata cttctttagg catttagtaa ccttaatcta gttgacggta aggaaccttt
    20401 accagccaat agccaagcca atgtgataac agtataactg ccatcttgtt aaaagtcctg
    20461 tcaaaaagat gtttattagt ttctcgcttg taattcttgt tttgttacta aacggtaatt
    20521 tttaaagaca gaacctccaa tataacccac aattaagctg ataataatac atccaagggc
    20581 tgttatcaac actttagcga caggattata ggcaaacatc accgcaaaac cggcaatcgg
    20641 agtagctgtc cctggcgtat cattaaccaa tttcattagg gcgatcaaaa caccacatgc
    20701 agcaccacca acaaaattag tcacataaat cggaatggga ttggctgacg tcacatctgc
    20761 ctgagtcaac ggttcaatag caaaagcaat attgtctttt ctttcaccca attttaatcg
    20821 gtaaaaaaga acaccattca taaaagaaga gccaaagaca gataaggcac ctatagccat
    20881 cggaatacct gtcagaccaa gcatggctgt caaagccatt gatgacagcg gagctgttgc
    20941 tacaacaaca atcgtaccgc ctaatatcat tcccatgata atagggttgc tattagcact
    21001 tgaggtcagg atgtctccaa tagtcaataa agtactattg atcactggcg taattaactg
    21061 cgccaagaaa cgagttaatg gtgcaccgac aataataatc gagattaaat caagcccacc
    21121 aggaatattt ttttccatcc acttgattaa aaaagatacc acatatccag ccacaaaacc
    21181 tgggataata cctgttcctg aaactgacaa accaatcaaa acggcataac ctggagacac
    21241 accaattgca atggcaacca agatagcagc agctacccct gataatgagc catttgctcc
    21301 gcctacttca cttagaaact gaaagcctaa aaccttacca aaaaaagaat cttgaaaggc
    21361 ttcaactaaa aaagaggcac aagctgccga agccaaagct cccattgcct tggcaccatg
    21421 aggagcctta tagttaaaca agctaaaaat agctaaaaca agaatcaaaa gacttgttcc
    21481 aataataata tccataatct attccaccaa tctatctcat tacataagac actataactg
    21541 cttcactctg gcaacagctt cgacttcaat caaagcttgc aaaggaagcg ccgacacttg
    21601 aaccgctgtc cgaacagggt aaggctcttc aaacaaatca gtcatgacat gatttaatat
    21661 ttccacattg gtcacatctg ttaaataaac atttagctta tagatatgat tcaagtccaa
    21721 cttttgctct gccaaaatag attgtaaatt aacaaaaacc tggcgacact gtgcctcaaa
    21781 accatctgac aattgacctg tcactggatt aaggggtaat tggcctgcgg tgtatagaaa
    21841 atgtccttca atcgtataag ttgaataagg gcccattggt tctgggtagc tcttcatata
    21901 cgaacctcct cattgataat atagttaaat tttacaggaa accgcattca cagtcaataa
    21961 taaattctct ttttgataaa aaattattat taaggtgatt ggcaattgtt ttttagtcta
    22021 aaatgtatta ctatatttgt aaataagaag atagatatag gaagtttgac atggataaag
    22081 aaacgctaaa ctactggaaa acggttatca catttcttca cgatgtctta ggtgataact
    22141 atgagattat tttacatgtg attgataaaa atgatatcta tattggagaa ctcgttaata
    22201 gtcatatcag tggacggtct aaacagtctc ctctcaccac ctttgctctt gatttgatta
    22261 ccaataaagt ctataaggaa aaagattttg tgaccaatta caaagcaatc gttagtcctc
    22321 agcacaaaga agttcgggga tctacttttt ttattaaaga taaaaagggt aatctcgagg
    22381 gaatgctatg tattaactta gatatttcag cctatcaagg agtagctagg gacctcttaa
    22441 aacttgtcaa tctcaattta gaacatttca tcccaactgc taaagaacct aaaacagtca
    22501 caccccagcc agaagaagct gttgaaattt taacctctaa catccaagat attatcggtc
    22561 aaattattga tccctcgtta ctgagacaca atgtacatct tagccaagat gtcaaaatag
    22621 acattgttgc caagctttat gaaaaaggag tctttcaact aaaaggagcc gtctcaaaag
    22681 tcgctgatat tctatgtatt tccgaaccaa gtgtttaccg ctaccttaaa aaaattgaag
    22741 ccgatcaata actaaatcac cataaaacgc cagttaaaag tatttcagat aagcatcaca
    22801 atctctgata taccgatgac tgacgttttt tttactcaat atgcctttat ggcaagaaaa
    22861 ggctactagt cattaacctt cagctatgct tagaggtaca cctgtcgcag cttgaacctc
    22921 atcaaaagta aacccttcac tgatttcaat tacttggata ccatctggcg ttactttaaa
    22981 cacacccatt tctgtgataa taaggtcaac cacacctttt gctgttaaag gtaaggtaca
    23041 ttcttttagg agcttatgct ttcctttatt ggtatgctcc atagctacga tgactttttt
    23101 agcaccaact aataaatcca tcgctcctcc cataccagga accattttgc ctggaatcag
    23161 gtaattggcg atatctccat tttctgcaat ttctaaagca cccaagacgg tcaagtcaac
    23221 atgaccacca cgtataatgc caaaagaatc tgcactatta aagaaagcgg ctcctggata
    23281 aaccgtcaca ggctgtcctc ctgcattaac gatagtcgaa ttcggatcat ctgacttagg
    23341 acctagtcca ataaacccat tttcagattg aaaatacact gtcatttctt caggcacaaa
    23401 atttgctact ttggttggta gaccaatacc taaatttacc aaagtaccat cttctaattc
    23461 tttggccaca cgctttgcaa tacgattttg aatctcttct ttacttaatg caaccgccat
    23521 aactatactc cttctttaac aatgtaatct acaaaaatgt gtggtgtatg aacgcattct
    23581 ggttgtatgg tgccgactgg tactatttct cgcgcctgaa caattgttgt ttttgcacaa
    23641 gctgccatca attgattaaa attattttca gaaccactat actgtaaatt tcccatttca
    23701 tcagctttat tggcaaatat caaggcgaca tctgcctcaa atgggtattc taagagatag
    23761 gtttttccct tgatggtttt tgtttccttg ccttctgcca ctaaggttcc tacccctgtt
    23821 ggcgtgtaaa agccaccaat gccataagct ccgatgcgaa ttttttcggc gaaggttcct
    23881 tgaggaatga gctcaatcgt cgtttcaccg gcagtcattt ggcgcccagc ttctttattt
    23941 aatccaatat gtgttgcata aatggttttg aattgatgat tagccaccat ttttccaaca
    24001 ccgcgatcaa caaaaccagc atcattacag atcaaggtta agtcttttgt acctttgtca
    24061 accagtgcat caattaacgc ttctggtgtt ccattagcca taaaaccacc gaccataatc
    24121 gtgtcaccat ctttaatatg actgatagct tctgctattg ctattctttt attctctttc
    24181 atacggttac cttctatctt gttacgatga tactttgacc ttggccacca ccaatacaaa
    24241 gcgttgctaa gccatgtctc acatcacgct tagccatttc tgctaataag gtgactaaaa
    24301 tacgagcacc tgatgctcca atcgggtgac ccaaagcaat agctcctcca ttgacattaa
    24361 ctttttcatt gtcaaaacca aggtctcgtg aaaccgctaa agcctgagca gcaaaagctt
    24421 cgtttgcttc aatcaaatca atgtcatcaa ttgtcagctg agcctttgca agagcctttt
    24481 tcgtagcagg tattggtccg cagcccataa tacttgggtc tacacctgca cttgcataac
    24541 tagtgatttt agctaaaata gggagcccta attcttcagc tttttcttta ctcatcaata
    24601 aaattgccgc tgctccatca ttgattcctg aagcattacc agcagttact gtcccctcat
    24661 ctttgataaa agcagggcgt aactttgcta acttatccac tgtcgttcca aatttagggt
    24721 attcatcttg atcaacgagt aaaggttcac ctttacgctg aggaatagtg acaggtgcaa
    24781 tctcttcttt gaaacgacct ttttctatgg caagttgggc tttacgttgg ctatcagctg
    24841 caaaggcatc ttgttcttct ctggtcagtc catactgttg cacaatattt tcggctgtta
    24901 tacccatgtg ataacctgca aaagcatcac tcaacccatc tttaagcatg gtatctacta
    24961 ctttactatc tcccatacga gatccccaac gttggccttg taaaacgtaa ggtgcttgac
    25021 tcatgttttc ggtaccaccg actaaaacaa tatcagcgtt gcccgtttga atcttttgag
    25081 cacctaactc aactgctttt aagccagaac cacagaccat atcaatcgta aaagcagggg
    25141 tatcataaga aagccccgca tttagcgcta cttgccgagc aacattttga cccagacctg
    25201 catgtaacac attcccaaag atcacttcat caatggcatc acttttaaga ccggtatcag
    25261 ctaaaatttt tgtaacaact gtcaccccca aatctacggc tgataaagat ttaaagactc
    25321 ctccaaaatt tcctatcggg gtacgataag cagatgtgat caccacttct ttagtcatag
    25381 aaacttctcc tttctcatta ttgaaacgct tacattttta ttatataatg tgaactataa
    25441 taaacaaata tcgttttttt atatatgcta taactaaacg ttatcgaaag aggaaaatat
    25501 gaatatctca agcttggctt attttattga gattgttaat tgtgacttta acttaaccaa
    25561 agcagcccaa aaaagtcata tttcgcaacc cgcccttagt agttatatca agactatcga
    25621 aaaagaagaa ggagtcgttt tattccagcg tcaaaaaggg cgtctagtta gactaacctc
    25681 agttggcgaa cgcttttttg aaaatgctaa ggtggttatc gcatcacatg agcaattaat
    25741 ggctgatttg cggagtgaat cccaaaaata caaaggagaa atttcaatcg gtattcctca
    25801 actcatctct ggcattgttt tttctgagct cattccaaaa ctcatcgaag aaaatcccga
    25861 agttaaattt catattgtag aaacgggtgc ttatgaactg caaaaaaaac tgtttctaaa
    25921 agaagtcgat tttgcgattt tattaacacc cactacacta gatgctacta ttgctgatat
    25981 cgacattctc ctaagagatc aactctgcct ttatatgagt cacaaaacct ttcaagagac
    26041 gtttgatagt aatcctaaca tctctatcaa agcattacat cgtcaaaact tagtaacttt
    26101 tgataaaacc tttatgatta atcatcagct tactacctta tttgaagaag caaatagtct
    26161 tcctgtagtc aaatgttatt ctgcctcgtg ggatttttta ttaaattgca cgcgctattc
    26221 ctcttaccta acaatcctac caaggcctat tactcatttt gctcatatgg acggtttagt
    26281 ggaggtccaa ctgaccgaac atccaaaatg ggaagttgtt ctagcctctc tcaagcacaa
    26341 taaaataagc catttaaaac attatatcaa gcacaccatc ttagattatt tcacgaacca
    26401 gcgcttctaa ttgcttgact cagaccttaa aaaaacgcct gaaggaaaca atcccaggcg
    26461 tttcatgtag ttatttccta aaatacaaat aggtaaatga tggcaatacc tgtgaccacc
    26521 aagacacaag gaatagtata agccacaatt tgattgaatt ttagtttgaa gtttgagaga
    26581 taagataagg cccaaaaagg aactatcaag tttgttgtgg catctcctaa ttgataagcc
    26641 tgcaaaatct tacctaggtc attaccaact tcgatggttg cagggacgat atagggagct
    26701 tcaatcacaa attttgagcc tcctgatggt accgcaatat tcagcaaagc cgagtaaaga
    26761 taagcaaaga ccggccatgt tgtcccattt gaaatagcga caaagaaatg ggaaatctct
    26821 agtcctagac ctgtactttg aatgattcca aaaataccag cgtaaaatgg aaactgaagc
    26881 cccaagatga catgacccca tctttgaata gggaaccata atattctggt ccttgttgac
    26941 cacaaagaag caaccctaag cctaaaaata aaaagttaaa actattgaga tctagaccag
    27001 acaagcccac caccgaaaaa tgataaaggc tatagctaac aatggcccca ccaacaagat
    27061 acatcactaa gcgagatgcg ttcatcttct cagcaggtgt gtttcttgca ataacaacat
    27121 gtgaagcggt atcaagacta tgatgataga tctcatcatc aagttccatg attttagttt
    27181 catcttttgg gtgcgccaat aaagcaaagc aaagcggtac cagcatacac accactaaaa
    27241 gactgataaa tggaagattc aaaactgatt ctgtcagagg aacactttca ggaacaacct
    27301 gtttataagc atctgcgaca ctatttcgca aataatctgg agtagccgaa taaagcaccg
    27361 cagcaccaga taaaccagaa gtagctggta aaaaggtaaa aaataaagta gcaacaaaca
    27421 aaggtgtatg caccttaatc cctttttgcc tagcctgaac aagcaactct ttcccaaaca
    27481 caatggcaac catcatacca agaccccagt gtaaaaagcc aaagatagag cctactacaa
    27541 tagaaaaaat aaaaatctga gtcctggttt gaggcagttt ggcaagggac ttaaacattt
    27601 tatgagcagg tggagaactc gctacagcat tccctgtcgc aagtaaaata gtcatctgca
    27661 tggcaaagga caacagcccc caaaaaccat ttacccagcc atagataatc ccgcccgtct
    27721 tttccgtacc aataaaggga ctatccgtca tcaacacaga catagtaacg actaaaaagg
    27781 ttaaaataaa acagataaaa agcgattctg gcatccattt cataaagcca tcaatatagc
    27841 gatccataaa cctttttttg gttttgatgt tattcatgtt gtcaattcct ttcacgttgt
    27901 ccacaagcac ttttgttctt ttgatcagta acctatcgat aatattaata agcg
//
LOCUS       DAUNLR010000022        27233 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUNLR010000022 DAUNLR010000000
VERSION     DAUNLR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27233
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.022"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..281
                     /locus_tag="VLL59_000933"
     CDS             <1..281
                     /locus_tag="VLL59_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509063.1"
                     /translation="LTQQDLAEEIYVHYRTIQRWENEHKIALDQAQLLADHFDVSVAY
                     LLGYSDTTKDNKDFITISVKEYNELKNRSDALDGIIETLKDKKCESYF"
     gene            295..1197
                     /locus_tag="VLL59_000934"
     CDS             295..1197
                     /locus_tag="VLL59_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HER6509064.1"
                     /translation="MADNKKYYYLKLKENFFESDEAIILESMPDGYIYSNILLKLYLR
                     SLKNDGLLMFNNLIPYNAQMLATITRHQIGTVEKAIQIFRDLQLIEILDNGAIYMTNI
                     QNFVGKSSSQADYMRNYREKKGGLTNVNQNSYICEREIDIEKEKEKERELDKEKEYIA
                     EQSLTEYLFPDWLEEKYVEQVKKGNPKNFDYRIPIAYLNQKTNSNYKFVDSNVNLVKA
                     RLRDGYNLDDFKAVVDKKCGEWGNSDMAKYLRPSTLFNASKFESYLNQPEVAKSDYYQ
                     KQQGQRFSQAELDELKKPDPKYGF"
     gene            1207..2049
                     /locus_tag="VLL59_000935"
     CDS             1207..2049
                     /locus_tag="VLL59_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HER6509065.1"
                     /translation="MAFGLMTRESMLASGVIRDTGKTCEKHEMPIYARKMPNHGNRET
                     EFCWQCTTEYIQTKSNAVDIAYNNQSLLAKGYNVFYKESVLSKEIASATLKNYKEHSA
                     VDTQALNYAKRITRDYVKGMEGNSLLQGPPGVGKSHLSMSIAKNINEMFKSYNQSKSV
                     IFVSVPLLSALVKDTFDYDDKKNSKYSQERMSKLLINCDYLILDDLGKESTTGNTIKS
                     ASGWAYTFLFNILDNRTNTIINTNFSRAELMKIYDAAFVDRIIKGAKNNIFKYPDNAE
                     SKRF"
     gene            2049..2186
                     /locus_tag="VLL59_000936"
     CDS             2049..2186
                     /locus_tag="VLL59_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509066.1"
                     /translation="MELTLTTFFGLSEEHAAKIMALDEDVRTKKIEELRAWRECSKVT
                     F"
     gene            2199..2546
                     /locus_tag="VLL59_000937"
     CDS             2199..2546
                     /locus_tag="VLL59_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509067.1"
                     /translation="MIMPLDELEKRIFCYLPIGSNMMVNSKEICRTFDIKDPKTLRDI
                     IHGMVMKGYLIGSSRRKGGGYYLIDDDDERTEAISSLESQVRKEQKRINILKNGNLNE
                     FAKVASEVRNGRN"
     gene            2533..2787
                     /locus_tag="VLL59_000938"
     CDS             2533..2787
                     /locus_tag="VLL59_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509068.1"
                     /translation="MVEIRINGETITFDSNFRDALIFTIDCLRGSDEPTLKRTYKEFK
                     DYTDEDLMDYIETEFDVEPELIPNRRIDSKWVFKQHILDN"
     gene            2809..3138
                     /locus_tag="VLL59_000939"
     CDS             2809..3138
                     /locus_tag="VLL59_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509069.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNKKDVLAYNVELTDSIQLASF
                     LPEEAYNIQKEKIDNLAETLGCDVVVIEASYDLKFIDGEDVPELTKEQKVKSMVNGMF
                     EQVFGGE"
     gene            3141..4070
                     /locus_tag="VLL59_000940"
     CDS             3141..4070
                     /locus_tag="VLL59_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HER6509070.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIEEDNQDST
                     ISTPKDITPQETNSLDDLIDHQSEKKDAPSNLKDASEYLHSEPEKTLTDENKTVLEDT
                     SYPADEVPDFDQETGEVLASEGNLFDNLGDLMP"
     gene            4067..4864
                     /locus_tag="VLL59_000941"
     CDS             4067..4864
                     /locus_tag="VLL59_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HER6509071.1"
                     /translation="MTKLDLLGKDYYSRESAIKYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFESKEAHEEFKAQNGSEMISTRGTTKGQLKKDYLVAEQMI
                     EALKNDSNFMAIYQGEKEAAITGFLGEVEFKGKIDCLNVERGYFVDIKTTKGPIDDTI
                     WNGEERVRWFEAYGYILQMAAYKNMLEAKYNKPFEPIIYAVTKETPPDTRAIRIQSID
                     AMQMELDSLAQSIKRLDDVKKDVEKPDPCGHCEYCRANQLTQRVMIF"
     gene            4874..5041
                     /locus_tag="VLL59_000942"
     CDS             4874..5041
                     /locus_tag="VLL59_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509072.1"
                     /translation="MTKYYVSAKIANLDIGAEIEAENQHMAPIAFKETYDHLLRFGSH
                     KLRILGVEEVN"
     gene            5214..5612
                     /locus_tag="VLL59_000943"
     CDS             5214..5612
                     /locus_tag="VLL59_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509073.1"
                     /translation="MYYEFVLSNTKQKKEMLSSNDRLHFRKSASITKGLRQLAKLKSN
                     GLTKKHTKNNPCKVIVTVFTPTKRRFDPPNIYPTIKAILDGFTDAGVWDDDNHEIIKS
                     LTFRYGGLSNVKEKYRIAIEILEMETHDYY"
     gene            5599..5796
                     /locus_tag="VLL59_000944"
     CDS             5599..5796
                     /locus_tag="VLL59_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509074.1"
                     /translation="MTTTKKHVVRVYNKGITATYMVYDKKLFKEHEFATKREAMQFIR
                     QLELSNDKRATEYYLREVERC"
     gene            5803..6075
                     /locus_tag="VLL59_000945"
     CDS             5803..6075
                     /locus_tag="VLL59_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HER6509075.1"
                     /translation="MRLKKIEELEAACQDTTDNIKKPSHYQGRHGMEAIDVVKNFSAC
                     PEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIKKLEEVE"
     gene            6072..6341
                     /locus_tag="VLL59_000946"
     CDS             6072..6341
                     /locus_tag="VLL59_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509076.1"
                     /translation="MKKPNRYPYSKSKFNGCIYQLCAASFKDEQYVKDLKSCGIHYQI
                     TKVGHFPDVFIKIDNLEQLQALIDKTGHDLILSKNEIWIYDDYME"
     gene            6351..6635
                     /locus_tag="VLL59_000947"
     CDS             6351..6635
                     /locus_tag="VLL59_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509077.1"
                     /translation="MTTDELLQNLRDDLNKIMNVLKNDWKALLFLAIAIFGMMVTVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRASEQNQRQTKWIAELTGNGG"
     gene            6637..7269
                     /locus_tag="VLL59_000948"
     CDS             6637..7269
                     /locus_tag="VLL59_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HER6509078.1"
                     /translation="MIKIDEIHRILGIDEVYKAPKRLMDILFDKDSREDIFRQFLDIE
                     TDLSYDWFMRYFEDEHADRKNKKQDFTPLSVSKLLTGLVSGHTYHESAVGTGGILIQA
                     WQRHRISSNPFTYKPSDYWYQVEELSDRALPFLLFNMSIRGINGVVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEQEFNVKEWIGDAIVHVESKLNAR"
     gene            7670..8110
                     /locus_tag="VLL59_000949"
     CDS             7670..8110
                     /locus_tag="VLL59_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017794969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HER6509079.1"
                     /translation="MARNEITEAHKILKELQMIPKIIKELKLDIERTQASLLSSPQWS
                     DMRVSGGVRQSQTDKNVTIIDAKDYNLAEIDKLLKRKEEILDIISKLDAEPRLLLIRA
                     YVIEKYPSDCIEKYYSEKKYYTVKRIAIDQLNAVIGQQMTVHGQ"
     gene            8192..8536
                     /locus_tag="VLL59_000950"
     CDS             8192..8536
                     /locus_tag="VLL59_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HER6509080.1"
                     /translation="MSQLRADKKGTHRAAFDRNKKKLLKTATICGICGKLVDKSLKYP
                     HPLSAAIDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRNLP
                     QSRDWSSFAFKK"
     gene            8685..9041
                     /locus_tag="VLL59_000951"
     CDS             8685..9041
                     /locus_tag="VLL59_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509081.1"
                     /translation="MKKKCLICKKNFQAKTNRTLYCSEECRKKGNREKQRKLMKQKRA
                     EQRKEKKKVLNPNTDVTEKPKKIRNLAQHYKKLKKEILANESEFGFTGITLIEGIDVH
                     EENFVDLVMQKIKEQK"
     gene            9038..10306
                     /locus_tag="VLL59_000952"
     CDS             9038..10306
                     /locus_tag="VLL59_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HER6509082.1"
                     /translation="MNYMGMGYLRRKLALFKTGVDKRYRYYAMDDRDDTRSIVMPNNV
                     REMYRSVLEWTAKGVDSLADRIIFREFANDDFNAWEIFKANNPDIFFDTAIQSALIAS
                     CCFVYIMPGAEDGLPKMQVIEASKATGILDPTTFLLTEGYAILESDSNGNPTLEAYFT
                     DKDIWYYPKKGKPYNIKNPTGHPLLVPIIHRPDAVRPFGRSRITKAGMYHQKAAKRTL
                     ERAEVTAEFYSFPQKYVLGMDPDAEPMEKWRATVSTLLEISKDEDGDKPTVGQFTTAS
                     MSPFMEHLKMYASLFAGGSGLTLDDLGFPSDNPSSVEAIKAAHENLRAAGRKAQRSFA
                     SGFLNVAYIAVCLRDEFPYLRNQFMDTEIKWEPLFEADANMLTLVGDGAIKLNQAIPG
                     FMDADVIRDLTGVKGSDNPTPKATEVTTDG"
     gene            10299..11792
                     /locus_tag="VLL59_000953"
     CDS             10299..11792
                     /locus_tag="VLL59_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509083.1"
                     /translation="MADDVLPKILKSVQQDFEKYFGKSEVVAKAFADLKSKKATYKTV
                     NEFGIEVGKLLSLALTGSITSDKLPDGKMYYNIAKRLLDETMGRNYKLISGYAGDVQR
                     ILNENAQIGLKVQRPPLNRDKINGMVNRLDSENTFDDVKWLFGEPIVNFSQSIVDDTI
                     KANADLQYKTGMTPQVVRTESGNCCEWCREVVGTYSYPKVPKDVWRRHQRCRCTLDYD
                     PKNGKVQSAWSKIWRKKEKTQESIERVEKFKESALVESIKNDIAKLDMTKVGPSDIID
                     IGKRINYHFRVSEHIGDKEKLKEIFSNFREIGGEIPKNTWAKGSSKLVKDQLQEAFQN
                     YPTEWAAVPDGIGKKLKAIKRKRGYFDGYDEDLVIATNGTRKTTPYHEIGHMIELVNP
                     DLVRLEKAWVDKRTANEAEVRLKDIFPSSNYGIGEVTKKDDFISPYIGKYYSDAAEVF
                     TMGLQGIFVPEERFAKSFDKKTWKYDYKTINDDPEFLNFIIGLFVKV"
     gene            11798..12022
                     /locus_tag="VLL59_000954"
     CDS             11798..12022
                     /locus_tag="VLL59_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509084.1"
                     /translation="MEPKLHRQLRQKYDDAEKQYLEKFGEDSLDRVFFWEPDVYFDEW
                     KKVLPDATLELNKAINSGVAIDPDPENAIY"
     gene            12072..12251
                     /locus_tag="VLL59_000955"
     CDS             12072..12251
                     /locus_tag="VLL59_000955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509085.1"
                     /translation="MNKISLNVEMTWENKDEFQQIMNKVNETKEAYEKALEAAENFVP
                     KMSCATKLNKGEGDE"
     gene            12244..12510
                     /locus_tag="VLL59_000956"
     CDS             12244..12510
                     /locus_tag="VLL59_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509086.1"
                     /translation="MNKRIKKKRKLERAIVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQSAIADIAIDVNYIKKNYKRKWGK"
     gene            12620..14035
                     /locus_tag="VLL59_000957"
     CDS             12620..14035
                     /locus_tag="VLL59_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HER6509087.1"
                     /translation="MVTKTKTKLGNQRPTQSVNLHFAKSLAHEAINYYKKTGLSCYPW
                     QVNMLIPIMAIDENGLWVHQKYGYAIPRRNGKTEVVYIVELWALHKGLKILHTAHRIS
                     TSHASFEKVKKYLEMSGYVDGEDFISNKAKGQERIEFKASGAVIQFRTRTSNGGLGEG
                     FDLLIIDEAQEYTSEQESALKYTVTDSDNPMTIMCGTPPTMVSTGTVFEAYRKDCLKG
                     NKRYSGWAEWSVPEMVKINDVSSWYISNPSMGFHLNERKIEAELGEDEIDHNIQRLGY
                     WPSFNQKSVISEKEWAKLKVEQVPELKSKLFVGIKFGQDGNNVSLSIAARTSENKVFV
                     ETIDCLSVRNGTQWIINFLKSADIAKVVIDGASGQELLAQEMKDQGLKKPELPKVAEI
                     ITANMMWEQGIMQETICHSDQPSLTAVVTNCEKRQIGSNGGFGYKSLYDDRDISLMDS
                     ALLAHWICYTTKPKRKQRTSC"
     gene            14116..14577
                     /locus_tag="VLL59_000958"
     CDS             14116..14577
                     /locus_tag="VLL59_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HER6509088.1"
                     /translation="MSEFKVIEKQEELDTIVKARIAREREKYQDYDQLKTRVEELETE
                     NSSLQTALNDAKSNTDSYTEEISTLKNQIADYETANLRTKVALQYGLPIDLADRLQGD
                     DEDGLKVDAERLASFIKPSQPQPPAKSNEPNIDSNADANYRALVQGLSTED"
     gene            14602..15513
                     /locus_tag="VLL59_000959"
     CDS             14602..15513
                     /locus_tag="VLL59_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HER6509089.1"
                     /translation="MGTETSKASLFDKHLVSDLINKVKGHSSLAKLSSQKPIPFNGSK
                     EFTFTLDSDIDVVAENGKKTHGGLSLEPVTIVPIKVEYGARLSDEFLYATEEEKIDIL
                     KAFNEGFAKKLARGIDLMAMHGINPRTKKASDVIGTNHFDSKVTQVVKFTESEDADAN
                     IEAAVNLIQGAEGVVTGLAMDTEFSTALAKVTNGEMGPKMYPELAWGADPDSINGLKS
                     SVNTTVGAGADEAESKDLVIIGDFESMFKWGYAKQIPMEIIKYGDPDNSGKDLKGYNQ
                     IYLRAEAYIGWGILDAKSFARVTKGEV"
     gene            15513..15713
                     /locus_tag="VLL59_000960"
     CDS             15513..15713
                     /locus_tag="VLL59_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509090.1"
                     /translation="MLYVNSKTGASFYSSVPVCGGDWTLVEQQTGEKAKTVAEIKRQL
                     DAAGIKYSSKAKKPELEALLPG"
     gene            15723..16145
                     /locus_tag="VLL59_000961"
     CDS             15723..16145
                     /locus_tag="VLL59_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage Gp19/Gp15/Gp42 family protein"
                     /protein_id="HER6509091.1"
                     /translation="MGNFATTDDVILLWRPLSVDELKRANALLKVVSDTLRMEADKVG
                     KDLDKTMVDKPYFVNVIKSVTVDIVARTLMTSTQGEPMTQESQSALGYTWSGSYLVPG
                     GGLFIKDSELKRLGLKKQRYGGIELYGEIERDNSCFSR"
     gene            16105..16443
                     /locus_tag="VLL59_000962"
     CDS             16105..16443
                     /locus_tag="VLL59_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509092.1"
                     /translation="MAKLKGITVALVDKSISEKDPFGNPVTVDFDIKIENVLVTPATT
                     EDITNQLSLTGKKVEYVLAIPKGDEHDWENKEVRFFGKKWRTVGVPLEGIEELIPLDW
                     NKKVMVERYE"
     gene            16436..16672
                     /locus_tag="VLL59_000963"
     CDS             16436..16672
                     /locus_tag="VLL59_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509093.1"
                     /translation="MSKFKFKLNRTGVAELMKSSEMQQVLTTKATAIRERCGDGYVQD
                     IHVGKNRANAMVSTKTIKAKKDNSKNNTLLKAVR"
     gene            16673..17008
                     /locus_tag="VLL59_000964"
     CDS             16673..17008
                     /locus_tag="VLL59_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509094.1"
                     /translation="MIEVIIKKYLDEHLDVPSFFEHQKDEPARFIILEKTSGAKQNHL
                     LSSTFAFQSYAESLYEAALLNDKVKQVIEQLDVLPQVSGVHLNADYNFTDTATKRYRY
                     QAVFDINHY"
     gene            17024..17614
                     /locus_tag="VLL59_000965"
     CDS             17024..17614
                     /locus_tag="VLL59_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6509095.1"
                     /translation="MANDTKNVTSAKPKAGGAIYSAPLGAKLPEDAKSELDTKFKNLG
                     YVSEDGVVNEDTRSSENIKAWGGDIVGSVQTEKEDKFTYKLIESLNVEVLKEVYGAAN
                     VTGDLSGGIQIKSNSKELEAHVIVVDMIMNGGILKRIVLPNAKVDEVGEIKYVDGEVV
                     GYETTLKCFPDKDGDTHREYIVKPGEANKKENSFEM"
     gene            17625..17888
                     /locus_tag="VLL59_000966"
     CDS             17625..17888
                     /locus_tag="VLL59_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509096.1"
                     /translation="MEILKGKTTSGFEYEIPKKRLKNFELVEAIAEEETDPTAVVKIV
                     NLLLGDAAKSLKEHVRDAEGIVDVEAIGVEIKEIFESQKDLKN"
     gene            17903..18274
                     /locus_tag="VLL59_000967"
     CDS             17903..18274
                     /locus_tag="VLL59_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5361 domain-containing protein"
                     /protein_id="HER6509097.1"
                     /translation="MIVKDDDALTCDLAETYGIYDYKKLPAYQVAVFAVGLRSNSRIK
                     MALSGETEALDTVLLAGIYDNTNLLFWSKTKDGQSGQNKPKSMVEALSGSKSQKANEV
                     ISFASGEDFANARKQLLGGDG"
     gene            18274..20631
                     /locus_tag="VLL59_000968"
     CDS             18274..20631
                     /locus_tag="VLL59_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509098.1"
                     /translation="MATELGQAYVQIMPSARGISGAISKQLDPEARSAGLSAGSLIGG
                     NLVKMIGGAIAAAGIGKMISSALSAGADLQQSFGGIDTLYKGAETAVKGFAKEAYKAG
                     ISANTYAEQAVSMGASLKQSLGGDAVAAAKAANMAIMDMADNSAKMGTDITSIQMAYQ
                     GFAKQNYTMLDNLRLGYGGTKEEMKRLLSDAEKLPAAMGKKFDLSNYADVVEAIHLVQ
                     DNMGIAGVAAEEAKTTFSGSLAAMKSSFTNVMAGLSLGDDIRPALRGLAETTSNFLFG
                     NFIPMVANIFKGLPSAIGTFIGAAAPIITSQFQGLMSSLGISIDLSPITAKFAQIGQN
                     LQPVFNGLKTAFGQLPSFFTSIGNAVAPVIDTIISGLARLDFSGFQSLISAILPALQA
                     GFQTFMAIVGPAISQLVNSFVNLWNACQPLVTILSGALMPAFQILGAFLGGVLQGILG
                     SISFAFDALKVVVEFLTPIIDWLVQGFNAIAPALQIGAQWIGYIIGMFTSLGASGQGL
                     SSILSSAWGNIKTVVSTAKNMITLAIDGIKLVFSNLGNAGNILKGLLSAAWSAMQNAV
                     VIAKGVINGAISAIKTAFSSFGNLVSSVSGTIKAVIGSLKNVFYSLASIDLVGAGRAI
                     MQGFLNGLKSMWGAITGFVGGIADWIRKHKGPISYDKVLLKPAGKVIMQGFNTSLMDG
                     FKEVKSNVSGMADDLAGTMTGKSLSLGIDAKPSVTADDLLSSNTSSKSTIGSTTSDLS
                     LFFVKVLALLQDILDKNTDVYLDKEKVSAILYEEFAKIMARERIV"
     gene            20628..21323
                     /locus_tag="VLL59_000969"
     CDS             20628..21323
                     /locus_tag="VLL59_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509099.1"
                     /translation="MIPKVIIDDFDTSTIPNCVLTGYDVGDILSPSFVENEVYGMNGT
                     NRELESYNESKPTLSWHLNSFDDAVNLVNRLDGLSKKIEFWHIPNSFYYYDCLSVKIN
                     AVNMKSWRVTLKLALYPFRYAKGISDVTITGNGNINNTGNVFSEPKIVVEGTGKGTLT
                     IGKQVMELNLSGKATIECKHGQQCVYDTGGNVKNSIRIRGSFFEIQPGTQGIAVSGGI
                     TRLTISPRWRYKV"
     gene            21305..23281
                     /locus_tag="VLL59_000970"
     CDS             21305..23281
                     /locus_tag="VLL59_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6509100.1"
                     /translation="MEVQSLISIKDDNTPLVAAFEDEISQEANSDYKLSFKYPAKHDY
                     RPLIKKGIILEADDLHGTQLFRVFEITKRHGYINVYANQIADDLNGYAINSISVDRVQ
                     GMKVMSELAGSIKRDHPFSFFSDIDGRHTFNQSDVSVMDALANGKHSVMGQWGGELVR
                     DKYQVNLLKKAGKDTEALFMYKKNLKSYEETDTIKGLISILHLVAEVEEEHEGEAREA
                     SDGNIGHSESPKKKTIRATVESKLKDTHPIIVEKSIKVQDQDVKTEEDLLAYGKKYFE
                     STLCDIPGNSLKIDVTNNYEGNVRLFDTAIVFHELYDRDLRMQITGYKFAPMANRLKS
                     ISFGEIKTNLAKQISSQIDNKVAEATAQHDAAFEAKLQKQIENADRVFDTKEAKLRKE
                     IEDGIKKAEANAEVKVAEVNAKVLEAEKIAKEVDERLKKFLASADAKEQDFDKKLEEF
                     RTSLKDLEVDEKQIDDALAKAGFSKDSLADIKAKLEDTSETATVTANIVGSTGGTFYN
                     RNRLDGDTDKVITFEQGYIDIAHNGEGFEEGKTYTISFEATCELLRKVGITVTQANMK
                     GARLVLTPKNPKLVVESFGLTKDTETINVYPFSYTVLVTSDWYKSKQIDLNASEVQEL
                     ALEMAYKDVVDGNNATIAGQWSDSPQIILDGGKK"
     gene            23278..24393
                     /locus_tag="VLL59_000971"
     CDS             23278..24393
                     /locus_tag="VLL59_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HER6509101.1"
                     /translation="MSENIPLRVQFKRMKAAEWASSDVVLLEGEIGFETDTGFAKFGD
                     GQNTFSKLKYLTGPKGPKGDTGIQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQ
                     KEETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLRLKPNSGIKPSS
                     SVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFDKSALFVDYSGKTNAVN
                     IAMRQPSTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPSANAKYDENAAA
                     LSIDIVGKRGASGNGTAAQGIFINSSAGTTGKMLRIRNKNVDKFYVGPDGGFWSCANS
                     TVAGNLTVNDPTSSKHAVTKDYVDKEIAKLKELIQKK"
     gene            24408..26192
                     /locus_tag="VLL59_000972"
     CDS             24408..26192
                     /locus_tag="VLL59_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509102.1"
                     /translation="MSRDPTYTINEHDLSFKDGRFYVTFRADKSSETVRLNSSCLGNT
                     VIKRLQVEDDETMHDFVKPKVTTQQPFGLAKQVKEIDLELKDPKSDLWGRIKANNKAM
                     LVEYGNKEIASAIAQSAEKILTQVKSLDDERYSKFEQTLEGIKQTVKSESVESARTQL
                     ASMFDSRITRLDGKYSRLTQTLDSLSTRLDDGLGNYSTLSQKIGGVESRVSSLSGNVS
                     RFSQTAQGLQSQITDASQNYSRLSQTVQGIQTTVRDNQTGTASRIRQLSDLISTKVTK
                     GDVETTIAQSYDKIALAIKDKLPKSKMTGNEIVSAINLDRSGVKITGKNITLDGNSYI
                     SNAVIKNAHIANMDAGKINTGYLSANRIAAEAITGDKIKMDYAFFNKLTANEGYFRTL
                     FAKDIFATSVQSVTLSASKITGGVLAATNGASQWDLNNANMTFNRDATINFNSKNNAL
                     VRKDGTHTAFVHFSNATPKGYRGSALYASIGITSSGDGINSASSGRFAGLRSFRYATG
                     YNHTAAVDQTELYGDNVLIADDFSINRGFKFRPDKMEKVLDMNDLYAAVVALGRCWGH
                     LANVGWNTAHSNFTSAVNRELNNYITKI"
     gene            26204..26632
                     /locus_tag="VLL59_000973"
     CDS             26204..26632
                     /locus_tag="VLL59_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HER6509103.1"
                     /translation="MQLTIKNKDLNTLYRVLDKIKVTNMRANRGRAKLLAKVEGKLSE
                     YAKDEVDIIDQYVAKNDDGKWITDDKGNSKIEDTSKLAELNDFLDELASEPIVIKGGE
                     YSKRFIDFLEYLAESEDEFTAQEIIIVDSILEQYEGSKGE"
     gene            26635..>27233
                     /locus_tag="VLL59_000974"
     CDS             26635..>27233
                     /locus_tag="VLL59_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509104.1"
                     /translation="MKTLTLSGKPYPIHEGGKVVKTEVRLIGDNGLFIPIELIGDQTA
                     KGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQ
                     AKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGMLELIEPVKKGKYQAYDVFTVV
                     DDKHEDEAGEGNLVFVHVNEPFTYEAQTLEELEEEDKVTV"
BASE COUNT         9419 a         4515 c         6009 g         7290 t
ORIGIN      
        1 gcttgactca gcaagatctt gcagaagaaa tatacgtgca ttataggacg atccaacgtt
       61 gggaaaatga acacaaaatt gcgcttgatc aagcgcaatt actagcagat cattttgatg
      121 tatcagtcgc ttacctgctc ggatatagcg atactacaaa agataacaaa gattttatca
      181 caatatctgt caaagagtac aatgagctta aaaaccgatc agatgcttta gatggaatta
      241 ttgagacgtt aaaagataag aaatgtgaaa gctatttttg aagaagggag ataaatggca
      301 gataacaaaa agtattacta cttaaaatta aaggaaaatt tctttgaaag tgatgaagca
      361 atcattttag aaagtatgcc tgacggctat atctatagca atattttgct caagttatat
      421 ctaagaagtt taaaaaatga tggcttatta atgtttaaca atcttattcc ttacaacgca
      481 caaatgcttg ccacaattac aaggcatcag attggcactg tcgaaaaggc cattcaaatt
      541 tttagagacc tacaattaat tgaaattctt gataatggtg cgatatatat gacaaatatt
      601 caaaattttg tcggaaaatc aagctcgcaa gctgattata tgaggaatta cagagaaaaa
      661 aaagggggtc ttacaaatgt aaatcaaaat tcttacattt gtgaacgaga gatagatata
      721 gagaaagaga aagagaaaga gagagagtta gataaagaga aagaatatat tgccgagcag
      781 agcctgaccg agtatctatt tccagactgg ttagaagaga aatatgtcga acaagtcaaa
      841 aaaggtaatc cgaaaaactt tgattaccgt atcccaatag cttacctcaa ccaaaaaacg
      901 aactctaact acaagtttgt agatagcaac gttaatcttg ttaaagctag attgagagat
      961 ggctataatt tagatgattt taaagccgtt gtcgataaaa agtgtggcga gtgggggaac
     1021 tccgacatgg caaaatatct cagaccatca actttgttta atgctagcaa gtttgagagt
     1081 tatcttaatc agccagaagt tgctaaaagt gattattacc agaagcagca aggacaacga
     1141 ttttcgcaag ctgagttaga cgagcttaaa aaaccagatc cgaaatatgg gttttaggag
     1201 gtatctatgg cttttggttt aatgacgaga gaaagcatgc ttgctagtgg cgttattaga
     1261 gatactggaa aaacatgcga aaagcacgag atgccaattt atgctaggaa aatgccaaat
     1321 catggcaata gagaaacaga attttgttgg caatgtacaa cagagtatat ccaaacgaaa
     1381 agtaatgcgg ttgacattgc gtacaacaac cagtcgttgc tagctaaggg ttataacgtg
     1441 ttttataaag agagcgtttt atcaaaggaa attgctagtg ctacgttgaa aaactacaag
     1501 gaacatagtg ctgtagatac acaagcgcta aactatgcca aacgaatcac cagagattat
     1561 gttaaaggaa tggaaggtaa ctccctctta caaggacctc caggagttgg caagagccac
     1621 ttgtctatga gtattgctaa aaatattaac gagatgttta aatcttacaa tcaatcaaag
     1681 agtgtgatat ttgtttcagt acctttgttg tccgcattag tcaaagatac atttgattat
     1741 gacgataaaa aaaatagcaa atattcgcaa gaaagaatgt caaagcttct catcaattgt
     1801 gattatctga tacttgatga cttaggcaag gagtcaacca caggtaacac cattaaatct
     1861 gctagcggtt gggcatatac gtttttattt aatattttgg ataatcggac aaatactatc
     1921 attaatacaa attttagtag agctgagctt atgaaaattt acgatgctgc ttttgtcgat
     1981 cgcataatca aaggtgcaaa aaacaatatt tttaaatatc cagataatgc agaaagtaag
     2041 aggttctgat ggaattgaca ctaacaacat ttttcgggct atctgaggaa catgcggcaa
     2101 aaatcatggc gctagatgaa gatgttcgaa caaagaaaat tgaagaattg agagcatgga
     2161 gagagtgctc aaaagtcacg ttttaggaga gatttaatat gataatgcca ctagatgagt
     2221 tagaaaaaag aatattttgt tatttgccga taggaagtaa catgatggtt aattcaaagg
     2281 aaatttgccg aacatttgac atcaaagacc cgaaaaccct gagagacatt atccacggaa
     2341 tggtaatgaa aggctatttg ataggttcta gccgccgaaa aggcggaggg tactatctaa
     2401 ttgacgacga tgatgagcgt acagaagcta tcagctcact tgaaagtcaa gttagaaaag
     2461 aacaaaagcg gataaacatt ttaaaaaacg gaaacttaaa cgagtttgca aaagtcgcta
     2521 gcgaggtgcg aaatggtcga aattaggata aacggagaga caatcacatt cgatagcaat
     2581 tttagagatg cgcttatctt tacgattgac tgcttacgag gcagcgatga acctacgcta
     2641 aagcggacgt acaaagaatt taaagactat acggatgagg acttgatgga ctatatcgag
     2701 acggaatttg atgtggagcc tgaattaatc ccaaaccgca gaattgatag caaatgggtt
     2761 tttaaacaac atattttaga taactaaaac acaaaaagag gaaatgaaat gaacatcaaa
     2821 gaaaaaattg tagtgctaag aaacactgaa gacggaagtt ttttaaagag tttcaaaaac
     2881 aaaaaagatg tacttgctta taatgtggaa cttacagata gcattcaact ggcatcattt
     2941 ttaccagaag aagcttacaa catacaaaaa gaaaaaattg ataatttggc agaaacgctt
     3001 gggtgtgatg ttgtagttat cgaagcatca tatgacctaa aatttattga tggcgaggat
     3061 gttccagagt taacaaaaga gcaaaaagtt aaaagtatgg taaacggaat gtttgagcag
     3121 gtttttggag gtgaatagag atggcaaatc aattatcaac atacacacac aaacaatttt
     3181 ttaacgcccc aacaattcaa aaagcttttg atgacgtttg gaaaggcgcc gggacacagt
     3241 tcgcagtaag catcttgtca gtactacaag gtagtcaaag tttgaaatcg gcatctaatg
     3301 aatctattta tgcagcagct atgaaagcag ccgtgttaaa tctgcctatt gagccaagct
     3361 taggaagggc ctatttagtt ccgtacaaag gtcaagcaca attccaatta ggctataaag
     3421 ggttgattga gttagctcag cgcagcggac aatacaaaaa tattaatgca ggtatcgtct
     3481 ataaatcaca attaatttct tacaaccctt tgttcgagga attaatcctt gactttagca
     3541 agccacaaga tgaaattgta gggtattttg ccgcttttaa acttttaaat ggattcgaga
     3601 aagtttcttt ttggacagta gaaaaagtaa ctgcacatgg aaagaaattt tcaaaatcgt
     3661 ttgctagcgg tccttggaaa acagactttg atgcaatggc tcaaaaaact attttaaaag
     3721 atattttgag taaatatggt ccgttatcag ttgagatgca gaaagctatc gaggaagata
     3781 atcaagattc aacgatttct actccaaaag acatcacccc acaagaaaca aatagtcttg
     3841 atgacttaat tgatcaccag agcgaaaaaa aggacgctcc tagcaattta aaagacgcaa
     3901 gtgaatattt acattcagag ccagaaaaaa cgctcacaga cgaaaataag acggttttag
     3961 aagatacgtc ttatccagca gatgaggttc ccgattttga ccaagagact ggcgaagtat
     4021 tagctagcga aggcaacctc tttgataatc tcggagactt gatgccatga cgaagttaga
     4081 cttgctcgga aaggactatt atagccgtga atcagcgatt aaatactggt ctattagtca
     4141 gtacaagcgt tttagagaat gtgaggcaag ggcgcttgct gaattacgag gggattggac
     4201 agataccaga gataacactg cgctgctcgt cgggaactat gtccactctt actttgagag
     4261 taaagaagct catgaagaat tcaaagccca aaacggctct gaaatgattt cgaccagagg
     4321 aacaaccaaa ggtcagctca aaaaagacta tttagtcgca gaacagatga ttgaagcact
     4381 taaaaatgac agtaacttca tggccatata ccaaggagaa aaagaagcag caatcacagg
     4441 atttcttggc gaggttgaat tcaagggtaa aatcgactgc ttgaatgttg aacgtggcta
     4501 ttttgtagac atcaaaacaa caaaagggcc gattgacgac acaatctgga atggagaaga
     4561 gcgtgtcaga tggtttgaag cttatggata tattttgcag atggctgctt acaaaaacat
     4621 gctagaagct aagtataaca aaccgtttga gccgattatt tatgcagtga ccaaagaaac
     4681 gccgccagac acaagggcta tcagaatcca aagtatagat gctatgcaga tggagttaga
     4741 tagcctagca caaagcatta agcgattaga tgacgttaaa aaagacgtag aaaagcctga
     4801 tccttgcggt cattgcgagt attgtagagc caatcaatta acgcaaagag taatgatttt
     4861 ttaggagata aaaatgacta aatactatgt atcagctaag attgcaaatc tagacatagg
     4921 tgcagaaatc gaagcagaaa atcagcacat ggctccgata gcatttaaag aaacgtacga
     4981 ccatttactt agattcggaa gccataagct gagaatatta ggcgtcgaag aagttaatta
     5041 acaacctatt gcaaagtgaa gctcggcctt tgtaatacca atattttcca agcgagaaag
     5101 gaaagttgga atatcgtcaa attaacagga ttgatgatat gaagaattgc tacactcgtc
     5161 cttgccaatg ctcacacaca attttagggc gagtgtggat tttaagagaa tatatgtatt
     5221 atgaatttgt tttatcaaac acaaaacaga aaaaggaaat gttatcaagc aatgatcgct
     5281 tgcattttag aaaatcagct agtatcacaa aaggattacg acaattagct aaactaaaat
     5341 caaacggact gactaaaaaa cacactaaaa acaatccttg caaagttatc gtgacagtgt
     5401 ttacgccgac aaaacgacga tttgaccctc caaatattta tccgacaata aaagcaattt
     5461 tggacggctt tacggacgct ggtgtttggg atgatgacaa tcacgaaatc ataaaatcac
     5521 tcacgtttag gtatggagga ttaagcaacg taaaagagaa ataccgcatt gcgattgaaa
     5581 ttttagaaat ggagacacat gactactact aaaaaacacg ttgtaagagt ttacaacaaa
     5641 ggtattacag cgacttacat ggtttatgac aaaaaactgt ttaaggagca cgagttcgca
     5701 acaaaaagag aagcaatgca gtttattaga cagctagagt tatctaatga taagcgagcg
     5761 acagaatatt atttgagaga ggtggagaga tgctgacgga agatacgttt aaaaaaaatt
     5821 gaggagcttg aagctgcttg tcaggatacg acagataaca ttaaaaaacc atcacactat
     5881 caaggcaggc atggcatgga agcaatcgat gtggttaaaa acttttcagc ttgtccagag
     5941 cacgaggaag gtttttactg gggcaatgct gttaagtacc ttttgcggta tcacgctaaa
     6001 aatggtgttg aagacctcaa aaaagcacgg cagaaccttg attggttgat taaaaagttg
     6061 gaggaagtgg aatgaagaaa ccaaatcgtt atccgtacag taaatcaaaa tttaatggtt
     6121 gtatttacca gttgtgtgca gccagcttta aagatgaaca atatgtcaaa gatttaaaat
     6181 catgcggcat acattatcaa atcacaaaag ttggtcattt tcctgatgtt tttataaaaa
     6241 ttgataatct cgaacaatta caagcattaa tagataaaac aggacacgat ttaatactta
     6301 gtaaaaacga aatttggatt tatgatgact atatggaatg aggagtaata atgacaacag
     6361 atgaattatt gcaaaattta cgtgatgact tgaataaaat aatgaatgtc ctaaaaaacg
     6421 attggaaagc actattgttt cttgcaatcg caatatttgg gatgatggta accgtgtcgt
     6481 attttagcta tcgcgacgca cgacaatatt acgagtcgca aatcacagga ctacgtacac
     6541 agctaagcag gacacaaaag cagcttaaac gtgctagcga gcaaaatcag agacagacta
     6601 agtggatagc tgagttgacg ggtaatgggg ggtgacatga ttaagatcga tgagatacat
     6661 cgcatactag gcatcgacga agtttataaa gcacccaaac gacttatgga catactcttt
     6721 gataaagata gtcgtgagga tatatttaga cagtttttgg atattgagac agatctatct
     6781 tatgactggt ttatgcgata ttttgaggat gagcatgccg atcgtaaaaa taaaaagcaa
     6841 gattttactc cgctaagtgt atctaagtta ctgactggat tggtaagcgg gcacacatac
     6901 catgagagcg cagtaggcac aggaggaatc ctcatacaag catggcaaag acataggata
     6961 tcatcaaatc cttttacata caaaccaagc gattattggt atcaagtaga ggagttatct
     7021 gatagagcat taccgttttt actctttaat atgtctataa gagggataaa tggtgtggtg
     7081 gtgcatggtg actctttaac aagacaagtt aaaaacattt attttttgca aaatacaaaa
     7141 gacgacatgc tgagttttag tgatattaac gttatgccaa ggactcaaga tattgagcaa
     7201 gaatttaatg tcaaagagtg gattggtgat gcgatagtgc atgtagagag taagttaaat
     7261 gcgaggtaaa aatgaacatt gaagaagcga aaagagcgat aagagaacta gacgcaagcg
     7321 ctcaagagcc tgcaatggct ctgtgggtct acgagctgga atactcgtta aacttaccct
     7381 agaagctttc tgtaagtatt cagctgcgta gcgtgggata atcgttacgt agttatagag
     7441 cgaaattttt agaaagggaa atatcctcct tttttcataa aaatctaaag tctgttatcg
     7501 ctcacagatg attatacaag gcgtcgctaa tgctttaaca cgacatcgta cgcctgtgtc
     7561 aaaaataaaa aaagaaagag agggcttttc tccacaaaaa aagccagctc acagctgact
     7621 ccttggttaa taattcgata aatctattat accaaaaaag gagtaggttg tggctagaaa
     7681 tgagattaca gaagcgcata aaatattaaa agaattgcag atgattccga agatcataaa
     7741 agagctgaaa ttagatatag aacgtacgca agccagcttg ctttctagtc ctcaatggtc
     7801 agatatgcgt gtatctggcg gtgtgagaca atcacagaca gataaaaacg taactattat
     7861 tgacgctaag gattataatc ttgctgagat tgataagcta ttaaaacgca aagaagagat
     7921 attggatatt atcagcaaat tggatgcaga acctagatta ttattaattc gagcttatgt
     7981 cattgagaaa tatcccagcg attgtattga aaaatattac tcagaaaaga aatattacac
     8041 agttaaaagg attgcaattg accagttaaa tgccgtaatt ggacagcaaa tgacagtaca
     8101 cggacagtaa taatgtttta ttatagtatt atcaagaaat gaggggcagg tacgaaaata
     8161 cccccctctt ttaaatttag aaaggctccc tatgtctcaa ttaagggcag ataaaaaagg
     8221 tacccaccgg gcagcgtttg acaggaataa gaagaagctg ctgaagacag ccactatctg
     8281 tggtatctgt ggtaagttag tggataagtc gctgaagtat ccacatccat taagcgcagc
     8341 aatagatcat atagttccta tcgcaaaagg tggtcatcca tcagcgcttg agaacttaca
     8401 gttaactcac tggcagtgca acaggcagaa gtctgataag ttgtttgcta accaagcaag
     8461 caacgagcca aagacaattg gcaacagaaa ccttcctcaa agtcgagact ggtcatcttt
     8521 tgcatttaaa aagtgatttt aggcaaatat attgatttat actaaaagct cttagaagag
     8581 aaatgggggg tatctcccta cctggtcggt cggccgagct tcacgccgtc actgtacatt
     8641 ttttctcacg ttaggattta gaaaattttg gaggttgaat tttgttgaaa aagaaatgct
     8701 taatttgcaa aaaaaacttc caagcaaaaa ccaatagaac tttatattgc tctgaagaat
     8761 gccgtaagaa aggcaatcgt gagaaacaac gtaaattgat gaaacaaaaa cgggctgaac
     8821 agaggaaaga aaaaaagaaa gtcctaaatc ctaacacaga tgtgacagaa aagcctaaaa
     8881 aaatacgtaa tttagcgcag cactataaaa aactaaaaaa ggaaattttg gcaaatgaat
     8941 ctgaatttgg ttttactgga ataacactta ttgaaggaat agatgtacat gaagaaaact
     9001 ttgtagattt agtcatgcaa aaaataaagg agcagaaatg aattatatgg gtatgggcta
     9061 tcttcgtagg aagttagctc tttttaaaac tggagttgat aaaagatatc gttattatgc
     9121 catggatgac agagacgaca cacgaagtat tgtcatgcca aataatgtgc gtgaaatgta
     9181 caggtctgtg ttagaatgga ccgctaaagg ggttgatagt cttgcggacc gtattatttt
     9241 cagggagttt gccaacgatg attttaatgc ttgggaaatt tttaaagcga ataaccctga
     9301 tatctttttt gatacagcca tacagtcagc attaattgca tcttgttgct ttgtgtacat
     9361 catgccagga gcggaagacg gcttacctaa aatgcaagtt atcgaagcta gtaaagcgac
     9421 ggggatactt gacccaacta catttttatt aacagagggt tatgcaattt tagagtctga
     9481 ctcaaacggt aatcctacgt tagaggccta tttcacagac aaagacatct ggtattatcc
     9541 aaaaaaaggg aaaccatata atattaaaaa tccaacaggt caccccttgc ttgtacctat
     9601 cattcacaga ccagacgcag ttagaccatt tggtcgcagt cgcattacca aggctggaat
     9661 gtatcatcaa aaggcagcga agagaacgct tgagagagca gaggttacgg ctgagtttta
     9721 ctcattccca caaaaatatg ttttgggaat ggatccagac gctgaaccga tggaaaagtg
     9781 gcgtgccacg gtatccacat tgttggaaat ctcaaaagat gaagacggag ataagccaac
     9841 tgttggtcag tttactacag ccagtatgtc tcctttcatg gagcatttaa aaatgtatgc
     9901 ttccctattc gctggtggtt ctggactcac tcttgatgat cttggttttc catctgacaa
     9961 tccatcatca gtagaagcta ttaaagcagc gcatgaaaat ttaagagcag caggacgtaa
    10021 agctcaacgc tcttttgctt ctggatttct aaatgtggcg tatattgctg tttgtttaag
    10081 ggatgagttt ccttatttac gcaatcagtt catggatact gaaattaaat gggaacctct
    10141 ttttgaagct gatgcaaata tgcttacttt agtcggtgat ggcgctatta agcttaatca
    10201 agctattcct ggtttcatgg atgcagatgt tatccgtgac ttaactgggg taaaaggttc
    10261 tgacaatcca actccaaaag cgacggaggt gacaactgat ggctgatgat gtcttaccta
    10321 agattttaaa atcagttcaa caggattttg aaaagtattt tggtaaaagc gaggtcgttg
    10381 ctaaggcttt tgcagatttg aagtctaaaa aagcaacata taaaacagtc aacgagtttg
    10441 gtattgaagt tggaaaactt ttatctttgg ctctgacagg ctctattacc tcggataaat
    10501 taccagacgg taaaatgtat tacaatatcg ctaagcgtct cttagatgag actatgggac
    10561 ggaattacaa attgatttca ggttatgctg gtgatgttca gcggatttta aatgagaatg
    10621 ctcagattgg tctaaaggtg caacgtccac cgctaaatcg agacaagatt aacgggatgg
    10681 taaatcgttt ggatagcgag aatacatttg atgatgtaaa atggctgttt ggtgaaccga
    10741 tcgttaattt ttcgcagtcc attgtggatg ataccatcaa ggcaaatgcg gatttacaat
    10801 ataaaacagg tatgacgcca caggttgtca gaacagaaag tggcaactgt tgtgaatggt
    10861 gtcgtgaggt tgttggcact tatagttatc caaaagtccc taaggacgta tggagaagac
    10921 atcagcggtg tcgatgtacg cttgactatg acccgaagaa tggaaaagtt cagagtgctt
    10981 ggagtaaaat ctggcgaaag aaagaaaaaa ctcaagaatc tatagaaagg gttgaaaaat
    11041 ttaaggaaag tgctctagta gaatctatca aaaatgatat cgctaagtta gatatgacaa
    11101 aggttggtcc gagtgatata attgatatag ggaaacgtat caattatcac tttagagttt
    11161 cagaacatat aggagataaa gagaaattaa aagaaatttt ctcaaatttt cgtgaaatcg
    11221 gtggagaaat acctaaaaat acttgggcaa aaggttcatc taaacttgtt aaagaccagc
    11281 tacaagaggc ttttcaaaat tatccaactg agtgggcagc tgttccggac ggtattggta
    11341 aaaaactaaa agctataaaa aggaagcgcg gttacttcga tggatatgat gaagatttag
    11401 ttattgctac aaatggaaca agaaaaacaa caccttacca tgagatagga catatgattg
    11461 aactggttaa tcctgattta gtaagattag agaaagcttg ggtagataaa agaactgcta
    11521 atgaagctga ggttcgcttg aaagatattt ttccaagttc aaattatggt attggggaag
    11581 ttactaagaa agatgacttt atatcaccat atattggtaa atactacagc gatgcagctg
    11641 aagttttcac tatgggatta caaggtattt ttgttcctga agaacgattt gctaagtcct
    11701 ttgacaaaaa aacatggaaa tatgactaca agacaatcaa tgacgaccct gaatttttga
    11761 attttattat tggattattt gtgaaagtgt gataaatatg gaaccaaaat tacatcggca
    11821 actgcgtcaa aaatatgacg acgctgaaaa acaatatctt gaaaagtttg gagaagactc
    11881 gcttgataga gtattttttt gggagccaga cgtttacttt gatgagtgga aaaaggttct
    11941 accagatgca acactggaat taaacaaagc tattaatagc ggggtggcga ttgatccaga
    12001 tccagaaaac gcaatatatt aagcacctag agcaatctgg tgcttttctt atgcccaaaa
    12061 aggagaaaaa tatgaataaa atatcattaa atgtcgaaat gacttgggaa aacaaagacg
    12121 aatttcaaca aatcatgaat aaagtcaatg aaacaaaaga agcttacgaa aaagccttag
    12181 aagctgcgga aaattttgtc cctaaaatgt cgtgtgcaac aaagttaaat aaaggagaag
    12241 gcgatgaata agcgaatcaa aaagaaacgt aaactcgaac gggctattgt gatgctggtt
    12301 gcggaaaatg ctatgcaagc agaagcaatt aaaaatcaaa acaaagaaat catggagcta
    12361 aaatcaatcg ttcaacgaaa cgctctggca acaaacgaag agtttgcgtc tgttaaagct
    12421 gctactttag ataaccaatc agctattgca gatattgcaa ttgacgttaa ctatattaag
    12481 aaaaattaca agcgaaaatg gggaaaataa attttaaacg aattcgaccc ctttagaaat
    12541 caaagtcgta gcaatacggc tttttattgt gccctgtcgc atggctaaaa actaggcagt
    12601 acgattgaaa ggaataagta tggttactaa gacgaaaaca aagcttggca atcagcgacc
    12661 tactcaatcg gtaaatttac attttgctaa atctctagcg catgaagcta ttaattacta
    12721 caaaaaaaca gggctaagct gctatccatg gcaagtaaat atgcttatcc caattatggc
    12781 catagatgaa aatggtctgt gggttcatca aaagtatggg tatgctatcc cacggcgtaa
    12841 cggtaagacg gaagtagtct atattgttga gctgtgggct ttgcataaag gtttaaaaat
    12901 cttgcataca gctcatcgaa ttagcacatc tcacgcatca tttgagaagg tgaaaaaata
    12961 ccttgagatg tcaggttatg ttgatggaga agactttata tcaaataaag ccaagggtca
    13021 agagcgtata gagttcaaag ccagcggcgc tgttatccag ttccgaacta ggacatcaaa
    13081 cggtggactt ggtgagggat ttgacttact tatcattgac gaggcacaag aatacacatc
    13141 tgagcaagaa tcagcattga agtacacagt tactgatagt gataatccaa tgactattat
    13201 gtgtggaacg ccgccaacga tggtatctac tggtacagta tttgaagcat atcggaaaga
    13261 ttgcttaaaa ggcaataagc gttattctgg ttgggctgaa tggtcagttc ctgagatggt
    13321 taagattaac gatgtatctt cctggtatat ttccaaccca tctatgggat tccacctcaa
    13381 cgagaggaaa atcgaagctg aattaggtga agatgagatt gaccacaata tccagcgttt
    13441 aggttactgg ccatccttta accaaaaatc agttatatcc gaaaaagaat gggcaaaact
    13501 caaagttgag caagtgccag aactcaaaag caagcttttt gtcggtatca agtttggtca
    13561 agatggcaac aacgtatcac tatcaattgc agcaagaaca tcagaaaata aggtatttgt
    13621 tgagactatt gactgtttat cagttaggaa tggtactcaa tggattatta attttctgaa
    13681 atcagctgac attgctaagg ttgtcattga tggtgcaagt ggtcaagaat tacttgctca
    13741 ggagatgaaa gatcaaggtc taaagaaacc agaattgcct aaagttgctg aaattatcac
    13801 agctaacatg atgtgggagc aggggatcat gcaggaaacc atttgtcata gtgatcagcc
    13861 atctttgaca gcagtagtca caaactgtga aaagaggcaa attggctcta atggtggttt
    13921 tgggtataaa tcgctttatg atgatagaga cattagctta atggacagtg cattgcttgc
    13981 gcactggatt tgttacacaa cgaagccaaa aagaaagcaa agaaccagct gttaaaaaac
    14041 gacatccgaa agggtgtttt tttactgcta aaaaatctac cgaactgtcg ggaaagcagg
    14101 agaaaggacg ttaatatgtc agaatttaaa gttattgaaa aacaagaaga gttggacacg
    14161 attgtgaaag ctcgcattgc tcgagaacgt gagaaatatc aagattacga ccaactgaaa
    14221 actcgtgttg aagaactaga aaccgaaaac agcagcttac aaactgcttt gaatgatgct
    14281 aaatcaaaca ctgatagcta tacggaagag attagcaccc tgaagaatca aattgccgat
    14341 tatgagacgg caaatttacg gacaaaggta gcgttacagt atggcttacc gattgattta
    14401 gctgatcgtt tgcaaggaga tgatgaagat ggactcaaag tagatgcaga acgcttagca
    14461 tcctttatta agccatccca accacaaccg ccagcaaaat caaacgaacc aaatatcgat
    14521 agtaatgcag acgcaaatta cagagcgtta gtgcaaggat taagtacaga agattagaag
    14581 attaattaaa ggagaaaaaa tatgggaaca gaaacatcaa aagcgagctt atttgacaaa
    14641 catttagtat cagatcttat caataaagtt aaggggcata gctcactagc taaactatct
    14701 agccaaaaac ctattccgtt taacggatct aaagaattta cgtttacatt agattctgat
    14761 attgatgtgg ttgctgaaaa cggtaaaaaa acacacggtg gcttatcgct agagcctgtt
    14821 actatcgtac caatcaaggt tgagtatggt gctcgtcttt ctgatgaatt tttatatgca
    14881 acagaagagg aaaagattga tattttgaaa gcttttaacg aagggtttgc gaaaaaactc
    14941 gctcgtggta ttgacctaat ggcgatgcat ggtatcaatc cacgtacaaa aaaagcgtct
    15001 gacgttatcg gcacgaatca ctttgatagt aaagtgacgc aagtggttaa atttacagag
    15061 agcgaagacg ctgatgcaaa tatcgaagca gctgttaatc taattcaggg ggctgaaggt
    15121 gtagtgacag ggcttgcgat ggatacagag ttttcaacag cactggcgaa agttaccaat
    15181 ggggagatgg ggcctaaaat gtaccctgaa cttgcttggg gagcggatcc agatagcatc
    15241 aatggcttga aatcgtccgt caatactact gttggtgctg gagctgatga agcagaatcc
    15301 aaagatttag taattattgg cgattttgaa agcatgttta agtggggtta tgcaaaacaa
    15361 attccaatgg aaatcattaa atacggtgat cctgataatt cggggaaaga ccttaaaggg
    15421 tataaccaaa tttacttacg tgctgaggcg tatatcggct ggggtatttt ggacgctaag
    15481 agctttgctc gtgtcactaa aggagaagta taatgttata cgttaacagt aagactggag
    15541 ctagttttta tagctccgtc cctgtttgtg gtggagattg gactttggtt gaacagcaga
    15601 caggcgaaaa agcaaaaaca gtagcagaaa ttaaacgtca gttagatgct gctgggataa
    15661 aatatagctc taaagctaag aaacctgaat tagaggcact cttgcctggt taggaggtaa
    15721 aagtgggcaa ttttgcaaca acagatgacg tcattttgtt atggcgtccc ttatctgttg
    15781 acgaattgaa acgtgcaaat gcactcttga aagtcgtatc agatacatta agaatggaag
    15841 ctgacaaagt tggcaaagac ttagataaaa cgatggttga taagccttat tttgttaatg
    15901 ttattaaatc ggttacggtt gacattgtag ctagaacact catgacatct actcaaggcg
    15961 aaccaatgac tcaagagagt caatctgccc ttggctatac atggtcaggt tcctatttgg
    16021 ttcctggagg aggtcttttt attaaagaca gtgagttgaa gcgccttgga ctaaaaaaac
    16081 aacgatatgg aggaattgag ctttatggcg aaattgaaag ggataacagt tgctttagtc
    16141 gataagtcga ttagcgaaaa agaccctttt ggaaatcctg taacagttga tttcgatatc
    16201 aaaattgaga atgtgcttgt tacaccagca actaccgaag atatcactaa tcagctatct
    16261 ttaactggaa aaaaggttga atatgtcttg gctataccaa aaggagacga acacgattgg
    16321 gaaaataagg aagttagatt ttttggcaaa aaatggcgca cagtaggagt ccccctagaa
    16381 ggtattgaag agcttatacc actagactgg aataagaaag ttatggtgga aagatatgag
    16441 taagtttaaa ttcaagctta atagaactgg tgttgccgaa ttgatgaaat catcagaaat
    16501 gcagcaggta ttaaccacta aggccacagc catcagagaa cgttgtggtg atggttatgt
    16561 ccaagatatc catgttggga aaaatagggc taatgccatg gtcagtacta aaaccataaa
    16621 ggccaagaaa gataactcaa aaaataacac actgttgaag gcggtgcgat gattgattga
    16681 agtaattatc aaaaaatatt tagacgagca cttagatgtg ccgtcttttt ttgaacatca
    16741 aaaagatgaa cctgcacgat tcatcatctt agaaaagact agtggggcta agcaaaatca
    16801 tttgctaagt tccacgtttg cttttcaaag ttatgctgaa tcgttgtatg aggcggcttt
    16861 acttaatgac aaagtaaagc aagtaattga gcagcttgat gtcttgccac aagtttctgg
    16921 tgtacatctt aacgctgact acaattttac agatacagca actaagcgtt atcgctatca
    16981 agctgtattt gacattaatc actattaaca aaaggagata ataatggcaa atgatactaa
    17041 aaatgtgaca tctgcaaaac caaaggcagg gggagcgatt tattcggcgc cactcggcgc
    17101 taaattgccc gaggatgcaa aatcagaatt agatactaaa tttaagaatt tgggttatgt
    17161 atccgaggat ggtgtggtca atgaagatac acgctcatct gaaaatatta aagcgtgggg
    17221 tggagatatt gttggatctg tgcagacaga aaaagaggat aaatttactt ataagctgat
    17281 tgagtcacta aatgtagaag tcttaaaaga agtttatggc gctgccaatg ttactggaga
    17341 tttaagtggg ggaatccaga ttaaatcaaa ttcaaaagag ttagaagctc acgtaattgt
    17401 tgttgacatg atcatgaatg gcggcattct taaacgaatt gtcttaccaa atgcaaaagt
    17461 cgatgaggta ggtgaaatta agtatgttga cggcgaagtc gttggttatg aaacaacact
    17521 aaaatgtttc ccggacaagg atggtgatac acaccgtgag tatattgtaa aacctggaga
    17581 agctaataaa aaagaaaaca gctttgaaat gtaaagggga gtaaatggaa atcttaaaag
    17641 gaaaaacaac atcaggattt gaatacgaaa ttcctaaaaa acgattaaaa aactttgaac
    17701 ttgttgaagc tattgcagaa gaggaaactg atccaacagc agtagttaaa atcgttaatt
    17761 tgttacttgg tgatgctgct aagtctctaa aagaacatgt acgagatgca gaaggtatcg
    17821 tagatgttga agctatcgga gtagaaatca aagaaatttt tgaaagtcaa aaagatttaa
    17881 aaaactagca atcctcgctc agatgatagt aaaagatgat gatgcgttaa cttgtgattt
    17941 agctgaaacc tacggcatat atgattacaa aaagctacct gcttatcagg tggctgtttt
    18001 tgctgtcggt ttgaggtcta actctaggat aaaaatggca ttatctggag agactgaggc
    18061 tttggatact gttttgttag ctggtattta cgataatact aatttgctgt tttggtctaa
    18121 aactaaggat ggtcaatctg gtcaaaacaa acctaaatca atggttgaag ctctatctgg
    18181 atctaaatca caaaaagcta atgaagtcat ttcttttgcg tctggcgagg attttgcaaa
    18241 tgcacgtaaa caattactag gaggtgatgg ctaatggcaa cagaacttgg tcaagcgtat
    18301 gtgcaaatta tgccatccgc tcgtggaata agtggagcaa tctcgaagca acttgatccc
    18361 gaagcaaggt cggctggttt gagcgctggt tcgctcattg gtggtaatct cgttaaaatg
    18421 attggtggtg ccattgcagc tgctggaatc ggtaagatga tttcgtctgc cttgtccgct
    18481 ggtgctgatt tgcagcaatc ttttggtggt attgacacat tgtataaggg cgctgagact
    18541 gctgtcaaag ggtttgctaa agaggcatac aaagctggaa tatcagcaaa tacttatgca
    18601 gagcaagcag tttcaatggg tgcatctcta aagcaatcac ttggaggtga tgctgtcgcg
    18661 gctgccaagg ctgctaacat ggcaatcatg gatatggccg acaactcggc taagatgggt
    18721 actgatatca catcaatcca aatggcttac cagggatttg ctaagcaaaa ctatacaatg
    18781 cttgataacc taagacttgg gtacggcggc acaaaagaag agatgaagcg tcttttatca
    18841 gacgctgaaa agttacctgc cgctatgggc aagaagtttg atttgagtaa ttatgctgat
    18901 gtggttgagg ctatacactt ggtacaggat aacatgggta tcgctggagt tgctgctgaa
    18961 gaagcaaaaa ctacattttc aggctcacta gctgctatga agtcctcttt tacaaatgta
    19021 atggcaggtt tatcactagg agatgatatc agaccggctt tacgaggact ggctgagaca
    19081 acttctaatt tcttatttgg taactttatt ccgatggtgg caaatatctt taaaggatta
    19141 ccatcggcaa ttggtacttt tattggagcc gcagctccta ttatcacaag tcaattccaa
    19201 ggtctaatga gtagccttgg aattagtatt gatttaagtc ctattactgc taaatttgca
    19261 cagattggcc aaaatttaca acctgttttt aacggtttaa aaaccgcttt tgggcagctg
    19321 ccatcatttt ttactagcat cggtaatgca gttgcaccag tgatagacac tattatcagt
    19381 ggattagcta gattagattt tagtggattc caatctctta tttcagcaat tttgccagca
    19441 ttgcaagcag ggtttcaaac attcatggct attgtaggtc cagcgattag tcagcttgta
    19501 aatagctttg ttaatctttg gaatgcttgc caacctctag taacaatatt aagcggcgca
    19561 ttgatgccag cctttcaaat tttaggagct tttctcggcg gagtcttaca agggattctt
    19621 ggcagtatta gctttgcatt tgatgcttta aaagttgttg ttgaattttt aacaccaatt
    19681 attgattggc ttgttcaggg attcaatgca attgctccag cgttacaaat tggagcacag
    19741 tggatcggtt atattattgg tatgtttacc agcttaggtg catctggaca aggtttaagc
    19801 agcatattaa gcagtgcttg gggtaatatc aaaacagtag tttcgacagc taaaaatatg
    19861 ataactttgg cgattgatgg cattaaattg gtatttagta atttaggtaa tgctggcaat
    19921 attttaaaag gattactttc ggcagcatgg tcagctatgc aaaatgcagt agtgatagcc
    19981 aaaggcgtaa tcaatggtgc aataagcgct ataaaaacag catttagcag ctttggtaat
    20041 cttgtatcta gcgtaagtgg cacaataaaa gctgttatcg gaagtttaaa aaatgttttt
    20101 tatagtttag caagtattga cttagttggt gcaggacgtg caatcatgca aggatttcta
    20161 aacgggctaa aatcgatgtg gggggccatt acaggctttg ttggtggtat cgctgactgg
    20221 attcgtaagc acaaaggacc tatctcatat gataaggtct tgctaaaacc tgctggtaaa
    20281 gtaatcatgc aaggatttaa tactagcttg atggacgggt tcaaagaagt taaatcaaat
    20341 gtctctggta tggctgatga ccttgcagga acgatgacag gtaaaagttt atctcttggc
    20401 attgatgcta aaccaagcgt cactgctgac gacttgctat cgagtaacac tagctctaag
    20461 tctacaatcg gttctaccac aagtgacttg tcattgttct ttgttaaggt acttgctcta
    20521 ttgcaagata ttcttgacaa aaacacagat gtctatttag acaaagaaaa agtcagcgcc
    20581 attttatacg aagagtttgc caaaattatg gctagagaga ggattgtatg ataccaaagg
    20641 ttattattga tgattttgat acgtctacaa tccctaattg tgttttgacc ggttacgatg
    20701 taggggacat tttatcccct agttttgttg aaaatgaagt ctatggcatg aatggaacaa
    20761 atagagaatt agaatcatac aatgaatcta aacctacatt atcatggcat ttaaatagct
    20821 ttgatgatgc tgttaatcta gttaatcgtt tagacggcct tagtaaaaaa atcgaatttt
    20881 ggcacatacc taactctttt tattactatg attgcctatc tgtcaaaatc aatgctgtga
    20941 atatgaaatc gtggagggtg actctcaaac ttgctcttta tccatttaga tacgcaaaag
    21001 gtatctcaga tgtcacaatc acaggcaacg gaaacattaa caatacagga aatgttttca
    21061 gtgaacccaa gatagttgtt gagggtactg gaaaaggaac gctaacaatc ggcaaacaag
    21121 ttatggaatt aaatttgtca ggtaaagcaa cgatcgaatg caaacatggt caacaatgtg
    21181 tttatgatac tggaggcaat gtgaaaaact caatccgaat aagaggcagt ttttttgaga
    21241 tacaacccgg tacgcaaggt atcgctgtta gcggtggcat tactaggtta acaatcagtc
    21301 caagatggag gtacaaagtt tgatatcaat taaagatgat aatacccctc ttgtggctgc
    21361 ctttgaggac gaaatcagcc aggaagctaa tagtgattac aaactaagtt ttaagtatcc
    21421 cgctaaacac gattaccgtc ctttgatcaa aaaaggaata atcctagaag ctgatgatct
    21481 acatggaact cagctcttta gggtttttga aattactaag cgtcatggct acattaatgt
    21541 ttatgctaat cagattgccg atgacttaaa tggctatgca attaactcta ttagtgttga
    21601 tagagtacag ggcatgaaag ttatgtccga gcttgcaggc agcatcaagc gagatcaccc
    21661 atttagcttt tttagtgata ttgatggccg gcatacattt aatcaatcag atgtatctgt
    21721 tatggatgct ctggccaatg gcaagcactc agttatgggt caatggggtg gcgaacttgt
    21781 acgtgataag taccaggtta atttactcaa aaaagctggc aaagataccg aagctctttt
    21841 tatgtacaag aaaaacctca aatcttatga ggaaacggat actatcaaag gacttatctc
    21901 aatactgcac cttgttgcag aagtagaaga agagcatgaa ggagaagcca gagaagcttc
    21961 agatggaaac attggtcata gtgaatcacc gaaaaagaaa acgattaggg cgactgttga
    22021 gagtaagctc aaagacactc atccgataat tgtcgaaaag tctatcaagg tgcaggatca
    22081 agatgtcaaa acagaagagg acttgcttgc atatggtaag aaatactttg aaagtacact
    22141 ctgcgatata ccaggcaata gtttaaaaat tgatgttact aataactacg agggcaatgt
    22201 taggctattt gatacagcaa ttgttttcca cgaactctat gatagagact tacggatgca
    22261 aattaccgga tacaagttcg cccctatggc taatcggttg aaatctatta gttttggaga
    22321 gattaaaact aatttagcaa agcaaattag cagtcaaatt gataataagg tggctgaagc
    22381 aactgctcaa catgatgcag catttgaagc taaattacaa aagcaaatcg aaaacgctga
    22441 tcgtgtcttt gatactaaag aagctaaact ccgtaaagaa attgaagatg gtatcaaaaa
    22501 agctgaagct aatgctgaag tcaaggttgc tgaggttaat gctaaagtgc tggaagccga
    22561 gaagatagcc aaggaagttg atgagcggct caaaaaattt ttagctagtg ctgatgctaa
    22621 agagcaagat tttgataaaa aacttgaaga atttagaacg tctcttaaag accttgaagt
    22681 cgatgaaaag cagattgatg atgctttggc caaagccggt tttagcaagg atagcttagc
    22741 tgacattaaa gctaaactgg aagacacgtc tgaaactgcc acagttacag ctaacattgt
    22801 tggatcaact ggcggcacgt tttacaatcg caacagactg gatggtgata ctgacaaagt
    22861 tatcactttt gaacaaggtt atattgacat tgcccataat ggtgaaggtt ttgaagaagg
    22921 caagacatac actatcagct ttgaggcaac ctgcgagcta ctgcgtaaag taggaatcac
    22981 agtgacacag gctaacatga aaggtgctcg cttagtgtta acacctaaaa atcccaaatt
    23041 agttgtcgag agttttggct tgactaagga tactgagact atcaatgtct atccgtttag
    23101 ctacacagtg cttgtaacca gcgactggta taaatctaag caaatagatt taaacgcgtc
    23161 ggaggtgcag gaattggccc ttgagatggc ttataaagat gtggttgacg gtaataatgc
    23221 cacgatagca gggcagtggt cagacagccc gcaaattata ttagacggag gtaaaaaatg
    23281 agtgaaaata taccgctgcg agtccaattt aagcggatga aagccgccga gtgggcaagt
    23341 agtgatgtcg tcttactgga gggtgagatt ggctttgaga ctgacactgg ttttgctaag
    23401 tttggcgatg gtcaaaacac ttttagtaag cttaagtacc ttactggtcc caaaggtcct
    23461 aaaggagaca ctggtatcca aggtaaaact ggaggaactg gtcctcgggg ccctgctggc
    23521 aagcctggaa cgacagatta tgatcaactc caaaataaac cagatctagg tgcgtttgca
    23581 caaaaagaag aaactaatag taaaatcacc aaattagaat caagcaaagc agataaaagc
    23641 gctgtttact caaaagcaga gtcaaaaata gagctagaca aaaaattgag cttaacaggc
    23701 ggcatagtga caggacaact acggcttaaa cctaatagtg gtattaaacc ctcatcttcc
    23761 gtaggaggag cgattaacat tgatatgtct aaatcggaag gtgctggtgt tgttgtctat
    23821 tctaacaatg ataccagtga tgggccgtta atgagcttgc ggacgggtaa agagaccttc
    23881 gataaatcgg cgctttttgt cgattacagc ggtaagacta atgccgttaa tattgcgatg
    23941 cgccagccaa gcacacctaa tttttcctct gcgcttaata ttactagcgg caatgaaaat
    24001 ggtagtgcga tgcagctacg agggtcagaa aaagcgctag gaacgctcaa aatcacacac
    24061 gaaaacccaa gcgctaacgc aaaatacgat gaaaacgctg cagcgttatc tattgatatc
    24121 gttggaaaac ggggagccag tggaaatggt actgctgccc aaggcatttt catcaattcg
    24181 tccgcaggca caactggtaa aatgctcaga atcagaaata aaaatgtaga caaattttat
    24241 gtaggtccag atggtggctt ttggtcatgt gcaaattcaa ctgtagctgg taatctaaca
    24301 gttaacgatc caacatctag caaacatgct gtgactaaag attacgtaga taaagaaatt
    24361 gctaagttaa aagaactcat acaaaaaaaa tagattaagg aggataaatg agcagagatc
    24421 caacttatac aatcaacgag cacgacttat cttttaaaga tggtcgtttt tatgtgactt
    24481 ttagagcaga taagtctagc gagactgtca gacttaatag tagctgtctt ggcaatactg
    24541 tcatcaaaag gctacaagtt gaggatgacg agactatgca tgattttgtt aagcctaaag
    24601 tcaccactca gcaacctttt ggcttagcca agcaagtaaa agaaattgat ttagagctta
    24661 aagatcctaa gtccgattta tggggaagaa ttaaagccaa taacaaagct atgcttgttg
    24721 agtatggcaa caaagaaata gccagcgcca ttgcgcaatc agccgaaaaa attttaacgc
    24781 aagttaaatc gcttgatgat gagcggtatt ccaaatttga gcaaacccta gaaggtatca
    24841 agcaaactgt caaaagtgaa tcggtggaat ctgcaaggac tcagctagca tcaatgtttg
    24901 atagtcgtat taccaggctt gacggtaagt atagccgtct cactcaaacg ctggatagtt
    24961 tatctactcg cttggatgac ggacttggta actactctac gcttagccaa aaaatcggag
    25021 gtgtggaaag ccgtgtcagt agcctatcgg gtaatgtctc acgcttttcg cagacagcgc
    25081 aaggcctaca gtctcagatt acagatgcta gtcaaaatta cagtagacta tcacaaaccg
    25141 tgcaaggcat ccagacaact gttagagaca atcaaacagg tacagccagc cgtatcaggc
    25201 agctaagtga cttaatcagc actaaagtga ctaagggtga tgttgagaca actattgctc
    25261 aaagttacga caagatagct ttggcgatta aggacaagtt gcctaagagc aagatgactg
    25321 gtaatgagat agtctcagcg attaaccttg ataggtctgg tgttaaaatc actggtaaaa
    25381 acatcactct tgacggtaat agctacatca gcaatgccgt gatcaaaaat gctcatattg
    25441 ctaacatgga cgccggtaag attaacacag ggtacttgag tgctaatagg attgcggccg
    25501 aggctatcac tggtgacaaa atcaagatgg actatgcctt ttttaataag ctaactgcca
    25561 atgagggata ttttaggacg ttgtttgcta aagacatctt tgcaacatca gtccaatctg
    25621 taacactatc agctagcaaa attactggag gtgtattagc cgctacaaat ggggcaagtc
    25681 agtgggacct aaataatgcc aatatgacct ttaatcgaga tgccacaatt aattttaata
    25741 gcaaaaacaa tgccttagta cgtaaagatg gcacacatac tgcctttgta cattttagta
    25801 atgcgacgcc aaaaggctat agaggctcag cgttgtatgc ctctatcggg ataacctcgt
    25861 ctggtgacgg gattaacagc gcgtccagcg gtcgttttgc aggactaagg tcatttaggt
    25921 acgctacggg atataatcat actgctgcag tcgaccaaac cgagctatac ggtgataatg
    25981 tcttgattgc agatgacttt agcatcaatc gaggatttaa atttagacca gacaaaatgg
    26041 aaaaagtgct cgacatgaac gacttgtatg cggctgtagt agccttaggc cgctgttggg
    26101 ggcacttggc taacgtcggc tggaatactg ctcatagcaa ttttacaagt gctgtgaata
    26161 gggaattgaa taactacatc acaaaaattt aacaggagat aatatgcaat taactattaa
    26221 aaacaaagat ttaaacacac tatatcgtgt actagacaaa atcaaggtta ctaatatgcg
    26281 tgctaatcgt ggccgtgcta agctacttgc aaaagtcgag ggcaagctaa gcgagtatgc
    26341 caaagatgag gttgatatta ttgaccagta tgttgcaaaa aatgacgatg gcaagtggat
    26401 tacagatgac aaaggtaatt caaaaattga ggatacctca aagttagctg agcttaacga
    26461 ctttttagac gagttagcaa gcgagcctat cgtcatcaaa ggtggcgagt actctaagcg
    26521 ctttatcgat tttttggaat atctagccga atctgaagat gagtttacag ctcaagaaat
    26581 cattattgtt gacagcatct tagagcaata cgaaggaagc aaaggagaat aactatgaag
    26641 acattaacac tatcaggcaa accttatcca attcatgaag gcggtaaagt tgtaaaaaca
    26701 gaggttcgct taatcggtga caatgggcta tttatcccca ttgaattaat cggtgatcag
    26761 acagctaagg gagcagatga ccttattaaa gagggactag atgcttttgt acgcgagtat
    26821 gtgactaaat acgccgtagc agaatcagtg caaaaagtgg aagagttgag cctcgcacaa
    26881 aaagagattg agcaaaatgc ggagcaagca aaggtaacag cagaagccgc tgaaaaacaa
    26941 gctaaatctc tggagcttgt cattgcaaaa tctcaaaaaa tggctaatct acaagctatc
    27001 catctactaa caagcggaag caaagttgag cctgatattt acaaaggcat gttagagcta
    27061 atcgagcctg tcaaaaaagg taagtatcaa gcctatgatg tctttacggt ggtcgacgat
    27121 aaacacgaag acgaagctgg tgaaggaaac ctagtctttg tacatgtcaa tgaaccgttt
    27181 acttatgagg cgcagacctt agaggagcta gaggaagagg acaaagtaac ggt
//
LOCUS       DAUNLR010000023        25160 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUNLR010000023 DAUNLR010000000
VERSION     DAUNLR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25160
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.023"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            101..1099
                     /gene="ruvB"
                     /locus_tag="VLL59_000975"
     CDS             101..1099
                     /gene="ruvB"
                     /locus_tag="VLL59_000975"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HER6509105.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            1237..1674
                     /locus_tag="VLL59_000976"
     CDS             1237..1674
                     /locus_tag="VLL59_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HER6509106.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRAISDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            1697..2098
                     /locus_tag="VLL59_000977"
     CDS             1697..2098
                     /locus_tag="VLL59_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509107.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            2095..3870
                     /locus_tag="VLL59_000978"
     CDS             2095..3870
                     /locus_tag="VLL59_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HER6509108.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLFWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMVGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLIQGRKPNLLGLEIDCSPYYKWIVGGALALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            4179..6821
                     /gene="adhE"
                     /locus_tag="VLL59_000979"
                     /gene_synonym="adhC"
     CDS             4179..6821
                     /gene="adhE"
                     /locus_tag="VLL59_000979"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HER6509109.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            7073..8089
                     /gene="adhP"
                     /locus_tag="VLL59_000980"
     CDS             7073..8089
                     /gene="adhP"
                     /locus_tag="VLL59_000980"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HER6509110.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTAEYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            8477..9766
                     /locus_tag="VLL59_000981"
     CDS             8477..9766
                     /locus_tag="VLL59_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HER6509111.1"
                     /translation="MIYSRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            9965..10273
                     /gene="rpsJ"
                     /locus_tag="VLL59_000982"
     CDS             9965..10273
                     /gene="rpsJ"
                     /locus_tag="VLL59_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HER6509112.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            10521..11147
                     /gene="rplC"
                     /locus_tag="VLL59_000983"
     CDS             10521..11147
                     /gene="rplC"
                     /locus_tag="VLL59_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HER6509113.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            11171..11794
                     /gene="rplD"
                     /locus_tag="VLL59_000984"
     CDS             11171..11794
                     /gene="rplD"
                     /locus_tag="VLL59_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HER6509114.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            11794..12090
                     /locus_tag="VLL59_000985"
     CDS             11794..12090
                     /locus_tag="VLL59_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HER6509115.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            12108..12941
                     /gene="rplB"
                     /locus_tag="VLL59_000986"
     CDS             12108..12941
                     /gene="rplB"
                     /locus_tag="VLL59_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HER6509116.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            13079..13357
                     /gene="rpsS"
                     /locus_tag="VLL59_000987"
     CDS             13079..13357
                     /gene="rpsS"
                     /locus_tag="VLL59_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HER6509117.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            13373..13717
                     /gene="rplV"
                     /locus_tag="VLL59_000988"
     CDS             13373..13717
                     /gene="rplV"
                     /locus_tag="VLL59_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HER6509118.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            13730..14383
                     /gene="rpsC"
                     /locus_tag="VLL59_000989"
     CDS             13730..14383
                     /gene="rpsC"
                     /locus_tag="VLL59_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HER6509119.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            14387..14800
                     /gene="rplP"
                     /locus_tag="VLL59_000990"
     CDS             14387..14800
                     /gene="rplP"
                     /locus_tag="VLL59_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HER6509120.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            14810..15016
                     /locus_tag="VLL59_000991"
     CDS             14810..15016
                     /locus_tag="VLL59_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HER6509121.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            15042..15302
                     /gene="rpsQ"
                     /locus_tag="VLL59_000992"
     CDS             15042..15302
                     /gene="rpsQ"
                     /locus_tag="VLL59_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HER6509122.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            15327..15695
                     /gene="rplN"
                     /locus_tag="VLL59_000993"
     CDS             15327..15695
                     /gene="rplN"
                     /locus_tag="VLL59_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HER6509123.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            15774..16079
                     /gene="rplX"
                     /locus_tag="VLL59_000994"
     CDS             15774..16079
                     /gene="rplX"
                     /locus_tag="VLL59_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HER6509124.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            16103..16645
                     /gene="rplE"
                     /locus_tag="VLL59_000995"
     CDS             16103..16645
                     /gene="rplE"
                     /locus_tag="VLL59_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HER6509125.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            16661..16846
                     /locus_tag="VLL59_000996"
     CDS             16661..16846
                     /locus_tag="VLL59_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HER6509126.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            16997..17395
                     /gene="rpsH"
                     /locus_tag="VLL59_000997"
     CDS             16997..17395
                     /gene="rpsH"
                     /locus_tag="VLL59_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HER6509127.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            17598..18134
                     /gene="rplF"
                     /locus_tag="VLL59_000998"
     CDS             17598..18134
                     /gene="rplF"
                     /locus_tag="VLL59_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HER6509128.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            18239..18595
                     /gene="rplR"
                     /locus_tag="VLL59_000999"
     CDS             18239..18595
                     /gene="rplR"
                     /locus_tag="VLL59_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HER6509129.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            18614..19108
                     /gene="rpsE"
                     /locus_tag="VLL59_001000"
     CDS             18614..19108
                     /gene="rpsE"
                     /locus_tag="VLL59_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HER6509130.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            19123..19305
                     /gene="rpmD"
                     /locus_tag="VLL59_001001"
     CDS             19123..19305
                     /gene="rpmD"
                     /locus_tag="VLL59_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HER6509131.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            19521..19961
                     /gene="rplO"
                     /locus_tag="VLL59_001002"
     CDS             19521..19961
                     /gene="rplO"
                     /locus_tag="VLL59_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HER6509132.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            19978..21282
                     /gene="secY"
                     /locus_tag="VLL59_001003"
     CDS             19978..21282
                     /gene="secY"
                     /locus_tag="VLL59_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HER6509133.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            21432..22070
                     /locus_tag="VLL59_001004"
     CDS             21432..22070
                     /locus_tag="VLL59_001004"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HER6509134.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLDLVTDIEGNQEITDVFADVEKALLELK"
     gene            22188..22406
                     /gene="infA"
                     /locus_tag="VLL59_001005"
     CDS             22188..22406
                     /gene="infA"
                     /locus_tag="VLL59_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HER6509135.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            22432..22548
                     /gene="rpmJ"
                     /locus_tag="VLL59_001006"
     CDS             22432..22548
                     /gene="rpmJ"
                     /locus_tag="VLL59_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HER6509136.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            22566..22931
                     /gene="rpsM"
                     /locus_tag="VLL59_001007"
     CDS             22566..22931
                     /gene="rpsM"
                     /locus_tag="VLL59_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HER6509137.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            22949..23332
                     /gene="rpsK"
                     /locus_tag="VLL59_001008"
     CDS             22949..23332
                     /gene="rpsK"
                     /locus_tag="VLL59_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HER6509138.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            23378..24316
                     /locus_tag="VLL59_001009"
     CDS             23378..24316
                     /locus_tag="VLL59_001009"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HER6509139.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            24331..24717
                     /gene="rplQ"
                     /locus_tag="VLL59_001010"
     CDS             24331..24717
                     /gene="rplQ"
                     /locus_tag="VLL59_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HER6509140.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
BASE COUNT         7988 a         4434 c         5322 g         7416 t
ORIGIN      
        1 ctatctttta aagtagttca agagcttagt gctgttgact ggtggcgatt ataataaaag
       61 taggccactg ctctctttta ctttatgtta taatagtcct atggctagaa ttttagacaa
      121 taatgtaatg ggaaatgagg agttttcgga tcggactctt cgccctcaat atctacacga
      181 atatattgga caagataaag ttaaggaaca attcgctatt tttatagaag cagctaaaag
      241 acgtgacgaa tctttagacc atgttttatt atttggacct ccaggactgg gaaagacaac
      301 aatggcattt gtgattgcca atgaattggg agttaattta aagcaaactt caggtcctgc
      361 cgttgagaaa gctggagatt tggtagctat tttaaatgaa ttagaaccag gggatatttt
      421 gtttattgat gaaattcacc gcatgccaat gtctgtcgag gaagtactat atagtgctat
      481 ggaagacttc tatattgata ttatgattgg cgctggagat actagtcgta gtattcattt
      541 ggatctgcct ccatttacat tgattggtgc tactacacgt gcaggcatgt tatctaatcc
      601 cctcagagct cgttttggta tcactggtca catggaatac tatcaagaaa aggatttgac
      661 agagattgtg gagcgtacag ctactatttt tgaaataaaa atagaccatg aagctgcacg
      721 gaaattagct tgtcgcagta gaggaacgcc ccgcattgct aatcgattac taaaacgagt
      781 gcgtgactat gctcaaatta ttggtgatgg catcataacg gctcaaataa ctgatagagc
      841 tttgactatg ttagatgttg accgcgaagg tctcgattac attgatcaga aaattttacg
      901 aacgatgatt gagatgtatc agggagggcc agttggtttg gggacattat ctgtgaatat
      961 tgccgaggag cgtaatacag ttgaagagat gtatgaaccc tacttaattc aaaaaggctt
     1021 tctcatgcga acacgaacag gtcgtgtagc gacgcaaaag gcttatcgtc atcttggcta
     1081 tccctatcaa aacacttaat gatttttcaa atctaagaaa attaatctga acctgctttt
     1141 tgtgttcgga ttttttgata agttgacaga aaattattag attgatttct ccgatatcag
     1201 ttagaaattt gatataataa ttcaaaggag tatttaatga aaaaagtatg ttttgtctgt
     1261 ctgggtaata tttgtcgaag ccccatggct gagtttgtaa tgaagtcaat agtatcaagt
     1321 gatgttatga tgatagaaag tcgtgctatt tctgattggg agcatggaaa ccctattcac
     1381 tcaggtacac agtccatatt aaaaacttac caaattaatt atgatataac taaatgctcc
     1441 aagcagataa ctataactga ttttaacacc tttgactata ttattggtat ggatagcgat
     1501 aatgtgaaaa atctcaaaga gatgtcgcaa catcaatggg actctaaaat ctacctgttt
     1561 agagaagggg gtgttcctga tccttggtac actaacgatt ttgaagaaac ctaccaatta
     1621 gttagaaaag gatgccagga ttggctttct cgtttaatga gtaaagagta ttgatattag
     1681 aagttgagta aaagaaatga tagatatgca agatatagta aaaaaatgga gtattacacg
     1741 ggcgaagttg gaaattgtct cggtgattgt catattggtt tgtgcaattt ctgtttttag
     1801 cgtaagaatt tcgaataaga caagtttgac ctatgataaa gggcgtatgc actatactgg
     1861 ttacgtgatt aaccataaaa tgaatggaga agggaagctt gtctacccca acggtgatat
     1921 ctatgagggt acttttaaga atggcctatt tgaaggaaaa ggaactttta ctgctaagac
     1981 gggctggtta tataacgggg agtttcataa aggacaagca aatggcaaag gtgtgttaaa
     2041 agcaaagaat aataaagtct ataaagggat ttttaaacag gggatatttc aaaaatgaga
     2101 ataaaatggt tttcgtttgt tagggtaaca ggacttttac tggttttact ctaccacttt
     2161 tttaaaaatg tatttccagg aggttttatt ggtgttgaca ttttcttcac cttttcagga
     2221 tatctaatca cagccctctt gattgatgaa tacacaaaaa aagagtctat cgatattatc
     2281 ggttttttaa aaagacgctt ttatcgaatt gtccctcctt tggtgttaat gattttattg
     2341 accattcctt ttacgttttt aattaagaag gatttcattg ctaatatagg aagtcagatt
     2401 acagctgttt taggatttac cactaatatt tatgaaatat tgacgggaag tagttatgaa
     2461 agccaattta ttccacatct ctttgttcat acgtggagct tagctattga agttcatttt
     2521 tacttgtttt ggggtgtatt tgtttggtta ttagctagac gcaaggagac tcagaaacaa
     2581 ctgagaggac tactgttttt gatttctttg ggaatatttg ctattagttt cttgagcatg
     2641 tttataagat cttttatgac ctcaaatttt tccctgattt atttttcgag tctttctcac
     2701 agttttccct tctttttagg ggcgatgttt gccacgataa caggtattaa cgagactact
     2761 gttcgatttc aaaaaaatgt acgtttatgg ccgcgccagt atgtccttgc tgctatggtt
     2821 ggagcattta cacttttgct tgtgctaacg gtcacattgg attttaacca tatcacgacc
     2881 tatctatttg gctttgcttt ggctagctta ttcgcatcaa ttatgattta tgcagcgcgt
     2941 gttcttcatg agcaaacacc agatgtacaa gagcctaaag ctatcactta tatagctgat
     3001 attagctatg ggatttacct cttccattgg ccattttaca ttatttttag ccaattaatg
     3061 tctcatattt tggcagttat tctaacagtt ttcttttcaa tcttgtttgc cactgtgtct
     3121 tactatattg tggaaccttt gatccaaggg agaaaaccaa acctgcttgg tttagaaatt
     3181 gactgttctc cttactataa gtggattgta ggaggggctc tcgccttagc attattaact
     3241 ttaggaactt gtatgatagc gcctaaagtt ggtaagtttg agaaacaatt gttggttagt
     3301 tccctacaac aggctcaaag taatatggag cggacacata cactagctgc aggagacgct
     3361 aatgctttga gtgacgtagg tattattggt gattctgtag cattacgctc tagtgcggca
     3421 ttctcaaaaa ttatgccaca agcgcaactg gatgcagcgg tcagtcggaa ttttaaagaa
     3481 gctttcgatt tatttaataa ccaaattaaa tctaagagtc tatctaagac tgttgtctta
     3541 gcagtaggtg ttaactcgct tgacaactat tctcaagcag ttcagtcttt tattgaggca
     3601 ttgccaaaag gtcatcgttt agttttggtt tctccatata atgccaaaaa tgccagtcag
     3661 gttgcagaag ctagagacta tggtcttaaa ttgtccaaaa aatacaagta tgtcactatt
     3721 gcagactggt ataaagttgc tgttgaacat ccagatattt ggtatggcag tgacggtgtt
     3781 cattatagtg aagatagtca aggagcagaa ctatatgtct ccacaatcca gactgctgtt
     3841 gagaagtcag ctaaaaaacc agctaaataa agttaaaaaa tgtctaagag ataagtcaga
     3901 tctattgtgc tctggctttt tcttgtgaac aaatgatgat ggtaaaatag tagtactttg
     3961 aggtttttaa aagaaagcgg tttcagaaat aaaacggctt tttttagata tatttctgaa
     4021 aaaaagttaa tgaagaatat tgataccata ggatttcaga aataatttga aaaaaacttc
     4081 acaaatttat tgtgaaatga tttacaaaat ttcaaaaagt gctataataa ttttgtaaac
     4141 aaaattgtga aacttttaac aagataaagg agtctcaaat gactgaagga cataatactg
     4201 ttgaaacaac ctctgtttct gtgacaattg atgctcttgt tcaaaaaggt ttagctgctc
     4261 ttgaagagat gcgtaagctt gaccaagaac aagttgatta tatcgtagcc aaagcttctg
     4321 ttgctgcctt ggatgctcac ggtgaacttg ctaaacatgc ttatgaagaa acaggtcgcg
     4381 gtgtctttga agataaagca acaaaaaatc tatttgcttg tgagcatgtg gttaataaca
     4441 tgcgccatca aaaaacagta ggaattattg aagaagatga tgtgacaggt ttgacattaa
     4501 ttgctgagcc ggtgggtgtt atctgtggga ttacacccac aactaaccca acttcaacag
     4561 ctatctttaa atctttgatc tcgttaaaaa cacgtaatcc aattattttt gcctttcacc
     4621 catcagcaca agaatcatca gcacatgccg ctcgtattgt tcgtgatgct gctattgccg
     4681 ctggtgctcc tgaaaattgt gtgcagtggg ttgaaacacc atcacttgaa gcaacaaatg
     4741 ctttgatgaa tcatgacggc attgccacta tccttgcgac aggtggaaat gcgatggtta
     4801 aagcggcata ctcatgtggg aaacctgccc ttggggtagg tgctggtaac gttccagctt
     4861 atgttgaaaa atcagctaat atccgtcaag ccgctcatga tattgtgatg tctaaatcat
     4921 ttgataatgg tatggtctgt gcctctgaac aagctgttat catcgataaa gaaatctatg
     4981 acgattttgt agcagaattc aaatcttacc atacttattt tgtaaataaa aaagaaaaag
     5041 cccttcttga agaattctgt tttggtgcca aagcaaatag caaaaactgt gctggtgcaa
     5101 aattaaatcc aaatattgta ggaaaaccag ctacttggat tgcagaacaa gctggattta
     5161 ctgttccaga aggaaccaat attcttgctg cagaatgtaa agaagtttca gaaaatgagc
     5221 ctttaacacg tgaaaaatta tctccagtca ttgctgtttt gaaatctgaa tcacgtgaag
     5281 acggtgttga aaaagctcgt caaatggttg aatttaatgg actcggtcac tcagctgcca
     5341 ttcatacagc agatgcagag ttggcaaaag aatttggaac tagaatccgt gctatccgcg
     5401 tcatctggaa ttcaccttct acatttggtg gtatcgggga tgtttacaat gctttcttgc
     5461 catcattgac tcttggttgt ggttcgtatg gacgtaacgc agttggtgat aatgttagtg
     5521 ctataaatct cttgaacatc aaaaaagtag gaagacgtag aaataatatg caatggttta
     5581 aagttccttc aaaaacatac ttcgaacgtg attcaattca atatttgcaa aaatgtcgtg
     5641 acgttgaacg tgtcatgatt gttacagatc acgctatggt tgagcttggt ttcttggatc
     5701 gtatcattga acaacttgat cttcgtcgca ataaagttgt ttatcagatc tttgctgaag
     5761 tagaaccaga tccagacatt acaactgtta tgaaaggtac tgaattaatg cgtaccttca
     5821 aaccagacac cattattgcc cttggcgggg gatctcctat ggatgcagcc aaagttatgt
     5881 ggctcttcta cgagcaacca gaagttgatt tccatgacct cgttcaaaaa ttcatggata
     5941 tccgcaaacg tgcgttcaaa ttcccagaac ttggtaagaa aacaaaattt gttgctatcc
     6001 caacaacttc tggaacaggt tcagaggtga caccatttgc cgttatctct gacaaagcaa
     6061 ataatcgtaa atatccaatc gctgattact cattaacacc aactgtagcc attgttgacc
     6121 cagctttggt attgactgtt ccaggcttta ttgctgctga tactggtatg gacgttttga
     6181 cacacgcaac cgaagcttac gtgtcacaaa tggccaatga ctttacggat ggtttagctc
     6241 ttcaagccat taaaattgtt tttgataatc ttgaaaaatc agttaaaaca gccgattttg
     6301 aagcacgtga aaagatgcac aatgcgtcaa ctatggcagg tatggctttc gccaatgcat
     6361 tcttaggtat ttctcactca atggcgcata aaattggcgc acaattccat accgtacacg
     6421 gacgtacaaa tgcaattctt ttgccgtatg ttatccgcta taatggaact cgtccagcta
     6481 aaacggcgac atggcctaag tataattact accgtgcgga tgaaaaatac caagacattg
     6541 cgaaattgtt agggcttcca gcttctacac cagaagaagc agtggaatct tatgcgaaag
     6601 ctgtttatga tctgggttgc cgagttggta ttcaaatgaa cttcaaagct caaggtatcg
     6661 acgaaaatga atggaaagaa cattctcgtg aattggctta ccttgcttat gaagaccaat
     6721 gttcacctgc taacccacgt cttccaatgg ttgatcacat gcaagaaatt attgaagatg
     6781 cttactatgg ttatgctgaa cgtccaggac gacgtaagtg atttttaatg ttgataccag
     6841 gaaatgattt cttatgatta aagtcataag aaatcatttt attttctaaa tatatcattt
     6901 atatccagtg tcagaaaatg tagttaagta ttttgcagat aggcaaacag ctataagatt
     6961 aaccagttaa gtttcagaaa cttttcaggt ttctattgac tttcattgtg aaaagatgta
     7021 caatttatgt gtaaccgatt acaaaaaagt cattattaga tggaggactg atatgaaagc
     7081 cgtagttgtt aatcaagcta gtacaggtgt cgaagttgtt gagcatgatc ttccaaatat
     7141 tggtcatggt gaagcacttg ttaaagtaga atactgtggc gtttgtcata ctgatttaca
     7201 cgttgcacat ggcgattttg gtcaggtacc aggacgtatt ttggggcacg aaggtattgg
     7261 tatagtagaa gaaattggag aaggcgtaac atccttaaag gttggtgatc gtgtctctat
     7321 tgcatggttc tttgaaggat gtggtcattg cgaatactgt actacaggac gtgagacact
     7381 ttgtcgtagt gttaaaaatg ctggatacag tgttgatgga ggaatgagtg aatatgcagt
     7441 agtaacagct gaatatgcag ttaaagttcc agaaggttta gacccggctc aagcttcttc
     7501 cattacttgt gctggtgtaa caacttataa agctattaaa gaggcaggtg ctgctccagg
     7561 ccaatggatt gttatctttg gggctggtgg ccttggaaat ctggctgttc aatacgctaa
     7621 aaaagtcttt aatgcacatg ttgtcgcagt ggacattaat aatgataaac ttgagttagc
     7681 taaagaagtt ggcgcagata ttttagttaa cggcaaagaa attgaagatg ttccaggcta
     7741 tattcaagaa aaaaccggtg gagcacatgg tgttgtggta acggctgttt ctaaagttgc
     7801 ttttaaccaa gcaattgata gtgtccgtgc cggtggaaca gttgtagccg taggtctccc
     7861 atcagaatac atggaactgt ctatcgtaaa aactgtttta gatggtatca aagtggtcgg
     7921 atcacttgta gggacacgta aagacttgga agaagccttt gcctttggtg cagaaggtct
     7981 ggttgttccg gttgtcgaaa aagttccagt tgacactgct ccagaagtct ttgatgaaat
     8041 ggaacgtggt ttaatccaag ggcgcaaggt cttagatttc atcagctaaa catacaaatg
     8101 tattaaatat gagataagcc taagttgttt aaacttgatt ccaaataaaa tagcactctc
     8161 gagtatcaga aaacattttt gactcgagag tgctattttg atacattgaa agttgctaaa
     8221 tgaagaatat attatataat agaaaaaatt cgtttggagt ccttttgttc ttcgtcttct
     8281 tagttataaa cgttaggtaa atgttaagga ttggcatgtg gtcaattgtt gctgtagcac
     8341 taagtgtcgt gtatcttggg actctgctat taagatagac tttatgaatt cattaatgga
     8401 ccaaaataac tgaatgagtc cagtgactgt gtttgaaaaa atcgtttgat caagaatttt
     8461 ttattagggg acataaatga tatatagtag aagaaaaatt ttctctttag ctctgccttc
     8521 tatgatagaa aatattttac agatgttaat gggaatggtt gataattacc tggtggctca
     8581 aattggactt gtagcagtct ctggtgtctc catagctaac aacattatca gtatttatca
     8641 gtccctcttt atcgcgctgg gagctgctgt atctagtctg attgctcgaa gtattggaga
     8701 aaataatcag aacaaacaat taaactatat ggcaggtgtc ttgcaagtaa cactcctcct
     8761 ttcggtcggc ttagggttgt tatcagttgt tggacatcat caggtgttag aatggctagg
     8821 agctgaagct tctgtaacat tggttggagg gcaatatcta tccattgtcg gcggtatgat
     8881 tgttagtcta ggacttttaa ctagcttagg agctattgtt cgagctcaag ggtatcctaa
     8941 gattcctatg caagtgagct tattaataaa cgtactcaat gccatttttt ctgccttgtc
     9001 tatctatgta tggggatttg gtcttcttgg tgttgcttgg gcgacggttt tatctcgttt
     9061 agtgggtgtg tttttacttt gtcagtttat tcctattaaa caggttgcga aacgattgat
     9121 gagacctttg gacaaaatta tttttgattt atcactacct gctgctggtg aacgtttgat
     9181 gatgagagca ggagatgtcc taattattgg cattgttgtt cgctttggga caacggcctt
     9241 ggcaggtaat gctattggag aaaccttgac tcagtttaat tacatgcctg gcttagccat
     9301 ggcaacggca acaattattc tagtggccag gcaactgggg ggcggtaagg tgactgagat
     9361 aaggtatatt attagagaag cttttatttt atccaccctc atgatgctgg ttatgggagc
     9421 cttgacctat ctgctaggtc ctagtctctt gccgctattt actcagaata ctgatgctca
     9481 aaggtccgcc atggttgttt tactattttc tttactagga gctcccgcaa cggcaggcac
     9541 tttagtttat acagccgtct ggcagggttt gggaaaagca aagcttcctt tctatgcaac
     9601 aaccatagga atgtgggtga ttcgcattgg ccttggttat gtgattggtg tggtttggca
     9661 atatggactc ataggggtct ggatggcgac agtgttagat aataccagtc ggtggtttat
     9721 tctctctaaa caatttaaaa agtaccaaga aattaccttt cattaggaag gtagtttttt
     9781 tgaaaaaatg ccctaaaaag cttgcaatga ctaaatgatt ctgttattat attgtggtgc
     9841 tgtaaaaata cagctttagc aatgatacaa gaggttgcga cacgctcggt tgcattgcca
     9901 cgcaacaggt gtcggttttc ttgaggagct agcctattat cgtaaataga cgagaggaga
     9961 aaagatggca aacaaaaaaa tccgtatccg tttgaaagcg tacgaacacc gtacacttga
    10021 tacagcggca gaaaaaatcg ttgaaactgc aacacgtaca ggtgctacag ttgctggacc
    10081 agttccactt ccaactgaac gcagtcttta cacaattatt cgtgcgactc acaaatacaa
    10141 agattctcgc gaacaatttg aaatgcgtac acacaaacgt ttggtagaca tcatcaatcc
    10201 aacacaaaaa actgttgatg ctttgatgaa acttgatctt ccaagtggtg tcaacgtaga
    10261 aatcaaactt taatcggtga gattttgcaa gtacagttag tgtttgatgg aacttgaaca
    10321 cgagctaaac tctacatgaa aaagataaat cttcctcgaa acagaagttt ttgtgttaga
    10381 ttttctattt ttattttgag tttgacgctc tttgtatctt gctatgagca caaaaaacgc
    10441 tcgtaaaaaa cttttttgag cacaaaaaac gctcataaaa aactttttga aatattatta
    10501 agaaaaggaa atattttctc atgacaaaag gaatcttagg gaaaaaagtg ggaatgactc
    10561 aaatcttcac tgaatcaggc gaattcatcc ctgttactgt cattgaagca actccaaacg
    10621 ttgtgcttca agttaaaact gttgaaacag acggttatga agcagttcag gttggttttg
    10681 atgacaaacg tgaagtcttg agtaacaaac ctgccaaagg ccatgttgca aaagcaaaca
    10741 cagctcctaa gcgcttcatt cgcgaattca aaaacattga aggcttagaa gttggtgcag
    10801 aattatctgt agaacaattt gaagctggtg atgttgttga cgtcacaggg acatcaaaag
    10861 gtaaaggttt ccaaggtgtt atcaaacgcc atggtcaatc acgtggtcct atggctcacg
    10921 gttctcgtta ccatcgtcgc ccaggttcta tgggacctgt tgcgcctaac cgcgttttca
    10981 aaaacaaacg cttggcagga cgtatgggtg gtaaccgtgt aacagttcaa aaccttgaaa
    11041 ttgtacaagt tatcccagaa aagaacgtta tccttattaa aggtaacgta ccaggtgcta
    11101 agaaatctct tatcactatc aagtcagcag ttaaagctgc taaataataa gaaaggagaa
    11161 aacagttaaa atggcaaacg taaaactatt tgaccaaact ggtaaagaag ttagctcagt
    11221 tgaattaaac gacgctatct tcggtatcga accaaacgaa tcagttgttt ttgatgttgt
    11281 aattagccaa cgcgctagcc ttcgccaagg tactcatgcg gttaaaaacc gttcagcagt
    11341 atcaggtggt ggacgtaaac catggcgtca aaaaggaact ggacgcgctc gtcaaggttc
    11401 tatccgctca ccacaatggc gtggtggtgg tgttgtcttt ggaccaactc cccgttcata
    11461 cggatacaaa cttccacaaa aagttcgtcg ccttgcgttg aaatcagttt actcagcaaa
    11521 agttgctgaa gataaatttg tagctgtaga aggcctttca tttgcagcac caaaaactgc
    11581 tgaatttgca aaagtgcttt cagctcttag cattgataca aaagtacttg ttcttgttga
    11641 agaaggaaat gaatttgcag cactttctgc acgtaacctt ccaaacgtaa ctgttgcaac
    11701 tgcagcaact gcaagtgttc ttgatatcgt gaacgcagac aaacttcttg ttactaaaga
    11761 agcaatctct acaattgagg aggttcttgc ataatgaatt tgtacgacgt aatcaaaaaa
    11821 ccagttatca ctgagaagtc aatgattgct cttgaagcag gcaaatacac tttcgaagtt
    11881 gatactcgtg cacacaaact tttgatcaaa caagctgttg aagctgcttt tgacggagtt
    11941 aaagttgcaa gtgtaaacac tgttaacgtt aaaccaaaag caaaacgcgt tggtcgttac
    12001 acaggtttca cttcaaaaac taaaaaagct atcatcactc ttacagctga ttctaaagca
    12061 atcgagttgt tcgcagctga agctgaataa tctaaggagg aaataacgtg ggtattaaag
    12121 tttataaacc aacgacaaat ggccgtcgta acatgacttc tttggatttc gcggaaatca
    12181 caacaagcac gcctgagaaa tcattgcttg tttctcttaa gagcaaagct ggtcgtaaca
    12241 acaatggtcg catcacagtt cgtcaccaag gtggtggaca caaacgtcat taccgtttga
    12301 tcgacttcaa acgtaacaaa gatggcgttg aagcagttgt taaaacaatc gaatatgatc
    12361 caaaccgtac tgcaaacatc gcacttgtac attacactga cggtgtgaaa gcttacatca
    12421 ttgcacctaa aggtcttgaa gtaggtcaac gtattgtttc tggtccagat gcagatatca
    12481 aagttggtaa cgcacttcca ttagcaaaca ttcctgtcgg tacagttgtt cacaatattg
    12541 agttgaaacc tggtaaaggt ggagaacttg ttcgtgcagc tggagcttct gctcaagtac
    12601 ttggtcaaga aggtaaatac gttcttgttc gtcttcaatc aggcgaagtt cgtatgattc
    12661 ttggtacatg ccgtgcaact atcggtactg ttggtaacga acaacaatca cttgttaaca
    12721 ttggtaaggc aggacgtagc cgttggaaag gtatccgccc aacagttcgt ggttctgtaa
    12781 tgaaccctaa cgatcaccca cacggtggtg gtgaaggtaa agcaccagtt ggacgtaaag
    12841 cgccatcaac tccatggggt aaaccagcgc ttggtcttaa aactcgtaac aagaaagcta
    12901 aatcagacaa acttatcgtt cgtcgtcgta acgaaaaata attttagtaa gttgcttaaa
    12961 acttgctgaa atagcgttac aatagctttg ctatttattc cgccaactcg gtagagtttg
    13021 gagtcttgct ctgaactcaa gccgctgtgg tacattattt aaaggagaaa actacaaaat
    13081 gggacgtagt cttaaaaaag gacctttcgt cgatgagcat ttgatgaaaa aagttgaagc
    13141 tcaagcaaac gacgaaaaga aaaaagtaat caaaacttgg tcacgtcgtt caacgatttt
    13201 cccaagtttc atcggatata caattgcagt ttatgacgga cgtaaacatg tacctgttta
    13261 catccaagaa gacatggtag gtcacaaact tggtgaattt gcaccaacgc gtacttacaa
    13321 aggtcacgca gctgacgaca agaaaacacg tcgttaatag gaggaggaca caatggcaga
    13381 aattacttca gctaaagcaa tggctcgtac agtgcgtgtt tcacctcgta aaacacgttt
    13441 agtacttgat cttatccgtg gtaagaaagt tgctgacgca atcgcaatct taaaattcac
    13501 tccaaacaaa gcagctcgtg ttattgagaa aactcttaac tcagcaattg ctaacgcaga
    13561 aaacaacttt ggtttggaaa aagcaaactt ggtagtatct gaaacattcg ctaacgaagg
    13621 accaacaatg aaacgtttcc gtccacgtgc gaaaggttca gcttcaccaa tcaacaaacg
    13681 tacaactcac gtaactgtag ttgtatcaga aaaataagga ggtaaaatcg tgggtcaaaa
    13741 agtacatcca attggtatgc gtgtcggaat catccgtgac tgggatgcga aatggtatgc
    13801 tgaaaaagaa tacgcggatt accttcatga agatcttgca atccgtaaat tcattaataa
    13861 agaattagct gacgcatcag tttcaactat tgaaattgaa cgtgcagtaa acaaagttat
    13921 tgtttcactt cacactgcta aaccaggtat ggttatcggt aaaggtggcg caaacgttga
    13981 cgctcttcgt ggtcaactta acaaattaac tggaaaacaa gtacacatca acatcatcga
    14041 aatcaaacaa cctgatttag atgctcacct tgttggtgaa aacattgctc gtcaacttga
    14101 gcaacgtgtt gctttccgtc gtgctcaaaa acaagcaatc caacgtacaa tgcgtgcagg
    14161 agctaaaggg attaaaactc aagtttctgg tcgtttgaac ggtgctgata tcgctcgtgc
    14221 tgaaggttat tcagaaggaa ctgttccact tcacacgctt cgcgctgata tcgactatgc
    14281 ttgggaagaa gctgacacaa cttatggtaa acttggcgtt aaagtttgga tttaccgtgg
    14341 agaagttctt ccagctcgta aaaacactaa aggaggcaaa taacaaatgt tagtacctaa
    14401 acgtgttaaa caccgtcgcg aattccgtgg aaaaatgcgc ggtgaggcta aaggtggtaa
    14461 agaagtttca ttcggtgaat acggacttca agccacaact agccactgga ttacaaaccg
    14521 tcaaatcgaa gctgcccgta ttgcgatgac tcgttacatg aaacgtggtg gtaaagtttg
    14581 gattaaaatc ttcccacaca aatcatacac tgcaaaagct atcggtgtac gtatgggttc
    14641 tggtaaaggg gcacctgaag gttgggtagc accagttaaa cgtggtaaag tgatgtttga
    14701 aattgctggt gtttctgaag aaattgctcg cgaagcatta cgtcttgcta gccacaaatt
    14761 accagttaag tgcaaattcg taaaacgtga agcagaataa ggagaagaca tgaaacttca
    14821 agaaattaaa gattttgtta aagagcttcg tggattgtct caagaagaac ttgctaagaa
    14881 agaaaacgag ctcaaaaaag aattgtttga tcttcgtttc caagctgcag caggtcaact
    14941 tgaaaagact gctcgccttg acgaagttaa gaaacaaatt gcacgtgtta aaactgtgca
    15001 atcagaaatg aaataataga ttgggaaagg agaaattcta aatggaacgt aatcaacgta
    15061 aaactcttta cggacgcgta gtgtctgaca agatggacaa aacaatcaca gttgtagttg
    15121 aaactaaacg taaccaccca gtctatggta aacgtatcaa ctattctaaa aaatataaag
    15181 cacatgacga aaacaacgtt gctaaagaag gcgatatcgt tcgtatcatg gaaactcgcc
    15241 cactttcagc tacaaaacgt ttccgtcttg tggaagtagt ggaaaaagct gttattatct
    15301 aatcaaacta aaaggagaaa attgaaatga ttcaacaaga aactcgcttg aaagttgctg
    15361 ataatagcgg tgctcgtgag atcttgacta tcaaagtact tggtggttca ggacgtaaat
    15421 tcgctaacat cggtgacgta atcgttgctt ctgtaaaaca agctactcct ggtggagcag
    15481 ttaaaaaagg tgatgtggtt aaagctgtta tcgttcgtac aaaaactggt gcacgccgtc
    15541 cagacggttc atacatcaaa tttgacgaca atgctgctgt aatcatccgt gatgataaaa
    15601 ctcctcgcgg aactcgtatc tttggcccag ttgcacgcga attgcgtgag ggtggctaca
    15661 tgaagatcgt atcacttgca ccagaagtac tttaatctca ggttaacaaa cgtagtcccc
    15721 taggttttcc tagggtgccc atcggggcgt aagaaataat aggagaaacc agaatgtttg
    15781 taaaaaaagg cgacaaagtt cgcgtaattg ctggcaagga caaaggcact gaagctgtag
    15841 ttcttaaagc acttccaaaa gttaacaaag ttattgttga aggtgttgga atgattaaaa
    15901 aacaccaaaa acctaacact gaaaatcctc aaggagctat cgtcgaaaaa gaagcaccta
    15961 tccatgtctc taatgttcaa gtattagata aaaatggtgt agctggacgt gttggttata
    16021 aagttgttga cggtaaaaaa gtacgttaca gcaaaaaatc aggcgaagtg cttgattaat
    16081 cacgaaggaa aggagaagca taatggcaaa tcgtttaaaa gaaaaatata ctaacgaagt
    16141 aattcctgcg ttgacagaga aattcaatta cacatcagtt atggctgtgc caaaagttga
    16201 gaaaattgtt ctcaatatgg gtgttggtga tgctgtatcc aacgcaaaaa acctagagaa
    16261 agctgcagct gaattagcgc ttatctcagg tcaaaaacca cttattacta aagctaagaa
    16321 atcaatcgct ggcttccgtc ttcgtgaagg tgtagcgatc ggtgcaaaag ttaccctccg
    16381 tggcgaacgt atgtacgaat tcctagacaa attggttagc gtttcacttc ctcgtgtacg
    16441 tgacttccat ggcgttccaa caaaatcgtt tgatggacgc ggaaactaca ctctcggtgt
    16501 gaaagaacaa cttatcttcc cagaaatcag ctttgatgat gttgataaag tacgtggtct
    16561 tgatattgta atcgtcacta ctgcaaatac tgacgaagaa tcacgtgaat tgcttaaggg
    16621 ccttggaatg ccttttgcaa aataataggg ggtaaataaa ttggctaaaa aatctatgat
    16681 tgctaagaac aaacgtcctg caaaacactc tacacaagct tatactcgct gtgaaaaatg
    16741 tggacgtcca cattcagttt accgcaagtt taaactttgt cgtgtttgct tccgtgaatt
    16801 ggcttacaaa ggtcaaattc caggtgttgt caaagcttct tggtaaaaat atgacacaaa
    16861 acttaatttg ttcttcagat taagtcttgt gcttaattaa aacggtgtga gcataagctg
    16921 ataccaaagt cctttaagga caacattaac tagtaagtga tagcatcaaa ctgctagtaa
    16981 gaggagaata taaaaaatgg ttatgactga cccaattgca gactttttaa cacgtatccg
    17041 taatgctaat caagtaaaac acgaagtgtt agaagtacct gcttcaaaca ttaaaaaagg
    17101 gattgctgag attcttaaac gtgaaggttt tgtaaaaaat gttgaagtta tcgaagatga
    17161 taaacaaggc atcattcgtg tgttcttaaa atacggaaaa aatggtgagc gtgttatcac
    17221 taacttaaaa cgtatttcaa aaccaggtct tcgcgtttac gcaaaacgtg atgacatgcc
    17281 taaagttctt aacggacttg gaattgcaat catttcaaca tcagaaggtc ttttgactga
    17341 caaagaagct cgccaaaaga atgttggtgg agaagtgatc gcttacgttt ggtaatttaa
    17401 gatactaaga gcgtcgtgga caaagtgaaa ataggaaatc tgacgtagcg tgtttacact
    17461 caaggaagat ttatcttttt cacacagacc acagctcgtg ttcaattttg aaatataaat
    17521 tgaagtatat cattctatca accccccgtg aaaactagtc gctatgcggc ttgacaattt
    17581 aacaggagaa aataaacatg tcacgtattg gtaataaagt aattactatg cctgcaggcg
    17641 ttgaattaac aaataacaac aatgttatta ctgttaaagg ccctaaaggc gaactcactc
    17701 gtgagtttaa caaaaatatt gaaatcaaag ttgaagggac tgaaatcaca gttgtacgtc
    17761 ctaacgactc aaaagaaatg aaaacaatcc atggtacaac ccgtgctaac ttgaataaca
    17821 tggttgtagg tgtttctgaa ggtttcaaaa aagatcttga aatgaagggt gtcggttacc
    17881 gtgctcaact tcaaggtact aaacttgtcc tttcagtagg taaatctcac caagacgaag
    17941 ttgaagctcc agaaggaatt actttcactg ttgctaaccc aacttcaatc tcagttgaag
    18001 gaatcaacaa agaagttgtt ggtcaaacag ctgcttacat ccgtagcttg cgttcaccag
    18061 agccttacaa aggcaaaggg atccgttacg ttggtgaata cgtacgcctt aaagaaggta
    18121 aaacaggtaa ataatgttct tagtcgggta tgggaagtat tgcaccttaa catgctcgat
    18181 aagttcaatc gacaacttgt caatgagaca aattgattaa aattaagagg tgaaaattgt
    18241 gatttcgaaa ccagataaaa acaaaatccg ccaaaaacgc caccgtcgcg tccgcggtaa
    18301 actctctgga actgctgatc gcccacgttt gaacgtattc cgttctaata caggcatcta
    18361 cgctcaagtt attgatgacg tagcgggtgt aacgctcgca agtgcatcaa ctcttgataa
    18421 agacgtttct aaaggaacaa aaacagaaca agccgttgta gtcggcaaac ttgttgctga
    18481 acgtgcagtg gctaaaggta tttctgaagt ggtgtttgac cgcggtggat atctctatca
    18541 cggacgtgtt aaagccttgg ctgatgcagc tcgtgaaaac ggattgaaat tctaataggg
    18601 aggacacaaa ataatggcat ttaaagataa tgcagttgaa cttgaagaac gcgttgttgc
    18661 gattaaccgc gttacaaaag ttgttaaagg tggacgtcgt cttcgctttg cagctcttgt
    18721 agttgttggt gatggaaatg gtcgtgttgg atttggtact ggtaaagctc aagaagttcc
    18781 agaagctatc cgtaaagcag ttgaagctgc taagaaaaac atgatcgaag taccaatggt
    18841 tggtacaaca atccctcacg aagtttacac taacttcggt ggagctaaag tattattgaa
    18901 accagctgta gaaggttctg gagttgctgc tggtggtgca gttcgtgccg tcatcgaatt
    18961 agcaggtgtt gctgatatta cttcaaaatc tcttggttca aacactccaa tcaacattgt
    19021 tcgtgcaact gttgaaggat tgaaacaact taaacgtgca gaagaagttg ccgcacttcg
    19081 tggcatctca gtttctgact tagcataaga aaggggatca tcatggctca aattaaaatt
    19141 actttgacta agtctcctat cggacgtaag ccagaacaac gtaaaactgt tgttgctctt
    19201 ggacttggta aattaaactc ttcagtagtc aaagaagata atgctgctat ccgtggtatg
    19261 gtgacagcta tttctcactt ggttaccgtt gaagatgtta aataagttat aactgtgaaa
    19321 tctctggttt cataattaaa aacgagcaca aaaccgactc ttgtagtttg cttttttggc
    19381 aacaaacagt agtcggttag tgcgtatctg tattaagtta ttttggataa cttaagtatc
    19441 attaatgtat aggcgagttt ctatagggag tccttttccc tcatagaggc gctagcattt
    19501 tacaaaaaaa aggagaaaaa atgaaacttc atgaattaaa agctgctgaa ggctcacgta
    19561 aagtacgtaa ccgtgttggt cgtgggacat catcaggtaa tggtaaaaca tctggtcgcg
    19621 gtcaaaaagg tcaaaaagct cgtagcggtg gcggtgtacg tttaggtttt gaaggtggac
    19681 aaacaccatt gttccgtcgt attccaaaac gtggctttac aaatattaat actaaagaat
    19741 atgcacttgt gaatcttgat caactgaatg tttttgatga tggtacagaa gtgactccgg
    19801 ctattttaaa agatgctggt attgtccgag ctgaaaaatc aggtgttaaa gtgcttggta
    19861 acggtgaatt gactaaaaaa ttgactgtaa aagcagctaa gttctcaaaa tctgctgaag
    19921 cagctattat tgctaaaggt ggttcaatcg aagtcatcta atgaggggat actcattatg
    19981 ttcttaaaaa tactaaaaga cgcgttaaag ataaagactg tacggaataa aattttcttt
    20041 actatattta tcattcttgt attccgaatt gggacacata ttaccgtacc tggtgtaaat
    20101 gccaagagct tagagcaatt aagtgaactc cctttcttaa atatgttaaa cttagttagt
    20161 ggtaatgcga tgagaaattt ctcagtattt tcaatggggg ttagcccata tattactgct
    20221 tctatcgttg ttcagttatt gcagatggat attttaccta agtttgttga gtggggcaaa
    20281 caaggtgagg ttggacgtcg taaattaaat caagcgacgc gctatatttc acttgttttg
    20341 gcttttgccc aatccattgg tatcactgca gggtttaata ctttgtcgaa cgttgcactt
    20401 gttaagacac cagacatcaa aacatattta ctgatcgggg cattactgac aacaggtagc
    20461 gttattgtta cctggcttgg agaacaaatc acagataaag gatttggtaa tggcgtatca
    20521 atgattatct ttgcgggtat tatttcgtct attccaagtg caattgcaac aattcgtgaa
    20581 gactattttg taaatgttaa ggcaagtgat ttacactcgt cttatctcat tgttgggatt
    20641 ttaatcatag ctgttcttgc tattgttttc tttacaacat atgtccaaca agcggaatat
    20701 aaaattccaa tccaatacac aaagctaatg caaggtgcac ctacaagttc atatcttcca
    20761 ttaaaagtaa atccagccgg cgttattccc gttatctttg ctagctcgat tacaactatc
    20821 ccaagtacga ttattccttt tgttcaaaat ggtagagatt taccgtggtt aaaccgtttg
    20881 caagaaattt ttaattatca aactccagtc ggaatgatag tttacgcctt gttgattata
    20941 ttgttctcat tcttctatac ctttgtacaa gttaatcctg agaagacagc agaaaatctt
    21001 cagaagaatt cctcatatat accaagtgtt cgccctggac gtgagacaga acaatttatg
    21061 tccgcattgc taaaaaaact agcaaccgta ggagctatct tcttagcatt tatctcttta
    21121 gcgccaatag cagcacaaca agctctcaac ctttcttcta gtattgcttt aggtggaact
    21181 agtttgctca ttttgatttc aactggtatc gaaggtatga aacagcttga ggggtatctt
    21241 ctaaagagaa aatatgtcgg atttatgaat acagcagaat agaatacagg ttgacattgt
    21301 caaccttcta ttttgttttt aaatgacaat aagacttggt tatcatcaaa cgatttcttg
    21361 ttgccatttg aaaacaaaaa ccaaggaaaa taatttccta ctatgtattt attttaaaag
    21421 aggaggaaaa gatgaatctt ttaatcatgg gtttgccggg agctggtaaa gggacccaag
    21481 cagctaagat tgttgaagaa tttggtgttg ctcacatctc aacaggggat atgttccgcg
    21541 ccgcaatggc taatcaaacc gaaatgggac gtttagctaa aagttatatt gataaaggtg
    21601 aattggttcc tgatgaagtc acaaacggga ttgtaaaaga gcgcttagct gaggatgata
    21661 tcgcagaaaa aggttttttg cttgatgggt atccacgtac tattgaacaa gcacacgcct
    21721 tagatgcaac acttgaagaa ctaggactcc gcttagatgg tgttattaat attaaagtgg
    21781 atccatcatg tcttgtagag cgtttgagtg gtcgtattat caatcgtaaa actggtgaaa
    21841 cgttccataa agtgttcaac ccaccagtag attataaaga agaagattac tatcaacgtg
    21901 aagatgataa gcctgaaact gttaaacgtc gtttggacgt caatatggct caaggagaac
    21961 ctattcttga acactatcgt aagcttgatc ttgttacaga tattgaaggt aatcaagaaa
    22021 taacagacgt ttttgcagat gttgaaaaag cgttgctaga actcaaataa attatactaa
    22081 tctacttgca taagtagatt agtaatgata tactagttta gtctgactta taattgttac
    22141 ctctgtgctc agaggacatc aaatcgaaat ttagggggta cttttgcgtg gcaaaagaag
    22201 acgtgattga aattgaaggc aaagtagtag aaacgatgcc aaatgcaatg tttactgttg
    22261 aattggaaaa tggacatcaa attctagcaa ctgtatcagg aaaaatccgc aaaaattaca
    22321 ttcgtatttt agtaggtgac cgtgttacag tagaaatgag tccttatgac ttgacacgtg
    22381 gacgcatcac ataccgcttt aaataatcga aataattgga gggattaaaa catgaaggta
    22441 agaccatcgg ttaaaccaat ttgcgaatac tgtaaagtta ttcgccgtaa tggtcgtgtt
    22501 atggtaattt gtccgacaaa tccaaaacac aaacaacgtc aaggataaaa tagaaaggag
    22561 aaaaaatggc tcgtattgct ggagttgata ttccaaatga taaacgcgta gtaatttcac
    22621 ttacttatgt ttacggaatt ggtcttgcaa catctaaaaa aatcttagca gctgcaggta
    22681 tttctgaaga tatccgtgtt aaagatttaa catcagatca agaagatgct atccgtcgtg
    22741 aagtggatgc aatcaaagtt gaaggtgacc ttcgacgtga agtaaacatg aacattaaac
    22801 gtttgatgga aatcggttca taccgtggaa tccgtcatcg tcgtggactt cctgtccgtg
    22861 gacaaaatac taaaaacaat gctcgcactc gtaaagggaa agctgttgcg attgcaggta
    22921 agaaaaaata aaataggagg taaaacaatt ggctaaacca acacgtaaac gtcgtgtgaa
    22981 aaagaacatc gaatctggtg ttgcacacat tcacgctaca tttaataaca ctattgttat
    23041 gattacagat gtgcatggta atgctcttgc atggtcatca gctggtgctc ttggtttcaa
    23101 aggttctcgt aaatctactc catttgctgc tcaaatggct gcagaagctg ctgcaaaatc
    23161 tgcacaagaa cacggactaa aaactgttga agtgactgta aaaggtcctg gttcaggtcg
    23221 tgaatcagct attcgtgctc tagcagctgc aggtcttgaa gtaactgcaa ttcgtgatgt
    23281 gacccctgtg ccacataatg gtgctcgtcc tccaaaacgt cgtcgtgtat aatcatataa
    23341 caaatagtac acaagtttcg tttcgagggg tgaaaaaatg attgagtttg aaaaaccaat
    23401 aataacaaaa attgatgaaa ataaagatta cggtagattt gtcatcgaac cacttgaacg
    23461 tggctacgga acaactctag gtaattctct tcgtcgtgta ctcttgtctt cacttccagg
    23521 tgcagcagta acatcaatta aaattgatgg agtactacac gaatttgata caatcccagg
    23581 tgtacgtgaa gatgtcatgc aaattatcct taatgttaag ggacttgctg tgaaatcata
    23641 cgtcgaagac gaaaagatta tcgaacttga agtagaagga ccagcagagg taacagctgg
    23701 tgatattctt actgacagtg atatcgaact tgttaacccg gatcattatc tttttacaat
    23761 cgctgaagga cattctctac gtgcaacaat gactgttgct aaaaaacgtg gttatgtgcc
    23821 agcagaaggc aacaaaaaag atgatgcacc tgtgggtaca ttggcagtag attcaatcta
    23881 tacgccagtt aaaaaagtta attatcaagt tgaacctgcc cgtgtaggta gcaatgatgg
    23941 ctttgataaa ttaacgattg aaatcatgac aaacggaaca attattcctg aagatgcttt
    24001 aggtctatct gctcgagttt tgatcgaaca cttaaacctg tttactgatt taacagaggt
    24061 tgcaaaagct accgaagtaa tgaaagaaac tgaaaaagtg aacgatgaaa aggtacttga
    24121 ccgcaccatc gaggagcttg atttatccgt acgctcatat aactgtttaa aacgtgcagg
    24181 cattaacact gtcttcgact taacagaaaa atctgagcct gaaatgatga aagtccgtaa
    24241 tctgggacgt aagagccttg aagaagttaa ggttaaactt gctgacttag gtctcggact
    24301 aaaaaacgat aaataatata ggaggacaaa atggcttacc gtaaactagg acgcactagc
    24361 tcacaacgta aagcaatgct tcgtgatttg acgacagatc ttttgatcaa cgaatcaatt
    24421 gtaacgacag aagcacgtgc aaaagaaatc cgtaaaacag ttgaaaaaat gattactctt
    24481 ggtaaacgtg gtgatcttca tgctcgtcgc caagcagctg catacgttcg taacgaaatc
    24541 gcatcagaaa attatgatga agctaccgat aaatacacat caacgacagc tcttcaaaaa
    24601 cttttctcag aaattgcacc tcgttatgca gaacgtaacg gtggatacac tcgtattctt
    24661 aaaacagaac cacgccgtgg agatgctgct ccaatggcaa ttattgaatt agtttaattt
    24721 ttatcaattt tgttgagtgt tatgatgatg gagtaatcga gagattattc ttagtctagc
    24781 tctggtctac cgctaggatt tttcctagcg ggaacactca tcatattgtt aatatgtaac
    24841 gcttgtttat gaaaggtatc taagctatag aaacttttta taagcaggcg ttttgttgta
    24901 ttatgaggtg acactcccgc ttttaagctg agtaaaacaa taacacagaa gcctcttctg
    24961 atgcgtttat aaagttttct cagagacaat aaggtcatta gaataagaaa accttataca
    25021 ggtgtttaaa gacctctcat gggcaaataa acggtgtaat cctctcattt aaatgttcga
    25081 aaaaatactt gcatcgcaaa cagatgctca aactatattg ttagttttat cccctattca
    25141 atattttatt aataagtatt
//
LOCUS       DAUNLR010000024        21765 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUNLR010000024 DAUNLR010000000
VERSION     DAUNLR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21765
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.024"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(411..578)
                     /locus_tag="VLL59_001011"
     CDS             complement(411..578)
                     /locus_tag="VLL59_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509141.1"
                     /translation="MKKKLSLFMIATAAVAGLSLATLGSHQTVSANDASYSNGFYGHT
                     GPDSWLLYTVW"
     gene            complement(770..1039)
                     /locus_tag="VLL59_001012"
     CDS             complement(770..1039)
                     /locus_tag="VLL59_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509142.1"
                     /translation="MKNKLFLVALATVTVLGPSLATPHHQTVHATEYCTYASDNPHVG
                     LCHEKEDGIQTEEKTFKTVTNSDSSFFTWLWTKIKTWFSSLMGIN"
     gene            1523..2661
                     /locus_tag="VLL59_001013"
                     /pseudo
     CDS             1523..2661
                     /locus_tag="VLL59_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
     gene            2872..5373
                     /locus_tag="VLL59_001014"
     CDS             2872..5373
                     /locus_tag="VLL59_001014"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HER6509143.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGDELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            5680..7113
                     /locus_tag="VLL59_001015"
     CDS             5680..7113
                     /locus_tag="VLL59_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HER6509144.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            7184..7462
                     /locus_tag="VLL59_001016"
     CDS             7184..7462
                     /locus_tag="VLL59_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HER6509145.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            7585..8070
                     /locus_tag="VLL59_001017"
     CDS             7585..8070
                     /locus_tag="VLL59_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HER6509146.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQGAVRLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKDSPYLEGMDLN
                     A"
     gene            8161..8823
                     /locus_tag="VLL59_001018"
     CDS             8161..8823
                     /locus_tag="VLL59_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HER6509147.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADIKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     IKEVRGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            8828..9691
                     /locus_tag="VLL59_001019"
     CDS             8828..9691
                     /locus_tag="VLL59_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HER6509148.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDSATEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVILSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETRAAIKEAQDF
                     LYPLIEKAGLT"
     gene            9693..10397
                     /locus_tag="VLL59_001020"
     CDS             9693..10397
                     /locus_tag="VLL59_001020"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HER6509149.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNSSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVILEEVAKMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            10722..12368
                     /locus_tag="VLL59_001021"
     CDS             10722..12368
                     /locus_tag="VLL59_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HER6509150.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            12621..13712
                     /gene="ulaG"
                     /locus_tag="VLL59_001022"
     CDS             12621..13712
                     /gene="ulaG"
                     /locus_tag="VLL59_001022"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HER6509151.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            14199..15395
                     /locus_tag="VLL59_001023"
     CDS             14199..15395
                     /locus_tag="VLL59_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HER6509152.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            15411..17138
                     /locus_tag="VLL59_001024"
     CDS             15411..17138
                     /locus_tag="VLL59_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HER6509153.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMAMTSGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAQKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     QSKVSSWTK"
     gene            17269..19911
                     /gene="polA"
                     /locus_tag="VLL59_001025"
     CDS             17269..19911
                     /gene="polA"
                     /locus_tag="VLL59_001025"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HER6509154.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVVS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSYLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            20099..20554
                     /locus_tag="VLL59_001026"
     CDS             20099..20554
                     /locus_tag="VLL59_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HER6509155.1"
                     /translation="MIYSFQNPSEDVLKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEAQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNH"
     gene            20606..21073
                     /gene="perR"
                     /locus_tag="VLL59_001027"
     CDS             20606..21073
                     /gene="perR"
                     /locus_tag="VLL59_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HER6509156.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQPDF"
     gene            21229..21528
                     /locus_tag="VLL59_001028"
     CDS             21229..21528
                     /locus_tag="VLL59_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509157.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     VNFDDLRLTMVDMVSLSSEYDVIVTDMILEQTTDSEILFFNQMAPSVVANRLTDM"
BASE COUNT         6400 a         4129 c         4766 g         6470 t
ORIGIN      
        1 tgtaactcct taaattatag tatacctata ttatactcat attctattaa tgattcaaca
       61 tcacatttta atctttttgt gatgtgtctg accgaaaaag gcaaagaaag ctaatattaa
      121 agtatttctt tatcttatac aaataacatt aatggctaat aatattaatc tggttatcat
      181 tctatttgag atgttacagc ttttttggtg ctggttagct agcaactgtt acgacttgtg
      241 ttttgggctc ctctcctttt ataggcagtg taccttttct gttttacctt gaggtgtcat
      301 tggcaaaaac gttttagcca atcaaaaagc ctaaggctgc ttatgcagcc ttaggctttt
      361 cataaccgta gtcttacgaa gaagatagct tctatattac ggtatgaggt ttaccataca
      421 gtgtaaagta accagctgtc aggaccagtg tgtccgtaga aaccgttact atagctagca
      481 tcatttgctg aaacagtttg gtggcttcct agtgttgcaa ggctaaggcc tgcaacagca
      541 gcagttgcga tcataaataa agataatttc tttttcatag ataactcctt taatttgtag
      601 tatgactata ttatactaat tttttgttca taaatcaagt attattttaa tgtttttgtt
      661 attatttatc tgaataagaa atgtggcgac ctaggattag aaaaccgcca cgagatggtt
      721 ttttataatt ggctgtggga actgtttaac ttttacaagt gagtttgttt tagtttattc
      781 ccattaatga agaaaaccaa gttttgattt ttgtccaaag ccatgtaaaa aatgaggaat
      841 cactatttgt tacagtttta aaagtttttt cctctgtttg aatgccgtct tctttttcat
      901 ggcaaagacc tacatgtggg ttatctgatg cataggtaca atactcagtt gcatgcacgg
      961 tctggtgatg aggggttgct aaagacggcc ctaggacggt tacggtcgcg agggcaacta
     1021 aaaataattt gtttttcact atatttctct cctaaaaata aatagtactt tagcagtgta
     1081 ctataagacg catggtgaaa acaagttctg tttctcatta aatgaaataa attgtgacct
     1141 tttaatgaaa ttttgatggc aatattgccc tattgagtag gtgacgatgc aaagtaggac
     1201 tgtcagtgtg ataagctgag cttttgagac gatgaggcca aaggtagcta tactttaact
     1261 tgctggagag gtgttggcag cttggtcaaa gatgataaaa gggcttgcaa acttagctaa
     1321 aggttgtata ataaacgtaa tcgatctaaa aatgatatta ttggaaaaat tcattgtcca
     1381 tttaaaaggt gcccactact tttcttatag gttagcagat cacgcttttt tgaagagctt
     1441 tttggcttgt gcaaccattg gggtgggacc attgtctaaa agagagttca ttggagtcaa
     1501 cgctattgcg gaggtgcacg aaatgaaaga aaacactact ttattacatg gctatacggt
     1561 tattgacgag tttacaggag cagcttcagt tcccatctat cagacttcga cgttccacaa
     1621 ttcagaactg tattgtccta gtcaaaaaca tttgtacaca cgcttttcaa acccaacgac
     1681 tgaagcttta gaagacgggt tagcctgttt agaaaaagcg acttatgcgg tggcttatgc
     1741 atctggtatg gctctatttc aactgttttg atgctcttaa aagctggaga tcatgtgatt
     1801 ttcccattgg aggtctatgg agggacttgt caatttgcga cagctatttt acccaattat
     1861 cagattgaaa caagctttgt agatatggct gatttagcaa cagtaaaagc aagtatcagg
     1921 cctaatacgc gtatgattta tctagagaca ccgtcaaatc cgctcttgaa aatttgtgat
     1981 atttcagagc ttgtgcaact cgccaaagct tatggtgtgc taactgtggc tgataatacc
     2041 tttatgacaa gtttgtatca agaaccctta gctatgggtg tggatattgt ggtagaaagt
     2101 gtgaccaaat ttatcaatgg tcatagtgat gtggtagctg gtttagctgc taccaataat
     2161 gaggctatct acaaccagct caagcttttt caaaaaaact ttggagcaat tgttggggtc
     2221 gaagacgctt ggctgattct tcgtggcatg aaaactatgg ggatccgtat ggaacaagcg
     2281 gtaaaaaatg ctcagcagct cgctaactat ttagcgaagc accccaaagt tcttaaggta
     2341 cattaccctg gcttagacag tcatcctaat cacgataccc acctgcaaca agctaagaat
     2401 ggtggtgctg ttttatcctt tgagttggct tctaaggagg agctgatgac ctttacccat
     2461 cgtattcagt tgccgatttt agctgttagt ctaggtggag tagagtccat tttgtcacat
     2521 ccagcaacga tgtctcatgc ttgtttatca tcacaagcgc ggttggaaca aggggttgtt
     2581 gatggtttgc tgcgcttgtc ttgtggtgtt gaaaatatcg aagacttatt ggccgatttt
     2641 gagcaagcac ttgcttttta agtctatttg tccagattgg ctctgtttac agagcaagtc
     2701 tggctttttt attagctttt tgtgaggatg gttgatgcta aagcagggtt taaaaatagc
     2761 taatcgtctg aagtctcaaa agccaaggtg ctagtcatgt cttgaccatt cctaaaagct
     2821 tcatctcatg ctataataag aagactagat tttttacatg ggagatttca catgacattt
     2881 tacgatcaca ccgctattga acccaaatgg caagcctttt gggcagataa tcacaccttt
     2941 aaaacaggaa cagacgcatc aaaacctaag ttttatgccc tagatatgtt cccataccca
     3001 tcaggagctg gtctccacgt tggtcaccca gaaggctata cagcaactga tattctcagc
     3061 cgtttcaaac gtgcccaagg tcacaatgtc ctccacccaa tgggttggga tgcctttgga
     3121 cttcctgctg agcagtacgc tatggatact ggtaatgacc cagccgagtt tacagctgaa
     3181 aacatcgcga acttcaaacg ccagattaat gctcttggtt tctcatacga ctgggatcgt
     3241 gaagttaaca caactgaccc taactactac aagtggacac agtggatctt taccaagctt
     3301 tatgaaaaag gtctagccta cgaagccgaa gttcccgtta actgggttga agaattggga
     3361 acagctatcg ccaacgaaga ggttcttcca gatgggacat cagaacgtgg cggctaccca
     3421 gttgtcagaa aaccaatgcg ccaatggatg ctcaaaatca ctgcctatgc agagcgcttg
     3481 ctagaagact tggaagaagt tgactggcca gagtcaatca aggacatgca acgcaactgg
     3541 atcggtaaat caactggtgc caatgtaacc ttcaaggtta aggatacaga taaggacttc
     3601 actgtcttta caacacgtcc tgacaccctt tttggtgcaa cttacgccgt tcttgctcct
     3661 gagcatgcct tggttgatgc tattacgaca gctgaccaag cagaagccgt ggctgactac
     3721 aaacgtcaag caagtctcaa atcagacctt gctcgtacag accttgccaa agaaaaaact
     3781 ggtgtctgga caggtagcta cgctattaac ccagttaatg gtaacgaaat gccagtttgg
     3841 attgcggact atgtccttgc cagctacggt actggtgcta tcatggctgt tccagcccac
     3901 gatgaacgtg actgggaatt cgcaaaacaa tttaacctag acatcatccc tgttcttgaa
     3961 ggtggtaatg ttgaagaggc tgcctttaca gaagacggtc ttcacatcaa ctccgacttc
     4021 ctagatggtc ttgacaaagc gtcagctatt gctaaaatgg tcgaatggct tgaagcagaa
     4081 ggcgtcggta atgaaaaagt gacttaccgt cttcgtgact ggctctttag ccgtcaacgt
     4141 tactggggtg agccgattcc aattattcac tgggaggatg gcacctcaac agcggttcct
     4201 gagagtgagt tgccactggt tcttccagta actaaggata ttcgtccttc aggtactggt
     4261 gagagcccac ttgctaacgt gacagactgg ttggaagtga ctcgtgaaga tggtgttaaa
     4321 ggtcgtcgtg agactaacac tatgccacaa tgggcaggtt caagctggta ctatctccgt
     4381 tacatcgatc cacacaacac tgaaaaactg gctgacgagg aactcctcaa acaatggttg
     4441 ccagttgata tctatgtcgg tggtgcagag catgccgtgc ttcaccttct ctacgctcgc
     4501 ttctggcaca aggttcttta cgatctcggt gtcgtaccaa ccaaagagcc attccaaaaa
     4561 ctctttaacc aagggatgat tttgggaaca agctaccgcg acagccgggg agcgcttgta
     4621 gcgactgaca aggttgaaaa acgtgatggc agcttcttcc atgtggaaac tggtgatgag
     4681 ctggaacaag caccagctaa gatgtctaaa tcacttaaga acgttgtcaa cccagatgat
     4741 gttgttgaac agtacggtgc tgacactctt cgtgtttatg agatgttcat gggaccactt
     4801 gacgcttcca tcgcttggtc tgaagaaggt cttgaaggct cacgtaagtt cttggaccgt
     4861 gtttaccgtt tgatcacaac taaagagatc actgaggaaa atagcggagc ccttgacaag
     4921 gtttacaacg aaactgttaa ggctgttact gagcaagttg accaaatgaa attcaacaca
     4981 gctatcgctc aactcatggt atttgtcaat gcagccaaca aggaagacaa actctttagc
     5041 gactatgcca aaggcttcgt tcaattgatt gcaccattcg caccgcactt aggtgaggaa
     5101 ctctggcaag ccttgacagc ctcaggtgag tcaatctctt acgtgccatg gccaagttat
     5161 gataaaagca aattggttga aaacgatgtg gaaatcgttg tccaaatcaa aggtaaggtc
     5221 aaagctaaac ttgtcgttgc taaagacctt tcacgcgaag aattgcaaga agttgctctt
     5281 gctaacgaaa aagtccaagc cgaaatcgca ggcaaagaca tcatcaaagt catcgcagta
     5341 ccaaacaaac tcgttaatat tgttatcaaa tagtttgagg tgacacagcc cttcagtggt
     5401 tatttgcgtc acgtcacagt taatgccaaa gagctgatct attcaaaaag caactcatct
     5461 agaaaaacca caagaacgaa ggttcttgtg gtttttaatc gttgtttagg gttattttct
     5521 ccttattatt aagtgtagtt aaattttaaa ataagttaac ttaagtctaa tattgaacac
     5581 ttctttgtgt gatagttggt cttttttaaa acgctttcat tacctataat gaacatataa
     5641 acactttatc tttattaact ttgaaaagag gtagttctta tggaaatgct cctagctccc
     5701 ctaaactggt tctcgcaaaa tattttgcaa aacccagcgt tctttgtagg tcttttggtt
     5761 ttaatcgggt atttactcct taaaaaaccc atttatgagg tctttgctgg ttttgtaaag
     5821 gctaccgttg gttacttgat tttgaacgtt ggagcaggcg gtcttgtaac gacttttcgt
     5881 ccgatcttgg ttgctcttgc caagaaattt gaattgaaag ccgccgttat tgatccttat
     5941 tttggtttgg ctgctgctaa tactaagtta gaagagatgg gcttcatcag tgttgctacg
     6001 acagctctct tgattggatt tggggtcaac attcttctcg ttgcacttcg caaggtcact
     6061 aaagttcgta cccttttcat cacaggtcac atcatggtcc aacaggcagc gacgatttcg
     6121 gtctttgtcc ttcttttaat ccctcaattc caaaatgctt ttggggcatg ggcagtcggt
     6181 atcatctgtg ggctttactg ggcgatcagt tctaatatga ccgttgaagc aactcaacgc
     6241 cttacaggtg gcggtgggtt tgcgattggt caccaacaac aatttgcgat ttggtttgtg
     6301 gataaggttg caccgttctt tggtaaaaaa gaagaaaacc ttgataacct aaaattacca
     6361 accttcttaa acattttcca tgatactgtt gttgcatcag caactttgat gttggtcttt
     6421 ttcggagcta tcttggctgt ccttggtcca gacattatgt ctgatgtgga cttaatcgga
     6481 cctggagcat tcaacccagc taagcaagct ttcttcatgt atattttgca aacctctctc
     6541 actttctcag tttatctctt tatcttgatg cagggtgttc gcatgtttgt ttctgaattg
     6601 accaatgcct ttcaagggat ctcaagcaaa ttacttccag ggtcattccc agcggttgac
     6661 gttgcagctt cctatggctt tggttcttca aatgcggtgc tttcaggatt tgcctttggt
     6721 ttgattggtc aattaatcac cattgctctt cttgttatct ttaaaaatcc aatcttaatt
     6781 atcacaggat tcgttcccgt attctttgat aatgcggcaa ttgcggttta tgcagataaa
     6841 cgtggtggct ggaaagcagc ggtagctctc tcatttatct caggtatttt gcaagttgca
     6901 cttggtgctg ttgctgtagg tcttttagga cttacaggtg gttatcacgg taatatcgac
     6961 ttggttcttc catggttacc atttgggtac ctcttcaaat tccttggtat tgcagggtat
     7021 gtgcttgttt gcatcttctt acttgccatt ccacaattgc aattcgcaaa agctaaggac
     7081 aaagaagctt attaccgtgg ggaagctcaa taacactgca tcttaagaaa tagctctgct
     7141 attctaacaa aataataata aaacattttc ggaggaaaaa acaatggtta aagtcttaac
     7201 agcatgtggc aatggtatgg ggtcatctat ggtgatcaaa atgaaagttg aaaatgcgct
     7261 tcgtcaactt ggtgtgacag atattcagtc agcttcttgc tcagttggtg aagctaaagg
     7321 tctagcttct ggttatgata ttgtagtggc atcaaaccac ttgattcatg agcttgatgg
     7381 tcgtaccaaa ggccacttgg ttggtcttga taacctgatg gatgataatg aaattaaaac
     7441 caaactacaa gaagtgctat aagctaattc tgaatcaaaa cgaaggagtt gtgacgaagg
     7501 ttttcagctc tttctcttta gtaggataaa actagtaaaa atggtgtgtg ttgcaaagca
     7561 agacactaga aagagatagt ttttatgaat ttaaaacaag cctttattga caacaactcc
     7621 atccgattgg ggctaagtgc tgatacttgg caaggggctg ttcgattagc tgttcaacct
     7681 ttgattgata gcaaagcagt gacgtcagct tactacgacg ccatcattgc atcaacagaa
     7741 aaatacggcc cttattatgt gttgatgcca ggtatggcta tgccccatgc ggaagcaggt
     7801 ttaggcgtta atcgcaatgc atttgctttg attacactaa caaaaccagt caccttctca
     7861 gatggtaaag aggtttctgt tcttttgacg ttggccgcta cagacccttc tattcacaca
     7921 acagtggcta tcccacaaat tgtggccttg tttgaactag ataatgccat tgaacgcttg
     7981 gtggcctgcc aaagtcctaa agaggttcta gaaatggtag aagaatctaa agatagtcct
     8041 tacttagaag gtatggactt gaatgcttaa gctttcctta cacaggatac taacgaatga
     8101 tggaaaggat aagaactctt aaccagtttg cacggtggct aagagtttta ggaaaaagag
     8161 atgacacata ttccaaattt acaagttgct ttagaccatt ctgacttaca gggggctgtt
     8221 aaagcagccg ttgctgtggg tcacgaagta gatgtgattg aagctggtac cgtttgtttg
     8281 cttcaagtgg gaagcgaact agttgaggta ttacgcagcc tcttcccaga gaaaattatc
     8341 gtagcagata tcaaatgtgc tgacgctggc ggtacggtcg ctaaaaacaa tgcaaaacgt
     8401 ggtgctgact ggatgacctg catttgctgt gcgacgattc caaccatgga agcagccctc
     8461 aaagccataa aagaagtgcg cggtgaccgt ggggaaattc aaatcgaact ttatggtgat
     8521 tggacttatg agcaagctca attatggctt gacgctggga tttcccaagc gatttaccac
     8581 caatctcgtg atgcccttct tgctggcgaa acttggggtg aaaaagacct taacaaggtg
     8641 aaaacattga ttgacatggg ctttcgtgtc tcagtaactg gagggcttga tgtagacact
     8701 ttgaaacttt ttgaaggggt ggatgtcttt acctttatcg cagggcgagg cattactgaa
     8761 gcagaagatc ctgctgcagc ggcgcgtgcc ttcaaagatg aaatcaaacg tatctggggg
     8821 taactttatg gcgcgtccta ttggtattta tgaaaaagca acgccaaaac agtttacctg
     8881 gcgtgaacgc ttgcaatttg caaaagactt aggttttgat tttgtggaaa tgtctgttga
     8941 tgaatcagat gctcgcttag cgcgcttaga gtggactaag gaagaacggc ttgatttagt
     9001 gaaagccatt tatgaaacag gcattcgcat cccgaccatt tgtttttctg gtcatagacg
     9061 ttacccacta ggctcaaatg attctgctac tgaagccaag tctcttaaac tgatgaaaca
     9121 atgtattgaa ttggcacagg acttaggcgt tcgtaccatt caattagctg gttatgacgt
     9181 ttactatgaa gaaaaatcgc ctgaaacccg tgctcgtttt atcaaaaact tgagacaatc
     9241 ttgtgactgg gccgaagaag cccaagtgat actttctatt gagattatgg atgacccttt
     9301 tatcaactct attgagaaat acttggcagt tgaaaaagag attgactcgc cttatctctt
     9361 tgtttatcct gatgcaggca atgtttctgc ctggcataat gatttgtgga gtgaatttta
     9421 caatggtcac aagtccattg cagctctcca cttgaaagat acttatgctg tcacggaaac
     9481 ctcaaaaggg cagtttcgtg atgtgccatt tggtcaaggt tgtgtggact ggcaagagct
     9541 gtttgcggtc ctcaagaaaa ccaactacaa tgggcctttt ttgattgaaa tgtggtcaga
     9601 aaattgtgac acggtggagg aaacaagggc tgctatcaaa gaagctcagg acttccttta
     9661 cccacttatt gagaaagcgg ggttgacata atatggcgaa aaacttgcaa gaaatgcgtg
     9721 aacgtgtctg tgcggctaac aagtctctac cacaacacgg tcttgtcaaa tttacgtggg
     9781 gcaatgtctc tgaagtttgt cgtgaattag gacgtattgt catcaagcct tctggggtgg
     9841 actacgacct cttgacacca gaaaatatgg ttgttacaga ccttgatggg aatgtggtcg
     9901 aaggtgattt gaactcttct tcagatctgc caacccatgt ggaactttat aaagcttggc
     9961 cagaagtggg cggtattgtc cacactcatt caacagaagc tgtcggttgg gcacaggcag
    10021 gtcgtgatat tccgttttat gggactacgc atgctgacta cttctatgga ccagttccgt
    10081 gtgctcgttc tctcacaaaa gcagaagttg atggggctta cgagcaagaa actggcaacg
    10141 tgattttgga agaatttagc aagcgaggct tagatcctat ggcggttcca ggaatcgtgg
    10201 tgcgtaatca tggcccattt acgtggggga aaaccccaga gcaagccgtt taccactcgg
    10261 ttatcttaga agaagtggct aaaatgaatc gcttgacaga acaaatcaat ccacgcgtag
    10321 agccagcgcc acgatacatt atggataagc attatttgcg taaacatggc ccaaatgctt
    10381 attacggtca aaaatgaggt cgcgatatgg cttattagca caggttctca ctagaagcca
    10441 aaaagttcaa ggttttgtta atcattgttt gggcaagtcc ttttgacttg tccttttcga
    10501 tgaactgttt aaacgccaat gagcacaaac tggatgaacc gtatgttgtg gagttcttag
    10561 agaccagata taaggtgttg gtgttggatc agttgaggtg attagctcga atcatattaa
    10621 gtgaatctta ttatggtgag tttttcaaaa cttggctgcg cagtcactga aatcatgata
    10681 aaataagcaa ggatggattt tcagagagga ggtttgtaaa catgatgatt ttagataaaa
    10741 agagttatga cttgctgtct tatttactta aactagaaac acctgagaca gttatggcca
    10801 tttctcatgc tttaaatcag tcacgtcgta aagtttatta ccagcttgac aaaattaatc
    10861 aggctttgcc aaagggagta gatcagatta tctcttatcc tagacttggc attcttttaa
    10921 cggcggatca aaaagctgct tgtcgcttat tattagaaga agtgactgat tacaattatg
    10981 tcatgaaaag tgatgagcgc agacgactat cctcgattta tattgcggtt tccactgagc
    11041 gcgtgaccat tgataaactg atgcagatca atgatgtgtc tcgtaacacg attttaaatg
    11101 acctgactga gttaagggaa gaactggaag acaaacaata caagattcag cttcatgcga
    11161 caaaggctag gggatattat tttggttgtc atccaatggc tcttattcaa tacctgtaca
    11221 aattgttagt ggacgtttac caaggtggca atactagctt tattgatata ttcaaccgta
    11281 aactctcaga gatacaaggc ttatcggttt atttttctaa agatattttg acttattttc
    11341 atgagtatct ttttttatct caagctagtt taggaaagac aattaatacc caagatagcc
    11401 aattcatgtt gcagatttta cctttcatgc ttttaagtta tcgtaatatg cgtcttgatt
    11461 cagaaacaaa gtctgctctt aaacaagaat ttcatttgat ttggaaacgt aaagaatatc
    11521 acattgctca ggacttagct agagagcttt accataattt taagcttcat ttggatgata
    11581 tcgaagttag tatggtagcg atgttgatgt tgtcttttcg aaaagatcaa gatcatcacg
    11641 tggaaagtca agattatgat gacatgcgag caaccattag tcactttatt gaccagttgg
    11701 agagccgtta tcagttacat ttcacgcata aacaggattt gctgaagcag ttgacgaccc
    11761 actgtaaggc gctcgtttac cgtaaagctt atgggatttt tttagttaat cccttaacag
    11821 accatattaa agaaaaatac gaagaattgt ttgctatgac tcaatcttgt gccactattt
    11881 tggaacaaga ttggacgatt agcttgacag acgatgatat tgcctacttg actatccatc
    11941 ttgggggaga gctgcgtcac aataatacag agcaagaaaa gaccaaactc gttattgttt
    12001 cagatgatgg gataggcatt caaaagttat tgttcaaaca gtgtcaaagg tatctagcaa
    12061 atggtcagat tgaagctgtt tttacgacag aacagtatca gagtgtttac gatcttttag
    12121 cagtcgatat gattgttgct actacagata cgctaaagac taaaatcccg atgcttattg
    12181 ttaaccctat tttaagtgac gatgatatca tcaaattgat acgcttttca aagcaaggac
    12241 gcttgagtga gcactcccgc ttttctacag agctcacaaa agctattgaa gctgttgtaa
    12301 aagatgaatc agatcgttat gccttggttt ctaaaattga aaaactcatt catcgcgagc
    12361 tgctatgagt aagtgttaag tcgtcaaagt acctcagttt tctatgacat agaaaaatat
    12421 aactgaggtt tttaatatag ctttgaatac agtattgatg cgagatacag tgtgcaaaat
    12481 gagacagtat tagactgagc taatgaaaaa gtcagtccac ttttgaacac agatctgtgt
    12541 gacacttggt ctttttatca ttgacaagaa agtctatact taaagtatag aaacgaagaa
    12601 caaattcgga ggaaacccta atgactaaag tacaagatat tacacgtgaa tcatggatcc
    12661 ttaacacgtt tccagaatgg ggaacatggt taaatgaaga aatcgagcaa gaagtcgtgc
    12721 cagctgacaa ctttgcgatg tggtggttag gaaactgtgg tatctggatt aagacaccag
    12781 gcggtgctaa tgttgtcatg gacttatggt caaatcgtgg gaaagcgacc aagcaagtta
    12841 aggatatggt tcgtggacat caaatggcta atatggcagg agctcgtaaa ttacagccca
    12901 atcttagggc ccaaccaatg gtgattgatc catttatgat taatgagttg gattattatt
    12961 tggtttctca ttatcatagt gaccacatcg atatcaatac tgcggcagcc attatcaata
    13021 acccaaaact taatcatgtt aaatttgtag gaccttatga atgtggtgaa gtttggaaaa
    13081 actggggtgt gccaaaagat cgtattatga tcttaaagcc aggtgatagc tttgaattca
    13141 aagatattaa gatcaccgct gtagagtcgt ttgaccgcac ctgtctggta actctcccaa
    13201 tacaaggagc tgatgctcaa gatggtgatt tagcaggttt agctatcaca gatgatgaca
    13261 tggctcgcaa agctgttaac tatatttttg aaacaccagg tggtaccatc tatcacggtg
    13321 cggattctca tttttcgaac tactttgcta aacatggacg tgattatgat attgacgttg
    13381 ttttaaataa ctatggggaa aacccaattg ggattcaaga caagatgact tctgttgacc
    13441 ttcttcgtat ggcagaaaat ctccgtgcta aagtcgttat cccagttcat tatgacattt
    13501 ggtcaaactt tatggcatca acagatgaaa tccttgaact gtggaaaatg cgcaaagaac
    13561 gtctccaata tgatttccat ccctttatct gggaggttgg tggtaagtac acctatccac
    13621 aagaccaaaa tcgtatcgaa taccatcatc ctcgtggatt tgatgactgc ttcttagaag
    13681 attctaatat ccaatttaaa gctttactat aagcaacacc ctactcacct aagatgatag
    13741 tgcctgatta agctaactcg cttcatagga cactgtctta ggtgagtttt ttggagagat
    13801 gagcaaatgt ttaagagtca ccgtggtcgt tatttacgat ggccgcaaaa gagatattat
    13861 aggtaaaaga aggatttcta atgtaacaat agcctaatca gcaaagaaat agtcatcagt
    13921 tgtgataaaa aattgtactg gttaaaagac catacctaaa agaatgaaag cgatcaccta
    13981 tcattgtggc attaccagat cgagttattg tccttgacaa aaagtgacca cacgtgataa
    14041 tatagttatg ttctgtttcg gcagattctt tttttaagta aaaaagtgac cacacgttta
    14101 ttaattgtgt agagctactt tgttaaatat tggctaatat ttcgccaaag ctatgtcact
    14161 atttcacatg ataaacgatt acctaggaga aaaaacgaat ggaaacaatt ttagaagtca
    14221 aacatctcag taaaattttt ggcaaaaaac aaaaagcagc tcttgagatg gtaaagactg
    14281 gcaaaaataa gagtgagatt tttaagaaaa caggcgctac tgtaggtgtc tatgacgcta
    14341 gttttgaggt caaaaaaggt gaaatctttg ttattatggg gctatcagga agtgggaaat
    14401 caacccttgt ccgcatgcta aatcgtttga ttgaaccttc agcaggatct atcttgctgg
    14461 aaggtaaaga catctcaacc atgtcagcag atcagctgcg tgaggtgcgc cgccatgaca
    14521 ttaacatggt tttccaaagc tttgccctct ttcctcataa aaccattttg gaaaataccg
    14581 aatttggttt ggaattacgt ggcgttccca aagaagaacg ccagcgattg gcagaaaaag
    14641 cccttgataa ttcaggccta ttagatttta aagatcagta cccaaaccaa ctatctggtg
    14701 ggatgcagca gcgtgtcggc ctagcccgtg cgctagctaa tagccctaaa attctcttaa
    14761 tggacgaggc attctcagcg cttgatcctt tgattcgtcg tgagatgcaa gatgaattac
    14821 ttgatttgca agatagcatg aaacaaacca tcatctttat cagtcacgac ttgaatgaag
    14881 ccttgcggat tggtgatcgg attgctttga tgaaagacgg acaaattatg caaattggta
    14941 ctggtgagga aatcttgact aacccagcca atgactttgt gcgtgaattc gttgaggatg
    15001 tggaccgttc taaagtcttg acagcacaaa atatcatgat caaaccgtta acaactactg
    15061 ttgaattaga tggacctcaa gttgccttga accgtatgca caacgaagag gtgtctatgt
    15121 tgatggcgac gaatcgccgc cgccaattag tcggtagttt gacggccgat gccgccatag
    15181 aggcgcgcaa aaaagggtta ccgctatcag aagtgattga tcgcgatgtg agaactgtct
    15241 caaaagatac tattattaca gatattttgc ctcttatcta tgattcatct gctccgattg
    15301 cagtgacaga tgataataat cgtctgttag gtgtcattat tcgaggacga gtgattgaag
    15361 ccttggctaa tatctcagac gaagacctta actaaaagga gtgatgcatt ttggaaacga
    15421 tattacaaac aaaattacca gtagctcaac tggtggagca gctaacggag tggctaacta
    15481 aaactttctc aggtctattt gatattatgc aagtagttgg tagctttttg atggattgga
    15541 tgaccaaaac acttttattt atccacccgt tactttttat tgttctagta acagcaggga
    15601 tgtttttcct tgctaagaaa aaatggcctt tgccaacctt taccttgtta ggattgctct
    15661 ttatttacaa tcaagggtta tggaagcagc taatgaatac ctttactctg gtgttagtag
    15721 ctagtttgat ttcggtactt attggtattc cgctggggat ttggatggct aaaaatgcca
    15781 ctgtccgtca gattgtgaat cctattttgg actttatgca aaccatgccg gcttttgttt
    15841 acttgattcc tgccgttgcc ttttttggta ttggtatggt gcctggagta tttgcttcag
    15901 tcatctttgc cttgccccca acagttcgtt ttacaaattt ggccattcgt gacattccaa
    15961 cagaattgat tgaagcctca gatgcctttg ggtcaactgg gaaacaaaag ctcttcaagg
    16021 tagaattgcc tttagctaaa aataccatca tggcgggtgt caatcagacc atgatgctag
    16081 ccctctccat ggtagtaaca ggttccatga ttggtgctcc tggtttagga cgtgaagtct
    16141 tgtcagccct tcaacacgct gatattggta gtggatttgt cagtggtctt gccttggtta
    16201 tcttggcgat tgtgcttgac cgtatgacac agttgttcaa tagcaaacct caagaaaaag
    16261 ccaaagctgg caaaaccaat aaatggattg gtctagcagc ccttgctgtc tttttgatag
    16321 ctgctttagg acgcggtatt atggctatga cttctggtat ggcagataag ggtgaaactg
    16381 ttaacatcgc ttatgtgcag tgggattctg aggttgcctc aactcatgtg attgcagaag
    16441 ttttgaaaaa cgaaggttac catgtgacct tgactccgct tgacaatgcc gttatgtggc
    16501 aaaccgttgc aaatgggaac gctgattttt caactagtgc ttggttgcca gtaactcatg
    16561 ggcaacagta tcagaaatac aagtcaaaat tagatgattt aggacctaac ctaaaaggga
    16621 ccaaacttgg tttagctgtt ccaaaataca tgacagatgt taatagtatt gaggacttaa
    16681 gcaaacaagc cgatcaaaaa atcacaggga tcgaaccagg tgcaggtatc atggcagcag
    16741 cccaaaagac tctaaaagag tatcataatc tatctagttg ggagttagtg gcggcatcaa
    16801 caggagccat gacgacttcc ttggatcaag cgatcaagaa aaaagatcct attgtcgtga
    16861 cagcttggtc accacactgg atgtttgcca agtatgactt gaagtacctt aaagatccta
    16921 aagaaacctt tggctcgact gagaacatca ataccattgc tcgtaaaggc ttgaaaaaag
    16981 atcttccaaa tgtctacaaa atcattgata agttccactg gacccaaaaa gatatggaag
    17041 ctgtcatgct tgacatcaac aaaggcatga gcccagaagc tgccgccaaa aaatgggtag
    17101 aggcaaacca atctaaagta tcaagttgga caaaataagt gcttttgtct aaatagcaaa
    17161 tagagaagtc taggaatttt cctaggcttt ttaggttaac tatttactta tcagcaaaac
    17221 caatggctta aaggagaaaa gcccgtccct ctgtgttata ataaggctat ggaaaacaag
    17281 aataaattac tattaattga tggctcatct gttgcctttc gtgccttttt tgccctctac
    17341 aatcaaattg accgctttaa aaatcatagc ggtctccata ccaatgccat ttatggcttt
    17401 catttgatgc tagaccacat gatgaaaaga gtccagccta ctcacgtgct ggtggctttt
    17461 gatgcgggca aaaccacctt ccgaacagaa atgtatgccg attataaggc gggtcgcgcc
    17521 aagacaccag aggaatttcg tgagcagttt ccttatattc gtgagatgtt gacagccctt
    17581 gggattgctt attatgagtt ggaacactac gaagcagacg atattatcgg gacgcttgat
    17641 aaaatggcgg agcgcacaga agtgcctttt gatgtgacca ttgtcagtgg tgataaagat
    17701 ttgatccagt taactgacga aaataccgtg gttgaaattt ctaaaaaagg ggttgccgaa
    17761 tttgaagaat tcacaccggc ttacctcatg gaaaaaatgg gcttgacgcc aaaccagttt
    17821 attgacctca aagccttgat gggagataaa tcggataaca ttcctggagt gacaaaaatt
    17881 ggagaaaaaa caggccttaa gctccttcat gaatttggta gtttggaagg catttacgag
    17941 catattgatg gattcaaggc ctcaaaaatg aaagaaaact tgatcaatga ccgtgaccaa
    18001 gctttcctat ctaaaacgct cgccactatc aatacagcat ctcctatcac aattggctta
    18061 gatgatattg tctacaatgg tccagatgtt gttagcctct ctcaatttta cgatgagatg
    18121 gattttgtgc aactcaagaa aggtcttgct agccagatgc ctcaagagcc agtagctgcc
    18181 atttcctatc aagaagtgac caatgtgtct gctgatttgt ttagcgcaga agacatcttc
    18241 tactttgaaa cgcttcggga taattaccat cgtgaggcca tcattggttt tgcttgggga
    18301 catggtgagc agatttacgc atccactgac cttagcctat tagcgacgga tagttttaag
    18361 caggtcttcc aaaaacccat tgccacttat gattttaaac gtagcaaggt cttgttgagc
    18421 tacttaggaa ttgagttggt agcacctagc tatgatgcta gattagctaa ttaccttctg
    18481 tcaactgtag aagataatga gcttagcacc attgcccgca tttttactga catctctttg
    18541 gaagaagacg atacagtcta tggtaaaggt gctaaacggg ctgttcctga taaagacgtt
    18601 ttactagaac acttagctcg taaggtcaaa gtattattag atagcaagtc tcaaatgcta
    18661 gacaagctca ctgcccatga gcaactagac ctctatcaga atattgaatt gcctttggct
    18721 aatgtccttg ctaaaatgga aattgaaggg atcaaggtta atagggcgac tttgcaagat
    18781 atggcagagc aaaacaaggt cattattgaa gcgctcaccc aagagattta tgatatggct
    18841 ggccaagaat ttaacattaa ttcgcctaaa cagctgggca gtatcttgtt tgagaagatg
    18901 caactacctc ttgagatgac taagaagacc aaaacaggtt attctacagc tgttgatgtt
    18961 ttggaacgtt tggcaccgat tgctccaatt gtggctaaaa ttttggatta ccgccagatt
    19021 actaaattgc aatccaccta tgtgattggt ttacaggatt atattctggc tgatggcaag
    19081 attcataccc gctatgtgca ggatctcacc cagacagggc gtttgtctag tgtggaccct
    19141 aatcttcaaa acattcccat tcgtttggaa caggggcgtt tgattcgtaa ggcctttacc
    19201 ccatctcatg aagatgccgt cttgttgagt tcagattact cacagattga attgcgggta
    19261 ctggcacata tttcagggga tgagcatttg attgctgcct ttaatgaagg ggcagacatt
    19321 catacctcaa ctgctatgcg tgtgtttggg attgacaagg cagcagatgt tactgccaat
    19381 gaccgccgta atgccaaggc tgttaacttt ggaattgtgt atgggatttc tgattttggt
    19441 ttgtcaaata accttggtat cacccgtaaa caggccaagt cttacattga tacctatttt
    19501 gaacgctatc ctgggattaa agcctatatg gaaaatgtgg tgcgtgaggc taaagacaag
    19561 ggctatgtag agaccctctt taagcgtcgt cgtgaattac cggatatcaa ctctcgtaat
    19621 ttcaacgttc gctcttttgc ggagcgtaca gccatcaact cgcccattca aggaagcgca
    19681 gctgatattc tcaaaatcgc tatgattaat ctggataagg ccttgcaagc aggtggtttt
    19741 agagctaaaa tgctgcttca agtgcatgat gaaatcgttt tggaagtgcc aaatgatgag
    19801 ttgactgcta taaaaaaact tgtcaaagac accatggaag ctgctgttga tttagctgtt
    19861 cctttatgtg tcgatgaaag tactgggcag agctggtacg aagccaaata agttttctta
    19921 cttgttattt ctcattttga caacttatgt tataataaac taaaaaattg taggagaagt
    19981 catgaagctg ctttgagctt tttgacggat aaggttaaaa gtgattgaag ccatgcttta
    20041 ggagttatcc tgctatattg aacagctgta gaggttatta aaatagatag gggaacaagt
    20101 gatttattcg tttcaaaatc cctcagagga tgtcctaaaa gcttacttgg agtcagccaa
    20161 aaccattgcg gttgttggtc tttctgaccg caaagacaca gcagcttatg gtgtcgccaa
    20221 atttatgcag gctatggatt atcggatcat tccagtcaat cccaaattag caggtcagct
    20281 tattttggga gagaaggtct atgccagtat caaggcaatt ccctttgagg ttgacattgt
    20341 agatgtcttt cgcagaagtg agtttttacc agaagttgcc agagactttt tagcaggtca
    20401 ggccaaagtc ttttgggcgc aattaggcct tgaaaaccaa gaagcacaaa ccattttacg
    20461 gtcggcaggc aaagaggcta ttgtgatgaa tcgctgccta aaaatagact atttgcaatt
    20521 agtcgctaaa ccagaatgca tcacaaatca ttgaaactag agacgtgcgt gataataaag
    20581 gaaaaaagga taggagtagc agcttatgga cattcattca catcagcaag ccctagatgc
    20641 ctatgaaaat gtcctagagc atctacggga aaaacatatt cgaattacag agacacgtaa
    20701 agccattatt tcttacatga ttcagtccac agaacaccct agtgccgata agatttaccg
    20761 tgacttacag cctaactttc ctaacatgag ccttgccaca gtctataata atttgaaagt
    20821 tttagttgat gaaggttttg tctcagaatt gaaaatcagc aatgatttaa ccacctacta
    20881 tgactttatg ggccatcaac acgtcaatgt ggtttgtgaa atatgtggga agattgctga
    20941 ctttatggat gttgatgtta tggatattgc caaagaagcc catgagcaaa caggttataa
    21001 ggtcacgcgt atcccagtta ttgcttacgg gatttgtccg gattgccaag caaaagatca
    21061 acctgatttt tagagttaac ccttaaataa aggcattata aatatagtgc ctttacaaat
    21121 caaaaacccc cagttcacta ccagaccttt gttgcttacg ttaaagagtt atttgctggg
    21181 gatcataagg aattaaagga aagaaccatc aatcatctcc tctattgttt gttcctcacc
    21241 tgggaaaatc tctttcttac aaatcaatcg cgtcgtcgct tgaaactatt agtggttgag
    21301 agaagttata acaatgttgg caacttctta aaagagtatt ttggaggatt ttttgagatt
    21361 gtcaactttg atgacttgag gctgaccatg gttgatatgg tgtcactgtc ttcagagtat
    21421 gacgtaattg tgacagatat gattcttgag caaacaacgg actccgaaat tttatttttc
    21481 aatcagatgg cccctagtgt ggtggcgaat agattgacag acatgtaact aaacaatgat
    21541 aatatctgtg agagcatcgg aatttaaaaa atgagcgata aataagatta agaataagtt
    21601 agacttacaa ggagtagagt ctattacctt gaaaaagaaa agcaaggttt aattattcaa
    21661 cttgaaaaat taaaaaacaa aaagctcgaa aaagagattc ttagtgaatc tatgtattaa
    21721 tatttttaaa tgcataatga ggaagtttag tgaaaaagta tttaa
//
LOCUS       DAUNLR010000025        21453 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUNLR010000025 DAUNLR010000000
VERSION     DAUNLR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21453
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.025"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..283)
                     /gene="cadX"
                     /locus_tag="VLL59_001029"
     CDS             complement(<1..283)
                     /gene="cadX"
                     /locus_tag="VLL59_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HER6509158.1"
                     /translation="MKKDSICQVNVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLTVEELCVCDIACLLNLSMASASHHLRKLANQNILGTRREGKI"
     gene            complement(295..909)
                     /locus_tag="VLL59_001030"
     CDS             complement(295..909)
                     /locus_tag="VLL59_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HER6509159.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLRK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGEILEKYSRWFIAVVYLGLGIYILIENNSFDMLWAVLG"
     gene            complement(1202..1351)
                     /gene="rpmG"
                     /locus_tag="VLL59_001031"
     CDS             complement(1202..1351)
                     /gene="rpmG"
                     /locus_tag="VLL59_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HER6509160.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(1367..1549)
                     /gene="rpmF"
                     /locus_tag="VLL59_001032"
     CDS             complement(1367..1549)
                     /gene="rpmF"
                     /locus_tag="VLL59_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HER6509161.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            1769..3049
                     /locus_tag="VLL59_001033"
     CDS             1769..3049
                     /locus_tag="VLL59_001033"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HER6509162.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDVYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQELEVSFEDMMTNFANISEQLLS"
     gene            3387..5135
                     /gene="aspS"
                     /locus_tag="VLL59_001034"
     CDS             3387..5135
                     /gene="aspS"
                     /locus_tag="VLL59_001034"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HER6509163.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANAQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            5128..6069
                     /locus_tag="VLL59_001035"
     CDS             5128..6069
                     /locus_tag="VLL59_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HER6509164.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIIPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            6089..6967
                     /locus_tag="VLL59_001036"
     CDS             6089..6967
                     /locus_tag="VLL59_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HER6509165.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            7010..7882
                     /locus_tag="VLL59_001037"
     CDS             7010..7882
                     /locus_tag="VLL59_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HER6509166.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(7909..8217)
                     /locus_tag="VLL59_001038"
     CDS             complement(7909..8217)
                     /locus_tag="VLL59_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HER6509167.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(8305..9996)
                     /locus_tag="VLL59_001039"
     CDS             complement(8305..9996)
                     /locus_tag="VLL59_001039"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HER6509168.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYVQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            10287..10724
                     /gene="argR"
                     /locus_tag="VLL59_001040"
     CDS             10287..10724
                     /gene="argR"
                     /locus_tag="VLL59_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HER6509169.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            10721..11073
                     /locus_tag="VLL59_001041"
                     /pseudo
     CDS             10721..11073
                     /locus_tag="VLL59_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            11060..13615
                     /gene="mutS"
                     /locus_tag="VLL59_001042"
     CDS             11060..13615
                     /gene="mutS"
                     /locus_tag="VLL59_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HER6509170.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCIDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQESGINNL
                     KIDYNKKDGYYFHVTTSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADEVLTRLEAQAQSAEIISVPS
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            13744..15726
                     /gene="mutL"
                     /locus_tag="VLL59_001043"
     CDS             13744..15726
                     /gene="mutL"
                     /locus_tag="VLL59_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HER6509171.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTSDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKVELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLE
                     NEGQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            15737..16957
                     /locus_tag="VLL59_001044"
     CDS             15737..16957
                     /locus_tag="VLL59_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HER6509172.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYCFDETRPETHAFDHGKGLLASFQNYRQVFQDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            16959..17555
                     /gene="ruvA"
                     /locus_tag="VLL59_001045"
     CDS             16959..17555
                     /gene="ruvA"
                     /locus_tag="VLL59_001045"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HER6509173.1"
                     /translation="MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGSTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
                     LALGYKVAELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            17565..18125
                     /locus_tag="VLL59_001046"
     CDS             17565..18125
                     /locus_tag="VLL59_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HER6509174.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVAAFTSEELADALENPSIIRHKLKLAATVNNAIA
                     VQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            18194..19465
                     /locus_tag="VLL59_001047"
     CDS             18194..19465
                     /locus_tag="VLL59_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HER6509175.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLAHETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            19554..20690
                     /gene="recA"
                     /locus_tag="VLL59_001048"
     CDS             19554..20690
                     /gene="recA"
                     /locus_tag="VLL59_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HER6509176.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            20981..21379
                     /gene="spx"
                     /locus_tag="VLL59_001049"
     CDS             20981..21379
                     /gene="spx"
                     /locus_tag="VLL59_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HER6509177.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
BASE COUNT         6426 a         3723 c         4662 g         6642 t
ORIGIN      
        1 taattttccc ctctcttcta gtgcccaaga tgttttgatt ggctagttta cgaagatggt
       61 gggaggcaga tgccatactg agatttagta aacaggctat atcgcagaca cagagttctt
      121 caacagtaag gagataaaag atgatattta tctgtttatt atcggtaaac tttgataaaa
      181 tacgaagtga tttttggact ttttcctttt caaggtagtt cgttgcggtt gtaacatttt
      241 gttgatttat aacattcact tggcagatac tatctttttt cataatattt tctcctagcc
      301 taacacagcc catagcatgt caaaactgtt gttttcaatc aggatatata tccccaatcc
      361 taaataaaca acggcaataa accatctgct atatttttcc aaaatttctc caacagaagg
      421 gacttgtgcc aatttttggg cagaaaaaac caagagataa atcatgacta gaaaggtaag
      481 taaagccact atcaaattcg ctaaatttaa ggtagtaaaa tacgggacaa agacaccaat
      541 attgtcagca ccacaacttg caaaagtaat catagcgact agaaaaatca ggtttttatt
      601 atctttgcgc aaaccttctt tggcaatagc ttctccatca gaatctccta aaagcaaaac
      661 tttgaggcct aggaaaattg gaatcaaacc gagcaaacct aaaatctctt tactaggaat
      721 ataatctaag acaaatgcaa aaagcaaact tagcaatatt agactaacag agcctagaaa
      781 ttgtcctaaa tagatgttaa tgatgtcttt tctgcttttt cttttggcaa aaaataacat
      841 taggataata agtaagtcta cggctgtccc agaatacagg attattgaag taacaacatt
      901 ttgaatcata aaacacctca ttcaaatgta tttttgaatg tatattaaca ttaaacttta
      961 tagatgtcaa cttcagctcc accaaaatat agataagtag ttagtgtacc aaatattaaa
     1021 aagccctgcc atcgaaatga taacagggcc taacttcaat atccaaatga tagattcatc
     1081 taaaaaaggt agagtaaaag gtagagtttt tattgattta tattgcaatg taatgaactt
     1141 caaaatttca aaaatcgctt aaaatcaatg atttgacgtc taatgacgtg tagtgaaccc
     1201 cttacttaac ctctgtaaat gtaacgtgtt tacgtaattt tggtgagtat tttttcaatt
     1261 gaagacggtc tggagtgtta cgtttgtttt ttgaagtaag gtacaagcgt tcaccagatt
     1321 ctttgtgttc aagtgtaata tttacgcgca tggtatctcc cttctattat ttagcttcgt
     1381 tagctttagc gattttacgt cctttgtagt atcctttaag ggatacacgg tgagaacgtg
     1441 agtaatctcc agtagtttcg tcgaattgta cagatggagc tgtcaatttg tagtgtgtac
     1501 gacgtttgtt tttcttcgct tttgacgtgt gacgtgcagg tactgccatt ttcttgttct
     1561 tcctttcgat gtgtaagttt tgattttcat caacttcact atgataacat atcttttttg
     1621 taaagtaaag ttacttgaca aaacttttta tttttacaat ttcatggtga aaatactatc
     1681 aaactaaagc aaatgatata tgcttgttta aaatataaga aaaaatggta gaatgtttaa
     1741 agagaaaact aatcaaagag gtaaacttat gaaacttcaa aaaccaaaag ggactcagga
     1801 tattctgcct ggggatgctg cgaaatggca gtatgtggaa tctgttgcgc gtgatacgtt
     1861 tagccaatac aattatggag aaattcgtac tcctatgttt gaacactacg aggtaatctc
     1921 gcggtctgtg ggtgatacga ctgatattgt gacgaaggaa atgtatgatt tctatgataa
     1981 aggagatcgt cacattacct tgcgaccaga gggtacagct ccagtggtgc gttcttatgt
     2041 tgaaaataaa ttgtttgcgc cagaggtcca aaaacccgtc aaactttatt atatcggttc
     2101 catgttccgc tacgaacgtc ctcaagctgg tcgtttacgt gaatttcacc agattggggt
     2161 agaatgtttc ggcgctgcta atccagcaac agatgttgaa accattgcga tggcctatca
     2221 cctctttgaa aaattgggca ttaaggatgt cacccttcat ttaaatagtt tggggagtcc
     2281 tgagagtcgt gcagcttatc gtcaagcctt gattgactac ttaacaccaa tgcgtgatca
     2341 attatctaaa gatagtcaac gtcgcttgga tgaaaaccca ctgcgcgtgc ttgattctaa
     2401 agaaaaagaa gataaactag ccgttgaaaa ggcgccttct attttggatt acttagatga
     2461 ggaaagtcag gcgcactttg aggcggtcaa agatatgctt gaagcacttg acattcctta
     2521 tgtgattgac accaatatgg tgcgtggcct tgattactat aaccacacta tttttgaatt
     2581 catcacgtct gtggagggct ctgacttaac catctgtgcg ggtggacgtt atgatagttt
     2641 ggtaggttat tttggtggac cagaaacccc tggctttggc tttggtcttg gtttagaacg
     2701 tctcttgatg attattgaaa agcagggcat taccttgcca attgagacag agatggatgt
     2761 ttaccttgct gtgttaggtg atggtgctaa tagcaaagct ttagaattgg ttcaagccat
     2821 tcgccgtcaa gggtttacag ctgaacgaga ttaccttggc cgtaagatta aggctcagtt
     2881 taaatcagcc gataccttta aagcaaaatt ggtaatgact ttaggagaaa gtgaagttga
     2941 agcaggcaaa gctgtgatta agaataatcg tagccgccaa gaattggaag tcagttttga
     3001 agatatgatg acaaactttg caaacatctc agagcaatta ttgtcttaat gattttattg
     3061 tcgtcataag cttttgttga tatgattgtt tagaagataa tcactaaaac aggtgtaact
     3121 tcccttttta gaagggagtt gcacctgttt gttttctgta aggggattga ttagctttct
     3181 tagtattctg tgaggacacc tgatatgtca aaatactgac ggctcagtat tcttgcttta
     3241 tctttagaaa aactcttttt aaatgggtgg ggtttttaag ggctttttgc tataatagta
     3301 gggaatgaat taattgattt atatagtgaa aggaattgga aacgagcagg tttcacagga
     3361 ttctgtttgt tttagggaat ttatttatga aacgtagcat gtatgcaggt cgtgttcgcg
     3421 aagaacacat tggaacgaca atcacattga aaggatgggt cagtcgtcgt cgtgacttgg
     3481 gtggtctcat ctttattgat ttgcgtgacc gtgagggtgt gatgcaatta gtcattaacc
     3541 ctgaggaagt ttccagtgat gtgatggcaa ctgctgaacg cttacgtagt gaatatgtga
     3601 ttgaagtgga aggttttgtt gaagctcgac aacaagccaa tgataagttg gcgacaggaa
     3661 tggttgagtt aaaagtatct gctttgacca ttttaaacac agctaaaacg acgccttttg
     3721 aaattaaaga tgacgttgaa gtaagtgatg acacgcgttt acgttaccgt tacttagatt
     3781 tacgacgtcc agaaatgtta gaaaacttca agctacgtgc aaaagtgact cattctatcc
     3841 gtaattacct tgatgacctt gagtttatcg atgtcgagac acctatgttg acaaaatcaa
     3901 ctccagaagg tgcgcgtgac tatctggtac caagtcgtgt tagccaaggg catttctatg
     3961 ctttgccaca aagtccgcaa ataaccaaac agttattgat gaatgctggc tttgatcgct
     4021 attatcaaat tgtgaaatgt ttccgcgatg aagatctacg tggtgaccgt caacctgagt
     4081 ttacacaagt tgacttggaa acgtcattcc tttctgaaca agaaattcaa gacatcgttg
     4141 aaggcatgat tgctaaagtg atgaaagaga caaaagaaat agacgtaacc ctaccattcc
     4201 cacgtatgag ctacgatgta gcaatgaata gctacggctc tgataaacca gacacacgtt
     4261 ttgaaatgct tttacaagac ttgacagtaa ctgtcaaagg aattgacttc aaggttttct
     4321 cagaagcacc agctgtcaag gcgattgtgg tgaagggaaa tgcagatcga tactctcgta
     4381 aagatattga caaattaact gagtttgcca aacaatttgg tgctaaaggc cttgcctggg
     4441 ttaaggtgac agatggtcaa ttggcaggcc cagtagccaa gttcttgaca gctattgaga
     4501 cagagttgtc aagccaatta aaacttgctg agaatgatct agttttattt gtagcggata
     4561 ctcttgaggt tgctaataat acattaggtg cccttcgtaa tcgtattgcc aaggaccttg
     4621 acatgattga tcagtcgcag tttaatttcc tttgggtggt tgattggcca atgtttgagt
     4681 ggtcagaaga agaaggacgt tatatgtcag ctcatcaccc attcactctt ccaacgccag
     4741 aatctgctca tgagttagag ggtgatttgg ctaaggtacg ggctattgct tacgacatcg
     4801 ttttaaatgg ttacgagctt ggtggtggta gcctgcgtat caatcaaaaa gagatgcaag
     4861 agcgcatgtt caaggctctt ggctttaccg ctgatgaagc taacgcccaa tttggtttct
     4921 tactagaagc gatggactac ggctttcctc ctcatggtgg cttggcaatt ggtcttgacc
     4981 gttttgtcat gttgcttgct ggaaaagaca atattcgaga agttattgcc ttccctaaaa
     5041 ataacaaagc ctctgatcca atgacgcaag cacctagtct tgtttctgaa aaccaattag
     5101 aagaactcag tcttcaaata gaaagtcatg attaagaaaa caacctataa gaaaaaagtt
     5161 aaatatgtca ttagtagagg ggccaagaaa gttggcctac tccacgctct aagaagtatt
     5221 tcaagagaaa aatatgcaga gaagatttcg gcttctctgc tttatggcat tctctctagt
     5281 attgctgtga attttttctt ccagcctggg catgtttatt caagtggagc aactggtcta
     5341 gcacaggttt tttcagctct tagtcatcgt cttttaggct atgattttcc catcgccttt
     5401 gcgttttatt tgattaatat tcctttgctt attttagctt ggtataaaat tgggcatcaa
     5461 tttaccattt ttacctttat cacagtcagc atgagttctt tctttattca aatcatacct
     5521 caagtgacgc tgacgactga tcctcttatc aatgctattt ttggtggttt ggttatggga
     5581 atgggaattg gtacaggtct caaatcacgt atctctagtg gggggactga tattgtcagt
     5641 ttgaccctta gaaaacgaac aggcaaggat gtgggcagtc tctcattgat ggttaatggt
     5701 gcaattttag cctttgcagg gattttattt ggctggcagt acgcccttta ttctatggtc
     5761 tctatctttg tatcaagtcg tgttacggat gccattttca ccaagcaaaa gaaaatgcag
     5821 gcaactattg ttaccagcca tccagagcgt gtgattcata tgatccataa acgtctgcat
     5881 cgcggggtga ccagtatcaa cgacgcagaa gggacttaca agcatgaaca aaaagcagtt
     5941 ttgattacca ttttgacatg tgaagaatac ccagaattca aatggctgat gttaaaaaca
     6001 gacccacaag cctttgtttc agtggctgag aatgttagaa ttatcggtcg ttttgtggaa
     6061 gatgattaag aaaaacacag gaggtgtcat gtcaattgac caacgtttac agttaaagaa
     6121 attttgcttt attattttag gagctgctat ctacgccttt gcttttgttt atttttacat
     6181 ggctaatcgc attgcagcca atggtttagc tggtctcacc ctagttggta aggcactttt
     6241 tgagattgat ccttctttga taggctattt gattaatttg cctttggtct tgctgggagc
     6301 tagatgtttt gggaaaagag ccatggttta cacagtaacg ggtattttat cactttactt
     6361 ttttgtgtgg ctgtttcaac gctttccttt ggtcgttgac ttggaccatg acaatttagt
     6421 cgtttccttg atggctggaa ttattggtgg tctaggtggc ggtcttgtgt ttcgcaatgg
     6481 tggaaccatt ggtggagcag atattattgc taagttatta gaagacaagt taggactaca
     6541 gctgaatcaa gctcttttag gcattgatct ttttgtcatg attgtctctt tgacttatat
     6601 ttccctgccg caaatgatgt atgctctgat tgctagcttt atgtatggtc aaattgttcg
     6661 cttggtacaa caaggtggtt attcagcccg tggcattttt atcgtttcag aacaagcgga
     6721 gaaaattgcc cggttcatca tggacgaatt gggaagagga gttacttatc taacaggtga
     6781 aggagcctac tctggtcgcc gtaaaaaagt gatttatgtg gctttggggc gaagagatat
     6841 tagggaatta aaagcttttt taactcaggt tgatcccaat gcctttatca cttattttga
     6901 tgttaatgaa gtcaatagcc cagaattttt aactattaaa agcaaatacc ataaaaagag
     6961 aaaataaatg agcattagag ttgcctgcga agaatagtga ggataaagga tggcacatca
     7021 cgataaattg actaaactac taaaactgtt tttgattgcc ctaggtgtag ccatttatac
     7081 cttcggtttt gttaatttta acatggctaa tgctttggct gaaggtggtg tggcaggaat
     7141 aaccttgatt ttacacgcgc attttgggat taatcctgct tactcttctc tcttatttaa
     7201 tcttccactt tttattttag gggcaaagat ttttgggaag cgttctttgg ctctaaccat
     7261 ctatggaaca gttctgatgt ccgcttttat ctggatgtgg caaaaagttc ctatcgaact
     7321 tggcttggaa aatgacatga tgttggtggc tgtagtggca ggtctctttt cagggattgg
     7381 gagtggcatt gtttttcgct atggtgcaac cacgggtgga acggatatta ttggtcgcat
     7441 tgcagaagaa aaatttggag ctaagctagg tcaaactttg cttttggtgg atgctcttgt
     7501 attgacagct tcgttgactt atgtggattt aaaacacatg ctttatactt tggtggcaag
     7561 ctttgttttt agccaaatga ttagtgtggt tcaaaatggt ggttacacta tccgtggaat
     7621 gattattatt accaagcatt cagaggctgc cgctcaagct atcctaaccg aaatcaatcg
     7681 tggagtgact tacttgaaag gtcaaggagc ttactctggt aatgattaca atatcatgta
     7741 tgtgaccttg aacccaactg aagttcggga agtcaaacgt attttagctg gtttggatcc
     7801 agatgccttt atctccatta ttgatgtgga cgaagttatt agctctgatt ttaaaattcg
     7861 ccgaagaaat tatgataaat aaaaatacag gtcaaacagc ctgtattttt attttggtcc
     7921 cccacttaag aaactaccaa gcataatagc tgatatagca gttcccttgt aatggctagc
     7981 ttttgttttt accaagcgac taagatcaaa tatgctttta ggagcatcaa attgatgtgt
     8041 taagatgtat tgattgataa gtgagtcaat ttttgtagct aggagtgagc tcatcccctc
     8101 tttttcaagt tgactggcga gctcgaagat cgcttgacga aaataatcat cggcttgtat
     8161 tacttgttcg ctataaactt tactaagagc atctaatatt tctttttctg atggcatggc
     8221 attctcctgt aacatattgt gctattatta taatataaaa aactaagact gtcataaatg
     8281 tgacagcctt agtaatgtta ttacttacat ttcatttggt gcgtcaacac cgagtaagcg
     8341 aagcgcttct ttaagaacag tagcagttgc atagcagaga gctaagcggt tatcacgttc
     8401 tgagttgtcg tcaagaatgc gagtgtgagc ataatatttg ttaaagcttt gggctaagtt
     8461 aatagcaaat ttagccataa tagaaggctc aaagttatct gatgttcgct tgataatgcg
     8521 tgggaaatct tggataagtt tgataatttc ccagctttca gcatcagcta aactgtaagt
     8581 ggtggttgca gatggcgtaa agtcagcttt acgtagaata gattggatac gagcatgagc
     8641 atattgaacg taaggtccag tttctccttc aaaggaaacc atggcttcaa ggtcaaagtc
     8701 atacccattc atacgatctg ttttgagatc gtaaaacttg atggcaccga caccaacagc
     8761 gtgtgcaacg gcttctttgt cagcaaggtt tggatttttc gcttcaattt gagaagctgc
     8821 acggttaatg gcttcagcaa ccgtaggttc aagaagaata acattacctt tacgtgttga
     8881 taatttagca ccgccttttg tgacaagtcc aaaagcaacg tgtgtcatat catctgacca
     8941 atcgtaaccc atttctttta gcactgcttt taattgtttg aagtgagcag cttgctcatt
     9001 accaacaaca taaacggatt tagcaaagtc ataagtgcgc ttacggtaaa gtgcggcagc
     9061 taggtcacgg gtaatgtaaa gagtagcgcc atctgatttt ttgatcaagg cagggtgttc
     9121 aatgccgtat ttttcaaggt taacaacttg ggcaccttta gattctacaa gaaggttttt
     9181 agcttctaat aagtcaagaa cctcatccat tttgtcatta tagaaggcct caccgttgta
     9241 actatcgaag gtgacatgta attggacata aagtcggttg aactcaagta aactttcatc
     9301 acggaaccat tgccataatt cagtagcttc tttgtcgcca tcttccaatt tacggaacca
     9361 ttcacgagct tcttcatcaa cggtgggatc agtttcagct tcagcattga tacgaacgta
     9421 aagttttaag agttcatcaa taggatgtgc ctgaacagca gcttcatctc cccatttttt
     9481 gtaggcaaca atgagcatac caaattgttt accccagtca ccaaggtgat tgatttttac
     9541 aggtttatag cccattttgg caaaaatgtg agcgagacta tcaccaataa ctgttgagcg
     9601 gaggtgaccg attgaaaatg gcttagcgat gtttgggctt gacatgtcaa tagcaacatt
     9661 tcgcccttga ccttcgtctt gctgagcata gtctgaacct gctgtaatca cttgttcaag
     9721 gacctgtgag gaaatcttag ctttatcaag gaaaaagttg atgtaagggc cgacagctac
     9781 gactttttca aattggctct catcaatctg ttcagctaac tcgctagcaa tcatttgagg
     9841 ggctttgcga aggacttttg ctaaactaaa ggctggaaag gcaaggtctc ccatgtcaga
     9901 attttttggg gtttcaagca agttaaaaat agcatcttgt tctaattctg gaacaacttt
     9961 agctatttca cttgcgatta gagttttagt atccatacag cgtctcctaa aaattgtttg
    10021 tcaccctatt ctaacatatt tctttaaaat aaacgaggag aggattgata aattatactg
    10081 aaactttcaa ggaaatgaat tgcttgaggt tgttgttttt ctgaaaatgt tataaaaaga
    10141 gaaatgaggt ttcttttcaa cagttttcaa gtgaaattct agttgaattt gataaaaaat
    10201 tgctgaaaat agctgggcga agatgaaata atacactttt tttgttataa tttgagagga
    10261 taattataca attggggtga tatatcatga ataaaatgga gcgtcaacag cagattaagc
    10321 gaatcattca agcagagcat attggcacac aagaagatat taaaaatcac cttcaaaaag
    10381 aaggcattgt ggtcacccaa gcaactctat ctcgggactt aagagaaatt ggccttttga
    10441 aattgagaga tgaacaaggc aaactctatt atagtttgtc tgaacccgtt gcaacaccat
    10501 ttagtcctga ggtgcgtttt tatgttttga aagttgatcg agcaggtttt atgctggttc
    10561 tccataccaa tttaggagag gctgatgttc tagctaattt gattgacaat gatgccattg
    10621 aagatattct aggaaccatt gctggtgcgg ataccttgct tgtgatttgc agagacgaag
    10681 agattgctaa acgctttgaa aaagatttgg ctgcaggcct atgactagct atcaagagtc
    10741 tttgacacaa ttgattcttg ctatccatga attctagtat cgttgcttat aaagaagtga
    10801 agcaatagct gtctaagctc catgatttta aaaagtaagc ttatcagatg aaacgctatc
    10861 aacaagatgc cctgcttttc aaaaaaaata gataaagaaa aggctgcgac agtatctgca
    10921 agcagggcaa aagaactaga agataggctc agtcatcagc cattaattga tgattatcga
    10981 gaaaagatgc aagatgcaag tgatgtgatt cagtatatca ccaaacgtat agaagatcag
    11041 ttaaacaagg agttaacaaa tggcaaaaac taacatttct cctggaatgc aacagtatct
    11101 ggacatcaaa aaagattatc cagatgcttt tttgcttttt aggatgggtg acttttatga
    11161 attattttac gaggacgctg tcaaagcagc acaactctta gaaattggtt tgaccagtcg
    11221 caacaagaat gcggaaaatc caattcctat ggcaggcgtg ccacatcatt ctgcccaaca
    11281 atacattgat gtgttaattg agttgggtta caaggttgct gtcgcagaac aaatggaaga
    11341 cccaaagcaa gctgttgggg tggtgaagcg tgaggtcgtt caagtcataa ctcctggaac
    11401 ggttgtggat tcagctaagc cagatagcgc caataacttt ttggtagctg ttgactttga
    11461 tggttgccgt tatggattgg cttatatgga tgtatccaca ggtgaatttt gcgtgacaga
    11521 tttggcggac tttacgagtg ttcgtagcga aatccaaaac ctcaaggcaa aagaagtctt
    11581 actaggtttt gatttatctg aagaagaaca gacgattttg gtcaagcaga tgaatttgct
    11641 gctttcttat gaagaaacgg tctatgaaga taaatcttta attgacggcc aattgacaac
    11701 ggtagaactg acagcggcag gaaaactctt gcaatacgtt cacaaaacac aaatgcgaga
    11761 actcagccac ttgcaagcat tggttcacta tgagatcaag gattatttgc agatgtcgta
    11821 tgccactaag tcaagtttag atttggtaga aaatgctagg actaataaaa aacatggaag
    11881 tctctattgg ctgttagatg aaaccaagac agctatgggg atgaggcttt tgcgctcatg
    11941 gattgatcga cctttggttt ctaaagaagc tattttagag cgtcaagaaa ttattcaagt
    12001 ttttctgaat gcttttattg agcgaaccga tttaagcaat agtttaaaag gtgtttacga
    12061 catcgaacgc ttatctagtc gcgtgtcttt tggcaaggca aatccgaaag atttacttca
    12121 attggggcat accttagccc aagtgcctta tatcaaagct atcttagagt cttttgacag
    12181 tccttgtatt gacaaacttg tcaatgatat tgacagtttg cctgagttgg aatacttgat
    12241 tagaacagcc attgatccag atgcaccagc aactattagt gaaggaagta ttatccgcaa
    12301 tggttttgat gagcgcttgg accattatcg taaagtaatg cgagagggga caggctggat
    12361 tgcggatatt gaggccaaag agcgtcaaga aagtggcatt aataacctaa aaattgatta
    12421 caataaaaaa gatggatatt atttccacgt tacgacttca aatcttagct tagtgcctga
    12481 gcattttttc agaaaggcaa ctttaaaaaa ttctgaacgt tatggaacag cagaattggc
    12541 taagattgaa ggtcagatgt tagaggctag ggaagagtca tctagtttag aatacgatat
    12601 ttttatgtgc attagagctc aagttgaaac ctatattaat cgtttacaga aactggctaa
    12661 aactttggca acggtggatg ttttgcaaag tttagcagtc gttgctgaaa ccaatcatta
    12721 tattcggccg cagttcaatg ataatcatgt gattacaatt caagaaggtc gtcacgccgt
    12781 tgttgaaaag gttatgggag tgcaggaata cattcccaat agtatctctt ttgaccaaca
    12841 gaccagtatt cagctgatta caggtccaaa tatgagtggt aagtcgactt atatgagaca
    12901 gctggcctta acggttatca tggcccagat gggttcattt gtggctgctg atcatgttga
    12961 tttaccttta tttgatgcga tttttacgcg tattggggct gctgatgatt tgatttctgg
    13021 gcaatcaacc tttatggtgg agatgatgga agcaaaccaa gcaatcaaac gcgcaagtga
    13081 caactctctt attctatttg atgaactggg acgaggcacg gcaacttatg atggtatggc
    13141 tttagcccag gcaattattg aatatatcca tgatagagtt ggtgctaaga ccatatttgc
    13201 aacgcattat catgaattga cagacttgtc aactaagttg acaagcctag tcaatgttca
    13261 tgtagcaacg cttgaaaaag atggcgatgt taccttcctt cataagattg ctgagggacc
    13321 ggcggataaa tcttacggta ttcatgtagc aaaaatagca ggacttcctg aggccctgct
    13381 aagcagagca gatgaggtgc ttactcgttt agaagcgcaa gcacaatctg ctgagataat
    13441 atcagtccct tcacaagttg agtcaagcag cgctgttaga caggggcaat tatccctttt
    13501 tggtgatgaa gagaaagctc atgagattag gcaagcactg gaagctattg atgtcatgaa
    13561 catgaccccg cttcaagcaa tgacaaccct ttacgaattg aaaaagttgt tatagtcttt
    13621 cagctgaaaa tgaaaaagat gccttcaata tagaaagcat ctttttgttc tgtcaaaaac
    13681 ggtccgaggc cttcggctat ttattaagtg tgttataata gtccataaga atgcgaggaa
    13741 attatgacaa acattattga attaccggaa gttctcgcca accaaattgc agctggtgaa
    13801 gttgtagaaa ggccagcgag tgttgtcaag gaattggttg agaatgctat tgatgctaaa
    13861 agtagccaga ttaccgttga aattgaagag tctggcctta agatgataca ggttacagac
    13921 aacggtgagg gaatgtctca tgaagattta cctttaagtc tgcgtcgcca cgctactagt
    13981 aaaattaaga gtcagagtga tttgtttaga attagaacac ttggcttccg tggagaggct
    14041 ttaccgtctg ttgcctctat cagtaaaatc acgataaaaa cagcaacaaa agaagtcact
    14101 cacggttctc ttcttatagc tactggtggg gaaattgaga cacttgaagc gatctcaact
    14161 cctactggaa ccaaaattaa ggttgaaaac cttttttaca acacgcctgc tcgtctcaaa
    14221 tatatgaaaa gtttacaggc agaattagct cacattgtag atgtggtcaa ccggttgagt
    14281 ttggcacatc cagaagttgc tttcacactg attagtgatg gtcgccaatt aactcagaca
    14341 tcaggaacta gcgatttacg ccaagcaatt gcagggattt atggtttgaa tactaccaaa
    14401 aaaatgctgg ctatctctaa tgctgatttg gattttgaag tttccggcta tgttagcttg
    14461 ccagagttga cacgcgccaa ccgtaattac atgacgattt tggttaatgg gcgttacatc
    14521 aagaatttct tgcttaatcg agcaattctt gatggttacg gttctaagct catggttgga
    14581 cgtttcccaa ttgttgtgat tgatattcag attgatccct atttggccga tgtcaatgtt
    14641 caccccacaa aacaagaggt tcgtatttca aaagagcgtg aattaatggc tttaattagc
    14701 acggctattt cagagagtct taaggaacaa gatttgattc cagatgctct ggaaaactta
    14761 gccaaatcaa gcacacgaca tttctctaaa ccagagcaaa cacaacttcc tttacagtct
    14821 aggggacttt attatgatcc tcaaaagaat gacttttttg tcaaagagtc ggctgtctcg
    14881 gaaaaaatac ctgaaactga tttttattcc ggcgctgttg acaacagtgt aaaggttgaa
    14941 aaagtagagc tgttacccca ctcagaagaa gttataggac cttcttcggt taaacacgca
    15001 agtcgtcccc agaatacctt taccgagact gatcatccta atcttgactt aaaaaacaga
    15061 caaaagttat ctcaaatgct aacccgtttg gaaaatgaag ggcaatcagt gtttcccgaa
    15121 ttggattatt ttggtcagat gcacggaact tatctctttg ctcagggaaa agatggttta
    15181 tttataattg accaacacgc tgcccaggag cgggttaaat acgaatatta tcgtgataag
    15241 ataggtgagg ttgacagtag tttacagcaa ttgttggtgc cctatttgtt tgagttttct
    15301 ggttctgatt tcattaactt acaggagaaa atggcactct taaatgaagt tggtatcttc
    15361 ttagaagttt atgggcacaa tactttcatt ttgagggagc atcctatctg gatgaaagaa
    15421 gaagagattg catctggtgt ctatgaaatg tgtgacatgt tacttctaac caatgaggta
    15481 tctattaaaa cttaccgagc agagttagct attatgatga gttgtaaacg atctatcaag
    15541 gcaaatcata gcttggatga ttattcagca agaaatctgc tactgcaatt ggcccaatgt
    15601 caaaatcctt ataactgccc tcatggtaga cccgtattga ttaattttag taaggcagat
    15661 atggaaaaaa tgttccgtcg aattcaagaa aatcacacta gcctgcgaga gctaggaaaa
    15721 tattagagag gatgagatgc aagagttttt aaaccttcct aagcagattc agctgaggca
    15781 actggtacgc tttgtgacca ttaccttagg cagtagtatc tttcccttta tggccatgta
    15841 ttatacgact tactttggta cgttttggac aggcctctta atgatgatta ccagtttgat
    15901 gggatttgtt ggaactttat acggtgggca tctgtcagat gctcttggtc gcaaaaaagt
    15961 cattatgatt gggtcagtag gaacaacact aggctggttt ctgactattt tagctaattt
    16021 gcctaatgcg gctattcctt ggttaacctt tgcgggtatt ttattggtag agattgcttc
    16081 tagtttttat ggtcctgcct atgaagctat gttgattgat ttgactgatg agagtaatcg
    16141 tcgatttgtt tacaccatca attattggtt tatcaatatt gccgtcatgt ttggtgcagg
    16201 gctatctggg cttttttatg accatcattt tttagccttg ttagtagcct tattactcgt
    16261 caatgtactt tgttttggcg ttgcttacta ctgttttgat gaaactagac cagaaacaca
    16321 cgcttttgac catggtaaag gattactggc gagttttcag aactaccgtc aggtgtttca
    16381 ggatcgtgcc tttgtcttgt ttaccttagg tgccatcttt tctggtagta tctggatgca
    16441 gatggataac tatgtgccag tccatttgaa actgtatttt cagccaacgg ctgtgttagg
    16501 tttccaagta actagttcta aaatgttatc attaatggtt ttaactaata cattgctgat
    16561 tgtccttttc atgacagtag taaataaatt aacggaaaaa tggaaactat tacctcagct
    16621 tgtggttggt tctttactat ttactctagg gatgctcttg gcatttacct ttacgcagtt
    16681 ctatgctatt tggctatcag ttgttttgtt aacttttggg gaaatgataa atgttcctgc
    16741 tagtcaagtc ctacgtgctg atatgatgga tcattcccaa ataggatctt atacaggttt
    16801 tgtgtcaatg gcacaacccc taggtgctat tttggctagt ctactagtat ctgtcagcca
    16861 ttttacaggt cctttaggtg tgcaatgcct atttgtagtc attgctttgc tagggattta
    16921 ttttacggtt gtttctgcaa aaatgaaaaa ggtgtagtat gtacgattat attaaaggtc
    16981 aattgaccaa aattacggca aaatacattg tcgttgaaac aaatggacta ggctatatta
    17041 tcaatgtagc caatccttat agctttacag atagtgtcaa ccaactggta actatttacc
    17101 tgcatcaagt gattcgtgag gatgctcact tgttgtttgg gtttcatacg gaagacgaaa
    17161 aagatgtttt tctgaaatta atttctgtat ctggcattgg ctccacaaca gctcttgcta
    17221 ttgtggcagt tgatgataat gagggacttg tgaatgccat tgataacagt gacattaagt
    17281 acctaatgaa atttcctaaa attggtaaaa aaacagcgca gcaaatggtt cttgacttag
    17341 ctggcaaatt tgtggaggct ccacaagaga ctggtcatac caaagcgcgc agcaataaag
    17401 caggcaatac tcaactggac gaagcgattg aagccctcct tgccctcggt tataaggtag
    17461 cggaattgaa gaaaattcgt gccttctttg aaggaacctc tgaaacggcc gaacaataca
    17521 tcaaatcagc ccttaaacta ttaatgaaag gctaggtgtt tcacatgaaa cgttgctcat
    17581 gggttcctaa ggataaccag ctttactgtg attaccacga tttagaatgg ggtcaacccc
    17641 tacatgatga tagagatttt tttgaattac tctgccttga aagttaccag tcaggcttat
    17701 cctggctgac tgttttgaaa aaacgccaag ctttcagaac tgtttttcat cattacgaca
    17761 ttgcatcggt tgcagccttt acctcggagg aactggctga cgctttagag aatccatcca
    17821 tcattcgcca caagctaaag ctagcagcaa ctgtcaacaa tgctatcgca gtacagaaaa
    17881 ttcaagaaga gtttggtagt ttttcaactt atctctggaa ttttgttggg ggaaagccaa
    17941 ttaacaacct tgtcaatcaa gagaatcttg ttcctgctca aacagaatta tctattcgct
    18001 tagctaagga tttaaagaaa agaggattta aatttttagg gcctacaacg gtttattctt
    18061 ttatgcaagc atcgggtctg gtaaatgacc atgaagaggc ttgtgttttc aatagaatct
    18121 tctaattctt cgtgaattgg aagatttttt gataaaatga gatcagatta cgaatagata
    18181 agtaggtggg gaaatgaaag ctgaactgat tgcagtaggt accgaaattt tgactggtca
    18241 aattgtgaat accaatgctc aatttctgtc ggaaaaaatg gcagagctag gtattgatgt
    18301 ctattttcaa acggctgttg gggacaacga ggagcgttta ctttcagtga ttacaactgc
    18361 tagtcagcgt agtaacttgg taattttatg tggtggcctt ggtccaacga aagatgattt
    18421 aaccaaacaa actttagcaa agtaccttag gaaagacttg gtttatgatg agcaagcttg
    18481 tcagaaacta gatgactttt ttgctaagcg caagccttca tcacggacac caaataatga
    18541 gcgacaggca caagtgattg aagggtcaat ccctttgcca aataaaactg gtcttgcggt
    18601 tggtgggttc atcacagtcg atggtattag ttatgttgtc ttaccgggtc ctccaagtga
    18661 attgaagccg atggtaaatg aagaattggt accacttctg tcaaaacaat acagtacatt
    18721 gtattcaaag gtactacgct tttttggtat tggggaaagt cagttggtaa cagtcttgtc
    18781 agattttatt gagaatcaaa ctgatccaac cattgctcca tatgctaaga ctggcgaagt
    18841 gactcttcgc ttatcaacaa aaactgaaaa ccaagctctg gcagataaaa agttaggcca
    18901 gctagaagcg cagctactat cccgaaaaac tcttgaaggt caacccttag ctgatgtctt
    18961 ttatggctat ggggaggata attccttagc gcatgagaca tttgagctct tagtaaaata
    19021 tgataagaca attacagcag cagaaagtct aaccgcggga ttatttcagt caactttggc
    19081 gagttttcca ggagcttctc aagtattcaa tggaggcttt gtgacttata gcatggaaga
    19141 aaaagcgaaa atgctaggcc ttcctttaga ggagttgaaa tcgcatggcg ttgttagtgc
    19201 ttatacggcc gaggggatgg cggagcaagc aaggttattg actggtgctg atattggggt
    19261 aagtttaaca ggtgttgccg gaccagatat gttggaggaa cagcctgcag gtacagtttt
    19321 cattggtctt gccactcaaa ataaggtaga atcaataaag gttttgatta gcgggcgaag
    19381 tcgtttggat gtgcgctata tcgctacttt acatgccttt aatatggtcc gtaaaacttt
    19441 attaaaactt gagaatttgc tataatgtta tttagtagct atagtaggat atggtttacg
    19501 attatgtaga ttaatcctgc tgacgatggt ttgttaaaaa agaggagaaa gtattggcaa
    19561 aaaaattaaa aaagaatgaa gaaatcacta agaagtttgg tgacgaacgt cgcaaagccc
    19621 ttgatgatgc tttgaaaaat attgaaaaag attttggtaa gggcgcagtg atgcgattag
    19681 gagaacgtgc agagcaaaaa gttcaggtta tgagttcagg aagtctagct cttgatattg
    19741 cgcttggagc tggtggttat cctaaaggac gtatcatcga aatctatggt ccagagtctt
    19801 ccggtaaaac gactgtggct ttacatgctg tagcacaagc tcaaaaagaa ggtggaatcg
    19861 cagcctttat cgatgccgag catgcgcttg atccagctta tgctgctgcg cttggggtta
    19921 atattgatga actcctcttg tctcaaccag attctggaga acaaggactt gaaattgcag
    19981 gtaaattgat tgattctggt gcggttgatc tggttgttgt cgattcagta gcagctttag
    20041 tgccacgtgc tgaaattgat ggtgatattg gcgatagcca tgtcggattg caagcacgta
    20101 tgatgagtca ggccatgcgt aaattatcag cttctattaa taaaacaaaa actatcgcta
    20161 tctttattaa ccaattgcgt gaaaaagttg gtgtgatgtt tggaaatcct gaaacaacac
    20221 caggtggtcg agctttgaaa ttctatgctt ctgttcggct ggatgtgcgt ggaacaactc
    20281 aaattaaagg aactggtgac caaaaagata gcagcattgg taaggagacc aaaatcaagg
    20341 ttgttaaaaa caaggtcgct ccgccattta aggtagcaga agttgaaatc atgtatgggg
    20401 aaggtatttc tcgtacaggg gagcttgtga aaattgcttc tgatttggac attatccaaa
    20461 aagcaggtgc ttggttctct tataatggtg agaagattgg ccaaggttct gaaaatgcta
    20521 agcgttattt ggccgatcat ccacaattgt ttgatgaaat cgaccgtaaa gtacgtgtta
    20581 aatttggttt gcttgaagaa agcgaagaag aatctgctat ggcagtagca tcagaagaaa
    20641 ccgatgatct tgctttagat ttagataatg gtattgaaat tgaagattaa aaagagccct
    20701 tcagggcttt ttaaaatgta tttttaaagg ttagtagaac tactgttcat aggtgtgtgg
    20761 gtgaatagaa accatcattt aaaaagatgt gagagagcag aacttaggtt aactgatata
    20821 aaattaaaat aactaataat tcaagggaat acaggtgaaa aaccttattt tactaagata
    20881 atatctttaa aattaaaaaa ataggtccaa agacctatat ttatagataa gaaactgtgc
    20941 tacaataaag ctatcacgaa atagaaagtg agtcagcaac atgattaaaa tttacacgat
    21001 ttcaagttgt acgagctgca agaaagccaa aacttggcta aatgcccata agcttgctta
    21061 taaagaacag aacttaggaa aagaaccgct aactaaagaa gaaattttag caattttatc
    21121 aaaaaccgaa aatggagtgg agagcattgt ttcatctaaa aatcgttatg ccaaagctct
    21181 cgattgcgat attgaagaat taagtgttag tgaggttatt gatttgattc aagataaccc
    21241 gcgcatcctt aaaagtccca ttttgattga tgataaacgt ctgcaagtag gctacaaaga
    21301 agacgatatt cgtgcttttt tacctcgctc tattcgtaat attgaaaata ctgaagcacg
    21361 attacgtgct gcactctaaa agctcttgta gagctttttt ttaaatacct tcttcgccac
    21421 gccaaacgca tgaagaaact tttgttttca gaa
//
LOCUS       DAUNLR010000026        21354 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUNLR010000026 DAUNLR010000000
VERSION     DAUNLR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21354
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.026"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..578)
                     /locus_tag="VLL59_001050"
     CDS             complement(<1..578)
                     /locus_tag="VLL59_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509178.1"
                     /translation="MRNWKVTGNYPQWDGTGAVIDTQVIITDDRGAVIAEKIKKDLRT
                     ANDAEIIEAALEEFKKTAYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIEPAKKGEYQAYDVFTVVDESHEEQ
                     AGEGNLVFVHVNEAFEYDKQTLEELESEAKVTV"
     gene            complement(581..742)
                     /locus_tag="VLL59_001051"
     CDS             complement(581..742)
                     /locus_tag="VLL59_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509179.1"
                     /translation="MQEKLLGKIINDLTLKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            complement(756..2651)
                     /locus_tag="VLL59_001052"
     CDS             complement(756..2651)
                     /locus_tag="VLL59_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HER6509180.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFTADGDTKSVKIANNKCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGTGNLTGLFKDLKEISLELTDTKNSKLWSKIKL
                     NNQGMIEEYYNGTIKSEIIKTAEGTQQRISSETDKKLALINETVSGIRREYQDADRQL
                     SSSYQAGIEGLKATMANDKIGLQAEIQTTAQGLYQRYDNEIRKLSAKITTTSSGTTEA
                     YESKLDGLRAEFTHSNQGMRVELESKISGLQSTQQATARQISQEISNREGAVSRVQQG
                     LDSYQRRLQNAEGSYSSLQQTVSGLQSDVNSPNSKLNSRISQLASQIDQRVTRADVTS
                     IINQSGDSIKLAIQRAGGIDAKMSAKEIVSAINLNGYGVRISGERIALDGNTTVNGAF
                     GAKIGEFIKLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIEYAITSLLEGK
                     VIKARNGAMTIDLQSGQINHYTNESAMRRIDSSTASQFIKMTKSGFISEIGNMQAAMT
                     VIGSNSDGSENHENKTFGGIRIWNGKSSYQSTSFVELVGNRVAIYGNKNRSPWLFDST
                     TSGYAYLIPQNESGIKHAIGRADRKIDQIHVGDIYVQGERVAMMLKDLANRIGYIGTG
                     GWANRIG"
     gene            complement(2662..2991)
                     /locus_tag="VLL59_001053"
     CDS             complement(2662..2991)
                     /locus_tag="VLL59_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509181.1"
                     /translation="MRGHNLLKDLNNIIINNKTIDRIICNNTIVYQRSWDLLFDGLLT
                     SAGKKLDIYPFYKIVINNAFFVKTPTTKNNTIFLAGHKILALQDSHFCFFRALEKSFF
                     VKIYGKN"
     gene            complement(2978..4192)
                     /locus_tag="VLL59_001054"
     CDS             complement(2978..4192)
                     /locus_tag="VLL59_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509182.1"
                     /translation="MTSVETIPIKIVFDRKDASEWQSTNPVIDEGELVVELDTHKLKV
                     GDGKTSYNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTSIT
                     DITKDGETLTIKLSDDTQKIFNIPNGQKGDRGKGVESARIDESGHLKLKIEEESELDL
                     GNVKGESGPKGDSITITNHKRVSDGTQVSFSDGTQIVVPKGDTGDVNGINLEDYVKKS
                     ELKNVGSADVKAINDFLGLSQKVFTSSYSYTDSLLKSYAKPSYSASWYVNESTVSTKN
                     GDKVLITIHNTTTQADNYLEVAVTYVGANYVTATSTGRLLTTPGEVKVVTKKQAEKDY
                     AAKKHKHEISDIAGLNERLSGYLRQADIQSQLNNIGKLKDTQTGQYLEVKVVDKGQVP
                     SNTSGMIVFERS"
     gene            complement(4189..6336)
                     /locus_tag="VLL59_001055"
     CDS             complement(4189..6336)
                     /locus_tag="VLL59_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6509183.1"
                     /translation="MIPVLYEAKETKFRSFGLGEIADAYEIRVTRERNGNYSLYIKYP
                     LDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVNGASVGAESALEIWKENLVGDDTFDVKSDILTLGSFNWEADKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILRKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPFVR
                     YTPQPKPQEEASGKPHVGEHEQLEEQLVTLPEFILDGQYLSLYAQRRIQMVDLSSHFN
                     DDKNKKEPTVEEIRKLAQKYLKDNNVGAPKVSIEVDYIDLSQTLDYQDFRVMEEVELC
                     DIVPLYYPKFGITTESEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVSERINAL
                     ENNQKVITNNQKQFELNLPKYLNDINGNRVWYEKPDDNIEHKIGDYWFEKNGKYQHTW
                     IWDGNRWVKVLDTEDLNPNQRAFDEAMAEIEKAKKAQEEINQRTDKELEEFRATLKNL
                     ALPEEAIKKITETIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEILGNNGKTRYNKN
                     LLVGDPNRTKTYDEDYIEVEANDGGFKRGETYTISFSQTCELLQKVAVTLTQANNKGV
                     KLVLTPTKAKMESQTFDLTKDKQSIEVYPLSYTGVLTGDWYKSKSVEINASEAQELAL
                     EMAYKEIADAKGATIIGKQSDKPKIILDGRRDR"
     gene            complement(6333..7040)
                     /locus_tag="VLL59_001056"
     CDS             complement(6333..7040)
                     /locus_tag="VLL59_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6509184.1"
                     /translation="MRYIEFNGTKSDSLGLLLERERSIKSTSNDVNLIEVDGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGDTLQNPGNVQAKPILKIKGTGD
                     GVLTINGFETGLENVQRELVIDMERHLVYKDVLSAWDNIVRTKRHRMPLFDVGQNKIS
                     WTGSFTITAVPNWGVKV"
     gene            complement(7040..10963)
                     /locus_tag="VLL59_001057"
     CDS             complement(7040..10963)
                     /locus_tag="VLL59_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HER6509185.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAQVAELQNRLRALATETSVFTRFGKAAERIGGKMKSFGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYESAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIDLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTEKDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKQGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWKENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSILGKGIGVIGGTIQAIGKMSKGIGALSGWLRTFKAGA
                     VAASVGAEAATASMGSLTGAVALLSNPVTWGVLLGGAVVIGIGLIADSMYKAQKRTEE
                     WGTAVSATEATALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMIIAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHRGISQMASDMAQKLGISYDDAYRKMAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWQTMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQAIDSVKQTVPADVNATDKTAGDTQSAQSKIDNVKQKTPADVKAS
                     DKTGPDVASANRAVNSPKQNSPAVIRAQDNASGVAENVIWSLARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAVVNDQKGALYRELVTLPTGESFIPTGRNVILPLPRGSKVLK
                     ASRTKQLFPHYANGIGFDDTKIASLTTRLKSVQDKGTVVVNADPQLTELIKLLKDRDD
                     RNVTNNYTLNATNSSSSEDIFSQKNMRRLLRELAYYTKGEEGRLA"
     gene            complement(10976..11125)
                     /locus_tag="VLL59_001058"
     CDS             complement(10976..11125)
                     /locus_tag="VLL59_001058"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509186.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            complement(11173..11499)
                     /locus_tag="VLL59_001059"
     CDS             complement(11173..11499)
                     /locus_tag="VLL59_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509187.1"
                     /translation="MYEITLKKGGVDKEFKKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMTVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            complement(11552..12160)
                     /locus_tag="VLL59_001060"
     CDS             complement(11552..12160)
                     /locus_tag="VLL59_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HER6509188.1"
                     /translation="MGKVKFGLRDFYYGVLDGNDKVTKAESIKHLPGMKSAKLDITNE
                     LVTVPADDGPYVVLSGGISETKLEIELLDLTSDARKDFFGITVEKGVEKYNKNLTPND
                     IVCLFRTSDENGKAIWIALLKGKFNLPGMEAQTKEGAPDPKPDTTTGNFVARGPKEEV
                     LLVGREGNSGFNLNEFLKCVFAGCGDAEIKKIPIAEQASTVM"
     gene            complement(12176..12601)
                     /locus_tag="VLL59_001061"
     CDS             complement(12176..12601)
                     /locus_tag="VLL59_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509189.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGTFKNGFKQGIFTYDIPD
                     NPVNLRKVELAPFMRINTTLDGPFDYADDEILCNEQRITINFWCKTASEADQINKCID
                     NILKQGGFERYTANEKPRYKDRDIDLLMNVRKYRYFDFY"
     gene            complement(12598..12975)
                     /locus_tag="VLL59_001062"
     CDS             complement(12598..12975)
                     /locus_tag="VLL59_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HER6509190.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKSAVTEVAKEFEKALKANTPV
                     YEIETEERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAEKVKEGLGL"
     gene            complement(12972..13319)
                     /locus_tag="VLL59_001063"
     CDS             complement(12972..13319)
                     /locus_tag="VLL59_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HER6509191.1"
                     /translation="MITRKMNTRITIFSQSGGQNDDGEVVSAVRKDVYTCWAEVLKTQ
                     LRDFNYKSKFQNASDLPTNKDTKVFLIRYNPKLSIDNTMFVEFNNRIYKIDKIESDES
                     SKDITMISGVSMS"
     gene            complement(13316..13618)
                     /locus_tag="VLL59_001064"
     CDS             complement(13316..13618)
                     /locus_tag="VLL59_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HER6509192.1"
                     /translation="MAVSKELLESVKLYCKIDFDFEDDIIKEMIESAQEQICFAIEDG
                     STPERFKGHAKFALAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            complement(13763..14947)
                     /locus_tag="VLL59_001065"
     CDS             complement(13763..14947)
                     /locus_tag="VLL59_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HER6509193.1"
                     /translation="MFEEKIKEIKATIASLNQAIATKTAEVKNALESDDLETARSIKA
                     EVEKAKANLAEAENDLKLYESSAEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVNPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEIKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIATVLKEFEAKTVKNLDEIKKLLNVELD
                     PAYNVSFIVSQSFYQTMDTLKDKNGRYLLQDSITSVSGKVFLGKPVFVLADEVLGKDK
                     AFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVSKVDDKAGYYVTFTPDQL
                     PS"
     gene            complement(14972..15637)
                     /locus_tag="VLL59_001066"
     CDS             complement(14972..15637)
                     /locus_tag="VLL59_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HER6509194.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEATSAKSIINQLPEDSSDI
                     ILEVNSNGGLVTVGSEVYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFNLVCGNSDDLDKASNALKSSDKAIVNAYVAKTGLSEDEIMNLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNQMLPQAVIDDYYANRSKRKQEISNMLLEIEKEEIL
                     QGL"
     gene            complement(15615..16835)
                     /locus_tag="VLL59_001067"
     CDS             complement(15615..16835)
                     /locus_tag="VLL59_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HER6509195.1"
                     /translation="MSFFQPLGSSKVSYDDYISSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRNPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDTLTAKQVKCFAHDVVHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILTMKGAQLSGDARQR
                     ARQEFEKMREGSVGGSPLVFDSTMEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLNDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLIELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            complement(16869..17093)
                     /locus_tag="VLL59_001068"
     CDS             complement(16869..17093)
                     /locus_tag="VLL59_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509196.1"
                     /translation="MNKRIKKKRKLETAIVLLIKEVAELRSIVSANAKATNNELAAVK
                     SAILDNQVAIKSIGDEVGHIKQNYKRKWRK"
     gene            complement(17086..17256)
                     /locus_tag="VLL59_001069"
     CDS             complement(17086..17256)
                     /locus_tag="VLL59_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509197.1"
                     /translation="MIDFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIVL
                     AIYVDSVGGKRE"
     gene            complement(17253..19007)
                     /locus_tag="VLL59_001070"
     CDS             complement(17253..19007)
                     /locus_tag="VLL59_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HER6509198.1"
                     /translation="MTIEYDYSAISDIYKDDAFYYAKMVVDEQIKSSKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPEKAADPINFIEILPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDGEIV
                     DDGYFGYVAEQDNEEEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKTTWELARIDKPDTNKRRVWLGVDVGRVSDLFAITPVVM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEINGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KKGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLESF
                     DGSGYWTNEKIIGGESLF"
     gene            complement(19022..19489)
                     /locus_tag="VLL59_001071"
     CDS             complement(19022..19489)
                     /locus_tag="VLL59_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HER6509199.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQRTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            complement(19657..19998)
                     /locus_tag="VLL59_001072"
     CDS             complement(19657..19998)
                     /locus_tag="VLL59_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HER6509200.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDKQVKQFYN
                     SRIWRETSKQVLLQNDYICAMCGGEATMTDHIVSVKQDWNKRLDLNNLQASCKACNDS
                     KAIRERRKNNY"
     gene            20234..20419
                     /locus_tag="VLL59_001073"
     CDS             20234..20419
                     /locus_tag="VLL59_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HER6509201.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPMHNK
                     DLGKGLEDTILKQAGLK"
     gene            20471..20848
                     /locus_tag="VLL59_001074"
     CDS             20471..20848
                     /locus_tag="VLL59_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HER6509202.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGEDFQEAYEMAVEVLG
                     FALEDYTDYPKASAVSDLKEQYPDSDIALIGIDMVAYMKKYHSKKVRKNVTIPEWLND
                     AAEDKNLNFSQVLTEALELKLQA"
     gene            21164..>21354
                     /locus_tag="VLL59_001075"
     CDS             21164..>21354
                     /locus_tag="VLL59_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509203.1"
                     /translation="MKDKKVATNRRSIIFISVPKSSIITTNLLEPEVGINEKLAKNIA
                     VTIAENDRDADIISVKFFKL"
BASE COUNT         5649 a         4758 c         3658 g         7289 t
ORIGIN      
        1 actgttactt tggcttctga ctctagctcc tctaaggttt gtttgtcata ctcaaatgct
       61 tcattaacgt gtacaaagac taggttccct tcgcctgcct gctcttcgtg cgactcgtct
      121 actaccgtaa agacatcata ggcttgatac tcaccttttt tggctggctc gattagctca
      181 agcatgcctt tgtaaatatc aggctctact ttatcactag tggtcaatac gtggatggtt
      241 tgcaagttaa tcatcttttg tgtgcgctct gcggacactt tagctagtcc agcagctgtt
      301 tgagcagtct tggcagtctt agcagtttcc tgtgagattt tttcaaggtc gtctactttt
      361 tgcacggctt cgcccatagc gatttcgacg taagcagtct ttttaaactc ctctaaagca
      421 gcctcgataa tttctgcatc attagctgtt ctcaaatctt ttttgatctt ctctgcgatg
      481 actgcacccc tgtcatctgt aataattacc tgcgtatcaa tgactgctcc tgtaccgtcc
      541 cactgtgggt agtttcctgt tactttccaa tttctcatgt ttatttacct tcttccttcg
      601 gtgctgttgc ttcatccaat tgtgcgttta attcttccaa ttcgatttca tgctgtgctt
      661 ttaattgagc attttccagc gttaaattag cgactttaag tgttaaatcg ttaataattt
      721 ttcctaataa tttttcttgc attgtttctc ctaatttatc ctatgcggtt agcccagcca
      781 cctgtaccta tatagccaat cctattcgct aaatctttta acatcatagc gacacgttcg
      841 ccttgcacat agatatctcc aacgtggatt tggtctatct tacgatcagc tctccctatg
      901 gcatgcttta taccactttc attctgtgga atgaggtaag catatcctga cgttgttgag
      961 tcaaagagcc atggactacg atttttattt ccatagattg ctacacggtt accgactaat
     1021 tcaacaaaac ttgtcgattg ataagatgac ttcccgttcc aaattcttat gcctccgaag
     1081 gttttatttt catggttttc tgacccatcg ctattagagc ctataaccgt cattgcagct
     1141 tgcatgttac ctatctcaga tataaagcct gactttgtca tctttataaa ctgactagct
     1201 gtactgctat cgatacgtct catggctgac tcatttgtgt aatggttgat ttgaccgctt
     1261 tgcaagtcta ttgtcatcgc accattacga gccttaataa ctttaccctc aagcaaactt
     1321 gtgatcgcat actcaatcct tgctttaata aaattagcgt ctaaaccaac aatactgcta
     1381 gcgttgagat taatcacatt gattttgttt gcatcgattg tcccaccgat aatctggtcg
     1441 gcttttagct tgataaactc accaattttt gcgccaaaag ccccgttaac cgtggtattg
     1501 ccgtctaaag caatacgctc accagaaatt ctgacaccgt agccattgag gtttatggct
     1561 gagacaatct cttttgcgga catcttagca tcaatcccac cagctctctg tatggctaac
     1621 ttgatactgt ccccagactg gttaatgatg cttgtcacat cggctcttgt gactcgttgg
     1681 tcaatttgac tagctaattg gctaatccga gaattaagct tactgtttgg actattaaca
     1741 tcagactgta aaccactaac agtttgttgt aagctgctgt aactcccttc agcattttgt
     1801 aatcgccgct gataactgtc taggccctgt tgtacacgac tgacagcacc ttcacggtta
     1861 cttatctctt gtgagatttg cctggcagtt gcttgttgcg ttgattgcaa cccactgatt
     1921 tttgactcca gctctacgcg cataccttga ttactatgag taaactcagc tcgtaagcca
     1981 tcgagcttgc tttcataggc ctctgtagtg cctgacgagg tagtggttat tttagcggac
     2041 agcttgcgta tctcgttatc atacctttga tacaagcctt gagcggttgt ttgtatctca
     2101 gcttgtaaac cgattttatc attggccatt gtggctttta gcccctcaat accagcttgg
     2161 tagcttgacg atagctgtct atctgcatct tggtactcac gtctaatgcc tgagactgtc
     2221 tcgttgataa gcgcaagttt tttatcggtc tcgctactaa tacgttgctg cgtgccctct
     2281 gcggttttga taatctcaga ttttattgta ccgttgtaat actcttcaat catcccttga
     2341 ttattaagct tgatttttga ccaaagtttg gagtttttag tatctgttaa ctcgaggcta
     2401 atctctttga ggtctttaaa tagtccagtc agattacctg tcccctcgac aaccacgggc
     2461 gccacgtagt tagttggttt accccctcgc tcaatcatga gctggttaaa gcgagttgta
     2521 ccgatacatt tgttattggc tattttaacg ctttttgtgt caccatcagc cgtaaatgta
     2581 taataagcac gtccatctga gccgattgtt aaatttgact cgtctattaa aagtgttggg
     2641 tctctactca aatgttacct cctaattttt accgtaaatt ttgacaaaaa aacttttttc
     2701 taatgctcta aaaaaacaaa aatgactatc ttgtaatgct agtattttat gccctgctaa
     2761 aaaaatcgta ttgttttttg ttgtgggggt tttaacaaaa aatgcattat tgattacgat
     2821 tttataaaaa ggataaatat ccaatttttt cccagcgctt gtcagcaaac cgtcaaaaag
     2881 cagatcccac gaacgctgat agacaatcgt attattacaa ataatacgat caatcgtttt
     2941 gttattaata atgatattat ttaaatcttt taacaaatta tgacctctca aacacgatca
     3001 tgccactggt attgctaggc acctgtcctt tatcaaccac tttaacctca agatattgtc
     3061 cggtttgcgt gtcttttagc ttaccgatat tattaagctg tgactgtata tcagcttgtc
     3121 tgagatagcc agacaagcgc tcattaagac cagctatgtc actaatctca tgcttatgtt
     3181 ttttagcagc ataatctttt tccgcttgct tttttgtcac tactttgact tcaccaggag
     3241 tagtcagtaa gcgacctgtt gaggtagcag tcacgtagtt agcaccaaca taagtcaccg
     3301 ctacctccaa ataattgtct gcttgggtgg tagtgttatg tattgtaatc aatactttgt
     3361 caccattttt ggtagaaact gtagattcgt tgacatacca actcgccgaa tagctgggtt
     3421 ttgcataact ttttagtaag ctatctgtat aactatagct gcttgtaaac accttttgag
     3481 atagccctaa aaagtcatta atagctttaa catctgcaga accgacgttt ttaagttcag
     3541 attttttgac ataatcttcc agattgatgc cgttgacatc accagtatcc ccttttggga
     3601 caacaatttg tgtcccgtcg ctgaaagata cctgcgttcc atctgaaaca cgcttgtgat
     3661 ttgtgatagt aatactatca cctttaggtc ctgactcacc tttaacgttt ccaagatcta
     3721 actctgattc ctcttcaatt tttaatttta aatgaccgga ttcgtcaatc ctagcgctct
     3781 ctacgccctt acctctatcc cctttttggc cattggggat attaaagatt ttttgagtgt
     3841 cgtctgatag tttgatagtg agtgtctcac catctttggt gatgtcggtt atacttgtcc
     3901 ctttgtcccc tttttgacct ttgatgttgc caagcttagt ctctttgtcg ccaatccaca
     3961 cagacaagtc accattttcg gatagttgta cttttgttat ggattctcct tgcggacctt
     4021 catagtaagg caagtcattg tagcttgttt taccatctcc gacctttagc ttatgggtgt
     4081 ctagctcgac gactagttca ccttcgtcaa tgacagggtt agttgactgc cattctgaag
     4141 cgtcttttcg gtcaaagaca atttttattg gtattgtttc gactgatgtc atctgtccct
     4201 cctcccatct aaaataattt ttggtttatc ggactgtttg ccgataatag ttgcaccttt
     4261 ggcatctgca atctctttat aagccatctc aagagctaat tcctgcgcct ctgaggcgtt
     4321 tatctccaca gacttagatt tataccaatc acctgttaaa acgcctgtat agctcaaagg
     4381 ataaacctct atagactgtt tatctttagt gaggtcaaag gtctgcgact ccatttttgc
     4441 tttagttggt gtcagcacta acttaactcc cttgttgtta gcctgtgtca gcgtgacagc
     4501 cactttttgg agcagctcac aagtctgact aaagcttatc gtgtacgtct cgccacgctt
     4561 aaaaccaccg tcgttggctt ctacttctat gtaatcctca tcataggttt tggtgcggtt
     4621 agggtcgcca accagcaaat ttttgttgta gcgggtctta ccgttgttac ctaaaatttc
     4681 ggcgtttaga cgggacgtct cgctcgtttc actgactttg tttttgaggt catcaaagct
     4741 ttgtttaatc gatgggatgt catcaacttt gatagtctct gtgatttttt taatcgcttc
     4801 ctctggtaac gctaggtttt tgagggtggc tcggaattcc tctagctctt tgtcagtacg
     4861 ctggttaatt tcttcctgcg cttttttagc tttttcgatt tccgccatcg cctcatcaaa
     4921 agctcgttga ttggggttta aatcctctgt atctagtact ttaacccatc gattgccatc
     4981 ccaaatccat gtgtgctgat acttcccatt tttttcaaac cagtaatcac ctatcttgtg
     5041 ctcaatattg tcatctggtt tttcgtacca gacacggtta ccattgatgt cattgaggta
     5101 tttaggcaga ttgagttcaa actgtttttg gttgttagta ataacctttt gattattttc
     5161 caacgcattg atacgctctg agaccccgcc tgtcaaactc ttagatatgg attgaccaat
     5221 cgtaccaagt tttattgtgt ggttgctatc cgtatagaca tcatagacaa tctcaacgac
     5281 tttttcagac tcagtcgtga tgccaaattt tggataatag agtggtacga tgtcgcaaag
     5341 ctctacctcc tccataacac gaaagtcttg gtagtcaagt gtttgtgaca agtcaatata
     5401 atcaacctcg atactgactt taggtgcgcc tacgttatta tccttaaggt atttctgagc
     5461 cagctttcta atttcttcaa ctgttggctc ttttttattt ttgtcatcgt taaaatgact
     5521 tgataaatca accatttgga ttctgcgctg agcatataag ctgagatact gaccatctag
     5581 gataaactcg ggcagcgtca ccaactgttc ttcgagttgc tcatgctcgc ctacgtgagg
     5641 cttaccagag gcttcctctt gcggttttgg ttgtggcgtg tatctaacaa atggataaat
     5701 agaggtgtaa ttgccatcaa gcaagcgctc ctcctctacg ctgacgatat tacggccata
     5761 ctccaatacc gtgggagctt tacgccccat ttgcttgcgt aagatgattg tacggttgtc
     5821 aaactcgtac tcaccaccgt aaacatctag gatagagcca gcgacacctc ctagagcacc
     5881 acgggcattg ccgattttat cagcttccca gttaaaactc ccaagcgtta agatgtcgct
     5941 tttaacgtca aaagtatcat caccaacaag gttttctttc cagatttcta aagctgattc
     6001 ggctcctacg ctcgcaccgt ttacaaacgg ttttaaagca atatcctgtg tgcgcataga
     6061 aatatgacgc gcaaaaatct caatgtggtc tttactattg cgcagcactc gattaatctc
     6121 aaaagtctgc catttggttc ttcgcccagc gtcagactta atcttcattt cctctttaaa
     6181 aactgaggca aatactccgt ctaaagggta tttgatatat agcgagtaat tgccattacg
     6241 ctctctggta actctgatct cgtaagcgtc cgcaatctct ccaagaccaa aactcctaaa
     6301 cttggtttcc ttagcctcgt ataaaactgg tatcatactt taacccccca gtttggcact
     6361 gcggtaattg taaagctacc agtccacgag attttgtttt gaccaacatc aaaaagtggc
     6421 atgcggtgac gctttgtccg aacgatatta tcccaagcag ataggacgtc tttatagaca
     6481 aggtgccttt ccatgtctat gacgagttcc ctttgcacat tttcaagtcc tgtctcaaaa
     6541 ccgttaatgg ttaaaacacc atcgcctgtg cctttgattt ttaagatagg tttagcctgt
     6601 acattgccgg gattttgtag ggtatcgcca ttaacaagag gcacctcttg cttacctgtt
     6661 tttaaatatt tgatagggtg gattaagaaa ttaaccttta atctaccaaa ttgcttaagt
     6721 atctcgtcta tctcaaaaag attgacaaca ctagcccgat agatatagtc cttgtcccaa
     6781 gacaaagcta agtcatgcca acctttgacg tgcaaccact cgcttatttt ttgctgattg
     6841 acagccacgt caccaaccag cgaaaaagga aagtcttgct caaccgcttt taagcgttcg
     6901 ttgtctttaa taagtacacc gtcacgacca tcgacttcta ttaaattgac atcgttactc
     6961 gttgacttaa tagaccgctc gcgttctagc aacaaaccta gactatcgct tttagtgccg
     7021 ttaaactcaa tgtatctcac taagctaacc tcccttcttc accttttgtg tagtaagcta
     7081 attctctgag tagccgtctc atgttttttt gactaaaaat atcttctgaa ctactgctat
     7141 tagtagcgtt tagtgtatag ttgtttgtga catttctgtc atctctgtct ttaagcagct
     7201 taatcaactc ggtaagttgt ggatcagcgt taacgactac agttccttta tcttgcacag
     7261 atttaagacg agttgttaag ctagcgattt ttgtgtcatc aaaacctatt ccgtttgcat
     7321 agtgcgggaa taactgtttt gtgcggctgg cctttaaaac ttttgaccct ctcggtagag
     7381 ggaggataac gtttcgacca gttgggataa atgattctcc agtcggtaag gtaactaact
     7441 ctctatatag cgcccctttt tggtcattga ccacagctaa cccgccaggg tggaaatcag
     7501 tccctttttc gtgtccgaaa atcttacgga caaacgttgt aatggttgtt gtaacacttc
     7561 ttgggattct agccaatgac catattacgt tttctgcaac gccgcttgcg ttatcttgtg
     7621 ctcttataac agctggacta ttttgtttag gactattgac tgccctattg gcacttgcaa
     7681 catctggtcc agtcttatcc gatgccttca catcggctgg cgttttctgc ttgacattat
     7741 caatcttact ttgcgctgac tgagtatcgc cagctgtttt gtccgtagca tttacatcgg
     7801 ctggtactgt ttgtttaacg ctgtcaatag cttgttgtgc tgacatagtg ggttcttgtg
     7861 ttaagttttt agctagcaaa accttttctt ctggtgtcaa cgcttgccat tgtgctagta
     7921 attctttgct atcaaagatt tcaatcatcg cttgttgacc atcaacaacc aactttttct
     7981 gttctaaagt catggtttgc cattggccac cagctactag catttcagca agagcggctc
     8041 tacctgttgg ttcaacatca gcattcttaa ccatgatttc aaagctattc caaccttctg
     8101 ccgttgataa caattcgttt aaactttgtt gtggattatc actcgtaaac aaactgtccc
     8161 attgagcatt tgctgctgct acctctgcag tagcattagc ggtattacgt gataaaactt
     8221 tcaacgtttc accggatttt tcggtatagt aagccatttt gcgataagcg tcatcatagc
     8281 taatgccaag cttctgagcc atatctgacg ccatttgact tatgccgcgg tggatttcct
     8341 cttgactttt accagattct tttaaccgtt ggactcgctc cctctggata gcaagatact
     8401 gatcattcaa agctttggtt tttaggttgt gctgcatatt aagttctgta agtctattca
     8461 aaacttcctg tctagcagcc aactcttcag cactcaattt actagtgtcg ctgccaaatt
     8521 gcttcaaaat ctcttttaac tctgcttttt ttgttttata tgcagagttt tctttatcaa
     8581 gcatcttgac ggtattttca gatacttttt ccaactgcct tgcatttagc gcatctaact
     8641 cgttattcaa agctgctgtt aaagctttct tttctgatgc agaaaacttc attaaatcaa
     8701 gttgagcaat aatcatttct ctctgatttc gcaaaacaag ttctttctca gcgcttgaca
     8761 actggctcat gtcaccattg tgcttctcca tgattgcttt aatctgggtg ttcatgcttt
     8821 taacattgtt aaccactgat tcagttttgg atttcaaagc atttatggtt tcttctgaca
     8881 atcctaattt tttagctaag tttatattct tatctaattt tgattgagct aacttttcaa
     8941 tacttccgac caaatcatcg aaagcttcag tcactttctt aacgctacct gcgcctgcct
     9001 cgaacatttg caaagaagtg ttagtttcgt caactttttt cttaaagtta cttagtgcag
     9061 ttgcttctgt cgcggaaaca gcggttcccc actcttccgt gcgtttttgg gctttataca
     9121 tgctatcagc aattaaacca ataccaataa caactgcgcc acctagcaaa acaccccacg
     9181 ttaccgggtt gcttaataag gcaaccgcgc cagtcaaact gcccatagaa gctgtggcag
     9241 cttcagctcc aacacttgct gctactgcac cggctttaaa cgtgcgtagc caaccagata
     9301 aagcaccaat ccctttgctc atcttgccga tagcttgaat ggttccgccg ataacaccaa
     9361 tacccttacc caaaatagat aaagccggcc cagcggcggc tgcaataagt ccccacttga
     9421 taatttgctg ttgttgctct ttgtcgagcg agttaaattg tttagctaag tcagccgcca
     9481 tttggatgat tggcttccct gcttcgagcc cgtttctcag agcgtcaacc aaaggaccac
     9541 caaattctat ggctacatca ttgacttcgt ttttaagcat tttcagctta gactctgttg
     9601 tctcgtaacg tttgttagct tcgtcagtca acgccgtgtt ttctttccaa gccttattgg
     9661 aaattccaag tgccttgcct aatgtttcag atgctaaacc taatgatttc aacatgttag
     9721 actggcgaat accgcttaat cctaactcat caagtacttt tgtggcactt tcgccttgtt
     9781 tatcaagttg accaagccct ttaataaact cttgcaatgc gacaattggc ttttctttcc
     9841 acgctctagc aaaatcggct gaggacatgt tagctatctg agcaaattta tttaaattat
     9901 cgcctccaga tgcgactgca cgttcaatag ctgataatga ttgagtcatt gctgtaccac
     9961 cagcctccgc ctctatacca acgcttgaca ttgctgtagc taaagctaac atctcctgat
    10021 tagttaatcc cgcaagctta ccagatgctg ctatacgatt ggtcattgca acaatgtctt
    10081 tttcagttgt cgcaaagtta ttccctaacg caacgacagc acttccaaaa cgcgaatact
    10141 cagatgatgc tagacctgta atatttgcaa ttttagcaat agacgtcgcc gcttcttctg
    10201 cggataaatt ggtagattct cctaaatcaa tcattgtacg agagaaacta agaatatctc
    10261 ctgtcttaac tcctaattga cctgctgctt ctgcaacgtg agcgatttca acagcactgg
    10321 ctggcaactc tttggccatt tgtctaatgc cttgcgacaa cttagcatag gataccgtcg
    10381 ccgtttcatc cacggttttc ttgacaccgg caaaagcaga ttcataatcg acagccgctt
    10441 taatagcata accagctcct gcaacaatcg gagctgtaac tcctcttgta aatgcagcac
    10501 ctacaccggc gacagaatcg ccgaatgact tcatcttccc gccaattctt tcagcagctt
    10561 taccaaatct tgtaaagacg ctagtttcag tggctaaagc tcgtaatctg ttttgcaatt
    10621 ccgccacttg cgctgctgtt tctagcatgg ctgatttagc gccaattaat ttttgttttt
    10681 gctcagcagt agcgttatta acatcaccta tctctttttt taggtcgcta tatttttgtg
    10741 actgagtttt tagtaattct tggtaacctt ttaatgcact acctgtttca gcatagaccg
    10801 ctttaagacc tttaatccgc ccgccatgcc cttgaaagct cttttcaact gcttttaaag
    10861 agttatctaa gcctttcatg taggttttta ggtttcttgt gtttgacata aagggtgata
    10921 tgtctaatgt agctgttgct actaaatcac ctatattccc catttagtct cctttctagc
    10981 cgaaaaggaa tgggaatgcc ttatccaagg tcgtttcaat cacttcttct ttttcgacag
    11041 tttcaatttc tagtgcttgt accatcaatt cgatgtctga taagcgcatt tttttaatat
    11101 ctaaaatggt ataaccgttt ttcaaaaggc tctgtatcca caagagtaag ttttctttag
    11161 cctcttgtgg ggttattgtt cctttttttc gctttcgtct tcctcctgct ctcctccgag
    11221 tgctgcaatg tacaggtcat taagtgtatt taaaacggtc atatcagatt gctttaaatc
    11281 atcaacggta aactgacctg cgtacatatc aacaaacatt tgcaagtaag attcgttaag
    11341 ttttctatgc gctttagaat ctaaacgtct tttctcatcg ctaaacacag cgctttgtct
    11401 aacttgatgc tcaacagcca acaaattatc ttcgacattg ataaagtctt ttttaaattc
    11461 cttatcaaca ccgccttttt ttaaggtaat ttcgtacata tctactcctt gtcaaaaata
    11521 aaaggtcgca gcttaaatgc gaccttaaaa attacataac cgtacttgct tgttccgcaa
    11581 ttggtatttt tttaatttct gcatcaccgc agccggcaaa tacacatttt aaaaattcat
    11641 tcaaattaaa accgctatta ccctcgcgcc cgaccaaaag cacttcctct tttggtccgc
    11701 gggcaacaaa gttacccgtt gtagtatctg gtttcggatc aggtgcgcct tcttttgttt
    11761 gtgcctccat tcccggaaga ttaaatttcc ctttaagcaa cgcaatccaa atcgccttac
    11821 cgttttcatc gctagtccta aataaacaaa caatgtcatt tggcgttagg tttttgttgt
    11881 acttctcaac acctttttct actgtgattc caaagaaatc tttgcgtgca tctgatgtta
    11941 aatctaacaa ctcgatttca agttttgtct cgctgattcc acctgataat acaacgtaag
    12001 gtccatcgtc tgctggcaca gtgaccaatt cattggtaat atcaagtttt gcggatttca
    12061 ttcccggcaa atgctttata ctctctgctt ttgtaacctt gtcatttccg tctagtactc
    12121 catagtaaaa atcacgtagt ccaaatttta cttttcccat tttttcctct ttcttttaat
    12181 aaaaatcaaa atagcggtat ttccttacat tcatgagtaa gtcaatatct ctatctttat
    12241 atcttggttt ttcattcgcg gtatatcttt caaaaccgcc ttgttttaaa atgttatcta
    12301 tacatttgtt aatttggtca gcttctgaag ctgttttgca ccaaaaatta atagttatac
    12361 gttgctcatt gcaaagtatc tcgtcatcag cataatcaaa aggaccatct aacgttgtgt
    12421 taattcgcat aaatggtgcc aattctactt ttcgtaagtt aacaggatta tccgggatat
    12481 cataagtaaa aatcccttgt ttaaatccat ttttaaaagt accgcctctg agcctatcca
    12541 acagctcatt tagcgtctta tcgttactta acaatttata agctgctgtt tcagcaatca
    12601 aagtcctagt ccctccttca ctttttcagc gtaaatctgc ttagcttttg gtgtcatctg
    12661 attgattgtt ttttccttaa agtcctgacc gcgttgataa atcgtcccat cgttaggata
    12721 gtgagcacgc caaccagttg ctttaccata accgatttct tttgaaacaa taccgacatt
    12781 agctccttta aaaccactga taacagtatc ttcttgcagt ctttcttctg tttcaatctc
    12841 ataaacagga gtatttgctt taagtgcttt ttcaaactcc ttagcaactt cggttactgc
    12901 tgatttcgct gttttaggag cttttacttc aagctttgtg agattagcta aaatttcatc
    12961 caaacctttt gtcatgacat gcttactcca ctaatcatag taatatcttt gctagattcg
    13021 tcagattcga ttttgtctat cttatagata cgattgttaa attcaacaaa catcgtgtta
    13081 tcgatagata acttaggatt atacctaatc aaaaagacct ttgtatcctt atttgttggc
    13141 aaatcgctag cgttttgaaa ctttgatttg taattaaagt ctcttaattg agttttcagc
    13201 acttctgccc aacatgtata gacgtctttt ctgacagcag atacaacttc gccatcgtca
    13261 ttctgaccac ccgactgact gaaaatcgtt atccttgtgt tcattttgcg tgtaatcatg
    13321 aatcatcacc ccgcaatcgt aattgatgga tgatatttaa aacgccattt gccaacggat
    13381 agcgaaaact atccgcagac aaaccgcgat ggtcgtactc ctccttgact tgctttttga
    13441 cagctaaagc aaatttagcg tgacctttga acctttcagg agtagaaccg tcttctattg
    13501 caaaacagat ttgttcttga gcagattcaa tcatttcttt gatgatgtcg tcttcaaaat
    13561 caaagtcaat tttacaatag agttttacac tctctaataa ctctttcgat acagccatag
    13621 ctatacctct tcaacgcctg caagttttga taaatctgat ttcaaggtct taccactaaa
    13681 atcaattccc ttgcttgtta aatagcgctt aatctcctcg acagtgcttt tactagttgg
    13741 tttcgccact tcttcagtgg ccttatgagg gcaattggtc tggcgtgaat gtcacatagt
    13801 agccagcttt gtcatcaacc ttagaaacgc caaagcgaag tacagcttgc aagtattgac
    13861 cgtaaatttc gttatctgcc cagcgaagcc caaggtcttt gcggtcggca aataatacac
    13921 cacgtttgaa atctccgaca aatgctttat ctttacctaa aacttcatca gctagtacaa
    13981 aaacaggttt tccaaggaat actttcccag aaacagaagt gattgaatct tgaagtaggt
    14041 aacgaccatt cttatctttt agtgtatcca ttgtttgata aaagctttga gatacaataa
    14101 atgaaacatt gtaagctgga tctaattcaa cattgagaag cttcttgatt tcatccaagt
    14161 tttttactgt cttagcttcg aattccttga gaactgttgc gatagcgtcg tttgttgtat
    14221 taactttcat ttgaccgatg gtctcagcaa caattccaac taaatcaaca tctgcatcgt
    14281 caattgactc ttgagacaac gggatagctc cacggtaagt tttaatttcc cattcgacgt
    14341 ttttgaattg tggttttcct agttttggat ttttttctaa ttcttcaacg ctaaccattt
    14401 tttcagtcgc acgttgcaat actggccatt ttcctgatgc ttttttagct gggtggatgc
    14461 tagtgaattg tttcaaatca acaactgtct taacttcacg agctggtgtg taaagaattt
    14521 cttcactaga aacaggtttc acatctgttt tcttaacacc gtccgtttta ggatttacag
    14581 gagtcgtttg gttaagtggg ataagaacct cgtctttccc ttcgaaacgc aaagcttcgt
    14641 tagttactgt tccttttgaa cggataaact cattaacgct ttcgcggtat gttttagttt
    14701 cttgtggcac ttcttttcct ccagtatttt ctgcaccgcc tttttcggcg cttgattcat
    14761 ataactttaa gtcgttttct gcttctgcta ggtttgcttt agctttttca acttctgctt
    14821 taattgagcg agcagtttca aggtcatctg attccaaagc attttttact tcggctgttt
    14881 tagtagcaat cgcttggttt aaactagcga tagtcgcttt aatttctttg attttttctt
    14941 cgaacataaa ttcctccaat aaaaaaagag cttatagccc ttgtaaaatt tcttcttttt
    15001 caatttctag caacatgttg ctaatctctt gcttgcgctt acttctgttt gcgtaatagt
    15061 cgtcaataac agcttgtggc aacatttggt tatcgatact cgccaccgct tcaaaagaca
    15121 tcacttcatc agcaaaacct ttttcaacag cgtcttgagc agacataaac gtttcattcc
    15181 gcattaaatt catgatttca tcttccgata accctgtctt tgcgacatag gcattcacga
    15241 tagctttatc acttgatttt aaggcgttag aagctttgtc taggtcatcg ctattaccac
    15301 acaccaaatt aaacaaagcc ttgtgtacca tcatctgtgc tgttggactc atgacaactt
    15361 tatctgctcc cataactgca acggatgctg cacttgcagc catgccagta atttctgcag
    15421 ttacttttcc tttgtaattt cgcaaagcgg tatagacttc actccctact gtaacaagac
    15481 caccgtttga attaacttcc aaaataatat cactgctatc ttctggcaat tggttaataa
    15541 tgcttttggc actagtcgct tccattccat agtagtcata aacttcttgc gaattatttg
    15601 caataagtgg gcctttaaga tttatcctct ttggcattta cctcacctcc tttccctttg
    15661 ataccaacct tgtcctgata ttcttctttt ttatccaaaa agacatagtt tagactcgat
    15721 tggtacctat ccatattagg atctgtagat ttctgcttac ctaactcaat aaggccttgg
    15781 ttaggtgtca gtatttgatt gttaaccaat ttgacaatct catcaacatt acggcctgta
    15841 acgctacgtg tatcaaattc aatacgatag agacgtctat ctttatcatt taacgtttta
    15901 agacctaatt cgcttgtaat cgcgtcaaaa taaaaaggca agtcgtttgt gacatagtcc
    15961 tccatcagtt gagctacgga ttgattaggg ctattaacac caagcttgta gctgggaacc
    16021 cgcaaagctt ttgcgatttg cgccgttgaa aaattgttac tagtgattaa ctgcaatacg
    16081 ttagtatcaa tttcaagcgg cgtgtattcc atggtactat caaacaccaa tggactgcca
    16141 ccgaccgaac cctcgcgcat tttctcaaac tcttgacgtg ctcgctgccg tgcgtctccg
    16201 cttaattgag cacctttcat agttaagata ccgctagaaa atccatcttt aaagaattta
    16261 attaaggtat tgataccacc tgtttgcaaa tcaatctcat ctcctaaaga cagtagcgga
    16321 gacctgccaa ggattgtgtc gtggctaaaa aacttccagt gtacaacatc atgagcaaag
    16381 catttgacct gtttcgctgt taaagtatca gtaaacgtat aaactatttc gtgattatct
    16441 gtttcctcaa cagtcgtttc tgacggcctg taaaattgga attgcaaagc ttgattagtc
    16501 tttggatttc tcaaaatacg cgaaaatgaa ttaccagtca aaatggcatt tactgccata
    16561 gcaaatttcc atgtcctggc gctcgcattt tttgtagatt taacatttaa aagataatta
    16621 atatcctcat cgtggataat atctccatta acgtcctttt taacaagcgg aaatctagca
    16681 atatccccag ctataataga cgtcgctgtt aaaatatcgc tattcttcaa agccgatact
    16741 cctaagtatt tttgggagac atcaccagct aaaacagatg atatatagtc atcataggac
    16801 acctttgaac tgcccaaagg ttgaaaaaaa ctcatcgatt tctcacctcc tttctaaacc
    16861 attaacatct atttccgcca cttgcgctta taattttgct tgatgtgacc aacctcatca
    16921 ccaattgact tgatggctac ttgattgtct agtatcgctg atttaactgc tgcaagctcg
    16981 ttatttgtag ctttggcatt tgctgacacg atggatcgta attcggcgac ttctttaatt
    17041 agcaacacaa tagctgtttc caattttcgt tttttcttaa tgcgtttatt cacgttttcc
    17101 tcctacgcta tctacataga tagctaaaac aattaaaata agaccactgg caataaaacc
    17161 gactttatca ccaaacaaaa acaacccata catcaataaa cctagtccag ctaacaagat
    17221 taatgtgtgt atgtttttta aaataaaatc aatcaaaaca gcgattctcc tcctattatt
    17281 ttttcatttg tccagtagcc agaaccatcg aacgattcta agtaacaaac agcgtagcca
    17341 tcaagagcag catcaagcgg gtcaatctta ttgctattct tattcttatc aatcctcata
    17401 ccattattat cagttttaat ataagcattg ttaacagcca tggttagcaa agggttacca
    17461 gagtgcttta ttttgccttt tttgaggtcg tcacgaaatt gttttgtcgg catgttcaaa
    17521 accattgtcg tctgcgaaac ctcaatcaga ggccactctg gatgcctttt ttcaatcatt
    17581 gtaagtaatg ttccaaattg ataagggtca aaacaaattc cattaatttc ccagtcgttt
    17641 gagtagacca tctcttcaat tttttcgagt acacgttcat catcaatgac accactttct
    17701 agggtggtta tctcgcaata accttggcgt tcaagattgc tataagatac gccatcccgc
    17761 ttttctttag cagttaaacc atatttggta gccacaaaag aaaagctgtc gatataccaa
    17821 aaatcatcca tcataacaac tggtgtgata gcaaataagt cgctaacacg accaacgtca
    17881 acacctaacc aaactctccg cttattagta tctggcttat caatccgagc aagttcccaa
    17941 gtcgttttat caatgtaaga ttcctcgcta gactgacgcc acatgttaaa gtttttgatt
    18001 aatactttat tgatttcacc agtttcaagg gacactctac ggcgcgttct caggtaatcc
    18061 attagcttat catgtaaagc ttcaacctca aggattggat ttgattttat ccagtttgat
    18121 tcgtctttaa tttcctcttc gttgtcctgt tctgcgacat aaccaaaata gccatcatct
    18181 acaatttctc cgtctagtat tttagtgatg tatggatact caattgtgtg catagggaca
    18241 ttcaaatcca tccctgccgt cgaaataatc aagataaacg ggttatcaag ctgaccttga
    18301 ccagattcta aaagttctaa catttcattc gtcttcgatg ctgcaaattc atccaaaacg
    18361 ccaacataag gctcaaatcc atctacagcc ccagtatctc gactaagtgc tctgatatat
    18421 gattcgtcat gtaagttttt aagctcatca cggacaattt ttgtagcctt tctgacatca
    18481 gcgtccttcg ctctgagaga tgataactgc ttctttgcca tatcccaagc gattttagcc
    18541 tgcgttctat catttgcagt acaaaacaat tgtctgctca tagatgggtt atggccaaac
    18601 aaaaattcat aaagcaagat accagctatc agaattgttt tgccgttttt acgagcaaca
    18661 gaaatcatag cttttctaaa acgtctcaag gaatgatctg ttttctttcg ccatccatat
    18721 aaattcccaa taataaactt ctggaacatc gccaacgggt aaggcttccc cgtctttaca
    18781 tctggcaaaa tctcaatgaa gttaatcggg tcagctgctt tttctggtaa atagataaat
    18841 ttaaaattat catcatctat ttttttaagg tcattcaaat gtctcaagca cgccttaaaa
    18901 acttttttac ttgattttat ctgttcatca acgaccattt ttgcataata aaaagcgtca
    18961 tctttataga tgtcgctgat tgctgaataa tcgtattcta ttgtcatgat cccctttctt
    19021 tttatcctcc aaatttatca aatatactct taggcttttc ctcttcctta ggaataaaca
    19081 tcttcatacg actgtccacc gtcaagccaa gctgacttgc gctacttcta atattcgctg
    19141 tggctttttc tagtgttaaa ataagcggac taggaataat gcctttgtct ggatcattcg
    19201 taaaataacc aacctcatct agttttctac ttgtttcttt gtagatagca taccatgtgc
    19261 aatataactc taatagccct ctatcgagat ttcttagggg taggttttgg aggtcttcta
    19321 tgattctcct atactcgtac ttagctacat tattaaagtg ttcaggaggt gtcctttgca
    19381 actttttaag accgtcagac gccttatttt gcgcggtttc tcgcactatt ttttcttctt
    19441 tcgtaagatg cttttttgtc gtttcgacta gctttaaatt tcttcccata agacctcctt
    19501 tacacgaact ttacagtttt aaaaatttca aaaagggaat tttttgcacg gaaaagggcg
    19561 cgttcttaag tttccgaaca atatagcccc gcttaaaaat gaagggggta ttttccgaat
    19621 attaacgtac tgttgttaat ttttacaccc gtttttctag taattgtttt tacgtctttc
    19681 ccttatcgct ttgctatcat tacatgcttt acagcttgct tgcaagttat tcaaatctaa
    19741 tcttttgttc caatcttgtt tgactgatac aatgtggtca gtcatagtcg cttcgccacc
    19801 acacatagca cagatataat cgttctgaag taatacttgc ttacttgtct ctctccatat
    19861 tcttgagtta taaaactgtt tgacttgttt atcgtacttc cagcgattac gattatagtc
    19921 acgatactct gctgatctgt catcgtagtc aactgttgta cgtctaccac ctgcgatagt
    19981 taacttctgt ggcctcatac cctgacctca ccagttagcc tattaatata atgaactaat
    20041 gttgtgtatg gaatagtgta gccgttatca acgtatatat tacttacttc tttttcccat
    20101 tgtggtttac tatacggata cttatttggt ctcatttgtt atctcctaat ttttgcgtat
    20161 tttatgcgta ttttgcattg acatctacat tgtttatgtg tataatataa gtatagaaag
    20221 tgaggtaagc aatatgccaa tgaccccaaa gcagatgata aaactgctaa aaaagaatgg
    20281 gttctacgaa gtcagtcaaa acggaagtca caaaaaattc cgagacaata acggacatca
    20341 aaccattgtt ccaatgcaca ataaagacct cggaaaaggt cttgaagata ccattctaaa
    20401 gcaggcgggt ttaaaataat ccgcttgcca gatggtgtgc ttatctcaca gtaatcaaag
    20461 gaggatcatt atgttaattt atccagctac atttacacaa gacacagact atatcatggt
    20521 tacatttcca gatgtacctg aagcaattac tcaaggtgaa gactttcaag aggcttatga
    20581 aatggctgtc gaagtcttag gctttgcgct tgaagactat actgattatc caaaggctag
    20641 cgccgtttct gatttaaaag aacagtatcc tgattccgac attgctttaa ttggcatcga
    20701 tatggttgcc tatatgaaaa aatatcactc caaaaaagtc cgcaaaaacg tgactatccc
    20761 tgaatggtta aacgacgcag cagaagataa aaacctcaac ttttctcaag ttcttactga
    20821 agcgcttgaa ttaaaattac aagcataaga gccactgttg tggttctttt ttacataata
    20881 aaaaaccacg tcgtggacct atcgaaacat tgtaatttca acgtttgtaa ctaataagta
    20941 accatgtcgt ggaccataac aaaaaagtca ccacaatgtg atgacctatt tatttttgaa
    21001 attattataa gtttcaacta acaaaattaa tgttcttagc acaaagaacg aacttaggaa
    21061 catcattact gttgagctca accaacttga aactactaaa attgaaatta aatcagtatc
    21121 agtcttacta aagaatagag aaatgaaaga taataaagaa ctaatgaaag ataaaaaagt
    21181 agcaactaat aggcggtcca ttatttttat ctctgtccct aaatcttcca tcatcactac
    21241 taatttatta gaaccggaag ttggtatcaa tgaaaaacta gcaaagaata ttgcggttac
    21301 aattgctgaa aatgatagag atgccgacat tatatcagta aaatttttta aact
//
LOCUS       DAUNLR010000027        20711 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUNLR010000027 DAUNLR010000000
VERSION     DAUNLR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20711
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.027"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            131..1114
                     /gene="guaC"
                     /locus_tag="VLL59_001076"
     CDS             131..1114
                     /gene="guaC"
                     /locus_tag="VLL59_001076"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HER6509204.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      1237..1332
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            1419..2000
                     /locus_tag="VLL59_001077"
     CDS             1419..2000
                     /locus_tag="VLL59_001077"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HER6509205.1"
                     /translation="MQLLEERTLTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            2000..3283
                     /locus_tag="VLL59_001078"
     CDS             2000..3283
                     /locus_tag="VLL59_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HER6509206.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVVGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIISAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(3347..4285)
                     /locus_tag="VLL59_001079"
     CDS             complement(3347..4285)
                     /locus_tag="VLL59_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HER6509207.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPLSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETNMLSLTIMAPSSFYCDIWATRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(4338..4523)
                     /locus_tag="VLL59_001080"
     CDS             complement(4338..4523)
                     /locus_tag="VLL59_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HER6509208.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            4661..5230
                     /locus_tag="VLL59_001081"
     CDS             4661..5230
                     /locus_tag="VLL59_001081"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HER6509209.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            5265..6344
                     /gene="prfA"
                     /locus_tag="VLL59_001082"
     CDS             5265..6344
                     /gene="prfA"
                     /locus_tag="VLL59_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HER6509210.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            6344..7183
                     /gene="prmC"
                     /locus_tag="VLL59_001083"
     CDS             6344..7183
                     /gene="prmC"
                     /locus_tag="VLL59_001083"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HER6509211.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            7167..7757
                     /locus_tag="VLL59_001084"
     CDS             7167..7757
                     /locus_tag="VLL59_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HER6509212.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITTALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            7775..8239
                     /locus_tag="VLL59_001085"
     CDS             7775..8239
                     /locus_tag="VLL59_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HER6509213.1"
                     /translation="MLRPLSKADCPSLKEINDKALGYCVSLDLVESQFERLIDDGHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNVLGLSLGLAVLPAYQRRGIGSALLRAL
                     ESQAKQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            8229..9485
                     /locus_tag="VLL59_001086"
     CDS             8229..9485
                     /locus_tag="VLL59_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HER6509214.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDTDTEMLNYEAIL
                     EQAKVVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            9492..10469
                     /locus_tag="VLL59_001087"
     CDS             9492..10469
                     /locus_tag="VLL59_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HER6509215.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKEVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            10470..11069
                     /locus_tag="VLL59_001088"
     CDS             10470..11069
                     /locus_tag="VLL59_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HER6509216.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            11079..12803
                     /locus_tag="VLL59_001089"
     CDS             11079..12803
                     /locus_tag="VLL59_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509217.1"
                     /translation="MKRLRPYVKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLVSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEVPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGEQK"
     gene            12800..14527
                     /locus_tag="VLL59_001090"
     CDS             12800..14527
                     /locus_tag="VLL59_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509218.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVIIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEEEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            14767..16137
                     /locus_tag="VLL59_001091"
     CDS             14767..16137
                     /locus_tag="VLL59_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HER6509219.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDTKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(16296..17279)
                     /locus_tag="VLL59_001092"
     CDS             complement(16296..17279)
                     /locus_tag="VLL59_001092"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HER6509220.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            17470..19956
                     /gene="gyrA"
                     /locus_tag="VLL59_001093"
     CDS             17470..19956
                     /gene="gyrA"
                     /locus_tag="VLL59_001093"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HER6509221.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIAEINTDRENSISKNKDN"
     gene            19976..>20711
                     /locus_tag="VLL59_001094"
     CDS             19976..>20711
                     /locus_tag="VLL59_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HER6509222.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYN"
BASE COUNT         6401 a         3655 c         4306 g         6349 t
ORIGIN      
        1 aggtaagttt ttacctaaat atacctctaa tcatcagagg tcataggaag attattttgt
       61 atagaggact tagagaagaa ggtgagaact gacttgtttt tcttaatcta tgttaaaaga
      121 ggagaaactt atgtttaatg acatccctgt atttgattat gaagatattc aactgattcc
      181 taacaagtgc attattacta gtcgttcaca agcagataca agtgtgacac tcggaaaata
      241 ccagttcaag ctaccagtta tcccagcaaa tatgcaaacc attattgatg aaacaattgc
      301 tgagcagttg gcaaaagagg gttattttta tattatgcat cgttttgatg aagatagccg
      361 caaacctttt atcaaacgca tgcatgaaca aggcttgatt gcatcaatct ctgttggggt
      421 taaagcttgt gaatatgaat ttgtgacctc tttgaaagag gatgctcctg agtttatcac
      481 cattgatatt gctcatggtc atgctaacag tgttattgat atgattaagc atatcaagac
      541 tgaattacca gaaacatttg tcattgctgg aaatgttggt acgccagaag ctgtacgaga
      601 actcgaaaat gcaggtgctg atgctactaa agtaggcatc ggtccaggca aagtatgtat
      661 cactaaagtt aaaaccggtt tcggtacagg tggttggcag ctagcagcac tgcgctggtg
      721 cgcaaaggca gctcgtaaac ctatcattgc tgatggtggg attcgcacac atggtgatat
      781 tgctaaatcc atccgctttg gagctagtat ggtcatgatt ggatcgcttt ttgcaggaca
      841 tattgaaagt cctggaaaaa cggtagaagt ggatggtgaa acgtttaaag aatattatgg
      901 ctcggcgtca gaatatcaaa aaggcgagca taaaaatgta gaaggcaaaa aaatcttatt
      961 gcctacaaaa ggtcacttat cagataccct gaccgaaatg caacaggatt tgcaatcgtc
     1021 catttcttac gcgggtggta aagatttaga cagtttgcgt catgttgatt atgttattgt
     1081 caaaaattcc atttggaatg gtgattccat ttaaatgata tggagttagc taggaccagt
     1141 aaagaatttt ttagcttaat gctggagatg cttttatcat atctctgtag gtattgaaaa
     1201 aaataagaaa catggtaaaa tagtaaatta tcataatgaa ttcaataatg acatacttat
     1261 ttatgctgtg aattggcgca gcgtctctac aagacacctt aatgtctaac aataagtaag
     1321 cttttaggct tgcttggttt ttaaccttgc aaagtgagaa actcttatag tttctcactt
     1381 tgcggcaggc tttttctatt tgaatcaaaa ggagatttat gcagttactt gaagaacgca
     1441 ccttaacaga tggcaatatt ctaggagaga atattctaaa ggtagataat tttttaactc
     1501 atcaagttga ttaccggttg atgaaagcaa ttggtaaagt gtttgctcaa aaatatgctg
     1561 aggctggcat tacaaaagtg gttacaatcg aagcttcagg tattgcacca gccgtatacg
     1621 ctgcagaagc aatggatgtt cctatgattt ttgcgaaaaa acataaaaac attaccatga
     1681 cagaaggcat tttgacagca gaagtttatt ctttcactaa acaagtgacg agcacggtgt
     1741 ctatcgctgg taaattccta tctaaagaag acaaggtttt gattattgat gactttttag
     1801 ctaatggtca ggcagccaaa ggcttgatcg agattattgg tcaagcaggg gcacaagtcg
     1861 tcggcgttgg tattgtgatt gagaaatctt tccaagatgg tcgtcgattg attgaagata
     1921 tgggcattga agtgacctca ttagcacgta ttaaaaactt tgaaaatggt aatctaaact
     1981 tcttggaggc tgacgcataa tgacacattc aacaaagcag gaacattctc actcgcaatc
     2041 agctgtcctt ggcttacagc atgtgctttc gatgtatgcc ggatctattt tagtaccaat
     2101 tatgatcgca ggtgctttag gttattccgc tagagagttg acctacctga tttcgacaga
     2161 tattttcatg tgtggtgtgg ctactttctt acagttaaag ttaaccaagc atacgggagt
     2221 gggattacca gttgttttag gatgtgcttt tcaatcagtg gcacctctat ccattattgg
     2281 agcgcaacaa ggttcaggtg ccatgtttgg agccctcatt gcgtcaggaa tttatgtcat
     2341 tttagtggca ggtatttttt ctaagattgc tcgtttcttc ccaccaattg ttacaggatc
     2401 ggtcattacc gttattggct taagtctcgt aggtgttgct atggggaata tgggagataa
     2461 cgtcaaagag cctacggcac aaagcatgat gttatcattg ttgacgattg tcattattct
     2521 tttagtccaa aaatttacca aaggttttgt gaaatccatt tccattttga ttgggcttgt
     2581 agtgggaact ttggtttcag ccatgatggg attagtagat acaactcctg ttgtagaggc
     2641 ttcttggatt catgtgccaa ccccatttta ttttggcatg ccaacttttg aaatcacttc
     2701 tattgtgatg atgtgtatca tcgcaacggt ttctatggtt gaatcaacag gtgtctactt
     2761 agcgctttca gatttgacta atgatcaatt agatgaaaaa cgtttgcgca atggttatcg
     2821 ctcagaaggg atcgcagtct ttctcggtgg gttatttaat accttccctt acactggttt
     2881 ttctcaaaac gttggacttg tccaaatctc aggtattaaa acccgtcgtc cgatttacta
     2941 cgcagcaggt atccttgtgg tcattggcct actccctaaa tttggagcaa tggcacaaat
     3001 gattccaagc ccagttcttg gtggagctat gcttgttctc tttggtatgg ttgctcttca
     3061 aggaatgcaa atgcttaatc gtgttgattt ccaaaagaac gagtataatt ttattatttc
     3121 tgccgtttcc atctcagcag gtttaggctt taatggcact aatctttttg ccagcttacc
     3181 agagacagct caaatgttct taacgaatgg tattgtgatt gccactttga catctgttgt
     3241 cttaaattta gttttaaatg gcaaagacaa acaagatgaa taattaaaaa acggctaatt
     3301 gagccgtttt ttctgtgatc agttttgagc aaaccgttaa ccccttttaa tgatagtatg
     3361 gttgaaaata gtgtctcaaa ccatttgaca taaggacatg gtgctttctt gttactagaa
     3421 gaccttcaat attatcaaag gtatttaaaa gtgtgataat cattgagcta tcaagaccaa
     3481 ataaacgggt agcccatatg tcacaataaa aagaagaagg agccatgatc gttaagctaa
     3541 gcatatttgt ttctataggg tagcctgtct gacgatctaa gatatgatga tactgtttcc
     3601 ctttggctgt aaactgcctt tcataaattc cagaagtcac aacagagtga ttgttaacct
     3661 tgatgacacc aagatgttgc ccacgtttag catctggttt ttgaatgcca attcgaaaag
     3721 tcttgtcagg gcttttcgga ttaggtccat gaacgcgtac atttccacct aaattaataa
     3781 gggcagagtc aataccatct tcaatcaggt aggccataat cttatcagta atataacctt
     3841 ttgctaaggc tcctaagtct aaagccattc ctacttgttg taaaaagaca gtctgttttt
     3901 tgtcatctat aagaacctgt ctaggatctg ttagagctaa ctgttgtgag ataaggttat
     3961 gactaggcac tctagcatct tcaaatccaa ttcgccaggc ttgaacaagt ggcccaatgg
     4021 cgatattaag attacttggt gttgacaagc tatgagcttt accaatttgg attaggttaa
     4081 ataaatcaga gtgaacgctg aggggtttaa caccagccgc ctgattaata gccatcaatt
     4141 cagagtttga atcattagct gaaaaacgat ttttgtaagt atataataag tcaatgactc
     4201 tacttagttg ttggcaagct ttgtcagatt cgatctgaat atcaataact gttcccatta
     4261 gctttaattg ttgcgtaaca aacataatta gtcctctttt tagcagaata cccccactaa
     4321 ggagtggggg aaggtcatta tgatttttgt ttcatttcac cttgaggata gtaagttcct
     4381 tcaggcatat cgttgataaa aacatggata ttttctttag gtgcttttgc aatgcgtgag
     4441 actacttcgg taacctcgcg agctaattga tttttttgtt cttgtgagcg tccctcaaac
     4501 aagtcaattg ttacaaatgg cataatgtta ctcctttatg ttattgggca tcattgtaac
     4561 ataatgctgt gaaaaagtat acactatttt caatggctgg gaaaacttca gcctttgtgg
     4621 taaaataggt agaatactat agaaagtagg attttccgct ttggctcaac tctattataa
     4681 atatgggaca atgaattctg gtaaaaccat tgaaatttta aaagttgctc ataactatga
     4741 agaacaaggc aaacctgttg tcattatgac aagtgctctt gatacacgtg atggttttgg
     4801 catcgtctca agccgtattg gtatgcgacg agaagctatc cccatttcca atgacatgga
     4861 tattttcaca tttattgccc aattggagga aaaaccttat tgtgtcctga ttgacgaaag
     4921 ccaattttta agcaagcaaa atgtttatga tttggcgcgt gtggtggatg agctaaatgt
     4981 tcctgtcatg gcttttggtt tgaaaaatga tttccaaaac aatctttttg aaggttcaaa
     5041 acatttgcta ttattggccg ataagattga tgaaatcaaa acaatttgcc aatactgtag
     5101 taagaaagca accatggttt taaggacaga aaacggaaaa cctgtctatg aaggtgatca
     5161 gatacaaatt ggtggtaatg aaacatatat cccagtttgt cgaaaacatt attttaatcc
     5221 agagatttaa aaggtaatcg gttttaaagg agatacaaag aaaaatgaat atttatgatc
     5281 aattgcaggc agttgaagat cgttatgaag agttaggtga gttacttagt gatccagatg
     5341 ttgtttcaga tacaaagcga tttatggaat tatcacgtga agaagctaat actcgagaaa
     5401 ctgtcacagc ttatagagaa tataagcaag tcattcaaac catttcagat gctgaagaaa
     5461 tgatcaaaga tgccagtggt gatcctgaat tagaagaaat ggctaaagaa gaacttaaag
     5521 aatcaaaagc agctaaagaa gagtatgaag aaaaattaaa aatccttcta ttacctaaag
     5581 atcctaacga tgataaaaac attattttag aaattcgtgg tgctgctggt ggcgatgaag
     5641 cagcgctttt tgctggtgat cttttaacaa tgtatcaaaa atatgctgaa actcaaggat
     5701 ggcgttttga agttatggaa tcatccgtta atggtgttgg tggtattaaa gaagtggttg
     5761 ccatggtttc tggtcagtca gtttattcta agcttaaata tgaatcagga gctcatcgtg
     5821 ttcaacgtgt cccagtgaca gagagtcagg gtcgtgttca tacttcaact gcaactgttt
     5881 tggtaatgcc agaagttgaa gaagtagaat acgacattga tcctaaagac cttcgcgtcg
     5941 atatttacca cgcgtctggt gctggtggtc agaatgtcaa taaagttgct actgcagttc
     6001 gtatggtaca cattcctaca ggaatcaaag ttgaaatgca agaagagcgt actcagcaaa
     6061 aaaaccgtga taaagcgatg aaaatcattc gtgctcgtgt tgctgaccat tttgcgcaaa
     6121 ttgctcaaga tgaacaagat gctgaacgta aatcaacagt tggtactggt gatcgttcag
     6181 aacgtattcg tacttataat ttcccacaaa atcgtgtaac agatcatcgt attggtttga
     6241 cacttcaaaa attagatact attttatctg gaaaaatgga tgaagttatt gatgcactcg
     6301 ttatgtatga tcagacaaag aaattagaat ctctcaataa ctaatgaact atgctacatt
     6361 aatcagaact tatgaagata aactagaaca aatagatgag gatcgcgaaa atctcgccta
     6421 tgtttttaga gaaatcaaag aatggtcaag tctagatatg ttgattcacc aaaatcaagc
     6481 tgtgactcct gaagatgctg ttcttttgga acatattttc tgttctctaa gtcagcattt
     6541 atctcctcaa tatattacag gtaatgctta ttttcgtgat ttgaagcttg cagtcgacaa
     6601 gcgtgtatta attccaaggc cagaaacaga agaattagtt gacatgattt tagctgaaaa
     6661 tcttgatgca ccgttgaatg ttttagatat tggtacaggt agtggagcga ttgctatttc
     6721 tctcaaaaaa gaaaggccta actggcaagt aacggcatct gatatttcta gagctgctct
     6781 tgacttggca aaagccaatg ctgatgctta ccagcttgat ataacgttta ttgaatcaga
     6841 tgtttttagt ctcatttcag gaacatttga tattattgtg tcaaatcctc cctacatatc
     6901 ctacgaggat aaggaagaag tcagtctaaa tgttttgcaa tcagagcctc atttggcact
     6961 ttttgctaaa gaaaatggct atgctattta ccgtaagatt attgaacaag ctgacaatta
     7021 cttaactaag gaagggaagc tttactttga aattggttat aagcaagctg aaggtataaa
     7081 agatatgtta caagcctatt ttcctcaaag acatatacga gtcgtaacgg atatatttgg
     7141 caaagaaagg atggtggttg ttgattatgg agtatctagc tagtatcatt gaatcaggtg
     7201 atgcccttgt tttaccaaca gaaacggttt atggtctttt tgccaaggct ttagatgaaa
     7261 aagcagtaaa tgctgtttat gacttaaaac aaagaccccg agataaagca atgaacctta
     7321 atgtggctga ttttaatagt atcttagcct tttcaaaaga acagccgaga tacctcaaga
     7381 aattatacca agccttttta ccaggtccgt taacgattat tttaaaagct aatgaccagg
     7441 ttccttattg gattaattcg ggactttcaa cggttggttt tcgcttaccc agtcatccaa
     7501 ttaccacagc tttaattcaa aaaacaggcc ctttaattgg tccttctgca aacttatctg
     7561 gcaaagctag tggtcgagtt tttgatcata ttatgcaaga ttttgacttt caagtgtttg
     7621 gttatgcaga tgatcctttt ctaacaggta aggattcaac catcttagac ttatcaggtg
     7681 agcgtgctgt gattttacgt caaggtgcta tcaccaaaga agaattatta gccaacgtgc
     7741 ctgaacttcg cttttaagag aggagccgct tggaatgttg agaccattaa gtaaagcaga
     7801 ttgtccatca ttaaaggaga ttaatgataa agccttaggg tattgtgtct cactcgattt
     7861 agtggaaagt caattcgaac gattgataga tgatggccat cattattttt tagcttatgc
     7921 cgacaaggat accaatcaat tattaggcta tgttcacgct gaacggtatg agacccttta
     7981 tgcttctgat ggtcttaatg tcttgggctt gagcttgggc ttggctgttt taccagccta
     8041 tcagagaagg ggaattggga gtgccttact aagggccctg gaatcccaag ccaagcagga
     8101 aggcattgcc tttattcgcc tcaattctgc cagtcatcgt aaagaagcgc atgcttttta
     8161 ccgaaacctc gactatgcag atgataaaac acaattacga ttcatcaaaa acttacaagg
     8221 agatgacaat gatttttgat aaaggtaatg ttgaagactt tgataaagag ctttgggatg
     8281 ccattcatgc tgaagaagaa agacaagaac atcatatcga attgattgca tctgaaaaca
     8341 tggtttcaaa agctgtcatg gcagctcaag gttctgtttt aaccaataag tatgcagaag
     8401 gctatccagg taatcgctat tatggtggaa cagaatgtgt ggatattgtc gaaacgcttg
     8461 ctattgaacg tgctaagaaa cttttcggtg ccgcatttgc caatgttcaa gcccattccg
     8521 gaagtcaagc caatgcagca gcttatatgg ccttgattga ggctggtgac accgtattag
     8581 gaatggattt ggctgcaggt ggtcatctca cgcatggctc tccagtaaat ttttctggaa
     8641 aaacctacca ttttgtgggt tactcagtag atactgatac tgaaatgtta aattatgagg
     8701 cgattttaga acaagcaaag gtggtccagc caaagcttat cgttgcaggg gcttcggcct
     8761 actctagaag cattgatttt gaaaagtttc gtgccattgc tgatcacgta ggtgcttact
     8821 taatggtgga catggctcac atcgctggcc ttgtagcagc aggtgtgcac ccgagtcctg
     8881 tcccttatgc gcatattgtg acatcaacaa cccataaaac cttacgtggt cctcgtggag
     8941 gcttgatatt aaccaatgac gaagctcttg ctaaaaagat taattcggcc gttttccctg
     9001 gtttacaagg aggacctctg gaacacgtga ttgctgccaa agcggttgcc ttcaaagaag
     9061 ccttggatcc agcctttaaa gactatgcac aagctattat tgataatact gcggctatgg
     9121 cagcagtttt tgcacaagat gatcgtttcc gtctgatctc aggtggtaca gataatcatg
     9181 tcttcttagt agatgtcact aaggttattg ctaatggtaa actagcgcaa aatcttctgg
     9241 atgaggttaa tattaccctt aataaaaatg ccattccttt tgaaaccttg tcgccattta
     9301 aaacctcagg tattcgcatt ggttgtgctg ccataaccag ccgtggtatg ggtgttaaag
     9361 agagtcagac cattgcccgt cttatcatca aagccttggt taatcatgat caagaaacta
     9421 ttcttgaaga agtccgtcag gaagtgcgtc agttaaccga tgctttccca ctctataaaa
     9481 agtaaggaat catgttagat agttatataa aacgtattgt cattcatcaa ttttctccca
     9541 atgacactga gttactgtta tcagatcgtt tagtgagcat tacaccacga attgatgaat
     9601 atttccggaa aaaattggct aaagtgttct cggatgaagc caaacggggt cagtttgagg
     9661 ctaataatac cttttttaca accattggtg atgatttgtt ggaaacgtct gttaccattg
     9721 cccagttatg gaaggaagcc tttgttattt cagaggatca aaaaaccaat gatttagtct
     9781 ttgtccagtt tgataaggat ggcgaaccct tttttgcttt cttgcgaatt gctttgaaag
     9841 aacagtttgc tcacctttct gacaattatg aacatccatt tacggtgacg cagaataatc
     9901 tgccgagtcc cacccagaca ccagatgaag cactagtcat taatctcaaa tctggtcagt
     9961 actacttgat tgaaaagcgt gtgaagcata atggcagttt tgctaattat ttttcagaac
    10021 acctcttgaa agttacacct gagcaatctg ttaaaaagtc tatcaaaatg atagaacaaa
    10081 ccgctcaaaa aattgcagag cattttaatc aagatgattt tacttttcag tcaaagatga
    10141 aatccactct ttttaagcag ttagaagcag acgacgtttt atcaccagaa aaattagctg
    10201 accaactctt tgatgataat ttaacagccc gtttaacctt tgtggatcaa gtcaaagaag
    10261 tcattccaga acctataaaa attagcgata ttgatcattc tagacagata aaaaaactag
    10321 aaaatcaaaa gctatcgtta tcaaacggga tagaattaac agtaccaaat gccatttatc
    10381 aggatgctga agcggttgaa tttttgttaa atgatgatgg gacttattca atcttgatta
    10441 aaaatataga ggatattaaa accaaataga tgtttagact tttaaagcgt gcctgcagtt
    10501 ttcttcttct ttttgtcatt tatcaatcct ttgttattca tcacaatgtt caacgtgttt
    10561 tggcatataa gcctatggtt gagaaaacat tagcagaaaa tgatacaaag gcaaatgtag
    10621 acttagtctt agctatgata tacaccgaga caaaaggagg agaagcagat gtcatgcaat
    10681 ccagtgaaag cagttcagga caaaaaaact cgattacaga tagtcaggcc agtattgagc
    10741 acggggtgaa tttactgtct cataatcttg ctctagctga ggaagcagga gtagattctt
    10801 ggacggctgt tcaggcctat aattttggaa cagcttatat tgattatatt gctaaacatg
    10861 gaggtcaaaa taccgttgat ttagcgacta cctattccaa aaccgttgtg gcgccaagcc
    10921 taggcaacac tagtggtcaa acctattttt attaccaccc cctcgccttg atttctggag
    10981 gtaagcttta taagaatggc ggcaatatct attactcacg agaagttcat ttcaatcttt
    11041 atttaattga actgatgagc cttttttaga aagttatcat gaaacgatta cgtccatatg
    11101 tgaaagggta cctaaaagaa agtatcttag gtcctctttt taaattatta gaagctttat
    11161 ttgaattatt agtccctttg ttaattgcta acatgattga tatatcgatt agtcaacaca
    11221 acagccaggg aattttgagg gttgttttaa cattatttgg tttagcaacc attggcttat
    11281 tgctttccgt tacagcccag tatttttctt cgaaagcagc tgttggtttt acaagacaaa
    11341 tgacagatga tttgtttaaa aaaatcatgt ttttgagcaa ggaggaccaa gaccatcttg
    11401 gttatgctag tctggtatca cgattgacca gtgatagttt tcaaattcaa actggtatca
    11461 atcaattttt gcgtcttttt ctaagggccc ctattatcgt atgtggtgct atggtaatgg
    11521 cttattggat tagtccaagt ctaaccctat ggtttgtgat gatggtgatt gtcttactaa
    11581 cacttgtttt tgttatgtca catttattag gtccccttta tctcttaatc cgccgagaaa
    11641 cagatcactt ggttcgtttg actagccaac agttacaagg aatccgagta attaaggctt
    11701 ttaatcaaac ccaaaaagaa ctccaagcat ttaagcagca aaatatgctc ttaagtcgcc
    11761 accaatatca agctgctacc ctagccaatg tcttgaatcc tatgactttt ttagtggtca
    11821 atcttactct gttaatcttg atttggcaag gaagttggca agtagctcat agatcgctta
    11881 gtcagggcat gttggttgct ttaattaatt acctcttgca gattttggca gaacttttga
    11941 aaatgaccat gttgatggga accatcaatc aaagtgtaac agccgcaaaa cggattaatc
    12001 aggtgtttgt tttagctgat gaagtgcctt tgcccttact taaagatggt cctatttcaa
    12061 ctcatctgtt gaccatccgg cacttgacct ttacttatcc aggagcagca gagccaagtc
    12121 tgtatgatat tcagttaagt gctgatcagg gagaatggat tggcatcatt ggtggtactg
    12181 gagcaggcaa aacgactttg attgacttga tctgccaaac ttattcacaa tatagtggtg
    12241 agattagtct taattggcaa ggagaagtgc caaaaacact aaccgagtgg cgaaatgtga
    12301 ttgctcttgt tcctcaaaaa gctcaattat ttaaaggaac gattagaagt aacctcctac
    12361 tgggacaatc aatgcctatt agtgatgagg aactgtggcg ggctcttgaa ttggctcaag
    12421 caaaagagtt tgtcgctgcc ttaccagaac aattagaggc acctgttgaa gccttcggcc
    12481 gtcatttttc aggagggcaa cggcaacgtc tagctattgc cagagcactt ctgaagccaa
    12541 aacccatttt gattttggat gatgccagtt ccgccttaga caatgagact cgaggacgac
    12601 tttttaaagc tctaaaagaa gagttatcag atgttttagt gattctagtc acgcaatcta
    12661 ttaagaattt gcagtttgct gataagattt tagtgttgga acagggccat caattggatt
    12721 ttgccagtca tgaccagtta aaagtaagca atgcacttta tcaagaaatg ctagcgcttt
    12781 acgtgaaggg ggagcaaaaa tgattaaaac agatcatcac ctcctaaagc gagtgcttca
    12841 ggatttgtta aaaaaacctc tacctgtttg tattctcgtg atcgctagtt ttgtacaagt
    12901 tggtttaagt gtttacttgc ctgttcttat cggtaaagcc gttgatatga gtttgtcagt
    12961 caattcttgg caaactttaa aatggctgtt ggggcaaatg ttagttatta ttgtggtcaa
    13021 cacattgatt caatgggtga tgcctcttgt ctatagtcgt ttgctatatc aatatagcca
    13081 gcaattgaaa gataagcttt tggaaaaaat tcatcgtctt ccttttgcat atctagatcg
    13141 tcaaaccatt ggagatttgg ttagtcgagt gataaccgac actgagcaac tgatcaatgg
    13201 tctacaaatg gtttttaacc agtttatact tggactattg acgattctgt gtaccattat
    13261 agctatggca cagattgact ggctcatgtt aatcttggtt ttggtgttaa caccaagctc
    13321 cctcttttta gctcgtttta ttgctcaaaa gagttttcat tatgcacaag cacagaccaa
    13381 aagcagagga aatttagctc agtttactga agaaatcctt cgtcaagaag gtttggttca
    13441 actgtttaat gctcaagagc agtctatctg tgattatcat gttttaaata aaacctattg
    13501 cgaggcttca caaaaagcca ttttttacgc ctcaacagtc aatccagcca ctcgctttat
    13561 taatagtgtc atttatgctt tactggcagg tttaggggct gttcgtatca tggctggact
    13621 tttttcagta ggtcagctaa ccactttttt aaacgttgtt gtccaatata ccaaaccttt
    13681 caacgatatt tcatctgtct tggcagagat acagagttct ttagcttgtg cgcaaaggct
    13741 ttatgacctt ttagatattg aaataaaaga ggaagagcac tttctaacat ttaaggcatc
    13801 agcggttaag gggcaaattg actttgaaga agtaagtttt tcttatcaaa aagacaggcc
    13861 cttactgaag gatattaatt tttctgttcc tgcgggttcc aaggtagcga ttgtagggcc
    13921 tacaggtgca ggcaaatcga ctttaatcaa tttactcatg cgcttttatg aacttgatgc
    13981 tggtagcatc aagttagata aagttcctat taagtgttat gctaaggaag aacttaggtc
    14041 cattactggc atggtattgc aagaaacctg gttgaaagat gcgactgttc atgagttgat
    14101 tgcttacggc agtgaagagg ctagccgtga tgaagtagtg gcagcagcca aagcagctca
    14161 tgcacacttc tttattatgc agcttcctaa gacttatgat acttacttaa gtgcttctga
    14221 tgatgctttg tcccaagggc agctccagtt attagctatt gctagaatgt ttttgaaaaa
    14281 accaaaagtc ttgattctag atgaagccac ctcctctatt gatattagaa cagaagctgt
    14341 tattcaagag gcactaaaag aactcatgag aggaaggacc agctttatca ttgcccatcg
    14401 tttatcaacg attcaatcag ctgatttgat tcttgttatg gatcaaggtc gattggttga
    14461 gtggggaaca catgccagct taatgtcaaa aaacggctgt tatgctagat tacaaaagat
    14521 agaataaagt tcgtctttta acaaaggtga actttttaag tcttcctaaa gttagttaat
    14581 taacaaactt taaactgtta tataaaaaaa taacagcgaa aaagcggacg atctttttta
    14641 taagtgagaa aaaacagttg actaaagaag aaataactca aaaaagtgag caatatattt
    14701 ggaagcgttt tttaactgtg gtataataga gccctatata atattgtgaa atgaggaaca
    14761 aaatatatga gtaaaatcgt tgttgttggt gcaaaccatg ctggtacggc ctgtatcaag
    14821 actatgttaa caaactacgg tgatgctaat gagattgttg tatttgacca aaactcaaat
    14881 atttcatttt taggctgtgg tatggcactt tggattggtg agcaaattgc tggaccagaa
    14941 ggacttttct attcagataa agaagaatta gagtctttag gggctaaagt ttacatggaa
    15001 tcacctgttc aatcaatcga ctacgatacc aaaacagtga cagcgcttgt tgatggtaaa
    15061 aaccacgtgg aaacttacga caagttgatt tttgcaactg gctcacaacc tatcttacca
    15121 ccgattaaag gtgccgaaat caaagaagga tcacttgaat ttgaagcaac tcttgaaaat
    15181 cttcaatttg tgaagttata ccaaaactca gctgatgtga ttgcaaagct tgaaaacaaa
    15241 gacattaaac gtgtagccgt agttggtgct ggttacattg gtgttgagtt agctgaagct
    15301 ttccaacgca aaggcaaaga agtggttctg attgatgtcg tggacacttg cttggcaggt
    15361 tattacgacc gtgatttgac tgacttaatg gctaaaaaca tggaagaaca tggtattcaa
    15421 ctagcctttg gtgaaacagt taaagaagta gctggtaatg gtaaggttga aaagatcatt
    15481 actgacaaaa atgagtacga tgtggatatg gttatcctcg ccgttggttt ccgtccaaac
    15541 acaactcttg gaaatggtaa gattgatctt ttccgtaatg gtgctttcct tgtcaataaa
    15601 cgccaagaaa cttctattcc aggtgtttat gctatcggtg actgtgcaac tatctacgat
    15661 aatgctactc gcgatacaaa ctacattgct ttagcttcaa atgctgtccg tacaggaatt
    15721 gtagcagcac ataacgcttg tggtacagac cttgaaggta ttggcgttca aggttcaaac
    15781 ggtatttcca tttacggctt gcacatggta tcaactggtt tgactcttga aaaagctaaa
    15841 cgacttggtt ttgatgctgc agtgactgag tatactgata accaaaaacc tgaatttatc
    15901 gaacacggta acttcccagt aaccattaag attgtttacg ataaagactc acgtcgtatc
    15961 ttgggtgctc aaatggcagc ccgtgaagat atgtcaatgg gaattcacat gttctcactt
    16021 gctatccaag aaggagtgac cattgaaaag ttggcattaa ctgatatttt cttcttacca
    16081 catttcaaca aaccttacaa ctacatcaca atggcagcac ttggtgccaa agactagtat
    16141 ctgataggaa aaagccagag cagttcagca gcactggctt ttttgctttt taattgttgc
    16201 aacctgaaaa gttctaaact tatgattatc ctcttatagc acgttggaaa aggaatatca
    16261 ggcaaaacaa aaagagaccg aagtctcttt tgtgattagt ttttagcagc agaagcaaat
    16321 tcttccttag caaaggcttc atcaatgata gctttcaatt gatttgcaga ggcttgcatt
    16381 ttttgcaatt cagcatcgtt aagtggaatg tttactggac gaacaattcc atacgctcca
    16441 acgatagctg gttgaccaat atagcaatct tcaacacctt cgtattggcc ttcttggaaa
    16501 acagaaagcg gaagaacagc attttcatca tcaagaatag cttttgtaat acgagctagg
    16561 gcaactgcaa taccgtagaa agtagcacct tttttattga tgattgagta agcagcatca
    16621 cgtacagaaa tgaaaagatc aactaggcct tgctcatcaa tgtcacgatt agcttggagc
    16681 cagtcgtaaa gacctacacc agcaacgtta gcgtgtgacc aaacagcaaa ttcagagtca
    16741 ccgtgttctc ccatgatgta agcgtgaacc gaacgcgcat caacaccgat tttagcagcc
    16801 agagcttgac ggaaacgggc tgaatctaga gatgtacctg aaccaatgac acgctcttta
    16861 gggaaacctg agaatttcca tgttgagtaa gtcaaaacgt caactgggtt agcagcaaca
    16921 agaaagattc ctttgaaacc agatgcaacg atttgtgtaa caacctcttt attgatacga
    16981 aggttttttt caaccaggtc aaggcgtgtt tcacctggtt tttgaggagc accagctgtt
    17041 aagacaacaa gatcagcatc atgacagtct gagtagtcag ctgcatagat ttttttaggt
    17101 gatgtaaaag ctagagcgtg gcttaaatct tctgcatctc cttgagtttt ttctttaaaa
    17161 atatcaataa taccaagttc ttgagcaata ttttgtgtta ccaatgcaaa agcgtatgat
    17221 gaaccgacgg caccatcacc gaccaagatt acttttttgt gttgtttagt tgcagtcatt
    17281 tctaaacatc tccttaattt tattagagca aaagctcata cggtcttatt ttaacatatt
    17341 gataattgtt tgtcattgaa ttcagaaaaa taatgaaaat agtttactga taacgcttcc
    17401 aataagaaaa aataaggaat ttatggtata atgaaatcta gtattgacta gaaaaggagc
    17461 attccttaaa tgcaagatcg aaatttaatt gacgtcaatc tgacaagtga aatgaaaacg
    17521 agtttcattg actatgccat gagtgtcatt gtggcaagag ctttgccaga tgtgcgtgat
    17581 ggtctgaaac ctgtgcatcg tcgtattctc tatgggatga atgaactcgg tgtgacacct
    17641 gataaaccgc ataaaaaatc tgctcgtatt acgggtgatg tcatgggtaa atatcacccg
    17701 catggggatt cttctattta tgaagctatg gttcgtatgg ctcagtggtg gagttatcgc
    17761 catatgcttg ttgatggcca tggcaatttt ggttctatgg atggtgatgg tgctgccgct
    17821 caacgttata ctgaagcgcg catgagtaaa attgcgcttg aattattaag ggatatcaat
    17881 aaaaataccg ttaattttca agataactac gatggaagcg aaagagaacc agtagtatta
    17941 ccagctcgct ttcctaattt attagtcaat ggagcgacag ggattgccgt tgggatggca
    18001 actaacattc cgcctcataa tttggcagag tctattgatg ctgtcaagat ggtaatggaa
    18061 catccagact gtacaacaag agagttgatg gaagtgatcc ctggacctga ctttccgact
    18121 ggtgcccttg ttatggggcg ctcaggtatt catagggctt atgatactgg taaaggttct
    18181 atcgttttac gctctcgaac agaaattgaa acaactcaaa caggtcggga acgtattgtg
    18241 gttactgaat ttccctatgg cgtcaataaa acgaaagtgc atgaacacat tgttcgttta
    18301 gcacaagaaa aaagactaga aggtattaca gcagttcgtg acgaatctag ccgtgaagga
    18361 gtgcgttttg ttatcgagat tcgtcgagag gcatccgcga cagttatctt aaataacctc
    18421 tttaaattaa caagccttca gacgaatttc agttttaata tgttggctat tgaaaatggt
    18481 gtgcctaaaa tattgtcact cagacaaatc attgataatt acattagtca tcaaaaagaa
    18541 gttattatac gtcgcacccg atttgataaa gataaagctg aagccagagc tcatatttta
    18601 gaaggcttac tgattgccct tgatcattta gacgaagtga ttgctattat tcgtaacagt
    18661 gagacagatg tcattgctca gacagaattg atgtcacgtt tcgacttgtc tgaacgccaa
    18721 agccaagcta ttttggatat gcgtttgcgt cgtttgactg gtttggaacg tgataagatt
    18781 caatcagaat atgatgattt gttggccttg attgctgact tatctgatat tttagccaaa
    18841 ccagaacgta ttatcactat catcaaagaa gaaatggatg agatcaagcg taaatacgct
    18901 aacccacgcc gtacagaatt aatggtcggt gaagtccttt ctctagaaga tgaagaccta
    18961 attgaagaag aagatgtttt gattaccttg tcaaataaag gttatatcaa gcgtcttgct
    19021 caagatgaat ttcgtgccca gaagcgtggt ggacgtggcg tccaaggaac tggagtcaac
    19081 aatgacgact ttgtccgtga attggtatca acaagtaccc atgatacttt gctcttcttt
    19141 acgaattttg ggcgtgtcta tcggttgaaa gcttacgaaa ttccagaata tggtcgtaca
    19201 gcaaaaggtc ttccaattgt taatctattg aaattagaag atggtgaaac cattcaaact
    19261 attatcaacg cacgtaagga agaaacagca ggtaaatcct tcttctttac aacgaaacaa
    19321 ggcattgtca aacgtacaga agtttcagaa tttaataata tccgtcaaaa cggtctccgt
    19381 gctcttaagt tgaaagaggg agatcagctg attaacgtcc ttttgacaag cggtcaggat
    19441 gatattatca ttggaactca ttccggatat tctgttcgtt ttaatgaagc aagcatccgc
    19501 aacatgggcc gatcagctac gggtgttcgc ggggttaagc ttcgtgaaga tgatcgcgtt
    19561 gttggcgcgt cacgtattca agataaccaa gaagttcttg taattaccga aaatggcttt
    19621 ggtaagagaa caagtgctac agactatcct acaaaaggta gggggggaaa aggaataaaa
    19681 acagctaata ttacccctaa aaatggtcaa ttagctggat tggttaccgt agatggtaca
    19741 gaagatatca tggtgattac aaataaaggt gtcattattc gcacaaatgt tgcaaatatt
    19801 tcgcaaacag gtcgtgctac tttgggtgtt aaaattatga aactagatgc tgatgctaag
    19861 attgtaacat ttaccttggt tcagcctgaa gatagtagta tcgctgaaat caatactgat
    19921 cgtgaaaata gtatttcaaa aaataaagat aattaatcat aacaaggagt aaaaaatggt
    19981 aaaaaaacaa aagcgtcgaa aaataaaatc catgtcttgg gcaagaaaac tactaatagc
    20041 tgtactttta attctaggtt tagcattgct ttttaacaaa cctatccgaa atacattaat
    20101 tgctcgaaac tctaataaat atcaagtaac gaaagtttcg aaaaaacaaa tcaaaaagaa
    20161 taaagaggct aagtcaacat ttgatttcca agccgtagag ccagttagta cagagagtgt
    20221 cttgcaagca caaatggcgg ctcagcaact tcctgttata gggggcattg ccataccaga
    20281 gcttggcatt aatttaccaa tttttaaagg tttaggaaat actgagctta tttatggcgc
    20341 aggaacgatg aaagaagaac aagttatggg aggagaaaat aattattctc ttgccagtca
    20401 tcatattttt ggaattacag gttcatctca aatgctcttt tcgccgcttg aaagagcaca
    20461 aaatgggatg tccatctatt taacagataa agaaaaaatt tacgaataca tcataaaaga
    20521 tgttttcacg gtagctcctg aacgcgttga tgttatcgat gatacagctg gtctcaaaga
    20581 agtgacttta gtgacttgta cagatatcga agcaacagaa cgtattattg tcaaaggaga
    20641 actaaaaaca gaatacgatt ttgataaagc gcccgccgat gtattgaaag cttttaatca
    20701 ttcttataac c
//
LOCUS       DAUNLR010000028        20523 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUNLR010000028 DAUNLR010000000
VERSION     DAUNLR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20523
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.028"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            37..1233
                     /locus_tag="VLL59_001095"
     CDS             37..1233
                     /locus_tag="VLL59_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HER6509223.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCNVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            1735..2583
                     /locus_tag="VLL59_001096"
     CDS             1735..2583
                     /locus_tag="VLL59_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HER6509224.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(2918..3814)
                     /locus_tag="VLL59_001097"
     CDS             complement(2918..3814)
                     /locus_tag="VLL59_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HER6509225.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYLGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            4112..4864
                     /locus_tag="VLL59_001098"
     CDS             4112..4864
                     /locus_tag="VLL59_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HER6509226.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKINQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            4849..5799
                     /locus_tag="VLL59_001099"
     CDS             4849..5799
                     /locus_tag="VLL59_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HER6509227.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADATVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKGNKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(5979..8306)
                     /gene="pflB"
                     /locus_tag="VLL59_001100"
     CDS             complement(5979..8306)
                     /gene="pflB"
                     /locus_tag="VLL59_001100"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HER6509228.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLVYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDKNGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            8516..9610
                     /gene="dinB"
                     /locus_tag="VLL59_001101"
     CDS             8516..9610
                     /gene="dinB"
                     /locus_tag="VLL59_001101"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HER6509229.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTNNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(9703..10185)
                     /locus_tag="VLL59_001102"
     CDS             complement(9703..10185)
                     /locus_tag="VLL59_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509230.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIIFCTQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILAQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(10276..12639)
                     /locus_tag="VLL59_001103"
     CDS             complement(10276..12639)
                     /locus_tag="VLL59_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HER6509231.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESGSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFTITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVILGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTYFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QSTNSNPTENSQSDNDDFRLTPENYSTIDSMIGLTESDIALFFQKKS"
     gene            complement(12697..13290)
                     /gene="lepB"
                     /locus_tag="VLL59_001104"
     CDS             complement(12697..13290)
                     /gene="lepB"
                     /locus_tag="VLL59_001104"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HER6509232.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(13301..14203)
                     /locus_tag="VLL59_001105"
     CDS             complement(13301..14203)
                     /locus_tag="VLL59_001105"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HER6509233.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            14360..14668
                     /locus_tag="VLL59_001106"
     CDS             14360..14668
                     /locus_tag="VLL59_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509234.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            14671..15216
                     /locus_tag="VLL59_001107"
     CDS             14671..15216
                     /locus_tag="VLL59_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HER6509235.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYTLSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            15365..17704
                     /locus_tag="VLL59_001108"
     CDS             15365..17704
                     /locus_tag="VLL59_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HER6509236.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELSELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEESRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPEISNDSTLALINVRHPLLSNPVANDLHFDQDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSNIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG"
     gene            17708..18208
                     /locus_tag="VLL59_001109"
     CDS             17708..18208
                     /locus_tag="VLL59_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HER6509237.1"
                     /translation="MESYEHFYAKLSQPFRKTPQLIILLNVLLKIITGVMYILYPSFL
                     IFTFWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSALLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            18289..18603
                     /gene="trxA"
                     /locus_tag="VLL59_001110"
     CDS             18289..18603
                     /gene="trxA"
                     /locus_tag="VLL59_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HER6509238.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(18655..19242)
                     /locus_tag="VLL59_001111"
     CDS             complement(18655..19242)
                     /locus_tag="VLL59_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509239.1"
                     /translation="MEIGQQIIRYRKQQALSQEKLAEKVYVSCQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSNGKLLDEIEKREE
                     RAKLPYQKPLIVTVFFLITVAFAFASRFMFTWLFH"
     gene            complement(19318..20442)
                     /gene="mutY"
                     /locus_tag="VLL59_001112"
     CDS             complement(19318..20442)
                     /gene="mutY"
                     /locus_tag="VLL59_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HER6509240.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
BASE COUNT         6260 a         3572 c         4148 g         6543 t
ORIGIN      
        1 aaaatgttta tgaaaataga gaggagttca ttttcaatgg aagaaaaatt gtttaacaaa
       61 cattttgtgg ccatcacagt aataaacttt atagtctata tggtctacta tctttttacg
      121 gttattattg cctttgtggc gactagagag ctaggagctc agactagcca ggcaggattg
      181 gcaacaggga tttatattct agggacttta ttagcccgtt tgatttttgg aaagcagttg
      241 gaggtgtttg gtcgtcgttt ggttttaaga ggaggtgcta ttttttacct cttaacgacc
      301 ttagcctact tttatatgcc aacgattagc atgatgtact tggttcgttt cttaaacgga
      361 tttggttatg gtgtggtatc aactgcgaca aataccattg taacagccta tattccagct
      421 tgtaaaagag gagaaggaat taatttttat ggcttgtcaa ctagtctagc agcagctatt
      481 ggcccttttg taggaacctt tatgttggat aatcttcata ttgattttcg catgattatt
      541 gtcttatgta acgtcttgat tgggtgtgtg gttgttggtg cttttgcttt tccagtcaaa
      601 aacatgtctt taaatgcgga gcaattggct aaaaccaaat cgtggactgt ggatagtttc
      661 attgagaaaa aagccttgtt tatcactgca atcgcctttt taatggggat tgcctatgct
      721 tcagttttag gatttcaaaa attatacacg tctgaaattc atttgacaac agtaggcgct
      781 tatttctttg tggtctatgc cttaattatt accatcactc gtccagcaat gggacgttta
      841 atggatgcta aaggcgataa atgggtcttg tacccaagtt atcttttttt agcaatggga
      901 ctcttcttgc taggtagtgt atcgtctgga ggaagctatt tgctttcagg agccttgatt
      961 ggctttggtt atggcacttt tatgtcttgt ggtcaagccg cctccataca aggagtggat
     1021 gagcaccgct ttaatacggc tatgtctact tatatgattg gtcttgattt aggtttaggt
     1081 gctgggcctt acctcttggg cttgattaaa gatttggcac ttggtagtgg tgtggcttcc
     1141 tttaggcact tattctggtt agctgctgtg attccactga tttgtacctt gctttactta
     1201 ttaaaaacaa agacaagaca ggttgtgtct taaggacaag aaaaggagtt tagtcttata
     1261 cttaaataca aacgtatctt aacagctgta gatagttcct atgagccggg attagctgtg
     1321 ggtaaagcca ttactatagc gctttgaaat aattctagtt tgctattcgt acatgtcaat
     1381 aaaaatgact cgcaaaagcc attcgtgaaa gagaaaatgt ggccttattt ttagtaggta
     1441 caattggatt aagcacgttt agatacatga caattggatt aacatcagaa tataggcttt
     1501 gtcatgttaa gattgatctg ttgatagtga gagctaataa aaaatgttat aatactatga
     1561 aataaagtga taaagataag gccttttatg gtccttttct ttaccgcttt tattattgtg
     1621 tgaaaataac acttaatgat cattttattt attattttat tacctttaca ttcatcaata
     1681 agcctgttaa aatggtattt gttatatttt attatttgga ggaaaccaga aaacatggaa
     1741 atgacatgga ctgtgaaata catcacagaa tttatcgcaa cggctttttt gattattttg
     1801 ggaaatggag ctgttgctaa cgtcgactta aaaggaacaa aaggacataa ctcaggttgg
     1861 ttagtgattg cttttggcta tggcttagga gttatgatgc cagctttgat gtttggtaat
     1921 gtatctggaa accatattaa tcctgctttc acagttggac tagcagtatc aggcttgttc
     1981 ccatgggctc acgtcttaca atacgttgtg gcacaattac ttggagctat ctttggtcag
     2041 ttggtagtgg taatggttta taaaccttac tttatgaaaa ctgaaaatcc aaatcatgtt
     2101 ttaggctcat tctcaacgat ttcatctctt gataatggtc aaaaagacag tcataaagcc
     2161 tcttatatca atggtttctt aaacgaattt gtaggttcat ttgttctttt ctttggtgct
     2221 ttggctttga ctaaaaacta ctttggggta gagttagttg gtaaattgat tgaagcaggc
     2281 tacgaccaaa caactgcagc aacacaaatt tcaccatacg tgacaggctc attggcggtt
     2341 gctcacattg gtattggttt cttagttatg gtcttggtta cttcattagg tggaccaact
     2401 gggccagcac taaacccagc gcgtgatttt gggcctcgtt tgttacacca cttcttacca
     2461 aaatcagttc ttggtcaagc caaaggtgat tcaaaatggt ggtatgcatg ggttcctgta
     2521 gttgcaccta tcttagcggc gatagtagcc gtagcagcgt ttaaatacct ttatatcaga
     2581 taaaaaaaga actaaagctt cttttagact caagacaagc tcgcttaagg aacttgtctt
     2641 ttttatatga gttaagcgaa atctaatgca aacttgactg tcttgtatag cgtattttgt
     2701 aaattttatt agacttcttg taaaaagcct ctcctcagat aagatgacta atgcctctaa
     2761 acggtgttac aaataaacga ggcatcccta acttccttta tctggtgttg aaactatttt
     2821 gcacggacta aatcactgac agagtaaaaa acgatttttc atttttgttg taaaatatta
     2881 aaaacgtctc tggttagtga tttccagaaa cgttatctta tctatttgtt tgttgcttat
     2941 gagaggtaaa ggaggaacga atcagcattc caccagtgaa gaaaacgata gcgatgacca
     3001 gaagtttcaa gctattaata tctaaatttg ttaagaaaaa cacagctagt aaaacgccaa
     3061 taataccacc agaaacaatt ccagcaaaac catcccaact gacacggttt gctttgataa
     3121 actggctact agaagctgtc ataatcatag ctgcatctag catcataaca ggcatagcaa
     3181 ctgttgggct aagacccatt aatgaaaaga aaatcaattc tggagcataa ttgcctaacc
     3241 ccatagtcat caagactcca acgataaaat taaaaccaat tccaacaaaa agccagatgc
     3301 catggaggcc atgaatggtg tctgaaaggt gttctcctgg atggtagatt attctaatga
     3361 tcatgattat agctgctatg attaaaagac taccaaggat tcgttggaca gttggagcat
     3421 gccagttttt tgtaatatga gtccccaaat aagctccaat aaaggctgct gcagccatag
     3481 caagtaaagt tagaacctca acttttacga caaaaataaa gcaaagagat tgaatgagca
     3541 ccggaagcac atgagctacg gtcatagtgc caggcaattg tctatcgtca gtgactaatt
     3601 tagttaactt aaagcacgtt gtggtagtag caaaagaccc tatcccaagg gtgtcaaggg
     3661 catctgttag caggccaatc caaaaccccg tccaaaagcg tttaaaagga ttgatcttat
     3721 tttttttaag atgttttact aacataaaga aaataaaaag cattgccgaa actagcaaag
     3781 cttgtatcag tctaaggata agcatttcgt tcataaagac tagtttacaa aaaaaaacct
     3841 tagccgtcaa cgtgatttac ttcattaaaa catgccacta tgcttagaag agctttggtt
     3901 cgatgtattt tgttaaaatt aagctaaaat attaatattg catgaaaggg gacgccttcc
     3961 tttttccctt actgagctta gctgttattg tagtgaatgt ttaaaaggct agtttgtcgc
     4021 tctttatcaa aaatctagta ggatgaatac gtataatttc ttgtcaaata gaggaatttt
     4081 gtctataata gcagaggatt aggaggaaat tatgacttta atggaaaata ttacctttaa
     4141 aactccagta ttacgcgtta atgatcgcga ccttaatatt gcattttatc aaaataattt
     4201 agggcttcgt ttagtatctg aagaaaatgc gattgctatc ttttcatctt ggggagaagg
     4261 gcaggaatgt tttgtaattg aagagtcacc ttcagttaga acgcgtgcgg tagaaggccc
     4321 taaaaaggtt aatacgattg tcatcaaaat aaatcaacct aaagaaatcg aacaattatt
     4381 agctcatgga gcacattatg acgctctttt taaaggtcaa aatggctatg cctttgagac
     4441 tatttcccca gaaggagacc gattcttgtt gcatgctgaa caagatatta aacatctcca
     4501 aggtactgat ttaccatcgc ttgaaaaaga tgcgactttt aaaggtttaa ctcaatttaa
     4561 gtttgatatt attgttttaa atgttattag tgaagaacgc tcaaaagctt tttatcggga
     4621 tctgtttagt gatcagttac ctattactat ggattttatt caagaagaag gtcccgattt
     4681 ggcaattgat ccccatattg cttgggattt agaaatttta gaatttcaag tctcaaagga
     4741 ctatgatatg aaggtcctaa aagcaacttt agaagaagac gggcacaagg tctacattga
     4801 taaaaaacac aaagtattgg tcctttctga tccaagtcag atcgaagtat ggtttacgaa
     4861 atgactttgg cagtcattaa atgtattgaa aaccatcttc acaaaaaagt atacaaaggg
     4921 gccagtctgg ctctctttca atctggtcga tggcaagaat accatatcgg aacaattgat
     4981 ggaagacgac cagttgatgc taacttagtt tatgacttgg ctagtgtttc aaaagttgtt
     5041 ggtgtggcca caatatgcaa tattttattg aataatggta cgttagcatt agatgatccc
     5101 ttaaaagtat attatcctag tattgctgat gcgactgtca ctattcgaca gttattgact
     5161 cataccagtg gtcttgatcc ttatattcct aacagagatg ttttaaatgc acaacaatta
     5221 agaaaagcac ttaatcatct tactcaaaaa ggaaataaaa acttttatta cacagatgtc
     5281 aatttcctct tgttaggctt tatgttagaa gagctcttta gtgaatcttt agaccagata
     5341 tttgacaaga ctatctttac tccctttggg atgtatcata cgtcttttgg ccctcgtcca
     5401 gaagctgtac caacattaaa gggtgtgagt gatggggaag ttcatgatcc caaagcaaaa
     5461 atcttaaaaa aacattctgg atctgcgggg ctattttcaa ctcttgcaga tttagaaagt
     5521 tttagcaatc attatcttaa tgatccattt tcagattgtc tgtggcgcaa ctacagccaa
     5581 caaacaattg agcggtcact agggtggaat ttagatggcg attggattag tcatacaggt
     5641 tacacagggc cgtttctaat gcttaataaa aaagagcaaa cggcagctat ttttttgacc
     5701 aaccgtactt acgacgagga tgataaaagt aaatggttaa aagaacgtca gttgctttac
     5761 aatgcactaa agcatgatct gacaacaccc gtatcgtaac gtctaaaggg gcagttttag
     5821 tgatcttatt actgttttta aagtttcttc taaaaaatag ccatttcatt tgtctgatga
     5881 gattagagtg attataagtg aaaaaagaac agccatctca ttttgaatca aatgagatgg
     5941 ctgttctttt ttataagtta ttgatcattt agatactact atttacttga aatagcttca
     6001 gcggcatcat ccattgaaag cacttcgtgg aagacacgtt gagtcaattc agttttttgt
     6061 tctggtgtaa ggtatttggt gttgacacag taaccagaga tacgcacgat aacgtcttcg
     6121 ccgttcatga ttttgtcata aacatcgtta aggtccataa cgttcaagtt aacgtgctga
     6181 ccaccatttt caaagtaacc gtcaagcact gttaccaagt tgtcaacttg ttcgtcaaat
     6241 gttttaccaa gagcacgagg tgatacttga gtagtcaatg agataccatc gttagcatgt
     6301 gagaattcca gtttagcaag tgagttaagg ttttgtaacc agccaccttt tgctttgtta
     6361 gatgggttag cacctggtga gaagaattcc acttggctag tgttaactgt accatcttcg
     6421 tttaagaaga cgccgcggtg aactggagag ttaccagttt gtttagagta agcaacgttt
     6481 gaagtgatgg taagaagtga tactgaagcc tcagcattct tgtaaagttt gtggcttgca
     6541 agacgtgtgt ggtaagcttc catcaaccat ttcgcgatgt catcaacacg gtcgtcatct
     6601 tcaccgtaac gagggaagtc acctgttact tcgtagtcat aaatgtagcc atttttatcg
     6661 cggatagttt taacagttgc gtatttaata gctgacaagg tatcaactgt gttagcgaaa
     6721 ccacagatac cgaatcccat gttagcacgt tggtgtgttg gcaagaaggc catttgaact
     6781 gcttcgtagt tgtatttatc agtcatgtag tggatgatgt taagcgcatc tacataagta
     6841 tctgtcaacc agtcaagaga tttctcaaag ttagccataa cttcgtcgta cacaaggact
     6901 tctgatgtga ttggttcaac aacgttaaac actttgtagt ctctgtgaac atcatcgtaa
     6961 ccaccgttaa gaccagtaag aagggctttg agaacgttta cacgagcacc gaagtattgg
     7021 atgttatgac gttgttcttc attttctggg tcaagtggtg atacacaaca tgaaatacat
     7081 gacatttcac cataaccttc tttagccatt gttgtcacac cttcatattg gatagaagag
     7141 tgtttgtggc tcattttcat acagtagcga cggaatgttt ctggcagttg gtcagtccaa
     7201 agaactgtta agtttggttc tggagagtta ccgatattat caagagtgtt taagaaacgg
     7261 tagtccatct tagtcacacg gtgacgaccg tcgttaccca taccagccat agaagttgtg
     7321 atgaatgttg ggtcacctga gtaaagggca tcgtaagctt tagtacgacc aaattttacg
     7381 gtacggagtt taaggacaaa atcatcaaca aattcttgga tttctgattc tgtaaaggta
     7441 ccgcgagcaa ggtcacgttc tgcaaagata tcaagaacga ttggcacacg tccaagagaa
     7501 gtagcagcac cgttgatcac acgacataca gccatgaaag cgatgtttac ccattggata
     7561 gcttctttaa cgttttgtgc tgggcgacga acatcaactc cgtaaaggtc accaagttta
     7621 accacttcac caagagcttg gtattgaagg ttaacttctt cgcgaagacg aatggattct
     7681 tcatcgattt cagtgatagc attccagtca ttgacttttt cttgcatcaa gtagtcagca
     7741 ccgtaaagag caagacgagc gtaaacaccg atgatacgtc cacgtgagta agcatctgga
     7801 agaccagtta cagtgtgggc atgacgagcg cgacgaatat ttgaagtata agcgcggaag
     7861 ataccgtcgt taacagttgt cacatactta gtaaagattt catgtactgc tgggtctggt
     7921 tcatagccgt tttctttaag ggtagtttcc gccatacgga taccaccttt tggcatgaag
     7981 ttcaatttga acaattcatc gttttgaata ccataaatta attcattttc tttatcgatg
     8041 aaaccagcag gaatgtcagc aattgaagtt ggacgagtat cgtatgggaa acgtgtagct
     8101 tcatagtgtg cttttgtttc ttcgataact tttttgatgt gaagtgaacg ttcagtagca
     8161 ccagccaaga aagattcatc gccatcgtat ggggtgtagt tagcttgtac aaaacgtgag
     8221 acacttgctt tttctttcca gtcagttcct ttaaagcctt cccaagcttt ttcgaaaaca
     8281 tctgtattgg ttttaacagt tgccataaat ttctccttaa attctagtaa caaagcgatc
     8341 tgttacattt acaattctaa gtttaacaca taggaaacgt tttcccaagc aaaattcttg
     8401 acaaaattaa gattctttta taatacagat tgttgaaaca gtcacaaact gtattagaat
     8461 gtattttttt tggctttaga tagcctaaaa ggtataatag agaaaggagg gacttatgct
     8521 tatttttcca ctgattaatg acacgtcacg aaaaatcatc catattgaca tggatgcctt
     8581 ttttgctgca gttgaggaaa gggataaccc tgctttaaaa ggaaagcctg ttgtgattgg
     8641 gaaagatcca agagaaacag gtggtcgcgg agttgtttcc acttgtaatt acgaagcgag
     8701 aaaatatggc attcattcgg ccatgagctc taaggaagct tatgagcgtt gtcccaaagc
     8761 catttttatt tcaggaaatt atgaaaagta tcgaacagtt ggggaccaga tccgtcgtat
     8821 ttttaagcgt tatactgatg tggtagagcc catgtccatt gatgaggcct atctagatgt
     8881 caccaacaat aagttgggta taaaatcagc cgtcaaaata gccaagctga ttcagcatga
     8941 tatctggaaa gaagtaggat tgacctgttc agcaggtgtg tcttataaca aatttttggc
     9001 taaattggct agtgattttg aaaaacctca tggcctcacc ctagtcttga aagaagatgc
     9061 cctgtgcttt ttagccaaac tccccattga aaagtttcat ggtgttggta aaaaatcagt
     9121 tgaaaaactg catgacatgg ggatttatac aggacaggat ttgttggcag ttcctgaaat
     9181 gaccttgatt gatcattttg gtcggtttgg ttttgacctt taccgtaaag cgagaggcat
     9241 cagcaattct cctgtcaagt ctgatcggat acgcaagtca attggcagtg agagaaccta
     9301 cgctaaactg ctttatcaag aaacagacat caaggcagag atcagtaaaa atgctaagcg
     9361 cgtggccgct ctcttacaag accataaaaa gttaggcaag accattgtgc tcaaagtgcg
     9421 ttatgctgat tttaccacct tgacaaaacg tgtcaccttg ccagaattaa ccagaaatgc
     9481 cgcacaaatt gagcaagtag ctggtgatat ttttgacagc ttaagcgaaa atcctgctgg
     9541 tatccgcctg ttaggggtaa ccatgaccaa tttggaggat aaggtagctg atatttcctt
     9601 ggacctatag gagaaagagt gctctatccg tccgcctcat tttggagaaa aaagaagctg
     9661 attagggatt tccctaatca gcttctttgg tccattattt tattacagca tagcttggtc
     9721 tgtatcatca cctttttcgt taagggtttt ggctttgtaa aaagcaaagc cataaagagc
     9781 agcttgtgca aggataagga tagttccaac cattgacatg gttgttgtga actggttaac
     9841 caagccgata acagaaagga taaggcctaa gatataagga atataactaa ccgttagacc
     9901 ttgttttagt ttggataagt tctgagtaca aaagatgata atggcaataa tagcaaggac
     9961 atttaagaca gataagaaaa tcataaatgg tgtcatgctg ctttgtagct gtgccaattg
    10021 ctcagttgtt aattgggccc gaaatgcttc attcttgagt tggctttgta agtagaagat
    10081 ccctgcaaat cccattaatg acagtacaac tccaagcccg tttagaataa taatggcaat
    10141 agtagacgtt ttgagtgcct gacgcacttt ttcataagaa atcatataat cctcctagag
    10201 tccttaatcc gaaattgtac aatgtgttta atacaaaaat attataccat agattaatca
    10261 aaaatgtccg tttttctagg attttttctg gaaaaagagg gcaatatctg actctgtaag
    10321 ccctatcatc gaatcgatag tcgaataatt ctcaggtgtt aacctaaaat catcattatc
    10381 tgactgagag ttctcagtgg ggttagagtt tgttgattga gaggaggcta agtcggattg
    10441 ttcttggaag cgttcgatca agtaggtttg gcgtttatcg ccttcgtgtt taatagcata
    10501 ctcaaaggca gtatattctc ccaacagaat taacttactt ttagaccgag taatggccgt
    10561 gtaaatcaca tttcgttgca agagtcggcc gctttggcgt gtgataggta aaatcaccac
    10621 ttgaaattca ctcccttgcg atttatgaat gctcatggca taggccaggg ttaattttag
    10681 ccattcattt ctagggtacg tgacttcgct gccgtcaaaa tctaagatta attcgtcttg
    10741 cttagattcg gtgtatttag caggaatcaa atctgtaata taaccaatat ctccgttaaa
    10801 gacattcaac tgagcatcgt tgactaagtg caggacttta tcacctttac gaaaatacgt
    10861 atcattgaac agaaattctg tttgtccttg caagggattg agaagttctt gcatgagttg
    10921 attaagatga ttgatgccag cttgtccttt gtacataggc gctaaaattt gaatttcctc
    10981 agcagggatg ccacttttaa tagcagatag gacaattttt tgaatcatgt cagggataaa
    11041 ggctgcttgg gcttcaaaat aagaacggtc agctttttta tcacgaaagt cagcagctaa
    11101 gattcctcga cgcatctggt ctgccaaatt gacaatagta gattcttggg attgacgaaa
    11161 tatcttttgc aaggcgattt ggggcaggct attgactttt aaaagatctg acaggacttg
    11221 accgggtcca accgaaggaa gctggtcact atctccgaca ataatcactt gagttgttga
    11281 gttaatagct cctaacaact ggttggcaag ccaggtatcc accattgaaa attcatcgac
    11341 aatcagcaag tcgcagtcta gataatcctc catggcttgg taatcgttgt cgccattgag
    11401 gcctaagtgc ctgtggatgg ttgcgctagg aagtccagtc aactcattca tgcgacgtgc
    11461 agctcgacct gttggagctg ctaacaagat aggaaggtct tttttatcca aatcaatctg
    11521 atgcaggttc gcgtaagcct gcaaaatgcc tagaataaca gttgtttttc ctgttccggg
    11581 accacctgtt aggagaaaga ccttgctggt taaggcctta gtaatggctt cttgctgcac
    11641 ttggtcatag gtgatggcaa agtctttttg aacggcttgg atggttgttt gaatggtatc
    11701 atgactaaat gactgactta aaggggtatc taagagacga gagatgttgt tagcaatccc
    11761 ttcttcagca aaataaaggc tagcatcaaa cagtttggtg tcactgtttt tgattttgcc
    11821 ctctatgatc aactcgctta gttgttcagc cacagcagca ggatcacatt ctacttgacg
    11881 tgcatcttca aggagtgtaa tggtaaagtc taataattgt cgtgcttgga cataagtatc
    11941 tcctcgattg atggattctt ccaagagaca gtgcaggagg gcagcacgaa aacgtttcgg
    12001 agagccgctt tcaatcccta agttttcagc gagagcatct gccattttaa acccaaaacc
    12061 ttgtagatct tcgactaact gatagggatt ttctttaaca aggtcaagag cctcttcttt
    12121 atacttttca aacgcttgaa aggcaaaacg gttgctaagg ccaagttcga cgagaccagc
    12181 aatcagttgc tctgtgccgt aattcaattt tagtttagcg acaaaggctt gacgattagc
    12241 cttagatagg ccagagatag tttctaattt gcttgggtct tctaaaatat ggtcaatggt
    12301 attatgacca tatagtgcaa tgattttctc cgctgttttt ttaccaatcc ccttaaaatg
    12361 gtcgctagag aaataattaa ccaaaccaga tgaactaggt ttgatttttt ggtaacggct
    12421 tagtttgagt tgctgtccat atttagggtg ctgggtcaat tctccccaaa aggtgtagtc
    12481 atctccttca ataatgtcag ccatcgttcc tgtgataatg atttcaaagt cgtcaatgtc
    12541 actgtctgta tcctcaatgg caaggaggag aatcttaaag aaattagcct ggttttcaaa
    12601 aatgatacga tcaacagtac ctgtaaaaac gtattccata gtaactcttt ctatttatac
    12661 aagataactg aaaacctgcc caaaggcagg ttttttctaa ttaaaaacgg tcattttatt
    12721 gagtggccaa aaacgagctt tcacttcacc gataaggttt tcttttttga aactaccaac
    12781 ttcgcgacta tccctggaaa caatacgatc atcaccaaga agaaggtatt ctccttttgg
    12841 aacactcatc tcaaagcgtg tttgtccctc agaattagtt gtaaaagcat cagatgtttc
    12901 tgctaactgt tggaataggg tattataggc gtaagttttt tggagtttat cgtttttaaa
    12961 ttgttttaga tactcagcca aatacggctc aactgttttt ttaccattaa tataaagtgt
    13021 gtcatcatta taagaaatgg tatcgcctgg caatccaata actcttttta cgatttcttt
    13081 cttttgtccg ttttcttctt cctgagcaac tacaatatca aagcgatcaa tcctagcttg
    13141 attaaaaacg ataaggcgtt cgccatgagc tagagttggg tccatagaat ggccgtctac
    13201 tttaacagcc tgccacaaaa aaagacgaga tagaccaaag agaattaaaa agagagtgaa
    13261 tgggccccat tctttaataa actgtttcat atgattcctt ttatttagtg agaagcgctt
    13321 gcgctttgtg agtgttggcg aagtgaagtt tagcactata ttctaagcta gacataccat
    13381 aagcggctaa gagttggcta gcaactttat ctgaagctga accagcaccg cttgggagtt
    13441 ggtaacctaa atcttgacct aattgatcga gattgtctaa aaatagattt ctagcaatga
    13501 tagagctaac agccacagcc aaatagtgac tttctgcctt ttcttgaaag gttagaggat
    13561 ttgggaaatg gtttttttcc ttttttagat gcttttcata atttgattgg ctagtgaaag
    13621 catcaataac aatttgttta ggttgaatgc ctttttgtaa caacaaaaaa atagcttggt
    13681 tatgaagagc aactttgata gaaatggcat tatatggttt acttttacca accaattcgt
    13741 tatatttttt aggtgatagg agaagtgatt gatgaggtat ttgtttctct aacagaggcg
    13801 caatctgttg aatggtttta tccgataatt ttttagaatc atcaacccca agctttttca
    13861 ggaaggaatg atctttagga tcgacaaaac ttgccacaac agcaatccca ccaaaataag
    13921 agccattacc cacctcatca ctgccgatta taggtatatc ttggctattg ttgcttgctt
    13981 caaaaactgt cttagctact ggaagattaa gctcttgagc taaagcattt gcaccgtttc
    14041 cctggagaac taattttccg gatttgtaca gcaaaacagt aaccccattt tttttagcag
    14101 caaaggctac ataggtattt tggctactga tggtgtaggg ggctaactgt ttttttaaat
    14161 gtttactcag tatagcatct attttcaaaa ctaaggtatt cataataatt attttaacat
    14221 aaaatagttg actatggtta attcataagt ttatttaaca aagaaaacag agactcgaat
    14281 gtttagacgg gttagggcaa tggtgttgac tattttacga aagtttcatt ttacggtata
    14341 atgctaatga ggtgacccta tgaaaagtat taatcgctat aaattcacct ttggtgaaaa
    14401 aacattaaca ttgacaactg acaaagacaa tctctttatg gaagaagttg agcgggtagc
    14461 taaagaaaag tatcaggctc ttaaaaatca tttaccagaa gctgatgacg agacaatcgc
    14521 tattttaatg gctatcaata ccttgtcaac acaattaagc agagagattg ccattgaaaa
    14581 aatggaagct gaaattttag atttacgtca aaaaaccttg gttggtcttc aagaaaaagc
    14641 taatcaaata gatgtgaatg aggtttaatc atgttatctt tattgatagt gcttgtttta
    14701 acttggaatt tttatattgg ttatagtaga ggtattattc ttcaatcgtt ttatgtctta
    14761 ggagccctac tttctctttt ggtagctaat cgattttata ttggattagc ccataagcta
    14821 acgctttgga ttccttattc taacccggta gaaggaacat cagtcttttt ctttaaatca
    14881 gttgatatct ttgttttaga taaggtttat tatgcaggcc ttgccttttt tatcattttc
    14941 ttattggggt atacattgag tcgctttctt gggatttttg ttcatttcct tttgctagat
    15001 tattttgata accagtggac aaaatgtttg agtggcggac tagcgcttct agtatcgctt
    15061 ctttttttga acatgttact gtctattttt gcaacggtcc ctatgccttt tttacagcac
    15121 tatttgcact ctagttttct tgctcgtttg gtgattgaac accttccacc attgacaata
    15181 attattcaaa aattgtggat tcaagccatt atttgatatc gttttgtgac taatataaga
    15241 acctggagtg agtttcacct ttaggttctt tatttacgag aaactgttta gaaataaaga
    15301 gaacgcatgg gaacttagtg actttcttgc cccattttcc atcattttag gtataatgaa
    15361 gagtatgaat aacaagattt tagaacagtt agaatttaac aaagttaagg aattgctatt
    15421 accttatctc aagacagaac aatcacaaga agaattatca gagctggagc cgatgacgga
    15481 ggctcctaaa atagaaaaaa gttttaatga aatttctgac atggaacaga tttttgttga
    15541 acatcactca tttggcatag tcagcctaag ttcaatctct gagagtttaa aacgcttaga
    15601 gctttcagct gatcttaata ttcaagaact tttggctatc aaaaaagttt tacagagttc
    15661 ttcggatatg attcactttt attctgattt ggataatgtt tctttccaat ctttggatcg
    15721 tttgtttgaa aatttggaac aattccctaa tctgcaaggg tcttttcaag ctatcaatga
    15781 tggtggtttt ttagaacatt ttgcgagtcc agaattagag cgtatccgtc gtcaattaac
    15841 aaacagtgaa cgacgggttc gtcagatttt acaggatatg cttaaggaaa aagcagagct
    15901 tttatcagag aatctaatcg ctagtcgtag tggacgaagt gtcctaccag taaaaaatac
    15961 ttatcggaat cgtatttctg gtgtggttca tgacatctct tcttcaggaa gtactgttta
    16021 tattgagcct cgtgctgtag ttacactaaa cgaagagata acgcagctta gagctgacga
    16081 acgtcatgaa gaaagtcgta ttttacacgc attttcagac ttgttaagac cccatgtcgc
    16141 cactattaga aataatgcat ggattcttgg gcatcttgat tttgtaaggg ctaaatatct
    16201 ttttatgtct gataataagg cgacgatacc tgagatttct aatgacagca cgttagcatt
    16261 aatcaatgtt cgtcatcctc tgttaagtaa ccctgtggct aatgacttac attttgatca
    16321 agatttaact gcaattgtca tcactggtcc caatactggt ggtaagacga ttatgctaaa
    16381 aacactcggt ttagcacaat taatgggaca gtctggtttg ccagtattag cggataaagg
    16441 tagtaaaatt gcagtattta acaatatctt tgcagatatt ggcgatgagc aatctattga
    16501 acaaagtcta tcaacttttt ctagtcatat gacgcatata gtcagtattt taaacgaggc
    16561 tgaccacaat agtttagttc tcttcgatga actgggagca ggaacggatc ctcaagaagg
    16621 tgctagtttg gctatggcta ttttagaaca ccttaggtta agtaatatca aaacgatggc
    16681 gaccacgcac tatccagaat taaaagctta tgggattgag acaaattttg tagagaatgc
    16741 gagcatggaa tttgatgccg aaacgcttag ccctacgtat cgctttatgc aaggagttcc
    16801 tggacgatca aatgcatttg aaattgcttc tcgccttggt ttagctccat ttattgttaa
    16861 acaagctaag cagatgacag attctgactc agatgttaac cgtattattg aacagttaga
    16921 ggcacagaca cttgagacac gtagaagact ggatcatatt aaagaagttg aacaagaaaa
    16981 cctcaaattc aatcgtgcgg ttaagaaact ctataatgaa ttttcacatg agcgcgataa
    17041 agagttagaa aaaatctatc aagaagctca agaaattgta gatatggctt tgaatgagag
    17101 tgatactatc ttaaaaaaac tcaatgataa gagtcaatta aaacctcacg aaattataga
    17161 tgctaaggca caaataaaaa aattagcacc tcaagttgat ttatcaaaaa ataaagtctt
    17221 aaataaggct aaaaaaatca aagcagctcg tgcccctaga attggtgatg atattatagt
    17281 gactagttat ggacagcgag gtaccttaac tagtcaatta aaagatggcc gttgggaagc
    17341 acaagtggga attatcaaaa tgacattaac acaagatgaa tttagcctcg ttagagtcca
    17401 agaagaacag aaagtcaaaa ataaacagat taatgtggtt aaaaaggctg atagttctgg
    17461 accaagagct cgacttgatc ttagaggtaa aagatacgaa gaagcaatgc aagagttaga
    17521 tcattttatt gatcaagcat tgcttaacaa tatgggacaa gttgatatca ttcatggtat
    17581 tggtacaggc gttattcgtg agggagtgac aaaatatctt cgtcgtcata agcatgttaa
    17641 gcattttgct tatgccccac aaaatgcagg gggatctggt gccacaattg taacgttagg
    17701 gtaaatgatg gaatcatatg aacactttta tgccaaacta tctcaacctt ttagaaaaac
    17761 cccacagtta ataattcttt taaatgtttt actaaaaata atcacaggag tgatgtacat
    17821 actttatcca tcttttctga tatttacgtt ttggcaaggg atgacatttc aattatggtt
    17881 aaggctatta attattcctg ctgttggctt tatagctttg tcttatatta ggaaacgctt
    17941 tgattttcca cgaccgtatg aaaaatggaa tattaaacct ttaattgata aggatacaaa
    18001 gggaaggtca atgcctagca gacatgtttt ttcagctacg atgattagta tgtgtttgtt
    18061 acgatattat gtttactttg gaatagtttg tttaatatta tcggctttat tggcaatttg
    18121 ccgtgtgata gcaggtattc actatcctaa ggatgttatt gtaggttacc ttattggctt
    18181 gatgttaggg ctttgtttat tgatttagcg agttcgtagc aaatagtttc aaaaacaact
    18241 aaattcttgt acaataggct tatcattaag atgaaatgga gaaaaaagat ggcattagaa
    18301 gtaacagatg ctacatttgt agaagaaact aaagaaggtt tagtactcat tgatttttgg
    18361 gcaacttggt gtggtccatg tcgtatgcaa gcaccaatct tagaacagtt atctcaagaa
    18421 atcgatgaag atgaactcaa aattttgaaa atggatgttg atgaaaatcc ggaaactgct
    18481 cgtcagtttg gtattatgtc aattccaaca ttgatgttta aaaaagacgg agaagtggtt
    18541 aaacaagttg caggtgttca tactaaagac caactgaaag ctattattgc tgaattgagt
    18601 taactaaaat aaagcccagc gtcacgctga gctttatttt atgacctact aacttcaatg
    18661 gaataaccat gtaaacataa aacgacttgc aaaagcaaaa gcaacagtaa tgaggaaaaa
    18721 tacagtgaca ataaggggtt tctgataagg aagttttgct ctttcttctc gtttttcgat
    18781 ttcgtctaat aattttccat ttgaaacagc taggatttcc ttataaggtt gcacatcata
    18841 ttttttctta aaacgttcca cacgattagc ataagtcata gtaattatcg ataataaaac
    18901 aaaaatgcca agtcctagcc actctaagaa atagactaat ggataacttg aaatcattaa
    18961 tagtatcatc aatgttacca ttactttggt atctcgttta aaattctttt tatcaacctg
    19021 agtgatggta tatttcattt tctcaatgtc tcctttaatg agttggtcta agctcacttg
    19081 aaaaatttga cttaggagta agaggctatg gatgtctggg taagttttgt cattttccca
    19141 gttagatatg ctctgacagc ttacatagac tttctcggct aatttttctt gcgagagcgc
    19201 ttgttgttta cggtagcgaa taatttgctg accaatttcc ataaatatca ccggaaaact
    19261 ttacagcggc gtaaaggaat tgtaaacaaa aagtgaaccg ttatagttca cttgcgatta
    19321 agcatttttc tgttttaagt aggtctctag cattttcttt tgtggtgttg caaagggata
    19381 cagagaaaag tcctcaattg ctacccactt taggtgagga gcattaggta aatctgttgc
    19441 tttgaccacc ccctctatga gttctattgt ccacttctgg tgactaaaag tgtgcttaat
    19501 atttggaaag tgattatcag tccattgggg ctttaattga tattctcttt cgaaagtttc
    19561 attttgggtt tgccagatta tggggttgga ttgattgtca tcaaataaat ctaattgttg
    19621 agaaagaggt gacgtttcga taataggaaa tgaccaaaac cctcctagaa gtctcccttt
    19681 agtatttttc tccagtagat attgtccatt ttggttacga atgacaaaag cctgaattcg
    19741 cattggttta ggctttttct ttggattttt tatggggtat ttaccataag taccattcaa
    19801 ataagcagcg ttaaagaaac gaatagggct ttcatcaggc ctaggtgtct tagcggattc
    19861 gatgtctgta cctagatcca taagtgcctg gttaaaatca ccgggtctgt cagggtcaat
    19921 tagtatttcc ataatagctt gaaaaatttt acgattttta gggtcaccga tatcataatt
    19981 aacttcaaac aaacgagcca tgacacgcat cacattgcca tcaacagcag gctctggtaa
    20041 gttgaatgag atgctggcga tagcacctgc agtataagga ccaatccctt ttaatgaagc
    20101 aatatcatca taagtgtgag gaaatatgcc accaaaatca accatcactt gctgtgcagc
    20161 cttttgcata ttacgcaccc gagaataata gcctagtccc tcccatgcct ttagtaattg
    20221 ttcttcagga gcgtctgcca aatcttttat ttgaggaaac cactctagaa aacgtttata
    20281 ataagggatt accgtattaa cttgtgtttg ttgcaacatg atttcagaaa cccaaatata
    20341 gtatggatta gtagttcttc gccaagggag atcacgtttt tcttggtcat accaccctaa
    20401 aagtgtgcga cgaaaagaag cgattgtctc attatcccac atattaatac cataatcttt
    20461 taattcaatc atgttgttat tgtaacacag gagtcttaaa aagagtaaaa aaagatttta
    20521 ggt
//
LOCUS       DAUNLR010000029        19943 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUNLR010000029 DAUNLR010000000
VERSION     DAUNLR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19943
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.029"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            161..955
                     /locus_tag="VLL59_001113"
     CDS             161..955
                     /locus_tag="VLL59_001113"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HER6509241.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGVAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            980..1621
                     /locus_tag="VLL59_001114"
     CDS             980..1621
                     /locus_tag="VLL59_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HER6509242.1"
                     /translation="MKIALINENSQAAKNGIIYDALTSVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVAYLKSVLGQ"
     gene            1650..2651
                     /locus_tag="VLL59_001115"
     CDS             1650..2651
                     /locus_tag="VLL59_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HER6509243.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGIRHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADATMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLANQRDVQR"
     gene            2656..3291
                     /locus_tag="VLL59_001116"
     CDS             2656..3291
                     /locus_tag="VLL59_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HER6509244.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            3588..4238
                     /locus_tag="VLL59_001117"
     CDS             3588..4238
                     /locus_tag="VLL59_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HER6509245.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            4934..6058
                     /gene="queG"
                     /locus_tag="VLL59_001118"
     CDS             4934..6058
                     /gene="queG"
                     /locus_tag="VLL59_001118"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HER6509246.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRISPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPNSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNPPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNSIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF"
     gene            6127..7225
                     /gene="prfB"
                     /locus_tag="VLL59_001119"
     CDS             join(6127..6198,6200..7225)
                     /gene="prfB"
                     /locus_tag="VLL59_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HER6509247.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTDPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            7244..7936
                     /gene="ftsE"
                     /locus_tag="VLL59_001120"
     CDS             7244..7936
                     /gene="ftsE"
                     /locus_tag="VLL59_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HER6509248.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            7929..8858
                     /locus_tag="VLL59_001121"
     CDS             7929..8858
                     /locus_tag="VLL59_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509249.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(9168..9866)
                     /locus_tag="VLL59_001122"
     CDS             complement(9168..9866)
                     /locus_tag="VLL59_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HER6509250.1"
                     /translation="MPFIFRHSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            10034..10799
                     /locus_tag="VLL59_001123"
                     /pseudo
     CDS             10034..10799
                     /locus_tag="VLL59_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
     gene            10907..13408
                     /locus_tag="VLL59_001124"
     CDS             10907..13408
                     /locus_tag="VLL59_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HER6509251.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFAR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETGCFLI"
     gene            13743..14936
                     /locus_tag="VLL59_001125"
     CDS             13743..14936
                     /locus_tag="VLL59_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HER6509252.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            14957..16303
                     /gene="asnS"
                     /locus_tag="VLL59_001126"
     CDS             14957..16303
                     /gene="asnS"
                     /locus_tag="VLL59_001126"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HER6509253.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKLAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            16717..17607
                     /gene="rapZ"
                     /locus_tag="VLL59_001127"
     CDS             16717..17607
                     /gene="rapZ"
                     /locus_tag="VLL59_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HER6509254.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            17604..18581
                     /locus_tag="VLL59_001128"
     CDS             17604..18581
                     /locus_tag="VLL59_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HER6509255.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNENDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            18578..19489
                     /gene="whiA"
                     /locus_tag="VLL59_001129"
     CDS             18578..19489
                     /gene="whiA"
                     /locus_tag="VLL59_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HER6509256.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
BASE COUNT         6157 a         3394 c         4252 g         6140 t
ORIGIN      
        1 tattaagtat aggacaagac taaacaagaa tgacagtttg gataagagca ctcttttaaa
       61 ttttgaaccg ttttcattaa aatgattgac aaaactagtt tactttgtta tagtcttggt
      121 aaacaggttt acttaatctg ataacaaaaa ggagaatcct atggaaaata tgttttcgtt
      181 acaaggtaag attgccttga ttaccggagc atcttacggt attggttttg aaattgccaa
      241 agcctatgct caagcgggtg caactattgt gtttaatgac atcaaacaag agttagttga
      301 taagggggtg gctgcctatc gagagttagg gatagaagcg catggctatg tttgtgacgt
      361 gactgatgaa gctggtatcc aacagatggt tagtcaaatt gaagatgaag taggtgttat
      421 tgatattctg gtcaacaatg caggtattat taggcgtacg ccgatgcttg aaatggccgc
      481 agaagatttt cgtcaagtta ttgatattga tttaaatgct ccttttattg tgtcaaaagc
      541 tgtattacca tcaatgattg caaagggaca tggtaaaatt ataaatatct gttctatgat
      601 gagcgaattg gggcgtgaaa cagttagtgc ctacgcggcg gctaaaggtg gcttgaaaat
      661 gttaaccaaa aatatagcct ctgagtttgg agaagccaac attcaatgta atgggattgg
      721 tcctggctac attgcgacac cccaaacagc tccgttgaga gagcgacaag cagatggtag
      781 tcgtcatcct tttgatcaat ttatcattgc taaaacacca gcagcacgtt gggggacaac
      841 agaagactta gctggtccag ctgtttttct agctagcgat gccagtaatt ttgtcaacgg
      901 ccatattctt tatgtcgacg gtggcatttt agcttatatt ggaaaacaac cttaatcaca
      961 cactagaaag agattttata tgaaaattgc attaattaat gaaaatagcc aagcggctaa
     1021 aaatggtatt atttacgatg cccttacctc agtgacagat aaacacggct accaagtctt
     1081 taactatggc atgtatggca cagaaggtga aagccagttg acctatgttc aaaatggact
     1141 cttagcttct attttattga ccactaaggc ggccgatttt gtggtgactg gttgtgggac
     1201 aggtgtggga gctatgttgg ccttgaacag cttcccagga gttacctgtg gttttgcgag
     1261 tgagccaaca gaagcatatc tcttttctca aatcaatggt ggtaatgcct tgtccattcc
     1321 ttttgccaaa ggttttggtt ggggagcaga gttgaatttg accttaatat ttgaacgcct
     1381 ctttgcagaa ccaatgggtg gcggttaccc taaagagcga gctattcctg aacagcggaa
     1441 tgcacgtatt ttaagtgatc tgaaaaaaat tacttacaga gatttgttgg caattgtcaa
     1501 agacatcgac caagatttcc tcaaagaaac gatttctggc gctcatttta aagagtactt
     1561 ctttgccaat gcggagccgt cagaattagt cgcttatttg aaatcagtac ttggacagta
     1621 attccatttt gacgaggaaa ggaggtcaca tgtctaagtt attattggtt ggtgaaccgc
     1681 tgattcgcgt tagccccaat cagtttcagc ctttgaccaa tgcctgcgac gctcagcttt
     1741 ttttcggcgg ttcagaagtt aatattgcaa gaactctagg cggttttggc ttagaagcaa
     1801 ggctatttac ggccctacca gataatcctg ttggtcacgc ttttcatcag tttttgaagc
     1861 aaagcggcgt ggatatgtcc ttgacggctt ggcaaggtca tcgcgttggg ctatattacc
     1921 ttgaaaatgg ctttggctgt cgggctagtc aggtttatta tgaccgctgt ggctctagct
     1981 tttcggcctt agataaggat agtcttgatt tagctgccat ttttgaaggc attcgtcact
     2041 ttcattttag tgggatcagt ttggcgctgg gcaaaaaaac tcaggacctg attgaggtac
     2101 ttgtgagaga agctaagaaa agggatattt gtgtttcttt tgatcttaac tttagatcta
     2161 gtatgattgc ggtagctgat gctaaacgac tcttttctca ctttgctcaa tacgcggata
     2221 ttatttttgg catggaacct ttgctgttag atagtgacga ttttgacatg tttgatagga
     2281 ataaggcaga tgctacgatg attagagaac gtctggcagg actttatcag cgctatcagt
     2341 tacaagctat ttaccatacg gagcgttcaa atgatgccca aggcagtaat cgtttcaagg
     2401 cttatgccta tgatgggcag ttttacgaat cctgtgaagt gacgacccca gtcttgcaac
     2461 gggttggaag tggagatgct tttgtggcgg gtttacttta tcagttgtta gaaggtaacg
     2521 aaaagcagcg caaccttgat tttgctgtgg caacagctag cctaaaatgt acagtagctg
     2581 aagatcagct ctatcacagc gtccaacaag tagaagcagt cttagctaat caacgagatg
     2641 tccagaggtg atgatatggg aaaaatagaa atcttaacca aacttaaggc taatcggctt
     2701 gtcctggttg tacgaggaga gtctagtgag gaagctttag cttgcagcct ggccagtatt
     2761 gaaggtggca ttaagacaat tgaagtcacc tatactaacc cctttgctag tgaggttatc
     2821 ggtcaattag ctgaacgctt caaagaagat cctgaggtat tgataggtgc tgggacagtt
     2881 ttggatgatg tcactgcccg ccaagctatt ttagcaggag cacagtttat tgttggtcct
     2941 aatttcaatc gagcagtggc tttgatttgt catcgttata gcatacctta tttaccaggt
     3001 tgtatgacgg ttaatgaagt ggttacagca ttagaatcag gggttgatat ggtcaaaatt
     3061 tttcctggtt ctactgtagg gatatccttt attcgggcaa tcaaatctcc tttgccacaa
     3121 gtagaggtta tggttacagg cggagtttct tcagataatc tcaaagactg gctagctgct
     3181 ggagtagatg ttctaggcat aggaggcgag tttaatcagt tagcgagcca aaaacaatat
     3241 aacctaatca ctaagaaagc cgctcattat atcaaaagtt tgcgacaata atctaaaaaa
     3301 cgtttttacc ttggctttag tgctagtaaa aacgtttttt tatcattcat tcaattaata
     3361 tgcttctgct catgtttttc cagatagtat agatataaga gcagctaatt taacaagatg
     3421 agcctgttgt ttgatatata ggatataaac tttttatgat caaacaaaag taataccttt
     3481 tgaattcgtt agtattgatc tgatctaaag tgatatcact tagaacggac tagctgtaca
     3541 gcttttacag caacttatgc taaaatagaa aaaaaggaga aatgttgatg attaaaggaa
     3601 ttatttttga tatggatggt gttttatttg atacagaacc tttttatctg aggcgacgag
     3661 aagatttttt taagacaaag ggaattccca ttgatcactt gaactctaaa gattttattg
     3721 ggggcaatct ccaagaatta tggaaagagt tgttaggtaa aaatagggat gatgctatcg
     3781 ttaaggcaat tacaactgac tatgacgctt acaaacaagc gcataagcct ccttatcaaa
     3841 aactgttgat tacagaagtg aactcttgtc ttgaacagtt gaaaaaacaa ggtatcaaac
     3901 tggctgtggc atcaaactcg aagcgtcagg atgttttgtt ggcgttggag acaacgcaaa
     3961 taaaagatta ttttgaaata atcctagcgc gtgaagatgt ttctagaggc aaaccttatc
     4021 cagatattta taataaagca gtacaaaaac taggattaca aaaaaaacaa ctgcttgtag
     4081 tagaagacag ccaaaaaggc attgctgccg ccaaagcagc caatctgaca gtttttgcca
     4141 ttaccgacta ccgatatggc attgatcaga gtcaagctga tcacaagata gatcatttag
     4201 gacaactgtg tgtaaaaatc ggttgttttg gatcgtgaag taacgcaact aactgatcat
     4261 tgatgatact tcaagacact taagaatacg tctaggactt tctacagacc aataacaaga
     4321 atacgtttat gtgtttttac tgttttttag ctacctattt acaatatgac actgaaaaga
     4381 gtactatgtt taagttatta tcaaaaaaac cgtcgcataa gatcacctag aaaagaatta
     4441 tgatttttgt gatttggatg cgatcgttag tcgttgacca tctttatgtg gcaggagata
     4501 tgtttaaccg tggtcattat ttggatttgt ttttagatta gctagtgagt aaatatagaa
     4561 ggatcataat actgctttga caaaggcagt atctgagtcc atgagttgca cggataatgt
     4621 gactcggttt tggttaggta taataatatt tggaagtgtt atgctgcttg tcttcgtagg
     4681 tccattgatt atagtcagac ttactttaga gctgagctga ctgtctagac aagacgtgat
     4741 ggagatgtga tttctgacca agtagaggta accagaaaag ggacttttac gatgtaattg
     4801 aatttacttg ttgcattctt gtgcatgtta agagagaaaa cccagataaa tcaggaagta
     4861 aaatggttat gtttgattag aattgtcctt ctttttcctt gaagtcttaa cttattttga
     4921 ttatgatagt agtatgacta ttaaggcaga aattaaggca ctcgccaaag aaattggtat
     4981 ctctaaaatt ggttttacga cggcagataa ctttgattat ttggaaaagt cattgcgtgc
     5041 ttctgtggaa gaggggcgca attcaggatt tgaacacaaa gtcatagagg atcgtatctc
     5101 ccctgaaagg cttttagaat cggctaaaac gattatttca attggcgttg cttatcctca
     5161 caaacttcct cagcaacctc aaaaaacacc ttataaacga ggaaaaatta cacctaattc
     5221 gtgggggctt gattatcatt atgtggtcgg cgaaaagtta gatagactat caaaaggcat
     5281 tgaagagctc tgtcgagatt ttcctttgca acaaaaagca atggtcgata ctggagcttt
     5341 agttgatact gcagttgccc aaagagcggg tattggtttt ataggaaaaa atggtctagt
     5401 tatttctaaa gaatatggct cttatatgtt tttgggagaa ttaattacca atttagagat
     5461 cgagccagac aagcctgtcg attatgattg tggtgactgt cgtcgttgtc tagatgcctg
     5521 tccaacttct tgtttaattg gtgatggctc aatgaatgcc aagcgttgtc tatcatttca
     5581 aacccaagat aagggaatga tggacataga gtttcgaaaa aagattaaaa cagttatcta
     5641 tggttgtgat atttgccaaa tttgctgtcc ttataacaaa ggtataaata atccaccagc
     5701 tacagagatt gatcctgagt tggctcaacc agaattaata ccatttttga gtttatcaaa
     5761 tggacaattt aaagaaaaat ttggtatgat tgctggaagt tggcgaggta aaaatatttt
     5821 acagcgtaat gccattattg cgctagcaaa tgctcatgat aaaactgcag tggtcaaatt
     5881 aatagagatt attgataaaa ataataactc tattcatact gcaacagcta tatgggcatt
     5941 gggagaaatt gtcaaaaaac caaacgatga gatactggcg tttatgagtc atttaacctt
     6001 aaaagatgaa gatagccgaa aagagttgga attaatccgt cataaatggc aattttaagc
     6061 cttttatggt atttttaaga accttatgat aaaataaaac agattaacaa agattggaga
     6121 aatctcatgg aagtggctga aattcgccaa aaaatagtag aaaataaaga gaagttgact
     6181 agcttcagga ggtctctttg acttagatcg tttggaagag gagattgctc ttcttgaaaa
     6241 tcacatgact gatccagact tttggaatga caatattgca gcgcaaaaga catctcaaga
     6301 actgaatgag ttaaaaggta agtatgatac tttccataat atgcaagaat tatctgacga
     6361 aacagaactc ttacttgaga tgcttgacga agatgattct ttgaaagaag aattagaaga
     6421 aaatctaatg cagctagata agataatggg tgcttatgaa atgacgcttc tcttatctga
     6481 accctatgac cacaataatg ctatcttaga aatccatcct ggttcaggag gaactgaagc
     6541 gcaagattgg ggagatttac tcttacgaat gtatacccgt tttggcaatg ctaatggttt
     6601 taaagtagaa gtattggatt atcaagcagg ggatgaagct ggtattaaat cggttaccct
     6661 ctcttttgaa ggtcctaatg cttatggttt gttgaaatca gaaatgggag ttcatcgcct
     6721 cgttcgtata tcaccttttg attcggctaa acgtcgtcat acctcatttg cttcagttga
     6781 agtgatgcca gagttagatg atacgattga agtagaagta cgtgatgatg acattaaaat
     6841 ggatactttc cgttccggag gagctggtgg tcagaatgtc aataaagtat caacaggtgt
     6901 tcgtttgacg catattccaa ctggaattgt ggtatcgtct accgttgacc gtactcaata
     6961 tgggaaccgc gatcgcgcta tgaagatgtt gcaggctaag ctatatcagt tagaacaaga
     7021 aaagaaagca caagaagtag atgctctcaa gggtgataaa aaagaaatca cttggggaag
     7081 tcagattcgt tcttatgttt tcacccctta tacgatggtg aaggatcatc gtactaactt
     7141 tgagcttgct caggtagata aggttatgga tggagaaatc aatggcttta ttgatgccta
     7201 ccttaagtgg cgcattgaag actaaaaata ataaaggaga aacatggcac taatagaaat
     7261 gtctggtgtt actaaaaaat accgccgctc aacgaccgcc ctcagagacg tcaatgtttc
     7321 tgttaaccaa ggtgagtttg tttatctcgt aggcccatca ggtgctggta aatcaacttt
     7381 tatcaaactc ctttaccgtg aagaacaact gacaactggt aagctatatg tgggtgaatt
     7441 caatttaact aaactaaaag cacgtgatgt tccgattctt cgtcgtcaca tcggagtagt
     7501 ttttcaagat tacaaactgc taccaagaaa aacagtcttt gaaaatgtag cttacgccat
     7561 ggaagttatt ggtgaaaagc gccgtcacat taaaaaacgc gtgccagagg tactcgattt
     7621 agttggcttg aaacataaga tgcgttcttt tccaagtcag ctatcaggag gggagcagca
     7681 acgtgtggcc attgcgcgtg cgattgttaa caaccctaaa ttattgattg cagatgaacc
     7741 gacagggaat ttagatcctg agatttcatg ggaaattatg cagttacttg aacgtattaa
     7801 tgttcaggga acaactatct taatggcgac acacaacagt catattgtga atacatttcg
     7861 tcatcgtgtt gttgctattg aagatggtcg catagtacgt gatgaagaaa aaggagatta
     7921 tggttacgat gattagatac tttttccgtc atatttggga atccattaaa aatcttaaac
     7981 gcaacttttg gatgacattt gcttcagtta gtatggtggc tgttacattg actttagttg
     8041 gtgtttttgc ggcgacattg ttgaatatac agcgtgttgc ttcgggtgtt gaaaataatg
     8101 tccatatcaa tacctactta caagttgatt caactgatgc tgcaaaagtt attcaaaata
     8161 ctgccggtga acctgttaat aacgataact accacagtgt ttacgacaaa attgctcaga
     8221 taaaaggtgt caaaaagatt acattttcta gcaaggatga acaattgaaa aaattgcaag
     8281 aaaccttagg tgatgtttgg aatatgtatg accaagacac taatccgctc caagatatct
     8341 atcttattga gacccagacg cctaaacaag ttaaggcgat cactaaaaag atcagaacga
     8401 ttgaaggcgt agaagccgca gattatggag ggattaactc cgataaacta tttaagtttt
     8461 caacattaat tcaaacttgg gggctgatcg gaacagcaat gctattattt gtagctgtct
     8521 ttctcatttc aaacactatt cgtatgacta ttatgtctcg taaacgcgac attgaaatta
     8581 tgcggttagt tggtgctaaa aattcttata ttcgagggcc tttctttttt gaaggggctt
     8641 gggttggctt gttaggagct gttttaccat ctcttctgat ttattatgga tatgatcttg
     8701 tttataagca ttttgcacaa gaattacaac gtaataatct ctcgatgtat ccgcttgatc
     8761 cttatgtata ttacctgatt ggtgctttgt ttgtcatagg tattatgatt ggttcgcttg
     8821 gttcagtgct ttctatgaga cgttatttaa aattctaaaa aaagcgctgc tgacgaaacg
     8881 tagcgacctt caaaagttgg acctcttatg ttattccaag gacctcgttt tgtattgcac
     8941 aggactggtc cttttcattt tgttttgatt catttgttta tttgtaatag gtaatacagt
     9001 ttaaaatagc agtttctaag gtttcaagag aagaaaagca ccccaaaagt tagatgtttg
     9061 atgtatctaa cttttggggt gttattcaaa atttagtggc tcttttttag taaaatacta
     9121 tgatttcagt tttaggataa cctcaaacag tatctaaaat agctatgtca atgaaaaaag
     9181 gggttagcat ttttttcgtg acaaatggta gtagaaggac catgcccagg ataaactcgg
     9241 taatgattag gtaaggtgaa tagttcttgg cgaataccag taatgaggtc ctcaaagtta
     9301 ctggtaggta agtcagtacg accgatagtt tcacgaaata gagcatcgcc agtaacgact
     9361 aattcatctg agtggaaaac aaatgagact cctccccaag aatgaccagg tgttggtaaa
     9421 actgtgaatt caaaaccatt tagttgatag ggttgcttta atttaaaaaa gttctctgcc
     9481 ggtcttgcta taacagtaat gatatcatca tgacggccta aaccagataa attatcatct
     9541 ggggaagata gccaagcggc ttctttttct gaaacataaa caggtggatg atcaaaagca
     9601 tctctgacca aatctaaact aaaaatatga tcatagtgag tatgcgttaa gaggatagcc
     9661 actaaaggtt tttcaaagga tttaatttta gcaatgattt cttggccgtt acttcctgga
     9721 tcaatgagga taacagcttg atcattaacg aggtaataag tattttcacc agcaatgtgg
     9781 tttattgttt tatagatttt cataaggata gtgtaccaaa aaatcaaggc tttgttaaaa
     9841 aaagagtggc ggaaaataaa tggcaattag tttcagaaaa tatgagatct cacagcaatt
     9901 tcttgacacc gttttcataa aggtgtatca taaaagtaat caataagcca agcctaaagc
     9961 tgaacttagt ttaagaacac tgactttttg agagcaacct aatcggttga ctaaaaaata
    10021 tgaggtggaa gatatgtcaa aagttgctat tgttactggt gctggtcaag gaattggatt
    10081 tgctatttta aagccgtctt catgcagacg gctttaaaat aggcatttta gactataatg
    10141 aagagactgc tcaggctgcg gttgataaac tatcacctga ggatgctgtt gcagttgtag
    10201 cagatgtttc aaaacgtgac caagtttttg atgctttcca aaaagttgta gatacttttg
    10261 gtaattttaa tgttgttgtt aacaatgcag gcgttgcccc aacaacccct cttgacacga
    10321 ttactgaaga gcagtttgaa aaggcttttg caatcaatgt cggaggaacg atttggggaa
    10381 gccaagcagc tcaaaaacat tttagagaat taggtcatgg cggaaaaatt ataaatgcaa
    10441 cgtcacaagc aggatgtgaa gggaatccta atttgactgt ttacggtggt acaaaatttg
    10501 cagttcgtgg tattacacag actttggcaa aggatttggc atcagaagga atcacagtca
    10561 atgcttacgc accaggtatt gttaaaacac ctatgatgtt tgatattgcc catgaagttg
    10621 gtaaaaatgc aggcaaagat gatgaatggg gtatggagca atttgcaaaa gatatcactt
    10681 tgaaacgctt gtctgaacca gaagatgttg ctaatgcagt aggcttctta gcgggagatg
    10741 attcaaatta tatcactgga caaacaatag ttgtcgatgg tggtatggta ttccattaaa
    10801 aatgattaat actgacactg tgggtttcac tcacagtgtt ttttaagaag tataaaaaat
    10861 tatcctatct tggttattgg agtgatggca cctttgaggt atagtcatgt tttgttttat
    10921 agatatagcg tgctataata gacttactat gacccagaaa aaacttagaa aatatgcagt
    10981 agttgacttg gaggctactg gagcaggtcc caatgcttct attattcagg ttgggattgt
    11041 tattatccaa ggaaataaaa ttattgatag ttatgaaaca gatgttaatc ctcatgaatc
    11101 tttggatgag catattgttc atttgacagg tattacggat aagcagttgg ctaaagctcc
    11161 ggattttggt caagtggcgc atcacattta tcaattgatt gaagattgta tttttgttgc
    11221 ccacaatgta aagttcgatg caaatttatt ggcagaagct ctttttttag aaggatatga
    11281 gttaacaata ccacgtgttg atactgttga attagcccaa ctatttttcc ctcgctttga
    11341 aaagtataac cttagtcacc tatctaggca gctcaatatt gatttggcag aagctcatac
    11401 tgctattgca gatgcaagag ctacagctat actgttttta agacttttac aaaaaattga
    11461 gagccttcca attgagtgct tagaaagctt attagtctat tcagatagcc tgctatttga
    11521 aacagcaatg gtcattcaag aaggattagc caaagccaaa ccttatgatc ccaacaaata
    11581 cattaaaatc agacagattc tcttaccaaa gggctcaaaa gctctcaagc cttatcaaat
    11641 atcaaaaagc ttccctatta atatggcact attaggtctg gaagaaaggc ctaaacagac
    11701 tcaatttgct cagttaattg acgaagatta ccatcaggga gtagctagtt ttattgaagc
    11761 tcagacaggt attggaaaaa cctacggcta cctgctaccc cttttggcaa aagaagatca
    11821 aaaccaaatc attgtcagtg tgcccaccaa acttcttcaa gaccaattaa tggctggtga
    11881 agtagctgct attcaagaac aatttcacat cgcctgccat agtttaaaag ggcccgccaa
    11941 ttacctaaag ctagatagct ttgcagatag tttggaccaa aatgaccaga accgtttggt
    12001 gaatcgttat aaaatgcaat tattggtttg gctcttagaa actaagacag gagaccttga
    12061 cgaaatcaaa caaaagcagc gctttgcagc ttattttgag cagcttaagc acgatggaga
    12121 cattaagcag tcttctgaat tttacgatta cgatttttgg agagttagtt atgaaaaagc
    12181 caaaacagcc cgtctcctga ttaccaacca tgcttatttt ttacaccgtg ttcaagatga
    12241 caaggacttt gctagaaaca aggtcttggt ctttgatgag gcccaaaagc tgatgctcca
    12301 attagatcaa ttatcacgtc atcagcttaa cctgacggtt tttttacaaa caatacaggc
    12361 caagttaagc aaccctttac ctcttttaga aaaacgctta ttggaaagct tgtcgtttga
    12421 actgggacaa gtgtcaagtg attactatca aaataaagag caccagcttg ctcatgattg
    12481 gtctcgtata gctggctacg ccaaagaatt aacaggagca gattatcaag agttacaagc
    12541 cttttttgct acctcagatg gtgactactg gcttagtagc gaaaagcaag aggagaagcg
    12601 agtgacttat ctaaacagtg ctagtaaggc atttattcat ttccaacagc tcttaccaga
    12661 aacggtgaaa acttattttg tttctgccac tttaaccatc agctcagaag taaccttggc
    12721 agacctatta ggttttgaag agtatctcta tcatgtcatt gaaaaggata aaaagcaaga
    12781 ccagttggtg cttgttgatc aagaggcgcc tatcgtgaca gaagtcagtg accaaatcta
    12841 tgtggaagca attgcaaaac gaatcgaaag cttgaagcaa gagggttatc ctattttagt
    12901 gctttttaat tctaaaaaac acttgctgtt ggtttcagac tatctagacc aatggcaggt
    12961 gcctcactta gcgcaggaaa agaatggaac agcttataat attaaaaaac ggtttgatca
    13021 aggagagcaa actattttgc ttggtttagg ttctttttgg gaaggagttg attttattca
    13081 agcggatcgt atgattaccc ttatcgcacg attgcccttt gataacccag aggatttctt
    13141 tgttaagaaa atgagtcatt atctattgga aaaaggtaaa aatcctttca gagattactt
    13201 cttgccaatg actattttgc gattaaaaca ggctattggt cgcacgatgc gtcgacaaga
    13261 tcaaaagtca gtggttatta ttttggatcg tcgtctcctt acaaagtcct atggacaagt
    13321 tattttggaa ggtctcggtc aggaattttt gatttctcaa caaaattttc acgattgtct
    13381 agtagaaacg ggctgttttc tgatataatg gaaaggatct attatatcag aaaaattttt
    13441 aatggcgtta agcacaatca actaacattt aaattagttt gaacttttat tatgctcttt
    13501 tagacaactg ttcaaatgtt ttcgaattgt ttttttgata aggacaataa atgaacaaat
    13561 ttttggtttt agtaaaccca attactgttc ttttcattag tgtcagttgc tatcaaaaca
    13621 gcttgtcata gttcgtgcga tcagtagcga gtattggtaa aactgaaacc gtagattatg
    13681 aaaaaatgat ctgttgatca ttaattaatc tgaagataag aagtcgataa aaaggagata
    13741 cgatgcccaa actatcaaag cgagttttag aaatgaaaga gagtgttact ctggctgcag
    13801 gtgctagagc taaggctttg aaagcgcagg gccgcgatgt actgaattta actttaggag
    13861 aaccagattt ttttacacct aagcacattc aagacaaggc gattgaatct attcaaaatg
    13921 gtacggctag cttttataca aatgcttctg ggcttccaga attaaaagct gcgattgcca
    13981 catacctgaa aaatcagtat gggtatcact tgtctcctga tcagattgtg gcaggaacag
    14041 gtgccaagtt catcctttat gcctttttta tggctgtttt aaatcctggt gaccaagttc
    14101 tcattccaac accatattgg gtatcttatt ctgaccaagt aaaaatggca gaaggtcagc
    14161 cgatcttcgt tcaaggacta gaagaaaatc aattcaaggt aactgttgac cagctggaaa
    14221 gagcaaggac aagtaagact aaagttgtcc ttatcaattc tccttccaat ccaacaggca
    14281 tgatttatgg tgctgaggaa ttaagggcca ttggagaatg ggcggtgcac aacgatattc
    14341 ttattctggc agatgatatt tacgggtcct tagtctataa cggcaatcag tttgttccta
    14401 tttcaacact ctcagaagcg attcggcgtc aaaccattac ggtcaatggc gtggctaaaa
    14461 gttatgccat gacaggctgg cgggttggtt ttgcagcagg tgaaccagag atcatttcgg
    14521 caatgagtaa gatcatcggg cagactacct ctaacctgac aaccgtttca caatatgctg
    14581 ctatcgaggc tttctgtggt agtcagtcat cacttgaaga gatgcgatta gcatttgaag
    14641 agcgccttaa tatcacttat ccattgttgt gtcaggtccc tgggtttgag gttgttaaac
    14701 cacaaggagc tttttacttc tttccaaacg ttaagaaagc catggaaatg acaggttttt
    14761 ccgatgtgac aagctttgct aatgctattt tagaggaagt cggattagct gttgtgagtg
    14821 gagcaggctt tggcgcaccg gaaaatgttc gtctgagtta tgctacagat atcgaaaccc
    14881 ttaaagaagc tgttcgtaga ctgcatgtct ttatggaaag taatgaaatt aattaaataa
    14941 aaatagagag aaacttatgt caaaaaaact tatttcaatt gttgatgtta aagattatgt
    15001 tggtcaagaa gttactattg gtgcttgggt tgctaacaaa tcaggtaaag gtaagattgc
    15061 gtttgtacag ttacgcgatg gttctgcttt tttccaaggt gtcgctttta aaccaaactt
    15121 cattgaaaaa tatggtgaag aatcaggtct tgaaaaattt gacgttatta aacgtctcaa
    15181 ccaagaaaca tctgtttatg taacagggat tgttaaagag gatgagcgtt ctaaatttgg
    15241 ctatgagctt gatattactg accttgaaat cattggagag tcacatgaat atcctataac
    15301 tcctaaagag catgggacag acttcttgat ggacaaccgt catctttggt tgcgttctcg
    15361 taaacaaatg gctgttatgc aaattcgtaa cgctattatt tatgcaactt atgaattctt
    15421 tgaccaaaat ggttttatca aatttgatag cccaatttta tcagaaaatg cagcagaaga
    15481 ttcaacagag ttattcgaaa cagactattt tgggaaacta gcatttctta gccaatctgg
    15541 tcaattatac cttgaagctg gagcaatggc tctaggccga gttttcgact ttggtccagt
    15601 ctttcgtgct gaaaaatcta aaacacgtcg ccatttaaca gaattttgga tgatggatgc
    15661 tgagtattct ttcttgtcac atgaggaatc acttgacctt caagaagctt atgttaaagc
    15721 attgatccaa ggcgttctag atcgtgcgcc tcaagcactt gatattttag aacgtgatgt
    15781 tgaggctctc aaacgttata tcacagagcc attcaagcgt gtttcttatg atgatgctat
    15841 tacacttctt caagagcatg aagcagatga agatacagat tatgaacatt tagagcatgg
    15901 tgatgacttt ggttccccac atgaaacttg gatttctaat tactttggag taccgacatt
    15961 tgtagtgaat tacccagcaa gctttaaagc attttatatg aaaccagttc ctggaaatcc
    16021 agaacgcgtt ctttgtgctg atcttttagc tccagaaggt tatggagaga tcattggcgg
    16081 ctcaatgcgt gaagacaact acgatgctct tgtggctaaa atggatgaac taggtatgga
    16141 taaatcagaa tatgactttt accttgacct tcgtaaatac ggctctgttc ctcatggcgg
    16201 ttttggtata ggtattgaac gtatggtaac ttttgttgct ggtaccaaac atattcgcga
    16261 agctattcca ttcccacgta tgttacatcg gattagaccc taataataca aaaagttcat
    16321 gtcatctatg aactttttgt attggtaaga agtgagtgtg ttataaaaac atcaatatgt
    16381 cctaaaggag agataagaaa tagtagagtt tgaacctaca tcctttgtga agataaattt
    16441 tggaagttta gtagatcagt tagcagataa gacaatatag ccttgctcaa gggatatttt
    16501 atagacaagt atttggacta cgattatcaa atagacactc tcatttgata ctaaaaaggt
    16561 ctcgtctatt aatataatag gagagctacg ggagttatta ttaaaattag ctgattttta
    16621 cagttcaaaa tgtgttacca ctttttcact tcttagcttt cttatgtatg tgatataatg
    16681 aaggtggacg gttcgataga gaaagggaaa ttgtaaatgt cagacaaaca cattaattta
    16741 gttattgtga caggaatgag cggcgctgga aaaacagttg ccattcagtc ttttgaggat
    16801 ctaggctact ttaccattga taatatgccc ccagccttgg ttccaaaatt tttagaatta
    16861 attgaacaaa ccaatgaaaa tcgtagggtg gctttggttg tcgatatgag aagtcgtttg
    16921 tttttcaagg aaattaattc taccttagat agtattgaaa gcaatcctag cattgatttt
    16981 cggattcttt ttttggatgc aacggatgga gaattggtgt cacgctataa agaaaccaga
    17041 cggagccacc ctttggctgc ggacggtcgt gtgcttgatg gtattcgatt ggaaagagaa
    17101 ctcctatctc ctttgaaaag catgagccaa catgtggtgg atacaacaaa attgacccct
    17161 agacaattgc gtaaaaccat ttcagaccag ttttctgaag ggtctaatca agcctctttc
    17221 cgtattgaag tgatgagctt tgggttcaaa tatggtcttc ctttggatgc ggatttggtt
    17281 tttgatgtgc gttttctacc caatccttat tatcaggtag agcttcgtga aaaaacagga
    17341 ctagatgagg acgtttttaa ttatgtgatg tctcacccag aatcagaggt gttttacaag
    17401 catttgttaa accttattgt ccctatctta ccggcttacc aaaaagaagg gaagtctgtc
    17461 ttgacggtgg ctatcggctg cacaggaggc caacaccgca gcgttgcctt tgcccattgc
    17521 ttggcagaaa gtctggcaac agattggtcg gttaatgaaa gccatcgtga tcaaaatcgt
    17581 cgtaaggaaa cggtgaatcg ttcatgaaaa atcctaaaat gactgttata ggtgggggta
    17641 ctggcatctc cattatccta aaaagccttc gtaatgaagc agttgatatt actgctgtgg
    17701 tcactgttgc agatgatggt ggttcctcag gagaacttcg taatgccatg caattagccc
    17761 cgccaggaga cttacggaat gtcttgttag cgatgagtga catgccaaaa ttttatgagc
    17821 gggttttcca ataccgtttt aacgagaatg atggagcctt ggctggtcac cctctaggca
    17881 atctcattat tgctggtatc tctgaaatgc aaggctcaac ctacaatgcc attcaaattt
    17941 taaccaaatt tttccatatt acaggtaaaa tttacccctc tagcgagcag gccttgaccc
    18001 ttcatgctgt ttttaaagat gggcatgaag tagcaggaga aagttctatt gccaaatacc
    18061 aaggcatgat tgaccatgtc tatgtgacca acacctacaa cgaccaaaag cctcaggcca
    18121 gtcgtaaggt ggttgaggct attctagaaa gtgacatgat tgtcttggga ccaggctcac
    18181 tgtttacctc tattttacct aatttggtca ttccagaaat taaagaagct ttgcgccaga
    18241 ctaaagcaga agtggtgtat atttgtaata tcatgaccca gtatggtgaa acagaacaat
    18301 tttcagatgc agaccatgtg gctgttttaa atcagcactt aggaagagat ttgattgata
    18361 cggttttggt aaatgtggct aaggtgccgc aggcttacat gaattctaac aaatttgatg
    18421 aatacctcgt tcaggttgat cacgactttg ctggcctttg cagggctgct aagcgtgtga
    18481 tttcgtctta ttttttacgg ttggagaatg gcggagcttt tcacgatggt aacttagtgg
    18541 tggaagaatt aatgaattta gtgaggatag tcaagcaatg agttttacaa ccaaggtcaa
    18601 agaggaatta attcacttgt ccacaggtga caacaatgaa ttggccgcca ttatcaaatt
    18661 atcaggcagc ttgggcttag ctcaccaaag ccttcattta tccattacca ctgaaaatgc
    18721 taaaattgcc cgctacattt attcttttat tgaagatgcc tatgttatcg tgccagaaat
    18781 caggtatcat caaaagacga acctgcgcaa aaaccgcgtt tacaccgtct atgttgagca
    18841 aggtgtggaa accattttag ccgatttgaa attagcggac tccttttttg gtctggaaac
    18901 aggcatcgaa cctcaggttt tatcagacga taatgctggc cgttcttatc ttaaaggggc
    18961 ttttctagcg gcaggtagca tcagagatcc tgagtcaggc aagtatcagt tagaaatcta
    19021 ttcagtttat cttgatcatg ctcaagattt agctcaactc atgcaaaaat ttatgctaga
    19081 tgccaaaacc attgagcata aaagcggtgc agttacttat ttgcaaaagg cagaagatat
    19141 catggacttt ttaattataa ttggtgccat gtcctgcaaa gaagactttg aagccatcaa
    19201 attacttcga gaagctcgaa atgatattaa ccgtgccaat aatgcagaaa cagctaatat
    19261 tgccaaaact atcagtgcta gcatgaaaac cattaataat attattaaaa tcatggacac
    19321 aattggttta gaaagtttac cgattgaatt gcaacaggta gcccaacttc gggttaagca
    19381 tccagactat tccattcaac aagttgctga tgcccttgag ttcccaatca ccaagagcgg
    19441 ggtcaaccat cgcttgcgta aaatcaataa aattgcagat gacttataga acatttttat
    19501 cgtatgagcc tttgttcata cgatttttct gtctaaaagt cgttttccat tgtttttttg
    19561 aagtgtctga tgttctgtga tatgataaaa gggataataa tgtttgtaaa ggagactgat
    19621 aatggcatgt acaactatac tagttgtagt gcctaaataa tgcttttaaa acttaaaaat
    19681 aatatcgatg ttatccatag taacctcgac tctatctatc aattgcttaa ctatcctaga
    19741 ttgaacatca tacgaagatt ttctaatgtc aaggttatcc atcagcattc caagagagtc
    19801 ttcgtttttc ttgtctaaat aattcaattt aattgctttg ttataatcat cttttaaatg
    19861 attgagttct tcgatgtctt tttttagttt tggtaggtca atcaaatcat taatatataa
    19921 atcgtttaga cgattgattt ttt
//
LOCUS       DAUNLR010000030        19821 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUNLR010000030 DAUNLR010000000
VERSION     DAUNLR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19821
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.030"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            209..1702
                     /gene="malQ"
                     /locus_tag="VLL59_001130"
     CDS             209..1702
                     /gene="malQ"
                     /locus_tag="VLL59_001130"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HER6509257.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEVVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            1737..4001
                     /gene="glgP"
                     /locus_tag="VLL59_001131"
     CDS             1737..4001
                     /gene="glgP"
                     /locus_tag="VLL59_001131"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HER6509258.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(4257..4877)
                     /locus_tag="VLL59_001132"
     CDS             complement(4257..4877)
                     /locus_tag="VLL59_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HER6509259.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(5179..5526)
                     /gene="ssrA"
                     /locus_tag="VLL59_001133"
     tmRNA           complement(5179..5526)
                     /gene="ssrA"
                     /locus_tag="VLL59_001133"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            5618..6232
                     /locus_tag="VLL59_001134"
     CDS             5618..6232
                     /locus_tag="VLL59_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HER6509260.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIALFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            complement(6359..7144)
                     /locus_tag="VLL59_001135"
     CDS             complement(6359..7144)
                     /locus_tag="VLL59_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509261.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(7154..7852)
                     /locus_tag="VLL59_001136"
     CDS             complement(7154..7852)
                     /locus_tag="VLL59_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509262.1"
                     /translation="MAHLLQIHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(7852..8223)
                     /locus_tag="VLL59_001137"
     CDS             complement(7852..8223)
                     /locus_tag="VLL59_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6509263.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            8408..11518
                     /locus_tag="VLL59_001138"
     CDS             8408..11518
                     /locus_tag="VLL59_001138"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HER6509264.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVAESDQELADCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAIEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEV
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            11598..12611
                     /gene="pfkA"
                     /locus_tag="VLL59_001139"
     CDS             11598..12611
                     /gene="pfkA"
                     /locus_tag="VLL59_001139"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HER6509265.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            12673..14175
                     /gene="pyk"
                     /locus_tag="VLL59_001140"
     CDS             12673..14175
                     /gene="pyk"
                     /locus_tag="VLL59_001140"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HER6509266.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            14393..14950
                     /gene="lepB"
                     /locus_tag="VLL59_001141"
     CDS             14393..14950
                     /gene="lepB"
                     /locus_tag="VLL59_001141"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HER6509267.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            15126..16940
                     /gene="glmS"
                     /locus_tag="VLL59_001142"
     CDS             15126..16940
                     /gene="glmS"
                     /locus_tag="VLL59_001142"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HER6509268.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            17136..17471
                     /locus_tag="VLL59_001143"
     CDS             17136..17471
                     /locus_tag="VLL59_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HER6509269.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            17578..18219
                     /locus_tag="VLL59_001144"
     CDS             17578..18219
                     /locus_tag="VLL59_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HER6509270.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            18229..18858
                     /locus_tag="VLL59_001145"
     CDS             18229..18858
                     /locus_tag="VLL59_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HER6509271.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            18874..19710
                     /locus_tag="VLL59_001146"
     CDS             18874..19710
                     /locus_tag="VLL59_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HER6509272.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQEKVAFTDPYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRMLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         6285 a         3296 c         3995 g         6245 t
ORIGIN      
        1 tattatcaat tccaatgaac agaatcttag tcagactatt tttgttcctt ttagtttaaa
       61 acaaagagaa agcgtccgtg atattagtca ttaagaacaa aaaaagtagc atttttaagg
      121 aatgttactt tttttaggaa actggttgac ttacgcaagc gcttgcgtta taatctcatc
      181 atgaatagat ttcacaagga gaaaaatcat gaacaaacgt gcaagcggta tcttaatgca
      241 tattagttcc ctgcctggga aatttgggat aggcactttt ggaaaatcag cttttgaatt
      301 tgttgatttt ctagcagaga cgaaacaaac ctattggcaa attctgcctt taacaacgac
      361 gagttttgga gattctcctt atcagtcatt ttcagctatt gctgggaaca cacatttcat
      421 tgattttgaa ttgctagtag atgatgaact tttagaagca gcagatttgt gtgatattac
      481 attcggcaca aatcctgaag tagtagacta tgctcagctt tttcaagtta gacgtccact
      541 tttagaaaaa gcagtgagag cttttgttgc cgaacaagaa aatgtgtgta aattagaagc
      601 ttttgaaaca gcttctagct ggttaactga ttttgctgaa tttatggctt taaaagaata
      661 ttttaacaat aaagccttac aagattggga cgacgaaact gtcattaaac gccaagaaga
      721 ctcacttaat aattaccgtg agttgcttgc aaaaaagatt acctatcata aagtctgtca
      781 atacttcttt taccaacaat ggtcagcctt gaaaacttac gctaaccata aagggataga
      841 aattattggt gatatgccta tttatgtttc tgcggacagt gtagaagttt ggacgatgcc
      901 tgagctattt aaagtagata gtgataaaaa gccattgttt attgcaggtg taccagcaga
      961 tggctttagt gaagatggtc agctgtgggg aaatccaacc tacaattggt ctgctcatga
     1021 aaagtctaat tttgcatggt ggatttatcg tattcaagaa agtttcaaac tatatgatca
     1081 gctaagaatc gatcatttta aaggcttctc agatttttgg gaaattcctg ctggtgataa
     1141 aactgctaga aatggccatt gggcctcagc cccaggtata gcgttatttt ctgcggttcg
     1201 tgaggcctta ggagagcttc ctatcatcgc agaaaacctt ggttatattg atgaaaaagc
     1261 agagcagcta ttagcatcaa caggctttcc tggcatgaag atattagaat ttggtttatt
     1321 tgatataacg agtcaaagta tagatttacc acattactat gaccgtaatt gtgtcgctta
     1381 cacagggact catgataacg aggtggttaa cggatggtat gacaatctta gtgaagaaca
     1441 agtacacttt gtaaataact atcttcacaa acatgcagat gaaagtatta caaaagccat
     1501 gctaagaaca atctttgctt ctgtttgtga tacagccatt ctttgcatcc aagatttatt
     1561 agataaagat ggtaagagtc gtatgaatat gccaaataca attggaggta attggcaatg
     1621 gcgtatgctt gacggtgaat tgaaccaaga tcacaaagat taccttattt atttaacaga
     1681 tctttatggt cgcgcaagat aatatttaaa tgttacatta ttgaaaagag gaagacatga
     1741 cacgctttac agaatatgtt gaaactaaac taggaaaatc acttacgcag gctagcaatg
     1801 aagagattta tctatcatta ttaaactttg tcaaagaaga agctagccac aaagctaaaa
     1861 atactgccaa acgcaaagtt tactatatct cagcagagtt tttgattggt aaattactat
     1921 caaacaacct gattaaccta ggaatttaca aagatatcaa agaagaattg gcagctgctg
     1981 gcaaatctat cgcagaagtc gaagatgttg aattagaacc atcactaggt aatggtggtt
     2041 taggacgcct tgcttcatgt tttattgact ctatttcatc tcttggtatt aatggtgaag
     2101 gggttggttt aaactatcat tgtgggttgt ttaagcaagt cttcaaacac aatgagcaag
     2161 aagctgagcc aaactactgg attgaagatg actcatggtt ggttccaaca gacatttctt
     2221 acgatgtgcc cttcaaaaac tttaccttaa aatctcgtct tgatcgtatt gatgttttgg
     2281 gttacaaacg tgacactaaa aactacctta acttgtttga tatcgagggc gttgattacg
     2341 ggttaatcaa agacggtatt tcatttgata aaacgcaaat tgctaaaaac ttgaccttgt
     2401 tcctctaccc agacgattct gacaaaaatg gggaattgct ccgtatttac caacagtact
     2461 ttatggtgtc aaatgcagcg caattaatca ttgatgaagc tatcgaacgt ggttcaaacc
     2521 ttcatgacct tgcagactac gcttacgtgc aaatcaatga cacgcatcca tcaatggtca
     2581 tcccagaatt aattcgtctc ttgactgaaa aacatggctt tgactttgat gaagcggtag
     2641 ctgttgtgaa aaatatggtt ggttacacta accacactat tcttgcagaa gcccttgaaa
     2701 aatggccaac tgcttactta aacgaagtag tgccacactt ggtaaccatc attgaaaaat
     2761 tggatgctct tgttcgttca gaagtgtctg atccagctgt tcaaattatt gacgaatcag
     2821 gtcgtgtgca catggcccat atggatattc attttgcaac aagtgtcaat ggggtagcag
     2881 cactccacac agaaatcttg aaaaacagcg aattaaaagc tttctatgac ctttacccag
     2941 aaaaattcaa caacaaaacc aacgggatta ctttccgtcg ttggctagaa tttgctaacc
     3001 aagacttggc tgattacatt aaagaactta ttggcgatga gtacttgact gacgcaacaa
     3061 aattagaaaa attgatggcc tttgcagatg ataaagctgt tcatgctaaa ttggctgaaa
     3121 tcaaattcaa caacaaatta gctcttaaac gttaccttaa agacaataaa gacattgagc
     3181 ttgatgaaca ttctattatt gatacccaaa tcaaacgttt ccacgagtac aaacgtcaac
     3241 agatgaatgc tctttacgtg attcacaaat atttggaaat taaaaaaggc aaccttccaa
     3301 aacgtaaaat cactgttatc tttggaggta aagcagcgcc tgcttacatc attgctcaag
     3361 acatcattca cttgatcctt tgcttgtctg aattgattaa caatgaccct gaagtaagcc
     3421 cataccttaa tgtgcatcta gttgaaaatt acaacgtgac agtagcagag cacttgattc
     3481 ctgcaaccga tatttctgaa caaatttcac tagcatctaa agaagcttct ggaactggta
     3541 atatgaaatt catgcttaac ggtgctttaa cgcttggtac aatggacggt gctaacgtag
     3601 aaatcgctga gcttgcaggc atggaaaata tctacacctt tggtaaagat tctgacacca
     3661 tcatcaacct ttatgcgact gcttcttatg tagcaaaaga ttactatgat aaccatcctg
     3721 ctattaaagc agcagtgaac tttattatca gtccagaatt gctagcattt ggcaacgaag
     3781 aacgtcttga tcgtctttat aaagaattga tttcaaaaga ctggttcatg actttgattg
     3841 accttgaaga gtacattgaa gtgaaagaaa aaatgttagc agactatgaa gaccaagatt
     3901 tatggatgac aaaagtggtc cataacatcg caaaagctgg attcttctca tctgaccgta
     3961 ccattgagca gtataacgaa gatatttggc attcacgata aaaaataata attgcaatgt
     4021 ggggtagcgg taccgtaaca tgcttaaact aaatcataag acagtagttt atgctgtctt
     4081 atgatttttc ttcagcttag attaattatt acattaagcg taaaacaagt ctgtttatcg
     4141 atctatgaag gcaattataa gaaattacac taaagttttt tattaaaatg gtataaaaag
     4201 attgatttcg gtgtacatcg aaatcaatct ttttagcaaa atatattacg cattttttat
     4261 tcttcaagtc ctacctgaga catttctgtt aactgattat tttcaaaaac gagagaaata
     4321 ttagctccgc ttgtatctgt ctttaagcca ctaacccaaa tcgcttgcaa agtttgatga
     4381 tcactagatg acgcttggct ataattatca ggttctgtta agatcttttt aacgtcttca
     4441 taagacattc ctttttgtaa ttgttggtat tccttttgcg ataagcctaa ctctcttgca
     4501 aaggtaaaat tagagatggt tttaacaata ctactatttt gataaagatt aacagtgaga
     4561 gtaacttgat caaactgcca agtataagcg tcgattgtta cttcgcctgc tgtttttgga
     4621 tcatgttggc taggctctcc aaagagtgaa ataagttctt caaggcttgt ccctcctgta
     4681 aatgaggaat caacagtcgc aagtttaatt ttttcaaagt tagcgcgttt atcttgatga
     4741 gcggcttggt gtagtcgggg agtaatgatt tctgaatcag acggttgagg ctctttatct
     4801 ttcgttgttg aacaagctac caaaaagcta gtaaaaaaag agatgagaag aagtgttagt
     4861 aagtgttttt ttgtcatatg ttatttccta aactattttt gctgtattat atcataaatt
     4921 ataaacaaga tatagctatg attccccata gcgcatgcgc tatggggaat ttagtactat
     4981 tttgattctt ttttttagat attcatgaaa aaaatggtca aaaagctctg atatgacaag
     5041 gttttgagtg gtattgatgg agtatcggta agcgtgatgg tatggctata gggataacgg
     5101 aaactcatga acaagacaaa aagaaaaaac cttgatgtaa caaggtttta gtaagttatg
     5161 attacttacg gtaagcattg atggagctgg tgggagtcga acccacgtcc aaacacctgc
     5221 caacatattt gtctacgtcc ataggttatg tcttcattta acaaactaaa gacacataac
     5281 tcaagccatt agtttgcgag tctatcaatc tcttgtcacg aaactagaca atttcgtaac
     5341 cgtagcttgc tattttgaga cttctaacag gacacaagca atcttgtaga agtcacgcta
     5401 gctggttttt aggcagctaa agcgtaagag tttgtatttt ttgcagttat atttaactgg
     5461 caatttacat ctgccgatgg gacgcaaaac atgcctcata atgcctgtcg aatccgtaac
     5521 aaccccaaat agataattaa ccaatttctt acactaacta ttctatcaaa acttttttta
     5581 aatagcaaaa ttttacagct tatggtatga ttagtctatg acaaaacgta attcaaaagc
     5641 ctatatatta tggcaaaaaa ttatcaaaat tttaggaatt attgcactaa ttggtacttt
     5701 tttcctcgct ttttggctgt atagactagg tatattaaac gatagtaatg ctcttaaaga
     5761 cttagtgcag cgctatagat tatgggggcc gtttgttttt attgtcgtgc agatcataca
     5821 gattgttttt cctgtgattc ctggaggcct tacgacagtt gcaggttttt taatctttgg
     5881 ccctgtaaca ggttttattt ataattatgt aggcatcatt attggcagta tagccctctt
     5941 cttgctcgtt aagacttatg gtcgtaaatt tatcttactc tttgtaaatg acaaaacatt
     6001 ttacaagtat gaaaggcgtt tggagacacc aggatatgaa aaattattta ttttttgtat
     6061 ggcatcgcct gtttctccag ctgatattat ggttatgatt acgggattga cggacatgtc
     6121 tttaaagcgc tttgtaacta ttcttttaat aactaaacca atttctatta tcggctacag
     6181 ttatttattt atttttggaa aagatgttat atcttggttc ttacagcatt aaggtttggt
     6241 gttaatttga taaaccgctt ctatttgatg gaagacggtt tttttattta ctatgaacac
     6301 tgaaaaaaac tttcttttaa actatagtgt gtcatagttt aaaagaaagt cttaacgctt
     6361 actgtaggtt gagtttattt ttgataataa aattagtggc gaggtaaaac attatcattt
     6421 caataaattg ttccaaaata agaagataaa ttgttttttg ctcagtaaat gggaaactat
     6481 cggcacttgt attaatatta aagatgtgac tgtgaacata tgttgcagca acgctaatca
     6541 gaataactaa tataaaatat gcaataaagg ccatcaagcc tcgccgattg gaaaaaagtt
     6601 gacctataga aatggaaaga taaattaata agatactcgt aaatgttgat aataggacat
     6661 aggctagtac agttagcata ttgatgaaat aatccatctt aaaactatta aagaatcctt
     6721 ctaatagttc gttgatgtta aacattggta caattacaat agcgatagca aatgcaagga
     6781 tgatagtatt gaaaacactg caaataaaag aagctagtag ttttgataaa ataatttgat
     6841 gcgaattaac gggtaaagtc aacgttaagt atccttcccg tccaaaaaca cttttgctaa
     6901 aacgtttgat aatgataagt aatgttgata agagggaacc agcgatcagg gagccaaaag
     6961 ttaaacctaa tgtcagaggt aacatcttat tggttagtac tccaaatagt ccatcactat
     7021 tactttgagc aaacagtttt atcgtaaatg acaaaatggc agcgatggca ataacgaaag
     7081 cattaagcgc aaagtaccat tttccaatag atctaaattc gtattttaat aattttccaa
     7141 acatgatatc ctcctaaacc ttataagttt ccctaaagag ggaatcaatg gattgctggt
     7201 attcttgtct tagatcatca gcattgccag ataagaaaag tcttccttgt ttcaagaaaa
     7261 tgacttcgtc aaggataggt tcaatgtccg aaatcaagtg ggttgagata ataacagaag
     7321 cattttcaca ataactatta atgatggttt ttaggatgta gtctcttgca gcagggtcaa
     7381 ctccaccaat aggttcatca agtacataga gtctggcttt acgactcatc acaagaatta
     7441 attgtacttt ttctttgttt cctttggata gagttttgaa gcggtcttca gggtctagtt
     7501 ctaaatctct tagaaggctt gttgctttgg atttgtcaaa gtcgctgtaa aaatcactaa
     7561 agaactccaa catgtcctta attctcatat tttcattgag ataagtagta tctggtaaat
     7621 aagaaataat tttttttgtc tcaacacagg gacggtagcc atcaatgaca atttctcctt
     7681 tatttggttg taaaaggcca ttaatgagtt taattaaagt tgttttacca cttccatttg
     7741 gacctaataa tccgataatt ttaccgttcg ggatagtaat ggttaagtca tcaatagctt
     7801 ttttttcacg gtaagatttt gaaacatgat gtatttgcaa taggtgtgcc attattgtga
     7861 atcctccttt aaaaagctcg tcaaaacagg gataatctca gtgtgactaa atcccatttt
     7921 tgtcatattg gtgataaatg attctaattc actaattgct aactctcgtc ttttacgagc
     7981 aattaatttt tgatcgtcag tcacaaaacg gccagcagta cgttgcgaat aaaccattcc
     8041 ttcccgttca agttctgtaa acgctcgttg catggtgtta ggattaacac ctgcgatttc
     8101 tgcatattca cgaacagttg gaagttgatc accactcttg atttcttggc taataatttg
     8161 catcatgaca tgttgtgcta tctgcgcata aataggagat ttttcatcaa atttccaaga
     8221 catgtggtct cctttctgag taatatagat atttgtacta attaaatggt acagaaaaaa
     8281 aaagggaatg tcaagtttta tgccattttt cactctttga gaagtagacg tagattagag
     8341 agaaaattga agcaagaaaa cctttttcat agtataatag ggaacaagat aaccaaagga
     8401 ggaacttatg tttgctcaac ttgatactaa aactgtatac tcatttatgg atagtttaat
     8461 tgacttaaat cattattttg aacgagcaaa gcaatttggt taccacacca taggaatcat
     8521 ggataaggat aatctttatg gtgcttacca ttttattaaa ggttgtcaaa aaaatggact
     8581 gcagccagtt ttaggtttgg aagtagagat tctctatcaa gagcggcagg tgctccttaa
     8641 cttaatcgcc cagaatacac aaggctatca tcagctttta aaaatttcca cggcaaaaat
     8701 gtctggcaag cttcatatgg attacctctg ccaacatttg gaagggatag cggttattat
     8761 tcctagtaag ggttggagcg atacattagt ggtccctttt gactactata tcggtgttga
     8821 tcagtatact gatttatctc atatggattc taagaggcag cttatacccc taaggacagt
     8881 tcgttatttt gcgcaagatg atatggaaac cttgcacatg ttgcatgcca ttcgagataa
     8941 cctcagtctg gcagagaccc ctgtggcaga aagtgatcaa gagttagcag attgtcaaca
     9001 actaaccacc ttctatcaaa cacactgccc tcaagctcta cagaatttag aagacttagt
     9061 gtcaggaatc tattatgatt tcgatacaaa tttaaaattg cctcatttta atagagataa
     9121 gtctgccaag caagaattgc aagacttgac tgaggctggt ttgaaggaaa aaggattgtg
     9181 gaaagagcct tatcaatcgc gcttactgca tgaattggtc attatttctg acatgggctt
     9241 tgatgattat tttttgattg tgtgggattt acttcgcttt ggacgcagta aaggctatta
     9301 tatgggtatg ggacgtggct cggcggcagg tagtctagtg gcttatgctc tgaacattac
     9361 agggattgat ccagttcaac atgatttgct atttgagcgc tttttaaaca aagaacgtta
     9421 tagcatgcct gatattgata tcgatcttcc agatatttac cgttcagaat ttctacggta
     9481 tgtccgaaat cgttatggta gcgaccattc ggcgcaaatt gtgacctttt caacctttgg
     9541 ccctaaacag gctattcgtg atgttttcaa acggttcggg gttccagaat acgaactgac
     9601 taatctcact aaaaaaattg gttttaaaga tagcttggct actgtctatg aaaagtcaat
     9661 ctcttttagg caggttatta atagtagaac tgaatttcaa aaggcctttg ctattgccaa
     9721 gcgtatcgaa ggaaatccaa gacaaacgtc cattcacgca gctggtattg tgatgagtga
     9781 tgataccttg accaatcata ttcctctaaa atcgggcgat gacatgatga tcacccagta
     9841 tgatgctcat gcgatcgaag ctaatggcct gttaaaaatg gattttttgg ggttaagaaa
     9901 tttgaccttt gttcaaaaaa tgcaagagaa ggttgctaaa gactacgggt gtcagattga
     9961 tattgcagcc attgatttag aagacccgca aacgttggca ctttttgcta aaggggatac
    10021 caagggaatt ttccaatttg aacaaaatgg tgctattaat cttttaaaac ggattaagcc
    10081 acaacgtttt gaagaaattg ttgccactac cagtctaaat agaccagggg caagtgacta
    10141 taccactaat ttcattaaac gaagagaagg acaagaaaaa attgatttga ttgatcctgt
    10201 gattgctccc attttagagc caacttacgg tattatgctt tatcaagaac aagttatgca
    10261 gattgcacag gtttatgctg gttttacgtt aggcaaggcc gacttgttaa ggcgtgccat
    10321 gtctaaaaaa aatctacaag aaatgcaaaa aatggaagaa gactttattg cttctgctaa
    10381 gcacctaggg agagctgaag aaacagctag aggacttttt aaacggatgg aaaaatttgc
    10441 aggttatggt tttaaccgca gccatgcctt tgcctattca gctttagctt ttcaattggc
    10501 ttatttcaaa gcccattacc cggctgtttt ttacgatatc atgatgaatt attctagcag
    10561 tgactatatc acagatgctc tagaatcaga ttttcaagta gcgcaagtta ccattaatag
    10621 tattccttac actgataaaa ttgaagctag caagatttac atggggctga aaaatattaa
    10681 ggggttgcca agggattttg cttattggat tattgagcaa agaccattta atagcgtaga
    10741 ggattttctc actagaactc cagaaaaata tcaaaaaaag gttttccttg agcctctgat
    10801 aaaaataggt ctgtttgatt gctttgagcc taaccgtaaa aaaattctgg acaatttgga
    10861 tggtttactg gtatttgtta atgagcttgg ttctcttttt tcagattctt cctttagttg
    10921 ggtagatacg aaagattact cagcaactga aaaatattct ttggaacagg aggtcgttgg
    10981 agttggcatg agcaagcatc ctttaattga tattgctgag aaaagtaccc aaacttttac
    11041 tcccatttca cagttagtca aagaaagcga agcagtcgta ctgattcaaa tagatagcat
    11101 taggatcatt agaaccaaaa caagtgggca gcaaatggct tttttaagtg tgaatgacac
    11161 taagaaaaag ctcgatgtca cactttttcc acaagagtat gctatttata aagaccaatt
    11221 aaaagaagga gaattctatt acttaaaagg tagaataaaa gaaagagacc atcgactgca
    11281 gatggtgtgt cagcaagtgc aaatggctat tagtcaaaaa tattggttat tagttgaaaa
    11341 ccatcagttt gattcccaaa tttctgagat tttaggtgcc tttccaggaa cgactccagt
    11401 tgttattcac tatcaaaaaa ataaggaaac aattgcatta actaagattc aggttcatgt
    11461 aacagagaat ttaaaggaaa aacttcgtcc ttttgttctg aaaacggttt ttcgataaaa
    11521 atggacaatt agtgaagtat tttgcaaatg aatgtgctat aataagaccg ttaaattaat
    11581 taaaggagta ccagaaaatg aaacgtattg ctgttttaac cagtggcggt gacgctcctg
    11641 gtatgaatgc tgctattcgt gcagtcgttc gtaaagcaat ctcagaagga atggaagttt
    11701 atggtatcaa ccgtggctat gcaggtatgg ttgatggcga cattttccca ctgggttcaa
    11761 aagaagttgg tgataaaatc tcacgtggtg gaactttctt atactcagct cgttatccag
    11821 agtttgctca acttgaaggt caattggctg gtattgagca acttaaaaaa catggtattg
    11881 agggtgttgt tgttattggt ggggatggtt cttatcatgg cgctatgcgc ttgacagagc
    11941 acggcttccc agcggtaggt atcccaggaa caatcgataa cgatattgcg ggaactgact
    12001 acactatcgg atttgataca gcagttaaca cagcagttga agctattgat aaacttcgtg
    12061 acacctcatc aagtcacgga cgtacttttg tggttgaagt gatgggtcgc aatgcgggtg
    12121 atattgctct ttgggcaggt attgctagtg gtgctgatca aatcattgtt ccagaagaag
    12181 agtttgatat tgaaaaagtg gcatcaacaa tccaatatga ttttgaacac aaaggtaaaa
    12241 atcaccacat tatcgtctta gctgaaggtg ttatgagcgg tgaagctttt gctcaaaaac
    12301 tgaaagaagc tggtgataag agtgaccttc gtgtgacaaa tcttggccac attcttcgtg
    12361 ggggttcacc aactgctcgt gaccgtgtca ttgcttcttg gatgggttca catgctgttg
    12421 agctacttaa agaaggcaaa ggtggtttgg ctgttggtat tcacaatgaa gaacttgttg
    12481 aaagcccaat ccttggtact gcagaagaag gtgctttgtt cagcttgact gaagaaggca
    12541 agattattgt taataatcca cacaaagctc gtttagactt tgcagctttg aaccgttcat
    12601 tgtcacaata agtttagtta aaattgttaa atcgtcaatt attgacaaaa aataagggag
    12661 tttcagagta aaatgaataa acgcgtaaaa atcgttgcaa cacttggtcc tgcggttgaa
    12721 atccgtggtg gtaaaaaata cggagaagat ggctactggg ctggtcaact tgatgttgaa
    12781 gaatctgcaa aaaaaatcgc tgaattaatt gaagctggtg cgaatgtttt ccgtttcaat
    12841 ttctcacatg gtgaccacaa agaacaaggt gaccgtatgg caactgttcg ccttgcagaa
    12901 gaaattgctc gtcaaaaagt tggtttcctt ttggatacta aaggtcctga aatgcgtacg
    12961 gaattgtttg cagatgatgc taaagagttt agctatgtta ctggagaaaa aatccgtgta
    13021 gcgactacac aaggtattca atcaactcgc gatgttattg ctttgaacgt tgctggtagc
    13081 cttgacatct acgatgaagt agaagtaggt catactattc ttatcgatga tggtaaactt
    13141 ggtttgaaag tgatcgacaa agatatcgca acacgtcaat ttatcgttga agtagaaaac
    13201 gacggtatta ttgctaaaca aaaaggtgtt aatatcccta acactaaaat tcctttccca
    13261 gcacttgcgg aacgcgacaa tgctgacatc cgttttggtc ttgaacaagg acttaacttt
    13321 attgcaatct catttgttcg tacagccaaa gacgttgagg aagttcgtga aatctgtcgc
    13381 gaaactggta acgaccatgt gcaattattt gctaagattg aaaaccaaca aggtatcgat
    13441 aatcttgatg aaatcatcga agctgctgat ggtatcatga ttgcacgtgg cgacatgggt
    13501 atcgaagtac catttgaaat ggttccagtt ttccaaaaaa tgattatcac taaagtgaat
    13561 gcagctggta aagcagttat cacagcaaca aacatgcttg aaacaatgac tgaaaaacca
    13621 cgtgcgacac gttctgaagt atctgacgtc ttcaatgctg ttatcgatgg tactgatgca
    13681 acaatgcttt caggagagtc agctaacggt aaatacccgg ttgaatctgt tcgtacaatg
    13741 gcgactattg atcgtaatgc acaaactctt cttaacgaat atggtcgttt agattcatct
    13801 gcctttccac gtaccaataa aacagatgtt attgcttcag ctgttaaaga tgccactcat
    13861 tcaatggaca tcaaacttgt tgtgactatt actgagacag gtaatacagc tcgtgcgatt
    13921 tctaaattcc gtccagatgc ggacatctta gctgtaacat ttgatgaaaa agtacaacgt
    13981 gctttgatga ttaactgggg tgttattcct gttcttgctg aaaaacctgc atctactgat
    14041 gacatgtttg aagtagcaga gcgtgttgct gtggaggcag gcttagttca atctggggat
    14101 aatattgtta ttgttgctgg tgttccagtt ggtactggtg gaacgaatac tatgcgtgtt
    14161 cgtacagtaa aataaatgtg ttataactat ttacctaaag gttagaaggc aagcttctaa
    14221 ccttttttga tatcaaaaat atcatgttaa ttcactagtg ttaatttact ttaatgagtc
    14281 taagtttgta ttttatacag aatgagaaac gtttattggt attgatcaaa aattgtttac
    14341 tttttttcta gcttagaaca tggtataata agacaataga ctaggagtta atatggtaaa
    14401 gcgagatttt ataagaaata tattattgtt attaattgtg attattgggg ctattttgtt
    14461 gagaatcttt gttttttcaa cttttaaagt ttctccagaa acagctaata cttatttaaa
    14521 gagtggtgat ttagtcacaa tcaaaaaaaa tattcagccc aaatataaag attttgtggt
    14581 ttatagagtt ggaaaaaaag attatgtcag tcgagtcatt gctgttgaag gcgatagcgt
    14641 gacttatatg gacgatattt tttacctcaa taatatggta gagtcacagg cttaccttga
    14701 aaagatgaaa gcacattact tgaatcatgc accgtttggc acattgtata cagatgattt
    14761 tacagttgct accattacag ctgataagta tcaaaaagtt cctaagggga agtatcttct
    14821 tttgaatgat aaccggaaaa atacgaatga cagtcgtcga tttgggttaa taaatgcctc
    14881 gcagattaaa ggtttagtga cctttagagt tttgcctctc agcgattttg gatttgtaga
    14941 agtagagtag ttgtcaggct actctacttt ttttataatt agactatacc aattttatgt
    15001 ttgacaagac attgtggata ttatatactg taaacataat gtttttatcg gtataatatg
    15061 actataccaa ttattgaaat tatgagagaa agtagcaagt taacgaactt gttaaggtaa
    15121 ttaagatgtg tggaattgtt ggagttgttg gaaatcgcaa tgcaacggat attttaatgc
    15181 aaggccttga aaagcttgaa taccggggtt atgattcagc aggaattttt gtggctaatg
    15241 ccaatcaaac aaacttgatt aaatcagtgg ggcggattgc tgatttgcgt gccaagattg
    15301 gcattgatgt tgctggttca acagggattg gtcacacccg ttgggcaacg catggccaat
    15361 caacagagga taatgcccat cctcacacgt cacaaactgg acgttttgta cttgttcata
    15421 atggtgtgat tgaaaattac cttcacatta aaacagagtt cctagctgga catgatttta
    15481 aggggcagac agatactgag attgcagtac acttgattgg aaaatttgtg gaagaagaca
    15541 agttgtcagt actggaagct tttaaaaaag ctttaagcat tattgaaggt tcctacgcct
    15601 ttgcgttaat ggatagccaa gcaactgata ctatttatgt ggctaaaaac aagtctccat
    15661 tgttgattgg acttggtgaa ggttacaaca tggtttgttc agatgccatg gccatgattc
    15721 gtgaaaccag tgaatttatg gaaattcatg ataaggagct agttatttta accaaagata
    15781 aggtaactgt tacagactac gatggtaaag agctgatacg agattcctac actgctgaat
    15841 tagacttatc tgatattggc aaagggactt atcctttcta tatgctgaaa gaaattgatg
    15901 agcaaccaac cgtaatgcgt caattaattt caacttatgc agatgaaact ggtaacgtac
    15961 aggttgatcc agctatcatt acctctatcc aagaggctga ccgtctttat attttagcgg
    16021 cagggacttc ctaccatgct ggttttgcaa caaaaaatat gcttgagcaa ttgacagata
    16081 caccagttga gttgggagtg gcttctgagt ggggttacca catgcctctg cttagcaaga
    16141 aaccaatgtt tattctacta agccaatcag gagaaaccgc agatagtcgt caagttttag
    16201 taaaggcaaa tgctatgggt attccgagtt tgacagtaac taacgttcca ggatcaacct
    16261 tatcacgtga agcaacatac accatgttga ttcatgctgg acctgaaatt gctgttgcgt
    16321 ctacaaaagc ttacactgca caaattgctg cccttgcctt tttggctaag gcagttggtg
    16381 aggcaaatgg taagcaagaa gctcttgact ttaacttggt acatgagttg tcattggttg
    16441 cccaatctat tgaggcgact ttgtctgaaa aagatctcgt ggcagaaaag gttcaagctt
    16501 tgctagctac tactcgtaat gctttttaca ttgggcgtgg caatgattat tacgttgcga
    16561 tggaagctgc tttgaaatta aaagagattt cttatattca atgcgaaggc tttgcggctg
    16621 gtgaattgaa acatggaacc atttcattga ttgaggagga cacgccagta atcgctttaa
    16681 tatcgtctag tcagttggtt gcctctcata cgcgtggtaa tattcaagaa gttgctgccc
    16741 gtggggctca tgttttaaca gttgtggaag aagggcttga ccgtgaggga gatgacatta
    16801 ttgtcaataa ggttcatcct ttcctagccc cgattgctat ggtcattcca actcaactga
    16861 ttgcttacta cgcttcatta caacgtggac ttgatgttga taagccacgt aatttggcta
    16921 aagctgtaac agtagaataa atgattataa tggataaggc aaccatctgt taggtggttg
    16981 ctttttgttt ttaggagaat agcagagctt agaaaatggc cttgagaaaa gctatacaag
    17041 aagaatagtc atcttctgat gagaacgtat tcatcttgtc aaatcattga ttctaaagta
    17101 aaatggtaac attaagaaat gtttaggagt gtaagatgtc attaccaaat tgtttgcaat
    17161 gccagtctga atatgtttac gaagatggtc ttttattaat ctgtccaatg tgtgcttttg
    17221 aatggacacc aggcgaagaa gcgactgaag aagaaggact tgttgtttta gatagcaatg
    17281 gtgtccgact gtctgatggt gataccatta ctgtggttaa agatttgaaa gtaaaaggcg
    17341 ctccaaaaga cctgaaacaa gggactcgtg ttaaaaatat tcgcctggtg gaaggtgatc
    17401 ataacattga ttgtaagatt gatgggtttg gcgcgatgaa attgaaatca gaatttgtca
    17461 agaaaatcta ataataatac gcaaccagct gatctggttg tatttttata aaaaaacctc
    17521 tccccaaata cgttcaaatt tggtataata gtaaaatatt cagttttagg aggcaacatg
    17581 acctatattc agcaagtttt acccagctta ttagatggtg ccttggtgac cttacaagta
    17641 ttctttattg ttatcattct ttctataccc ttaggggcta ttttagcttt cttgatgaag
    17701 attcccttta aaccgctaca gtggtttttg accctatacg tgtggatgat gcgagggaca
    17761 ccattactac ttcaattgat ttttttctat tatgttttgc caagtgtggg gattagtttt
    17821 gatcgaatgc cagctgctat tttggcgttt actttgaatt atgctgccta ctttgctgaa
    17881 atttttagag gtgggattga ggctattcca aaaggtcaat atgaagcagc taaagtatta
    17941 aagttaaaac ctcttcaaac cattcgttat attattttgc ctcaagtgtt taaaattgtg
    18001 ttaccaagtg ttttcaatga agtcattaat ttggtcaaag attcttccct tgtctatgta
    18061 ctcggtgtag gagatctttt attagcaagt aagacggcag ccaataggga tgcaacctta
    18121 gcccctatgt ttatcgctgg tcttatctat ttgcttttaa ttggactggt cacgattatt
    18181 tcaaaacaag ttgaaaaacg gtttaattat tatcagtaag gaggcttcat gttagaactc
    18241 aaaaatattt ccaaacagtt tggtcaaaaa accatttttg atggctttaa tctaaccgtt
    18301 caagacggag aagtgctctc tttggtaggc ccatcaggtg gcggtaagac aacactctta
    18361 cggatgttgg ctggtcttga atctattgat tcaggtcaag tcttttacaa tggcgaagat
    18421 gttggtattg atcatttgga aaatcgtaac ttgcttggat ttgtttttca agattttcaa
    18481 ttgtttcctc atcttaccgt tttagacaac ctaacgctgt ctccaacaat tacaatgggc
    18541 aagcaaaaat ctgacgctaa agaaaaggct ttggatttac tggcacgttt aggattaaaa
    18601 gaacatgccc aagtttatcc ctattcgtta tctggaggtc aaaaacaacg ggttgctttg
    18661 gcaagagcca tgatgattga ccctcaaatt atcggttacg atgaaccgac cagtgctcta
    18721 gatcctgaat tacgtcagac ggtagaagcc ttgattgttc aaaaccgtga aatgggaata
    18781 actcaaattg tagtcactca cgatcttgtt tttgccgaag ccatctcaga tcgtattatt
    18841 agggttaatc ctaaatagaa gaggacccaa aagatgatta taaaaaaaag aaccgtagca
    18901 attttagcca tagctagtag ctttttcttg gtagcttgtc aagctactaa aggtcttaaa
    18961 tcaggagatg cttggggagt ttaccaaaag caaaaaagta ttacagttgg ttttgacaat
    19021 acgtttgttc ctatgggcta taaggatgaa agcggcaaat gcaaaggttt tgatattgat
    19081 ttggctaaag aagtttttca ccaatatgga ctcaaggtta actttcaagc tattaattgg
    19141 gacatgaaag aagcagaact aaacaatggt aaaattgatg taatctggaa tggttattca
    19201 ataactaagg agcgtcagga aaaggttgcc tttactgatc cttacatgag aaatgaacaa
    19261 attattgttg tcaaaaaaag atctgatatt aaaacaatat cagatatgaa acataaagtg
    19321 ttaggagcac aatcagcttc atcaggttat gactccttgt taagaactcc taaactgctg
    19381 aaagatttta ttaaaaataa agacgctaat caatatgaaa cctttacaca agcttttatt
    19441 gatttaaaat cagatcgtat cgatggaata ttgattgaca aagtatatgc caattactat
    19501 ttagcaaaag aagggcaatt ggagaattat cggatgatcc caacgacctt tgaaaatgaa
    19561 gcattttcgg ttggacttag aaaagaagac aaaacgttgc aagcaaaaat taatcgtgct
    19621 ttcaggatgc tttatcaaaa tggcaaattt caagctattt ctgagaaatg gtttggagat
    19681 gatgttgcca ctgccaatat taaatcttaa aaaggacact tgtccttttt ttgtttaaca
    19741 ggtgagatct agcagacaaa gtcagctaga tgatttaata aaaatcttag tttaaggttt
    19801 tttattaaac tgtatttttt c
//
LOCUS       DAUNLR010000031        19128 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUNLR010000031 DAUNLR010000000
VERSION     DAUNLR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19128
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.031"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            65..1261
                     /locus_tag="VLL59_001147"
     CDS             65..1261
                     /locus_tag="VLL59_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HER6509273.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLEAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQAAPAAQSSNAIEPA
                     ALTAPASHSARPQVSYSSVNNYPVGQCTWGAKSLAPWAGNNWGNGGQWAASAQAAGYS
                     VGSTPMVGAIAVWNDGGYGHVAVVVEVQSSSNIRVMESNYSGKQYIADHRGWFNPTGV
                     TFIYPH"
     gene            1514..2476
                     /locus_tag="VLL59_001148"
     CDS             1514..2476
                     /locus_tag="VLL59_001148"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HER6509274.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            2662..3417
                     /gene="recO"
                     /locus_tag="VLL59_001149"
     CDS             2662..3417
                     /gene="recO"
                     /locus_tag="VLL59_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HER6509275.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            3520..4527
                     /gene="plsX"
                     /locus_tag="VLL59_001150"
     CDS             3520..4527
                     /gene="plsX"
                     /locus_tag="VLL59_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HER6509276.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIMTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            4520..4762
                     /locus_tag="VLL59_001151"
     CDS             4520..4762
                     /locus_tag="VLL59_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HER6509277.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMRDVLDYLVQRLT"
     gene            4913..5617
                     /locus_tag="VLL59_001152"
     CDS             4913..5617
                     /locus_tag="VLL59_001152"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HER6509278.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVTAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            5741..9466
                     /locus_tag="VLL59_001153"
     CDS             5741..9466
                     /locus_tag="VLL59_001153"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HER6509279.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFENYQADDFTAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAEIRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPNDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKDNFSQFEAIQAQHKIT
                     AASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVCDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            9627..11081
                     /locus_tag="VLL59_001154"
     CDS             9627..11081
                     /locus_tag="VLL59_001154"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HER6509280.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNPNFIGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDSGIQCNRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     HLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAADEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            11109..12131
                     /locus_tag="VLL59_001155"
     CDS             11109..12131
                     /locus_tag="VLL59_001155"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HER6509281.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVRAALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            12299..12853
                     /gene="purN"
                     /locus_tag="VLL59_001156"
     CDS             12299..12853
                     /gene="purN"
                     /locus_tag="VLL59_001156"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HER6509282.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLTGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            13037..14584
                     /gene="purH"
                     /locus_tag="VLL59_001157"
     CDS             13037..14584
                     /gene="purH"
                     /locus_tag="VLL59_001157"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HER6509283.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(14642..15766)
                     /locus_tag="VLL59_001158"
     CDS             complement(14642..15766)
                     /locus_tag="VLL59_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HER6509284.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKIG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRRTWVNADKANKL"
     gene            16019..17284
                     /gene="purD"
                     /locus_tag="VLL59_001159"
     CDS             16019..17284
                     /gene="purD"
                     /locus_tag="VLL59_001159"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HER6509285.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGVPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVRPVLEGMVAEGRPYLGVLYVGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGAKFVENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            17562..18053
                     /gene="purE"
                     /locus_tag="VLL59_001160"
     CDS             17562..18053
                     /gene="purE"
                     /locus_tag="VLL59_001160"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HER6509286.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            18040..19113
                     /gene="purK"
                     /locus_tag="VLL59_001161"
     CDS             18040..19113
                     /gene="purK"
                     /locus_tag="VLL59_001161"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HER6509287.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPTNDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IFEKDFLANKAGVTVAPYKVVMSSLDLEGLDFTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVAQNPSAHLHMYGKLE
                     AKHNRKMGHVTLFAEDADEVEEF"
BASE COUNT         5636 a         3588 c         4346 g         5558 t
ORIGIN      
        1 attaaatact tttttttttg gtaaaatata agatgtctta tcgaaaagga gtagtttttt
       61 tattatgaaa aaaagaattt tatcagcagt tcttgtaagt ggtgttaccc tcggagcagc
      121 tacaactgta ggagcggagg atttaagtac taagattgct aagcaagatt ctattatctc
      181 aaatctgact acagagcaaa aagctgcaca gaatcaagtt tcagcgttac aggctcaagt
      241 aagttcacta caatctgaac aagataaact gaccgcaaga aatacagaac ttgaggcgct
      301 ttcaaagcga tttgagcaag aaattaaggc tctaacaagt caaattgttg ctcgtaatga
      361 aaaattaaaa aatcaagctc gtagtgctta taaaaacaat gaaacttctg gttatattaa
      421 tgcacttttg aattctaaat caatttctga tgttgtaaac cgtttagtag caattaatag
      481 agctgtctct gctaacgcta aattgttaga acaacaaaaa gctgataaag tttcccttga
      541 agaaaagcaa gctgctaacc aaacagctat taataccatt gccgctaata tggcaatggc
      601 tgaagaaaac caaaatacat tacgtactca acaagctaat ttggaagctg caactgcaaa
      661 tttagctctc caattagcat ctgctactga agataaagct aatttggtag ctcaaaaaga
      721 agctgcagaa aaagctgctg ctgaagcctt agcacaagaa caggctgcta aagttaaggc
      781 acaagaacag gctgcacaac aagcagcatc tgttgaagca gcaaaatctg ctattactcc
      841 agcaccacaa gctgctccgg cagcgcaaag tagtaatgct attgaaccag ctgcactcac
      901 ggctccggca tctcattctg caagaccaca agtttcatat agttctgtta ataattaccc
      961 agtaggacaa tgtacatggg gtgcgaaatc attagctcca tgggcaggaa acaattgggg
     1021 taacggtgga caatgggctg caagcgctca agcagcgggc tactctgtag gatctacacc
     1081 tatggtagga gctattgcgg tttggaatga tggcggttat ggtcacgtcg cagtagttgt
     1141 tgaagttcaa agttcatcaa atattcgagt gatggaatca aactacagtg gtaaacagta
     1201 tattgctgac caccgtggct ggtttaatcc aacaggtgtt acatttattt atccacacta
     1261 acatattatt taggttagaa cagttgttct aacctttttg attactccta ttgtggaata
     1321 gttctgagag tattgacgat atagttaatt tataagagag ttgtttggcc aatcgcttat
     1381 gtataatata agagaagtat ataaagtcga taaaaggtat atttaataca ttctttaacg
     1441 gtttttcaat ttcatttgat aattcacttg aaaagcgtta aaatggtata ggattaaaac
     1501 tttggaggaa aaaatgtctt attctgattt aaaattgttt gctttatcgt caaacaagga
     1561 attagcagaa aaagttgcgt ctgcaatggg tattcaactt ggaaagtcta cggttcgcca
     1621 gttttcagat ggtgaaatcc aagtaaatat tgaagaatca attcgtggtc atcatgtctt
     1681 tattttgcaa tcaactagct cacctgtcaa tgacaattta atggaaattt tgattatggt
     1741 cgatgcttta aagcgtgcta gtgctgaaaa aatttcagtt gtgatgcctt actacggcta
     1801 tgcacgccaa gaccgtaaag cgcgttctcg tgaacctatt acttcaaaat tagttgctaa
     1861 tatgttagaa gttgctggtg tagatcgctt attaacggtt gatttacatg ctgctcaaat
     1921 tcaagggttc tttgatattc cagttgatca cttgatgggt gcacctttaa ttgcagacta
     1981 ttttgatcgt catggtttag tgggtgaaga tgttgtcgtt gttagtcctg accatggtgg
     2041 tgtgactcgt gcgcgtaaat tagcacaatt cctccaaaca ccaattgcaa ttatcgataa
     2101 gcgtcgtagt gtggataaga tgaacaccag tgaagtgatg aatattatcg gaaatgtttc
     2161 gggcaagaaa tgtatcttga ttgacgatat gattgatacc gcagggacta tttgccatgc
     2221 agcagatgcg cttgctgaag cgggggcaac agctgtgtat gcgtcatgta cgcatcccgt
     2281 tctttctgga ccagcacttg ataatattca acgttcggct atcgaaaaac taattgttct
     2341 tgatactatt tatctgccaa aagaacgtct tattgataaa attgaacaaa tttcaattgc
     2401 tgatttggtt gcagaagcga ttattcgtat tcatgaaaaa cgtccgttgt cacctttatt
     2461 tgagatgggc aattaaactt aacgaagcct gagataatag atctcgggct ttctgacttg
     2521 aataaaatgt aagggtaatg ttgtattaat tattgtggga tgaactatgc aattctaaag
     2581 gattttgggt ataataagaa agataacaac agtttattgt aaactaagat aaaaggtaag
     2641 agaaaaatac gacgaggtaa tatgcaacta acagaatcac taggcattgt tctttttaat
     2701 aggaattatc gagaagatga taaattagtc aaaatattta ctgaagtagc aggtaagcag
     2761 atgtttttcg tgaaacatat tagtcgttcc aaaatgtcct caatcattca accactaacg
     2821 attgctgatt ttattttcaa gttaaatgat acaggcttgt cttatgttgt tgactatagt
     2881 aacgttaaca cttatcggta tattaataat gatatttttc gattagccta tgctagttat
     2941 gtcttagcat tagctgatgc tgcgattgca gataatgaat cagattcgca tttgtttacg
     3001 tttttgaaaa aaacacttga tttgatggaa gagggcctag attatgaaat tttgacaaat
     3061 atttttgaaa ttcagatatt agatcgtttt ggtattagtc taaactttca tgagtgtgcc
     3121 atttgtcatc gcactgattt accgcttgat ttttcccatc gtttttcagc tgtactttgt
     3181 tctgaacatt attacaaaga caaccgacgt aatcatttag atccaaatgt tatctacttg
     3241 ttgagtcgat ttcaaaaaat cacatttgat gatttgagaa ctatttcatt gaataaagac
     3301 atcaaaaaga agcttcgtca gttcattgat gagttgtatc acgactatgt aggaatcaaa
     3361 ttaaaaagta aaacattcat tgataattta gttaagtggg gagatattat gaaatgatag
     3421 ggcctctttc gtttatggga attggtttca gaatatgcta taataaaaat actattaata
     3481 gattgtgtaa gaacacaaga tataattaaa ggagtggaaa tgaagagaat tgcaatagat
     3541 gctatgggtg gagataacgc tcctaaagct attgttgagg gtgttaatca agcaatagaa
     3601 gcattttcag atatcgaaat tcaactttac ggtgatcaga caaagattaa ctcctatctt
     3661 attcaatcag atcgtgttgc tattattcat acagatgaaa aaattatgtc agatgatgaa
     3721 cctgcaaaag ctgttcgccg taaaaagaag gcttcaatgg ttttagcagc taaggcagtg
     3781 aaagaaggaa aagcagatgc cattatttca gcaggaaata caggtgctct tttagctgta
     3841 ggtttgtttg ttgtggggcg tatcaaggga gttgatcgtc caggattatt atcaactatt
     3901 cccacagtaa ccggattagg atttgatatg ttggatcttg gagctaatgc tgaaaatacg
     3961 gcaaaacatt tacatcaata tgctatttta ggctctttct atgctaagaa tgtacgtggg
     4021 attgctaatc cacgtgttgg tctattaaac aatggtacag aagaaacaaa aggagatccc
     4081 cttcgtaagg ccacttatga acttttaaca gcagataata caatatcttt tgttggtaat
     4141 gtcgaggcgc gagaacttat gtcaggtgtt gcagatgtta ttgtatcaga tggtttcacg
     4201 ggaaacgcag tgttgaaatc aatagaagga acagctatta gcattatggg gcaactgaaa
     4261 cagataatta atagcggcgg tattatgact aaaattggag ctagtctact taaaagtagt
     4321 ctttacgaga tgaagaagac tcttgactac tctagtgctg gaggtgcagt tttatttggt
     4381 ttaaaggcac ctgttgtaaa gtctcatggt tctagtgatg taaaagctat tttttcaacg
     4441 ataaaacaag tacgtacgat gctagacact aacgtggtcg gacaattagt agaagaattt
     4501 gctaaggaga ctcaagtaaa tgactagaca ggagattttt gaaaggctga ttaacttaat
     4561 tcagaagcaa agaagctatt tgagtgtagc tattacagaa caaacacatt taaaaaatga
     4621 tttagcggtt gactctattg aactagttga atttattatt aatgttgaag atgaatttca
     4681 tattgctatt cctgatgaag atgttgagga tatggtattt atgagagacg ttttagatta
     4741 tttagttcag cgtttgactt agttagaata ataaaaagag cgtaagctct ttttattatt
     4801 ctttaaaaac gaatcttttt ttaaaaaaac ttataaacgt aaataatatc ttgaatattt
     4861 ttatagagta tgttactctt aaatgaaaac agaaagaaag gcgaataatc aagtgactaa
     4921 ccagcttatt tataaaggaa aagcgaaaga tatttatagt acaaaagatg aaaatgtgat
     4981 tagaacggtc tataaagacc aagctactat gttgaatgga gctcgtaagg aaactattga
     5041 tggcaaagga gcactaaata atcagatttc atctcttatt tttgagaaat taaataaggc
     5101 tggtgtggtg acacattata ttgagcaaat ttcaaaaaac gaacaattga ataaaaaagt
     5161 tgatattatt ccacttgagg tggtgttacg gaatgtgaca gcaggctcat tttcaaaacg
     5221 ttttggagtg gaagaagggc gcgttcttga aacgccaatt gtggaatttt actacaaaaa
     5281 tgatgatctg aatgatcctt ttatcaatga tgagcatgtg aagtttttgg gtattgttaa
     5341 tgatgaggag attgcttatc tgaaaggaga gactcgccgt attaatgaac tcttgaaagg
     5401 ttggtttgct cagattgggc ttaacttgat tgacttcaag ttggagttcg gatttgatca
     5461 agaaggtaca attatcttag cagatgaatt ttcgcctgat aactgtcgcc tatgggataa
     5521 gaatggtaac catatggaca aggatgtttt tagaagagac cttggcaacc tgacggatgt
     5581 ctatcaagtt gtacttgaga agttgatagc attgtaacta gaagaggaag gaattgaatc
     5641 cgttcgggaa actccgaaaa aaagatggaa cttactgaaa tctcaatttc agatgtcctc
     5701 ctattttcca gtcgctccct tgtcggactt ggtatcttat atgaataaac gtatttttgt
     5761 tgagaaaaag gctgactttg gtattaaatc ggctagcctt gtgaaagagt tgacgcataa
     5821 tctacaactg acttctttga aggctttgcg tattgtgcag gtctatgatg tcttcaattt
     5881 ggctgaggat ttgctggcgc gtgctgagaa gcatattttc tctgagcagg tgacagactg
     5941 tcttttgacg gaaactgaaa tcactgcgga gcttgataag gttgccttct ttgccattga
     6001 gtcgcttcct ggtcaatttg accaacgtgc tgctagttcg caagaagctt tgctattatt
     6061 tggaagtgac agtcaggtta aggtcaatac agcccagctt tacttggtca ataaggatat
     6121 tacagaagca gagcttgaag ccgttaagaa ctatcttttg aaccctgttg attcgcgttt
     6181 caaggacatt actttgccgc ttgaagagca ggctttctct gtgtctgata agacgatccc
     6241 taatcttgat ttctttgaaa attatcaagc tgacgatttt acggcctata aggcagagca
     6301 gggcttggct atggaggtcg atgaccttct cttcatccaa gattatttca aatcaatcgg
     6361 acgtgtgcca actgagactg agttgaaagt tttggatact tactggtcag accactgccg
     6421 tcacacaacc tttgaaactg aattgaagaa cattgatttt tcagcttcta aattccaaaa
     6481 acaattgcag acaacttatg acaaatatat cgccatgcgt gatgagcttg gtcgttctga
     6541 aaagccacaa acacttatgg atatggcgac tatttttggt cgttatgagc gtgccaacgg
     6601 tcgtctggac gatatggaag tctcagatga aatcaatgcc tgctcagttg agattgaagt
     6661 agatgttgat ggtgtgaaag agccttggct cctcatgttt aagaacgaga ctcacaatca
     6721 cccaacagaa attgagccat ttggtggagc ggcgacttgt atcggtggtg ctattcgtga
     6781 cccattgtca gggcgttcat acgtttatca ggctatgcgt atttcaggcg caggcgatat
     6841 cacgactccg attgcggaaa tacgtgctgg taaattgcca caacaagtta tttctaaaac
     6901 tgcggcgcac ggctattctt catatggtaa ccaaattggg cttgcgacaa cttatgtgcg
     6961 cgagtacttc caccctggct ttgtagccaa acgtatggag cttggagctg tggttggtgc
     7021 tgcacctaag gaaaatgtgg ttcgtgaaaa accagaagca ggcgatgtgg tcatcttgct
     7081 cggtggtaaa acaggtcgtg atggtgtcgg tggtgcgaca ggttcatcta aggttcaaac
     7141 ggttgaatct gtggaaacag ctggcgcaga ggtacaaaaa gggaatgcca ttgaagaacg
     7201 taagattcaa cgtcttttcc gtgatggcaa tgtcactcgt cttattaaga aatcaaatga
     7261 cttcggtgca ggtggtgtct gtgttgccat cggtgaattg gctgacggtc ttgaaatcga
     7321 tttggacaag gtgcctctta aataccaagg tcttaatggt actgaaattg caatctcaga
     7381 atctcaagag cgtatgtcag tcgttgttcg tccaaatgat gtggatgcct tcatcgcagc
     7441 ctgcaacaag gaaaatatcg atgcagtcgt tgttgcgacc gttactgaaa aaccaaatct
     7501 tgtcatgact tggaatggcg aaatcatcgt tgatttggaa cgccgtttcc ttgataccaa
     7561 tggtgtccgt gtcgttgttg atgctaaagt cgttgacaag gacttgacag ttccagaagc
     7621 acgcacaaca tcagcagaga cacttgaagc agatacgctt aaggtcttgt ctgacctcaa
     7681 ccacgctagt caaaaaggtc ttcaaactat ctttgactca tctgttggtc gttcaaccgt
     7741 taaccaccca atcggtggtc gttaccaaat cacaccgaca gaaagttctg ttcaaaaatt
     7801 gccagttcaa catggtgtga caacaactgc atctgttatg gctcaaggtt acaatcctta
     7861 tattgcagag tggtcacctt atcacggtgc tgcctatgct gtcattgaag cgacagctcg
     7921 cttggtagca acgggtgctg actggtctcg tgcacgtttc tcttaccaag agtactttga
     7981 gcgtatggat aaacaggcag agcgttttgg tcagccagta tcagctcttc ttggttctat
     8041 tgaggctcag attcaacttg gtttgccatc aatcggcggt aaggactcta tgtctggtac
     8101 tttcgaagac ttgacagtac caccaacctt ggtagctttc ggcgtgacaa cagcggacag
     8161 ccgcaaggtt ctctctcctg agtttaaagc ggctggcgaa aacatttact atatcccagg
     8221 tcaagctatt tcagaagata ttgattttga ccttatcaag gataacttta gccagtttga
     8281 agctattcaa gctcaacata agattacagc tgcctcagcc gctaaatacg gtggtgtcct
     8341 agaaagtctt gctctcatga cttttggtaa ccgtatcggt gcttctgttg aaattgcaga
     8401 gcttgacagc agcttgacag ctcaactcgg aggttttgtc tttacatcag ctgaggaaat
     8461 tgctgacgcg gtgaaaatcg gtcaaactca ggcagacttt acagtcactg tcaatggaaa
     8521 tgaccttgct ggcgctagcc ttctagcagc cttcgaaggc aaattggaag aggtttaccc
     8581 aacagaattt gaacagacag atgttcttga agaagttcct gctgtggtat cagatactgt
     8641 tatcaaggct aaggaaacaa ttgaaaaacc agtggtttac attcctgtct tccctggtac
     8701 caactcagaa tacgattcag ctaaggcctt tgaacaggtt ggagctagtg tcaacttggt
     8761 accatttgta accttgaatg aggttgctat tgctgagtca gttgacacta tggttgctaa
     8821 tattgctaag gcaaatatca tcttctttgc tggaggtttc tcagcagcgg atgaaccaga
     8881 tgggtctgct aagtttatcg tcaatatctt gcttaacgag aaggtccgcg cagctattga
     8941 cagcttcatc gaaaaaggtg gccttatcat cggtatctgt aatggtttcc aagcccttgt
     9001 taaatcaggt cttcttccat acggaaactt cgaggaagct ggtgagacaa gtccaactct
     9061 cttctataac gatgctaatc agcatgttgc caagatggtt gagactcgta tcgcaaatac
     9121 caactcacct tggttggcag gagttgaggt ctgcgatatt catgccattc cagtttcaca
     9181 tggtgaaggt aaatttgttg tcagcgcttc tgaatttgca gagctaagag acaatggtca
     9241 aatctggagc caatatgtgg actttgacgg acaaccatct atggattcta aatacaatcc
     9301 aaacggctct gtcaatgcca tcgaagggat taccagcaag aatggtcaaa tcatcggtaa
     9361 gatgggacac tcagaacgct gggaagacgg actcttccaa aatatccctg gtaacaaaga
     9421 ccaaaccctc tttgcaagtg ctgtaaaata ctttacaggg aagtaaaaag gttcagtgaa
     9481 cctttttagc cctcgccttg aattagtgaa gggcgaggtt agaaagaatc tcgcttaatt
     9541 tttgagaaat agtaaacacg ggcgataagt tgtgcgaaaa actttctatt ttcgctttac
     9601 ttgacagcct ttgtatcgag gtaaaaatga catacgaagt aaaatctcta aatgaagaat
     9661 gtggagtctt tggtatctgg ggacatcctc aggcagctca agtcacttac tttgggcttc
     9721 atagccttca acatcgcggt caagaaggag ctggtattgt ttcaaatgac aatgggaaac
     9781 tctatggtta tcgaaatgtt gggctccttt ctgaagtttt taagaatcaa tctgaattag
     9841 ataatttaac tgggaatgcg gctattggac atgttcggta tgctactgca ggttctgcag
     9901 atattcgcaa tattcagcct tttctttata aatttcatga cgggcaattt gctttatgcc
     9961 ataatggtaa tttgacaaat gctatttcct taaggaaaga attagaaaag caaggtgcaa
    10021 ttttcaatgc ctcctcagat actgaaattt taatgcattt gattcgtcga agccataacc
    10081 caaatttcat aggaaaggta aaagaagctc taaatacagt aaagggtggc tttgcctatc
    10141 tactgatgac agaaaataaa ctcattgctg ctcttgaccc taatgccttt cgtcctttgt
    10201 caattggaca aatgcaaaat ggtgcctggg ttatttccag tgagacctgt gcttttgagg
    10261 tggtaggcgc aaaatgggtt agagatgttg aacctggcga agttattctt atagacgata
    10321 gtggtattca atgtaatcgt tatactgatg aaacgcaact ggcaatttgt tcgatggaat
    10381 atgtctattt tgcaaggccg gattcaacta tacatggtgt taatgttcat acggctcgaa
    10441 aaaatatggg aaagcatctt gcacaagaat ttaaacagga tgctgatatt gtaattggtg
    10501 tcccaaattc gtccttatcg gctgctatgg gctttgctga agaatccgga ttaccaaatg
    10561 agatgggtct tgtaaaaaat cagtatacgc agcgaacctt tattcaaccg acacaagaat
    10621 taagggaaca aggtgttcga atgaaactat cagcggtatc tggtgttgtc aaaggaaagc
    10681 gcgttgttat gattgatgac tcaattgtaa gaggaacgac ttctagaagg attgtcggat
    10741 tattaagaga agcaggagct agtgaagtac atgttgctat agctagtcca gaattaaagt
    10801 atccttgttt ttatggtatt gatattcaaa caagacgaga attaatttca gcaaatcacg
    10861 ctgctgacga agtgtgtgat attattggcg cagatagtct gacctatctc tcactagatg
    10921 ggttgattga atcaattgga ctcgaaacaa aagcaccaaa tggtggttta tgcgtagctt
    10981 actttgatgg acattatcca acaccgcttt atgattatga agaagaatac ctcagaagtt
    11041 tagaagaaaa aacaagtttt tatattcaaa aagtgaaata agctctgcta attatataag
    11101 gagaaaacat gtctgaaaaa aatgcttatg caaaatctgg tgttgatgtt gaagctggtt
    11161 atgaagtggt tgaaagaata aaaaaacacg ttgctcgtac agaacgtgcg ggagtcatgg
    11221 gagctctagg tggctttggt gggatgtttg acttgagtaa aacaggagtt agagagcctg
    11281 ttttggtctc agggacagac ggtgttggca caaaactcat gcttgctatc aagtacgaca
    11341 agcacgacac aatcggtcaa gactgtgttg ccatgtgtgt caatgatatt attgcagcag
    11401 gtgctgagcc cctttacttc cttgactacg tagcgacagg aaaaaataat ccagtcaaat
    11461 ttgaagaagt tgtttctggc gttgcagaag gttgtgttca agcaggagca gcactcattg
    11521 gaggtgagac cgctgaaatg cctgggatgt atggcgaaga tgattatgac cttgctggct
    11581 ttgctgttgg tgtggctgaa aaatctcagc tcatcgacgg ttcaaaagta aaggaaggcg
    11641 atattctttt gggacttgct tcaagtggta tccattcaaa cggttattct ttggtacgtc
    11701 gtgtctttgc tgactatact ggtaaagagc tgcttccaga acttgaagga aaacaactta
    11761 aggatgtcct tcttgagcca actcgtattt atgttagagc agctctgcca ttaatcaagg
    11821 aagaactagt caacggtatc ggccacatca caggtggtgg ctttatcgag aatgttcctc
    11881 gtatgtttgc agatgatttg gctgcggaaa tcgatgagga caaggtgcca gtgcttccga
    11941 ttttcaaggc gcttgaaaaa tatggtgaca tcaagcacga agaaatgttt gaaatcttca
    12001 atatgggtgt cggtcttatg ctagctgtta gtcctgaaaa tgttaaccgc gtcaaagagc
    12061 tcttggatga accagtttat gaaatcggtc gtatcatcaa gaaagcagac gatagtgtgg
    12121 tgattaaata agtcactaaa ttttataaga aaggagtgtt tagttagttt gcctaactga
    12181 acacgggatt aaatttctag gaaaaaagat aaaatgactt agacgcaagc gtcgttgttc
    12241 gttttcctat ttttctacga aatttttcgg caagccgaat catccctttg tatcgaatat
    12301 gaaaatcgct gtttttgctt ctggtaatgg ttccaacttt caggtcatag cagagcagtt
    12361 tccagttagt tttgtctttt cagatcatcg tgatgcctat gttttagagc gtgctcagaa
    12421 tttagccatt ccaagcttcg cttttgaact caaggagttt gagaataagg cggcttacga
    12481 gcaagccatc gttgatttgt tggacaaaca cgagattgat ttggtctgtc taacgggcta
    12541 tatgaagatt gttggagaaa ccttactctt ggcctatgag gggcgtatta tcaatattca
    12601 cccagcctac ctgcctgaat ttccaggtgc ccacggtatc gaggatgctt gggaagctgg
    12661 tgttgaccag tctggcgtga ccatccactg ggttgactct ggtgtggata ccggtcaggt
    12721 catccaacaa gtgcgcgtgc cacgcctagc agacgatagc ctagaaagct ttgaaacccg
    12781 tatccatgaa accgaatatc aactctaccc agctgtctta gatagcttgg gagtggagag
    12841 gaaagtaatc tagcctttat cttaaaattt taggtaaagt taggaaagat agtaaagaag
    12901 aattaacgtt ccaaaaagaa aggaattgaa cccgtctgga aggcacagaa aaaagataaa
    12961 catctcctag gcgcaagcgt cttcgtcgag tttcctattt ttccttggcc ttctagtcgg
    13021 acttggtatc ttaaatatga ctaaacgtgc tttaatctca gtgtctgaca agtcaggaat
    13081 tgttgacttt gcaaaagaat tgaaaaactt gggttgggat attatctcaa ctggtgggac
    13141 taaggttgcc cttgataatg ctggcgttga gaccattgcc atcgacgatg tgactggatt
    13201 cccagagatg atggacggtc gtgttaagac cctccaccca aacattcacg gtgggctttt
    13261 ggctcgtcgc gacgctgaca gccaccttca ggctgctaag gacaacaata tcgagctgat
    13321 tgacctcgtg gttgtcaacc tctatccctt caaggagact atccttcgtc cagacataac
    13381 ctatgatttg gcggtggaaa acatcgacat cggcggtcca tcaatgcttc gctcagccgc
    13441 taaaaatcac gctagcgtga ccgttgtggt tgacccagcg gattatgcga ctgttttggg
    13501 agaattggct gacgctggtc agacgacatt tgaaacgcgt caacgcttgg cagctaaggt
    13561 ctttcgtcac acagcagcct acgacgcttt gattgctgag tacttcacaa ctcaagtggg
    13621 agaggctaag cctgaaaaat taaccatcac ttacgacctt aaacaggcta tgcgttacgg
    13681 agaaaatcca caacaagacg ctgatttcta tcaaaaagcc ttgccaacag actactcaat
    13741 tgcttctgct aaacagctca acggaaaaga attgtccttc aataatatcc gtgatgccga
    13801 tgcagcaatc cgtattatcc gtgatttcaa agatcgtcca actgttgttg tcctcaaaca
    13861 catgaaccca tgtggtatcg gacaggctga tgatattgag acagcttggg attacgctta
    13921 tgaagctgac ccagtttcaa tctttggtgg aattgtcgtc cttaaccgtg aagttgacgc
    13981 agcgacagct aagaagatgc accctatctt cttggaaatc atcatcgcac catcatactc
    14041 agaagaagcg ctagctattc tcacaaataa aaagaaaaac ttgcgaatcc ttgagttgcc
    14101 gtttgatgcc caagctgcca gcgaagtgga agctgagtac actggcgtag ttggtggact
    14161 tttggtgcaa aaccaagacg ttgtggctga aaatccatct gactggcaag tggtgacaga
    14221 ccgccaacca acagaacaag aggcgactgc ccttgagttt gcctggaagg ctatcaagta
    14281 tgttaagtct aacgggatta ttattactaa cgatcacatg acgcttggac tcggtgcagg
    14341 tcaaaccaac cgtgtcggct cagtcaagat tgctatcgag caggctaaag accaccttga
    14401 cggtgccgtt ctagcatcag atgccttctt cccatttgcg gacaacattg aagaaatcgc
    14461 tgccgcaggg atcaaagcaa tcatccaacc aggtggttca gttcgtgacc aagactctat
    14521 tgacgccgca aacaaacatg gcttgaccat gatcttcaca ggtgtgagac attttaggca
    14581 ttaataaaaa aatgtggtct aattaaaacc acatttttta ttaaaagaaa atataagtta
    14641 actataattt gttagcttta tcagcattta cccatgttct acgagatccg atttgaacat
    14701 aaataccatt acttggttga tcaattttta atactttata actaccagtg acggtaaaat
    14761 attcacccac acggagaatt tgatctccta aaacttttcc ttggttatct gtttcatcta
    14821 atggtgtggg atcaatccag tttagtggag ttgggtctcc tccggctaat tctttattaa
    14881 cgatcaaatt attaacaagc tgatctacac gaaaaacgcc agggaaggta acagtatcac
    14941 cgatcttaat ggaaggtttt gtattgtcat tttgaaccac agactgtgcg ggctctttaa
    15001 tgggaatata gcgtcggttt ccagaaaaac tgaggtagct aagccatgta taacctccag
    15061 cagtcacgac tttatcgtaa taaacagatt gacctgcttc atagtaagca agatcagggc
    15121 tatcgatact ggtttgtcct ttgactggta atctggttgt aaagtgataa gttccagagg
    15181 ggtcaaatga agcttgagaa atgtgtttta gttgtcttgg gtaggaatga cttgtctgag
    15241 atgataagtc tttaaaatgg atataaccac ttacctgaga ttttggaatt tgacgcttat
    15301 ggtatctttc agggccttgt ccagcgttgt aattatactc ttcgatagtg acagtgtctc
    15361 cacggatatc agctacccat gctacatgac cgtaagcagc atttgactga taagcgtttt
    15421 tatcaaacca agcgatagcc cctatgcttg gtgtcttatt cacaggataa ccctgatttt
    15481 tcgcgatatg tccccacgtg caggcattac cgtagccttt aggtaactga aaaccattag
    15541 cagagcttaa acgaaaagct gcaaaagaag tgcattggcg gatatacatg ttccacgaat
    15601 cgattccatt gccttttttc cacttactcg gatagttatc gcctaaaaca gctgcatgaa
    15661 caagattttc ctgttgcgaa ataagtgtag atggcatagt aggtactaga ccattaaaac
    15721 ctaaaaggat tactcctgag accaaaaaac gatgaaattt tttcattaat tacctcctgt
    15781 aacttattat tcgaaagcaa gaaacaaaaa atgttatttt tagatgatta ttttgaaaat
    15841 tggctttact tgatattaaa taactgtttg attggctaat agagtgttcc ttatttcaag
    15901 aattgtggtc tactatcaca tttttacaat gtttcaatta ttgataacta atacattatg
    15961 taaaaaagcg aacgtttatg atataatatc taattataat acgaaagagg tggatgtttt
    16021 gaaattactt gttgttggtt caggtggtcg tgaacatgcg attgctaaga agttgttagc
    16081 atctaagggt gtggatcagg tttttgtggc acctggtaat gatggtatga ccttggatgg
    16141 tctggacttg gtgaatatag tagtttccga acattccagg ttgattgcct ttgctaagga
    16201 gaatgagatt tcttgggcct ttattggtcc tgatgatgcg ctagcagctg gtatcgttga
    16261 tgatttcaac agtgctggac tcagagcttt tggtccaaca aaggcagcag cggagctaga
    16321 gtggtcaaaa gactttgcca aggaaatcat ggtcaaatac aatgtcccaa cagcagccta
    16381 tggcacattt tcagactttg aaaaagccaa agcctacatc gaagagcagg gcgtacctat
    16441 cgtggtcaag gctgatggct tggcgctagg taagggtgtg gtcgtggctg aaaccgttga
    16501 gcaggcggta gaggcggcgc aagagatgct tctggacaat aagtttggcg attcaggagc
    16561 gcgtgtggtt atcgaggaat tcttggatgg cgaggagttt tccctctttg cctttgttaa
    16621 tggtgataag ttctacatca tgccgacagc tcaggatcac aagcgtgcct ttgacggaga
    16681 caaggggcca aacactggtg gtatgggtgc ctatgcgcca gttcctcatc tacctcagag
    16741 cgtggtagac acagcggttg agacgatcgt taggcctgtc cttgagggca tggttgccga
    16801 agggcgtcct tatctaggtg tcctctatgt ggggcttatc ctgacagctg atggacctaa
    16861 ggttatcgag ttcaactcac gtttcggtga ccctgaaact cagattatcc tccctcgcct
    16921 gacttccgat ttcgctcaga atattgacga tatcatgatg ggcattgagc cttacatcac
    16981 ttggcagaag gacggtgtga ctttgggtgt tgtcgttgcc tcagaaggct atccactcga
    17041 ttatgagaaa ggtgtgccac tgcctgaaaa gaccgacggc gatatcatca cctactatgc
    17101 cggagctaag tttgtggaaa atagcgagct acttctctca aacggaggac gtgtctatat
    17161 gcttgtcacc acagaagaca gcgtcaaagc agggcaggac aaaatctata cccagctagc
    17221 ccaacaagac acaacaggtc tcttctaccg aaatgacatc ggaagcaaag ctataagaga
    17281 ataagactaa ccattcaaat attagcgtca gcaatcaacg accgaaggtc gctccaaaaa
    17341 gaaagaagaa aggaactgaa cacgggacta atttcctagg aaaaaaataa aactacctgg
    17401 acacaagcgt catcgttagt tttctgcgtc gtaggcgtct gatgctaaag cacctagtcg
    17461 ccctgacgtg ggttcgtctt cgaaatcaaa gatttcggac ttaccgcata tttttctacg
    17521 gaaattttcg acaagtcgaa acgccccttt gtatcttaat tatgaaaact ccaattattt
    17581 ctattatcat gggctccaaa tctgactggg caaccatgca aaaaacggct gaagttctag
    17641 acaactttgg cattgcttac gagaagaaag tcgtctctgc tcaccgtacg ccagacctca
    17701 tgttcaagca tgctgaggaa gcacgtggtc gtggcatcaa aatcatcatc gcaggagcag
    17761 gtggggcagc tcacttgcct ggtatggtgg cagctaaaac aaccctgcct gttatcggtg
    17821 tgcctgtcaa atcacgtgcc ctttcaggtt tggattcact ctattcgatt gtgcagatgc
    17881 ctggcggtgt gcctgtggca accatggcta tcggagaagc gggagcgact aacgctgccc
    17941 tgacagccct ccgtattctc tccatcgagg atcaaaatct ggctgatgcg ctagctcatt
    18001 tccatgagga acaaggaaaa atcgcagagg agtcaagtgg tgaactcatt taagaccatt
    18061 gggattatcg gtggtggtca gctggggcag atgatggcca ttgcggccat ctatatgggc
    18121 cacaaggtca tcacgctgga tcctactaac gactgccctg cctcccgcgt tagcgaggta
    18181 attgtggcgc cttacgatga tgttgaggct ttgggacaat tggctgcgcg ttgcgatgtg
    18241 ttgacttatg agtttgagaa tgttgatgcg gacggtttgg atgccgttgt gtcagcttgt
    18301 cagctaccgc aggggaccga tctgctccgc atttcccaaa accgtatctt tgaaaaagac
    18361 tttctggcaa ataaggctgg tgtgactgtt gctccctata aggtggtgat gtctagcctt
    18421 gacctagagg ggcttgattt taccaagacc tatgtcctca agacggcgac aggtggttat
    18481 gacggtcatg ggcaaaaggt tatccgctca gcagaagatt tgccagaggc gcagcaatta
    18541 gctaactcag ctcagtgtgt cttggaagag tttgtcaatt tcgaccttga aatctcagtc
    18601 atcgtgtctg gaaacggaga ggatgtgacg gtctttcccg ttcaggaaaa tatccactgc
    18661 aataatatcc tgtcaaaaac tatcgtgcca gctcgtatct cagatcaact ggctgataag
    18721 gctaagaaaa tggcggtgca gattgccaag aaactccagc tgtcaggaac tctctgtgtg
    18781 gaaatgtttg cgaccgcaga tgatatcatt gtcaatgaaa ttgccccacg tccccacaac
    18841 tcagggcact actctatcga agcctgcgac ttttcacaat ttgacaccca cattttgggc
    18901 gtgctaggag cgccgctccc aactatccac ctccatgctc cagccgtcat gctcaatgtc
    18961 ctcggacaac acgtccagca ggcaattgac tatgttgccc aaaaccctag cgcccacctc
    19021 cacatgtatg gtaaactaga agcgaaacat aaccgcaaaa tgggacatgt gacactattt
    19081 gcagaagatg cggatgaggt ggaggagttt taggatgtat ctaaagta
//
LOCUS       DAUNLR010000032        18812 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUNLR010000032 DAUNLR010000000
VERSION     DAUNLR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18812
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.032"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            404..721
                     /locus_tag="VLL59_001162"
     CDS             404..721
                     /locus_tag="VLL59_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HER6509288.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
     gene            845..2743
                     /gene="mnmG"
                     /locus_tag="VLL59_001163"
     CDS             845..2743
                     /gene="mnmG"
                     /locus_tag="VLL59_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HER6509289.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            2833..4809
                     /locus_tag="VLL59_001164"
     CDS             2833..4809
                     /locus_tag="VLL59_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HER6509290.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNGLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKCLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            4806..5258
                     /gene="rplI"
                     /locus_tag="VLL59_001165"
     CDS             4806..5258
                     /gene="rplI"
                     /locus_tag="VLL59_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HER6509291.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKELTAEIKLAITEA"
     gene            5288..6655
                     /gene="dnaB"
                     /locus_tag="VLL59_001166"
     CDS             5288..6655
                     /gene="dnaB"
                     /locus_tag="VLL59_001166"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HER6509292.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            6672..6944
                     /locus_tag="VLL59_001167"
     CDS             6672..6944
                     /locus_tag="VLL59_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HER6509293.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            7673..8284
                     /gene="rpsD"
                     /locus_tag="VLL59_001168"
     CDS             7673..8284
                     /gene="rpsD"
                     /locus_tag="VLL59_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HER6509294.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(8438..8971)
                     /locus_tag="VLL59_001169"
     CDS             complement(8438..8971)
                     /locus_tag="VLL59_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HER6509295.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFRTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            9106..11379
                     /locus_tag="VLL59_001170"
     CDS             9106..11379
                     /locus_tag="VLL59_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HER6509296.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRAGKSLTIGNDMVDKLSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNSEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASTGSQALDSGAKTAQMGSQMLSDNLAGLSSASWQFQQGT
                     NRLTSGLTAYTAGVSQVKDGLGQLSTDMPVYLNGVSRLSQGASQLNQGLSQLTQSTTL
                     SDDKAKRIQSLEVGLPVLNQGIQQLNANLSTMQVPKLNTDELGNNLAAIAQAAQQLLV
                     KEAAAHKEQLAVLQATSAYQSLTAEQQGELTAALTQTDKGEAVAPAQTILRSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIASQSNQALPGASSALSELSMGLSKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADS
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWNWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(11495..12574)
                     /locus_tag="VLL59_001171"
     CDS             complement(11495..12574)
                     /locus_tag="VLL59_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HER6509297.1"
                     /translation="MKNISRKCFMTSVVCIILGGILLGAGYATGGLQDIKHQTAPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKLIDPIVTTVTGKTLSLSQKP
                     KDVVITGGIEILGFTLNNSRQEKNYRSITITVPEKTSLNEVKASNVPHTTLSNLTVQD
                     MQFDGNLTLLHTKVKKATITGMLEATKSQLTNLELKADYSFSNLTDSSVENGTISLGN
                     GQLTTKDTTLKAVNIQSLHPGGIEAERTTLENVTFTVSKSKEEEENDYYDNDAIFTAH
                     ALTLKGTNTITGGDIDVDITLTKAKAIAYRARTENGKVSLGSQLTPAKIGKESTSDVI
                     SYVAENKAATGNLTVNLNKGDITIK"
     gene            complement(12571..13158)
                     /locus_tag="VLL59_001172"
     CDS             complement(12571..13158)
                     /locus_tag="VLL59_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HER6509298.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATAILRFSGRAFVAFIKWISNKKGAQA"
     gene            complement(13145..13471)
                     /locus_tag="VLL59_001173"
     CDS             complement(13145..13471)
                     /locus_tag="VLL59_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HER6509299.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
     gene            13678..14319
                     /locus_tag="VLL59_001174"
     CDS             13678..14319
                     /locus_tag="VLL59_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HER6509300.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEIRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWESIQPNEEVDKVFTVPLRQLLVTDPVYYHLEATPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEKTIWGMTAQFTKCLTDILNDESIAKKNPLDIEKSKGR"
     gene            complement(14366..15208)
                     /locus_tag="VLL59_001175"
     CDS             complement(14366..15208)
                     /locus_tag="VLL59_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HER6509301.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVIVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKVDWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAFVLFALGIWLGLWMSQLE
                     EKYK"
     gene            15625..15669
                     /locus_tag="VLL59_001176"
                     /pseudo
     CDS             15625..15669
                     /locus_tag="VLL59_001176"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15676..15957
                     /locus_tag="VLL59_001177"
     CDS             15676..15957
                     /locus_tag="VLL59_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HER6509302.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRSALRIERFKKTYDVQTYR"
     gene            complement(16421..17023)
                     /locus_tag="VLL59_001178"
     CDS             complement(16421..17023)
                     /locus_tag="VLL59_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509303.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(17020..17772)
                     /locus_tag="VLL59_001179"
     CDS             complement(17020..17772)
                     /locus_tag="VLL59_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HER6509304.1"
                     /translation="MAIPDLDKFSSSLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGRQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            complement(17838..18611)
                     /locus_tag="VLL59_001180"
     CDS             complement(17838..18611)
                     /locus_tag="VLL59_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509305.1"
                     /translation="MLYLNTQTDSDYKEIIFGDIAKFVENMFYHYFSSILFRDLETVD
                     KRMYSFSDDDLISIQSSCLRLSKTFANFNIQRKNFLASDETEMDTFHKKDDIDITVGE
                     KSYNLARSFRTSTINELTVFNFEEMFDIIWLMLGDNLIKSFEVNVCGILFELDGNGIP
                     STFRQENIDPLINKWWYDNVSTEIIPNLIKKLKENPLFNIGFLVDDILERMYKENIPK
                     SYLTSVPLVISKKARSTLSIKSNGSQKIDKSKFAQILSL"
BASE COUNT         6080 a         3134 c         3727 g         5871 t
ORIGIN      
        1 acttagaaac aacggtatct gtattttact actttagaag atatcaaaaa atcgtatgat
       61 aatactgatg acatttttat ttctcgcctc gctagattag acatagtgat acttttgtaa
      121 tcattttaaa aacattacaa tagattgaca gagatgtaaa aacattgaca ttactgtaaa
      181 ggtctgtgat gaaatcaata ttgacaatca ctaatcattt ttttaaaata gataataaca
      241 atcggaatga tggtcaaagc tcatgaaagt tgtaggtttt tttgtcctgc aatcttctag
      301 ggttttggcc ctttttatgg tttagctcta gaattgagat ggctaatagg actgggattt
      361 agaatcacta gaggtcagat aactttagtt tacgagctag tgcttgattg ttagaaatgg
      421 taagaatttt ttaactagag atgcagctga ccaatattac accattggtg gtacaagttt
      481 ggtaggtgaa aaaacgcatg aaactgtttt acgtgaaacc ttagaggaag ttggtattcg
      541 aactaaggtt aatcaactgg cttttgtggt tgagaatcat tttgatatcg atgatgtttt
      601 ctggcataat attgaatttc attatttggt aagcccctta gaagacccta aactagaaat
      661 gatagagaat gcaagcgaca ggtttgtgaa tggattccaa tcaatcaact ggatcaaatg
      721 aatcttgttc ctgagttttt acaaaccgag ttggctaaat ggccaggaca tattgtccgc
      781 attgaaggct aaactaaagc gtatgatttt aaatgaatag actgaaataa aggattttaa
      841 aaaaatgaca catgaattta cagaaagcta tgacgtcatt gtcataggtg caggtcatgc
      901 tggtgttgaa gccagtttgg ccactagtcg tatgggttgt aaaactttat tggcaacaat
      961 caaccttgat atgttggctt ttatgccgtg taatccttct attggaggat ctgccaaagg
     1021 gatagtggtt agagagattg atgctcttgg cggcgaaatg ggtaaaaata ttgataaaac
     1081 ctatatccag atgaaaatgc ttaatacagg taagggacca gctgtacgcg ctctccgagc
     1141 tcaagcagat aaatccctgt atgcgcgtga aatgaaacat acggttgaaa aacaggctaa
     1201 tttgactctt cgccaaacga tgattgatga tattctagtt gaagatggac gagttgtagg
     1261 tgttttaaca gccacaggac aaaaatttgc agctaaggca gttgtagtga caacaggaac
     1321 agctctgcgt ggcgaaatta ttttaggaga actcaaatat tcttctgggc ctaataatag
     1381 tttggcatca gtaactttag cagataattt aaaaaaactt ggcttagaaa ttggcagatt
     1441 caaaacagga acgcctcctc gtgtcaaagc atcttctatt aattacgatc aaacggaaat
     1501 tcagccaggt gatgacaaac ctaatcattt ttcatttatg tcaaaagatg ctgagtatct
     1561 caaagatcaa attccctgct ggttgactta tacgaatcaa actagtcatg atatcattaa
     1621 tcagaacctt tacagagcac cgatgttttc tggcattgtt aaaggtgtag gccctcgtta
     1681 ctgcccatct attgaagata agattgttcg ctttgctgat aaagaacgtc atcaactttt
     1741 cttagagcca gaggggcgtg atacagaaga agtgtatgtt caagggttgt caacgagcct
     1801 tccagaagat gtccaaaaag atttgattca ttcgatcaaa ggacttgaaa aggctgaaat
     1861 gatgcgcact ggttatgcta ttgaatatga tattgtttta cctcaccagc tacgtgccac
     1921 acttgaaacc aagctaattt caggactctt tacggctggg caaactaatg gaacttctgg
     1981 gtatgaagag gctgctggcc aaggacttat tgctggaatc aatgctgctt tgaaagttca
     2041 aggtaagcca gaacttattt tgaaacggag cgatgcttat attggcgtta tgattgacga
     2101 tttggttacc aaaggaacct tggaacctta tcgattgttg acatcgcgag ctgagtatcg
     2161 tttgatttta cgtcatgaca acgctgatat gcgtttgaca gagattggtc gcgacattgg
     2221 gttggttgat gatgagcgtt ggaaggcctt cgaaattaag aaaaaccaat ttgataacga
     2281 attaaaacgt ctgaacagta tcaaattaaa accagtaaaa gcaaccaacg atcgtgtgca
     2341 ggaacttggt tttaaaccat tgacggatgc tatgacagct aaagaattta tgcgtcgccc
     2401 agaaattgat tatgcgactg cagtctcttt tgttggtcct gcggctgaag atttagatgc
     2461 taaaatcatt gaacttttag aaacagaaat caagtacgaa ggctatattc gcaaagcttt
     2521 agatcaggtt gctaagatga aacgcatgga agaaaaacgt attcctgcaa atattgattg
     2581 ggatgctatt gattctattg caactgaggc gcgtcagaaa tttaagaaaa ttaatcctga
     2641 aacaattgga caagctagtc gtatttcagg agtcaatcct gcggacatca gtatcttgat
     2701 gatttattta gaaggaaacg gaaaagctca tcgaaaatat taaatggaaa tgaaattgta
     2761 atctcaaagc aagtggaagc tctgtatttc agggcttttt tatggtataa tgtgtgctta
     2821 agaggttata agatgaaaaa atttcgtttt gaaaccattc atttgattat gatgggattg
     2881 attttatttg gactactggc actttgtgtc agtattatgc aatcaaaaat attaatatta
     2941 ttagctattt ttctcgtttt gctatttgtt gttgctcttt tatggtatca aaaagaagct
     3001 tatcaattat cagacttagc tcatattgag ctcttaaatg aacaaacaga agataaccta
     3061 aaaacgctac ttgataatat gcctgttgga gtagttcaat ttgatcaaga gaccaacgct
     3121 gtagaatggt ataatcctta tgcagaatta atttttacaa ctgaagaggg ttttatacaa
     3181 aacggtttga ttcagcaaat tattacggaa aaacgtcgtg aagatatttc tcaaacattt
     3241 gaagtttctg gtaataaata cacttcttat attgatgtat catcaggaat tttttatttt
     3301 tttgatagct ttgtgggaaa caggcaatta gctgatgcta gtatgttaag accggttgtt
     3361 ggcattattt cggttgataa ttatgatgat atcactgatg atttatcaga tgcagatacc
     3421 tcaaaaatta attcatttgt agctaacttc attgatgagt ttatggagtc aaaacggatt
     3481 ttttaccgtc gtgttaatat ggatcgctac tatttcttta cagactttaa aacattaaat
     3541 gatttgatgg ataataaatt ttctgtctta gaagagtttc gtaaagaagc tcaagatgct
     3601 cagcgccctt taacactcag cataggaatt tcttttggtg aagaaaatca tagccagatt
     3661 ggacaggtag ctcttgagaa tcttaatatt gcgcttgttc gtggtggtga tcagattgtc
     3721 attcgtgaaa atgcggatca tacgaatcca atctatttcg ggggagggtc tgtttctaca
     3781 gttaaacgtt caagaacacg tacccgtgct atgatgacag ctatttcaga tcgaatcaag
     3841 atggtggaca atgtttttat tgttggacat aggaaacttg atatggatgc actaggttca
     3901 gctgttggta tgcaattttt cgcaggtaac attattgaaa atagttttgc cgtttacaat
     3961 ccagatgaga tgagtccaga tattgaaagg gctattgagc gattgcaggc tgacggaaag
     4021 actcgtctaa tcagtgtttc tcaagcaatg ggtttagtga ctccaagatc acttttagta
     4081 atggttgacc attctaagat atctttaaca ctttctaaag aattttatga acagtttcaa
     4141 aatgttattg tagttgatca tcacagaaga gatgatgatt ttcctgataa tgctatctta
     4201 acttttattg aaagtggagc aagtagtgct gcggagctcg tcactgagtt aattcaattt
     4261 caaaatgcta aaaaatgttt aaataagatc caagccagtg ttttaatggc aggtattatg
     4321 cttgatacta aaaatttttc tacgcgagtg acaagtcgta cctttgatgt cgctagttac
     4381 ttaagaagca aaggaagtga tagtgttgaa attcaaaata tatccgcaac agattttgaa
     4441 gaatataagc aaataaatga aattatttta caaggagaac gtcttggtga cagtatcatt
     4501 gtagctgcag gagaaaaaaa tcatctttat agcaatgtta ttgctagtaa agctgcagat
     4561 acgatactgt caatggctca cgttgaggct agctttgtat tagttgaaac agcttctcat
     4621 aagattgcta tttcagctag aagtcgtagt aaaatcaatg ttcaacgtgt gatggaaaaa
     4681 ttaggtggag gaggccactt taatcttgct gcctgtcagt taacggatat cagtcttccc
     4741 caagcgaagc acttattatt gaaaactatt aatatgacaa tgaaagaaac aggagaagta
     4801 gaatcatgaa agttattttt ttagcagatg taaaaggaaa aggtaaaaaa ggagaaatca
     4861 aagaggtccc aacaggctat gctcaaaatt tccttattaa gaaaaattta gctaaagaag
     4921 caactagtca aagcatcggt gaattaaaag gaaaacaaaa agctgaagaa aaagctcaag
     4981 ctgaaatatt agcagaagct caagctgtca aggctgtttt ggatgaggac aaaacacgtg
     5041 ttcaatttca agaaaaagtt ggtccagatg gacgtacatt tggttccatc acagctaaaa
     5101 agatttcaga agaattgcaa aagcaatttg gtgtaaaagt tgataaacgt catattgttt
     5161 tagatcatcc tatccgcgcc attggtctaa ttgaagttcc tgtgaaatta cataaggaac
     5221 taacagctga gattaaattg gctatcacag aagcataata taaaaaacat cacaagattt
     5281 ggaggttatg aggttgcctg aagtagctga attacgagtt caaccccaag atttactagc
     5341 agagcaatct gttcttgggt caatctttat ctcacctgat aagctgattg cagtgagaga
     5401 atttatcagt ccagacgatt tttataagta cgctcataaa attatctttc gggcaatgat
     5461 tactctcagc gatcgtaatg atgccattga tgcaaccact ataagaacaa tcctagatga
     5521 tcaagatgat ctgcaaagta ttggtggctt atcctatatt gttgaactag ttaatagtgt
     5581 cccaactagt gctaatgcag aatattatgc taaaattgta gctgagaaag ctatgttgcg
     5641 tgatattatt gctaggttga cagaatctgt caacctagct tatgatgaaa ttttaaaacc
     5701 agaagaggtt atcgctggag ttgagagagc tttaattgaa ctcaatgaac atagtaatcg
     5761 tagtgggttt cgcaaaattt cagatgtgtt aaaagttaat tacgaggctt tagaagcacg
     5821 ttctaagcag acttcaaatg ttacaggttt accaactggt tttagagacc ttgacaagat
     5881 tacaacaggt ttacacccag atcaattagt tattttagct gctcggccag cagtggggaa
     5941 gactgccttt gttcttaata ttgcgcaaaa tgtggggact aagcaaaaaa agactgttgc
     6001 tattttttct ttggaaatgg gtgctgaaag tttagtagat cgcatgcttg cagcagaagg
     6061 aatggttgat tcgcacagtt taagaacagg gcaactcaca gatcaggact ggaataatgt
     6121 aacaattgct cagggagctt tggcagaagc accgatttat attgacgata cgcccgggat
     6181 taaaattact gaaatccgcg caagatcacg gaaattgtct caagaagtgg atggtggttt
     6241 aggtctcatt gtaattgact acttacagtt gattacagga actaaacccg aaaatcgtca
     6301 gcaagaggtt tcagatattt caagacagct taaaatccta gctaaagaat tgaaagtacc
     6361 agttattgcc ctaagccagc tttctcgtgg cgttgagcaa aggcaagata aacgaccagt
     6421 tttatcagat attcgtgaat caggatctat tgagcaggat gccgatattg tagccttctt
     6481 ataccgggac gattattacc gtaaagaagg tgatgatgct gaagaagctg ttgaagataa
     6541 cacaattgaa gttatcctcg agaaaaatag agctggggcg cgtggaacag tcaaactgat
     6601 gttccaaaaa gaatacaaca aattctcaag tatagcccag tttgaagaaa gataagaaag
     6661 agagacaaaa aatgagcgat gcatttacag atgttgcaaa aatgaaaaaa attaaagagg
     6721 acataagagc ccatgaagga cagttagtag aattaaccct tgagaatgga cggaaacggg
     6781 aaaaaaataa aattggtagg cttattgaag tttacagttc actctttatc attgagtata
     6841 gtgatagctc tgatactcca ggagcaattg ataattctta tgtcgaatca tacacctatt
     6901 cagatatttt gacagaaaaa acattaattc gttatttaga ttgatttttg cctcatagag
     6961 gctttttctt tacaataaat tgatataatt attagcgata gaagattatt ctgcctgtat
     7021 tctttttatt ttgaaaaaat tcctataaaa gataatattt ttaggttaga ttgaaggaaa
     7081 aaagaggtct tcaccatggt taagcaaatg atcttagtat taaggttaaa agattatcgt
     7141 gaaataaagt tttgacacaa gtgtaattga tagaggaact tgaagtatcc ggtaaaacta
     7201 tcttgaagtg aaaaaacgag taaacctccc ctgataaata caatatacta gccatttcag
     7261 agcaattaag agtttccagt gaagtgcttt tgatagagag ctaagaaaaa acagtcaagg
     7321 tttaagaact gcaaattagc atttaaatta ttttttgtta atgacagttg tctttattac
     7381 cataactata acttcttata atatagtctt cttaattcat cagtggtggt tcgtctcata
     7441 tctgacctta aaatattaaa ctgatcatca gatgatagat agactgactt tacaaaacaa
     7501 ctttcttatg gtaaactgtt ctttgtgcga aataacagca gaaaaatatg aagctcgtca
     7561 acaggtggtt atctattcaa gtaacctttg ctgtttaggc gaaaaccccc tgcacgaatc
     7621 aggatttttt aaaccgttat ttcctcaaaa aatttagagg aggacatgta atatgtcacg
     7681 ttatactggt ccatcatgga aacaatcacg tcgccttggt ttatcactta caggcacagg
     7741 taaagaattg gcacgtcgta actacgttcc tggtcaacac ggtccaaaca accgtagcaa
     7801 actctcagaa tatggtttgc agttagctga gaaacaaaaa cttcgtttct catacggttt
     7861 aggtgaaaaa caattccgta acttgttcgt tcaagctaca aaaatcaaag aaggaactct
     7921 tggtttcaac tttatggttc ttttagaacg tcgtcttgac aacgttgttt accgtctagg
     7981 tttagcaact actcgtcgtc aagcacgtca attcgttaac cacggtcaca tccttgttga
     8041 cggtaaacgc gttgatatcc cttcataccg cgttgatcca ggtcaagtga tttcagttcg
     8101 cgaaaaatca atgaaagtac ctgcaatcct tgaagctgtt gaagctactc ttggacgtcc
     8161 agctttcgta tcatttgatg ctgaaaaact tgaaggttca ttgactcgcc ttccagaacg
     8221 cgatgaaatt aacccagaaa tcaatgaagc acttgtcgtt gaattctata acaaaatgct
     8281 ttaattttaa gattaaactt acaaaaagcc tatttaatag gctttttttg tatctcataa
     8341 caaatctatt ctgatccctt cattttatta tggcttctaa aaaagttatc actaaggctg
     8401 atgacttgta aaatgatact ttcgtaagag ttactattta ggtactcgta agcattttga
     8461 gaacgaattg tgtcatttct tgaggtgatt cttttttacc tttagcaatc caactttgac
     8521 agacaccaaa aaaagcatgg gctaagtaga tactttggta ttctttttcc gtttgagata
     8581 actcttcggt gcggaacttg tcctgtaaat cagtagtgat gagtaggcga actttattga
     8641 tgataaaggc ctgtatttct ttggtaccgt tagcagacaa aagggaagag agaagctgtt
     8701 ctctttggag aaattcaaat acttcaagga aggcttgttc tttattttga tattttttct
     8761 caaaaatata ttctaatttg tgaaaaaagg tttgctgata atagtcaatc atttcatatt
     8821 tatctttata gtgtgtgtaa aaactagagc gactaattcc agctctttta gataatttaa
     8881 ctgtggtaat atcgtcaaaa ctttcggttt ttagtaacat aaccattgct tttaaaattg
     8941 cttgtttcgt attttcttta cggttgacca tctaccatct ctccttttga acacttttag
     9001 acataatgtc caaaagtgaa attttttctc ttgtaaattt aaatttaaat tgtataatat
     9061 attttatcat aatttttgaa caccatgtcc attttaggag aaaatatgtt agaagaattg
     9121 aaaacactta ttaaaaatcc aaaattaatg attacaatga ttggtgtggc cctagtgcct
     9181 gccttatata atttatcctt tctaggctca atgtgggatc cttatggtcg ggtcaatgac
     9241 cttcccattg ctgttgttaa tcatgataag cctgcaaaga gagctggtaa gtcattgaca
     9301 attgggaatg atatggtgga caagctgtct aaaagtaaag atttagagta tcattttgtc
     9361 tcagctaagc aagctcaaga gggacttaag gaaggtgatt attatatggt tattacttta
     9421 cccgaagatc tttctcaacg ggcagcaacc ttattaaatt ctgaacccca aaaattaact
     9481 atccgttacc aaacgagtaa aggacatgga atggtcgctg ctaagatggg ggaaacagcg
     9541 atggctaagc tgaaagagtc tgtttcacaa aacattacga agacttatac ctcagcagtt
     9601 tttagcagta tgacagacct ccaatcagga ttaaaagaag cctcaactgg tagtcaagca
     9661 ttggattcag gagcgaagac agcccaaatg ggtagtcaaa tgctctcaga taacttagca
     9721 ggtttatcta gtgctagttg gcaatttcaa caaggaacta atcgtttaac ttcaggatta
     9781 acggcctata cagctggtgt tagtcaagta aaggacggtc tagggcagct ctcaaccgat
     9841 atgccagttt acctgaatgg ggtttctcgg ttatcacaag gagcttctca acttaatcag
     9901 ggtctttcac agttgacaca atcaacaaca ctttctgatg ataaagctaa aagaatccaa
     9961 tctttggagg taggattacc agttttaaat caaggtattc agcaactaaa tgcaaatctc
    10021 tcaacgatgc aggtaccaaa acttaatacc gatgagttag ggaataactt ggctgccatt
    10081 gctcaagctg cgcaacagtt acttgttaaa gaagctgctg ctcacaagga acaactagca
    10141 gtcttacaag ccactagcgc ttatcagtca ctaactgctg agcaacaagg ggaattaact
    10201 gctgctctta cccaaactga taagggtgaa gctgtggctc ctgctcaaac gattttaagg
    10261 tctgttcaaa ctttgtcaac aagtttacag tctctctctc aagaagatca gtcaaaacag
    10321 ttggagcaac ttaaggaagc tgttgcacag attgcgagtc agtctaacca ggctttacct
    10381 ggagcgagtt ctgcattatc tgagttgtca atggggttat caaaggtaaa tggtagctta
    10441 aatcaacaag ttctaccagg aagtaatcaa ttgacaacag gattagcaca attaaacagg
    10501 tataatactg ccattggttc tggggtaata aaactctcag aaggtgccaa tgccttgtca
    10561 tccaagtccg gagaattact agatggtagc catcaattat cagaaggtgc tactaaacta
    10621 gctgatagta gttctcaatt gagtcagggt ggtcatcaat taacgagcgg attgactgaa
    10681 ttatcaacag gattgtcaac cttaaatggt tccttagcca aagcctctca gcagttatcg
    10741 cttgtttctg tgactgataa aaatgctaaa gctgtcgcaa aacctcttgt gttaaatgag
    10801 aaagacaaag atggtgttaa gacgaatggg atcgggatgg caccttatat gattgctgtt
    10861 tctctaatgg ttgtggccct ttcaaccaac gtcatttttg ctaattcttt atctggtcgt
    10921 ccggtcaaag ataaatggaa ttgggctaaa caaaaatttg ttattaatgg ttttatttcg
    10981 actatgggat ctattgttct ctacttagct attcaattat tagggtttga agcccgttat
    11041 ggtatggaaa ccttaggatt tattatgcta agtggttgga cgtttatggc tcttgtcaca
    11101 gctttggtcg gttgggatga tcgatatggc tcttttgctt ctttggtcat gttattgctt
    11161 caggttggct cttcaggtgg ctcttacccc attgagttaa gtggagcatt tttccaaaag
    11221 ttacatcctt tcttaccaat gacttatgtg gtatctggtt tacgacaaac catttcatta
    11281 tcaggtcata ttggagtaga agtgaaagtc ttaactggtt tcttactggc atttatggta
    11341 ttagcactac tcatttatcg tcccaagaaa acagtctaaa taaaataacc tcaaaaaaaa
    11401 cagcatctaa ggcagttaca ctagatgctg ttttttgtct tattttgaca ataacttgac
    11461 aatttctgtc aagtttttta ttgtcttgtt aagatcattt gatagtaatg tctcccttat
    11521 tgagattaac cgttaaattt ccagtagctg ctttattctc agccacataa gaaataacat
    11581 ctgaagttga ttccttacca atcttagctg gtgtcagctg tgagccaagg gagactttac
    11641 cattttcggt ccttgctctg taggcgatgg cctttgcttt tgtcaaggtt atgtcaacat
    11701 caatatcacc accagtaata gtattagtcc ctttaagggt aagggcatga gcggtgaaga
    11761 tagcatcatt gtcatagtag tcgttctcct cttcttcttt gcttttagaa acagtgaagg
    11821 tcacattttc aagggttgtt ctctcggctt ctataccacc agggtgtaat gattgaatat
    11881 tgacagcttt tagagtggta tctttagtag ttagttgtcc atttcctaag ctgatggtcc
    11941 cattttccac actagaatca gtcaggtttg aaaaagaata gtcagctttt aactcgagat
    12001 ttgttaactg acttttagtg gcttccaaca taccagtgat agtagctttc ttgactttgg
    12061 tatgtaaaag agtaagattg ccatcgaatt gcatatcttg gacagttaga tttgacaaag
    12121 tggtatgtgg gacattgctt gccttaactt cattgaggct agttttttca ggaacagtaa
    12181 tggtaataga acggtagttc ttctcttgac gactattatt gagagtaaaa cctaaaattt
    12241 caattccacc agtgatgaca acgtctttag gtttttgcga aagagatagg gtcttacctg
    12301 ttactgttgt gacgatagga tcaataagtt taggatgtgt gtaataggtc actgttggtc
    12361 tttgaacggg tcctgtctct actgtaatag ttgaggcaga actgtcaata tcaagagcag
    12421 ttatttggtc aaatgttttg atgacctttt tgggagctgt ttggtgttta atgtcctgaa
    12481 gtcctccagt tgcatagcca gcccctagaa gaatgcctcc tagaataata cataccacac
    12541 tggtcataaa gcatttgcgt gagatatttt tcatgcttga gctcctttct tattactgat
    12601 ccacttaata aaggcaacaa aagcccgtcc tgaaaaacga aggattgctg tggcaataat
    12661 ccaaataaga agaccaccac caaaacacaa caaggcgctg ccgattccca tagcttgtgc
    12721 aggaatagat gagccaatca aggtcaagct ttcaaacagg gtcactcctg cgacaagaat
    12781 acctgcaagc ccaaaaatgt aggcggcaaa gatagctgtg agcccgagca ttaggcaggc
    12841 aataataaag agaatcaacg ccagcaatac gggtaaagca atcggagcag caaagaggga
    12901 caaaatggtt aatccaatga ttgttgcccg atttttggga gttttctcgg gagttgccaa
    12961 gtgttttcct agaacatttg aaatgatttc actggcagct tccttaggat ttcctaaatc
    13021 gtcgataacc tggctttctt tgtcaggacc agcttcatca aaatattcaa tataatattc
    13081 catcgcttca tggtagtctt ctctaggtag tttgcgcaag tatttatcta attctgctag
    13141 atactcagtc cttgtcatgt cttaagctcc cttcaataat accgtctaag gcaaatttat
    13201 agctctgcca ttcttttttt agaaaaatca gctgtgctct ccccgaagaa gtgacagcat
    13261 aatatttacg ctttcgtccc tgatgttctt gactataagt tgtcaaaaaa cctgccttct
    13321 ccaatttttt aagaatagga tagagggtgg attctttgat attagccact agtttaatgg
    13381 tttgactaat atcgtaaccg taagaatcat ttttttcgac aatggctaaa atcagaaatt
    13441 caatcaaggt agccgatact ggaaaataca ttttaggctc cttccatata taaaaatttt
    13501 atatataatt attttacata tttagtataa gcttagtttt ttgatatgtc aatattttat
    13561 atataaaaaa ataatatata tatcaaaaat aactaactag gagtaataag ttgaccaaga
    13621 agctaggatt ggttatgatg aagataagat taacagaaag agaaattagg gaaggctatg
    13681 aaggacttat taaaacagta tcaggcaaaa ccactaggag aggagaagcg gtacgccgta
    13741 tttttacctc ttattcttgt caatgatgac tggcatgtct tatatgaaat cagaagtcag
    13801 catatttcac aaccggggga agtttctttc ccagggggac aagtagaaaa tcaggagaca
    13861 cttcaagaag ctgctatccg agaaacagtt gaggaattga ctgttgatgc gtcccagatc
    13921 cagctatggg gtgaaattga ttatttagta cagtcttcta gaactattca ttgtttcgtt
    13981 ggtcaattag tcgttgatga ctgggaaagc atacagccta acgaagaagt tgacaaggtc
    14041 tttacagtac ctttacgtca gctacttgtc actgatcctg tctattatca tttagaagcc
    14101 actcctattg agacaacgga ttttcctttt gaccgtattc gtaatgggaa atactaccaa
    14161 tttagtcaag agtaccgtag tattccgttt tatgaaaatc tagaaaaaac catatgggga
    14221 atgactgccc agtttactaa gtgtttaacc gatattctaa atgatgaatc aattgcaaag
    14281 aaaaacccct tagatattga aaaatctaag gggagataga gcactagttt attggcgtca
    14341 actttttgtc aacaacctgt aaaggttatt tgtatttttc ttctaattga ctcatccaaa
    14401 gtccgagcca aataccaaga gcaaataaca caaaggccat aagccaggtt aagatacctg
    14461 catgactgta ggaaatggat tcgggactac tactatttgg aataagaatt aatagcgtgc
    14521 tggataatac aataccaatg ataaagtggt aaacttttga atgatggtgc tgtaaagcat
    14581 aatccatact tttagaaaaa gccaagatgg ctaggactcc tccgatagca ataggtaaga
    14641 aagtccctaa taaatccaaa gatttgaatc ctattaacat aggaccatag agtcctaaga
    14701 taagtaagag atttgacggg cttagtccag ggaccagtac tcctaaagca attaaggcac
    14761 ctgctaaaat aaaggttaaa aagttagctg gtaaggtacc gattaagtca tttaagaagt
    14821 aaagacctag tcctgaaata acaaaggtaa ggactagcca tagccagtca actttgtctc
    14881 tttgagactg cttggttgac tccttaatca gactaggaat agtgccgaca atagcgccag
    14941 caaatcccca taagacgata acttgatagt gcttaagcaa aaactcaacg gggaaagaaa
    15001 agagagcaat acctaaaata ccaccaattc ctactggtaa gaaaaataag acattttcaa
    15061 taaagttatc cctcatatga gctaaaaagg aaatcattcg ctcatagatt cctaaaatgg
    15121 ctgcgagaac accaccggat acaccaggta aaataaaacc tagtgcaata atcatgcctt
    15181 taaaaactct tgaaataaat gaaaccattg ttgcctcctg aaaagaatga ttttattgta
    15241 tcataaattt aaagaattgc tgacacaaag ctgcatatcc ctactaaaat aattgttcct
    15301 aataaataat acattataaa taatacattc aattttgaag atattttcct taaacaccat
    15361 gtctttgtga tcaagtcaag tttgattgtc aaagttgtaa ataaatttta caaagactgt
    15421 aaaccttacg ataattatca aaaagataaa cgaaaaaaag cttaggtcaa agacttttga
    15481 tagtaaactt attgaagaag gattatagta gctattaaaa aggagattta ttatgggctt
    15541 taaaaaccag ttaccttatt attgaaaaaa attacagatg tcacaagaag agcttgctga
    15601 aatgatgtat gtttcaagaa gactatctca aactgggaaa acggtaaaag ctatccagac
    15661 ctgcaaaatc ttttgatgtt aagtaagtcc ttacaggttc ctttagagca actaatagca
    15721 gaagatatcc caaaaatgac tttaattatt aaggatgagg agattaaaca atgtgatagg
    15781 aatacgcata ttatgttatt tgggacactc ctaattgcta tcagtattta tcctataatg
    15841 tcttggttag gttggtgggg atatggtccg gttgctatct tatggttgat aatcatgcgt
    15901 agcgccttaa gaattgagcg atttaaaaag acatatgatg ttcagactta ccgataactt
    15961 gaagctatag caaagggtga gagcttagat cagattgata agattaaaga aaaagcaaaa
    16021 tatccttatc aaaaagcatg gattgttatt gcgtacacag gattgacagt gttaataacc
    16081 ctactctcta ttttgttttt tcatttgttt ttttaaacac gaaaaaagcc tttgaaacgt
    16141 tcatttcata ggcttttctc atctcaatta ttttacttct gtaaaggtta agtattttct
    16201 attttagctg ttataaacct tattgtatca atatttattg atagttgctt aataaaaggt
    16261 agagtagtta ttgcgttagt tcagcaatct tttcaagata aataaatacc cacagcttct
    16321 aactttcgtt gtcgtagtaa ccccaatagg tcatgataga taagaatata aaaaaggggc
    16381 tgtctggctt ttgcttaacg caagccacag ccccaaggaa ttaacgcttt tgaccaataa
    16441 accacaattg gttacgaact cgaacaggag aagagaaata atagtctgtg tgttggatga
    16501 caatctcttc tttcagttgt actcccgtat cctttaggat tttttgcccc tgttggtctc
    16561 taggaacttt tagaaataca gtaatggcat cttttcgtat atctacgata cacttacgta
    16621 cagctcggtt aaacccgtta tggattggat tgatagtggt aacggtctgg tgttcaaagt
    16681 tgcttacctt ctgtactcgt tcacgctgga aaaggaagtg tcttaataga aaggtgcgat
    16741 aaatagattg gcagtagttc ccaaggctat ctgtattcaa gcgttgtatc atctttaatc
    16801 cagataataa ggctagaagt aaagaaataa gagcgaatcc ataacataca gaactaatgg
    16861 tatcagtaac gtttttaacc gtatccagat tgacaaatgt gacggtagat aattgaactg
    16921 aaacaagatt gaacagccaa ccgaacacat agcagattgg agcaataagc agtaagtata
    16981 atatgagatt gaagcttctc atgaagtagg ttttagtggt cataggatac ctcgcttagt
    17041 atagtaggtt ggacagagta agggtagaac ttgataggag tgttcattat cgacaacttg
    17101 aatgatacct gttccgtgtc ctgttggaat gacaatcccc tctggatcta ggtctggaaa
    17161 taagaattga gtggttttct gattgatatt tccaatttgc aataatacgt ttagctgttc
    17221 cctcactgaa atgggaatag tgttatggtc aaaacgctgt cttcccaaga atagatggat
    17281 tttagtagca tgtcccaaca aggcaatttg tgatagtagg gagaaaaaag cttctttgat
    17341 attcttattg actccctctg atagagcgag gacttcatca ataacaatag ttagatgggt
    17401 aaattgatga ttgggattat catacaagat agcttgtcgt ttctgaatga gagttgcaca
    17461 ctggtttaat tgttcattga cttgtgaaac gaaatcagat tttgaatggt tttctactgg
    17521 gtggataacg gcaattttat tttctcttgc ccattggcta ggggtatcga attttgggtc
    17581 aatgataatt aggccggaca taggtttcag gacactcaag aagtaagtga gagcgtacgg
    17641 tttcccagaa cctgaatttc cagcaatagc ccagtgactc cccttatcta aattgagttc
    17701 gaagtgcttt atgacaggaa ttttcccctg ttgtaagcta gatgaaaatt tatctaaatc
    17761 aggaatcgcc aagcgttctg aaatcccctt tctccaaggg aagaataatc cacgttgaat
    17821 gtgtaagtca tccgtctcta aagggacaaa atctgtgcaa attttgattt atctattttt
    17881 tgacttccgt ttgacttaat cgataaagtt gaccttgctt ttttggaaat aactaacggg
    17941 acggacgtaa ggtaagattt tgggatattt tctttataca ttcgttctag aatatcatca
    18001 accaggaatc cgatattaaa tagtggattt tctttgagtt tttttattag gttagggata
    18061 atttctgtcg aaacattatc ataccaccat ttattgatga ggggatcaat gttttcttgc
    18121 ctaaatgttg agggtatgcc atttccgtct aattcaaata ggataccaca gacattaact
    18181 tcaaatgatt taattaaatt atcccctaac atcaaccaaa taatatcaaa catttcttca
    18241 aaattaaaga cagtcaattc attgatggta ctggttctaa aacttctagc gaggttataa
    18301 cttttttcac caacagtaat gtcaatgtca tctttcttgt gaaaagtatc catttcagtt
    18361 tcatcagaag ccaaaaaatt ttttctttga atattgaaat ttgcgaatgt cttggaaagt
    18421 ctaagacagc tggattgtat tgaaattaag tcatcgtccg aaaaagaata cattctttta
    18481 tctacagttt ccaaatctct aaataaaata gagctgaagt agtggtaaaa catattttca
    18541 acaaacttgg caatatctcc aaaaataatt tctttatagt ccgagtcggt ttgagtattc
    18601 aaataaagca atattgaagc ggtaacttgt cgctttccct tttcaacttg gctaacttga
    18661 cctgcattac ctaggtcact ttactttaaa ttatactttt ttcttaaaca tttgatacga
    18721 gtaggtattt cttgtgagta attttcatca aaaaatttca tagataagcc ccctataaac
    18781 atggaaaagt ggtaaaaata gttgttatcc ta
//
LOCUS       DAUNLR010000033        18249 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUNLR010000033 DAUNLR010000000
VERSION     DAUNLR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18249
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.033"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            44..1093
                     /locus_tag="VLL59_001181"
     CDS             44..1093
                     /locus_tag="VLL59_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HER6509306.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCEDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVKPGDNVCIVGAGPVGLAALLTVQFFSPANIIMVDLSQNRLEAAKTFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            complement(1176..2342)
                     /locus_tag="VLL59_001182"
     CDS             complement(1176..2342)
                     /locus_tag="VLL59_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HER6509307.1"
                     /translation="MENQLGQLALEQAKTFGGKLEVQPKVDIKTKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLQKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYLDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(2374..3705)
                     /locus_tag="VLL59_001183"
     CDS             complement(2374..3705)
                     /locus_tag="VLL59_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HER6509308.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSENMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKDVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            3866..5407
                     /locus_tag="VLL59_001184"
     CDS             3866..5407
                     /locus_tag="VLL59_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6509309.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCFLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            5388..6053
                     /locus_tag="VLL59_001185"
                     /pseudo
     CDS             5388..6053
                     /locus_tag="VLL59_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(6108..7181)
                     /locus_tag="VLL59_001186"
     CDS             complement(6108..7181)
                     /locus_tag="VLL59_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HER6509310.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFIFQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPIHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(7174..7950)
                     /locus_tag="VLL59_001187"
     CDS             complement(7174..7950)
                     /locus_tag="VLL59_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509311.1"
                     /translation="MKKFANLYLASIFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            complement(7947..8741)
                     /locus_tag="VLL59_001188"
     CDS             complement(7947..8741)
                     /locus_tag="VLL59_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509312.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGSQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            complement(8725..9879)
                     /locus_tag="VLL59_001189"
     CDS             complement(8725..9879)
                     /locus_tag="VLL59_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509313.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGFENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEEGLINAIEEERNEENL"
     gene            complement(9925..10812)
                     /gene="murB"
                     /locus_tag="VLL59_001190"
     CDS             complement(9925..10812)
                     /gene="murB"
                     /locus_tag="VLL59_001190"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HER6509314.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVKLEPEVRIIGENL"
     gene            complement(10962..11462)
                     /gene="folK"
                     /locus_tag="VLL59_001191"
     CDS             complement(10962..11462)
                     /gene="folK"
                     /locus_tag="VLL59_001191"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HER6509315.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            complement(11459..11818)
                     /gene="folB"
                     /locus_tag="VLL59_001192"
     CDS             complement(11459..11818)
                     /gene="folB"
                     /locus_tag="VLL59_001192"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HER6509316.1"
                     /translation="MDKIVLEGCRFYGYHGAYKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            complement(11825..12625)
                     /gene="folP"
                     /locus_tag="VLL59_001193"
     CDS             complement(11825..12625)
                     /gene="folP"
                     /locus_tag="VLL59_001193"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HER6509317.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFIGNRA
                     QAALDAGVPKNNIWIDPGFGFAKSVQQNMELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            complement(12634..13218)
                     /gene="folE"
                     /locus_tag="VLL59_001194"
     CDS             complement(12634..13218)
                     /gene="folE"
                     /locus_tag="VLL59_001194"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HER6509318.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEHHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKQPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            complement(13253..14530)
                     /locus_tag="VLL59_001195"
     CDS             complement(13253..14530)
                     /locus_tag="VLL59_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HER6509319.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYP
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRRYWKKHIEKSVLLTH"
     gene            14862..15824
                     /locus_tag="VLL59_001196"
     CDS             14862..15824
                     /locus_tag="VLL59_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HER6509320.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEMGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            complement(15941..17176)
                     /locus_tag="VLL59_001197"
     CDS             complement(15941..17176)
                     /locus_tag="VLL59_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HER6509321.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKNAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTTTLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDHRYPGSALEEENMLSAQDVAIVTMHLLEDFPEILEITKQTEVDFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRLITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQVKELPISVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKPIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(17439..17843)
                     /locus_tag="VLL59_001198"
     CDS             complement(17439..17843)
                     /locus_tag="VLL59_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HER6509322.1"
                     /translation="MDFEQKFLKVHTTLEKDENGNWYRKDQTKTPAGERLIELDDVTI
                     VVLENWRRNQVVNTDTDFIISRFGEPFCKSTICRVIKHKAQSIGVPVITGKGLRHSYA
                     SYLINVLKKDILYVAKCMGHADKSTTLNTYSH"
BASE COUNT         5734 a         3890 c         3179 g         5446 t
ORIGIN      
        1 aatgaattgg ttgattacct ctcaacctta taaggagtta aatatgaaag cagcaactta
       61 cctttcaacc ggaaatctac agctcataga caaaccaaaa ccagtcatta taaagcctac
      121 agatgctatc gtccagttgg taaaaaccac tatttgtgga actgatttgc atatcttagg
      181 tggggatgtt cccgcatgta aagaaggaac aatccttggt catgaaggaa ttggaattgt
      241 taaggaggtc ggtgatgcgg ttactaactt taaaatcgga gataaagtga ttatttcttg
      301 cgtcacatca tgtcatacct gttattattg taaacgaggc ctttcgtcac attgtgaaga
      361 tggcggttgg attcttggcc atttaattaa tggaacacaa gcagaatatg tccatatccc
      421 acatgcagat ggtagtctct atcatgctcc tgatacgatt gatgatgagg cacttgtcat
      481 gctttctgat attttaccaa cttcatatga aattggtgtc ttgccatcac atgtcaagcc
      541 tggagataat gtttgtattg ttggtgccgg tccagtagga ctcgcagccc tactaaccgt
      601 tcaatttttc tctccagcca atattattat ggttgactta tctcaaaatc gccttgaagc
      661 agctaaaacg tttggagcca cacacacgat ttgttcagga agtagtgaag aagtcaaggc
      721 tatcattgac gatataacca atggacgtgg tgtcgatatt tccatggagt gtgttggtta
      781 tcccgcgaca tttgatattt gtcaaaaaat tatatcagta ggtgggcata ttgctaacgt
      841 tggggttcat gggaaaccag ttgatttcaa cctggatgaa ttatggatta aaaatatcac
      901 cttaaacact ggacttgtta atgccaatac aactgaaatg ctactaaatg tcttgaaaac
      961 tggaaagatt gacgcaacaa gacttattac acatcatttt aaactttcag aagttgaaaa
     1021 agcttatgaa acctttaaac atgctggtgc aaataacgcc ttgaaagtta ttattgataa
     1081 tgatattagc taatcacaaa ataagtagaa gctagaaata tgcttctact tattttgtga
     1141 tttaaagtat aactttctct tttttttcat atattctatg atttaaggac taccgacctg
     1201 acgcttttag cgacaatctc agcgactcct tctttaaagg catctggaat aatattagta
     1261 gtgctcaaag cgtcatctgg gacaagactg gcaatacctt ttgcggcagc aatttgcatc
     1321 tcaacagtaa tggtttttgc ccgtgcatct aatgctcccc taaaaatacc tggaaaggca
     1381 aggacattat taatctggtt aggaaaatca ctgcggccag tacctacaat gtaagccccc
     1441 gcttcaaggg cttcatcaag gtaaatctct ggaatagggt tggccatggc aaaaattact
     1501 gggcgcgctg ccattttact aatccactct gcttttaaga ctcctggtgc tgatacgcca
     1561 atgaagatat ctgctccttc aagagcatct tctaaggtac ctgatttaaa ctcacgatta
     1621 gtgactttcg ctatatccaa atgatgtggc gctaattgag cggcttcttg ttcattgata
     1681 atgccaaatt tatccactac tgtcactttc gtagcacctg ctgctaataa tttacgggta
     1741 atggataatc cagcagatcc accaccgttc accacaatgg atacctcatc aagggatttt
     1801 tgaagaagtt tcaaactatt gaagatggct gctaacacca caatagctgt tccatgctga
     1861 tcgtcatgga aaacaggaat atgacattcc ttaatcaagc gctgctcaat ttcaaaacag
     1921 cggggcgcac taatatcctc taaattaata ccaccaaagg ttggtgcaag cgccttgaca
     1981 atactaataa tttcttcagt atctttggta tctaatacaa tcggaatagc atcgacaccc
     2041 gcaaatgctt taaaaagggc tgcttttcct tccataactg gcatggctgc ttcagggcca
     2101 atatccccca gaccaagaac cgcagtacca tcactgataa cggctactgt atttttcttg
     2161 gtggttaagt catatgctaa tgttttatct tttgcgatgg cagatgacac actcgctaca
     2221 cctggtgtat aggcaatgct caaatcatgt ttagttttaa tgtcaacttt tggttgaact
     2281 tccaatttac cgccgaacgt tttggcttgt tcaagggcaa gttgacctaa ttgattttcc
     2341 ataggaaata cctctctttt ttattggttt ggattaacta aaaataattc ttaaaatagc
     2401 tgtcatagtg ataacggtaa tagccccacc tagacgggta gcgacttggg caaacggcat
     2461 tagattcatg cggtctgcgg tactcaaaat agccacatca cctgttccac ccataccact
     2521 ttgacaagct gaaataatag ctgcttccac tgggttcatg ttaaggaaac gagagacaaa
     2581 aaaaccgaca ctgacaaccg ttaacaccac actaatcacc acaataaaat attgccagct
     2641 aagggtggcc acaacatctt ttaatgggat ataaaggagt ccaagccctg ccattagtgg
     2701 aaaagtaaag ttgctggaaa taaatttata aagttgtttg gcaccatttt gtgtttcttg
     2761 ggggataaca ttcaggtatt tcaagaaggc cgccaagata atcatcaaca ccggtcctgg
     2821 aaaacctgtt aaatgctgta acaagccacc agcaataaaa agtgaacaag ctgttaaaac
     2881 gcctgccccc attaatttaa catctagggc tccagaattg tcttttaggg catcagacat
     2941 attttcgctg tgaccaattt taaccagttg cccttgacca gaataacttg gatgcttctc
     3001 cccaaaacga ttgagcaaag ccgtgcacaa gatagcaaag aaattcccaa taatggtggc
     3061 tggaatcagt tgagccacta attgctcact tccgactcct gtaatggcac tgtaaccaag
     3121 agataagggt aaaatacctt caccaattcc tccagcaagg actggcgtca caacataaaa
     3181 gagggtatgt tgccagtcta atcctaaaat gacgccaacc aaagtcccta cacccattgc
     3241 acaaaccatt ccaagtaaca tgggaataat catccgaaaa agaccttgaa tcaagatttt
     3301 tcgattcatg cctaaaatac taccgcagac caggcaggca atataaaaat aaagaaaatt
     3361 cgcttgcttc atcaagacat tcgtcgcttc taagacattg gggttgagga gattaaaaaa
     3421 aaccaaaatc gaagggacta agagtgataa aatagctggg ccaccaaaat gtttgaggcc
     3481 tggaatggtc gctccaatgg ttcctagtag ccaaccaagg gttaaaataa cagcaaagcc
     3541 acccagcata ttaacaggca actgttggag ccagcctgtg actaaaatta aggtagctaa
     3601 aaccagataa acaggcaagg gaacggagcc tattcgccta ttttgccatg cttttgaatg
     3661 ctcagacaag tctttttgag gcattttctt gcttattgtt tccatgaaac aacctccttt
     3721 agtgataagg ctagtataaa agagaacatg tcaaaagcat agtttattta agttgtttaa
     3781 ctactttaat tttttcaagt tatttaatta atttaagcta gcaggtcatt tcttatcgtg
     3841 ttatactcaa taaagaggag accttatgaa aaaaccacta cgtttatggg ccagtttatc
     3901 gttgattttg gtatctatga ttgttgtcac aacctctcta ttttacggga ttatgctaca
     3961 tgatacgcac caatccatca aaaatcagga aacccatttg ctaacgtcaa ctggaaaaat
     4021 gttagcaagt catcaagcga ttaaagaatt actcctaaac aaccaaccaa atgctaaaac
     4081 aacagcctat accaactcca ttgcctccat ctataacctt gattatgtgg tcgtgatgaa
     4141 catgaaaggg attcgactca cccatcctaa cccgaaaaat atcggaaaac cttttcaagg
     4201 aggtgatgag gaggctgttc tagcaggaaa aaaggttatc tctaccgcca agggcacttt
     4261 aggaaagtca cttcgctatc tagtacctgt gtttgacggt gacaaacaga ttggtgctat
     4321 tgcggttggc attaaactaa ctaccctaaa tgatgtggct ttaacgtcaa aacgcaatta
     4381 taccctgtct ttactccttt gttttcttat tagtttactg gtcaccagtt ttatttcttt
     4441 tcgactcaag cgtcaactgc accagttaga accaagtgaa atttaccagc tctttgaaga
     4501 gcgtaatgcc atgttggatc aaatcgaagc cgccgtattt gtggtagata aagctggtat
     4561 cttacagctc tgcaatcagg ctggacaaaa attaattgct cggaaatgcc agttgggaaa
     4621 acctactggc aacagtttca atcacctctt tcctgatttt ccaaaactta gtttgcaaga
     4681 ggggcatgaa caactctttc ggtatggtga ggaagactac ttgttagcca tttcacccat
     4741 ctgtgtcaaa aacgatcacc gaggccacat tattttcatg cgagaagcag ttaaggctat
     4801 tgataccttg gatcagctag cctataccac tgcctatgct tctgctctac aagcccaaac
     4861 tcataaattc atgaatcaat tgcatgttat ttatggctta gtggatattg cttattatga
     4921 ccaattgaaa atttatttag acagtatttt ggagcccgaa aatgaaattc tcactagctt
     4981 atctgtcctt gttaaggagc ctcttctagc tagttttctc attggagagc aagagaaata
     5041 ccaagaatta aatgtccatc tcaagattga tgttttaagc gagattcctc attctgccac
     5101 caagaatcaa cttaataatg gtttgatgat ttaccgcttt atccatacta atcttctaac
     5161 cacactgaga cccaaatcac tcgttttgag tattcaacat gatcagaatc atttaatcag
     5221 ccattacacc ttgacagaca attggattga tttggagcgg gtacagccta tttttgactt
     5281 accttatttt caacagctct tgaccgatac aaattcccaa ttccatcaac atcaaaccgt
     5341 aaccgagtta cagttctcag tgacaacacc ttatgtagga gggcaacatg aacgttttaa
     5401 tcattgaaga tgatcctatg gtggatttta tccatcgcaa ttacctctaa aaactaaatc
     5461 tttttgatcg cattatatcc agcgactcta tgaaagctgt tcaaagtata cttactgatt
     5521 acgcaattga cctcatttta ctggatattc atattacaga tggcaatggg attcaatttt
     5581 tggagaaatg gcgtgctcag catattcctt gcgaagtcat tattatttca gccgcaaatg
     5641 atgggaatat tatccgagat ggttttcatt taggaattat cgactacctc atcaagccct
     5701 ttacctttga acgctttcaa gaaagcatcc aacagtttgt tacacatcga gaacatttgg
     5761 ccaatcagca actagagcag gcccaaattg accaactgaa atgtttgact agcaaaaaag
     5821 acactaaaaa caaacaattg ttagaaaaag gcttatctga atccactttc cagtggatta
     5881 tggaaaatat taaagccttt gatcaacctt ttactatcca agaattagct tccgcttgtc
     5941 acttatccca tgtctctgtc cgtaaataca ttgcttattt agaagaaaat aagcaactga
     6001 acagccaaca aatttttacc aaggttggcc gcccctatcg cgtgtactgg tgacgtcatc
     6061 tgtcgataca ttaaaaaggc tggagaaata ccagcctttt tgagtgctta tttgcgatac
     6121 attttaaatt ggaggtataa atcattataa atccccaacc atcttgaccc taaattgtca
     6181 taaacttcca attttttgat aatgtcatct gttggataaa aagcaggatc attttttatc
     6241 tcatctggaa gtaaggcctt ggctttttta tttggtgtcg cataaccaat atatgcagca
     6301 ttttgcgcag cattttcagg acgattgata aagttcaaaa aagcataagc ttctttttcg
     6361 tgtttcatgg tttttggtag taccaaatta tcaaaccaaa ggttagaccc ttctgaaggc
     6421 acgatgtagt gaaggtgttc gttactatct aacatctcac tggcttcacc agaaaaggta
     6481 attccaatag cagcgtcacc ttgaatcatg tagcctttca tctcatctgc tacaatggct
     6541 ttaacattcg gcgtcaactg ctgcagtttt ctctcggctg cctgcaactg ctctagattt
     6601 ttagaattca cactataacc aaaagttgtt aaaccaaccc ctagcatttc acgcgctcca
     6661 tcaatcagca taatactatt tttatattct ggacgccaca gatcttccca gtgtataggc
     6721 gccttatcaa ctaattgatc attataaaca atcccaacgg ttccccagaa ataaggcaaa
     6781 gaatagtcgt tttgtgggtc aaagcttttc cctaaaaatt ctttcccgat attatccatg
     6841 ccaactaatt ttgacttatc aagcttattg agtaggtttt ctttgatcat tttatcaatg
     6901 gtgtaatcac taggaacagc aatgtcataa gtggttccgc cctgcttgat tttagtgtac
     6961 atggcttcat tggaatcgaa agtttcatac tgcacttcaa tgcccgtttc tttggtgaat
     7021 tttttgagca aagctggatc aatgtaatct ccccagttat aaataactaa tttatccgat
     7081 tgactaccag aacccgattt tttctgaaag atgaaagaaa gacttgttaa aataacaata
     7141 acacccaaaa ctcctgctag aaaggaataa agtttacgca tgtttttcct ccttgtcctg
     7201 tgacatataa taataaccga tcactaagag gatggagaaa aagaaaacga tggttgacaa
     7261 agcattgata tccaaggaaa ttccctgacg agcccgcgaa taaatctcaa cagataaagt
     7321 agtaaaacca tttccagtca aaaagaaagt cactgcaaaa tcatctaagg aataggtaaa
     7381 ggccataaaa taacctgcaa taatccctgg tgttaagtat ggcagcatga cttctttgag
     7441 catttggaaa taattagctc ccaaatcata agcggcgttg accatgtcct gattcatctc
     7501 tttcaagcgc ggcaatacca tcaaaaccac aataggaatc gaaaaagcaa tatgacttaa
     7561 taaaactgaa gacatgccca gctgaaactt caatgatgta aaaagaatta aaaaggaagc
     7621 cccaatcatg acatctggtg ataccatcaa gacattattg gctgatagca tggcattttg
     7681 gtacttacct ctaacatggt ggataaagat agctccaaag gtcccaataa tcgttgctag
     7741 tagagcgcta ctaaaagcaa gaacaaaggt ttgcagtaag attgtcatga gacgactatc
     7801 ctcaaacatg gtttggtaat gctcaagggt aaatcctgta aaaccattca tatccccacc
     7861 tttgttgaaa gaatagaaaa tcaaataaaa aataggaatg tagagtaaaa caaagatact
     7921 cgctaaataa agattggcaa attttttcat ttacttttct cctttgtgag ccacataata
     7981 gcaaccatgg ttaagattaa caccacacct atggttgatc ccattcccca gttttgggtg
     8041 gtcaaaaaat gttgttcaat ggctgtacca agtgtaatca cgcggtttcc accaatcaaa
     8101 cgggttaaca taaagagact caaacttggg ataaagacag actgaacacc tgccctaacc
     8161 ccatttaaag aaaggggaaa aataactttt gagaaggcct gaaattcact agctcctaga
     8221 tcgcgactgg cattgatgac attatggtca atatcatcca aagcattaaa aatcggtaac
     8281 atcataaaag ggagctcaat gtaagaggct acaaaaatga aggagaaatc cgtgaacagg
     8341 atttgctgcg agccaatccc cataaaggtt aaaaagctgt taattcctcc ttgttgacca
     8401 aagattccca taaaggcata ggcttttagc aataagttta cccaagttgg caaaataatg
     8461 agcataagcc acaactgctt gtgctttagg cgcgttaaaa agagagccgt aggatatgaa
     8521 atcaagagcg tgacgagtgt gataatacca gcgtataaaa tagaattcac actcattctc
     8581 aaataggtcc aagagctaaa aaaggtttca taattggcta aggtcacgcg cccttctatg
     8641 tcaaaaaagg acttgtaaaa caagagagtg actggtgcca caacaaagaa gagaatccat
     8701 aagaagtaag gaatcgaaaa aagactagag gttttcttca ttacgctcct cctcaatggc
     8761 attaatcaat ccctcttcag gctcatccat ttccacatat tcttcaatac gggcatcaaa
     8821 ttcctcttca gtctcattaa gacgcatgat atgaagatct tcaggggtaa aatctaatcc
     8881 gataacttct ccttcgatag ctttgcgggt agaatgaatc atccattcat tacccaattc
     8941 atcataggca ataatttcgt agtgaacccc acggaataat tgggtatcaa ccttaacttg
     9001 taatttccct tcttctggca aagtaatttg aagatcttca ggacgaataa ccacttcaac
     9061 aggctcatta gggcgcattc caccgtccac agattcaaat tctttcccgt taaaggagac
     9121 aagatagtct tcaatcatgg taccgttaat aatattagat tctccaataa aattagcaac
     9181 aaaatgatta attggctcat cgtaaatatc cactggtgtt cccgactgaa caatttcacc
     9241 ttcattcatg acaaaaatcc aatcactcat ggccaaggct tcttcttgat cgtgagtaac
     9301 aaagacaaag gtaatgccta gacgttgttg caattcacgt aattcatatt gcatctctgt
     9361 tcttaatttc aaatcaaggg ctgagagtgg ttcgtcaagt aagaccacac gcggttgatt
     9421 gataatcgca cgcgcaatgg caacacgttg acgttgacca ccagataact tctggataga
     9481 acgattttca aacccttcta attgaaccat tttcaaggtt tctttcacgc gcttagcaat
     9541 ctctttcttg tccactttct tcagcttcaa agcaaaggca acattctcaa aaacagtcat
     9601 atgagggaag agggcataat tttggaaaac ggtatgaata tcacgtttat taatcggcaa
     9661 atcattaata cgttccccat ctaaataaat gtctccgctg ctggcatcta gtaggcccgc
     9721 cataatattt aaaatagttg attttccaga gccagaagct ccaagcaggg tgtaaaattt
     9781 tccttcttca aggtcaaagt taatgttctt tagaacctgt gttccactgt cctcaaatgt
     9841 ttttgaaaca ttgttaaatg tgataattgg cttagtcaat tgtcataaat cctccacggt
     9901 actttcttta attatcaata atggttacag gttttcccca ataatccgaa cttctggttc
     9961 aagcttgaca ccagaatggt tttcaactgt ctcaatgaca taagcaatca aatcttcata
    10021 atctttagct gtgccatctg ccacattaat cataaaacca gcgtgttttt cggaaacttc
    10081 cacaccacca atccgatgcc ctttaagatt tgcttccatg attaattgac ctgcaaagtg
    10141 tcctggcggg cgcttaaaca cagatccaca agatggaaat tctaaaggtt gttttagttg
    10201 gcgaaggtga tttaaccgat tcatttcttg gctgatcgta tcataattac ccggtttaag
    10261 agcaaactta gcagaaatga caatgtcacc tgtttcttga atggcagagt gacggtaacc
    10321 aaaagccata tccctagctg aaatggtttt gatctctcca cttgaggtaa gcaccttagc
    10381 ggataagaaa atatgtgata tttccccacc ataggcaccc gcattcataa aaacagcacc
    10441 cccaatgctt ccaggaatgc cacatgcaaa ttcaaaccct gttaaactat ggaatttggc
    10501 aatcttcgtt gtttcaatca gattggcacc agcttcggct tctaaggtat aaccatttaa
    10561 gtgcactgca tttagcttat caaacatgat gacaaagcca cgaataccac catctcgcac
    10621 aatgagattg ctggcatttc ccaaaacaag ccaaggcata ttttctttgt tggcataagc
    10681 aacgatgcgt gatagctcgt agtgatttct aggaaaagcc aagaaatctg ctgggccacc
    10741 taccttagtg taagtgtaat gttttagggg ttcattctct cgaatatcaa tcccatgaag
    10801 ttcagttatc atagttatct tctttctttt atcacttctt atacacgtaa aaaaatcggc
    10861 ataaagccga tactattata tcaaatttta gaaaaaataa cgatgaattt ggcaaaactt
    10921 tatggattgg cttatagcag gcattactcc gaaaacagag tctagaactc tgtctgttga
    10981 gctgaaaaga gcgtgatatc tgattgatct aaagctgcaa gataatccct taaaaactta
    11041 tgattaggag gcaattttaa atctggctgc aattccaata aggggattaa aacaaaagca
    11101 cgctcagtca tataagggtg tggcactttc aattcctttg tgtcataaac ctcttctcca
    11161 aatagcaaga tatcaatgtc aatagttctt gatccccatt tttcatgcct cacacgacca
    11221 agagattgct caatagcttg tgtttctttt aagaaatcag ccgcggttaa ttgtgtatct
    11281 aattgacagg ccatattgag aaaatcagcc tggcctgtct tgccccaagc agtcgtttca
    11341 taaatggatg attgagcaag caaccgtgtt tgaggtaagt cagctaaagc ctcaagagct
    11401 ttttgcaagt aagctgctcg gtcccccata ttggtgccta aacttaaata aacaatggtc
    11461 atctctgtct ctccaattca ataccaactg ccttatagtg gcctgcaatc ggtgggtttt
    11521 cctttttaat ggccactttg atggcttcaa taggcggaaa ttcgttaaaa agctgttcac
    11581 aaatcgcacc tgctaaacgt tcaatcaaaa taaacttttc cccttccact aactgacgga
    11641 cactatcaaa caccatcccg taatggaccg tatctgttaa ttggtctgac aaagaagctg
    11701 cttgcaaatc gactgacaat tctaaatcaa ccagaaaaat ttgcccaagg gtctgttctt
    11761 ctttataggc tccatggtag ccataaaaac ggcaaccttc taatacgatt ttatccataa
    11821 gtcctcacat caactggctc aacacagcca caatgtcttg attagccttg acatcgtgta
    11881 cgcgtacaat ctgacagcct tttccaaggg cataagcaga caaggctgct gtcgctccgt
    11941 ctcgctcttt agctttggtg ttaccgccta acaaggcatc tacgacacgc tttctcgaaa
    12001 taccaaacaa gacaggatag cccaactgac agacgcggtc caatcctttt aataactcca
    12061 tattctgttg aacagatttg gcaaatccaa atcctggatc aatccaaata ttgttttttg
    12121 gcacgccagc atcaagagct gcttgtgctc tattgcctat aaaatcacaa acgtcttgtg
    12181 ttacctcttg ataaacttct tcgtcttggt tatgcatcaa gatgataggc gcatcgtact
    12241 cggctgctaa ggcaaacatt tgtccgtcgt acaaacctgc ccaaacatca ttgagaatat
    12301 cggcacccgc ctctaaagct gctctagctg tttcggtttt ataggtatca atgctgatta
    12361 gaatatcata gttttctttg atggccttga tcacaggaac cacccggtca atttcatcgg
    12421 tagcgcttac aaattggcaa cctggacgtg ttgattctcc accaacgtcg atgattttag
    12481 caccatcagc aatcatttgc tcaacgtgat ctaatgcttt ttgcacagta gtgtaagacc
    12541 ccccatctga aaaagaatct ggagtcacat ttaaaatccc catgatagcc gcattgccct
    12601 caatcacaaa ctttccaatt ttcataagtc ctcctaatct tttgtcatta gagaaataac
    12661 ttcttgcctc tcagcacgac tttccttgta taagcctctg gcagtggtgg taatggtttt
    12721 actacctggc tttttgatgc ctcgcatggt catgcacatg tgctctgctt ctaccataac
    12781 taaagtccct ttaggattga gggcttcaac taaagcatcc gctatttgag aggtcaaacg
    12841 ctcttggagt tgaggttgtt tactagctac ttcaactgct cgcgctaatt tactcaaacc
    12901 tgttactcga ccatcacttg gcaagtaagc gatatgagcc ttgccataaa aaggaactaa
    12961 gtggtgttca catatagaat aaaaactaat gtctttgaca atcaccacat cctcatggtg
    13021 ttctttaaag acagccgtaa attcctcttt aggatctttt cccagtccca aaaacatctc
    13081 cgcatacatt ttagcaaccc gtttaggcgt gtcaagaaga ccttcccgat ttggattttc
    13141 accaatagcc tctaaaaact gataaatggc tgcttctgct ttttccttat taatagacat
    13201 tagtctttcc cttttcatta gttttttcct tttccttttc attttctctt ttttaatggg
    13261 ttaaaagaac gcttttttca atatgttttt tccaataccg tctaatttct gaaataaaat
    13321 atagtgaccc tgtaatcacg aaaaagtcat ctgctttagc atgcttacgc agggccaaga
    13381 aatctttgaa atcagcaacc ctaccaaaac gttctgggta tttttccaat ggataggcgt
    13441 tagggtaatg aaagctagta acctgcaagt cacctatttg ctcaagagca accaacatat
    13501 ctgcaatagg cttggtgtcg atcgcaccaa acaaaatatg aagcttttta tcattgtagt
    13561 tattttttaa gacggctacc aaagcagcaa cgctttcatt gttatgagcc ccatcaatca
    13621 ttagatttgg tgctaataat tcggtacggc ctagccacaa actatttgct agaccttccc
    13681 ttatatgatc tgaagttagc ctaggatagc ggtctttcaa ggttaagcaa gtcataatag
    13741 ctaaagctgc attagacact tggtggtgtc ctggcatagc gatgtgaata tctgaaataa
    13801 ctcctaaagg actagtaaaa cgatagccag atgcgttctc agccatttga aactgctctt
    13861 gccattccca gattgaagca ccaacctgct cagcttttgt taaaaaaacc tctcgagctg
    13921 acgggttttc aacggcaaaa acaagggtct cgcccccttc taaaacacca gctttttggg
    13981 cggcaatatc agcgtaagtc tctcccaaaa tagcttggtg atctaaacca attgagggac
    14041 agaccacaac cattgcttga aaaacattgg tcgaatcata aagaccgcca aggcctgctt
    14101 caataatagc aatatctaca ggatgcatat caccaaaata gaggaacatg atcaaagtaa
    14161 tcacttcaaa ttcagttacc tctccaaaat cagtctcttg aactagacgc tctgtcaaag
    14221 gacgaatacg attagcagca ataaccaaat ctttttctga aatcattcga ccatttatgc
    14281 taatacgttc tttgaaatcc ataatgtaag gagaggtaaa ggtccccact tcataaccag
    14341 ctgtcgtaaa gatatgttgt aaatgattga ccgtggaacc ttttccgtta gttccaacga
    14401 tatgcactcc cttgacattt ttctggggat ttcctaactg tccaagaacc caaagcatac
    14461 gttttaagcc tggcttgatg ccgaaaacta agtgatcatg aatccattct agagtctctt
    14521 cataagtcat ttcatacctc acatctatct ttagtatacc atatataaaa aaaagtgaca
    14581 gcagataacc tagagtagta cccttttttt tattatcctc accaaacact caaataagtt
    14641 ctaaagtaca ctacactttt atcttcattg ctttttttac gtgataagaa taccagcccc
    14701 acatagtctt tgctacctcc taaagtgtta tctgtgacaa taattttttt actccttaat
    14761 acacgttctt ccaaaaaaca agaaaaaagg ctgacttcaa gccttctttt ctctaaaaaa
    14821 tgttacaata gaggtactta tatcaaaaaa aggagcaagt aatgaacaat agacataaac
    14881 ggcgccaaaa aagaaaagcc ttcactctca ttaaccttat actattattt gcctgcattc
    14941 ttggtttgac cctcattttc tatttatatc aagggtctaa caaattcggc ttgtcagatg
    15001 tctctcaatt tgtacctaaa ataagtcttt ttcatcacaa aaagacggca aaaaaagaaa
    15061 cgacaaaact taagaagact catttcgatt cctcaaaatc tcaaaaaaag gcccattcta
    15121 aattaacttg gaccaagcaa gaaacacctg tcaagatccc aattttaatg tatcatgcta
    15181 ttcatgtaat gtcccctgaa gagacggcta atgctaattt gattgtcaac ccagatctct
    15241 ttgatcaaca acttcaaaaa atgaaagacg agggctacta ttttttgagt cctgaagagg
    15301 tctaccgcgc tctttcaaat aatgaattgc ctgctaaaaa agttgtctgg ctaacatttg
    15361 atgacagtat gattgatttc tacaacgttg cttacccaat cttaaaaaaa tatgatgcta
    15421 aagccaccaa taatgttatt acaggactaa ccgaaatggg aagcgctgcc aatctgactc
    15481 ttaagcagat gaaagaaatg aaacaattcg gtatgtcttt ccaagatcat acagtgaatc
    15541 atcctgattt agagcaggct agtcctgatg ttcaaacaac tgaaatgaaa gattcaaagg
    15601 actatcttga taagcaatta aaccaaaaca ctattgccat tgcttatcca tctggtagat
    15661 ataatgacac taccttacaa attgcagcta gacttaacta taaattaggt gttaccacta
    15721 acgaaggaat agctagcgcg gctaatggac ttctttctct taaccggatt cgtatcctcc
    15781 caaacatgag tccggaaaat cttttacaaa caatggaacc ataacatcaa tttttttatc
    15841 attccaaatc atactcactg taaactaaaa agacagttat gaaaaaattc tttcataact
    15901 gtcttttttt gattgtttta aaattatttt attcttatct ttaacgtctt ttttcaagaa
    15961 aatctcgcca ccacagctgt aagtcagagg cttttttaag agattggcta gctttaagag
    16021 gaataggctt aggttccttt aaatacctca ctgactgatc tgttattctt ggagacgtca
    16081 aataagcaac cacttcacct ttagtaatcg gtgctaataa agaagtctct gatatcataa
    16141 attgtttagg tttgggaact tgttcaccct gttgcaaaat gatggttaca tcttcggcaa
    16201 cagatatcgg tagttctttt acttggccat cttgaatagg gagcgaccgc tccgagacaa
    16261 gacttccttt tttaagaatc ttacgacgac aataagttct agccacatag tccaacaagc
    16321 gatttgcttg ctcaaaccgc gtgttttggt ttttatcaga tccatcagca tttagaataa
    16381 cggtaatcag cctcatacca ttttcaatag aagttaccac aaggcaatga cctgccaaat
    16441 ctgtcgttcc tgtctttagc ccatccactc ctgctctacc cttagccata cctggtaaga
    16501 gttgattaaa acttttaata gaattaccag caaaatcaac ttctgtttgt ttagtgatct
    16561 ctaaaatctc aggaaaatct tccagtaaat gcatcgtcac aatggcaaca tcctgagcac
    16621 tcaacatatt ctcttcttcc aacgcagaac caggataacg atggtccttt agcacctcat
    16681 tcggcagtcc tgaagcattg aggattttac cagaagtaat cccccaatga gatagctgtt
    16741 ctctcatttg atttacaaaa tgaagctctg agcccgccac tttttcggct aacgcaatag
    16801 cagcgctatt tgagcttgct accaaagtag ttgtcaacag gtcttgaact gaataagttt
    16861 ttttgtcaaa aggtacatta cttaaagacc tatcttttgt taactcgaag gcataatctg
    16921 agagattaac ttgatctgat aattgcagct ggcctgattt aaccttatct aaaaccagat
    16981 aagccgtcac caatttggtc aaagaggcaa tagcatctgg cgttttagcg tttttctcat
    17041 acagaactct cccagagtct gcctctacga caatcgcatg ttctgctccc acttgaaaat
    17101 cagctgcgag aactgtttta ccaaaccctg aacaagttaa taccataaaa aaaaggataa
    17161 cccacctttt tatcattata tctttcatag ttactattat aacaaaaatt ctcagaaatt
    17221 tggaaggaag tatagtggca cacaccttta gtagcttaaa caagctcata aagcaagtac
    17281 cctgtaacaa taacacatcc tgttatatgg gcgatataat aagcttcgtt atatcaatta
    17341 gttatttggc aggaattttg gtataaaatg gaatctaatc ctgaacttat tacattttgg
    17401 gttatttctt cagatactgt tttatctaat gcattaaatc agtgactata tgtattcaaa
    17461 gttgtagact tatcagcatg tcccatacac tttgcaacgt acagaatgtc ttttttcaaa
    17521 acattaataa gataggaagc ataactatgt cgcaatcctt ttccagttat tacgggaact
    17581 ccaatacttt gagctttgtg cttaataact cgacaaatcg ttgatttaca aaatggttca
    17641 ccaaaccgtg aaataatgaa atctgtgtca gtattgacta cttgatttct tctccaattt
    17701 tccaatacta ctattgtcac atcatctaac tcaataagac gttctcctgc tggcgttttt
    17761 gtttggtctt tacgatacca atttccattt tcatcctttt ccaaggttgt atgaactttc
    17821 aagaattttt gttcgaaatc gatattttcc catcataatg ataaaccttc acttacacga
    17881 acacctgtca tataatatag ccaaatagtt gtaaatcttt gtagctcttc ataatcttgc
    17941 aaatcaaacg attttataaa attctgaaac tcaatataag tccaaaatgg agtgtcggga
    18001 tgtttccctt taggattatc caaagcctta catggcactt ttgaaatata gtctaacctt
    18061 tcagcatacc ccatgcaagc tttgaatcgc gaccataaat tctttgcata attttcaata
    18121 atatgtaaac taaaagattc acaatctcaa gctgttattc cctttaaaag tttagaatca
    18181 aaatactgaa taaataactt atgatgtggt aaggctattt cataagttac agcctgaacc
    18241 ttttgctta
//
LOCUS       DAUNLR010000034        17949 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUNLR010000034 DAUNLR010000000
VERSION     DAUNLR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17949
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.034"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            410..799
                     /locus_tag="VLL59_001199"
     CDS             410..799
                     /locus_tag="VLL59_001199"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HER6509323.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            893..1945
                     /locus_tag="VLL59_001200"
     CDS             893..1945
                     /locus_tag="VLL59_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HER6509324.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2084..3616
                     /locus_tag="VLL59_001201"
     CDS             2084..3616
                     /locus_tag="VLL59_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509325.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGVPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNKEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINEYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3609..4673
                     /locus_tag="VLL59_001202"
     CDS             3609..4673
                     /locus_tag="VLL59_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509326.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4675..5631
                     /locus_tag="VLL59_001203"
     CDS             4675..5631
                     /locus_tag="VLL59_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509327.1"
                     /translation="MSLVTIFALLMSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5844..7562)
                     /locus_tag="VLL59_001204"
     CDS             complement(5844..7562)
                     /locus_tag="VLL59_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HER6509328.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKSKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSSGLIQVVGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7738..8307)
                     /locus_tag="VLL59_001205"
     CDS             complement(7738..8307)
                     /locus_tag="VLL59_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HER6509329.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8365..8910)
                     /gene="coaC"
                     /locus_tag="VLL59_001206"
     CDS             complement(8365..8910)
                     /gene="coaC"
                     /locus_tag="VLL59_001206"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HER6509330.1"
                     /translation="MTKHITLAVSGSISAYKSADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(8903..9595)
                     /gene="coaB"
                     /locus_tag="VLL59_001207"
     CDS             complement(8903..9595)
                     /gene="coaB"
                     /locus_tag="VLL59_001207"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HER6509331.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKRLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9776..10627
                     /locus_tag="VLL59_001208"
     CDS             9776..10627
                     /locus_tag="VLL59_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HER6509332.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKKEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKAFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10624..11823
                     /locus_tag="VLL59_001209"
     CDS             10624..11823
                     /locus_tag="VLL59_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HER6509333.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11820..12818
                     /locus_tag="VLL59_001210"
     CDS             11820..12818
                     /locus_tag="VLL59_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HER6509334.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12860..13192
                     /locus_tag="VLL59_001211"
     CDS             12860..13192
                     /locus_tag="VLL59_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HER6509335.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13185..13997
                     /locus_tag="VLL59_001212"
     CDS             13185..13997
                     /locus_tag="VLL59_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HER6509336.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAHIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            13990..14871
                     /locus_tag="VLL59_001213"
     CDS             13990..14871
                     /locus_tag="VLL59_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HER6509337.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            14918..15937
                     /locus_tag="VLL59_001214"
     CDS             14918..15937
                     /locus_tag="VLL59_001214"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HER6509338.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATGVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     YLIFS"
     gene            16065..17735
                     /locus_tag="VLL59_001215"
     CDS             16065..17735
                     /locus_tag="VLL59_001215"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HER6509339.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVHDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
BASE COUNT         5476 a         3095 c         3762 g         5616 t
ORIGIN      
        1 aaccatacgc tactaaagat aggtagcgtt cgatcacagg ttgatcaagt gattgaaaag
       61 tcaatattta taattttaca aatatttgta tcaatccatg ttgaatagtc tatgcttcta
      121 aggtgtcgac gttaatgtac tgacgggacc gttatagtct ttctttttgg agaaacgtcg
      181 gatgccagtg aactagttga agttaaagat gttaattcaa acagtgctga agagattgat
      241 atcgttttga acggtcgttt acttcaaagc aaagaaatta ccagtctatc gaagatgata
      301 taagtgctaa agttagatca cgttaattat ctatcaagtc gggtgcatat ttcgttaaag
      361 tatctacagg ggtttcaata gatgtagcta ttatgaaagg tgatgttaaa tggggactac
      421 tgatttagtt agttgtgctg tacaagctag tgagtatgct tatgtccctt actctcattt
      481 tccagtagga gcagctttaa aaacaaaaga tggaacgatc tatactggct gtaatattga
      541 aaatgttagt tttggtctga caaattgtgg agagcgaaca gctatattta aagccatatc
      601 tgatggtcat aaagaattgg ttgaaattgc tatttatgga gaaactatgc aacctgtatc
      661 tccttgtggg gcttgtcgtc aggtaatggc agaatttttt gatccttctt ctttagtcac
      721 tttaattgct aaaaatggtc aaactgttga aatgactgtt ggagatttac tcccctattc
      781 ttttacagat ttaatataat ctgctttaat ttctgttatc tagccgtctt ggctttatat
      841 ttactttcag caacttattt gctagaaatc ttttttagga gggttcatat tcatgaacaa
      901 gaaatttatt ggtcttggtt tagcgtcagt ggctgtgctg agtttagctg cttgtggtaa
      961 tcgtggtgct tctaaaggtg gggcatcagg aaaaactgat ttaaaagttg caatggttac
     1021 cgatactggt ggtgtagatg acaaatcatt caaccaatca gcatgggaag gcctgcaatc
     1081 ttggggtaaa gaaatgggcc ttcaaaaagg aacaggtttc gattattttc aatctacaag
     1141 tgaatctgag tatgcaacta atctcgatac agcagtttca ggagggtatc aactgattta
     1201 tggtatcggc tttgcattga aagatgctat tgctaaagca gctggagata atgaaggagt
     1261 taagtttgtt attatcgatg atattatcga aggaaaagat aatgtagcca gtgttacctt
     1321 tgccgaccat gaagctgctt atcttgcagg aattgcagct gcaaaaacaa caaaaacaaa
     1381 aacagttggt ttcgtgggcg gtatggaagg aactgtcata actcgatttg aaaaaggttt
     1441 tgaagcagga gttaagtctg ttgacgatac aatccaagtt aaagttgatt atgctggatc
     1501 atttggtgac gctgcaaaag gaaaaacaat cgcagcagct cagtatgcag caggtgctga
     1561 tgttatttac caggcagcag gaggcactgg agcaggtgta tttaatgaag caaaagctat
     1621 taatgaaaaa cgtagtgaag ctgataaagt ttgggttatt ggtgttgacc gtgatcaaaa
     1681 agacgaagga aaatacactt ctaaagatgg caaagaagca aactttgtac ttgcatcatc
     1741 aatcaaagaa gttggtaaag ctgttcagtt aatcaacaaa caagtagcag ataaaaaatt
     1801 ccctggagga aaaacaactg tctatggttt aaaagatggc ggtgttgaaa tcgcaactac
     1861 aaatgtttca aaagaagctg ttaaagctat taaagaagcg aaagcaaaaa ttaaatctgg
     1921 tgacattaaa gttcctgaaa aatagtgttt aagaacaaga agcgcgacct ttgtcggtcg
     1981 ctctttttaa actgagataa tttttatctc agtaaagttt gtgataggtg atagatcata
     2041 ggctttactg aaataaaaga ttgcattgaa aggaaatgat cctatgacac agcatgtcat
     2101 tgaaatgaga gaaatcacga aaaaatttgg tgattttgtt gcaaatgacc acattaactt
     2161 aaatgtcaga aaaggtgaga ttcatgcctt attgggtgaa aatggggcag gtaaatcaac
     2221 tttgatgaat atgctagctg gtctcttaga gcctactagt ggagaaattg tcattaatga
     2281 caagccagtt caaattgatt cgccatctaa atcagctaag cttggtatcg gaatggtaca
     2341 tcaacatttc atgttagtag aagccttcac ggttgctgag aatattattt taggaaatga
     2401 agtagtaaaa aatgggtgct tagatcttaa ccaagcatcg aaagatatta aggtactatc
     2461 cgaaaaatat ggccttgcaa tcaatccatc agctaaagtt tctgatattt cagtaggagc
     2521 acaacaacgt gttgagattt tgaaaacctt gtatcgtggt gcagatattc ttatctttga
     2581 tgagccaact gccgttttaa cacctgcaga aattaaagaa ttgatgacta tcatgaagaa
     2641 tcttgtgaaa gaaggaaaat caattatttt aattacccat aaactggacg agattcgtgc
     2701 tgtcgccgac cgtgtcacag ttattcgtcg tggtaagagt atcgaaacag ttgatgtggc
     2761 aggagcaact tcacaagatt tagctgagat gatggtggga cgctcggttt cctttacaac
     2821 tagcaaaaaa gctgctgaac caaaagatgt ggtcttatcc atcaaaaatc ttgaagtaga
     2881 tgaaaataga ggggttccag cagttaaggg gctatctcta gatgtccgag ctggtgaaat
     2941 tgtagggatt gctggaattg acggaaatgg tcaatctgag ttaattcaag ctattacagg
     3001 tttacgtaaa gtcaaatctg gaagtattat gattaaaaac aaagaagtca ctcatttgtc
     3061 ttcacgcaaa attactgagt tatcagtggg tcacgtgcca gaagatcgtc atcgagatgg
     3121 tttgatacta gatctttctt tagctgaaaa tacagcctta caaacctatt acaaacaacc
     3181 tctaagtcaa aatggaatct taaattatac taaaattaat gaatatgctc gtcaattaat
     3241 gaaagaattt gatgttcgcg gagccaatga gctagtacca gctagaggat tttctggtgg
     3301 taaccaacaa aaggccatta ttgctcgtga agtggaccgt gatccagatt tacttattgt
     3361 tagccaacca acacgtggtc ttgacgtagg agctattgaa tatatccata agcgtttgat
     3421 taaagaacgt gataaaggta aagctgtcct cgttgttagt tttgaacttg atgaaatatt
     3481 gaatttatct gatcgaattg ctgttattca tgatggtaaa attcaaggta tcgtattgcc
     3541 agaaaatacc aataaacaag aattgggtat tttaatggca ggtggttcaa ttcataagga
     3601 ggaaggtcat gtctaaaaat gcgcaaaaaa ttgctgtacc attgatttct gtcttgctag
     3661 gatttttact tggcgctatt attatggtta tctttggtta tgatcctatc tgggggtatg
     3721 aaggtttatt ccaaattgcc tttggtagtg ttaaaaatat tggagaaata ttccgttcaa
     3781 tggggccatt gattttaata gcgcttggct ttactgttgc tagccgtgca ggcttcttta
     3841 acgttggttt gtctggacag gctttagctg gatggatttc agcaggttgg tttgcactct
     3901 taaatccaga tatgcctcgt ccattattga ttcttatgac agctcttatc ggaatgattg
     3961 ctggtggtat tgctggagct attccaggga tacttcgtgc ttatcttggt acaagtgaag
     4021 ttatcgttac gattatgatg aactacatca ttttatatgt cggaaatgct attgttcaac
     4081 gtggttatcc tgagagtgtc aaacaaagta ttgattcaac tattcaagtt agtgataatg
     4141 ctagttatca aacgcattgg ttatcagccc taactaataa ctctcgtatt aatattggta
     4201 ttttctttgc cattattgcc attgccctaa tctggttctt gcttaacaaa actactttag
     4261 gttttgagat tcgttcagtt ggtctcaacc cacatgcttc agaatacgca gggatgtcat
     4321 caaaacgtac tatcatttta tcaatgatta tctctggagc tcttgcaggt cttggaggag
     4381 tagttgaagg tctaggaacc tttgaaaatg tttttgtaca aggatcttct ttagcagttg
     4441 gttttgacgg tatggcagtt agcttattag cagcaaattc accgcttgga atatttttct
     4501 catcattcct atttggtgtc ttaaatattg gtgctccagg aatgaatatt gcaggcattc
     4561 caccagaact tgttaaagta gtaactgcat caatcatttt ctttgttggt tcacattacc
     4621 tcattgaacg ttacattatt cgccctaaaa aattagtgaa aggtggtaaa taagatgagt
     4681 ttagtaacaa tttttgcctt attgatgtca tctatgctta tttatgcaac accactcatt
     4741 ttcacaagta ttggaggaac tttctcagag cgctcaggcg ttgttaatgt tggtttagaa
     4801 ggtatcatgg tcatgggagc gttctctggg attgttttca acttagagtt tgctgaaaca
     4861 tttggaaaag caacgccttg gatagccgtt ttagtcggtg gtattgttgg tttgattttt
     4921 tctttgattc acgctgtagc aaccatcaac tttcgagctg accacattgt cagtggtaca
     4981 gtgttgaact tgttagcacc ttcttttgct gtcttcttgg ttaaagctat gtacggtaag
     5041 ggacaaacag acaacattca acaatctttt gggaagtttg atttcccagg tttatcacaa
     5101 attcctgtga ttggtgatat tttctttaaa aatactagcc ttattggtta cttcgccatt
     5161 gctttttcgt tctttgcttg gtttttgctt tataaaacca ggtttggtct gcgtttacga
     5221 tcagttgggg aacaccctca ggcagctgac acacttggta ttaacgtcta tttgatgaaa
     5281 tactatggtg tgatgatctc aggttttctt ggtggaatag gtggagctgt ttatgctcag
     5341 tcaatctccg ttaactttgc tgtaacaact atcctaggtc ctggatttat tgctttggca
     5401 gctatgatct ttggtaaatg gaatccagtt ggcgccatgc tatctagtct tttctttggc
     5461 ttatcgcaaa gtttagccgt tattggtgct caattaccat tactagaaaa gattccaacg
     5521 gtttacttac agattgcacc ttatatggta acgattatta ttttagctgc tttctttggt
     5581 caagcagttg caccaaaagc tgatggaatc aactatatta aatctaaata acgttatatt
     5641 agtaagcctc ttagtgaggt ttaacagcac tcctaaagca agatagttag gtctagcttt
     5701 aagggtgctt ttttgggact taccgcaagt ttggattgcc agtcaccatc acaatagaag
     5761 caagaataga ctaaaaagaa ctaagtcagc ggcttagttc tttttgcttg tcttttgttt
     5821 ttactgatag ctcttaagtt gttttagcca acaaaggtat tgatttctgt ttcaatgtta
     5881 gcaatttttt cttgagcgat gtcaagagta tcacctattg tggcaatata gaacttgatt
     5941 tttggttcag ttcctgaagg gcgaactgca atccatgaat catcagctaa cgtgtacttc
     6001 aaaacattac ttggaggagt tgttaagtta gatattgttc catcattttt agtagcggtt
     6061 tgtttttgga aatcttctaa taatacaata tcagtattgt taaattgttt tggaccattt
     6121 tcacggaatt tgtccataat cttcttaatt tcagcagctc catccacacc tgaaagtgtt
     6181 actgaaatcg ttttttcagc aaaatagcca tattctttgt aaatttcatc aataccatct
     6241 gcaagtgtta aaccacgcga acggtaataa gctgcgatct cagcaaccaa aagaactgct
     6301 tgaatagcgt ctttatcacg gacaaatggt ttaataagat atccgaagct ttcttcaaaa
     6361 ccaaacatat aggtgtggtt atgtttttct tcaaactctt gaattttctc agcgatgaat
     6421 ttgaatccag ttaaaacgtt aaacattgta gcgccataac tttcggcaat ttttgttact
     6481 aattctgttg atacgattga tttagcgaga gcagcatttt ctggaagtgt tcctgctgtt
     6541 ttatgagctt ccaggatgta tttcgcaata atcgctccaa tttgatttcc agaaagattt
     6601 ttataagaac catctggttg gcgaatttca acgcctaggc ggtctgcatc aggatcggta
     6661 gctactaaga catctgcatc aacttctcgt ccgagttctt cagcaagagc aaaggcagct
     6721 tggctttcag ggttaggcga tttaacagta gaaaagtctg gatctgcctt agcttgtgat
     6781 tctactacaa caacagattc aaaaccggct tgagcaaggg cacggcgtgt caacatctca
     6841 ccagttccgt ggagaggagt atagacaatt ttcatgtctt ttccaaagtt attgattaaa
     6901 tcttgattga tattaacatc tttaacctct ctaagatatt ccatatcaac atcttcaccg
     6961 acaacttgaa taagacctga tgatttgctt tcatctaaat cagcaagttc aactgcaaac
     7021 ggattttcaa tagcacggat aaagtctgtt agtgcatcag catcagctgg tggtagttga
     7081 cctccgtctt gtccatagac tttataacca ttgaaaggtg ctggattgtg gcttgcagta
     7141 accataatac cagcataggc atttaaatgg cgaacagcaa aagagagttc tggtgttgga
     7201 cgaagagctt caaatacgta agatttaatt ccatgctgtg ccaagacctg tgcagactca
     7261 aaagcaaatt ctggagagaa gtggcgcgaa tcataagcga tggctacacc acgtttttta
     7321 gcttcctctc ccttagtttc gattaatttt gctaatcctt cggttgcttg acggacaaca
     7381 taaatattaa tacgatttgt accagcacca atataaccac gcataccagc agtaccaaat
     7441 tctaagtttg tgtaaaaagc atcttctttt gatttttcat ccattgatag taattcttga
     7501 cgaagatagt caggaagctg ctcaaaatct aaccattttt gaaaattttc tgtgtaagtc
     7561 attgaaatac tccttcaata tttataaacg ctttcattat atcattttga aggaaaaaaa
     7621 acactaatta tttgcagctg tttacaaaac tttttccata ttttcaagta gctaatgtaa
     7681 gaaagttaaa ataaccaagt ttttaaaaga gaaaaactcg gttattgtga aagctaatta
     7741 cctttttagt cttgatagtg ttggaataag tacaaaggta ataatagctg agatgatcat
     7801 ctcaacaata gcgtttgatg agatgatggc tgttagtagt gctttaatat ttccatcaaa
     7861 aactgtcgcg aaaaaaataa atatcccaga taatacaaat atagtatttg ttagagaacc
     7921 aatgataccg gagactatta aaccaaactg attaggaatc aatttatagc aataataagg
     7981 ggtaatacca atcaaaatac gtgggataat agcaattatt aaagaagcga aagttccatg
     8041 atcgacaaaa ggtgaaaaga gataatttgt aggcagtaga atgatggtat ttgtaatgac
     8101 acttataatc cccattaatc ctcctaaaat agcacctatc cttgggccat ataagacaga
     8161 agcaataata actgggatat ggacaagcgt tggtttgatt ggaataggcc aaatattaaa
     8221 gacaagactg ctcacaaaat gaatgactaa catgatggca aaaaagatag caatacgaga
     8281 aatatctgct gatttacggt gattcatttt actctccaaa aaatataata cttaattcta
     8341 aaaaggtgat cagaaaaaca actgttaaag tttccaaatc gtatcaatag tagctaagat
     8401 aacatcaata tcagccaaag caccaggtcc tttatctcca caggctaata agctagattt
     8461 tggaggaatt tctgtaaacc ctattgtcga taagcgttta atattttctt gggtaatagg
     8521 gttttgatac attttggtat tcatggctgg ggctattaat tttggtgtgg tagctggtag
     8581 ggcaagagca acacttgtta caatattatc agcgaatcca tatgctagat gagcaatagt
     8641 attagcagag gcaggtgcaa caataaataa atctgtgcgt tttgctaatt cgatatggtt
     8701 gataactttt gggtcatgct catccataac atctaaatga atagcatttt ttgataacac
     8761 ttgcagggtt aatggtgtaa taaattgtgt agcagcctga gtcattatga tgtgaacatc
     8821 atagccaatt ttagttaatt gactcgtaag atctgctgat ttataggcag atatactacc
     8881 agaaacagct aaggtaatat gtttagtcat gtttggtcat cctttcatat aataagtcag
     8941 caattgcctc tttggtatct gcagatgcaa cttcgttatt ggatatcaaa agagccttgt
     9001 gcatacctgt ttggatatca actaaatcat tggcgagaat ataatcagca tggtttttag
     9061 ctagacttgc tctggctact ttaattaact cttcttgagg cacattaact agaagtttaa
     9121 agccgactag tttaatatta ggattccact gtttaacata agagataact ttgggtgttt
     9181 ttttcaaaaa aagaacctga taatcagatg cagatgagat tttcggctca ctgttatgtt
     9241 cacatagaaa acaattaagg ttatcagctt gagagacttg ttccaaatca gtcatgtaga
     9301 ctggagtata gtcagaaaca gccatactat gaattagaat gtcatggtga ggaacctgat
     9361 ctttgagtgc agccattaag tcgttaactg tttccacttc aataatcctt aggcgcttat
     9421 ttggcagggg tttagtggct gttttagtag tgactagggt aacgtcatga tgatattgta
     9481 aaaatcgctc tgtgattaat tttccaagtt gcccagttga gtgattagtg atacctcgta
     9541 ctgcatctat aggttcagtt gttccacctg atgttattat taatttcata gtcatatttt
     9601 atcaaaaaag gagctgatag taaacggaag ataatgacgc cagacattgt cttgcgtttg
     9661 tattaatatg gaatagtaat agatttctag taattaaaac gaagttctgg aaagcaagac
     9721 actatagtag ctaaaatcta aattttaagg taaaatagag caagcggttt caagtgtgaa
     9781 aggaagaatt gtgataacta ttagagattt agcgtcactg ccgatttttg tttacggtga
     9841 tggaaataaa aaagttccag gagctttgag tccttttgtg tggacagagg tgtttttaaa
     9901 aactatcaat caagaaccta atcaactgat cttacatatt tggccgatga caagaacagt
     9961 tatattagga atgttagata gacagcttcc ctactttgag cttgctaaaa aagagattgg
    10021 caataatggt tatgttcctg ttactcgtaa tattggcggt ttggctgttg tcgctgatga
    10081 tgggattttg aatttttcgc ttgttattcc agaccatttt tcggaatcta tcagtattag
    10141 taatgcttat ttaataatgg ttgatgtcat tagagagagt ttttcggatt attatcagcg
    10201 tattgaatat cacgaaatta aaaattctta ttgccctggt aattttgatc ttagtattgc
    10261 aggccgcaag tttgcaggta tcgcccagcg tcgtatcaaa aagggaattg ttgtgtctat
    10321 ttacttgagc gtttgtgggg atcaagcagc gcgtggtcaa ctcatcaagg ctttttatga
    10381 ggctggaaca caaggagaag ttaccaaggt taattaccct caaattgatc cagaatgcat
    10441 ggcaactctt tcagaactcc ttgagacgcc ttttacagtg gcagaagtcc ttgaacgtct
    10501 tcgattgacc ttgcgacagc ttggcttttc cctcacggaa aaaagtccag atcaagcctt
    10561 actgactaat tttgatgctg tctatgaacg gatgcagcta gaagtcgtca gaaaggaagg
    10621 caaatgaaag aaagatttag tcctttattt gagcctttga ctttgccaaa tgggagtcaa
    10681 ttggataatc gctttgtttt gtctcctatg gtgaccaact catccacaaa agacggttat
    10741 gtcacccaag atgatgtatc ctatgctttg agacgagcag cttctgcccc tctacaaatt
    10801 acaggagcgg cctatgtgga tccttatggt caattgtttg aatatggttt tagtgttaca
    10861 aaagatgccg atatttctgg cttgaaagag ctagctcaag cgatgaaggc aaagggagct
    10921 aaagctgtct tacaactgac ccacgctggc cggtttgcta gccatgcctt gactaaatat
    10981 ggctttgtct atgggcctag ttacatgcag ttgagatctc cccaacctca tgaagtcaaa
    11041 cctttaacag gtcagcaaat agaggaattg attgcagctt acgctcaggc cactcggcgg
    11101 gcaattcaag caggctttga tggcgtggaa gtatcttcgg cgcagcgctt attgattcaa
    11161 acgttctttt cgactttttc gaacaagagg acagatagtt atggttgtca aacacttttt
    11221 aatcgctcta agttaacttt agctgttttg caagctgttc aacaggtgat taaacaagaa
    11281 gctcctgatg ggtttatttt tggatttcgt gctacaccag aagaaactag gggaaatgat
    11341 attggttata gtattgacga gtttttgcag ttgatggatt gggtacttaa tgttgcaaaa
    11401 cttgattatt tagcgatagc aagttggggc cgtcatgtat ttcgaaatac tgttcgttct
    11461 cctggccctt attatggaag gcgagttaat caggtagtta gagattattt aagaaataag
    11521 ctacctgtta tggctacagg gggaatgaac acacctgaca aagctattga agcactagct
    11581 catgctgatt ttattggagt atctacacct tttgtcgtgg atccagaatt tgctcataaa
    11641 atcaaagaag ggtgtgaaga gagtattcat ttaaggattc gacctgctga tttgaaaagt
    11701 ttagcgattc ctcaggcttc tttcaaagat atcgtacctt tgatggacta cggggaatca
    11761 ttgcctaaag aatcaagaac tttatttcgt agtcttactc acaattataa ggagattaaa
    11821 tgaaagtcag tattcttgat tatggggtga ttgataaaga aaaaacaccc caagaagctt
    11881 tattagaaac gcgctgctta gcacaagtag ccgacaaact tggttttcat cgtttttggg
    11941 tagcagagca tcataatatt tatgcctttg caataagcag tccagagctg ttgatgatgc
    12001 atttagcaga tcataccaaa cagattcgga taggttcagg aggtattatg cctctacatt
    12061 atagtagctt taagattgca gaatggataa tgactttaga ggccttgcac cctaatcgga
    12121 ttgatttagg tattggcaac tctttaggaa ctacgttagt tcaaagagct ctatcaagta
    12181 tccattgcaa agacagctat agtcaggttg tcacagaatt ataccagtat cttaatcctg
    12241 atcatttgtc accactaccg atttttgtta accctagggg taatacttac cctcagattt
    12301 ggacgctaag caatagtttg gagacagcag aactggctgg tcaattaggt ttaggctata
    12361 cctttggtat tttcccctat ataccaaaag atcctataac agaagctaaa agagtatcgg
    12421 cacattatag aaaggctttt aggccttcaa agctattaaa aatccccaag ttaatattag
    12481 cagtttttat tgtcctttct gataccgacg aggaagcaga agctttggct aaaccgttgg
    12541 acatttggat gcttggtcag caagatttta atgaatttaa gacctaccct gatgttgagg
    12601 aggctagaaa ctatcactta acagagaaac aaagagaagc cattgcagca aatcgtagtc
    12661 gcatggttat tggatcacct cacacagtca agaaacaatt ggataggctg atagaagctt
    12721 gtcaagctga cgaattatta gccatcccct tagttcctga atttgccaat agacaacgaa
    12781 ccttagagct gctagcagac ttatacgtga ccatttaacc ttaccaaaaa caattcccta
    12841 aactgaaagg aaagaaacaa tgaaaaaaat tgcaaattac ttattaattg agaaaacaga
    12901 tgaccgctat accattagca tgacaccaga attacaagac gatattggta ctattggtta
    12961 cgctgaattt acggataacg accaccttgc cgttgatgac attatcttaa atctagaggc
    13021 ttctaagacc gtcatgtctg tcttgtcacc attggctggg gcagttgttg agcgcaatga
    13081 ggcagccaca ctaacaccaa cccttttgaa ttcagaaaaa gctgaggaaa attggattgt
    13141 tgtgctaaca gatgttgatc aagcagcttt tgatgcccta gaagatgcct agttcatttg
    13201 atttattagg ggaaatgatt ggtctgttgc aaacagagca gcttactagt tcttgggcct
    13261 gtcccttgcc taatgcttta acaaagcgac aagacttgtg gcgggcgctc attaaccagc
    13321 gccctgcttt gcccttatca aaagattact tgaatctgga agatgcttat ctagatgatt
    13381 ggcgtgcttc ttttgttcct gtatcagtca aggattgcca aaaaactaat tataccagtc
    13441 tttttcttta ccatggggat attaggtacc ttgctgtgga tgctattgtc aacgctgcta
    13501 atagtgagtt attgggatgt tttattccta accatggctg tattgataat gcgattcata
    13561 cgtttgccgg aagtcgttta cgcttagctt gtcaggcaat catgactgaa caaggccgta
    13621 aggaagccat tggccaagca aagcttacca gtgcttatca tctaccagcc tcttatatta
    13681 ttcataccgt agggccaaga attaccaaag gacaccacgt ttctccgatt cgagctgatt
    13741 tgttagcacg ttgttatcgt tctagtcttg atttggcggt taaagcagga ttgactagcc
    13801 tagctttttg ctctatttca acaggagaat ttggctttcc taaaaaagaa gccgctcata
    13861 ttgctattaa gacagtttta aaatggcaag cagaacatcc agaatctaag accttaacta
    13921 tcatttttaa tacctttaca tcagaagaca aggccttata cgacacttat ttgcaaaagg
    13981 agaataactg tgagtaattg gacaacctat cctcagaaaa acctcaccca ggcagaacaa
    14041 ctggcccaat taatcaaaga agcagatgca cttgtagttg gtattggagc tggcatgtct
    14101 gcagctgatg gttttactta tatcgggccg cgttttgaga cggcattccc agattttatt
    14161 gctaagtatc agtttttgga catgctgcaa gctagccttt ttgattttga agattggcaa
    14221 gaatattggg cttttcaaag tcgctttgtc gctttgaatt atcttgatca gcccgtaggc
    14281 cagtcttatc ttgatttaaa agagattttg gaaaccaaag actatcatat tattactact
    14341 aatgctgata atgctttttg ggtggctggt tatgatcctc ataacatttt tcacattcaa
    14401 ggggaatatg gtttgtggca atgtagccag cactgccatc agcaaactta taaggacgat
    14461 acggtcatcc gtcaaatgat cgcagagcaa aaaaacatga aagtcccagg tcaactgatt
    14521 cctcattgcc ctgaatgtga ggcgcctttt gaaatcaata agcgtaatga agaaaaagga
    14581 atggttgaag atgctgactt tcatgcccaa aaagcacgtt atgaggcttt tttatcagaa
    14641 cataaagagg gtaaagtgct ttatctagaa attggtgtgg gacatacgac gcctcagttt
    14701 atcaaacacc ccttttggaa acgtgtctca gaaaacccta atgccttatt cgttaccttg
    14761 aatcacaaac attaccgcat ccctctgtca ataaggcgac aaagcctaga actgacagaa
    14821 cacattgccc aattgattag cgccacaaaa accatttacc aaaaatcgta accaaagcca
    14881 atagacggtt aattaagaga tagagatgga gactaacatg taccttattg aaccgattcg
    14941 taacggtaaa cgtatcaccg atggagctgt tgctctagcc atgcaagttt atgttcaaga
    15001 aaatctattt ttagatgatg atattttatt tccctactat tgtgatccca aagttgaaat
    15061 tggaaaattc cagaatgcag ttgtagaaac taatcaagag tatttaaaag agcatcatat
    15121 ccctgttgtt cgcagagata ctggcggtgg tgccgtttat gtagattctg gtgctgttaa
    15181 tatttgctac ttgattaatg ataatggtat ttttggtgat tttaaaagaa cctatcagcc
    15241 cgctattgaa gcccttcatc atttgggagc aacaggggtt gaaatgtctg gacggaatga
    15301 cttggttatt gatgggaaaa aggtatctgg cgctgcgatg actattgcta atggccgtgt
    15361 ttatggggga tattcccttt tgctagatgt ggactttgaa gccatggaaa aagcattaaa
    15421 acctaatcgc aaaaaaattg aatcaaaagg catcaggtca gttcgtagtc gcgttggaaa
    15481 catcagagaa catttagcac cacaatacca aggtattacg attgaagagt tcaaagattt
    15541 aatggtttgc caattgttac agattgagac gattagccaa gctaagcgtt atgatttaac
    15601 ggaaaaagac tggcaacaaa ttgatgcttt aacagagcgt aaatatcaca attgggaatg
    15661 gaattatggc aacgcgcctc aataccgtta ccatagagat ggccgtttta ccggtggaac
    15721 agtagatatt catttagata ttaaaaaagg ctatattgca gcttgtcgca tttacggaga
    15781 tttttttggc aaggcagaca ttgcagaact tgaaggtcac ttgataggaa cacgaatgga
    15841 aaaagaggat gtcttagcta ccctcaatgc aattgattta gccccttatt taggtgcgat
    15901 tacagcagaa gaattaggat atttgatatt ttcttgataa aaaagatacc tcagaccggt
    15961 aaagtgcgat taaaaacgaa caataattgt tttaattcaa ataaatgtat gtatgatatg
    16021 aattgtgata taatgacgtc attacgtaaa attgaggagt catcatgaaa tcagatatcg
    16081 aaattgccca aagtgtcgcc ttacaaccaa tcactgacat tgttaaaaag gttggaatag
    16141 acggcgatga cattgagctt tatggcaaat ataaggctaa attgtctttt gagaaaatga
    16201 aagctgtcga agctaatgag cctggaaaat taatcttggt aactgctatt aaccctactc
    16261 cagcaggaga aggaaaatca accatgtcta ttggactggc agatgcctta aatcaaatgg
    16321 gaaaaaaaac catgcttgcc ttacgtgaac cctcccttgg tcctgttatg gggattaaag
    16381 gcggggcagc aggtggtggt tatgcccaag tattgcctat ggaagacatt aatcttcact
    16441 ttactggtga catgcatgcc attacaaccg ctaataatgc attatctgct ttgattgaca
    16501 atcatttgca gcaaggaaac gatttaggaa ttgatcctcg ccgcattatt tggaagcgcg
    16561 tgttggacct taatgatcgc gctcttcgtc aggtaattgt tggcttaggt agtccagtga
    16621 atggtgtgcc acgcgaagat gggtttgata tcacagtagc ttctgaaatc atggcaattt
    16681 tatgtttggc aactgactta aaagatctaa agaaacgtct tgctgatatc gtcgtggctt
    16741 atacctatga tcgtaagcct gtctatgtgc atgacttgaa ggttgaagga gcattgacat
    16801 taattctaaa agatgctatc aagccaaatt tggtgcagac tatttatgga acaccagctc
    16861 ttattcatgg ggggccattt gctaatattg ctcatggttg taattctgtc cttgctacct
    16921 caacagcttt gcgattagca gattacactg ttaccgaagc aggattcggg gccgacctag
    16981 gagctgaaaa attcctaaat atcaaagtac ctaatcttcc taaagcacca gatgctattg
    17041 tcattgttgc aaccttgcgc gcccttaaaa tgcatggagg tgtcgccaaa tcagatttag
    17101 ccgctgaaaa ttgtgaggct gttcgcttag gatttgccaa cttaaaacgt cacgtggaaa
    17161 acatgcgcca attcaaagtt ccagttgtgg tggctatcaa tgaatttgta gcagataccg
    17221 aggctgaaat tgctacctta aaagcgcttt gtgaagagat taaggttcca gtagaattag
    17281 ccagtgtttg ggcaaatgga gctgagggag gcttagcatt agctaaaaca gtggttcgtg
    17341 tgattgatca agaagctgct gactacaaac gtctctattc agatgaggat actttggaag
    17401 aaaaagtgat caatatcgtt acccagattt atggtggcaa agctgttcaa tttggcccca
    17461 aggccaaaac acaattgaag cagttcgcag aattcggttg ggataaattg cctgtttgta
    17521 tggctaagac ccaatacagt ttttcagata acccatcctt gcttggagcg ccaaccgatt
    17581 ttgacattac cattcgtgaa tttgttccta aaacaggagc aggttttatt gttggtttaa
    17641 caggtgatgt gatgaccatg cctggtttgc ctaaagttcc agctgccatg gcaatggatg
    17701 tagcagaaaa tggcacagcc ctcggtctct tttaggaaaa attgctcgaa taattcgagc
    17761 aagcgctcct ttcttcccgc tttactgtga tataataagg taaatgagat tttggaggga
    17821 tgattatcaa aaagaaagca aaagtaaaat atttgctcca taaagggaaa catggatttt
    17881 taagaggaat ttttagtaga acaacaatca ttgtattatt aattattttg caattagttt
    17941 tcttatttc
//
LOCUS       DAUNLR010000035        17733 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUNLR010000035 DAUNLR010000000
VERSION     DAUNLR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17733
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.035"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            577..3603
                     /locus_tag="VLL59_001216"
     CDS             577..3603
                     /locus_tag="VLL59_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HER6509340.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSDPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTIGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKTTKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPTTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            3623..4024
                     /locus_tag="VLL59_001217"
     CDS             3623..4024
                     /locus_tag="VLL59_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HER6509341.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINNGSN"
     gene            complement(4204..5079)
                     /locus_tag="VLL59_001218"
     CDS             complement(4204..5079)
                     /locus_tag="VLL59_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HER6509342.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILIGGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCTLHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIEVN"
     gene            5215..5736
                     /locus_tag="VLL59_001219"
     CDS             5215..5736
                     /locus_tag="VLL59_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HER6509343.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHLLKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVLLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            5951..6469
                     /gene="rimM"
                     /locus_tag="VLL59_001220"
     CDS             5951..6469
                     /gene="rimM"
                     /locus_tag="VLL59_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HER6509344.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DQFVQEVTIVSHRKQKNFDIIKFKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYH
                     QIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            6459..7190
                     /gene="trmD"
                     /locus_tag="VLL59_001221"
     CDS             6459..7190
                     /gene="trmD"
                     /locus_tag="VLL59_001221"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HER6509345.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     EHYNFSEEERKLLDKIKEALGQGED"
     gene            7190..8182
                     /locus_tag="VLL59_001222"
     CDS             7190..8182
                     /locus_tag="VLL59_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HER6509346.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGAELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEKNFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            8360..9418
                     /locus_tag="VLL59_001223"
     CDS             8360..9418
                     /locus_tag="VLL59_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HER6509347.1"
                     /translation="MTTTDKETFSSFINKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            9431..10354
                     /locus_tag="VLL59_001224"
     CDS             9431..10354
                     /locus_tag="VLL59_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HER6509348.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     IVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQV
                     ADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            10610..11323
                     /locus_tag="VLL59_001225"
     CDS             10610..11323
                     /locus_tag="VLL59_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HER6509349.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGIDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            11320..12231
                     /gene="pfkB"
                     /locus_tag="VLL59_001226"
     CDS             11320..12231
                     /gene="pfkB"
                     /locus_tag="VLL59_001226"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HER6509350.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLNAEGVKTDFVKGDQDTRINVKIKSQEETEIN
                     GQGPVISREQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            12228..14174
                     /locus_tag="VLL59_001227"
     CDS             12228..14174
                     /locus_tag="VLL59_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HER6509351.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVSNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKTILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            14267..14866
                     /locus_tag="VLL59_001228"
     CDS             14267..14866
                     /locus_tag="VLL59_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HER6509352.1"
                     /translation="MKVKKRRRRAKSSINRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            15018..15725
                     /locus_tag="VLL59_001229"
     CDS             15018..15725
                     /locus_tag="VLL59_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HER6509353.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(15782..16093)
                     /locus_tag="VLL59_001230"
                     /pseudo
     CDS             complement(15782..16093)
                     /locus_tag="VLL59_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(16297..16662)
                     /locus_tag="VLL59_001231"
     CDS             complement(16297..16662)
                     /locus_tag="VLL59_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509354.1"
                     /translation="MPSTDDGILRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEF
                     DFKIRKFLMESKEIHLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVFKKYKD
                     NKTINMKDFSHFDIYLWTK"
     gene            complement(16682..17701)
                     /gene="ideS"
                     /locus_tag="VLL59_001232"
     CDS             complement(16682..17701)
                     /gene="ideS"
                     /locus_tag="VLL59_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin G-degrading enzyme IdeS"
                     /protein_id="HER6509355.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPPAKFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKDQIKRYLEEHPEKQKINFNGEQMFDVKEAIDTKNHQLDSKLFEYFKEKA
                     FPYLSAKHLGVFPDHVIDMFINGYRLSLTNHGPTPVKEGSKDPRGGIFDAVFTRGDQS
                     KLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGN
                     LKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQDS
                     WNQTI"
BASE COUNT         5686 a         2893 c         3574 g         5580 t
ORIGIN      
        1 tattctttac attctgatga aaatacaaat tatcctaaca tgatgtattg aaaggggaaa
       61 tagtttatgt tagtatactg attaagtgaa gctgtaatga ggcttatacg atcaaaaaag
      121 ttagagtaac tttataaaac agtggtgttg aagcaagttt agcttcttct cagaaataga
      181 ttatctataa aaaatcccaa aagtagtttg tttccagtta atgaacttct tttgggaagg
      241 cttttttgct gatcgccact tcacttgtat atcgggaaca ttcacgctaa gatgtataag
      301 ttgaatcgtt tgtctatggc ttgatgaaaa ttaatcaaaa gataatgttc aactctataa
      361 ttagtacaag caaaatgaga taacttattc attagtaagc ataagatata acaagagaaa
      421 ttaccttaaa acaggaagta ctagagtatt taaaataagt gatagacttg gatattatta
      481 ggtcgactag tgtccttttc aataatttaa tatcgttatt attagtatca gccaatcaaa
      541 tgtggataag ttggctttta gaaaggtttt accacaatga agaaacatct taaaacagtt
      601 gccttgaccc tcactacagt atcggtagtc acccacaatc aggaagtttt tagtttagtc
      661 aaagagccga ttcttaaaca aactcaagct tcttcatcga tttctggcgc tgactacgca
      721 gaaagtagcg gtaaaagcaa gttaaagatt aatgaaactt ctgaccctgt tgatgataca
      781 gtcactgact tattttcgga taaacgtact actcctgaaa aaataaaaga taatcttgct
      841 aaaggtccga gagaacaaga gttaaaggca gtaacagaga atacagaatc agaaaagcag
      901 atcacttctg gatctcaact agaacaatca aaagagtctc tttctttaaa taaaacagtg
      961 ccatcaacgt ctaattggga gatttgtgat tttattacta aggggaatac ccttgttggt
     1021 ctttcaaaat caggtgttga aaagttatct caaactgatc atctcgtatt gcctagtcaa
     1081 gcagcagatg gaactcaatt gatacaagta gctagctttg cttttactcc agataaaaag
     1141 acggcaattg cagaatatac cagtagggct ggagaaaatg gggaaataag ccaactagat
     1201 gtggatggaa aagaaattat taacgaaggt gaggttttta attcttatct actaaagaag
     1261 gtaacaatcc caactggtta taaacatatt ggtcaagatg cttttgtgga caataagaat
     1321 attgctgagg ttaatcttcc tgaaagcctc gagactattt ctgactatgc ttttgctcac
     1381 ctagctttga aacagatcga tttgccagat aatttaaaag cgattggaga attagctttt
     1441 tttgataatc aaattacagg taaactttct ttgccacgtc agttaatgcg attagcagaa
     1501 cgtgctttta aatcaaacca tatcaaaaca attgagttta gaggaaatag tctaaaagtg
     1561 ataggggaag ctagttttca agataatgat ctgagtcaac taatgctacc tgacggtctt
     1621 gaaaaaatag aatcagaagc ttttacagga aatccaggag atgatcacta caataaccgt
     1681 gttgttttgt ggacaaaatc tggaaaaaat ccttatggtc ttgctactga aaatacctat
     1741 gttaatcctg ataagtcact atggcaggaa agtcctgaga ttgattatac taaatggtta
     1801 gaggaagatt ttacctatca aaaaaatagt gttaccggtt tttcaaataa aggcttacaa
     1861 aaagtaaaac gtaataaaaa cttagaaatt ccaaaacagc acaatggtgt tactattact
     1921 gaaattggtg ataatgcttt tcgcaatgtt gattttcaaa ataaaacttt acgtaaatat
     1981 gatttggaag aagtaaagct tccctcaact attcggaaaa taggtgcttt tgcttttcaa
     2041 tctaataact tgaaatcttt tgaagcaagt gacgatttag aagagattaa agagggagcc
     2101 tttatgaata atcgtattga aaccttggaa ttaaaagata aattagttac tattggtgat
     2161 gcggctttcc atattaatca tatttatgcc attgttcttc cagaatctgt acaagaaata
     2221 gggcgttcag catttcggca aaatggtgca aataatctta tttttatggg aagtaaggtt
     2281 aagaccatag gtgagatggc atttttatca aatagacttg aacatctgga tctttctgag
     2341 caaaaacagt taacagagat tcctgttcaa gccttttcag ataatgcctt gaaagaagta
     2401 ttattaccag catcactgaa aacgattcga gaagaagcct tcaaaaagaa tcatttaaaa
     2461 caactggaag tggcatctgc cttgtcccat attgctttta atgctttaga tgataatgat
     2521 ggtgatgaac aatttgacaa taaagtggtt gttaaaacgc atcataattc ctacgcacta
     2581 gcagatggtg agcattttat cgttgatcca gataagttat cttctacaat ggtagacctc
     2641 gaaaagattt taaaactaat cgaaggttta gattattcta cattacgtca gactactcaa
     2701 actcagttta gagacatgac tactgcaggt aaagcgttat tgtcaaaatc taacctccga
     2761 caaggagaaa aacaaaaatt ccttcaagaa gcacaatttt tccttggccg cgttgatttg
     2821 gataaagcca tagctaaagc tgagaaggct ttagtgacca agaagacaac aaagaatggt
     2881 cagttgcttg aaagaagtat taacaaagcg gtattagctt ataataatag cgctattaaa
     2941 aaagctaatg ttaagcgctt ggaaaaagag ttagacttgc taacaggatt agttgaggga
     3001 aaaggaccat tagcgcaagc tacaatggta caaggagttt atttattaaa gacgcctttg
     3061 ccattgccag agtattatat cggattgaac gtttattttg acaagtctgg aaaattgatt
     3121 tatgcacttg atatgagtga tactattggc gagggacaaa aagacgctta tggtaatcct
     3181 atattaaatg ttgacgagga taatgaaggt tatcatgcct tggcagttgc cactttagct
     3241 gattatgagg ggctcgacat caaaacaatt ttaaatagta agcttagtca attaacatct
     3301 attcgtcagg taccgactgc agcctatcat agagccggta ttttccaagc tatccaaaat
     3361 gcagcggcag aagcagagca gttattgcct aaaccaggta cgcactctga gaaatcaagc
     3421 tcaagtgaat ctgctaactc taaagataga ggattgcaat caaacccaac aacgaataga
     3481 ggacgacact ctgcaatatt gcctaggaca gggtcaaaag gcagctttgt ctatggaatc
     3541 ttaggttaca ctagcgttgc tttactgtca ctaataactg ctataaaaaa gaaaaaatat
     3601 taaattgatt taaggagaaa aaatgataac acaagaaatg aaagatctta ttaataacca
     3661 attagcaatg gttgcgacgg ttgatgccaa aggtcaaccc aatattggtc caaaacgttc
     3721 tatgcgtctc tgggatgata aaacatttat ttataatgaa aatacagatg gtcaaactcg
     3781 tattaacatt gaagataatg ggaaaattga aattgccttt gttgatcgtg agcgcctttt
     3841 aggttacagg tttgtaggaa ctgctgaaat tcaaacagaa ggtgcttatt acgaagcagc
     3901 gaaaaaatgg gcacaaggac gcatgggggt accaaaagca gttggtatta ttcatgtcga
     3961 gcgtattttt aatttacaat ctggtgctaa tgcaggtaaa gaaataaaca atggaagtaa
     4021 ctaaaattaa ctgtaacagt atttaggacc cttattttaa acgctaaaaa acaagcatac
     4081 tcttttttac agcatagtga ctatgttgta aaaaggggta tgcttattag gtgctcttaa
     4141 tatttctaga taactgcacc taataagttt tcaatagact tatagcacat taattgactt
     4201 caattagttg acttcaatac tagaaagaga agaacagtga tgttggtgtt cgtttaaaga
     4261 agtatcgatt tccacagtga ctgagtttat attgtacctt tgacaaatca gtctaataga
     4321 ttttttgcaa tgtttttcag tggtggattc tctcaagcag caatgtatag ttgctctatg
     4381 gtcaatacca tccatcgacc aaacattaag ctgattaaca gacactatat gaggaagttg
     4441 gctgagttca tggtgcaaag tgcaatagtc tatcgaatca ggaacaccat ctaaaaaaat
     4501 gttagcagtt gctactaact ttggaagagc tttagataat ataaaagaag caatggcaat
     4561 tgataataaa ggatcaagaa tgtaccaagg tttccatttt aagatcagtg acagtatgat
     4621 aatggctaac cacccaagga tatcttctaa aaagtgaagg cttaatattt cttcattttt
     4681 tgtctggtta gagtgaatga tgaagctagc aaatccattg attataattg caaaaatagc
     4741 taaaacgaac ataccgtcat aattaacaat agtaggatgc cataattttg gtatcgtttc
     4801 aatcattact aataatgacc cgccaataag tattagattt gtcgttagcg ctcctaaaag
     4861 gctaaatcgc ttatagccta gtgaaaaatt tggactctct tttttaacag cctttctttc
     4921 taagatagct gagataccaa tagcaatggc atctccaaaa tcgtggacag catctgctaa
     4981 aatagcaccc gaaaagaata atgtcccaaa aataaattca atgagggaaa aactaagatt
     5041 taatataaaa ataatggtga cttttttact tgctggcata attttctcct tttgttatac
     5101 tggtaatatg tatagtagaa ttctttattc tattatctaa aagttaaaat acaattacta
     5161 taaccaaaaa tgagcacctg ttcaatagtg aacaacattt agaaagtgtc cgatatgaca
     5221 aaagacagac aaatcaaaaa aacaaaaaca gctatctata gtgcttttat tgctttatta
     5281 caaaaaaaag aatattcgaa aataactgtt cgagatatga ttacacttgc taatgtaggg
     5341 agatcaacct tttatgcaca ttatgaaagc aaagaaatgt tactaaaaga actctgtgaa
     5401 gaactttttc atcatttgtt taggcaaaaa agaaatgtga cttttgagga ctatttggta
     5461 catcttttaa agcattttga acaaaataaa gacagcattg cgacgttgtt actttctaat
     5521 gatccctatt ttttattaag atttaaaaac gaactagaac atgatgttta ccctaacttg
     5581 cgctgcaagt atatcgacaa aacgactatt ccagaagtat tgctaaaaca atttgttcta
     5641 tctagtttta tagaaacctt aaaatggtgg ctccatcaaa ggcaaaggat gtctgcaaat
     5701 gaactattaa agtattattt agagctcata aaataatgac tagtgagtca tcttgccaaa
     5761 ttcaattttt taatacagac ggattttaac aatttaacag agaaagacaa aactgtaagt
     5821 gcaaaataga ctataacgtg ataaaataat aggtaatttg gttctgaaaa agaagtgtct
     5881 atcaaacttt agaatcaaga gaggtcgcta aagtgacgtg agataaagag ttaacgattt
     5941 aggagctacc atggaatatt ttaatgttgg aaaaattgtc aacacgcaag gcctgcaagg
     6001 agagatgcgc gtgttgtctg tcagtgattt tgctgaggaa cgctttaaaa aaggctcaca
     6061 attagctttg tttgatgaca aagaccagtt tgttcaagag gtcacgattg ttagccatag
     6121 aaagcaaaaa aactttgata tcatcaaatt taaagacatg tatcatatta atgctattga
     6181 aaagtacaag ggatacactt taaaggtctc aaaagacaat caaggggatt tacaagaagg
     6241 agaattttac taccatcaga ttatcggtat ggctgtttat gaaaaggacc ggttgattgg
     6301 ctatgtcaag gaaatcttgc agccaggtgc taatgatgtt tgggtagtga aacgccaagg
     6361 aaaacgagac ttgctcttac catatattcc cccagtagtt cttaacgtag atgttcctaa
     6421 caagcgcgtg gatgttgaat tgatggaagg cttagacgat gaagattgat attttaaccc
     6481 tttttcctga aatgtttgcc cccctagaac attccattgt aggcaaagca aaagaaaaag
     6541 gattacttga cattcactac cataactttc gagattatgc tgaaaaagct cgtcatgtgg
     6601 atgacgaacc ctatggtggg ggccaaggca tgttattgag agcacagccc atttttgaca
     6661 ccattgaaca gattgaagcc aaaaaaccaa ggattattct tttagatcca gcaggtaaac
     6721 cctttactca ggcttatgct gaagaattag ctcttgagga agagttaatt tttatttgtg
     6781 gtcattatga aggttatgat gagcggatta agaccttggt gacggatgaa atttcattag
     6841 gtgactttgt attaacagga ggtgagttgg cggccatgac tatggtggat gcgaccgtca
     6901 ggttaattcc acaggtactt gggaaagaaa gtagccatca ggacgattct ttttcatcag
     6961 gacttttaga ataccctcaa tacacaagac cttatgatta tcgtggtatg acagttccag
     7021 atgttctaat gagtggtcat cacgaacgta ttcgcttgtg gcgtctagaa gaaagtctca
     7081 gaaaaaccta tttaaggcgg ccagatttac ttgaacatta caatttttcc gaggaagagc
     7141 gcaagctatt ggataagatt aaagaagcat tgggtcaagg agaagattag tgaaagataa
     7201 agcatatgat attacgatta ttggtggtgg tccaataggt ttatttgcag ccttttatgc
     7261 aggtcttagg ggcgtaacag taaagattat tgagagtttg tcagaacttg gtggacagcc
     7321 tgccattctt tatcccgaga aaatgattta tgatattcca gcttatccat ctttaacagg
     7381 tgctgagttg acagaaaatt taataaaaca attaagccgt tttgaagatc gtacaaccat
     7441 ttgtttaaaa gaagaagtat taacctttga caaggttaaa ggtggttttt cgattaggac
     7501 taataaggca gagcattttt caaaagccat tatcattgct tgtggaaatg gcgcttttgc
     7561 accaagaact ttagggttag aaagtgagaa aaactttgct gatcataacc ttttttataa
     7621 tgttcaccag ttggaccagt ttgcgggaca aaaagttgtg atttgtggtg gtggagattc
     7681 agcagttgat tgggctttgg ctttagaaga tattgctgag agtgtgacgg ttgtgcaccg
     7741 tcgtgatgct ttcagagcac atgaacacag tgtggaatta ttgaaagcat caacggtcaa
     7801 cctcttaaca ccttatgtgc caaaagcatt gaaaggaatt ggaaacctgg ctgaaaaatt
     7861 agttattcaa aaagtgaaag aagatgaagt gttagaactt gaattggaca gtcttattgt
     7921 tagttttggt ttttcaactt ctaataagaa tttgaaaaat tggaatctcg actataagcg
     7981 ttcaagtatt actgtttcac cactttttca aacaagtcaa gaaggtattt ttgccattgg
     8041 tgatgcagcc gcttataatg ggaaagtgga tttgattgct actggttttg gcgaagcacc
     8101 aacagcagtt aatcaggcca ttaactatat ttatccagat cgagataacc gtgtggtgca
     8161 ttcaacctct ttaattgact aagggagtcg gaagtttcaa gagcagtagc aacagctaat
     8221 attcagtttg tcaggatagg acaaatggtt tttacctaag tcttcgtgac aagttttata
     8281 ctttgtgata aaatagtcat tgtgaaaaaa gtgtgatggt tttcacagat taacacatta
     8341 caatgaaaag gggtctatca tgacaacaac agataaagag acatttagtt cttttataaa
     8401 taaggtcttg gctggtacag cgattgctat cgttgtggca ctcattccaa atgctatttt
     8461 agcgactttc ttaaaaccgc ttttgccaaa tatggcagct gctgaatttt tacacattgt
     8521 gcaagtcttc caattcttca cgccgattat ggctggtttc ttgattgggc aacaatttaa
     8581 gtttaatcct atgcaacagt tggctgttgg tggagctgct tatatcggtt ctggagcctg
     8641 ggcttataca gaagtcattc aaaaaggtgt ggcgacagga acattccaac ttagaggtat
     8701 tggagactta atcaatatga tgattacagc tagccttgcg gttttagctg tgaaatattt
     8761 tgggaataaa tttggctctt taaccattat cttgttacct atcactatag gaactggcgt
     8821 aggttatatt ggttggaaat ttttgcctta tgtgtcttac gtgacaaccc tgatcggaca
     8881 agggattaat tcttttacaa ccttacaacc tattttaatg tctattttaa ttgcagttgc
     8941 tttctcgctt atcattgtta gtccgatttc aactgttgca atcggtttag ctattgggct
     9001 taatggaatg gctgcgggag cagcttctat gggaattgca tcgacagcag cagtcttagt
     9061 gtgggcgacg cttaaagtta ataaatctgg tgtaccaatt gctatcgcac ttggggctat
     9121 gaaaatgatg atgccaaact tcttgaaaca tcctatcatg gctattccga tggtgttcac
     9181 tgcagcaatt agctcattaa cagtaccatt gtttaatctt gttggaacac cagcttcatc
     9241 tggttttgga ttagttggtg cagtaggtcc gattgcttct ttagcaggtg gtagctcaat
     9301 acttattatt atccttgctt ggatcattgt tccgtttgcg gttgcttttg cggcgcataa
     9361 ggtttctaaa gatattctaa aactttataa agaagacatt ttcgtctttg aaggctaata
     9421 ggaggaaaat atgttagttt atattgctgg ctcaggagcc atggggtgcc gttttggtta
     9481 ccaaatttca aaaacaaata acgatgtgat tttgttagat aactgggaag atcatatcaa
     9541 tgccattaaa gaaaacgggt tgattgtaac aggtgatgtg gaagaaacag ttaagcttcc
     9601 tattatgaaa ccgactgaag ccactcaaga agccgatttg attatcttgt ttacaaaagc
     9661 aatgcagttg ccacaaatgc ttcaagacat taaaggcatt attggaaaag aaaccaaagt
     9721 gctttgcctt ttaaatggtc ttggacacga agacgttatt cgtcagtaca ttccagagca
     9781 caacattttg atgggggtca ctgtctggac tgctggtcta gaaggaccag gtcgtgctca
     9841 tcttcaagga gttggtgctc ttaacttaca aagcatggat ccaagcaatc aagaagctgg
     9901 acaccaagtg gctgatttgt taaatgaagc taacttgaat gcgacttatg atgagaatgt
     9961 tgtgccaaac atctggcgga aagcttgcgt gaatggtacc atgaattcga cttgtgctct
    10021 tttagattgt acgattggcg aattatttgc cagtgaagat ggtctcaaaa tggtaaaaga
    10081 aatcatccat gagtttgtta tcgttggtca agcagaaggt gtcgaactaa acgaagaaga
    10141 aatcacacaa tatgtaatgg atacatctgt taaagctgct caccattacc catcaatgca
    10201 ccaagacctt gtgcaaaatc accgattgac tgaaattgat tttatcaatg gtgcagtcaa
    10261 taccaaaggc gaaaagcttg gtatcaatac tccatactgc cgtatgatta cagagctagt
    10321 tcacgctaaa gaagcagtgt tgaacatcca ataaacgcta tcaaatcgtt atactcaata
    10381 ttatggctaa agctttaata ttgagttttt tgttatgctg atagtatttt tcttaggcgt
    10441 cattatttgt gagcctagat tatgagttaa taaaagaaat aataattggt agaatttgat
    10501 agattttgaa aggttatgct tgacttttag ttataaaata gtataataat tgtaaacgat
    10561 ttcagttagg ggtggttcta tcttaaaatc aaaacgaaaa caattaatta tggcaaagat
    10621 cactgaagaa aactatgttt ctttagagga tttaatgcaa ttactcaact cctctgagtc
    10681 tactatccgc agagatctag gagagttgga gcaagaagga cggctacatc gtgttcatgg
    10741 aggtgctgaa ctttttcact ctttacaaga ggaactttct aaccaagaaa agtctgtcaa
    10801 aaacagtcat attaaaaaag ctattgcgca aagagcctct cagtttatct atgacaacga
    10861 tgtgatcttt attgatgctg ggacaacgac tgaattttta ttaccttttt tacaagctaa
    10921 aaatttaact gtagttacta attctattca tcatgctgct agattagttg aactctctat
    10981 tgagacgatt attgtaggtg gttatgtcaa acaaacgacc gatgccagta ttggtaatgt
    11041 agctttggaa cagattaggc agatgaattt tgacaaggca tttcttggaa tgaatggtat
    11101 tgatgattct tacctgacga ctcctgatat ggaagaagca gttattaaaa aagcggttct
    11161 gtcaaatgca aaattagctt acattttagt agatggcact aaaattggtc aggtatcgtt
    11221 tgtaaaagta gctcctatta atgatgtgac tattattaca ttaggaggat cagcaagtat
    11281 tcttaaacaa ataaaggaaa aggcaaaggt gattgaatta tgatttatac cgtgacctta
    11341 aacccttcta ttgactttat tgtcagaatt gaccaaataa atcttgggtc agtgaatcgc
    11401 atggcgagtg atgataagtt tgctggaggt aaaggtatta atgtgagtcg catcttgcaa
    11461 cgtttagaca ttgctagcac ggcgacagga ttcttgggtg gttttacagg acgttttatc
    11521 gaagaaagtt tgaatgcaga aggcgttaaa actgattttg taaaaggtga tcaagatact
    11581 cgaatcaatg ttaaaatcaa gtcacaagaa gagactgaaa taaatggtca aggacctgtc
    11641 attagtcggg aacaactgga ggatttgaaa actaagcttt cccagctaac agcagaggat
    11701 acagttgtct ttgcaggttc agcgccagct aatcttggca atgctgttta taaggaatta
    11761 cttcctttag ttaggcaaag cggtgctcag gtggtttgtg attttgaagg tcagacttta
    11821 atagatgcgc ttgcatataa tcctctgttg gttaaaccta ataatcatga actagaagct
    11881 atttttggta cgattctgac tagtcttgat gatgttgaaa cctatgcccg tcgtctttta
    11941 gagatgggtg ctcaaaacgt catcatttca atggctggtg atggtgcttt gctggttact
    12001 aaagaagcga cttattttgc taaaccgatt aagggagaag ttaaaaattc tgtcggtgct
    12061 ggtgattcga tggttgctgg ctttacaggc gaatttatga agagtcaaaa tccaatagaa
    12121 gccttaaaat ggggcgtggc ttgtggtaca gcgacggctt tctctgatga cttggcgaca
    12181 attgcattta ttaaggaaac atatcataaa gttgaggtag aaaaacgatg aaaattcaag
    12241 atttattgag aaaagatatt atgattctcg atttacaggc tatttctaaa gaagttgcca
    12301 ttgacgagat gattactaaa ttagttgaaa aagatattgt acatgatttt gatgtcttta
    12361 aaaagagtat catgacacgt gaagaacaaa catcaacagg gcttggtgat gggattgcca
    12421 tgcctcattc taaaaatatt gtagtagata aaccagcggt cttgtttgcg aaatcaaata
    12481 aaggtgtgga ttataaggct ttagatggtc aaccaacgga tctcttcttt atgattgctg
    12541 cgcctcaagg agcaaatgat actcacttgg ctgcgctagc agaattatca caataccttt
    12601 tgaaagacgg ctttgctgat aaacttcgtg ctgcagcgac accagaagca gtcattgctg
    12661 tttttgatga agcgtcaaca gctaaagaag aagtggttgc tccaacaagt ggtcaagact
    12721 ttatcgttgc tgttacagct tgtccgacag gaattgctca cacttatatg gcagaagagg
    12781 ctttgaaaaa acaagctgca gaaatgggag tagctattaa agttgaaaca aacggtgctt
    12841 ctggtgtggc taatcgttta accgctgaag atattcagag agctaaagga gttattgttg
    12901 cagctgataa agcggttgaa atggaccgtt ttgatggtaa acaattcatt gctcgccctg
    12961 ttgcagatgg tatcaagaaa agtcaggaat tgatttcttt gattttaaac aatgaaggaa
    13021 acacttatca tgctaaaaat ggaaaatctg aaacagcagt atcaactgag aaaacaagtt
    13081 taggcggtgc tttctataaa cacttgatgg gcggtgtctc acaaatgttg ccatttgtta
    13141 ttggtggcgg gattatgatt gctctagcat ttttattgga taacatgctt ggtgtgtcaa
    13201 atgatcagct tggaagtctt ggatcctatc atgaaatagc agctattttt atgaacattg
    13261 gtggagcagc cttttccttc atgttaccag tactagcagg ttatatcgct tattctattg
    13321 ctgaaaaacc gggcttagta gctggttttg tggcaggtgc cattgcctca aatggtcttg
    13381 cttttggtaa ggtaccattt gcagcaggag gagaagtgag cttgggctta acgggcgtgc
    13441 catcaggttt ccttggggcg cttgtgggtg gtttccttgc cggtggtgtt attcttgccc
    13501 ttcgtaaatt gttggcaggc ctaccacgtt ctctagaagg ggttaaaact atcctccttt
    13561 acccattact tggcgtcctt gtcactggtt tcttgatgct ttttgtcaat attccaatgg
    13621 cagctattaa tacagccctt aatgatttct tacaaggtct ttcaggaagc tctgctgtcc
    13681 ttatgggact tcttgttggt ggaatgatgg ctgttgacat gggtggtcct gttaataagg
    13741 cagcttatgt ttttggtaca ggaactttag cagctactgt ggcaaatggt ggttcggtcg
    13801 ttatggccgc tgttatggca ggtggtatgg tacctcctct tgctgttttt gtagccactc
    13861 tcttgtttaa agataaattt accaaagaag aacgtgaatc aggcttgaca aatattgtta
    13921 tgggactttc attcatcacc gaaggagcaa ttccgtttgg tgcagctgac ccagcacgtg
    13981 cgattcctag ctttatcgca ggttctgcct tgacaggagc tcttgttggt ttggctggta
    14041 ttaaattaat ggcgccacat ggtggtatct tcgtaatcgc tttaacaagc aatccaatct
    14101 tatatcttgt ctttgttgtg attggcgccc ttgtatcagg tatcttattt ggcgctcttc
    14161 gcaaaaaagc ctaaaaggta aagaactttt ttcttactaa aactagaatc tgtcaaggtt
    14221 ctagtttttt gctatactag agttaaagga taagaaatga ggacctttga aggtgaaaaa
    14281 aaggagaaga agggctaaat catcaataaa tcgacttgtc ttagggttag tattacttaa
    14341 tctgattgtt agtatgtgga cactaaaatt gggaaaccag cgattagctc cgtatgcgga
    14401 tcacgaaact ctgacatttg tcaggaagat tagtcatgct gctcaatcag tcgctcaaaa
    14461 gaaacagtta tacagttcgg tgatgatggc tcaggccatt ttagaatcca ataatggcaa
    14521 gtcacaacta agtcaaaaac cttattataa ttttttcggg attaagggga gctataaaga
    14581 acggtcagtc atttttccaa ctttagaaga cgatggacaa gggaatcttt atcaaattga
    14641 tgctgctttt cgttcctatg ggagcctgac agcttgtttt ttagattacg caagagtttt
    14701 gaatgatcca ctttatgaca aaacccacaa aaagttttgg tctcattatc aagatgctac
    14761 tgcaacctta acaggcactt acgccactga tacaacttac cataccaaat taaatgaatt
    14821 gattgaatgg tatcaactca ctaattttga tggtctaatg aaatagttat ccacaatttt
    14881 aaaaaaaatc agaagaaata tgtcgatttc aagacaaaag ttatcaatct cattaaatta
    14941 tctgtggaaa agttaattta aacgttcgtg tgctataata gaaacataga aaatgtataa
    15001 aaaaggatat gtgaataatg acaaaaaaga aaggtaagct tgtacttatc agtctttttg
    15061 ttctagcagc ttgtttagga gcttatagtg caatgagaca atctcataaa acttcaaacg
    15121 tgtcagctga gactatcgcc agttcttcaa cccgacattt tattgatgaa attggtccaa
    15181 ctgctagtac tattggtcaa gaacgtgatc tttatgcgtc tgttatgata gcacaagcga
    15241 ttttagaatc aagtaatggt aaatcaagtc taagtcaagc accttattat aattttttcg
    15301 gtattaaggg tgcctataac ggttcttctg tgacgatgtc aacttgggaa gatgatggta
    15361 atggcaatac ctatacgatt gatcaagcct ttagagctta tccaagtatt gcagactccc
    15421 ttaatgacta tgcagacttg ctaagttcta gcacttatat aggtgctaga aaatcaaaca
    15481 cgctatcgta tcaagatgct acagcagctc taactggctt atacgctaca gacaccagtt
    15541 ataacttaaa actaaataat attattgcaa cctatggttt gacggcttat gatgttgcta
    15601 atagctcagc tcaagaaact ggtctagcaa cttcgggtta tgtttggaat gagtatcgtc
    15661 gtaattacac tgatgcggag accctagcag ttgatgaggc ttgggctaaa cgcatgactt
    15721 attaatgtaa cactaacaac aatctgcttg cactgacccc aaaaaagctg gatactctat
    15781 tttaagtaaa ggatttagtt ctgtacaata cagaactaaa tccttttagt tttactttga
    15841 tatgtttatc gttgtaataa tcaatgtcat ttgtaatcgc ttattctgag tcttctagtg
    15901 atttatagtt attctcataa ccatagaaca tttctgactt taagatgcca aagaaagatt
    15961 ccatcatgct attgttagga ctgtttcttt tacgtgacat agacggacga attcctttag
    16021 agtttaggaa atgatgataa tagttgtgtt gatattgcca accttgatca ctctatcata
    16081 tagttccatc atagcattta tttggagatg tctttttcca ttattggttt aatgtgattt
    16141 aagcaaggtt attagctaaa cttaatgcca gacaaaaaca ccccaattat tagatttttt
    16201 gtctaacttt tggggcgcaa ttcaatctga gcagttttag atttggtatc aatgttatta
    16261 taggtcaatt gatcatattt atccaaagct tttagcttat ttagtccaaa gataaatatc
    16321 aaaatggctg aaatctttca tgtttatagt cttattgtct ttatattttt taaagacatc
    16381 agatctggtg ctattgggct ttgcgtcata taaattgatt ttttcatgtt tcctattttt
    16441 actgtgaatt tctaaactcc cccttatata aggagactta gtcaaatgaa tttcttttga
    16501 ttccatcaaa aattttctta ttttaaaatc gaactcttga atcgtaacaa tatccttatc
    16561 gatttttata ggatttatta atgttttttg ctgttgccca tctataaaaa aattccctgc
    16621 aatagtatta gtccttagaa taccatcatc tgttgaaggt attctttctt attgatacgc
    16681 tttaaatagt ctgattccaa ctatcttgcc ctgttgaaag tgtaaataac cctagtactt
    16741 gagcaccaat attatcttct tttatttctt tagcagaaat agctactttt ccagcggaat
    16801 taacaccaac aaagtatttc ttcataccaa tagatgcatt actatcagag tctgttacat
    16861 aaatagcttt aaggttcccg ttagaatcga agtcagctcc ccacaggttt ataacatggt
    16921 tgatgcgtac gttagcgtag gtgtgtgata ggcctagagc cttgccttcg gttaactctt
    16981 tcttaatgag atcactgatt tctttgagat ttttttcttt aaaatcatga cgacttgtca
    17041 atagcttact ttgatcacct cttgtaaata cggcgtcaaa aataccacct cggggatctt
    17101 tactaccttc ttttactggc gttggaccgt ggttagttag actaaggcgg tagccgttaa
    17161 tgaacatatc aattacatga tcagggaaaa ctcctaggtg tttagcagat agataaggga
    17221 aagctttttc tttaaaatat tcaaataatt tactatctag ctggtggttt ttagtgtcga
    17281 tagcttcttt tacgtcaaac atctgttcgc cattgaagtt tattttttgc ttttctggat
    17341 gctcttccaa ataacgttta atttggtctt tgttttgatc gaaccaccag tgaagcatat
    17401 tccctgctgt ggcagccccg caaagaagat catcttttcc attgaatgtt ttggtaatat
    17461 cataccatcc ttggttagca acataaggag cgtgaaaaac atcttcgcct tgagtgaatt
    17521 ttgctggagg agtaactcct ttggtccaaa cggaagtaac gtgataaggt gttacttccg
    17581 aatatctaat ctcttgatta gcagaaaaac tatctgctat aacaccacga tctaccgata
    17641 gagcaaataa agtcactgct gctaatactg cagctgaagt tgaatagcat ctttttctca
    17701 taagaatacc tttttctata taattttatg ata
//
LOCUS       DAUNLR010000036        16954 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUNLR010000036 DAUNLR010000000
VERSION     DAUNLR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16954
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.036"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            32..445
                     /locus_tag="VLL59_001233"
     CDS             32..445
                     /locus_tag="VLL59_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HER6509356.1"
                     /translation="MKLNAIHHVAIIVSDYNLSKNFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            1060..1428
                     /locus_tag="VLL59_001234"
     CDS             1060..1428
                     /locus_tag="VLL59_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509357.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKNSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEESLGQVKEKVEGIGEATSQ
                     TIQSKMEKLTSDKTDADDEK"
     gene            complement(1475..2386)
                     /locus_tag="VLL59_001235"
     CDS             complement(1475..2386)
                     /locus_tag="VLL59_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HER6509358.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADITAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(2503..3153)
                     /locus_tag="VLL59_001236"
     CDS             complement(2503..3153)
                     /locus_tag="VLL59_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HER6509359.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(3150..3590)
                     /locus_tag="VLL59_001237"
     CDS             complement(3150..3590)
                     /locus_tag="VLL59_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HER6509360.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLLQEVTQ"
     gene            3809..4657
                     /gene="ylqF"
                     /locus_tag="VLL59_001238"
     CDS             3809..4657
                     /gene="ylqF"
                     /locus_tag="VLL59_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HER6509361.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELIADKIKRLRDRGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTHY
                     PSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYSLFVKEVRDGKLGQYTLDQV
                     GDMDAD"
     gene            4647..5438
                     /locus_tag="VLL59_001239"
     CDS             4647..5438
                     /locus_tag="VLL59_001239"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HER6509362.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKA
                     IQADLAEEERLEAMLSYEKALYKEGYQAIAGIDEVGRGPLAGPVVAACVILPQHCKIK
                     GLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            5503..6339
                     /gene="dprA"
                     /locus_tag="VLL59_001240"
     CDS             5503..6339
                     /gene="dprA"
                     /locus_tag="VLL59_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HER6509363.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVRSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            6446..8575
                     /gene="topA"
                     /locus_tag="VLL59_001241"
     CDS             6446..8575
                     /gene="topA"
                     /locus_tag="VLL59_001241"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HER6509364.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPEDKNRVVFNEITKDAVKNAFVEPRQIDMNLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFVPEEYWSIDG
                     LFKKGTKKFQASFYGLDGKKMKLSNNDDVKAVLAKLKGDDFLVSKVEKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKNKMLP
                     KMEEGENVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPICHKGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRDCPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            8710..10056
                     /gene="trmFO"
                     /locus_tag="VLL59_001242"
     CDS             8710..10056
                     /gene="trmFO"
                     /locus_tag="VLL59_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HER6509365.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHDALTNAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRICDKKERYEAIASRALADLDTCLASL"
     gene            10209..11615
                     /locus_tag="VLL59_001243"
     CDS             10209..11615
                     /locus_tag="VLL59_001243"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HER6509366.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQARQKHLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            11658..11972
                     /locus_tag="VLL59_001244"
     CDS             11658..11972
                     /locus_tag="VLL59_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509367.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            11972..12322
                     /locus_tag="VLL59_001245"
     CDS             11972..12322
                     /locus_tag="VLL59_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HER6509368.1"
                     /translation="MKRYEVTVNGQVYEVSLRELADGETVEVSQPAAPATEKEMNANA
                     AGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            12332..13462
                     /locus_tag="VLL59_001246"
     CDS             12332..13462
                     /locus_tag="VLL59_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HER6509369.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(13663..14547)
                     /gene="citG"
                     /locus_tag="VLL59_001247"
     CDS             complement(13663..14547)
                     /gene="citG"
                     /locus_tag="VLL59_001247"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HER6509370.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(14540..15235)
                     /locus_tag="VLL59_001248"
     CDS             complement(14540..15235)
                     /locus_tag="VLL59_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6509371.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(15393..16796)
                     /locus_tag="VLL59_001249"
     CDS             complement(15393..16796)
                     /locus_tag="VLL59_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HER6509372.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
BASE COUNT         5437 a         3164 c         3445 g         4908 t
ORIGIN      
        1 tcagcctact ttttttgaaa ggagaaatat gatgaaacta aatgccattc atcacgttgc
       61 tattattgta tctgattata atctgtcaaa aaatttttat gtgaataaac tcggatttga
      121 aattatcaga gaaaattatc gtcctgacaa gcatgattac aaattagatt tatcttgtgg
      181 tcgtattgaa ttggagattt ttggtaaggt gacaagtgac ccctactatc aagctcctcc
      241 taaacgtgta agtcaaccag aatttaaaag tgaggcctgt ggtttgaggc accttgcatt
      301 tcgtgttacc aacattgaga gttatgtaga tgatctaaag agcttaggaa ttccagtgga
      361 gcctatcagg catgatgatt acacaggtga gaaaatgact ttcttttttg atccggatgg
      421 tttgccttta gaattacatg aatagactta ttaggttaac gactggatcg tgctataaaa
      481 ctcgttaaaa atagttattt gttgtatctt catttgcttg attaatctct tttgatcgtt
      541 aaatgatttg gttaactttc aaagtgaaga gcaatttttg gagtaatctt gtcgaagttt
      601 tttaatagaa taactatagg aaaagcaaaa tatttgacga taaactctta cagtgttata
      661 atgacaatat aagttaataa ctgtgttgtc actttgttga aatgttttcg tattaatgtt
      721 tttttatcta ttgcgataga taattttact tcaatttttg attgaaatta ctaaaataag
      781 tgatgtggtc actttgacaa ccatttattg gtccttttag ataagacaat tttgtggctc
      841 ttcagttgaa aggatgtgtt gttgatgtta gaggaaacaa tcatgttaaa ttaactcagg
      901 cttaaagacc aaaaaaagga gtgaagtcta ttatgaaaaa aagaaatttt aaacttacag
      961 aaatgttaca attggtttta ttagtggttc ctgctgtaaa acttgctaaa aaaatgttta
     1021 acgatagtaa aacaccgtct aaaagaaagt aggtctacaa tgactaaaaa aaatcatggc
     1081 gttttttggg ggttgttgct tggatcagca gcagctagca ttgcttactt aagtttatcg
     1141 tcttccaaaa aagatcaact cttgaaaaat agtgctaaaa aaatagatga tctcaacgct
     1201 tacttgcaag ataaaagtaa gcaagttctg gatgcagtat cggaaaaagt acaagaatcc
     1261 aaagatgctg ttgaagttta cggtggtatt gccgcagaaa cagttgaaga atctttggga
     1321 caggttaaag aaaaggtaga aggaattggc gaagctacta gccaaactat ccaatctaaa
     1381 atggaaaaac tcaccagcga taagacagat gctgatgatg aaaaataggt tttaaaatac
     1441 ctttaagatt aaaaaagtgc ctaatggcac ttttttaatc ttctgttgga acaataatcg
     1501 aaatggcttt tggaatgata tctaattgaa tgggcagata gtcactttta tccccatcaa
     1561 tcctggtacg tggtaatatc gcttgttttt tagcttgtgg tagtaagcta agcgtattgg
     1621 cttgaaaatg actgatttcc tctgctttgg aaaaatcacc ctgtttaaaa tcattaatat
     1681 gccataaaaa tttaaagaaa gagacttttt tcatggtata aacttggaaa tagccatcgt
     1741 cagcttgagc accaggagaa aaagaaggaa aaccagcaat ggtatttgtc atcgtgatta
     1801 agagaaactt cgttttcagg tgaatacgat ggttgtggct aattaaagag atggcatagc
     1861 tgcgatttcg tttcagtatt cgaatactat cttttaaaaa tgctagagga ccaaagcgtc
     1921 gtttttcctc agccgttatg tcggcagcaa tatcagccag taatcctaag gttaaactgg
     1981 aaatcatgta ttgctggtta gctttgcaaa tatcaacttg tttgatttgt ccagtcaaga
     2041 tagtatccaa cgcctcagta atttgtaaag ggatatgcat agccttggca aaattattga
     2101 ctgtccctga gggcactaag cctattaaac aatgagctcc tccttcatag atgccaccga
     2161 tgattttatt tagtgtccca tcgccaccaa gagggataac caagtcaatc ttgtccttag
     2221 cagcttgttt tgctaattga aaagcctggt cagcatcttt aggggtaata acttctacag
     2281 aatcttcgga aaaaccatgt tggcaaaaat agtctttgac ttgcccagca agttggtctt
     2341 ctttctttcc agaattagga ttgtaaaaaa tccgaacggt tttcatcagg tctctccttt
     2401 gacagcttat tacttgctat ccattatacc acttctaaga attgatgtct tacatcaaat
     2461 catcacatta agcctctcaa tcagtctgag catctatttg tcttaaagca taaagaaagt
     2521 gatagcgata aattggaggg cagaggccaa taaaataaag agatgccaaa tcatgtggaa
     2581 gtagggtctt tttttggcat aaaataccgc tccaatggta taagacaagc caccaaataa
     2641 catgagaaga ccaaaagcaa gactagtttt ttgaatgatg actggcaaga taaacacaac
     2701 gagccagccc ataacgatat aaagcatcaa actgaatttt tcattgatac gtttggcaaa
     2761 aattttgtat aaaatcccaa aaagcgtaat gccccactgc aaaacaataa tgatatagcc
     2821 tagccaacca gaaacaaggg ataaggcaac aggtgtataa cttcctgcga tagcaatgta
     2881 aatcatactg tgatcaataa tgcgtagaat gtatttgtga accgaaccat aagccatgga
     2941 gtggtaaatc gtagaggaca aaaacatcaa aaagagactg atgacaaaga tggagatacc
     3001 aatagcggct ttaaggtcat aagtttgata agcatagctg gctgaaatag gaagtagaat
     3061 gagcatagca aatgctccga tagcgtgtgt cacgctgttt gctacttcct cactaaaaga
     3121 taagggtaaa ctttgtttaa aggtttggtt cattgggtca cctcctgtaa taaataaata
     3181 gttttgtggt aatctttgac cgtttgacag gcaacctgca caatcggtgg aatgtcctcc
     3241 tcaatgggag ccttctgatt ccaacaggtt acaaaagtat tgtaaagact ttcagaatca
     3301 gcctgtgcct gaagttcctc caatacgcga ctaatatctt gaataggaaa taccgtttta
     3361 aacaaactga tggcaattaa gcgcgctagt tgttgctttt ggtatttttt cttgataggt
     3421 ttagtcacat acccatgctt gacgtaatta ttaatcatag atgccgttag tgatttatta
     3481 tctgacactt ctgaaaaatc agtgcactgg ttgacataaa gtaacacttg atccaaatat
     3541 aagtctaaat cagggaggtc cttccaataa ggtaatgatg gaaaaatcat agttttgtct
     3601 ctctatctag ttttgataac tagattatat gattaatgaa aacttattgc aagcaaaaac
     3661 tgtaaagact taaaagagga aagtagaaat ggcgaagtga agctaatcat gctataatgt
     3721 taaagaattg attgggatag atgccttctg tcgcaatcag actattttat cacgaagaag
     3781 atgatgctac gaaaggaatg atacactcat ggcaatgatt caatggtttc ctgggcacat
     3841 gtccaaagcc agaagacagg ttcaggaaaa tgtaaagcat gttgactttg taactatttt
     3901 agtggatgca cgcttgccac tttctagtca aaatcccatg ctcaccaaaa ttgttggtga
     3961 taaacctaaa ttaatgattt taaataaagc tgacttggca gatgcaactc gaactaaaga
     4021 gtggaaagcc tactatgaaa gtcaaggcat taaaacacta gccatcaatt ctaaagaaca
     4081 atcaacagtt aaaaaagtaa cagaagcagc caaggaactc atagctgata aaattaagcg
     4141 cctgcgtgat cgtggtattc aaaaagaaac cttacgaacc atgattattg gcattccgaa
     4201 tgctggtaaa tctaccttga tgaatcgctt ggctggtaag aaaattgctg tggttggtaa
     4261 taaacctggt gtgaccaaag ggcaacaatg gttgaagtcc aataaggaat tggaaattct
     4321 agatacccct ggtattttat ggccaaaatt tgaggacgaa ttggttggct taaaattagc
     4381 tttaacaggt gctatcaagg accaattact accaatggat gaggtcacta tttttggttt
     4441 gaattacttt aaaacacatt atcctagtcg ccttactaag cgttttaaga atattcctct
     4501 tgaggaagaa gctcctgaaa tcattatgac cttaacacgt cagcttggct ttaaagatga
     4561 ttacgaccgt ttctacagtt tattcgttaa ggaagttcgt gatggtaaat taggtcaata
     4621 caccttagat caggtgggag atatggatgc cgactagtat taaagctatt aaagaaagct
     4681 tagaggccgt tactagcctc ttggaccccc tctttcaaga attggcaacc gacactaggt
     4741 caggcgtcca aaaagcgcta aaaagtcgac aaaaggctat tcaggccgat ttagcagagg
     4801 aagaacgatt agaagccatg ctttcttatg aaaaagcgct ttataaagaa ggctaccaag
     4861 ccattgcagg tattgatgag gtgggacgtg gccccctagc aggtcccgtt gtcgcagcat
     4921 gtgtcatctt acctcaacat tgcaaaatta aaggtctgaa tgattctaaa aaaatcccta
     4981 aatctaagca tgagaccatt tatcaggcag tgaaagaaaa ggctttggct atcggtatcg
     5041 gtattattga caatcagctg attgatgagg tcaacattta tgaagcaacc aaactagcta
     5101 tgctagaagc cattaaacag ttggagggcc aactcacaca accagattat ctcttgattg
     5161 atgccatgac attggatatt gctatttcgc agcagtctat tcttaaaggc gatgccaatt
     5221 ccttgtctat tgcagcagca tcaattgtag ctaaggtcac cagagatcag atgatggcta
     5281 actatgatcg catttttcct ggttatggct ttgctaaaaa tgcaggctat ggcaccaaag
     5341 aacatttaca gggattaaaa gcttacggca taacgcctat ccatcgtaaa agttttgaac
     5401 ctgttaaatc catgtgctgc gattcaacta atccttaaaa agttctgttt ttagcagaat
     5461 ttttttcttt tttacgaata aatgaagtaa ggaggtaact tagtgaatca ttttgaactt
     5521 tataagctaa agaaagctgg actgactaat aaaaacattc tcaatattct tgactaccaa
     5581 aaacaccagg aaaaatcgtt gtcacttcga gatatggccg ttgtttctgg ttgtaagcat
     5641 ccgtctcact ttatagaagc ctataagcag ttagatattc aaaaattaaa aatggaattt
     5701 aaacaatttc ctagtatttc tatcttagat aagcattacc caatggcatt gaaagaaata
     5761 tacaatccac ctgtcctctt gttttttcag ggaaatttag accttcttga gaaacctaaa
     5821 ttagccattg tcggctccag acgctcaagc gataccggag taaggtctgt ccgtaaaatt
     5881 cttaaagaac tcgggaaccg ttttgtgatt gttagcggac ttgctcgagg tatcgacact
     5941 agtgctcatt tagcctgcct taaaaatggg ggacaaacca tcgctattat tggaacaggg
     6001 ttggatcgct tttatcctaa agaaaatagg gagttgcaaa ctttcttagg gaaaaatcat
     6061 cttgtgctaa cagaatacgg tccaagagaa gaagctttat cttatcactt tccagaacgg
     6121 aatcgtatta tcgcaggcct tagccgaggt attcttgtcg ttgaagcaaa aaatcgttca
     6181 ggttccttga ttacttgtca aattgggata gaagaaggcc gagacatttt tgctgtccca
     6241 ggaaacattt tggacgggaa atccgaaggt tgccttcagt taattaaaga gggagcaaca
     6301 tgcgtcacat cgggcatgga tatcctttca gagtactaaa aaagttaaag tttcttccta
     6361 tatagcattt ttttattgac agtttcttaa aaatgggata ttatgctata agctttaaac
     6421 aaactgttat aggaagtgtg tcgaattggg aacaaaaact acaactaagc caaaaacggg
     6481 tactaaaaag tccaccacta aaaagaaatc aacagcgaaa aaaaatctcg ttattgttga
     6541 atcacctgcc aaagctaaga ctattgaaaa atatcttgga cgcagttata aagttgttgc
     6601 ttcggtagga catattcgtg acttaaaaaa atcgtctatg tctattgatt ttgataataa
     6661 ttatgagcca caatacatta atatccgtgg taagggaccc cttatcaatt ctttaaaaaa
     6721 agaagccaaa gctgctaaaa aagtttactt ggcaagtgac ccggaccgtg agggagaggc
     6781 tatttcttgg catttgtcac atattctagg actcgatcct gaagataaaa accgagtggt
     6841 tttcaatgaa attaccaaag atgcggtgaa aaatgctttt gtggaacctc gtcaaattga
     6901 catgaactta gtggattctc aacaagcccg tcgcgtcttg gaccgtattg taggttactc
     6961 catctcacct attctttgga aaaaggtcaa aaaaggcctt tcagcaggac gtgtccagtc
     7021 ggttgcttta aaactcatca ttgaccgtga aaatgaaatc aaagcctttg ttccagaaga
     7081 atactggtct attgatggcc tcttcaaaaa aggaaccaag aagtttcaag caagttttta
     7141 cggtcttgat ggcaagaaga tgaaactttc caacaatgat gacgttaaag cagttcttgc
     7201 taaattaaaa ggtgatgatt tcttggttag taaggttgag aaaaaagagc gccgtcgaaa
     7261 tgccccatta ccttatacga cctcttctct acaacaagat gctgctaata aaatcaattt
     7321 cagaacgcgt aaaaccatga tggtagccca acaactgtat gaggggattc atttaggaga
     7381 aaacggaact caaggtttaa ttacctatat gcgtactgat tctacacgga ttagtcctgt
     7441 agcgcaaaat gatgctgctc aatttattat caatcgcttt ggagctaatt attcaaaaca
     7501 tggtaatcgt gtcaaaaata ccagtggtgc ccaagatgct cacgaggcga ttcgtccatc
     7561 tagtgttaat catacgccag actctattgc caaatacctt aacaaggatc agttaaaact
     7621 ttatactctg atttggaatc gttttgtggc tagccaaatg acagcagctg tttttgatac
     7681 cgtaaaggtg aatttggagc aaaatggcgt gctttttgtt gccaatggaa gccaaatgaa
     7741 atttgacggt tatatggctg tttataatga ctcagataaa aacaaaatgt tacctaaaat
     7801 ggaagaagga gaaaacgtta aaaaggtatc aacttctcca gaacagcact tcacgcaacc
     7861 tccggctcgc tactccgaag caactctgat taaaacttta gaagaaaatg gggtcggtcg
     7921 accatcaact tatgccccaa ccttagaagt gattcaacgc aggtactatg ttaaattatc
     7981 tgctaagcgc tttgagccaa ctgagcttgg ggaaattgtc aacaagctta ttgtcgaatt
     8041 tttcccagat attgttgatg ttgcctttac tgccgagatg gaaggtaagc tagatcaagt
     8101 tgaaatcggt gaagaagaat ggcaacatgt catcgatcaa ttctatcaac cctttgtcaa
     8161 agaattgaat aaggctgagt ctgaaattga aaagattcaa atcaaagatg agccagctgg
     8221 ttttgactgt gatgtttgtg gccacccaat ggtcattaag ttaggacgtt ttgggaaatt
     8281 ttacgcgtgc agcaacttcc ctgagtgtcg taatacaaaa gccatcacta aagaaatcgg
     8341 tgttacctgt cccatttgtc ataagggaca agtcattgaa cgaaaaacta agcgcaatcg
     8401 gatcttttat ggttgtgatc gctacccaga atgtgacttc acttcttggg atttaccagt
     8461 tggacgtgac tgtcctaagt ctggtgacta tcttattgag aaaaaagttc gtggtggcaa
     8521 acaagtaatg tgtagcaatg agacctgtga ttacaaggaa gaaaaaatta aatgaggatt
     8581 acaaaagagg ctacacatag cctcttttgc ttttttcccc tttctgttat aataagtcag
     8641 gtaactacat tagaaagatt tgtgggtctg tcatctaaga gatgtcattc ccgaagaggt
     8701 attagtgact tgtctcaatc aactgcaact tatattaatg ttattggagc tggactagct
     8761 ggttctgaag ctgcctatca gattgctaag cgcggtatcc ccgttaaatt gtatgaaatg
     8821 cgtggtgtca aagcaacacc gcaacataaa accactaatt ttgccgaatt ggtctgttcc
     8881 aactcatttc gtggtgatag cttaaccaat gcagtcggtc ttctcaaaga agaaatgcgg
     8941 cgattagact ccattatcat gcgtaatggt gaagctaatc gtgtacctgc tgggggagca
     9001 atggctgttg accgtgaggg gtatgcagag agtgtcactg cagagttgga aaatcatcct
     9061 ctcattgagg tcattcgtga tgaaatcaca gaaatccctg acgatgccat tacggttatc
     9121 gcgacgggtc cattgacttc agatgccttg gcagaaaaaa ttcacgcgct aaatggtggc
     9181 gacggattct atttttacga tgcagcagcg cctatcattg ataaatctac cattgatatg
     9241 agcaaggttt accttaaatc tcgctacgat aaaggcgaag ctgcttacct caactgccct
     9301 atgaccaagg aagaattcat ggctttccat gatgcactaa caaacgcaga agaagcaccg
     9361 ctgaatgcct ttgaaaaaga aaagtatttt gaaggctgta tgccgattga agttatggct
     9421 aaacgtggca ttaaaaccat gctttatgga cctatgaaac ccgttggatt ggaatatcca
     9481 gatgactata caggtcctcg cgatggagaa tttaaaacgc catatgccgt cgtgcaattg
     9541 cgtcaagata atgcagctgg aagcctttat aatatcgttg gtttccaaac ccatctcaaa
     9601 tggggtgagc aaaaacgcgt tttccaaatg attccagggc ttgaaaatgc tgagtttgtc
     9661 cgctacggcg tcatgcatcg caattcctat atggattcac caaatctttt aacggaaacc
     9721 ttccaatctc ggagcaatcc aaaccttttc tttgcaggtc agatgactgg agttgaaggt
     9781 tatgtcgaat cagctgcttc aggtttagta gcaggaatca atgctgctcg tttgttcaaa
     9841 agagaagaag cacttatttt tcctcagaca acagctattg ggagcttgcc tcattatgtg
     9901 actcatgccg acagtaagca tttccaacca atgaacgtca actttggcat catcaaagag
     9961 ttagaaggcc cacgcatttg tgacaaaaaa gaacgttatg aagctattgc tagtcgtgct
    10021 ttggcagatt tagacacctg cttagcgtcg ctttaacact aaaaaagagt tccttttcag
    10081 ttgagttgct gaagaggact tttttacttg ctgatttgag cgctagctat gcaaaagaat
    10141 gcacaaaaaa tacatgaata gactatggtc actagaagca atattatata atgaatagta
    10201 ctcattagtt gattcagttt ggaggtttta gcatgcagca gcaagtcgca ataacagaaa
    10261 cagttttacg ggacggtcat caaagtttga tggcaacgcg tttatctatt gaagatatgc
    10321 ttcctgtcct taccatctta gacaagattg gttattattc cctagagtgt tggggaggag
    10381 caacctttga tgcctgtatt cgttttttga acgaagaccc ttgggaaagg ctgcgcacgt
    10441 taaaaaaagg cttacctaat acccgtttac aaatgttatt aagaggccaa aaccttttag
    10501 gctaccgtca ttatgcagat gacatcgttg acaaattcat tagtttatca gctcaaaatg
    10561 ggattgatgt tttccgcatt tttgatgccc taaatgaccc acgaaatatc cagcaagcct
    10621 taagagctgt gaaaaagacg ggtaaagagg ctcaactgtg tattgcctat acaactagcc
    10681 cagtgcacac gcttaactat tacctttctt tagtgaaaga attggttgag atgggagctg
    10741 attctatctg catcaaagat atggctggta ttctaactcc caaagcggct aaagagttgg
    10801 tatctggtat caaagccatg actaacttac ctcttattgt gcatacccat gcaactagtg
    10861 gcatttctca gatgacctat ctagcagcag tagaagctgg tgctgataga attgatacgg
    10921 ctttgtcacc ttttagcgaa ggcacttcac aacctgctac agaatccatg tatttagcct
    10981 taaaagaagc aggttatgat atcacattag atgaaacact actggaacag gctgctaatc
    11041 accttcgaca agcccgtcaa aagcacttag cagatggcat tctggatccc agtcttctct
    11101 ttccagaccc aaggacacta caataccaag ttcctggagg catgttatct aatatgctat
    11161 ctcagctgaa acaagccaat gccgaatcaa aattagaaga ggttttagca gaagttcctc
    11221 gggtaagaaa agacttgggt tatcctccct tagtaacacc gcttagccaa atggtcggga
    11281 ctcaagctgc tatgaatgtg attttaggaa aaccttacca gatggtgtct aaggaaatta
    11341 aacaatactt ggcaggcgac tatggcaaaa caccagcacc agtcaacgaa gacttaaaac
    11401 gaagtcaaat tggctcagct cctgtcacca caaatcgtcc tgcagatcaa ctaagtcctg
    11461 aattcgaggt gttaaaagca gaagtagcag atttagccca aacggacgaa gatgtgctga
    11521 cttatgccct cttcccaagc gtagcaaaac cgtttttaac aaccaaatac caaactgatg
    11581 acgtcattaa agtgactgcc tttatcaaag cataataggc tatcttaatc agatagaaac
    11641 aaaaatatgg agatcaaatg acctattcct ttattgatat cttacaagtt accttagtat
    11701 ccttgttctt agtgttaacc tgtttaacag ggattatggg attaatgatg ctaagtggta
    11761 aattattgtc acaagaaaaa aaaactctct ctcaacaagc ttccagcatt cctcaagagc
    11821 aagaagctga caagttgagt ggagaagctc tcgaaactct tttagccaaa gacgaattgg
    11881 ctagaattgc tgttatgact agtcttgctt atgctagcca agaagagtca ggaaaacggt
    11941 ttgaagttat tgccgtggaa aggaaatcct aatgaaaaga tatgaagtga ctgtcaatgg
    12001 acaggtttat gaagtgagtt tacgtgaact agctgatgga gaaactgttg aagttagcca
    12061 gccagcagca cccgctactg agaaagaaat gaatgccaac gctgctggcg gtggcattca
    12121 ggtaaaggct ccaatgtctg gaacagtctt gtctatcttt gctacagaag gaaaagctgt
    12181 taaaaaagga gaagctgttc tggtcttaga ggccatgaaa atggagaatg aaattctagc
    12241 acctgcagat ggtctggttt caaaaattca tgttgtggct aaccaaacgg tcgagtctga
    12301 acaagttttg atttcattct aggaggaaac catgctagac gtactcaatc aaatggttca
    12361 atcgtcagga ttggctcatc taactgttaa caatcttatc atgatttgct tggcctgttt
    12421 ctttttatac cttggtatca aaaaggaata tgagccttac cttatggtac caatcgcctt
    12481 tgggatttta ctcgttaatt tgcctatggc gggattgatg gaccaccctg ccaatggtaa
    12541 tcctggtggc cttctttatt acctatataa gggaactagc ctagggattt acccaccttt
    12601 aatttttctt tgtttggggg catcaactga ctttggtccc ttgattgcca atcctaaaac
    12661 cattttacta ggaggcgcag cacaagttgg gattttctta gcctttttcc ttgctattat
    12721 gttaggcatg acacctcaag aagcggcttc tgtcgggatt attggtggtg ccgatggacc
    12781 aacagctatt tatgtgacga caaagttggc gcctgattta ctctctacta tcgccctagc
    12841 agcttattct tacatggctc tggtacctat tattcaacct cccatcatta aactcttgac
    12901 taccaaggcg gaacgccaag tgaaaatgac tcaagcaaga actgtgtcac aaaaagaaaa
    12961 aatcattttc ccgattatgg taacaatctt tgtcagcctt ttggttccaa gtgctacaac
    13021 cttggttggc tgtttgatgc tgggaaatct ggtcagagaa attaaaattg ttcctaaaat
    13081 tgtagagaat ctccaacaag tggttatgtt ttgcattact atcattttag gattaaccgt
    13141 tggtgctaag gccaatggag atctcttttt atcagccaca accttgaaaa ttattgccct
    13201 tgggctaatc gcctttgctg ctgggacagc agggggtgtc ttgatgggga aggtcatgta
    13261 ctatttatct ggtaacaaag tgaaccctat gataggagca gcaggtgttt cagctgttcc
    13321 gatggcagcg cgagtggtcc aaaaggtcgg acaagaagaa gatccaagta atttcttact
    13381 catgcacgcc atggggccca atgtagctgg cgttattggc tcagccattg cctcaggtgc
    13441 cttgctggcc ttctttggct aattgtgaaa aaggattagt aaattaatct taataaatca
    13501 ttatcaggag ttggaagcaa tctagctcct tttttagtag aaagctcgag tgataaacta
    13561 ttccaaaata attataaaaa aagactgtcc tgattgtacg gactatatca attgactttt
    13621 atagtctagc tgaaatagca gtgcaaaact aagacactcg ttttaaagta gtttttctaa
    13681 aaaagcaaaa taaaaggtca gagccaataa atctgccgcg cccccagggc ttaaatgctg
    13741 attaatgagg cattgattgt aggaggacaa agccaatctt agatcagttg ttgataaatc
    13801 ttgttgcagg agtagtcgca tatctgcctt aacgcctttc catgcttcaa tccctccacg
    13861 atgaatcaga tttccatctt caacaataga catcaaataa acaagaagac gaagctgact
    13921 ggtttcgggg tcattttgac ttatcatctg acgaaagtag ggcaaggcat ggtctgttaa
    13981 ggtcgtgaat ccctcgcttg cctcaccccg aggtcctttg atgccataag ttacaaagag
    14041 ttgctcccca taagtgaact cttttttagt gttcaaatga ccaaggtctg tttgaatcaa
    14101 atgtgccgtc ataggtttta ctaaacgaca gatagctaga gtatcttcct tgctaaaacg
    14161 ccctaaatca gtcattaagt gaggtgttct tgctagatag gccccagttg caccaagaag
    14221 taaagccatg gaaaaattca agcctttatg agtgttaatt ccctgagtag cacaaaacat
    14281 ggtttcctcg gccttttgac ctagttgtct aagacggtta aacagaagaa gtggctcttc
    14341 ttttgcataa gcaaaacctg tttcgatata agcctgaaaa aaaggagaga gtgctatcat
    14401 actgtcgata aaggtcataa aggacatgtc atcatgggca ccgttatcaa atcgatcaac
    14461 taaaccaggt tttggagata gtgagacttc ataaagcaaa gcttttaagg ccagttgact
    14521 aatacttgtt agaactgcct tagtcatttt gctcaggcct catttctttt aagataaatt
    14581 caagtgagct attcaagtgt tcatgtgtaa tcaacgtaat ttgctcatga tctttgttct
    14641 tcatacctcg gtaaatcatc cagtgttcag atagagctcg tttacggcgt tcaactgaag
    14701 aaatcgaaat ttttctaaag tagaccaaat aagcttgcaa ttctgtcaca atttctttta
    14761 agcggaccat ttggctatag ctgtaaatca aattgttaaa ggcattaaaa ttatccaaaa
    14821 tacgattggt gtcatcctct gcgataaagg tttcacagtc ttccaacaag ttatgcatga
    14881 ctttaaaatc ttcttctgtc attaaatgca tcgcttgcac cgttgcgaga gtctctagag
    14941 cttttcgaat ttcaaaaatt tcacaggcat ccttgatact aactcctttg acaataatgc
    15001 cttttttagg aatgtgctct acaaggtgtt cttcagacaa taatcccaaa gcgtagcgaa
    15061 taggtgtcct gctaatatta agcgcaatgg aaaactcttt ttcattaatg cggcttccaa
    15121 caggaatttg tcgcaaaata atggtctttt taagagcgtt ataaaaggct attttcaaag
    15181 ggatatttct tgataggtca agattttgtt taacggcttc gataatagga ttcatgtcat
    15241 ctccttaatg ctagtgtcct cactttatta tacttaaatt tgtgaaacat tccaatagga
    15301 ctagatgagt tctgaaaaat taaagccatg ctcacaaaag gacatgactt taatcatctc
    15361 ataaggaata aagtagtagt gttatcgttg gtttattgtg gaatgtaaag tggcatttgc
    15421 cccatggcaa taatggttac cacaaagata acaaagatga taagggcata tttagcagcc
    15481 tctttttgcc attcccccat atcaagacct gtcaagcgaa gaaggaggta aatgaaggca
    15541 actaatggac taagtaagtg gaaggcttgt cccatgaggg aagcaagtgc catagccatg
    15601 ttactgaaac catattcagc accagcttct gcaagaaccg gcaagatacc atagtaaaaa
    15661 ccatcattgg agataaagaa ggtaccaggt gcagaaacta aggcaataac gagaccccag
    15721 aaacctgcca gttgttttgg aataatggtt gcaaaacttt gtgcaagagc gctagccata
    15781 ccagaacctt ggaaaagacc cataaagata ccagcagcaa agacgagaat aaccacttga
    15841 accgcatcac cagcattgtc accaatgcgt tttgattgat ctttaagcac ggggtaattg
    15901 accatcaagg cgatacaagt tcccaccgca aaaagaagaa gcggtgccat agcaatagat
    15961 ttgttgaaag agccagcaac taaccaagtg attaatccaa tggttaggat agcattgaaa
    16021 acaaagtttt taggacgacg aataaaaagg gtatctgggt cagtaatgtc tgtgagttga
    16081 cgcatgtctt cttcagacaa gtcaataaca ccaagtcttg cacgttcttt acgccccatg
    16141 cttggagcaa cccaacaaat cacataaaga agagataaaa tcatacccgg tgcaagatag
    16201 ccaagaattt caggaccgac accaagaaca gacatcgcac gagcagtagg gccaccccat
    16261 ggcagtaagt tcataatagt attttgaaga ataatcaaga cacctaggtt catgattttc
    16321 atgtccaatt ttttatagat aggtaagaaa gcagagcaac aaattaaagt agtggttgtt
    16381 ccatcaccat taagagatac tgcggcagca acgacagctg ttgcgataag caccttcatt
    16441 ggatcacctt tagcaaagcg aatcatcttt tcagtaatcg gatcaaacaa tcctgcatct
    16501 aacatgacag agaagaacaa aatggcaaat agcaacatga tacctgtttt agcagtattg
    16561 ttgataccat acataaccat tggtccgata gctgttaggt ctttagcaat tccaccgtca
    16621 ccaacaaagg caacaaattt ggcatctgca ttgaagtcag ctgaaccagt cagtataaca
    16681 gcaatcgtca tgattaatgg aatcatgacc aaagcagtaa aaggggtcat ttttttcttc
    16741 attaccacgt acataaagac aataatcatg gcataagcca gcattgttaa taacattatt
    16801 attatctcct ttttcaagtt atgatttcag tatagatgaa agcgcttata aaataaatac
    16861 ttctttgtgc agaaagacac aaaaaaaaca atttgaaaat taattttgaa aaccattttt
    16921 attacatcag atgactttaa attttctata ataa
//
LOCUS       DAUNLR010000037        16334 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUNLR010000037 DAUNLR010000000
VERSION     DAUNLR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16334
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.037"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            79..729
                     /locus_tag="VLL59_001250"
     CDS             79..729
                     /locus_tag="VLL59_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HER6509373.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGGKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            732..1400
                     /locus_tag="VLL59_001251"
     CDS             732..1400
                     /locus_tag="VLL59_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6509374.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVFIAGDKDTSYC
                     LLEK"
     gene            1409..2641
                     /locus_tag="VLL59_001252"
     CDS             1409..2641
                     /locus_tag="VLL59_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HER6509375.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSMMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            2935..3813
                     /gene="mvk"
                     /locus_tag="VLL59_001253"
     CDS             2935..3813
                     /gene="mvk"
                     /locus_tag="VLL59_001253"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HER6509376.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            3795..4739
                     /gene="mvaD"
                     /locus_tag="VLL59_001254"
     CDS             3795..4739
                     /gene="mvaD"
                     /locus_tag="VLL59_001254"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HER6509377.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSISFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDQWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            4732..5745
                     /locus_tag="VLL59_001255"
     CDS             4732..5745
                     /locus_tag="VLL59_001255"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HER6509378.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQDARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            5732..6721
                     /locus_tag="VLL59_001256"
     CDS             5732..6721
                     /locus_tag="VLL59_001256"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HER6509379.1"
                     /translation="MTNRKDDHIKYALKYQSLYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(6951..8228)
                     /locus_tag="VLL59_001257"
     CDS             complement(6951..8228)
                     /locus_tag="VLL59_001257"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HER6509380.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(8215..9390)
                     /locus_tag="VLL59_001258"
     CDS             complement(8215..9390)
                     /locus_tag="VLL59_001258"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HER6509381.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLTEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            9599..10438
                     /locus_tag="VLL59_001259"
     CDS             9599..10438
                     /locus_tag="VLL59_001259"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HER6509382.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            10518..11015
                     /locus_tag="VLL59_001260"
     CDS             10518..11015
                     /locus_tag="VLL59_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HER6509383.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            11035..11205
                     /locus_tag="VLL59_001261"
     CDS             11035..11205
                     /locus_tag="VLL59_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509384.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            11335..12564
                     /gene="clpX"
                     /locus_tag="VLL59_001262"
     CDS             11335..12564
                     /gene="clpX"
                     /locus_tag="VLL59_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HER6509385.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            12574..13173
                     /locus_tag="VLL59_001263"
     CDS             12574..13173
                     /locus_tag="VLL59_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HER6509386.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            13321..14064
                     /locus_tag="VLL59_001264"
     CDS             13321..14064
                     /locus_tag="VLL59_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509387.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKVLKKSPSSV"
     gene            complement(14122..16221)
                     /locus_tag="VLL59_001265"
     CDS             complement(14122..16221)
                     /locus_tag="VLL59_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HER6509388.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATTSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEGTIQNLIQEVKEAGNIILFFDEIHQIVGAGTTSSDPGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMCIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSGFNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQKDQ"
BASE COUNT         5134 a         2850 c         3294 g         5056 t
ORIGIN      
        1 ttatatagtt agaaataaag ataaccgatc attgcagaga tttaagcatt tgttgagaaa
       61 atttgttata ataagcgtat gaaagaaaga ctagaacatt attctaccag ctctatatat
      121 agcggatttg aagtgtactt gccgttggta ctacagacaa taacagatgt gattattgct
      181 gagaatatca aaagcaaaaa agaaacgggg tttaaactat acgaacactt tacatcccgt
      241 attaaatcgg aagcttcgat gattgaaaaa tgtcaacgca aacagcttcc tctaacaagc
      301 aaatctgcgt taaaaatcat taaagatagt atcggtattc gcattatttg tggttttatt
      361 gatgatattt atcggatggt agacttgctc aaaagcattc ctggtatgtc agttaacact
      421 gaaaaagatt atattttaaa tgccaagcct aatggctata gatcatatca tctcattttg
      481 gaattagaaa cacattttcc agatatttta gggggaaaaa aaggatgtta ttttatagaa
      541 gtgcagttgc gaaccattgc tcaagactct tgggctagct tggaacatca aatgaagtac
      601 aaacatcaag ttgctaatgc agaaatgatt acaagagagt taaagcgttg tgcagacgag
      661 ttggcatctt gtgatgttac catgcaaacc attcgtcaat tgattcaaga aacgacggag
      721 gaagagtaac catgaaaatt ttgttagctg aagacgaatg gcagatgtct aatgttttga
      781 caactgccat gactcatcaa ggttatgacg ttgatgtggt ttttaacggt caagaggcaa
      841 ttgataaagc taaagacaat gcatatgata ttatgatttt agatatcatg atgccgatta
      901 agtctggcat tgaggcttta aaggagattc gcgcttcagg aaattgctca catattatta
      961 tgctgacggc tatggcagaa attaatgacc gtgttactgg actagatgcg ggagctgatg
     1021 attatctgac taaaccgttc tcattaaaag aacttttagc tagattaagg tcgatggaaa
     1081 gacgagtaga aagttttact cctcaggtat tacaatttgc tggtgtcaca ttaaatatta
     1141 atgagcaaga attgagtgcc ggtaatgcta tacgattagc ttctaaagaa ggtaaattaa
     1201 tggccttttt aatgttaaat caaggaaagt acttggatac taaaacactt taccaacatg
     1261 tttggtcaga ccaagaagat tatgatactt ctattgtttg ggtttatatt tcttatcttc
     1321 gtcaaaaatt attagctatt caagcaaatg tttttattgc aggtgataaa gatactagct
     1381 attgtttatt agaaaaatag gaggtgacat gtttaatcgt atccgtattc gttttatcat
     1441 gattgcttct attgccattt ttattatttt aagttcaatt gttggtatta ttaacacggc
     1501 acgctgttac caaagtcaac aagaaattaa ccgtatttta catttaattt cctcaaataa
     1561 aggtaaatta cctggcacta cggaaagctc taaacgactt ggaacgaaac tgtctgaaga
     1621 tagcctaagc cagtttcggt attatagtgt catttttaat gctaatggac atctactttc
     1681 ttctaatact gctaatattt cagctttaga tagagaagaa gcccaatatt ttgctagact
     1741 ttttgctaag tctggggaag aaaaaggcag ttaccgtcac caagatagtg tttattcgta
     1801 cttgattact cagctgccaa atgaagaaaa actggttgtt attttagata ctacctttta
     1861 ttttcgtagt gtaggagatt tattagccgt ttcaatgatg ttggcctttg gaggatttat
     1921 cttttttgtt gttttagtga gtcttttttc cggtatggtc atcaaacctt ttgttcaaaa
     1981 ttatgagaag cagcgccgct ttattactaa tgcaggccac gagttaaaaa caccactagc
     2041 cattatctca gccaataatg aattggtcga attaatgact ggagaatcag aatggaccaa
     2101 gagtacaagt gatcaggtga agcgattgac aggcttgatt aatcaaatga ttactttggc
     2161 tcgtttggag gaacagccag atgtggtatt acatatggta gacttttcag ctattgctca
     2221 agatgcagct gaagatttta agagtctggt tttgaaagat ggtaaacgtt ttgatttgac
     2281 gattcagccg aatattatga ttaaagcgga ggaaaagtca ttatttgaac ttgtgacaat
     2341 tttagttgat aatgccaata aatattgtga tcctaaaggc ttggtcaagg tatctttaac
     2401 cactattgga agaagacgaa aacgagcgaa attagaagtt tctaatacct atttggaagg
     2461 aaaatccatt gattacagcc gcttttttga acgcttttat cgcgaagacg aatcccataa
     2521 tagcaaagaa aaaggttatg gaattggttt atctatggca gaaagtatgg ttaagttatt
     2581 taaaggaacg ataactgtaa attataaaaa cgatgctatt gtttttacag tggtgatttg
     2641 acttaaacat ttttcagtac ctttagctag taataatgtc taggtaaagg taataaacga
     2701 tgcttaacca gcccatgagg ctggttttta acgtttaatt tagtagaaga gtgattaaag
     2761 aaggtagttt gaaataagaa aatttttgtt atgatcctaa aaagagtaga tagtctttat
     2821 tgttaatttc ggtgaagaaa tgattttaaa aagatatatc atcgcatttt ctaatcattt
     2881 agtgtaaaat agtaaggtaa aagtttagaa gaattagtaa tgaaaagata aaaaatgaac
     2941 gaaaacattg gatatggtaa ggcacacagt aagatcattt tgataggtga gcatgctgtt
     3001 gtgtatggct acccagctat tgctttgcct ttaacagata ttgaggtggt ttgtcatatt
     3061 tttccagctg ataagccatt ggtctttgat ttttatgata ctctatcaac agccatttat
     3121 gctgccttgg attatttgca gcgactacaa gaaccaattg cttatgagat tgtttcacaa
     3181 gtgccacaaa agcgtggtat ggggtcttcg gcagccgttt ctattgcagc tattagagcc
     3241 gttttttctt attgtcaaga acccctctcg gatgatttgt tggaaatttt agtcaacaag
     3301 gcagaaatta ttgcccacac caatcctagt ggtttagatg ccaagacatg ccttagtgac
     3361 catgccatta agtttatccg aaacattggc tttgaaacta tcgaaatcgc cttaaatggt
     3421 tatcttatca ttgcagatac agggattcac ggtcatacac gtgaggccgt caataaggta
     3481 gcacagtttg aggaaacgaa tttgccctat ctggctaaac taggagcttt gacacaagcc
     3541 cttgaaagag cgattaacca aaaaaataag gtggctatcg gtcagctcat gacacaagcg
     3601 cactctgctt taaaggccat tggcgttagc atcagtaaag ctgaccaact tgtggaggct
     3661 gccctaagag caggtgcttt aggcgctaag atgacaggcg gtggcttggg tggctgtatg
     3721 attgccctag cagataccaa agacatggcc gaaaaaatca gtcacagatt aaaagaagaa
     3781 ggagccgtaa acacgtggat ccaaatgtta taaccgtaac atcctatgct aacattgcta
     3841 ttatcaaata ttggggaaaa gagaatcaag ctaagatgat tccttcgacc tctagcattt
     3901 ctttgacttt ggaaaacatg ttcaccacaa ccagcatttc cttcttacca gatactgcaa
     3961 ccagtgatca gttttacatt aacggtgtct tgcaaaatga cgaagaacat accaaaattt
     4021 ctgctatcat tgaccaattt cgccaacctg gtcaggcttt tgtaaagatg gaaactcaaa
     4081 ataatatgcc aacagctgca ggtttatcat caagttccag tggcttatca gccttggtta
     4141 aagcctgtga ccaattattt gacacccagc tagatcagaa agctttagct caaaaggcta
     4201 agttcgcctc aggatcatct tctcgttctt tttttggccc agtcgctgct tgggacaaag
     4261 atagtggtgc tatttacaag gttgagactg acttgaaaat ggccatgatt atgctggtct
     4321 taaatgctgc gaaaaagcca atttctagcc gagagggcat gaagttatgc cgcgatacct
     4381 caactacatt tgatcaatgg gtagaacaat cggcaatcga ttaccaacat atgcttacct
     4441 atctcaaaac taataatttt gagaaagttg gtcagttgac agaagctaat gccttggcca
     4501 tgcatgccac gacaaagaca gccaatcctc ctttttctta cctaacaaaa gagtcttacc
     4561 aggctatgga ggctgtgaaa gaactgcgtc aagaaggttt tgcttgttat tttaccatgg
     4621 acgcaggtcc aaatgtgaag gtcctatgtt tagaaaaaga cttggctcaa ctggcagaac
     4681 gacttggcaa gaactaccgt attatcgttt caaaaacaaa ggatttacca gatgtctaat
     4741 tattgtgtgc aaacaggtgg gaaactatac ctcacaggcg aatatgctat cttaacacca
     4801 ggacaaaaag ccttaattca ctttattcca ctgatgatga cagcagaaat tagcccagca
     4861 gcccatattc aattagcttc agatatgttt gcccataaag caggcatgac gcccgatgcc
     4921 tcttatgcac tgattcaagc aacggttaaa acctttgctg actatctagg acagtcgatt
     4981 gaccaactgg agccattttc cctaatcata acaggaaaaa tggagcgcga tggcaaaaaa
     5041 tttggcattg gttcaagtgg tagcgtcacc ctcttaacct taaaggcctt atcggcctat
     5101 tatcagatca ctttaacccc agagttactc tttaaactag cggcttatac cttgcttaag
     5161 caaggagata atgggtctat gggggatatt gcctgtatcg cttaccagac tttagtcgcc
     5221 tatacctcct ttgaccgaga acaggtcagt aactggctgc agaccatgcc cttaaaaaaa
     5281 cttctcgtca aagattgggg ttaccatatc caagtcattc aaccagccct gccttgtgac
     5341 tttttggttg gctggactaa aatacctgct atttcaaggc agatgattca acaagtgaca
     5401 gcgagcatta ccccagcttt cttaagaaca agttaccagc taacgcaatc agctatggta
     5461 gctttgcaag aaggtcataa ggaagaactc aagaaaagtt tagcaggagc aagtcatctc
     5521 ctaaaagagc ttcatccagc tatctaccat cctaagctag taaccttggt agctgcttgt
     5581 cagaagcaag atgctgttgc taaatcttca ggttctggtg gtggagattg tggcatcgcg
     5641 cttgccttta atcaggatgc tagagatacc cttatttcca aatggcaaga agctgatatc
     5701 gcattacttt atcaagaaag gtggggagag aatgaccaac cgtaaagatg atcacatcaa
     5761 atatgccctc aagtaccaat cgctttataa tgcttttgat gacatagaac tcatacatca
     5821 ttccttacct agctatgatt tgtctgatat tgatctcagt actcattttg ccgggcaaga
     5881 cttcgacttt cccttttaca tcaatgccat gacaggagga agtcaaaaag gcaaagctgt
     5941 caatgaaaaa ttggccaaag tagcagcagc aacagggatt gtcatggtga cagggtctta
     6001 tagcgctgct ttaaaaaatc ctaacgacga ttcctatcgt ttacatgagg tggcagataa
     6061 cttgaaacta gccacgaata ttggtctaga taaacctgtg gcgctaggac aacaaacggt
     6121 tcaagaaatg cagcccctct ttttacaggt tcatgtgaat gtgatgcaag agttgctgat
     6181 gccagagggt gagcgcgtct ttcatacctg gaaaaaacac ctcgctgaat acgctagtca
     6241 aataccagtt cctgtcattc tcaaagaagt tggttttggc atggatgtca atagtatcaa
     6301 gctagcacat gacctaggca ttcaaacctt tgatatttca ggaagaggag ggacctcatt
     6361 tgcctatatt gaaaatcaaa gaggaggaga ccgctcttac ttaaacgatt ggggacaaac
     6421 caccgttcag tgcttgctaa atgcacaagg actgatggac caagtggaaa tcttagcttc
     6481 gggtggtgtc agacacccct tggacatgat taaatgtttc gtcctaggag cacgtgcagt
     6541 gggactctca cgcaccgttt tagaattggt cgaaaaatac ccaaccgagc gtgtgattgc
     6601 tatcgttaat ggctggaaag aagaattaaa aatcattatg tgtgctcttg actgtaaaac
     6661 tattaaagaa ttaaagggag tcgactactt actatatgga cgcttgcagc aggtcaatta
     6721 ggcttcatca cctctacaat agtgccacct actacaaaga tgatagagct tttttagaac
     6781 ataatataaa atatttataa atacctcatc aaactcagaa tagagtagat gagtaaatag
     6841 agtatgttat ggagactatt tctaagactt gtatgtatag aaacaaagat taaacaccca
     6901 tgtaaaccaa ttgtttacat gggtgtttgc cttatattag ttgtttaaat ctaagactgt
     6961 cttagctggg ataagtaaaa atgtgctttt tctagattta ttggtttatc agctagtaaa
     7021 gcattaacta aaggagcaat ttcgtcttgg gttgcccccg ccaaaagagc taatgatttc
     7081 gcatgtagtt tcatgtgacc agcttggatg ccagatgagg tcagagcttt tagtgcagca
     7141 aagttttgag ctaaccccac agatgcaatc aattgggcta atgttttggc atcaggttga
     7201 ttaagaagat catgtgcgat agaaacagta gggttaagcc cgatagatcc ccccttacta
     7261 gcaataggca tagggagggt catttggcca agcagaactt gtttatcttg atcaaaatgc
     7321 cactgactaa gtccttgata gctaccattt cttgaggcat aagcatgggc ccctgcttca
     7381 atagcacgcc agtcatttcc tgtggctatt accactgcat caatgccatt aaaaatacct
     7441 ttattatgag tagtagcccg gtaaggatct acttgagcta gtcggctggc tagctctatt
     7501 ttttgagcta actgtaggga ttttgtttta tcgtgatcta aaaggcgcac gggaatctca
     7561 caactagtag taacaagcga ctctgttgcg taattagata aaatcgccat tagacaatgc
     7621 cccttagaca gtcttgttaa atcaggaaca agagcttcca tcatagtatt gaccatattt
     7681 gctcccatag cttcttgggt atcaacagtc agatagaaaa tcaaaaattc tcctttttct
     7741 tccaaatgaa tggttctagc gcctccacct cttttaacaa tggaaggata agctttattt
     7801 gccaatgcaa ttagcttttt tgttttatga aggatggcgg ctttagcgtt atctatttgg
     7861 tcgatatcgt aaagaacaat ttgaccaatc atttgtcggt ttagggtttg agctttaaaa
     7921 ccacctgagc gtttgattag ttttgctgcg aaagatgctg cagcaacaac agaaggttct
     7981 tccgtgacaa aaggcatctg ataagttgaa ccgttgacaa gaaaatcagg agctatgcta
     8041 aagggcaaag ccaatcgtcc taagacattt tcagtcattt gattagctgt ttggataggc
     8101 aaaagaacgt ctgttttgag ttgatttaag ttttcagcat taagtagttt aaatttttcg
     8161 ataagttgga ggcgttcttc gaatgttttc tttgaaaaac cgctccagtt aagattagtt
     8221 tttgtcattg gtatgataga tcctttgatg ctccttgatg gctgttagag caaattttcc
     8281 agttaagtaa atgtcaaaat tggcattacc attatcatct aattggactt gttcgtagaa
     8341 aaggtcttcg tatttagaaa cggaaagacg tgttcgttga tctagtaaag cttgtcgatt
     8401 agtcattaac attttatcgt acccagcaac taactgaccg gaataaaatt cacttacggc
     8461 accggaacca tagctaaaaa aaccaatttt atctccagat tgtaatactt tactattttc
     8521 aagtaaagat aacaatccta gataaagtga gccagtataa atatttccaa tttgtttgct
     8581 ataagtaata gaagcttgaa aggcttctgt tagtttttct ctgtgttcag gaggtactgt
     8641 gttatccata atgttattta gaccttttag ggctaacttg ggaaatggaa tatggaaaca
     8701 aactgcagca aaatcagata actgaaggtt ttctcttttc tgataagctt gccacgtggt
     8761 ttctaagcaa ttgagatatt gcttggtaga gtaaatacca tcaacataag gtgtgaaact
     8821 atagttaggc ctccaaaagt ccataatatc cctagtttga gccacattat ctttatttag
     8881 agcaagaata cgagggttag cagttaccaa aagagcaata ctaccagagc cttgagttga
     8941 ttcgccagga gaccctacac cgtatctagc aatatcacta gcaataacaa ggacacgaga
     9001 atctggctta gaagccacat gcagtttagc atagtctaga gcagcagttg cgctatagca
     9061 ggcttgtttt acttcaaagg aacgtgcaaa aggctggata ccaactaagt gatgtacata
     9121 gatagctgat gcctttgact gatcagtact cgattcagtt gccaaaataa ccatatcaat
     9181 cttagctcga tcttcgtcgg ttaagatttg atctgctgca gaagcagcta aagtaataat
     9241 gtcttcagtg attggtgcca cactaaaaga ctcaatgagt agcccttgac taaattttgc
     9301 tggatccact tggcgtgcaa gcgctaaatc ttccaatttc aagacatatt gactggttgc
     9361 aaaaccaatc ttatcaattc caattgtcat atttgtcctt cttttagtta tttttatagt
     9421 cttacccatt ctatcacatt ttactgcaaa attagactga taaagttatt tgttttatcc
     9481 tttaatagtt aaaatgttca tgaccacatg aagtttttcg aatgtttatt tattctggta
     9541 ttttttggta aaattagtta gaatagtatg aagtatgctt acagaaaggt tattagagat
     9601 gacaaaagct gaccagattt ttaaagctaa tattcaaaaa attataaacg aaggatcatt
     9661 gagtgagcaa gcacgtccta aatataaaga tggtcgaaca gctcattcta agtatattac
     9721 tggggcgttt gctgaatatg atttagctaa aggagagttt cccatcacaa ctttacgacc
     9781 cattccaatt aaatctgcta taaaggaatt attttggata tatcaagatc agtctaacag
     9841 tttagatgtg ctagaagcta aatataatgt tcattattgg aatgaatggg aagttgacca
     9901 gacacgtact attgggcaac gttatggtgc tgtagtcaaa aaacatgata tcatctcaaa
     9961 aatactaaag caattagcag aaaatccttg gaatcgtcgt aatgtcattt ctctctggga
    10021 ctatgaagca tttgaggaga caaaagggtt gttgccatgt gcctttcaaa tcatgtttga
    10081 tgttagacgt gtaggggaag atctttattt agatgctagt ttgacgcaac gttctaatga
    10141 catattagtt gctcatcaca tcaatgccat gcaatacgtt gccttgcaga tgatgattgc
    10201 taaacatttt ggatggaaaa taggtaagtt cttttatttt gttaacaatt tacatattta
    10261 tgacaaccaa tttgatcagg ctcaagaatt actaaaacga cagccagttg ctagtcagcc
    10321 taagcttgtt ttaaatgttc cagatgggac taatttcttt gatattaaac cagatgattt
    10381 tgaattacaa aattatgatc cagtgaagcc tcagttgcac tttgaccttg ctatttaaac
    10441 tttatttaga ttttttgtga gcattttgtt cataaatttg gtaaaataaa tagagtttaa
    10501 aatgaaggaa ataattaatg acaaaggaaa ttattgctat ttgggcagag gatgaagcag
    10561 ggcttattgg tgttgcgggt aagttaccat ggtatttacc aaaagagtta gaacatttta
    10621 aaaagacaac gctacatcaa gcaatcttaa tgggccgtgt gacttttgaa ggaatgaatt
    10681 gcaaaagact tcctcaacgt caaacccttg tcatgacaag aaatagagat tatcaagtag
    10741 atgaggtgtt gacaatgact agtattgaaa aagtcttgga gtggtaccat gcgcaggata
    10801 aaacacttta tatcattggt gggaataagg ttttagaagc gtttaatggt tatttcgatc
    10861 gtatcataaa aacagttatc catcatcgtt ttaaaggaga tacctaccga ccaaatctag
    10921 attttagtca cttcacgcaa gaaagccaaa cgttctatgc tcgagacgct aaaaatcctt
    10981 atgattttac cgttactgct ttaaaacaca aatagtctga ggagatgata agcgatgcaa
    11041 cgtagtattt ttggagtatt tacggctttt ttgtgcgtga tttgtgttct ttgtgccatc
    11101 ccagctttta aaaagaatcg ttatggctta ggaagtctgt tcttattaaa tgcgtttact
    11161 aatctggtta atagtattca cgccttctat ggtacattgt tttgagatgt gacttgcaaa
    11221 gacagcactg gtgaagattt agctatcaag caagaatcac taaaaaccaa tacaacacat
    11281 tgactaatat taaaattcag taaaagataa gagaaagtaa gagaattata agaaatggca
    11341 ggaagtagaa ctaacgatat taaagtatac tgttcatttt gtggtaaaag ccaggatgac
    11401 gttaaaaaaa ttatcgcagg aaataatgtt ttcatctgca atgaatgcgt agctttatca
    11461 caagaaatta taaaagaaga attggctgaa gaagtccttg ccgatttgac agaagttcca
    11521 aaaccaaaag agctccttga tgttttaaat cagtatgtgg ttggtcaaga tcgtgctaaa
    11581 cgtgctttat cagttgctgt gtacaatcat tataagcgtg tctcgtttac agaaagtcgt
    11641 gatgacgatg atgtggattt acaaaagtcc aacattttga tgattggacc aacaggttca
    11701 ggaaaaacct tcttagcaca aactctggct aaaagcctca atgtaccatt tgctattgca
    11761 gatgcaactt ctttgactga agcagggtat gttggagaag atgtggaaaa tattttactc
    11821 aaactgattc aggctgctga ctataatgtc gaacgagcag agcgtggtat tatttatgtt
    11881 gatgaaatag ataagattgc taaaaaaggt gagaacgtat ctatcacacg tgatgtatct
    11941 ggtgaaggtg tacagcaagc ccttcttaaa attattgaag gtacggtagc aagtgttccc
    12001 ccacaaggtg ggcggaagca ccctaatcaa gaaatgatcc aaattgatac aaaaaatatc
    12061 ttgtttattg ttggcggggc ttttgatggc atcgaggaga ttgttaaaca acgtttaggt
    12121 gaaaaagtta ttggttttgg tcaaaacagc cgtaaaattg atgacaatgc ttcttatatg
    12181 caagaaatta tttcagaaga tattcaaaag tttgggctta ttccagaatt tattggccgc
    12241 ttaccagttg tggcagccct tgaacaactt aaaacatcag atttgattcg aatcttaaca
    12301 gagccaagga atgctcttgt caagcaatat caggcccttc tttcctatga tggggttgaa
    12361 ttagaatttg ataaagcagc tcttgaagct atcgcaacta aagcgattga acgtaagaca
    12421 ggagcacgtg gtcttcgttc tattattgaa gaaacaatgc ttgacattat gtttgaaatt
    12481 ccaagccaag aagatgtcac aaaagtgcgt atcaccaagg ctgctgtcga aggcaagtca
    12541 aaacccgttt tagagacagc ttaaggagaa ataatggctg aagaacaagt cttaaatacc
    12601 cataacgcct caattttatt gagtgctgcc aataaatctc attaccccca agatgatttg
    12661 ccagaaattg ccctcgctgg acgttcaaat gttggtaaat caagttttat taataccata
    12721 ttggggcgca aaaatttggc aagaacctca agcaagccag gaaaaaccca actattaaat
    12781 tttttcaata ttgatgacaa gcttagattt gtggatgtcc ctggttatgg ctatgccaag
    12841 gtttctaaaa gtgaacgggc caaatgggga aagatgatcg aagaatactt aaccaccaga
    12901 gataatctgc gtgctgtcgt gagtttggtt gatttacgtc atgccccttc aaaagaagat
    12961 attcagatgt atgacttttt gaagtactat gacattcctg ttattgttgt ggcaaccaaa
    13021 gcagataaga ttcctcgtgg caaatggaac aaacatgagt ctgtggtcaa gaaagctttg
    13081 aattttgaca aatctgatac ttttatagta ttttcttcgg tagaacgtat tggtatcgat
    13141 gattcttggg atgctatttt agagcaggtc tagcgatagg tgttgattta tctatgctaa
    13201 aacattctca gtagagggtg tttttcttat cgaaaacata aaaaatcata gttaggttta
    13261 ccgattttac ttgacgcctt aatgatgaca tgctagtatt ttatattaag gagatgagtc
    13321 atgacacaag tagcccaagg gcgctctaaa ggaaagtcat tgttatgcca tcaatgcaat
    13381 gccctttttg tatttattat ttttcttatc ttgcttgctg tactttttgg tgttcgatat
    13441 cgtaatagct ctattgaagg tatctggcga acaacaagca ttgatcagaa gttaggcgat
    13501 gattttgcta aacgtcttac tggtttgcat cagagccctc ttattgatga tagtttatta
    13561 acgtcatctc agatgatact aacagttaaa aataacaacg ttgacttgag ttttagtgtt
    13621 caagttgaac gagacatttt tgtcaaacgt ttagctgctt atcaccaaaa tgaattatta
    13681 aagacattaa aggaaaatca tttagttgtt ggtgacttga gtagtaaaga acgccaaatt
    13741 attgagaata gtatgccagc tagccatgaa ttagaaatga ttttagatca agcttttgag
    13801 aaattagctt ctcagatcgg aggcaaatat aatcaaaaaa caggacattt atctgctgtt
    13861 gttctcaaag gaaaagttaa tcgtattttg cacaccattg atatcaaaga agaagtagca
    13921 gcgggacata cttctttttc aaaaggattg ctcacaccta atggttattt tgattacacc
    13981 agatttggaa agaaacttga gttattaggc gatgaaaaaa ttatttttaa aaaagtgcta
    14041 aaaaaaagtc cgtcaagtgt ataacgtagt cacaagacgg attttttcat gttttgaaaa
    14101 ttattcaatt gaagaagttt attactgatc tttttgccta atcactagtt gtccttcttt
    14161 taggattgcc tgaagttttt tgacttctgg atggtcaaga taataatcag ttatacggtc
    14221 acgaatttcc tgttcgataa tacgtcgtaa tggacgagct cccatagcgt gattgtaccc
    14281 taaatctatc aaatgagctt tagcgtcatc agcaatcgtt aaactaatac ctttttttgc
    14341 ggtggtttga tttacttcag ctagcattaa atcaacaatt tcttctaaat tttctttttg
    14401 cagatgatta aatttaatga tactattaaa acggttcaaa aactctggtc tgaaataagg
    14461 tgcaatgcga tccataatgt taaacccaga agtttccgta tcttgttggc caaaaccggc
    14521 atttgatgta gcaataataa cggtattttt aaagttaata gtatttcctt gtccatctgt
    14581 caatcgtcca tcatctaaca cttgtagaag aagtgtaatg atttgaggat cagctttttc
    14641 aatttcatct agtaagacaa tagcataagg gttacgacga acacgctcag ttagggtatt
    14701 attattatca tcgtagccaa cataaccagc cgttgtccca atcaattttg acacagcagt
    14761 gcgatcgtta tattcggaca tatcaagtcg aataatagca tctttggaac caaataaatc
    14821 aagtgctaat tgtttagcta actctgtttt accaacacca gttggaccca caaaaaggaa
    14881 agaacctatt ggacggttac catcatcaaa acctgctcga tttcgtcgaa tagcacgtgc
    14941 tactgctgca acagcctcat cttgtccgat gacatggctt tttaagcggc tgctaattcc
    15001 tttgagcctt tctaaatcat tagtccccat gttagagaca ggaataccag ttaagcgctc
    15061 tacagactct gcgatatcat tgactgtagc agtaacattt tggctttggt tatgttgctc
    15121 aatttgcttt tgtaatgttt caatccgtgt ttttgctgct aaagcttttt caaagtcttc
    15181 tttggcgaca gctttttctt gactctcttt ttgtttagct atttcagttt cgagtgtttt
    15241 taagtcagtg accgggtgtt gcgcagctaa atgagcagct gtcatatcca gtaagtcaat
    15301 tgctttatct ggcaggctac gctgtgggat gtattgaata gaataatcaa cagcagcttt
    15361 tagaacatta tcaggaaggg taatatggtg gtgttgttca taaagattac gaatacacat
    15421 taaaatgtga aaagtatctt cagctgatgg tgcattcact ttaacttcat taaagcgacg
    15481 agcaagagca gcatttttta aaatagtatt gcggtattcg tcttgggtag tagcaccaat
    15541 cagtgttaat tctcctcgtg acaaggctgg tttaagaata tctgcaagtc cctttgagcc
    15601 tggatcactg cttgtggtac cagcaccaac tatttgatga atttcatcaa aaaataagat
    15661 gatattccca gcttctttta cttcttgaat caagttttga atggtccctt caaaggaacc
    15721 acgatactgt gtaccagctt caagactaga aatatcaatt gatacgattt ccttgttttt
    15781 aatagcagct gggacatctc cattaacaat ggcttgagct aaaccttcaa tgactgcagt
    15841 tttaccgaca ccagcatctc cgacaaggac aggattattt ttagttcgtc gtgccaagat
    15901 ttcagcggta tcttgaattt ctttgttacg accaatgacg gggtcaagat gcccttgacg
    15961 agcttcttgt gttaagttag ttccgagttg agtcaataca ctatcagctt taggtgttaa
    16021 catttgagaa gttgttgctt tggttgtcgc tacagggagt tgtcctgttt gacgatagtg
    16081 ttggaattct tcgggagtta tttcgcgacc gttaacgaga tagcggggat tttcgctacg
    16141 ataaccaccc atgtttgcca ttaattggtt gaaaatatca tccatattta caaaaggatc
    16201 tttaccagaa aaatgtgtca tatcagttac ctcgcaataa aaaatagact ataagatgtt
    16261 tgtaagcagt cgcagaatcg ttgttaggat ttcacatgat aggaaaccct ttgctaataa
    16321 aatgattcag acat
//
LOCUS       DAUNLR010000038        15819 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUNLR010000038 DAUNLR010000000
VERSION     DAUNLR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15819
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.038"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..390
                     /locus_tag="VLL59_001266"
     CDS             <1..390
                     /locus_tag="VLL59_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HER6509389.1"
                     /translation="KDGLPGKDGKDGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTAP
                     HTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETT
                     NPFFTAAAVAIMTTAGVVAVAKRQENN"
     gene            576..1013
                     /gene="msrB"
                     /locus_tag="VLL59_001267"
     CDS             576..1013
                     /gene="msrB"
                     /locus_tag="VLL59_001267"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HER6509390.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRIEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            1143..2162
                     /locus_tag="VLL59_001268"
     CDS             1143..2162
                     /locus_tag="VLL59_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HER6509391.1"
                     /translation="MSTYLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRIDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFATFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYQAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            2369..2794
                     /locus_tag="VLL59_001269"
     CDS             2369..2794
                     /locus_tag="VLL59_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HER6509392.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            2821..3312
                     /locus_tag="VLL59_001270"
     CDS             2821..3312
                     /locus_tag="VLL59_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HER6509393.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            3329..4138
                     /locus_tag="VLL59_001271"
     CDS             3329..4138
                     /locus_tag="VLL59_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HER6509394.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            4135..4962
                     /locus_tag="VLL59_001272"
     CDS             4135..4962
                     /locus_tag="VLL59_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HER6509395.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            5098..6747
                     /locus_tag="VLL59_001273"
     CDS             5098..6747
                     /locus_tag="VLL59_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6509396.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQGLLFASNPHLGNAFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            6751..7539
                     /locus_tag="VLL59_001274"
     CDS             6751..7539
                     /locus_tag="VLL59_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6509397.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            7533..8579
                     /locus_tag="VLL59_001275"
     CDS             7533..8579
                     /locus_tag="VLL59_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HER6509398.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNVAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            8695..10092
                     /locus_tag="VLL59_001276"
     CDS             8695..10092
                     /locus_tag="VLL59_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HER6509399.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSMPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLETGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLIKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            10194..11990
                     /gene="uvrC"
                     /locus_tag="VLL59_001277"
     CDS             10194..11990
                     /gene="uvrC"
                     /locus_tag="VLL59_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HER6509400.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            12175..12777
                     /locus_tag="VLL59_001278"
     CDS             12175..12777
                     /locus_tag="VLL59_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HER6509401.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            12902..14311
                     /gene="pepV"
                     /locus_tag="VLL59_001279"
     CDS             12902..14311
                     /gene="pepV"
                     /locus_tag="VLL59_001279"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HER6509402.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDQLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLNVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGTLSMNA
                     GVFTFDNQSADNTIALNFRYPKGTDAATLKAGLEKLPGLTKVSLSEHEHTPHYVPIDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(14379..15755)
                     /gene="mnmE"
                     /locus_tag="VLL59_001280"
     CDS             complement(14379..15755)
                     /gene="mnmE"
                     /locus_tag="VLL59_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HER6509403.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDWALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
BASE COUNT         4848 a         2896 c         3280 g         4795 t
ORIGIN      
        1 aaagatggtc tcccaggtaa ggacggcaaa gatggcaaag atggtcttcc aggtaaagac
       61 ggtaaggacg gtcaaccagg taaaccggct cctaaaacac cagaggtccc tcaaaaacca
      121 gataccgcac cacatactcc aaaaacccct cagatccctg gccaatcaaa agacgtgaca
      181 cctgctcctc aaaacccttc taatagaggt ctaaacaaac cacaaacaca aggtggtaat
      241 cagctcgcaa aaacaccagc agctcacgac acacacagac aattgccagc aacaggcgaa
      301 acaaccaatc cattctttac agcagctgct gtagctatca tgacgacagc tggagttgta
      361 gctgttgcaa aacgtcaaga aaacaactaa tcctcttttt gctacctaac tgatggaaag
      421 taaaactcag agagaacctc aaggttctct cttttttgaa tcaagatagt agctctaggt
      481 ataacgtctt gtctgaggtg ctgtgaacaa atcagttacc actcacctct ttttttggta
      541 aaatgtaagc actaagacat caaaaggagt tttccatgga aacatcagat gagttaaaac
      601 aacgcattgg tgacctttct tacgaggtca cccagcatgc agcaacagaa tctcccttta
      661 caggggaata tgatgatttt tttgagaagg gtatttatgt cgatatcgtc agtggtgagg
      721 tcttgttttc atcactggat aaatttaatt ctggctgtgg ttggcctgcc ttttcaaaac
      781 ctattgaaaa tcgtatggtc acaaaccacg atgactcttc ttatgggatg agacgaattg
      841 aggttaaaag ccgtgaagca ggatcgcatt tggggcatgt ctttagtgac ggccccaaag
      901 aagctggagg cttgcgttac tgtatcaatt cagcagctct taaattcatt ccttatgacc
      961 agatggaaaa agaaggctat gcccaatggc tcacattgtt tgatgaaaca taacagggtt
     1021 tcaaaatgac tgaaaaagaa gcgtcagtga ttcccacaag cactggattg gtgaggcgta
     1081 cgggtcaatt ttacaagcct ttgtaaaagg tctataatag ggaatgaaaa aaggaggtta
     1141 gtatgtcaac ttacttaaga aaacttccag gcctgttact ttgcttattg ttagctcttc
     1201 cagcctggtg tttagggcgc ttgtttccta ttattggagc tcctgttttt gctattcttt
     1261 taggaatgtt gttagccttg ttttatgaac atcgtgacaa gactaaagag ggaattagtt
     1321 ttacatccaa gtgtatttta caaacagcag tggttttgct tggttttgga ttaaacctaa
     1381 cccaagttat ggcagtgggc atgcagtctt taccgattat catttcaact attgcgacag
     1441 ctcttttggt agcttatggc tcacagaaat ggctgcgcat agatgtcaat acagccacct
     1501 tggtgggtgt agggtcttcc atttgtgggg ggtctgctat tgcagcgaca gctcctgtca
     1561 ttaaggcaaa ggatgacgag gttgctaagg caatttcagt catttttctc tttaatatgt
     1621 tagcagcttt gctatttcca agtttaggac aattactagg cttatctaat gaaggttttg
     1681 ctacttttgc tgggacagct gttaacgaca cctcttccgt gactgcaacg gccacggcct
     1741 gggatgccct tcaccattcc aatacactag atggcgcaac cattgttaaa ttgactcgca
     1801 ccttggctat tcttccaatt actttaggtt tatcccttta ccaagcgaaa aaagagcacg
     1861 acatcgttac agaagaaaac tttagcctta ggaagtcatt ccctcgtttt atcctcttct
     1921 ttttattagc ttccctcatc acgacattga tgaccagttt gggagtttct gccgatagtt
     1981 tccattacct aaaaacctta tcaaaattct ttatcgtgat ggctatggca gctatcggtt
     2041 taaatacaaa cctggttaaa ctgattaaga cgggcggtca ggctatcctt ttaggagcta
     2101 tttgctgggt agctatcacc cttgtcagtt tagccatgca attaagtttg ggcatttggt
     2161 aatcagacac gagaaatcag tttgactgat ttcttttttt gtatcttatt tgtgtagaat
     2221 tgtctacatt ttaaagagaa taatgcattt taaaaacgtt ttcatttgat aaaataaacc
     2281 tatcgttaaa ccagttcagt aaggacaact ggttgagata agcaattacc gtttactcag
     2341 cggtttttgt taatagagga ggataggaat gaaacgaaaa tttctcattg ggagtcacgg
     2401 cagactagcc agtggtttgc aaagctctat tgacatttta gcaggtatgg gacaggcact
     2461 tgaaaccatt gatgcttatg ttgatgatag tgattatact agccagattg atgactttat
     2521 cgctggggta gcagcagatg agcagggcct tatttttact gatttgttag gcggcagtgt
     2581 gaatcagaaa atggtaaccg ctgtaatgaa cagtggcaaa gacaatatct ttttaatcac
     2641 aaacagtaac ttagccactt tattgtcgtt ggtgttttta aaaccaggcg aagcgcttac
     2701 taaagatgaa attgtaaccg ttatcaatga atcgcaagtt cagttagtgg atttggtccc
     2761 tgagacaaat tcagaagatg acttttttga ttaatatctt aatatctagg aggaagacaa
     2821 atgattaccc aaattcgtgt tgacgaccgt ttgattcacg ggcaagtggc agttgtatgg
     2881 accaaagagt taaatgcgcc gcttttagta gtggctaatg atgaagctgc aaaaaatgaa
     2941 atcacacaaa tgacgcttaa aatggctgtg ccaaacggca tgaaactgct tatccgttct
     3001 gttgaagact cgattaagct ctttaatgat ccacgcgcaa ctgacaagcg gatttttgtg
     3061 attgtcaatt ctgttaaaga tgcttgtgcc attgctaaag aagttccaga cttagaagct
     3121 gttaatgtgg ctaatgtggg gcgttttgac aaatcagacc cagcaagcaa agtcaaagtg
     3181 acaccaagtc ttttacttaa cccagaagaa atggcagccg caaaggaatt agtcagttta
     3241 ccagaacttg atgtttttaa ccaagtctta ccatcaaata ccaaggtcca tttgagtcaa
     3301 ttagtcaact aaagagaggt aaaaaagtat gttagtacca gcaacaatgg cagctttagc
     3361 tgtattgatt tgttttgggg gaaattattt aaccggtcaa agcatgatgg aaagacccct
     3421 agtagttgga ctggtcacag gtcttctttt aggagatatg aaggtcggta tcttaatggg
     3481 ggcctctcta gaagctcttt tcctaggaaa tgtgaatatt gggggtgtta ttgcagctga
     3541 gcctgtaaca gcgaccgcca tggcaacaac ctttaccatt atttcacata ttgaccaaaa
     3601 agcagccatg accctagctg ttccaattgg aatgttggca gcctttgtgg ttatgttttt
     3661 gaaaaacgtc ttcatgaata tctttgctcc aatggttgat aaagctgcag cagctaacca
     3721 tcaaggtaaa ctagtgatgc tccactatgg cacttggatt atctattact tgatcattgc
     3781 ctctatttct ttcattggta ttttagtagg tagtggacct gttaatgcct ttgtggaaca
     3841 cattcctcaa aatctcatga atggcttgag tgctgcggga ggccttcttc cagctgtcgg
     3901 ttttgccatg ctgatgaaat tattgtggac caacaaatta gctgtttttt acctattggg
     3961 ctttgtctta acagcttatt tgaaattacc agcggttgca gttgctgccc taggagcagt
     4021 tatttgcgtc attagttccc aacgtgatct agaattagac gcaattacta gaggtgcaat
     4081 tagtaaacaa acaacctttg actctaaaga atcagaagag gaggacttct tcgcatgaca
     4141 tcacaagata atttgactaa agaagaccgt aaaatgcttc gctcagtctt ttggcgttca
     4201 tggacgatga atgctagtcg tactggggca acacaatacc acgcagtagg ggttatttac
     4261 actttactac cagtcatcaa tcgtttttat aagactgata aggataaagc agaggcactg
     4321 gtccgtcata caacatggtt caatgccacc atgcacatca ataactttat catgggtctt
     4381 gtggcatcga tggaaaagaa aaatagtgaa gatcctgatt ttgatgctag tgctattacg
     4441 gcggtaaaag catctctaat gggacctatc tctggagttg gagattcctt cttctgggga
     4501 attttaaggg ttattgcggc aggtatcggg atttccttgg caagtgcagg ctcagccatg
     4561 ggagctgttg tcttcttact cttgtacaat attcctgctt ttattattca ctactatagc
     4621 ctttatggtg gttattctgt aggtgcagga tttatcaaaa aactttacga atctggtggt
     4681 ataaaaatcg tcactaaaac ctcaagcatg cttgggttaa tgatggtagg ctcaatgacg
     4741 gcttcaaatg taaaatttaa aacgattctt acagttgctg cgaaaggtgc caaagaagca
     4801 gcttctattc aagattacct tgaccaattg tttattggta ttgtaccatt aatggtaaca
     4861 ctagcagctt tttggcttct acgaaagaaa gtgaatatca actggattat gtttggtatc
     4921 atgttccttg gcattatcct tggactttta ggtatttgct aataatctcc tagcaataaa
     4981 ggtaagtaag gcaagttttc ttgttttgct tacctttttc cttttaagat gatgagactt
     5041 gttttgatga aaaacgtagt agcattaaga aatttgttat aatgaaagga gcttaagatg
     5101 cgaggtgaac aggtggaaga acattttaaa aaacaattac aagatgatat ttctagacat
     5161 ttttcgtacc aatcgttaat gttatcattg ttgctaattg gtctttttat tattttttca
     5221 ttagcgccac aacaattagg cctctatcgt gatatcaatg ccactgcaac ccgttatcac
     5281 cgtttgatta gcaaacaaga agccttgctg gatgaattag ggaaaaatag cttactacct
     5341 tttttaaata aaaacctcag cactgctgat ttaagcaagc actattttca tttgcgccat
     5401 agcagccaaa cgtcaccaga acttttacta ttttcaccta gtcaaggcct tttatttgct
     5461 agtaacccac atttaggaaa tgcttttagt aaatctgttt atatccaaga agtcttgaga
     5521 gcagctcatc ctccaaaaac cttgtttaaa gttgctatgg atagtgaaga tggtcactac
     5581 ttgatgatca ttaagccaat gatagatcaa aaccaactaa agggatatgc ttttttagtg
     5641 atgagtggca aagattttct tcatcctaca aaaacattga cgtcagagtt ggtcattgct
     5701 gataagctgg acaacacgtt tacgttttcc aatcgtgagt ttatagcatc tagtctagat
     5761 aagatcaata gccagtattt acaccattat tttgtttttc aagataatcg agcctttatc
     5821 acaagaaagg ttgccttaca aggaggtctt tggctttaca tgtataggcc cttgattcca
     5881 atggtatcgg tgatgttatt ttcacttatt tcatcagctg ttatctttgt gattttgcaa
     5941 cgtaaatcaa gtggtttagc taaccgaatt gcagctaaaa attcaagagc aatcaatcaa
     6001 atggttagag atatgagtgc gatctctcgg caagaaaaaa gacgtattga ccttgagagt
     6061 caagatgaat ttcaatattt atctgatcaa atcaatcaaa tggtagagcg attgcaacag
     6121 ttacatgata aaacgttaga tttggaaact caaaaattat tatttgaaaa acggatgtta
     6181 gaagctcaat tcaatccgca tttcctctac aatacgctag aaaccatttt gattacgagc
     6241 cattatgatt ctgccctaac agaaaaaatt gttatccaat tgacaaaatt gttgcggtat
     6301 agtctcacgg attctagcaa acctgtcttg ctcaaagatg atttaagtgt catcgagtct
     6361 tatttagtga ttaatcaggt gcggtttgaa gaattgcaat atagcattaa cctatcccca
     6421 gaccttgata gtcttgcagt gcctaaattg ttcttgttac ctttgataga aaatgccatc
     6481 aaatatggct tgaaagaacg acacgatgtc aagattaaca ttgcttgtta ttatcaagat
     6541 gaccacatta ttttttctgt gagagataat ggttcgggaa ttgatgctca tcaccaaaaa
     6601 gtgattcgag agcaattgga agctggagag tcacaccatg ggttaattaa ctcttatcgt
     6661 cggcttaagt atcatttttc agaagtatcc ttggtttttg atcaaggtga taaacagttt
     6721 aatgttagtt accatgttaa ggagtagtct atgtacaaat tagtcattat tgaagatgaa
     6781 catattatta ggaaatggct gcgatacgct attgattata aagctttaga tattttggtc
     6841 attggcgagg ctaaagatgg caaagaagga gctgttttaa tcaaagagag tcaaccagat
     6901 atcgttttaa ccgatattaa catgcccatc atgacagctt ttgacatgtt tgaagcaaca
     6961 aaagatcaaa cttacgccaa aattatttta tctggctatg ccgattttcc aaatgcaagg
     7021 tctgccatac actacggtgt acttgaattt ttaacaaaac cgattgaaaa agcagctctt
     7081 tgggaatgtc ttcaaaccat tattgctaaa atagaaaagc aaaaggggtc taatcaaaaa
     7141 acagatgctt gcgtctatat tcccttaccc cagatgactg atcagattcc tgaagtagtc
     7201 aaagatattt tggagtgggt acatgctcat tttcaagaca agatcagcac gagccgccta
     7261 gctcatgact tagggtatag tgagagttat atctatcaaa atatcaaaaa gcatcttcag
     7321 atgcctttaa gtgattacat taatcaatat cggattaatc aggcaattca attgatgcaa
     7381 caagaaccag atttaatggt atatgaaata gcacaagctg taggtattta tgactatcgc
     7441 tattttgata gggtttttaa aaagtatcta ggacaaactg taaaggcttt taaagaagag
     7501 cattttatga aagataccga taggagtaag ccatgttaaa actcaaacgc aaatggctat
     7561 taagcttttt gttagtaata attattctag caatcgttaa cgttgcaatg tatatattct
     7621 catcgtcaaa aaaagatagt gctaaagaat tagttatctt gactcctaat agccaaacta
     7681 ttttaacagg gactattcca gcctttgagg aaaagtatgg ggttaaagta agattaatcc
     7741 aaggtgggac gggccaactt attgatcaat taggtcgaaa agataagcca ttaaacgctg
     7801 atattttctt tgggggcaat tacactcaat ttgaaagcca taaagattta tttgaatcct
     7861 atgtttctcc gcaggtttct actgtcattt cagattacca attgcctagt catcgtgcaa
     7921 ccccatatac gatcaatggc agtgtactga ttgttaataa cgaattagca agaggacttc
     7981 atattaccag ttatgaggat ttgctacaac cagctttaaa aggcaaaatt gcttttgctg
     8041 acccaaatag ctcatctagc gctttttcac aattaacaaa catcttactg gctaaaggag
     8101 gctatacgag ctcagaagct tgggagtatg tgaaacgttt attactgtct atgaattcta
     8161 tcagagcaac aagttcttca gatgtttacg aatctgttgc agaaggtaaa atgattgttg
     8221 gtttgaccta tgaagaccct tgcatcaatc tgcaaaaaag cggcgcaaac gtttcgattg
     8281 tttatcctga tgaggggaca gtatttgttc cgtcatcagt cgctattatc aaaaaagcaa
     8341 aggcaatgaa agaagctaag caatttatta attttatttt atcatcagat gtacaaaatg
     8401 cctttgggca gtcaactagt aatagaccta tccgacgaga tgctcaaacg agtcatgaaa
     8461 tgaaaccatt agatgaaatt attactttaa aagaagatta cggatatgtt actagacata
     8521 agaaaaaaat attgaatacc tataatcgac tacatgaagc attagaaaga ggaaagtaga
     8581 ctctaggctt gttgttgcta tactagtagt gttacaaaat agcgtagtca tttttttgaa
     8641 atcgatttca taatctggta gactaaggtt atcacgaaaa ggaggttata tgtgatggct
     8701 tatcaaacta tttaccctta tacaaatgaa gtccttcata catttgataa tatgaccgat
     8761 caaggtttgg cagatgtcct tgaaagagct caccttctct ataaaaaatg gcgcaaggaa
     8821 gatcatttag aagaacgtaa agcccagctt catcaagttg ctaatattct tcgccgtgac
     8881 cgcgataaat acgctgaaat catgaccaaa gacatgggaa aactgttcac agaagcccaa
     8941 ggtgaagtag atctttgtgc cgatattgct gattactacg ctgataaggc agatgaattt
     9001 ttgatgtcta tgccactaga aacggattca ggtcaagctt actatttgaa acaatcaact
     9061 ggtgttatcc tagctgttga gccttggaat tttccttact atcaaatcat gcgggtgttt
     9121 gcgccaaact ttattgttgg aaacccaatg gttttaaaac acgcgtccat ttgcccacgc
     9181 tctgcccaat cctttgaaga attagttctt gaaactggtg ctgaagcagg tagtattacc
     9241 aatttgttta tttcttatga ccaagtatca caagtgattg ctgataaacg tgtggttggt
     9301 gtctgcttga caggttccga acgtggagga gctagcattg cagaagaagc tggtaaaaac
     9361 ttgaaaaaaa caacccttga attgggtgga gatgatgcct ttattatcct tgatgacgcg
     9421 gattgggatc aattagagaa ggtgctttac ttctctcgtc tctacaatgc aggtcaagta
     9481 tgtacctcat cgaaacgttt tatcgtgctt gacaaagact atgaccgttt caaagaatta
     9541 ttaataaaag tcttcaaaac agctaaatgg ggtgacccaa tggatcccga aacgacgttg
     9601 gcgccattat catcagctca agctaaagca gatgttcttg accaaattaa gttggccttg
     9661 gatcatggtg cggagttggt ttatggtggt gaagcgattg atcatccagg tcattttgtc
     9721 atgccaacca ttattgctgg cctcacaaaa gacaacccta tttactatca agaaatcttt
     9781 ggcccagtcg gtgaaatcta caaagtgtct tctgaagaag aagcgattga agtggcgaat
     9841 gattctaact atggccttgg aggtactatc tttagtagca atcaagaaca tgcgaaagcc
     9901 gtagctgcta aaattgaaac tggtatgtct tttatcaact caggttggac aagtcttcca
     9961 gagctcccat ttggcgggat taaacattca ggctatggcc gtgaattgag tgagcttggc
    10021 tttacatctt ttgtgaatga acaccttatc tatattccga ataaaacgaa taatagcaat
    10081 actaaagttt gatctagatt gttaaaggag atctgctcgc cttaataaat aatcaaggcg
    10141 ttacactctt cttttttaaa gtcaaaattt taaaaatttg ataaactaat aacatgaacg
    10201 aactgattaa acataaacta gaactcttac cagacagccc tggctgttac ttacataaag
    10261 ataaagaagg aactattatc tatgtcggta aggctaagaa tttgaaaaaa cgcgtccggt
    10321 cctattttcg tgggagccat gataccaaaa cagagttatt agtatctgag attgtagatt
    10381 tcgaatatat tgtaacagag tcagataccg aagcgctttt gttggaaatt aacttgattc
    10441 aaaaaaatat gcctaagtac aacatcaagt taaaagatga taaatcttat ccctttctca
    10501 aaatcacaaa tgagtctttt cctcggttag tgattacaag atatattaag aaaaatgatg
    10561 gattgtactt tgggccctac ccagattctt acactgctaa tgaagttaaa aagttattag
    10621 ataggatttt tccatttaaa aagtgtaaaa atcctatcaa taaggtctgt ttttattacc
    10681 atttaggcca gtgctgtgct cataccattt gtcatacaga caaggcctat tgggatcgtt
    10741 taattgatga tgttaagcac tttttaaatg gtaaagatga caaaattatt gaagatcttc
    10801 gttctaagat gttagcagct tctgaagaaa tggcatttga acgtgccgct gaatatcgag
    10861 atttgatttc aggtattgcc accatgcgca ccaagcagcg ggtgatgagc aaggatttgc
    10921 aagatagaga tatctttggc tattatgttg ataagggatg gatgtgtgtc caagttttct
    10981 ttgtgcgtca agggaaatta attcagcgtg atgttaacct ttttccctat tataacgatg
    11041 cagaagaaga tttcttaact tatatggggc aattttacca agataaacag catttcatcc
    11101 ctaaagaagt ctttattcca gaagctattg atgaagaact ggtagccgct attgtgccaa
    11161 ccaaaatcat caaacccaaa cgcggtgaaa aaaaacaact ggtagctttg gctactaaga
    11221 atgctcgtgt tagtctgcaa caaaaatttg atttattaga aaaagatatc aaaaaaacga
    11281 gtggtgctat cgaaaattta ggtcagttac ttaagattga caagcctgtg cgcattgaag
    11341 cctttgataa ttctaacatt caagggacaa gtccagttgc ggctatggtt gtttttgttg
    11401 atggcaaacc tagtaagaaa gattatcgta aatttaagat taaaacagtg gtgggaccag
    11461 atgattatgc cagtatgaga gaagtgcttt ttcgaagata cagtcgggtg aaaaaggagg
    11521 gactgcaagc tcctaacttg attattgttg atggaggcgt tggacaagtc aatgtggcca
    11581 aagatgtgat agaaaaacaa cttggactca ctattcctgt tgcgggactt caaaaaaacg
    11641 ataagcacca gacccatgat ttgctttttg gaaacccact tgaagttgta ccgttgccgc
    11701 gccgttctga agagtttttc ttactgcatc ggattcaaga cgaagtgcat cgctttgcag
    11761 ttacatttca tagacaagtg cgacgtaaaa attctttttc atcaacatta gatcatattt
    11821 cagggcttgg cccaaagcga aaacagttat tactaagaca ctttaaaact ataacagcga
    11881 ttgcatcagc tacctctgag gagattcaag ctttaggtat acctaaaaca gtagttgaag
    11941 caatacagca acagataaca gacaataaaa atgatagatc gtctccttaa ataagtgtta
    12001 tgttttcagt actgacgagg taaaaaggcg ctacttgtta cgcacgacat ttcagttcgt
    12061 tattttgaaa ctttcagaaa gttgcgaagt gtagtgagtt tatgatttta aaaactattt
    12121 tatggtaaaa taaaatggta ttaaaaaaaa cagatttaga taggaagttt tgaaatgaaa
    12181 tttctagagt taaacaaaaa acgccatgcc attaagacct ttaatgacca gccagttgac
    12241 tacgaggatt tgcgaacagc cattgagatt gcaaccttag cacccagtgc caataacatt
    12301 caaccttgga aatttgtagt cgttcaagag aaaaaagctg agcttgctaa aggcttacct
    12361 ctagcaaata aagtgcaggt tgaacaggct caatatgtag tggcgctatt ttcagacact
    12421 gatttagctt tacgttctcg taaaattgcc cgtatcggtg tcaaatcgtt accagacgac
    12481 ttaattggtt attatatgga gactttgcca ccacgttttg ctgcttttaa tgaggttcaa
    12541 accggtgagt acttagctat taatgcaggc attgtggcta tgaacttggt gttatccttg
    12601 acggatcaaa agattgcttc caatattatc cttggttttg ataagtcaac gaccaatgag
    12661 attttagaca tcgatccgcg ttttcgtcca gaattattga ttactgttgg ctatagtgat
    12721 gagaaaccag aaccaagtta tcgtttgcct gttgatgaag tcatcgaaag aagatagagt
    12781 caggacaatt agttaaatgt aatgtccaga tgcgctactg agcgaccact attgttagac
    12841 tgatactatt ttggcttatt ttaagttaaa cattatccct aaaacgaata aggagagtat
    12901 aatgacaacc attgatttta aagcagaagt tgacaaacgt aaagaagcta tgctagcaga
    12961 tttagttgac ctattacgca ttaattcaga acgcgatgac caattagctg atgataaaca
    13021 cccatttggc ccaggtccag ttaaggcttt ggagcatttc ctcgcaatgg ctgagcgtga
    13081 tggctacaaa acgcgtaata ttgataacta tgcaggtgac tttgaatttg gtcaaggtga
    13141 tgaagtatta ggaatctttg gtcaccttga tgttgtccca gctggtagcg gttgggatac
    13201 agacccttat gagccagtga ttaaagacga tcgcatctat gcgcgtgggt cttcggatga
    13261 taaggggcca accatggcgt gctactacgc tctgaaaatc attaaagaat tgggtcttcc
    13321 tgtgtctaaa aaagttcgtt tcattgttgg taccgatgaa gaatctggct ggggggatat
    13381 ggattattac tttgcccata atggcttgaa aaatccagat tttggtttct caccagatgc
    13441 tgaatttcca attatcaatg gtgagaaagg aaatatcact gaatacctcc atttcgctgg
    13501 tgacaacaag ggcgcttttg tgcttcatcg cttccaaggt gggttgcgtg aaaacatggt
    13561 accagaatct gccacagctg tcattacggc accgcatgac cttaatgtgc tagaagcagc
    13621 cttggagcaa tttttatcag aacatggtgt taaaggttct atgaaggcta ctgatggtaa
    13681 aattgaagta actattattg gtaagtctgc tcacgggtcg actccagaag cgggtgttaa
    13741 tggtgccacc ttgctggcta aattcctgaa tcaatttacc tttgaagggg ctgctaagga
    13801 ttatttacat gtggcaggtg aggtgcttca tgaagacttt gcggcagaaa aactaggcct
    13861 tgcttatacc gatgaccgta tgggaacctt gagcatgaat gcgggtgtct tcacctttga
    13921 taatcaatca gctgacaata ccatcgcctt gaatttccgt tatccaaaag ggactgatgc
    13981 ggcaacctta aaagcaggat tggaaaaatt accaggatta actaaggtaa gcctttctga
    14041 gcatgaacat acacctcatt atgtgccaat agatgatgaa ttagtagcta ccttacttgc
    14101 tgtttacgaa aaacaaacag gtcttaaagg ctacgaacaa gttatcggcg gaggaacctt
    14161 tggtcgtttg ctagaacgtg gtgtggcctt tggagcgatg ttcccaggtg atgaaaacac
    14221 tatgcaccaa gctaatgaat atatgccttt agaaaatatt tatcgctcag cagctattta
    14281 tgctgaagca atctacgaat taattaaata agatgcttat gacagcaaaa agagctggaa
    14341 cactgttcca gctcttttgc gatgattaga gaatggtctt atttaccaag acagaattgg
    14401 ctaaagagtt gggtaatgag ttcatcagga gcagcatccc ctgtgatttc tccgagaatt
    14461 tcccaagttc tggttaaatc aacctgtagt aaatcaactg gcatgccaag ggctaaacca
    14521 tcattgacag cttctaaact ctggactgcc ttttcaatca aagaaatgtg gcgggcattt
    14581 gacaggtaag tggcatcttg ttctactagt ccagcattat caaagaagag ctggttgata
    14641 cgatcttcga ttagattaat gttctggttg gttaaaacgg aaatgggaat gtagtcatct
    14701 ggtaattgct ctaattcaat cttttgttcc aaatccgttt tattcaacaa tataatacgg
    14761 ttactgtcct gactgagatt taacaaagcc cagtcttggt cggtcagttt ttcagaagca
    14821 ttcagcacaa gaagaacaag gtcagcttct tgaagagctt ttttagaccg ttcaactccg
    14881 atttgttcga ccagatcatc tgtctcacga ataccggccg tatcgacaag ttttagagga
    14941 actcccttga tattaacgta ttcttcaatg acatctcggg tggttcctgc aatatcagtc
    15001 acaatagcct tgtcttctcg caacaaatta ttaagtaagc ttgacttacc gacgtttgga
    15061 cgaccaataa tagctgttga taagccctca cgcagaattt taccgcgttt agctgttcga
    15121 aggagatttt ccaaaaggct ttggaattct tgtgttttct cacgtagcag agcagtggtc
    15181 atttcttcca catcgtcgta ttcagggtag tcaatattga cttcgacttg agctaaggtg
    15241 ttgagaattt cctgacgggt gtcattgata agctgggaaa gggagccatc cagttgcttg
    15301 actgcaatcg tcatagcctt gtctgttttg gcacgaataa tgtccatgac agcctcagct
    15361 tgagtcaaat caactcgccc atttaagaag gcacgtttgg tgaattcgcc aggctctgcc
    15421 attctagcgc cttggcgaat caatagttgc aagatttcat ttgtcacagc aataccaccg
    15481 tgcgtattga tttcaaccac attttcacgg gtaaaggttt tgggggctag catgactgac
    15541 accataactt catcgataat agttcctgtc ttaggatcaa tgatatggcc atagttaatg
    15601 gtgtgtgagg cgacttgctc taagttcttt cccttaaaaa cagattgtgc aatggcaagc
    15661 gcatctgtcc cggatagacg aacaatgcca atagctcctt caccaagagg ggttgaaatg
    15721 gcggtaattg tatcaaattc tttagttata ctcatgccct ctattttaaa tcaagtccta
    15781 gtagaaagca aggtattatt ttgtatagaa aataggact
//
LOCUS       DAUNLR010000039        14815 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUNLR010000039 DAUNLR010000000
VERSION     DAUNLR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.039"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..1141
                     /locus_tag="VLL59_001281"
     CDS             <1..1141
                     /locus_tag="VLL59_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HER6509404.1"
                     /translation="FVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAYIS
                     KQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQEGDGFGGV
                     TIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDTETAHLYGE
                     LAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLNLFSYTAAF
                     SVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKL
                     IFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFK
                     KQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            1138..1824
                     /locus_tag="VLL59_001282"
     CDS             1138..1824
                     /locus_tag="VLL59_001282"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HER6509405.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            1918..3084
                     /gene="aroC"
                     /locus_tag="VLL59_001283"
     CDS             1918..3084
                     /gene="aroC"
                     /locus_tag="VLL59_001283"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HER6509406.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            3145..3486
                     /locus_tag="VLL59_001284"
     CDS             3145..3486
                     /locus_tag="VLL59_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HER6509407.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADTSASQLFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSPKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            3707..5059
                     /gene="gorA"
                     /locus_tag="VLL59_001285"
     CDS             3707..5059
                     /gene="gorA"
                     /locus_tag="VLL59_001285"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HER6509408.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKDKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDELPKRTAVVGAGYIAVELAGVLQALGSETDLFIRHDRPLRSFDKTIVDVLVDEM
                     AVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNAKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(5147..6415)
                     /locus_tag="VLL59_001286"
     CDS             complement(5147..6415)
                     /locus_tag="VLL59_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HER6509409.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQSISDLELAQCVSVI
                     RPILTKMSLETNWDGPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(6445..6885)
                     /locus_tag="VLL59_001287"
     CDS             complement(6445..6885)
                     /locus_tag="VLL59_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509410.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITISRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKATLP
                     SSSTTPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTNP"
     gene            7120..8262
                     /locus_tag="VLL59_001288"
     CDS             7120..8262
                     /locus_tag="VLL59_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HER6509411.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKVGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            8274..9488
                     /gene="thiI"
                     /locus_tag="VLL59_001289"
     CDS             8274..9488
                     /gene="thiI"
                     /locus_tag="VLL59_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HER6509412.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVYLNGTDYQPVVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            9526..10818
                     /locus_tag="VLL59_001290"
     CDS             9526..10818
                     /locus_tag="VLL59_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HER6509413.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTIQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPNYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    10923..10997
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            11032..11346
                     /gene="rplU"
                     /locus_tag="VLL59_001291"
     CDS             11032..11346
                     /gene="rplU"
                     /locus_tag="VLL59_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HER6509414.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            11358..11684
                     /locus_tag="VLL59_001292"
     CDS             11358..11684
                     /locus_tag="VLL59_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HER6509415.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            11712..12005
                     /gene="rpmA"
                     /locus_tag="VLL59_001293"
     CDS             11712..12005
                     /gene="rpmA"
                     /locus_tag="VLL59_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HER6509416.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            12353..13267
                     /locus_tag="VLL59_001294"
     CDS             12353..13267
                     /locus_tag="VLL59_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HER6509417.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            13264..13722
                     /locus_tag="VLL59_001295"
     CDS             13264..13722
                     /locus_tag="VLL59_001295"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HER6509418.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            13712..14602
                     /locus_tag="VLL59_001296"
     CDS             13712..14602
                     /locus_tag="VLL59_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HER6509419.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSVGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
BASE COUNT         4583 a         2590 c         3200 g         4442 t
ORIGIN      
        1 ttttgtcgaa aagaagctga cagcaggggt acaattatta gatgaaaaag atttttctaa
       61 tataaaggaa aaaaatcagt tggttcaact ggtgaccaag tccaatcgtc ccattggaac
      121 agcatatatc tctaagcaaa ataaaggaat tggttggtat ctaggaccag aaaaaatcga
      181 cttgtctatc tcttattttg ttagtctatt ttcagttgct aaagccaaaa gacaagattt
      241 tgctcaatcg gacgagacca atgcttatcg cctttttaat caagaaggag acggttttgg
      301 tggagtaaca attgatcttt ataaagattt tgcagtcttt tcatggtaca atgcctttgt
      361 ctatgacaaa aaagaaatga ttatggaggc ttttcaacag gtttttcctg aagtcaaagg
      421 agcttatgaa aagtgtcgct ttaaaggtcc agatactgaa actgctcatc tgtatggtga
      481 gctggcacaa gaaacctttt cgattttaga aaatggcata gcctatcaag tcttcttgaa
      541 tgagggctta atgacaggta tttttctaga ccagcatgat gttagaagag cactagtaga
      601 tggtttagct atgggcaagt cccttcttaa cctattttcc tatacagctg ccttttctgt
      661 agcagctgct atgggtggtg ctatcgagac cacttctgtg gacttggcta aacgatcgag
      721 agaattatca ctagctcatt ttgagcataa ccagttaaac ttagcctcac atcattttgt
      781 ggtgatggat gtttttgaat acttcaaata tgccaaacgg aaaaaattaa tctttgatgt
      841 gattgtgatt gacccaccaa gctttgctag aaataaaaaa caaactttct ctgtgagcag
      901 ggactaccac aaattaatca cagaggcctt ggacatattg agtcctaagg gaactattat
      961 agcttcaaca aatgctgcta atatgactgt tagccagttc aaaaagcaaa ttatcaaagg
     1021 atttggaagt cgtcgtcctg agtctatgac tctccagcag cttccgagtg actttactat
     1081 caataaagca gatgaaagaa gtaactattt aaaggtattt actataaagg tacgagaatg
     1141 agaattgtag caccagtcat gccaagacat tttgacgagg ctcaagccat tgatatttct
     1201 aaatatgaag atgttaattt gattgaatgg cgagcagact ttcttcccaa ggatgagatt
     1261 gtcgcagtag caccagctat ttttgaaaaa tttgccggaa aagaaattat ctttaccctt
     1321 cggaccgttc aagaaggggg gaatattacc ctttcaagtc aggagtatgt tgatattatc
     1381 aaagaaatca atgctattta taatccagac tatattgact ttgagtattt tacgcacaag
     1441 tcagtatttc aagaaatgct tgattttcca aatcttattt tgtcttatca caactttgaa
     1501 gagactcctg aaaatttaat ggaagctttt tcagaaatga ccaagttggc accgcgtgtg
     1561 gttaaaattg ctgtgatgcc ccagagtgaa caagatgttc tagatttgat gaactatacc
     1621 agaggcttta agacgctcaa tcctgagcaa gaatttgcaa ctatatctat ggggaaatta
     1681 ggaagattgt ctcgttttgc gggagatgtc attggctctt cctggacata cgtttcatta
     1741 gatcatgtta gcggtccagg tcaagtgact ctcaatgata tgaaacgtat tattgaggtc
     1801 ttagaaatgg atatctctaa ctagtgaatg gtctaaaaat attatttcta caatagttaa
     1861 gaaatgatgt ttttagatta atgtttttaa aataagtgga accaaaaagg agaaaaattg
     1921 cgttatttaa cagcaggaga atctcatggg ccatccttaa cagctattat tgaaggtata
     1981 ccagcaggat taactcttca tccagcggat attgatcacg aattacagcg acgtcaagga
     2041 ggttatggcc gtggtgccag aatgtctatt gagactgatc gggttcaaat atcctcagga
     2101 gttcgtcatg gcaaaacaac aggggccccc attaccttaa cggtaattaa taaggaccac
     2161 caaaaatggc tagatgtcat ggctgtagga gacattgaag agactctcaa gttaaagcgt
     2221 cgtgttaagc atcctagacc aggacatgcg gatttggtag gaggtattaa atatcatttt
     2281 aacgatttaa gagatgcctt agagcgttcc tcggctagag aaacaacgat gagagtggct
     2341 gtaggcgctg ttgctaaacg tatcttagct gaacttggaa ttgatatgtt acatcatatc
     2401 ttaatatttg gtggtataac gatcacaata ccttctaagc tctcttttag agagctgcaa
     2461 gaaagggctc tccattcaga attatctatt gttaatccaa agcaagaaga agaaattaaa
     2521 acgtatattg ataagataaa aaaagaaggg gatactattg gtggtattat cgaaacgata
     2581 gttcaagggg tgccagcagg tcttggatct tatgtccaat gggataaaaa attagatgcc
     2641 aagctggctc aagcagttct ttccattaat gcttttaaag gggtggaatt tggagttggg
     2701 tttgatatgg gattccaaaa gggttctcag gtaatggatg aaatcacctg gacacctacc
     2761 cagggctatg gtcgtcaaac aaaccactta ggtggctttg aaggtggcat gaccacagga
     2821 caacctcttg ttgttaaagg ggttatgaag cccattccta ctttgtataa accactcatg
     2881 tcggtagata ttgatagtca tgaaccttat aaagcaacgg tggaacgctc tgatccgacg
     2941 gccttaccag ctgcaggggt tatcatggaa aatgtggtgg cgacggtgct tgccaaagag
     3001 attttagaga ctttttcttc tactaccatg tctgaattgc aaaaagcttt ttcggactat
     3061 cgtgcctacg tcaagcaatt ttagatagcg agatactggc ttttatggta tcatacaggt
     3121 attaatgaac aaaaggagac tgtcatgtca caagaaattt atgactatgc taatcaactt
     3181 gaaagagcag ttcgtgctct gccagaatac caaaaagtgt tagaagtaaa agaggccatt
     3241 caagcagaca ctagtgctag ccaactgttt gatgagtttg tcgctatgca agaaaaaatc
     3301 caagggatga tgcaatcagg ccaaatgcca acggctgaag aacaaacaag cattcaagaa
     3361 cttagcccaa agattgaagc taatgaccag ctaaaagctt attttgaagc gcagcaggcc
     3421 ttatctgttt acatgagtga tattgagcgt atcgtctttg ctccgttgaa agatttagtc
     3481 aagtaagcca attaagatag gaaaaaaaca gactgctggc agctcgtcag gatctgtttt
     3541 ttagtgttta ttttctttgt atcagaaagt tgagcctctt tcttatttgt gatatagtca
     3601 aataaagtga ccaaaatagc aggccagtag tggctttaat gaaggcaagt tgtctgctaa
     3661 ctggctatgc taaaacatca gtattagaaa gtaaaaggtg ataaaaatgg ttattcctta
     3721 tgattatatt gttattggtg gagggagtgc aggtattgct tctgcgaaca gggcagccat
     3781 gcatggggcc aaagtattgt tagctgaagg taaagagatt gggggaacct gtgttaacct
     3841 aggctgcgtt cctaaaaaag tcatgtggta tggcgctcaa gtagcagata ttttagggac
     3901 ttacgctaag gattatggat ttgactttaa agacaaagca tttgatttta aacaattgaa
     3961 agcaaatcgt caagcttata ttgatcggat tcatgcttct tatgagcgag gctttgagca
     4021 gaatggtgtt gaccgtattt atgattatgc tgttttcaaa gatgctcata cggtagaaat
     4081 tgcagggcag ctttataccg caccgcatat tttgattgcc acaggaggac atcctgtttt
     4141 tccagatatt gagggggcac aatacggtat cagctcggac ggcttttttg ccttggatga
     4201 attacctaaa cgtacggctg tggttggagc aggctatatt gctgtggagc ttgctggtgt
     4261 tttacaggct ttggggtcag agacggattt atttattcgt cacgatcgac ctttaagaag
     4321 ttttgacaaa actattgttg atgtcttagt tgatgaaatg gcagttaatg ggccgcgttt
     4381 acacactcat gcagaagtgg caaaggttgt caaaaatact gatgagtcct tgacccttta
     4441 cctcaaagat ggccaagaag ttgaggttga ccagctcatt tgggctatcg gtcgcaagcc
     4501 taatctagaa ggttttagtc ttgacaaaac tggagtgacg ttaaatgata aaggttatat
     4561 tgagacagat gcctatgaaa acacgtctgt caaaggtatt tatgccgtgg gagatgttaa
     4621 tgcgaaactg gctttaactc cagttgctgt ggcagctgga cgtcgcctat cagagcgtct
     4681 tttcaatggc aaaacagacg agaaattgga ctaccaaaac gttgctactg tgatttttag
     4741 tcaccctgtt attggctctg ttggcttgtc agaagaagca gcagtcaaac agtatgggca
     4801 agaagcagtt aaaacatatc aatcacgttt tacgtctatg tttactgcta tcactaacca
     4861 tcgccaacct tgtctgatga agttggtaac agtcggagat accgaaaaaa tagttggtct
     4921 tcacggaatc ggatacgggg ttgacgaaat gattcagggc tttgcagtag ccatcaaaat
     4981 gggagcaacc aaggcggatt ttgataacac cgttgctatt cacccaactg gctcagaaga
     5041 atttgtcacc atgcgctaaa aaatgtagcc taaggcaata aaaaatgatg ttaacagttt
     5101 ttgaggaaag tcttctaaac tgctagcatc gttttttgtt aggtgattag gggaatatgt
     5161 ttttaaagat atttgcgttg ctcagacaat attgccttac ctcggagata aaataaagtg
     5221 accctgtaac aacaaagagt tcatcagatg ttacggaacc ttgtaaccag tctctgtaat
     5281 cttttacctg tgggtattta tcaggataat cctctaaaag atttgcttca gggaaatcaa
     5341 aagtcgtgac agatacttca aaagtatcta gttgagccag caagtcggct aaaggcttac
     5401 gtttgagacc tgcaaagaga atatgaatag gacgtttggg aaattcttct tgcagtagag
     5461 actttaattt agcaatggaa tctggattgt gagcgccgtc taatagaaga ttaggttgaa
     5521 taaattcgga ccggccaggc caagttgttg cctcaattcc tttttgaatc gtttttggag
     5581 atattttagg aaaggatttt ctaagtaatt gagctgtcat aatggctaaa caggcattcg
     5641 ctttttgatg ttgacctaat agtttgagac ggagtttggt taaattcaag ttatcgtgtt
     5701 gaaaggaaaa cgtcttttct gaaggattga gcaaaaaatc ttttcctaat tgatataagc
     5761 gtgaaccggc tttttgggta acttgttgaa agacttgact agcctcctgc tcaagttgac
     5821 cgataataac gggttcttta gctttgataa cttctgcttt ttggtgagca atttctgcta
     5881 ggctataacc taaacgttct tggtgatcaa aactaataga agggcatacg acggccagag
     5941 catgaaaaac attggttgcg tcggttttcc caccaatccc tgcctcaata atggcaatat
     6001 caacaggttt aagattggca aagtagcaaa acattatgag cgtcactaac tcaaactcgg
     6061 taggtccatc ccaatttgtt tcaagggaca ttttagtgag aatgggtcta atcacgctca
     6121 cacattgcgc caattctagg tctgaaatgg actggccatt aaggcaaatc cgatcgtgaa
     6181 aagagataat aaaaggagat gtaaaggttc cgacctgata accagaagtt gacaggatat
     6241 gctgtaagta ggctgtcaca gagcccttgc cgttagttcc aacaacgtga atagcaggga
     6301 atttgtcttg tggccggcct agtgcctcaa gtaaccaagc cattctggcc aaatcggtct
     6361 tgcgaccatt agccttaaag gtatgaatcc aggaaatgct atcataggta gtcattacta
     6421 tttcttgtcc ttctaacaat gcttttaagg gttcgtagga agaccagtat tagcatcttc
     6481 agctccagtt gcattaggaa gttgcgtccc ttcagtggtt gatggtgtct caggagctgt
     6541 aggagtagtc tcgttgtgag aaggtgtggt agaagatgac ggaagagttg ccttattatc
     6601 atctgtggtt tctgaagtac ctgtatggtt ttgattaccc tgagaagact ctttttcaat
     6661 aatcttgaca atggtattac tcgattcttt gggtgtatca ttagaggtct tatctggtac
     6721 aggctgcagt gctcttgaaa tggtaatggt tgccacaatg atactcaaaa tactaccaat
     6781 aagtgcaatg gatttttgga aagctgtaaa acctgtttta atatgctcgg tagggacacc
     6841 tcctgattta cgaggttttt gttgacggga ataacgtgat gacatatttt tctcctttaa
     6901 aatcatcgta atgccaagat taaggaggag gaaacagaag tcctagctcc tctttaacac
     6961 ttcatctatc agtataatct agaaaaaaag tgaagtcaac ggtttacctt atgtctagga
     7021 caaggaagtc ctttgggctt attgtaatac gaatattctt gatttcattt tagctatttt
     7081 gtgatagaat aaagtattga gtaaaaatga aggtgacaca tgatttattt tgataatgca
     7141 gccacaacca taccttatgg agaggctctt aaaacttacc aagaagtagc aacaaaaata
     7201 tatggcaatc cctcaagtct gcaccaatta gggacaaatg cgtctcgcat tttagaagct
     7261 tcccgtaaac agattgctgg tttgttgggt gttaagtcag aagaaatctt ttttacgtct
     7321 ggtgggactg aaagtgctaa ttgggctatt aagggaattg cttttgaaaa aactgctttt
     7381 ggcaaacata ttattatctc agccattgaa caccctgccg tgagtgaaag tgtcaaatgg
     7441 cttctcacac aaggattcga agtttcttat gctccagtga caacacaggg agttgttgat
     7501 gtgaatgctt tagctgagct gattagacca gacaccatct taatctcgat tatggctgtt
     7561 aataatgaaa tgggagctat ccaaccgatt agagccattt caaacctatt ggctaaccaa
     7621 ccaacgatca cctttcacgt tgatgctgtt caagccattg gtaaaatacc actctgtgat
     7681 tatatgacta atcgtgtgga tttggcttct ttttcagggc acaaatttca tagcgttcgt
     7741 ggtgttggct tcctttataa aaaagcaggc aagcgactca atcctctctt gtcaggcggc
     7801 ggccaagagc aggagttacg ttcaaccact gaaaatgttg caggaattgc tagcatggcc
     7861 aaagcattaa gaatagtcac tgaaaaacaa gtgagcgtct tacctaaact aacagcgatg
     7921 cgagatgtga tttacaaagc tttgtccgct tacccagatg tgacagtatt ttcagctcaa
     7981 gaaggctttg cgcccaatat tttgaccttt gggattagag gggttcgagg agaagttatt
     8041 gtccacgcct ttgaaaaata tgagatttat atttcgacca caagtgcatg ttcgtccaaa
     8101 gtaggtaagc cagcaggaag cctagtggct atggggattc ctgtaaaaac tgcccagaca
     8161 gccgttcgta ttagtctaga cgatgacaac gatatgggac aagtagagca gtttttgacc
     8221 atattcaaac agatttatga taaaacacag aaagttaggt aagattaggt aagatggact
     8281 attcagaaat tatggttcgc catggtgaac tatcaactaa agggaagaat cgcatgcgat
     8341 tcattaacaa acttaaaaac aatattcaag acgtactggc tcctttccca gccattactg
     8401 tccgttcaga tcgtgacaga actcatgtct atttgaatgg cacagattac cagccagttg
     8461 tagaagcttt aaagctggtg tttggtgttc aagctctatc tcctgtttat aaacttgaaa
     8521 aaagtgtccc tcttttggta acagctgttc aagatatcat gacttctctt tatcgtgatg
     8581 gactgacgtt taagattgcc actaagcgta gtgatcacgc gtttgaattg gatagtcgtg
     8641 agcttaacag tcttcttggt ggagctgttt ttgaggtttt accaaatatc caagcccaga
     8701 tgaaacatcc cgatgtgact ctcaaagtcg aaattcgtga tgaagcagct tacatttctt
     8761 atgaagagat taagggagca ggcgggttac cagtaggaac ttcagggaaa gggatgctga
     8821 tgttatcggg cggtattgat tcaccagtag ctgggtattt agcccttaaa cgtggccttg
     8881 atattgaagt tgttcatttt gctagccctc cgtacaccag tccaggtgcc ttggctaaag
     8941 cccaagacct tactcgtcgg ttaactcgtt ttggtggaaa tatccaattt atcgaggttc
     9001 cttttacaga aattcaagaa gaaattaaaa ataaggcacc agaggcttac cttatgacat
     9061 taacccgccg ctttatgatg cgcatcacag atgccattcg tgagcaacgt aagggtcttg
     9121 ttattgttaa cggtgagagc ctaggtcagg ttgctagtca aacccttgaa agcatgcagg
     9181 ccattaatgc ggtaacctca accccaatta ttagaccagt cgtgacaatg gataaacttg
     9241 aaattatcga gatggctcag gcgattgata cttttgacat ttctattcaa ccgttcgaag
     9301 attgctgtac tatttttgca ccagaccgtc ctaaaaccaa ccctaaacta ggtaatgctg
     9361 aaaaatatga agaacgcttt gatattgatg gtcttgtcca gcgtgctgtg tcaggaattg
     9421 ttgtcacaga aatcacacct gaaatcgtca atgatgaggt tgaaaatctt attgatgctt
     9481 tactttaaaa gaaaagatca aatgtaaatc ttttagtagt cagtaatgat actattgaaa
     9541 agcctctata agggcttttt tgctgcaatg aaggaggaaa attttgaggc aagatgttat
     9601 aatagagaaa aaggagggtg tgtcttgatt aaaactattc aatacaaaaa aacgatggca
     9661 acagttgttg ctcttatcgt cgcacttttg ctatttggct tgatttatga tttacttggg
     9721 gttcaaaaaa atgagctagc agctcaaaaa tctgctcagc caaaggtcaa aacagcgcgt
     9781 gttgtagcta atggcgacat tttaattcat gatattctct acatgagtgc tagaaaagct
     9841 gacgatacct atgatttcac tccttatttt gaatatgtta aggactggat tagcggtgct
     9901 gacttagcta ttggagatta tgaagggacc attagcccaa attatccctt agcaggctat
     9961 cccttattca atgctccaga agagattgca ggtgctctga aaaatactgg ctatgatgta
    10021 gtcgatttag cccataatca tatcttagat tcccaattag acggtgccct taacactaaa
    10081 aaggtttttc atcaattagg tatagacagt attggcatct atgacaagga tcgttcaaaa
    10141 gaatccttct taattaaaaa tgtcaatggt atcaaaattg caattttagg ttattcttat
    10201 ggttataacg gcatggaggc cacacttagc caagaagact atgagaaaca catgtctgat
    10261 ttagatgaag ctaagataaa aaaagaactt cagctagctg aaaaaaaggc tgacgtgacc
    10321 attgtcatgc cacaaatggg aacagaatat gccttagaac cgacagcaga gcaaaaagaa
    10381 ctttaccaca aaatgattga ttggggagct gacgtcgtcc taggaggcca tccgcatgtt
    10441 attgaacctt cagagacagt tataaaaggt aggcaaaaga aattcattat ttactctatg
    10501 ggaaatttta tttcaaatca gcggcttgaa accgtagatg atatctggac tgagcgtggc
    10561 ctattgatgg accttacttt tgagaaaaaa gataacaaaa caaaaattaa aacagttgag
    10621 gcccatccaa ccatggtttt agccaaaggt aaaggcattg tgggtaaaga aggttttgaa
    10681 ttatacaatt atcgaacaat ggttttagaa gattttatca aaggtggaaa ataccacgac
    10741 aagattgatg aggaaaccaa agcaaaagta gcacttgctt atcaggaaat taatgattta
    10801 gttaacctga aatggtaatg tttggtggtt tagcatctaa cgataaaaaa tagagattaa
    10861 acttaatttt tccttgataa aaagcagtta tggtgctaaa atagtaacgt tgactaaatg
    10921 cacatcctgt gcaaccgcgc gaaaatcgtt gtcaagtaga ccaagtctca cgattccagg
    10981 cgagtcttca cagagggaaa cctcaaacaa aaattttata ggaggtgcat catgagcaca
    11041 tacgcaatca tcaaaactgg tggaaaacaa gttaaagttg aagtaggtca agcaatctac
    11101 gttgagaaaa ttgacgctga agctggcgca gaagtcactt ttaacgaagt tgttcttgta
    11161 ggtggtgaca aaactgtagt tggtactcca gttgttgaag gagctactgt cgttggaact
    11221 gttgaaaaac aaggaaaaca aaagaaagtt gtaacattca aatacaaacc taaaaaaggt
    11281 agccaccgta aacaaggtca tcgtcaacct tacactaaag ttgtcatcaa cgcaatcaac
    11341 gcttaattta ctagcttatg attaaagcaa tttttactcg ccaaaaaaat ggtcaactga
    11401 gcagtgttac actgacaggt catgctggta gtggtaaaca tggctttgat attgtttgtg
    11461 cctctgttag tactctagcc attaactttg ttaattctct tgaggtgtta gcagattgcc
    11521 aagcattagt agatcttaat gatgttgaag gtgggtatat ggctattaca ataccaccac
    11581 atgacaacaa ggaggaagtt caattattat ttgaatcttt tcttctagga atgaccagtt
    11641 tggcgaagga ctcttcgaaa tttgtcaaca ctcaggtcat ctaaatttaa tttaagagag
    11701 gaaacaacat tatgttaaaa atgaatcttg ctaacttgca acttttcgcc cacaaaaaag
    11761 gtggaggttc tacatcaaac ggacgtgact cacaagctaa acgccttggt gctaaagctg
    11821 ctgacggtca aactgtttca ggtggatcaa tcctttaccg tcaacgtgga actcatatct
    11881 acccaggtgt aaacgtaggc cgtggtggag atgacacact ttttgctaaa gttgaaggtg
    11941 ttgtacgttt cgaacgtaaa ggacgcgata aaaaacaagt ttctgtttac ccagtagcta
    12001 aataattgtt taacatcgca ttatataagg ctttccaggt gtctggaaag ccgatttttt
    12061 tattttgcta ctcatttgct acccatattc taaaagccga tgtaggaaga gagcttgtca
    12121 gcagttttat cttttgagga tttagtaaca tgagcgtaga tattcatggt agtttggata
    12181 gtttcacgac caagtgtatt ggattttctt ctatcctact aaagattgta gttgcttatt
    12241 tagagcaata gttctaattg taaaaagtca gcataataaa acaatatcat aagatgttgt
    12301 tataacgggc tttatggtat aattaaggat actcatttta ggaaggaaag caatgaatat
    12361 tcaacaatta cgctatgtgg tagccatcgc taataatgga acttttcgag aagctgcctc
    12421 taaattgttt gtcagtcagc ctagcttatc agtttctatc aaagatttag aggcggaatt
    12481 agggtttcaa atttttaatc ggactacttc aggaacagtc ttgacaagtc aaggactagt
    12541 tttttatgag aaagctttag aagtagtcaa atcttttgat tcttttgaaa aaaccttttc
    12601 tcaagctgat ctggatcaaa atgaattttc tattgctagc caacattatg actttttgcc
    12661 acctcttatt acagcttttt cgcaacaata cgatggtcat cgtgtctttc gtatctttga
    12721 atcaacaact attcaaattt tagatgaagt tgctcaagga aacagtgaaa ttggtattat
    12781 ttacttgaat gtagacaatc aaaaaggtct ctttcagcgg atggataagc tgggcttgga
    12841 atatgtttct ctaattcctt tcactactca tatttatctt tcaaaaacgc atccattggc
    12901 taatcgcgaa gcgctttatt tgaacgatat tcaaggatta cctgcggtaa ggtttaccca
    12961 agaaagggac gagtatttgt attattctga aaattttgtg gatactagtg aatgccctcg
    13021 tatttataat gtgtcagata gggcaacctt gaacggtatt ttagagagaa ccaatgcctt
    13081 tgcgacagga tcaggttttc tcgatcatcg gagtgttaat gggattaaag tgatacctct
    13141 agctgatcat attgacaatc aaatgattta tgtcaaacga aaagataaaa acctttctgt
    13201 tgctggggcc acttttgtga ctattttaaa agactatttt gataaaagaa ggaaggcctt
    13261 aacatgaaaa aacgattgtt tgtgcttagc ttgatcctcc ttgtagcttt ggatcaactt
    13321 agtaaatttt ggattgtttc tcatatagcg cttggagaag tgaaaccctt tatcccaggt
    13381 atcgtcagct tgacttactt gcaaaacaat ggggctgcct tttccatatt gcaggaccag
    13441 caatggttct ttgttgtcat aacggtttta gttatcggtt atgctattta ttaccttgct
    13501 actcatcccc atttaaatat ctggaaacaa ttagctctct tgcttattat ttctggtgga
    13561 atcgggaatt ttattgatcg tttgcgttta gcttacgtga ttgatatggt tcatttagac
    13621 tttgtggatt ttgccatttt taatgtggca gattcatacc ttaccgttgg tgtcatatta
    13681 ttagtgatat gtttatggaa agaagaggat tatggaaatt aatgtgataa catcggggca
    13741 acgcttggat aaggcactag ctgatttaag tcccctgtca cgtggtcaag ccaatgacca
    13801 aattaagcaa ggccttgttt tagttaatgg tcagcaaaaa aaggctaaat atacggttca
    13861 agcaggagat gtgatttgtt ttgaactccc taaagaagaa gtcttagagt accaagctca
    13921 gaatattccc ttggacatta tctatgaaga tgatgctctc gccattatta acaagccaca
    13981 gggaatggta gttcaccctt cggtgggaca cccttcagga acaatggtta atgccttgat
    14041 gtatcatatc aaggatttgt cctcaatcaa tggtgtggtt cgtccaggaa ttgttcatcg
    14101 gattgataag gacacctcag gtctcttaat ggtagctaaa acagatgcag ctcatcaagc
    14161 cttggcagaa gaattaaagg ctaaaaaatc tctcagaaaa tacctcgcca ttgtccatgg
    14221 aaacctaccg aatgatcgcg ggatgattga agctcctata ggtcgtagcg aaaaggaccg
    14281 taaaaaacag gctgttacag caaaaggtaa agaagcagtg acacgtttta cagtgctaga
    14341 acgttttggc gattacagtc tagtggaatt acaactggaa actggtcgaa cgcaccaaat
    14401 tcgtgttcat atggcctata ttggtcatcc tgttgctggg gaccctttat atggaccacg
    14461 taagacacta tcaggtcatg gccaatttct tcatgcaaaa acattgggat taacgcatcc
    14521 tatgacagga aaagaaatga tatttactgt tgaagctccc gaaatttttc aaaaggtgtt
    14581 aaagctgcta agaaaaaaat aaacagcgag gagtagccat tatttttagt cttatatctt
    14641 tgtgtaaagt ttttaacatt ataaaaaata ctaaaaagca tttacgataa gccaggaaat
    14701 atgagaagtc ttttatgtta ttgggatatg caacatatct gttagagatc tttatttaaa
    14761 ctccttaaag aaaagagata ttccaaatag atgctaggta ttgtcttttt tactt
//
LOCUS       DAUNLR010000040        14754 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUNLR010000040 DAUNLR010000000
VERSION     DAUNLR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14754
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.040"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            186..1421
                     /gene="arcA"
                     /locus_tag="VLL59_001297"
     CDS             186..1421
                     /gene="arcA"
                     /locus_tag="VLL59_001297"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HER6509420.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1521..1949
                     /locus_tag="VLL59_001298"
     CDS             1521..1949
                     /locus_tag="VLL59_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HER6509421.1"
                     /translation="MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQTYGSKCLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            1989..3002
                     /gene="argF"
                     /locus_tag="VLL59_001299"
     CDS             1989..3002
                     /gene="argF"
                     /locus_tag="VLL59_001299"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HER6509422.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHILSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3172..4665
                     /locus_tag="VLL59_001300"
     CDS             3172..4665
                     /locus_tag="VLL59_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HER6509423.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVSKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINAWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4682..6013
                     /locus_tag="VLL59_001301"
     CDS             4682..6013
                     /locus_tag="VLL59_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HER6509424.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPKGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTEPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDLEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSKKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAAQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            6033..6983
                     /gene="arcC"
                     /locus_tag="VLL59_001302"
     CDS             6033..6983
                     /gene="arcC"
                     /locus_tag="VLL59_001302"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HER6509425.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7296..8288
                     /locus_tag="VLL59_001303"
     CDS             7296..8288
                     /locus_tag="VLL59_001303"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HER6509426.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKQHIGEVQTSVWPQEVRDSYDNIL"
     gene            8411..8950
                     /gene="rsmD"
                     /locus_tag="VLL59_001304"
     CDS             8411..8950
                     /gene="rsmD"
                     /locus_tag="VLL59_001304"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HER6509427.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLIEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8940..9431
                     /gene="coaD"
                     /locus_tag="VLL59_001305"
     CDS             8940..9431
                     /gene="coaD"
                     /locus_tag="VLL59_001305"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HER6509428.1"
                     /translation="MLTKVGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9418..10455
                     /locus_tag="VLL59_001306"
     CDS             9418..10455
                     /locus_tag="VLL59_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HER6509429.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10879..11856
                     /locus_tag="VLL59_001307"
     CDS             10879..11856
                     /locus_tag="VLL59_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HER6509430.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKRYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFESIQ
                     LEASYNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            12280..12924
                     /locus_tag="VLL59_001308"
     CDS             12280..12924
                     /locus_tag="VLL59_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HER6509431.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRISKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12928..14007
                     /gene="rlmN"
                     /locus_tag="VLL59_001309"
     CDS             12928..14007
                     /gene="rlmN"
                     /locus_tag="VLL59_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HER6509432.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(14089..14715)
                     /locus_tag="VLL59_001310"
     CDS             complement(14089..14715)
                     /locus_tag="VLL59_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HER6509433.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLMSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
BASE COUNT         4760 a         2581 c         3028 g         4385 t
ORIGIN      
        1 tacaagtaaa cgaatacaaa tctataaaaa taaaaataac gccccgaaaa tgtaagcgat
       61 tactcaaaat agctgtgaga aataccctat ttttatcttt tttaaggagt acactaggaa
      121 tataagcaag agttaagaat cttgacggtg aattcacaaa aaccaattag aaagaggtaa
      181 ttcttatgac tgctcaaaca ccaattcatg tttattctga aattggaaaa ttaaaaaaag
      241 tgttgctcca cagacccggt aaagaaattg aaaatcttat gccagactac ttggaacgct
      301 tgttgtttga tgatattcca ttcttagagg atgcccaaaa agaacatgat gcttttgccc
      361 aagctttgcg tgacgaaggt attgaagtct tgtaccttga gaccttagct gcagaatctc
      421 ttgtcactcc agaaattcgc gaagctttca tcgatgaata cctaagtgaa gctaatatcc
      481 gtggaagagc tactaaaaaa gccattcgtg aattgttgat ggctatcgaa gacaatcaag
      541 aattgattga aaaaaccatg gcaggagttc aaaaatctga acttccagag atcccagcat
      601 ctgaaaaagg cttgactgac ttggttgaat ccaattaccc atttgcgatc gacccaatgc
      661 caaaccttta tttcacacgg gacccattcg caactatcgg tacaggtgtt tctcttaacc
      721 acatgttctc agaaacacgt aaccgtgaaa ccctttatgg taaatacatt ttcactcatc
      781 acccaattta tgggggtggc aaagtgccta tggtttatga ccgtaatgaa accactcgca
      841 ttgaaggtgg ggacgaactt gttctttcaa aagatgtgct tgcggttggt atttctcaac
      901 gtacagatgc tgcttctatt gaaaaattgt tggttaacat ctttaaacaa aaccttggct
      961 tcaagaaagt attggccttt gaatttgcaa ataaccgtaa attcatgcac ttagacactg
     1021 tctttaccat ggttgactat gacaaattta ccattcaccc agaaattgaa ggcgatcttc
     1081 gcgtttactc tgtgacttat gacaacgaag aacttcatat tgttgaagaa aaaggtgatt
     1141 tagcagaact tcttgctgct aacctaggtg ttgaaaaagt tgaccttatc cgttgtggtg
     1201 gtgacaactt agtagcagca ggtcgtgaac aatggaacga tggttctaat accttgacca
     1261 tcgcaccagg tgtggttgtg gtttataacc gtaacaccat taccaatgcc attcttgaat
     1321 ctaaaggctt gaaattgatc aagattcacg gaagtgaatt ggttcgcggt cgtggtggac
     1381 ctcgttgtat gtcaatgcca tttgaacgtg aagatattta ataagctatg gtaaaggtgg
     1441 ttataggtca gaagcctttt taaagggcag ctagtgttta tcttcgcttc tgtgtctttg
     1501 tccttaaatg aaattttgtc atggcagata aatttgatgc caatgacgaa acaagaacgg
     1561 tttatgcagt cgtttacgac aatgaccagc ccgtttcaac aggacaattt ttagctgaaa
     1621 cgaaaataga agcacgattg acacgcattg taaccttagc agattattgt ggttgcggtt
     1681 atggtgccaa agtcactgaa gcgctagaaa cttataccag acgagaaggc ttttaccaac
     1741 taaccattca cagtgaactg acagcacaaa ccttttatga aaacctaggt tatcagacct
     1801 atggttccaa gtgtttagaa gatggtgagt attgtcagtc ccttgcaaaa accattctta
     1861 aatgggagaa gaatatggac atagcaatgc taattgcgat tgttggtggt ctattaggct
     1921 gctatctcta tctcacaaaa aataattaat caaaacagat tacagttaac actcgaagga
     1981 gacaatagat gacacaagta tttcaaggac gtagcttctt agcagaaaaa gattttacac
     2041 gcgctgaatt agaatacctt attgattttt cagcacattt gaaagatttg aaaaaacgtg
     2101 gtgtgcctca tcactactta gaaggtaaaa acattgccct cttgtttgaa aaaacatcaa
     2161 ctcgtacgcg tgcagctttt acaacagcag ccattgacct aggtgctcac ccagaatacc
     2221 ttggtgccaa tgacatccaa cttggtaaaa aagaatcaac tgaagacact gccaaagtat
     2281 tgggtcgtat gtttgatggg attgaattcc gtggctttag ccaacgcatg gttgaagaat
     2341 tggcagaatt ctcaggtgtg ccagtttgga atggtttgac tgatgaatgg cacccaaccc
     2401 aaatgcttgc tgactattta acagtgaaag aaaactttgg caaacttgaa ggccttaccc
     2461 ttgtttactg tggtgatgga cgtaataacg ttgccaattc ccttcttgtg actggtgcta
     2521 tccttggtgt taatgttcat atcctctcac caaaagaact cttcccagaa gaagagattg
     2581 tgacattggc tgaaggctat gctaaagaaa gtggcgctcg tatccttatc acggaagatg
     2641 ctgacgaagc tgttaaaggc gcagacgtgc tttacacaga tgtttgggta tcaatgggtg
     2701 aagaagacaa attcaaagaa cgtgttgaat tgcttcaacc atatcaagtc aacatggacc
     2761 ttgttcaaaa agcaggaaat gacaagctta tcttcttgca ctgcttgcca gctttccatg
     2821 acacaaacac cgtttatggt aaagacgttg ctgaaaaatt cggcgtgaaa gaaatggaag
     2881 tcactgatga agtcttccgc agcaaatacg ctcgtcattt tgatcaagct gaaaaccgta
     2941 tgcacactat caaagcggtt atggcagcaa cccttggtaa cctctttatt ccaaaagtgt
     3001 aataaggact ggtactcctt aactcatttc acatatcaat gtgatccctt taatttaaca
     3061 atttaactac ttaaaaacgt actttaacta catgacaagt cgttctggtt ttcgcgtcct
     3121 tgaccggaac tagaacggct tatttttatg aaaaggtaag aggtaatcat tatgacagaa
     3181 gaaaaaaaac ggggttttag aattccttct tcttacaccg ttctttttat cattatagcc
     3241 atcatggcag tgttaacttg gtttattcca gctggcgcct acgaaaccgc taagggcggt
     3301 ggtgttattt caggaaccta caaaacagta gcatccaatc ctcaaggatt ttttgacatc
     3361 ttgatggctc ccgttcgagg catgttaggt gttgaaggca ctgatggtgc tattcaagtg
     3421 tctttcttta tcttaatggt tgggggcttt ttaggagttg tcaacaaaac aggtgctctt
     3481 gacacaggaa ttgcgtcagt ggttagtaaa aacaaaggta gagaaaaaat gctgattgct
     3541 attttaatcc ctttgtttgc tctaggtgga acgacctatg gtatggggga agaaaccatg
     3601 gccttttacc cacttttaat tcctgttatg attgcggttg gttttgacag tattgttgct
     3661 gtagccatta ttttgattgg ttctcaaatt ggatgtctag cctccactat taacccattt
     3721 gcaactggtg tagcagctga tgctgctggt gtcagcattg cagatggaat gatttggcgt
     3781 gttatccaat gggttattct tgtcggcatg tctatttggt ttgtttacaa ttacgctagt
     3841 aagattgaag aagacccaag taaatcattg gttgcagata aggaagaaga gcataaggaa
     3901 ctcttccagt tgcaaaattc tggagaagac ttaaacaaac gccaacgaaa cgttttgacc
     3961 atttttactt tgacctttgt cattatgatt cttagtttga ttccgtggga agattttggt
     4021 atcaaattct ttactaatat caatgcttgg ttaaccacaa tgcctatctt agggggagtt
     4081 attgggaaaa ccatgggagc atttggtact tggtatttcc cagaaatcac catgctcttt
     4141 atcatgatgg gtgtcttagt tgctattgtt tatcgtatga gtgaagaaga cttttttagc
     4201 tcttttttga ctggtgcagg tgaattttta ggtgttgcca tgatctgtgc tattgcacgc
     4261 ggtattcaag ttatcatgaa tggtggtatg attacagcca ctatcttaca cttaggtgaa
     4321 acaagtcttt ctggtttatc ttctcaagtt tttgtgatat tagcttatat tttctacctc
     4381 ccaatgtcct tcttgattcc atcaacatca ggacttgctg gggctacaat gggaattatg
     4441 gcaccgcttg gacaattctc aaatgtccct gctcaccttg ttattacagc cttccagtca
     4501 gcttctggaa tcttaaacat gatttctcca acttcagcaa tcgttatggg agcacttgcg
     4561 cttggtcgcg ttgaccttgg tacttggtgg aaattcattg gtaaatttat tgtaatggtg
     4621 atgcttgtaa gcgtgctatt acttgtagtt gcaacattct tttaacagat aggaggttcc
     4681 tatggaatcc tatatcacac ctaaacatca agaggcttgt gtagctgcca ttaaacagat
     4741 cgtttcttac ccttctgttt gtcatgaagg agaaaatggc acaccttttg gacaggccat
     4801 tcaagatgtt ctcgaagcaa ccttagactt atgtcaaggt cttggtttcc atacttatat
     4861 tgatcctaaa ggttactatg gttatgctga gttaggtgac caaaaagagg tcttggctat
     4921 tctgtgccat ttggacgttg ttccagaagg agatcgtcag ttatggaaga cagagccttt
     4981 tgactgtgtt gaggcagacg gctgtttatt tggtcgaggc actcaagacg ataaagggcc
     5041 tactatgatg gcactatttg ccaccaaagc cttgatagat gcaggcgtta cctttaataa
     5101 acgcattcgt tttattttcg gaacagatga agaaactttg tggcggtgta tgaatcgcta
     5161 caatgattta gaagaacagg ctacctttgg gtttgctcct gattcaagtt tccctttaac
     5221 ctatgccgaa aaaggcctac ttcaggcaaa attagtgggg aaaggttctg ataaactgtc
     5281 acttgaaatc ggacaagcct acaatgttgt tcctgcaaga gcctcttatc aaggtgataa
     5341 gcttgaggct ttacaaaaag aactagataa gcttggcttt gagtacgtcg tcaaagaggg
     5401 agaattaacg gtttatggtc tcgcccaaca tgctaaagat gctcccgatg gcatcaacgc
     5461 tatgattagg cttgccaaag ctttagtggt ccttgaacct aacaaaaccc ttgattttct
     5521 tgctaatgtc attgatgaag atggcagagc acttaatatt tttggcagaa tcgaagatga
     5581 accttcaggc aaattaagct ttaatgccgc agggcttacc ttaaccaaag acaaggcaga
     5641 aattcgccta gatattcgga ttccagtttt ggcagataag gaaaaattag tccaacaatt
     5701 aagcaaaaaa gcacaagaat acggcctaac ctatgaagaa tttgattatt tggccccatt
     5761 atatgtgcca ttagacagtg aattggtaac aaccttgtta tctgtctatc ggaaaaaaac
     5821 aggtgatcaa agccctgccc aatcatcagg aggggcaacc tttgctagaa caatgaagaa
     5881 ttgtgttgcc tttggtgccc ttttccctga tgctgctcaa acggaacacc aagaaaatga
     5941 acatattgtt ttagcggatg cttaccgcgc tatggatatt tatgcggaag ctatttaccg
     6001 actaacgcga taacaagata tgaggagtaa ttatgacgaa acaaaaaatc gtagtcgcac
     6061 ttggaggaaa tgctattctt tcaacagatg cgtcagcaaa agcacaacaa gaagccttga
     6121 tttccacatc aaaatcattg gttaaattaa ttaaagaagg tcatgaagtc atcgtgaccc
     6181 acggcaatgg cccacaagtt ggtaatctct tattacaaca agcagcggca gattctgaaa
     6241 agaatccggc tatgcctttg gatacttgtg ttgccatgac agaaggtagc atcggttttt
     6301 ggttagttaa tgcccttgat aatgaattgc aagcccaagg tattcaaaaa gaagtggcag
     6361 ctgttgtcac tcaagtgatc gtggatgcca aagacccagc ttttgaaaac ccaacaaaac
     6421 caattggtcc atttcttacc gaagaagatg ccaaaaaaca aatggcggag tctggtgcaa
     6481 gtttcaaaga agatgcaggt cgtggctggc gtaaggttgt gccatcacca aaaccagttg
     6541 gtattaaaga agccaatgtc atcagaagtc tcgttgattc tggcgttgtt gtggttagtg
     6601 ctggtggtgg cggtgtgccc gttgtggaag atgctactag caagaccctg actggtgtgg
     6661 aagctgttat tgacaaggac tttgctagtc aaaccctttc agaattggtg gacgcagacc
     6721 tctttatcgt tttgacagga gttgataatg tttacgtcaa cttcaacaaa cctgaccaag
     6781 ccaaattgga agaagtgact gtctctcaaa tgaaagaata catcacacaa gaccaatttg
     6841 caccaggtag tatgttacca aaagtggaag ctgccattgc ttttgttgaa aacaaaccaa
     6901 atgctaaagc cattatcaca tcgctcgaaa atattgacaa tgtactatca gcaaacgctg
     6961 gaacacaaat tatcgcaggg taatcaagag gatttttagt tctgtttaaa agactcattt
     7021 aatggtattt tctgaagagt acgactgaca taaagagttg atactgtttt taaaggaaaa
     7081 gagtgtgcca taataaaaaa taatagtagt attagaaaag gctaatttta ttgagaatta
     7141 gccttttctt ttagctttga taggtgtata ataaccatac tattttttat ttttcaaaat
     7201 attagaataa acaaaagtgg acaacgtata aagagaactg ctaagtcgtt gagttcatta
     7261 gtcccaaaaa gattaccaaa aatgaaggag gagctatgaa gaaaagtttt attcatcaac
     7321 aagaggagat ttcctttgtt aagaatacgt tcactcagta tttgattgct aagttagatg
     7381 ttgttgaagt gcaaggaccc attttaagtc gggtcgggga cggtatgcaa gataatttgt
     7441 ccggtactga aaatccagta tctgtcaatg tcttgaaaat tcctaatgca acctttgaag
     7501 ttgtgcattc attagcaaaa tggaaacgtc acaccttagc ccgttttggg tttaatgaag
     7561 gtgaaggcct tgttgttaat atgaaggctc tccgacctga tgaggattca cttgaccaaa
     7621 cccattctgt ctatgttgac caatgggact gggaaaaagt catccctgat ggcaaacgta
     7681 atctcgctta cctcaaagaa accgttgaaa ccatttacaa ggtcattcgg ttaactgaat
     7741 tagctgtaga agctcgttat gatattgagg ctgttttacc taagaaaata accttcattc
     7801 ataccgaaga attggtagct aaataccctg atttgacgcc caaagaacgt gaaaatgcca
     7861 ttactaaaga atttggagca gtctttttaa ttggtattgg cggggtttta cctgacggta
     7921 aaccacacga tggccgcgct cctgactatg atgactggac aacagaaact gaaaatggct
     7981 atcatgggct taatggtgat attttggttt ggaatgacca acttggttca gcctttgaat
     8041 tatcctcaat ggggatccgt gtggatgaag aggccctaaa acgtcaggtg gaaatgactg
     8101 gtgaccaaga ccgcttagcc tttgattggc acaaatcttt gttgaatgga cttttccctc
     8161 taacgattgg tggaggaatc ggtcaatcac gtatggtcat gtttttgttg cgtaaacaac
     8221 atattggaga agttcagacc tccgtttggc cccaagaagt tcgtgatagc tacgataata
     8281 ttttataagt aatcacatca ttttgctaag ttttccagtt gtataagaga ctttaaataa
     8341 atgatcagaa atattgaaaa aagaaatcat ttttaaggtt tagagctaga aatttgctat
     8401 aataaatgtt atgagagttg tatcaggtga atttggtggg cgtcctttaa agacgctcga
     8461 tggaaagata acacgcccta cttcagacaa agttagaggt gcgattttta atatgatagg
     8521 accttacttt aatggtggtc gtgttttaga tttgtttgca ggttcaggtg gattagccat
     8581 tgaggctgtt tctcgtggga tgtctgctgc agttttgatt gagaagaatc gtaaagcgca
     8641 agctattatt caagacaata ttataatgac taaagctgag aatcggttta ccttgttaaa
     8701 aatggaagct gagcgagcta ttgattgctt gactggtcga tttgacttag tctttttaga
     8761 ccctccttat gccaaagaaa caattgtggc aactattgaa gctttagcag ctaaaaactt
     8821 attgagtgaa caggttatgg ttgtctgtga gacagataaa acagtcttgt tgccaaaaga
     8881 gattgcaacg ttaggtattt ggaaagaaaa aatttatgga attagtaagg taacagttta
     8941 tgttaactaa agtaggactt tatacagggt catttgatcc tgttacaaac ggtcatctcg
     9001 atattgttaa acgggcaagt ggcctatttg atcaaatata tgttgggatt tttgataatc
     9061 ctaccaaaaa aagctatttt aaactagaag ttcgtaaagc aatgcttact caagctctgg
     9121 ctgattttac aaatgtaatt gtagtaactt cgcacgaacg tttagctatt gatgtagcta
     9181 aagaattacg agtaactcac ttgattagag gcttgcgaaa tgcaactgac tttgagtatg
     9241 aagaaaattt ggaatatttt aatcaccttt tagctccaaa tattgaaacc gtctatttga
     9301 tatcaagaaa taaatggcag gcccttagct ctagtcgtgt gagagagcta attcattttc
     9361 agtcttcctt agaaggtttg gttcctcagt cggttattgc tcaagtggag aaaatgaatg
     9421 aaaagactta aaaaaatcaa atggtggtta gtgggtctgc tagctttaat ctctttgttg
     9481 ctagcgttat tttttccgct accttattat attgaaatgc ctggaggcgc ttacgatatt
     9541 cggactgtct tacaagtcaa tggcaaagaa gacaaacgaa aaggagctta ccagtttgtt
     9601 gcagtgggca ttagtcgtgc cagcctcgct cagctattat atgcttggct gacaccgttt
     9661 actgaaatta gtacagcaga agatacaaca ggcggataca gcgatgctga tttccttcga
     9721 attaatcaat tttacatgga aacatcacaa aatgcagcta tttatcaagc tttatcctta
     9781 gctggaaaac cagttacatt agattataaa ggcgtatatg ttttagacgt aaacaacgaa
     9841 tctactttta aaggaacgct acacttagca gatactgtaa caggtgtaaa tggtaaacag
     9901 tttactagtt cagcagaact tattgactat gtttctcacc taaaactagg ggatgaagtt
     9961 acggttcagt ttacgagtga taataagcct aaaaaaggag ttggccgtat tatcaaactg
    10021 aaaaatggga aaaatgggat tggcattgcc ttgactgatc atacaagtgt caattcagaa
    10081 gacacagtga tctttagtac taaaggagta ggaggaccta gtgctggtct aatgtttact
    10141 cttgatatat atgatcaaat aactaaagaa gatttacgca agggccgtac aattgcaggt
    10201 acaggaacta ttggcaagga tggcgaagta ggagatattg gtggtgcagg tcttaaagta
    10261 gttgcagcag ctgaagctgg tgcagatata ttttttgttc cgaataatcc tgttgataag
    10321 gaaattaaaa aagttaatcc aaatgctata agtaattacg aagaagccaa acgggcagcc
    10381 aaacgactaa agaccaaaat gaagattgtt cctgttacga ctgttcaaga ggcactggtt
    10441 tatcttcgca aataaaataa ctatgaatgt attatattca attatattca attatattca
    10501 cgctattaac tcataaaaaa cggttgaacc agatagacag atccttgacc agtcttttgg
    10561 gttcaatcat tttttacata aaacatatct aacttgacag cgtaaaaaag atgttataaa
    10621 agtctagtgg taaaaaggca atagagaatt gagtaaactt tagtcgatta tctggaaata
    10681 gagcatacta aaaacaccta gtgaaaattg atttttttca ctagctcatc caagaacttg
    10741 cgcagataat catgagtcca ttccatgact ctattattct ggaaagcctt gcaatagaca
    10801 agttaacgtt ataacaacta aattaaaaac ttgagattga aaaatcccca taaacttatt
    10861 ttacaaggag gtaaggctat ggtaaccatt aaacaagttg ctgaagaagc aggtgtttct
    10921 agatcaacag tctccaggta tatttctcaa aaaggatatg tatctgatga tgcaaggcat
    10981 aaaatcaaag cagcgatagc aaaattacat tacactccaa atgtcttggc gcagtcattg
    11041 aagacgaaaa aaaatcaact agtcggttta ttattaccag acatttccaa tccttttttt
    11101 ccgaggttag caagaggagc agaagaatat ttaaaagaaa agcggtatcg ggttatgcta
    11161 ggaaatattt cagacagcga agctcttgaa gaagaatacg tccatgtcct tcttcaaagc
    11221 aatgctgctg gcattattac tacccatgac tttacaaagc ggtatcctac tcttgctatt
    11281 ccagttgtag tggtagatcg tgttgaccaa gagacccagt acggtgtctt ttcagataat
    11341 agggcagggg gcttattggc ggctcagact gtctggcaag caggggcaaa agaagttttg
    11401 ttaataagag gtccgctgga taatgctgaa aacattaatg agcggtttga agctagtttt
    11461 tcttaccttc aaaaacaaga cgtgactatg tatgtgtgtg atagtcagaa ttttgatttt
    11521 gaaagtattc agctagaagc tagttacaac ctcaagtgtt acccaacaat agacagtatt
    11581 atagcacctt ctgatatcca tgctattgct tatattcatg aactgcattc tcaaggtaaa
    11641 aagattcctc aagatgttca aataataggt tatgatgaca ttttaatgag tcaatttatt
    11701 tatccttctt tatcgactat tcatcaatcc tcttatttga tgggccgtta tgccgccgaa
    11761 ttagtttata ctattgctag tcaattaact gtgaaagcaa atcggattaa attgcctgtt
    11821 cactacgttg agcgagaaac aataaggaaa agataagtaa taatattcgt ccagatttta
    11881 gcaggtatga tgaagattta ttgggattta ccttctactt taaaagaagt tatctgtcat
    11941 tactttcatc gctatcagtc aaaatgcatt cttatgcaac tcttaacctt aagcttaatg
    12001 tctttttgat aacatagagg aatgttacac gatgatgatg caataaagcc taaatatagt
    12061 aattgtcgtg attttatagc tagtgagtaa tgagatagca agtctctcat ttacttacaa
    12121 aagtcaaaaa atagtgtata atggttgagt tacagataac actgcaaaaa agataacaag
    12181 tgtccataat tatctaagac tataaaggcg atatagacag atataaaaaa gatgacgaat
    12241 cagttatcac tggacaatta accgatttag ttacaactaa tggatttttc agaaaggtgt
    12301 caaatgaaaa aagaaatttc gccagaaatg tacaactata ataaatttcc aggtcccaaa
    12361 tttattcatt ttgaagagca agttaaggct gaaggcattg atttgttact cttagaagat
    12421 gttaagaacg cttttgatac gactagcttt ggtcaacgtt atacagaagt tctcctaaag
    12481 tatgactata ttgttggcga ttggggaaat gaacagcttc gtcttaaagg gttttataag
    12541 gatagtgatg atatcaagaa aacgaatcgc atctcacgtt tagaagatta tattaaagaa
    12601 ttttgtaatt ttggttgtgc ttattttgtt ttagaaaatc ttcatccaca agatattaaa
    12661 tttgaagagg agcgccaacc aagacgaaag aaatcaccta aatcaaaatc aaatcgtcgc
    12721 aagccaaact attcaaatca gcagcccgca acacctaaga gtaaatcgaa gcggatatca
    12781 aaagaaaagc aacctgaaaa ccaagcgttt accagtcaaa aacgtcgaag taatactaag
    12841 cataaagaaa agtcaaaacg taatcagact agtcaactta ataccaaaat tagtcatttt
    12901 atcatcagaa agaaagataa ataatccatg aaaccatcga tttatagctt aacacgcgat
    12961 gaactgatcg cgtgggcagt tgaacgcggc caaaaacagt ttagagctac tcaaatttgg
    13021 gattggcttt ataaaaaaag agttcaatct tttgaggaga tgacgaatat ttctaaagat
    13081 tttgtttcta ttttaaatga tagtttctgt gtcaatcctt taaaacagcg agttgtacaa
    13141 gagtcagctg atggtacagt aaaatattta tttgaactgc ccgatggtat gttaattgaa
    13201 acagttttaa tgcgtcaaca ttatggtcat tctgtttgtg tgacgactca agttggctgt
    13261 aacattggct gtactttttg tgctagtgga ttgatcaaaa agcaacgtga tctaaacagt
    13321 ggggaaatta cagctcaaat catgttagtc caaaaatatt ttgacgatag aaagcaaggt
    13381 gagcgggtta gccatgttgt cgtaatgggc attggtgaac cttttgataa ttacaaaaat
    13441 gtcatgtgct ttcttcgcgt catcaacgat gataatggct tagcaattgg tgcccgtcat
    13501 attacagtct ctacctcagg gttagctcac aagattcggg attttgcaaa cgagggagta
    13561 caggttaatt tagcagtctc gttgcatgca ccaaataatg atttacgttc aagtattatg
    13621 cgagtaaatc gctcttttcc gcttgaaaag ctcttttcag ctatagaata ctatattgaa
    13681 aaaacgaatc gtcgtgtcac ttttgaatac attatgctaa atgaagttaa cgatagcatt
    13741 aagcaagctc aagaactagc agacttaact aaaactattc gtaagttatc ttatgttaac
    13801 ttgattccgt ataatcctgt ttcagaacat gatcagtata gtagaagtcc taaagagcga
    13861 gttctagcgt tttatgatgt gctaaagaaa aatggagtta actgtgtggt gcgtcaagag
    13921 cacggaacag atattgatgc agcctgtggc cagttacgtt ctaaaacgat gaaaaaagat
    13981 cgcgaaaagg ttacagcgac aaaataaagc ccaaaaaata tctttgattg acaatgcttg
    14041 atgacaaaat attcctagtc actaaaatga ctaggttttt tatctggcct aaaaatgctc
    14101 tagaagcaca atccaaaata atccaaaact aagataagga ataaaaggta tgcgcttgat
    14161 gcctaatagt aagcaagcag taatacctgc taaactagca agttgaatta gccaaatcaa
    14221 cgacattaga tccaatacta aagctaagct agcaaggtag aaaaaatcgc ctgctccaat
    14281 tgaaaaaggt cttaaatgag ctaataaacc tagtagcagt aatatcaatg ataaataatt
    14341 gatcgaataa aacaggagta gacttacaaa gctaaaaagc cacaagataa aagggtattc
    14401 ttgagaacgc caatcaaata aactaaataa taaagaaaag agtaacaagt aacagtaact
    14461 agcactaacc caatgtacca tactagccca taagataatt attagactta tctctaagct
    14521 aaagaagatt ttttgactag ttataaaatg gttttggaac tgccgaaaaa cgcgtttggc
    14581 aaaagttagt tggtcacaaa caatgacagt ctgtttactt agctgttctt gaccattatc
    14641 aggaaaataa agtagtaaac agtaaaaaag atgggttaat aagatgcccg aacatatact
    14701 aaaaaaagct atcatactta tttattcgaa aagaaatcaa atacttgcaa tctt
//
LOCUS       DAUNLR010000041        14653 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUNLR010000041 DAUNLR010000000
VERSION     DAUNLR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14653
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.041"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(14..1282)
                     /locus_tag="VLL59_001311"
     CDS             complement(14..1282)
                     /locus_tag="VLL59_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HER6509434.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYTVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQQYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
     gene            1372..2238
                     /locus_tag="VLL59_001312"
     CDS             1372..2238
                     /locus_tag="VLL59_001312"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HER6509435.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQNPVKHTISSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            2216..2773
                     /locus_tag="VLL59_001313"
     CDS             2216..2773
                     /locus_tag="VLL59_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HER6509436.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYSLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLL
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            2907..4451
                     /locus_tag="VLL59_001314"
     CDS             2907..4451
                     /locus_tag="VLL59_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HER6509437.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            4817..6040
                     /locus_tag="VLL59_001315"
     CDS             4817..6040
                     /locus_tag="VLL59_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HER6509438.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLILINQDITSTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPKVFQDAYQDGIIWTNMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
     gene            complement(6082..7644)
                     /gene="guaA"
                     /locus_tag="VLL59_001316"
     CDS             complement(6082..7644)
                     /gene="guaA"
                     /locus_tag="VLL59_001316"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HER6509439.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSDTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDILKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7811..9244
                     /locus_tag="VLL59_001317"
     CDS             7811..9244
                     /locus_tag="VLL59_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509440.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKKPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            9327..10025
                     /locus_tag="VLL59_001318"
     CDS             9327..10025
                     /locus_tag="VLL59_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6509441.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            10114..10455
                     /locus_tag="VLL59_001319"
     CDS             10114..10455
                     /locus_tag="VLL59_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HER6509442.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            10470..12032
                     /gene="ffh"
                     /locus_tag="VLL59_001320"
     CDS             10470..12032
                     /gene="ffh"
                     /locus_tag="VLL59_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HER6509443.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSSKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(12149..12847)
                     /locus_tag="VLL59_001321"
     CDS             complement(12149..12847)
                     /locus_tag="VLL59_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509444.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAVYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            13292..14362
                     /gene="xerS"
                     /locus_tag="VLL59_001322"
     CDS             13292..14362
                     /gene="xerS"
                     /locus_tag="VLL59_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HER6509445.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT         4836 a         2426 c         2792 g         4599 t
ORIGIN      
        1 gtacgaagaa aagttagttg ctctttccac aagtattttt gattagtgag tttaatttgc
       61 tttgtatttg ttgattgata gcaatagaga gatagcgttt ttttccagtt attattattc
      121 tatcagattt atctaatgta aagtttctat aagagtctga tgtcgtgtaa tcaatcacta
      181 aatgagtagg ggttagttga tagtgaatat cagggcaatt ttgttttaaa aagagagcca
      241 attgacgttc ccgctgtttt agataacgct taataaagcg aagatttttt tgaaacatcc
      301 cattttctaa ataaagagct aatgcttttt gcattagtaa gttcgtgtct aaatcaatca
      361 gtgatttttg ggttaaaaaa tgaggtttta aacctgatgg taaaactaga gctccgatac
      421 ggagtgcagg aaaaacactc attgaaaaag attttaggta gatgattcgg tgatgagtgt
      481 cataataatg aattggtggc tctttaagtt tcacaaaatc tcctaaataa tcatcttcta
      541 aaatataaac ctggtattgt tgtgctagac gaacaatagc ttccttttcc ttagtgctat
      601 aagaaagtcc cagaggatgt gaaaatcgtg aaatcgtgta aaaaaattta atatcaccag
      661 tttgaaataa agattctaag agttctaaat caaggccatt aaagtgtcta gagatagttt
      721 gatagggtaa tcctaactga gcaacaatag cttccatccg atgataagta ggcttttcaa
      781 ggagaattgt tttgcccgca ttaggaaaag gcatttgtga taaaatataa agcgcttgtt
      841 gcgtcccaga ggtgattaat agttggtctt tgttactgta aacactattt tcagctaagt
      901 aaagaagcaa agcttccctt agttcttcta gtccttcggt tttgtgataa taatgaaaga
      961 ggtatttgtc tttagcactt aaagcctcat ttaagcagag tcggaaatct tcataagcca
     1021 tattattata atcttcaaga cttagattaa gaacattatc gggcatgctt acgttaccca
     1081 aaacataata accactttta ggaacagtat aaattaagtg acgatatttt aattctaaaa
     1141 gagcccgctg aacagtatct ttgctacaat gataaacctt acttaatacc ctaattgaag
     1201 gtagcttgtc cccttttttt agtcgctgtt tctggatatc ttgttcgata ttggaaatga
     1261 ttgtttgata ttttgttgtc ataaattgtc cccatacagt taagtgttat aactattgta
     1321 tcttatgcct ctttttctta caatagttat tatagaaaag aggtaatagc tatgaaacgg
     1381 attattgtgg caaatgatct ggttggtgtt ggtaaggtag ctttgtctgc tagtattcct
     1441 ttaatggctt cttgtttgtt agagcaagtt ttattaccaa cttgcctttt atcaagccat
     1501 actggcggag gacagaaccc tgtgaagcat actatatcaa gtatattaga cgttttttta
     1561 acagattggg acaacaaaag aattaagttt gacggcatct ttataggtta ttttacgaca
     1621 acaagagatg ggcaaaagct gctagaatgg ctttcaagaa agcaacttcc cttaatttta
     1681 gatccaatta tggcagataa tggaaaactt tatcaaggct tcagtcaaaa acatatagag
     1741 attatgataa aacttactca aaaagctgag cttgttttac ctaatattag tgaggcttgt
     1801 ctattaacac aaacagctta tttagcaaaa aattatgatg aagaagatat tagacaggtg
     1861 gctagaaaat tagctaagct tggacctaaa caggttgtca ttagcggaat ctcttttgag
     1921 gagggcagca ttggttttgc ttactatcag tcagattcag atcaattaac attccatttt
     1981 gggaagcaat tcccttacca tttctatggt acaggagata tagcatcagc tattataaca
     2041 gcaggattct attatcagct accactaaca caaattctag atcttgttgt ttcatttctt
     2101 gaaaaagtat tgcaaaatac ccttacatta aaaagagatt taatcttagg tgttgcttat
     2161 gaatctcatt taaattactt aactaaatcg tttaaaaagt tgttggagga aaaaaatgtc
     2221 atctcaaaaa ttagctaatt atattgaatt gagtatgtat gccgctttaa tttttatttc
     2281 agtacaagta ttgcgtatcc ctgtcggtat gcagtttatt catcttggca atgcattagt
     2341 tgttattgca gtcttaatct atggtagtaa aaaaggagct ctagttgcta gtcttggttt
     2401 agggatcttt gatgttttga atggctatgc ttcagtcgtt tggataacta tcttagaatc
     2461 cttggctatt tgtttaattt tgcatttggt atatgaaaga gctatgcaat ctagtaaaaa
     2521 accaaaagcc attataacaa taacagttat tgctgcattg tcaaaattaa ctattaacct
     2581 tataaaatac tcactgttag cttatatagg tactcagcta ccactttcgg tatctttttg
     2641 ggtagctctt ggaaaaattg gtggtagttt cggaacatct tttgtgactt tacttgctgt
     2701 tcctcttttg tatcctgtta tcaaaaactt aaaagaaaag gttacaatcg gacaagcaaa
     2761 aagaggtttt tgatacaagt accttatcga taaaaaagca aggtacactt ttagtcaaat
     2821 attgacaaaa ggttacaatt ttgccataat gaaataacta taaagccgtt ttgacggctt
     2881 ttttgatgac agttaaggaa gaaacgatga gtattttaga agttaagcag ttgagtcacg
     2941 gttttgggga tcgggctatt tttgaaaatg tgtcatttcg cctcttaaaa ggtgaacata
     3001 ttggactagt tggggcaaat ggtgaaggaa aatcaacctt tatgagtata gtcacaggac
     3061 atttacagcc tgacgaagga aaagtagagt ggtcgaagta tgtcactgca ggttacctgg
     3121 atcaacatac agtgttggaa tcaggacaaa ccgttcgtga tgtcttgcga actgcttttg
     3181 atgagttatt taagaccgag aatcgtatta atgagattta cgcgtcaatg gcagatgata
     3241 aagctgatat tgctgttttg atggaagaag taggtgagct tcaagatcgt ttagaaagtc
     3301 gtgatttcta tactttggat gctaagattg atgaagtagc gcgtgcgctt ggtgttatgg
     3361 attttggaat ggagtcagat gttacatcct tatcaggtgg gcaacgaaca aaggttttat
     3421 tagccaaatt actattagaa aaacctgata ttctgctatt agatgaacca actaaccatt
     3481 tggatgctga gcatattgaa tggttaaaac gctatttaca acattatgaa aatgcttttg
     3541 tgttgatttc gcatgatatt tctttcttaa atgatgtgat taatattgtt tatcatgttg
     3601 aaaatcaaag tttagttcgc tatactgggg attattacca atttcaagct gtttatgaga
     3661 tgaaacaatc tcaacttgaa gcagcctatg aacgtcaaca aaaagagatt gctaacttgc
     3721 aggattttgt caaccgaaat aaggctcggg tagcgacacg taacatggca atgtctcgcc
     3781 aaaaaaaact tgataagatg gatataattg aacttcaagc tgagaaacca aaaccaaatt
     3841 ttgaatttaa gcaagctaga actcccagcc gattcatttt tcaaacaaaa aatcttgtga
     3901 ttggttatga ttacccattg accaaagaac ccttaaatat aacgtttgaa agaaatcaaa
     3961 aaattgctat tgttggggcc aacggtattg gaaaatctac tttgctaaaa agtttattag
     4021 gtgttattga gcctttagaa ggtcatattg tcacagggga ttttttagaa gttggctact
     4081 ttgaacaaga agtgacaggt gttaaccgac aaactccgct agaagtagtt tgggatgctt
     4141 ttcctgcctt aaatcaggca gaagttcgag cggcactagc tcgttgcgga ctaacatcaa
     4201 aacatatcga aagtcaaatt caagtacttt cgggtggtga acaagcaaaa gttcgttttt
     4261 gtttgttgat gaatcgtgaa aataacgtgc ttattttaga cgaaccaaca aatcatcttg
     4321 atattgatgc taaaaatgag ctcaaacgtg ctttaaaagc atataagggt tctattttaa
     4381 tggtttgtca tgaacctgat ttctacaatg ggtgggtaac cgatacttgg gattttagta
     4441 agttaaccta aactattcct taatttttta cacaggaatt actaaaatca gtaaagatat
     4501 agaataaata ctgctagata tgtgatggtt taggtaactg atcaccaacc aaaaaaagat
     4561 gtgactacat ctttttttta tctaatggaa tggtgtaaag tcgtttaata atagcttatt
     4621 ttttgatgat cagttgttca tgaaattgtt ggtgattaac aagtcattta agatacaaac
     4681 gttattacta aaaagtgatt caaatagttt ccctattttt atgttttttt aaaatttatt
     4741 acgaataaat agataaagac agtgaagata cttagtaagt acatctgcta agattacgaa
     4801 tagatgggga caatatatga cgaatttaac gttttatgca aaaatcggta tttcagaaga
     4861 agagcatgac tcttttgtta aagaacatca gcaaattagc gttttacaag gtagtgattg
     4921 ggcgaaaatc aaaaatcaat ggcagaatga gcgaattggt atctataaag aggaaaagca
     4981 ggttgcctct ttatcacttt tgattaagct attgccactt ggaagaagca ttatttatat
     5041 tccaagaggg ccagtcatgg attaccttga ccgtgatttg gtggcattta ccatgaaaac
     5101 actaaaggat tatggtaaaa ctaaaaaggc cctctttatc aaatatgatc cagctatcct
     5161 gttaaaacaa tacgcactgg gacaggaaga agaagaaaaa cctttagctt tagcagctat
     5221 taagaatctc caagaagctg gtgttcattg gactggttta acaatggaga ttgcagatag
     5281 tatccaacct cgtttccaag ctaatattta cactcaagaa aaccttgaga tgcaatttcc
     5341 taagcatacc agacgtttaa taaaagatgc taagcagcgt ggtgtagaaa catatcgtgc
     5401 cagtcaatca gaacttcaca aattttccaa gattgtctcc ttaacagaaa aacgtaaaaa
     5461 tatttctttg cgtaacgaag cttactttca aaagttgatg actacttatg gagataaggc
     5521 ctacttacat ctagcaaaag tgaatattcc tcaaaaacta gatcaatacc gccagcaatt
     5581 aattcttatt aaccaagata ttactagcac ccaagctcat caaaagaagc gtttaaaaaa
     5641 attagaagat caaaaagctt ctttagaacg ttatataact gaatttgaag gttttacaga
     5701 ccaatatcct gaggaagttg ttgtagcagg tatattatct atttcttatg gaaatgttat
     5761 ggaaatgctt tatgctggga tgaatgatga ttttaagaag ttttatcctc agtatctgct
     5821 gtatcctaaa gtttttcagg atgcttatca agatggtatt atttggacta acatgggagg
     5881 agtagaaggc tcgcttgatg atggacttac caaatttaag gccaactttg ctccgacaat
     5941 agaagaattt ataggagaat ttaatctccc tgtcagccca ctttatcata ttgctaatac
     6001 catgtacaaa atacgaaaac agttaaagaa taaacattaa aagactcgcc aaaatgagcg
     6061 agtcttttaa tgtttattct gttattccca ttcaactgtt gcgggtggtt tacttgtgat
     6121 gtcgtagacg atacggttaa cgtggtcaac ttcgtttacg atacgtgttg agattttttt
     6181 caagatatcc caaggaagtt gagcaaagtc agctgtcatg ccatcgatag acgtaatagc
     6241 acgaatggcg atggtataat cataagtacg accatctccc atgacgccta cagaacggac
     6301 acctgtgtta actgtaaagt attgccacac gtcacgatca agtccagcct tagcaatttc
     6361 ttcacgaagg atagcgtctg attcgcgaac ggtttcaagt ttttcttcag taattgctcc
     6421 catgacacgg atagcaagtc caggacctgg aaatggttgg cgccaaacaa tttcttcagg
     6481 cattccaaga gcgattccaa gcgctcgaac ttcatctttg aaaagagtgt ttaagggctc
     6541 aatcaattca aactgcatgt cttctgggag accacccaca ttgtgatgtg atttgatggt
     6601 ttgagcagtt tctgttcctg actcaatgat atcagtataa agtgttcctt gggcaaggaa
     6661 gtcaacacct tttaatttgc tggcttcatc atcaaaaaca tagacaaatt cattaccaat
     6721 aattttacgt tttttctcag gatcttcaac gtctgcaaga aggtctaaga aacgttttga
     6781 agcatccaca cggataatat ttaggccaaa tttgccccca agcattccca taacttgatc
     6841 gccctcgtct ttacgaagaa gaccgtgatc aacgaaaata caagttaatt ggtcaccgat
     6901 agctttttga agtagaacac caacaactga agaatcaact ccaccagaaa gacctagaag
     6961 aactttacga tcgcctacag tttcacgaat tttagcaatt tccatgtcaa taaaattatc
     7021 cattgaccaa tcaccacgcg cgccacaaat tgatatagca aagtttttaa gaatgtcatt
     7081 tccataaaca gagtgtctca cttctgggtg gaactgaata ccgtagaggt ttttctcagt
     7141 attttcaata gctgcatagg gacagtcatt tgagtctcca acaaggtgga aaccttctgg
     7201 aatttcagta acagcatcac catggctcat caaaacgagt tgttcttgag gtgtgtctga
     7261 aaataatttt gacgtttcac gaagatgaag ggttgactga ccgtattcac gattaccagc
     7321 ttgtccagca ggaacaactt taccacctaa tttatgggtg attaattgca taccgtaaca
     7381 gataccaaga atcggaatcc ctagttcaaa gatttcaggg tcaatgccaa aggcgttatc
     7441 agcgtaaaca gagttaggac ctcctgataa aacgatacct atgggattga tctcacgaag
     7501 ttcttgagcg gtgattttat ggctttttag ttcggagaaa acaccaaact ctcgaatacg
     7561 tctagcaata agctgattgt actggctacc ataatcaaga acgataattt tttgaacatc
     7621 attcaaaatt gaaatttcag tcattataat cctttcattc tataccaacc gtcaggctga
     7681 tagttgtcaa cttattgtag catattttca tcgaaaagac attacaattt ctctagctcg
     7741 ttggaaaaaa acgtaatcgt tatgttacaa tagaggctat gaaagggaat taagacaaca
     7801 gggagggtct atgctaagaa aaaagagaat tttgggttta tttcgacctg ttgaattaat
     7861 tttcctagga ttattgttga gtttagttgt ttcgtacctt gcgtggacca atagttttgc
     7921 aacacttcac aatatattag caactgtcgg aatagtggaa cgaagcaaag atcaacagcc
     7981 tcgctatcac attggacaag ctattcaagt acaaaaaagt ggtccatatc atcaatggat
     8041 tggaactatt aataaacagg tagaagatat agccgaaaat taccgagtga gttatcatta
     8101 tgaagtggta tttccaatag gaaaagtcac tgtttctttg ccagaacata acctgaaaaa
     8161 gcctgataaa ccgaggttta aaaaaggaga tatcgttaaa ttatcttcat taactaaaaa
     8221 gccacatata aaagtgtatc aaggtcaatt agcgactatt aaacaagtta aaaaacgcta
     8281 tgactattcg ttaggaggat atcagtacga tattaacctg aaagataatc taagattaga
     8341 tggaatttca gagcaagatt ttgttaaacc ttattatatt aggttcaata aaggaaattc
     8401 ccctgagcaa aacaatcgtc ttttgcgaaa agctttcgct tatgcaaagc agcatccaaa
     8461 tagcgttata tcttttccaa aggggcaatt tcacattggc tctttgcctt cacaaaaaga
     8521 ttattttgag cttccatctg atacagctat tattggtcat cagacagagt tcattattca
     8581 cggtaaaatg ttgtggtttg gattccctac aggaccaaag gctgaacaag gtgttcgtaa
     8641 tctcgtgttg actggagtgc atttcaaagc aaatgatttg aaaaaaggag accactttat
     8701 gattatggct gatcatggta ctgattggca tatttacgat aacaaattta ctatggttca
     8761 taagcgtaat agtcatattt ttgatttagg atctctacaa aattcattgt ttgagaaaaa
     8821 ccaatttatt ggctatgcgc cagaattagt acaagaccaa cagctgctat caaaggctca
     8881 agggcatgat tttttttcag aagtcattca gtttgatgct gctgttcatc attttgcatg
     8941 ggatggaggt ctacttagta atattgctcc aaactatgaa gcatttaacc aaactcgaca
     9001 tctatgtcac aatattactg taagccaaaa tcaattttta ccttatatag atccgactgg
     9061 ttgcctgaga gcctatagtg gttctattgg tcagcattcc tcaaaagtag gagttattag
     9121 ggttttaaat aatgttttta cctcatccat tgttactaaa gcgaagctca ctagttggtt
     9181 tatggaacct attcattttc caccaaattc accggttatt gtcgcaggta atatcattaa
     9241 ttgatgccaa atacctcaat atttacaatt caattttcat caaaaatatg ataaaataga
     9301 tgaataaccg acttgaggag tgtggcatgt taccagctta tataaaaatt catgatgcaa
     9361 ttaaaaaaga cattgatctg ggcatctggc caattggtag tcgcttacca agtgaacgac
     9421 atttagcgga acatttcacc gttagtcgaa tgactctacg gcaggctatt acattactag
     9481 tagaagaagg gattcttgaa aggcggatag gaagtggtac ttatgttgcc agtcatcgtg
     9541 ttcaagaaaa aatgcgagga acaacaagtt tcacagaaat tatacgctcc caaggacgac
     9601 aaccctcctc taaattatta tcctatcaaa agcaattagc tagtgatacc gaagttaaag
     9661 aattgaactt agacaaaaca gacttggtca ttcgaatgga acgtatccgc tatgcagaca
     9721 gtgtcccttt ggtgtacgaa attgcttcaa tcccagaaaa atttataaaa acggttaaac
     9781 gagctgatat tacagaacac ttttttcact cattgatagc aaatggttac gagattggta
     9841 aaagtaaaca gacaatctac gctaagctag caagtgagcg tgtagcctcc tacttggaag
     9901 ttgctaaagg acatgccatt ttggctctaa ctcaggtgtc ttactttaca gacggcaaac
     9961 cttttgagta tgtccgcagt cagtatatcg gtgaccgttt tgaattttac ttagaaaata
    10021 attagtaaag aagtcattta tgacttcctt ttttacacga acagcacaag gcaattaatt
    10081 tgctactgtt aaaaacaatc atagtatgat aaaatgaaca ttatggaaat tgaaaaaaca
    10141 aacaggatga atgccctttt tgaattttat gcagctttgc taacagataa acaaatgaat
    10201 tatattgaac tgtattatgc cgatgattat agcttagctg aaattgctga tgaatttggt
    10261 gtcagtcgtc aggctgtcta tgataatatt aagcgtacgg aaaaaatttt agagacttat
    10321 gagatgaaac ttcatatgta ttcggattat gttgttcgaa gtgaaatctt tgacgacatg
    10381 attgctcact accctcatga tgagtatttg caagaaaaaa tttccattct aaccagtatt
    10441 gataatagag agtaagagga gttttgacta tggcttttga aagcttaacc caacgtttgc
    10501 aagatgtgtt taaacacatt cgcggtaaaa agaaattatc agaatcagat gtccaagaag
    10561 tgacaaaaga gattcgtcta gctcttttag aagccgatgt cgctttacca gttgttaaaa
    10621 cctttattaa gcgcgtacgt gagcgcgcta ttggccatga gattattgat actcttgatc
    10681 caacacaaca aattcttaag attgttaatg aagaattaac gagtatttta ggctcagaaa
    10741 ccgcagagat tgataaatct tcaaaaattc caactattat catgatggtc ggtttgcaag
    10801 gggctggtaa aacaactttt gcaggaaaac tcgctaataa attaattaaa gaagaaaacg
    10861 cgcgaccact gatgattgct gccgatattt accgtccagc ggccattgat cagttaaaaa
    10921 cactggggca acaaatcaat gtacctgttt ttgatatggg gacagaccac tcagcagtcg
    10981 atattgtcag aaaaggtttg gaacaagctc gtgaaaaccg caatgactat gtcttgattg
    11041 atactgcggg tcgcttgcaa attgatgaaa aactgatgga agagctgcgc gatgtcaagg
    11101 ctttagcaca accaaatgaa attcttttgg ttgtagatag catgattggt caagaagctg
    11161 ccaatgtagc ctacgagttt aatcatcagt tgagcatcac aggggttgtg ttaacaaaga
    11221 ttgatggtga tacccgtgga ggtgcagcgc tatctgtccg tgaaatcact gggaaaccaa
    11281 ttaaatttac aggtattggt gaaaaaatca cagatattga aacatttcac ccagaccgca
    11341 tgtccagtcg gattttggga atgggggatt tgcttaccct cattgaaaaa gctagccagg
    11401 aatatgatga gaaaaaatcc ttagagttag ctgaaaaaat gcgtgagaac acctttgatt
    11461 tcaatgattt tattgaacag ttagatcaag tgcaaaatat ggggcctatg gaagacctct
    11521 tgaaaatgat tccaggaatg gctggtaacc cagctttggc caatatcaaa gttgacgaaa
    11581 accaaattgc tcgcaaacgt gctattgtct cttcaatgac acccgctgaa cgtgaaaatc
    11641 ctgacttact aaacccgagt cgtcgccgtc gtattgcagc tggttccggg aacagctttg
    11701 tagaagttaa taaatttatc aaagacttta accaagccaa aagcatgatg caaggggtta
    11761 tgtcgggcga tatgtctaaa atgatgaaag atatgggtat taaccccaat aatcttccta
    11821 aaaacatgcc tgctggtatg ccagatatgt cttccttaga aggaatgatg ggacaaggtg
    11881 gtatgcctga tttatctggc cttggtggtg atatggatat gagtcaacta tttggtaaag
    11941 ggtttaaagg aaaaattggc caatttgcca tgaaacaggc catgaaacgg caggctaaca
    12001 aactaaaaaa agcaaagaaa aaacgaaaat aaaagagacg aaaattttcg tctctttttg
    12061 atgtgaaatt catttatctt gtatacaaga ttattaaaat tacggaagac cgtgttacat
    12121 accatgatga gttcattatc aatctaactt aaatttctaa gggcctaaaa ttagcgataa
    12181 ttttgccaat aatgcgaggt tcttcgctat agggagcaaa cttatcagaa tattttttat
    12241 ttaaggacac tagacgtaat ccctcatctt cacgaaatac ctttttgata tatgtttgcc
    12301 catcccattc gactgcataa actgctccat cgtaatcaaa actattttgt tttataagaa
    12361 caacttcacc atttaaataa gttggctcca tagaatctcc aaaaacccaa gacgcaaaat
    12421 cgtattctaa ttgttcatcg taaaagacaa catcaaagtt accatcacca aaataggagt
    12481 aaccagtacc agcagataaa ctttcataga cccgataagc atataattgt gatggtttat
    12541 ctatgagatc tttagatttt ttgtctattt gatgatttaa caatcgctct gaatagccaa
    12601 ttactttttc tttattagat attgtcagct ggttataagg cgttagcaat ctatagtttg
    12661 ggtcgaaata atcagatgtc acattgaata gatgcaataa ggcatttaaa tgtttttcat
    12721 ttggtatatt cttacctttt tcccaattag atattgtcat tttattgaca tgcaacaatc
    12781 ttcccaattc tgattgagtt attccctttg ataatcgtgc tgtttttagt tgatgtccag
    12841 aaaacatttg gtagctcctt tagtaaagtt ataactttac taatagtatc aaaaaaataa
    12901 aacgaaagca agtgtaacat ttcctacaat taattcatgt gatagcaata ctgtcaaaaa
    12961 gaggaaacac ctaaaacata gcgactagat tcatgtacta gcaggtctat atctgataaa
    13021 gagttaatta ctttaaagat aaaattatca tttagttctg agctaaacaa atgctgtgcc
    13081 tgaagttact aaaataatga tagtaaatta ttactgaatc taaaagaaga gatttgtctc
    13141 gtgacatctt tccgaaaaac tataattttc ttgaaaaata tttataggtg tgatatactg
    13201 ctcttgtaga aaatgaatgg cataaaatac atgagacaat ttgcgaaaat tcatttttga
    13261 aaaattgtta ttgttaagga attatgatga tatgagacgc gaattattac tagaaaaaat
    13321 tgaaacctac aaggctatca tgccttggta tgttttagat tattaccaat ccaaattagc
    13381 tgttccatac agctttacca ccttatatga gtatttaaaa gaatacaaac gcttttttga
    13441 ttggctgatg gatgctgatt taacgcaggc gccaaagatt gctgatattg acttgagcac
    13501 gcttgagcac cttaccaaga aggatttaga ggcctttgtg ctttatttgc gggaacgacc
    13561 ttctctcaac acctattcca ccaaagaggg tctttctcaa accactatta atcggacctt
    13621 gtctgcccta tcaagccttt acaagtactt gactgaagag gttgaaaatg accaagggga
    13681 gccttatttt tatcggaatg ttatgaaaaa agtgtcaaca aaaaagaaaa aagaaaccct
    13741 ggcttccaga gcggaaaata ttaagcagaa actgttttta ggtgatgaaa ctctagcttt
    13801 cttggattat gtggataagg aatatgagca aaaattgtct aatcgtgcca aatcttcttt
    13861 ccgtaaaaat aaggagaggg atttggctat tattgctcta ctacttgctt ctggtgttcg
    13921 tttgtctgaa gcagtgaatc ttgatttaaa agatgtcaat ctaaatatga tgattatcga
    13981 agttattcgc aaaggcggaa aacgtgattc agtcaatgta gcaggttttg cgaaaggtta
    14041 tttggagtct tatctagctg ttcgtcagag acgttacaag gctgaaaaac aggatcttgc
    14101 tttcttttta acagaatacc gtggcgttcc aaatcgaatg gatgcttcta gtatagaaaa
    14161 gatggttggc aagtactctg aggattttaa aattcgtgtg actcctcaca aattgcgtca
    14221 tacgctagcg acaagactat atgatgctac taaatctcag gtgttagtta gtcatcaatt
    14281 aggccattcc tctactcaag tcacggatct ttatacccat attgtcaatg atgagcaaaa
    14341 aaatgcttta gataaccttt aatgttacat aattgttttt atgtaacatt aaagataaaa
    14401 atagcttcaa aattaacttt aatagatggc tactattaac cgtgacagtt tggtgtcggg
    14461 tcgttttcca aactactcaa gtcacttaga aaaaggaata tcactgctaa ctttgtccct
    14521 tctttgaatg acttttttgc gatgtttata gattaaatct agtagggttc tcatcaaaaa
    14581 gatgagataa gcctgttttt agtatgtcag tacttttatt tagtatgata atatgttatc
    14641 ttgtaaagta gct
//
LOCUS       DAUNLR010000042        14164 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUNLR010000042 DAUNLR010000000
VERSION     DAUNLR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14164
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.042"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..1867)
                     /locus_tag="VLL59_001323"
     CDS             complement(<1..1867)
                     /locus_tag="VLL59_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HER6509446.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKSSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTS"
     gene            complement(1864..3609)
                     /locus_tag="VLL59_001324"
     CDS             complement(1864..3609)
                     /locus_tag="VLL59_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HER6509447.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETNDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            complement(3606..4613)
                     /locus_tag="VLL59_001325"
     CDS             complement(3606..4613)
                     /locus_tag="VLL59_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HER6509448.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTVYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEMSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            complement(4638..5843)
                     /locus_tag="VLL59_001326"
     CDS             complement(4638..5843)
                     /locus_tag="VLL59_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509449.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            complement(5843..6646)
                     /locus_tag="VLL59_001327"
     CDS             complement(5843..6646)
                     /locus_tag="VLL59_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509450.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYVVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            complement(6649..7581)
                     /locus_tag="VLL59_001328"
     CDS             complement(6649..7581)
                     /locus_tag="VLL59_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HER6509451.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHNSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            complement(7571..8725)
                     /locus_tag="VLL59_001329"
     CDS             complement(7571..8725)
                     /locus_tag="VLL59_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HER6509452.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDISEKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWTK
                     QKGQLAELINQVDAGFDSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            complement(8844..9698)
                     /gene="rfbD"
                     /locus_tag="VLL59_001330"
     CDS             complement(8844..9698)
                     /gene="rfbD"
                     /locus_tag="VLL59_001330"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HER6509453.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            complement(9837..10175)
                     /locus_tag="VLL59_001331"
     CDS             complement(9837..10175)
                     /locus_tag="VLL59_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HER6509454.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            complement(10411..11520)
                     /gene="rpoD"
                     /locus_tag="VLL59_001332"
     CDS             complement(10411..11520)
                     /gene="rpoD"
                     /locus_tag="VLL59_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HER6509455.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(11529..13343)
                     /gene="dnaG"
                     /locus_tag="VLL59_001333"
     CDS             complement(11529..13343)
                     /gene="dnaG"
                     /locus_tag="VLL59_001333"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HER6509456.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPIPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     EILYQRLKQQGYITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            13474..13836
                     /gene="mscL"
                     /locus_tag="VLL59_001334"
     CDS             13474..13836
                     /gene="mscL"
                     /locus_tag="VLL59_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HER6509457.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            complement(13964..14140)
                     /locus_tag="VLL59_001335"
     CDS             complement(13964..14140)
                     /locus_tag="VLL59_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HER6509458.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
BASE COUNT         4423 a         2724 c         2327 g         4690 t
ORIGIN      
        1 cgctagtcaa taaaccgaca ttttcaatgt tcttaaactt atccttagaa cccgatagag
       61 ctaagaattt ggaaaaacct aaattactat aaactgtttt tctattaaaa ttgttagcac
      121 tagcaggatg catcgcaata cgattttttc cttggtaaaa ctcactaatc gtatgaggtt
      181 tggccatttt aggaaagact tctgaataaa gaacagatac tgaagaagaa aaattataaa
      241 aaggtaagct tgttaacgtt tgaaactcca tgttagcagt tccacccccg taggagtctg
      301 actgcatgag tcccgcagtt gtgctatttt tgattgcctt gatattaggt aaaacatcgt
      361 ggctaacagt aacatttgat actctatcag gatctgacaa gctttcactt aaaagataaa
      421 taaccgtttg gtcagcaata ttattttttc tgtctttatt aatatcttct gctaattttt
      481 ggtacttctg agcgatactc gctattgttt cttgactata atttgtcggt ttttccatta
      541 ttttcttggt cacctgtctt gtccaaacat atgctaaaga tttgtaccta gcatttgttg
      601 aaaaacctaa ccagtttata tcattatcat tatttaaagc cgaaataatc ggaagaccag
      661 ataatatttt accttctttt tcataagaaa atggtattaa catactacaa gatacaataa
      721 ataaacctaa tacagcactt gcccgtttga cagggctcat aaataatttc cctgctaaaa
      781 ctcggccatg tagataccaa gccaccacaa tacaaatagc aagtcctaca accatttcta
      841 caatcaccga ttttttaaca aagcttgtca ctaaacctaa ttcttgtaac caaacaaaat
      901 cagttactaa taacggctcg cttctcattg attcttttaa atcattaaca acagaaataa
      961 ttgttcccag aataagcaaa aagaaggtag ttggccaata tctattcgtt atcacgtatg
     1021 ctaaaagagc aactagtgta atagctacta tctgaaaaag agtagctcca gggaaaacat
     1081 aatatcctag caatgcttca tcacctttta ctccatactg gaacgtatag ttaaaaacta
     1141 atgctaaaaa caaactagta gtagctgcta ctgaaaatga agatttattt gacttaaggt
     1201 gttttagagc atttaaaacc acgtatatga ttgttgcaaa tatgacaagt aaaactatca
     1261 acagtccact tatttttaac agtgcaattt ggctattacc tgctgttact aattcagaaa
     1321 atcgagaact tattagtttt aacagatgta tgtcattaat tggcacaact gctaaaatca
     1381 gagctacaga aaaagtatta ccttgatagc ctaatagccc aaatctatct ttttctattg
     1441 caaaatatgc taccaatatt tttattaaag tggccatcac taaaataatg agtaaagaag
     1501 gtagagcttg aaattgataa aattgatttt tagttaatga ccagatatca aaccgtttat
     1561 cattcaggtg ctgtgttatt tgtacccaat agctgacaat tagataagat atcacaataa
     1621 aactagtttt caaaaacaac tgtcgactaa cttggcgact caaataataa gataatccaa
     1681 tcagtgatat aatatatccc acaaaagaaa catttagtaa atgagtataa tagtttaccg
     1741 gttgtgccgt ggagcttact agttctttcg ccaaactgta aaaactgaaa taaaaaccga
     1801 aaacaagaag gataatatga tgactaatat ttaaccaatt ggtttttaaa aatgtgtctt
     1861 taatcattta agtttctcca ttaaacgcaa gaatatatac ttcattgctt tagcgggacc
     1921 aacaataata tattttaatg ctcctttgat accgcccatt tgattaaagt taacgtaggt
     1981 atgggctcct tcatcttcac gtaaatttaa cagtttattg tcaataaaag gtgttaactc
     2041 atagggattt ttaacaatcc taaaatcata agaattcccc cacgctatat agacaagtaa
     2101 ccgctcaatc gcatgtaata tagagttttg tggtaaaggt tcacttggaa tatcattttg
     2161 agttaattct aaatcaaaaa gtgattttag agcatcgtat ttaaaccata caaatgttcc
     2221 ataactcata acaaatgtat ccatagcttg aaaatcaatt tgttttttaa catccatttt
     2281 tctccacaaa gacatcattt cttgagcgat taaatgctca ttccaagcat tgacaatctt
     2341 attaaatcta aaaaaacttg gaatatctgc gattataata ccaatatcat ttgtctcaaa
     2401 agcgctaaga atactatctg ctggtttcac gagcatatca atcaattctt ttcgccaaga
     2461 ttctcctgcc caaaaatcag cttcttttga ttttttcgta tggaaatgac caatataatc
     2521 atattgagaa agtttatctt ttagtaataa cattggataa atatctcttc ctctatttcc
     2581 cgtaacgcgt atatcagcag ttttaccttt tctttgaagt atttctttga tctcttttct
     2641 tttgatatca ctatctgttg taataaaaag atcataatgg aagttccagt cttcaaaagc
     2701 tgttaaaaat tcatctagca aatcaacgta aaaaacatgt aaatgaacag ctaccttttg
     2761 acaagtttgt tttgctaacc gttggcagtt taggtatttt tgagataaaa ggtacttagc
     2821 atctggcaaa gagatttgcg acatatgtga aacaataaga tctataggat aattggttgt
     2881 ttctcgtatc agattcaata agtaaggagc gatatgctgg ttagcatcaa tagcttttac
     2941 ttttataaaa ggcacatggt gttttaaaat tgctgttgga ttataatatg aaaaatccgg
     3001 atgtggcatg aatgacgact cagcttttct agtatcaaag accgtctgat aactaaagcc
     3061 ttcatttaag agaatggatg ttaattgcgt ttcataatgc tgaatcactt cttgaacgtt
     3121 ttcatattct attatcgatt gccaaaattg ttgaaaaact ttgttttgaa tgacttgatt
     3181 tttaaacgtc ataaaataac tttggacatg ttctttaaaa gcttttgtac ctctattatt
     3241 agtaattccc caaaagtcaa ctgtctcttt ttcttcaaaa ttttcaaaat aaggagccat
     3301 ctcccaaata ggaccaaaac aagtatcgtt cataatcgtc aatgagtcaa actcttccaa
     3361 cttgtcaaat cccatagtaa tcaagccatc gtgccatgca gaaaaatcaa aacctttatt
     3421 tttgcgttgc aaaaactcat caataagaca gtggtttttg agacgtttta aatcttcgtg
     3481 actcacttta ctatttgaga taaaaacaat cttagaaaac agtgatctca tttgttccaa
     3541 ttgatagtaa acatgtgcac ttattttatt gtatttgttg aagtgaacat ataataaaat
     3601 acgattcatt tttttctcct aataaaagca atgagcttag acgtgtattt ccattgacgt
     3661 gaattaataa tggcatggta ttgttgtctt aattcagata gttgattttt ttgttcttct
     3721 atgacatttt gcaactccac ttcacgtgtt tcttgctgct ttgttttatc tacgatagtt
     3781 tgttgtaatt cttgaataaa gcaactcaac tcatgaattc gtatttcttg cttagcatct
     3841 tgttgtaata atagttcaga catttctttt gtatctacct gattatactt ttttaagtaa
     3901 tttaactgag tatcaagtag tttttgaata cgatgaatca tttttggtgt atcagtaggt
     3961 cttgaatcag aatcggttgt catgcgataa accgtcgttg agtctttaat ataggtcagt
     4021 tgagtcagtt gaaataactc tagttgaatg tcaaaagtat cgtctggtgt atctacattg
     4081 attttttggt ttacttgtct cattaaatca gcatcaacta accatgtcga tgccatcgtc
     4141 atccctttta aggctaaaac tttttcgtaa gtatctgtca aaggtgtatg accagatgaa
     4201 aaagcattag catataataa gtcgccttga ctatttacaa agtcaaaatc agtattacac
     4261 catcgtgacc gtttggaagc ttctaagaca tcaacttgtt tttggagttt aaaactatcc
     4321 gtccagtaat catcaccatc acatctagca atatatttgc cttttgcata aaggcatgct
     4381 tttatccaag tctttgttat tccaatatta gtttcgttaa agagtaattt aatttttcct
     4441 gaagactttt tttgataact ctttaaaatc tctcgtgagt catctgtaga agcatcatca
     4501 ataacaataa tttcaacctc aaaatctgtc acttggctta aaaaactgtc aagtgcatca
     4561 gatatccaag gagctttgtt ataattggtg caaataattg aaactttata cataaattcc
     4621 cttctagcta ttactcatta atgaaaaacc cacttcccat tacgttgata caagccactt
     4681 gctgaatcta gagctgacag atcatcttga tcaatatcgt ttctttgaat cactatctgg
     4741 ggtgattgtt ctgctgttga aaagagtagc atctgaccgt tcttatctcg gacagttact
     4801 tctaatttta gttttatatc attaagttga gatagttgac attggtagga aatgcatttt
     4861 ctacctatac cttgtgttgg ataatctaaa gaattgtcgt tgtaaaccca aatgtttcta
     4921 tcaatatccg ttaaagaaaa ggcaatgtag gtaaaatcat cttttaaaac ttcataagaa
     4981 acttcaaatg tgattgtgtc atttggtgtt attcttggat ttgagattaa tgacactttc
     5041 aaatctttgg caatatcaga tacagatatt ttttcagcat tcattgcatc ctcagctgtc
     5101 tctgtattat ctacactata ctgattagca acatcaaatg gttctccata tgctttaaca
     5161 agaccatctt caataagaac tgcacggtta caatacttct taacagctcc catatcatgt
     5221 gtcactaaaa tagtcgtctt accactgtct tttctttcca taaaataatc attacatttt
     5281 cgctgaaaag cttcatctcc tacagcaagc acctcatcta aaataagaac gtcaccttgg
     5341 gctttaatag ccactgaaaa tgctaaacgt acctgcatgc cagaagaata attttttaat
     5401 ttttgattca taaaatgatg caactctgca aaatcaacaa tatcattgta catatcatca
     5461 acttcgtctt tggtaaatcc cagcatggcg ccgttcatat agacgttttc tcgtcctgtt
     5521 aattctggat tgaatcccac tccaagctct ataaaagaaa ccatcttccc atctactgta
     5581 acctgtcctt tttctggaac atagatctgg gaaataattt taaggagcgt tgattttccc
     5641 gagccgttac gcccaacaat tccaaaaaaa tcgcctttat aaacatcaaa gttaatatct
     5701 tttagcacat gttgttcagt aaatccttta atccctctta ggcgattaac cagagtcgtg
     5761 cgaaaacttt tagttgcttc tgtaggcagt ttaaatgttt tactaacatg ctgtactttt
     5821 actgcaattt ctctattaat cattaaataa tctccgcaaa tctatcggca tttttcttaa
     5881 agacaaagat gccaataaat aatataacaa atggtactaa atatggaata acaacgtaaa
     5941 accaattggt tgacatctgc caaatcgtta cgttggctct gtcaatcaat aaataacgaa
     6001 aatcttgaat catttgtgct actggattta gcatcaacaa ctttgccgcc aaagggtggc
     6061 tatctaaaac aaaagtgatc ggataaatga ttggagtggc atacatacct gcttgtaata
     6121 gtacttccca gacttgagct aagtcacgat aataaacaaa gacattcgac aataacaatg
     6181 caattccaag cactaaaaca actaattcta taaaaagaaa aagagagaga taagcatacc
     6241 ctgatatagt cacaccattt atcaacgcaa aaattaaaac aacaaccaaa ttaataagaa
     6301 aattaattaa agctcctaac actgccgaaa aaacaatgat gtgcttagaa aagttcaatt
     6361 ttcgcaacaa gtctccccga gatacaatag ataccattcc catgctagtt gcttctgaaa
     6421 aaaaagacca gatgacattt gccaataaaa gcgctactgg aaaatgaggt acatttccac
     6481 ccaggcgaag aaaacgaata aataccaagt acataatcgt aaacatcata agcggtttta
     6541 agatagacca tagatagcca attgcgctcc cttgatagcg taatttaaaa tccgttttta
     6601 ccatttctct cagtaaaata cggtttttct ttgttaaaaa attcattctt actttctcct
     6661 gtaaccaaat aaggtaacaa ctaaactacg aaaaataaag gtgtgaaaga tgcgattttt
     6721 tctaaaaccg taccttttca aggtagctaa gcgtttggta aaaggcatat ccaataaaga
     6781 aacataggcc gttaccaatt catggtcatt tggttttaat ggtaaatcta atagtaattg
     6841 agcctgtttt tggcttgaag taatcaacca ccaatatttg ttgactaaat gatggggggt
     6901 taaccaattt ttcatgcgtt tagaccaagt tctagctccc aacacgttag catcgtgctg
     6961 acggtataat tctgttggaa tatcaaggta aactaatttc ccagtagcag aagctagtaa
     7021 agctaaatac cagtcatgca tcaataaacc gtcacaagtg gtccattcct cagccagagc
     7081 atgagtaatc atcattgtgc cgcctgttac ggtattttcg gttaattctt gaagtaggct
     7141 tgtgtttgca tgaccagatt gggtcttaat catactgtta tggcaaatag ctaaatgttg
     7201 ggttaccact ttgaggtctg tataaaccaa taaaggagct gtcatttcat gtttttgagc
     7261 ctccaataag gtcacttcca gtttattgtc taaccatata tcatcttggt cactgaaaaa
     7321 atagacatct gctttttggt gctttaagag ggtgtaaaaa ttcttaataa ctcccagatt
     7381 ttctgtctgc ccctcattga tccactgaat tcgtttgtct tccttgacaa atgtgcgaat
     7441 aatatcctgg gtgccatcag ttgatccatc atctctaatc aataaggtcc agtcgttaac
     7501 tgtttgcctt tggatacttt gaatttgttc tgctaagaag cgttctccat tgtaggtgga
     7561 tagtaaaata ttaatgttca tttaaaaata aagcctcgta ctcccctaca attttttccc
     7621 aagtgtaatg ttcttgaata atagctttgg cttctttgcc cagacgatca ctatcaaaac
     7681 ctgcatcaac ttggttaatc agctctgcta attgcccttt ttgcttggtc caatacagcg
     7741 cagcagactt agccaccgac tggttaaaat caactcctaa aaccaaatta agattggtat
     7801 gggctagtgc ttctagaagg cctggattag tccctcctac ctcatgacca tggatatagg
     7861 cataagcctg ttctcgaatg taggctaata gttctttgtc ataaagggta ccaacaaatt
     7921 taatgcgtgg gtctttatca cactctgtct cagcaagtaa ttgcttaaag taagcattgc
     7981 cttcatgatt acaaataatc actaaatcac gcttagttga ggaagccata aattctttaa
     8041 tagcggtttc gtaattattt tcaggaacaa agcgtcctaa aatgagatag taatcctttt
     8101 cgctaatatc aaaggtttga aaataagctc tgaccttgct atctgctgtt gtcaaacgtg
     8161 aaggttgtgt ctgcgttcca taagcaataa aacatgtttt agaccaagga taaacctgtt
     8221 taaggtagcg gtcaatgcca atattatctg aaatgaccaa atcagcctgt ctagtcattt
     8281 gcttttcgga aaacttcagg taggcctgca ctggttttga ccatttagac cgtttccact
     8341 ctaacccgtc tggattgata aaaaagcgtc cacctcgatt gtgaatctgc ttcacaaatg
     8401 gcgcaataaa agcgcctaca gtattgccca acacataaaa aatagggttc tgaatctggt
     8461 gttggtcgct ataagacagg gcataggtaa ttgccatcat atcataagca ataactctag
     8521 caggaccaag ttttggggga ttaaggtaaa agcaatctgc ccccttataa tcaaaatgaa
     8581 ccttatgctt cgtatcgctt aaacaagcaa cgtgataacg aatgttttta gatgattgat
     8641 gactaatcaa ctcttcgaca aaggtttcaa agccaccgta tttcgctggt aaccctctgc
     8701 taccaatgat aaaaacatcc tgcattgcat actaccccat tctaaaatat aatcagtgat
     8761 attataccac aattagaagg ctaatgcgac cttaaaccca tgaaaaagag ttggccttag
     8821 aaagccaact ctttttagaa tacttacttt ttcagtcctt gttggtaaaa tgccttcaag
     8881 gcttcttgcc atgttggaat aacaaaccct gttgcttttg ccttatcaag attcatggtt
     8941 gaatttaaag gacgtttggc ttttgctggg aaagctgatg aatcaactgg caccacttca
     9001 acagccttgt cttttaagat ttctttggca aaatcatacc aagtggtgtc ttccttagca
     9061 tcatttgaca agtgatagta accaaaggct ttttgattct ctgtcaaata acacatgaat
     9121 tctgccaagg ttcttgtcca cgttggccga ccgtgttggt cattgacaac agtcaaacgg
     9181 gagtgatttt ctgctaactg ctccatggta aagacaaagt ttttaccata atttccaaat
     9241 acccaagcag tacggataat ataaaaatgc tctgcgtatc gttcaacagc tagttctcct
     9301 aaacgttttg tacggccata ttctgtctta gggtctggac gatctgtttc tacccattct
     9361 tgaccgactg gtttattgcc atcaaatacg tagtctgttg aaatgtaaac aagggtagcc
     9421 ccatattttc cacaagcctt ggcaatattt tctgagcctg ttacattaat agcctcattc
     9481 aaggcttttc cttcgtcttc tgctgcatca actgccgtat aagcagcaca atgatagacc
     9541 aatgttggct tgacctgcgc aaaaacagct tcgactttgt cttcatttgt gatgtccatt
     9601 tctgcgacat caacggctac ataatcaaca cctcgttcat ctaataagta tcgaagttct
     9661 gtccctaatt gaccattgct tcctgtaatt aaaatcatca gttctccttt ttgccatagg
     9721 tagaacactt tttttcagta tcttagtgtt ctctaacatt aactaaaggc tttcacctgt
     9781 atttcctttt attctacatc aaaaaaggga atatttcatc cctttactat caatgattag
     9841 cgaataccca gcgcaatcct agcatagcgg ctcattttat caaccgtcca agcagggtac
     9901 cagactaatt tgacctcagt cttagtgact tctggcacat cttgcagggc atcatggatg
     9961 taatctgtca acaagtctgc caaaggacaa cccattgttg tgagtgtcat atcaatctct
    10021 gtataaccgt tatcattaaa ccgaatttca taaatcaagc ctagattaac aacatcaata
    10081 cctagctcgg gatcaataac agtttctaaa gcttcaagaa ttctattctt gatagctatc
    10141 acctgatctt gtgtatattt tggtgtatca gacatggctt tcctttcatt ttttgaatat
    10201 gtcgtagata agtaaaaaaa ccactaaagc tttgcctatt tagaggaatt gccctctggg
    10261 cttgtttaag atatcaagtc tacccttaaa aatacccacc acattcggtc cgttttctaa
    10321 tttgtaggtg taccgctgat aagtgccact tgggattttc gctcctttct tatttcaaag
    10381 gaacgaccta aaatcgtcca ctggacgatt ttagtcctct ataaagtctc ttaattgttt
    10441 actacgacta ggatggcgaa gttttctaag ggctttagct tcaatctgtc gaatgcgctc
    10501 acgagtaaca ttaaagactt tacctacgtc ctctaacgta cgcattttac catcgtcaag
    10561 gccaaagcgt aggcgaagaa cgttctcttc acggtcagta agcgtatcta aaacttcatc
    10621 caattgctca cgaagaacaa cacgcgtcgt ataatctact ggattttcaa taacttcatc
    10681 ttcgataaaa tcacctaagt gactatcatc ttcttcccca attggtgttt ctaaagaaac
    10741 aggttcttga gcaattttta gaatttcacg aaccttgtct ggagtcatgt ccatacgttc
    10801 tgcgatttgt tctggcgttg gatcttgacc aagttcttga agaaggttac gttgttcacg
    10861 gactaatttg ttaatcgttt caaccatatg aacagggata cgaatcgtac gtgcttgatc
    10921 tgcaattgcg cgtgttatag cttgacgaat ccaccatgtt gcataagttg agaatttgaa
    10981 tccttttgaa taatcaaatt tatcaacagc tttcatgagt cccatgttac cttcttgaat
    11041 taaatcaaga aattgcattc cacgtccaac ataacgtttt gcaattgaga caacaagacg
    11101 aaggtttgct tccgctaaac gttgtttagc cattagatct cccttggcaa ctgcaacagc
    11161 caattctttt tcctcttcac ttgttaaaag cggtaccaca ccaatttctt tgaggtacat
    11221 gcggacagga tcgtttactt tagctgaatt actaccaatt aattcttcat cagttaattc
    11281 ttctggtttt ggttcttcaa caatgtattt tgatgatggg ttaccttctt tatccgtaat
    11341 cgagatacca ccatctgtta accgctcaag taaatcatca atctgatcag catccaaagc
    11401 aaatggaatg acaagttttt cggtcacgtc atcatcaatc gctgttcctt cttttttgtg
    11461 atggcgaata aactccgcaa cttgaacgtt aaaagttgtt atttcttttt gttttgtcat
    11521 aatttcctct attccatttt tcgtttctgc gcaataaaat gttctagtac ttctagagcc
    11581 gcttgatgat cgcctttgtt actagattct ctaacttttt tcccttgttt gtgaagatcg
    11641 cgctctgcta aaagtttggc acgtttggat aaaatatcat caatctcacc aagagctact
    11701 tctttgggaa ggttttcttc taaaacattg taataagcac ggttaacttc ctctgacatc
    11761 tctgacaaat cataagatgt aatgtatcct tgttgcttca accgttgata aagtatttct
    11821 aaggtagagg tatcaaaata aaaatcatca cgatgtcgaa attcatttaa taaatagtca
    11881 tgatgtaaga gccgatgcat gagatgactt tctgtcttag caatagctgt caaacttttt
    11941 ggtattggta aggtcacaag attgctgacg gcttgagcta tttgaccttg acgcttttgc
    12001 ctatcttgaa tccttaatgc atttactgat tgttctactt gaaaatagtc aaagtttggc
    12061 aacaaatcag caatcttgtt aatatacgaa tgttgagctg tgatggatgg tgattgagca
    12121 atcaatggcg ccattttctc cacataaaca atttgtgatt gcaaattgtc tacattagta
    12181 ggttttaggt aatcaataaa aaattcaaca ctactgatcc gtgactgctt aagcaaatct
    12241 gcaaatgctt ctggggaatg ccgttgtaca aattcgtcag gatccatttt attggggatt
    12301 ctgacaattt cgacaacaaa atctttaagc aattctagtg attttgcaat agcatgttgt
    12361 ccagcatcgt caccatcata aatcaaaaca acttttttag tgacttgctt aaggtgattg
    12421 acatgttctt gagtcaatgc cgtccccatt gaagcaacag cattttcata gccggaacgg
    12481 taagcggcaa tcacgtccat aaacccttcc attagaaaca cttcatgggt tttggcaata
    12541 acaggccttg ctttgtccag atgatacaat tcataagatt tgttaaaaag aactgttcct
    12601 cttgaatttt tatacttggc ctgtctcttt tccatatcag ctgccgtcca gatacgtcct
    12661 gaaaaggcaa taatatgccc tcggtcatct gataagggaa acatgatacg atttcgaaag
    12721 gcgtcgtaaa tggtattgga ttgatcggac aagttaaaca atcctgaagc aaccaattga
    12781 ccttcctcgt attttttaga aagagcttga taaagataat ctgactcatc tggggctaaa
    12841 ccaatattga aatgctcaat taattggtca tccaagcctc tctggtaaag gtacttccta
    12901 gcttcttgac caatggtagt ggtcatcaaa actgcatggt aaaatttagc agcatcctca
    12961 tgaagtgtca tcaaagcgtg attagggtgc ttgtgttggc tagcaagtac tgcctgactt
    13021 ggcggtatat taagcgacat accagtctta tcggcaataa tctgaacact ttctaagaag
    13081 gggacttggc ggtattcctc aataaattta aaaacatccc ctgattttcc acagccaaag
    13141 cagtgaaaaa attgtctgtc ttcaacaaca ttaaaagagg gtgtcttttc cttatgaaat
    13201 gggcaaagcc cgagataatg ccgccctgat cgggaaagtt tgaccacttc tccaatgaca
    13261 tcgacaatat taacgctatt ttttacttgg gaaatcattt ctttgtcaat tgccaaatcg
    13321 tcacctcccc ataaaaatcc cattttagtt ttacgtttta ttataccacc gaaactcttt
    13381 tttgtaaatt taaaaactga agtgattcca ttggattttg tttactaatt atgctatgct
    13441 taacttagag atattaaaaa gggggaatgt ttaatggtta aagaattaaa agcatttttg
    13501 tttagaggaa acattattga acttgctgta gcagttatca tcgggggagc ttttggtgct
    13561 attgtcactt cttttgtgaa cgatattatc acaccgctta ttttaaaccc agctttgaaa
    13621 gctgcaaatg ttgaaaacat cactcaattg tcatggaatg gtgttaaata tggtagcttt
    13681 ttaggagccg ttattaattt tcttatcatc ggtaccagtc ttttctttgt tgtaaaagcc
    13741 gctgaaaaag ctatgcctaa aaaagaaaaa gaagctgcag ctcctactca agaagaatta
    13801 ttgacagaaa tccgtgattt gttggctcaa aaataaggcg atttttgata aagtagttag
    13861 gcatgtctaa ctgctttttt tgatatcaaa aaagctccct tgcttcttct ggataaaaaa
    13921 taaaaacagt tctaattgtg agaactgttt ttatttttta ccattagaat tttttacgtt
    13981 tgcgagctgc ttctgattta cgtttacgtt ttacagaagg tttttcgtag aattcacgtt
    14041 tacgtgattc ttgaagagta ccagctttag taacagaacg tttgaagcga cgaagagcat
    14101 cgtcaagaga ttcattctta cgtactactg tttttgacat gtgtttcacc tcctcaagat
    14161 attg
//
LOCUS       DAUNLR010000043        14104 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUNLR010000043 DAUNLR010000000
VERSION     DAUNLR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14104
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.043"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            1..2002
                     /locus_tag="VLL59_001336"
                     /pseudo
     CDS             1..2002
                     /locus_tag="VLL59_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018223.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
     gene            1999..2736
                     /locus_tag="VLL59_001337"
     CDS             1999..2736
                     /locus_tag="VLL59_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509459.1"
                     /translation="MNQLLLKNVCKRYPNQPNYALDHINLTVRKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISAFSDNEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNVDSSKINDLINNYAKRFNLYEQLEKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEGTMRILSEINKTEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHMEIDKEDCGETFYDVISQALSDRGE"
     gene            2738..4645
                     /locus_tag="VLL59_001338"
     CDS             2738..4645
                     /locus_tag="VLL59_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HER6509460.1"
                     /translation="MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIIT
                     EKIGDSGQALVIANGSLVFLTVFLVIFLIYFNNFFVKKRSQELGVLAILGFSKKELTQ
                     LLTLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITVNEIIESLGIL
                     VVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLAT
                     VFSSTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKENKKRLYRPLSNI
                     IYPKFNYRIATKNKLLTVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVES
                     ENGQVNVTTILENDQVSLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKA
                     QGRINSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTL
                     VVSDKLYAKLSSCFPEKEMTIRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTA
                     NIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYE
                     TGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVL
                     TLRSVTSIIKN"
     gene            4685..6247
                     /locus_tag="VLL59_001339"
     CDS             4685..6247
                     /locus_tag="VLL59_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HER6509461.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNVILYGHKQFKDKLDKGLLIIIFVSITSLFVNRILFNFLFLIVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSEFYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWVVLIKVLVKDFL
                     LFFIIVDASTLFGLVVISCIFYYLENSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     DVLQNIIAIKNLLSLENSNITRGFIVNELNDLVSGIREEIDTYHPIVPANQTMKENIQ
                     SLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSL
                     TIQSDIIIIEESNQVVEKVHSINYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLP
                     IDWKLCYEDFIN"
     gene            6228..6833
                     /locus_tag="VLL59_001340"
     CDS             6228..6833
                     /locus_tag="VLL59_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6509462.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(7387..8967)
                     /locus_tag="VLL59_001341"
     CDS             complement(7387..8967)
                     /locus_tag="VLL59_001341"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HER6509463.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLIAVCDNLEEHFNTFTDAQKIFEDAYQDEELKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFSDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDCNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(8980..9579)
                     /locus_tag="VLL59_001342"
     CDS             complement(8980..9579)
                     /locus_tag="VLL59_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HER6509464.1"
                     /translation="MTKSKQPQYRFDGFEGEWEEKKLGEISRMFSGGTPNVGIPEYYN
                     GNIPFIRSAEINSDQTELSITDKGLSNSSAKLVEKNTLLYALYGATSGEVGLSRISGA
                     INQAILAIIPEKKYSSLFIKNWLYKQKSSIIEKYLQGGQGNLSGSIVKELTIHFPSLS
                     EQEAIGNFFQTLDQQIAQSEEKLTELKALKQTLLNRLFV"
     gene            complement(9592..12570)
                     /locus_tag="VLL59_001343"
     CDS             complement(9592..12570)
                     /locus_tag="VLL59_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HER6509465.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKETLSIPRAHQMVITYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKDRLAHLNVV
                     FVVDECHRAVTPERQRYLTNTFRNSLWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLDSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLMKKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSVTENDNASISRQYKMAENLEDYNSLFGTNFTIDNLQGYNRDLNDRLARKRDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFLENVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNSAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            12851..13993
                     /locus_tag="VLL59_001344"
     CDS             12851..13993
                     /locus_tag="VLL59_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HER6509466.1"
                     /translation="MTINRALKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFCQTTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
BASE COUNT         4519 a         2190 c         2613 g         4782 t
ORIGIN      
        1 aaatcagtta tttgaaacta taatgtttct ttcaatgaaa acactagttc tagatataaa
       61 tcatttttcc aaggaaattg aaaataagtc aaaggcatat gaacaatata tacagcagat
      121 aagggaagaa aatgggataa gtaatttttt tgacagatat ccatatttgc taaaacaaat
      181 caatagagaa gtttgattgg tagtggaatc atactctttg ctatttgata ggtttttaaa
      241 agatttgtct gaaataaggt catgctttaa tattactgag tccttaagta atgttgaatt
      301 ttcacttgga gacagtcatt cccaaaaaca aacagtcgtt aagattgaat ttaaagggaa
      361 atccgtttac tacaagccta aaagctatga ttcatacaat atcttgttgg aacttattag
      421 tctattgaaa tctaataata taccttcgtt cagtcttcct gaaagcttaa ttaaagcgga
      481 ttattgttgg caacttggtg tagcttatac aagttccaat aaagatgaag tagcgaaaat
      541 ttactttaag tatggtgttt tagcagcatt ttctgaaata ttttctatta cggacttaca
      601 tatggaaaat gtgattgttt caggcggaga tttatattta attgacgttg aaaccttttt
      661 tcaaagaaag ttgaatgtac aaaatcagaa ttttgaaggg attactgtag acacctatca
      721 gagaatttat gagacatcac tttcaaacgg tttatttcct gtacaatttg agaaaaacag
      781 cgctcctaac gtttctggaa taagtggaaa aggtggaaaa agaaaaaaag gaaaatatga
      841 actgataaat aaaaatcgtg gagatatgaa gttagtaaaa gttgactatt ttcaagaaga
      901 tgggttcaat attcccacat taaatgggaa agtggtagag cctcttgact atgctaatga
      961 gatcatttca ggatttagag agtgctacat atttcttata ccacaacgtt caaagattaa
     1021 agaaatagta gaaggttttc cagaattgaa aagcagagcc ctatttcgaa atacttccga
     1081 ctatggaaaa tttttgcaag cttctacgaa tccaaagtat cttttctcag aaaaaaagag
     1141 gaagaattta ttttcgatac tatatgatgc aaaacatatt gaacatttta ttgttgataa
     1201 tgaaattaaa gatttgatga atggtgatat tccttacttt tcaatggata ccagaggaaa
     1261 cgtctataat tctgtaggga cattaattgg aaatctagga gatacaacct cgttatttga
     1321 tagtataact attttgaacg atgaaagatt gaagttcact tgtgaattgc ttgaaatagt
     1381 cttgaaaaaa ccgattaagc attgggagag ggaaaagggc aaatcttatc agttttatca
     1441 atctcctcag aacattacct tctctaaaat tgataaaact gattttagga atatatcggc
     1501 ttttgcatct caagattctc caatatttga tggggatgtg atgtataaca ttttgctagg
     1561 aagagaatct gttacagaaa aacaagttat tgaaatctgt aaaagggtat cactatatga
     1621 ggatatcagg agtatgccaa tgaagtttca taccccactt tttcgagaca atccatcact
     1681 atctgggggg caaaaacaac gaatttctct agcaagagag ttagtaacta cccctagaat
     1741 cttagttctt gatgaaccta catcagcttt agatgtaaaa actgaaagaa taatccaaaa
     1801 aaatgttgag gctttacatt gtacgagggt tttggttacc catagactta atacagttga
     1861 aaaagctgat aagattttaa taatggataa tgggaaaatt attgactatg gtagtcatca
     1921 ttgtttatat aaaaataatg agtactatcg tgatttatat gattcgtaca tgaacaacta
     1981 tcaggaggaa gagataaaat gaatcaatta ctattgaaaa atgtttgcaa aaggtatcca
     2041 aaccaaccga attatgcttt agaccatatc aatttgactg ttagaaaagg agaatttgta
     2101 gctgtcatgg gacgtagtgg tagtggaaaa acaacacttt taaatgttac ttcaattatt
     2161 gataaaattg atagtgggag tatttattgt gcagacaaag aaattagtgc attttctgat
     2221 aacgaggcaa ctagttttag aaaaaatgat attggttttg tttttcaaga ttatatgctg
     2281 ttagacagtc taaccattag ggagaatatt tctgttgctc tatctttaaa aaatgttgat
     2341 tcatcaaaaa ttaatgattt gataaataac tatgcaaaaa gatttaattt atatgagcag
     2401 ttggaaaaat atccgtatca actttctgga ggtcaaagac agagggtcag tattatcaga
     2461 gcaatcatta aagaaccaga gattattttt gctgacgaac caactggagc acttgactta
     2521 aaatcttctg aaggaacaat gaggattttg agtgaaatca ataaaacaga aaaggtaact
     2581 attttaatgg ttactcatga cgttttatca gcttcttatg cggatagagt tgtacttctc
     2641 aaagatggta aacttcacat ggagattgat aaagaggatt gtggagagac gttttatgat
     2701 gtaattagtc aagccttatc cgatagagga gagtaatatg atttggtcca ttacaaaatc
     2761 taacatcaaa aaaaactttt cgttatatcg tatctatttt ctagctacga ttggtttatt
     2821 aagtattttt atagcttttc taaattttat ctcagataaa atcattacag aaaaaattgg
     2881 ggatagtggt caagctctag ttattgctaa cggatcatta gtttttttga ctgtattttt
     2941 ggtgatattt ttaatttatt tcaataattt ctttgttaaa aaacgtagtc aagaacttgg
     3001 agtcttagca atactagggt tttcaaaaaa agaattaaca caattactga ctttagaaaa
     3061 tcttgttatt ctagttttaa gttacttggt aagtttacta ttgggaccga ccttatattt
     3121 tttagcggta ctggtaatta ctcatctatt ggaattaaca ttggaagttc agtggtttat
     3181 tacagttaat gagattatag agtctttagg aatattagtc gtagtttttc tgattaatgt
     3241 catcacaaat ggacttatca ttagtaaaca gtctttgatt gaatttgtta atttctcaag
     3301 aaaggctgag aaaaaaatta agataagaaa agtcagagct attattgcta tcactgcatt
     3361 gctattgtca tatattttat gtttggcgac agtgttttca tccacacgaa atatgctatt
     3421 aagcataggg atggtaccgg tttctctatt gataattgtc ttagttgttt taggaacagt
     3481 gttcaccatc agatatggat tggcttttgt agtttcgttg ttaaaagaaa ataaaaaaag
     3541 gttataccgt cctctgtcta atatcatcta tcccaaattt aactatcgta ttgcaacaaa
     3601 aaataaatta ttaacagtct tgggaggtct tttaacagta accgtttcag ttgccggaat
     3661 gatggtaatg ctctatgctt attctcttaa tgggatagag aggttgactc catctgccat
     3721 agaatataat gttgaatcag aaaacggtca agtcaatgtt acaactattt tagagaacga
     3781 ccaagtgagc ttggttgatg ttgacctatt gagattgaac actaacccag aagtaactat
     3841 cacagaatct gggcaaacaa ttccttattt tgatataatt aattacagtg attataaaga
     3901 gttaatgaaa gctcaaggga gaataaattc tattgaaggt agtaagtcac tcccattgtt
     3961 aataaattat tatccaacag aaattagcct tggaaaaacc tttaacttag gaaatgcata
     4021 tgatgttact gtaaaacaag tatcaacgca taatgttttt agtttttcta caagtgtcac
     4081 gaccttggtt gtttctgata aattatatgc taaacttagt tcttgttttc cagagaaaga
     4141 aatgacaatt aggactttta atggaaattc gattaggtca agtgaagcat tttacaatca
     4201 gtttagtatg gttcctgatg ttatcagtag ttatagtaag gaatacacag taaagactgc
     4261 taatattgcg acttatatct ttataacttt cctatccata ctctttatta tttgtacagg
     4321 tagtattctg tactttacaa gcctcatcga aatcatggaa aataaagaag aatatggcta
     4381 tctaagtaag ctaggttata gtaaaaaaat gattcatcgg attcttcgat atgaaacagg
     4441 tatacttttc cttattcctg tattcattgg gattgtaaat ggtggtatgt tgcttattta
     4501 ctataaatat ttattcatgg atacattggt agcaggcaat atcataatgt tatctttatt
     4561 gctttgtctg cttttcttct tgataatata tggcacattt tatgtattga cattgcggtc
     4621 agtgacatcc ataatcaaaa attaatttta aaaatctttt aactttaacg attaagtaaa
     4681 taatatgata agaataaaaa acataacaaa gagtaagttc tttgggactg caataatctt
     4741 gttgcaacaa ttaatagcct tgttaatttt ggtctataat cgagagaacc tgtctcttct
     4801 tttctctgaa aaagtagctc ttgtaatgac ccttattgat acagctttta tttggctggc
     4861 aacaatatta cgccaaaaac aaggtgatat ttttaaaagg attatttcta tcatctcctt
     4921 aacaatttgg caatacttag tatctgtgct gacaagagga actcctctct ttttaagcag
     4981 tggactacag attatattgc tctattgtta taccgttgag attactaatg taatattata
     5041 tgggcacaaa caatttaaag ataagttaga taagggcttg ttaataatta tttttgtttc
     5101 tataactagc ctttttgtta atagaatttt atttaatttt ttattcctga ttgtttttac
     5161 tattttacac ctgtatccgt tactagttat agtgctatat tataggtctt ttaggcaaca
     5221 aatatcagtc gttagacgtt cattgatact attttcttta cttttgctgg taatacttgg
     5281 tagtgaattt tatggagaaa tgctagatgt taatcaagcc tttaataatt tgggatggta
     5341 tctgtttccc cttataatga gtgtaatata ctattttaag accatacatg ataaattgag
     5401 ttttgttacc caaagatggt taggtgatta caaagctcgt atagaactat tatttctact
     5461 tcttatcctt tgttgggttg tactcataaa ggtactagtt aaagattttt tattattttt
     5521 tataattgtt gacgcaagca cgttatttgg tctagtggta atttcttgca tcttttatta
     5581 tttagaaaac tctaaacaaa attttgacta tgaaaataga agactgaact attttatgaa
     5641 atcagaggaa aacatgagag tggagttctc aaattatttg catgatgatg ttttacaaaa
     5701 tatcatagcg ataaaaaact tgctttctct agaaaatagt aatataacac gtggttttat
     5761 tgttaatgag ttgaatgatt tagtttctgg tatcagagaa gaaattgata cttaccaccc
     5821 aatagttccc gctaatcaaa caatgaaaga aaacatacag tctctttttg atgatattgt
     5881 taaaagtaga aaaagtaata ccttattgta ttttaactgt tcagataata tggtagtgcc
     5941 atccccatat ggagatattg tttataggtt tataaaagag ctaataaaca atgctataaa
     6001 atatggagat ggaaaagaca ttcgtttatc tttaacgatt caatctgata ttattatcat
     6061 tgaggagagc aatcaagtag tggaaaaagt acactctata aattatggca gaggattgaa
     6121 atcatttcaa gaaacactag cagcttttga tggagatcta gaactacaaa tggatactaa
     6181 acaatttact atcagaatat tacttcccat agattggaaa ttgtgttatg aagattttat
     6241 taattgatga ccacagacta tttgcaaaaa gtatccaact gttattccaa cagtatgatg
     6301 aagtagatgt catagatacg attacttctc attttaacga tgtgacgatt gatttgtcta
     6361 agtacgatat tatattgctt gatattaatt taacaaatat ttctaaagaa aatggattgg
     6421 agatagcaaa agaactcata cagtctactc ctcatttgaa agttgttatg ttgacaggat
     6481 atgttaaatc aatctataga gagagggcaa aaaaagtagg agcatacggt tttgtagata
     6541 aaaatataga ccctaaacaa ctcatttcta tcttaaaaaa agtggattct ggaaaaaagt
     6601 attttgaaca aatcgaatct caggattatg ttgaatcttt aactgaccag gaaatagcta
     6661 tcttaaattt gagtaagaaa ggattctcta taaaagaaat agaggaaacg ttacaaatta
     6721 gtaggagaac agtatttaat catttgaccc acatctactc aaagcttttg gtaaataaca
     6781 agcaagaggc tatctacaaa gctgaacaat tagggtattt tatggatttc tgagttgcag
     6841 ataatcaaac gacataagtt ttacttgtgt cgttgctagg gatttcctgt taaataccca
     6901 gatttaaact cattgttttt aagttctttt tgattgaaat tgattgagat aacgctttta
     6961 taaaaagtag ggcaatgcct gatatgaaaa gctttttaaa tttagtcaaa caaaagttgt
     7021 ttaaaccagg tctaaaaaaa ctcgtaaagc ttcacaactc ccagaacgtt aatatatgct
     7081 tatatatcaa cgattggaac tactttatgg ttcgcaccat ggggtttttg tggaaggatc
     7141 aaaagttgtc ctgaaaattt ctcttaaccg tgtttaagct ttctaaacgt ttgagaaatc
     7201 attgtaactt caaataacta ttttaaataa aacaaagaaa cggacaaagt tagatgagat
     7261 gattctattt tgatttatag gtgaagaagg agaatcttgt atgataagta ctcaataaag
     7321 gttcactact caattttaaa taaaacgcca cagtagtaat catctactgt ggtgtttttt
     7381 tgtcttttag tttctaaaag tatccaattc gtcttgtgct tctttggttg ttccgactag
     7441 ttgtttcatg agttgatcta gtttggcatt tgttttggca atttcttgat caatgtcact
     7501 gagctgttta gctaattctg gcagtggttt aactgggact tcctcaaagg tatcaacata
     7561 gcgtgggata tttaagttac agtcattttc aatgatttca tcaaatgagg ctaaatatga
     7621 aaacttatca gaattatcac gactcttata agcatcaagg atctttttga tatggctatc
     7681 tgtcattgtg ttttgatttt tacccttatc aaactctttt gaagcatcga taaagaagac
     7741 atctttgttg gttctgttct tctttaatat gataatagtc gtagggatgc ttgtattata
     7801 aaagatattt gatgggagtc cgataatggt atcgatagcc ccttgttcga gtagtttttg
     7861 gcgaatcttg ccttctgcag caccacggaa aagaacacca tgtggtaaga caatcgccat
     7921 ggttcctgta ttttttaaat gatagaaacc atgaagtaaa aaggcaaagt cagcttttga
     7981 ttttggtgct aatacaccat aacttgaaaa ccgtggatct gttaagaaac cagcagtcgc
     8041 tgaccatttc aaagaataag gtgggttcat caacacccca tcaaagttgg ttggttcatc
     8101 tgttggccag tctgcatcca aggtatcagc gttacttaag tgttggtttt cgatggcaac
     8161 gccatgaagc atcatgttca tacgagccaa gttataagta gaagtattga tttcttgacc
     8221 atagtaagaa acggtatcgg attggttact atatttctta gcatttaaaa ggagtgatcc
     8281 agatcccata gcagggtcat agagggtcat tcctttttga tcttcacgac ctaaaaagac
     8341 aatctgagtc atcaagtgag agacagcttg tggggtatag aactcacctg ctttttttcc
     8401 tgactcactg gcaaattcac caatcaagta ctcataagca tcgcctaaag tatccccatc
     8461 tactgcctca aagtcaattt catttaatgt tttcatgaca ttagaaatgg tttgattttg
     8521 tttttgagga gtagagccta attttttaga gtagaggtca atatcttcaa ataagttttc
     8581 aaagtcttca ccactttgtt caatatcgct aaaaccttga gctaatgatt ctaattggaa
     8641 agtattgtga taaacatctt ggatgagttt ttcaaaggtc agtgtcggtt cgataaagta
     8701 acctaaatca ccagtaacaa cagaaatgag gtcatctttt agttcttcat cttgataggc
     8761 atcttcaaag attttttgag catctgtaaa agtattaaag tgttcttcta aattatcaca
     8821 aacagctatg agtaatttat cagataagtg cttgtaaaag atgagtccaa gaagatagtt
     8881 tttatagtca ttggcatcca tttgaccacg taattggtcg gccgaatgcc atagtgcttg
     8941 ccggagtgaa gttgttttct ctgccatgtg agtcctttct tatacgaata aacgattgag
     9001 taatgtttgt ttaagtgctt taagttctgt tagtttttct tcagattgag caatttgttg
     9061 gtctaaagtt tggaagaaat taccaatggc ttcttgttcg gagagagaag ggaaatgaat
     9121 agttaattct ttaacaatag aaccagataa atttccttgg ccaccttgta aatatttctc
     9181 aataattgag gatttttgtt tatataacca attttttata aaaagagaag aatatttttt
     9241 ctcaggaata atggctaaaa ttgcttgatt aatagctcca cttattcttg aaagtccaac
     9301 ctctccacta gttgcaccgt agagagcgta taataatgta tttttttcca ctaattttgc
     9361 tgatgaattt gatagacctt tgtctgtgat agataattct gtttgatcac tgttgatctc
     9421 agcagatcta atgaaaggaa tattaccatt atagtattca gggataccta cgttaggagt
     9481 gccacctgaa aacatccgag atatctcccc caatttcttc tcttcccact ccccttcaaa
     9541 accgtcaaag cgatattgag gctgtttaga ttttgtcatc tctttccttt cctagtgccc
     9601 ttttaagggt tggatttgat ctctaatgaa ttgaactaac tcccgttcaa attggctctt
     9661 gtatttgagt ttattcatgg cagaatcacc ttgtttttct ttataggctt ggtagtctag
     9721 ggattctttt aaggttgaca tgcccacttg tttggtagag ttagcactat gataattagt
     9781 cgccacaaag gctaatttgt caggatctgc cttccattgg tccgcaaagt gtttgatggc
     9841 cctttggatc ttatcaccaa tgaggttatc taactcataa gcaatgcttt tcccttcata
     9901 ggctttgggt tctttttgga tatcttgcca taactcagct agtgagtcag ccatagcaga
     9961 gtttgatttt gccaaatctt ggatgtattg atccatggga ttgtcattga gcctttcctg
    10021 aagagcttct tgttcttgat cgacaaaggc ttgaattaag gtcaagatat agtgatagtt
    10081 gatatcatcc atctgaacgc tttctagctc atagtcgata ttgatctctg ggatggcttc
    10141 gtcatcttct cttcgttttc gtatttctgc aatgacattt tggtaagtgc ctttataagt
    10201 atcaatcact tcatctgata acccaacctc actcaacagt gtttcattaa agtcactata
    10261 gacctgtaca gatgcaaaga gtttatcaaa cgcttgaaag gctttggcgt attgtttgag
    10321 aaaagctgtc tgtgcgctct caatagttgg gaaagcgtct ggatcaggaa ctatattttt
    10381 taatactgtt acgttttcaa ggaatcttgc tttttcttct tcccaagaag gggccaaaac
    10441 gtcgttttca cccccattag agtagaggct aagcgctttg tcgacagctt ctttaaaacg
    10501 aagtggtgtt tggaaagtca caacctgacc gtaatgtttt ctactttcaa agatacggtt
    10561 ggttcgtgag aaagcttgaa taatgtgttg aggtttcata ggctggcgat cgatgaagat
    10621 ggttgataaa caaggcgcat caaagcctgt taagagacgg tcaaccacaa tcacgaggtc
    10681 taattgttca tgacgatctt tgaatttatc tcttttacgg gctaagcgat catttaaatc
    10741 tctgttatag ccttgtaagt tatcgatggt aaagttagtg ccaaagaggc tattatagtc
    10801 ttctagattt tcagccattt tatattgtct actgatagac gcattgtcat tttcagtgac
    10861 agaataagta atagctacct ttggaaagtc tggtagtttt tctttgacct tcttagaaat
    10921 gactaaatcc gtttcaccag ccttaacttt cttcatcaga tcataatagg cttgggcacg
    10981 agcaatactc ttaacggtta gtaaaccttc gaatgtctga ccaattccat tattaaaacc
    11041 aagtttcttg cgtgattgat taatgatact atctaagaca gctaacatat gttcttcatg
    11101 atcataagct tcttccggaa tactgtcttc aggcatatca ggaatggttg tcttatactc
    11161 aacttgaaag cctagaaccg ctttatcatg aatggcttct ttaacggtgt attgatggag
    11221 acatttgccg tattgctgtt ccgttgtttg ggctaaatca cctaattgag cacgcttatt
    11281 ttccacaaag ataggagtgc cggtaaagcc ataccagaga ctgttacgaa aagtattcgt
    11341 gagataacgt tgacgttccg gtgtgacagc acggtggcat tcgtccacaa caaagacaac
    11401 atttaagtgt gcaagacggt ctttaagttt cttgaatttt ggagtgtcat aactttccat
    11461 ctgactgatc atggcattga gtttttgaat ggtggtgacc acaacacgac gatcactgga
    11521 ttctaaattt ttgatgagtt gtctcgtatc ttctgtctca tcgacatcaa agatatcatt
    11581 ttgcgcatag gattgaaaag cagaagcggt ctgattatct aaatcctttc ggtcaatgac
    11641 aaagatggat ttttcaacgg ccggtatttg aaggatattg cgagccactt tataggaagt
    11701 taaggttttt ccagaacctg ttgtgtgcca gatatagcca gacttgcggt gacgactcgc
    11761 ttcagcgacg gcttcgattg catgaatctg ataaggacga aggagaatta gtgctttttt
    11821 atcatcatca atgaccgaat aagttatgac catttggtga gcacgaggga tagacaaggt
    11881 ttctttggca aaggcaaaga gatctttttg tggcttgttg ttttgatcta cccattgggt
    11941 caagaagtta gggtttaatt tattttcttt agctgcagcg atataccttg tatctgtttt
    12001 atttgagacc acaaacattt gtaaggttga aaagatacct ctaaactggc cttctttatc
    12061 atactttttg acttggttaa aagcttcaat gcattgatga ttctgagatt ttaattcaat
    12121 ttggatcata ggtaagccat tgatgagaag tgtcacatca cctcgtctat cacgagaacc
    12181 agagaaagca acttgattgg caatctcata aacagaagtt ccaccagcca cattgtctgc
    12241 tttaacgact tctaaacgaa tcgttcctag ttttgcatct tcgcgttgca cttgtacttt
    12301 agcaatgccg ttttcaccag ctaaccattt agccgcttca tagtaattga caaagttaag
    12361 ttgattctta atctgctctt tttcactagc tgttaaaggc tcctcgttca gatattgcgt
    12421 gttattttgc gctaagatct taaagaaatt atcccataaa gcatcttcag tttttaattc
    12481 tttacgatat gtccattgac tttcacctgt ttctaagaga tggatcaact ctttttcaag
    12541 ttcaagttcc gttttagttt gatttcccat ttttaatccc cattcgacat gatatagtaa
    12601 tattatatca ttggcggatc ctttttagaa tggcaaagct attgaaacct tccaaacagt
    12661 ctttttttga ttagttgaat gcttaagatc ctagcaacta aacaaagcta tgactatgta
    12721 aatgcaatcg agaaagttct tgtatttttg agtttgcttg acaataattt aaggtgaaga
    12781 aagtaataag acaacattag taaaaaggtc gagttctcaa aatagataaa aaacttaaga
    12841 cagatctagc ttgactatta atagggcttt aaaggacgat aatctgctac aatatacaga
    12901 aaaggaattt attgaagata tgaaaatttt ggtagccata gattctttta agggatcggt
    12961 aacgtctcca gaacttaaca ctagtgtagc tcaagccctt ctttctgtcg ataagcagtt
    13021 agttattgaa acaagagcta tcgctgatgg aggagaagga agtttagcag ccctctcaca
    13081 aaccgtggcg gggaggtggc atcaagtaaa aaccattgat ctattaagac gcccgattaa
    13141 agtcgcttat tatcgtcacg caaagcaagc ttttattgaa tctgcgagta ttattggtat
    13201 tgataagatc acccccaatt cagtaaccta tgcacaagcc acttcctatg gtttgggttt
    13261 ggcagttaaa gatgccattc aaaaaggagc tactcaaatc gaaatcatgc taggaggaac
    13321 aggcacttct gatggtggca aagggttttt ggaaagttta aactatgatt tcatgacagg
    13381 aagatcttat cttgatactt tagcatcacc tgttacgcta ttagggctga ctgatgtgac
    13441 caatccatat catggccctc aaggatttgc tgcggtcttt ggccctcaaa aaggtgggag
    13501 tcttagtcaa attgaagaaa ctgatcaaat tgcaagtaac tttgctaaaa aagttttttg
    13561 ccaaacaacc attgatttac agacaatacc aggaagtgga gcagctggag gattaggagg
    13621 tgccattgtc ctattaggag gcaccttaac tagtggtttt agcaggattg cagagctact
    13681 aaatctggat aattcccttc agtcttgtga tttagttatt actggagaag gatgcctgga
    13741 tacacaatca caatctggca aggtacctgt tgcgattgca agaatggcta aaaaatatca
    13801 agttccaacg attgctctat gtggttctgt aaagattgag acaggactag cagcagaaga
    13861 ctttttggct gttttttcaa tacaacagca gccaatttcc ttagaagcag cgatagataa
    13921 aacaacaaca ctttctaata tcaaaatatt agcagctaac cttatgctat tgatagctca
    13981 gtttaataag taaactcatc tattttcgat tgtgtagcat tcatttggcg gttaaaagta
    14041 acctatgaag aaggagacgc acgagctaac tcattagcat agtatgaaaa acagaaacat
    14101 tttg
//
LOCUS       DAUNLR010000044        13959 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUNLR010000044 DAUNLR010000000
VERSION     DAUNLR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13959
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.044"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            1..1043
                     /locus_tag="VLL59_001345"
                     /pseudo
     CDS             1..1043
                     /locus_tag="VLL59_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366757.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(1143..1215)
                     /locus_tag="VLL59_001346"
     tRNA            complement(1143..1215)
                     /locus_tag="VLL59_001346"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1180..1182),aa:Lys,seq:ctt)
     gene            complement(1216..1412)
                     /gene="ssrS"
                     /locus_tag="VLL59_001347"
     ncRNA           complement(1216..1412)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VLL59_001347"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(1501..2769)
                     /locus_tag="VLL59_001348"
     CDS             complement(1501..2769)
                     /locus_tag="VLL59_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HER6509467.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELDPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDSSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKAIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            complement(2802..3368)
                     /locus_tag="VLL59_001349"
     CDS             complement(2802..3368)
                     /locus_tag="VLL59_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HER6509468.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRYLPQEITVMRYHSIVVDQLPKGFSVAARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            complement(3401..5158)
                     /gene="pabB"
                     /locus_tag="VLL59_001350"
     CDS             complement(3401..5158)
                     /gene="pabB"
                     /locus_tag="VLL59_001350"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HER6509469.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIENVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLDNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHHEMRQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNTWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVRVDKLCEVEQYSTVWQMTSTIVGDLKADCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVQHKTAFLYRHKQIFDLKTTAKVEHKKIAFL
                     EQHLNRLKEAATYFAYPYDEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFIQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLNALLAKSQA"
     gene            5359..5829
                     /locus_tag="VLL59_001351"
     CDS             5359..5829
                     /locus_tag="VLL59_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HER6509470.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFEAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKVDFGLEWNAQAFEEGQQGLEEGESYPYPRY"
     gene            5831..6175
                     /locus_tag="VLL59_001352"
     CDS             5831..6175
                     /locus_tag="VLL59_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HER6509471.1"
                     /translation="MIHEMMLSPKPFEMIASGTKTIELRLNDEKRQKVQVDDTIVFVR
                     TDDSRQMLWTKVVGLYYFDDFAQLYQSLPLDNCGYRKEELEMARPEDMERYYSQEQQA
                     QYGVVGIELSVL"
     gene            6187..6627
                     /locus_tag="VLL59_001353"
     CDS             6187..6627
                     /locus_tag="VLL59_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HER6509472.1"
                     /translation="MTSSTQACVFSGVKIALMQEQHLVTILRDNKSTIPFPDTWDLPG
                     GGREGLETPFECVQREVMEELGIAISQDMVVWEKAYQGVMNPKTYSIFMVAMISKDLV
                     KAIHFGEEGQAYKLVPMKDFLADKKAVPQLQERLAAYLAEKSDQ"
     gene            6722..7675
                     /locus_tag="VLL59_001354"
     CDS             6722..7675
                     /locus_tag="VLL59_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HER6509473.1"
                     /translation="METWQEVTVHVHRDAQEAVSNLLIETGSQGVAIADSADYIGQED
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVTVTINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            7675..8424
                     /locus_tag="VLL59_001355"
     CDS             7675..8424
                     /locus_tag="VLL59_001355"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HER6509474.1"
                     /translation="MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLADKAEVVLVFDDG
                     VKYLAKVTNSMAHELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAASAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            8782..10968
                     /locus_tag="VLL59_001356"
     CDS             8782..10968
                     /locus_tag="VLL59_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HER6509475.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSTMLADPEAKITSLLGTQMVVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDLINFVWVSVLFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQTRPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPEVNMSQLT
                     SKPTPAKDFKHVTEKVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTSGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL"
     gene            11051..11869
                     /locus_tag="VLL59_001357"
     CDS             11051..11869
                     /locus_tag="VLL59_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HER6509476.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYHEG
                     VAILSKQPIHVSDILVSAMNDETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLVGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIVRSSKITFEGGDAPVVSDHYGLEVTLDWR"
     gene            complement(12263..12745)
                     /gene="nrdI"
                     /locus_tag="VLL59_001358"
     CDS             complement(12263..12745)
                     /gene="nrdI"
                     /locus_tag="VLL59_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HER6509477.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            13123..>13959
                     /locus_tag="VLL59_001359"
     CDS             13123..>13959
                     /locus_tag="VLL59_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509478.1"
                     /translation="MLTTKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAETAGASM
                     TPQERTRKIEEIKKSLESYPKMNDSKFWESTWYGGSRFKDNDFQDALKKFTEQRLKDI
                     LELIEKGATKGDKGDAGPKGERGPAGPEGKPGKDGAKGDTGPRGERGEQGIQGEQGKA
                     GEKGEKGDKGDTGERGEKGETGATGAQGPQGEAGKDGAPGEKGEKGDRGETGAQGPVG
                     PQGEKGETGAQGPAGPQGEAGKPGEQGPQGEAGQPGEKAPEKSPEGEAGQPGEKAPEK
                     SPE"
BASE COUNT         4145 a         2630 c         3315 g         3869 t
ORIGIN      
        1 aaaaatagtt cggtcttaaa aaaaaagcgt gaggctatga atgaagctat gagaatggag
       61 caacaaaagt cactagtgaa ttatcttctg atataacttt gtatgaacta tggtttgagt
      121 ggtataactt agtcattaag cctagtgatt tagcagagac tactaagaat aaatatttta
      181 taagaggttc gatgattcgt aagcattttg ggaatcagaa agtaaataaa ataaaacata
      241 gtgcgtatca aagaaaattg aatacgtatg ctgaaaaata cactaaaaat catgtcagga
      301 gattaaattc tgatataaaa aaagtcattc agtttgcaaa aagagatggc attttattat
      361 ctgactttac agatggagtt gtcagagctg gtaggcaatt tgttaaggat gcagatgata
      421 aatatctaca tagtatttct aattataaga aagtaatatc ttatttagaa aataatttag
      481 attactcaaa tagtatcgtt tattatttat tactggtgtt atttaaaaca ggtttatgag
      541 taggtgaggc tttagcattg acttgggatg atgttaattt tgagaatcta gaaatcaaga
      601 cgtatagaag atttagtggc actaagggaa cttttagtcc ccctaaaaca aaaacttcta
      661 tccgcactat tcctattagt caaactttag cattaatctt aagaggtttg aaggatgatc
      721 agcaagttat attgaaaaat ttaaaaattg tcaatataaa taatcaaata ttttatgact
      781 ataggtatgg agtttcatca aatagtgcca ttaataaaag tttgaaaaat gtactaaata
      841 ttttaaatat tgattccaaa atgactgcaa caggtgcgag acatacctat ggaagttatt
      901 tattggctaa gggtgttgat atttgggtag ttgcaagaat aatgggttat aaggatatta
      961 cacagttact tgaaacttat ggccacgtct tgacagaagt aatcaataag gaatatgaaa
     1021 cggtcagaag tttagtatct taaagctaat ttttaaagaa tatcttctag aacaaattta
     1081 gaacaaattt gccaaaacaa agaaaaaagc ctttaaacaa aggtttttta tgtatagttg
     1141 tataccccct acagggctcg aacctgtgac ccatagatta agagtctact gctctaccaa
     1201 ctgagctaag gaggcaagaa tgctgtattg gcaccggtga tccacgtttt tgtattgagc
     1261 ccgcgcagta taagcaggtg ggtaacgcgc tctttcttgg aagttgcgtc cgcgtgaaac
     1321 ggcttgcaga ctagaaagag tctttgtttc ccgaaaatac aaagaaatag tcggtcaaca
     1381 cttagatgtg gattcgtatg ccacagcaat gtttctgtac ttttataata ccacttttta
     1441 aaattttttc aagcaaaatt atcgattttt gaaatcggtt gcgattttta aaactagcag
     1501 tcagtctgag agcttatcaa tacgctcttt atttgaacca agtgcgcgtt cgtatttacc
     1561 ggtttcattg gcttcaaaat aatgatgtcc tactaattta tctggtaggt attgttgttt
     1621 gacccatttt tcagggtagg cgtgtgggta gaggtaatct ttggcattgc ctaggtcctt
     1681 gctgccagca taatgcccgt ctctaagatg ccttggaatg gggaggttac ctgatgttct
     1741 caaatcagct aaagctgcat ccatagctaa ataagctgaa tttgatttag gagatagagc
     1801 caaatcaatg accacgttag cgataagaat acgagcttct ggaaaaccaa tgcgttgggc
     1861 ggcatctagt gcggtgacgg tatgaacttg ggcgtcaggg ttggctaagc caatatcttc
     1921 gtaagcaata atggtcaatc gtcttgctaa actaggcaag tctccagctt ctactaaacg
     1981 agcggcgtag tgcaggctgg cattgacatc ggagccgcga atagcttttt ggagggctga
     2041 tagcacatca taatgcccgt ccccgttttt atccatggta atataactac gctgcagact
     2101 attttccatt gtctctagac taatatgacg gctactatct tcattaggag aagtagacat
     2161 gactgctaga tccaaggaat tataagcaga tcgtaggtct ccatttgtgg cggtaacaat
     2221 gaaatctagc gcctcatcat caattgtcac taaaaaagga aatccccgtt ctttgtcgga
     2281 aattgctagc tgaatggctg ttttaatatc ctcgttagaa agtggatcca attcaaaaat
     2341 ctggaccctg cttctgatag cgggtgtcac tgaaaagaag gggttctcag tggttgcgcc
     2401 aatcatgata atggtgccat tctcaagtaa aggtaaaaga aaatcttgtt ttgtcttgtc
     2461 aaggcgatga atctcgtcta gtaataatac caagccacca gaaaatttag cttcttccgc
     2521 aatttcttgg agacgttttt tgctgtcaat ggtggcatta aaggtccgaa aggcatatct
     2581 agtagtacca gcaatagcag aagcaatgga agttttaccg attcctggag ggccatagag
     2641 gatcatggac gatagtctat ttgcttccac catgcgacgg atgattttgc cttcgccaac
     2701 aaggtgtttt tgtccgatga cctctgaaat ggttttgggg cgcattctga gcgctaaatg
     2761 atcaggcatg taactgtcct cctttctttt gggggatggg attaacgggg aatagctgcg
     2821 atgaagttag caatcatagt catgccatca ggagttccga tgctttctgg gtgaaattgt
     2881 agcccaaaaa gtggcagggt gtggtgttca aaggccatga tttcttgatc gtcacagtct
     2941 ctagcagcta cgctaaaacc ttttggtaac tgatccacaa cgatagaatg gtaacgcatg
     3001 acggtgatct cttgtggcag gtagcgaaaa agactagcag ggccttgcgt ttcaatggtg
     3061 ctttgtctcc catgcatgac gcgtttggcc aagcgtaagg ttccccctaa tgtttcagcg
     3121 atcgcttggt gtcccagaca cactcctaag ataggttttg tttggtaaaa gtcttgaatg
     3181 agttttggca tttggttggc ttccttgggc caaccaggac caggtgagag gactagagcg
     3241 ttagcctttt tggccatgtc atataagttt gggtcttggt tatacaagac aatcgtctcg
     3301 tcaaattcac ttaaatattg ggcgaggttg taggtaaatg aatcgtaatt atcaattaag
     3361 agtatcatag gttccttaat aacaaaagat gagtggcagt ttaggcttga ctcttagcta
     3421 agagggcatt aaggtgagta agctcaaggt tgagaggata gaggccacgg acagcatttc
     3481 ctccaaaaat agcgctagcc tcttttaaat cagctagtgt cacctctttt tcctgagctt
     3541 gaccagtagc tagcagctct tggcgaaaaa gtcctggtaa aatccccaca gccactggtg
     3601 gtgtgtagag ggtctgaccc agctggataa aaagattgcc gatagacgtt tccaataatt
     3661 gccccgcttg attatagaat agctgttcat aagatttttg ctcaatatga ggccggtagc
     3721 tggtcttaaa gtaggtaaaa ggcgaagctg tcacgtcctt cttctgtaaa gagagttgag
     3781 ctgtcagaaa atcggctgac aaaggttcca agggttgatc agagaggcta atctttccat
     3841 ccttggataa acgaatcatc aagcggtagg cagcattatc cttattttcc aaataggttg
     3901 acagttgttt ctgcaaagct ttctcatcgt aagggtaagc aaaataagtg gctgcttctt
     3961 taaggcgatt gaggtgttgc tcaaggaagg ctattttttt gtgttccacc ttggcggttg
     4021 ttttgaggtc aaagatttgt ttgtgccgat agagaaaagc tgttttatgc tggacttcct
     4081 cgtattcgtc ttcccacttg ctttgccaag tgataccgcc tccgacacca taggtagctt
     4141 gattatgact gagctggatg gttctaatgg gaacattgaa gaaacggcga ccatcaggta
     4201 ggcaaatgcc aatacttcca caataaatcc cccttggttt tggctccaga gatgtgataa
     4261 ttgccatggt ggagacttta ggagcccccg tgatagagcc acaaggaaag agagctgtga
     4321 gaatgtctat caggtcacag tccgctttga ggtcaccaac aatagttgag gtcatttgcc
     4381 agacggtaga gtattgttcc acctcacaga gcttatcaac acgaacactg cctgtttggc
     4441 aaatttttcc catgtcattg cggagcaaat ccacaatcat catgttttca gagcgatttt
     4501 tcccgtcagc ttggagccag tcatgttctt gttgatccag ccaggtgtta accccgcgct
     4561 tagtggtgcc tttcataggc ctagtagtta acctgttgcc ctcttgttta aagaacaact
     4621 caggactagc cgaaataaca gcaaagtcat catgggcgat ataggcattg tagccagcag
     4681 cctgttcaac gacgagttta ttgtaaatgg ctaagctgtc agctgcattg agttcctgag
     4741 ttaattgaag ggtgtagtta acctgataag tattgccctg tcgcatctca tggtgaatgg
     4801 tttcaatggc tttttgataa gcttcttttt gagtggcgct gacccattgg ttagggatag
     4861 taatgctgtc ataatcaaga ggtaggtctt ttttttgaca ggttttgtgc actgtaaaat
     4921 aggcaaggta ctcgttgtct agtctgtcat tatgggtttg tagggcattg tcaaaaaaag
     4981 cagctgcttc ataactgaga tagcccacca cgtaatagcc cagctgttgg tagtgttgta
     5041 cgttttcaat gactggaccg acctgatcta aggacttggc taccaattct actagtggct
     5101 catcaaaaag atagcgttgc ccgagctctt tgaaatcaat aatcgttttt ctatgcatac
     5161 ccaaattata tcataaaagc ggttgctaga ggtgatcctg ccattaagat cttctcttat
     5221 ggtcaatatt agtcaaatat gttataattc agttaataaa agttataaca gtacgctcag
     5281 catgtcaaag taagtaaact aatgaggtct tacaaagcct tatacagcaa cagttagaaa
     5341 gattaggtat aaaaaaagat ggcaaaatat ggctttttat cagtattaga agaagaaatg
     5401 gataagcatt ttcagtatga ttatgctatg gattgggaca agaaaaatca tgcggttgaa
     5461 gtgacttttg ttttagaagc tcaaaataaa gaggccataa aaaccattga cgatagtggc
     5521 gaagtgactc aagacgacat tgtctttgag gactatgtgc tcttttacaa ccctgccaag
     5581 tctcaatttg aggcagcaga ttatttggtt accattcctt ttgacgccaa aaagggcttt
     5641 tctcgtgaat tcttagctta ctttgcgcaa tttctcaatg atgtggctat tgaagggcac
     5701 agcgatttga tggatttctt agcagatgac agcaaggttg atttcggctt ggaatggaac
     5761 gcgcaagctt ttgaagaagg tcaacaagga ttagaagagg gagaaagtta cccctatcca
     5821 aggtactaag atgatacatg agatgatgct aagccctaaa ccttttgaga tgattgcctc
     5881 aggtacaaag acgattgaat tgcgtctgaa tgacgagaag cggcaaaagg ttcaagttga
     5941 tgataccatc gtatttgtta gaacagatga tagtcgtcag atgttgtgga caaaggtggt
     6001 tgggctttat tattttgacg acttcgctca gctttaccag tcgttaccct tagataactg
     6061 tggctatcgg aaagaagaac tggagatggc tcgtccagaa gacatggaac gctattatag
     6121 tcaggaacag caagcccagt atggggtagt cggcattgag ttatcagtgc tgtagaggag
     6181 acgattatga catcatcgac acaggcatgt gttttttctg gagtgaaaat tgctttaatg
     6241 caagaacaac accttgtgac cattttaaga gataataagt ctaccattcc ttttcctgac
     6301 acctgggatt tgcctggcgg gggacgagaa ggtttagaaa caccctttga atgtgtgcaa
     6361 cgtgaagtga tggaagaact aggaatagcg atttcgcaag atatggtcgt ctgggaaaaa
     6421 gcttatcaag gggttatgaa tccgaagact tactctattt tcatggtggc catgatcagt
     6481 aaggatcttg ttaaagccat tcattttgga gaagaaggtc aggcttacaa gttggtaccg
     6541 atgaaggatt ttttagcgga taagaaggct gtgcctcaat tacaagaacg attggcagct
     6601 tatctagctg agaaaagtga ccagtgagat gagtgttggt atttcagtgt ttaaggattg
     6661 ttagaaatga cacaagtgtc agaggctcag agaaattgtt aaaaggagaa aggacataac
     6721 tatggaaaca tggcaagaag tgacggttca tgtgcatcgt gatgcgcaag aggctgtttc
     6781 aaatttgttg attgagacag gcagccaagg ggttgctatc gcggatagcg cagactatat
     6841 tgggcaggag gaccgttttg gggagttata cccagatgtg gagcagtctg acatgatagc
     6901 tatcacagcc tattacccaa gtagcactaa tttggcggat gtgaccgtga ccattaatga
     6961 acagttagcg gagttagcta gttttgggtt acaggttggt caggttactg tggacagtca
     7021 ggaattagct gaggaagact gggcagataa ttggaaaaaa tactatgaac cagctcgcat
     7081 cacgcatgat ttaaccattg tccctagttg gacagattat gacgcttctg ctggggaaaa
     7141 ggttattaag ttagatcctg gaatggcatt tgggacaggg acacatccca caactaagat
     7201 gagccttttt gctctagaac aaatccttcg tggtggtgag acagttatcg atgtagggac
     7261 cggatcaggt gtcctctcga ttgccagttc cttactaggt gctaaaacca tctacgctta
     7321 tgacttagat gatgtggctg ttcgagtggc tcaagaaaac attgatttga atcaaggaac
     7381 agacaacatt catgtggctg ctggcgacct tttaaaaggg gttagccaag aagcggatgt
     7441 gatcgtagcc aatatcttgg cggatatctt agtcttattg actgatgatg cttaccgttt
     7501 ggtcaaaaag gaaggttacc ttatcttatc tggcatcatt tctgagaaat tggatatggt
     7561 tctggaagct gcctttagcg caggcttttt cttagaaact cacatggttc aaggcgagtg
     7621 gaatgccctt gtctttaaaa aaacagatga tatctcagga gtgattggcg gctaatgcaa
     7681 cagtatttta ttaaaggcaa agcagaaaaa aaggtaacaa ttaccgataa agataccatc
     7741 aagcacatgt ttcaagtgat gcgcttggct gacaaggctg aagttgtctt ggtctttgat
     7801 gatggggtga agtatttagc caaggtgacc aatagtatgg ctcatgagtt agagattata
     7861 gaggctttgc cagatcaggt ggaattgcct gttaaggtga ctattgcttc tggatttcct
     7921 aaaggagata agttagacac gattgcccag aaagtgactg aattgggagc cagtgcgctg
     7981 tggggctacc ccgcagactg gtcagtggtc aaatgggatg gcaaaaaatt agctaaaaaa
     8041 gaagacaaat tggctaagat tgtattagga gcggctgagc agagcaaacg aaatagggtg
     8101 cctgaagttc acctttttga acataaagca gagtttctaa aaagcctttc tagctttgat
     8161 catatcttca ttgcttatga ggaaacagct aaggcaggtc agctagcgac cttggcgcgt
     8221 gaagtaaaag aagttaagcc aggggcaaaa atcctcttta tctttggacc agaaggggga
     8281 atttccccaa ctgaaatcac tcagtttgag gcagcaagtg ccattaaggt gggcttaggc
     8341 cctcgcatta tgcgagcaga gacagcgccg ctatatgcct taagtgctct tagttatgct
     8401 ttggaattgc aggcatcaaa ataagtaagc tgttgcttac tttagaaaga agaggctaaa
     8461 gaaacgaaca ggcagttcac gattgtgtca acggcctttt tttattgctt cttgtttttt
     8521 tgaagagcgt tgatgggctc atcaccaaaa aaggaaatgg gctcttgtca tctttttggt
     8581 gagttacact actatattaa tgaagaaaaa cgactaacat ctgtctaaga aaacgcttta
     8641 caaattgttg cgaggctagt ataataaagg tatcagatca atgaaagcga ttgcatcact
     8701 gagttgcagt ctatatcatt gtgtcacaaa agcgccttaa gggcagctat ggctaaaagg
     8761 ggataataaa ggagagatag aatgaaaaca tcattcaagc aactgtttcg tttcgaattt
     8821 tggcaaaaat ttgggaaatg tcttatggtc gttattgctg tcatgccagc ggctggttta
     8881 atgatcagta tcggaaactc tattccaatg attaaccacg actcagcatt tttggcatct
     8941 ctaggcaaca ttatcgctca aattggttgg gctgttattg ttaaccttca cttgctattt
     9001 gccttggcca ttggtggtag ttgggctaaa gaaagagctg gaggggcctt tgcctcaggt
     9061 cttgcttttg tcttgatcaa tcggataaca ggcgcttttt atggcgtgtc tagtactatg
     9121 ctagctgatc cagaagcaaa aatcacaagc ctccttggca ctcaaatggt cgttaaagat
     9181 tatttcacca gtgtcttgga atctccagct ttaaacacag gggtttttgt tgggattatt
     9241 gcagggttcg taggagcaac ggcctataac aaatactata attaccgtaa acttcctgaa
     9301 gttttgacct tctttaatgg gaagcgtttt gtaccatttg tcgttatttt acgttctatt
     9361 tttgtagccc ttattttggt tgttgtttgg ccggtgatcc agtctgggat taacagtttt
     9421 gggatgtgga ttgcctcttc acaagattca gctccaatcc tagccccatt cctatatggt
     9481 accttggaac gtctcttgtt gccatttggt cttcaccaca tgttgacgat cccaatgaac
     9541 tatacagctc ttggtggaac ttatgaggtc atgacaggtg cagcagcggg gacaaaagta
     9601 tttggtcaag accctttgtg gcttgcttgg gtaactgacc ttgttcacct taaaggatca
     9661 gacgcttcag cctatagtca cttaatggat agtgtgactc cagctcgttt caaagtagga
     9721 caaatgattg gagctaccgg aacattgatg ggggttgcct tagccatgta ccgtaatgtg
     9781 gatgccgata aaaaacacac atacaaaatg atgttcatct cagcagcggc agcggtcttt
     9841 ttgacagggg taactgagcc acttgagtac ctatttatgt ttgcagcaat gccactttac
     9901 atcgtctatg cccttgttca aggagcttca tttgccatgg cagaccttgt gaatctccgt
     9961 gttcactcat ttggaaatat agagctacta acccgcaccc ctatggctct taaagcaggc
    10021 ctaggcatgg atttgattaa ctttgtttgg gtttctgtcc tctttgcagt tatcatgtac
    10081 tttattgcag atatgatgat caagaaaatg catctcgcaa cagctggccg tttaggcaac
    10141 tacgatgccg atatactggg tgaccgtaac actcaaacaa gacctaccca agtagcagat
    10201 agcaactctc aagtcgtaca aatcattaat ctccttggtg gggcaggcaa tattgatgat
    10261 gttgatgctt gtatgacgcg cttacgagtg acggtcaaag accccgctaa gattggcgct
    10321 gaggacgatt ggaaaaaagc tggcgctatg ggcttgatcc aaaaaggcaa cggcgttcaa
    10381 gcggtctatg ggcctaaagc agatattttg aaatcagata ttcaagattt gctggactca
    10441 ggggctgtta ttccagaagt caatatgtca cagctcacta gcaaaccgac tcccgcaaaa
    10501 gattttaaac acgtgacaga aaaagtgcta tcagtggcag acgggatggt tctcccaatc
    10561 acaggtgtga aagaccaggt gtttgcggct aagatgatgg gagatgggtt tgcggttgaa
    10621 ccaacaagtg gtaatatcta tgcacccgta gctggccttg tgaccagtgt ctttccgacc
    10681 aagcatgcct ttggtttact gacagataac ggtcttgaag tgctggtgca cgtgggactt
    10741 gataccgtcg ccttaaatgg tgtgcctttt tcagtcaaag tctcagaagg acaacgggtt
    10801 catgcaggtg acctattagt cgtagcagat cttgctgcta ttaaatcagc agagcgtgaa
    10861 acaaccattg ttgttgcttt taccaacaca acagagatcc aagatgtgac cttgacatct
    10921 ttaggagctc agcctgctaa gactaaagta gccaccgtag aactttaaca aaacatcaca
    10981 agacagtgat aggtaatagc catagctggt ttaggcccta tggctcttct tgtcttataa
    11041 aggaggatta atgaccaagg tattaacact gaatacccat tcgtggatgc aagccaacac
    11101 tcttaaaaaa ttagttgctt tggctgagca tattttagct gaaaaatacg atatcatttg
    11161 cttgcaagaa atcaatcagt taatcgagag cgagctggct acagatttac caagatatca
    11221 agctctttca gggacaccaa gcattcataa agaccatttt gcccttctct tgatccatta
    11281 tttacaaaaa cgagggcagc actattattg gtcttgggct tataaccata ttggctatga
    11341 catttaccat gaaggcgtgg caatcttatc aaaacaacct attcatgttt cagatattct
    11401 cgtgtcagcg atgaatgatg aaacagacta ccacaccaga cgctcactca tagccaaaac
    11461 cacgttagat ggcaaagaag tcgctgttgt caatgtgcac ctatcttggt ttgacaaggg
    11521 gtttttaggg gagtgggaga aattagaaaa agagctgctc acactaaact gtcccttgct
    11581 acttgtggga gattttaaca atccaacgga tcaagacggt tatcaagtga tgatgggtag
    11641 ccccctagac ctacaagata gccataaggt tgctgaccat gtgtttggtg atcatagcat
    11701 cgtggctgat attgatggct ggcaaggtaa caaagaagcc ctcaaggtgg atcatgtctt
    11761 taccagtaag gacttcatcg tccggtcttc taagattacc tttgaaggcg gagatgcgcc
    11821 agtcgtcagt gaccactacg gtctagaagt gacattagac tggcgttaga gcatgtgcta
    11881 acaggcacac catataggag aagccaagac atataagaaa ctgcgatcgt ctagggggat
    11941 taggagaaca caaagaggtc taaccagctc aaggtagagc tggttagacc tctttagtca
    12001 tgtcagtaac cctagaaaac cagggctttt tttgtcacca accatctgag cttcacagaa
    12061 agtaccacca agcgtacagt tgtcttgcta aagtctgcat gggggtattt ctaggagtgc
    12121 ttggtgtgat cccaagcccc aagaagcact gtgatcgctc ttttaaaagg ctgagaaatc
    12181 acaaggcgta gggtagggcc ctctgtagtt attgtcctaa aagcgctctt ttttaaaaca
    12241 gctatgatca tctatagact gtctagctgt tgggtagtgt ctgtgtgtca ttagacgagt
    12301 gtctggagct ggcctccatg atgacctggg ctaaccgcga aatgtcatca ggagtccctc
    12361 gcagctcaaa atcacctagc agtgggaaac caaagcgttt ggcatactgt ttggctgtca
    12421 ggcaatactg atggttaaag tttttgttgc ctgagccaat aatcccaaga caacgctggg
    12481 cgttgccatg ggcagcaata aactctccca aaggagtggt gaggatctcc acctcaccag
    12541 agtcaacgcc atttccgcct tctagataag tgggtagaat cgccacaaac tcttctttga
    12601 cgggaaaagt ctcgtgcttc aaatctttaa tgttaatctg tttgacatgg taatcgtaat
    12661 tgtctgctag ataaagggat agccgcttga caaagctaag ggtgttgcca ctgaggctaa
    12721 taaaaacaag ggtaatctga ggcataagtg tctccttttt ttatcctaca aggtttcttc
    12781 ataagcttac cacaatcaag accaacaaac aagtaaagaa gaaacctagc ggtatccaac
    12841 cagacaagaa ggtacaagca gtcaaaaaaa gcaacatttc aaaaaagagt gaccttaaag
    12901 aaaggatgcg gatgctctcg acttaaaaac gaggcaggca agtgccaaag tgggcctctg
    12961 atctccacaa aagagcgatc agtcaaaatc taaaagatga acaacaaaag agaactttac
    13021 aatcgttttc acactctatt ataatactat tataaataat caggtctagc taccatgtta
    13081 ttttatctaa aacatatcat ctagagaaag agagaacaac atatgttgac aacaaaacac
    13141 cataatctca acaaactagt ctggcgctac gggctaacct cagccgcagc cgtccttcta
    13201 gcctttggag gcggggcaag cagcgttaag gctgaaactg caggtgcttc tatgacaccg
    13261 caggagagaa ccagaaagat agaagaaatc aaaaaaagtc ttgaaagtta tccaaaaatg
    13321 aatgacagca aattttggga aagcacttgg tatggtggta gtcgatttaa agacaatgac
    13381 tttcaagatg cactaaaaaa atttaccgaa caaagactta aagatatttt agagctgatt
    13441 gaaaaaggtg caacaaaagg tgacaaaggc gatgctggtc ctaaaggcga gcggggccca
    13501 gcaggcccag aagggaagcc aggcaaagat ggagccaaag gtgacaccgg gccgagaggt
    13561 gagcgcggtg aacaaggaat ccaaggcgag caaggtaaag ctggcgagaa gggtgaaaaa
    13621 ggcgacaaag gtgataccgg tgagcgcggt gaaaaaggtg aaaccggagc aactggcgca
    13681 caaggcccac aaggtgaagc tggtaaagat ggagctccag gcgaaaaggg tgaaaaaggt
    13741 gaccgcggtg aaaccggagc tcaaggtcca gtaggcccac aaggtgaaaa aggtgaaact
    13801 ggcgcacaag gcccagcagg cccacaaggt gaggcaggca aaccaggtga gcaaggccca
    13861 caaggtgaag caggtcaacc aggtgaaaaa gctccagaaa agagcccaga aggcgaagca
    13921 ggccaaccag gcgaaaaagc tccagaaaag agcccagaa
//
LOCUS       DAUNLR010000045        13698 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUNLR010000045 DAUNLR010000000
VERSION     DAUNLR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13698
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.045"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            442..918
                     /locus_tag="VLL59_001360"
     CDS             442..918
                     /locus_tag="VLL59_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HER6509479.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            976..2157
                     /locus_tag="VLL59_001361"
     CDS             976..2157
                     /locus_tag="VLL59_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HER6509480.1"
                     /translation="MPLIPDKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            2147..3394
                     /locus_tag="VLL59_001362"
     CDS             2147..3394
                     /locus_tag="VLL59_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HER6509481.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVSISPEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLLYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEIAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(3453..5105)
                     /gene="fbp54"
                     /locus_tag="VLL59_001363"
     CDS             complement(3453..5105)
                     /gene="fbp54"
                     /locus_tag="VLL59_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HER6509482.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRLQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIDPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            5459..6457
                     /locus_tag="VLL59_001364"
     CDS             5459..6457
                     /locus_tag="VLL59_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HER6509483.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            6802..7671
                     /locus_tag="VLL59_001365"
     CDS             6802..7671
                     /locus_tag="VLL59_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509484.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFLIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERYFKGVRLTR"
     gene            7668..8426
                     /locus_tag="VLL59_001366"
     CDS             7668..8426
                     /locus_tag="VLL59_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509485.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            8630..10291
                     /locus_tag="VLL59_001367"
     CDS             8630..10291
                     /locus_tag="VLL59_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HER6509486.1"
                     /translation="MTDIKMIALGGVRECGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGDVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            10424..11209
                     /locus_tag="VLL59_001368"
     CDS             10424..11209
                     /locus_tag="VLL59_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HER6509487.1"
                     /translation="MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFEDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEQRFS"
     gene            11239..11565
                     /locus_tag="VLL59_001369"
     CDS             11239..11565
                     /locus_tag="VLL59_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509488.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            11611..13518
                     /locus_tag="VLL59_001370"
     CDS             11611..13518
                     /locus_tag="VLL59_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HER6509489.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGEIVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQETLME
                     EWETIAEQIES"
BASE COUNT         4218 a         2315 c         2904 g         4261 t
ORIGIN      
        1 agatgttatg gcagaacttt ctgagtctga ataattttag ttcaccaaag aatcaagaaa
       61 gaaccattgg ggcaaaattg gggcataagt ttagaacttt tgtcgtttct tgtgtcgata
      121 caataccggt ttaatactaa caaatgcttt tattatcgac tttgtaacca ttattgttcc
      181 ttgtgttttt tcgggaataa actcaagaag tgattaaata aaacattaaa gaaccttgtc
      241 atatcaatta tcgttgatat gacaaggttc ttttgatagt ttaaattgat gtttgtcatt
      301 gtaggctctt atctacactt ttttaaggca tctttagaag gttttgagcg tgactaagta
      361 ttcacacttt gactcataaa atgatagcat attttctaga gattggtata atagaaacaa
      421 agatggaaag gaaagagata gatgactcaa ttagcaacca tttgttacat tgataatggc
      481 gattctttgc tattattaca ccgcaataaa aaagaaaatg atgtccacaa aggcaagtgg
      541 atttcagttg ggggtaagct cgaggctggt gagaccccag atgagtgtgc ccgtcgtgag
      601 attttagagg aaacccattt gactgttaca gagatggcct ttaaaggaat cattactttt
      661 ccagaattta cccctggtca tgactggtat acctatgttt ttaaagtaac aggatttgaa
      721 ggagacctca tttccgatga agagtcacga gaaggaacct tggaatgggt accttacgat
      781 caagtgttgg aaaagccaac ttgggaaggt gattatgaca tttttaaatg gattttagaa
      841 gaccgtcctt ttttctctgc caaatttacc tatgaccaaa acaaccaact catggataaa
      901 tctgtgacct tttattgatt tacccaggtt accagtaaaa cttatcattt tcccaaagaa
      961 aggaacccta tcttaatgcc cttaatacct gacaagtcta gaacagatag cttattttac
     1021 aaatggtttt taaataatca agctaccatg gctttagtaa taacactttt agccttttta
     1081 acgatttttg tttttactaa aatctctttt ttatttatgc cagtgatttc tttttttgcg
     1141 gtcatcatgt tgcccttagt tatttcgacc attctgtatt atctgaccaa acccttagtt
     1201 gaccttatta atcacttggg cccgaatcgt accacctcta tttttattgt ttttggtttg
     1261 attaccttac tttttgtctg ggcgatttca ggctttgttc ccatggtaca gacccaactt
     1321 accagtttta ttgaggatct gcccaaatat gtgggcaagg tcaatgaaga agccaataaa
     1381 cttcttgaaa atgaatggtt agtcagctac aagccccaac tccaagacat gcttacccat
     1441 acaagtcaaa aggctttgga ttacgcgcaa agtttttcaa aaaatgctat tgactgggct
     1501 ggtaattttg ctggtgccat tgctcggatt accgtggcta ttattatttc gccctttatt
     1561 ctcttttatt ttttacgaga cagtagccac atgaaaaatg gccttgtgaa tgtcttacct
     1621 ctcaaattac gggtgcctat ggttcgagtc ttgggagata ttaacaagca attatcaggc
     1681 tatgtccaag ggcaggttac ggttgcaatt gttgtcggct ttatgttttc tatcatgttt
     1741 agtcttgtgg gactgaaata tgccatcact tttgggatta ttgctggctt tcttaacatg
     1801 ataccttact taggaagttt ccttgccatg atacctgttg tgattatggc tatggtacaa
     1861 ggcccattta tgttggttaa ggtgcttgtt atctttatga ttgagcaaac catcgaaggc
     1921 cgttttgtgg caccgcttgt tcttggaaat aagctgagca ttcatccgat tacgatcatg
     1981 ttcttattgt tgactgcagg atcaatgttt ggcgtttggg gtgtcttctt agtcatccca
     2041 atctacgctt ctgtcaaagt tgtgattaaa gaattatttg actggtacaa aaaagttagc
     2101 ggtttgtatg acgaagaagt attggtgatt gaggaggtta aggaccatgt taaatagtga
     2161 aaaaatgatt gcttccttgg atcagcaaga cctagcgcac gctgaaaaat atttccaaaa
     2221 agctttaaaa gaagatgatg cagatagttt aatcgcctta ggagaatact tagaaagtat
     2281 aggttttttg ccacatgcca agcgtattta tttgcagtta gctgatgatt acccagaact
     2341 caatataaat ttagctcaga ttgcagcaga agacgacgcc attgaagaag ctttcttgta
     2401 tttggataag gtttcaaaag atagccccaa ttatttgtca gctctcttag taatggctga
     2461 cctctatgac atggaaggac tgacagaggt ggcgcgtgaa aaattgcttc aagcagtgag
     2521 catcagccca gagccattgg tcatttttgg tttggcagaa attgacatgt ccttgcagta
     2581 ttttaaagaa gctattgatt actatgcaca gttagacaat cgtcaaatcc ttgaattgac
     2641 aggtatttcc acttatcaac gcattggacg agcctatgct agcttaggga aatttgaggc
     2701 agccatcgaa ttcttggaaa aggccgtggc cattgaatac gaagatgaaa ctgtttttga
     2761 attggcgacc ctcttgtatg accaagaaaa ttatcaaaaa gctaatcttt actttaaaca
     2821 gttggaaacc atcaatccag attatccagg ttatgaatat ggttatgctt tgagtcttca
     2881 tgaagagcat aagacgtcag aagctttgcg cttggttcaa cagggcctac gtaaaaatgc
     2941 atttgacagt caattattat tactagcatc gcagctttct tatgaattac acgataggca
     3001 gaatgctgaa aattacctgc ttcaagcaaa ggaaatagct gttgatgacg aagagattct
     3061 catgcgttta gtgacccttt attttgatgc cgagcgtttt gaggaggtta ttgctcttaa
     3121 tcgtgagacg attgataatg tcttaaccaa atggaccatt gcaaaggctt accacgcctt
     3181 ggaacaagaa gaagttgcct tggctcttta taatgagatt tcggctgatt tggcagaaaa
     3241 tccggagttt ttacaggatt atgcctattt attaagggag tttggccagt ttcacaaggc
     3301 tatccaaatg gctaccgctt acctcagaca agtgcctgat gatgtgaata tgcaagactt
     3361 tcttgaccat atcaagcacc aacaatcaga ataaaaaaac agttctccta ggggaaataa
     3421 ctttcctagg agagctgttt tttagttgct tatcaggata atttcataga gagaattttg
     3481 gcttggtcag gagtaacccg taaagttttt tgaccagtat aagtcacaaa tcctggcttg
     3541 gcgccactag gtttgtgtaa ttttttagct tcaatcatat cgacctgaac gagatttgat
     3601 aacctagctt tcgaataata agcagctagt tcggcagcat cagttttaac ctcgtcactt
     3661 gggtcaagat tgtctttgat gatgacatga cttccaggga tatccttagc atggaaccag
     3721 agttctcctt ttttagccat tttaaaggtg agttcttcat tttgcaagtt attgcgtccc
     3781 accatgagaa tggtttttcc atctgaagcc aggtactgct caggcttttt acgtttatgg
     3841 cgtttgtctc tttggcgact tttcaaaaag ccagcctgat ataattcttc gcgaatatct
     3901 tcgatgtcgt cgatacttgc ttgagataaa ttgtagtcca cgctctcaaa gtaagtaata
     3961 ctttgcttgg tatcggcaat caatccagat aagtgtttga cagcttcttt tagcttttgg
     4021 tattttttaa aataacgttg agcattttga tttggtgtca gagccttgtc taaggcaatc
     4081 tcaatttttt cccctgtata ataattgtct aaaatcacag agtcttggtt gtttgggacc
     4141 agactgaggt aggtggtcaa taattctcct ttttgacgga ataattcagc attttcagtg
     4201 gctagcagct cagcttcttg cttacttagc ttgttgcgat ttttgtccag ttcagtttgc
     4261 acacggtgga tcaaatcact ggcttgctga ttgatacggt cgcgctcagc cttgtcttga
     4321 taaaagtggt caagcatgtc agacaaagtc tcaaacgtcg catgactatc tgagaaaaga
     4381 acaggcgcaa aagaagctgt ggtcagattt gcctgagtag gtctagcaaa aaactcacgg
     4441 aaccgtttta atttgtctgt ggtcagaagc tcggccaatt cttttgcggt gtctcgccct
     4501 aagccttgaa aatgctgttg caagctttta actgttagtt cttgtgtttg gaggatttca
     4561 aatagaggaa catctgtaat tgtaaaagga ttaacagcag ctgttttagg aggatcaatg
     4621 taggtagagc caggtaaaat ggtgcggtaa gagttttgtg aaaagccaac atgtttaatg
     4681 gattcgatga ttttattttc tgcacggtcc accaagatga tattactgtg cttccccatg
     4741 atttcaatga ttagggttgc ctgaatagca tctccgattt catttttatt agataccttg
     4801 atttcgataa tgcggtcatt atcaatctgt tctaactgct caatgactgc accctggagg
     4861 tatttacgca taatcatggt aaaggtatta ggtacctgag gattttgaaa gtccgcttgg
     4921 gtaatttgaa gtcgtccaaa aacaggatgg gcagacaata gcaatttata attcttgcga
     4981 tggttacgaa tggttaagac aagttcccgt tcaaagggtt gattgacctt ttggatacga
     5041 ccgtaaagca agttctcttt taattcgttg gttaaatggt gtaagaaaaa gccgtcaaaa
     5101 gacatggttt ctcctttctg aattctaatc tcttcattat accacaaata cttgactaaa
     5161 aatatggacg aaagagcttg caattttttt gatttaggtt ataatgttaa aaaaacgaga
     5221 aaggaagtca atgatggtaa aaacacaaca cttagcaaat tggcaaagct ggcatagata
     5281 agttgtgttt atgaattggc atagatacga cttttagagt acttctaaaa agatatctat
     5341 gcgctgacat tggatttcac aagagcgcct agtaatcatt actaagtgct ttttcttttg
     5401 agaagtattc tcatcatcaa cgttttaaag agattgacat gaaatgtgag gaattcagat
     5461 gaaaaacaag agtttaatag ctaccctcct tgttttaact gtaatagtga taggctctct
     5521 attatcaaaa ggagtatcaa aggaaaaccg tgatttagct aaccaacaaa acattacaat
     5581 tggcatctta caattcgtta ctcatgaggc tcttgatgat attaagcgag gtattgaaga
     5641 tcaactcaaa aagcagatgc ctcaaaaaca aaatgtagtg attaaggtta tgaatgctga
     5701 gggggatcag agtaaaatcc aaacaatgag taggcaatta gtgcaatcag gaagtgatat
     5761 cgtgattggt atcgcaaccc cggcggcgca aggcttagca gctgccagca aggatatccc
     5821 agttgtcatg tcagcagtat ctgatccagt aggatctaga ttagtgatgc aattggatca
     5881 acctgaagct aatgtaactg gtctatctaa taaagtgcct gttaaacaga caattgattt
     5941 aatgaaaaag ctgacaccac atgttaaaac agttggaatt ttatatgcaa gtaatgagga
     6001 taattcctta tctcaagtta aagagtttag gcggttagct cgcaaaaagg gctatcaagt
     6061 tatttcatac gcggttcctt ctactaacga agttcctgcc acgatgtcag ttatgttagg
     6121 taaagtagac gcggtattta tcccccaaga caatactata gcaagtgcat tttcatcagt
     6181 catgacaacc agtaaggctg caaagattcc tgtctacact agcgttgatc gaatggttga
     6241 aaaaggtggt ttggcagcca tttctcaaaa tcagtacgat ttgggagttc aaacagctaa
     6301 tcaggtatta aaattaatca aaggaaagcg tgttgtagat gttcctgtca aagttgtgga
     6361 tattggtcaa ccgctaatta ataagaatgt agcagcagaa ttaggtattg ctattaacag
     6421 ggaagatttt ccttcagctt cttttattga gaattaatac aatgacatgt gatataaaag
     6481 gtcaagaaaa aaccataaaa aacaccctca ctgagatgaa tttggatgcc aagtcagaca
     6541 atcgtcttga ggatgtaagg gttattttta tcatttttag ttttaaaatg ctctatttta
     6601 gacacgtaaa aaatcttgcc ttttgagtaa gtttaaacat gattctcaac ttttttgttt
     6661 tctgtcttag tttcgttaaa gtgattggaa aaaagactaa gccacggtgc tgaactaagt
     6721 ataaaacaaa tctaaaaatt aatgtaaaga aagggtttat actggcgaga gttacccgct
     6781 aatataaata tgaggaaaaa tatgattatt tcatcagttt cacaaggcct tatatgggga
     6841 gttttaggat taggaatcta cctgaccttt aggattttaa acttccctga catgactaca
     6901 gaaggttctt ttcctttagg aggagctgtt gcggtcaccg ctattagctt agggtggaat
     6961 ccatttctat caaccttact tggtatgtta tcaggtgctt tagcaggttt tttaacaggg
     7021 ctgttatata cgaaaggaaa aatgccaaca cttttagctg gaattttggt gatgacgtca
     7081 tgtaactcca ttatgctaat ggtaatggga agagcaaact tgggtttaca tgatcataaa
     7141 cgtattcagg attgtttacc ttttttaatt gatttaaata gccttttaac aggtctgata
     7201 actgttgtga ttgttattag cgttttgatc tatttccttt acactaatct aggtcaagct
     7261 tatatcgcta cgggagacaa taaagatatg gctaagagtt ttggtattaa cacggattgg
     7321 atggaagtta tgggacttgt ggtttctaat agtttaatag ctttatcagg tgctctagtg
     7381 agccaacaag atggctatgc agatgtctca aaagggattg gagttattgt tattggtttg
     7441 gcgagcataa ttgttggtga agtactatac tcaactggac tgactctttt agaacgtttg
     7501 attgctattg taataggctc gattctttat caatttttaa tttcagtagt tattacgcta
     7561 ggttttaata caagttattt gaaattaatt agtgctcttg ttttagcact gtgcctcatg
     7621 ataccagtgg taaaagagcg ctactttaag ggagtgaggt taacacgatg acaaaaatta
     7681 ttgaattgat caatgcaaca gttgacgtag ataatggttt tgaagatgct aaaacaatat
     7741 tggacaatgt gacactaact atctatgaac atgatttttt aactatttta ggaggaaatg
     7801 gagctggaaa atcaaccctt tttaatgtaa ttgcaggaac gctaagtttg acacgggggc
     7861 aaattaggat tcttggtcag gatgtgacgc attggccggc agaaaaaaga gctctttacc
     7921 tatcgcgagt ctttcaagat cccaaaatgg gaacagcccc tcggatgaca gtggctgaaa
     7981 atctcttaat cgcacgtcaa agaggagaaa aacgctcctt ggcttctcga aaaataacag
     8041 agcacttagc tagttttgag gatttggtta aacgaacagg aaatggccta gaaaagcatt
     8101 tagaaacacc agcaggtctt ttgtctggtg gacaaagaca ggctttaagt ttattaatgg
     8161 caacgttgaa aaagccagct ctcttattat tagatgaaca tacggctgcc cttgacccta
     8221 agacgagtca atctttaatg caattgacag atgagtttgt gacaaaagat ggcttaacag
     8281 ctttgatgat tacccaccat atggaagatg cattaactta tgggaatcgt ctgattgtaa
     8341 tgaaagatgg aaacattatt aaagatttaa atcaaatgga aaaagaacaa ctgacgatta
     8401 ctgactatta ccaactattt gattaatcaa cgatctaaat cattgactaa taataagtca
     8461 gtgatttttt gatttccata ctgaaaataa tctgaaagta tcaaggctat ttagagaaaa
     8521 aacgcctcaa atatgatata ctatagaaga tagtagcata gctacataac agtaattcga
     8581 cttacgttgt aaggaccgtt tgtaataata aaatatttaa aggagtatca tgactgatat
     8641 taaaatgatt gccttgggag gggtccgtga atgcggaaaa aacttctatt tggtagaaat
     8701 taacgattct atgtttattt tagacgcagg gctcaagtac cctgaaaatg agcaacttgg
     8761 ggtagattta gtcatcccca atttagatta tgtaattgaa aacaaaggta aagtacaagg
     8821 gattttcttg agtcatggcc atgctgacgc cattggagcc cttccttatt tgttagctga
     8881 agtatcagct cctgtatttg gatctgaatt gactattgaa ttagccaagc tatttgtgaa
     8941 aagtaataac agcactaaga aatttaataa ttttcatgtg gtagacagtg atactgaaat
     9001 tgaatttaaa gatggcctag tttcgttctt tagaacaacg cattcaatcc cagaaagtat
     9061 gggtattgtt attggaacag ataaaggaaa cattgtttat accggtgact tcaaatttga
     9121 tcaagcagca agagaaggtt atcagacgga tttgctacgt ttagctgaga ttgggaaaga
     9181 aggggttcta gctcttttat cagattcagt caatgcgaca agcaacgatc agattgccag
     9241 cgaatctgaa gttggtgaag aaatggacag tgttatctct gatgctgatg gccgtgtcat
     9301 tgtagctgca gtagcctcaa atcttgttcg gattcagcaa gtatttgatt ccgccactgc
     9361 ccatgggcgt cgtgttgttt taaccggaac agatgcagaa aatattgtca gaacagcttt
     9421 acgtctagaa aaattaatga ttacggatga gcgtctttta attaaaccca aggatatgtc
     9481 taaattcgaa gaccatgaat taatcatcct tgaagctggt cgtatgggtg agccaattaa
     9541 tagcttacaa aaaatggcag cgggacgtca ccgttatgtt caaatcaaag aaggagacct
     9601 tgtttatatt gtaactacac caagtacggc taaagaagct atggtggcgc gtgtagaaaa
     9661 cttgatttac aaggccggtg gttctgttaa attaatcact caaaacttac gcgtgtcagg
     9721 ccatgctaat gggcgtgatt tgcaactatt gatgaatttg ttaaaacccc agtatctttt
     9781 tccagtgcaa ggagaatatc gtgatttagc tgcccatgca aagctagctg aagaagttgg
     9841 tatttttcca gagaatattc atattctgaa gcgtggcgat atcatggtgc ttaatgacga
     9901 aggttttctc catgaaggag atgtacctgc cagtgatgtc atgattgacg gtaatgctat
     9961 cggtgatgtg ggtaatatcg ttttacgaga ccgtaaagtc ttgtcagaag atggtatttt
    10021 cattgttgct attactgttt ctaaaaaaga aaaacgcatt atttctaagg ctaaagttaa
    10081 tacgcgtgga tttgtgtatg tcaagaaaag tcatgatatt ttaagagaaa gtgcagaatt
    10141 agttaataca actgttggca attacttaaa aaaagatacc tttgactggg gcgaattaaa
    10201 agggaatgtc agagatgatt tgtctaaatt cttatttgaa caaaccaaaa ggcgcccagc
    10261 gattctgccg gttgtgatgg aagttcgtta gtgaaaatag gaaggttagg caaaaactgc
    10321 ctaccttctt tgattttaac aactggtaaa ccaggaaact gttcacccaa aaatacagta
    10381 gatttacgtg ataggattat tttggtataa aggagtgtaa tgaatggcaa gtattgcaat
    10441 tgaataccat tcggtagttt taggaatgga gcgtaaggta aatgtgattt atcctgacca
    10501 gtctgaaatc cctaaaaaag atcaagggga taaggatatt cctgttttat atttgttaca
    10561 tggtatggga ggcaatgaaa actcttggca aaaacgaaca gctattgaac gcttgttgcg
    10621 gcataccaat ttgatagtcg ttatgccttc gacagaccta ggttggtata cagacacggc
    10681 ttatggactt aactattatc gggcgttgtc acaagagtta ccgcaggtct tagcagcttt
    10741 ctttcctaat atgacccaga aacgagaaaa aacctttgtt gctgggctct ctatgggtgg
    10801 ctatggtgcc tttaagtggg cactcaaaag caatcggttt tcttatgcag catcgttttc
    10861 aggagctttg gatttttctc ctgagacctt gcttgaggga aacctgggag aattagccta
    10921 ttggcagggc gtttttggcc agtttgagga ccctgacctt gataagcatt accttaaaaa
    10981 tatggtggca gaaagtgatg gaaaaaccaa attttatgct tggtgtggct atgaggattt
    11041 tctttttgcc actaatgaaa aagctattgc tgattttcag gctcaaggtc ttgacattga
    11101 ttatcataaa ggtcatggta aacatgagtg gtactattgg aaccagcaat tagaagtcct
    11161 gttagagtgg ttaccgataa actaccaaaa agaacaaagg ttctcttaac catttcctag
    11221 tacaacatga ggtgacaaat gaaacaatta ctggcgatca ttttgtggct acctaagcta
    11281 atagtgaaaa tgttttggca tcttatcaaa gggtttttac aaactatctt attagtaacg
    11341 attattatta tagggctgat gtattattct aatcacagtg attccgtttt agccaataag
    11401 atctcgatag ttactgagca agtggtgcaa atttttgata tcttaacaca aaagccatct
    11461 gcaaagacgc gtcatgggag tggtaatagt cattccactt tccttgttag cgctaaagaa
    11521 ggtaatcaac gacttaaaaa gagttcgatt tcttttggaa actaggctga aaatgtcctc
    11581 aaaagggcat ttttttgtta gaatgaaagt atgattattt tacaaggaaa caagttagaa
    11641 cgctctttct caggagatgt tctttttcaa aacatatcac tgcaagttga tgaaagagac
    11701 agaattgcat tagtagggcc aaatggagct ggtaagtcaa ccttactcaa gctattggtt
    11761 ggggaagaaa ccccaacgag cggagaagtt aatactaaaa aagacctaac cttgtcttat
    11821 ctggctcaaa atagccgttt tgaatcagat caaacaatat atgaggaaat gctcaaggtt
    11881 ttcgaagcat tacgccaaga tgaaaagcgc ctgcgtcaga tggaaatgga tatggcaacc
    11941 gtttcaggtc aagatttaac ccgactgatg acagattatg atctgcttac agagcatttt
    12001 cgtcagcaag gcggctttac gtatgaatct gacatcaaag ccattttaaa tgggtttaag
    12061 tttgatgaga gcatgtggca gatgactatc gctgagctgt cagggggtca aaatactcgt
    12121 ctggccttgg ctaaaatgct tttagaaaag ccagaactat tggtccttga tgagccaaca
    12181 aaccacttag atattgaaac cattgcctgg ttagagaact acttggccaa ttatcaagga
    12241 gctctaatca ttgtgagtca cgaccgttat tttttggata aggtggcaac agtgaccttg
    12301 gatttaactc ctcatggatt ggatcgctac gttggcaatt attctcgttt tatgacctta
    12361 aaagctgaaa aattagtagc cgaagaaaag cagtttgaca aacagcaaaa agaaattgcc
    12421 aagttagaag attttgttca aaaaaatatt gtcagggctt caactacaaa acgtgctcaa
    12481 gcgagacgta agcaattgga aaaaatagaa cgcttagaca aaccgactag tgctagaaaa
    12541 tcagctcaca tgacttttca ggcagataag ccgtctggca atgtggtgtt gacggttgaa
    12601 aaagctgcta ttggttataa ccaacatgtc ttatctgaac ctattaacct agacgttcac
    12661 aaattagatg cgattgctat tgttggtcca aatggtattg gtaaatccac tctgattaaa
    12721 tctgttattg gacagattcc tttcatcaaa ggagaagtga aatacggtgc caatgttgaa
    12781 ataggttact atgaccaaac ccaatcacat ttgacgtcta gcaacacagt tttggaagaa
    12841 ttatggcagg atttttcaac tacgccagaa gtcgatatca gaaaccgatt aggggctttt
    12901 ctcttttctg gagatgatgt caaaaaatcg gtggctatgc tgtcaggtgg agaaaaagcc
    12961 cgtctgcttc ttgcgaagtt atctatggaa aacaataatt ttcttgttct ggacgagccg
    13021 actaaccacc tagacattga cagtaaagaa gtgctagaga atgccctcat tgactttgac
    13081 ggcaccttgc tttttgtcag ccacgaccgc tatttcatta atcgtttggc aactaaggtt
    13141 ttggaaatta ccgaaaatgg ctcaaccctt tacttaggtg actatgatta ttaccttgag
    13201 aaaaaggcag agctagaaga actagcccgc ctagcagcag gagagatagt tgaggaaaca
    13261 aaagaagcct ctgccactga ttatcagcta caaaaagcta atcaaaaaga gcgtcgtcgc
    13321 ttgacccgcc gatatgagga gattgaagca agacttgaaa ccattgaaga gcgcattggt
    13381 gctattcaag aagacatgca tgcctccaat gatacggcgc agttaatcgc ttggcaaaag
    13441 gaatgggacc aattggatca agaacaagaa actcttatgg aagaatggga aaccatcgct
    13501 gaacaaatag aatcataaaa ataagcttta gcagttttgc taagcttatt tttatcgctt
    13561 tgctacttgt ttggaggtgt gaaagaggtt ttaaaatgat atgtttttta tgtcaaggtc
    13621 ggtaaaacgt gaaactgtta tatagtattt ttaaattttt tagtacagtt ttgtttgtaa
    13681 tttcacaaac tattgcat
//
LOCUS       DAUNLR010000046        13325 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUNLR010000046 DAUNLR010000000
VERSION     DAUNLR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13325
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.046"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..853
                     /locus_tag="VLL59_001371"
     CDS             <1..853
                     /locus_tag="VLL59_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HER6509490.1"
                     /translation="DLKPFQVKDLVSGHLERIQEEVEKKYPNAGFNSDKYNGLKESNS
                     LLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPDFLANSDRAAYDNYRTYKEQHPKKLV
                     ALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIGSKVVNNENLTKRVSDAGHEIANHTW
                     DHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPRYLRPPYGATNATVQQSSGLTQMLWT
                     VDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDIHQTTINALPTVMEYLKAEGYECVTV
                     SELYAHQ"
     gene            complement(964..2049)
                     /locus_tag="VLL59_001372"
     CDS             complement(964..2049)
                     /locus_tag="VLL59_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6509491.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2147..2773
                     /gene="udk"
                     /locus_tag="VLL59_001373"
     CDS             2147..2773
                     /gene="udk"
                     /locus_tag="VLL59_001373"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HER6509492.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            2853..3116
                     /locus_tag="VLL59_001374"
     CDS             2853..3116
                     /locus_tag="VLL59_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HER6509493.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(3169..3978)
                     /locus_tag="VLL59_001375"
     CDS             complement(3169..3978)
                     /locus_tag="VLL59_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HER6509494.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFVAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVIALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            4123..4620
                     /locus_tag="VLL59_001376"
     CDS             4123..4620
                     /locus_tag="VLL59_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HER6509495.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            4620..6290
                     /gene="dnaX"
                     /locus_tag="VLL59_001377"
     CDS             4620..6290
                     /gene="dnaX"
                     /locus_tag="VLL59_001377"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HER6509496.1"
                     /translation="MYQALYRKYRSQTFDKMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTASYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFGFLLDKINTIDD"
     gene            6385..6588
                     /locus_tag="VLL59_001378"
     CDS             6385..6588
                     /locus_tag="VLL59_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HER6509497.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
     gene            complement(6563..7504)
                     /locus_tag="VLL59_001379"
     CDS             complement(6563..7504)
                     /locus_tag="VLL59_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HER6509498.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFENGDFQTLRSGEISLSSWEN"
     gene            7708..10065
                     /locus_tag="VLL59_001380"
     CDS             7708..10065
                     /locus_tag="VLL59_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HER6509499.1"
                     /translation="MKTKKVIILVGLLLSSQLTLISCQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKASILVNHDGHLHPISFADLRQGGWAHVADQYDPAKKAETHHTPELSE
                     REKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIP
                     DPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDLNKMKEWL
                     ATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGV
                     TDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLPDLKF
                     LVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVDLATL
                     QAPKLETLMVNDTKVSHLDFLKNNPNLSINRAQLQSLEGIEASSVIVRVEAEGNQIKS
                     LVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNID
                     ISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAKESAQEAS
                     ESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            10602..11798
                     /locus_tag="VLL59_001381"
     CDS             10602..11798
                     /locus_tag="VLL59_001381"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HER6509500.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            11972..13231
                     /locus_tag="VLL59_001382"
     CDS             11972..13231
                     /locus_tag="VLL59_001382"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HER6509501.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT         4228 a         2310 c         2788 g         3999 t
ORIGIN      
        1 cgacttgaaa ccgtttcagg taaaggatct agtatcagga catttagaaa gaatacaaga
       61 agaagttgaa aaaaaatatc caaatgctgg ttttaatagc gataagtaca atggcttaaa
      121 agaatctaat tctttattaa gcgatggctt tgaggtaaaa tcgggaaacc ttatttttga
      181 taaaaagcta acgatacctt tgacgacatt atttgatgtt attaatccag attttttagc
      241 aaatagcgat agagctgcgt atgataatta taggacctac aaagaacagc atcccaaaaa
      301 actagttgca ttaacgtttg atgatggtcc agatccgacg acgactcctc aagttttaga
      361 tattttggca aaataccagg ctaagggaac tttctttatg ataggttcaa aagttgtgaa
      421 taatgaaaac cttactaaac gtgttagcga cgctggccat gaaattgcta atcatacttg
      481 ggatcatccc aatctgacta atctttcagt cagcgagatt caacatcaag ttaatatgac
      541 gaaccaggct attgaaaaag cttgtggcaa gaaacctcgc tatttacgcc ctccatacgg
      601 agctacaaat gcaactgttc agcaatcctc aggattaaca caaatgcttt ggacggttga
      661 tacaagagat tgggaaaatc atagcactga tggcattatg actaatgtca aaaaccaatt
      721 gcaaccggga ggagttgttt taatgcatga tattcatcaa acaactatca atgctttgcc
      781 gacagttatg gaatatctaa aagcagaagg atacgaatgt gtgactgtat cagaactcta
      841 tgcgcatcag taagtaatat cgttatgttt ctttagaatt gatatactaa acaatccaat
      901 tacttcaaaa gtaattggat tgttgttttt agtagccctt gattaagttt tgttttttaa
      961 caactagttg atgaaatgaa gttgctgatt tttgagggag atttcagaga ctttagcaaa
     1021 ttttttcaat tttttgaggt cttcagggtg gctaacaaag gtaataacga taccagattt
     1081 tcccatacgg ccggttcgtc cagctctgtg agtgtaattt tccttatcac gagcaacatc
     1141 aaaatgaatg acatagtcaa gattatcaat atcaatgccc cgagcaacaa gatccgtagc
     1201 taacaataag gagagttggt gggatttgaa tttttcgaga atggttttac ggaatttgac
     1261 attaatgtca ctcgctaagg aaaccgcagc agctccatta tactggagac gttcttccgt
     1321 agcacccaaa tcagataaac tgttgaaaaa gaccaaagct ctaaaatgag gaatattagc
     1381 aaattttcgt aataaatcgg tacgttcgcg cttgtcaacc atgaggtaaa aatgctgaat
     1441 agcatcgttg gtttgctctg aaagatcgat gcagaatgta tttggagcta aggaagtttg
     1501 atccacctta ttagtagcac tcatgtatac catttgatga tctcgaggaa catagtggct
     1561 aattttttga acaaaatcat attgggaatc acctaataat tcgtcatatt catctaaaac
     1621 aatggtgttg acagacatca tcttgatttt ttttaattta atcagttcaa aaatgcgtcc
     1681 aggggttcca atcaggattt caggaccttt tttgaggcgt tcgatttgac gtttttgact
     1741 ggttccagaa ataaagagtt gtgccgttaa gcctagtggc tgtgcccaat cctttgtgac
     1801 ttcaaaaatt tggccagcta attcggtatt aggggctaaa atgagtagtt gttgggactt
     1861 tttaggcgtc agtgccaata gactaggaaa gacataagct aaggtcttgc ccgtcccagt
     1921 agggctaata ccaaggaaat ttttaccatc aacaataggt tgaaaggcct gttcttggat
     1981 tggcgttaaa tgggtaaatg caacttggtc aagtttttct tgccattgag ggggaaattt
     2041 agtgatcatg cgtcttcctt ttactattgt ttctatattc attatagcat tatagtctca
     2101 attttggtaa aatagtgaga aagacttttt agatttggag tttaaaatgc ttaaaaaacc
     2161 gattattatt ggtgtaactg gtggttcagg tggcggtaaa acaagtgtgt cacgcgctat
     2221 tttggacagt tttccaaatg ctcgtattgc gatgattcaa cacgattctt actataaaga
     2281 tcagtctcac atgagttttg aagaaagggt caaaaccaat tatgaccatc ctctagcttt
     2341 tgatacagat tttatgattc agcaactaaa agaattatta gctggtagac ctgtagatat
     2401 tcctatctat gattacaaaa agcatacccg cagtaatacg acctttcgtc aggatcctca
     2461 ggatgttatt attgttgaag gtattcttgt cctagaagat gagcgtttgc gagatttgat
     2521 ggatatcaag ctctttgtag acacagatga cgatattcgt attattcgtc gtattaagcg
     2581 tgacatgatg gaacgtggca gaagcttaga aagtattatt gatcagtaca caagcgtggt
     2641 aaagcctatg tatcatcagt ttattgagcc aagtaaacgc tatgctgata ttgttattcc
     2701 agagggagtt agtaatgtcg ttgctattga tgttattaat agtaaaattg cgagtattct
     2761 tggagaagta tagtgaaagt ggctgagtag attatttaaa tctgctcttt tattgttgtg
     2821 ctcttcctag agaaagggat cataaaatag aaatgttatt aatttggctt ggattactat
     2881 ttgtttggaa tgaactcgtg tttgtcatat atgcttttga taaaagaaaa gccataaaaa
     2941 agaaacggcg tattagtgaa agaaacttat tagtgataac agttttgttt ggaggttttg
     3001 gagcattact tgcagctaaa aagtaccacc ataaaaccag aaagtggtac tttgtcatca
     3061 cttggtatac tagtattttg ttgacattac tagtaactta tatctttatg aagtgagtca
     3121 cttaaaagac ccttaatcag tattatttag tcaaggctct tttatagttt aaaaaagcac
     3181 atcatcgtca agagtgttga ttttttgaaa aagatcacca aagattaaaa ggattaatgt
     3241 tcctagtaaa actgtcatgc caggaatgct tgttagagga gagttccaga tgaaatgtag
     3301 aaccagagga cttaataacc agaaaatttg ttgctgtttt gaaaaaaggt tagaaccctt
     3361 taataataag tatgctccaa tggtaaaaat agctgtatgt acccaatgtg aagtcacagc
     3421 agtgctaata cgttcaatag cagtcggtac gagactatct atagattttg cttgaatcaa
     3481 ataacggata tcttctgtta gttgaaagcc catgccagaa agtaaagcaa taactaattt
     3541 ttctttaaga gtaagtctag gaaataaagt aattactaaa atagccgaag aagccttaat
     3601 gggctcttcg acaatagggg cagttaaagc atctccccaa agctttaaag cgtctttaga
     3661 agggatgatg tatgaccaaa attgtcctac gagatggttc ccacaagaag ctaaaaaacc
     3721 tgaaatataa agtccgctaa gacagctaac aataataacg ttcaggttca tatgaaattt
     3781 tttacttaaa taaaaaatag ctgctacaaa tggaattaag taaatgccta atagactaat
     3841 ggttagtatt agagcaaaag cttctttaaa ggaaaggttg ttagcagtca gtcctaacaa
     3901 ttcaagttca ataccattta aaactaaagc aataaaaaga ccgtatcgta accatttctg
     3961 ttgagtgatt tgtttcacga aaacctccta atattaagat gatattaata atattgaaaa
     4021 ttatatcata aacaacctca aaaaccattt taaaaactga ctgaagcgaa agatagtcgt
     4081 aaaaaatact cgaatagacc cagatatgct ataataaaag gtatgaataa gtctaaaaaa
     4141 attgagcaat accaactaat gatagcgcag gcaaaagagc tgtttgcgaa tgaatcaaat
     4201 gctttggcta atttgtcaaa tgccagcgcc ctgttaaaca tgacactacc caattctgtt
     4261 tttgcgggat tttacctttt tgatgggcag gaattaattc ttggcccttt tcaaggtagg
     4321 gtttcttgcg tccatatcaa gcttggtaaa ggtgtttgtg gcgaatcagc tcagtctcgt
     4381 cgaaccatta ttataaatga tgtgaagcag catgccaact atatttcctg tgatgcggca
     4441 gccatgagtg aaattgttgt gcctatggtg aaagaaggcc atttgattgg ggtgctggac
     4501 ttggattcta gccttgtagc tgattatgat gaggttgatc aagaatactt agaggccttt
     4561 gtggacctat ttcttgaaaa gaccacgttt acctttaaca tgtttggagt taaaaactga
     4621 tgtatcaagc tctttatcgg aaataccgga gccaaacgtt tgacaaaatg gtgggacaat
     4681 cggttatttc cacaacttta aagcaggcag ttgaatctgg caagattagc catgcttatt
     4741 tattttcagg tcctagaggg actgggaaaa caagtgcggc aaagattttt gcaaaggcca
     4801 tgaattgtcc taaccaagtc gatggtgaac cctgtaatca atgcgatatt tgccgagata
     4861 tcacgaatgg aagcttagaa gatgtgattg aaattgatgc tgcctcaaat aatggtgttg
     4921 atgaaattcg tgacattcga gacaaatcaa cctatgcgcc aagtcgtgcg acttacaagg
     4981 tttatattat tgatgaggtt cacatgttat caacaggggc ttttaatgcg cttttgaaaa
     5041 ctttggaaga accgacagaa aatgttgtct ttatcttggc aacaacggaa ttgcataaaa
     5101 ttccagccac tattttatct cgtgtgcaac gctttgaatt caaagctatt aagcaaaaag
     5161 ctattcgaga gcatttagcc tgggttttgg acaaagaagg tattgcctat gaggtggatg
     5221 ctttaaatct cattgcaagg cgagcagaag gaggcatgcg tgatgcttta tctattttag
     5281 atcaggcttt gagcttgtca ccagataatc aggtcaccat tgcaattgcc gaagaaatta
     5341 caggttctat ttccatactt gctctgggtg actatgttcg atatgtctcc caagaacagg
     5401 ctacgcaagc tctggcagcc ttagagacca tttatgatag tgggaagagc atgagccgct
     5461 ttgcgacaga tttattgacc tatctgcgtg atttattggt ggttaaagct ggcggcgaca
     5521 atcaacgtca gtcagctgtt tttgatacca atttgtctct ctcgatagat cgtatattcc
     5581 aaatgataac agttgttact agtcatctcc ctgaaatcaa aaagggaacc catcctcgga
     5641 tttatgccga aatgatgacc atccaattag ctcagaaaga gcagattttg tcccaagcaa
     5701 acttgtcagg agagttaatc tcagagattg aaacgctcaa aaatgagttg gcacaactta
     5761 aacaacaatt gtcgcagctc caatcgcgtc ctgattcact ggcaagatct gataaaacga
     5821 aacctaaaac cgcaagctac agggttgatc gggttaccat tttgaaaatc atggaagaaa
     5881 cggttcgaaa tagccaacaa tctcgacaat atctagatgc tctaaaaaat gcttggaatg
     5941 aaattctaga taacatttct gcccaagaca gagccttatt gatgggctct gagcctgtct
     6001 tagcaaatag tgagaatgcg attttggctt tcgaggctgc ctttaatgca gaacaagtca
     6061 tgagccgaaa taatcttaat gatatgtttg gtaacattat gagtaaagct gctggttttt
     6121 ctcccaatat tttggcagta ccaaggacag attttcagca tattcgtaag gaatttgctc
     6181 agcaaatgaa atcgcaaaaa gacagtgttc aagaagaaca agaagtagcg cttgatattc
     6241 cagaagggtt tggttttttg ctcgataaaa taaatactat tgacgactaa aactgaaata
     6301 cataagggta aggttttgcc cttacccacg ttttatctcg ttacttttct tcatagtaca
     6361 gtattttttt gttataataa agctatgact attcgacaat ttctttttat ggcctttgta
     6421 tgtgcctttg aaacctattt ttttaatgac ctgttgctct ctggaaatta tctcttcgcc
     6481 ttattttggg gcttgttgct ctttagggat ttaagaagag tgcataccat taaccaattg
     6541 actaaaacca ttttaaaaac ggctaattct cccaagaaga aagactgatt tcaccgcttc
     6601 gcaaggtttg gaagtcacca ttttcaaact gtacaatgag gtgtccttga tctgtgagat
     6661 caatcgcaat agcacgtttt tcttgactat tttctataaa ggtcacttgt ttattaagaa
     6721 caagtgattt ttctttgtaa actttgacat ggtccttgac aggaatagat aagaataatt
     6781 tccagatgtc aatgataagg tcattgcgcg tgatagtcgg tttttcggta aagagagaac
     6841 ctgccttttg agcaatcgct tctgggaagt cggtgacaaa aaagttgaga ccaaccccaa
     6901 taatgacatc ggtgattaaa ccagtttcaa cagaagtaat ggcttctgtc agaatccctg
     6961 caactttatg gttacctaga tagatgtcgt ttacccattt gatttctgta tcaatgcctg
     7021 ttaatcgtga gatagctttg acaatactgg aagcaaccat catcgtataa ggaggcatat
     7081 cagcataagg gacattgggt tttaggtaca tggacatgta aataccaccg gtgctagctg
     7141 aaaaaaattg ccgatcgagg cgtcctttgg cagcttcttg gctaggagct aggtaaagcc
     7201 ttggagcgct gttatgagct tcgattcctt gtttggcatc taattgggta gattggctgt
     7261 gaggggtata ggtgactggc atcccaagcc cttggctaat ggttttgggt aataaaatat
     7321 caccttgtac catgcggtag cccttgtgtt ttaaagaatc aatttgaatc ccctgatttt
     7381 cgagactttt gatggatttc caaacggatg tacgagagat actgagttga tctgctagat
     7441 attccccact gacgaagtca tcggtttgtg acagtaattg ataaattttt tctgatgttt
     7501 tcatatgtat agtatattat aaaagatctt attttcaaag gaaaagaaaa gttagttttt
     7561 ttgtgtaatg ctactaacaa cagaaactat tgtttgttga agcttcagag ctccaactcg
     7621 tcaacaacta atagttatcc taaaaagagc ttgaggaaaa acaagtgatg tgatatactt
     7681 aaccagttaa ataaaaagga gggttgaatg aaaacgaaaa aagttattat tttagttggt
     7741 ctattgttat catctcagtt gactttgata tcttgtcaat cacgaggtaa tggtacatat
     7801 cccattaaaa cgaaacaatc acgtaaggga atgacgtcaa acaaaattaa accgattaaa
     7861 aaaagcaaaa agacaaacaa gactcacaaa ggtgtggcgg gtgtcgattt tcctacagat
     7921 gatgggttta ttttaaccaa agactcaaaa atcttatcaa aaacagatca gggaatcgtt
     7981 gttgaccatg atggtcattc gcattttatt ttttatgccg atttaaaggg aagtccattt
     8041 gaatacctta ttccaaaagg agcaagttta gctaagccag ccgttgctca gcaagcagct
     8101 agtcaaggga cttctaaagt agcagatcct catcaccatt atgaatttaa cccagcagat
     8161 attgtggctg aagatgcttt aggctacacg gttcgccacg atgatcactt ccattatatt
     8221 ttgaagtcaa gcttatcagg tcagacacag gcacaagcta aacaggttgc tactcgcttg
     8281 ccacaaacca gtagccctgt ttcaacagtt acagctaatg gtattccagg cttgcatttc
     8341 ccaacctcag atggttttca atttaacggt caaggtattg ttggggtaac aaaagccagt
     8401 attttagtga accacgatgg tcacttacat cctatttctt ttgcggacct tcgtcagggt
     8461 ggctgggcac atgtggcaga tcaatacgat cccgctaaaa aagcagaaac ccatcacaca
     8521 ccagagctat ctgaacgtga aaaggaatac caagaaaaat tagcttattt ggcagaaaaa
     8581 ttggggattg atccatcaac tattaaacgt gtggaaacac aagacggtaa acttggtttg
     8641 gaataccctc accatgacca cgcacacgta ttgatgttat ctgatattga aatcggaaaa
     8701 gacattccag atccacatgc tattgagcat gcccgtgaat tggaaaaaca taaggttgga
     8761 atggatacct tgcgtgcctt agggtttgat gaagaagtga ttttggatat cgttcgcact
     8821 cacgatgctc caaccccatt cccatcaaat gaaaaagatc tgaataagat gaaagaatgg
     8881 ttagcaacgg ttatcaaact tgacttgggc agccgtaaag atcctttgca acgtaaagga
     8941 ctttcactgt tacccaactt agaaacttta ggaattggct ttacaccaat caaagatatc
     9001 tcacctgttt tgcaatttaa aaaattgaaa cagttgttaa tgacaaaaac aggggtgact
     9061 gattatagat ttttggataa tatgccacag ttagaaggca ttgatatttc acaaaacaat
     9121 ctcaaagata ttagtttctt gagcaaatat aaaaacttaa ccctagtagc ggctgctgat
     9181 aatggtattg aagatattag gccgcttggt caattaccag atctcaaatt cctcgtattg
     9241 agtaataata agatttctga tttaagccca ctggcatcgt tacatcaatt gcaagaattg
     9301 cacattgata ataatcagat tacagattta agccctgttt ctcataaaga atcattgacg
     9361 gttgttgatt tatcaagaaa tgctgatgtt gacttagcaa cacttcaagc acccaaatta
     9421 gaaacgttaa tggtcaatga taccaaggtt tctcatttgg atttcttgaa aaataatcct
     9481 aatctatcta ttaaccgtgc gcaattgcaa tctcttgaag gtattgaagc aagtagcgtc
     9541 attgtcagag tagaagcaga aggtaaccaa attaaatcgc ttgtgcttaa agacaagcaa
     9601 gggtcactta ctttcttgga tgtgacaggc aaccagttga cttctctaga aggtgttaat
     9661 aattttacag cacttgacat tttaagcgtg tctaaaaacc aattaacaaa tgtcaactta
     9721 tctaaaccca ataagacagt tactaacatt gatattagtc ataacaatat cccattggca
     9781 gaccttaaat tgaacgagca acatattcca gaagccattg cgaaaaactt cccagcggtt
     9841 tacgaaggtt ctatggtagg taatggaaca gctgaagaaa aagcagctat ggctactaag
     9901 gcgaaagaaa gtgctcaaga agcatcggaa tcacatgact acaaccataa tcatacctat
     9961 gaagatgaag aaggtcatgc tcacgaacac agagacaaag atgatcacga ccatgaacat
    10021 gaggatgaaa atgaagctaa agatgagcaa aaccatgctg actaaactaa tctaagaata
    10081 acccgatcca actgaatcgt cctaatgaca ccattgttga ctatcaagag aacctcaaga
    10141 ataaccttga ggtttttttg aaataaatag gataatgagt gaaaagaatg gcacctaaat
    10201 ggctaaaaca tgttataata gattgttatt gagtcccgat aagacggtct gttgaacgaa
    10261 atgtttttga gacgttgttg acttcatttg gggaacagtc gttctccctt tagctaaatt
    10321 acttcgtcta aggcttattt tgtggtgaca tcctctcaac aaggagaccg gattctttgt
    10381 aactcaacgc tattgtcaga cattctttgt ctggttaatg gacgctagcc actaggtgga
    10441 ctagctagtt gccttactag taaaaccgta actgattagc taagttggtt ttggccactt
    10501 gacttgctca atcagctagg aagaaagggg taggcaactt cttgctttgt ggtcaatgtg
    10561 actgaaaaag gaagaatcaa catattaggg ggggcatttt tatgtcagaa cgtaaacttt
    10621 tcacgtctga gtccgtatct gaagggcatc cagataagat tgcagaccaa atttcagatg
    10681 ctattttaga tgccatttta gcagaagatc cagaagccca tgtggctgca gaaacttgtg
    10741 tttacacagg ttctgttcat gtttttggag aaatctcaac aacagcatac attgatatta
    10801 accgtgtggt ccgcgacacc attgcagaaa ttggttatac agaagcagaa tatggctttt
    10861 cagcagaatc agtgggagta catccatcac ttgtagaaca atctggagat atcgctcagg
    10921 gggttaatga agctctcgaa agcagagaag gtgatactga tgaccttagc catattggag
    10981 cgggtgacca agggctcatg tttggttttg ccatcaatga aacaccagaa ttgatgcctt
    11041 taccaatttc cttatctcac caattagtgc gtcgcttggc ggaattacgt aagtcaggtg
    11101 agattagtta tctacgtcca gatgctaaat ctcaagtgac agttgagtac gatgaacacg
    11161 ataaacctgt tcgtgtggat acagtcgtta tttctactca gcatgatcca gaagctacta
    11221 atgaccaaat tcgtcaggat gtgattgaaa aagtgatcaa ggctgtaatt ccagcagatt
    11281 atttagatga tgacacaaag ttcttcatta atccaacagg acgttttgtt attggaggtc
    11341 cgcaaggaga ctctggattg accggacgta agattattgt ggatacctat ggaggctatt
    11401 cacgtcatgg tggcggtgct ttttcaggaa aagatgcgac aaaagtggac cgttcggctt
    11461 cttacgctgc tcgttatatt gctaaaaacc ttgtggcagc aggtcttgcg acgaaagctg
    11521 aagtccaact agcttatgcg attggggtgg ctcagcctgt gtctgttcgc gtggatacat
    11581 ttggaacctc aacggttcct gaagctgttt tagaagctgc tgttcgtcaa gtctttgatt
    11641 tacggccagc aggcattatt caaatgcttg atttaaaacg cccgatttac aaacaaacag
    11701 ctgcctatgg tcacatgggg agaacagata ttgatttgcc atgggagcgt ttaaataagg
    11761 ttgatgcttt agtagaagct gtaaaaacag tattataaac gacaacttta ttaaaaaagt
    11821 agagtaagtg aaaaaatctt actctgcttt tttgttatta aataagcctt taaaagggat
    11881 gattaaaaat taagacgtca ataattgtca ggcttcatga tttatgataa aatgaaaagg
    11941 ttgaattcta gtataagaaa gttttgaatg tatgcgtaaa attattatta atggcggaaa
    12001 agccttatct ggagaagtgg cagtttcagg ggcaaaaaac agtgttgttg cgcttattcc
    12061 agcaatcatc ttagccgatg atattgtgat tcttgatggt gtacctgcta ttagtgatgt
    12121 agatagtctg attgaaatca tggagcttat gggagcaaca gtaaactatc atggtgatac
    12181 tttagaaatt gaccctagag gggtgcaaga catcccgatg ccttacggaa agattaatag
    12241 tcttcgagct tcctattatt tctacggtag tcttttaggt cgttttggac aagcagttgt
    12301 tggcttacct ggtggttgcg atttaggacc aagaccaatt gacttgcatt tgaaggcctt
    12361 cgaggctatg ggagttgaag tgtcttatga gggtgaaaat atgaatttat cgacaaatgg
    12421 tcaaaaaatt catggcgctc atatctatat ggacaccgtt agtgtcggtg ctacaattaa
    12481 tactatggtt gcggcaacaa aagctcaagg taaaacggtt attgaaaacg ctgcacgtga
    12541 gccagagatt attgatgtgg ctactctttt gaataacatg ggtgcgcata ttcgtggagc
    12601 aggtacagat attattacga tacaaggtgt tcagaaattg catggtacta gacaccaagt
    12661 tattcctgat cgtattgaag cagggactta tatcgctttg gcggcagcta ttggaaaagg
    12721 tgttaagatc actaatgttc tttatgagca tttagagagt ttcattgcta agttagaaga
    12781 aatgggtgtc cgtatgacgg tagaagagga tgctatcttt gttgaaaagc aagaatccct
    12841 caaggctatt acaattaaaa cctctcctta ccctggtttt gccactgatt tgcaacagcc
    12901 attaacgccc ttgttgttaa aagcagatgg tcgtggaacg attattgaca ctatatatga
    12961 aaagcgcatt aaccatgtgc cagagttgat gcgcatggga gcagatatct cagttattgg
    13021 tggtcagatt gtttatcaag ggccgtctcg cctgacagga gctcaggtca aagccactga
    13081 tttacgtgcc ggagcggctc tagtgactgc tggtctaata gctgaaggca agacagaaat
    13141 tactaatatt gaatttatct tacgtggcta tgctagtatc attgcaaaat taacagcact
    13201 aggggcagat attcaattaa tcgaagacta aagagaagct aacgcttctc ttttttatat
    13261 tacatgtgct taggctaatg atacttaggt gcatactttg ttgcatttta tggcttttta
    13321 actgt
//
LOCUS       DAUNLR010000047        13172 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUNLR010000047 DAUNLR010000000
VERSION     DAUNLR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13172
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.047"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            537..1064
                     /locus_tag="VLL59_001383"
     CDS             537..1064
                     /locus_tag="VLL59_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HER6509502.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1064..2182
                     /gene="yqeH"
                     /locus_tag="VLL59_001384"
     CDS             1064..2182
                     /gene="yqeH"
                     /locus_tag="VLL59_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HER6509503.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2207..2515
                     /gene="yhbY"
                     /locus_tag="VLL59_001385"
     CDS             2207..2515
                     /gene="yhbY"
                     /locus_tag="VLL59_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HER6509504.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2584..3216
                     /locus_tag="VLL59_001386"
     CDS             2584..3216
                     /locus_tag="VLL59_001386"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HER6509505.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDTKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKFHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3213..3806
                     /gene="yqeK"
                     /locus_tag="VLL59_001387"
     CDS             3213..3806
                     /gene="yqeK"
                     /locus_tag="VLL59_001387"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HER6509506.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECH
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3830..4183
                     /gene="rsfS"
                     /locus_tag="VLL59_001388"
     CDS             3830..4183
                     /gene="rsfS"
                     /locus_tag="VLL59_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HER6509507.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            4231..4974
                     /locus_tag="VLL59_001389"
     CDS             4231..4974
                     /locus_tag="VLL59_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HER6509508.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRYLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            5228..6334
                     /locus_tag="VLL59_001390"
     CDS             5228..6334
                     /locus_tag="VLL59_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HER6509509.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDVID
                     YQKLIKVYEKKSEQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISRSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6816..7532
                     /locus_tag="VLL59_001391"
     CDS             6816..7532
                     /locus_tag="VLL59_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HER6509510.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTVANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7735..8577
                     /locus_tag="VLL59_001392"
     CDS             7735..8577
                     /locus_tag="VLL59_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HER6509511.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMAG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8904..9749
                     /locus_tag="VLL59_001393"
     CDS             8904..9749
                     /locus_tag="VLL59_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HER6509512.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9999..11063
                     /locus_tag="VLL59_001394"
     CDS             9999..11063
                     /locus_tag="VLL59_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HER6509513.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKVQLSANALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11064..11756
                     /locus_tag="VLL59_001395"
     CDS             11064..11756
                     /locus_tag="VLL59_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509514.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGAAFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11810..13144)
                     /gene="brnQ"
                     /locus_tag="VLL59_001396"
     CDS             complement(11810..13144)
                     /gene="brnQ"
                     /locus_tag="VLL59_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HER6509515.1"
                     /translation="MLFALFFGAANLIYPAFLGIYSGHQILWSIIGFCLTGVSLPLLG
                     VIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGATSFSVGIAPILG
                     DNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISILVIASFVHPAGNY
                     GDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEATKQFGAKTDKEVT
                     KITLISGAIAILLLALVYIFVGRIGATSQSLFPFSDGSFTLHGNPVNGGQILSHASRF
                     YLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWATIFTLLSAFFYF
                     GGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIGLTFIPAIFDALL
                     TLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLILSKTKKS"
BASE COUNT         4329 a         2077 c         2755 g         4011 t
ORIGIN      
        1 ggtaaatcta tgaaaaaagt gtaatcattt tttgatttac agttattatc atgtgttatc
       61 tggcgactgt cctgtttaca agtaagttca caagtatggg ataaaatagt ataaactata
      121 gtaaatactg aatagtcaaa gaaaaatatc ggcataggtc agaagagctg atatgtttaa
      181 tactttttgc ggatatctac tgtatttaaa tgtatttgat atccttgtca aggatatacg
      241 tctaaacaag ttcaaaacga aatcatttgt gattatctta tcaggagttg actcttgata
      301 agatttttgt atatcagtac tgtggtacgt ttagatagct tggcagtgaa tttatagagt
      361 gtcaaacaac gagtgttttg tgttacacta accattagaa gagtctattg ttgagcatat
      421 caaggtgtta tcttttcgag ttgaggtatc atatctagta tatttaacta tggttttaaa
      481 tgctatttca aaaaaaatat gataaaatag aaagtactaa ttattttgga gatgacatga
      541 gtatcgatga ttataggccg acctatatgg tagaggctat ttatgattta agagcaaatg
      601 atttgttgcg tcatggtatt acggctgttt tagtggattt agataatacc ttaattgcat
      661 ggaataatcc tgatggcaca ccagaggttc gcgcttggct tgatgaaatg actatcgcgg
      721 atattagcgt ggttgttgtt tcaaataata aacattctcg tgttgagcgt gccgtttcac
      781 gctttggtgt tgactttatt agccgggctt tgaagccatt tgcttatggt attgaaaaag
      841 ccattgctcg ttatggattt gatcgcaacg aggttatcat ggttggagat cagctaatga
      901 ctgatatcag agctagtcat agagctggaa taaaatcagt tttagtcaaa ccacttgttg
      961 cttctgatgc ttggaatact aaaattaacc gctggcgtga acgccgtgtg atggcaaaat
     1021 tagaagagaa atatggtaaa ttatcatatc aaaaaggaat ttaatggaag aattattttg
     1081 tataggctgt ggtatccaga ttcaaactga agataaagaa aaagctggtt ttacgccagc
     1141 tgctgctttg aaaaagggta tggaaacagg agaactctat tgtcagcgct gctttagatt
     1201 gaggcattat aatgaaatta cagatgtcca tattaccgat gatgaatttt taagacttct
     1261 tcacgaagtg ggtgatagtg atgctcttgt ggttaatgtg attgatattt ttgactttaa
     1321 tggttctatt attccaggtc tatctcgctt tatttctggt aatgatgtct tactggttgg
     1381 gaataaaaaa gatattttgc caaagtctgt taaggatggt aaagttactc aatggttgac
     1441 ggaacgtgca cacgaagaag gtcttcgccc tttagacgtt atgttaacaa gcgctcaaaa
     1501 taaatatgcg atcaaagact tgattgagcg tatcaatgag ttacgtaatg gtcgagatgt
     1561 ttatgttgtg ggggtcacta atgttggtaa atcaaccttg attaatgcga ttatccaaga
     1621 gattactggt aacaaggatg tcatcacgac gtctcgtttt cctgggacaa ctcttgacaa
     1681 aattgaaatt cctttggatg atgggacgtt catttttgat acaccaggaa ttattcatag
     1741 gcaccagatg gctcattatt tatcccctaa agagctaaaa atagtgagtc ctaagaagga
     1801 aatcaagcct aagacgtatc aattaaaccc agaacaaact ctctttttag gtggtttgtc
     1861 tcgctttgac tttatcaatg gggagcgtca agggtttaca gctttttttg acaatcaact
     1921 agaattacat cgtacaaaat tagctggagc agatgctttt tatgataagc atgttggaac
     1981 tttgttaact cccccaggta agaaagagtt gacagcattt cctaaattag ttcgtcatga
     2041 atttacaatt gatcagaaaa tggatattgt tttttctggt ctaggatgga ttcgtgttaa
     2101 tggtcaaaaa gactcaaaag cgatagttgc tgcatgggct cctgaagggg tcgctgtcat
     2161 tgttcgtaaa gcgattattt aaaaataaaa aagaagttgg aaaaaaatgc ttacaagtaa
     2221 acaaagagct ttcttaaaat ctgaggctca tagcttaaaa ccgattgtac aaattggcaa
     2281 aaatggatta aatgaccaca ttaagactag tattcgtcaa gctttggatg ctagagaatt
     2341 gataaaggtc actttgttgc aaaatactga tgaagatatt catgaagtag cagagatttt
     2401 agaagaagaa attgggtgtg atacggtttt gaaaattggt cgtatcttga ttctctataa
     2461 ggtttctgct aagaaagaaa accgcaagtt gtcccctaaa gttaaagcaa tctagtcctt
     2521 ttatttgtat aggggctggt cttatgagac gaggactatt gtcgcgagaa ttttggagaa
     2581 agtatggcat tagaattgtt gacgcctttt acgaaggtgg aattagagga agaaaaaaaa
     2641 gaaagcaacc gcaaacagat tgggatttta ggagggaatt ttaatcctat tcacaatgca
     2701 caccttgtgg ttgcagatca agttcgccag caattaggat tagatcaggt gctattgatg
     2761 cctgaatgta aaccaccgca tgtggatacc aaagagacta ttgatgagaa acatcgtctt
     2821 cgcatgttgg aattggctat tgaagatgtt gaagggctag ctattgaaac ctgtgaactt
     2881 gaacgtcagg gaatcagcta tacctatgat acgatgcttt atttgactga gcagcatcct
     2941 gatgtcgatt attattttat catcggagct gatatggttg attatttgcc aaagtttcac
     3001 cgtattgatg aactggtcaa actcgttcaa tttgttgggg ttcaacgtcc aaaatataaa
     3061 gctggaacct cttacccagt catttgggta gatcttcctt tgatggatat ttcttctagt
     3121 atgattaggg attttattaa aaaaggtcgt cagcccaatt atctcttacc taagcgggtt
     3181 ttagactaca ttactcaaga aggtttgtat caatgacata tgaagattat cttccttata
     3241 gcaggaccga actgttagca aaaattgcag agcagatgag ccctaaacgg tttaaacatg
     3301 tacttggcgt ggaaaaggca gccttgtcct tggcagagtg tcatggttgt aacccagaca
     3361 aagcagggtt agcagctctt ttacatgatt atgccaagga gtgccctgac caggtctttt
     3421 tagacttaat tgacaagtac caattatctc cagaattagc taaatggaat aataatgtct
     3481 ggcatggtat ggttggtatt tataagattc aagaagacct aggcctaaaa gacaaagata
     3541 tcttgcgagc tattgaaatt cacaccgttg gtgctgctga gatgaccttg ctggataagg
     3601 tcttatacgt tgctgattat attgaagaag gtcgcatttt tcctttggtt gatgacgcta
     3661 gaaaaatcgc gaagctcgat ttgaatcagg ctgttgccta tgaaacagtg aacactgtcg
     3721 cttatttagc ctcaaaagcg cagcctattt tcccacaaac tctggatacc tataatgcgt
     3781 tttgcagcta tttaaaggaa tactaatgga taatgatatg aggaataaaa tgaaaaaaga
     3841 agaactctta aaaattgttg tggaagcaac tgatgaaaag cgtgctaaag atattttagc
     3901 cttggattta gaggggttaa ctagtttgac tgattatttt gtgattgcga gtgcaacaaa
     3961 tagtcgtcaa ttagaggcta ttgcggataa tattcgtgaa aaggtaaaag aggctggtgg
     4021 agatgctagc catgttgaag gtaatagcca agcaggctgg gtcttgcttg atttgaccga
     4081 tgtggtggta catctttttt tagaagacga gcgttaccac tataatcttg aaaaattgtg
     4141 gcatgaagcg cctgctgtgg ctctagatgc ctatttagct taatgttaca aagagacctt
     4201 gtcaatacga cagggttttt gaggatgata atggaacata attatgaaaa atttgcgtca
     4261 gtttatgatg ctgtgatgga tgattctcta tatgacttgt ggacagattt ttcacttcga
     4321 tatttaccaa agtctaaggg tcgaaatcgt ttgttagagt tggcctgtgg aaccggtatt
     4381 cagtcagttc gttttgctca agcaggtttt gatgtgactg gtttagactt aagtcaagac
     4441 atgctggcta ttgctaaaaa gcgtgcgcaa tctgctaaaa agaaaattga ttttattcaa
     4501 ggtaacatgc tggatttgtc acaggtgggg cagtttgatt ttgtaacctg ctattcggat
     4561 tccatttgct atatgcaaga cgaagttgat gttggcgatg tttttaaaga agtttatgat
     4621 gttttagcaa acgatggcat ctttattttt gatgtgcatt caacctatca aacggatgag
     4681 tgtttccctg gttattccta tcatgagaat gcagatgatt ttgcaatggt ttgggatacc
     4741 tatgctgacg aggctcctca ctctgttgtt cacgaactca ctttctttat ccaagaagac
     4801 gatggacgtt tttctcgctt tgatgaagtg catgaggaac gaacgtatga gttattgact
     4861 tatgatattt tgttggaaca agcagggttc aagtcattta aggtctatgc tgattttgaa
     4921 gataaggagc caactaagac cagcaagcgt tggttttttg tagcatataa atagaagaaa
     4981 aaagtagcct ttttagctat aggatttaat gaattatctt gaatgttact tatatgaaaa
     5041 gagttcatta ggcattaaat gctattatca aagcttagaa gtattggaga cattacgatt
     5101 gacactatgt ctgaaggttg ctaccaactt taaagaaagc attttctatt atacgttgtg
     5161 cttaagcatt tgatttaact cttattagcc ctataaaaga ctatttagta caatttgagg
     5221 agattctatg actgttaccg gaattatagc tgagtttaat ccgtttcaca atggacacaa
     5281 atatttgcta gaaacagcag agggactaaa aattattgct atgtcaggaa attttatgca
     5341 aagaggagag cctgctctta ttgataaatg gattcgatca gagatggctc ttaaaaatgg
     5401 tgcggatatt gttgtggaat tgcccttttt cgtttcagtt caatcagcag actattttgc
     5461 tcaaggagct attgatattc tttgtcaatt aggaattcag caattagcat ttgggacaga
     5521 ggatgtgatt gattatcaaa aactgattaa ggtctatgag aaaaaatcag agcaaatgac
     5581 tgcctattta tcgacgcttg aagatacact tagctatcca caaaaaacac aaaaaatgtg
     5641 ggaaatcttt gctggagtta aattttcagg gcaaacgcca aatcatattt tggggttaag
     5701 ttacgcaaag gctagcgctg gaaagcatat acaactatgt cctatcaagc gtcaaggggc
     5761 tgcctaccat tcgaaagaca aaaatcatct gctagcttct gcaagtgcca ttagacagca
     5821 cctgaatgat tgggatttca taagtcgttc agtaccaaat gcaggtttac ttataaacaa
     5881 tccccatatg tcatgggacc attatttttc attcttaaaa tatcaaattc tgaaccattc
     5941 tgatttaact agtatttttc aggtcaatga tgaattggca agtcgtatta aaaaagcgat
     6001 aaaagttagt caaaatattg accacctagt tgacactgtt gctaccaaac gctatacaaa
     6061 agctcgtgta agacgtattt taacctacat tttggttaat gctaaggaac ctactttacc
     6121 taaaggaatt catattctag ggtttacctc aaaaggacaa gcacatttaa aaaaattaaa
     6181 aaaaagcagg cctctgatta ctagaattgg agcagaaact tgggatgaga tgacacaaaa
     6241 agcagacagc atctatcaac ttgggcatca ggatatccca gaacaaagtt ttggaagaat
     6301 acctattata ataaaaaatg agaggctcaa ttaaactcta attgagtttt tttgggggct
     6361 tgactctaac attacgttga tggtttatac ttcagttaat ccaatgagga aattttataa
     6421 caataattaa aaaagtcagt caaaagatat gctttcgaag aacaggctaa cgtttttaca
     6481 agattatatc agtaatcatt ttgacaattg tagtaatgga atgttaccaa aatttagaac
     6541 gttgtgtgtt atggatgaca agattttaaa ggaatactaa ttaaacggga ggtcgtgaac
     6601 cggaagctgt tgtcactcaa gcgccaaaat ctgtctgtaa cataatattg atgtatggga
     6661 acgcaattat ttggttttta ttgtgatgct taaaacgatt ttatatttct attttaccaa
     6721 agcttttcaa agtgctataa taagggagtt agagtcaata ttagtaacgt taatgttgac
     6781 aatattcaat aaaatactat taaaaggaga caaaaatggg acgtaaatgg gcaaatattg
     6841 ttgctaaaaa aactgctaaa gatggagcaa catcaaaggt ctatgccaaa tttggtgttg
     6901 aaatttatgt ggctgccaaa caaggcgagc cagatccaga gttaaataca gctcttaaat
     6961 ttgtcattga tcgtgcaaag caagcacaag tgccaaagca tgttattgat aaagcgattg
     7021 ataaagctaa aggaaacaca gatgaaactt tcgtagaggg acgctatgaa ggttttggtc
     7081 caaatggttc aatgattatt gtggatactt tgacatcaaa tgttaaccgt acagtggcaa
     7141 atgtacgtac ggcttacggt aagaacggtg gcaatatggg agcttcagga tctgtatcct
     7201 acttatttga taaaaaaggg gtcatcgttt ttgctggtga tgatgctgac agtgtctttg
     7261 agcaattact tgaagcggat gtagacgtag atgatgttga agcagaagag ggaacaataa
     7321 cagtttatac cgccccaaca gatcttcata aaggtatcca agcacttcgc gataatggtg
     7381 tagaagaatt ccaagttact gaacttgaaa tgattcctca atcagaagta gtattggaag
     7441 gtgatgacct tgaaactttt gaaaagctta ttgacgcact cgaatcagat gatgatgttc
     7501 aaaaagtgta tcataatgta gcagattttt aaattgacat agaataataa aaagagttga
     7561 aatttatttc agctcttttt aagtgatgct tttataagta agtaccaggt aacatagtcg
     7621 ttgttagaag ataatgaaca atagtaaatc agtatcaact tgataggaat caattattag
     7681 tgaactctaa ttaaaaatgg taaactagac acaagaacaa aaaggagaga taggatgatt
     7741 aaaaaacaat atttaggaag ggcaacaatt gccctagcat caacccttgt gctagcagct
     7801 tgtgggtcat caaaaacagc tgagtcagga aatcagggga gttctaaaga agtcttattt
     7861 gcaacggttg gaacaacagc tcccttttct tatgaaaaag gtggtcaact aactgggtac
     7921 gatatcgagg tggctaaagc agtctttaaa ggatcggatg attacaaggt gtcctttaaa
     7981 aaaacagaat ggtcttctat ctttacaggt ttggactcag gaaaatacca aatggctggt
     8041 aacaacattt cctttaccaa agagcgttca gctaagtacc ttttttctta tccaatcgga
     8101 tcaacacctt ctgttttagt tgttccaaaa gacagtgata tcaagagctt tgatgatatc
     8161 caagggcata cgacacaagt tgttcaaggg actacaagtg ttgcacagtt agaagacttt
     8221 aataagaaac acagtgacaa cccggttact ctaaaattca ccaatgagaa cattacccaa
     8281 atgttaacca atttgagtga aggcaaggca gatttcaaga tttttgacgc tccaacggtt
     8341 aacgccatta ttaaaaatca agggttagat aatctcaaaa caattgaact cacctcaaca
     8401 gagcaaccat ttatttattt tatctttagt caagatcaag agaaattgca aagctttgtt
     8461 aacaagcgta ttaaagagtt gactgctgac ggaactctta gcaagcttgc caaagagcac
     8521 cttggcggtg attacgtgcc atcagataaa gagttaaaac ttcctacagc taactaaacc
     8581 atctattaac cagttattca tctagaagac tggtttttct gatcggaaat aatattatag
     8641 tttatgaggt tatgttataa aaattgcaaa tagccttaat caaaatgaga tgttaaagtg
     8701 ctttttgaga agtgaatatt gtaagaagta tgctttgggt tttagtcctc aaataccaag
     8761 ttttttgttg actaaacaaa taaggatggt tagcatagca tatagtttaa aactatgcta
     8821 tatgctagcc attatcaatt tgaaaactat atctaattaa gatacaataa tgatcgtaaa
     8881 caaaatgaat cgaggataac gctatgtctt ttaaaaaatg gattggaata gtcggaatcg
     8941 ctttagcatc aactgtatta gttgcttgtt ctgaaaaaca agatgataaa aacactttaa
     9001 ctattggggt gatgacaaaa acagaatctg atcaagcgag atgggataaa gttgaagaat
     9061 tattgaaaaa agacaatatc actttgaagt acaaagaatt tacagattac tcgcaaccta
     9121 ataaggcagt tgctaatggt gaagtcgata ttaatgcctt ccaacactat aatttcttaa
     9181 ataactggaa taaggaaaat aaggaacatt tggtggccat tgctgatacc tatatcagcc
     9241 caattaacct tttctctgga accagtcaag atgggaaggc taaatacaaa tcagtagctg
     9301 atctgccaaa tggtgctcaa attgcagtac caaatgatgc gaccaatgaa agccgtgccc
     9361 tctatgtgct gcaatcagct ggcctcatta aattgaatgt gtctggtgat caattagcaa
     9421 ccattgccaa tatctcagag aacaaaaaga aattagatat caaggaatta gatgctagcc
     9481 aaacggcacg tgctttagta tctgctgatg cagctgttgt caataatagt tacgctgttc
     9541 ctgcaaaaat tgactacaaa acctctcttt tcaaagaaaa agcagatgac aattcaaaac
     9601 agtggattaa cattattgca ggtcaaaaag attgggaaaa atcagagaag gctgatgcta
     9661 ttaaaaaact catcaaggcc taccaaactg atgaggtgaa gaaagtcgtg gaaaaaactt
     9721 caaatggtat agatgtatcc gtatggtaaa ttttagccat tgttataaca agagtgtggt
     9781 tgtgtttaaa acacatgctt tcttgcatgc ttgaggaaga gtttacgatt aatttacctt
     9841 taggaagcta tttaagacct tttccctttt aggatttagc aaccttggga agactattgc
     9901 atgttatctt aatagtcatg attatgcagg cgatgaaaac attgctatcg tagattactg
     9961 tcgccatatc gtactaatag aggagttatt aaaatcttat gaatgaagca ataattcaat
    10021 tagatcatat tgatattacc ttccgtcaaa aaaaacgggt tatcgaagct gttaaagatg
    10081 tcacggttca tatcaatcaa ggagatattt atggcattgt tgggtattca ggtgccggga
    10141 aatcaactct tgtgcgtgtg attaacctgc tacaggcacc aacaaacggg aaaatcactg
    10201 ttgatgggga tgtgaccttt gaccagggga aagttcagtt atcagccaat gcccttcgcc
    10261 aaaaacgacg tgatattggt atgatcttcc aacatttcaa tttgatggcc caaaaaacag
    10321 ccaaagaaaa tgtagcattt gcgctccgtc attcgtcgtt aagtaagact gagaaagaac
    10381 acaaagttat cgaactgcta gaacttgtag gtttatcaga gcgagcagat aactaccctg
    10441 cccagttatc gggtgggcaa aaacaaaggg tggctattgc gcgtgctcta gctaacgatc
    10501 ccaaaatttt gatttcagat gaggccacat cagcactaga tccaaaaacc actaaacaaa
    10561 ttttggcact cttgcaagaa ttaaaccgca aacttggcct taccattgtt atgattactc
    10621 atgaaatgca aattgttaag gatatttgta atcgtgttgc tgttatgcaa aatggtgttt
    10681 tgattgaaga aggttctgtc cttgatatct tttcaaatcc aaaagaagcc ttgacacagg
    10741 aatttatcac aacagctaca gggattgatg aggctttaga aaaaattaac caacaagaca
    10801 ttgttaaaca tttgcctgca aatgcccttc tagctcagtt gaaatatgca ggaacttcta
    10861 cggatgagcc tctacttaat agcatttacc gtcagtttga agtgacagct aatattttgt
    10921 atggcaatat tgagatttta gatcatattc cagttggtga catgattgtt gtcttggaag
    10981 ggcaagctga aaatattctt gcggctgaga aagccttgca tgaagctggt gttgatgtta
    11041 gtattttaaa gagaggagcc tagatgtcac agttaattca aacttatttg ccaaatgttt
    11101 atgaactcgg atggtctgga gatgctggtt ggggcttagc gatttggaat actttataca
    11161 tgaccattgt gccttttatt gttgggggtg ctattggtct cttattaggc ttgttattag
    11221 ttttaacagg accggacggt gttattgaaa acaaaacgat ttgttgggtt attgataaag
    11281 ttacctctat ttttagagcc attccttttg ttattttgat tgctatttta gctagcttta
    11341 cctatttgct tttaagaaca actttaggag caacagcggc cttggtacct ttaacctttg
    11401 cgacttttcc tttttatgcc cgtcaggtcc aagttgtttt ttcagaatta gacaagggtg
    11461 ttattgaagc agcacaagct tcaggtgctg ctttctggga tattgtcaaa gtgtatctca
    11521 gtgaaggttt accagatctt attcgtgttt ctacagtcac cttaatttct ttagttgggg
    11581 aaactgccat ggcaggagct atcggtgctg gaggattagg aaatgtagcg atttcttatg
    11641 gttataatcg ttttaacaat gatgtgactt gggtagcgac tattattatt cttttaatta
    11701 tttttgctat ccaatttatt ggtgatagct tgactagaag gtttagtcat aaataaacga
    11761 aacaacaccc taagtaaaaa cttagggtgt tgttgtttag atgatgtcat tagcttttct
    11821 tcgttttact tagtataagc cctattaaaa aaccaatagc agcaaatata atccatccca
    11881 ttgagaattg ccctagtgga acagtttttt ggaaaaaagt tacaacggct tctggtaaat
    11941 gaaataatcc agtcatttgt gatagtgtta ggagtgcatc aaatatggca ggaataaagg
    12001 ttagaccaat tgtagttcga tagacgatag gatcattatt gaagcatttt tgtgccaaaa
    12061 caaggaaaat taaatcgact gttaatgggt ataaaaggaa taaaacagga gctgaccagt
    12121 tgataatgac tgataagcca ccaaaataaa agaaagctga tagtaaagta aagatagttg
    12181 cccaagcaat atgagataaa gcaggcacta atttatggaa gtattcagca cttgacgtga
    12241 ttaagcctgt tgaagtggtt agacaggcca ggaaaatcac aacagctaga aatgcttgtc
    12301 cgatgccacc taggtaaaaa cgagaagcat gacttaagat ttgaccgcca ttaactggat
    12361 taccatgaag ggtaaagctg ccatcactaa aaggaaataa tgattgtgat gttgctccaa
    12421 tacgaccgac aaagatatag acaagtgcta atagcaaaat ggcaatagcc ccagaaataa
    12481 gtgttatttt ggtcacttct ttgtccgtct tagcgccaaa ttgtttggta gcctcaatga
    12541 ctaaaatagc aaaaacaaga gaagctagtg catccatagt gccataacct tgaattaatc
    12601 ctgctataaa aggaaaatct ttaaaggcat tattaacacc gaccccagcg ttaaaagcat
    12661 caccgtaatt tccagcagga tggacaaagg acgcgataac caaaatagaa ataacaacta
    12721 acaacgttgg cgttaaaaat tttccgatat tttcagctag cttactaggt ttgatagcaa
    12781 ggaagtagga cagaccaaaa aatagtatag cataaatagc tttattggtt gtattatctc
    12841 ctaagatagg agcgataccg actgaaaaag aagtggctcc tgttcttgga atagcaaaaa
    12901 atgggccaat agataaatac aaaatggaag aatagaagat tgcataccat ttagagatgg
    12961 ggcgtgccaa actttcaaca tcgcctgatc cagatttagc aacagcaatg acaccgagta
    13021 aaggcaagga gacaccagtt aaacaaaaac caatgataga ccatagaatc tgatgacctg
    13081 agtagatgcc taaaaaagct gggtaaatga ggtttgctgc tccaaaaaat agcgcaaata
    13141 gcatgaatcc aatgacgata tatacatttt tt
//
LOCUS       DAUNLR010000048        13094 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUNLR010000048 DAUNLR010000000
VERSION     DAUNLR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13094
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.048"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            85..324
                     /locus_tag="VLL59_001397"
     CDS             85..324
                     /locus_tag="VLL59_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509516.1"
                     /translation="MTKMTLRALRVNYSLSAKEVAQELGIHQQTLLKYEIDSTDIPFS
                     LLNELANYYNIDVNNIFLGKKFVLKQMFKNNRLQN"
     gene            complement(416..625)
                     /locus_tag="VLL59_001398"
     CDS             complement(416..625)
                     /locus_tag="VLL59_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509517.1"
                     /translation="MGPNYFHVQFKLGEKVSYNTPSAEGREVIPIKGAEVTKMIFADG
                     NELLSVIHNETVDVYASFPIVLEYH"
     gene            705..953
                     /locus_tag="VLL59_001399"
     CDS             705..953
                     /locus_tag="VLL59_001399"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509518.1"
                     /translation="MNSLKLSIKPKLEPNDGQCLLSSGYSVKINDWELGKGVVDFRLE
                     MPADKKPKATITFIPNLVDIDGMMAAGVQGLLPESDID"
     gene            complement(927..1142)
                     /locus_tag="VLL59_001400"
     CDS             complement(927..1142)
                     /locus_tag="VLL59_001400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509519.1"
                     /translation="MAFSKEIADKILEFAALEPTIPVGVGHDFQTDAFDQDDVLDTAK
                     HLISTGQIKAKIENHYYNGLVNIAFRQ"
     gene            1248..1559
                     /locus_tag="VLL59_001401"
     CDS             1248..1559
                     /locus_tag="VLL59_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HER6509520.1"
                     /translation="MPKAEITYRAVDVNETASHGDYKHLIQQWEGLTVATAKQWATEM
                     RDHPDFKQFVLNPTHRIVFIDYEGFKLFVQWKSRNRYKTKKESLPEMLENIKFEKRVG
                     V"
     gene            1711..2037
                     /locus_tag="VLL59_001402"
     CDS             1711..2037
                     /locus_tag="VLL59_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509521.1"
                     /translation="MNRIKELRKEKKVSQKEIADFLGISEKTISRWENSENTIKSDKA
                     KELAKYFNVSVAYLLGYSDTTKDNKDFITISVKEYNELKKQSDVLDGVIETLKDKRST
                     SYKIKS"
     gene            2107..2589
                     /locus_tag="VLL59_001403"
     CDS             2107..2589
                     /locus_tag="VLL59_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HER6509522.1"
                     /translation="MAYLYELEGIYAQLQSMDLDEETFQDTLDSIDFQADLENNIEYF
                     VKMLKNAQADEEMYKAEKEAFYEKQKQAQAKIDKYKETIHLAMALSNKKKVDAGMFKV
                     SLRKNKKVEVLDETKIPLEYMTEKIERKPDKKELAKLLKIGQEIAGVELIETESLQVK
                     "
     gene            2590..3270
                     /locus_tag="VLL59_001404"
     CDS             2590..3270
                     /locus_tag="VLL59_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HER6509523.1"
                     /translation="MKITKATEIKNNDSCYLIYGNPGFGKTSTAKYLPGKTIVINIDK
                     SAKVLRGNENIDIADIDTHKIWGEWLDTVKELLNGAANDYDNIVIDNVSELFRACLAN
                     LGREGKNHRVPSQADYQRVDFTILDSLRALLQLNKRIVFLAWETSDQWTDENGMIYNR
                     AMPDIRTKILNNFLGLTDVVARLVKKTTDDGEEVRGFILQPSASVYAKNRLDDRKGCK
                     VEELFETT"
     gene            3372..4601
                     /locus_tag="VLL59_001405"
     CDS             3372..4601
                     /locus_tag="VLL59_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6509524.1"
                     /translation="MAHIARSATDKGNRVLFFSHRKEINEQVERTFAANGVNSNLLTI
                     GGVQSLVRKLDSLSQPEVILIDEAHHSKAKSYLKIIDHFKNAYVLMFTGTPVRLNGDG
                     FDDIADDLVAGKSVKWLQEHGNIANFKYYAPSMIDNSALKKRGGEFTKDSVNQSMKSV
                     IYGDVIKHYEKLAKGKQAIVYTHSVEASHLVSDMFNQAGYQSQSVSGKTPKSEREEAM
                     QAFRDGKLRILVNCELFTEGIDLPNVDVCIMLRPTQSLSLYLQFAMRPLNPRDGKIAI
                     IIDHVGNVERFGLPNMDREWRLDGKTKQKQSTKIGEPTTRVCDDCYATYWSDTRICPE
                     CGHENELTKREIEEIKEAELQEISEQKQLKLKNRVSIYQSPDLCRTMDELTEYRKQHG
                     YKPGWQYHIAKKLGILY"
     gene            4617..5075
                     /locus_tag="VLL59_001406"
     CDS             4617..5075
                     /locus_tag="VLL59_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HER6509525.1"
                     /translation="MFEIDYSQAKEFASITDGTYETFVEKAVQDATKNGADFINIHFR
                     IRKDFQQEFQNNIIFHRIFAKKEDGKYPIGAIMNLAKQAGIPDGTKFKSLDDYLNQLL
                     NKCLKITVKNETSEYNGNTYNNLNVKRIEKSDIPTMVNPVEEFKEDDLPF"
     gene            5078..5890
                     /locus_tag="VLL59_001407"
     CDS             5078..5890
                     /locus_tag="VLL59_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HER6509526.1"
                     /translation="MRGMIDYAIYYQQKGFSVIPISKDGKKPLVAFADKPAFTEHELR
                     LIWKDNPDANIALKTDTFFVIDIDVHNDVDGLKNLREWEHARLIPKTLQATTPSGGRH
                     IYLKKPKGVSMAQNIGFIDGVDLKAHVNNYVLVPPSNNAKGMYEWDMVHSPTSGEMTE
                     APLELINVLRELKPAYEYDASSFTSGDYQGSNKTAKLFETIVLGFGDTGGRNNALAEF
                     VGGLLLRNVDVEIAYTLAKMANHKTADPLSDKEFERTFKSMCDKELRRRSGF"
     gene            5880..7361
                     /locus_tag="VLL59_001408"
     CDS             5880..7361
                     /locus_tag="VLL59_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HER6509527.1"
                     /translation="MDFEFYREKLNEEPGIEPGKPKTWSAIKSKLVAYRREWLEEAGK
                     DVKNLSELAVAIGINKFLHVITLENGKVAIYDPDQGYYIKDYKFAYKLIHILQPTFNE
                     TKCRNVLFMLASMDRKYGAMDFEPEYQDVRRYVLVKNGIYDKKNKALLPFDHRFINFS
                     TIETELIPNAPLPTIDGWDVESWLLDLMSGDKDLVQLLWQVVAASLNGNYSYRKSIWF
                     VGDGNDGKGTFQQMISNLVGFKNVAPLKLNQFSERFGLAIIEGKTVIIGDDVQAGIYV
                     DESSNFNSVVTGEPVSIEKKGENPYMAIFKKTVIQSTNGMPVFKNKSNGTYRRIIIIP
                     FKKTFSSAEDNWAIKDDYINRREVLEYVLWKSINLDFDKFYEPKVTQDRMREFKEENN
                     TILKFLNEYLEDVESTRLPVRFLWDVYQSWCTENGVTKPKKSNFEKELAINLPDGWEK
                     TKSKPLNYFKPINDKPYYWIDYNFQWDDSKDGKKTAVIVQKSY"
     gene            7606..7926
                     /locus_tag="VLL59_001409"
     CDS             7606..7926
                     /locus_tag="VLL59_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HER6509528.1"
                     /translation="MTTESLIQNQIRVALSKAGHMVFRANVGKVKTVDGRLFDTGLPK
                     GFCDLFGFKPDGQIFFIEVKNETGRVRPEQKNFMEVMASRGALVGVARSVEDALKIVN
                     DTSR"
     gene            7910..8266
                     /locus_tag="VLL59_001410"
     CDS             7910..8266
                     /locus_tag="VLL59_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509529.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADEEEADRVYRSVKYYKKL
                     NRLPPPDVLEWFQRIYTTEKMVALIKQSYRLKQKKTDEDDKIYEKWMFKNYGDVKLVK
                     KIKRMDALERARRMGL"
     gene            8508..8792
                     /locus_tag="VLL59_001411"
     CDS             8508..8792
                     /locus_tag="VLL59_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509530.1"
                     /translation="MTTDEALQNLRDDLNKIINVLKNDWKALLFLTIAIFGMMVTVSY
                     FSYRDARQYYEPQIYGLRTQLSRTQKQLKRASEDRTRQTKRIAEMTRNGG"
     gene            8795..9130
                     /locus_tag="VLL59_001412"
     CDS             8795..9130
                     /locus_tag="VLL59_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509531.1"
                     /translation="MDYLMIGIIVLSVVIFIMGFFILYYQAIIVNSMKNDFRRMRKEL
                     REELGFDSYNWSDSFRNMRRDIKSNKELISEINSLQIIKKAKEAKRLEELEQTKANVE
                     KEINKLNGG"
     gene            9133..9618
                     /locus_tag="VLL59_001413"
     CDS             9133..9618
                     /locus_tag="VLL59_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HER6509532.1"
                     /translation="MTDIKILDACCGSRLFWFDKNEPHTTFMDVRQEKFEMHGKKINV
                     NPDVIGDFRDMPFESNSFNLVVFDPPHLKYVGQNSIMKAQYGQLDKENWKEDISKGFE
                     ECMRVLKVGGTLVFKWSDCQVNVREVLSAIPFKPLFGQQRGTTHWMTFVKFAELTGNG
                     R"
     gene            9622..9849
                     /locus_tag="VLL59_001414"
     CDS             9622..9849
                     /locus_tag="VLL59_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509533.1"
                     /translation="MNKQNFEKLDKVKELLDELKIPEFMAPLLVGNQIMEIINDLHNE
                     PDQFGAQVLLPSPDKKYKFAVRICREENLED"
     gene            9947..10348
                     /locus_tag="VLL59_001415"
     CDS             9947..10348
                     /locus_tag="VLL59_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509534.1"
                     /translation="MKNENFLGYDLAELLEEKLVGKRLKSIDDEKIVLADGTVIKIEL
                     NEGCGGCGNGWSELNITTENPNLESAVMGVEYTEKYSEWDDEFKIFVYMTDNSVIEIY
                     GYDGVGNGYYGYGFWVTVKNPGDLIESELED"
     gene            10348..10983
                     /locus_tag="VLL59_001416"
     CDS             10348..10983
                     /locus_tag="VLL59_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HER6509535.1"
                     /translation="MLTTNQIHKLLGVKEVYKAPDTLIKIILDKEKREDLFRQFLKYE
                     TDVSYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQA
                     WQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGMVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEREFNVKEWIGDGIEHIENPLIEWI"
     gene            11256..11696
                     /locus_tag="VLL59_001417"
     CDS             11256..11696
                     /locus_tag="VLL59_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HER6509536.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALLSFSELYKEGMLLVEKLEKSWN"
     gene            12468..>13094
                     /locus_tag="VLL59_001418"
     CDS             12468..>13094
                     /locus_tag="VLL59_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509537.1"
                     /translation="MENKPAKASFFKLSSSKESNLKLFIEKMEEMFDNFRKKQYSNIP
                     TLEINDLMYYINAMQKVTSEEELNGTNLFYWLVTISRVDTESPIILANLEKNIDVRKR
                     EIEHGDNEGLVVDTRLLFDPFRQILVVYNQRGTINNYDLRRFFCQIIGVRGLKFDIIL
                     NSDAFKRVGKLDVVNSISYTVASPTNFKEFRDDTQSENADLKFANSMLG"
BASE COUNT         4783 a         2045 c         2711 g         3555 t
ORIGIN      
        1 cgcaattttt atttaaatta taccacagaa aattttaaag ctatgttgtt ttggataatt
       61 ccaaattaga aaggaggtgg gggaatgacg aaaatgacac taagagcctt acgcgttaac
      121 tatagcctta gcgcaaaaga agtagcgcaa gaacttggta ttcatcaaca aactttacta
      181 aaatacgaaa ttgatagtac ggacatcccg tttagtttat taaatgaatt ggcaaattat
      241 tacaatattg atgtaaataa tattttttta ggtaaaaaat tcgttttaaa acaaatgttt
      301 aaaaacaacc gcctacaaaa ctagaaagga cactatgcaa gcaaatcgaa ttttttacgg
      361 aaaagaaaaa ccaacaaacg cagtagcggg cgattgctgg tttagaaata acgaattaat
      421 gatactcaag aacaattggg aagctagcgt aaacgtcaac ggtttcgttg tgaataacgc
      481 ttaacaattc gttaccatcg gcgaaaatca ttttcgtaac ttcagcacct ttgataggga
      541 tgacttctct tccttctgct gaaggcgtgt tgtacgatac tttttcgcct aacttaaatt
      601 ggacatgaaa ataattagga cccatgcttt tttcctcctt tcgtaatgat agctttatta
      661 tagcacgcag gaggaacaaa actaataaaa ggagaaaaga aaaaatgaac tcactgaaac
      721 taagtatcaa accaaaatta gaacctaacg atgggcaatg cctgctatcg tcaggctatt
      781 cagtaaaaat taatgactgg gagcttggaa aaggtgtcgt agattttagg ctagaaatgc
      841 cagccgacaa aaaaccaaaa gccaccatca catttatacc aaaccttgtt gatatagatg
      901 ggatgatggc ggcaggtgtt cagggactat tgcctgaaag cgatattgac taacccgttg
      961 tagtagtgat tttcaatttt agctttaatc tgacctgtac taatcaaatg cttggcggta
     1021 tcaagtacat catcctgatc aaatgcatct gtttgaaaat catgaccaac accgactggg
     1081 atagttggtt caagagcggc gaactcaaga attttatcag ctatttcttt gctgaaagcc
     1141 atataatcac ctcccttcga gatgattata acaaaaaagt ccgacgggaa tcggactcaa
     1201 aacaaactta atttacttca ttataacaca agagagagga tattaatatg ccaaaagcag
     1261 aaattactta tagagcagtt gatgttaatg aaacagcttc tcatggtgat tataaacact
     1321 tgattcaaca atgggagggg ttgacagttg ctactgcaaa gcagtgggcg acagaaatgc
     1381 gtgatcatcc agactttaaa cagtttgtat taaatccaac gcatagaatc gtattcattg
     1441 attacgaagg attcaaactg tttgtacaat ggaaatctcg caatcgttat aaaacaaaaa
     1501 aagagtcact gccagaaatg cttgaaaata ttaaattcga aaaaagagta ggagtataac
     1561 atgaaactat tagattttat ttttgcaaaa ccaaaaaaac agaaaaaatc aaaatggacg
     1621 attgaaaata acggctggga agctaatgca cgtagatata accaaaagca cggtttacct
     1681 gctaaacaaa tttagtagga gacgcataac atgaatagaa taaaagagtt acgcaaggaa
     1741 aaaaaagtat ctcaaaaaga gatagcggat tttctaggta taagcgaaaa aacaatttct
     1801 cggtgggaaa acagcgaaaa cacaattaaa tctgacaagg caaaagaatt agcaaaatat
     1861 tttaatgtat cagtcgctta cctgctcgga tatagcgata ctacaaaaga taacaaagat
     1921 tttatcacaa tatctgtcaa agagtacaat gagcttaaaa aacaatcaga tgttttagat
     1981 ggagttattg agacgttaaa agacaagaga tcgacaagct acaaaataaa gtcatagctc
     2041 tgacaagaga aaacgataga ccgaaagccg aaaagtggca gttaaaacgt agaaagagga
     2101 aataacatgg cttatttata cgaattagaa ggcatttacg cacaattaca gtcaatggat
     2161 ttagacgaag aaacatttca ggacacgctg gacagtattg attttcaggc ggatttagaa
     2221 aacaacattg aatattttgt caaaatgtta aaaaatgctc aagctgacga agaaatgtat
     2281 aaagctgaaa aagaagcttt ttacgaaaag caaaaacaag cgcaagctaa aattgataaa
     2341 tacaaagaga cgatacattt agcaatggct ttgtctaata agaaaaaagt agatgctgga
     2401 atgtttaaag tgtcgctacg aaaaaacaaa aaagttgagg tgctggacga aacaaagatt
     2461 cctctcgaat atatgaccga aaaaattgag cggaagccag ataaaaaaga attagctaaa
     2521 ttacttaaaa ttggtcaaga aattgctgga gttgagttaa ttgaaactga aagtttacag
     2581 gtaaaataga tgaaaatcac taaagcaaca gaaataaaaa ataatgatag ttgttattta
     2641 atctatggta atccagggtt tggaaaaaca tcaactgcaa aatatttgcc cggaaaaact
     2701 attgtaatca atattgataa gtcggcaaaa gtccttagag ggaacgaaaa tattgatatt
     2761 gcggatatag atacgcataa aatttgggga gagtggttag acacagtaaa agagttacta
     2821 aatggagcag cgaatgatta tgacaacatc gttatagata atgtctccga gttatttagg
     2881 gcttgcctag cgaaccttgg gcgcgagggt aaaaatcatc gtgtgccaag tcaagctgat
     2941 tatcaacgag ttgactttac tattttagat agtctgcgag cgctactgca attaaataaa
     3001 cgcattgtat ttttagcttg ggaaacctct gatcaatgga ctgacgaaaa cggaatgatt
     3061 tataacagag caatgccaga tatcaggaca aaaatattaa acaacttcct tggacttaca
     3121 gatgttgtgg ctagattggt caaaaaaact acagacgatg gggaagaagt gagaggtttt
     3181 attttacagc catcagctag tgtttatgct aaaaatcgtt tagatgatcg caaagggtgt
     3241 aaagtggagg aattatttga aactacgtga ttatcaagaa gaattactaa cagccatcag
     3301 gaggtcatta gcgactggaa ataaacgaat aatcgtccag tcgcctccct agaagtggaa
     3361 agacagtcgt tatggcccat atcgcaagaa gcgctacgga taaaggaaac agagtattgt
     3421 tttttagcca cagaaaagaa atcaatgaac aggtagagag aacatttgca gcaaatggag
     3481 ttaactcaaa tctgttaact atcggtggtg tgcagtcgtt agtcagaaaa ctagacagtc
     3541 tctctcaacc agaggtgatc ttgattgacg aggcccacca cagtaaagcc aagtcttact
     3601 taaaaatcat cgaccatttc aaaaacgctt atgtattgat gttcactggg acaccagtca
     3661 ggttaaatgg agatggattt gatgacattg cggatgattt ggtagctggg aaatctgtca
     3721 aatggctgca agaacacggt aatatagcta actttaaata ttatgctccg tccatgattg
     3781 ataattctgc cctcaaaaaa agaggtggag agtttactaa ggattctgtt aatcaatcca
     3841 tgaaatcggt tatctatggt gatgttatta aacactatga aaagctagca aaaggaaagc
     3901 aagctatcgt ttatacgcac agcgtagaag cctctcattt agtctctgac atgtttaatc
     3961 aagcagggta tcaatcgcaa tcagtcagcg gtaaaacgcc taaaagcgaa cgagaagaag
     4021 ctatgcaagc attcagagac ggaaagttga gaatactcgt taactgcgaa ttgtttacgg
     4081 aagggataga cctgcctaat gttgatgttt gcattatgtt gagaccaact caatcgctat
     4141 cgctatactt gcaatttgct atgaggccgt tgaatccaag agatggaaag atagctatta
     4201 ttattgatca cgttggcaat gtagagcgtt ttggcttacc taacatggat agggaatggc
     4261 gtttagatgg aaagactaaa caaaagcaat ccactaagat tggtgaacct accacaaggg
     4321 tatgtgatga ctgttatgcc acgtattggt ccgatactcg tatctgtccg gaatgtgggc
     4381 atgaaaacga gttaacaaaa cgtgaaattg aagaaatcaa agaagctgaa ttacaagaaa
     4441 tatctgaaca aaaacaacta aaactaaaaa atagagttag tatctatcaa tcaccagatc
     4501 tttgtcggac gatggatgaa ctaaccgaat atcgaaaaca acatggatac aagccaggat
     4561 ggcagtatca cattgctaaa aaattaggaa ttttatatta aaaggagaaa cacaatatgt
     4621 ttgaaatcga ctactcacaa gctaaagaat tcgcttcaat tactgatgga acttacgaaa
     4681 cttttgttga aaaagccgtc caagatgcaa ctaaaaacgg cgcagacttt attaacatcc
     4741 atttcagaat tcgcaaagac ttccagcaag aatttcaaaa taacattatt tttcatcgta
     4801 tctttgccaa aaaagaagat ggtaaatatc caatcggggc aatcatgaac cttgcaaaac
     4861 aagctggaat tccagacgga actaagttta agtctttgga tgactactta aatcaattgc
     4921 tcaataaatg ccttaaaatt accgttaaaa acgaaacatc agagtataac ggtaatactt
     4981 acaataattt aaacgtgaaa cgtattgaga aatccgacat tcctacgatg gttaaccctg
     5041 tagaagaatt taaagaagac gatctaccgt tctaattatg agggggatga tagattacgc
     5101 aatctattat caacaaaagg gattttcagt cataccaatt tcaaaagatg gcaaaaaacc
     5161 attagtcgct tttgcggata aaccagcttt tacagagcat gagctacgtc ttatatggaa
     5221 agataatcct gatgcaaata tcgccttaaa aacagataca ttttttgtca tagatattga
     5281 tgtccataac gatgtcgatg gtctgaaaaa tctaagggaa tgggagcatg caaggttgat
     5341 accaaaaacc ttgcaagcaa ccacgcctag tggaggacgg catatctacc taaaaaaacc
     5401 aaaaggtgtt tccatggcgc aaaatatcgg ttttattgat ggcgttgatt tgaaggctca
     5461 tgttaacaat tatgtgctgg taccaccatc aaataatgcc aaaggcatgt atgagtggga
     5521 tatggtgcat tcgccaacct ctggcgaaat gaccgaagcg cctcttgagt tgataaatgt
     5581 attgcgagaa ttaaaacctg cctatgaata tgatgccagt agttttacat ctggagatta
     5641 ccaaggtagc aataaaacag ctaaattatt tgagacgatt gtccttggtt ttggtgatac
     5701 aggcggccgt aataatgctt tagctgaatt tgtaggaggt ctattgctta gaaatgtaga
     5761 tgttgaaata gcttacacat tagctaaaat ggctaaccat aaaactgcgg accctttaag
     5821 tgataaggag tttgaaagaa cgtttaaaag catgtgtgat aaggagttga ggaggagaag
     5881 tggattttga attttacaga gaaaaattaa atgaggaacc tggcattgaa ccaggtaaac
     5941 ctaaaacatg gtctgctatt aaatccaagc tggtagcata ccgaagagag tggttagaag
     6001 aagctggtaa agatgttaaa aatctatcag aactagcggt cgccatcgga attaataaat
     6061 tcctgcatgt tattacctta gaaaacggga aagtggctat ctatgatcca gaccaaggat
     6121 attacatcaa ggactataaa tttgcttata aattgatcca tattttacaa cctacgttta
     6181 atgaaacgaa atgtcgcaac gttttgttta tgttagcaag tatggacagg aaatatgggg
     6241 caatggactt cgaaccagaa taccaagacg taagacggta tgtgttagtt aaaaatggca
     6301 tttatgacaa aaaaaataag gcacttttac cttttgatca ccgatttatc aattttagca
     6361 ctattgaaac agaacttatt ccgaacgctc ctctcccaac cattgatggt tgggacgttg
     6421 agtcgtggtt actagattta atgagcggag ataaagacct cgtccagtta ttatggcaag
     6481 tcgtggcagc atcgttaaat ggtaattatt cttatcgtaa gtccatttgg ttcgtgggag
     6541 atggtaatga cggtaaaggg acgtttcagc agatgatcag taatctggtt ggttttaaaa
     6601 atgtcgctcc tctgaaatta aatcaatttt cagagcgctt cggtcttgcg attattgagg
     6661 ggaaaacggt gattatcgga gacgatgttc aagctggtat ctatgtagac gaaagtagca
     6721 actttaattc agtcgtgact ggagagcctg tcagtatcga aaaaaaaggc gagaatcctt
     6781 acatggcgat attcaaaaaa accgtcatac aatcaacaaa cggaatgcct gtatttaaaa
     6841 acaaatcaaa cggtacttat cgtcgtatta tcattattcc gtttaaaaaa acattctctt
     6901 ccgcagaaga taattgggcc attaaagacg attacatcaa tagaagagag gttcttgaat
     6961 acgttctatg gaaatctatc aatttagatt ttgataaatt ttatgagcct aaggttacac
     7021 aggatcgtat gagggaattt aaggaagaaa ataacacgat tctcaaattt ttaaatgagt
     7081 atttagaaga tgttgaatcg acaagattgc ctgtacgttt tttgtgggat gtttaccaat
     7141 cttggtgcac agaaaacggt gtaacaaagc ccaaaaaatc aaattttgaa aaagaactag
     7201 caatcaattt gccagacggt tgggaaaaaa ccaaaagtaa gccattaaac tactttaagc
     7261 ctatcaacga taaaccttat tattggattg actacaattt tcaatgggat gatagtaaag
     7321 atggtaaaaa aacagcagta attgttcaaa aaagttacta ggacaccgga ggttaccgca
     7381 accggtaacc gttaaaaccg ttgggagagt aaggataaag gcctttggtt accgagttac
     7441 ttctatttct ctattttaat aaaaaataat aataaatata tatataaaga gagttgaaaa
     7501 atgcggtaac tcggtaacca aatcaccaaa tagcttggga gagtaaggag gagaaggaca
     7561 ccgcaaccgg taaccaagtg agtaaccggt gtccgaaata attatatgac aacagaatca
     7621 ctaatccaaa accaaatccg tgttgctcta tcaaaagcgg gccatatggt ttttagagct
     7681 aacgttggta aagtcaaaac agtagacggt agattatttg atacgggact acctaaaggt
     7741 ttttgtgact tgtttggatt taagccagac gggcaaatat tcttcattga agtaaaaaac
     7801 gaaacaggtc gagtaaggcc tgaacagaaa aattttatgg aggtaatggc atctagggga
     7861 gctctggtag gagtagctag atctgtggaa gatgccttaa aaatagtcaa tgacactagt
     7921 agatgatttt tacaaacaaa tggagccgtc aatcaaagcg tttttagacg ataacattac
     7981 catcgcagat gaagaagaag ctgacagagt ctatagatct gtcaaatact ataaaaaact
     8041 aaacagattg ccgccacctg atgtattgga gtggttccaa cgaatctaca cgacagagaa
     8101 aatggtggcg ttaatcaagc agtcttaccg tcttaaacaa aaaaagacag acgaggatga
     8161 caagatttac gaaaagtgga tgtttaaaaa ctacggtgac gttaagctcg ttaaaaaaat
     8221 caaacgcatg gacgcactag aaagagctcg gagaatgggt ctatgaaaag acacagacag
     8281 tggcataacg atattaaata tacacctaga tcttacgata atctgttgcc ttacgatata
     8341 tcagagctgt taatagctca cagatgcaaa ataaagatgt ctgatgaggt tttagcagac
     8401 aagataggta tttatacttg gcaattaaaa gcgctcttag aacgcagaat attgccaaat
     8461 gagagcgagt gtaaattgat tataaatttt ttgagagagg tggaaggatg acgacagatg
     8521 aagcgttgca aaatttacgt gatgacttga ataaaataat taatgtccta aaaaacgact
     8581 ggaaagcact attatttctt acgattgcaa tatttgggat gatggtgacc gtgtcgtatt
     8641 ttagctatcg tgatgcacga caatattacg agccgcaaat atacggacta cgtacacagc
     8701 taagtaggac acaaaagcag cttaaacgtg ctagcgagga tagaactaga cagactaagc
     8761 ggatagcgga aatgactagg aatggaggat aaggatggat tatttaatga ttggaataat
     8821 agtattatca gtagtaattt ttataatggg atttttcata ctttactatc aagcaataat
     8881 tgttaattcg atgaaaaatg attttcgtag aatgcgtaaa gaattgagag aagaactcgg
     8941 ttttgatagc tataactggt ctgacagttt cagaaatatg cgtagagata ttaaatcaaa
     9001 taaagagtta atatccgaaa taaactcttt gcaaatcata aaaaaagcca aagaagctaa
     9061 acgactagaa gaactcgagc agacaaaagc aaacgtcgaa aaagaaatca ataagttgaa
     9121 tgggggatga gaatgacaga catcaagatt ttagatgctt gttgtggaag tcgcctattt
     9181 tggtttgata aaaacgaacc tcacacaact tttatggacg tcagacaaga aaaatttgag
     9241 atgcacggca aaaaaatcaa tgtcaaccct gatgtaattg gtgattttcg tgacatgcct
     9301 tttgaaagta atagctttaa cctggttgtc ttcgacccgc cacacttaaa atatgttgga
     9361 caaaactcaa ttatgaaagc ccagtatggc caacttgata aagaaaactg gaaagaagat
     9421 atttcaaaag gtttcgaaga gtgtatgaga gttctaaaag taggaggaac tttagttttt
     9481 aaatggtctg attgccaggt taatgtaaga gaagttttat cagcaattcc atttaaaccg
     9541 ctttttggtc aacaacgcgg gacaactcac tggatgacat ttgtaaagtt tgctgaactg
     9601 acagggaacg ggagatgaaa aatgaacaaa caaaactttg aaaaactaga taaagttaag
     9661 gaattacttg acgaactaaa aattccagaa tttatggcgc cacttttagt tggcaatcag
     9721 attatggaaa ttatcaacga cttacataat gaaccagatc aatttggagc acaggtgtta
     9781 ctaccatcgc cagacaaaaa atataagttt gcagtgcgaa tttgtcgaga agaaaattta
     9841 gaggattgag ttaacgaaaa tgggggatga ggaaatggca gtaacaaata gcagagatga
     9901 ttttttaaaa ataaatgact ctattattta ttgaggagtt gacgaaatga aaaacgaaaa
     9961 ttttttaggt tatgatctag ctgaactatt agaagaaaaa ttagtaggga aacgacttaa
    10021 atcaatagac gacgaaaaga ttgtacttgc cgatgggaca gtaataaaaa ttgaattaaa
    10081 cgagggttgt ggaggctgtg gaaatgggtg gtcagaatta aacatcacga cagaaaaccc
    10141 aaacttggaa tcagctgtaa tgggcgttga atacacagaa aaatatagtg aatgggatga
    10201 tgaattcaaa atttttgtct acatgacaga caattctgtt attgagattt acggatatga
    10261 cggtgttggt aatggatatt atggatatgg tttctgggtt actgtgaaga atcctggtga
    10321 tctaatagaa tctgaattgg aggactaatg ctaactacaa atcaaataca caaactgctg
    10381 ggagtaaaag aagtctacaa agcgcctgac acgttgataa aaataatttt agacaaggaa
    10441 aagcgcgagg acttattcag acagtttttg aaatatgaaa cagatgtatc ttacgactgg
    10501 tttatgcaat attttgagga agaacaagct gaccgcaaaa ataaaaagca agactttacg
    10561 cctaaatcgg ttagtacact attatctaaa ataataagtg gtaatcaata ctacgaggta
    10621 gcagtcggga cgggtgggat acttatccaa gcatggcaag aacaacgatt aaatgacagt
    10681 ccatttactt atcgtccgag taaatactgg tatcacgtag aagagttatc ggacaaagca
    10741 gtaccgtttt tactatttaa tatgtctata agagggataa atggtatggt ggtgcatggt
    10801 gactctttaa caagacaagt taaaaatatt tattttttgc aaaatacaaa agacgacatg
    10861 ctgagtttta gtgatattaa cgttatgcca aggactcaag atattgagcg agaatttaat
    10921 gtcaaagagt ggattggtga tgggatagaa cacattgaaa atccactaat tgaatggata
    10981 taaccaataa cggtatcacg cacgttcgac tcgtgcggtt ggtattgacc gaaattaaaa
    11041 aatagaaacg agaacctcct tacaccaaaa caaatctaac gcagattatc ggtcatttgt
    11101 tattattcaa ggcgctaata ctgacatcgt acgcctgtgt caaaaataaa aaaagaaaga
    11161 gagggctttt ctccacaaaa caaaaagacg tccacacgga acgccccctt ggttaaattt
    11221 aagcttaaat aaattatacc atattggggg ctttcatgac gttttttcct gagattgata
    11281 tccaaaaaac aaaatccaat gccaagcgta aattgagaga gtatccacgc tggcgaagga
    11341 tagctaatga cgtagatact caaaaagtta cagctactta ctcatttgag ccaagacaac
    11401 cgcatggagt tcctagcaaa ccagttgaga gactagcact aaaccgtgtg tcagcagaac
    11461 aagagctgga tgcgattgag agagcagtca acgggatatt tgatccagag tatagattga
    11521 tactgattga caagtatttg ctcacatatc caaagactga ttgtgatatt tatacaaaac
    11581 ttggttatga aaaaagccag tattacaaca tgctagataa tgctttattg tcgttctcag
    11641 agctatataa agagggaatg ttgcttgtcg agaaattgga aaaaagctgg aattaatatg
    11701 gaataattat gtactttata tataattatt catgttatta tagtactatc aaaataacaa
    11761 gaagagataa ccttttaacc actggctatt catttagtcg ccaactttaa ctacaatcaa
    11821 acttgttatt ttgtagcctg atggcggtac agcgagttga gacgacaact gggtatgcag
    11881 gttcgattcc tgccgtctca atcagcgccc agaagaggcg cgacccagta tcccgaaagg
    11941 cagtcacgca ctgatatact ggtttttact tggttgatag tcatattcct accaatgacg
    12001 attggtaaaa aagatacata gatcggctgt atagtctacg tgtacgtatt cacaacagat
    12061 tgactcattt gattaaccac aagtaaaaca agggtcgcaa ccttgcttgt ggttagtaga
    12121 cctagtggtc gtttatgcac gttcgattcg tgcaaggtct gtttgtagct atgtacggat
    12181 aaataatagc cttagtgtcc ttcgggagct aagtcgtact aaatgctaca aaattggaac
    12241 atgaaccgtg attggaaaac ggtggaggta gcgccttgct tcgggacgtt agctaagtcc
    12301 gaaaactctt tgcgaagagc cagaagaaga tgtgtcggtt cgattccgac tgttcctgtt
    12361 gcatttaatg caaactccat atttttatta aaaaagccta ttatacctat tgtgtaaggg
    12421 cttttttcgt tgtattattg aagtgataaa aaatatggag attaaatatg gaaaacaaac
    12481 ccgcaaaagc aagtttcttt aaattaagtt cttctaaaga atctaattta aaattgttta
    12541 tcgaaaagat ggaggaaatg tttgataatt ttagaaaaaa acaatatagt aacattccaa
    12601 cattagagat aaatgatctt atgtattata taaatgcaat gcagaaggta acaagtgaag
    12661 aagaattaaa tggaacgaat ctattttatt ggttagttac catttcacgg gtggatacag
    12721 aatctccaat tattcttgcg aatcttgaaa aaaatattga tgtaagaaaa agggaaattg
    12781 aacatgggga taatgagggc cttgtggttg atacaagatt attatttgac ccatttagac
    12841 aaattttagt tgtttataat caaagaggta caattaataa ttacgactta agaaggtttt
    12901 tttgtcaaat aattggagtt agaggattga agtttgatat tatattaaac agtgatgctt
    12961 tcaaaagggt tggtaagctt gatgttgtaa attcaattag ttatactgtt gcaagcccaa
    13021 caaactttaa ggagtttcga gatgatactc aaagtgaaaa tgccgattta aagtttgcaa
    13081 attctatgct agga
//
LOCUS       DAUNLR010000049        12659 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUNLR010000049 DAUNLR010000000
VERSION     DAUNLR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12659
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.049"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            3..641
                     /locus_tag="VLL59_001419"
     CDS             3..641
                     /locus_tag="VLL59_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6509538.1"
                     /translation="MSPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIASTF
                     NVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIRE
                     TINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWHQ
                     TGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(784..1326)
                     /locus_tag="VLL59_001420"
     CDS             complement(784..1326)
                     /locus_tag="VLL59_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HER6509539.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAKIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            1444..2145
                     /locus_tag="VLL59_001421"
     CDS             1444..2145
                     /locus_tag="VLL59_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509540.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            2160..4796
                     /locus_tag="VLL59_001422"
     CDS             2160..4796
                     /locus_tag="VLL59_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HER6509541.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDC
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            4888..5484
                     /locus_tag="VLL59_001423"
     CDS             4888..5484
                     /locus_tag="VLL59_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HER6509542.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            5495..6451
                     /locus_tag="VLL59_001424"
     CDS             5495..6451
                     /locus_tag="VLL59_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HER6509543.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            6548..7905
                     /locus_tag="VLL59_001425"
                     /pseudo
     CDS             6548..7905
                     /locus_tag="VLL59_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
     gene            8021..8905
                     /gene="truB"
                     /locus_tag="VLL59_001426"
     CDS             8021..8905
                     /gene="truB"
                     /locus_tag="VLL59_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HER6509544.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QMMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGKKV
                     IAILEKRDQEYKPKKVLI"
     gene            8934..9866
                     /locus_tag="VLL59_001427"
     CDS             8934..9866
                     /locus_tag="VLL59_001427"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HER6509545.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLTRNFEGQVYTIKEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            9909..10313
                     /locus_tag="VLL59_001428"
     CDS             9909..10313
                     /locus_tag="VLL59_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HER6509546.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDVDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            10315..10593
                     /locus_tag="VLL59_001429"
     CDS             10315..10593
                     /locus_tag="VLL59_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HER6509547.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            10583..11371
                     /locus_tag="VLL59_001430"
     CDS             10583..11371
                     /locus_tag="VLL59_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HER6509548.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            11374..>12659
                     /locus_tag="VLL59_001431"
     CDS             11374..>12659
                     /locus_tag="VLL59_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HER6509549.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKN"
BASE COUNT         4037 a         2180 c         2635 g         3807 t
ORIGIN      
        1 tgataagtcc taaaaaagag ataacaagtt caaaatatca aaaaattgct atttcagtag
       61 ctcagcgtat cgcaaatggc gaatatgaag tgggcgaaaa gttaaagtca agaactacta
      121 tcgcctcgac atttaatgta tcacccgaaa cggctcgtaa aggcctgaat attttagctg
      181 acttgaaaat tttgacttta aaacatggta gtggagctat tgtgctgtca aaagaaagag
      241 ctattgagtt tataaatcaa tacgaatcaa cccattccat cgctgtttta aaagaaaaaa
      301 tacgtgagac tattaatgat cagggaaaag caatggaaaa aatggctgtt ttggtcaatg
      361 attttttaat gcaaagtcaa tctgttagta agcaataccc attagcacct tatgagatta
      421 tttgtagtca agattcggaa cattttggca aatctatcgg tgtgttaaat atctggcacc
      481 agacaggagc aactatcgtc gctattgaac atgctggtca gtttatcgtt tcaccaggtc
      541 cttattctgt tattgaaaaa ggcgatcata tttatttcgt tggtgatgag tcagtcattt
      601 cacgaatgaa gacctttttt aatttacgaa aaggattata agtttgaggg cccacctcaa
      661 actttttttg ttgctgttga gcattattaa aagaggcaga tcatcatggt ttgtctttcc
      721 aaaatatctg tttagacagt tgttttggat tgggagcatg atttcagact cttttgatgt
      781 tttttaattg tctagagtaa ctgctttgag aataatatcg gcaacctctt cagtggtttc
      841 ttgatagcca ttagcaatcc aatagctgat aatgctctca atactggcaa ggtaaacttc
      901 taaagcatag ggataaggaa tatggtattg attggtcaca atgtcttgga aaccagtaat
      961 agtagtcaaa aattggtaac agaaatcctt gatgagttgc ggaaatttga ggtaagaaat
     1021 agtagcgagt gcggttataa attctctatg ttctataagg taggacaagg tttgattgag
     1081 gacttgtcga gtgtctgtgt agattttagc ctgatttaac aaacggtaca aatcatccag
     1141 agtgtcattt ttgaagtgat tcatcatgtc aaatttatca gtgtagtgga ggtagaaggt
     1201 tcctctattg ataccagcct ttttagtaag gtcagagaca gtaagagttt caaaagattg
     1261 ttcagttagt aaggtggtta aggcggtctt tacataagct ttggtttcag tatgtctttt
     1321 ggtcattctc aggtgctcct taaatcaaca gttgcgtcag atttgttctt gttaaatact
     1381 tagggccatt atataataag gctataatta aatcaacact atgttcaaat aatggagggg
     1441 cagatggctt ttattgaatt aaaacaggtt tcaaaatctt atcaggtagg agagacgact
     1501 gtttttgcca accacgaagt gtcttttgag attaataaag gagaactagt ggttattttg
     1561 ggagcatccg gagctggtaa atcgacagtc ctcaatattt tggggggcat ggacacagta
     1621 gatgcaggtc aagtaattat tgatggcaaa gacattgctc attacacgtc taaggcctta
     1681 actcagtatc gtcggaatgc tattggtttc gtttttcaat tttataattt ggttcctaat
     1741 ttgacagcta aagaaaatgt tgaattagca gttgaaattg tagcagatgc tttagatcct
     1801 gtgaccattt taaaggaagt aggactcagt catcgtctgg atcattttcc tgctcagctc
     1861 tcaggtggtg aacagcaacg ggtttcgata gcacgtgcct tagctaaaaa ccctaaattg
     1921 cttctttgtg atgaacctac aggtgccctt gactaccaaa caggaaagca aattctaacc
     1981 ctcttacagg atatggcacg aactaagggg accacggtag ttattgtaac ccacaatgct
     2041 gctattgctc cgatagctga tcgtgtcatt tttatgcatg atgcacaggt taccaagaca
     2101 gtcattaata aggaacctgc aagcattgag acaattgatt attaagagga aggtgtcgta
     2161 tgataaagaa aaccttatgg aaggatattt tgagagctat caagaatagt aaagggcgat
     2221 tcatttcctt atttttccta atggccttag gctcctttgc tttagttgga cttaaagtca
     2281 ccggtccaga tatggaacga acagccagcc gttacctcga aagacaccag gtgatggacc
     2341 taacggtact ggcttctcat caattttccc aagccgataa acaagagtta gatacgttaa
     2401 aaggggctca tttagaatat ggtcatttac ttgatgtcag tctaactagc aaccagaaat
     2461 ctcttaggct ctatagcgtg ccaaagaaag tgtctaagcc agtcttggtt aaagggagtt
     2521 ggccaaagcg agagacagat ttggttttat cctcctcact tgctaaaaac tatcagattg
     2581 gagatgaact agcagtcacc tcacctatgg aaggtttgct gacgacaacc cattttcaag
     2641 tggttggttt tgcgaattct tcagaagttt ggtccaagtc caatttagga agttcctcaa
     2701 ccggagatgg aagtctctac gcttatgctt ttgttaatcc aaacgttttt aaaagtgcct
     2761 ttaacctgct gcgcatccgt tttagtaatc ttcgtctgac aaacgctttt tccaaagact
     2821 atcaaaaaag ggtaacccaa aaccaagctc atttggataa tctacttaaa gataatggcc
     2881 agaagcgtta tgatgacctc caaaatcagt atgaccttgc cttaaaaaat ggcagagcag
     2941 cacttgcaaa ggaaacagtg aaactagctg cgagtgagga gaacttaact tttttagaag
     3001 gctctgcttt acaagaagct aagcatcaga ttgaacaagg caaacaagca ttagccaagg
     3061 aggaaaagca gttagagcag gtgcaggcta caaaagataa gctagaaaaa cccagttacc
     3121 tgacttataa tcgctcgacc ctaccaggag gagaaggata tcatacttat gcaacttcaa
     3181 cgacctccat ttcaaatgtt ggaaatattt ttcctgttgt tctttatctc gtagctgctc
     3241 tagtagcctt taccaccatg acacgttatg ttgatgaaga aagaacaagc tctggtctat
     3301 taaaagccat cggttattct aacaaggata tcagtttaaa gtttcttatc tatgggcttt
     3361 tagccagttt tttagggaca actttaggta ttattggggg aacttacctc ttatctgcct
     3421 tgatttcaga gatcttaaca ggagctttga ctattggaaa gactcacctt tatagttatt
     3481 ggttttataa tggcatagct tacttgctgg ctatgttatc tgctgtttta ccagcctact
     3541 taattgtcaa aaaggaatta ttcctcaatg cagctcagtt attgctgccc aaacctccta
     3601 gtaagggggc aaaaatctgg ttggaacacc ttacttttgt ctggaaagcc ctgtccttta
     3661 ctcacaaggt gaccatacgt aatatttttc gctataaaca aagaatgctg atgaccattg
     3721 taggcgttgc aggctctgta gcccttttat ttgcaggctt agggattcag tcgtcattag
     3781 ccaaagtagt tgagcatcaa tttggtgatt taacgactta tgatattttg gctgtcggtt
     3841 cggccaaagc gacagcgaca gagcaaactg acttagctag ctatcttaaa caagaaccta
     3901 ttacagggta ccaaaaggta tcttatgcca gcttaaccct tcctgtaaag ggattacctg
     3961 ataagcaaag tatttccatt ttatcaagtt cagctacctc tcttagcccc tattttaatc
     4021 tgctggattg tcaggagcaa aagaaggttc ccattccaac ctctggtgtt ttgatttctg
     4081 agaaattagc ctcttattac aaggtaaaac caggtgatca gttggtattg actgatcgga
     4141 aaggacagtc ttataaagtg acgattaaac aggttattga catgacagtt ggccattacc
     4201 tgataatgtc taatacctat tttaagaatc attttaaagg attggaggct gctcctgcct
     4261 atctgattaa ggtaaaagac aaagatagca agcacataaa ggagacagcc agtgacttgt
     4321 taaccttaaa agcgattaga gcagtttcac aaaacgtcaa tcatattaaa tctgttcagc
     4381 tagtagtcac ctctcttaat caggtcatga ccctccttgt cttcttgtct attttattag
     4441 caatcgttat cctttataac ttaacgacta ttaatattgc tgagcgtatt cgagaattat
     4501 ccactattaa agttctggga ttttacgatc aggaggtcac cttatatatt tatcgagaaa
     4561 ctatttcgct atccctagta ggcattcttt taggtatcta tttaggaaaa ggcctgcata
     4621 cttatatcat gacaatgatt tcaactgggg atattcaatt tggtgtaaag gttgatgctt
     4681 atgtttatct agtgccaatt ctagtaatcc ttagcttgtt agcggtatta ggtatctggg
     4741 ttaatcgcca tttaaaaaag gttgatatgt tagaagcttt gaaatccata gattgattgg
     4801 tgaaaagaca gatatagaca gcacttgaaa agttaatcat attatgatag tatctaaata
     4861 ctataattta atagaaagat actatgtatg gaaaatagca ttgaggccta tctagcagat
     4921 agcagagaaa aggtaacatt aggtacagtt gttgattgtt ttaaaggaaa agcagtctca
     4981 agtaaggttg tgccaggtga tgtgggattg attaatttat ctgacatggg caccttaggg
     5041 attcaatatc accaattaag aactttccag atggatcgta ggcagctctt gcgttacctt
     5101 ttggaagacg gagatgtctt aatcgcctct aagggaaccc taaaaaaagt ctgtgttttt
     5161 cataagcaaa atcgagatgt ggtggcatca tcaaatatca ctgtcttacg ccctcaaaaa
     5221 ctgttaaggg gctactatat caagttcttt ttggactcac ctattggtca agcgctcttg
     5281 gatgcagcgg accatggcaa agatgtgatc aatctctcaa cgaaagaatt gttggatatt
     5341 ccaattcccg ttattccttt agtgaaacag gactatttga ttaatcacta cttgagagga
     5401 ttaacagatt atcatcgtaa actcaatcga gcagaacagg agtgggaata tattcagaat
     5461 gaaattcaaa aaggattagg ttaggagtct tgtcatgggt tcagttgaac gtacattaaa
     5521 aatgaccttg gctaccattg ttgccatttt aattgcttac caacttcatc tggattatgc
     5581 aatgtcagcg gggatcattg ccctgttaag tgttttagac acccgtaagt ccagtttggt
     5641 ggtcgctagg aatcgcttgc tatctttttt cctggctttc gggattgcga tgatgtgctt
     5701 tagcttgttt ggttttacga cagtaggttt tatgtgttat ttgttaatta ttattccttt
     5761 gctctatcac tttcagatag aggcaggact ggttcctata acagtacttg taacacattt
     5821 gattgctaaa aaaagtattg cattacctat tttatcgaat gagtttatgc tcttttttgt
     5881 agggactagt gtcgctttac tatttaatgc ttatatgggt ccacaagatc agcaaattcg
     5941 gtactatcac caaaaagttg aatcggatct gaaaggtatc ttataccgtt ttgaaagttt
     6001 tctactggaa ggaaaaggtc aaaatgaagg gctcttgatc aaaaaccttg ataaaatatt
     6061 agatgaagct ctaaaactag tttatcgaga aaggcataat caactatttc agcagaccaa
     6121 ttatcaagtt cattattttg agatgcgacg acaacaaaat agactattgg gacaaatggc
     6181 tatcaacgta aacacgttaa tgagacaaag taaggaaagt attcttttgt cacatctttt
     6241 tcacgaaact gcttgtcagc taagcgaaca aaatccggct ttaaccttga ttgatgacat
     6301 cgaacaattg cttgaaacct ttcgtcatgg tgatcttcct caaactcggg aggaatttga
     6361 gcgacgtgcg gttttatttc agctcttaca agacttagag cgctttatct tattaaaggt
     6421 agagttttat caggattatc aaaatgacta aatctctatt gcacacttct tatctatgac
     6481 agcttgggac ttaacttcct gagctttttt gctataataa aaagaagaat ctcagaatgg
     6541 agacaagatg aacgaaataa aatgccctca ttgtcatacc ctatttacta tcaatgagtc
     6601 agagtatagt caattattgg aacaagtcag agggcaagcc tttgatgaag aattgaaaaa
     6661 acggctaatc aatgagatag ccttgctgga agaaaaagcg aagcatcaat tgcatgaggt
     6721 tgtcgcaaaa aaagaaacag ctattaccag cttgacaaac caattagagc aaattgaaaa
     6781 agaacaagcc tacctcagac aagaagaact ggctaaaaaa gaccagctta ttgcttcttt
     6841 agaagcgaaa cttgataaat tagcctcgca aaatgctttg gaactggcca atcaattagc
     6901 tgagaaggac aaagaagtgg ttagtttgac caatcagctg gacaagttag cacttgaaaa
     6961 agatgccacg ttccagtcaa aacttgctac aatcgaaaaa gaacgcgatg gaatcaaaaa
     7021 tcaattggcg cttcaagcta aagaaagtga attgtcgttg gcttcggtgc gcagcgacta
     7081 cgaagcacag ttaaaagcgg ctaacgagca agttgaattt tataaaaatt tcaaagcgca
     7141 gcaatctacc aaagcaatcg gagagagtct agaactctat gctgaaacag agtttaacaa
     7201 agtaagaagc tatgctttcc ccaatgctag ctttgtcaaa gataaccaat tgtctagtcg
     7261 tgggtcaaaa ggggactata tttaccgaga ggttgatgcc aatggtgtag aaatcctctc
     7321 tatcatgttt gagatgaaga acgaggcaga caccaccaaa acaaaacata aaacaaaaca
     7381 aaacataaaa atagtgattt tttcaaggag ttagataaag accgtcgcga aaaagattgt
     7441 gagtatgctg ttttggtaag catgttagaa gctgataatg attactacaa tacagggatt
     7501 gttgatgtca gtcatgagta tcaaaagatg tatgtggttc gtcctcagct ctttattcag
     7561 ttgataggga ttctgcgaaa tgcggccctg aatagtttac attataagca agagttggcc
     7621 ttggttaagg aacaaaatat tgacatcact cacttcgaag aggatttgga ccaatttaag
     7681 aatgcctttg ctaagaacta tcagtctgcc agcaacaact ttaaaaaggc tattgacgag
     7741 attgataaat cgattaaacg catggaggaa gtgaaacgct ttttaaccac tagtgaaaat
     7801 cagttacgct tagctaataa taaattagag gatgtttcag ttaaaaaact gacccgccaa
     7861 aacccaacca tgcgagagaa atttgaagcc ctcaaggacc agtaagcctg aaagtgagtc
     7921 tttccctgct aaaattggtt aagcgtttat tttggcaaaa ctgatgataa agcggtagaa
     7981 tagaatcagt aacaattact aattagagag aaaaatagac atgataaatg gaatcattaa
     8041 tttaaaaaaa gaagccggca tgacctctca tgacgcagtt tttaaattac ggaagttatt
     8101 acaagaaaaa aagattggac atggggggac cttagatcct gatgtggtcg gtgttctacc
     8161 aattgcagtt ggtaaggcta ctcgtgtgat cgaatacatg acagaagctg gtaaagttta
     8221 tgaaggacaa gtgactctcg gttactcaac aacgactgag gatgctagtg gagaggtagt
     8281 tgcgagatct tctttgccag ctgtgctaac agaagaactc gttgatcaaa tgatgacgac
     8341 tttccttggg aaaatcacac agaccccacc tatgtattca gccgtaaagg ttaatggccg
     8401 taaattatac gagtatgcgc gtgctggtga aagtgtggaa cgtcctagaa gagaagtgac
     8461 catttctctg tttgaacgca ccagcccttt gaattttact gaagacggtc tttgccgatt
     8521 ctcttttaaa gttgcttgta gcaaggggac ttatgtgcgg accttagcag ttgatttagg
     8581 tcgagctcta ggggtagaga gtcatatgtc cttcttgcag cgatcagctt cagcaggatt
     8641 aaccctcgag actgcctata ctttgggaga aattgctgat atggtttcta aacaagagat
     8701 gtcttttttg ttaccgatcg agtatggcgt tgctgatctt cctaaaatgg ttattgatga
     8761 tactgaattg actgaaattt catttggtcg ccgtcttagt ctccctagtc aagagccact
     8821 gttagctgct tttcatggca aaaaagtaat tgctatttta gaaaaaagag atcaagaata
     8881 caaacccaaa aaagttctta tttaaatagt ttgagtaagt agaatggata attatggaaa
     8941 ttgaatatat caaagattat cgtgatatta accaagaaga tgatacagtc ttggtattgg
     9001 gatattttga tggattacac cgtggtcata aagccttatt tgacaaagca agagaggttg
     9061 caaataaaga agggttaaaa gtagtcgttt ttacgtttac agagtctccg aaattggctt
     9121 tttcgcgttt ttctcctgag ttattgcttc atattactta tccaaagaag cgttatgaaa
     9181 aatttgccga ttacggtgta aataaattat atttggttga ttttacttct aaattctcta
     9241 aggtctcatc tgatcatttt ataactcatt atattaaaaa cctgaaagca aagcatattg
     9301 ttgtcggttt tgactataag tttgggcata attgtacaga tagtgattat ttaaccagaa
     9361 attttgaagg acaagtttat accattaagg aaataaaaga agatcatcga aaaatttctg
     9421 ctacatggat aaggaagctt attcaagaag gtaatgtagt taaagcaaac cacttgttag
     9481 gctatgactt atcgacaagg gggagagtcg ttcacgggga tgcgcgtggc cgtactattg
     9541 gtttcccaac agccaatcta gctccaattg acaacacata cttaccagct gatggagtct
     9601 atgttacaaa tgttattgtt gctaataaaa tctatcgctc tatgacgagt ttaggtaaaa
     9661 atgtgacatt tggggggaaa gagttgcgtc tagaagttaa catttttgac tttgacgaag
     9721 agatctatgg agaaattatt gagattgttt ggttagataa gattcgagac atggaaaaat
     9781 tcgagggaat cgaagatttg actgatagat tggaatatga taaacgaaca gcattaaatt
     9841 ggaaaaaaga tagcaaatta tcttaaattt ttgtataata aggtaagtaa atttgataga
     9901 ggaaaaatat ggttacctta tttttatcac ctagctgtac cagttgtcgt aaagcaaggg
     9961 catggttagt aaaacacgaa gttgactttc aagagcataa tattattaca agtccattaa
    10021 gccgtgatga attaatgtca atcctctctt ttacagagaa tggaacggag gatattattt
    10081 caacacgttc aaaggttttt caaaaacttg atgttgatgt agaagagctt tcaatttcag
    10141 atttaattga tttaattgct aaaaatccaa gtcttcttcg tcgccctatt atcatggatc
    10201 aaaaacgcat gcaaattggt tttaatgaag atgaaattag agcgttttta tcgagagatt
    10261 atcgcaagca agaactacgt caagcaacga taaaagcaga aattgagggg tgatatgtca
    10321 ggtaattatt attatccact tgacttaagt tggagcactg aagaaatatc ctcagtgctt
    10381 cattttttga ataaagtgga gttagcatat gaaaaaaaag tagatgcaaa acaactccta
    10441 gatagttata agacttataa aaccattgtc aaaagtaaag ctcaggaaaa gcaaatcgac
    10501 cgtgattttc aaaaagttag tggttattcg acctatcaag ttgttaaaaa agcgaaggca
    10561 attgagaaag gattcttttc ccttggaaac taaatacgca tttgcaaggc aaatcattaa
    10621 agaagcaggg ctttttatca agtcaaaaat gtcagagcag ctagatattc aggtgaaaac
    10681 acaatttgat gatctggtta ccaatgttga tcaagaaact caacagttac tgatggatcg
    10741 tattcatcag acctatcctt gtgatgccat tttagctgaa gaaaatgacg ttcgtcaccc
    10801 cattaatcaa ggaaatgttt gggtcatcga tcccattgat ggaacggtta actttattgt
    10861 gcagggatca cagtttgcag tgatgattgc ctattatgaa caaggaattg gccaatttgg
    10921 gcttatttat gatgtgatgg cagatcaatt actagctggt ggtggtgatt ttgaagttac
    10981 tttaaacggt gataagcttc cagcttacca agaaaaacct ttagagcgta gcttaattgg
    11041 ctgcaatgca ggcatgtttg ccagaaatga tcgtaacctt gctcatctaa ttgcaaagac
    11101 tttaggtgta agggtttatg gtggtgcagg tatctgcatg gttaaggtca tgaagcagga
    11161 attactggcc tatttttcat ttatccaacc atgggattac gcagcagcaa aagtactagg
    11221 cgataaactg ggttatgttt tactaactat tgacggatat gagcctgatt ttcaaacacg
    11281 tcaaaaaatc atgtttgttc ctaaatgcca actcactagg atagcgtctt ttctaacaaa
    11341 ggactctgcc gtcacacttg aagatcaata gaaatgatgt cattaccaaa agaatttatt
    11401 aacacttatc aagcaatact aggcaaagaa ttagaagatt tcttggcaag ttttaaccaa
    11461 gagccggtca atgcttttcg gattaacccc ttaaagaatc aactaaaaac ctttgaacac
    11521 cccattccaa ataccttatg gggatattat ggtaaactat ctggcaagtc tccagagcat
    11581 gtgtcggggt tggtttattc ccaagaacca gcggctcaaa tggtggcaca agtagcggct
    11641 cctcaaaagg ggagtcgtgt tttagacttg gcagctgcac caggaggaaa atcaactcat
    11701 ttattagctt atttagacaa tacaggtctt ttagtcagca atgaaatttc taagaagcgc
    11761 agcaaggttt tagttgaaaa tatcgaacgt tttggcgcta gaaatgttgt ggtgactaat
    11821 gaatccgcag atcgtttagc caaggtattt tctcattatt ttgatactat cgtctttgat
    11881 ggaccatgtt ctggtgaagg aatgtttcgc aaggaccctg atgctattca atattggcat
    11941 cacgggtatc ccgcagaatg cgccaagttg caaaaatcta ttttagaaga cgccttaacc
    12001 atgttaaaac caggaggaga attgatatac tccacctgta cttgggctcc tgaagaaaat
    12061 gaagatgttg tgcagtggct cttagagact tatacctttt tagaattggt cgatgttcca
    12121 aaactaaatg gaatggttag tggtatcgga cttccagaga ctgctagaat gtaccctcat
    12181 cgttatcaag gggaagggca atttgtggcc aagctaaaag ataagcgtca agaaggacaa
    12241 agcactaaac taaaagcacc taaatccaac ttgaccaaag accagttacg tctttggaaa
    12301 atgtttgaaa aagaccatct aaaccttacc ctatcaggaa cactacaaac ctttggtgat
    12361 tacctatacc tcttgccaga tggtcttcct gctttagatg gccttaaaat tgctcggaac
    12421 ggtttagaat taggcgtctt caagaagaaa cgctttgaac cctcttacgc cttgggatta
    12481 gctttaaagc ctgatgaggt ccgatcatct attgagctta gagaggaaga ctttagacct
    12541 tatgtgtcag gtaacgtcat tactttgccc caatcttatc caacaggctg gtaccaatta
    12601 ctcattaatg gcaatggtct aggatttgcc aaggtcgttg acaagaccat caaaaataa
//
LOCUS       DAUNLR010000050        12604 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUNLR010000050 DAUNLR010000000
VERSION     DAUNLR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12604
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.050"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(147..3644)
                     /locus_tag="VLL59_001432"
     CDS             complement(147..3644)
                     /locus_tag="VLL59_001432"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HER6509550.1"
                     /translation="MKKKVNQGSKRYQYLLKKRGIGFVIAATGTVMLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGFQSSSKEAKPVLDSSSTNPDSIAEHHLRMHFKT
                     LPADETLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKIPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVVIDELTLDRDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKTRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLESN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAKYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYHYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTGPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRRKD"
     gene            complement(3842..5455)
                     /locus_tag="VLL59_001433"
     CDS             complement(3842..5455)
                     /locus_tag="VLL59_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HER6509551.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDSEITGNGPRLHDYL
                     KKMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVDDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSKAQETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFATDLAGAQ
                     VIIANTDVDTVLETKHLQPWDAFCLKLKA"
     gene            complement(5584..6717)
                     /gene="ugpC"
                     /locus_tag="VLL59_001434"
     CDS             complement(5584..6717)
                     /gene="ugpC"
                     /locus_tag="VLL59_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HER6509552.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(7015..7863)
                     /locus_tag="VLL59_001435"
     CDS             complement(7015..7863)
                     /locus_tag="VLL59_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HER6509553.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            8203..9525
                     /gene="ska"
                     /locus_tag="VLL59_001436"
     CDS             8203..9525
                     /gene="ska"
                     /locus_tag="VLL59_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HER6509554.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSQPAHGGKTEQGLSPKSKPFATNSSAMPHKLEK
                     ADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKAVHNSAKRVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGD
                     SLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYGINKKSGQEEKMNNTDLISEKYYILKKGEKPYNPFDRSHLKLFTINYVDVNTNKLL
                     KSEQLLTASEHNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDDTNRIIT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPKDK"
     gene            complement(9623..10066)
                     /locus_tag="VLL59_001437"
     CDS             complement(9623..10066)
                     /locus_tag="VLL59_001437"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HER6509555.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     RQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(10081..12300)
                     /locus_tag="VLL59_001438"
     CDS             complement(10081..12300)
                     /locus_tag="VLL59_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HER6509556.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKTDVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGHDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLMHLTTVVEKIKAVPDVYSVKRTNG"
BASE COUNT         3549 a         2885 c         2439 g         3731 t
ORIGIN      
        1 ttaaagttct ttttttaagg attttagacc aatcctggtt ttgtctatga caaaaagaaa
       61 ttcgctcgat gcttttgaaa gaaacttaaa gcaggcaata gcaaatagca cctgaaattc
      121 attcaagtgc tattattaac accaccctaa tcttttcggc gcttcatcaa caggctaata
      181 gccaataaaa gcagagctac tccagctgct aataagcctt ttgaggaggc ttcacccgtt
      241 tttgggagct tttggtttgt tttagctctt tttggcccag tcattaatga tttgtctagg
      301 tcttttgagc catctggtgt tttggtttga tgattgtctg tctgactctt ttgctgagag
      361 ggattagccg tttttgagga tactttgagg accagggcag ttaggccatc aatagtcaag
      421 ccttctttgg taaactggac tcccttaggc ttagcaatgg cagtaacacc agcttgctca
      481 gcatcagcaa gcacttgggc tcctagcaaa tagtggtagg cttgaggtaa aactaccttg
      541 cgggtcttgt tgtctgcatt gacaaagaca gcatagcgat ctccatttga tgccaccgtt
      601 tggtaaccca tgataaggtc ctcttgttga ataccatctt gtcctgcttg ggtgatcaag
      661 gtcacatccc gatctacctc agctttggtt gcttttgtaa aggcatctgt tgagcgacgc
      721 aacgcaatta gtccctgtgt ataggctttt gtttggttgc taatcgggtg agctatggaa
      781 tctgttgcct ttgcccagtc aaaatgattg accgcatcag acgaatcata agaatcgtgg
      841 atgaagtaag ggtatttcgc tacagcatca atcagagtcg ccttatttgg caccttgtca
      901 tcagacacct ttgtcttgta gtcgggattt agaagctgct tggttcgtcc atattcctga
      961 ccagaatgga taaaggcagt cccttgagca gttaaaatca tggtatttcc tagacgaata
     1021 cgcttgtgaa tctcttcttc agccacttta ggatccttat tgatggattt ggcaatgaca
     1081 tcatgtaagg tcaggttgtc atgggctgca atatactgca ctacatctcc tggggcatct
     1141 gcttcaaaat tactaggctg tgctttgatc gttttgaata aaccttctag attttttgcg
     1201 ccaccagtaa taaaggctgc tgtgccttca tttggaaaac ctgacttgag ggtatttctg
     1261 atatcatcag agaaaacacc gaccgtattg gttgctttca tccaatcttg atctgccgca
     1321 atttcttttt tcccctcatc accttggtag gtacgccagc cttcgccaat cataatggta
     1381 tttggattaa tggctttggc tgccttaaag gcttgctcaa tagctgccgc atcatggtca
     1441 cccatcatgt cgaaacgaaa accatctacc ttgaattcac gagtcagata agtaatcgaa
     1501 tccaccaaga tacgacgact catggcatgt gtcgttccta gacgacctcc gccaaaactc
     1561 tctctagctg taccatcagc attcataaaa tgatagtagt tggattccaa atcttcaaag
     1621 agataggttc tagccgtgtg gttataaacc acatcaaaaa taacacccat accacgtttg
     1681 tgaatctcat tgacaaggtt tttaagctct gcgatacgta aagcagggtc gttaggattt
     1741 gccgaataca tgccagaaag ggcaaagtag tgttgtgggt cataacccca gttgtaatta
     1801 ttgtctgaag acgtgtaggc tgttgagcgg gtcttgtcca gctcattggc ataaaaataa
     1861 ctcaaaaccg gtagcaattg aacgtgggta acccccaagt ctttgagata gtctagctgt
     1921 tcaacgaaag ctgaaaaagt cccaaaaggg tgtgttaact tgccttctag agccttatct
     1981 gacgtaaaat ctcgcacatg tgcttcatag ataatagcgt cttcacgttt tttaaagttg
     2041 ttaattttgg caaaatcaag gcctgttggt cctagtttgc ttggatcaat aaaggcagct
     2101 tttgctgttt tgatgtcatc agtagcagtc gcatcattcc aggcagcgag agatttggcg
     2161 taaggatcca aaaccatgac tttttcctga ccgcgcgtga tttcataaag gtaatagtag
     2221 cctgtgtaat cactaatgcc cttgacacta tcagaagtca gatgagctct ccaaacaccc
     2281 ttgtccgact tggtcaaatc agcttgacca accacccttg tctgatcttg tttatcataa
     2341 acgacaacct taacagtatc agcacttgga gaccatagcg ctaaatcaac agaaccatcc
     2401 ttagctaggg tagctccaag ttcaccatcg taagcataga gtttatcttt taattgccag
     2461 gattggcgag cgacttggct aacttctcca aatgtaaccg tgtagactgc accttgcgcc
     2521 ttaaaatcac cctttaatgt cattacagac ttatccctgt caagtgtcaa ctcatcaatt
     2581 acaacagttt tccctgcttt gtcagtgatc ttgatgtttt gtttcaccgc atcttcatca
     2641 agcccatcta aggtcgtaaa aatggcttta atctcatttg gcgtggtttg ttcagcacct
     2701 ttgagactaa cctgatcaat ataataagga ttgttgtaaa cttttgggtc agtgtctttg
     2761 acaaaaacct gagtatgatt gtctaactct ttaaatagat aatcttttgg ttgcacttta
     2821 atagcatctc ctgtcttact tttatcaagg attaaaaatc cgatttcgtt agctccttct
     2881 tttaagggga catcaacata agctccataa ggccctttat gtgacaagtc aagtccattt
     2941 ggccagtcgg tcgttgggat tttgacatct ttaaaggtcc agacagctaa gttatcgtag
     3001 tgtcccgatt gattgtggta gttgattcga aggtaacctt ttttcaaagg tcgataagcg
     3061 tgcgcatggt aattctcgtc tatccaaact tcattcattt ttggcgtgag aagcgagatg
     3121 tgctggtcct ttgaaagatt ctctccagct ttattattaa tgagataaga cacttgctgg
     3181 cggtgtttag ctgctagtgg cacatctaga taatagccat agtcatcttt tttcgccttt
     3241 gtcatggtga tagcaccatt tggccaatcc tttgaaggtt gatccacatc tccccacacc
     3301 caaagtccca agcttcctag cgtctcatca gctggcaatg ttttaaaatg catacgcaaa
     3361 tgatgctcag caatactatc aggattagtt gacgagctgt ctaaaactgg ttttgcctcc
     3421 ttgctagacg attgaaaacc atcaccagat ttagcattgc catctccttg ttgagcttca
     3481 tcgcgagcta gtccaacaat ggttttagca gcaacttgat gtgttaagat actaggggtg
     3541 caccctaaca tgacagtccc agttgcagcg attacaaaac ctatcccccg cttttttaac
     3601 agatactgat agcgctttga tccttggttg actttctttt tcataagacc tccatttagt
     3661 ataacattca aacaagacta tcttatcaca ttgcgcaagc gcttgcaaga cgtgccgcac
     3721 ttcaacttag aacacagctc aaacaatgac tatcacccct taataggatc tcaaaaatca
     3781 aacagccaaa acgagtttcc gctcgcttgg ctgttgggta aactcaaatc acatacaact
     3841 gctaggcctt cagtttgaga caaaaggcat cccaaggttg taagtgcttg gtctctaata
     3901 ccgtgtccac atctgtattg gcgatgatca cttgtgcacc tgctaagtct gtggcaaaga
     3961 cttgctcctc atcagacaca ttgacaacaa tcacatacgt ctcttctcca agctgacgct
     4021 gataagcaaa cactttatca gctgttggca agaggtgata atccgcttca actagccagt
     4081 cttgctcctt acgcaaggca atcaattttt ggtaggtgta aaaaatagag tctggatcag
     4141 caagggcatc ggccacattg atgtcttggt agttggggtt gaccggcaac caagtctctt
     4201 gggctttaga aaagccagca tgtgtgtcct tagaccactg catcggcgtt ctagcattgt
     4261 ctcgtcctac cttacggatg ctatccatca cacgcgcagc tgacactcca tttcccatag
     4321 cttccttagc atagttgagt gactcaatat catcaacctc agttaagtct ttaaaaggat
     4381 agttggtcat gccaatctct tctccttggt aaatgtaagg ggttcctcgc atcaaatgca
     4441 gtaaaatagc taaagccttg gctgattttt ctcggtaagt gctgtcattg ccccaaatgg
     4501 ataagacccg tggcaagtca tggttattcc aaaaaagcga attccagcct tctcccaact
     4561 ttaattctgt ctgccacttg ctgaaaatag ctttcagggc aggcacgtct aattctttgg
     4621 cataatccca cttgggagcg tcaggtttat gttgaagacc cacatgctca aattggaaga
     4681 ccatggataa ctctttgttt tcagggcgag aatactggcg agcaatttca ggcgttgctc
     4741 cccaagtctc accgacagtc atcacgtcat ggttgccaaa ggttgcttga ttcatttttt
     4801 tgaggtaatc gtgtaagcgc ggcccgttac ccgtgatttc agaatctgga accttcccaa
     4861 tcaggtcaat cacgtccata cgaaaaccac cgatgccttt ggcaatccag aaattcatca
     4921 tatcgtaaat tttatgacgt aaagcttcat tctcccagtt gagatctggc tgacgtttgc
     4981 taaaaaggtg caaataatat tgacctgatg cattatcata ttcccaagct gagccactaa
     5041 aaatagaagt caaatcgtta ggttcatctc gccaaatata aaaatcacgc tcaggactat
     5101 tagggttttc cctagcttca acaaaccaag catgctcatc agacgtatgg ttgaccacca
     5161 agtccatgat aatcttaatg cctcgctcgt tagctgctgc taagagctca tccatatctg
     5221 ccatgtctcc aaaaacatca gcaatcgctt catagtcaga gatgtcataa ccattgtcat
     5281 ccattggact ttggtaaaca ggagataacc aaatggctgt aatgccaagt ttttgcaagt
     5341 agtccagttg actggtaatg ccttttaaat caccaatacc attgccgctg gtgtctttaa
     5401 aggaccttgg gtaaatctga taaatcgtag ctttatgcca ccagtgtttc ttcattattc
     5461 ttctcctatt aatcattcat tcatctttta ttttaacgtt ttttctcttt ttgtgcaatc
     5521 gtttgcgcaa atgacatgat aaaaaggttg gaacccaacc tttttatgaa tatcgcttat
     5581 accttaacga atagcttgtt cggtatctct gtcaaagaaa tgccctttag ccacattaaa
     5641 ggtcaagcta acttgctccc ctggactatg gaaatcacgc gcatctacac gagaagcaaa
     5701 ctcagtttgt ccaagcttga catagagcat cgtctcagag cccagtaact cagaaaccaa
     5761 aacttctgct gtgacagttg cacttggata agtatcatgc acgatttgtc tgctagaaat
     5821 gtcttctgga cgaataccaa aagtgacttt tttccccttg taaccagccg cttcaagcat
     5881 ttttgcttgt ccttcaggaa tcgcaatagc aagaccatct tcactcacaa tgcggccatc
     5941 tttaacttcc acttcaaaga agttcatggc agggcttccg ataaagccag caacgaattt
     6001 attagctgga aggttgtaca attcttgtgg cgaacccact tgttcaattt taccaatcgt
     6061 tccattaccc tgagggtttt tagtggcact catgataacg atacggtctg ccaaggtcat
     6121 ggcttctgtc tggtcatggg taacgtaaat agttgttgag ccaatcctgc ggtgaatctt
     6181 tgcgatttca gcacgcatgg agacacgaag cttcgcatcc aagtttgaca aaggctcatc
     6241 catcaagaac actttagcat cacggacaat agcacgcccc atggcaacac gctgacgttg
     6301 accaccagac aggtcagccg gtttacgctc taaaaattcg gtcaaaccaa gaatctgcgc
     6361 agcttccttg acacgacggt caatatcatc ttttttgtac ttacgtaatt tcaaaccaaa
     6421 ggccatgtta tcatacacag tcatgtgtgg gtaaagggcg tagttttgaa agaccatggc
     6481 aatatcacgg tctttaggag acttatcatt caccacttcg ccaccgattt ttaactctcc
     6541 ttcagaaatg tcctcaagac ctgcaatcat acgaagagta gtcgatttac cacatcctga
     6601 aggtccaaca aagacgataa attctttatc tttgatgtcc aagtcaaaat cttcaacggc
     6661 ataatgagta gtatttgggt attttttata gatgtgattt aaatttaatt caaccatgtg
     6721 taactcctat ttagccagca aacgttctag ctgactgcaa agctagaaac cgctgatatc
     6781 ttttatatga tgcttttatt ataacaaaaa tagcgctttc aaaacagaga caaagcgacc
     6841 aaacttcttt gggcaacttg cacaatagca gggctagtca agtcgtaagg gaccataaaa
     6901 caagaaaacc atgtaaacac aggccggtca caggagccaa aacaagctga acgatctatc
     6961 attctcctta tcagctacag ttcaggcagc aaaaaagaaa gccctgtggc tttcctaata
     7021 tttcaacaaa aagagatgag caaaggctaa atcatccaat tgcttcaagt gtagtcctga
     7081 ttgctgagca aatttatcaa gtttgtattg caaggagtta cggtgaatat acaagcgctg
     7141 cgctgtctgc accagattgc cgtgttctga ccatagcgcg tgaaccacat cggccatatc
     7201 actttgagga cttaggaatt ggtgaaactg acgcgtcaat gccaaaaaag tgtggtgcga
     7261 cagcaaagac cacagcatca gtcctgaaaa tgttaataat tttctgcctg attgttgcct
     7321 taaataggcc gttaacagct gacattcctc ctcaaaacac tctctcaatg tacccgcagc
     7381 tacttgatac caggcatttc caacaaacat ggttaaggcc aaaccaaaat cactttctag
     7441 cgttggcaag agatcttcaa gccagcgcaa gacctttatt gagattgctt gtcggcataa
     7501 aaatgccgtc tgagttgcac tgataggcaa aatgacctca agccctgcaa tcatctgttg
     7561 gagcaactca actaagtcat ctggtaaagc ctgctgatga ttgaggtaaa tgaactgaga
     7621 agtctcaaac agctgagggg gattgccctg atgatcaagc aaataccgct gccaaggtga
     7681 ccctagcggc tgcaagacct cacactgacc cagccccacc tcaagtaata agcgctcttt
     7741 ttcggataaa catgatttgg gaaaatgcac atattggtcc ccttctttga cactcaccca
     7801 ctctttatct cctaacggat gagggcctac ttgcatctct ggaaaatagt cttttagctc
     7861 catagccatt cctttcatga tggtctttaa accattataa cacatgactc tttatcacac
     7921 agttcggttt gttgtcagca cgattttgta ttttctgtct ttttaatcat taaagctaaa
     7981 taagtgttat tcatttttag caagaacatt caatcaaata gctatttatc ggaagattaa
     8041 tttatgttta tactaaaaca ggtattattt ctcttttttc attatcatga cgttatcatt
     8101 aagatatcat ttaaaaacaa ttattaggtt tttgtttgta tctataaaat tattatgtta
     8161 ttctaataat ggggattgaa acttaacttt taggaggttt ctatgaaaaa ttacttatct
     8221 tttgggatgt ttgcactgct gtttgcatta acatttggaa cagtcaagcc tgtccaagct
     8281 attgctggac ctgaatggct gctagaccgt ccatctgtca acaacagcca attagttgtt
     8341 agcgttgctg gtactgttga ggggacgaat caagaaatta gccttaaatt ttttgaaatt
     8401 gacctaacat cacaacctgc tcatggagga aagacagagc aaggcttaag tccaaaatca
     8461 aaaccatttg ctacaaatag tagcgcaatg ccacataaac ttgaaaaagc tgacttatta
     8521 aaggctattc aagaacaatt gatcgctaac gttcacagta acgacggcta ctttgaggtc
     8581 attgattttg caagcgatgc aaccattact gatcgaaacg gcaaggtcta ctttgctgac
     8641 cgagatgatt cggtaacctt gccgacccaa cctgtccaag aatttttgct aagcgggcat
     8701 gtgcgcgtta gaccgtatca acctaaagcc gttcacaact cagctaaacg cgttaacgtc
     8761 aactatgaag tgagctttgt ctccgaaaca ggaaatttag actttacgcc atcgttaaaa
     8821 gagcaatacc atttgaccac actagcagtt ggtgactctc tttcatcaca agagttagca
     8881 gcaattgccc aatttatcct atcaaaaaaa catccagatt atatcattac aaaacgtgac
     8941 tcctcaatcg tcactcatga caatgacatt ttccgtacga ttttaccaat ggatcaagag
     9001 tttacttacc atatcaaaga ccgggaacaa gcttatggga tcaataaaaa atctggtcag
     9061 gaagaaaaaa tgaacaacac tgaccttatc tctgagaaat attacatcct taaaaaaggg
     9121 gaaaagccgt ataatccctt tgatcgcagt cacttgaaac tgttcaccat caattacgtt
     9181 gatgtcaaca ccaacaaatt gctaaaaagc gagcagctct taacagctag cgaacataac
     9241 ttagacttca gagatttata cgatcctcgt gataaggcta aactactcta caacaatctc
     9301 gatgcttttg gtattatgga ctatacctta actggaaaag tcgaggataa tcacgatgac
     9361 accaaccgta tcataaccgt ttatatgggc aagcgacccg aaggagagaa tgctagctat
     9421 catttagctt atgataaaga tcgttatacc gaagaagaac gagaagttta cagctacctg
     9481 cgttatacag ggacacctat acctgataac cctaaagaca aataaccacg atcttctaaa
     9541 acgatgagat taactgacaa aaaaagcaag caacacgcta tcaacagttg cttgcttttt
     9601 tctaatctct tagttgtaga gactagtgac atttcgtgtc taaaataatc gtaactggtc
     9661 catcattgat gagactaacc tgcatatctg ccccaaaaac gccacgctca actggcacaa
     9721 actctgccaa ttgttcatta aagctatcat acaactgcct agccaaatct ggcttagcag
     9781 caccagtaaa ggcaggacgg tttccctttt tggtgtcagc ataaagggta aattgcgaca
     9841 cagataagat actgcccttg atgtcttgga tagactgatt catcttgcca tcagcatctg
     9901 aaaaaatgcg catgttgact atttttcgca cagcgtaagc caaatcttct gcattatcat
     9961 ctggtcccac acctactaac aacaacaatc cttgattaat agcgccagca attttcccat
    10021 caatagaaac agaggcctct ttgacccgtt gcaagacaag tttcatgttt ttatcctttc
    10081 ttagccattg gtccgcttca cgctataaac atctggaact gccttgattt tttcgacaac
    10141 agtggtcaga tgcatcagat ttggaatgcc aaagctcacg tgaatattag caaacttcat
    10201 gtccttggtc ggctgagcat tgactgtcga tatgctcttg gttgagtttg ataaaatttg
    10261 gagcacatca ttaagcagac cactacgatt gagcccatag atatcaattt cagcctgata
    10321 atctttactc gaattgtcca aatcccactc gacctcaatc aagcgttctt ggtagccatc
    10381 ttgactctta atgttatgac agtccgatct gtgaatcgca atgccacgcc ctttggtaat
    10441 gtagccgtca ataggatcac caggtacagg attacaacac ttggcaatcc gcatcaagag
    10501 gcctgatgct ccttggataa tgaccccatt ttcactgcga accttgagca catctttgtt
    10561 ttcgtgtttg acctcaccgc ccttaaccaa ttcttctgct tctgctttag ccttggccct
    10621 ttcttcttca cggcgctctt tttcggttaa cttgttaaag acactgatag gactaatgtc
    10681 accaaaccca acggctgcat agagcgattc ttcactcttc acactgactt ttggaaggat
    10741 cgcttcaatg cgttttttgt caaggtattt attggcaacg tagccctgct cttgaaaata
    10801 agacaccaac aaatcacggc ctttattcac tgacaattcc ttgtcttgat ttttaaagaa
    10861 ctgacgaatt ttgttgcgag ccttattggt tttgaccagt tttacccagt ctcgactagg
    10921 gccaaaggaa ttggcattgg tgatgatttc aaccacatct cctgttttta acttggcagt
    10981 gagaggaacc atacgtccat tgactttggc acctgttgct ttttcaccga tttgcgtatg
    11041 gatcgcataa gcaaaatcaa taggacctga ttcttttggt aactcctgaa cggcccctgt
    11101 cggtgtaaag acataaatcc gttcagaaaa aatgtcttct ttgaccgaat ccacaaagtc
    11161 cactgcatca ccatttgagg catcttgcaa ttctaccagc tctttgatcc agttcatgcc
    11221 aacggcttgc tcagcctgat tgaccttacc acgcacgcct tttttataag cccagtgagc
    11281 agcaaccccg tactcagcca cttgatgcat gtccttagtt ctgatttgaa tctcaatagg
    11341 tccttttggc ccatacacag tggtatgaat cgactgataa ccattagctt taggagctgc
    11401 aatataatcc ttgaagcggc ctggcatggg acgccaaagc tcgtgaatat agccaaccat
    11461 agcatagaca tcgctttgcg tttccatgac acaacgaatg gcaatcagat caaaaatctg
    11521 atcgaaacgt ttctttttgt cccgcatttt tcgataaatc gaataaatgt gttttggtcg
    11581 gccatacaca tctccaaaca acccttgttg tgtcgtatag gttttgacct tactgacaat
    11641 agcctccacc aaagcttcac gctcacgacg tttttctttc atcatatggg aaattttgta
    11701 aaattcggtt tcattgaggt aacgaaaagc caaatcttct agttcccatt tgatgcgact
    11761 aatccccaaa cgatgcgcca agggagcata gatttccatg gtttcgcgcg aaatgcgctc
    11821 ttgtttgtcc ttgcgcaaat gtttgagggt gcgcatatta tgcaggcggt cagccaattt
    11881 caccaaaatc acgcgaatat ctttggacat agccatcagc attttgcgat ggttttcggc
    11941 gagttgctcc tcatgagatt tgtactcaac tttacctaac ttggtgacac catcaacgat
    12001 atcacgagca tcatggccaa agtctgcttc gatctcatct aaagtaatat ccgtatcttc
    12061 tacgacatca tgtaaaaagc cacaggcaac tgtcacagca tccagatgca aatcagccag
    12121 aatccccgcc acctgaatcg gatggacgat atagggttcg cctgactttc tcacttggta
    12181 gaaatgggcc gctgttgcat atgctaaagc ctttgccaca aaagccacat cagtcttggt
    12241 catataggtg gccgctaagg caatgacttc ttctcctgtt acgttcatta tttttgccat
    12301 ttcgttcctc atctagcatt tcttttccct attttaacac tttacacaca aaagcaaaag
    12361 gcagaatctg ctaagaaagc gcttagtgtg accttttctt agaaaacggt tagtgagctg
    12421 cttttgatat cttttgggat ctctcaggcg tgagcatgat accaaaggcc tgctcccgac
    12481 caaaaataga gagaaccaag gggctctctc tattatgttt gcttatcagt aaggtctctc
    12541 aatttagagg attagttgtt ttctttgcgt tttgtaacgg ctaggacacc agctgttgtc
    12601 atca
//
LOCUS       DAUNLR010000051        12366 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUNLR010000051 DAUNLR010000000
VERSION     DAUNLR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12366
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.051"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            62..1030
                     /locus_tag="VLL59_001439"
     CDS             62..1030
                     /locus_tag="VLL59_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HER6509557.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEIDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            1089..2087
                     /locus_tag="VLL59_001440"
     CDS             1089..2087
                     /locus_tag="VLL59_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HER6509558.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            2272..3681
                     /locus_tag="VLL59_001441"
     CDS             2272..3681
                     /locus_tag="VLL59_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HER6509559.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPTVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKVAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            4008..5771
                     /gene="lpdA"
                     /locus_tag="VLL59_001442"
     CDS             4008..5771
                     /gene="lpdA"
                     /locus_tag="VLL59_001442"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HER6509560.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAI
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(6445..8862)
                     /gene="hylA"
                     /locus_tag="VLL59_001443"
     CDS             complement(6445..8862)
                     /gene="hylA"
                     /locus_tag="VLL59_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HER6509561.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMSQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASTNITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEASSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTFVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            9095..10084
                     /locus_tag="VLL59_001444"
     CDS             9095..10084
                     /locus_tag="VLL59_001444"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HER6509562.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILAKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            complement(10193..10984)
                     /locus_tag="VLL59_001445"
     CDS             complement(10193..10984)
                     /locus_tag="VLL59_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HER6509563.1"
                     /translation="MTYTSLKSPENTDYLYDLNIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGARVTVDIVSLNDAFDQDYYDLVFFGGGQDYEQTIVAKDLPSKKAALADYIAKNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLYDDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKEKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(10984..12327)
                     /locus_tag="VLL59_001446"
     CDS             complement(10984..12327)
                     /locus_tag="VLL59_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HER6509564.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     GRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFVCLHCQFQRPMLDYQLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIMEAIEKQESKHAYILATYTAMLEFRSLLADRHVVEKEMN"
BASE COUNT         3824 a         2221 c         2562 g         3759 t
ORIGIN      
        1 tttgcaaatt gtgaaaaaaa gttttatcat aaaaaggtaa tatgataata tggaggccga
       61 aatggtaaca gtttctaaag aacaacattt ggatatgttc cttaaaatgg aacgtattcg
      121 tgaatttgat tcacgtatta ataaactcgt ccgtcgtgga tttgtacaag ggatgactca
      181 cttctcagtt ggtgaagaag cagccaatgt tggagcggtg gctcacttgt cttacgatga
      241 cattattttt tcaaatcacc gtggacatgg acaatcaatc gctaaagaca tggaccttaa
      301 taaaatgatg gctgagcttg ctggtaaagc aactggtgtt tctaaagggc gtggtggctc
      361 aatgcacttg gctgattttg aaaaaggaaa ctatggtacc aatggtatcg ttggtggtgg
      421 ttacgctctt gcagttggtg ctgccctcac tcaacaatac aaaggaacta acaatatagc
      481 tgttgctttc tcaggtgatg gcgctactaa cgaaggatca ttccacgagt ctgttaatat
      541 ggctgcaaca tggaaacttc ctgttatttt cttcatcatt aacaaccgtt atggaatttc
      601 aatgagcatc aataatgcaa caaatacacc acacttatac acacgtgcag aagcttacgg
      661 aattcctggt ttctactgtg aagatggcaa tgacgtgatg gctgtctatg aaacaatggg
      721 caaagccgtt gaacatgttc gtggtggaaa tggtccagct attgttgagg tagaatcata
      781 ccgttggttt ggtcactcga ctgcagatgc tggtaaatac cgtactaaag aagaagtgga
      841 tgagtggaaa gaaaaagatc caatgatcaa atatcgtact tatctgacaa gcgaaggcat
      901 tgccactgat gacgaattgg atgctattca agcacaagtc aaaaaagaaa ttgacgatgc
      961 ttatgaattt gcacaaaaca gtccagatcc agaactttca gtagccttcg aagacgtttg
     1021 ggttgactaa gatcaccttg tcagtaagaa gcaatcgtat ttgaataata aatggagaaa
     1081 taaaaatgat gtcagaaaca aaattaatgg ctttgcgtga agcagtcaac cttgctatga
     1141 ctgaggaaat gcgcaaggac gaaaacattt tccttatggg agaagacgta ggggtttacg
     1201 gaggagactt cgggacttct gttggaatga ttgaagaatt tggtcctaaa cgtgttaaag
     1261 ataccccaat ttcagaagct gctatctctg gtgcagctat tggtgcagct attacaggac
     1321 tacgtccaat tgtcgacgtt accttcatgg atttccttac catcatgatg gacgctatcg
     1381 tgaataatgg tgctaaaaat aattacatgt tcggtggtgg ccttattacc cctgtaacct
     1441 tccgtgtggc atcaggttct ggtattggtt ccgctgcgca acactcacaa tctcttgaag
     1501 catggttgac tcacattcca ggaatcaaag ttgttgctcc tggtaatgcc aacgatgcta
     1561 aaggcttatt aaaatcagct atccgtgata ataacattgt tcttttcatg gaaccaaaag
     1621 cgctttatgg taaaaaagaa gaagttaacc aagatcctga cttctatatc ccacttggca
     1681 aaggtgacat caaacgtgaa ggaactgatt tgacaattgt gtcatacggt cgtatgttgg
     1741 agcgtgttct tcaagcggct gaagaagttg cagcggatgg tattaacgtt gaagttgttg
     1801 acccacgtac cctcatccca cttgataaag agttgattat tgaatctgtt aagaaaacag
     1861 gtaaattgat gcttgtcaac gatgcctaca agaccggtgg attcattggg gaaattgcaa
     1921 ccatgattac cgaaagtgaa gcctttgatt accttgatca tccaatcgtt cgtcttgcaa
     1981 gtgaagatgt tccagtacct tatgcacgtg tacttgaaca agctatctta ccagacgttg
     2041 agaaaatcaa agctgctatt gtgaaaatgg caaacaaagg caactagaag ataaggcaag
     2101 tagtctgata aaggctatgt ttatcagtaa cgtctcagct aaaaactatt ttgaaagttt
     2161 ttagaagaac tgagttgtct tatcccgtgt cgcggcacct cacctttcgt atgttttcgt
     2221 agcaaggtga ggatgttgat ggcgcttatc aaatcgtgaa aggatgtaga aatggcattt
     2281 gaaattatta tgccaaagct gggcgttgac atgcaagaag gcgagatcat cgagtggaaa
     2341 aaacaagaag gtgataccgt caatgaaggt gatatccttc ttgaaatcat gtcagacaaa
     2401 accaatatgg aacttgaggc agaagactca ggtgtgctat tgaaaattgt ccgtccagct
     2461 ggtgatactg tacctgtaac tgaagttatc ggttacattg gtgcagaggg tgaatcagta
     2521 gatactattg cttcaagtga aaaaacaaca gaaattccag ttcctgcttc agcagatgct
     2581 ggaccaacag ttgctccaaa agaaaatgtg gcaagtccag ctcctcaagt ggcagcgaca
     2641 gctattccgc aaggaaatgg cggaaaagtt cgtgctactc cagctgcacg taaggtagca
     2701 gcagaaatgg gcattgacct tggccaagtt ccaggaacag gaccaaaagg acgtgtccat
     2761 aaagaagacg ttgaaaactt taaaggtgct caaccgaaag cttcaccact tgctcgtaaa
     2821 attgcagcag acaaaggtat tgatttggca accgtatcag gtactggctt taacggtaag
     2881 gtcatgaaag aagacatcat ggctattctt gaagcggcta aaccagctga agcaaaagcc
     2941 ccagcagcta aagaagaaaa agttgttgat cttccagaag gtgtggaaca caagccaatg
     3001 tcagctatgc gtaaggcaat ctctaaaggt atgacaaact cttaccttac tgcccctacc
     3061 tttacgctta actacgatat tgacatgaca gagatgattg cccttcgtaa gaagttaatt
     3121 gacccaatca tggctaaaac aggccttaaa gtcagcttta cagacttgat tggtatggca
     3181 gtggttaaaa ccttgatgaa acctgagcat gagtacatga atgcttccct catcaatgat
     3241 gctaatgata ttgaattgca ccgctttgtg aaccttggta ttgccgtagg tcttgatgat
     3301 ggtcttatcg ttcctgttat ccatggggct gacaagatga gcttgtcaga tttcgtgctt
     3361 gcttcaaaag atgtgattaa aaaagcgcaa actggtaagt tgaaggcagc tgaaatgtct
     3421 ggatcaacct tctctatcac aaacttggga atgtttggta cgaagacatt taacccaatt
     3481 attaaccaac caaactcagc aattcttggt gttggagcaa ctatcccaac tccaacggtt
     3541 gtggatggtg agattgttgc ccgtccaatt atggcgatgt gcctaaccat cgaccaccgt
     3601 ttagttgatg gtatgaacgg tgcaaaattc atggttgatc tcaagaaatt gatggaaaat
     3661 ccatttgaat tgttaatctg atcaatcagt tttaaacaag aaaagcattc aataataaaa
     3721 gggattttgc taagtttaga cttggtgccc ttttctcaaa aatatagaaa ggatgtagaa
     3781 cgaggagctc tcatgcaaat gagtgataag caattgaatc cgagcgaaaa gctcggataa
     3841 aaatggtaag agttggctaa tcttagcgtc gtagacgtct gaactttcct caatttttgt
     3901 ttcggaaagt cctagtcgtc ctgacgtggg tgcgtcaacg aaatcaaaga tttctgactt
     3961 accgcaaaaa ttcaatcgct ttctccttgc tcttggtatc ttaaattatg gctgttgaaa
     4021 ttattatgcc aaaactcggt gttgacatgc aagaaggtga aatcatcgag tggaaaaaac
     4081 aagaaggtga tactgtcaat gaaggcgata ttcttcttga aatcatgtca gataaaacca
     4141 atatggaact tgaggcagaa gactcaggtg ttcttcttaa aattacacgt caagcaggtg
     4201 aaacagtacc tgtaacagaa gttatcggct acatcggtgc tgaaggtgaa tctgttgagg
     4261 tttctagccc agctgcttca gatgtgaatg ttgctcgtac aacagaagat ttagaagctg
     4321 ccggacttga agtgccaaaa gcaccagctc aagctgcttc agctgcacca aaagctgcac
     4381 ttgctgatga tgagtatgac atcatcgttg tcggtggtgg acctgcaggt tattatgcag
     4441 ctattcgtgg tgctcaactt ggtggtaaaa ttgccatcgt tgagaaatct gaatttggtg
     4501 gaacttgctt gaacgtagga tgtattccaa ccaaaactta ccttaaaaat gctgaaatcc
     4561 ttgatggtat caagattgca gcaggacgtg ggattaacct tgcctcaact aactatacca
     4621 ttgacatgga caaaacagtt gactttaaaa acaccgttgt taaaacctta acaggtggtg
     4681 ttcaaggtct tctaaaagct aataaagtca ctatctttaa tgggcttggt caagtcaacc
     4741 ctgacaagac tgtaaccatt gggtcacaaa ccattaaggg tcgcaacgtt atccttgcta
     4801 caggttctaa agtatcacgt atcaatatcc caggtattga ctctaaactt gtcttaacgt
     4861 ctgacgatat ccttgacctt cgtgaaatgc caaaatcact agcagttatg ggcggtggtg
     4921 ttgttggtat cgagcttgga cttgtttggg catcttacgg tgttgatgtt accgttattg
     4981 aaatggctga ccgcattatc ccagctatgg ataaggaagt ctctcttgaa cttcaaaaaa
     5041 tcctttctaa gaaaggcatg aagatcaaaa catctgttgg tgtctctgaa attgttgaag
     5101 caaataacca attgaccttg aagcttaaca atggtgaaga agttgtcgct gaaaaagctc
     5161 ttctttctat cggtcgtgta ccacaaatga acggtctgga aaatcttaac cttgaaatgg
     5221 atcgtaaccg tatcaaagtt aatgactacc aagagacatc aattccaggt atctatgcgc
     5281 caggtgacgt taacggaacg aaaatgcttg ctcacgctgc ttaccgtatg ggtgaagtgg
     5341 ctgcagaaaa tgcgatacat ggcaacacaa ctcgtaaagc taaccttaaa tacactccag
     5401 cagctgttta cacacaccct gaagtggcaa tggttggttt aactgaagaa caagcgcgtg
     5461 aacaatatgg tgatgtgctt attggtaaaa acagctttac cggtaatgga cgcgcgattg
     5521 cttcaaatga agcccatggt tttgtcaaag ttattgctga tgccaaatac cacgaaatct
     5581 taggtgttca tattattggt ccagctgcag ctgagatgat taacgaagca gctactatta
     5641 tggaatctga attaaccgtt gatgaattgt tattatcaat tcatggacac ccaactttct
     5701 ctgaagtgat gtacgaagcc tttgcagatg tgcttggcga agctatccat aacccaccaa
     5761 aacgtaagta aaacgtcttt gtcttattaa ttaatgaaaa atatcatcat ataatagatc
     5821 acaaaaaaga ctagcacaac tatgaactgc accccaaacg ttagataaaa aaatctaacg
     5881 tttggggtgt ttttgtatga cattaagcta tgaagataag ctagacattt agcgctaaaa
     5941 aaaccgagag aactccgttt gaaagaagca tctctgaaaa gaagaagaca aaaaaacatt
     6001 ataaagaatg gacaaagacg agctctgatt agattttctt ttaaggacgg ctaaattgac
     6061 tcgttctacc tactattatc atcgattatt gcaccaataa ccgtatcaaa ataaaacgaa
     6121 aaggacttag tcctctacaa tacagaacta aatcctttac ttaaaataga gtagccaact
     6181 tttggggctc agtgcagttt ccagtttttt gtctttaata acgtttcatt gttaaccctt
     6241 actttccaat aacagctaaa tccttaagtc tttcttacga aagggttttg tgatatggtt
     6301 aaaagaagca actaaagctc cacctaagaa ttctaaagag gagaactgat acccagtatg
     6361 cggtaagcgt cgttgtcttt tgtggggaat tttatgagag ttaagagcat tgtttttagc
     6421 tgcaattcct tgatcagcaa gcttttattg ctgattttgc ttgacaggat gaggaaaact
     6481 ataaaagcct tgatgagaaa gattatgatt tgaaaacatc gttgcttttt tttcatagtg
     6541 aatgacgtgc atctgttgac tatcatgatc gtagacagcg gccagtttgt cattgttttc
     6601 taacaagtcg atatcaagct tgctaatata ggtttcaaat tcttgacgag tcatatttgg
     6661 aagcatcata taggcataac gatcaccatc ttgagtatgg ttttgcatga tagtgataaa
     6721 ggtatttgaa acttctttga tggcttctgg tgatttgtca tcagctttta tgttttgcca
     6781 tttccctgtt tgaagtgcct tacttatgct aagtgttgtt ggcttgaaga agtagtaacc
     6841 aatattttga gcgggatcat cactttcaag gaaaatactt ttagtgtttg taaaatcaac
     6901 tagctgatta ttcaagtcaa cgggttgatt gttaacataa gaacagtaag ggtgcttttg
     6961 attttctttt cgttgttcaa tagttgtata cgccttgtga gatgattggt ttttgatatt
     7021 gctaccaaca aagattattt tgtttcctaa gataaaccac cctttattga gagtgaggct
     7081 tttattccaa ttagtgaagg tcatagcagc tagagcactt gtgttattaa gttttttact
     7141 tgcaacaaaa gcgtcatcag agagactagt catgccaact tgttgatagt tcgttttaat
     7201 attctcagga gttccctcta gtggtttttg ctcagtttct gtggttccag gtaagcggta
     7261 gggatttaca gttgcccaat agttttcact gtagtgtcct aaatcgttat tgtataggta
     7321 aaacattcca tcagaagtaa accagccatg aagattttca ttattcatag cttcataatt
     7381 ttgagttcga ttcgaaaaca ttgataggcc aaaagcaaaa tcgtgtttat tattatatag
     7441 tgccaattta tccatactat tgaaactagc tacgtaacta tcaagttttt ggactggaac
     7501 aaaagtatca cttagtagtt ctttcataag tttgatatcg tgataggttt tcaaattatc
     7561 atagacattg taaaaagcat tcccttgtgt gacgagtgtt tttatacgtg ttttaagtgc
     7621 caaacggtga ggctcttcag acatgtcagc aatacgtaaa atagcacgaa gtgcttcaat
     7681 gccagcaaca tgagattggg cattaaaacg actgatagaa cgccctcgag tcatatccat
     7741 catttctcca cgaacgatga tagggaaaaa agaatggtta atccaatgat agatagtagc
     7801 cattttatcc gcttctatag gagactttgt tttttgaata ataggaatta attgcgataa
     7861 gccatctata agcacattac cgtaagctcc agtgtaagca atgccttttt tataaagtgg
     7921 actttgagcg ttagtaacca cgtgatcaat taaagaaccg tcttggtaaa aaccatttcc
     7981 ttcgtcaact agcgtgaaaa ctttctcaat tgctttgatt gtatcactaa tttcgagatc
     8041 atctttacga agaataccgg aaatgagttt aacacgtccc atatcaatta aatttccgct
     8101 actggcttca aaaggtgaaa aattggcagc gcgaacccta aaacgagtag ggtcaggcac
     8161 aaatttttcg attggagctg tgtatttaag aatttcttct tgagtaaaat aaggatacat
     8221 caaggataag gtattattaa tagcacgagg agttccaatt tcataaaccc accaattttc
     8281 tttgttttct tttccagttg tttgatgatt ttcacgatct agattataag cgtgttcata
     8341 catgaaggcc ataccgtctt ttacaatagc aatagcttta ctatcttgat aatagcatga
     8401 ttcaggatta gtgatctgtt ttgctatttt ttcaatattg cggtaagttt tcgtgatatt
     8461 agtagaagcg gaataatcct ttgcatgttc ccaaaggtaa gttctatttt cgtggtcagg
     8521 cccttgatag cttttaataa tgttttgagc atccttttca gctttattat gaaaagtgac
     8581 catgtcagga ttggttttat cataagcatc gttgcctgcg ataatactgt tccattggtc
     8641 taacaattca gtatagtagt ctttttgttg tggctgtact accttttttt cgctatctgt
     8701 agtagtgagc gtttgcgttt gaaagtaagt attattaggt tctgaatttg aagtcagtgt
     8761 atcggcataa atggcagttc cttggctcat catagcaaag ctaaggaata ggtttgaata
     8821 aagtagtaat tgtttatggt gtgtgcaaaa ataagtattc actgataaat tcctccaata
     8881 taaaaatgag ataataaaag tagattggtt tactaagtaa aaatatacca tgttaaagta
     8941 tttttataaa cccttacata aataatggct gagtttttgt gcactaataa gtgtaggtac
     9001 tgaagatgtc atacagaata ggacacttgt cttttatatt tgttttcatt atactagaga
     9061 ggtagattac atttttgaaa ggattttttc tcctatgaaa tacatcgtta acaaaagtca
     9121 caatcctgcc tttaacatcg ctttggaagc ctatgctttt agagaactag tggaagaaga
     9181 cgaattgttt atcctttgga tcaatgagcc agctattatt attggcaaac atcaaaatac
     9241 cattcaagaa attaataaag aatacattga tgaacatggt attcatgttg tgcgacgttt
     9301 atctggtggt ggtgcggttt atcatgattt gaataacttg aactacacta tcatttcaaa
     9361 taaaacagcg gaaggcgcat ttgatttcaa aaccttctca caacctgtga ttgcgacttt
     9421 agctgatttg ggtgtaacag ccaactttac aggccgtaat gatattgaaa ttgatggtaa
     9481 aaaaatctgc ggtaatgctc aagcttacta caaaggtcgc atgatgcacc atggttgcct
     9541 tttgtttgat gtggatatga ccgttcttgg cgatgctctt aaggtaagta aggataagat
     9601 tgagtctaaa ggagtgaagt ctgttcgtgc ccgtgtgacc aatattttaa atgaattacc
     9661 agaaaaaatt accgttgagg aattttcaga taaaatcttg gccaagatga aagaaacgta
     9721 cccagacatg acagaatatg tcttgtcgga ggatgagttg gctaagattg aacaatctgc
     9781 caaagagcaa tttggtagct gggattggac ctacggcaaa gcgccagaat atacgattga
     9841 acgcaatgtt cgttaccctg caggtaaaat ttcaaccttt gcaaatgttg aaaattctat
     9901 cattaaaaac cttaaaatct atggtgattt ctttggaatc aaagatgtgc aagacattga
     9961 gaacttatta attggttgta aatatgagta ccgtgatgtt tttgaacgtt taaaaacgat
    10021 tgatacgacc cagtacttct cacgcatgac cgttgaagaa gttgctaaag ctattgtttc
    10081 ttagtggttt taatcactta agaagctctg tcagaagaaa aaactataaa actcctaagc
    10141 gaactatcgt gtcctgctta ggagtttttg tttgatgaca tgaaagaaga acttaaactt
    10201 tattaaagga agctttgctt ttaaggtcgg catattcttc agtgatttct tgtttcagta
    10261 tatcatcata gctaggtagt gaaatagctg atccgtactt ttctttgaga gctgttgtta
    10321 cgagacggta agcaaggttc acgttgcgtg ataagatagg accatggaaa taactgccgt
    10381 agacgttttt atagtgaaca ccttcagttt ggtcttcctt attattacca ttgccataaa
    10441 ccactcgtcc aagtggcttc tcatcatcgt ataagaaggt acgaccttga tgattttcaa
    10501 agccataata ggtttcgtta aattcgtcat tatgaatttt aatatctcca ataaagcgat
    10561 tttggtgctg attaagggtg tagtgtccca taattccaag tccatcaatt ttaaccccat
    10621 tagcttggac atagtattgc cccagtaatt ggaagccacc acagatggca agcaccactt
    10681 tattcttagc gatataatcc gctaaagcag cttttttgct aggcaaatcc ttagcaacga
    10741 tggtttgctc atagtcttgt ccaccaccaa aaaaaacaag gtcgtagtaa tcttggtcaa
    10801 aggcatcatt gagggaaaca atatcaacgg taactctagc tccaagtttt tcagcgacat
    10861 acttgagcat caagacattc ccattgtcac cgtaggtatt catcaggttt ccgtagagat
    10921 gagcaatgtt taggtcatag aggtagtcag tgttttctgg agattttagt gaagtgtaag
    10981 tcattagttc atctcctttt caacaacatg gcggtcggct agcaagctac ggaattctaa
    11041 cattgcagta taggttgcta aaatataagc atgtttgctt tcttgttttt caatagcttc
    11101 catgatttgc tcgagctttt cagcttgctt tattttagta tcgtcaaatc ctgtgactct
    11161 aagtcttcta gcaatttcag agtggcggac gccgccagca ttaatttctg taatgggcat
    11221 ttgggtgatg agttcaaaat tagcatccca aatccagctg gtatcaatgc cgtcagcgta
    11281 attagcattt aaaagcacag ataagctaaa tgggtaatca gctagctgaa tcatttcaag
    11341 cgcttgactg gctccaacag gattcttgat aaggataagg gtgcatgatt tatcaccaat
    11401 agtaaaagtt tcttgtcttc caaaaaccgc cttacttttg ttaaagcccg ccttgatttt
    11461 ctcgggagaa acaccgaaaa attcagcaac agaaacggca gcaagcgcat tgtaaatatt
    11521 ataaagacca ccaacattta tcttgtagtt ttgtccatca ataacaaatt cagaactttg
    11581 gtgagtaata gcggtgagtt cagttaattg ataatctaac attggtcttt ggaactgaca
    11641 gtgtaagcaa acaaagtctc ctagattcgc ataagtattg agacgatact gaagaatatg
    11701 ttcgcatttt ggacataaaa tcccttctgt gttgtaatga gctagctgcg gagcatgctt
    11761 agcagtatca aaaccataat actgaactgg attaactatg tccttagaag agaaaatagg
    11821 actatctcca ttggctagaa tagttgcttt tggagcattt cgagcaccat ctacaatcat
    11881 ctgataagta gtataaatct ctccgtagcg gtccatctga tccctaaaaa tattagtata
    11941 aacaaaaaga ctaggtttta agtaagtggt gattctagga agactagctt cgtcaatttc
    12001 taaaacagca atttgccttc cagatttccc ttttttagca gctaaaaaag tagaagtaat
    12061 tccagtaatc atattggcac cacttggatt tgtgattatc tcgccaaatg cctctttcaa
    12121 aataccgaca gtaagagcag ttgttaacgt tttaccatta gtaccagtga cgaccacaat
    12181 atcatagtct ttagacaaat cctttaaaat atctttatca caagctagag ccaatcgacc
    12241 aggataagta gatcctcgcc ctagttttgt taaaatggat tgagcagctt tgccagcaat
    12301 aatgccgagt aatgtcttca ttttcatgct tatattttat cataagttta ttgattttag
    12361 ataggg
//
LOCUS       DAUNLR010000052        11018 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUNLR010000052 DAUNLR010000000
VERSION     DAUNLR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11018
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.052"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(94..1620)
                     /locus_tag="VLL59_001447"
     CDS             complement(94..1620)
                     /locus_tag="VLL59_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HER6509565.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            complement(1613..2341)
                     /locus_tag="VLL59_001448"
     CDS             complement(1613..2341)
                     /locus_tag="VLL59_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509566.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVANLFGGDEHA"
     gene            2761..3450
                     /locus_tag="VLL59_001449"
     CDS             2761..3450
                     /locus_tag="VLL59_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HER6509567.1"
                     /translation="MKNAISILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     ESNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNLQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            complement(3644..4399)
                     /locus_tag="VLL59_001450"
     CDS             complement(3644..4399)
                     /locus_tag="VLL59_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HER6509568.1"
                     /translation="MGNIALVTGASAGFGRAIVEQLIADGIKVIGASRRLEKLKALET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(4526..5521)
                     /gene="pta"
                     /locus_tag="VLL59_001451"
     CDS             complement(4526..5521)
                     /gene="pta"
                     /locus_tag="VLL59_001451"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HER6509569.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            complement(5525..6430)
                     /locus_tag="VLL59_001452"
     CDS             complement(5525..6430)
                     /locus_tag="VLL59_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HER6509570.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            complement(6427..7263)
                     /locus_tag="VLL59_001453"
     CDS             complement(6427..7263)
                     /locus_tag="VLL59_001453"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HER6509571.1"
                     /translation="MTQMNYTGKAKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            complement(7238..7909)
                     /locus_tag="VLL59_001454"
     CDS             complement(7238..7909)
                     /locus_tag="VLL59_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HER6509572.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGIIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            7997..8575
                     /locus_tag="VLL59_001455"
     CDS             7997..8575
                     /locus_tag="VLL59_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HER6509573.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLFQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFVNSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHITFKYAKSKVARCINTLKKFNDK"
     gene            8715..9695
                     /locus_tag="VLL59_001456"
     CDS             8715..9695
                     /locus_tag="VLL59_001456"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HER6509574.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAADVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            9692..10819
                     /locus_tag="VLL59_001457"
     CDS             9692..10819
                     /locus_tag="VLL59_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HER6509575.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            10809..>11018
                     /locus_tag="VLL59_001458"
     CDS             10809..>11018
                     /locus_tag="VLL59_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HER6509576.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFK"
BASE COUNT         3448 a         2273 c         1867 g         3430 t
ORIGIN      
        1 ttaatttaaa tgttcggctt ttgtatttat gaattgttac ttcttgaact taagagacga
       61 aaaaatgcca gtcctatgga ccaacatttc tgtttatttc tggattaagc ctgttttcaa
      121 cagataatct cgagcgacct tattagcatc tgctccttta acggatacct cgtagttcat
      181 gtcctgcatc tctttttcag taatttttcc cgctaattga ttaagaatgc cttttaattc
      241 tggatgtttt gttaataagg aagttttcat caaaggagct ccctgataag gtggaaacaa
      301 ctgtttatca tcttttaaaa ctttcaaatg gtatttcgtg atttcagcat ccgtagagta
      361 agcatctgtt acttggatat ctcctgattg aattgcttga taacgaagag ctggctccat
      421 cgtcgccaca gatagctgta atccatattg agattgcatt cccttatagc catctgctct
      481 gtccttaaat tccagagtaa aaccagcctt taaagtatca gcatgcgctt ttaaatcaga
      541 aatggtttca atctgatatt ccttagccaa tttttctggc atagcaacag catacgtatt
      601 ttggtaagca aatggcttaa gaagggtcag tttatcttgc ttagcaatgc cttttttagc
      661 atcctcatag acctgcttag ggtcattaga caaaggtggt ttgtcgcgta aaagacttga
      721 tgttatggtt cctgtaaatt caggatagat atcaatatct ccagatttaa gggcttcata
      781 taagaagcta gttttcccaa aattagattt caactcaaca cttatatctg attggtcttc
      841 aattaattcc ttatagagat taatcagaat atcgggctct gctcccaatt taccggcaat
      901 aaccactgta tcttttcctt ttgaaaactg actaagcgcc ataggagtat acgatgctag
      961 caatgcaagt aaggtgattc caaaactaat cataatccgt cgcaaggaag ctttctcaag
     1021 gtactgtaac aaactattga aaataatagc tagcagagct gaagaaatag cccctatcag
     1081 aatcaggtta gcattattac gatcgatccc taataagatg aaagagccaa gtccaccagc
     1141 tcctatcaag gaagctaaag tagctgtgcc aataatcatg actgctgacg tccgcacacc
     1201 tgacataatg acaggcatgg caattggaat ctcaaacgtt tttaaccgct cccatttggt
     1261 catcccaaaa gctattcctg cttccacgag acttgggtca ataccattta atcctgtgat
     1321 ggtgttttgt aaaatcggaa aaatcgcata gataactaaa gctgtcactg caggcaacgt
     1381 tccaattccc attaaaggga tgaaaagacc aagcaaagcc agtgagggaa tggtttgaaa
     1441 aacacctgtt acctgtaaca taatgtctga ccaacgtttg ctgcgactga gaagggctgc
     1501 taaaggcaca cctattagca aggcgatcat aagagataaa agggaaattt gcaggtgttc
     1561 ccccagagcc gccagccatt cattaaaacg gttttggaaa gttacaaaca aactaggcat
     1621 gctcatcacc tccaaataaa ttggccacaa aagcattagc agggtgggtc ttaatcattt
     1681 ctgggcgatc cagttgcaca atttctccct catttaaaat agctacgcgg tctcctaatt
     1741 taatggcctc atcaatatca tgtgtcacaa atacaatcgt catgtcaaat tccttgtgaa
     1801 gactcaacat taactcttgc aattgtttac gtgaaatagg atctaaggct gaaaatggtt
     1861 catccatcaa tagaatttta ggatgagaaa tgatagcacg tacaatacca atacgttgct
     1921 gttcacctcc cgataaatca cttgggtaac gatcaagata atctttagca ggtaggccca
     1981 ccttatccaa taattcttca gttttttgtc taatttcttc agctgaccat tgcttcatct
     2041 cagggataat cgcaatattt tcagctactg tgagattggg gaaaagagca atttgctgca
     2101 acacgtatcc aatagatagc ctcatctcac gtaaatctaa ctctttctgt gggacgttat
     2161 tcagtaaaat atctccagag cttggttcaa taaggcagtt aatcattttt aaaagtgtgg
     2221 ttttccccga tccgctggga ccaaccagca caaaaaattc acggtcatta atttgaaagg
     2281 tctgctcttg caaaaccttt gtctgaccaa aagttttaga aacattatta aaacgtatca
     2341 ttatttctcc aattcattgg ttaaagtaac agcataaaag ctgatgagtt cattcaacct
     2401 gtctctctgt cattttttct caaaacgttc tgagtaacta caaggaatca ctgcatgccc
     2461 taccattttt agacaaacgc atctactaat taaagggact cttaggtatc ctcagtaagg
     2521 tagaaactac caattctcaa aaactttttc tctcattatt ttcttgtcgt ttgttgttga
     2581 ccattataaa aagtttccca ctataagtca aataatgaga ctattacccc attatagaaa
     2641 aacaggtcac tgggtcagcc tatctctcca aaattatctt atcaaaaatc ctagacttgc
     2701 ctatgatgat agataagcag attaattgtc ttttctagaa aatacagcta tcatacaatt
     2761 atgaaaaatg ccatttccat tttagcgctc ttaacacctg aaaaccaact tgaagagacg
     2821 tttattagag agctttccca ccacttctca cacctttttg aggtgactat tctcactagc
     2881 aaagccaaca ttgagtcaaa tcaattgtcg actttccaag gaattttcag tttccatgag
     2941 catgacattg acttgcctac actctatttc aaaacttctc aacatggtca gggcttttta
     3001 gtgacagaaa gtgtctttga tcaagcaaca gcagtcttat cgttaagcca atacctcact
     3061 ggattttacc aaaaatttga tggacatttt ttacagtacc ttcctttgca agcaaggtta
     3121 tctgatgcaa atggaaacat catagtcgat aatcatgctt ttaatggaag ttttttgcca
     3181 actactgata aagaaataga agattggatt cttgctgaat tgcgtttatc agataaccct
     3241 tgtaaaacct tcctacttcc ttcgggttca ttggatcata tttacatgca gcattatcaa
     3301 gctcttaaaa atcttcaagg tcagctggtg ggagttttgg ataccgttca agacattaaa
     3361 ccgttattaa accagtattt agaagaaact ggacaagcca ttgttggctg gtccgatgtc
     3421 acatcaggcc cttccatttt agatcactaa acttgatttt aaatagggag ttcagcctaa
     3481 atcatcaacg cacaagaagc aatcatgaac gcttgaagac ctcaaaacct tcttcttgat
     3541 tgcttttttt gatgactaaa tcggtaagtc tcacttataa agaataatcc ataccagtaa
     3601 accatttttc taaagattat tattcttatg gactcatccc ttgctagtca cgactaactg
     3661 gttgcggtcc ataactttgc gacactggca tcagctcaat acgattaaca ttaacatgag
     3721 ggggctgatg aatcacccat gatacagtcg acgcaatatc ttgaggttga atggcatgtg
     3781 ctccttgata aatggccttc acccgtgcct catcaccatt aaagcgaacc tttgaaaatt
     3841 ctgtcccttc acatagaccg ggttcaatat tggtcacacg tatatggcta cctgctaaat
     3901 cagctcgtaa attgagtgag aactgcttaa caaaagcctt gctagcccca taaatattag
     3961 ctcccggata gggaattgtc cctgcggttg accctaaatt aataataata ccatcatctt
     4021 tggagaccat atgtggtaat aattgacgtg tgagataaat caacccaaca atattagtgt
     4081 taatcatcgt catccaattc tcaaaatcgg cttcataagc cttatcaagt cccaatgcca
     4141 agcctgcatt attcactaaa atagtaatat cttgccactg atttggtaga cttgtcaaag
     4201 catcatcaat cgctttggta tctgtgacat ccatctgcaa agggtaaaag ttgtccgacc
     4261 caaagctcgt ttctaaggcc ttgagtttct caagacgacg agaagcacca ataaccttta
     4321 tcccatctgc aattaattgt tcgacaatgg ctctgccaaa accggctgaa gcccctgtta
     4381 ctaaggcaat atttcccata catttcctca ccttcaaaaa aaacgagatg gtctggccaa
     4441 ctcgttttta ataatgtcaa ttagtcttag gataacttct aacacatcac ttagcggtta
     4501 gaatcctata tcaaggggtc ttaagttacc cttggctttc gatagcttgt gctgctgtaa
     4561 taatagctaa tttgtaaata tcttcagcgc ttgagccacg agataaatca ttaacaggtt
     4621 tgttcaatcc ttgtaagatt ggtccaatag catcaaacat tcctaaacgt tgtgcaattt
     4681 tgtaaccaat atttccagat tgtaagtcag ggaaaataaa agtattggct tggccagcaa
     4741 ccgctgaatc tggtgctttg atagctgccg tttcaggaac aaaggctgca tcaaattgca
     4801 actcaccatc aagtgccaaa tcagggttca accctttagc aatttctgtt gcttctctta
     4861 ccttatcaac ttgaggcgct ttaccagaac cttttgttga gaagcttaac atagcaattt
     4921 taggatcaat atcaaagatt ttagctgttt cagctgtgtt aacagcgatt tctgccaatt
     4981 cttgtgctgt tgggtcaata ttgatagcac aatcagcaaa cacgtaacgc tcactcgtat
     5041 tttcgcgatt catcaagaaa acacctgaag ttcttgaaat acctggtttg gttttaatga
     5101 tttgaagggc tggacgaaca gtatcagctg ttgaatgaat agcaccagat accattccat
     5161 ctgctaatcc cattttaacc aacataacac caaagtaatt cacatcacga agcattttat
     5221 cagcatcttc aagcgttgct tttcctttac ggatgtcaac aaaagcttct ttcattttgt
     5281 caaaatccgc atattcattt ggattaatga tagtatagtc ttgatcagcg aaacctaatt
     5341 ttgtcaaaag gttgcgtacc tcttctgact gtccaaggat aatcggttct aagagtcctt
     5401 caaatttcaa acgagcagct gcacggacaa cgcgctcatc attaccttct gggaaaacaa
     5461 tcttcatgtt tttaccaaga attttttctc ttaaaccacc gaataaacta cgaatactca
     5521 ttctttaata acctctatct tttttctgta aacctatgat aacgctatca aagtcatctg
     5581 tcaagtgtat tgcatagcta caatcacttt ctgtaaatgg atctttgaaa ttcaaataat
     5641 gacaatgtaa agcttgcctt gttattccta agtccaaacg acctccgtaa aggtcatccc
     5701 ctaaaagtgg aaaaccaata tgggcaaaat gaactctgat ttgatgggta cgtcctgtat
     5761 gcaatttgat atccactaaa tgcacatttt ctgaatagcg cgccacaacc ttatagctag
     5821 tcttggcata tttgcccata gggtcaactg ccctggtaat aatactatct tttgaacgcc
     5881 caattggagc aataatatct ccttcatctg gcaacgtccc atttccagaa accagagcaa
     5941 aataacgttt ctctattgag cgagtttgga gttgcttgtc caaccttgca tgagcataac
     6001 catgcttagc aaataacatc aagccactcg tatctctgtc taaacgagtc acgatatgca
     6061 cttgttggtc taggtaatga ttgtccacat aatatgcctt gataaagtta gcaatggtat
     6121 tggagtggat ggcacttgga atactggcaa agccaatggg tttattaatc accaaaaaat
     6181 gatcatcctc gtgaacaata tccaaatcaa aagggatggc ttcaagcttt tcaaagggct
     6241 cttcgtttgg aatgtcaatg gtgacaacat ctcccacttg caataaataa atggcatttt
     6301 gttcaatacc attcactaat atattaccgc ccttatattt gattttagcc aatagtcctt
     6361 tagagacatc atgacttttt aaaagggttt ttacttttat tcgtttatct gctacaaatt
     6421 caaatctcat gagtcaatct ctccaataaa ggcatccttg accctttccc aaaagctcgt
     6481 atgactcgga gaggaaacaa aatgaatttt ctcatcgtcg ataaaatact ccaccttcgt
     6541 cacatttttt aactgatagg ttttattatc aatggaaatg gtataaattc ctaatcgttt
     6601 tggcactaac tcaatcttat cttttttggg aataatgatt gatgagccca aggttctaaa
     6661 gacacggtta ttaagactgg aaatttccgt caattgcagc gcttcaatcg tcggatgcaa
     6721 gacagcacca cctaaagatt tattgtaggc tgtgctccct gtcggggtcg atactgaaat
     6781 cccatcacct cggaagcttt caaatttgac atggttaata ataacatctg ctaccatcgt
     6841 tttttcaata cgcttaaccg tcgcttcatt caaagcacgc gctttaacca cacgaccatc
     6901 atctaaagta atagcaactt ttaaaatagg ataagagatt tgttctccct tgtcttttct
     6961 taaattatca atcaatttat caacttcaaa atccctataa tcggtataaa agccaagatg
     7021 accggtgtgg attcctacaa aacgtacctt atctaattct ttttcataca tgtgaaaagc
     7081 agataagagc atcccatctc cgccaataga aatcacaata tccggatttt tctttgaaag
     7141 atagaaatca ggatcatctt taaatacgga gaaaagtttg gaggcaacgc gtttactttg
     7201 gtacttacca tttgcaataa tagcaactcg ctttgcctta cctgtataat tcatctgtgt
     7261 catcactatt tcctacacca tcacttaaat ttcgtgtcac ggggtcaaac aataattgag
     7321 cctctcgaat atcttctcga atcttacgca tttcttcgtc taattctaaa gcaattttag
     7381 cagtcacttc aagacgcttt ttaatttctt ctgggaagtc tccaccatat ttataattta
     7441 aagaatgctc aatggtcgcc caaaagttca ttgccaaagt acggatctga atctccgcta
     7501 agaccttttt ttgaccttca atggtatcaa cagggtactc aaccaccaca tgataagacc
     7561 tgtagccact ggacttcata ttgcgaatat aatctcgttc ataaacaatt gtcatgtctt
     7621 gtcgttgacg caatagagct aagacttctt ccacatcatc aacaaactga accataatac
     7681 gtagtccagc aatatcttga atatcttgtg ctatattttc ttcaataata ccacgtaaaa
     7741 tcattttttc tttaatactt tcaattgact taacacgtcc cgtaacaaat tcaatcggag
     7801 aataacgatt ttgcttacga tattgcttgc gaataccccg tagttttatt tttaattcac
     7861 caactgtttg gatataagga tctaaaaatt cttcccaatc taaggtcatc tattgtctcc
     7921 tttcttgtca aagccaggat aataatataa aattgaaata acaatttatt atagcacaaa
     7981 ttaaaaggaa tttcccatga ctaacctaga aatcgaatat aaaactctac ttacaaaaaa
     8041 tgagtataac cgtcttttat ttcaaatgaa acatgtgacg cctgttacac aaactaatta
     8101 ctatattgat acaaaagcat ttgatttaaa agctaacaaa atgtcattac gtattcgaac
     8161 atttgtaaat agcgccgaat taaccttaaa agtgccagaa aaagtgggga atcgtgagta
     8221 caatgtccct ctttttcttg aacaagcaaa agatatgatt aaacatggga atcttcctga
     8281 atcaactgct cttgatatta ttatttcaaa aggtatcaaa ccatctgcac tggtaacttt
     8341 tggcaattta actaccgttc gtcgcgagac agtgataccg ataggtaaat tggccttaga
     8401 ctataaccta tatgccaata ccaaagatta tgaattagaa ttagaagtaa gtgacgctct
     8461 tcaaggaaag attgattttg attctttttt atctgaacat cacattactt tcaaatatgc
     8521 taaaagcaaa gtagctcggt gtattaatac cttaaaaaag ttcaacgata aataatggct
     8581 aaaagcgaca gaaaaactga aatttttctg tttttctgtt aaaataggga tgtcaattaa
     8641 acacttttgg gtaatgtgac tcattaataa aacagtttac ccaattttat tgaagttaag
     8701 gagctaaatc tatcatgact gaacgatatg ctgacaagca aatcaaactg ttctcactca
     8761 catcaaatct tccaattgct gaaaaaattg ctaaagctgc tggaatccct cttggaaaaa
     8821 tgtcttcacg tcaattttcc gatggagaaa ttatgatcaa tattgaagaa acagtgcgtg
     8881 gagatgatat ctatattatt caatccacta gttttcctgt caatgataat ctttgggaat
     8941 tactcatcat gattgatgct tgtaaacgtg caagtgctaa taccgtcaat attgtattgc
     9001 catactttgg ttactctcgt caagaccgtg tcgctaagcc ccgcgaaccg attactgcta
     9061 aactagtagc taatatgctg actaaagctg gtattgatcg tgtagtgacg cttgacttac
     9121 atgctgttca ggtacaaggt ttttttgata ttccagtgga taacctcttc acagtccctc
     9181 tttttgcaga acgttacagt aaattaggct tatcaggttc tgatgttgtt gtcgttagcc
     9241 ctaaaaattc tggaattaaa cgtgctagaa gcttggctga atatcttgat tccccgattg
     9301 ctattatcga ctatgcacaa gatgattctg aacgtgaaca aggttatatt attggtgatg
     9361 tttctggtaa aaaagccatt ttaattgatg atattttaaa tactgggaaa acctttgcag
     9421 aagctgctaa aattcttgaa cgctcaggcg ctactgatac ttatgcggtc gctagccatg
     9481 gcttatttgc tggtggagct gctgatgtat tagaaacagc tccaatcaaa gaaattatcg
     9541 ttacagattc tgttaaaact aaaaatcgtg tgccagaaaa cgttacttat cttagcgcca
     9601 gtgatttaat cgcagaagct attattcgta tccatgaaag aagaccctta agtccacttt
     9661 tttcttatca acctaaaggc aaaaataacg catgacttac tttgataacg ccgccaccac
     9721 accacttagt cctaatgtga ttagggcgat gacagcagct atgcaagata actttggtaa
     9781 cccctctagt attcatttct acgggcgccg agccaataaa atccttcgtg aatgccgaca
     9841 agctattgct agaaacttgg gggcaagtga acagcaaatt atagtaacgt ccggtggaac
     9901 tgaaagcaat aatatggcca taaaaggcta tgctttagct catcaagcaa agggcaaaca
     9961 tctcatcaca actactattg agcaccactc tgtgcttcat accatggcct atctcgaaga
    10021 gcgatttggt tttgaggtca cttatttgcc ttgtcaaaat ggacaaataa atttatctga
    10081 cttaaaacaa gccttgagag atgacaccat tttggtaagc ataatgtatg ccaataacga
    10141 aacaggtgac ctgttaccta ttaaggacat tgggaatctg ctcaaagacc atcaagctgc
    10201 ttttcatgtt gatgccgttc aagctgttgg caaactcaag attattccta gcgaacttgg
    10261 gattgacttt ttatctgctt ctgctcacaa atttcatggt cctaaaggat gcggcttttt
    10321 atacagtaac ggacaaccaa tcgaccctct tcttcacggg ggtgatcaag aaggaaagcg
    10381 acgcgcaagt actgaaaata tgttaggtat tattggtatg gcacaagctt tgactgatgc
    10441 tatgacttgt cttgaccaat caactgatca cattatcagt ttacgtcatc acttgattag
    10501 cctcctagaa ggactaccct actatattaa tcaaggtact cattatcttc ctcatgttct
    10561 caatattgga tttttaggct accaaaatac tattttacta acacaacttg acttagcagg
    10621 cattgcagta tcaactggtt ctgcttgtac tgctggagct gttaatccaa gtcatgtttt
    10681 agctgcgtac tatggagatg actcttctcg tttaaaagaa tcaattcgta tcagtttttc
    10741 agatcaaaat agcattgaag atgttaatca attagctcaa acattaaaaa atattttagg
    10801 aggaacagat ggcttttgaa aaagaaatta agcttaaaga ctgtaaatac ctttatacaa
    10861 tcagtccaaa cattaaaaaa tataccctaa gagatactac atttagtcaa actaaagtag
    10921 ggcactacca attaatacgt ttactcgaaa aaatacctaa ttcaggggat ggtttccctt
    10981 taaaaatcac tattaataaa gaactcacag gttttaaa
//
LOCUS       DAUNLR010000053        10742 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUNLR010000053 DAUNLR010000000
VERSION     DAUNLR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10742
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.053"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(190..567)
                     /locus_tag="VLL59_001459"
     CDS             complement(190..567)
                     /locus_tag="VLL59_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HER6509577.1"
                     /translation="MVKINEILSQYNIKLFEFPEAMWDRKGFYYPDKRIIYINQNLSQ
                     IEKEKVILHELGHLEHDPKQYQRLLLKYENQADRFMIRELIKNYLSSHDVVDFNWLQF
                     ATTYQISTTWGQEIIQDEFKKLI"
     gene            complement(551..910)
                     /locus_tag="VLL59_001460"
     CDS             complement(551..910)
                     /locus_tag="VLL59_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509578.1"
                     /translation="MRTNDEIIDLMDNIRKEKNLSISELSRKVGMSKSGVSLYFNKAR
                     KFPLDRANLFAKALGTTPEHIIGVTPKNSPTQTIDLSNLRERVVMFDGKPLSDTDVEK
                     IEAIIKLSLGVGNGEDK"
     gene            1098..1316
                     /locus_tag="VLL59_001461"
     CDS             1098..1316
                     /locus_tag="VLL59_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509579.1"
                     /translation="MAVDYLRVKAERIAKGYTQDYMAKQLGWSDRARYAKRENGFVSF
                     DADELAKVAEILGISKDDIGIFFTYNVH"
     gene            1414..1644
                     /locus_tag="VLL59_001462"
     CDS             1414..1644
                     /locus_tag="VLL59_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509580.1"
                     /translation="MLAKLKSGIEVPYEELWMDDNDLAEFIGKSFDQTQRLLRKMYKD
                     RNYRKYIDKVGGRSTKVKKFEEWRKTQNEKLI"
     gene            1628..1771
                     /locus_tag="VLL59_001463"
     CDS             1628..1771
                     /locus_tag="VLL59_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509581.1"
                     /translation="MKSLFNFIFAKPRKQEEKPKWTIETHGWEAGARRYNQLHGSPGK
                     QVW"
     gene            1781..1999
                     /locus_tag="VLL59_001464"
     CDS             1781..1999
                     /locus_tag="VLL59_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509582.1"
                     /translation="MEQHLINDNEFLRDENRRLNNELAEHYFVVTAKANLLDVIIASG
                     FILQSTIDKCIAELDEIDQMELRKVWNK"
     gene            2001..2243
                     /locus_tag="VLL59_001465"
     CDS             2001..2243
                     /locus_tag="VLL59_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509583.1"
                     /translation="MRLAKQKIGAQQNGYGRIGCDIEIYNEIAEIADKCGYTLTSLTN
                     ALLGYALENSELTAETKTVEVFKFTIGNEDFDNGNN"
     gene            2227..3546
                     /locus_tag="VLL59_001466"
     CDS             2227..3546
                     /locus_tag="VLL59_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HER6509584.1"
                     /translation="MMVTINKLEIENVKRIKAVKIEPSATGLTIVGGNNNQGKTSVLD
                     AIAWALGGNKYKPSQATREGSMVPPTLKITMSNGLIVERKGKNASLKVIDPNGQKGGQ
                     QLLDSFVEELAINLPKFMDGTPKEKADVLLEIIGVGDQLAELELKEKEIYNQRHAIGV
                     IADQKEKFAKEMTYYPDAPKQLVSISELIQQQQAILAKNGENARKRQNVERIRYDYDQ
                     SILEVDRLRKLLADAEAKTNKLSEDLKIANTDAMDLHDESTAEIEANIADIDEVNRKV
                     RANFDKDKAEEDAKQQRDQYNTLTNEIEVIRQQKRDLLTNADLPLEGLTVDDGKLLYL
                     GQEWDNMSGSQQLMVATAIVRKLKPECDFVLIDKLEQMDNITLTQFGQWLEQEGLQAI
                     ATRVSTGEECAIIIEDGYSVENKAHNFETAAAGSFAETVAPAWQGGF"
     gene            3561..4643
                     /locus_tag="VLL59_001467"
     CDS             3561..4643
                     /locus_tag="VLL59_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HER6509585.1"
                     /translation="MQITRGKRARAQRVVIYGPEGIGKSSFAAQFPEPLFIDTEGSTD
                     NMDVARMDKPTSYTMLKNQIAWIKANPTCCKTLVLDTIDWAESLIVDDVCAQHGKKGI
                     EDFGWGNGYTYTKEEVGRFLNSLQELIEFGINVVLTAHAQMRKFEQPDEMGAYDRWEL
                     KLGKKTSSQTAPLVKEWADMVLFANYKTVVMTTDTNKKKATGGSRVLYTQHHPAWDAK
                     NRHGLPEEMPLDYAGIAHIFAQQAPSQPVAETPSTQQPTPTQSAHEPAHKQPTQPPVA
                     NESQAPLPDTLPQAMKDLMVPDQVTADELVQVANIRGHFPLGTPIENFPPNYWDMIVA
                     NWSATLEVIKTQVRVEPDLPFTVEGT"
     gene            4682..5104
                     /locus_tag="VLL59_001468"
     CDS             4682..5104
                     /locus_tag="VLL59_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509586.1"
                     /translation="MDKTIKLDLSAIGEGGLQEKVDKELEKVFDNILDPNTDIKTKRK
                     LTITLTMVPDETREVVSTSMEVKSSLAPQTGVATTVLVGQKDGKVYANELKSKIPGQT
                     YFDEEATLRTDIGQPIDDLERGINEDVIDFNKQKKVGN"
     gene            5106..5840
                     /locus_tag="VLL59_001469"
     CDS             5106..5840
                     /locus_tag="VLL59_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509587.1"
                     /translation="MSENIKEALEYAANTAHEKPKTIIGNDGKEYYDRNKYSLVELKT
                     KYYPKTLNLNTLDSLIDYLKSDMNNINSKRLMVIVEGPREVIVCEEDDDELNRNVLVT
                     VEAIIPNVQFGRYDSPSDFNISLQSLFVNADDRNTVIEFASALKIENGSEIVDDGIGQ
                     TATIKQGVASLAKAKAPNPVTLRPYRTFSEVEQPSSEFIFRINQLANMALFEADGGKW
                     RLDAINNIANYLKEELADQTNITILA"
     gene            5862..6455
                     /locus_tag="VLL59_001470"
     CDS             5862..6455
                     /locus_tag="VLL59_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509588.1"
                     /translation="MTEYNNNFDHELGWDDEITQDSVGFVQLVPGDYQFTVTNMERAR
                     HTPDPQNPGKLPACNKAVVTIQIETSEGIAQLTHNLFLYTTTEGMLSAFFGAIGQKKH
                     GEPLKMNWNTVVGAKGVCRVNKRKGTGKYADQEYDNIKSMIYADEVDWSKVLNASQPT
                     QNTYQQPQQPTQQQPQPQQGSFFQGNTTQPQGGWGGF"
     gene            6455..8038
                     /locus_tag="VLL59_001471"
     CDS             6455..8038
                     /locus_tag="VLL59_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HER6509589.1"
                     /translation="MQLRPYQEEARSAVQKEWEEGRKRTLLVLPTGCGKTIVFSKIIE
                     DRVRLGERVLVLAHRSELLEQASDKLMTATGLGTALEKAENTSLGSWFRVVVGSVQTM
                     QREKRLSKFPANHFDTIIIDEAHHAISDGYQRVLQHFDSSNVLGVTATPDRGDKQNLG
                     KYFDSLAYEYSLVDAIKSGYLSKITAVTIPLSLDLTTVSQQAGDFKASDIGTALDPYL
                     EQIADEMVKQCANRKTVVFLPLVKTSQKFRDILNQKGFKAAEVNGESKDRAEVLEDFD
                     NDKYNVLCNSMLLTEGWDCPTVDCVVVLRPTKVRALYSQMVGRGTRLAPGKENLLLLD
                     FLWHTERHELCRPAHLIASSPEVAQKMVENMTEETEVAFELIEAEEVAAKDVVAEREE
                     ALAKQLAEMRKRKRALVDPLQFEMSIQAEDLADYVPAFGWEQSPPSDKQLEALEKFGI
                     YTDDIGNAGKATKLLERLVKRRETGLTTPKQIRTLERYGFKNVGMWKFEVASNMINRI
                     AASGWRLPKGINAREYQPE"
     gene            8051..8245
                     /locus_tag="VLL59_001472"
     CDS             8051..8245
                     /locus_tag="VLL59_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509590.1"
                     /translation="MENMNEQIEKFINDFVNEAIEKSDTYADAILYVNKIASLTELGQ
                     VIKKAIQDKIGECALNSKIN"
     gene            8268..10511
                     /locus_tag="VLL59_001473"
     CDS             8268..10511
                     /locus_tag="VLL59_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HER6509591.1"
                     /translation="MAENDFNLLPLLDYINPATVDYQTWVQVGMALKHEGYTAMDWDV
                     WSQSDSRYKKGECFAKWDSFQGNGLGTVTGATITQLAKDNGWVSEYRTSDEAHELGWD
                     DTIDRDYKIVDKNWVEAKEIKEPTNWSPVHDLITYIDTLFESTDKVGYVTKTYPIETD
                     EGVVYKPTKGDYARTAGELIQELQKYGNDIGAVLGDYKEEAGAWIRFNPLDGNGVKND
                     NVTDFRYALVESDSMELGKQYALFKELELPIATLVHSGKKSLHAIVKVDARDYQEYRK
                     RVDYIYQICKKNGLDIDTQNRNPSRLSRMPGIMRNGHKQFLIDTNIGKTNYEEWYQWI
                     EDLNDDLPEPETLADEWDNLPELAPELIKGVLRQGHKMLIAGPSKAGKSFALIELSIA
                     LAEGQKWLGWQCEQGKVLYVNLELDRPSALHRFKDVYDAMGLPPTNVANIDIWNLRGK
                     TVPMDKLAPKLIRRSLKKNYQAVIIDPIYKVLTGDENSADQMAHFTNQFDKVATELGC
                     SVIYCHHHSKGSQGGKKSMDRASGSGVFARDPDALIDLVELELTDELIKQRVEKASAK
                     VYQKALQEQNLSYYQHEVTLDDLESRYQMQQHFDKAIPDIMLKQPYLNEIKRITHAIE
                     ISTGWRVEGTLREFAKFQPVNMWFSYPVHEVDTTGVLADIQLEESKPNWQKAKEGRKS
                     KKEKAEERKQKIDTAYSALFDGFTPVSLSELQEYLDSTEKTVRNHLKEHGGFDIKNGI
                     VYQKKTE"
BASE COUNT         3686 a         1906 c         2266 g         2884 t
ORIGIN      
        1 actttgtcaa tcttagatat tagagtgtca aagtattctt tttcgctcat atctccagat
       61 actttactag tatccgatga tagagttttt gatgttgtat ctttttttga gccaccagag
      121 caagctccga gacatactat taagactgat aaggtaaaca aatatactat ttttttcaca
      181 ataaatcccc tagattaatt ttttgaattc gtcttgtatt atctcttgcc cccacgtcgt
      241 tgatatttga tatgtcgtgg caaactgcaa ccaattaaaa tcaacaacat catgagatga
      301 caagtaattc tttatcaatt ccctaatcat aaatctatcg gcttggtttt cgtattttag
      361 tagcaatctt tgatactgtt tagggtcatg ttcaagatga cctaactcgt gtaaaataac
      421 tttttctttt tctatttgtg atagattttg attaatgtag attatccgct tgtctggata
      481 gtaaaaccct tttctgtccc acatcgcttc agggaactcg aataacttga tattgtactg
      541 actaagtatc tcatttatct tcaccattcc ccactcctaa agacaattta ataatagctt
      601 cgattttttc tacgtctgta tcagataaag gttttccgtc aaacatcaca acacgttcac
      661 ggagattgga taggtcaata gtttgtgtcg gagagttttt aggtgtcacc ccaatgatat
      721 gttctggtgt cgtccctaaa gccttcgcaa ataagttggc tctatctagc ggaaattttc
      781 ttgctttatt aaagtataat gatacacctg attttgacat gccgactttt ctagataatt
      841 cacttatcga gagatttttc tcttttctga tattatccat caagtcaatt atttcatcgt
      901 ttgttcgcat tttttcgcct ttcttttatt gactatctaa attataccac cgttctcaaa
      961 aaagcacaat cgttctcacg gaaaaacttt tttatttttt ttagataaaa gtgttgacaa
     1021 taaagaacga tattgatata cttaggttgt tcttttaaga gaacgaaata aaaagacaaa
     1081 acagaagagg gggaaatatg gcagtagatt atttacgtgt taaagcggag cgtatcgcca
     1141 aaggctacac acaagactac atggctaagc aactaggatg gtctgaccga gctagatacg
     1201 caaaacgcga gaacggattc gtatcttttg atgctgatga gttagcaaaa gtagctgaaa
     1261 ttttaggcat ttcaaaagat gatattggaa ttttttttac atacaacgtt cactaaaaag
     1321 aacgatttgt tggttttagc cgcaaaaaaa acgactgcgg gaacagtcgc taactaaatt
     1381 aatttactta attataccat gaaaggaaac aatatgctag cgaaattaaa aagcggtatt
     1441 gaagtacctt acgaagaatt atggatggat gataatgatt tagctgaatt tattggaaag
     1501 tcatttgatc aaacgcagcg attactaaga aagatgtaca aagacagaaa ttaccgtaag
     1561 tacattgaca aggttggtgg tcgttcgaca aaagttaaaa aatttgaaga atggagaaaa
     1621 acacaaaatg aaaagcttat ttaactttat tttcgcaaaa ccgagaaaac aagaagaaaa
     1681 accaaaatgg acaattgaga cacacggctg ggaagctggt gcacgtagat ataaccagtt
     1741 gcatggctca cctggtaagc aggtttggta ggagggaaga atggaacaac acctaattaa
     1801 tgataacgaa tttttgcgag acgaaaatcg caggttaaat aatgaattgg cggaacatta
     1861 ttttgtagtt acagctaaag ccaatttatt agatgtcatt attgccagtg gttttatctt
     1921 gcaaagtacg atagataaat gtatagccga attggatgaa attgatcaaa tggaacttag
     1981 aaaggtatgg aataaatagt atgagattag caaagcaaaa aattggagct caacaaaatg
     2041 gatatggccg cattggatgt gatattgaaa tttataatga aattgctgaa attgcagata
     2101 aatgtggata taccctgacg agcttaacaa atgctctttt aggttatgct ttagagaata
     2161 gcgagctcac agcagaaaca aaaacagttg aagtttttaa atttactata ggaaacgagg
     2221 atttcgataa tggtaacaat taataaattg gaaattgaaa acgttaagcg tattaaagcg
     2281 gtaaagattg agccgtcggc aactggcttg actattgttg gtggaaacaa taaccaaggg
     2341 aaaacaagcg ttctagacgc aattgcttgg gcactaggcg gcaataaata caaacctagc
     2401 caagcaacgc gagaagggtc tatggtgccg cctacgctta aaatcaccat gtctaatgga
     2461 cttattgttg aacggaaagg taaaaacgcc agccttaaag tcattgatcc aaacggtcaa
     2521 aaaggcggac aacaactact agatagcttt gttgaagagt tagctattaa cttgccaaag
     2581 tttatggatg gaacaccaaa agagaaagca gatgtcttgc ttgaaattat tggtgtcggt
     2641 gatcaattag ctgaattaga acttaaagaa aaagaaatct ataatcagcg tcatgccatt
     2701 ggtgttatag cagaccaaaa agaaaaattt gccaaggaaa tgacttatta tcctgatgca
     2761 ccaaagcagc ttgtatctat atcagaactt atccaacaac aacaagctat cttagcaaag
     2821 aatggggaaa atgcccgtaa gcgtcaaaat gttgagcgta ttcgctatga ttatgaccag
     2881 tctattttag aggttgatcg tttacgcaaa ttattagcag atgccgaagc taagacaaat
     2941 aaattgagtg aagatttaaa aatagcaaat actgacgcta tggatttaca tgatgaatca
     3001 acagcagaaa tcgaggcaaa tatcgccgat atcgacgaag tcaaccgtaa agttcgcgct
     3061 aactttgata aagataaggc agaggaagac gctaagcagc aacgtgatca gtacaacaca
     3121 ttgactaatg agattgaggt tattcgccag cagaaacgag atttattgac taatgcagac
     3181 ttgccacttg aggggcttac cgttgatgat ggcaaactgc tgtatcttgg ccaggagtgg
     3241 gacaacatgt caggaagtca acaacttatg gtagccactg ccattgtacg aaaacttaaa
     3301 ccagagtgtg acttcgtttt gattgataaa ctcgaacaaa tggataacat cacacttaca
     3361 cagtttggcc aatggctaga gcaagaagga ttgcaagcta tcgcaaccag agtttcaacc
     3421 ggtgaagagt gcgcgataat tatcgaggac ggctactccg tggaaaataa ggctcataat
     3481 tttgaaactg cagcagcagg tagttttgcc gaaacagtag cacccgcttg gcaaggtgga
     3541 ttttagaaag gagaatatca atgcaaatca caagaggaaa acgtgcacgg gctcaacgtg
     3601 tggtcatcta tggtcctgaa gggattggta agtctagctt tgctgctcaa ttcccagagc
     3661 ctctgtttat tgacactgag ggatcaacag acaatatgga tgtggcccgt atggataaac
     3721 caacaagcta cactatgcta aaaaatcaaa ttgcatggat taaagcgaat ccaacttgtt
     3781 gcaagacact tgtccttgac acaattgact gggcagaaag cctaatcgtt gatgatgtgt
     3841 gtgctcaaca cggtaaaaag ggaattgaag attttggctg gggtaatggt tatacctaca
     3901 ccaaagaaga ggttggacgc ttcctaaaca gtctgcaaga actgattgaa tttggtatca
     3961 atgtcgtcct tactgcccat gcccaaatgc gtaaatttga acaacctgac gagatgggag
     4021 cttatgaccg ttgggaattg aaacttggta aaaagacaag ctcacagact gctccgctcg
     4081 tcaaggaatg ggctgatatg gtactctttg ctaattataa aactgttgtt atgacaactg
     4141 atactaacaa aaaaaaggct actggcgggt ctcgtgtttt gtacacgcaa caccacccgg
     4201 cgtgggatgc taagaaccgt cacgggttac cagaagaaat gccactcgat tatgctggta
     4261 ttgctcatat ctttgctcag caagcaccaa gtcagccagt agcagaaacg ccatcaacac
     4321 aacaaccgac gcctactcaa tccgcacacg aacccgcaca taagcaaccg acacaaccgc
     4381 cggtagcaaa tgaatcgcag gcaccactgc ccgacacatt accacaagct atgaaagatt
     4441 tgatggtacc tgatcaagtt acagcggatg aactagtaca agtggctaac atacgcggac
     4501 atttcccgct tgggacgccg attgaaaact tcccccccaa ttattgggat atgattgttg
     4561 caaattggtc agcaactctt gaagttatca aaacacaagt aagagtcgaa ccagacttac
     4621 cctttaccgt ggaagggact tagattttgg gaaatagaaa taatagcgag gtataacaaa
     4681 aatggataaa acaatcaaat tagatttatc agctattgga gaaggaggct tacaagaaaa
     4741 agtggataag gaacttgaaa aagtttttga caatatccta gatccaaata ctgatattaa
     4801 aacaaaacga aaattgacca tcacactaac aatggttcca gatgaaacac gagaggttgt
     4861 tagtacatca atggaagtta agtcatcctt agcgccacaa acaggtgtag ccaccactgt
     4921 gcttgtcggt caaaaagatg gcaaagtgta tgctaacgaa cttaaaagta aaatccctgg
     4981 tcaaacatat tttgacgaag aagcaacatt acgaacagat atagggcagc cgattgatga
     5041 ccttgaaaga ggtattaacg aagatgttat tgattttaat aaacaaaaga aagtaggtaa
     5101 ctaatatgtc agaaaatatt aaagaagctt tggaatatgc agcaaataca gctcacgaaa
     5161 aacctaagac tataattggc aatgacggca aagagtatta tgatcgcaac aaatattctt
     5221 tggttgaact taaaactaag tattatccaa aaacattgaa tttaaacacg cttgacagtt
     5281 taattgatta tcttaaatca gatatgaaca atattaattc caagcgtctt atggtcattg
     5341 tagaaggccc tcgtgaagtt attgtttgcg aagaagacga tgatgaactt aatcgaaatg
     5401 tgttagtaac tgtggaggca attattccaa atgttcaatt tggccgctat gattcacctt
     5461 ctgattttaa tattagtctg caatcattat tcgttaacgc tgacgatcgt aacacagtta
     5521 ttgaattcgc tagtgcatta aaaatcgaaa atggctcaga aattgttgat gatggcattg
     5581 gtcaaactgc cacaattaaa caaggtgtgg caagccttgc aaaagctaag gcgccaaacc
     5641 cagttacatt acgtccatac cgcacatttt ctgaagtaga acaaccttca agtgagttca
     5701 ttttccgcat taatcaactt gctaatatgg ctttgtttga agcagatggt ggaaagtggc
     5761 gcttagatgc tatcaataat attgctaact acttaaaaga agaacttgct gatcaaacta
     5821 acattacaat tttagcttaa tagaaaatag gagaaataaa aatgactgaa tacaataaca
     5881 acttcgacca tgaattggga tgggatgatg aaattacaca agacagtgta ggttttgtcc
     5941 aattagtgcc tggtgattat caatttacag taactaatat ggagcgtgct cgtcacacac
     6001 ctgatccgca gaatccagga aaattaccag cgtgtaacaa ggcggtcgtt acgattcaaa
     6061 ttgaaacatc agaaggaatc gcgcaattaa ctcataactt attcctatat actacaacag
     6121 aaggtatgct atcagctttc tttggtgcta ttggtcaaaa gaaacatggg gaaccactta
     6181 aaatgaattg gaatactgtc gttggtgcaa aaggtgtctg tcgtgtaaat aagcgaaaag
     6241 gaactggtaa atatgctgat caagaatacg ataacatcaa atctatgatt tatgcagatg
     6301 aagttgattg gtcgaaagtt ttgaacgcta gtcaaccaac acaaaatact tatcaacaac
     6361 cgcaacaacc aactcagcaa caacctcaac cgcaacaggg aagtttcttc caaggtaata
     6421 caacacaacc acaaggtgga tggggaggat tctgatgcaa ttaaggccgt atcaggaaga
     6481 ggcacggtca gccgtacaaa aggaatggga ggaaggtaga aaacgaactc tactagtcct
     6541 ccctaccggt tgcggtaaaa ctattgtctt ttcgaaaatt atcgaagacc gtgtaaggct
     6601 cggagagaga gttttggttc tagctcatag gtctgaactt ttagaacagg ctagtgataa
     6661 attgatgaca gcaactggat tagggacagc attagaaaaa gcagagaata cttctttggg
     6721 gtcatggttc agggttgtag ttggatcagt tcaaacgatg cagagagaga agcgtttgag
     6781 taagtttcct gcaaatcatt ttgacacaat tattattgat gaggcccacc atgccatctc
     6841 tgacggttac caaagagttt tgcaacattt tgatagtagc aatgttttgg gagttacagc
     6901 gacaccagat cgtggtgaca aacaaaatct aggtaaatat ttcgatagtt tagcttatga
     6961 atattctttg gtagatgcca tcaaatctgg ttatctatca aaaatcactg ctgttacaat
     7021 tccactatca ctggacttaa cgactgttag tcagcaagca ggagacttta aagctagtga
     7081 catcggaact gccttagatc catatcttga gcagattgcc gatgaaatgg tgaagcaatg
     7141 tgcaaaccgt aaaacagttg tatttcttcc acttgttaaa acttcccaaa aattccgtga
     7201 tattctaaac caaaaaggat tcaaagcagc agaagtcaat ggagaatcca aagaccgtgc
     7261 tgaagtccta gaagactttg ataatgataa atataatgta ctatgcaatt caatgctttt
     7321 aacggaggga tgggattgtc caacagtgga ttgtgttgtt gtattgagac caactaaagt
     7381 acgagcactg tatagccaaa tggtagggcg tggcacacgt cttgcaccag gtaaggaaaa
     7441 tctattgctt ttagacttcc tttggcacac agaacgtcac gaactatgca gaccagcgca
     7501 tctgattgct agtagcccag aagtggctca aaagatggtc gagaatatga ctgaagaaac
     7561 cgaggtggct tttgagctta tcgaggctga agaagtagct gccaaagatg tcgtagctga
     7621 gcgcgaggaa gcactggcca aacaattggc agaaatgcgc aagcgtaaac gtgctcttgt
     7681 tgatccgcta caattcgaaa tgtctatcca agctgaagat ttagcagatt atgtcccagc
     7741 atttggttgg gagcaatcgc caccatctga taaacagcta gaagcacttg aaaaatttgg
     7801 catttacaca gacgatattg gcaatgctgg taaagctact aaattattag agcgattggt
     7861 caagaggaga gaaactggcc taacaacacc taaacaaatc agaacgctag aacgatacgg
     7921 ttttaagaat gtgggcatgt ggaaatttga agtagcatca aacatgatta accgcattgc
     7981 tgctagcgga tggcgcctac cgaaaggtat caatgctcga gaataccaac ctgaatagga
     8041 gacaaaataa atggaaaata tgaatgaaca aattgaaaaa tttattaatg attttgtaaa
     8101 tgaagctatc gaaaaatctg atacatacgc tgatgccatt ttgtatgtta ataagattgc
     8161 atctcttaca gagttaggcc aagtaattaa aaaagctatt caagacaaaa tcggtgaatg
     8221 tgccttaaat agcaaaatta attaatatca gacaaagaaa ggataacatg gcagagaatg
     8281 attttaattt gctaccgttg ctggattata tcaatcctgc cacagtagac tatcaaactt
     8341 gggtccaagt aggaatggcc ttaaaacacg aaggatatac tgctatggat tgggatgttt
     8401 ggtcacaatc tgacagtaga tataaaaagg gtgaatgttt cgctaaatgg gatagtttcc
     8461 aaggtaatgg gcttgggact gtcactggtg caactatcac acagttagca aaagacaacg
     8521 gttgggtatc tgaataccgt acgagtgatg aagcccacga gcttggttgg gacgacacaa
     8581 tcgatcgtga ttataaaatt gtggataaga actgggttga ggctaaggaa attaaagaac
     8641 ctactaactg gtcaccagtt cacgatttga ttacttacat cgacactctt tttgaatcga
     8701 ccgacaaagt gggctatgtg acaaaaacct acccgattga gacagatgaa ggggtagtct
     8761 acaaaccaac aaaaggggac tacgcacgta cagcaggcga acttatccaa gagttgcaaa
     8821 aatacggaaa cgacatcggt gctgtgcttg gcgactacaa agaagaagct ggggcatgga
     8881 tccgatttaa ccctttagat ggcaatggcg tcaagaacga caatgtaaca gactttaggt
     8941 atgccttggt tgaatccgat agcatggaac ttggtaaaca gtatgcttta tttaaagaac
     9001 tagaattgcc aatagcgaca ttggtccata gcggtaaaaa atcattacac gctattgtca
     9061 aagtagatgc tagagattat caggagtacc gcaaacgggt tgattacatc tatcaaatct
     9121 gtaagaaaaa cggtcttgat attgacacac agaatcgtaa tccaagtcgt ctatcacgaa
     9181 tgccaggtat tatgcgaaac ggtcacaagc aatttttgat tgatacaaat atcggtaaaa
     9241 ccaattatga agaatggtat caatggattg aagatttaaa tgatgattta ccagagcctg
     9301 aaacgctagc tgatgaatgg gataatttgc cagagctggc tcctgaatta attaaaggag
     9361 tgttacgcca aggacataaa atgctaattg caggaccatc aaaagccggt aaatcatttg
     9421 cattgattga gttatctatc gctttagccg agggacagaa atggttaggc tggcaatgtg
     9481 aacaagggaa agtcctctat gtcaatttgg aactggacag accatcagct ttgcatcgct
     9541 tcaaagatgt ttatgatgcg atggggttac ctcctactaa tgtggcaaac attgacattt
     9601 ggaacctccg tgggaaaaca gtaccaatgg ataaattagc acctaaactt atcagacgct
     9661 cactgaagaa aaattaccaa gcggttatta tcgaccctat ttataaagtg ctcactggtg
     9721 atgaaaacag tgctgatcag atggcccatt ttacaaatca atttgataag gtagccacgg
     9781 aacttggatg tagcgtaatt tactgccacc accattctaa aggaagtcaa ggtggcaaaa
     9841 aatctatgga ccgtgccagt ggttctgggg tatttgctcg cgacccagat gctttgattg
     9901 atttagtaga gctggagctg actgatgagt taatcaagca acgtgttgaa aaggcatctg
     9961 ctaaggttta tcagaaagct ttgcaggaac agaacctttc ttactatcag catgaagtga
    10021 cattagacga tttagaaagc cgctatcaaa tgcaacaaca ttttgacaag gcgataccag
    10081 atatcatgct aaaacagcca tatctgaacg aaatcaagag aattactcac gctattgaaa
    10141 tcagtacagg ctggcgagtt gaagggactt tacgtgaatt tgctaaattc cagccagtta
    10201 acatgtggtt tagctatcca gttcatgaag tcgatacaac tggtgtgttg gcagatatac
    10261 aactggagga aagtaagccg aactggcaga aagctaagga aggtagaaag tcaaaaaaag
    10321 aaaaggcaga ggaacgtaag caaaaaatag atacagccta cagtgctcta tttgatggct
    10381 tcacacccgt ttcattatca gagttgcaag agtatctgga ttctaccgaa aaaacagttc
    10441 gaaatcatct caaagagcat ggtggttttg atattaaaaa cggaattgtc tatcagaaaa
    10501 aaacagaata gggaaagaaa ataacagaaa attttccctg taaaaaacag agaattttat
    10561 gttattttcc cttcctaaat cctgtaaaaa acataaattt tccctttttc taaatcctgt
    10621 aaaaaacaga gaattttatg ttattttccg gaaaaagaca cgctataact cttatcagag
    10681 ttattaaaag tgtttttcct tcgtcaaaag tcaaagaaaa aggaaggttt ggcgttagac
    10741 tt
//
LOCUS       DAUNLR010000054        10607 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUNLR010000054 DAUNLR010000000
VERSION     DAUNLR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10607
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.054"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            20..1267
                     /locus_tag="VLL59_001474"
     CDS             20..1267
                     /locus_tag="VLL59_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HER6509592.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            1541..2902
                     /locus_tag="VLL59_001475"
     CDS             1541..2902
                     /locus_tag="VLL59_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HER6509593.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            2902..3738
                     /locus_tag="VLL59_001476"
     CDS             2902..3738
                     /locus_tag="VLL59_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HER6509594.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            3925..4541
                     /locus_tag="VLL59_001477"
                     /pseudo
     CDS             3925..4541
                     /locus_tag="VLL59_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611920.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(5056..6039)
                     /locus_tag="VLL59_001478"
     CDS             complement(5056..6039)
                     /locus_tag="VLL59_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HER6509595.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGLSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(6070..7320)
                     /gene="dltD"
                     /locus_tag="VLL59_001479"
     CDS             complement(6070..7320)
                     /gene="dltD"
                     /locus_tag="VLL59_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HER6509596.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(7313..7552)
                     /gene="dltC"
                     /locus_tag="VLL59_001480"
     CDS             complement(7313..7552)
                     /gene="dltC"
                     /locus_tag="VLL59_001480"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HER6509597.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(7570..8826)
                     /gene="dltB"
                     /locus_tag="VLL59_001481"
     CDS             complement(7570..8826)
                     /gene="dltB"
                     /locus_tag="VLL59_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HER6509598.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(8823..10361)
                     /gene="dltA"
                     /locus_tag="VLL59_001482"
     CDS             complement(8823..10361)
                     /gene="dltA"
                     /locus_tag="VLL59_001482"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HER6509599.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(10373..10516)
                     /locus_tag="VLL59_001483"
     CDS             complement(10373..10516)
                     /locus_tag="VLL59_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HER6509600.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT         3427 a         2124 c         1807 g         3249 t
ORIGIN      
        1 atcttaggag gaaatagcta tgaaatcatg gcaaaaagtt atcgtcggcg gagcaagttt
       61 gacacttgca agtaccttgt tagtgggatg tggatcaggt tcaaaagata aaaaggaagc
      121 tggcgctgac tcaaagacta ttaaactttg ggtaccgact ggctctaaaa aatcatatgc
      181 agataccatt gcaaaatttg aaaaagattc tggttacacc gttaaagtgg ttgaatcaga
      241 agatccaaaa gcacaagaaa aaatcaaaaa agatgcctca actgctgccg atgtcttttc
      301 acttcctcat gatcaacttg gtcaacttgt agaatctggt actattcaag aagttccaga
      361 aaagtacaat aaagaaattg ctgctacttc tactgatcag gcgctcgtcg gtgcacagta
      421 caaagggaaa acatatgctt tcccatttgg tattgaatca caagttcttt tctacaataa
      481 atcaaaatta gctgctgaag acgttacttc atatgataca attactacaa aagcaacttt
      541 tggtggtacc tttaaacaag ctaacactta cgctactggt ccattattca tgtcagttgg
      601 taacacttta tttggggaaa acggtgaaga tgtaaaaggt actaactggg gcaatgaaaa
      661 aggcgctgct gttcttaaat ggatcgcaga ccaagcttca aataaaggtt ttgttagctt
      721 agatgctaac aacgttatgt ctaaatttgg tgacggttca gtagcttcct ttgaatcagg
      781 accgtgggac tatgaagctg ctcaaaaagc tatcggtaaa gaaaaccttg gtgttgctat
      841 ttatccaaaa gtaactattg gaggcgaaac ggttcaacaa aaagcattct tgggtgtaaa
      901 actttacgca gtcaaccaag caccagctaa aggtgataca aaacgtatcg cagctagcta
      961 caaattggca tcctacttga ctaatgctga aagccaagaa aaccaattca aaactcgtaa
     1021 cattgtccca gccaacaaag aagttcaatc ttcagaagct gttcaatcaa acgaacttgc
     1081 taaaaccgtt atcactatgg gttcttcttc agactacact gtcgtaatgc caaaacttag
     1141 ccaaatgggc acattctgga ctgaaagtgc tgctattctt agtgatgcct tcaacggtaa
     1201 aatcaaagaa agcgactacc ttactaagtt gcaacaattc gacaaagata tcgctgcaac
     1261 aaaataatat gatctcatgt catcactgct atactaaaac aagcacaagg taagtacttc
     1321 taaaaagttc tttccactta ccttatgaag agtggaacta ggctccatca cattttattc
     1381 aagcttagtc tcactcttac ttgtttttgt tttactagta gcttagtgct acttaaattt
     1441 ttaactcttt aaaagtttac gtaacactta gctatttcat cctaacaaga gattgaatct
     1501 gaactaccac tctagtatcc taaaataaag gagaatctat atgactcagt caaacttgac
     1561 accaaatata tctgtaatag aagccttaaa aagaggcagt tgggatatta aactttcgag
     1621 tattatcatg ggatttgcca actttgctaa caaacagttt atcaaaggaa tcttattttt
     1681 aataagtgaa cttatctttc tagtagcttt tgtctcccaa atcatccctg ctatccgtgg
     1741 ccttgtcact cttggtactc aaactcaggg aatgactaca aaaactattg atgggattaa
     1801 catccaagtt gctgttgatg gtgataactc tatgctaatg cttatttttg gtttagcatc
     1861 actcattttc tgcctagtct ttgcttacat ttactggtgt aatctcaaaa gtgctcgtaa
     1921 cctttatctt ttcaaacaaa aaggtcagaa gataccaagc ttcaaagaag atcttgccac
     1981 acttacaaat ggtcgctttc atatgacttt aatggctatc ccactgattg gtgtgctttt
     2041 attcaccatt cttcctttga tttacatgat ctgtttggcc tttaccaatt ttgatcataa
     2101 tcacttgcct ccaaaatctt tatttgattg ggtgggactt gctaactttg gaaatgtttt
     2161 aagcggccgt atggcaggaa ccttttttcc tatcttctca tggactttga tttgggctgt
     2221 ttttgccaca gtaactaatt tcttctttgg tattattctt gctttgttaa tcaataccaa
     2281 aggattaaag tggaaaaaaa tgtggcgaac catctttgtt atcaccattg cagttccaca
     2341 attcatctca ttattgatta tgcggaactt actcaatgac gaaggcccac taaatgctct
     2401 tctcaataaa atcggcttga ttaatggctc actgccattt ttatctgatc ctctttgggc
     2461 aaaattctca atcatttttg tcaacatgtg gatcggtatt ccatttacca tgttgattgc
     2521 gactggtatt atcatgaacc ttccaagtga acaaattgag gctgctgaaa ttgatggcgc
     2581 tagcaaattc caagtcttca agtctatcac gttccctcaa attctcttga tcatgacacc
     2641 aaacttgatt caacaattta tcggaaatat caataacttt aacgtcattt acctccttac
     2701 tggtggtggt ccaacaaatt cagaatacta tcaggcagga acaacagact tgctggtcac
     2761 ttggctctat aaattaaccg tcacagctgc tgactacaat ttagcttctg ttatcggtat
     2821 cttaatcttt acagtttcag ctatctttag cttacttgct tatacaagga cagcatccta
     2881 caaggaagga gcggctaaat aatgaaaaac aaacgtcgat ttcaacttgg acttgtttat
     2941 gccactttaa tcatcctctc aatcatttgg ctcttcccaa tcgcttgggt tattcttact
     3001 agcttccgta gcgaaggaac tgcttacgtc aattatttta ttcctaagac ttttacatta
     3061 aatcactaca ttaatctttt tactaatgaa acctttcctt ttggaaaatg gtttatgaat
     3121 actcttattg tagccacttt tacatgtatt atttcaacct tcataactgt tgccatagcc
     3181 tactctctta gccgaattaa gtttaagttt cgcaatggct ttttaaaact agcccttatt
     3241 ttaaatatgt tccctggttt catgagcatg attgccatct actatatctt aaaggcctta
     3301 ggtttgacgc aaaccctaac agcacttgtc cttgtttatt cctcaggtgc agcccttggt
     3361 ttttacattg caaaaggatt ttttgatacc attccttatt cacttgatga atcagctatg
     3421 attgatggcg ctactcgtat ggatattttc tttaaaataa cccttccttt agcaaaacca
     3481 atcattgtct atactgccct tcttgctttt atggggcctt ggattgactt tatctttgca
     3541 caagttattt taggtgatgc tacaagtaaa tataccgttg ctattggact attttcaatg
     3601 cttcagccag ataccattaa caactggttt atggccttca ctgctggttc tgtcttaatt
     3661 gccgtcccaa tcactctcct cttcatgttt atgcaaaaat actatgttga aggcatcaca
     3721 ggtggttctg ttaaataagt tacaacatac caaaccttct aagggcaagc cctttaggag
     3781 gttttcgata aataaggccg tagataatca tattagtcct cacatttatc ttcagatccc
     3841 gcgttataaa atgaagtaca acaaaaaaga catgttcgtc tgatatacta gaattcccca
     3901 attcagtatg gaaagcagat gaacatgtct aatattaatt ttaccagaaa atcctcctat
     3961 tctcatcttt cagccacaga acgcggtgaa attgctgctt atcttaaaat gggaaagaaa
     4021 cccgttgaga ttgctcgact tctggggcgt cactgttcta caatctgccg agaaataaaa
     4081 cgtggttcag tagatcaggt aaaggataag aatggaaaac aaaccttctt caacgcctat
     4141 ttcgctgata gtgggcaacg tgtctattaa accaatcgat ttgtctaaga tggttagtat
     4201 cagaaaacgt tctaagaaag tcatgaagac gaataagaag actttaggta aatctatcga
     4261 agaacatcca gaatatatta gtgatcgttc tgaatttggg cattgggaga ttgatttggt
     4321 tctcggcaag aaaaccaaaa gtgaagctgt tatgttgact ttggtagagc gccagacacg
     4381 ctatgcacta agagttaagc tagaagacaa gccgtcccaa accattaacc gtgctgtcac
     4441 gcatctcatc agtcagtatc ctattgcatc catcacagcg gataatggtt ctgagtttag
     4501 tttactctca caatgagcgc ccaagacgac ttcttcaata gcaatcctca acattcctgt
     4561 ttgagctatc ccaaacagct taacctctgg aactctagtt atctatgaac tcgttgcact
     4621 tgacttgaca acttgcgaga gcatatcagt agtttttctg ctaattgaaa acatggtatt
     4681 tactgtcaca caagtctgtc ctttcttttt tttctacaac tttatttcgt cagcgtaaat
     4741 aaaacaaaag ctctataatc tcttgaatgg gtaaatccac tgtagagatt atagagcttt
     4801 ttgaatatca aaaaagtccc ataagattta taatgaaaag caaccaaact ctcattagaa
     4861 agactcttat ggaacatatc aatcatacct tacaacacat cggaattaaa gacaaaaata
     4921 tcactctaaa caatgttttg aaggatgaat ctcctactga gctcgttact acttatcaga
     4981 aaggtagata ggaaatcctg atgaagagtg tgtccaaggg attatcaatt aggtcttaga
     5041 ttacaaaata gtaattcagg tatgctctac tgttttcaac actagttctg caatttgttt
     5101 tcgagcttgc ttagcttctc ttattggaaa aataacatac gcatgaatca ttttttctgc
     5161 aataatcagc tgattagcaa ttcgttgtct tgttaattga tcatgtaaag acataatgtc
     5221 tgggtaaaaa atctcttttg tcccaacaaa ggtcgttatt tcaggcaaat cctcataatc
     5281 accatacaaa ggactgacat aaggaagttg catattacct tgaccacctg cccatagttc
     5341 acctatatca cgaagacgac gagcatctag gtaagcttct tctgcttcaa aatccttgta
     5401 ggcttgattt ttaaaactaa catctaacca aggagatata agaattaatt gctttggctg
     5461 gggtgctgtt ttagtatctc gtatatactt agcaaacgcc aaagccatac ccccaccaga
     5521 agaatcacca atgacactaa cttgactcag tccattagac aagcaaaatt gctggtaagc
     5581 ttcaactaat ttaggataga catcttgata agtagcatac ggtactttag gaaagttagg
     5641 aaaaacaacc ttggcattag tcagctgtat aagatgctta accgtcttaa aatgaagttt
     5701 ttcgggtcgt cgtaaataga cactgccata aagataataa ataacaggct gatgactttg
     5761 cttttgatca ttaataataa aaacttgcat cccgttcaca tcgtattctt gagttgaaaa
     5821 acctactatc tcttcaggat tatctagatg ataagggata ttacgattac gctgcgtctc
     5881 aaccccctta taattatcaa cttttttaga taacttatac tttctataag caaacatttt
     5941 ctcaaccaac caacttgaaa aggagcgctt ttgaccatat tcaactatca aaatacctag
     6001 tatcactcca aaaaaaatca ccacagcaat aatgaccact tattatcctc gttttctaat
     6061 attattttac tattgcaagt ctttcctatt tgcccaaatt ttactataaa aataagggtt
     6121 cattttatag ttgggcactg gctgcttcgt ttctagaaat ggttgcactt tcttatcaaa
     6181 agctaaccag ccattccaac cgagatggat ggtatcttgc ataaagtagg actcaccacc
     6241 atcttttgag aagtcagcaa tgcgatgaaa tccttgtgac tttaactgga attttatttt
     6301 acgaactgcc gcttgatact tatcttgatt taagccggta taatccgccc aagctttatt
     6361 aacaggagtt ataacaaaga gtacatctgt ttttcgttta gcaaattctg ataataaaag
     6421 ctgaaaatca ttgtattctg gtgacgccag gtaactataa ttaacttgga aattcttata
     6481 aagattgtat ttaggtgcta ttcgtttacg ataaaatgta tttttaatcc caaaacggtt
     6541 gttggttgtt gctaattggc ctctcttagt tgctaatgca ttcaattgtt tatacgaaaa
     6601 tactttaggt aatcccttaa cgcgaggcaa aattcttttt tcatagttag tagatttgcc
     6661 taaaaaacta aaaagggact cttctctcaa tgctacttga tgttgacatt tcaaaatagc
     6721 tctgtctaac cgactaagag acttaccctt acttactttt ttcaataagt ttgatttaga
     6781 cacaccaggg ttaagctcaa gcaaacgctt tgctgcaaac tgtgattctt tatcagttct
     6841 agcttttagt aaaaattcaa tcacttgagt gttagacaag tacatctgaa ccgcactagg
     6901 attaatccct tgagcagtaa accattgagg agatactaca aagatggctt ttttcttttg
     6961 catttcattg gtaatttgtt gcataccata ataatgcgac aaagatgctg atcctctctt
     7021 accaattaaa aatggtctat agctccgctt gtagcgctct gcaagcaccg aagggtgcat
     7081 actatccatt cgactccatt cgctagaacc aaaaaaaggc acaaaacgac aagtctcatc
     7141 tgataaagct tgtcttttaa tcaaaccatt tttaaaagaa ctatctgtga tcgcaacggc
     7201 atttgctttt tcctgagcta tggaatgatc aagttgtgtg ggaaaactaa aaatagtaat
     7261 cactactaaa acaaaggcaa taagaagagg acctagaatt aaccagagtc tcttaagcat
     7321 gttgcaattc ctctacacct tgaacaatct tagttactgt gttccaatca tcacgaccaa
     7381 attctgaaat aggtacttta atattgaacg ttgactctaa ctcaacaatc aattcgactg
     7441 tcccaagact atccaacaca cctgcatcaa acaagtcttc gtccatcatc tctgaaacat
     7501 cttccataaa caaacggtca aacaattcaa ttacagtttc ttcaatagac atttttatac
     7561 ttccttttat taatgtagtg gtctgttaaa ccaaaggtca tttaaaaaac cagagaataa
     7621 cagaagtgaa aacatgacaa cgtggaaagt taccacgata cataagacat ggaatgccct
     7681 gctttgaaag aggggtgata agcctttttt cttacggtga cggttgattt cttttttctt
     7741 acgaatccaa gcatcattaa taataagtcc tataccatgg aaaagcccat aagcgatata
     7801 ataccaggtt aagccatgcc aaaatcccat gactagcata ttaaccagat aggcaacacc
     7861 tgaagtgaca tttcggtttt taaaggtttt atgcttaatc aatagatgaa ccaatcgcat
     7921 aaacacataa tctctaaacc agaaggacaa actcatgtgc catctattcc aaaaatcttt
     7981 caaacttgca gataagaaag gcatgttaaa gttttctggt gttcgaatac ccaataggta
     8041 ggaaatacca atcgcaaaca tcgaataacc agcaaagtca aaaaagagat tcaagccata
     8101 cacgtacata accagaatag tttccttatt aaagtagcca ccaaccatca aagccttatt
     8161 ttcaaggaga ggaagtaaga tgccacccaa acaataggaa atgatatgct tgtatagaaa
     8221 acctaacatg agatacatga ctgccttatt gagcattgca aaataatcat cacgttcagg
     8281 aagtttatga taatcttcct gaaaacgtct gaagcgatca atggggccac ttgagaaagt
     8341 ggggaagaaa atcatgaagc gaataaaatc cggtaaacga acctcttgga gagtcccgtc
     8401 acgcatctca ataatcattc caatactttt aaaggtcaaa tatgaaatcc ctagaaaact
     8461 aaagagtgtt tgagaagaag gacctgttag gggagcaact ttgacccaga taagggggaa
     8521 taaggccatc gcaatagcta agtaaaacac tcctgcacta ttagctttct cacggtattt
     8581 ctggtaagca aaaacactga tgatttgcca caaaagataa aagagaaaag caactaattg
     8641 ttgataatga tctcctccaa acataaagag aataaatacc aaactcacca aggtttcata
     8701 agtgcttaag cgcttttgtt taaaaatccc aatgatgact ggtaagaaag ccaaaataag
     8761 atagacaaag taaatggggt taccgtaagg ttccatgtag ggaatgtggc taaaaaacat
     8821 catcatcggt tattgacctc attaatcaaa gttttaatat ctatcttacc atttggagtt
     8881 aatggtagac tatctcgata aagaaactta gaaggcatca tataactcat catatgatcc
     8941 ttaacagagg ctttgatagc tttggttaac tccaattccc tatcaaaacg ctctttaacc
     9001 ccatctttga caacgatata ggccaagaga ttttgaacct tatgttcttt attgtacctt
     9061 ggaacagcca cagccgatgc taccattggt gattgattca actgttggga aacatcttct
     9121 agttcaatac gataaccagc atatttaatc tgaaaatcca aacgcccacc atacagcaaa
     9181 atattatctt ctgtcaatga gccaatgtcc cctgtatgat aagcaggctg tcctttaaaa
     9241 gtaaagaaag cttctgcggt tttctcagga ttgttgaggt aaccttttga cacagcaggc
     9301 cctgtaacaa taatttcacc ctgctcccct gaagataact ccttaccatc ttcatcaata
     9361 atataggtcg gagaatctgg tttggggtag ccaatcggca atcgggtata attatccacc
     9421 atttctctag taatttcaat agcggataag gctacagtcg cttctgttgg tccataggca
     9481 ttgataatct tggcactcgg gaaacgttca aagagttttc gagccgtaga aacggttaat
     9541 tcttcgccat caaaataaaa atgcgttaaa gctggcatct tagcctggca aaaatcatcg
     9601 ctaagcatgg ccatatcagc aaatgaagga gtcgatgtcc aaatgccaac tggaagttgc
     9661 gcaatcgttg taaataactg tttaaagtct gccaccaatt cttttggaag tgcaaataag
     9721 gttccaccta aagccaaggt aggtgcccag tacatgacag aaaggtcaaa ggaatagggt
     9781 ggctgcgcca gcatttgtgg ctgtttaggt acatcaaatg ctgcatcttc gatcatccag
     9841 ttggtaaagc tcaaaagatt gtcatgtgaa atttgcaccc cttttggttg gcccgttgtt
     9901 ccagaggtga aaataatgta ataattatca tctcctttaa cagaatgtgt tcgctcatag
     9961 ggcatttctg ctaattttgc tgactcaatc tctgatagtg agacaaggga aatcccttca
    10021 atagtaagag ggaattcctc aatagcaatg attaaactgg gctttgcaat ctcaataatc
    10081 gctaaaatac gttctggtgc tgaatgcaca tctactggga tataggcatg accagatttg
    10141 gttaaagcta caaaagtagc taacatatca taagtttgcg ccccaaaaac caaaactgga
    10201 gattttgcca gtaaagctaa gctatctata aatgcagcaa tgctatcaga atctcttttg
    10261 agttgtccgt aagtgcggcg ttcccctaaa caatcataaa ctggaaaatc agcctgtgtc
    10321 tgagcaaact gctcaatact gtcaatcata tccttaatca tcagtcaatc tcctaaaatt
    10381 cattataaat aaagttactt tgaccatgtc ctagataacc aaagaaatag accagcaaca
    10441 ttaaaatcag ataaaataaa attgtcttgc caataaaaac agcaattcct ctcattcttg
    10501 atttgttttt tatcatactt taccttcttg tattagtgaa ataatgtcct aaaaaattct
    10561 actcgaaaaa acctaacttg acaagctaaa agtcatatta ttaaaaa
//
LOCUS       DAUNLR010000055        10575 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUNLR010000055 DAUNLR010000000
VERSION     DAUNLR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10575
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.055"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            261..389
                     /locus_tag="VLL59_001484"
     CDS             261..389
                     /locus_tag="VLL59_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HER6509601.1"
                     /translation="MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM"
     gene            446..1759
                     /gene="obgE"
                     /locus_tag="VLL59_001485"
     CDS             446..1759
                     /gene="obgE"
                     /locus_tag="VLL59_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HER6509602.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEVTA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD"
     gene            1828..1986
                     /locus_tag="VLL59_001486"
     CDS             1828..1986
                     /locus_tag="VLL59_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509603.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(1991..2686)
                     /locus_tag="VLL59_001487"
     CDS             complement(1991..2686)
                     /locus_tag="VLL59_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HER6509604.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILITLIFYSILASIQTAYLLVSTLSIATSFSA
                     IYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYNWL
                     MLQRYQEKKVKKG"
     gene            2911..4311
                     /locus_tag="VLL59_001488"
     CDS             2911..4311
                     /locus_tag="VLL59_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HER6509605.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDLLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            4320..5414
                     /locus_tag="VLL59_001489"
     CDS             4320..5414
                     /locus_tag="VLL59_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HER6509606.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFISAQSASESPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVRKDYLSLLDDLRPWQEFCLEIDPS"
     gene            5519..7513
                     /locus_tag="VLL59_001490"
     CDS             5519..7513
                     /locus_tag="VLL59_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HER6509607.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEGSVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFLTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLAAFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            7536..7847
                     /locus_tag="VLL59_001491"
     CDS             7536..7847
                     /locus_tag="VLL59_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HER6509608.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIEVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            7850..8185
                     /locus_tag="VLL59_001492"
     CDS             7850..8185
                     /locus_tag="VLL59_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HER6509609.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            8182..8631
                     /locus_tag="VLL59_001493"
     CDS             8182..8631
                     /locus_tag="VLL59_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HER6509610.1"
                     /translation="MIISAEGDVSVHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKEHTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANHFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            8809..10188
                     /locus_tag="VLL59_001494"
     CDS             8809..10188
                     /locus_tag="VLL59_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HER6509611.1"
                     /translation="MSHFSDKFMDLSGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            10185..10337
                     /locus_tag="VLL59_001495"
     CDS             10185..10337
                     /locus_tag="VLL59_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509612.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
BASE COUNT         3171 a         1864 c         2327 g         3213 t
ORIGIN      
        1 tttcttgatt aaatttcata aaaaaatagc accccaatcg ttagattttg tgtctaactt
       61 ttggggtgca gttcaccaga cgaggaggtt tttatctgta acattatttt gcaaatgcta
      121 atgtatcata ttcatatgaa attcacaaga tacaatactc agtaatagtc tacatagcgt
      181 aaatattcat ctggtatttg cctaaaacga tctttcatgt taatatataa gaagaaaaat
      241 caatagatga ggtatttaac gtggcatttg gagaaaatgg acctcgcaaa aaaacaacct
      301 ttgaaaaagt aacaatgttt gttgttatcc taatggttct tgtaactgtt ggcgggctta
      361 ttgcgagtgc cctatcagta ttaatgtaag gaaacgctga aaggcgtttt tttaaagtaa
      421 aagaaagtta gagaataaaa aaagtatgag tatgttttta gatacggcaa aaatcagtgt
      481 ccaagcaggc cgtggtggcg atggtatggt agcttttcgt cgtgaaaagt acgtcccaaa
      541 tggcggtcct tggggaggag acggtggtaa aggtggctca gttatcttcc gagtggacga
      601 aggtttgcgt accttgatgg atttccggta taatcgtaaa ttcaaggcga aatctggtga
      661 aaaaggtatg accaaaggca tgcacggccg tggtgcagaa gatttgattg tctttgttcc
      721 tcaagggaca acggttcgtg atgctgaaac tggaaaagta attacagact tagtagaaca
      781 tggtcaagaa gtggtcattg ctaagggtgg tcgtggtggc cgtgggaata tccgttttgc
      841 aactcctcgt aatcctgcgc cagagattgc tgaaaatggt gagccaggtg aggaacgtca
      901 gttagagtta gaactcaaaa tcttagctga cgttggcttg gtcggattcc catctgttgg
      961 gaaatcaacc ttgttaagtg ttgtgtcatc agctaaaccg aaaattggtg cctatcattt
     1021 taccactatt gttcctaatc ttggaatggt tcgtacaaag tcaggtgata gctttgctat
     1081 ggcagatctg ccaggtttga ttgaaggtgc tagccaaggg gttggtttgg gaactcaatt
     1141 cctccgtcat atcgagcgga cacgggttat tcttcatgtg attgacatgt ctgctagtga
     1201 gggtcgtgat ccttacgaag attatgtttc tattaataac gagctggaaa cctataattt
     1261 gcgattgatg gagcgcccac agattattgt ggctaataaa atggacatgc cagaggctca
     1321 agaaaacttg aaagccttca agaaaaaatt ggctgcccaa tatgacgagt ttgatgattt
     1381 gccaatgatt ttccctattt caagcctagc acatcaaggc ttagagaact tgttagaagt
     1441 aacggcagaa ttacttgcta agacggatga attcttattg tatgatgaat ctgatctggt
     1501 ggacgaggaa gcttactatg gttttgctga gactgaaaaa gactttgaga tcacacgtga
     1561 cgatgacgct acttgggtct tgtctggtga gaagttagaa cgtctctttg tcatgaccaa
     1621 tatggaacgt gacgaatcca tcatgaaatt tgcccgtcaa ttgcgcggta tgggggttga
     1681 cgaagccctt cgtgaacgtg gagcaaaaga cggggatctt gttcgtattg gcaaatttga
     1741 atttgaattt gtggattaag gcaatccatt acaatagcag tgtgatagtg ctcttgtgtg
     1801 ttatctttaa gatggaggtt tctgattatg ggtgataaac cgatatcctt taaggataag
     1861 gatggaaatt ttgtatcggc agcagatgtt tggaatgctg agaaattaga agaattgttt
     1921 aatcttttaa atcccaatag acgtttgcgc ttagaacgtg aaaaattgaa aaaggatgag
     1981 gcttaggccc tcatcctttt ttgacctttt tttcttggta acgttggagc attagccaat
     2041 tataaaaagt gtaactatca ttaataagaa aggtggcaaa gcagatgacc acagcatatt
     2101 ggctggcatc tgtttgagca gcatgcatcc ataagagaat gaggactaga tcattgagcc
     2161 cgtatgctaa agcaaaataa gggctgcgct tatagctgag ataaatcgct gagaaagaag
     2221 tggcaatcga taaagtggag acaagtaaat aggctgtttg aatagaagcc aagatgctgt
     2281 agaaaataag agtgatcagt atagtaaaaa cgaaaagaca tcttcgatca gtgggtgtta
     2341 atcgtgaaat agtcacttgt gattttttcc cttcaaaagg atggtttaac caagtaaaaa
     2401 gtgaaaaaat agtcataggg agggtcataa aaagataggt cattaactct ccatagtaac
     2461 tgtttcgtaa tgaaagatag gcatagataa tggaaaaaat aatgacgagc ccttgaccaa
     2521 taggattagc tttagcacta aaaatgagag aggtcacacc aatcaaagaa gctattaaag
     2581 ctaagggagc ttgcttaccg aataaaaggg cgctaattaa aatggccaag acagagctta
     2641 accaaagtgc ccactcggtt tttgtaaagt agtttaaata agccataccc ctattcaaac
     2701 ataggctaag gcatctgtca ataggggctt ggttttgata agaagtagca gggcaggtta
     2761 gataggctct ttaagataat aaaatatgtc aagctttaaa tcacttattt tccgtgatga
     2821 taaggaaaaa acagattttt taaagcgttt acatcacctg tttttcttct tataataaaa
     2881 agagaagtga gcaaagaaag gacaaaggat atgaaacaaa gaaaacaccg ttatcaattt
     2941 ccagatggct ttttatgggg aagttccaca tctgggcctc aaagcgaagg aacggttcct
     3001 ggagatggca aaggacctag caactgggat tactggttta gtattgagtc agctaagttt
     3061 catcaccaaa ttggtccaga aaaaacctca accttttatg aaaactataa gggtgacatt
     3121 gcccttttga aagaaacagg ccacacgatt tttcggacct caatccagtg gtctcgattg
     3181 attccagaag gagtcgggga ggttaatcca aaggcggtga cattttatcg agaagtattt
     3241 caagacatta ttgctcaagg tattaaattg attgttaacc tctatcattt tgacctcccc
     3301 tatgccttgc aagaaaaagg tggctgggaa aacaaagcta ctgtctgggc ttatgaaacc
     3361 tacgcaaaaa cctgttttga gctttttggt gatttagtaa acacttggat tacctttaat
     3421 gaaccgattg ttccagtcga atgtggctat ttaggttatt atcactaccc ttgtaaagta
     3481 gatgccaagg cagcagttca agtggcttac aacacacaac tggccagttc actggcggtc
     3541 aaagcttgtc ataagcttca tcccgaccac aagattagta ttgtgcttaa catgacacct
     3601 gcttatcctc ggagtgatgc tcctgaagat gtcaaggctg ctagaatcgc agagcttttc
     3661 caaaccaaat ccttcctaga tccatcagtt ttgggtgttt acccagcaga gttagtttcc
     3721 attttagagg aagctgattt attacctcaa tatagtgctg atgaattaga gattatcaaa
     3781 aacaatactg ttgatttttt gggagttaat tattatcagc ctttgcgggt tcaggcacct
     3841 agtaagtcac agcaagaggg ggacctcctt atcttagata tttattttga accttatgat
     3901 atgcctggta aaaaagtcaa tcctcaccgg ggttgggaaa tttatgaacc aggactttat
     3961 gatattgccc ttaatttaaa agaacactat ggtaacatcg aatggctagt cacggaaaat
     4021 ggtatgggtg tcgaaggtga agaagctttt ttagcagatg gccagataca agatgactac
     4081 cgcatcacct ttatcgagga tcatcttatc cagcttcata aggctttggg agaaggagcc
     4141 aactgcaaag gctacctctt gtggactttt attgattgct ggtcttggtt aaatgcttat
     4201 aaaaaccgat atggtttggt agctttggat ttagagagtc aaaagcgaac cataaaaaaa
     4261 tcaggttact ggtttaaggc gttgagcgag tcaaatggtt ttgataaata ggaggcaata
     4321 tggttgattt aggattttct ctataccctg agcggtatga tgttaccaag agtaaagctt
     4381 atattgactt atgtcatagc tatggagcca agcgcttgtt tatgagtctc ttacagctgg
     4441 caccagctga tcaccagatg tttcattgct acgcagagct cattgcttat gcaaatcaat
     4501 taggcattcg agtgattgct gacgttagtc caagctttat tagccaagct ggttggtcag
     4561 atcagcttat tgaacgagct catgccttcg ggttagcggg cttacgctta gacgaggctc
     4621 tccctctagc agagattgta actttaacaa gaaatccctt tgggcttaaa attgaactta
     4681 atatgagcac tgataaacaa ttattgatgt cattgctagc gacagatgca gaacggagca
     4741 atattattgg ttgccataat ttttatccac atgaatttac tggtttgtca tggcaacatt
     4801 ttaaggatat gtcacgtttt tatcatgagc atgatattga aacggctgct tttattagcg
     4861 ctcagtcagc atctgaaagc ccttggctac tggcagaagg cttgccgaca gtggaagacc
     4921 ataggcactt gcccattggc ctgcaagtag aattaatgaa agcgatagga accattgata
     4981 atatcctcat atctaaccaa ttcatttcgg aagaagaatt ggcagcatgt actcaggctt
     5041 tagcaagacc agtcacaacg atcaaggtta ggcctatcat cgatttgaca gaagttgagg
     5101 agcaaatcat tggctatccg cattgttatc gtggcgatgt atctgattat gtgattcgat
     5161 caaccatgcc acgtctagtc tatgctcagg aatcgattgc tccaagagac caatctaagg
     5221 aggtcaaacg aggtagcatt attattgaca atgaccgcta tcatcgatat aagggagaac
     5281 tgcaaattgc tttgaaaaat tttacggtta gttcaaaagc taatgtggtt gctgaggtca
     5341 gaaaggacta tcttagtttg ttagatgatt tgcgaccttg gcaggaattt tgtttggaga
     5401 ttgacccatc atagattctt tcacaatcaa tgcggaaaat gatggtcacc tttttcagga
     5461 aatatttggt acactaaaag agggtagaaa gcgttttcta aagtagtaag gaggactaat
     5521 gttatcaaaa aaagaactgg ccatcataac atttctaatc catcacaaag agcagtttgt
     5581 ctctagtgca actctggctg aggttattgg tatgagtgac cgtacggtta ggaaatacct
     5641 caaagaactg attagtagcc ttcctgaaca cggagctcac atcatttcta aacaaggtcg
     5701 aggttactgc ttagaaattg accattctat ggcatttgac atcttttggc aagaaagtgt
     5761 gacgtctaaa aaacgtttgg cagatgtgac tcaagtggaa ggatcggttg atcgagaaga
     5821 ttatgtgctt cataaattct tttttgaaga tgccgttcag gattttgaag agctttgtca
     5881 agaattgtat attagtcgga caactttaaa acatgtttta gcaggcatta aggagcgcat
     5941 aataccttac cagttagagc ttgaaataac tcaccaacat attcaaataa gaggtaaaga
     6001 agaggacatt aggcatttta tcatggacta tttttttctt actagttttg ataatacctt
     6061 gtccaccatg gtaggtaata cctttcttga aggtattaat tttgcagaaa tcatgattat
     6121 tgtcttggat gaatgtcggg atgctaagtt gaaactttct gattttgtca tgaataatct
     6181 agtcttgcat attgccctaa tggttcagcg tattcgatcg gggtgtccat tagaattgtt
     6241 ttccattcca atagctattc gtcagtctga tgagtatcaa gtagctctgc gcattttgta
     6301 tcgagtggaa gaagtgatgg ggatacgttt tcctaaagag gaggctaatt atattgcact
     6361 gcatctaaag gtcaaacatt ctgttggtaa gcattggcaa gatgataata ccgatgaaaa
     6421 gttgcaggac catttaaaag catgtattgc caagattagt caattgacag gcatgacttt
     6481 agaaacagat accaatttat ttcaaggttt attagcccac atgatgccct tgaccacacg
     6541 tcttgaaaac catattcagc tgactaatcc tttaactgag gaaattaaaa gccagtatcc
     6601 tgaaatattt acccttacca agcagacctt ttcggatttg cttgtatgtc aaaagaatga
     6661 tgtctcagat gatgaatggg cttatattag tttgcattta atggcggcca ttgagcgtta
     6721 ttcaaaccgt cataaattga gggttctagt agtttgtgcc acaggttatg gtagtgccat
     6781 gatgttgaaa aatcgcttgg aaaaggaatt tgaaggacgt ttgcgtattg tcgatgttat
     6841 cagttactat gaaataaccg aagagcgact gaaaaccgtt gatttgatta tttcctctat
     6901 cagccttgcc aatctgatgt ttttaacacc agtgattact gtcagtgttt ttttgtcaaa
     6961 tcaggatatt gaaactattc gacaatttat tggagaacaa gaaggtatca agaaagaggt
     7021 cagtttaccg tcacagatga gtttagcaaa agcagagcag cttctaacag gtgtttttag
     7081 ccctaatcgt tttctttatt tagacgagaa aatctcaaag gaagacttgc ttttacggat
     7141 gattgcttgt cttgacgagg cgggaacaga aacgtttgta gaggacttct atcatcaaat
     7201 ggtactgagg gaaaattaca gcccagtcat ctatggagaa gtgcttgcct ttccgcatcc
     7261 tgctaatccc atgacttatt ctgaacaggt agtagtggct atttgccgag agcctcttga
     7321 gtgggacaag gcgcatcaag ctgttcattt tgtctttcta ttatccccgt ctaaagggca
     7381 taatcatagg ttaaaatatg tatcaccagg tttggcagct tttgtcaatc aggtggagct
     7441 tcagcaagcg ttactagaag aaccaaatta ttccaaattc atgacagtgt ttaccccact
     7501 tattcatgat taaaacgatt aaaaggagaa accttatgaa atctattatg ttagtttgta
     7561 atgccggtat gtcaactagt atgttggtga ctaagatgca aaaagcagcc caagcgcgtg
     7621 accttgaagt ttctatttgg gcagttcctg tgagtgaagc tgacaacgaa gtggctgcta
     7681 atagcattga agttctcttg ttaggtccac aagtcaaatt cttactaaag gattttaaag
     7741 ataagtttga accagatatt aaagtagatg ccattaacat ggctgattat ggtcttatga
     7801 acggtgaaaa agtccttgaa acagccctag cgatgatgga ggagtaggca tgacggaacc
     7861 atccaactta gaagctatta tgggcttaat catgtatgga ggcgaagcca agggcaaggc
     7921 cgtagaggct attcatgcag cacgagatgg gcagtttgag gaggctcagc acttacttca
     7981 agaagcgaca aactcgttaa atattgccca taaatcgcag acccatttgc tctcccaaga
     8041 agcagctggt gatgcggttg aattgtcttt attgatggtg catggacaag atcacatgat
     8101 gactgcctta gcctttattg atttagccaa ggaattggtt accgtttacg acaaaatgtc
     8161 agcaatacaa agaggtgagt catgattatt tcagcagaag gagatgtttc cgttcatcat
     8221 tgttttgaag ccatgctgat atcgcttcaa gaagattacc ggcaaaatac cttgagacag
     8281 ttgtcaagag atgatattaa agcggggata aactatgtta aacattatgg taaatacaaa
     8341 gagcatacag ttagggtgct tattacggcc ctagaagctc cgcaattata tactgcttgt
     8401 tttagttcca atcatgggat aaaggaattg gcttatcgat tagaggctct gggggagaat
     8461 cggactagaa ttacctattc ttatgactat catcctctag atatttttca aaaagcaaat
     8521 cattttattg ttggcaaact gttcaaaaaa agcctagaac gccaatctca agctcagtta
     8581 gcagccctta tccaatatgc taaacagttg cagcaaccat cgtctttgtg aagattattc
     8641 acagaccttg gatgagagag aagggttcat ttggataaga gtcgattacc ggttatctct
     8701 aagcatcacg tttaacaagg atgattttga gataattgtg ttaggcagac accgctgctt
     8761 ttaaggttac ctttgttaca ttaaaaaaat aaaaagagga gaagatttat gtcgcatttt
     8821 tctgataagt ttatggatct ttcaggaaaa attgggtcac aacggcattt agtagctatt
     8881 cgtgattcct ttatttcaat gatgcctatt accatggcag gttcagttgc tgtcttattg
     8941 aacgtttttt tacgcgatat tccaaacaat atgggatgga cagggtttgc aaaagctatg
     9001 caacctgtta ttgacatcaa tggctatgtt tattttggga caattggtat catggcgctc
     9061 ttttttgcct ttgctttcgg ttacaattta gctgttatgc ataagattaa tccattggca
     9121 ggaggattga tttcttttgg ctcatttatt gccaccctac ctcagacttt aaccatttcg
     9181 acaccacttg aaaatgcctc tgctaaccta attagcaatt tgaaagaaat ggggctttca
     9241 gtcgttactg cgggtggagc ttcaagtatt gaaactagtc aatggggagc aatagctcta
     9301 aagtatgtcg gtgctacagg cttgttcaca gctttaatta ttggcttttt atcaagtttt
     9361 gtgtatgcgg ctttgaccaa acgtaatatt accattacct taccagataa tgtaccacct
     9421 gcggttaata aagcctttgc tgccattatt ccaggaacag ttgcgattta cgcttcggca
     9481 attttcgcct acctcatctt tgcattaaca ggttcttccc taagtgatgt catttcaacc
     9541 tatatccaat taccattact aggcttatca cagggtattg gttcagttat cttgttaacc
     9601 ttcttagttc aactgctctg gttcttcggc ttgcatggtc ataatgtctt agccccagtg
     9661 atggatggta tttatatggt agctttaaca gaaaatacag ctgcttacaa tacagcgcat
     9721 agcgctgcta atttaccata cctttggaca cgcgggtcct ttgatgctta tgctcaaatg
     9781 ggtggttcag gagtaacctt ggcattgatt attgctatct tcatattctc aaaacgagaa
     9841 gagcataaaa ccattgccaa attgtccgca ccaatgggtg ttttcaatat caacgaacca
     9901 attacatttg ggatgccaat tgttttgaat ccaacctttg tgattccatg gctaattgtg
     9961 ccaccaattt gtgctagcat agcttatttt gctactgcaa taggtttgat tccaccggta
    10021 ttcttatcag taccttggat tacccctgtt ggactttatg cttacctagc tactggaggt
    10081 aatattatgg caggtttggt ttcactgttt aacctctttg ttgccttcct tatctgggca
    10141 ccatttgtca ttttggccaa taaagaaaaa gcgagtgacc ttgcatgaca gaaaaaaatg
    10201 gagcaacttt tttaatggct gttggctttt ttctcattgc cattagtccg atggttggta
    10261 acaaatactt acacatagtg acgggactag ctcttacggg attaggttat tacctcacta
    10321 aacataaacg cccataaaaa agcatagggg acactcttat gaaggagaga gtcataagag
    10381 tatccctatt ttgctggttt gaataataac agtaaccaaa aaaggcaagg aaacctgttt
    10441 ccttgcctca gattgaagac aaacatcgat ttggtgtttg tcttttttag tgtttttaga
    10501 taaaaatggc tgtttccgtg cttaaatcac ctcatctgaa caaaataaaa aggctctccc
    10561 gccatccttt tgact
//
LOCUS       DAUNLR010000056         9692 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUNLR010000056 DAUNLR010000000
VERSION     DAUNLR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9692
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.056"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            13..4119
                     /gene="cas9"
                     /locus_tag="VLL59_001496"
     CDS             13..4119
                     /gene="cas9"
                     /locus_tag="VLL59_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HER6509613.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENLINASRVDAKAILSARLSK
                     SRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSDILKE
                     YPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVRVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDIRKMIVKSEQEIG
                     KATAKYFFYSNIMNFFKTEIKLVNGEICKCPLIESNKETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKCVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRVDLSQLGGD"
     gene            4119..4988
                     /gene="cas1"
                     /locus_tag="VLL59_001497"
     CDS             4119..4988
                     /gene="cas1"
                     /locus_tag="VLL59_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HER6509614.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKA
                     LNNEGRGVPEFRI"
     gene            4985..5326
                     /gene="cas2"
                     /locus_tag="VLL59_001498"
     CDS             4985..5326
                     /gene="cas2"
                     /locus_tag="VLL59_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HER6509615.1"
                     /translation="MSYRYMRMILMFDMPTDTDEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5316..5978
                     /gene="csn2"
                     /locus_tag="VLL59_001499"
     CDS             5316..5978
                     /gene="csn2"
                     /locus_tag="VLL59_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HER6509616.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYEEDSEL
                     KFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKCLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAYLTKAEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
     gene            6572..6959
                     /locus_tag="VLL59_001500"
                     /pseudo
     CDS             6572..6959
                     /locus_tag="VLL59_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370026.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            7083..8915
                     /gene="lepA"
                     /locus_tag="VLL59_001501"
     CDS             7083..8915
                     /gene="lepA"
                     /locus_tag="VLL59_001501"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HER6509617.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK"
     gene            9115..9692
                     /locus_tag="VLL59_001502"
                     /pseudo
     CDS             9115..9692
                     /locus_tag="VLL59_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528589.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
BASE COUNT         3171 a         1537 c         2089 g         2895 t
ORIGIN      
        1 taggagacaa aaatggataa gaaatactca ataggcttag atatcggcac aaatagcgtc
       61 ggatgggcgg tgatcactga tgattataaa gttccgtcta aaaagttcaa ggttctggga
      121 aatacagacc gccacagtat caaaaaaaat cttatagggg ctcttttatt tgacagtgga
      181 gagacagcgg aagcgactcg tctcaaacgg acagctcgta gaaggtatac acgtcggaag
      241 aatcgtattt gttatctaca ggagattttt tcaaatgaga tggcgaaagt agatgatagt
      301 ttctttcatc gacttgaaga gtcttttttg gtggaagaag acaagaagca tgaacgtcat
      361 cctatttttg gaaatatagt agatgaagtt gcttatcatg agaaatatcc aactatctat
      421 catctgcgaa aaaaattggc agattctact gataaagcgg atttgcgctt aatctatttg
      481 gccttagcgc atatgattaa gtttcgtggt cattttttga ttgagggaga tttaaatcct
      541 gataatagtg atgtggacaa actatttatc cagttggtac aaacctacaa tcaattattt
      601 gaagaaaacc ttattaacgc aagtagagta gatgctaaag cgattctttc tgcacgattg
      661 agtaaatcaa gacgattaga aaacctcatt gctcagctcc ccggtgagaa gagaaatggc
      721 ttgtttggga atctcattgc tttgtcattg ggattgaccc ctaattttaa atcaaatttt
      781 gatttggcag aagatgctaa attacagctt tcaaaagata cttacgatga tgatttagat
      841 aatttattgg cgcaaattgg agatcaatat gctgatttgt ttttggcagc taagaattta
      901 tcagatgcta ttttactttc agatatccta agagtaaata gtgaaataac taaggctccc
      961 ctatcagctt caatgattaa acgctacgat gaacatcatc aagacttgac tcttttaaaa
     1021 gctttagttc gacaacaact tccagaaaag tataaagaaa tcttttttga tcaatcaaaa
     1081 aacggatatg caggttatat tgatggggga gctagccaag aagaatttta taaatttatc
     1141 aaaccaattt tagaaaaaat ggatggtact gaggaattat tggcgaaact aaatcgtgaa
     1201 gatttgctgc gcaagcaacg gacctttgac aacggctcta ttccccatca aattcacttg
     1261 ggtgagctgc atgctatttt gagaagacaa gaagactttt atccattttt aaaagacaat
     1321 cgtgagaaga ttgaaaaaat cttgactttt cgaattcctt attatgttgg tccattggcg
     1381 cgtggcaata gtcgttttgc atggatgact cggaagtctg aagaaacaat taccccatgg
     1441 aattttgaag aagttgtcga taaaggtgct tcagctcaat catttattga acgcatgaca
     1501 aactttgata aaaatcttcc aaatgaaaaa gtactaccaa aacatagttt gctttatgag
     1561 tattttacgg tttataacga attgacaaag gtcaaatatg ttactgaggg aatgcgaaaa
     1621 ccagcatttc tttcaggtga acagaagaaa gccattgttg atttactctt caaaacaaat
     1681 cgaaaagtaa ccgttaagca attaaaagaa gattatttca aaaaaataga atgttttgat
     1741 agtgttgaaa tttcaggagt tgaagataga tttaatgctt cattaggcac ctaccatgat
     1801 ttgctaaaaa ttattaaaga taaagatttt ttggataatg aagaaaatga agatatctta
     1861 gaggatattg ttttaacatt gaccttattt gaagataggg agatgattga ggaaagactt
     1921 aaaacatatg ctcacctctt tgatgataag gtgatgaaac agcttaaacg tcgccgttat
     1981 actggttggg gacgtttgtc tcgaaaattg attaatggta ttagggataa gcaatctggc
     2041 aaaacaatat tagatttttt gaaatcagat ggttttgcca atcgcaattt tatgcagctg
     2101 atccatgatg atagtttgac atttaaagaa gacattcaaa aagcacaagt gtctggacaa
     2161 ggcgatagtt tacatgaaca tattgcaaat ttagctggta gccctgctat taaaaaaggt
     2221 attttacaga ctgtaaaagt tgttgatgaa ttggtcaaag taatggggcg gcataagcca
     2281 gaaaatatcg ttattgaaat ggcacgtgaa aatcagacaa ctcaaaaggg ccagaaaaat
     2341 tcgcgagagc gtatgaaacg aatcgaagaa ggaataaaag aactaggaag tgatattcta
     2401 aaggagtatc ctgttgaaaa cactcaatta caaaatgaaa agctctatct ctattatctc
     2461 caaaatggaa gagacatgta tgtggaccaa gaattagata ttaatcgttt aagtgattat
     2521 gatgtcgatc acattgttcc acaaagtttc attaaagacg attcaataga caataaggta
     2581 ctaacgcgtt ctgataaaaa tcgtggtaaa tcggataacg ttccaagtga agaagtagtc
     2641 aaaaagatga aaaactattg gagacaactt ctaaacgcca agttaatcac tcaacgtaag
     2701 tttgataatt taacaaaagc tgaacgtgga ggtttgagtg aacttgataa agctggtttt
     2761 atcaaacgcc aattggttga aactcgccaa atcactaagc atgtggcaca aattttggat
     2821 agtcgcatga atactaaata cgatgaaaat gataaactta ttcgagaggt tagagtgatt
     2881 accttaaaat ctaaattagt ttctgacttc cgaaaagatt tccaattcta taaagtacgt
     2941 gagattaaca attaccatca tgcccatgat gcgtatctta atgccgtcgt tggaactgct
     3001 ttgattaaga aatatccaaa acttgaatcg gagtttgtct atggtgatta taaagtttat
     3061 gatattcgta aaatgattgt taagtctgag caggaaatag gcaaagcgac cgcaaaatat
     3121 ttcttttatt ctaatatcat gaatttcttt aaaaccgaga taaagcttgt aaatggagaa
     3181 atttgtaaat gtcccctcat tgaatcaaat aaggaaactg gagaaattgt ctgggataaa
     3241 gggcgagatt ttgccacagt gcgcaaagta ttgtccatgc cccaagtcaa tattgtcaag
     3301 aaaacagaag tacagacagg cggattctcc aaggagtcaa ttttaccaaa aagaaattcg
     3361 gacaagctta ttgctcgtaa aaaagactgg gatccaaaaa aatatggtgg ttttgatagt
     3421 ccaacggtag cttattcagt cctagtggtt gctaaggtgg aaaaagggaa atcgaagaag
     3481 ttaaaatccg ttaaagagtt actagggatc acaattatgg aaagaagttc ctttgaaaaa
     3541 aatccgattg actttttaga agctaaagga tataaggaag ttagaaaaga cttaatcatt
     3601 aaactaccta aatatagtct ttttgagtta gaaaacggtc gtaaacggat gctggctagt
     3661 gccggagaat tacaaaaagg aaatgagctg gctctgccaa gcaaatatgt gaatttttta
     3721 tatttagcta gtcattatga aaagttgaag ggtagtccag aagataacga acaaaaacaa
     3781 ttgtttgtgg agcagcataa gcattattta gatgagatta ttgagcaaat cagtgaattt
     3841 tctaagtgtg ttattttagc agatgccaat ttagataaag ttcttagtgc atataacaaa
     3901 catagagaca aaccaatacg tgaacaagca gaaaatatta ttcatttatt tacgttgacg
     3961 aatcttggag ctcccgctgc ttttaaatat tttgatacaa caattgatcg taaacgatat
     4021 acgtctacaa aagaagtttt agatgccact cttatccatc aatccatcac tggtctttat
     4081 gaaacacgcg ttgatttgag tcagctagga ggtgactgat ggctggttgg cgtactgttg
     4141 tggtaaatac ccactcgaaa ttatcctata agaataatca tctgattttt aaggatgcct
     4201 ataaaacgga gctgatccat ttatcagaaa ttgatatttt gttattagaa acgaccgata
     4261 ttgtcttgtc cactatgctg gtaaaacgac tagtggatga gaatgtcctt gtcatattct
     4321 gtgatgataa acgattacca acagctatgc tgatgccttt ttatggtcgt catgattcga
     4381 gtttacagct tgggaaacaa atgtcctggt cagaaacagt caaatcgcag gtttggacga
     4441 cgattattgc tcaaaagatt ttgaatcaat cttgctatct aggagcatgc tcctattttg
     4501 aaaaatccca atctattatg gatttatatc atggtttgga aaattttgat ccgagtaatc
     4561 gagaagggca tgcagcgaga atttatttta atacactttt tgggaacgat ttctcaagag
     4621 atttggagca tccaatcaat gcaggtctgg attatggtta tactttatta ttgagtatgt
     4681 ttgcgcgtga agtggttgtg tctggatgta tgactcagtt tgggctcaaa cacgccaatc
     4741 agtttaatca gttcaatttt gctagcgata ttatggaacc atttaggcct ttggtggata
     4801 agattgttta tgaaaatcga aatcagcctt ttcccaaaat aaagagagag ttatttactt
     4861 tgttttcaga tacattttca tataatggta aagagatgta tctcacgaat attattagcg
     4921 attatactaa aaaagttgtc aaagctctga ataatgaagg gagaggagtt cctgaattta
     4981 ggatatgagt tatagatata tgaggatgat acttatgttt gatatgccga cggacaccga
     5041 tgaggaacga aaagcctatc gaaaatttcg gaaattttta cttagtgaag ggtttatcat
     5101 gcatcaattt tctatttata gtaagttgct gttgaataat acagctaaca atgccatgat
     5161 tggtcggctg agggagcata atcctaataa aggaaatatt actttattaa cagtcacgga
     5221 aaaacagttt gcacgaatga tttatttaca tggtgaaaga aataattgta ttgcaaactc
     5281 cgatgaaaga cttgtatttc ttggggaggc ttttgatgaa tcttaatttt tccttactag
     5341 atgaaccgat tccattaaga ggcggtacaa ttcttgtgct cgaagatgtc tgtgtatttt
     5401 caaaaatagt gcaatattgt taccaatatg aggaagattc tgaacttaaa ttttttgatc
     5461 acaagatgaa aacaatcaaa gaatcagaaa tcatgcttgt aacagatatt ttaggatttg
     5521 atgttaactc ctcaaccatt ttaaaattga ttcatgcaga tttagaatct caatttaatg
     5581 agaaacccga agtgaaatcg atgattgaca aattggttgc tacgattaca gaactgattg
     5641 tctttgaatg cttagaaaat gaattagatt tagagtatga tgaaattaca attctggaat
     5701 tgattaaatg tttaggagta aaagtagaaa cacaaagtga tactattttt gaaaaatgtc
     5761 tagaaatact tcaaattttc aaatatctca ctaagaaaaa gttgctcatt tttgtcaata
     5821 gtggagctta tctaacaaaa gctgaagtgg ctagtttaca agagtatata tcattgacaa
     5881 atttaacagt tctcttttta gaaccacgtg aactatatga ttttccgcag tatattttag
     5941 atgaagatta tttcttaata actaaaaata tggtataata ctcttaataa atgcagtaat
     6001 acaggggctt ttcaagactg aagtctagct gagacaaata gtgcgattac gaaatttttt
     6061 agacaaaaat agtctacgag gttttagagc tatgctgttt tgaatggtcc caaaacattc
     6121 tatcctcata ctttttccaa ggtgtagttt tagagctatg ctgttttgaa tggtcccaaa
     6181 accgctttag ctaatggcaa gcactcaatc atgttttaga gctatgctgt tttgaatggt
     6241 cccaaaactc gcattgctaa agtgaacaaa ggcagtgtgt tttagagcta tgctgctttg
     6301 aatggtccca aaacgacatc gaaccagtgc tttgctgcat aacagtttta gagctatgct
     6361 gttttgaatg gtcccaaaac cagatgtggt aaagatattt ttagcaaata gttttagagc
     6421 tatgttgttt tgaatggtct ccattcaaca ttgccgatga taacttgaga aagagggtta
     6481 ataccagcag tcggatacct ttctattctt tctgttaaag cgttttcatg ttataatagg
     6541 caaaaggaga aggagggtgg agtgatggat tatgattaag ccagatgggg ttaagcgagg
     6601 ggggagttgg agaggttttg cggcggattg aacgcctaag acttacgttt gagcgattcg
     6661 agctaagaca agctagttcg aaatatttgg ctaagcacga cgaggccttg gtgataaacc
     6721 ttttgatcct aaacttaaag cttacatgac aagtggtcct gttttaattg ggacacttct
     6781 tggggactaa ggtggttttg tctttttgaa ccatgatgag agtaaccaat cctacggatg
     6841 ctctttgcgg aaccattcgt gggaattttg ctcaggctcc tggtgatgat ggaggtattt
     6901 ttaacatggt gcatgggtct cattcaagag actctgctag gcgtgagatt gtcttttgat
     6961 ctcatcaaag taatcttggt agctccgcta ttctcttgca agataatccg taagaaaaga
     7021 taggcaaagg cctacctttt ttgttataat agaaggaaag actaaatgta taggaaaata
     7081 gaatgaacag tcaagattta aaaaaacgtc aggagaagat tcgtaatttc tccattattg
     7141 cacatattga ccatgggaaa tctactctcg ctgatcgcat tttggaaaag acagagacgg
     7201 tttcgtctcg tgaaatgcag gcccagttat tggactccat ggatttggag cgtgagcgtg
     7261 ggattaccat caagttaaac gccattgagc ttaattacac ggctaaagat ggggaaacct
     7321 acattttcca ccttattgat accccagggc atgtggactt tacttatgaa gtctcgcgtt
     7381 cgttggcagc ctgtgaggga gcgattttag ttgtggatgc agcgcagggt attgaagcac
     7441 agacccttgc caatgtttac ctagctcttg ataatgattt ggaaatttta ccggttatca
     7501 ataaaattga cttgcctgct gctgaccctg agagagtccg ccatgaagta gaagatgtca
     7561 ttggacttga tgcttctgag gctgttctgg cgtcagccaa ggctggtatt gggatcgaag
     7621 agattcttga gcaaattgtt gagaaggttc ctgctcctac gggtgatgtg gatgcgcctt
     7681 tacaggcctt gatttttgac tctgtgtatg atgcttaccg aggggtaatt ttgcaggttc
     7741 ggattgtgaa cggtattgtc aagcctggcg ataaaatcca gatgatgtct aatggaaaaa
     7801 cttttgatgt tacagaagtt gggattttca ctcctaaggc agttggacga gatttccttg
     7861 cgacgggaga tgttggttat gttgcggctt ctatcaaaac ggtagcagat acccgtgtgg
     7921 gggatacggt aactttagct aataaccctg ctaaggaagc cttgcatggc tacaaacaaa
     7981 tgaatccaat ggtctttgca gggatttatc cgattgaatc aaataaatac aatgacttgc
     8041 gtgaagcgct tgaaaaatta caactgaatg atgccagttt acagtttgaa cccgaaacgt
     8101 cacaagctct tggctttggt ttccgttgtg gatttttagg tttgcttcat atggacgtga
     8161 ttcaagaacg tttagagcgt gagtttaaca ttgatttgat catgacagca ccatctgtag
     8221 tctaccacgt tcacacaaca gatgaggaca tgattgaagt gtctaaccct tcagaatttc
     8281 cagacccaac ccgagtggct tttattgaag agccttatgt taaagcgcaa atcatggtgc
     8341 cacaagagtt cgtaggggct gttatggaat tatcgcagcg caagcgtggt gattttgtga
     8401 ccatggatta cattgatgat aaccgtgtca atgtgatcta ccaaatcccg ctggctgaaa
     8461 ttgtctttga tttctttgat aaattgaaat cctcaacgcg aggttatgcg agttttgatt
     8521 atgacatgtc agaatatcgc aggtcacaat tggtgaaaat ggacattctt ttgaacggtg
     8581 ataaggtcga tgcgctcagc tttattgttc ataaagaatt tgcttatgaa cgcgggaaaa
     8641 ttattgttga gaaattgaaa aaaatcattc cacgtcaaca gtttgaagtg ccgatccaag
     8701 ccgctattgg tcaaaaaatt gttgcgcgtt cagacatcaa ggcccttcgt aaaaacgttt
     8761 tggctaagtg ttatggtggt gacgtgtctc gtaaacgtaa attgctcgaa aaacaaaagg
     8821 ctggtaaaaa acggatgaag gctattggtt ctgtcgaagt ccctcaagaa gccttcttga
     8881 gtgttctttc aatggatgac gatgccaaga aataaccaag cttaaccgct tagtcttcag
     8941 aggagaactc ttgtgggtct acatgaccaa aaaattgatt atctcataaa aaaagaactt
     9001 tacaatctct ttcacataac actataatag tactatagac tatagtgtta tctcattatt
     9061 aggtgagcct gcatttaatc ttattaaaaa agagaaagag gaaacaaaaa ctgtgaacaa
     9121 aacaaaacaa aacaaaacaa aacaaaacaa aatagacttc tttgtcgcta tggcttaacc
     9181 tcagcggctg ctcttttgct gacctttgga ggtgcaagtg cagttaaggc ggatgtagta
     9241 ggaagacaac aagtgcaaga tgaacttcaa aatcagcgaa aagctttacc acgtcttaaa
     9301 gaattttata aggatactcc aaactccggt gttgaaaata ctccgattta taagtattta
     9361 actgaaatgg aagggaagtt aaatcgttat ctggagactt tagacgaagg gttgcaccag
     9421 ttgcaaggtg acaaaggtga agccggtccc gctggtccaa aaggccctgc aggtgaaaaa
     9481 ggtgagcgtg gtgagaccgg ccctgccggt cccgccggaa aagatggtga ggctggagcc
     9541 cagggtccaa tgggtcccgc tggcccacag ggtccacgtg gtgacaaggg cgaaactggt
     9601 gaaaaaggag aacaaggtcc cgccggaaaa gatggtgaac gtggtccagt aggtccagct
     9661 ggtaaggacg gccaaaacgg taaagatggt ct
//
LOCUS       DAUNLR010000057         9263 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUNLR010000057 DAUNLR010000000
VERSION     DAUNLR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9263
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.057"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(39..1352)
                     /locus_tag="VLL59_001503"
     CDS             complement(39..1352)
                     /locus_tag="VLL59_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HER6509618.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVALT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(1327..2286)
                     /gene="nrdF"
                     /locus_tag="VLL59_001504"
     CDS             complement(1327..2286)
                     /gene="nrdF"
                     /locus_tag="VLL59_001504"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HER6509619.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(2619..4778)
                     /gene="nrdE"
                     /locus_tag="VLL59_001505"
     CDS             complement(2619..4778)
                     /gene="nrdE"
                     /locus_tag="VLL59_001505"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HER6509620.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFITELAGIIKSENFHFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYADGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(4798..5016)
                     /locus_tag="VLL59_001506"
     CDS             complement(4798..5016)
                     /locus_tag="VLL59_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HER6509621.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            5409..5672
                     /locus_tag="VLL59_001507"
     CDS             5409..5672
                     /locus_tag="VLL59_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HER6509622.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            5677..7410
                     /gene="ptsP"
                     /locus_tag="VLL59_001508"
     CDS             5677..7410
                     /gene="ptsP"
                     /locus_tag="VLL59_001508"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HER6509623.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            7595..9022
                     /locus_tag="VLL59_001509"
     CDS             7595..9022
                     /locus_tag="VLL59_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HER6509624.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALISGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLVLAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            9117..>9263
                     /locus_tag="VLL59_001510"
     CDS             9117..>9263
                     /locus_tag="VLL59_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deacetylase"
                     /protein_id="HER6509625.1"
                     /translation="MKKLNVILVGLLSILMLSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSDLV"
BASE COUNT         2959 a         1648 c         1944 g         2712 t
ORIGIN      
        1 ttcatccgaa gctttttatt aaaaaagtaa ttaactaatc atttaaggat gaaacgataa
       61 aactgatagc taaaataaaa aatgaggtta gctaatgcta aagggataat cattagtaac
      121 gattggcctg taatttcaac cagaaaaact ggtgccgcca agggtatctt attgatcaca
      181 cctaaaaaga ttgttgcacc aaccataatg gctaacgtat ttgatagaga caagggaata
      241 aggtactgac taaggatagc tagtagtaag ccactagcac ctccaagcat catagaagga
      301 gcaattttac ccccttttgc tccagaagca aaaactaaag agatagcgac agctttggca
      361 acaagtagcc agctaatata gctcagatgt ggttcttcgt ggagaaaaaa gagtaatcca
      421 gctttgccat ttcctaaaat ctctgggaag aaaatgctga gtcctgcgat aaggctaaaa
      481 gcgatgagaa ctttcggaat aaaccactga cttttggcat cagccttagg aaggtgttcc
      541 aaaagatgtt tgtaagcgtg agcaaagagg gaaaggataa gaccagccag gacggaccaa
      601 ataagggttc ctagcgtcca atgttgctga ggcattaggt attgaatctc atgtcggcct
      661 tgtaataaag caactgtttc cacagccaca tagctcgtta ggcaggcagc gtatatattt
      721 ttaagggacc aacggttaag aatagcttcc aagataaata aaatagtggc taagggagca
      781 ttgtagacag caccaagggc agcgccagaa gcgcaagcta ataaaagttt ttgatcggct
      841 tttgacaagt tacatctttg gctccaaaga gacgtcaagg caacagcgac ttcccgtgaa
      901 gctccttctc ggccgacagg agctcccata gatacggtcg ttaattggag ccaaccatgc
      961 caaaactgtg tccagggact aaatgagatg tcatcttgaa tgatttgctg aatagattga
     1021 atgtcctttc cttttttagc caataggtgc cacccaagac ctgcaagaag tccagcaaag
     1081 aggagtgaaa gagctcgtct ttgtggtgga acactagcaa tcatagtgct aaaagaacct
     1141 tgactgaatc caaaactgag ggactgaatc aggtgaatgg cttttgttaa gataaaagca
     1201 acaaggccag ctgttaaacc tgttaaaaag aggtaaaagg tcaagagtaa aaagtgtcgt
     1261 ttcataagac tattataaca aaagttaaga aaagagactg atagattatc agtctcgtga
     1321 gcactattag agtccataat tataatcgtc atcagacata gcttctacag aaccaagaag
     1381 atagccattc cctacctgtg agaaaaagtc atggtttgat gttcctgttg aaataccatt
     1441 cataacaatt gggttaacat cgtttgcagt atctgggaat aaaggatctt gtcctaaatt
     1501 cataagagct ttgttagcat tgtagcgtaa aaaggtcata acttcctcag tccaccccac
     1561 gccatcataa agcgttttgg tgtatttttc ttcattttca tacagctgat aaaggaggtc
     1621 atacatccaa tcacgaaaat tctcttgctc atcttctggt agttcgttaa aaccaagctg
     1681 gaatttgtaa ccgatataag taccatgtac agattcatca cgaataatta gtttaatgat
     1741 ttcagcaaca tttgctagct tattatttcc caaatagtaa agaggggtga aaaagccaga
     1801 ataaaaaagg aaagtttcga gatatgttga ggcaactttc ttttgtaagg catctccatt
     1861 agcgtaaatg tcattgataa tacgtgcttt ttcttgaaga aactcattat tattagtcca
     1921 ctcaaagatc tcttcaattt ctttttttgt gtttaaggtt gaaaagatag acgaataaga
     1981 tttagcgtga actgattcca tgaattgaat attgtttaag acagcttctt cgtgaggagt
     2041 gcgaacatca gcacgaatag cttcgacacc agtttctgat tgcatggtat caagtagggt
     2101 taatcctcca aaaaccttgc caacaagatc tttttcttga agagaaagtt tgcgccaatc
     2161 gtctaagtca tttgataaag ggatacgggt atcaagccaa aattgttcgg tcaacttttc
     2221 ccaagttgac ttgtcaatga cgtcttcgat ttcattccag ttaattgctt cataatatgt
     2281 agtcatagaa aaatgatctc ctaaagagta gtaaagtgcg ttaaggatat cgagataaac
     2341 cagtagaacc gaccaaagtt ctaacggtaa taataagttt aaatagattc aaaagggtaa
     2401 cgaatgagtt agtgagtggt ttaggcggaa cgcctaaagc gattgcccaa gaagtaatag
     2461 atgctttagc atcattaggg catatcgagg aattacgaca cggagtaagg aaagtcgata
     2521 atactttcct tacgtagtta gtgagtggtt taggcagatc gcctaaagcg actgccgtag
     2581 aagtaataga tgctttagca tcattacttc ttaaccaatt aaatgacaca agattcacat
     2641 tggtttgcgc ccacttcttc cccatcatcc gtaaaggtac ggatatagta gatagattta
     2701 atgcctttat tgaaagcgta gtttcgtaag atggataaat cacgagtggt ttgtttgctt
     2761 tgtgttttcc actcataaag ctccataggc aactcactac gaaggaatag agttaatgac
     2821 aagccttggt ccacatgttc ggtcgcagcg gcatagacat caataacttt gcgcatgtcc
     2881 atatcgtaag cagatgtata gtaaggaatg gtatccgtag acaaaccatt tgcaggatag
     2941 tagattttac caattttctt ttcttgacgc tcttcgatgc gttgtgtgat tgggtgaata
     3001 gaagcagagc agtcattgat ataagaaata gagccatttg gagcaactgc tagtcggttt
     3061 tgatgataaa gaccatcttt ttgaacggcg tcgcgaagag cctcccaatc tgaagcttgc
     3121 ggaataaaat ggtctttaaa gagacttttg accaaatcag attttggaac aaagtgtcct
     3181 gtaacgtatt tatcaaagta actaccatca gcgtacttag agttctcaaa gccaacaaag
     3241 gtagtttggc gctcacgagc gatgttattg gattcgacca aggtccaata attcaggagc
     3301 ataaagtaaa tatcagtaaa ctcgatggat tctggactgc catattcaat atgatgttga
     3361 gcaaggtaag aatgtagtcc catagctcca aggccaaaag tatgtgcttg actgttacca
     3421 tgtttaatgg ttggaacagc ttcaatgctt gatgaatcag taacaaaagt tagggcacgt
     3481 gtcatagtct taatagaacg gccaaagtct ggtgaggtca tcatgttcag gatattagtg
     3541 gaacctaagt tacatgaaat atcagttccc atttctacaa actcttgcgc atcattgata
     3601 aggctaggtg tttgaacttg taaaatttca gaacacaagt tgctcatgat gatttttcca
     3661 tcgataggat tagctttatt agctgtatca atattgatga tataagggta accagattct
     3721 tgttgtaatt ttgaaatctc tgtttcaaga tcacgagctt taattttagt cttagtaatt
     3781 ttagggttcg ccactaactc atcgtacata ttggtaatgt cgagatagtt aaagggaatg
     3841 ccatattctt tttcaacatt gtaaggacta aagagataca tgtcctcgtt tttacgagct
     3901 aattcgtaga atttatcagg aacggtaatc cctagtgaca aggttttaac acgcaccttt
     3961 tcatcggcat tttctttttt agtagataag aaagcaatga tatcaggatg aaaaacattt
     4021 aggtaaacaa caccagctcc ttgacgttgc ccaagttgat ttgaataaga aaaactatct
     4081 tcaaataatt tcataacagg aacaactcct gaggctgcac cagcatagcc tttgattggt
     4141 gcgccagctt cacggaggtt agacaaggta atcccaactc ctccaccaat acgggataat
     4201 tgcaaggcag agttaatgga acgtccgata gagttcatgt catcagttac ttgaatcaag
     4261 aaacaagaga ccaattcacc acgacggctt cgaccagcat ttaaaaagga aggagtagcc
     4321 ggttggtaac gttggttaat catttcaacg gctaaatctt ttgctaagtc ttcttgacca
     4381 tctgcaaaat acaaagcatt aaacaagaca cggtcttcaa ggttttctaa ataatgctct
     4441 ccatcatttg tttttaaggc gtattgctgg tagaacttgt aggctgccat aaatgattta
     4501 aagtgaaaat tttctgattt gattatgcca gctaattcag taataaattc agggtggtat
     4561 ttctgaataa aagctgattc aatgtaatca tttgagatta aatactcaat tttttccgta
     4621 atggaagtaa aagacatggt gtttggcagc acattttcag cgaaaaaagc ttttaaagct
     4681 tctttgtctt tatgaagtgg aattttacca ttaacaggac ggttaatttc attatttagg
     4741 cgaaaatatg aaatatcgcc aagatctttg agactcatat tatttttcct tgtcttatta
     4801 aatcaattct tttaactttg caggttggaa gccagaaaat acgaggttgt ctgcttcgat
     4861 aacaggagca gatgtgaagc caagactttt cacataatcc actttttcag gatgttcatc
     4921 gatattaatt tcctggaagt tggctccgtg ttgttctaag aatttcttag tcattttgca
     4981 ctgcatgcaa ttatttttgg aatatactgt aatcatgtct tgtccttcta aaattagtaa
     5041 tggttccatc ttaaatggaa ttactataat agcatataaa aaataaagct aaaaagcaag
     5101 ctataaactt atctaaaaca caacatattg tgttgaaata aaaaacagaa acctaaatat
     5161 tgtgtcaatc tggattctta tggttagagc tctagcgttt tgatgataga agataagcag
     5221 ttttaataaa gcattaaagt ctgaaaaata aattgtgaaa aacgtgaaaa taaaagaaaa
     5281 taatttcaca ttttttgtcg tttaaatatt taatcttgaa aataaaaaag cattgtgcta
     5341 taatcggttg ttgtaagggt tatcatgtga tggctcaaaa atacacaact taaaaggaga
     5401 accatactat ggcttcaaaa gactttcaca ttgttgcaga aacaggtatt catgcgcgtc
     5461 cagcgacttt gcttgttcaa acagctagca aatttgcttc agacatcact cttgactaca
     5521 aaggtaaagc agtaaatcta aaatcaatca tgggtgttat gagtcttggt gttggtcaag
     5581 gtgcagatgt tactatctca gctgaaggtg cagatgctga agatgccatt gcagcaattg
     5641 aagaaacaat gactaaagag ggattggcat aagactatga cagaaatgct taaaggaatt
     5701 gcagcctcag acggcgttgc tgttgctaaa gcatatctac tagttcagcc ggatttgtca
     5761 tttgagactg ttacagtcgc agatacaaat gcagaagaag ctcgccttga tgttgcactc
     5821 caagctgcac aagacgagct ttctgttatc cgtgaaaatg cagtagaaag cttaggtgaa
     5881 gaagcagcag ccgtttttga tgcccatttg atggttcttg ctgatccaga aatgatcagc
     5941 caggttaaag aaacgattcg cgcaaaacaa acgaatgcag aaacaggtct taaagaagtg
     6001 actgacatgt tcatcaccat ctttgaaggc atggaagata acccatacat gcaagaacgt
     6061 gcagcggaca tccgcgacgt tgcaaagcgt gtgttggctc accttttagg tgtaaaactt
     6121 ccaaatccag ctacaatcaa tgaagaatca atcgttatcg cacacgattt gacaccttca
     6181 gatactgctc aacttaacaa acaatttgta aaagcatttg ttacaaatat cggtggtcgt
     6241 acaagtcact cagctatcat ggcacgtaca cttgagatcg ctgcggtact tggaacaaat
     6301 gatattacaa aacgtgttaa agatggtgat gtgattgccg ttaatggtat cactggtgaa
     6361 gtgattatcg atccaagcga agatcaagta cttgctttta aagaagctgg tgcggcttat
     6421 gccaaacaaa aagcagagtg gtctctcctt aaagatgcgc acactgaaac agctgatggc
     6481 aaacactttg aattggctgc taatatcggt acgcctaaag acgttgaagg tgttaatgac
     6541 aatggcgctg aagctgttgg cctttaccgt actgagttct tgtacatgga ttctcaagac
     6601 ttcccaactg aagacgaaca atacgaagct tacaaagcag tgcttgaagg catgaatggc
     6661 aaacctgttg tggttcgtac aatggatatt ggtggagata aggaacttcc ttactttgac
     6721 cttccaaaag aaatgaaccc attcctcggt ttccgtgctc ttcgtatctc aatctctgaa
     6781 actggggatg ccatgttccg cacacaaatg cgtgcgcttc ttcgcgcctc tgttcacgga
     6841 caacttcgta tcatgttccc aatggtagca cttcttaaag aattccgtgc tgcaaaagca
     6901 gtctttgacg aagaaaaagc aaacttgctt gcagaaggcg ttgcggttgc tgatgacatc
     6961 caagttggta tcatgattga gattcctgca gctgctatgc ttgcagacca atttgctaag
     7021 gaagttgatt tcttctcaat tggaacaaac gaccttatcc aatacactat ggcagcagac
     7081 cgtatgaacg aacaagtatc atacctttac caaccataca acccatcaat attacgtttg
     7141 atcaacaatg tgatcaaagc agcgcacgct gaaggtaaat gggcaggtat gtgtggtgag
     7201 atggcaggtg accaacaagc tgttccactt cttgttggaa tgggcttgga tgagttttct
     7261 atgtcagcaa cttcagtact tcgtacgcgt agtttaatga agaaacttga ctctgctaag
     7321 atggaagaat atgcaaatcg tgcgcttaca gaatgttcaa cagcagaaga agttcttgaa
     7381 ctttctaaag aatacgtttc tgaagattaa cgggttaaag agttggttta aaccagctct
     7441 tttttgctag ctaaaaatac aattactttt tggtgtgaaa tcatttgagt tatcaaataa
     7501 ttatcagaat tttcagatat ttagtgtagc caaatcttga attatatcgg aaaagtgata
     7561 gaataagatt actatcataa aaggagataa aacgttggca aaacaatata aaaatttagt
     7621 gaacggtgaa tggaaactat cagaaaacga gattaccatt tacgcaccag caacaggtga
     7681 agagttagga tcagttccag cgatgacgca ggcagaggta gatgctgttt acgcttcagc
     7741 taaaaaggct ctatcagatt ggcgcgcctt gtcttatgtg gaacgtgcag cttaccttca
     7801 taaagcggct gatattttag tacgtgatgc tgaaaagatc ggcgcgattc tttcaaaaga
     7861 agtagccaaa ggtcacaagg cagctgtcag tgaagttatt cgtaccgctg aaatcattaa
     7921 ttatgcagca gaagaagggc ttcgtatgga aggtgaagtt cttgaaggtg gtagcttcga
     7981 agccgcaagt aagaagaaga ttgctattgt tcgtcgtgaa ccagttggtt tagttcttgc
     8041 catctcacct tttaattatc ccgttaactt ggcaggttct aaaattgctc cagcccttat
     8101 ttcaggaaat gttgttgctc ttaaaccacc aacacaaggc tctatttctg gtttgttact
     8161 agcagaagct tttgcagaag ctggtattcc agcaggtgtc tttaatacca ttacagggcg
     8221 aggttctgtt attggggatt acatcgttga gcatgaagcg gttaacttta tcaactttac
     8281 aggttctact ccaattgggg aaggaatcgg taaattagcg ggtatgcgac caattatgct
     8341 tgagcttggc ggtaaggatt ctgctatcgt tttggaagat gcagatcttg ttttagcagc
     8401 gaaaaatatt gtagccggtg cttttggtta ctcaggacaa cgttgtacag cggttaaacg
     8461 cgttcttgtg atggacaagg tggcggatca attggcggct gagattaaaa cacttgttga
     8521 aaaactaagt gtcggaatgc ctgaagacga tgctgatatt acaccattaa ttgatacatc
     8581 agctgctgat tttgttgaag ggttgattaa agatgcaact gataagggag ctactgcttt
     8641 gacagccttt aatcgtgaag gcaatcttat ttcacccgtt ctctttgatc atgtgacaac
     8701 tgacatgcgt ttggcatggg aagagccgtt cggcccagta ttaccaatta ttcgtgtaac
     8761 cactgtagaa gaagccatca agatttctaa tgagtctgaa tatggtttgc aagcttctat
     8821 ttttacaact aatttcccaa aagcttttgg cattgctgag caattagaag ttggaactgt
     8881 tcaccttaac aataaaacac aacgtggaac agataatttc ccattcttag gcgctaaaaa
     8941 atcaggtgca ggggtacaag gagttaaata ttctatcgaa gctatgacaa ctgttaaatc
     9001 tgttgtattt gatatccagt aataaaaaaa ataaacaaaa agttaggtta acttaacttt
     9061 ttgtttattt ttttaatgtt ttttgttaca atagtctata cagatggagg caactattga
     9121 aaaaattaaa tgttattctt gttggtttat taagcattct gatgttgagt ttagctattg
     9181 tgtttattaa tcgttggaaa ctaaacgaag atagtcagcg tatagttttg gctgaaaaga
     9241 aaaaaaacac gtcagattta gtg
//
LOCUS       DAUNLR010000058         9119 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUNLR010000058 DAUNLR010000000
VERSION     DAUNLR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9119
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.058"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            22..477
                     /locus_tag="VLL59_001511"
     CDS             22..477
                     /locus_tag="VLL59_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HER6509626.1"
                     /translation="MIIDLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKR
                     ANSTKGLSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWGQL
                     GLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKLEAPQVDLKQKEEE"
     gene            595..1347
                     /locus_tag="VLL59_001512"
     CDS             595..1347
                     /locus_tag="VLL59_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HER6509627.1"
                     /translation="MATLDEVLSFAKGLADAGQGVDLDNVYGTQCVDLPNWITTKYFG
                     IALWGNAIDLLDSAAAQGMEVVYNAPGVNPRAGAIFVMVTYAHGYGHTGLVIVTSDGY
                     VLHNIEQNVDGNADALYIGGPARYVDRPFEDGTGYILGWFYPPYDSTPAAVTEPSAPV
                     VAQLDGTYVANPETGTFTVRVAALNVRSAPRLDAEIVATYGENMEFNYDGWIDSDGYI
                     WVTYISVTGVRRYVYVGNSENGRRVTNFGTFR"
     gene            complement(1436..1792)
                     /locus_tag="VLL59_001513"
     CDS             complement(1436..1792)
                     /locus_tag="VLL59_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509628.1"
                     /translation="MTKTTAQRKKSIYINGALEKVYDECSNGMRNRTFSGRVMDIAER
                     YDALMGLTEIPELTPQQQMILGEAVLGAFMDRNKIRYLHDAIADTEIDGCLDLAKMVR
                     DLDYAQRLKLIESINI"
     gene            complement(1856..2095)
                     /locus_tag="VLL59_001514"
     CDS             complement(1856..2095)
                     /locus_tag="VLL59_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509629.1"
                     /translation="MKYFTTDIENIENITIFEEFGFDFEESEDGTWYTEDKAMFDWWN
                     ELAQAIEFLNDNGIDAETNELADYVTVAKENGFEF"
     gene            2369..3787
                     /locus_tag="VLL59_001515"
     CDS             2369..3787
                     /locus_tag="VLL59_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HER6509630.1"
                     /translation="MDKKIQRFSCTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMI
                     VVKSEDQPRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATE
                     TITTNSRVLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVA
                     FSDEHDIWWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFI
                     DTYHLDLTYSHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWC
                     QKPYRKITVEDVKYVLSSHYQDTGYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRP
                     NKPQEIAAIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAAL
                     ADPHYNHHETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQ
                     TLLNKILFDASNLMTNRFSLSD"
     gene            3939..5486
                     /locus_tag="VLL59_001516"
     CDS             3939..5486
                     /locus_tag="VLL59_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HER6509631.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            5633..6355
                     /locus_tag="VLL59_001517"
     CDS             5633..6355
                     /locus_tag="VLL59_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HER6509632.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKMGKMPKTEILS
                     FEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEAGLLGIKKGDPVLHIIRKTYNDKNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            6374..7573
                     /locus_tag="VLL59_001518"
     CDS             6374..7573
                     /locus_tag="VLL59_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HER6509633.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCNSANRNNVHVIFTGAGTSEYIGNTICPYLKNVGNRQRYLFESVASTDLVAAP
                     DYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKTLALLQGGDINFSEDQFRL
                     DTRHLLPDAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(7670..7930)
                     /locus_tag="VLL59_001519"
     CDS             complement(7670..7930)
                     /locus_tag="VLL59_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HER6509634.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(8045..8986)
                     /locus_tag="VLL59_001520"
     CDS             complement(8045..8986)
                     /locus_tag="VLL59_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HER6509635.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGKCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LISQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
BASE COUNT         2760 a         1736 c         1896 g         2727 t
ORIGIN      
        1 aagcaggatt gaggtggtta gatgattatt gatttaacaa gtcttattca ccttttcggg
       61 gatttagttc gtaccgtcga aatccacgtt tttacacttt ttgtctgttt tgacattatc
      121 acaggactga caaaaggtat tactaataag agagcaaaca gtacaaaagg gctatctggc
      181 attattaaac actttttagt tgtgttgtta gtctatactg tctatcctta cctaatcttg
      241 ctcggagcta agcctttagc agtcgccttt gtcctatttt ttatcgcctg ttatggtatt
      301 tcaatcgtag aaaattgggg acaactaggt ttgccaatgc caagttttgt cagatcattt
      361 ttcgaaaagc tcaaacgtga tacagaccag tttgatattg cgacaatcaa aattgataaa
      421 acaggtgtta aactcgaggc gccacaagtt gatttaaaac aaaaagaaga ggagtagcat
      481 gagacaagca gtcacacgat tagcattagt tatagcaatc gcaatactgt atgtgccatt
      541 atctgtggtt gctttgattt taagcccatt ttttgaagaa aggaagtaac tgatatggca
      601 actttagacg aagtcttgtc ttttgcaaaa ggattagcgg atgctggcca aggagttgat
      661 cttgataatg tttacggtac gcagtgcgtg gacttgccaa actggatcac gacaaaatat
      721 tttggcattg ccctttgggg caatgctatt gacttactag atagtgcagc tgcccaagga
      781 atggaagtgg tctataatgc tcctggagtt aatccacgag ctggggctat ctttgtgatg
      841 gtgacctatg ctcatggtta cggtcatact ggattagtta ttgtgacgtc agacggatat
      901 gttctgcata acatcgagca aaacgtggat ggtaatgctg acgcccttta catcggtggt
      961 ccagctcgat atgttgaccg cccatttgaa gatggcactg gatatatttt gggttggttt
     1021 taccctcctt acgatagtac gccagcagca gtgacagagc caagcgctcc agtggttgca
     1081 cagttagatg gtacttatgt agctaaccct gaaacaggta cttttactgt tcgtgttgct
     1141 gctttaaacg tccgttctgc gcctcgtcta gatgcagaaa ttgtggcaac ttatggcgaa
     1201 aacatggaat ttaactatga tggttggatt gactcagatg gttatatttg ggtgacatac
     1261 atcagtgtta ctggtgttag acgatatgtg tacgtcggaa attccgaaaa cggacgacgt
     1321 gtgaccaact ttggtacttt tagataggag gtaaagctcc gagataagac aaaaccgctc
     1381 agattaattt ctgggcggtt ttttgtgtgt ctaaaaaagc agcaatgtta gccgctcaaa
     1441 tattaatcga ctctattaat tttaggcgct gtgcgtaatc taaatctcta accatcttgg
     1501 ctaaatccag acagccgtca atctctgtgt cggcaatagc atcgtgcaaa tatctgattt
     1561 tattgcgatc cataaaagca ccgagaacag cctcgcctaa aatcatttgc tgctgtggtg
     1621 tcaactctgg aatctctgtt agccccatta gagcatcata gcgctctgca atatccatga
     1681 cgcgaccact aaacgtacga ttgcgcatgc cgttgctaca ttcatcataa accttttcta
     1741 gtgcgccgtt aatataaatt gattttttgc gttgtgctgt tgtttttgtc attttatcct
     1801 tcctttggta catatttttc aattagtttt agacgataat tataagcttc cttaattaaa
     1861 attcaaatcc gttttcttta gcaactgtta cgtagtccgc tagttcattg gtttctgcat
     1921 caatcccgtt atcgtttaaa aattcgattg cttgagcaag ttcattccac cagtcaaaca
     1981 tcgctttatc ttctgtatac caagttccgt cttctgattc ttcaaagtca aaaccaaact
     2041 cttcaaagat tgtgatgttt tcaatatttt cgatgtcagt tgtaaagtat ttcatatttt
     2101 cctcctcggc ctctttcagg ccttgcgatt tattttttgt aagcctttgt cttacttaca
     2161 tacttattat aacatcaggt agcacccaag tcaatacctt tcttaaactt ttttaaaaaa
     2221 tattccatta aacaagacca aaacaaaaaa gtccttttta taagactttt tccgaataat
     2281 aagataagga ggtgctgctg gaattatgaa tttttgtatc cagttcaatg gatatttgat
     2341 ataatcgtct taaaaaggag gtcgtgaaat ggataaaaaa atacagcgtt tttcatgtac
     2401 aactatactc gtcggtaaaa aggcatctta tgatggctca accatggttg ctcgaacaga
     2461 agattctcaa aatggagatt tcacgcctaa aaaaatgatt gtggtgaaat cagaagatca
     2521 accgagacat taccgttcgg tgcaatcttc ctttgagatg gacttaccgg acaatcccat
     2581 gacttacacg tctgttcccg atgcgcttgg taaagatggt atctgggcag aagcaggcgt
     2641 gaacgaggct aatgtggcca tgtcagcaac tgaaaccatc actaccaatt ctcgtgtttt
     2701 aggggcagat cctctagtag cttctggtat tggtgaggag gacatggtga ccttagtgct
     2761 cccttatatc cgttctgcgc gtgaaggggt tttgcgcctt ggtgctattt tagaagacta
     2821 tggcacttac gagtcaaatg gtgtggcttt ttcagatgaa catgacattt ggtggctgga
     2881 aacgattggt ggtcatcact ggattgcaag acgggtgcca gatgatgctt atgtcaccaa
     2941 tcccaatcaa tttggcattg atcattttga atttaacaat cctgaagatt acctttgctc
     3001 agctgattta aaggacttta ttgacacgta tcacttagat ttaacctata gccatgagca
     3061 ttttaatccg cgctatgctt ttggtagtca acgtgacaaa gaccgtcact ataatacgcc
     3121 acgtgcttgg atcatgcaaa aattcttaaa cccagaaatt gtgcaagacc cgcgcagctt
     3181 tgcccttgct tggtgtcaaa aaccttaccg taaaataaca gtagaagatg tcaaatatgt
     3241 attgagtagt cactatcagg acacgggtta tgacccttac ggttcagaag gaactcctgt
     3301 tagtaagaaa gtctttcgcc ctattggcat taaccgtacc agccaaaccg ctatcttaca
     3361 cattcgtcct aataaacctc aagaaattgc cgctattcaa tggatggctt atgggtcaat
     3421 gccatttaat accatggtgc cttttttcac acaggtgaag actattccag attattttgc
     3481 caacacttac gaaaatgtgt ctaccgacaa tttctattgg accaaccgtc tgattgcggc
     3541 tttggcagat cctcactaca atcatcatga aactgatttg gacaattact tggaagaaac
     3601 catggcaaaa ggtcatgcca tgttacatgc tgtggaagca cagttattgg ctggtgaaac
     3661 agtcgatttg gaagaggaaa atcaaaaaat gagtgactat gtgcaaggag aaacgcagac
     3721 gctattgaac aagattctct ttgacgctag caatctaatg actaatcgtt tcagtttgag
     3781 cgattaaaag tgaagctaag gctgagcaac tgcttagcct tttttacgat aactttttag
     3841 gaaaagtaat cgcaaaaaga caaaaacttg gaaaaaaaat caaagtatgt tatacttaac
     3901 tggtcaattt ttaaccagtt aataacaaag gaggaatcat gaaaaagaaa attcttttaa
     3961 tgatgagttt aatcagtgtc ttttttgctt ggcaacttac tcaggcaaaa caagtcttag
     4021 cagagggtaa agtgaaggtg gtgacaactt tctatcctgt ttatgaattt acaaaagggg
     4081 ttattggtaa tgatggcgat gtttccatgc ttatgaaagc aggaacggaa cctcatgatt
     4141 ttgagccttc tacaaaagac attaaaaaaa tccaagatgc agatgcattt gtttatatgg
     4201 atgacaatat ggaaacttgg gtttctgatg tgaaaaaatc attgacatct aaaaaagtga
     4261 ccatcgtcaa gggaactggt aacatgctct tggtagcagg agctggacat gaccatcacc
     4321 atgaggatgc tgacaaaaag catgagcata ataaacatag cgaagaagga cacaaccatg
     4381 cttttgaccc acacgtgtgg ttgtcaccat accgtagcat tacagtcgtt gaaaatattc
     4441 gcgacagtct ttcaaaagct tacccggaaa aagcagagaa cttcaaagcc aatgccgcta
     4501 cttatattga aaaattaaaa gagcttgaca aagactatac ggcagcactt tcagatgcta
     4561 agcaaaagag ctttgtgaca caacacgcag cttttggtta tatggcactt gactatggct
     4621 tgaaccaaat ttctattaat ggtgtcacac cagatgcaga accatcagca aaacgtattg
     4681 ctactttgtc aaaatacgtt aaaaaatatg gcatcaaata catttatttt gaggaaaatg
     4741 cgtcaagtaa agtcgcaaaa accctagcta aagaagcagg agttaaagcg gctgtgctta
     4801 gtccgcttga aggtttgact gaaaaagaga tgaaagctgg ccaagattac tttacggtca
     4861 tgcgtaaaaa ccttgaaacc ttacgcttaa ccactgatgt ggctggtaaa gaaattcttc
     4921 cagaaaaaga cacgactaag acagtttaca atggttattt caaagacaaa gaagtcaaag
     4981 atcgtcaatt atctgactgg tcaggtagct ggcaatctgt ttacccctat ctacaagatg
     5041 gtactttaga ccaagtttgg gactacaagg ctaaaaaatc taaaggtaaa atgacagcag
     5101 ccgagtacaa agattactac actactggtt ataaaactga cgtggaacaa atcaaaatca
     5161 atggtaagaa aaagaccatg acctttgttc gtaatggtga aaagaaaacc ttcacttaca
     5221 catacgccgg caaagaaatc ttgacctatc caaaaggaaa tcgtggagtt cgtttcatgt
     5281 ttgaagctaa agaaccaaat gctggcgaat tcaaatacgt tcaatttagt gaccatgcca
     5341 ttgctcctga aaaagcagag catttccacc tgtactgggg tggtgacagc caagaaaaat
     5401 tacataaaga gttagaacat tggccaactt actacggttc agacttatct ggtcgtgaaa
     5461 ttgcccaaga aatcaatgct cattaatctt aactcactaa gcaaatcttc ttttaaggag
     5521 gtttgctttt tctttgtgga gtaaaaaaat taataattct caacattaat ttgacgggca
     5581 cttatgatta taatatactt taagtggtta taacaagtta gaggtgaata agatgccaaa
     5641 agaacaacca ctctatctac agattgttga tgacttggaa gtgaaaatca aaaaaagcat
     5701 gacagaaaac gataagttgt tgtcagaacg agaattaagc gacctttacg gtgttagtcg
     5761 tatcacgatt agactggctc ttaaggaatt ggaattacga gacttaattt ataaaaagca
     5821 gggcaagggg acttatgttt caggaatcaa agaacctgtc actgatttat caagtacata
     5881 tagctttaca gagcagatga aaaaaatggg aaaaatgcct aaaacagaaa ttctttcctt
     5941 tgaacagtat caggtaacac cttacttgtc tggtctctta gagcttgatc ccgatacaga
     6001 agtttttgaa ttagaacgcc taaggattgc agatgatatg cccttgatgt ttgaacgatc
     6061 ctatattcct gctcagcctt ttcaggggtt aagcattgcg gacttgaagc gtaaagcttt
     6121 gtacgatatc tttgcaaagg actatcaaga gacaatccgt cttgcagaag aagagtttta
     6181 tgccagcatt gccttggact atgaagcagg tctcttaggc attaaaaagg gagatcctgt
     6241 cttacatatt attcgtaaaa cttataatga taaaaatatc ttaattgaat tgactttcag
     6301 cattgcaagg gcggatcagt ttaggtaccg ggtgcaacat caccctaatg gttaaggaat
     6361 tggaggttag gacatgttta caaaaacgca ggaagctttg gaggctcttg gtgcagctat
     6421 cactaccaag gaaattaaac aagaaccccg tttatggcaa gaaaccatga cgttttttga
     6481 agaaacaaga gattctctgg attctttttt aaagagagtt tgtaacagcg ctaacagaaa
     6541 taacgttcat gtcatcttta caggtgcggg tacatctgag tacatcggta ataccatttg
     6601 cccttacttg aagaatgtgg ggaatcggca gcgctatctc tttgagagcg ttgcttcaac
     6661 cgatttggtt gcggcgccag attattatct tgttgaggaa gagacggtac tattagtctc
     6721 ctttgctagg agtggtaata gtccagaaag tgtagcggct gttaacctgg tcaatcaact
     6781 agtgccaaat agttatcatt taaccattac ctgcgccaaa gatggagaac tggcgaaaaa
     6841 agcacagcaa gatgagcgtt cttaccttta tttgatgcct gaagacgcta atgatgctgg
     6901 ttttgccatg actggtagtt ttacctgtat gatgctagcg gctcttttga tttttgatga
     6961 tgctaacagt atagctcaga aagaagctta tgtgactgat atgattcttg ctgggcaagc
     7021 tgttattgac caagaaagac ggctacaaga gctagctgat ttaggatttg aacgtttagt
     7081 ttatctaggt tctgctggtt tagccaagtt aacccaagaa gctcaattaa aaatgttaga
     7141 attgacagct ggacaagttg cgaccctcta cgagtcctct atgggcttta ggcatggtcc
     7201 gaaatctttt attaatgacc gtaccttagt cattggattt gtcaataatg atgcttacgt
     7261 tagacagtac gatttggaca tgttagagga aatccaagca gatggcattg cccttaaaac
     7321 cttggctcta ttgcaaggag gggatatcaa cttttcagag gaccaattcc gactagacac
     7381 ccgtcactta ttgccagacg cttacttagc ttttcccatg attttagtcg cgcagacctt
     7441 ggccctctta acggccgtta cattaggaaa ttcccctgac accccatctg cgacaggaac
     7501 ggttaatcgt gtggtcaaag gagtaacgat tcacccttac ccgactagta gtcgtcaatg
     7561 caacaaggct taaagctttt gtgtagaagc cgtaaaacga aatgattttg tgctagtagg
     7621 ccaaaagaaa aaccctcctg atacaggaag gttttttgta ttgtcttgct tattttgctg
     7681 cgtttgcgtc tttgagaccg tattttttgt tgaagcggtc cacacgtcca tctgcttgag
     7741 tgaacttttg acgtcctgtg tagaatgggt gtgaatctga tgaaatttcc acacggataa
     7801 gtgggtaagt ttcaccttca aactcaacag tttctttaga agcttttgtt gagccgctaa
     7861 ggaactggta acctgtagtt gtatctagga aaacaactgg acgataatct ggatgaatgt
     7921 cttttctcat cttaaaaaat tcctttctgc catgacactt gatgcatcat agttattaac
     7981 tattctagtg taacaaaact tgaatgactt gacaaggctt ttctttcctt attttttaaa
     8041 aatcctaaat ctcttggcaa acagcgatga gttctcggaa aatagcttga ttttcttcta
     8101 aattagctga gttggctccg ctagcaaggg gatgcccccc tccaccgtga cgcttagcaa
     8161 tgccattaat aatcttttct ttactgcgca tacgcacacg gtagttgccg tcagttaact
     8221 caacaaaaat agcccaagct tgaacgttat caattttacc aggagcacag acaatggcag
     8281 agctttctgc tagggtcacg tcaaaatgtt ttaaggtttc ttggctgata aggacataag
     8341 cagccccact ctcatcaatt gttaaatgct caaagacgta gctttgcagc tttgctattt
     8401 tcaaaggaaa cgaatccatt tgccttgaaa tcgcagcaaa gtcgaactcg aaatgtctga
     8461 gttggctagc aatggaaagg gttttactag tggttgaggc ataaagaaat cgccctgtat
     8521 caccaacgat accggtgtat aagagcttag cagccttgtc agagagagta agattctgac
     8581 taaaggcaaa gtctgcaatg atttcacttg cgctagaagc gcttgtgtcc acataataga
     8641 agtcaccata cacatcatcg ttgggatggt gatcaatctt aattaagcac ttccccagtg
     8701 tgtagcgctc atcatcaatc cttggtcgat tcgctgtatc tgtaatgatg accaaagcct
     8761 ctttatagtc tttgtcagtc acctgatcca tttggctaat ccaagctaaa ctaggctcat
     8821 caaaaccagt catcaaaacc tttttgtctg ggaaattttg tgcaataatt tctttcaagc
     8881 cggcctgact accaagagca tcagggtcag gattttgatg gcgatggata ataatagttt
     8941 ggtgagcttt tattttatct aaaattgttt caaaagttgt tatcatgctt taatctttct
     9001 ttttcaaaaa gaggaaaata accgtttaac atagtcttca aaaaacggtt tgtgtcataa
     9061 ggaggtgtgc gttatgttaa gtggctaatg ctagaatttt ttaagattgt caaagacca
//
LOCUS       DAUNLR010000059         9091 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUNLR010000059 DAUNLR010000000
VERSION     DAUNLR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9091
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.059"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            364..846
                     /locus_tag="VLL59_001521"
     CDS             364..846
                     /locus_tag="VLL59_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HER6509636.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            935..1987
                     /gene="citC"
                     /locus_tag="VLL59_001522"
     CDS             935..1987
                     /gene="citC"
                     /locus_tag="VLL59_001522"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HER6509637.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGAYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKASSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAVVINANPFTLG
                     HQFLVEKAARENGWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWELLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(2097..3491)
                     /locus_tag="VLL59_001523"
     CDS             complement(2097..3491)
                     /locus_tag="VLL59_001523"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HER6509638.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFV
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPTTESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREVGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEDIKEKII
                     GDEAVITCRPADLIEPQMIYLRDEIAPYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(3506..4084)
                     /gene="citX"
                     /locus_tag="VLL59_001524"
     CDS             complement(3506..4084)
                     /gene="citX"
                     /locus_tag="VLL59_001524"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HER6509639.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            complement(4077..5609)
                     /gene="citF"
                     /locus_tag="VLL59_001525"
     CDS             complement(4077..5609)
                     /gene="citF"
                     /locus_tag="VLL59_001525"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HER6509640.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPR
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDPYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEKLVEKILDVQDFDHP
                     SAVSLGKHAEHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            complement(5612..6499)
                     /gene="citE"
                     /locus_tag="VLL59_001526"
     CDS             complement(5612..6499)
                     /gene="citE"
                     /locus_tag="VLL59_001526"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HER6509641.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            complement(6487..6795)
                     /gene="citD"
                     /locus_tag="VLL59_001527"
     CDS             complement(6487..6795)
                     /gene="citD"
                     /locus_tag="VLL59_001527"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HER6509642.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGVDQYDWKEIDSWNV
                     "
     gene            complement(6983..8104)
                     /locus_tag="VLL59_001528"
     CDS             complement(6983..8104)
                     /locus_tag="VLL59_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HER6509643.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVTNQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            complement(8149..8544)
                     /locus_tag="VLL59_001529"
     CDS             complement(8149..8544)
                     /locus_tag="VLL59_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HER6509644.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            complement(8601..8924)
                     /locus_tag="VLL59_001530"
     CDS             complement(8601..8924)
                     /locus_tag="VLL59_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509645.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSVIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
BASE COUNT         2678 a         1858 c         1819 g         2736 t
ORIGIN      
        1 cttagagtaa tataaagcta aaattgaagg aatattagag aatcatgaag acagcttctt
       61 taacatcaat tggttgaaaa caaggatcag ataacattat cgctagatag tctgaagaat
      121 caaaaacaaa gtttgttaca taaataaatt cttgtcaaaa cttgtatttt ctatttgaac
      181 tgatacgatt gacaaaggct aaactaaaat agcttgactt ttttagaatc tttgtatttt
      241 ttgtcggatc ccctcctatt ttttccttga attgatctat ttaacctttt agaacaaggt
      301 ttatcgcata ctatttttag acaatttgtt ataataaaaa gaaacgactt gaggagataa
      361 aagatgccaa agagaataag aaaagctcta ggagtagttg ggaaactgat gtcaattgtt
      421 cctgacacta ctgaaattat tggaaaaacg attgataaca gtcgaccaat tatcgaaaaa
      481 cgtatggaac aaaaacatga aaaagagatg caactacgca cgatagatga tgtgattaat
      541 cttcctgttg atcaggcaca agctcatttg gaacaacttg gctttgtagt agccactata
      601 cctgctaagc ctcataaaaa atggcttcat agtaatctca atgaagtggt tgctatgtct
      661 ccaaaatctg gtaaatataa gataggaagc ctgatcaaac tctactacat tactgttgat
      721 gttttggaaa aaagtcaaga cttattagac caagaaaact tgcggactgt ggaacgcaat
      781 caaaaaatcg ctgatacttt tgagtctgtc aaacacattc gatttccttt taaaaaatgg
      841 cgttgataaa aaacagagtt gcctttagat agatcagcct gttttggtac taagttatgt
      901 tatgattcaa taaaattaaa gataaggaga agaaatgcct tactacacta tttcaaaagt
      961 ctttccttca gataaaacga caatggctag tgtaaagaac ctgcttcatc aagaaggtat
     1021 tcgtttggat gctcatttag attatacttg tgccatcatg aatgcgcaaa atgatgtgat
     1081 tgctaccggt gcttactttg gaaatagctt gcgctgtctt tgcgtatcca gtgcctatca
     1141 aggtgaagga cttcttaata ggattgtgag tcatctcatt gatgaagaat atgcccttgg
     1201 caactatcat ctttttgttt atacgaaggc ctcttctgct gcttttttca aagatcttgg
     1261 ttttactgaa attgtccata tcgacaatca catcagtttc ttggaaaata aaaaaactgg
     1321 ttttcaagat tatctgatga cacttaataa gcctgagcaa acacctggta aagtcgctgc
     1381 tgtcgttatc aacgctaacc cctttacctt agggcatcaa tttttagtag agaaagctgc
     1441 aagagaaaat ggttgggttc atctgtttat ggtcagtgaa gaccgcagtc taattccttt
     1501 ttcggtgaga aagaggttga ttcaagaagg tctagctcat cttgataatg tcatatatca
     1561 tgaaacaggt ccttatttga ttagccaagc gactttccca gcctatttcc aaaaagaaga
     1621 caatgacgtg attaagagcc aagctttgct ggataccgct atttttctaa agattgctca
     1681 aaccttacag attacaaaaa gatacgttgg agaagagcca accagccgag taactgctat
     1741 ttacaatgaa attatggcag agcagttgca gcaagctggt atcctcctag atattttgcc
     1801 aaggaaagct atcaatcagc agcaagatcc tatcagtgcc tcaacggcta ggcaggcatt
     1861 gaaagataat gattgggaac ttctggcaaa actccttccc aaaacgtctt tagattattt
     1921 ttgttcgcta gaagcccaac ccattattaa aaagatacaa gccacttcat ctgtcaaaca
     1981 ttactaagat aaaaaaccta tctgattatc aaaatcaggt aggtttttgg tattgttctt
     2041 acagcaaatg cgtttcacca aggagattaa tggttaagag gattagtcat tccctgttag
     2101 tcttgaatgt ccagttgtac agtaacttct tggaccggaa catcatagaa aggatcttca
     2161 cggcgtccca agaaatctct ggcttgctgt gggaaactcg catagcttaa cacgtcttct
     2221 tctgaacgag cgtatggagc aatctcgtca cgtagataaa tcatttgagg ctcgattagg
     2281 tcggctggtc tgcaagtaat aactgcttcg tcaccaatga ttttctcttt gatatcttct
     2341 gctaatggcg ctggtgattg accgtatagc cctcgaacat agtctttgat ttcatttgga
     2401 actaccttgt agcgttcccc tgagatgata ttcatcaagg cctgtgtgcc aaccatttgt
     2461 gataatggcg ttacaagtgg tggatatcca agatcggccc ttactttagg tacttctgct
     2521 aagacttctt cgtatttatc agctaggcct tgctcggtta attggctcaa taggtttgat
     2581 agcatgccac ctggaacttg gtaaatcaat gtttttggct cagtatcttt gactttagga
     2641 tttaaaatcc ctacttctcg atagtggtca cgaatagtgt tgaaatattc tgcaactttg
     2701 gccacctctt gcatatccaa gcctgtgtca aagcctaaat ccgtcaaggc aatcgccatt
     2761 gattctgtgg taggctgact ggttccccct gaaaaagagg aaatcgccgt atcaataata
     2821 tcagctcctg cttctgctac ttttaagtaa gtcatttctg aaataccact ggtagcatgg
     2881 gtatgaacct caagagggat agttgtattc tccttgatac atttgaccaa ttggtaacct
     2941 atttcaggag ttaagacacc agccatgtct ttgatacaaa tggagtccgc tccgatagct
     3001 tggtaagctt tcgccaattc aacaaagtaa tcaatggtat gtaccggact tgtcgtgtaa
     3061 gaaatggcaa cttgagcatg ccctccaaat tttttagtcg ctgaaacagc tgtttgcaag
     3121 ttgcgagggt catttaaagc atcgaagata cggacaatat caatcccgtt ttcaatggat
     3181 ttttgaacga aggatctgac cacatcgtca gcataattgc gatatccaag aaggttttgt
     3241 ccgcgtaaga gcatctgaag tttagtcttt ttcactgctt tacggatggc tcttagccgt
     3301 tcccaagggt cttcatttaa aaagcgtagg caggaatcaa aggttgctcc tccccacatt
     3361 tcaagggcat gataaccagc attgtctagc gtttcgagaa taggaatcat ttccttggtt
     3421 gtcatacgtg tggcaatctg actttgttga ccatcacgta aaactgtttc cgttatacgg
     3481 attttcgtca taattgttct cctcattaac ctgtcttatc tgatgacgat gattggttgt
     3541 ctttattgaa aaatgaatgg agtaattttg aaatagcagt ctgcatctcc tcgacactgt
     3601 gcttacgtag gcgaccgcag actttggcct ctttagaaca gataaaacat tgcctagggg
     3661 agcctcctaa tacggttctg ctaattgaat gaggcagatc attttgcaag accaagacat
     3721 ctaaatccat gagacgacct attggcaact ctgtctctaa ggctatcatt tttaacttca
     3781 ggtcgcggct aggtagactt gtgatgaggt aatactcata acccgttgta ggcagtaatc
     3841 gcaactggta acaaatctta tcgtcagcta aggcagtttg aatggcctta atcactatat
     3901 caaaagcttc aagaagttta ggagaggttt taattggtcc agggatattc atggtgaccg
     3961 ataataagct accttctggg tactccttta ataaatgcag ctgacgcaga gctctttctt
     4021 cgcgggctct taacatatca ctaagttgga tagcttcgcc tgaaaaataa gtgtctttac
     4081 acattgtaaa ccacatccat gaggctacca tcacggtatt caataagagc aacaacctta
     4141 tcaccatatt gaatacgctc aggtgtgcca acgatggcgt aagccttctc ttttagctcc
     4201 tcaatactaa attgtggcac attgagggat ttgaaatggt ctactaagtc ttgacgattt
     4261 gggttaatgg caattcccac ttctgtgacg accacatcga cacttgttcc tggtgtaatg
     4321 accgtattaa cctcatctac aaaagttggg atgcgtccgc ggataagtgg tgaaataacc
     4381 aaactcatct tagccgcaaa ggcagtgtcg cagtgccctc cagaagcgcc acgaatcacg
     4441 ccgtcagatc ctgtcatcac attaacattg aagttagtat caacttcaag ggctgataaa
     4501 atacaagtgt ctaattgatt gataacagca cccttgctca aaggtgaggc atacatgttg
     4561 gcatcaattt cataatgttc agcatgctta ccaagagaaa cagctgatgg gtgatcaaag
     4621 tcttggacat caagaatttt ttcaaccagt ttttcttcga gcaactccac catagcattg
     4681 gtaataccac caagagcaaa gctagctttg atattttctt taatcatagc ttcacgcatg
     4741 aaacgggtta ctgccaaaga agcgccacct gttccagttt ggaaagagaa tccttcttta
     4801 aaataaggag agttggtgat tactttagcg gcgtattctg caattaagag ttctttagga
     4861 tttttcgtaa aacgagttgc ccctttggcg attccttgag gatctccgat agcatccact
     4921 gttaccacat agtcaacatc tgtttgagga atgctgattg gggtattagg ataaggaacc
     4981 aaattatctg tcaagataac cacctgatcc gcatatttgg catcaatcat ggcatagccc
     5041 aaagaaccac aggttgcttt cccttttgtc ccattaacat ttccgtaagg atctgaactt
     5101 ggggcgccca gaaaggcaac atcaatatgg atatccccac tagcaatggc acgagcgcga
     5161 ccaccatggg agcgaataac cacaggattt tccattagtc cttctgagat ggctgcccct
     5221 actttgtcac gaagaccaga tgaagtgatg ttagtgacca caccattttt gatgtgatca
     5281 atcaaaggct catgtacatt agcgatggaa cttggggcaa tagacaggtt tttaatgccc
     5341 attttggcaa tttcctccaa gaccatattc ataatgaaat ccccttcacg gaaatggtgg
     5401 tggaaagaaa tggtcatgcc atctgttaaa cctgtttttt caatcgcttc acgaacagat
     5461 cctagtaatt tagaatctcg aggcttaact ggtttaatac ggcgacttga ttcgtcatac
     5521 tgtttgatat ttgcgagttc tccttcaaag acaccgtatt ggtcggcgta tggttgagga
     5581 atatctctac cgagtttatt tgttaccatc tttaaatatc ctcctcagat aaaacacctg
     5641 ctgctgttgc tagggcaatc acacgttctg cacgttcaac gattggttta tcaaccattt
     5701 ttccatttaa ggaaataacg ccagagcctt tgctttcagc ttcacgaatt gcccagatga
     5761 cttgtttggc atggtcaatt tctttttttg ttggggtata aatctcattg accagaggaa
     5821 tttggcgagg gttgatgacc gatttaccat caaatcctaa ctgtttgatc atgcgaactt
     5881 cgttttggaa cccttcggta ttattgacat cagaataaac agtatcaatg gcagcaattc
     5941 cagcagcacg agcagcgtgt aaaatcatgc tacgagcaaa gaataattct tgaccatctg
     6001 ggtaacgacg cgttttcata ttcgtgacat agtcttctgc tccaagagca ataccaatca
     6061 agcgcttaga agctttggca atctcacgag catttaggac accttcggct gattcaatgg
     6121 ctgccatcat gcgtgtgcga ccaacttcaa tgccgttttc gcgttcgaca cgttcaataa
     6181 cagcctccac atcaacaata tcttgggcag tctctgtttt tggaagacga atcacgttga
     6241 cacctgccaa aacaacagct tcgatgtcta aagccccaca agaatcaaga ccattcacac
     6301 gaacaaccgt ttcaacgctt gaataatcaa aagttttaag cgcaaaatga acgagagctc
     6361 tagaggtgtc tttttctttg agtgaaacag aatcttccaa gtcaaacatg attgaatcag
     6421 cgccaaataa aggagcatct cgaagcatgg ctgcattggc acctggcaca aacatcattg
     6481 ttcttcttaa acgttccatg agtcaatctc cttccaatcg tattggtcaa caccagctgc
     6541 gcgatgaaca gctgcgatgg ttctcgcttg aatggtgcaa tctaaagcgc ctttatcaac
     6601 agcctctact ttagcagccg tcaccttcaa attcactagg gtttgatgaa tgagttgacg
     6661 aatgtgattg ccaaattgtt tttcaacact actgtctagg gttattgtaa tggtttgctc
     6721 gtcattaggg gatactgtaa tcattaggtc acttgattca agtgaaccag caacggcagt
     6781 ttgtttaata tccattgcgt ttacctcctt gattttctta aatgatattg ttatttacta
     6841 actgggaaaa gtttgatcag gatctctgcg acaagataga gaatgcctaa cacgataaag
     6901 acacctgcca taccaagcgc cattagctca aaggaactaa tcaaatggtc catattaatt
     6961 gtcataaggt ttcctttctt tcttagctaa agtaagctag caacaaacca cctgcgataa
     7021 cagaggcgat ttggccagag acattggcac ctacagcata catgaggata aagttttgcg
     7081 ggtcttcatc tgttgccatt ttttgaatga cacgacttga cattggaaaa gctgaaatac
     7141 ccgcagcgcc aatcattgga ttaatcttct cttttcggaa gagattgaga aatttggcaa
     7201 acatgacccc accgatagaa tccatgataa aagcaagtaa accaaagacg ataattaaga
     7261 gtgtctgtac atttaagaac aggtctgcct gcattttaat agagatggtc aatccaagca
     7321 agatactaat aatgtttacc aattcatttt gagcagtttg tgacaggcga tcgagcacac
     7381 cacactcacg taataagtta ccgaacatca aaaagccaac taaaggtaga gaaattgggg
     7441 cgatgaaccc tgctactaag gtaatgatga ttgggaataa gattttagtc atttgagata
     7501 cattctcagc tttgtaagtc atacggatac ggcgctcttt tttcgttgtc actaatttaa
     7561 tggcaaatgg ttggataata ggaaccaggg ccatataaga ataggctgca accgtaattg
     7621 gacccagtaa atccttggcc agttggttgg taacaaagat agaagtcggt ccatctgctg
     7681 ctccgataat gccgattgaa gctgcttctt taatgtcaaa tccagccagt acggcaacaa
     7741 caacaacaaa gaaaatccca aattgcgctg cagcaccaaa caagagcatg aatgggtttt
     7801 gaagtaaagg accaaagtca atcatggcgc caataccaat gaaaatcaac agtgggaaaa
     7861 gttctgttcc aatcccaaaa ttgaagaggg catcaaaaac cccttcttgc tcgactccgt
     7921 taaccacttg agttaaaacc cctgagccag ggaaattcac aaggattgtt ccaagcccca
     7981 ttggcacaag tagagttggt tcgtattctt ttttaattcc tagatacatt aagagggcac
     8041 caatgaccat cataacaatt tgaggaatgg tgatggaggt tattcctgcg attaaagtgt
     8101 ccacaaattc acttcctttt ctgtctattt attctagtta tagtactatt aaccaatggt
     8161 aatgagacca tcgccaggat tgaccacttg acctggaccg acgtggatag ctgtaatggt
     8221 tcctgctgat gaggccacaa tctcattttc catcttcatg gcttctaaaa tcaatagtgg
     8281 ctgattttca gttacttggt ctcccactgc tactaagact tttaagatgg ttccaggcat
     8341 tggtgatgga atggcatccg ctcccgctgc agctactggc tgtggtgctt gcgcttcctc
     8401 cacttgtggg cttgcttcag tagggacagg tactggagtg gatattggtt gagcgggggc
     8461 agctgcttgg gcaggagcac cgatttcttc catttctaca agatactctt taccgtcaat
     8521 ggtaatttta aattttcgta acatcatttt tctcctatat gttattgtgt catgagttcg
     8581 tctaaagtat cgttcaccga ctaccttttg caatagatgg atgtcacccg aaactgactt
     8641 tctgggtaaa cacctgcagc gatacttgaa gcaattaaag aaacagtgat tgcctcagga
     8701 ttgcgcttga gaatgcgttt aaccttgaat tgactattag gtctatcgcc agcagcaata
     8761 acactggtaa ttaaagtaac ctttttgtaa tcacttttgt ctgcaggaat ataagcggga
     8821 atcttttccc agttttcaga aggttctatt tctgtactaa ggggcgagga ttctttcaac
     8881 ttctcttttt tagagtgttt aaaccatttt tgtaaaaact gcatgagcta cctctttttc
     8941 acatttacct atttagggaa ctagtaagtt tattatatac taccaatctt ttttgagatg
     9001 gcttttttgt gttctttcta agagcgcttt caatgtttca taaagttttt aaacagttac
     9061 cttttatttt atttttaggt aactgtttaa a
//
LOCUS       DAUNLR010000060         9004 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUNLR010000060 DAUNLR010000000
VERSION     DAUNLR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9004
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.060"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            230..913
                     /gene="rpiA"
                     /locus_tag="VLL59_001531"
     CDS             230..913
                     /gene="rpiA"
                     /locus_tag="VLL59_001531"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HER6509646.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEVPKAS"
     gene            990..2201
                     /locus_tag="VLL59_001532"
     CDS             990..2201
                     /locus_tag="VLL59_001532"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HER6509647.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDIA
                     MIGESFLGHLK"
     gene            2217..2657
                     /gene="arsC"
                     /locus_tag="VLL59_001533"
     CDS             2217..2657
                     /gene="arsC"
                     /locus_tag="VLL59_001533"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HER6509648.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSSYIKEDGEIVNPIEVKGEKDVIDD"
     gene            2641..3450
                     /locus_tag="VLL59_001534"
     CDS             2641..3450
                     /locus_tag="VLL59_001534"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HER6509649.1"
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            4035..4748
                     /gene="deoD"
                     /locus_tag="VLL59_001535"
     CDS             4035..4748
                     /gene="deoD"
                     /locus_tag="VLL59_001535"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HER6509650.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGRRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            4741..5529
                     /locus_tag="VLL59_001536"
     CDS             4741..5529
                     /locus_tag="VLL59_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HER6509651.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRIIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRCEPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(5609..6514)
                     /locus_tag="VLL59_001537"
     CDS             complement(5609..6514)
                     /locus_tag="VLL59_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HER6509652.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLSDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHSKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            6736..7272
                     /locus_tag="VLL59_001538"
     CDS             6736..7272
                     /locus_tag="VLL59_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509653.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKIPTGEFE"
     gene            7549..8241
                     /gene="pyrF"
                     /locus_tag="VLL59_001539"
     CDS             7549..8241
                     /gene="pyrF"
                     /locus_tag="VLL59_001539"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HER6509654.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            8299..8928
                     /locus_tag="VLL59_001540"
     CDS             8299..8928
                     /locus_tag="VLL59_001540"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HER6509655.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
BASE COUNT         2727 a         1632 c         1915 g         2730 t
ORIGIN      
        1 aaggtcagta aaggtcaaac aaaaacactt gattttcaaa aagctaaata aacacgaaaa
       61 gtaagtgctt atatgatgac tttagaataa atcataagtt ttaaaaagat catcctattc
      121 tatagcactt aggctgtcaa tgagagaaaa acaaatgttt tcattaacaa gttggcgctt
      181 tcatggtata ataaagtgct aagacgcaat tctattataa gggggaatca tggaagcact
      241 caaaaaaatt gccggtgtta ccgctgcgca atatgtgact gatggcatga ccattgggct
      301 tggaactggg tcaacggctt actattttgt tgaggaaatt ggccgtcgcg taaagcaaga
      361 aggactgcaa gtggttggtg tgactacgtc aagtgtgact agcaagcaag cagaagtctt
      421 aggcattcct ttaaaatcga tagatgatat tgatagcatt gacctcaccg tagatggtgc
      481 tgatgaagtg gataaggatt tcaatggaat caagggtggc ggcgcagcct tactaatgga
      541 aaaaattgtt gcaacaccaa caaaagaata catctgggtt gttgatgctt ctaaaatggt
      601 agagcatctg ggtgccttta agttaccagt cgaagtcgtt caatatggtg ctgatcgctt
      661 gttccgtgtc tttgaaaaag ctggttacaa accgtctttt cgtatgaaag gtgatagtcg
      721 tttggtgaca gacatgcaaa actatattat tgatcttgat ttgggttgta ttaaagatcc
      781 tgttgctttt ggtcacctgt tagatggaac agttggtgtt gtggaacacg gtctctttaa
      841 tggtatggtt gataaggtga ttgttgctag taaagacggc gttactgttt tagaagtgcc
      901 taaagcaagc tagtcttagc atataacagt gttaatgtat tttataggta ttggggagtc
      961 aaccgtaacc tcccctagat tggagactta tgtcaaaatt taatcgtatt cacttggttg
     1021 ttttagactc tgtcggtatt ggtgcagcac cagatgctga caaattcttt aatgctggtg
     1081 tagctgatac agattctgac accctcggtc atatttcaga aacagcaggc ttatcggttc
     1141 caaatatggc aaaaattgga cttggaaaca tttctcgtcc aataccacta aaaactgttc
     1201 caacagaaga taatcctact ggttacgtga ccaaattgga agaagtatct cttggaaaag
     1261 ataccatgac aggccattgg gaaattatgg gcttgaacat tacagaacct tttgacactt
     1321 tctggaatgg tttcccagaa gagattttaa ctaagattga agaattctca ggtcgcaaaa
     1381 ttattcgtga agctaataaa ccctattcag gaactgcggt tattgatgat tttggtccgc
     1441 gtcaaatgga aacaggtgag ttgattgttt acacctcagc agacccagtg cttcaaattg
     1501 cagcccatga agacattatt cctgtggaag agctttacaa gatttgtgaa tatgctcgct
     1561 ccatcacgct tgaacgccct gcccttttag gccgtattat tgcgcgtcct tatgtaggcg
     1621 aaccaggaaa ctttacacgt acggctaacc gtcatgacta tgcagtgtct cctttccaag
     1681 ataccgtttt gaacaaactg gctgacgcag gtgtcccaac ttatgccgtt ggtaagatta
     1741 atgacatctt taatggttca ggtattacaa acgacatggg acacaataag tcgaacagcc
     1801 atggtattga cacgcttatt aagactcttc aattacctga gtttactaag ggattctcct
     1861 ttactaacct cgttgatttt gatgccaact ttggtcatcg tcgtgaccca gagggttatc
     1921 gcgactgctt gcatgaattt gacaatcgcc tacctgaaat catcgcaaat atgaaagaag
     1981 acgatttgct tctcatcact gctgaccatg gtaatgaccc aacctatgca ggcaccgacc
     2041 acactcgtga atacattcca ttgcttgcct actctgcatc ctttactgga aatggtctta
     2101 ttccacaagg gcattttgca gatatttcag cgactgttgc agaaaatttt ggagttgata
     2161 tagccatgat tggggagtca ttccttggtc acttaaaata agaaaattag ttgataatgg
     2221 aagaaatcac gatttatcat aatccaaact gtggcacttc acgtaatgtt cttgccatga
     2281 ttcgccatgc aggtattgag cctactatta ttgagtattt gcagacgcca cctaatcggg
     2341 agactttaat tgagctctta caatcgatgg gaatctctgc gcgagaactc ttgcgaacca
     2401 atgttcctga atttgaggct catggattag caaatcaagc agtagctgag aaagacgtta
     2461 ttaatgccat gttgacggat ccaattttga tcaatcgtcc tattgttgtg actcgcaaag
     2521 gagtaaaact ttgccgtcct tctgagacct tactggatat tcttcctgtt cccctgccta
     2581 gttcttatat taaagaggat ggcgagattg tgaaccctat tgaggtaaaa ggagaaaaag
     2641 atgtcattga tgactaaaat taacgaaaca aaagactttt tagttgctaa aggaattgaa
     2701 gctccagaat ttggattaat tctgggttca ggacttggtg aacttgctga agaagtagag
     2761 aatcctgttg ttattgatta tgcagatatt ccaaactggg gcaaatcaac agttgttggc
     2821 catgctggaa aattagtcta cggtgattta gctggtcgta aagtacttgc cctacaaggt
     2881 cgtttccatt tttacgaagg aaacccgctt gaagtggtga ctttccctgt tcgtgtcatg
     2941 aaagctctgg gatgtgaagg cgttcttgtc acaaatgcag ctggtggtat cggctacggc
     3001 ccaggtacct tgatggcaat cacagaccat atcaatatga ccggaaataa cccactaatc
     3061 ggtgaaaact tggacgagtt tggtccacgc ttccctgata tgtctgatgc ctatactaag
     3121 gtttatcgca ataaggcaca tgaagtggct gaaaaaatga acatcaaact agaagatggt
     3181 gtttatatgg gcttaactgg tccaacttat gagacaccag cagaaatccg tgctttcaaa
     3241 gtattaggag cagatgctgt cggcatgtca actgtgccag aagttattgt ggctgctcat
     3301 tctggactta aagtacttgg catttcagcc atcactaact ttgcagctgg tttccaatca
     3361 gaattgaacc acgaagaagt tgttgaagtg actgaacata ttaaagaaga tttcaaaggt
     3421 cttgttaaag ctattttagc tgagttgtag gacaaacaaa atcaactgga gcattattac
     3481 aggaatgtta ttttatgtcg tcagtttggc acatctgttc gcaataaaaa aatcaaaaaa
     3541 taatcacggg gtgtgagttc catgaatgtt gaactcagat tctagctttt ctaactaaca
     3601 taaccaacga agggaaagag acgtattcgg tttaaattaa gcatggactc gaatatttct
     3661 tcgtattaat ttttaaataa taaaggaaag agagttagtc ctttcttatt tgaactcgat
     3721 ttttagctct cttcttctat tcaatatcaa ttatgaaagg aatggggttg tattcaattg
     3781 aatacgggcg gaaagctcgg aaactagata aactaacttt tgtgctcaca catggcgtta
     3841 gttccctaaa tttcagttgc tttctgtccg ccctctgacc ttctacaaaa taaaaggaaa
     3901 ggtagggcta actgtattca ttgaattgaa tacgggcgga gaactgtgta aaaaagataa
     3961 actgtctagc atctgggatg cgtcgtcagt ttcctatttt tactttgttc tttgtcgcct
     4021 ttaatatctt aataatgtct atccatattt ctgccaaaaa aggtgatatt gctgataaaa
     4081 ttcttctacc tggagaccct ttgcgcgcga aatttatcgc tgaaaatttc ctagaagatg
     4141 cagtgtgttt taacgaagtg cgtaacatgt ttggctacac aggaacttac aaagggcgcc
     4201 gcgtttctgt catgggaact ggtatgggga tgccttcgat ctctatctat gctcgtgaat
     4261 taatcgttga ttacggtgtc aaaacattga tccgtgttgg tactgcgggt gcgattgacc
     4321 cagaagttca tgtgcgtgaa ttggtgcttg cccaagcagc agcaaccaac tcaaatatta
     4381 tccgtaatga cttcccagaa tttgatttcc cacaaattgc tgattttggt ttacttgaca
     4441 aggcttacca tatcgccaga gaaatgggag taacaactca cgttgggaat gtgctttctt
     4501 ctgatgtctt ttacactaac atgcctgagc gtaatatggc tcttggtaaa ttgggtgtta
     4561 aagccatcga aatggaagca gcagctcttt actatttagc tgctcagcac catgtcaaag
     4621 cccttggaat catgacgatc tcagataact tgaatgatcc aaccgaagat actacagctg
     4681 aagagcgcca aaccactttc actgatatga tgaaggtcgg cttggaaacc ttaattgcca
     4741 atgactaata atcaaacact agacatcctt ttggatgtct atgcttataa tcacgccttt
     4801 agaattgcta aagccttgcc aaatatccct aaaactgccc tctatttact agagatgtta
     4861 aaagagcgca gagaattgaa ccttgccttt ctggcggaac atgcagcaga gaatcggatc
     4921 attgaagacc agtaccactg ttcattatgg cttaaccaat cgcttgaaga tgagcagatt
     4981 gccaattaca ttttggattt agaagttaaa gtaaaaaacg gtgctattat tgatttcgtc
     5041 aggtcagtgt cgcctattct ttaccgactt tttctcagac taatcacgtc agaaattcca
     5101 aacttcaagg cttatatttt tgatacaaag aatgaccaat atgatacctg gcattttcag
     5161 gccatgttgg aatctgatca cgaggttttc aaggcttacc tgtctcaaaa gcagtctcgc
     5221 aatgtgacga ccaaaagctt agcagacatg ttgacgttga cctccttacc tcaggaaatc
     5281 aaggacttgg tttttttgtt acgacatttt gaaaaggctg tccgtaatcc tctggctcat
     5341 ttgattaagc cttttgatga agaggaactg catcgcacca ctcatttttc ttctcaggct
     5401 tttttggaaa acattatcac cttggcgact ttttctggtg taatctaccg atgtgagcct
     5461 ttttactttg atgacatgaa tgccattatt aaaaaggagt tgagcctttg gagacaatct
     5521 attgtctgat atttatcaaa aaacacgata acttgaccga tacaggtctt actaccgtgt
     5581 ttttttagta tgacgattga aaaagaaatt aatcaaaggt tacttcttcg agaaggtatt
     5641 cgataaaacg ttcccccatt ttggacaagt tggctttttc atgcttgata aaaacaatgt
     5701 caatttcgtc agggacatct agcgggatag ccacaatctg gtcaccattt agattgctat
     5761 ttagaatacc actggcaacg gtgtagccat ctaaaccaat cattaagtta aagagggtgg
     5821 cacggtcact gaccacaatt gatttgctgt ggggcatctg ggacatcatc tcttctgaaa
     5881 aataaaagga gttgtgaatc ccttggtcat agctcaggta aggaaaatcg ctcaagtcgt
     5941 ccatgcttaa taggctttta gttgctagag gatttgattt gctgacaaaa atatgaggct
     6001 gtgccttaaa taatggagag gcagtcaaat gattgtcatc aaataatttg gtcaagacat
     6061 ctcggttata gtcgttgata aagagaacac caatttcaga tcgaaagttt ttgacatcat
     6121 caatgatttc ccaagttctt gtctcgcgca aaaagagttc ataccgagtc atgtcggtcc
     6181 gcttgaggag tgagacaaat gcattgacta cgaaggcata atgttgagat gaaacgctaa
     6241 agagctctcg gccagtattg tggtttttat agcggtcttc taacagtgat gtttgctcta
     6301 taatttgtcg agcataagat aaaaattcca ccccatcttt tgtcaaggtg atccctttag
     6361 gatttcggtt gaaaatggta atgcccatct ccatttccaa atccttgacc gcattggata
     6421 gacttggttg tgtgataaat aattgcttag cagcttcatt catagagccg cactcaacaa
     6481 ttttgataat ataatgcagt tgttgaattc tcataagtac agtctagctc aaaaaaaata
     6541 aagacgcaag cacaaacgtc atcatgggtt tagaactttg aaaaagcgct ggagtctttt
     6601 ctaaatatgg cctaggataa atatgattca attttgagag ttgaatctat caatttcatt
     6661 gcccttttat ttttcttgtg ttatattaat agtattaaca aataggtatt tttctaatca
     6721 aagggtggtg gtcgtgtgaa tgttactgaa caaaatagtc atcaaatctt aatccaaaaa
     6781 ttattggtca gtatccacta tttgactctt tttcgagatg aactgaagct tgtagaacga
     6841 actccttcta tacttggagg ggaatttcca gctcatttag tacagtctga gttgggagat
     6901 attgttgcgg ccattgatac cttggatatg cagcaacgct tgattgagtc taccttttgg
     6961 tatgaagaat cagcttttaa gttgatgaac aaaactttgg atattgtcga taattggatt
     7021 aaaggagtgg atcatctgat agatttatgc cagtccaaag aagtctttca aattattatt
     7081 ggagataaac gcattcgagt ttttggggtc ttaagtgatg ttttttcatc tttaaaagtg
     7141 agtgctttgt cacttaagga agctcctatt ccggatgtgc tctatgaaca tatccagagg
     7201 gttaatcttg aagaagaagc ttttataaaa tattaccaaa gccctaagat acccacaggt
     7261 gagtttgaat aaatgattgg gtaaaaatga taaaatgagt tgacgtaagt atacaaaaaa
     7321 agatatagta ggaaaaatgt gttcaaataa caaaaagttt tgacatcttg ttttaaaaaa
     7381 gctataatag tttaaattta gacaccttta agtgagtcca gagaggcaaa caaggtatac
     7441 aagataaaaa aagggaattc ccttttagtt tgctgtagcc tcgcttcttt ggtagcgagg
     7501 ctttttggtg cttaatgaga tattgacaca ttatagaaag gataagttat gaaagaagaa
     7561 cgcccaatta ttgctttaga cttttcatca tttgaggaga ctaaagcatt tttagactta
     7621 tttccagcag aagaaaaact atacgtgaaa attggtatgg aattatatta tgcgcaagga
     7681 ccagatattg ttcggtatat caaatcgtta gggcataatg tatttttgga tttaaaatta
     7741 catgatattc caaatactgt tcgtgctgct atggcagttc ttaaagaatt agatattgat
     7801 atggcaactg ttcatgcagc tggtggtgta gagatgctaa aagcagctcg agaaggacta
     7861 ggtcaaggcc ctaccttaat tgcggtaacg cagctaactt caaccagtga agaccaaatg
     7921 cgtggtgatc aaaatattca aacgagtctt ttagagtctg ttttgcatta cagcaagggg
     7981 gcagctaaag ctcagctaga tggggtggtt tgttcggcac aagaagtaga agctatcaag
     8041 gcggtgacgc ctacgggatt tacttgctta actcctggca ttcgtcctaa aggcagtaat
     8101 attggcgatc aaaaacgagt gatgactcca aaccaagcaa gacgcattgg aagtgattat
     8161 attgtggtag ggcgaccaat tacccaggca aaagacccag tggctgctta ccaagccata
     8221 aaagctgagt gggcaggcta acagataaga ttaggaaacc aacacttgtc tgttaaagaa
     8281 gaaaaaggag aataagaaat gacactagca agccaaattg caactcaatt acttgatatt
     8341 aaagctgttt atttaaagcc tgaagaccct tttacgtggg catctggcat taaatcacct
     8401 atttacactg ataatcgtgt caccctttct tatcctaaga ctcgtgattt aattgagaat
     8461 gggtttgtgg aaactatcag ggctcatttc ccagaagttg aggtcatcgc tggtacagct
     8521 acagcaggta ttcctcacgg tgccattata gcagataaaa tgactcttcc ttttgcttat
     8581 attcgcagta agccaaaaga tcatggagca ggcaaccaga ttgaggggcg tgtgcttaaa
     8641 ggccaaaaaa tggttatcat tgaagatttg atttcaacag gtggttcggt actagatgca
     8701 gccgcagcag ccagtcgtga gggagctgac gttctgggag ttgttgcgat tttcacttat
     8761 gagttaccaa aagctagtca gaattttaaa gaagctggta tcaagttgat tacgctttct
     8821 aattatactg agctaattgc agttgcaaag ttgcaaggct atattactaa tgatggttta
     8881 catttactta aaaaatttaa agaagaccag gtaaactggc aacaataagg aactatcagc
     8941 caggtttatt tttaatgaaa aaatctcttt agccccaatt ccaaatgtta tgttttgatt
     9001 gttt
//
LOCUS       DAUNLR010000061         8842 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUNLR010000061 DAUNLR010000000
VERSION     DAUNLR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8842
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.061"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            90..956
                     /locus_tag="VLL59_001541"
     CDS             90..956
                     /locus_tag="VLL59_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HER6509656.1"
                     /translation="MKMKKKFFLLSLLVLSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            967..1902
                     /gene="pstC"
                     /locus_tag="VLL59_001542"
     CDS             967..1902
                     /gene="pstC"
                     /locus_tag="VLL59_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HER6509657.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPESLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1892..2779
                     /gene="pstA"
                     /locus_tag="VLL59_001543"
     CDS             1892..2779
                     /gene="pstA"
                     /locus_tag="VLL59_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HER6509658.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            2795..3598
                     /gene="pstB"
                     /locus_tag="VLL59_001544"
     CDS             2795..3598
                     /gene="pstB"
                     /locus_tag="VLL59_001544"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HER6509659.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            3611..4369
                     /gene="pstB"
                     /locus_tag="VLL59_001545"
     CDS             3611..4369
                     /gene="pstB"
                     /locus_tag="VLL59_001545"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HER6509660.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            4437..5090
                     /gene="phoU"
                     /locus_tag="VLL59_001546"
     CDS             4437..5090
                     /gene="phoU"
                     /locus_tag="VLL59_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HER6509661.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5295..7832
                     /locus_tag="VLL59_001547"
     CDS             5295..7832
                     /locus_tag="VLL59_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HER6509662.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIGNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNHHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQSNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQSTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            8178..>8842
                     /locus_tag="VLL59_001548"
     CDS             8178..>8842
                     /locus_tag="VLL59_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6509663.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILK"
BASE COUNT         2722 a         1484 c         1816 g         2820 t
ORIGIN      
        1 aaagcatagg tagatatgtt actataaaga atatgtggca cttagtttct acatatatac
       61 cctttatttt tacgaatagg aaataaataa tgaaaatgaa aaaaaaattc tttttgttaa
      121 gtcttttggt cctatcaact ttctttttat ccgcatgttc tagctggatt gataaaggtg
      181 agtcaataac cgctgtagga tcaacagcac tacaaccctt agtagaagca gtagctgatg
      241 aatttggaag cagtaatcta ggcaagactg tcaatgttca aggtggtggt tcaggtacag
      301 ggttgtctca agttcaatca ggagctgtcc aaattggaaa tagtgatgtc tttgcggaag
      361 aaaaagatgg tattgatgct tctaaattag ttgatcatca agtagctgtt gcaggacttg
      421 cagttattgc caatcctaaa gtcaaggttt ccaatctcag tagtcagcag ttgcaaaaga
      481 ttttttcagg agaatatacc aattggaaac aagttggagg agaagatctt gcgatttcag
      541 tgatcaaccg agcagcaagt tctggctcac gagcaacctt tgacagtgtt atcatgaaag
      601 gggtcaacgc taaacaaagt caagagcaag actccaatgg gatggttaaa tcgattgttt
      661 cacaaacacc aggtgccatt tcttaccttt cctttgccta cgttgattca tctgttaaat
      721 ctttgcaatt aaatgggttt aaggcaaatg ctaagaacgt ggctacaaat gattggccaa
      781 tctggtccta cgaacacatg tataccaaag ataaaccaac agggttgacc aaggaatttc
      841 ttgattatat gttttcagat gaagtacaac agaacattgt tacacatatg ggatatattt
      901 cgataaatga tatggaagtg gtcaaatctc atgatggaaa agtaacaaaa aggtaatgga
      961 ggaattatgg aaaatcagga attggctaaa aaattagcct caccatcaaa gaattcaaga
     1021 cttgaaacct ttggccgcac cattacgttt ttgtgtctgg ctttgattgt ttttatcgtt
     1081 gcgatgattc tgatcttcgt tgctcaaaaa gggttgtcaa ccttctttgt tgacaaggtt
     1141 aatctttttg atttcttgtt tggaaaggag tggcaaccaa gtgtgaaaaa tgcggccggc
     1201 attccttatc ttggtgctct gccaatgatt acaggatcct ttttggttac cattttatct
     1261 gctattattg ccaccccatt tgccattggc gcagccgttt ttatgactga aatctcacct
     1321 aaatatggcg ctaaattatt acagcctgcg gttgagcttt tggttggaat tccttcggtt
     1381 gtttatgggt ttatcggttt gcaagtgatt gttcctttta tgcgctctat ctttggtggc
     1441 acaggttttg gaatcctatc tggggtctgt gtcttgtttg ttatgatttt accaacagtg
     1501 acttttatga caacagacag tctgcgggcg gtgcctcgtc attaccgcga agcgtctatg
     1561 gctatgggag caacacgttg gcaaaccatt tggcgtgttg tccttaatgc agctcgtcca
     1621 ggaattttta ccgctgttat ttttggaatg gcgagagctt ttggagaagc cttggctatc
     1681 caaatggtag tcggtaactc tgcagttatg ccagagtctc tcacaactcc agcagctacc
     1741 ctaacttctg tcttgacaat gggtatcggt aataccgtta tgggaacggt ccaaaataat
     1801 gtgctttggt cccttgccct agtcttatta ttaatgagtc tggccttcaa ttcccttgtc
     1861 aaattaatca cgaaagaaag aaagagaaat tatgaacgct aaaaaagtcg ataaagtagc
     1921 aactggtact ctttatacca ttgctggaat tattgtagct attttagctt ccttaattct
     1981 atatatcctt gtccgtggct tgccacacat cagctggtcc tttttaacag gaaaatcgtc
     2041 ttcgtacgaa gctggtgggg gaattggtat ccagttgtat aattccttct tcctattgat
     2101 tgttacttta attatttcca ttcctttatc aactggagcg gggatttact tggctgaata
     2161 tgccaaaaaa gggcctgtta ccaactttat tagaacctgt attgagattc tgtcttccct
     2221 accatctgtg gttgtggggc tctttggtta cttgattttc gttgtgcagt ttgaatatgg
     2281 cttttctatt atttcagggg ctcttgcttt gacggtcttt aatcttcctc aaatgacccg
     2341 taatgttgaa gatagtttac tgcatgttca tcatacccaa agagaagcag gattagcttt
     2401 aggcctgtca cgctgggaaa cggtttttta tgtggttatc ccagaagctc tcccgggaat
     2461 ggtaacaggt attgtcttag cttcaggtcg tatttttggt gaagcggcag cgcttatcta
     2521 tactgctggt caatcagcac cagctctgga ttggtcaaat tggaatccac ttagtgttac
     2581 tagtccaatc tctattttcc gtcaatctga gacccttgct gttcatattt ggaaagtcaa
     2641 tagcgaaggg acaattccag atgctactct tgtatccgca ggaagtgcag cagtgctatt
     2701 aatttttatc cttattttca acttttcagc tcgctttatt gggaagaaac ttcattctaa
     2761 aatgacagca gcgaaataag atattggaga aatcatgaca gaatacaatt ggaatgaacg
     2821 tcatatcatc acttttcctg aagaaacgct tgctctagct accaaggatt tacatgttta
     2881 ctatggtgcg aaagaagcta tcaaagggat tgatatgcag tttgaaaaac ataaaataac
     2941 agccttgatt ggtccatctg gttgtggcaa atcaacttat cttcgtagtc ttaaccgcat
     3001 gaacgatacc attgatattg ctcgggttac aggtgagatt ctttatcagg gcattgatgt
     3061 taatcgaaaa gacatgaatg tttacgagat tcgcaagcac ttaggaatgg tttttcaaag
     3121 acccaatcct ttcgctaaat ccatttataa aaacattacc tttgcccatg aaagagctgg
     3181 tgtgaaagac aaaaaagttt tagatgaaat tgttgagact tcactgaaac aagccgcgct
     3241 ttgggatcaa gttaaagatg accttcacaa atcagccttc accttatcag ggggtcagca
     3301 acaacgcttg tgtattgcta gagccatttc tgtcaaacct gatattctat taatggatga
     3361 accagcctct gcccttgacc cgattgcaac gatgcagctg gaagaaacca tgtttgaatt
     3421 gaagaagaat tacacgatta ttattgtgac ccacaatatg caacaagcag ctcgtgccag
     3481 tgattacact gccttcttct atttaggcaa cctcattgaa tatgataaga cacgtaatat
     3541 tttccaaaat gcgcaatgtc agtcaacaaa cgactacgtt tcagggcact ttggttagaa
     3601 aggtaatatg atgacagaac ctattttaca gatcagagac ctttctgttt actacaatca
     3661 aaagaaaacg ttaaaagatg tctctttgga cctttatcca aatgaaataa cagctttaat
     3721 tggtccttct ggatctggga aatcaacgct cttgcgttct atcaaccgta tgaatgattt
     3781 gaatcctgaa gtaaccatta caggctctat cgtctataac ggacacaata tttatagtcc
     3841 aaggacagat acggttgatt tacgcaaaga aattggtatg gtattccaac aacccaaccc
     3901 atttccgatg tctatttatg agaacgtggt ttacggcctt cgcttaaaag gtatcagaga
     3961 taaatcaatc ttagaccatg ctgttgaaag ctctcttaaa ggggcttcca tttggaatga
     4021 agtcaaagat cgtttacatg attctgcggt tggcttatca ggcggacagc aacagagagt
     4081 ttgcatagct agagttcttg ctaccagccc cagaataatc cttttagatg aacctacctc
     4141 agctcttgat cctatctcag ctgggaaaat tgaagaaaca ttattgttat taaaaaaaga
     4201 ttatacactg gctattgtga cccgctcaat gcagcaagcc tcacgtttat cagatcgaac
     4261 aggttttttc ttggagggtg acttacttga gtgtggtcct acaaaagcca tgtttatgaa
     4321 tcctaagcgc aaagaaaccg aagactatat ttctggtaaa tttggttgag aaagacgtat
     4381 atggttgacc cctctgtgtt tttattataa tgactagatt gtaggaagaa aaaatcatgt
     4441 taagaacgaa atttgaagaa gaattagata aattgcataa ccagttttat tcaatgggaa
     4501 cggaagtatt ggcacaaatc aataaaactg ttcgtgcctt tgttagtcat gatcgtgaat
     4561 tggccaaaga agttatcgaa gaagatgaca ctattaataa ttttgagaca aagcttgaaa
     4621 agaaatcgct ggaaattatt gccctacaac agccagtttc gaatgatctt agaatggtta
     4681 ttactgtttt aaaggcatca agtgatattg aacgtatggg tgaccatgct gcttcgattg
     4741 ccaaggccac tattcgtatg aaaggtgagg agcgtattcc agtggttgaa gaacaaatca
     4801 accttatggg aaaagctgtg aaacagatgg tagaagaagc ccttaatgca tatatcaatg
     4861 ctgacgatac aaaagcttat gaaatcgcag cttctgatga gattatcgat caatatttcc
     4921 gtaatatcca aaccttagct gttgaagaaa tccgtaagtc tccagatgct gtttttgcag
     4981 gaaaagaata ttttcaagta ttaatgtatt tggaacgtat tggtgactat gctcgcaaca
     5041 tttgtgaatg gattgtttat cttaaaactg gaaaaattat tgaattataa gaaattatgc
     5101 tataatgaga ctgggaaaca gcttgccagt ccctggtttt atacgaaatt gtgcaagtta
     5161 gaaaatgaac taacaagaaa agttttcttt gctgaatctg attttgttag gttaacaaat
     5221 atatgtagac agagatgata cttaggtatc atctgttgat ctattatgat ttgttattag
     5281 aattaaggag ttatatgaag acagtagaac atctcatcga aacatttgtg cctgaaaatt
     5341 ataacatctt tttagatatt aatcgtcaga ctaaaacatt tacggggaat gttgcgatta
     5401 atggtgaagc tttagataat catgtggctt tccaccaaaa agatttggac attaagtcta
     5461 ttttgctcga taatgaagct gttatttatc aagtggataa cgacaatgaa gttgtgcgtg
     5521 ttgaattacc tgaaacagga atgatgacgc ttgtcattga attttcaggt agcattacag
     5581 ataatatgac aggtatttac ccttcatatt acactaaaaa tggtgagaaa aaagaagtca
     5641 tttcaactca gtttgaaagc cattttgcgc gtgaagcttt cccatgtatc gatgaaccac
     5701 aagcaaaagc tacttttgat ttaagcttga cctttgatca agaaattggt gagatagcgt
     5761 tatcgaatat gccagaagtc aatattgacc gtcgcgagga gactggtctt tggacatttg
     5821 atacgacacc aagaatgtca tcttacttgc tagcgtttgc gctaggagaa cttcatggaa
     5881 agactgtaga aagcaaaaaa ggaacaactg ttggtgtgta tgcgacaaca gcgcatcctc
     5941 ttagctcgct tgatttttca ttggatattg cagttcgtgt tatcaacttt tatgaagact
     6001 attttggagt acattaccca atcccgcaat ctcttaatat tgcgcttcca gatttttcat
     6061 ctggtgctat ggaaaattgg ggtttaatca cttatcgtga aatttattta ttagtagatg
     6121 aaaattcgac tgttcaaagc cgacaacaag ttgcacttgt aatcgcccac gagatagcac
     6181 accaatggtt tggaaacttg gttacaatga aatggtggga cgatctgtgg ttaaatgaga
     6241 gttttgccaa catgatggaa tatgtctcta tcgaggctat tgagccgtct tggaaaataa
     6301 tagaagattt ccaaacaggt ggtattcctc ttgctttaaa acgtgatgct actgatggtg
     6361 ttcaatcagt gcatgttgaa gtcaatcatc cagatgagat aaatacattg tttgatcctg
     6421 ctattgtcta tgcaaaaggt agtcgtttga tgcatatgtt acgccgtttt attggtgatc
     6481 gtgattttgc cattggctta catcactact ttgaaaaata tcaatatcga aatactgtcg
     6541 ggcgtgattt atggaatatt ttatcagata cttcaggcaa agacgtagct gcttttatgg
     6601 atgcttggct tgaacaacca ggttatccag ttttaacagc tcgccttgaa aacgatcaat
     6661 tgattttgag tcaaaaacaa ttttttattg gaaaaggtga agaaaaaggt cgcctttggc
     6721 cgattccttt aaacactaat tggcatggcc ttcctgaaac tttgacagag gcagaaatgg
     6781 tcattccaaa ctttagtcaa ttggcagcag aaaatgaagg agctctacgt ttcaatattg
     6841 gtaatacagc tcattacatt acagactacc aaggatcatt attagatgcc ttagtcactg
     6901 aacttgccca acttgataat acttctgctt tacaagttat tcaagaacgt cgtttattgg
     6961 cagatagtgg cttgatttct tatgctgaat tggttgactt aattgctcaa ttggacgatt
     7021 ctaagtctta tatggtagca gaagcggttc agcaagtggt ctctggtttg aaacgcttca
     7081 ttgatgaagg aagcttagca gaaaaatcct ttaatcgctt ggtaaccacc atctatcaag
     7141 aagactttaa tcaccatggt tttgagaaaa aagctgacga atcagatgaa gatgagatgg
     7201 tacgtcaggt tgccttggga cgcttgtggt tagcagaaaa tcagacgatt attgacggat
     7261 tgagaactat ttttgaagca tatcaaagca atattgcaag tattccagca gctgttcgtc
     7321 gcttggtttt agccaaccaa atgaaatatt ttgaaacaga tagcttggtt gatatttatt
     7381 ttgagactta tgtagcaact actgataata atttacgcag tgatttaacg gttgctttta
     7441 gtcaaacaaa acaatcaact actattagac gtattcttgt tagtttaaaa gataaagata
     7501 ttattaaacc tcaggattta tcttattggt acaatgcttt gcttggacaa agctttactc
     7561 aagatatcat ttgggaatgg gctagagaaa attgggattg gattaaatct gcacttggtg
     7621 gagatatgag ctttgataaa tttgttattt atccagcaag taattttaaa acaccaaaac
     7681 atctagcaga atataaatct ttctttgaac ctaagctaga tgatatggct attagccgta
     7741 atattaccat gggaattaat gaaattgaag cacgtgttgc tttgatcact aaagaaaaag
     7801 aagcagttat tgcagctctc agtcattact agaccataag caaaagagtt gggggacttt
     7861 ccagctcttt tttgtagtaa gctagcttcc tttcttagtt ccgtctataa ctaaatgatt
     7921 atccatagtt taattcaaaa ggagattgca ctttaaagcg aaggctatta gcctcttaaa
     7981 tactttttta ccaggtggtg aataagaaca attataaatg atttaatcat tatgctttaa
     8041 atgccttaaa ggagtattaa tattttagta aaccttaagc tttttgtagt atagtctcgt
     8101 tagaaattgt tatcagaaat gagactaagt taaatgaagt gatagttact ttatttaaga
     8161 acaattgagg tagagacatg ataaaaatat tattagtaga agatgacttg agcttatcaa
     8221 attccatttt tgatttttta gatgattttg cagacgtcat gcaagttttt gatggcgatg
     8281 aaggtttata cgaagcagaa agtggtattt atgatttgat tttgttagac cttatgttgc
     8341 cggagaaaaa tggctttcaa gtcttaaaag aattgcgaga aaaagatatt aaaattcctg
     8401 tgttgatcat gacagctaaa gagggtttag atgataaagg tcacggattt gaattaggtg
     8461 ctgatgatta tctgaccaag ccgttctatt tagaagagtt aaaaatgcga attcaagcac
     8521 tgttaaaaag aacagggaaa tttgcagata aaaatattag ttttggcaat ttagtggttg
     8581 acttagctcg aaaagaggtg aaggttgaag ggaaagtagt tgaattactt ggcaaagaat
     8641 ttgatttgtt ggtgtatctt ttgcaaaatc aaaacgttat tttaccaaag acacaaattt
     8701 ttgatcgttt atggggattc gatagtgata ctacgatttc ggttgttgaa gtttacattt
     8761 ctaaaataag aaaaaaatta aaaggtaccc gttttgttaa caggcttcaa actttaagaa
     8821 gcgtagggta tattttaaaa aa
//
LOCUS       DAUNLR010000062         8614 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUNLR010000062 DAUNLR010000000
VERSION     DAUNLR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8614
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.062"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            427..629
                     /locus_tag="VLL59_001549"
                     /pseudo
     CDS             427..629
                     /locus_tag="VLL59_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            831..1211
                     /locus_tag="VLL59_001550"
     CDS             831..1211
                     /locus_tag="VLL59_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HER6509664.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            1211..2059
                     /locus_tag="VLL59_001551"
     CDS             1211..2059
                     /locus_tag="VLL59_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HER6509665.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            2184..3392
                     /locus_tag="VLL59_001552"
     CDS             2184..3392
                     /locus_tag="VLL59_001552"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HER6509666.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDH
                     IEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            3389..5266
                     /locus_tag="VLL59_001553"
     CDS             3389..5266
                     /locus_tag="VLL59_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HER6509667.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGNYSDYLDEKAFEKETVEADLAKAIVTEEMPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(5364..5441)
                     /locus_tag="VLL59_001554"
                     /pseudo
     CDS             complement(5364..5441)
                     /locus_tag="VLL59_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            6156..6566
                     /locus_tag="VLL59_001555"
     CDS             6156..6566
                     /locus_tag="VLL59_001555"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HER6509668.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLNLTGLTAQICQHELDHLEGILI"
     gene            complement(6648..>8614)
                     /locus_tag="VLL59_001556"
     CDS             complement(6648..>8614)
                     /locus_tag="VLL59_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HER6509669.1"
                     /translation="SFTLLVTDVQADQVDVQFLGVNDFHGALDNTGTAYTPSGKIPNA
                     GTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSALLQDEPTVKVFNKMK
                     FEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEASHQTIVIANVIDKK
                     TNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEHYQFLDVAETIAK
                     YAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHSIDIIFAGHNHQ
                     YTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAPGIKTENSDIK
                     AIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLTIAKKTFPTV
                     DFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDVLNQQYDEN
                     QTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVNDFLYGGGD
                     GFSAFKKAKLVGAINTDTEAFITYITNLQASGKTVNATIKGVKNYVTSNLERSTKINS
                     AGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSFGKKETTTNKNTISNSTLPIT
                     GDNYKMSPIMTILALISLGGLNAFIKKRKS"
BASE COUNT         2751 a         1380 c         1779 g         2704 t
ORIGIN      
        1 ataatattta attttttaaa taatttttaa taaaattaaa caagcgattg caatggagac
       61 atcacaagag atacagtagt ggttgtgctt aaaaatgaac ggttttttga tgatatgttg
      121 ctgcatgagg aagtgagcaa taggagagct gtgatagaag aaagaaggga agaagcgttg
      181 atgaaattag acaaataaaa aaaagacctc atccagaaga ggtcgtggta taactgggga
      241 cgataggttc aattgataaa aaatcttgtt agcttacgat ctatgttgtt ttgaatgcct
      301 ttaactcaac atcgttaatg gattttgaga taaaaaaata aatccaatag tctggtactt
      361 tcctattttt tgtctgttaa aacgttttta ttttataatg gataaaagga gaagaagggc
      421 ggagcgatga ttaagctcta tgggtttaag tatgggttag ttggagaggt tttgcggcgg
      481 attgaacgcc taggatttac gtttgagcga ttagagctaa gacaagctag ttcgaaatac
      541 ttggctaagc atgatgaggc cttggtgata aaccttttta tcctggactt aaaacttacc
      601 tgaccagtgg ttctgtttta attgaggtgc agtacaagac cactaacggg tgtttttttg
      661 atataatgtc agtataagga cgactaaata taaataggtg aaaaaataga tatctgttca
      721 agagatagca ctgtttaaaa cgttatgcga aaatagtagt ttaggggcta ctttaataat
      781 cttcaaatct atgctataat ggatcatatt gataccaagg agaataaaaa atgcaattag
      841 ttcgtgaaaa agaatttgtc aaccagtacc attatgatgc tagaaattta gagtgggaaa
      901 aagaaaacgg aacaccagag accaattttg aagtgacttt tcagttgatt gataaagatg
      961 agcagcaaaa agaaacagta attgtatctg tattgcaatt tgttattgtc aaagaagaat
     1021 ttgttattag tggggtcatc tcacaaatgg ttcgtatttt agatcgttta gtggataaac
     1081 caagcgaatt tacgcaagag gaagttgaat ccttagctgc tcctttgcta gacatggtta
     1141 agcgattgac ttatgaagtc acagaaattg ccttggatcg tccaggtatt catttggagt
     1201 ttaaaaatta atgaaattag cagtaattac tgacagtaca gcaacactac caacagatct
     1261 gaaacaagat aaagctattt ttagccttga tataccagtt atcattgacg atgagaccta
     1321 ttttgaaggt cgaaatttga gtatagatga tttttatcaa aagatggctg actcccaaaa
     1381 tcttcccaag acaagtcagc caagtttatc tgaactagat aatcttttag gacttttgtc
     1441 ttctaagggc tatacacatg ttattggctt gttcttagct ggaggaatct caggcttttg
     1501 gcaaaatatt caatttttag ctgaagaaca tcctgagatt gaaatggcat ttccagacag
     1561 taagatcaca tctgctcctt taggtagtat ggtaaaaaat gtgctagatt ggtcacgtca
     1621 aggaatgaca tttcaagcta ttttaaacaa gctgcaagaa cagattgatg ggacgacagc
     1681 ctttattatg gttgatgacc ttaatcatct ggttaaaggc ggacgcctgt caaatgggtc
     1741 tgctcttctt ggaaatcttt tgagtattaa acctatctta cgctttgatg aagagggaaa
     1801 aatcgttgtt tatgaaaaag tgagaacaga aaagaaagcc atgaaacgct tggttgagat
     1861 tttaaatgac ttgatagcag acggtcagta taatgtgtct attattcact caaaagcaca
     1921 agacaaagct gattatttga aacgactctt acaagacagt ggttatcaat atgacattga
     1981 agaggttcat tttggagcgg tgattgctac tcatttagga gaaggagcca ttgcatttgg
     2041 cgtaacaccg aggctttaat tgtcgattag aaaaaatagt taattgcaag aatcactaaa
     2101 acaataacaa aatgtgatag aacccaagta gcctaatcac actttagatt gggctacttg
     2161 gatgataggt tagaaaacaa cgtatgaaat taatgacaat gccttctgag tttcagaagg
     2221 ctttacccat attgactaaa ataaaagaag ctggttatga agcctacttt gtgggaggaa
     2281 gcgtcagaga tgttttactc gagcgtccca ttcatgatgt agatattgca actagttcct
     2341 atcctgaaga gactaaagcg atttttaaca gaactgtcga tgttggcatt gaacatggta
     2401 cagtgctcgt gcttgaaaat ggcggtgagt atgaaatcac aacctttagg acagaagatg
     2461 tctatgttga ctatcgccgt cctagtcagg tttcttttgt gcgctcttta gaggaagact
     2521 taaaacgaag agactttacc gtcaatgcct tggccttgga tgaaaatggt caagttattg
     2581 ataaatttag aggactcatt gatttggagc aaaaacggtt acgagcagtg ggtaaagcag
     2641 aggaacgttt tgaagaagat gcactacgca ttatgagagg ctttcgattt gcggcgagtc
     2701 tggattttga cattgaagct gcaacttttg aagctatgag gagccattca cctctattgg
     2761 aaaagatttc tgtggaacgt tcttttactg aatttgataa attattgatg gcaccgcact
     2821 ggcgaaaagg gatttctgcc atgattgctt gtcaggctta tgactattta ccaggcttga
     2881 agcagcagga agcaggcttg aatcatctga tagtttcttt gaaagataac tttaccttta
     2941 gtgatcacca ccaagcttgg gcttatgtga tgattagttt agccattgag gatcctaaaa
     3001 gcttcctaaa agcatggaag acttcaaatg attttcagcg ttatgtcaca aagttgattg
     3061 ctctttatag aattcgtcag gaaagatctt ttgaaaaatt ggatatttac cagtacggca
     3121 aggaaatggc aagtctagtg gaaggcctcc gaaaagctca aagcttatct gttgacatgg
     3181 accacattga agctttagat caagcgctag ccattcataa caaatacgat atcgtcctta
     3241 atggttctca cctgattaag gattttggga tgaaaccagg tcctcagcta gggcttatgc
     3301 ttgagaaagt tgaattagcg attgtagagg gacgcctaga taatgatttc actacaattg
     3361 aagcatttgt tagagaggaa ttagcaacat gagccatttt ttggtggaga aattgacaaa
     3421 aacggtggga gataaaacag tctttcagga tatttccttt attattcatg actttgaccg
     3481 tattgggatt attggggtta atggaacagg aaaaacaact cttttagatg tcttgtcggg
     3541 aaggcttggt tttgacggag accattcacc attttctaaa gccaatgatt acaaaatcgc
     3601 ttacttaaca caagatcctg aatttaacga tgcatcctct gttttagata cggtattgtc
     3661 atctgatgtt aaggcgattc agctgattcg tcagtatgaa ctattgatgg cgaattatac
     3721 tgaagataaa caagagacct tagagtccct catgtctgaa atggatcgct tagatgcttg
     3781 gtctattgaa agtgatgtca aaacagtcct atcaaaatta ggcatcacgg atttggaaca
     3841 aaaagtggga gacctatcag gtggtatgag aagacgtgtc cagttagctc aagtattgct
     3901 aggagctgct gacttactct tgttggatga gccgaccaac catctcgata ttgacaccat
     3961 cgcttggtta acaacctatc tcaagacagc taaaaaaacc gtccttttta ttacccatga
     4021 ccgttatttc cttgatcatg tggctacccg tatttttgaa ttggataaag cgggactgac
     4081 agaatatcaa ggcaattacc aagactatgt gcgcttaaaa gcagaacaag acgaacgaga
     4141 tgctactaat ttacacaaga agaagcaact ctataaacaa gaattagctt ggatgaggac
     4201 gcagccacag gcgcgtgcaa ccaaacagca ggctagaatc aatcgtttca ctgacttgaa
     4261 aaaagaagtt caccaagaca gttctgcaga taaattggag atggctttcg aaacgagccg
     4321 aattgggaag aaggtgattc actttgaaga cctttctttt gcttatggcg accgacagtt
     4381 gattaaggat tttaacttga ttattcaaaa taaagatcgt attggaattg ttggagataa
     4441 cggcgtcgga aaatctaccc tgttaaatat catcaacggt gatctcaaac caacttctgg
     4501 gaagcttgat attggagata ctattcgtgt aggttatttc tctcagcagc tcaaagatat
     4561 ggatgagacc aaacgggtca ttaattacct tcaagaagtg gctgatgagg ttaaaacaag
     4621 cgtgggaaca acgagtatca gtgagctttt agagcaattt ctttttccga gatcaagtca
     4681 tggcacgctg attgctaaat tatctggtgg ggagaaaaaa cggctctact tgctaaaact
     4741 gctcattgaa aagccaaatg ttcttctcct tgatgagcca acaaatgatt tagacattgc
     4801 caccttgacg gtcttagaaa actttttagc taactttgca ggaccagtca ttacggttag
     4861 tcacgatcgt tatttcctag acaaagtagc cactaagatt ttagcctttg aagaaggcga
     4921 tattcgtatt ttttatggga attacagtga ttaccttgat gaaaaagctt ttgaaaaaga
     4981 aacagttgag gctgacttag ctaaagcaat agtcactgaa gaaatgccac ttcctccgaa
     5041 agaggagaaa aagcgcatgt cctaccttga aaaacaagaa tgggctcaga tagaagataa
     5101 aatagcaact attgaggcta atattgaaga aattgaaaac caaatgttaa ctgtagttag
     5161 tgattatggc cagttagctc aattacaaaa ggaactcgat cagcgcaata atgatttatt
     5221 attggcgtat gaacggtttg agtatttgag tggactagac atataagtat actatggtaa
     5281 tgttatgttt ataataaaca agtgataata gaaaagaagt gctcttgcac tgagccccaa
     5341 aagttggcta ctctatttga agtaaaggat ttagttctgt attgtagagg actaagttct
     5401 tttcgtttta ttttgatacg tttattgttg caataatcga tgataatagt aggtagaacg
     5461 agtcaattta gccgttctta aaagaaaatc taatcagaac tcgtctttgt ccattcttta
     5521 taatggtttt ttgtcttctt ctttgcagag atgcttcttt caaacggagt tccctcagtt
     5581 tttaagtgct aaatgtctag cttatcttca tagcttaatg tcatacaaaa acaccccaaa
     5641 cgttagattt tttatctaac gtttggggtg tagtttacat tatggcgctt cttttctatt
     5701 attacgtgag gaaaaatcaa gtaaaaaagt taagtcaact gaaaaacttg acagaaatat
     5761 tcagaaaatt tataatacta actattaaca acatatcagc tattaaagca tttcaaacag
     5821 caggtgtttt gtttggacct atcaaggctg taaatgcaag agaaagcagt atctggtttg
     5881 aaaatctcac aaagcaataa ctatctctct tagacatttg aagaagcaga cagtaaattc
     5941 gataatattg tgatgagaac ttagcaacaa tctgctgatg caggtcaatt tttatttggt
     6001 actcatattg cagaatttca taaagttgcc caagatatct tgaaataagg aatcacctga
     6061 tgttttaaac agatgatact aagtctatca tatggtgata atagtccatt gaacatgtag
     6121 tttatgaatt aaaaagaagg tttaaggaga taagaatgat tagagaaatc ataacagatc
     6181 attttttatt acagcaaaaa gcgcaagtcg ccaagaaaga agatctatgg attggccaag
     6241 atttacaaga taccttagcc ttttatagac aggaatgtct tgggatggct gccaatatga
     6301 ttggtgaaca aaagcgcatt gttattgtga gtatgggatt tattgatttg gtgatgttta
     6361 atcctgtgat ggtttctaaa aagggaattt accaaactaa agaatcttgt ttgtcattat
     6421 ctggctatcg caaaacacag cggtatgata agattactgt tgagtatttg gaccataatt
     6481 ggcgaccaaa gcgtttaaac ttaacaggcc taactgctca aatatgccag cacgaattag
     6541 atcatctaga aggtatttta atttaacaaa aaacctagag taggacactt taggtttttt
     6601 tggcgaaaat gcctgattat ataaggatga tcaattacta gtaaacgcta ggattttctt
     6661 tttttaatga aagcgtttag cccacctaag cttatcaagg caaggattgt cataatagga
     6721 gacattttat aattgtcccc tgttattgga agagtggaat tagagatagt atttttgttt
     6781 gttgttgtct cttttttgcc aaagctgtta ttagtgtttt cagtagaagt caaaaggtct
     6841 gaaatgactt cactagacac tatattgcca tcacgatttc taaaaacctt actaatgata
     6901 ctgtgtttgc cagcactatt aatttttgtt gatctttcaa ggtttgaagt tacataattt
     6961 ttaacccctt tgatagtagc attaacagtt ttacctgatg cttgtaaatt tgtgatatat
     7021 gtgatgaaag cttcagtatc tgtgttaata gctccgacta atttagcttt tttaaatgct
     7081 gaaaagccat caccgccacc ataaagaaag tcgttgacaa caacggtgta agtagttgtt
     7141 aagttaattt cttcaccatt gtctttataa accttaacta tcttgaaggg ggtatcagag
     7201 ttcttaggat cattatctgt ataagtgtat gttaaacctg acatttgaag aaaataggtc
     7261 tggttttcat cgtattgctg atttaggaca tcgtaaatgt gttgaccagt catttgaatg
     7321 acttgaagga tattaccaaa tggttgtaca gcctgtgcag ctccccaggt gatggtccgg
     7381 tcatttttga caactaggtc acttcgaata ccaccattat tggtcatagc aaagtcaaca
     7441 gttggaaaag ttttcttagc aatagtaagc tgagccgttg ttactaagtt accgacaggg
     7501 gattctttat caatattttc tgttttagaa atagttgaag aattagttgc agttccgatt
     7561 tttcgttcag taactgtttt aacaatatca ttagcatgat ttattatagc tttgatatct
     7621 gaattttctg ttttgatacc tggtgctaca gcaacaacat ttgctgatgg agttttaata
     7681 aaatcattgg tatcagtatc tagcgtacca cggacatctg cataagcttt tccttgagag
     7741 agggcttgaa cgatacgtgt tttaccgata gttccattag tgtattgatg attatgtcct
     7801 gcaaaaataa tatcaatgct atgttcggga tagatttggt tcactttttc cataaccgta
     7861 gccatttcat gatcaacaac accatcttta cttgttgcag gaatatgagc taaaaccaca
     7921 atagcatgaa catgttgttc ttgcagttct ttagcatatt tggcaatggt ttcagctaca
     7981 tctaaaaatt gatagtgttc atagttttgc tttaaaacga gatttggaat ctctgtagtc
     8041 acaacaccaa tgaagccaat cttaacgatt ttgtcattaa tggctatgtc ttttatagca
     8101 taaggtttcc aaccataggg gatatcatta gtttttttat caatgacatt agcaatgacg
     8161 atggtttgat gcgaagcttc gtgctcatat tgtttggtga tatcattaat tgttgattca
     8221 ggatcaggcg cttgacctgt catgatacgg ttaaattcat ctagtccttc gtcaaattca
     8281 tgattaccaa gagtgccata ttcaaatttc attttgttaa agacttttac agtaggctca
     8341 tcttgtaaaa gtgcagagtt agcaggactg gctccgacca tatctccagc ttgaacacgt
     8401 atacttgttc cgtcttgatt tgcttgcttg aagtctatct cagcgtcatc catataagca
     8461 cctaattgag cagccgtccc agcatttggt attttaccac ttggtgtgta agctgttccg
     8521 gtattatcaa gagcgccgtg aaaatcattg acgccaagga attgcacatc aacttgatct
     8581 gcttgaacat ctgtaactaa tagagtaaaa ctag
//
LOCUS       DAUNLR010000063         8215 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUNLR010000063 DAUNLR010000000
VERSION     DAUNLR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8215
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.063"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..1152
                     /locus_tag="VLL59_001557"
     CDS             <1..1152
                     /locus_tag="VLL59_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HER6509670.1"
                     /translation="GSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQL
                     GAETNAFTTFNQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMY
                     QDDADYRAYSGILQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFI
                     VGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFR
                     GYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHHFQFV
                     LISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQ
                     FSLYLSDSDKETYFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            1202..2227
                     /locus_tag="VLL59_001558"
     CDS             1202..2227
                     /locus_tag="VLL59_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HER6509671.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIAILGTVAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2241..2783
                     /gene="pgsA"
                     /locus_tag="VLL59_001559"
     CDS             2241..2783
                     /gene="pgsA"
                     /locus_tag="VLL59_001559"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HER6509672.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2785..3624
                     /locus_tag="VLL59_001560"
     CDS             2785..3624
                     /locus_tag="VLL59_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HER6509673.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3600..4442
                     /locus_tag="VLL59_001561"
     CDS             3600..4442
                     /locus_tag="VLL59_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HER6509674.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELKEV
                     LKHG"
     gene            4435..5235
                     /locus_tag="VLL59_001562"
     CDS             4435..5235
                     /locus_tag="VLL59_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HER6509675.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
     gene            5607..6221
                     /locus_tag="VLL59_001563"
     CDS             5607..6221
                     /locus_tag="VLL59_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HER6509676.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKDKSKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
     gene            complement(6635..7507)
                     /gene="sdaAA"
                     /locus_tag="VLL59_001564"
     CDS             complement(6635..7507)
                     /gene="sdaAA"
                     /locus_tag="VLL59_001564"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HER6509677.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKEQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIDSQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(7519..8190)
                     /gene="sdaAB"
                     /locus_tag="VLL59_001565"
     CDS             complement(7519..8190)
                     /gene="sdaAB"
                     /locus_tag="VLL59_001565"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HER6509678.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
BASE COUNT         2643 a         1384 c         1521 g         2667 t
ORIGIN      
        1 ggttctcttg acaataagtt gacagtcgat gacgaatcac gagatgctcc agcaggtatt
       61 gcacactttt tagaacataa actctttgaa gatgaatcag gtggagatat ttcattaaag
      121 tttacacagc taggagcaga gacaaatgcc tttacaactt tcaaccaaac gagtttcttc
      181 ttttcaacag ctagtaaatt tcaggaaaat ttggaactcc ttcaatattt tgttctttct
      241 gctaatataa cagatgaatc tgttagtaga gaaaaaaaaa taatcgggca agaaattgat
      301 atgtatcaag atgatgctga ctaccgtgca tatagtggaa tccttcagaa cttatttcca
      361 aaaacaagtt tagctaatga tattgctggc tcaaaagcat ccattcaaaa gatcacgaaa
      421 atattattgg aaacgcatca tacttatttt taccaaccta ctaatatgag tctattcatt
      481 gtcggtgata ttgatattga cgaaactttt ttagctattc aaaggtttca aaccacatta
      541 tcctatccag atagaaaaag ggtaactgtt gatcctttac actactatcc tgtcattaaa
      601 tcatcttctg ttgacatgga tgttactact gccaagctgg ttgttggttt tcgagggtat
      661 ctgaccttaa ctcagcattc actattaacg tatcgtattg ccttgaagct atttttatca
      721 atgcttatag gttggacttc taaaatctat catacgctat atgaagatgg taaaatagac
      781 gattcatttg atgtggatgt tgaaattcat catcattttc aatttgtatt aatatcactt
      841 gatacaccag agcctatcgc aatgtctaac tatatccgtc aaaaattagc cactataaag
      901 atatcaaaag agtttacaaa tgagcactta aatctattaa aaaaagaaat gtatggtgac
      961 tttattcaga gtttagactc tatagaacat ttaacccatc agttcagtct atacctgtct
     1021 gattctgata aagaaacata ttttgatatt ccaaaaatta tagaaagact cactctaaaa
     1081 gatgttgtta caattggaaa agcatttttt gaaaaagctg atgcttcaga cttcacagtc
     1141 ttcccaaaat agatgaaaat ctgttataat agggttacta tattattttt gaggtacctg
     1201 tatgagtgaa aaaagtcttg gtgaagtgtt aagagaatcg cgtgttggaa aaaatatcac
     1261 actagatgat atagaattga agacagggat ttcttcccat tacttgctgg caatggaatt
     1321 ggatcagttt aaaattattc cggaagaaaa atttgatcaa tttttaaaag aatatgctga
     1381 cattgttgag ttagatttca atactttaaa aagacgatac cgttatcaag ttaattccaa
     1441 aaaagacagt gatataaaat ctgtaactga gattgttgaa gagaagttaa gtaagaaacg
     1501 attacaagag aagttgttat cacatcagag catggggtat ggtcaaccgt tagaagtttc
     1561 taaaaacaaa gaaaccttag ttatccctgt aaagactgtt ggtttagata gcaaatcgcc
     1621 actaaaaacg atatcgcctg ttagccaatt taaatcagat aacaggttaa ttcctaaaaa
     1681 aaatgtgtca cgtatgaggc gaaatagcac tgacagtcgt tctaaaacgt cactatttcc
     1741 catagctata ttaggaacgg ttgcttttgc aattatcagt gttatcattt taggtgtttg
     1801 gcaacaattc gaaaagagtc aaagagctaa agaagctgaa gttgctttgc ttaaagcctc
     1861 tgagcagtct actaacggtt taaaaaataa ttcaaatgat cgcaaaactc aagtcacaac
     1921 tgaggggtcg ggtaattatt taatagcgac tgttactaaa tctaaagaga ccgttgatat
     1981 cagtgtgtct ttaactgagg cacaaagtag ttggatttct ctaacaaatt cagaaattgg
     2041 tgaaggtggt ataacattga ctcaagactc gccaacttat acagcgactt tacctgcaga
     2101 aataacagaa tcattgttga cacttggtgt gacaaaaggt gtatctgtaa caattgatgg
     2161 acaacctgtt gatctatcac ctttaacaag tactgactta agttatatca cgtttaagat
     2221 ccaataatta aggtagacta atgataaaaa aagaaaatat tcctaatcta ttaactcttg
     2281 ttcgaatcgc aatgattcct ttctttcttt ttattacttc ctcatctaat aaggtggggt
     2341 ggcatatttt tgcagctgtg atttttgcaa ttgccagttt taccgattat ctagatgggt
     2401 atcttgcgcg taagtggcat gtagccagta attttggaaa gtttgccgat cctctagcag
     2461 ataagatgct tgtcatgagt gcctttatca tgttagttgg acttggctta gttcctgcgt
     2521 gggtgtcagc tgttattatt tgccgagaat tggcagtaac tggtcttcga ttactacttg
     2581 ttgaaaccgg aggaaaggtc cttgcagctg ctatgccggg aaaaatcaaa acagcgacac
     2641 aaatgttgtc tattatttta ttactttgcc attggatatt cctaggaaac gtcttactct
     2701 atattgctct ttttttcact atttattctg gatatgatta ttttaaagga gcaagctttc
     2761 tttttaagga tacgtttaaa taacatgtca gctattattg aacttaaaaa agttacattt
     2821 aattaccata aagaccaaga aaaaccaaca ttagatggcg tatcgtttca tgtgaaacaa
     2881 ggtgagtggc tgtctatcat tggccataac ggatctggta aatcaacgac tattcgatta
     2941 attgatggat tattggaacc agaatcaggg tctattattg ttgatggaga tctactaacc
     3001 ataactaatg tttgggaaat tcgtcataaa attggtatgg tctttcaaaa ccctgataat
     3061 cagtttgttg gagcaactgt tgaagatgat gttgcttttg ggcttgaaaa taaaggtatt
     3121 gcacatgaag atataaaaga gagggttaat catgctttag agttagtcgg catgcagaac
     3181 tttaaagaaa aagaaccagc ccgtttatct ggtggccaaa aacagcgcgt agctattgca
     3241 ggtgcagttg ctatgaagcc taaaattatt attttagatg aagctactag tatgcttgac
     3301 cctaaaggac gattagagtt aatcaaaact ataaaaaaca tccgtgacga ctaccagctg
     3361 actgttattt ccattactca tgacttagat gaagttgctc ttagtgatag agttttagtg
     3421 atgaaagatg gtcaagtgga atcaacatca acaccagaac aattatttgc aagaggggat
     3481 gaactactcc aattaggtct tgatatccct tttacaacat ctgttgtaca gatgcttcaa
     3541 gaagaaggtt atcctgttga ctatggatat ctcacagaaa aggaattaga aaatcagtta
     3601 tgtcaattaa tctccaaaat gtaagttata cttatcaagc agggactcct tttgaagggc
     3661 gtgccctttt taacattaat ttagatattt tagatggttc ttatacggct tttatcggac
     3721 atactggatc cgggaaatcg accattatgc aattgctaaa tggtttacac gttccgacaa
     3781 cgggaattgt cagcgtagat aaacaagata taacgaatca ctctaaaaat aaagagatta
     3841 aatctattcg aaaacatgta ggattagttt ttcaatttcc agaaagtcaa ctatttgaag
     3901 agacagtttt gaaagatgtt gcttttggcc ctcaaaattt tggggtctct ccggaggaag
     3961 cagaagcttt agcgcgtgaa aaactagctc ttgttgggat ttcagaaaat ctttttgaaa
     4021 agaatccatt tgaactctca gggggtcaaa tgcgtcgtgt tgctattgcg ggtatccttg
     4081 ctatgcagcc aaaggtttta gttttagatg aaccgactgc tggtcttgat cctaaagggc
     4141 gtaaagaatt aatgactatt tttaaaaagt tacaccaatc tggcatgact attgttttag
     4201 taacccatct gatggatgat gtggccaatt acgcagattt tgtatatgtt cttgacaaag
     4261 gtaaaattat tttatcagga aaacccaaaa caatttttca acaagtcagt ttgcttgaga
     4321 aaaaacagtt aggagttcct aaggtgacta aacttgctca aaggcttgtt gatagaggaa
     4381 tacctatctc ttctttgcct attaccttag aggagctaaa agaggtacta aaacatggat
     4441 aagctgattc ttggtcgtta tattcccgga gattctctca ttcatcgtct tgacccaaga
     4501 agtaaattat tagcgatgat tatttatatt gtcattatct tttgggctaa caatgttgtg
     4561 acaaatttgt tgatgttgac ttttacttta gcagttgttt ttttgtcaaa aatcaagttg
     4621 tctttctttt taaatggggt taaaccaatg attggtatta tcctcttcac gactttattt
     4681 cagatgtttt tctcacaagg aggaaaagta atttttagtt ggtggttcat tagcataact
     4741 gatttaggat tgagccaagc tattttaatt tttatgcgtt tcgttctaat tattttcttt
     4801 tcaacgctgt taacgttgac gacaacacct ttaagcctat ctgatgcagt tgaatcatta
     4861 ttaaaacctt taacaagatt taaagttcca gctcacgaga tcggactaat gctttcttta
     4921 agtttacgtt ttgtgcctac tttaatggat gataccacgc gtattatgaa tgcacaaagg
     4981 gcccgtggag ttgattttgg agagggaaat ttaattcaaa aagttaaatc tattattcct
     5041 attttaatcc ctcttttcgc ttcaagcttt aaaagagccg acgcattagc tattgctatg
     5101 gaagctagag gttatcaggg aggagaaggg cgaactaaat atcgtcaatt agactggcag
     5161 ctaaaagata gtttagctat tggaatagtt tctttattgg gtttgctact ttttttcttg
     5221 aaaacctctt tgtaatattt tttagcacaa aacttttctt tattagtaag aagtgaattg
     5281 tacctcaaaa gttagataca acatctaatg attgaggtac ttttcttcat ttgaggaatt
     5341 gaaaaccgct atctcaacta tattaatcct cccaataata acaaatcgaa cgaaatctaa
     5401 aaggactgag tcctgttcaa tacagaacta aattattagt ttaatgatat tatcccgctt
     5461 tttaatgttg ctaagaagaa gagttttatg attttttaca acttcttata atatcaatgt
     5521 agttgtaata tttttaatat atcttcaata acgaggtaat aattaaaaga tattatggat
     5581 aacggagaaa agtgaggtat tattgaatgt ttaagaaaga aaatttaaaa caacgttatt
     5641 ttaattttgg attagtagcg ttagctctaa caatattagc catcattttt gccttctcaa
     5701 gtaaaaatgc tgatactaag tcttatgcta agaagtcaga aagtaaaatg gtaacaatcg
     5761 acaaggctcc aaaaaataat catgctatta ctaaagaaga aagcaaagat aaatcaaaga
     5821 gcattgcttc ggagcctatt cccacagtag aaaactctgt agctccgaca gtaacagagg
     5881 aagcaccggt tgttcagcaa gaagtgactc aaactgttca gcaggtatct tcagtagcct
     5941 ataatccaaa caatgtggta ctttccaatg gaaatactgc tggtattgta ggaagtcaag
     6001 cggcggcaca gatggcagca gcaacaggtg ttccacaatc aacttgggaa catataattg
     6061 cgcgtgaatc taatggaaat cctaacgcag ctaatgcttc tggggcatca gggttgttcc
     6121 agacaatgcc aggttggggt tctacagcaa cggttgaaga tcaagtcaat gcagccttga
     6181 aagcctatag tgcacaaggt ttatcagctt ggggttacta aataaacata gctggaagaa
     6241 ataaaaccta ttgttagtat ttactaacaa taggtttttg gtatttaatt gtctttatga
     6301 tttgtagtga tgaattagtc tcaaaacaaa acattgcctt atcagggaat atagctcgta
     6361 ttatttagga aaactgacca gcacttaagt gcctctgata tttaaggcag ttatactgat
     6421 aacaagcagg aaaaaaactc ttaaatgttt ataagatcat tagcaatttt cagtatttta
     6481 cactactaca cttttgagtt ttaacaattt actagaagtt gtttctaagg ggaaacaaca
     6541 tagcttgata gctatctatt agtcatttta gtgaatatat agcagaaaaa taaaacgctt
     6601 tcaaatattt ctaagaattt ttctaactat ctatttattc gccaaatatt tctacgctgt
     6661 aacgtcgtcc agttggagta gcggctaaac caccttctgc tgtttcacgg aaagcagttg
     6721 gcatggcaga gccgacttga tacatagcat caataacttc gtcaacagga atttgagaat
     6781 caatatcagc taaagccata tcagctgcga caagggcgaa acttgctcct agggcattgc
     6841 gtttgacaca aggcacttct actaggccgg caacaggatc acagacaagt cctaataaat
     6901 ttttgataac aaacgcaata gcttgactag cttgatgaga tgttccacca gctgctttaa
     6961 caagagcagc tgcactcata gcagctgcag aaccaacttc tgcttggcat ccaccttctg
     7021 caccagaaat agaggcgtta tttccaataa caagaccaaa agctcctgca gtaaataaaa
     7081 actctaattg ttctttttct gataagtcaa gtttttcaat agctgttgcg agcactgctg
     7141 gtaagcatcc tgcacttcct gcagtgggtg ttgcacagac aagtcccatt ttagcattta
     7201 attcgtttac agctatagca tttctaacag cattaagaat agtagtatca gaaaggctgt
     7261 tccctttttt aatgtagtta tccattttga ccgcatcgcc ccctgtcaaa ccactgatag
     7321 atttggttga ggttagtcct tctgttacag ctgctttcat aacttgtaaa ttgcgtgaca
     7381 tgattttgat aatatcttct cgatttcttc cagacatctc cacttccgtg gcaatcatga
     7441 gttcagcaat atttccatta aattgttggt cagcttgttt gacaagttct tcaatagtat
     7501 aaaacatagc tttcctttct agtcaaagaa gttgacatta taaatatgag gaatttttgc
     7561 aatttggttg gctgcttctt ggcactctct agaatcgact tctataatca tagtagcttt
     7621 ttcaccagcg gattcacgtg taacattcat tgtggcgata ttaatattat tggaagatag
     7681 gatatcagtt acctttgcga tcattccggg aatatctttg tgtacagtaa ctatagtagg
     7741 ggtattcatg gataacgaga cagaaaaacc atttagttct gttacttgaa tgtttcctcc
     7801 tccaattgaa acaccagtaa cactaagtgt tttgtcagct tttttgacac tgattttaac
     7861 agtattggga tggggagcat tactatcttt taagatatcc caatagattt ttatcccttt
     7921 ttgatgagca atttctagag aatttttaat atcaggatta tcagtatcca tacccataat
     7981 tcctgcaaca agagccttat cagtaccatg tcctctgtag gttttagcaa atgaattata
     8041 aaggtgaaac gtcacttcat caggaatatc tccaaagatg gaatggacta ccttaccaat
     8101 tctgacggca ccagctgtgt gactacttga tggaccaatc attactggcc caatgatgtc
     8161 aaaaactgat tgaaattttt gtgtattcat aggcaactcc gttttttatt tctat
//
LOCUS       DAUNLR010000064         8000 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUNLR010000064 DAUNLR010000000
VERSION     DAUNLR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8000
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.064"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            211..834
                     /locus_tag="VLL59_001566"
     CDS             211..834
                     /locus_tag="VLL59_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HER6509679.1"
                     /translation="MTIEIFNVTKKFSSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDNGKVLVDEQDIWKIKERTFFKNIIGYVFQNYSLIENKTVYDNLKLIN
                     KDKKKISAVLEKVGLSSDYLNQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDFIIDMKDIGSKK"
     gene            831..1322
                     /locus_tag="VLL59_001567"
     CDS             831..1322
                     /locus_tag="VLL59_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509680.1"
                     /translation="MKKKIYIGLIVIVGVFVVFLSGKQITQKETSNKPVVTLTVYTIS
                     SSDTQKWSKVKQFETKEAIYLVKVKETTSSEEVFSNIIADGMAVGFGVSEEDVKQFND
                     NLCSPVEDAKNNKLIGIEFINFSSVDKGVVVANFDYGKKAFNSQKTENKKLYKKLYEA
                     YKG"
     gene            1526..2056
                     /locus_tag="VLL59_001568"
     CDS             1526..2056
                     /locus_tag="VLL59_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HER6509681.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            2105..2692
                     /locus_tag="VLL59_001569"
     CDS             2105..2692
                     /locus_tag="VLL59_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HER6509682.1"
                     /translation="MQHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKITAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            2844..3572
                     /locus_tag="VLL59_001570"
     CDS             2844..3572
                     /locus_tag="VLL59_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HER6509683.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     EIAVKILDRLRKHDPQSLDFLMDISLSMKNQKAWKKRFITLIVCLTVETLLFVGGAYF
                     LQLTVWKYLLIPVFLLVLLGTLYWYYQNICYLCPSCHRTFEAKWTEFALAGHTPRTRK
                     LTCSHCHQKSYCLELAKEDTVSRG"
     gene            complement(3629..3928)
                     /locus_tag="VLL59_001571"
     CDS             complement(3629..3928)
                     /locus_tag="VLL59_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HER6509684.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(4121..4495)
                     /locus_tag="VLL59_001572"
     CDS             complement(4121..4495)
                     /locus_tag="VLL59_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509685.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            4665..4886
                     /locus_tag="VLL59_001573"
     CDS             4665..4886
                     /locus_tag="VLL59_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509686.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(4966..7248)
                     /locus_tag="VLL59_001574"
     CDS             complement(4966..7248)
                     /locus_tag="VLL59_001574"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HER6509687.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSIIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(7270..7929)
                     /locus_tag="VLL59_001575"
     CDS             complement(7270..7929)
                     /locus_tag="VLL59_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HER6509688.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
BASE COUNT         2605 a         1360 c         1568 g         2467 t
ORIGIN      
        1 aggcctctca aaaacacgca tagcaatttc gagtctcaaa tattttatta tgactattgc
       61 aatagttata atatgtacat ttatggtgac agagcagatt gagttattat atattggtat
      121 tgcttcatta gtggttttaa ttctttcgac agtaatgagt tttagaaaat tatcaaaaaa
      181 atacactcaa attttaaaag gagatgaaca atgacaattg aaattttcaa cgttacaaaa
      241 aaattcagct caaaaaaaat atttacagat ttaaatttaa cgtttgaagc tggaaaaagc
      301 tatgccttga ttggaggttc tggctctggt aaaagtactc tgcttaacat tataggaaga
      361 ctagaaaaaa ttgataacgg gaaagtttta gttgacgaac aagatatttg gaaaataaaa
      421 gaaagaactt tctttaaaaa tattatcggg tatgtattcc agaattattc tttaatagaa
      481 aacaaaactg tatatgataa tttgaaactc atcaataaag acaaaaaaaa aatatctgct
      541 gtacttgaaa aagtagggct ctctagtgac tatttaaatc aaaaaatata tgaattgtct
      601 ggagggcagg ctcagcgtgt agctattgca agaatgttaa tgaagccacg taaaataatt
      661 ttagcagatg agccaacagg agctttggat ggtgaaattg gaaaagaaat tattaatttg
      721 ttgttgagcg aaacagccga aaataaatac gttattatag caactcatga tccagctgta
      781 tataataagg ttgattttat aattgatatg aaagatatag ggagtaagaa atgaaaaaga
      841 aaatttatat tggcttgatt gtcattgttg gagtttttgt agtgttcttg tctggaaaac
      901 aaatcacaca aaaagaaact tcaaataagc ctgtggtgac cctaacagtt tataccatct
      961 cctctagtga tacccaaaaa tggagtaaag taaagcagtt tgaaacgaaa gaagcaatat
     1021 acctagtaaa ggtaaaagaa actacctctt cagaagaagt cttttcaaac atcattgcag
     1081 atggaatggc agttggtttt ggagttagtg aagaagacgt taaacagttt aacgataatt
     1141 tatgtagccc ggtagaagat gctaagaata ataaattaat tggaatagaa ttcatcaatt
     1201 tttctagtgt tgataagggg gttgtggttg caaattttga ctacggcaaa aaagcgttta
     1261 attctcagaa aacagaaaat aaaaaattat ataaaaagct ctatgaagcg tataaaggat
     1321 agctatttat agtttcttga gagtgatacc acttctgaat aataaatgaa ctaacttggc
     1381 ataccgtttt ctattcatct aacaatgttt tcaagaaata attgatgcct ttagcacgac
     1441 tgaaatgagg tcaaattgac agaatactcc tattatggta ctatttttaa taagaatatt
     1501 cagtgatagt gataaagagg aaaatatggg aattgaaaag acagttagtg aactagctga
     1561 tattttggga gtgagtcgtc aggccgtcaa taatcgtgtt aagtctttac ccgaagaaga
     1621 tcttgacaaa aatgaaaaag gcgttactgt ggttaagcgc agtggtcttg ttaagctgga
     1681 agagatctat aaaaaaacaa tttttgacga tgagcctatc agtgaagaaa cgaaacaacg
     1741 tgagctttta gagattcttg tggatgagaa gaacactgaa atcacgcgcc tttatgagca
     1801 actcaaagcc aaagatgctc aacttgcctc aaaagatgag caaatgcgtg ttaaagacgt
     1861 gcagatcgct gaaaaagata aacaattgga tcagcagcaa caattaactg ctaaagccat
     1921 ggctgataaa gaaaccctaa aactagaatt ggaagaagct aaagcagaag ccaaccaagc
     1981 tcgcttacaa gtcgaagaag ttcaggctga agttggccct aaaaaaggct ttttaacccg
     2041 cttgtttgcg aaataatcac aaaaaatgac gaaggcccta tcagggtctt ttttggagga
     2101 aaacatgcaa cacttagata cttatattgc ctttgattta gaatttaaca ctgtcaatga
     2161 cgttagtcat gtcattcaag tatcagcagt caaatatgac caccataaag aagttgacag
     2221 ctttgacacc tatgtttaca cggatgttcc cttacagagc tttatcaatg gcctaacagg
     2281 aatcacatct gacaagatta ctgcggcacc aaaagtagag gaggttatgg ctgcgtttaa
     2341 aaattttgtg ggagagttac cactgattgg ttataatgct caaaaatctg acctgcctat
     2401 tctagctgaa aatggcttgg atttaaggga ccaataccag attgacctct ttgatgaagc
     2461 ttacgataga cgtagcgcag acttaaatgg gattgctaac cttcgtctgc aaacagtggc
     2521 aaccttttta ggcattaagg gtcgaggtca taatagctta gaagatgcca gaatgacagc
     2581 agcaatctat aagtcttttt tagaaacaga tacaaacaaa gcatatctca gccagcaaga
     2641 agaggtaacc acagataacc ctttcgcagc tttgggagac tttttcgact aaaggctctg
     2701 ctatttttga aaaataaaaa aatccctagg gttagccctt gcttgtaacg ctaggtcatg
     2761 tgataagcta ggggcatatc aagagggagt cgggtgcaca cgagtcgctt ttgatcacta
     2821 aatgatagaa agaaggtgtg gaaatgtctc aattctattc gactggagaa ttggccaact
     2881 tagctggcgt ttctattcga actgtccaat actatgacca acgtgggatt ttgattccga
     2941 cagcattgac agcaggtgga cggcgactct atacggattc tgatttagaa caattacgca
     3001 tgatttgctt tctgcgcgat ttgggatttt ccattgagca gattcgcaaa gtcttagcag
     3061 aggaaaatgc agcccaggtg ctggaattgc ttctagttga tcatattgcg actgccaagg
     3121 aagacttggc cgcaaaagag caacaagttg aaatagctgt caagatactt gacagacttc
     3181 gaaaacatga cccccagtca ctagattttc tgatggacat ttcgcttagc atgaaaaatc
     3241 aaaaagcttg gaaaaaacgc tttattactt taattgtctg tttgacagta gaaactctac
     3301 tttttgtggg tggagcctat tttctccaat tgacagtctg gaaatattta ttaatcccgg
     3361 tgttcctttt agtcttacta ggaaccttat attggtatta ccaaaatatc tgttatcttt
     3421 gtccttcttg tcatcgaaca tttgaagcaa aatggacaga atttgccctt gcaggccata
     3481 caccacgaac cagaaagtta acctgctccc attgccatca aaaatcgtat tgcttggaac
     3541 tggcaaaaga ggacactgtc tcaagaggat aagcactaac tcataaaaaa actagcctga
     3601 gatccttctc aagctagttt ttgttttttt agaatggtaa tttaccagca aaagcgccta
     3661 atgttttctt agttgcttca tcaatttgcg taagggcatc attaatggct tgagtggtca
     3721 tgtcttgaag cgtttctaca tcttcaggat ctacaacagc ttctttgaag tcaatcccaa
     3781 ccaatttttt atcacccgtg aaagtggcag tgacaaggtc ttgagctgat tttccagtaa
     3841 attgcatagc agccaaatcc gcctgctttt gctccatttg tttctgaagc ttttgtgctt
     3901 gcttcatcat gttttgcatg ttcatcataa gactatactc tccttaattt aatactaact
     3961 attataacac ataaaaagag gcaataaaaa caatgtcagt tagtagacta gcctgtatca
     4021 gtaagaaagt cgctatggat aagatggatt agcagcaagg gtctggctaa tgacagaata
     4081 agtctagaaa tggactattt ttgtcataga ctagtccgac ttagtggtta tctaattcac
     4141 gatcttcttt agcttgttgt tctaaaagaa tttgtgcgaa gtcaacccac ttagtgtagt
     4201 tattttcgga taattgttct gaaatcatcg ctaactctcg ttgtggcaac tgataagaga
     4261 ctcccttact ttctaaggtt aaatcttctt ccattagggc ggttaaacta acatcaaaga
     4321 tagcagcaat atcacttaat agaccagatt ttggagtata ttttcctttt tcccactcac
     4381 tgattgaaga agagcttttt cgtcctagga gattagcaag ttctaattgt tccatgttct
     4441 tttttaatct aaggtacttt aaattacttg caaaaaaagt tttcttggcg gacatatttt
     4501 tctccttttc tttatataaa atatgatacc ataaaagagg ttaaagcaaa aggtatcgta
     4561 aaagatggtc taaaaactct ctaaaaactt gacttcataa aaaccgaagt ttataataaa
     4621 cttaacatga ttaactaatc tcattttagt gtggagggaa aattgtgacc aaatcaactt
     4681 taaaagagtt aagaacaaca aagaaaatga cacagcagga attgtctcac ttaacaggca
     4741 tttctgtcag aacgattgct aggtatgaaa aagatactaa aaagctaagg cgagcaaaat
     4801 atgagaagct aaaaggtatt gcacaagcat tagcggtttc cgttgatgat atttttttag
     4861 gaatagattc ggaatttatg aactgagacg atcgttttct gtttgctatt agtaagacca
     4921 attaacaaaa aagtgcttag ttatattgct aagcactttt ctttgttaat ttgatgctat
     4981 tggcacaatc aattgagact gactgagatc gatagttaaa gcatagttgc tgttgtcacg
     5041 gacagtatgt tcaaaatcgg ttgtgtataa gatgactcga agggtatctc ctttttctag
     5101 atgatagata gttggttgca aaggaagtct aacagtcatc catttattat taggaatagt
     5161 ttcaattgac gacaaattat tgcgattttg taaattcatg aaacctttcg aaataacacg
     5221 gtaagaatct tctctaaatg gtagctcttt aaggggttct ctagagaaat tttgcccatt
     5281 gtcaatactt gattgggtga gagcaatagg aagatcgccc aagcgttttt tcttaccata
     5341 gtcaaggatt tgtgcagata gaagtccttt attttcgctt gatttcactt ttaactgtag
     5401 gacaatttca ccgttaatag gtaagtcctc ttccagtaaa atatcaatca gggcttgatt
     5461 ggccttgcct ttaaagagag ctgctttgaa cgcacggaaa tctttaccgt aagctttaaa
     5521 ttcatcttca ccatagtgat tatcaattaa aagcagttcc tgaccgaggt caagctcttt
     5581 gatgattgag gttccaaaga ctttacgctc ttgccagttt tgtgggcagg tgttatcctg
     5641 ccagatcatt tcaggaaggc taaaatcatt agctaggcct aagagttttt gacataaaag
     5701 ggcattcata ctttcgcgaa aatcaatgga ttgccaatta tgcatgtaaa catgctcacc
     5761 ttgatgtaaa aagaggtgct tgttgattgt ggaaggaagc gcattgaaaa tctcatagac
     5821 ctgtcttggt ttgacattcc agtcttgtaa gccatgagta taaacgacat cacactttat
     5881 ttgatgagca ttttttaagt aattgcggtc gtgccaaaat tgattataat caccagattg
     5941 tcggtctaac gcctgagact gttggtttag caattcttga taacgatcat tatggcgaag
     6001 ataatcgcca gccaataaat tacgcgagta agtgagctca gttaggacat ctagatcctc
     6061 tccaggatag ccaccaggac tacaaactaa gccattttcg cggtagtagt tgtaccaaga
     6121 agaaatagct gattctgcaa taatcatggc taatccgtct acgcctgtag tggctaaacc
     6181 agtagacata gttcccaagt aggactttcc agtcgtacaa actagaccat ttgcccaatc
     6241 agctctcact tggtgggttt ttgagtggct ggtgtaggct gtggctcttc catttagcca
     6301 atcaataacg gctttaaagc tttcaatttg agcatagtct ccactcgtca taaagccagt
     6361 ggaaccagca gttcccacac ctgaaacata gatattagca aacccacgtg cgaggaaata
     6421 atcgttgagg ctataggagt taatgtagct aaagctttct agattttgac ctataggaag
     6481 tttgcaaggc tgtgtctcaa gaggaataaa atccctgtct tcgacagtga tttgtctcct
     6541 ttttttaacg actaactctt tttccatacg ataaagtttt ttgtcgttgg ctacttcatt
     6601 gataccttga tggtatggac taggtgtcat caaagttggt aatggttttt gagattgagg
     6661 acgaatgata ttaaccttaa taagatcaag ttggccatct tgatcggtat caagaggtgc
     6721 ttcaacgtaa acaacttctc gaatcagctg tgacgtgtca aaggtagcta atgatttacc
     6781 gttgaagaag tggtaatcat tgtccatagt aagcattcct tggctgacca aatcatcaat
     6841 cagggtcatg ccagacttac aacgggtcgc taataagtgg tggatatgct tgataatttc
     6901 tgtttcgtca aagtggatag gaaaggccag tttatcaagg aaagcatcgg cctctgtaaa
     6961 atcaactcca ggaataaagc caaggacttg cagggccagt aaatcaaaaa cctctttgga
     7021 taactcttgc tctgattgaa aaaagctcaa tgcgtccatg tcatttttgg cgattagatg
     7081 acttaaagga taatcactgt cagggtagtg gaagaagagt ttacgtaaaa agctttctag
     7141 gttagctttg gcagtttttt gcagatccag atcaaagccc aattctttta attcttcagc
     7201 cgctctttct agactagttg gaatatagga aaattgatta tagcgcatag gagtttcctt
     7261 tctaatggct tagaaaacga tattatcttt taatttgtca agattggtaa tgataatatg
     7321 ttgtttatca atgcgaatga tgtttttttc tttcaactgt tttagaatac ggctgacgct
     7381 gctagcggta gaaatgccac agaatttacc gagttcctca ttagtaatga caaaattaat
     7441 taaaatctgg ccatttggta gttcttcgcc aaataaggtc attaagtcat atatttgagt
     7501 agaaatggca ccgatacggc cgttagttaa catacattgc atttttttca tggatttttg
     7561 aagacgatta tggtaaaagt ccttcacata tccttgtagt tcaatatctt cgtttatatc
     7621 ttttaaaaat gctgagcggc gaaccttgta aaaactagct ttctctgact cgatgcgaac
     7681 attataaggc tctcccatat cttttgaata accagtgttg agaacagaag taatttcaag
     7741 tcctgtaaca tatctcaaat taaattccat tccatatttt gaaagaacac tctgtttcac
     7801 aatgccgtct tttaaaatat aagtgaagtc ctcttcgaga ctttcaaaag tcaagtactt
     7861 gtgataactt ttttcaatga taggaaagtt atgattatca atataccgtt gcaaaatgtg
     7921 atgattcacg cttttctcca aatattcttt taccaatgta taatttgtat cttcaagaga
     7981 aattaacatt tgctaatgcc
//
LOCUS       DAUNLR010000065         7544 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUNLR010000065 DAUNLR010000000
VERSION     DAUNLR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7544
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.065"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(60..3236)
                     /gene="carB"
                     /locus_tag="VLL59_001576"
     CDS             complement(60..3236)
                     /gene="carB"
                     /locus_tag="VLL59_001576"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HER6509689.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPTLDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQDLQMHVEHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            complement(3482..4564)
                     /gene="carA"
                     /locus_tag="VLL59_001577"
     CDS             complement(3482..4564)
                     /gene="carA"
                     /locus_tag="VLL59_001577"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HER6509690.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            complement(4608..5543)
                     /locus_tag="VLL59_001578"
     CDS             complement(4608..5543)
                     /locus_tag="VLL59_001578"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HER6509691.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRAAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            complement(5604..6863)
                     /locus_tag="VLL59_001579"
     CDS             complement(5604..6863)
                     /locus_tag="VLL59_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HER6509692.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYVAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            complement(6879..7400)
                     /gene="pyrR"
                     /locus_tag="VLL59_001580"
     CDS             complement(6879..7400)
                     /gene="pyrR"
                     /locus_tag="VLL59_001580"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HER6509693.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
BASE COUNT         2332 a         1636 c         1261 g         2315 t
ORIGIN      
        1 tgtcattata atctaaaaaa atcattttta agttttctta aaaatgattt ttttaatttt
       61 tatatcgctt cgatgttaaa gcatctgctt tctaaaaccg ttaacatagc ttttgcagta
      121 tctaaagctg taaataaagg aactccttgt tcaatagctg aacttctaat catctgtccg
      181 tctttatcag ctgtgcgttt aattccaact gtattaacaa ttgcctgaac gtgaccatgt
      241 cgcacgagtg tcgggatgtc attggcagca tcaccaattt ttccaactaa acacgcgctt
      301 aagccttgct cagcaaagta agctgctgta ccttgagtag ccataatttg atagccaatc
      361 gccttaaatc gtcttgctag acttagagct tctgccttac tatcatctgc tatagtaaag
      421 acaatttgac caaattctga taaatgagaa ttattggctt caaacgcttt ataaagtgct
      481 ttttcaagac tagtatccga acccattact tctccagttg atttcatttc aggacctaaa
      541 agactatcaa cctgtgccaa ctttgtaaat gaaaacacag gcgctttgat atgcaccagt
      601 tgactttggg gataaagacc atcttcatat cctagatcct ttaatgtttg acctaaaatc
      661 aacttagtag caatctgagc catcggaata cctgttactt ttgataagaa aggcacggta
      721 cgactagcgc gtggattcac ttcaataaca tagacttgtt catttttaat aacaaattga
      781 acattcatca taccaataca atttaaccca atggctaaac gtttagtata ctcagctatt
      841 gtttcttgaa tttgcttaga taattgctgt ggcggataaa ctgccattga atctcctgaa
      901 tgaacacctg ctctttcgat gtgctccata ataccaggaa ttaagactga ttttccatct
      961 gaaatggcat ccacttcaca ctccttaccg aaaatataag agtccactaa gataggatgt
     1021 tcaggacttg ctttaaccgc tgttcttata tattctctaa gatcttcttt gttttcaaca
     1081 atttccatag cccggccacc aagtacgtaa gaaggtctaa ctaagactgg aaaaccaatt
     1141 tttttagctg cctctaaagc ttcttcttca ttagttgccg tttgaccttg tggttgtggg
     1201 attccaagct ctttcaacgc cttttcaaat aaatctctgt cttcagccct atccaaatcc
     1261 tctacttgtg ttcctaatat tgtaacaccc gcctcagaaa gtgcttgtgc taagttaata
     1321 gcagtttgtc ctccaaactg aactattact cccttaggct gctctaaatc tatcacattc
     1381 atgacgtctt caaaggttaa cggttcaaaa tataatttat ctgataccga aaaatctgta
     1441 gatacagtct ccggatttga attcatgata atggcttcat agccagcttt ttggatggct
     1501 ttaacagaat gaaccgttgc gtagtcaaat tcaacccctt gaccaatacg aatagggcct
     1561 gaacctaaaa ctaaaattga ttctttattc gactgaacag attcattttc caactcatat
     1621 gttgaataaa aataaggggt tttagcatca aattcagctg cacaagtatc taccatttta
     1681 tagacaggat acaggctatg agaatgtctc atcgctctga tatcactttc atccttttgc
     1741 caaatttctg caattttttg atctgaaaat ccataacgct ttgctttttt gaggctttcc
     1801 aaatgctcaa catgcatttg tagatcttgc tctatttcaa caatatgaag taatttatcc
     1861 aagaaaaata aatcaatctt ggtcaagctc tcaagttctt cgatactata acctcgtcgt
     1921 attgcttctg acaagtaaaa aagtcgatca tcttgagctt taatcacttt agtcactaac
     1981 tcttcatcac taatgttact taaacttgtc atctcattat ggcaaacacc aatttctaaa
     2041 gaacgacagg cttttagtaa ggactcttcc aaattacggc caatagccat gacttcacct
     2101 gttgctttca tttgagttcc cagttggcgt tcaccatgtt caaatttgtc aaacggaaaa
     2161 cgcggaattt tagcaacaac gtaatcaagg gtaggttcaa acatagcgta agtagtgcct
     2221 gtgatagggt taatcatttc atcaagtgtt aggccaacag caatctttgc agccaatttg
     2281 gcaatgggat aacctgttgc ttttgaagca agggcagagg aacgagacac tctaggattt
     2341 acttcaataa cataatattt gaaactataa ggatctagtg ctaactggac gttacagcca
     2401 ccttcaattt tcagagctcg aattattttt aaactagcat cacgtaacat ttgattttca
     2461 atatcagaaa gggtctgtgt tggtgcaaat acaatagaat ctcctgtgtg aatccctacg
     2521 ggatcaaagt tttccatatt acaaacaacc agcgcgttat cagcactatc tcgcattact
     2581 tcgtattcaa tttctttgaa gccagcaatt gagcgttcaa tcaaacactg tgtgaccggt
     2641 gataacttta ggccgttttc agtaatttca caaagttctt cttcactact acatattcct
     2701 ccaccagttc caccaagagt aaaagctggg cgcacaatga ctggataacc gatatctcta
     2761 gcaaatgtaa cagcttcatc aactgtttta acaattgtag attctggaat gggttggtct
     2821 agttcttgca ttaattgttt gaaaaggtct ctgtcttctg cctgatcaat cgcagataac
     2881 ttagtaccta acaattcaat ctctaaatca tcaagaatac cagctttaga taatgccatt
     2941 gccatattga ggcccgtttg accacctaag gttggcagta tggcatctgg cctttctttt
     3001 cgaatgatac gattaacaaa ttcaagagtc aaaggctcaa tatatacctt atcagcgatt
     3061 tctttatctg tcataatcgt tgcaggattt gaattaacaa gtatgacctt atagccttct
     3121 tcttttagag ccaaacaggc ctgagtccct gcataatcaa attcagcagc ttgtccaata
     3181 ataatcgggc cagacccgat aaccatgatt ttttgaatat cttttcgttt tggcataatt
     3241 aatgatacca agaataccac aagaagcggt aaagtcagca cttctcaata agagctttat
     3301 ctctttgaaa acctaacttt ttactaaatt atttacttgt gttctccttg ccttcctttc
     3361 tctatttgtt gcctcacaga gcaacattaa ataatatttt tgatagggta ctaaatcaac
     3421 tgtaaatgtt aataaataga gtaacaagag gtgatatagt cgtgaaattg caactgattt
     3481 actatttact cgtacatctc caagaatcaa tcatttccaa aaattcgtca aataagtagc
     3541 tggcatcatg aggtcctgga gccgcatcag ggtgaaattg gactgaaaaa gctggaaaat
     3601 ctctatgttt cactccttcg accgtcttat cgttaatgtc ttcatgcgta accattaaag
     3661 tatcaggtag actactacgt tcaacggcat aaccatggtt ttgactggta aaatcaattc
     3721 ttcccgttgc aatttctcta acggcatggt taaagccacg atgaccaaag gtcattttac
     3781 aagtcttggc accatttgct agactaaaga gttgatgtcc catacaaata ccaaaaatag
     3841 gaatcttacc ttgtacccca cgaatcatgt ctaaagcctc tggcaaatct tctgggtttc
     3901 ctgggccatt agatagcatc aagccatccg gatttagttg gagcacttct tctgcagtga
     3961 tgttgaaagg gacaacggtg atattacatt gtcttttaga aaattctctt aaaatagaat
     4021 gttttaaacc aaaatcaacc aatacaatat ttttcccgat ccctggtgca ggataagctg
     4081 ttttagttga cacttgttca atggtgttag tcggtaagac tgttgcacgc agttgatctt
     4141 ttaaatgctg gatactatct ccatcatctg ccatcgtagc tttcatggta ccgtgttgcc
     4201 gaataatttt ggtcaaagct ctcgtatcaa ttcccgaaat ccctggaatc ccttttattt
     4261 tcaagaacgc atctagcgtc atttgcttgc gccaattact tgccaaccga ctgacttcag
     4321 acacaacaac ccctttacag gtgggtgaaa tggactcata gtcatctcga ttaatcccat
     4381 aatttccaat caaaggatag gtaaaggtta aaatttgccc attgtaggat tggtcagtga
     4441 tggattcttg gtagcctgtc attcctgtat taaagacaat ttcaccagtc acatcaatat
     4501 cagcaccaaa gggttctcct tcaaaaatag tgccgtcttc taaaataagt aatcgttttg
     4561 tcattttcct accttttcct accttctaaa catgctttaa tctttcatca tgagttttta
     4621 tttctaccat tcaaaatggc ttcaataata gccatgcgaa caaagacacc attagccatc
     4681 tgagatacaa ttctcgcttt aggagcttcc accaaactat ctgcaatttc cacatcccga
     4741 ttaactggag ctggatgcat aataatagca gaatctttta attgttggta acgttcctgt
     4801 gtcaatccaa acgcttgatg gtaaccttct tttgaaaaac tctgatggcc gtcatgacgt
     4861 tcgtgctgta cacgcagcaa cataagaaca tccaattcct taataatctg gtcaatagca
     4921 atataagtgc cgtaagcatt aaaggcttct gaataccatt cttcaggtcc atagaaataa
     4981 agctctgctc ctaatctttt gaggatttgc atgttggact ttgccgccct agagtgagtt
     5041 aagtcaccag cgatcgcaat ctttaagcct tcaaagcgtc caaattcttc atagatggtt
     5101 aataagtcaa gtaaacattg actcgggtgt tgtccagaac catctcctcc attgacaatg
     5161 gaagctgtaa tagttggact ttctactaat tccttgtaat aatcatcttc tgggtgacga
     5221 atcacacaga tgtctgttcc aagtgcactc atggttaaca cagtatcata caaactttct
     5281 cccttgttaa ccgcacttgc atcagcattg aaatcaagaa ctgtcaagcc gagtttcttc
     5341 tcagccactt caaaagactt atgggttcgg gtggagtttt caaagaataa attggcaaca
     5401 agatcctttt gatgatccga aataacaacc ttaccagcct tatattctga accacggttg
     5461 ataagaccta aaacttcttc ggtggttaat gcttccattg aaactaaatt ggtaagtgca
     5521 acgcgattat ttacaactga catgattatc ccctttatca ctaacgactg atgactatgt
     5581 aagtggtcta acaacaattc ttcctatttt tcaggaagta cctgatataa gatgatgcca
     5641 agaagtgttg agaaagcgac acctgaaatt tgaagaccat ttacttgaag catcaatcct
     5701 ccaatcccag agaccaaaat gacactggca atcaataagt ttttcttatt atccatatca
     5761 actttggatt caatcaagat tttcaaaccg ctagaagcta tcacaccaaa caaggcaact
     5821 gatatacctc caataactgg tgttggaata gattgaatta aggctgatac cttaccgata
     5881 aaactgagga gagcggcaat cactgcggca cctgcaataa catagaccga gaatatttta
     5941 ttcagagcca ttacaccgat gttttcacca taagaagtga ccggaggtgc tcctaagaag
     6001 ccggcaatga tttgcgcaaa accatcacca gttaaagtct tttcaagtcc tggatccttg
     6061 aaataatctc tttttgtcaa actatttaag accataatgt gtccaaaatg ttctgtcatt
     6121 gtaacaaagg caatgggtgc catagttaaa atggcacttg ggtagaattt aaccccgtag
     6181 gttaagaaag gaatttccac tgatgggata ctaaaccatt tggcctgagc cacattggta
     6241 aaatcaacaa tttcttgacc ggtgagaaca cccactaaaa gggctacaac ataaccaact
     6301 aatagcccta ataaaagcgg tacaatagca acaattccct taccataaat attgaaaaaa
     6361 ataactgata ataaggtgac taacccaata acaagataag tcagattata gttcccattt
     6421 tttagcatga catcattaac agctgtagaa gctaggctta gaccaatgac cataacaatc
     6481 ggaccaacca caatcggtgg taagatgtta tcaatccaat cattgccaat agctttaaca
     6541 atcaaagcta caatcaggta aacgagacct cctgtcatag ccccttgagc tacagcacca
     6601 ataccatttg tcttcatcag taactgcata gctgctacat aagcaaaact tgagcccatg
     6661 taggctggaa ttttaaattt ggtcactgat aagtgggcaa gggttcctaa accactagat
     6721 aacaaagcaa ctgatgggtc aattccaact agaatgggaa ccagaacagt cgcaccaaac
     6781 atagcaaata agtgctgaaa ggacaaacca actaacatac ctgcctttgg cacttcttcc
     6841 acatcataaa tgacatcttt cacagtaaaa cctctttctt atgttgggtc aataatgcta
     6901 acacgatcac ggccatcgac ttcgacaacc tcaacaacaa tttcttctac actgcttgtt
     6961 ggaatatttt tcccaacgta atccgcgcga atcggtaatt cccgatggcc acgatccacc
     7021 aaaacagcta gactaacacg ggctggtcga cctaaactca ctaagttatc gatggctgcg
     7081 cggatggtac gaccagtata aagcacatca tcaatcaaaa tcacatcctt gcctgtaata
     7141 tctactgaca tgagagttgt gtcttcctca actctcatgt catctctaaa aggcttgatg
     7201 tctaactcac caattggtaa atccaaccct tctaattgat gcagtctttc ttgaatgcga
     7261 cgagctagaa aaacacctct cgttttgatg cctgccaaaa ccacattgtc taattgttta
     7321 ttacgttcaa taatttcata agtaatacgg gtaatggcgc gtttcatggt cacgtcatca
     7381 acaatttcct tagttttcat gttgaaacct cctctaaaaa ttcaaataaa aagatctcct
     7441 tggaaacaag gagattcagc aaaatatagc acaattaagt atcatgatgc atgtttttaa
     7501 tccgtctcct tgacagcctc acaggactgt tttaaaggaa tatt
//
LOCUS       DAUNLR010000066         7532 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUNLR010000066 DAUNLR010000000
VERSION     DAUNLR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7532
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.066"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(77..286)
                     /locus_tag="VLL59_001581"
     CDS             complement(77..286)
                     /locus_tag="VLL59_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509694.1"
                     /translation="MRFSYNKLWELLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLKICIALDCKIEDIVEIVDNNI"
     gene            complement(276..1120)
                     /locus_tag="VLL59_001582"
                     /pseudo
     CDS             complement(276..1120)
                     /locus_tag="VLL59_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017502.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
     gene            complement(1205..1933)
                     /locus_tag="VLL59_001583"
     CDS             complement(1205..1933)
                     /locus_tag="VLL59_001583"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HER6509695.1"
                     /translation="MLIEMWSPVFKKHGEIREPICFHHGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARRYAFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDI"
     gene            complement(1924..2148)
                     /locus_tag="VLL59_001584"
     CDS             complement(1924..2148)
                     /locus_tag="VLL59_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509696.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSRNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            complement(2148..3041)
                     /locus_tag="VLL59_001585"
     CDS             complement(2148..3041)
                     /locus_tag="VLL59_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509697.1"
                     /translation="MTNMLDFPYHHEFIEFLGRWTHILITLPKRHHGQVDTAIPRYLL
                     VTIREKTGIVKLTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEALNLIALCPDGFLTYQADRRKKIVTTLKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYNISYDSKQLTDKISPENNRTLYQLVKNQVI
                     DNYLTIQKIIVNLDKQGKIDYEKIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHLATL
                     QDIYFCQMIVSYFIQKCEVLE"
     gene            3057..3233
                     /locus_tag="VLL59_001586"
     CDS             3057..3233
                     /locus_tag="VLL59_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HER6509698.1"
                     /translation="MGQNVVMRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCICRQG
                     DEASVYDERGILSF"
     gene            3288..3590
                     /locus_tag="VLL59_001587"
     CDS             3288..3590
                     /locus_tag="VLL59_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HER6509699.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLFQLKENA"
     gene            3590..3895
                     /locus_tag="VLL59_001588"
     CDS             3590..3895
                     /locus_tag="VLL59_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HER6509700.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADDLLERLSQGM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            3914..4186
                     /locus_tag="VLL59_001589"
     CDS             3914..4186
                     /locus_tag="VLL59_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509701.1"
                     /translation="MELVKTIQIGDDIYPPIPDLFGIQENQEFNLYKSTDGTLVLSPS
                     DSKLSADHQSISSDEQMTTAVEQARLDEIATSVLSRHLDAFKELTE"
     gene            4291..4743
                     /locus_tag="VLL59_001590"
     CDS             4291..4743
                     /locus_tag="VLL59_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HER6509702.1"
                     /translation="MGLLDLIGRKRARDKPQNSYEGQDFSYLFGRTTSGENVDEFKTM
                     QTTAVYACVRVLAEAVASLPIHIYERTENGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TIMSHLLIWGNAYVQIIRDKSGMVSLLLKQKASVLIRKLLLIIWQRMP"
     gene            4809..5123
                     /locus_tag="VLL59_001591"
     CDS             4809..5123
                     /locus_tag="VLL59_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509703.1"
                     /translation="MPRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNGNL
                     SIDTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVR
                     ID"
     gene            5540..5878
                     /locus_tag="VLL59_001592"
     CDS             5540..5878
                     /locus_tag="VLL59_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HER6509704.1"
                     /translation="MKPPFTVTNTMLNKVVEISKIIGNLELQVQKDLKLRKENRIQSI
                     HSSLAIEQNSLTVEQITAIIDGKRVLGNPREIREVKNAYEAYEEILTLTPYDESHFFK
                     MKKFQQYIYR"
     gene            5902..6726
                     /locus_tag="VLL59_001593"
     CDS             5902..6726
                     /locus_tag="VLL59_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine ligase"
                     /protein_id="HER6509705.1"
                     /translation="MGLGSDSLPVKISLFDVDTYLADSMQFHLEYILRLFPKSGVHYL
                     MPTFRGEAVDHRHLSQFYHSECEIEGDLHYVMNLVDRYIKFLVSEILRECRDSIFAIT
                     KDVSHLESFIDRKIPIITFEEACTILENEIDSLEYNDEHHFYVLTDVGEKKLMEHFEG
                     VVWVKNYPCKSVPFYQRFSTDHLFAYNADLLLGIGETVGCGERCETYEEVVENMNYLQ
                     VDASEYSWYLEMKKTRPMKSSGFGLGVERLIAWILKCDDVRKVQLISRENGIDYLP"
     gene            6740..>7532
                     /locus_tag="VLL59_001594"
     CDS             6740..>7532
                     /locus_tag="VLL59_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HER6509706.1"
                     /translation="MKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFV
                     ETIETSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSF
                     RFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNF
                     SELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIY
                     TPLGITKKIVDEKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQIL"
BASE COUNT         2389 a         1155 c         1551 g         2437 t
ORIGIN      
        1 aaattatttt tttcaaagta aaggcactaa gttgatctga cttacacatc ttatcaactc
       61 agtgcttttt ttatttctag atattattat ctacaatttc tactatatct tcaatcttac
      121 aatcaagtgc aatacaaatt ttcaataaaa tatcagtagt gatattttcc ccttttccca
      181 attttgcgat cgtggaagaa ctaatcccag cttcttgcct gagctttgtt ttggtccaac
      241 ctttatcaat aagaagttcc cataatttat tgtaactaaa tctcatctga gttttctcct
      301 ttgttccatg aaataccgta gagttcattt ccgttactag agagtctcaa taccgtattt
      361 tctgacaaga gttgattagc atctggagaa taagagctgg ctttatcgaa ggctaaaaag
      421 acttgtttgt tcaatgactt tgactggtca tacagcttca aaagtgcttc agtcgcttgg
      481 tagctaacat tactcaagag taatgaatcg tgtgcgagtg ctggcagatt agtaaggtag
      541 agcattacta agtcgaatac aatcatccct ttgaacttag ttcctgtacc atcatcatct
      601 ggtgtataga aggagtagct attgtgagca ttgaggttaa ttgaggagct ttgcgaatat
      661 ctggatatag aatgttattg aattcacgca tcttactgtt gatttttact tctagatcta
      721 gaaggatatc ttctgtactg cgtttcaagt cagcgtccgc ttctgatttt tctttggata
      781 gaccagactc ctttaagtag gcctcgtttt gttcttttag tgcattgatt gtagctgtta
      841 gtttagagta gttttctaag tactcacttg aaagatttgg gatgtttcct agttcttgaa
      901 gttcttggtt tagagttgtt aattgactct ctaattcgtc gatctcagct attagggatt
      961 cacgttcagt tgagaattcg gaatctaaaa tagtttccaa ttttttgtgg taagcttcaa
     1021 cttcatataa ttttttgaga ttagtatctg ggaagtattg ttgaagctct gttaagtcag
     1081 attcagtagg atataagcca aattcgatac tgatgtccaa tagcttaaga cgtctttgct
     1141 tgtcccgaag actgctttct aactccagct tagtatttct aagttggagt ttttgttgat
     1201 ttttttaaat atcatcagag tcaattttat cttgatgagt atcttggaga tgtgctaaat
     1261 catattccaa tctttttatt tctgagacat ttgcttcaaa ttgcttttta ccgccaacca
     1321 ggttggagat gaaggcatac ctgcgagcat tacgaaaagt tgttaactgg tcgctcttat
     1381 ctttcagacg ttctttgtat cgtgcaatgt tatcatacaa attaaacagt tggatgagag
     1441 tagtaataga ttcagaagat ttttggctcg aataaacttg taaggggaaa tcggtatttt
     1501 gattactttt tcctgcaatc ctaaagaagc cactcatagc taatcggaat gatagctctg
     1561 gagaatctaa atgatatcgt ttcttaagtt tgttaagaaa aattcctagg tccattgttt
     1621 caccggttgg agagtagctc ttgtcacaca ctagaatgat atctgggttg gccgtatctc
     1681 ttgaaaaata aaactttttc tcaaattgaa agcagaagta gataggatga tcacctaatt
     1741 ttttaaccgc aattgatttt agatagctat tacctccaaa gatgaaatca atggctaata
     1801 gtgaggagga tttgccgata gagttatcag ctaaatccat ccccataatc acgtttaacc
     1861 catggtggaa gcagattggt tcccgaattt ctccgtgttt cttaaatact ggagaccaca
     1921 tttctataag cataatttta cttctccttc attagacatt tcaatagcgt tcaatgcata
     1981 caagcaatcc attatggata gaaaatctgt aggatcatcc aactcttctg agatagcgtg
     2041 aaagatatct ttgacgtttg agtttctact tttgatttca tttagcactc taggcaaata
     2101 agcaagggtg cttttttgat aggagtaaag tttatttggt aattgcatta ttcaagtacc
     2161 tcgcattttt ggataaagta agagacaatc atctgacaga agtagatgtc ctgtagtgta
     2221 gccagatgga gtttttccga aatagtattg aaaatagcca gattattatg cttggctgct
     2281 tttaactttt tatacatcga tcgcgtttga tattggattt tctcgtaatc aatttttcct
     2341 tgtttgtcca aatttacgat gattttttga atggttaagt agttatcaat aacttggttt
     2401 ttaaccaatt gataaagcgt acgattgttc tcaggtgata tcttatcagt caattgcttc
     2461 gagtcatagg agatattata ttcatcacat tttagtttat tgagactagt caaaactgaa
     2521 acaattccac tgtctaactt catatcagaa atcgcttgtt ggctgttatg tgcagagact
     2581 agaatctttt taacattttt tagagttgtt acaatttttt tgcgcctatc tgcttgatag
     2641 gttaaaaaac catctgggca gagggctatc agattcagtg cttcagcgtc cttatctttt
     2701 tcaatggctg aaacctcgta attttctgct gctaagttgc cactggttag aatgagtggt
     2761 ctatcacagc ctgggcatgc acaacagtta ttagattctg ttaacaagaa ctgcccgtat
     2821 tgttttttga gttgattcga ctgggtagtg aacgctgtat tttgcacagt ggttaatttt
     2881 acaatccctg tcttctctct gatggttacc agaagatacc ttggaattgc ggtgtcgact
     2941 tgaccatggt gccttttggg cagggttata aggatatgag tccaccgtcc aaggaactct
     3001 ataaactcat gatggtaggg aaaatctaac atgttggtca tccagtcctt aaatggatgg
     3061 gacaaaacgt ggtgatgcga caagcccctg gaggcaacat caagccagat aaggaaaaat
     3121 ctgttgagaa gattgacggt attgtaggtc ttatcctggg gcttgaccgt tgcatttgcc
     3181 gccaaggtga tgaagctagc gtctatgatg agcgagggat attgagtttt tagttgagtc
     3241 aactctaaaa acgtgataca atgtcgttac aaaaaaggag gataaccatg gctaaaacgg
     3301 gaactttgaa tttacgagtt gatgattcag taaaaagtgc ggcagatgat attttgaaac
     3361 gcttaggtat tcctatgtca actgcgattg atatgttttt gaatcagatt attttgactg
     3421 ggggtatccc atttgatgtt tctctacctg aagcgcctca acgagttaat gttgattaca
     3481 tgagtcagga gaagttttat gataagctta tcaccagctt tgaagatgcg aaaactggca
     3541 accgtcagga tgtcagagaa tttctatttc aattgaagga aaatgcttaa tgaaagaata
     3601 tcaggtcacc atgtcggatg atgctaaagc agatttgctg agcatctatc actatgttcg
     3661 tgatgaactc tgtgcaccac aggcagcgga tgatcttctt gagaggttat cccaaggaat
     3721 gttatcacta tccatttttc ctgaacgttg tgccatcatt gaggatctga ttggaaaagg
     3781 ctataccttc agacaactga ttgtcaaaaa atatcgcatt gtatatcatg ttctggaaga
     3841 tgaagttata attgttgcgg tcgtctatgg atcacgtcat atgaataatt ggtaaagtaa
     3901 gggagagtga tgtatggaac tcgtaaagac gatacaaatt ggtgatgaca tctatcctcc
     3961 gatacctgac ctatttggca ttcaagagaa tcaggagttt aacctttata aatcaactga
     4021 tggaactttg gtgttaagtc catctgatag caaactatca gcggatcacc aaagtataag
     4081 cagtgatgag cagatgacaa cagctgttga acaagcaagg ttagatgaga ttgcgacttc
     4141 agtattatca cgacatcttg acgcatttaa ggaattgaca gaatgagaat actaggtttt
     4201 gtaagaaaga ctgttgatta ctttgaaaga aatataccga aagcacttca aaggaggtgc
     4261 tttttttgta ccccaaaata aggagggctt atgggactac ttgatttaat tggaagaaaa
     4321 agggctagag ataagcccca aaacagttat gaaggtcagg acttttccta cctctttggt
     4381 cgcacgacta gtggcgagaa tgtggatgag tttaagacta tgcagacgac ggcagtctat
     4441 gcctgtgtgc gtgttcttgc tgaagcggtg gcgtcacttc ctattcacat ctatgaacgg
     4501 acagaaaatg ggaaggagaa aaagctggac cacccactgt actttcttct tcatgatgaa
     4561 cccaatccag agatgtcctc ctttatcttt cgagagacaa tcatgagcca tcttttgata
     4621 tggggaaatg cctatgtaca gattatacga gataaaagtg gtatggtatc gctactgcta
     4681 aagcagaagg cgagcgttct gataagaaag ctgctcttga ttatctggca acggatgcct
     4741 tagaagcacg aattgcagca cttcacaaag ctaagattga tgagttgacc gtctctagtt
     4801 cagcatggat gccaaggctt atctcccaac agattctatc agagtatgtg aagagcctag
     4861 aagttgaagc tgataaggtc gttattccag gacagaatac tccagtcttt agttgggata
     4921 gggatgggaa tgggaatctt tccattgaca caccgctcct aaaggtgaga ggggaaagtc
     4981 tagcgacaca agctgacctt acaaccatct ctttaactcc tggtccaaag ggagaactct
     5041 ggcagacaag tgttgaaagg ttggatataa aagtagacaa gcacatcagc ctaaccttca
     5101 aaaatggcgt acggattgat tgataaaagg caagggcgta ttaattcggc acgtcctttt
     5161 ttagtttatc tgtggtataa tgaaagaagt tatattggga gttgagatgc acgattcatt
     5221 tgaattttgc actccctaaa aagggtaaag gttagattgt atgataaaac taatagcaac
     5281 agaaatagga ataaagtgga taatacaata aaagttctaa atagcttgaa acaaagggac
     5341 taggagtttg agtgggaatt ttaatactct agggtaattt tatgtagagt gtttgaaaat
     5401 aataacgtta aaaagttagt aatcgttaaa gaatttaaaa taaattgtaa tagtttatcg
     5461 cttgttttat cgcttgaaga acgagcgata aatttatttt tatggtataa ataagaaaaa
     5521 agattgtaag gagaaaatga tgaaaccacc ttttacagtt acgaatacca tgttaaataa
     5581 ggtagtagag atttctaaaa ttattggtaa tttagaatta caagtacaga aagatttaaa
     5641 attaagaaaa gaaaatcgta ttcagtctat tcactcatca ctcgctattg aacaaaattc
     5701 tttaacagta gaacaaataa cagccattat tgatgggaaa agagtgttag ggaacccccg
     5761 tgagataaga gaagtaaaaa acgcttatga agcttatgaa gaaattttaa cgctaactcc
     5821 ctatgatgaa tcacattttt ttaaaatgaa gaaatttcaa cagtacattt accgataaca
     5881 acatcgtcaa tcacaagtcc tatggggttg gggagtgatt cgctacctgt aaaaatttcc
     5941 ttatttgatg ttgataccta tcttgcagat tcgatgcagt ttcacttaga gtatatactt
     6001 agactttttc caaagtcagg agttcattac ttaatgccta cttttagagg agaagcagta
     6061 gatcatcgac atttatcgca attttatcat agtgagtgtg agatagaggg agatttacac
     6121 tatgtgatga atttagtgga tagatatatt aagtttctgg ttagtgaaat tcttagagag
     6181 tgtcgagata gtatttttgc tataacaaaa gatgtaagtc atttggaaag ttttattgat
     6241 cgaaagatac caattattac gtttgaagag gcttgtacta tattggaaaa tgaaatagat
     6301 tcattggaat ataatgatga acatcatttt tatgtgttaa cagatgttgg ggaaaagaaa
     6361 ttaatggaac attttgaggg agtagtttgg gtaaaaaatt atccctgtaa aagtgtccct
     6421 ttttatcaaa ggttctcaac agatcatcta tttgcctata atgcagattt gttgttagga
     6481 ataggcgaaa ctgtaggttg tggagaaaga tgcgaaacat atgaagaagt tgtagaaaat
     6541 atgaattatt tacaagtaga tgcttctgaa tatagttggt atttagaaat gaaaaaaaca
     6601 agacctatga aatcttcagg atttggttta ggagtagagc gtttaatagc gtggatattg
     6661 aagtgcgatg atgttcgaaa agttcaatta atcagtagag aaaatgggat tgattattta
     6721 ccataaagga ggaagaaaaa tgaaaaagaa tattttaatt gtaggtggag gtccagagat
     6781 aactatatgt tatgatttaa ttaacaatag tacggagtat aatttctttt cagtatcaga
     6841 aattcctacg atgtatccag agttgtttgt agaaacaatt gaaaccagct ttagaaattt
     6901 tggaaagacg attgaacaaa ttaaagagct caaatattct attgatgctg ttgcttgttg
     6961 ggatgaagct ttaacgcata tagctgatga tatttcaaaa gaattaggat tgaaccctat
     7021 ttcatcgcta gattctcaat cattcaggtt taaagatcga atgagaatgg tatgtgaagc
     7081 tggtggacta aaaatgccca aatataaaat tatcaatcaa ttttcagata caaataaaat
     7141 aatcaattgg aaatatccat taatagtgaa accaacctct tttttagcaa gtataggagt
     7201 gaaaaaagtt tataattttt cagaattaca acaagcagtt tctcaaatgc ttaatgtaaa
     7261 atttccggtt tacatagctt caggggtata tgaattgggg gaattatata atttagaacc
     7321 tagagttttg gtggaagagt ttattgatgg agaagaatat agcttagaga gcgtggtaag
     7381 aaatggaatc tatacacctc tagggataac taaaaaaata gtagatgaaa aattatttat
     7441 ggatgaaata ggccatattt tcccttcaaa tttaaacaaa gaagaaaaaa gtagagtata
     7501 ttcttgggca gaaaaattac atcaaatttt gc
//
LOCUS       DAUNLR010000067         7528 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUNLR010000067 DAUNLR010000000
VERSION     DAUNLR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7528
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.067"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            15..866
                     /locus_tag="VLL59_001595"
     CDS             15..866
                     /locus_tag="VLL59_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HER6509707.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            863..1819
                     /locus_tag="VLL59_001596"
     CDS             863..1819
                     /locus_tag="VLL59_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HER6509708.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            1873..3228
                     /locus_tag="VLL59_001597"
     CDS             1873..3228
                     /locus_tag="VLL59_001597"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HER6509709.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            3352..3993
                     /locus_tag="VLL59_001598"
     CDS             3352..3993
                     /locus_tag="VLL59_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509710.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            4056..5186
                     /locus_tag="VLL59_001599"
     CDS             4056..5186
                     /locus_tag="VLL59_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HER6509711.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKAAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            5196..5948
                     /locus_tag="VLL59_001600"
     CDS             5196..5948
                     /locus_tag="VLL59_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HER6509712.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            5948..6712
                     /locus_tag="VLL59_001601"
     CDS             5948..6712
                     /locus_tag="VLL59_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HER6509713.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHVETSIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            6712..7344
                     /locus_tag="VLL59_001602"
     CDS             6712..7344
                     /locus_tag="VLL59_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HER6509714.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDSLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
BASE COUNT         2302 a         1321 c         1608 g         2297 t
ORIGIN      
        1 gaaatgagag ttgtatgaat aatttatcta gtatcgatat taaattttta ttaagcttat
       61 ttgcggatcc ttggctgctg gcagtgcatc ttttagatat tctaattgtt gcctatttga
      121 tttatcgttt tattaaagca ttgactggaa ctaaaatcat gtctttagtt caaggggtca
      181 ttttcttttt ggttcttcgt tttattgcag agtggattgg ctttacgaca atcacatact
      241 taatgaacca agtcattact tatggtgtaa ttgcaggagt agtcattttt acccctgaaa
      301 ttcgggcagg actggagaaa tttggtcgtt ctacgcaagt ttttttacaa aaacagtacg
      361 tcagcagtga atctgctttg gtcgatgctt tgattaaatc tgtggcctat atgggtccac
      421 gcaagatagg tgcactgatt gctattgaac agactcaaac cttacaagaa tatattgcga
      481 caggaattcc gctgaatgcc gatatttcaa gtcaactact catcaatatt tttattccga
      541 atacgccgct tcatgatgga gctgttatcg ttggtcagaa taagattgtg gcagcctgtg
      601 cctacttgcc tttgtcagaa tcaaaggcaa tttccaaaga atttgggacc cgtcatagag
      661 cggctattgg attatctgaa aactctgatg cactaactat cattgtttca gaagaaacag
      721 gagctatttc agtaactcgc aaaggccaat ttttacatga tttaagcaca gatgaatttg
      781 aaacggtact taggacctac ctgatgagtg attcaaatgt tagtttacca tggtataaga
      841 aaattctagg agggaaatct aaatgaaacg atttttaaat agtcgtcctt ggttaggaat
      901 ggtatcagtc ttttttgcga ttctcctttt tttaactgca gcatcgagca atcataataa
      961 ctctagctcg caaatttata gtccgattga aacctatacg catagcctta aagatgtacc
     1021 aattgatatg aagtatgata gtgacaaata ttttatcagt gggtattctt atggtgcgga
     1081 agtttatcta acctccacta atcgtatcaa attagattct gaagtgaaca atgatacacg
     1141 taattttaag attgtggcgg atctaacaca tagtcatcca ggtacagtaa gtgtcaacct
     1201 aagagtagaa aaccttcctt ctggggtgac agctaccgta tctccagata aaatatcagt
     1261 cacaattggc aaaaaagaat ctaaggtatt tcctgttaga ggaagcgttg atgctaaaca
     1321 aattgcaaat ggttatgaaa ttagcaaaat tgaaacgggg gttaataagg ttgaagtgac
     1381 cagtgatgaa tctaccattg ctttaattga tcacgttgtg gcaaagttac ctgatgatca
     1441 agtgttagat aggaattata gtagtcgagt gaccttacaa gctgtctcag ctgatggaac
     1501 tattttagca agtgcaattg atcctgcaaa aacaaattta tcagttgctg taaaaaaaat
     1561 aacgaaatca gtcccgatta gagttgaggc agtggggatg atggatgata gcttatcaga
     1621 tattcaatac aaattgtcaa aacaaacagc tgttatctca ggtagtcgag aggtcttaga
     1681 agatattgat gaaattattg cagaagttaa catttctgat gtcactaaaa atactagtaa
     1741 gaccgtgagt ttgtcttcta gtcaggtgtc aattgagccg tcagtagtga ccgttcagtt
     1801 gacaaccacc aaaaaataat ggataataac taggaaaatt gaatggagga agccattagg
     1861 cttatataaa ttatgggaaa atattttgga acagatggtg ttcgtggcga agcaaatgtt
     1921 gagctgacac ctgagttagc ttttaaactg ggccgattcg gtggttatgt tttaagtcaa
     1981 catgagaccg aaagacctaa agtttttgtg gcgcgtgaca cccgtatttc aggagaaatg
     2041 ttggagtcag ccttgattgc tggtctacta tctgttggta ttgaagttta taaacttggc
     2101 gttttagcga cacctggtgt ctcttattta gttagaacag aaaaagcaag tgcaggtgtg
     2161 atgatttctg caagtcataa ccctgcgctt gacaatggca tcaaattctt tgggaatgat
     2221 gggtttaagt tagctgatga ccaagaattg gaaattgaag ctctcttaga tgctccggag
     2281 gacacgcttc ctcgcccgag tgcagaagga cttggaacct tggtagatta tccagaagga
     2341 cttcgtaaat atgaaaagtt cttggtaaca acaggtactg acttaagcgg tatgacagtt
     2401 gccttagaca ctgctaatgg agctgcttca gtgtcagcac gtgatgtctt tttagattta
     2461 aatgcagaaa ttgctgtcat tggcgaaaaa ccaaatggtc ttaatattaa tgacggtgtt
     2521 ggttcaacgc atccagaaca acttcaagag ttagttaagg aaacaggagc agatcttggt
     2581 ttagcctttg atggcgatag cgaccgtctg attgccgtgg acgaaactgg tgagattgtt
     2641 gacggtgatc gtattatgtt tatcattggt aaatacttgt cagaaaaagg gcttcttgct
     2701 cacaatacca ttgtcacaac ggtgatgtct aacctcggtt ttcataaagc tttagataaa
     2761 caaggtatta ataaagcaat tacagcagtt ggagaccgct atgtggttga agaaatgcgt
     2821 agctcaggat acaatctcgg tggtgaacaa tcaggccatg tcattatcat ggactacaat
     2881 accactggag atggtcagtt gacagctatc caattagcca aggtgatgaa ggaaactggg
     2941 aaatcacttt cggaattagc tgctgaagta accatttacc ctcaaaaact ggtgaatatt
     3001 cgtgtggaaa acagcatgaa agaccgtgct atggaagttc cagctattgc gaacatcatt
     3061 gcaaaaatgg aggatgaaat ggctggtaat ggtcgtattc tcgtgagacc aagtggtaca
     3121 gaacctcttc ttcgtgtcat ggcagaggcg ccaacagatg ccgaagttga ttattatgtc
     3181 gatactattg ctgatgtcgt ccgtacagaa atcggatgcg ataactaacg agttgagtac
     3241 aaacaagaaa ccttatttct aaggcttctg tcaacaattg gaaagaggct tggggcgttt
     3301 agcccaagtc tctttttata aattgctaaa gtagaagaga aaggatatcg gatgacaaaa
     3361 cagcaaatcg aaaaactagc ggacttactg cctccttttg cagccacact ttacttagat
     3421 atgattcctg aatttcagga aggttatgct tcatatgttt atcaaacacc aaaacaagat
     3481 attcaaaagc gccgcatcaa gcagttaact aaaaattttg aacgattact agatacccca
     3541 tctttttatg tgatgcctgt gacaagaaaa acagcagagc aattgctagc agataaaggc
     3601 ctagcttatc atttgttatc gacagttgca gctaatcaag tgtttgcggc tgctgttaac
     3661 gaggatcaga cgctttttca agtgcttcga aatggagcaa gagtagcttt tgtgattctt
     3721 caagaaaagg gggaatttct agaaatgact ttagggattc ttgaaacagt gacagaaaac
     3781 gaggttccag cagctattgt ggaggctgtc cagacatatc ttctggcaga tatgcaagag
     3841 aaactccctt ctttaagcat tatggtcagt caagaatcaa gcaagctttt ttaccaagaa
     3901 caaggatttg ttttgctagc taagggttgc aagccaggaa acgaaaatga ttctgacgtt
     3961 tgtcagctcg taaaatattt ttccaagcca tgaagaatca agggaaatgg tttattcata
     4021 gaaacatttt atcatcaaag tggtataata agaccatgtc aaaaaaacct acttcagcct
     4081 atgtgcacat tcctttttgc acacaaattt gttattattg cgatttttca aaagtcttta
     4141 tccaaaatca acctgttgat gcttatttga aagccttgat tcaagaattt gactcttatg
     4201 gcattcgaga cctaaaaacc ctttatattg gaggaggtac gcctacagct atcactgcta
     4261 aacagttgga gtatctccta aatcaccttg aacgaaacct caatttagat gatcttgaag
     4321 aattcacaat tgaggcaaat cctggtgatt tgacgccaga aaaaattgcg gtgcttcaga
     4381 ggtcagctgt caatcggatt tccttggggg tgcaaacctt taataataag caattaaagc
     4441 agatcggccg tagccataat gaagaacaaa tttatagcac catcgctaat ttaaaagctg
     4501 caggctttca caatatttcc attgatttaa tttatgcctt gccaggtcaa accttagatc
     4561 aagtcaagga aaatgttgct aaagctttgg cacttgatat tccccacctt agtctttata
     4621 gccttatttt ggaacatcac accgttttta tgaacaaaat gcgacgtggt aaacttaact
     4681 taccaacgga agacttggaa gcagaaatgt ttgagtatat tatttcagaa atggaagcta
     4741 atggttttga gcattatgaa atttccaatt ttaccaaacc tggttttgaa agtcgtcata
     4801 acttgatgta ttgggataat gtggagtatt ttggatgtgg tgcaggggct tcaggttacc
     4861 ttaatggcat tcgttatcaa aatcgggtgc ccatccagca ttatcttaaa gcggttgaag
     4921 caggaaacgc tagactaaat gaagaagtgc tgcgcaaaga ggaaatgatg gaagaggaac
     4981 tctttttggg cttacgtaaa aagacaggag tctccatcca gcggttccaa gaaaaatttg
     5041 gtatgtcttt tgaggagcgt tatggaaata ttgttaggga gcttcaaaac caaggactgc
     5101 ttgtcaaaga tgacgccttt gtcagaatga ctaaaaaggg tcttttctta ggtgattctg
     5161 ttgctgagcg gtttatatta gattaggaga gtattatggg attaagttat caggaggagt
     5221 tgacacttcc ttttgaatta tgtgatgtca aatcagatat aaaattgccc cttttattag
     5281 actattgttt gatggtttct ggtagacagt ctgcgcaatt aggacgaagt aacaacaatc
     5341 ttttagttga ttacaagctt gtttggattg taacggatta tgagatcact attcatcgct
     5401 tgccacattt tcaagaaacc atcaccattg aaacaaaagc cctttcctat aataaatttt
     5461 tttgttatcg ccaattttat atttatgatc aagagggggg tcttttagtg gatatcttag
     5521 cctattttgc tttgttaaac ccagatacgc gaaaagtggc aactattcca gaagatttag
     5581 tagcgccatt tgagactgat tttgttaaaa agctacaccg tgttcctaaa atgcctcttt
     5641 tagaacaatc aattgatcgt gattattatg tgcgttattt tgatattgat atgaatggtc
     5701 atgtcaacaa cagtaaatat ttagattgga tgtatgatgt gttggggtgt gagtttttaa
     5761 aaacgcatca gcctcttaag atgactttga aatatgttaa agaagtctca ccaggcggtc
     5821 aaattacttc cagttaccat ttggaccaat taacttctta ccatcaaatc acctcagatg
     5881 ggcagctgaa tgcccaagcc atgattgaat ggcgagcgat taaacaaaca gaaagcgaga
     5941 cagactagtg ccttataagg gttatttaat tgatttagac ggaacgattt accaagggaa
     6001 aaaccgtatt ccagcagggg agcggtttat caaacgccta caagaaagag gcattcccta
     6061 tttattagtg actaataata ccacaagaac acccgaaatg gtgcaaagca tgctggctaa
     6121 tcagtttcat gttgagacaa gcattgagac catttatacg gctaccatgg caaccgtcga
     6181 ttacatgaat gacatgaacc gtggcaagac agcttacgtt attggagaaa cagggctcaa
     6241 atcagctatt gcagcagcag gttacgtaga agaacttgag aatcccgctt acgtggtggt
     6301 tggtttagac agtcaggtga cctatgagat gttggctata gccaccttgg ctattcaaaa
     6361 aggtgccctc tttattggga caaatcctga tttaaacatc ccgactgaac gtggtttgat
     6421 gccaggagca ggtgcattga atgccttact agaagctgcc acacgtgtaa aacctgtttt
     6481 tattggcaag cccaacgcta tcattatgaa taaatcacta gaggtattgg gcattcagcg
     6541 ctctgaagcc gttatggttg gcgataatta cttgactgat atcatggcag gtattcaaaa
     6601 tgatatagca acgatcctcg tgacaacagg ctttaccaga cctgaagagg taccaacctt
     6661 accaattcag ccagatcatg tcctatctag ccttgatgag tggaggttgt gatggtagaa
     6721 aacactaaat tactatgtag ctgggtatgg ttattagcgt tagctattct cataacgatc
     6781 tattcaacgt ggctgtggta tcctcttgag gtggaccatc taaagttaga acaagttgtt
     6841 tttatgagca aggatgctat cttgcataac tataacggac tactcaatta cctcaccaat
     6901 ccttttgtga caaggttgga atttgctaat tttcactcat cagcagacgg actcaagcat
     6961 tttgcagatg tgaagtggct ttttcaccta actcaagtcg tttttcttgg ccttctttac
     7021 ccaaccctta agactttcac acaaaggtta aaaaccaaac gtttctggct ccttcaaaaa
     7081 cctttaatac tagcagcttt gtttcctctt atgattggtc taatggctag tttcattggg
     7141 tttgaacatt tttttactct ttttcatcag gtgctttttg taggagatag cagctggctc
     7201 tttgattcct tgaaagatcc tgtgatttgg atccttccag aagtcttttt cttgcactgt
     7261 ttccttttct ttatgatagt ttacgaaatc atcctgtgga gcttagtagg tttagcaaga
     7321 tggcagcgcc taaatgtaga atgataaaag gattaagaga ttaatttccc taaaaatgat
     7381 aaaacaagcg ttttgaaagc gcttgttttt tagtttgtag tgagattaga atagaagtat
     7441 caaaaaaagc accgactcgg tgccactttt tcaagttgat aacggactag ccttatttta
     7501 acttgctatg ctgttttgaa tggttcca
//
LOCUS       DAUNLR010000068         7296 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUNLR010000068 DAUNLR010000000
VERSION     DAUNLR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7296
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.068"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            579..668
                     /locus_tag="VLL59_001603"
     CDS             579..668
                     /locus_tag="VLL59_001603"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HER6509715.1"
                     /translation="MIIDYCNNKRIKIKRKGLSPLQYKTKSFT"
     gene            complement(706..1629)
                     /locus_tag="VLL59_001604"
     CDS             complement(706..1629)
                     /locus_tag="VLL59_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509716.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1622..2692)
                     /locus_tag="VLL59_001605"
     CDS             complement(1622..2692)
                     /locus_tag="VLL59_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509717.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2701..3627)
                     /locus_tag="VLL59_001606"
     CDS             complement(2701..3627)
                     /locus_tag="VLL59_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509718.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3627..5129)
                     /locus_tag="VLL59_001607"
     CDS             complement(3627..5129)
                     /locus_tag="VLL59_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509719.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5194..7164)
                     /locus_tag="VLL59_001608"
     CDS             complement(5194..7164)
                     /locus_tag="VLL59_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HER6509720.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAGITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYEKAKEKWMKAKAKSNAKYAEKLADHVEK"
BASE COUNT         2280 a         1414 c         1346 g         2256 t
ORIGIN      
        1 actttttttg tactttttta tttgcccgcg ttgtaaaatg aagtgcaaca aaaaagagga
       61 aaagccttga actacacccc aaacgttaga caaaaaaatc taacgttcgg ggtatttttt
      121 atgaaattaa gtgatgaagg tacgaaatag acatcgttaa aaaaaatacc tactatccac
      181 cagagataaa gcaggaaata atggataacg ttttgataga aggcccgcca caataccaag
      241 tatcacttgt ttatggcttg ttacatgcag gaactctccc aagttgaata gcacaatata
      301 agaaaaacag ttatactgtt gagaaaacaa gagcaagacc atcacaaaca ggacgtaaac
      361 caaaagaaac ctgaagaaat gactaaatta gagcggcttc aagaagaaaa tgaatatctc
      421 agaactgagg ttgcttactt aaaaaaaccg agggaactcc gtttgaaaga agcatctctg
      481 caaaaaagaa gacaaaaaac cattataaag aatggacaaa gacgagctct gattagattt
      541 tcttttaaga acggctaaat tgactcgttc tacctactat tatcatcgat tattgcaaca
      601 ataaacgtat caaaataaaa cgaaaaggac ttagtcctct acaatacaaa actaaatcct
      661 ttacttaaaa tagagtgttc aacttttggg gtcagtgcat ctcttttaca attctttttg
      721 atatttttca atttctgctt ggtttgccca aacaaagtga tttggtttga tttcaaccat
      781 tgatggctta tctaatgtat aatcatgctg gtctggatga tagacaacaa gttctttttg
      841 acgctctaaa attggatctg ggataggcac ggctgataac aaagattggg tgtagggatg
      901 aattgggtta ttaaacagtt cttctgtttc tgcaacttct acaataaccc ctttatggat
      961 aaccgcaata cgatctgaaa taaagcgaac gactgaaaga tcatgggcaa tgaagagata
     1021 agtcaaacct ttttcggctt gcatccgttt gagaaggttt aaaacctgtg cgcgaacgga
     1081 aacgtccaaa gctgaaatcg gttcatcagc aataacgaat tcagggttca ttactagggc
     1141 tctagcgata ccgatccgct gacgttgacc tcctgaaaat tcatgagggt agcgcgtcaa
     1201 atgctctgat agcaaaccaa cttcggccat catgttctta attttttctt tacgttcttc
     1261 ctctgtttta aacagattaa agttataaag accttctgaa atgatgtagt caacggttgc
     1321 ccgttcattc aaactagcag cgggatcttg gaaaatcatt tgaattttac gaatgagctc
     1381 attggcttct gattttgatt ttctgccatt aattactttc ccatcgtata aaatttgacc
     1441 tgaactagta tcgttcaaac caataatagc acgaccaatt gttgttttac cactcccaga
     1501 ttctccaact aaagaaaagg tttctccttt tttaataaag aaattagcat ttttaactgc
     1561 aacaaatttt ttctttcctt ctccgaagga aatttctagg tcttttactt cgactaattt
     1621 ctcagacatt tccttcctcc tgttgtgaca ttttccttaa gattttttga tgcaaatctt
     1681 gaatgacttc tggtttttga acttttggag cctctgggtg taaaagccat gttttggccc
     1741 aatgagtctc agatacgtta atcgccggag gtgctttttc aaagtctaaa accatagcat
     1801 attctgagcg aagtgcaaag gcatctccga taattggtga ataaagtgat ggaggcgttc
     1861 ctggaatagc gtaaagttca ccagattcat ctgccaactg cggtaagcta gacagcaaac
     1921 tccatgtata ggggtgtctt ggatcataga aaatctcttc gactgttcca aattcaacaa
     1981 tttctcctgc atacatgaca gccactttat ctgcaatgct tgccacaaca cctaaatcgt
     2041 gcgtaataaa gataatggtg aaatgatatt ctcgttgaag cgacttcaat aactcaacga
     2101 tttgagcttg aatagtcaca tcaagggctg ttgttggctc atcacagata agaatatctg
     2161 gacgacaagc taaagcaata gcgataacaa tacgttgacg cattcctcct gaatactcaa
     2221 atgggtaatc ttcaaagcgt tttttggcat ttgggatacc cactttattc atgtaatcaa
     2281 gggccatttc tttagctttg gcatgactta ctttttggtg cttaataatc acttctgtga
     2341 tttggctacc gatagtttta atgggactaa gactggtcat tgggtcttgg aaaatcgttg
     2401 cgatttttga gccgcgaatc tttgcccact ctttatttgt ttttaaatct gtcaattctt
     2461 gcccacgata gacaattgaa ccattagcaa tgcgtccatt agactccaac atccctgtaa
     2521 aggtctttgt taaaacagat ttacctgagc ctgattcccc tacaaaagca aggacttctc
     2581 cttcaacaag ttccagtgag acgttacgga tagctgttaa aacacgatca cgcacatcaa
     2641 attctaccac cacatctttg gcagttaaga ttacattatt ttcttttgtc attttaactc
     2701 ctatctatgt gaacgtgggt cactggcatc agccaagttt tgtccgacaa tgtatagtgg
     2761 taacgatact aaaatcaatg ttactaaggg aatccaaaag aggtaggcat ttgttgttaa
     2821 gttgcttgaa taattagcaa tcaaacgtcc taaacttgga gtggtggttg gtaaaccaat
     2881 cccaaagaag gataagaagg cctcagaaga tacataaact ggtagcattt gtgacaacat
     2941 agtcatgata actgaaacca attgaggcag gaggttctta acagcaatct tgtacattgg
     3001 tgttcccaaa gtttgactag caaggttgta ttctaaatca cggtaacgca agatttgaac
     3061 acggatggag taggcgacac caatccatcc agtgatacag aaagctagaa tcaaattcca
     3121 aaatcctgca cctaatgaat aggtcaaaac aatgataata agcatagaag ggatatttga
     3181 gataatgtta taaatttcaa tcataacttt atcaaatgct ttagaaactc cccatatggc
     3241 tcctaacact accccaatgg tgatattaat tagtgtcgct ataactgaga ttaaaataga
     3301 attacgtgcc ccataccaaa caccatcaaa cagagattgc ccatttttgt cggttccaaa
     3361 ccaatactct gcatttggcc aaatataacg ctttgaaaag tcattgatat tactaacgtc
     3421 attaaagtcg tagttggcaa acattggata aataaagctc atcatcaaga ctgtcactaa
     3481 aatcacgagc ataaagactg tagatttttt agaaaaaaac tgacgaaaca ctgatttcca
     3541 gtaagaataa gcaggggtat caatcacttc ggaggcttca ctatcgcgct caacaaatcg
     3601 aaatttagat ttatcaatcg attccattac ttacctcctt tttttgttga caatttaata
     3661 cgtggatcga caagggtcat gacaatatct cctagtaaaa gtgaaacaat tgacaagaca
     3721 gtgaagataa aggttaatcc aacaatcata gaattgttag cagatttaat agaatcaatt
     3781 aacattttac ccatacccgg gaaggcaaag acagtctctg ttaaggttgc accaccaata
     3841 gcaaggataa tacttgcagg aacccctgac acaattggga ccatggcatt tttgaagaga
     3901 tgccctctgt aaatttcaga ttctgataat ccttttgaac gcgcaaaacg tacccaatca
     3961 ctggcctgaa ggtcaacaag atagcgacgg aaccagataa ccgtagttgg aatatttaaa
     4021 attcctaaaa taagggctgg taaaatataa gatttaggat cagatgcccc cagcattggg
     4081 aaactatctg gtaaaccaac catgccacct aggaagcgaa caacatagat aacagcaata
     4141 cttggtaaag caagcatgaa ggtcatggtc gctgttgaga aacggtcaaa ataggtattt
     4201 ttaaaccgag ccataaataa accaagaggc aaaccaacga tataggaaaa cataacacca
     4261 aaaaaaccaa ttacaaaaga attgtgaatc attgatgggt cgacataatt attgatggtt
     4321 ttagtgtagg aatctccctt accatagttt accttggtga tatcatccaa tgattttgga
     4381 tttttgtagc tacggctata gatatccact gacgatttct tagtgacacc tgatgggaag
     4441 gtcacatctt gaagagctgt tcgtccttgc ccttgtgaaa taacctgaag aacaggaata
     4501 ttgctgtatg ttggataaga tgttcctaag tttagggtaa caaagttttg gtgaagataa
     4561 ggaaattttc cgttagtata gaggagatat ttatgttttg tccccgaacc aacaagtgac
     4621 cagccaactg atttatcttt ttctagacga atatacctag ctaattttgg attatcttta
     4681 tcctgaatct tccaagggtg atcaataaca actagatttg agaaaaagtt ccaaacacgt
     4741 tcgtaaatag gaatattgcg aattgcataa aactgtttgc tagtggggaa gcgttttagc
     4801 tgccagccat tgccaagaga atcaatatac ttctcataga tagctttgtt agcactagtt
     4861 gcttctgtcg ttacactact atctacttta gaagcattat cttttaattc tttgcttgaa
     4921 aaataattga cataacccat acgttgaaaa gttagatttt catacgctac ttttttatct
     4981 ggtgttgttg tcattttatt ataattaggg tcttgtttaa agataaggct ggtaggtact
     5041 aaagtatata cgatggtgta tgttaaagcc gttaccaaaa ctaccgacac taacgatcgc
     5101 atgatacggt ttaaaatgta ttttttcata gttgtcctca atagttcaaa agaactccct
     5161 cacataaacg agaaagttct tttgaacatc gttttatttt tcaacgtgat cagctaactt
     5221 ctcagcatat tttgcatttg acttagcctt tgctttcatc catttttctt ttgctttttc
     5281 gtattgtttt gctgtgacag gtttgtcttg aagtttcatt cctttatatg ctagaggacc
     5341 tttagaccct gcccaagaga agcccccgct aaatggaacg gctttagtaa ctcgtggagt
     5401 gccacccaat gccacaactg gaatatctac ggcattatct gtaaggtagg cttgtgcttt
     5461 tgcgtaagct ttatagcgcg catcgttgtc gtctgtaatt cctgctgctt catcaagaag
     5521 agtttggtag gtatcaaggc ctgcagctgc cacaacatcc ttattttgac ctgctttgat
     5581 tccaagtttt tggataacag atccaccacc tactggactc atgatgtcaa ggtaggtccg
     5641 tggatcttgg tagtctggtc cccaccatga tgaaatgata tcgtagtctt gttgttctgg
     5701 ggtctcagca tagaagcctt gggcttcgtg agttgatgtt tctgtttcaa gaacattgac
     5761 aatgacattt tctttaccaa gagatgcttc aacagattgt ttgaaagact gggcttcctg
     5821 aacagttgct gcgtttgctt ggtcaacagg gtaatctaat tgaactggga aggttacacc
     5881 ttcagctgtc aaagcttctt tggcttttgc aaactcagct tttgcttttt caggattata
     5941 gaaaccatct tgagcatcag ctaagttaac gtctttccat tcatcaccaa gttttgccat
     6001 ttccttttca acttctgaac caaaatcact ttctccaatg gtcacaaatg ttggtggcac
     6061 aagcatgtta cgtaaggctt ttgttttggc atcttgacct gcagtttgtg cttggaatga
     6121 cgctcggtca aaagcaaact gaatagcttg acgaaaatcc ttgttgttaa gagctttctt
     6181 accggcatct tgttgtgcag ggtctttctt agtgtttttg aaagaagtac ggttcaaatt
     6241 ccatgttaaa tgacggatat ctccagtcaa cattccgtaa gtaatgttat cagcatagtt
     6301 tttcttagct gatttgtagg tagggtcatt tgggtaaagt cgtgcaacgc tgaactcacc
     6361 cttgtcaaag ttcttgtaga acgaacctgg gtctgaacca tctgagtaag tcaatttaac
     6421 agattctatc ccaacattct tagcatccca gtagttttca tttttatgga attccataga
     6481 tgattttgag gtgaaggcac tcaagaagta agcaccatta acaaggattg atgatggatc
     6541 ggttgtacca aaatctttac cttttgactt caaaaatttc gcattaactg ggaaaagcac
     6601 actataagtt gtttttgaat tccagtagct ttcaggcttg ttcaaagtat actgaacagt
     6661 tttatcgtca agggctttga caccaacttc tttaaaatct acttcaccat tttggtaagc
     6721 ctttaagttt tttattgaat cttcaacaac gtaaagagca tctgatttat cgtcaaccgc
     6781 gtgcttcaaa ccagtcacaa aatcttctgc tgttactggg gcatattctt caccatcagc
     6841 cgtataccaa gagacaccat cgcgaagagt ataagtataa gtcagaccgt cttttgaaac
     6901 cttccaatct ttagcaagtg atggtactaa attaccatac tcatcgtttt ccaaaagacc
     6961 atcaaccatt tgtgttatca catcagtcgt cccaccgcca ttagtcaaaa tataatccaa
     7021 tgattttgga tcgttaacaa aaacgtactt gtaggttttt gtagcttctg agccacctga
     7081 agcattttta ttaccacaag ctgccaaagc ggatactgac aagatcgcaa cacttacagc
     7141 tgccaaccat ttacttttct tcataaaagt cacccctaaa ctttattttt cattttttgg
     7201 caattgctaa atgaaattgg ttaattgaag acattatatc ataaaacttt cttaaagaaa
     7261 ataatgaaat gaaaaattat ctgaatattt cgtaga
//
LOCUS       DAUNLR010000069         7281 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUNLR010000069 DAUNLR010000000
VERSION     DAUNLR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7281
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.069"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            375..803
                     /gene="lacA"
                     /locus_tag="VLL59_001609"
     CDS             375..803
                     /gene="lacA"
                     /locus_tag="VLL59_001609"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HER6509721.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKHEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNSRII
                     TLGSEISAPGIAKNIVKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            838..1353
                     /gene="lacB"
                     /locus_tag="VLL59_001610"
     CDS             838..1353
                     /gene="lacB"
                     /locus_tag="VLL59_001610"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HER6509722.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            1399..2328
                     /locus_tag="VLL59_001611"
     CDS             1399..2328
                     /locus_tag="VLL59_001611"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HER6509723.1"
                     /translation="MILTVTLNPAIDVSYPLNELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIGIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTRDFDALKEVLQDKLFDGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKIKEV"
     gene            2332..3315
                     /gene="lacD"
                     /locus_tag="VLL59_001612"
     CDS             2332..3315
                     /gene="lacD"
                     /locus_tag="VLL59_001612"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HER6509724.1"
                     /translation="MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKISDNASPEFAKVKAHKVNEAMKVFSEERFGVDVLKVEVPVNMKFVES
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            3339..3656
                     /locus_tag="VLL59_001613"
     CDS             3339..3656
                     /locus_tag="VLL59_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HER6509725.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            3656..5353
                     /locus_tag="VLL59_001614"
     CDS             3656..5353
                     /locus_tag="VLL59_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HER6509726.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKTCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHSTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILTEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKAQFEN"
     gene            5441..6847
                     /gene="lacG"
                     /locus_tag="VLL59_001615"
     CDS             5441..6847
                     /gene="lacG"
                     /locus_tag="VLL59_001615"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HER6509727.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPADVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
BASE COUNT         2405 a         1165 c         1468 g         2243 t
ORIGIN      
        1 aaacaaaaca aatataaaca ttggaaaaaa caaaaattaa caaaatagaa aatgttttaa
       61 ataaaacgtt tacaataaat agagataagg gtttcgtaat atatgatagg ttacgagtgg
      121 ctgtcaaagg gatttatgaa atgaaaaaga aacacaagaa acattaggat aataacgtaa
      181 aaatgaaaaa aataaacatt ttttgtttat tttttataaa aataaacaaa aaatgttgac
      241 ttttatgttt ggtgggtgta tgattaggtc atagaaataa tgaaagcgtt atttcaaaag
      301 atgttgcaaa tcgttaatta actatctacg taggttttcc acattcactt attctaaatc
      361 ataggagaaa taaaatggca attattatcg gtgctgacaa agcaggtcaa gaacttaaag
      421 aagttatcaa agattacctt aaagaaggta aacacgaagt cgttgatgtt agtgaaaacg
      481 aagtacgtga ctttgtagat acaactttag ccgttgcaaa agaagttaat gcatccgaag
      541 ataacttagg tattgtcatt gatgcatatg gtgttggttc tttcatggta gctactaaaa
      601 tcaaaggaat ggtggcagct gaagtatcag atgagcgctc agcatacatg acaagaggtc
      661 acaataactc tcgaatcatt acgcttggtt ctgaaatcag tgcaccagga attgcaaaaa
      721 acattgtcaa aggctttgtc gaaggtaaat atgatggtgg acgtcatcaa gttcgtgtcg
      781 acatgcttaa taaaatgtgc taattgattg aaataggtta aaacaaggag aacaaaaatg
      841 aaaattgctg taggttgtga ccatattgtt acttatgaaa aaatcgctgt tgtggattac
      901 ctaaaatcac aaggtcataa agttattgat tgtggtacgt atgataatgt tcgcacacac
      961 tatccaattt ttggtaaaaa agttggtgaa gcagtagcaa gtggtgaagc agaactaggt
     1021 gttgttatct gtggtactgg tgttggtatt acaaatgccg taaacaaagt tcctggaatt
     1081 cgttcagcac tcgttagaga tatgacatct gctatctact caaaagaaga gctaaacgca
     1141 aacgttattg gttttggtgg aaaaatcatc ggtggtttat tgatgaatga tattatcgat
     1201 gctttcttag ccgcggaata caaaccaact gaagaaaata aaaaatggat tgaaaaaatg
     1261 gatagcttgc aacatgctag ccaagatcaa aacaacccac acttctttga tgaatttcta
     1321 gaaaaatggg accgtggtga atatcacgac taatatttga aagaattatg ataaggatat
     1381 atagaaaaag gagctattgt gattttaaca gttactttaa atccagctat tgacgtctcc
     1441 taccctttga atgagctaaa atgcgatact gtcaatcgag ttgtagacgt tacaaagaca
     1501 cccggtggta aaggcttgaa tgtttcccga gttctaaatg actttggtga gacagtcaaa
     1561 gctactggtt gtattggtgg agaaagcggt gattttatca ttaatcatct tcctgattcg
     1621 attttaagtc gcttctataa aatttcaggt gataccagaa catgtatagc cattttacac
     1681 gaaggtaatc aaacggagat tttagaaaaa ggaccgatgt taagtgtaga tgaaattgat
     1741 ggatttactc atcattttaa gtatttactg aatgatgttg acgtagtgac gctctcaggc
     1801 agtctgcctg ctggtatgcc agatgattac tatcagaagt taatcggtat tgccaatctt
     1861 aatggtaaga agactgttct agattgttct ggaaatgctt tagaagcagt actaaaaggt
     1921 gatagtaaac caacagttat caagcctaat cttgaagaac tttctcaact tctaggtaaa
     1981 gaaatgacaa gagattttga tgccttaaaa gaagtcttac aagataagtt atttgatgga
     2041 attgaatgga taatcgtttc tctcggtgct gatggtgtat ttgcaaagca caaggatacg
     2101 ttttataacg ttgacattcc taaaattaaa attgtaagcg ctgtaggttc aggggattct
     2161 acagtggcag gtattgcttc aggtttagcg aatgatgaag atgatcgagc tttattaaca
     2221 aaagcaaatg tcttagggat gttaaatgcg caagaaaaaa caactgggca tgttaacatg
     2281 gcaaattacg ataagttata tcaatctatt aaaatcaaag aggtataaaa aatgacaatt
     2341 actttaactg aaaacaaacg taaaagcatg gaaaaactaa gtgtagatgg tgttatttct
     2401 gccttagctt ttgaccaacg tggagctctc aaacgtatga tggctcaaca tcaaacaaaa
     2461 gagccaacag tagaacaaat tgaagagctt aaaagtttag tttctgaaga actaacacca
     2521 tttgcatcct caattctact tgatcctgaa tatggcttgc cagcaagtcg tgttcgttca
     2581 gaagaagcag gcttgttgtt agcatatgag aaaacaggat acgatgcaac aacaactagt
     2641 cgcttacctg attgcttaga tgtttggtct gcaaaacgta ttaaagaagc tggagcagaa
     2701 gcagttaagt tccttcttta ctatgatatt gatggagatc aagatgttaa cgagcagaaa
     2761 aaagcttaca ttgaacgtat tggttctgaa tgccgtgcag aagatattcc attctactta
     2821 gaaattctaa cttatgatga gaaaatctct gacaatgcta gccctgagtt tgcaaaagtt
     2881 aaagctcata aagttaatga agcaatgaaa gtcttctcag aagaacgctt tggtgttgac
     2941 gtgttgaaag ttgaagttcc agtaaacatg aaatttgtag aaagctttgc agatggtgag
     3001 gttctcttta caaaagaaga agcagctcaa gctttccgtg accaagaagc ttctactgat
     3061 ttaccatata tttacttgag tgcaggtgtt tctgccaaat tgttccaaga tactttggtg
     3121 tttgcagcag aatcaggtgc taaattcaac ggtgtcttat gtggacgtgc tacctgggca
     3181 ggatctgtaa aagtctatat cgaagaagga ccacaagcag ctcgtgaatg gttgcgtaca
     3241 gaaggtttca aaaatattga cgaattaaac aaagtactag ataaaactgc aagtccttgg
     3301 actgaaaaaa tgtaacatta ttttcggagg aaactacaat gaatagagaa gaaactactc
     3361 ttttaggttt tgaaatcgta gcctatgctg gtgatgcccg ttcaaaattt ttggaagcgc
     3421 ttaaagcagc gcaagaagga gattatgcta aagcagaaga attaatcgct gcaggtagtg
     3481 actgcttgaa tgatgctcac aatgctcaga caagtctact acaaaaagaa gcagctggag
     3541 atgacttagc ttatagtgtc actttaatgc atggtcaaga tcatttaatg acgaccattt
     3601 tattacaaga tttaatgaaa cacatgattg aactttataa gagaggagca aaataatgaa
     3661 tggattaatt gctcagattg agaaagggaa acctttcttc gagaaaattt ctcgaaatat
     3721 ctatcttcgc gctattcgtg atggttttat cgctggtatg ccagttatct tgttttcaag
     3781 tatctttatc ttgattgcct atgttccaaa tgcatggggc ttccattgga gtaaggatat
     3841 tgagaatctc ttgatgacgc catacaacta ctcaatgggt attttaggtt tgtttgtggc
     3901 tggtacgaca gccaaagctt taactgactc aatgaatcga tcattaccaa gcacaaacca
     3961 aatcaacttt atttcaacca tgctcgctgc tattgtaggt tttctactaa tggcagcaaa
     4021 tccagcaaaa gacggtggtt tcttaactgg atttatggga acaaaaggtt tgttgacagc
     4081 cttcatcgca gcttttatta ccgtaaatgt ctataaaacc tgtgtgaaaa acaatgttac
     4141 aatccgtatg ccagaagagg tgccaccaaa tatctctcaa gtatttaagg atttgattcc
     4201 atttacgtta tcagttgtac tgctttatgt gattgaattg attgttcata gtactttagg
     4261 cgttaacgtt gcagaatcaa ttggtaaact tcttgcacca ttgttccaag cagcagatgg
     4321 ctatgttgga atcactatta tcttcggtgc atttgctttc ttctggtttg ttggtattca
     4381 tggaccatct attgttgaac cagccattgc agcgattact tacgcaaatg ctgaaaccaa
     4441 ccttcaatta cttcaagctg gtgaacatgc tgataagatc ttgacttcag ggactcaaat
     4501 gttcatcgtt accatgggtg gtacaggtgc aacacttgtc gttccattca tgttcatgtg
     4561 gttgacgaaa tcaaaacgta acaaagccat tggacgtgca tcagttgttc caacattctt
     4621 tggtgttaac gaacccattt tgtttggtgc tccacttgtt ttgaacccaa ttttctttat
     4681 tccatttatc ttggcaccga ttgtcaacgt atggattttc aaattcttca ttgacacact
     4741 tggaatgaac agtttcactg caaacttacc ttggacaaca ccagctccat tgggtcttat
     4801 ccttgggaca aacttccaag tgctagcatt cattttggca gctttgttaa ttgtcgttga
     4861 tgtgatcatc tactacccat tcttaaaagt atatgatgag caaattctta ctgaagaagc
     4921 agcaggtacg aattcatcag atgccctcaa agaaaaagta gcagcaaact ttgatactaa
     4981 aaaagctgat gctattcttg aaaaatcagc agctaaagaa accaaagaaa tcactgatca
     5041 aactaatgtt ctcgttcttt gtgccggtgg tggtacaagt ggactactag caaatgcttt
     5101 gaataaagca gctaaagaat atggtgcacc tgtcactgca gcagcaggaa gttatggtgc
     5161 tcaccgtgag attttaccac aatatcaact tgttatcctt gcacctcaag tagcttctaa
     5221 ctatgaagat atgaaagtgg aaactgataa acttgatatt aaattagcta aaacagaagg
     5281 ggctcaatac atcaaattga cccgtgatgg tcaaggagct cttgattttg taaaagcaca
     5341 gtttgaaaat taagaaaaca gtttaaatgt cgtaaagttc tcaaacacaa aaattgtttt
     5401 gggaacttta tttttgaaag atattcaagg agaaactgag atgacaaaaa cattacctaa
     5461 agattttatt tttggtggtg ccacagctgc ttaccaggct gaaggtgcta cccatacaga
     5521 tggcaaagga ccagtagctt gggataaata cttagaagac aactattggt acactgctga
     5581 accagcaagt gatttttata atcgttaccc tgtcgatttg aaacttagtg aagaatttgg
     5641 tgtcaacggc atccgtatct ctattgcctg gtctcgtatt tttccaacag gaaaaggaga
     5701 agttaaccct aaaggggtag aatattacca caatctcttt gcagagtgtc ataagcgtca
     5761 tgttgagcct tttgttacac ttcaccattt tgatacccca gaagctctcc actcggatgg
     5821 tgatttcctc aatcgtgaga acattgaaca ttttgtaaat tatgcagaat tctgttttaa
     5881 agaattctca gaagttaact attggacaac atttaacgaa attgggccta ttggtgatgg
     5941 acaatacttg gttggtaaat tccctccagg tatccaatat gatcttgcta aagttttcca
     6001 atcacaccat aacatgatgg tctctcatgc tcgtgcagtc aaactcttta aagatagtgg
     6061 ttattcaggt gaaattggtg ttgtccatgc tcttccaact aagtatccat ttgacgctaa
     6121 caatcctgct gatgttagag cagctgaact ggaagatatc atccataata aatttattct
     6181 tgatgcaact tatctaggta agtattcaga taaaacaatg gaaggtgtta accatatcct
     6241 tgaggtaaat ggtggtgaac ttgatcttcg tgaggaagat tttgctgcac tagacgctgc
     6301 aaaagatttg aatgacttcc ttggtattaa ctattatatg agtgattgga tgcaagcttt
     6361 tgatggtgag actgaaatca ttcataatgg taaaggggaa aaaggcagct ctaaatacca
     6421 aatcaagggt gtgggtcgaa gaaaagctcc cgttgatgtt ccaaaaacgg actgggattg
     6481 gattatcttc ccacaaggct tatatgatca aatcatgcgt gtcaaagccg attatcctaa
     6541 ctacaagaaa atttatatca ctgaaaatgg tcttggttac aaagatgagt ttgtagataa
     6601 tactgtttat gatgatggac gtatcgatta tgtgaaaaaa cacttagaag ttatttctga
     6661 tgctatttct gatggtgcaa atgttaaagg atactttatg tggtcactga tggatgtctt
     6721 ttcatggtca aatggctatg aaaaacgtta cggtctcttc tatgttgatt ttgaaactca
     6781 agaacgttat cctaagaaga gtgcctactg gtataaaaaa gtagcagaaa ctcaagtgat
     6841 tgaatgattt tgagatactt ttttaataca tttttacacg tcatgttcgt ttactgaatt
     6901 atagtcacaa aaagtagatg atgttgacat ttttcaagca tagtattatt tgctgttgat
     6961 ggtaatccat tagttgtaag atcgggttat aagtgttttt agttgatgaa aatgggtttt
     7021 gaaagtttta tttaacatcc tttttcagat atttgacttc tgtcattcaa actcctgacc
     7081 tgattaaata agtaaagtaa ccattttctg attagagatt gatgttataa caagaagcga
     7141 ttagattgta aaatagctgt aaagaacgag ttttgttttt tatatcagag ggctatttgt
     7201 tataaagtga cctcttatgt gacatctcaa aaatcttact aaaaaatatg aaaaaagtca
     7261 tttttgcact ttttactcat t
//
LOCUS       DAUNLR010000070         7059 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUNLR010000070 DAUNLR010000000
VERSION     DAUNLR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7059
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.070"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            153..884
                     /gene="aphA"
                     /locus_tag="VLL59_001616"
     CDS             153..884
                     /gene="aphA"
                     /locus_tag="VLL59_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HER6509728.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            1062..2594
                     /locus_tag="VLL59_001617"
     CDS             1062..2594
                     /locus_tag="VLL59_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HER6509729.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVIVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            2757..3371
                     /locus_tag="VLL59_001618"
     CDS             2757..3371
                     /locus_tag="VLL59_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HER6509730.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSSNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQAYI"
     gene            3530..4678
                     /locus_tag="VLL59_001619"
     CDS             3530..4678
                     /locus_tag="VLL59_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HER6509731.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGILVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            4727..5407
                     /gene="radC"
                     /locus_tag="VLL59_001620"
     CDS             4727..5407
                     /gene="radC"
                     /locus_tag="VLL59_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HER6509732.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(5409..6104)
                     /locus_tag="VLL59_001621"
     CDS             complement(5409..6104)
                     /locus_tag="VLL59_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HER6509733.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(6114..6758)
                     /locus_tag="VLL59_001622"
     CDS             complement(6114..6758)
                     /locus_tag="VLL59_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HER6509734.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT         2243 a         1093 c         1340 g         2383 t
ORIGIN      
        1 tattttttaa atcgattatg ataatttttt agatcatctt tgttgaataa cttcatcctt
       61 attcagaact taaagggcac tattataaga atttgaaacc gctttactta aaccgtgtat
      121 ttttgtacaa taatgattaa ggaggttttt agatgaaaaa agaatttacc agtatcctgt
      181 ttacagttag cttttgtgga atcatagcat tgcctgtcga agctagtggc cctaaagttc
      241 cttatacaca agaaggtata acggccattt caaatcaggc aacagtaaaa ttgatttcta
      301 ttgctgatat cgcgagcagt ttagaaggac aaaaacctat aacggttagt tttgatatcg
      361 atgatacttt gttatttact agccaatatt ttcagtacgg caaagaatat ataactccag
      421 gctcatttga ttttttgcat aagcaaaaat tttgggactt agtcgctaaa cggggagatc
      481 aggattctat tccaaaagag tatgcaaagc aactaatcgc aatgcatcaa aaacgaggag
      541 ataaaattgt ctttattact ggccgaactc gaggatcgat gtataaaaaa ggtgagattg
      601 ataaaacagc taagtcactg gctaaagatt ttaagttaga caagccaata gctatcaatt
      661 atacaggaga taaagctgtg aagccgtatc agtatgataa aacatattat ataaagaaaa
      721 acggctcaca aattcattac ggagatagtg atgaagatat aaatgctgcc aaagaggcag
      781 gtgcaagacc tattcgcatt ttaagagctc ctaattcaac caatcttcct ttgccaaaag
      841 ctggaggata cggagaagag gttttagaaa attcggctta ttagtcaaat atttgtgtaa
      901 gaaaggaagt aacagtaatt tctttcatca ccccactgag taaccaatag cccagtgggt
      961 tttttgggtt acagaaatca gttctaaaaa agaatcactg gtaacttaag gttgtctttg
     1021 atacaatggt aacagtgtat ttaaaagaaa gagaggacaa catggaaaac cataaaaatg
     1081 aattcacctt ttccaacaaa tcaattattg cctatgtttg gcgtggtgtt atagttggta
     1141 ttattgctgg tgttattgtt agtttattcc ggttgttaat tgaagtgaca gctgactggg
     1201 tgattgaatg gtaccgatac gctcatatca attcgctgtt gctacttcct atactaagtg
     1261 tcagtttatt agctgtcctt tttgtaggtt ttttagtaaa gtctgattct gatataaaag
     1321 gatcagggat cccccatgtc gaaggagaac taaagggact aatgtcccca gattggtgga
     1381 gtgtcctttg gaaaaaattt ttaggaggaa tcatggctat ttctatggga tttatgctcg
     1441 gtcgtgaggg tccttcgatt cagttaggtg ctatgtcagc caaaggatta gctaagtttt
     1501 taaaatcgag tcgtttggaa aagcgagtgc taattgccag cggagcagca gcagggctat
     1561 cagcagcttt taatgctcca atagcaggcc tcttgtttgt tgttgaagaa atttaccatc
     1621 atttttcgcg tttaatttgg attacagcgc tagtggctag cttagtggct aattttattt
     1681 ctctgaatat ttttggattg aaaccagtct tagcaatgtc agaggcgatg ccttttttag
     1741 gactcaatca atattggttg ttgcttttac ttggattatt tctaggctgc ttaggctatt
     1801 tatatgagat agttatcctt aattttaata aactttatgt tattttaggg agttggttac
     1861 atctgccagc ttatttttac ggtattatta tggtttttct aattttaccg attggctatt
     1921 atttaccaca gttacttgga ggaggacatg gtttaatact ttctttatcc aatcaacaat
     1981 tgcctttgat gactatcttc ttttatttta ttattcgatt tattgttagt atgtttagtt
     2041 atggaagtgg cttacctgga ggtatttttt tacccatttt aactttaggt gctttggcag
     2101 gcctattatt tgggcaaata gcttctcaat taggtttatt gaaccaatct tttctttctc
     2161 tttttttgat attagggatg gcagggtatt ttgcggcaat ttcaaaagca ccactgacag
     2221 gcatgatttt ggtaactgaa atggtaggtg atttgaaacc cttaatggct atagctgtag
     2281 ttacttttgt ctcctattta gtgatggatt tgttaaatgg acagccaatt tacgaagcta
     2341 tgctagataa gatggcaatg aagcatccaa ctaatcttgt tgaaccaaca ttaattgaat
     2401 tgactgttgg tgataagatt gcagggaaat atgttaaaga gttaaagctt ccagaaaatg
     2461 tcttaattac aacccaaatt caccatcaaa aatctcaagt tgtgtcaggt aacacgcgcc
     2521 ttttatcagg agcaactatc tttttggtcg ttaatgaagc tgatacaggt tttgtccgtg
     2581 aggtattgat gtaggtatta atttatcaca attcggaaag ttcgagcttg tcttttagac
     2641 taagtcttcg aacgttttac tgctagagtt tcatctgaac caaagtgaaa cgcttttgat
     2701 gaagtcaagt aggctttttg ttatactaac aataaagata agctaaggag gctgagatgt
     2761 tagaaattgt ttcagaagag ctacgtcact atcaagaaca aaaattgatt gagtaccgta
     2821 acaaaaatca gttagcccca aaaggaggca ttgtatttgc aggtgattct ctcattgaat
     2881 tttttccttt aaaaaaagct tttggttcat gtttgcctat tattaatcga ggtattgctg
     2941 ggatagatag tcagtggtta ttgcgccatt tttctgtcca aattactgat ttagagccta
     3001 aacatatttt tttattaatt ggttgtaatg atatcgggct tggatatgat aaatgtcata
     3061 ttgtcaagac tattgtagag cttattagcc agattcgtag tcattgtgtc tatagtcaga
     3121 tttatctctt atctttatta ccagtttcca gcaatccccg atatcagaag actgtcaaaa
     3181 taagaacaaa tgctatgatt gatgctatta ataaagattt agcaatgatt ccaactatag
     3241 aatttattaa tcttaatact tgtcttaaag acgaaaaagg tggtttatca gatgagaata
     3301 ctctagatgg tttacatctt aattttccag cttatgctaa actagctgaa attattcaag
     3361 cttatatcta gcaaataaat gtactaatag cgatgaggca agaagtcaga tagcagatgg
     3421 ttcatcaatc aattaagaaa aaagttatca agataccatt aaaaatagtt gctcaaagtt
     3481 cttttaaatc aaaagattat gatatcgcta tgttgagttt tagtgtataa tgataattaa
     3541 aggagttacc atgaaatttg aaaaaaaaca agtcttctat ttagtcctta cgtttatctt
     3601 atgctatggg atcctagcaa actggcgaaa tggaacggct atcgttacga ctatttacaa
     3661 aacaagcctt cctttttttt atggagcagc aggtgcctat attgttaata ttgtaatgag
     3721 cgcttacgaa aaggtatatg tttatatctt taaagactgg tcacatgtct taaaagtaaa
     3781 acggggtatt tgtttactgt tagcgtattt gacatttttt attttaatta cttggattat
     3841 ttccattgtc attccagact taattacaag tattagtact ctaacaaaat ttgatactat
     3901 aacgatacaa gaagttgtta acaatcttga gcacaataaa ctgttagcac gtactattca
     3961 gtatattggt ggcgatggca aacttacaga gacgattgct aactatagtc aacagttatt
     4021 aaagcaattt cttactgttt tgacaaatat tttaacatct gtcacggtta ttgcttctgc
     4081 aattattaat ctttttatta gttttgtttt ttcgttatac gttttagcaa gtaaagaaga
     4141 tctttgtcgt cagggaaata ctttagtaga tacttatact ggtaagtacg ctaaacgcat
     4201 tcattacttg ttagagttgt tgcatcagcg ttttcacgga ttttttgtta gtcagacctt
     4261 agaagctatg attttaggtt cgctgactgc tagtggcatg tttatattaa gattaccatt
     4321 tgcagggact attggcattt tagtagcttt tacagcattg attccagtta taggtgcttc
     4381 aattggagca gctattggat ttattttaat tatgactcag tccatgtcac aggccattat
     4441 ttttatcatt tttttaatta ttttgcagca gattgaaggc aattttattt atccgaaagt
     4501 agttggtgga tcgattggat taccggctat gtgggtatta atggcaatta caataggcgc
     4561 ttctttaaag ggaatagttg gtatgattat tgcagttcct ttagcagcga cactttatca
     4621 agtgattaaa gataatattc aaaaaagaca agctattcaa aaaaaacaag tttcctaaaa
     4681 ggaacttgtt tttttgtcga ataaaaagat ggaggtaata tgataaatgt attctataaa
     4741 atgtgatgat aataaagcca tgccaagaga acgtttgatg cgactaggag cagagtctct
     4801 aagtaatcaa gaattattag caattttatt acgaacaggt aataaagaaa agcatgtctt
     4861 agagctgtca tcctatcttt tatcgcattt agacagtctg gcagatttta aaaagatgtc
     4921 tttgcaagaa ttacaacatt tggcaggtat aggaaaagtt aaagcgattg aaattaaagc
     4981 tatgattgag ttggtttccc gaattttagc gacagataag acattaactg atagcgtatt
     5041 aaccagtgtt caggtcgctg aaaaaatgat ggcagcttta ggagataaaa aacaagagca
     5101 tttagtcgta ttgtatttag ataatcaaaa tcgtattatt gaagaaaaaa ctatttttat
     5161 tgggactgtc cgacgttcac ttgcagaacc aagagaaatt ttatactatg cctgtaaaaa
     5221 tatggcgact agtctcattg ttattcataa tcatccttca ggaaatattg aacctagttc
     5281 taacgattat tgctttactg aaaaaataaa acgatcatgt gaagatttag gcattatctg
     5341 tctagatcac attatcgtta gttataaaga ttattatagt tttcgagaaa aatcaaccct
     5401 tttttaagtc agaagtcatt gacgaataag cggaacaatt gtagatcttc atctcgaaca
     5461 ccttggagaa gttcaggatg ccactgaaca cctaaaaaag gaatggcatc gttggttgat
     5521 atgactgctt cgatggtacc atcacgtgga tccctagcga ttacttttaa atccttagca
     5581 acagttttta aactttggcg atgaaaagaa ttaattaatg tcttatgacc ataaatagga
     5641 tataagatag agtctggctc aataatcatt tcgtgtgata agaaatcaga aggcgcttct
     5701 tgccaatgtg agtcaatgtg ttggttaaga tttcctccta aggcaacatt cattaactgt
     5761 gtaccacgac aaatccctaa gattggtttt tttaatgtta tagcctcctt gatgatagct
     5821 agctcaaatg tgtctcgctc tggtgaaaaa tcatcatcaa aagcagcctt ctcttcttga
     5881 taatattttg ggtcaacgtt ttgcccacca attaaaatga ttttatcaac catagataca
     5941 taagttttag cggcggcttc atcaccaatg ggtaaaagaa gcggcagccc cccagattga
     6001 gtgactgcct gtacaaatcc agtaggtgca tatgaccatg ggagattatc caaagccata
     6061 tttagtcttt gatttgcagt tattccaata atcggtttgg tcattatacc tccttaatct
     6121 agatgatttt gattcataaa atagagtagt gtctggagct cactggtcaa atcgacagat
     6181 tgaacaataa ctcctttagg aacttgtagg tgaacaggag caaaactcaa gattcctttg
     6241 attcctgctt caataagttg atcagtaact tcttgagcat gaatgctggg aaccgttaag
     6301 atagccgttt caatgtcagt gttcgcaatc cgttctttga cagatgagat accatggact
     6361 ggaatattat cagctgtttt agtaccaaca agagcgttat catcggtatc aaaacccatg
     6421 gcaatttgca tcttattacg atcatggaag cggtaatgta atagagcacg ccctatatta
     6481 ccgcatccaa ctaagataac gtttgttgta gagtgatcat taagcaagtc agcaaaaaaa
     6541 ttcatcaatt tggtaacatc atagccaaac ccacgacgcc ccaattctcc aaaataagaa
     6601 aagtcacggc gtacagtagc agagtcaatt cccattgcat ctgcaatttg tttagaactg
     6661 gctttttcaa cttggtcagc atggaatcgt ttaaaaatac ggtaataaag tgataagcgc
     6721 tttgcagtcg cttttggaat agatttgtca ataaccacta ttttactcct tgtagatttc
     6781 tcgttaaata tgtctgtctt tattgtaaca aaaagattgt gaaaaatgca acattttgat
     6841 tgtttttgta tgagttaaaa aagctaaaat tagttttagc actatataat agtattcatt
     6901 aggaaagtaa gttatgacag tcaaaatgaa caacatgaat taatagcaat agaagcgaaa
     6961 tcatttattg acattgtgat atgactaaaa aaacaaaatt taaagttgat tagacgactg
     7021 ttttgctaaa aatttcacgt tctacaaggc tgtccatca
//
LOCUS       DAUNLR010000071         6964 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUNLR010000071 DAUNLR010000000
VERSION     DAUNLR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6964
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.071"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(95..2413)
                     /gene="pcrA"
                     /locus_tag="VLL59_001623"
     CDS             complement(95..2413)
                     /gene="pcrA"
                     /locus_tag="VLL59_001623"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HER6509735.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
     regulatory      2728..2814
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            2942..4264
                     /locus_tag="VLL59_001624"
     CDS             2942..4264
                     /locus_tag="VLL59_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HER6509736.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     gene            4384..5619
                     /locus_tag="VLL59_001625"
     CDS             4384..5619
                     /locus_tag="VLL59_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HER6509737.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQ
                     ITPIAKRQLHHTHYRIVKM"
     gene            complement(5989..6762)
                     /gene="cfa"
                     /locus_tag="VLL59_001626"
     CDS             complement(5989..6762)
                     /gene="cfa"
                     /locus_tag="VLL59_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HER6509738.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIETTVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
BASE COUNT         1975 a         1360 c         1291 g         2338 t
ORIGIN      
        1 ctaaaactta aaatttttta acttttatat gatacagaaa tctaaaaaaa atgagcttcc
       61 tactcactta tatagtagga agctcatttt tttcttattt tttctcaata ggagcaacac
      121 ttgctagtaa tttctttaaa ccaacttctg gaaatttgat tttcaattcc atcgtttttc
      181 cggagcctga aacctcaagc acagtcccgt ctccccattt tttatggtga gcgatatcgc
      241 caatctgcca agtgacctct tctacagagc tattagaacc aaacggtaaa actgagctag
      301 ttgaagctga tggtatcgta tgtgcctgca ttggctgtgc tgattgtctt acttgagcct
      361 gggcctttcg agcttgtaag gcttctgata ggctcatccc ttgtccaaac tgtgtgtgtg
      421 tttcagtaga aaaacgcaca ccaaatgaag attgtgctgg tcttgccaat cctttataag
      481 agagtagttc ctctgaaatt tctttcaaga agcgtgttgg acggttataa ctacttttac
      541 caaagagggt tctggtgttg gcattggtca taaagagaac ttcttcagct cttgtgattc
      601 cgacataagc taaacgtctt tcttcttcca attcatctgg atcttcagag gcacgtgata
      661 aggggaagac accttcttcc ataccaatta agaaaacaac agggaactcc aagcctttgg
      721 cagcatgtag ggtcattaag gttacttcag cagcttctgc ttgggaatca tctgtatcag
      781 caatcagtgc taaatcgttt aaaaaacgtc ccaagcgatc aacaccggtt tcgtcttctt
      841 cttgagaggc acttgactcg tcaaaatttt tggtaacaga taagaattct tcgatatttt
      901 cgatacgggc ttggctttcc aatgtatttt gcaggcgtaa gctatctaaa taacctgttt
      961 tttctaacaa agcttctgct aagtcggtga tactcatctg atctaggtct tgacgtagct
     1021 gaccgagaat attggccaag tccatgatag cttgtgctgc tttacctttc aagggggaca
     1081 tcaatagatt tgaagctgct tctaataaag actggtcact ctcataggca aactgacgca
     1141 gtttatcaag cgttcctgga ccaacacctc gtttaggctc attcacaatc cgctcaaaag
     1201 aaatattatc agcagggtta gcaacaatgg ttaaataggc aatcaaatcc cgaatttctt
     1261 tacggctgta aaacttggtg cctccaacca tggtgtaagg aatattggat tttaagagtg
     1321 cttcttcaat ggtccgagat tgggcattgg tacggtataa aacagcgaaa tctttgaagt
     1381 tttttccaag ctcttgactc atattgctaa tggttgaggc cacaaatact gcctcatctc
     1441 gctcatcatt tgcccggtaa taaaccagtt gttcaccatc cgcattttgt gtccaaagtt
     1501 tcttaggacg gcgattacgg ttattgttaa tcacgtcgtt agctgcttgc agaattttct
     1561 tggtagagcg atagttttct tctaaaagca ctaccttagc atctgggtaa tctttttcaa
     1621 aatcaagaat attttgcatg tcagctcccc gccaaccata gatagactga tcagcgtctc
     1681 caacaacgca aatattttta aagcgagaag ctagtaattt aattagctga tattgagcat
     1741 ggttggtatc ttggtactca tccacatgaa tgtattggta acgctgctgg taataagcta
     1801 acacgtcagg attagcgtca aacaggcgta gcgtcatcat gattaaatca tcaaagtcaa
     1861 gtgcttcgct acgtcgtaat tcttcctgat aagctttgta acacctcgct acgatttgac
     1921 tatacatatc agcagcctgt gcctcgtatc ccttttcatc aagcaaatca tttttagcgt
     1981 ttgaaatagt tcctaaaata gaacgttcat tccacttttt agggtctata tttaattgtt
     2041 ttaaaatgcg cttcatcaac gttcgttgct cacctggatc cacgattgtg aagtttcggt
     2101 tgtaaccaat gtgatcagcc tcacgacgca gaatccgtac acacatggag tgaaaggtag
     2161 caattaaggt atctttagta gctggattta aggccaaggc cctttctttc atttcacgcg
     2221 cagccttatt agtaaaggta atagctaaaa tattccaagg attgacaaat ttttcatcaa
     2281 ttaaataggc aatacgatgg gtcagtaccc ttgttttacc agaaccagcc cccgccataa
     2341 tcaataaggg gccttcagtt gtttgaacag cttgtgcctg ccgatcattc attccattta
     2401 ataaaggatt catgctttct ccttaatctc gttcagtgac atctctttta tcaaccttaa
     2461 aattatatca tgtttccaag aaaaatagca aagaagaccc caaaagtaaa gagattcctt
     2521 ttttctagtt taggatcaga tatttaaaaa taatagcgat ttcttaaagc attccttatt
     2581 tttttgctat tttggttgac ttcattcgtt ttttaaggta tgatagtcct aatttaataa
     2641 accgaatgat gtcatgcagg agaagaattt ttttcgccga aggagttata ctctcaggtg
     2701 ttcagttttt gaacgggact gtttgatgga cggacttctg gagagacctt attaggcgcc
     2761 gaaggggcaa ggcatactgc tcaatctctc aggcaaaagg acagaaggta aaatacaaac
     2821 accattaaga acagtcttag tcttttttgt gtttgctgtt ttatcattgc ttcagaagtt
     2881 gtctcaaaga aagagatagc ttttttcttt tggcatcttc gatgactttt aggagagaaa
     2941 gatgatagca ctcgttaaat taattgataa ccttgtttgg gggccgcccc tcttaatttt
     3001 attggttggg acggggattt accttaccag tcgtttagga ttaattcaaa tcttaaaact
     3061 accaagagcc tttaaactca ttttttcaga tgacgaagga catggagata tttcatcctt
     3121 tgctgctctt gcaactgccc ttgccgctac tgtcggaact ggtaacattg ttggggttgc
     3181 cactgctatc aagtctggtg gtcctggagc gctcttttgg atgtgggttg ccgctttttt
     3241 tggaatggcc actaagtacg ctgaaggggt actagcgatt aaataccgta caaaggatgc
     3301 caacggtcat atttctggtg gtcctatgta ctatattgtt aatggcatgg ggacaaaatg
     3361 gaaaccctta gccattcttt ttgcgggttc agggatccta gttgccctat ttggaatagg
     3421 aacctttgct caagtgaact cgatcacctc gtctttaggt catagctttg gcttatcccc
     3481 acaaatggtc agtattgttt tagctatctt tgtggctgcc attatttttg gtggcattca
     3541 ttccatttcc aaagtggctg aaaaagtcgt tccttttatg gctatttttt atattctatc
     3601 tagtttagca gttattttta gtcactacca acagctactt cctgttattc gtttagtctt
     3661 tcaatcagcc ttcactccga cagctgctat tggaggcttt gctggaagtc tcatgaagga
     3721 tgccattcaa aaaggaattg cacgcggtgt cttctccaat gagtctggac taggatctgc
     3781 acctattgct gcagcagcag ctaaaaccaa tgaacccgtg gagcagggac tgatctccat
     3841 gacaggaact tttattgata cgattattat ctgtacccta accggcctat ctattttagt
     3901 aacaggccaa tggactgggc agctcgaagg ggctcctctg acccaatctg cctttgccac
     3961 tgtgtttgga aatttaggga cttttggcct aaccttttcc ctagttctct tcgcctttac
     4021 aacgatttta ggatggagtt attatggaga acgctgcttt gaattcctct ttggcattac
     4081 acatctcacc tacttccgta ttgtctttat cttaatggta ggcctaggag gcttccttaa
     4141 gttagaacta atttgggttt tggctgatat tgtcaatggt ttaatggcac ttcctaacct
     4201 gattgccctc ctagctctct cgccagttgt tattttagaa accaagcatt actttattaa
     4261 gtaaacatga cgttagtact acccagttat acctagtctt cttctgccaa gttcaagacg
     4321 ctaggctttt ttcttaagcc cctttttatg gtataatata aagttgaaat caaaggagtt
     4381 attatgacac aggatccgat tgcaaattta aaactagcca gaaagggccc aatcgttagt
     4441 attattgtct acttgtcgct tagtgttgcc aaattattag ctggttattt gttaaatgca
     4501 agttccctta ttgctgatgg atttaacaat ttatcggata ttgtgggaaa tgtagccctg
     4561 cttattggtc ttcacttagc tagccaacca gccgatgcca atcataaatt tggtcattgg
     4621 aaaattgaag acttatccag ccttgtcact tcttttatta tgtttcttgt aggtttccaa
     4681 gtactgattc acacaattaa aagtatcttt agtggtcagc aagttgatat tgaccctctt
     4741 ggggcgattg tcggtatcgt ttcagctttt gttatgttag gggtttatgt ctttaacaaa
     4801 cgtctttcca aacgtgtaaa atccagtgcc ttagtcgctg cttctaagga taatctagct
     4861 gatgctgtta cttctatcgg aacatcaatt gctattatag cagcttcttt gcatttacca
     4921 gttatcgatc atatagctgc tatgatcatt acgttcttta ttcttaaaac agcttttgat
     4981 atctttatgg aaagttcgtt tagtttatct gatggatttg atagccgtca tttgaaaaaa
     5041 tacgaaaaag ccattttaga aatccctaaa attgtcgccg ttaagtctca acgagctagg
     5101 acctatggta gcaatgtcta tcttgatatt gtacttgaaa tgaatcctga tctttcagtc
     5161 tatgaaagtc actctattac agagaaagtg gagcagttat tgagtgacca attttctatt
     5221 tatgacattg acattcacgt tgagcctgcc atgattcccg aagaagagat ttttgataat
     5281 gtcgccaaaa agctctaccg ctacgaaaaa ttaattttga gtaaggttcc tgactatgac
     5341 cactacattg ctaagtcttt ccaactgatt gatgcgaatg gccaaacagt taactatgaa
     5401 caatttttga accaagaaat ttattatcca agtaacttca accattttca gattgaatcc
     5461 attagtcaaa aaacgatgtt ggtaacttac caattaaatg gcaatcaaca taccagtatt
     5521 tggaggcgtc atgaatcttg gtccttactc ttccaccaaa ttacccctat cgctaagaga
     5581 caattacatc acacacacta tcgtattgta aaaatgtaaa aacattactt ctcttataac
     5641 ataactatac ttcatgatat tcctaaagcg attcctagtc ccaaaatgat aagtgaaata
     5701 gttaaaaaaa tccctacaat ttgtttttaa acagatcata gggatttttt taagaataca
     5761 cgttttcata ttgaatctta ttagtttagg aggttaaaca agattcaata gtgacggttg
     5821 aacaatacct taaattggta catcatgtta aaggcaaaaa gggctacagg tgactcattg
     5881 tttatgagag catcacctca aactctacaa tggtaagata tttaaaatct ttacctattc
     5941 catatcctaa tataatcatc tacctataca acacattact tatacactct atgacttaag
     6001 agctgtttcc aaagcatttt gcacagcaat aacttcatcg tcaacttgtt gaacagtggt
     6061 tgtcggattt agttggacac caaccgcatg tgtgatagct ttgttaagtc tattgtaaac
     6121 gtcaaatggt ttgatcccca aaaccttttt atctctttct aaacgagtgt tccaaatagc
     6181 tttatttagt ttagctttag tatagatagt agcacggtct gttggctgta aatcaggata
     6241 attgataact ttttcctcaa gtgctttaat ttcttgtact tgagctttga tagcgtcaac
     6301 agatgcaaat ggatctataa tacgaatgac taatttagta atagcaaacc ccatatcagt
     6361 atgcgctttt tctactttat gagttaattg ggttgtggaa aatacgattg ctttgatagc
     6421 atctgataat gcttctactc ttgccccaat tgaactaaaa tcatagatcg tttcagtatt
     6481 gaagcgtata gaactcttca tgtgatcaac agcatcgata gctttgttaa cagtagtctc
     6541 aatatcagta cctttagctt catgtttaat agcttctaat tgttgatgtc cctcatcaag
     6601 cttttgcact agagcatctc tttgaagatt cgcttggttg ttattcatta aaatagtatc
     6661 gggatttgaa gcatcatcag ctaaaactga gtgcgtcata gttgaaaata aagctaatcc
     6721 agcaacaact gttgaaagac agagaaggtg tttgggtttc atattattcc tcctgaatat
     6781 aataaaccta tttaaatagt taagtgaagt taaattaatt tataagcgct tataacgtta
     6841 tcatactact tgtttttact aaggtcaata tttctttaat tttcagaaaa taagagaatt
     6901 tcgcaaaaat aatcattttt taatgtcatt aaatgcctag tattactttt aaatggacgt
     6961 taat
//
LOCUS       DAUNLR010000072         6474 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUNLR010000072 DAUNLR010000000
VERSION     DAUNLR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6474
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.072"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(9..2000)
                     /gene="uvrB"
                     /locus_tag="VLL59_001627"
     CDS             complement(9..2000)
                     /gene="uvrB"
                     /locus_tag="VLL59_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HER6509739.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            2193..4367
                     /locus_tag="VLL59_001628"
     CDS             2193..4367
                     /locus_tag="VLL59_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HER6509740.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            4367..5107
                     /locus_tag="VLL59_001629"
     CDS             4367..5107
                     /locus_tag="VLL59_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HER6509741.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            5265..6474
                     /locus_tag="VLL59_001630"
                     /pseudo
     CDS             5265..6474
                     /locus_tag="VLL59_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1927 a         1314 c         1247 g         1986 t
ORIGIN      
        1 ttcaaaacct agtccattaa tttaagttct aaaatcaagt ctcgcatttg agctgccaat
       61 tcgaaatcaa gtaattcagc tgcctcttgc atttgttttt gcagagcatt gatcgcttct
      121 tttcgttctc ctcttgacat actttcataa tccatctctt ctttcgatat atcattgtgg
      181 cttgttttac ttatactaat aaggcctctg atgtcttttt ttatagtttg tggaacgatg
      241 ccgtgcgctt tgttatatgc tatttgaatc tcacgacgac gagccgtttc gtcaatagcc
      301 cgctgcatag aatctgtcat cttgtccgca tacataatga catgaccatc tacgtttcga
      361 gctgctctac cgatggtctg aatcaagccg cgttcattac ggaggaaacc ctctttatca
      421 gcatccaaaa tggctacaag actaacttct ggcacatcaa tcccttcacg gagcagattg
      481 attccaatca agacatcaaa aacaccaagt cgtaaatcac gaataatttc tgtccgctct
      541 aaggttttaa tatcactgtg catatacttg accttgacac ccatctcttt tagataatca
      601 gtcaaatctt ctgccatttt tttagttaag gttgtgatga acgtccgttc atcgcgcgct
      661 acgcgctggt taatttctcc caacaaatca tccatttgcc ccatacttgg ccttacatca
      721 atttcaggat caagtagccc agtcggacga ataatttgct caataattgt attagtctgt
      781 gacatttcgt attcaccagg cgttgctgaa acatagacaa tttggtgcac atgactttca
      841 aattcctcgc gtcttaaggg acgattatca agagctgatg gcaatcgaaa accatagtca
      901 actagcattt gttttctggc ttggtcacca ttatacatgc ctttgatttg tcccattgtc
      961 atgtgacttt catcaatcat aattaaaaaa tcttctggga agaaatctaa caaggtataa
     1021 ggaggttctc ctggtgacct gccatccata tgacgggaat agttttcgac tccgctagta
     1081 tagcccattt cacgtaacat ttcaatatca tattccgttc tttggcgtaa tcgctgtgct
     1141 tctagtagtt taccttcaga ttcaaataac tgtaactgct ctgctaactc tgcttgaatt
     1201 ttggctattg attgctccat atgctcatca tttgttacaa agtgagtagc tggaaataaa
     1261 accaaatggt caacttctcc aatagttttc ccagttaaac tttcgatttc acatatacgg
     1321 tcaatctcat ccccgaaaaa ttccacccga aaagcatgtt catccctgga tgctggaaag
     1381 acctcaacaa catcgccacg tacacgaaaa cagccgcgtt gaaaatcaat atcattacgc
     1441 tcaaattgaa tatctactaa ttgatttagc aaagtgtcac gtgatatctc ctgacctgga
     1501 cgtaggctga ctgctgaatc tgcgtactct tttggcgaac ctagtccata aatacaagat
     1561 acagaagcta ccactatgac atcgttacgc tcaagtaaag aagaggtggc tgaatggcga
     1621 agtttatcga tttcatcatt gactgaacta tctttttcga tataggtgtc gcttgatggg
     1681 acatatgctt caggttggta gtaatcataa taagaaacaa aatattccac agcattgtct
     1741 ggaaaaaatt ctttaaattc accatataat tgtcctgcta aggttttatt gtgagctatc
     1801 actaaggtag gtttatttac tttactaatt acttggctca tggtgtatgt ttttcccgtt
     1861 cctgtagcac ctaggagaat ctgagctttt tctccgccct cgatattatc aactaggctt
     1921 tcaatagctt gtggctgatc accagacggt ttatactttg attttagttt aaatggttta
     1981 tcatcacgtt tatcaatcat tttataccct ctaatagtct tactctctta tagactattt
     2041 taacatagat aagccagaat cacctccaat aagcgtaaaa aacatgtcat ttgcatgtta
     2101 tgttttatga catataaata acaaatttct tgcttaatgt tcaatatttt gttataatta
     2161 accatatttt ttagttttat aaggagatta gtatgacgca caaaataaaa gtattgctgc
     2221 ttgcgataat gtctattttt ttgacatgca atattgcaag tgctgaaact attgctattg
     2281 tttcagatac agcttatgcc ccatttgaat ttaaagactc agatcaaatt tacaaaggaa
     2341 ttgacgttga tattattaat gaagtagcca aacgtcaatc ttgggatttc agtatgagtt
     2401 tcccgggttt tgatgcagct gtaaatgctg ttcaatctgg tcaagcgagt gctctaatgg
     2461 ccggtacaac cattacgaat gctcgtaaga aagtctttca tttctcagag ccatattacg
     2521 ataccaaaat tgtcattgcg acacgtaaag ccaatgccat caaaaaatac agtgacttaa
     2581 aaggaaaaac ggtcggtgtt aaaaatggaa cagcggctca agcctttttg aataactata
     2641 aaaaaaagta tgattatact gttaaaacat ttgacacagg tgatcttatg tataatagtt
     2701 tatctgctgg ttctattgcc gctgttatgg atgatgaggc ggttatccaa tacgcaatca
     2761 gccaaaacca agatattgct attaacatga aaggagagcc cattggaagc tttgggtttg
     2821 ctgtcaaaaa gggaagcgga tatgattatc tagttaatga tttcaataca gctcttaaag
     2881 ctatgaaagc tgatggtacc taccaagcta tcatgaccaa gtggttaggc acagatgata
     2941 aagctaccac cagtcaggca acgggaaatc catctgccaa agctacacct ataaaggaca
     3001 gttataaaat tgtctctgat tcgtcttttg caccttttga atttcaaaat ggtaagggca
     3061 aatacgttgg tattgacata gaattaatca aagctattgc taaacaacaa ggtttcaaaa
     3121 ttgaaatcgc taatccaggt ttcgatgctg ccttaaatgc tgtgcaatct agccaagcag
     3181 atggggtcat tgctggtgca actattactg acgctcgtaa agctatcttt gatttttctg
     3241 atccttatta tacttctaat atcattttag ctgttaaagc tggaaaaaac atcaagaact
     3301 atgaagactt agacagaaaa acagtcggtg ctaaaaacgg cacctcatct tactcttggt
     3361 taaaagaaaa cgctcctaaa tatggttata atgtcaaggc atttgatgat ggttctagca
     3421 tgtatgatag cttaaattca ggttctgtag atgctatcat ggatgatgag gcggttctta
     3481 aatacgctat ctctcaaggt cgtcgctttg aaacacctct tgagggcatt tctactggtg
     3541 aagttggttt tgctgtcaag aaaggaacta atccagaatt aatcgaaatg ttcaacaatg
     3601 gcttagctgc tctcaaaaaa tctggtcagt atgatgacat tatagataaa taccttgact
     3661 ctaagaaagc tgcaactcct tctgaaaaag gtgctgatga gtctactatt tcaggcctat
     3721 tatcaaataa ctacaaacaa ctattggcag gacttggaac cacgctcagt ttaaccctta
     3781 tttcatttgc tattgctata attatcggga tcatctttgg gatgatggcc gtgtcaccaa
     3841 ctaaatcact tcgactcatt tcaacggtct ttgtggacgt tgttcgaggg attcctttga
     3901 tgattgtggc tgccttcatt ttctggggag taccaaacct tatcgagagt atgaccggcc
     3961 accagtcacc aattaatgat ttcttagctg ctacaattgc actgtcactt aatggcggag
     4021 cctatattgc tgaaattgtt cgcggtggta tcgaagctgt tccagcaggg caaatggaag
     4081 ctagtcgaag tcttgggttg tcttacggaa ccacgatgag aaaagtaatt ctcccacaag
     4141 ctgtgaaact aatgttacct aactttatca atcagtttgt tatttcattg aaggatacaa
     4201 caatcgtctc agcaattggt ttagtggaac tcttccaaac aggtaaaatc attattgcta
     4261 gaaattacca gtcgttccgt atgtatgcta ttttagcaat tatttacctt atcatgatta
     4321 cactcttaac aagacttgca aaacgtttag aaaagaggct taactaatga cagaattaaa
     4381 aattgatgtt caagatttac acaaatctta tggtcaaaat gaagtcttaa aaggaattga
     4441 tgccaaattc tacgaaggtg atgtcgtttg tatcattggt ccttctggtt ctgggaaatc
     4501 aacctttcta cgtaccctca accttctaga gacgattacc agtgggaagg tcatggtgga
     4561 cggttttgaa ttatcagatc ctaagactaa tattgacaag gcacgtgaaa atattgggat
     4621 ggtattccaa cacttcaacc ttttccctca catgactgtt cttgagaata ttatctttgc
     4681 tcctgttgaa ttaggtaaag agtctaaaga agttgctaaa aagcatggca tggcacttct
     4741 agaaaaagtc ggactttctg ataaggccga cgccttccca ggaagtttat ccggcgggca
     4801 aaaacagcgt gtcgccatcg ccagaagttt agcaatgaac ccagatatta tgctctttga
     4861 tgaaccaact tctgctcttg accccgaaat ggttggggac gttttgaacg ttatgaaaga
     4921 cttggcagaa caaggcatga ccatgttaat tgttactcac gaaatgggat ttgctcgcca
     4981 agtagctaac cgtgttatct ttacagacgg tggtcaattc ttggaggatg gtactcctga
     5041 agagattttt gatcatccta agcaccctcg tctcattgaa tttttagaca aggtcttaaa
     5101 cgtctaatag agcagacacc atactaactt ccaaaaaata ataaggcaag gaaacaggtt
     5161 tccttgcctc agactgaaga caaagtcctt agaatcactt ttctaggggc ttttcatgat
     5221 atttaggagt ataatataag aaaaaggact tgtgaggttc tcctatgtta cacaaagaaa
     5281 aacctgacta taaccgcaat cagtacggtt tctataccct tgaccagtta gtgcctgatg
     5341 aacatttcct gcgccaagtg gaagctgtga ttgacttcga cttcatctat gacctagtag
     5401 aagacaccta ttcgtctgat aatggtcgcc ctagccttga tcctgtcatg ttggttaaaa
     5461 tccctctgat tcagtgcttt tatggcattc gttccatgcg tcagaccatc aaggatattg
     5521 aagtgaatac tgcctatcgc tggtttttag gtttgacttt ggatgacaag gtgccacatt
     5581 tcacaaccta tggcaaaaat tattcccgtc gctttcaaga aaaaggcttg attgagtcca
     5641 tttttacgca tattcttggg ctatgtatca atacaggcct gattgacccg acggagattt
     5701 tcatagatgg gactcatatt aaggctgcgg ctaataatcg caagttcatc aaccgagagg
     5761 tggaaaaaca agccaagttc atgagtgaac agctagaaat cgaaatcaat cgggataggg
     5821 agaagcatgg aaaaaagccg ctagggcccg ccaaagagct agagcccgtc gctaagaaaa
     5881 tctccacaac cgatccagaa agtggctggt ttcacaaagg tgatcataag gaagtcttcg
     5941 tttattctgc tcaggtggct tgtgacaagt atggatgggc ttgcttatag tgttgaggct
     6001 ggcaatatcc atgatagtca ggcttttcct gcactttttg ccaagcttga acccttgaaa
     6061 ccacagttta ttattgcgga ttccggctat aacattccca gcattgccaa gtttctgatt
     6121 gataaggaga tcactcctgt ccttccttac acacgaccaa gaggaaagaa agaccttcta
     6181 cgtccgaaag aattgattta tgatgagcac tttgattgtg tcatctgccc tgaacatcaa
     6241 gccttgacct accgcactac gaccagagaa ggctaccgag aatacaaaag tgaccctgca
     6301 atttgtgcca attgtcccct gttatctgta tgtacgacca gtaagaacta ccaaaaagtt
     6361 gtcacacggc atatttggaa agactatttg gcacagccaa ggaataccac aatctccgct
     6421 atacgagaga gaaaggcaag tccaaaatgg aagataaggt tggactgact ttgg
//
LOCUS       DAUNLR010000073         6074 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUNLR010000073 DAUNLR010000000
VERSION     DAUNLR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6074
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.073"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            76..1530
                     /locus_tag="VLL59_001631"
     CDS             76..1530
                     /locus_tag="VLL59_001631"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HER6509742.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            1648..2511
                     /locus_tag="VLL59_001632"
     CDS             1648..2511
                     /locus_tag="VLL59_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HER6509743.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            2540..3190
                     /locus_tag="VLL59_001633"
     CDS             2540..3190
                     /locus_tag="VLL59_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HER6509744.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLSLLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            3323..3976
                     /locus_tag="VLL59_001634"
     CDS             3323..3976
                     /locus_tag="VLL59_001634"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HER6509745.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            4108..5376
                     /locus_tag="VLL59_001635"
     CDS             4108..5376
                     /locus_tag="VLL59_001635"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HER6509746.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTTAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(5437..>6074)
                     /gene="plsY"
                     /locus_tag="VLL59_001636"
     CDS             complement(5437..>6074)
                     /gene="plsY"
                     /locus_tag="VLL59_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HER6509747.1"
                     /translation="LLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNTFR
                     ILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKGGK
                     AVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIHFL
                     LPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
BASE COUNT         1923 a         1116 c         1244 g         1791 t
ORIGIN      
        1 tggtggtttt cttttatttg tgttttaata aaaaagaatg ttttaggatt catatcttag
       61 aaaggaagag tagctatgac ttatcaagat gcgacggcta tggctattgc tgttcagact
      121 ggtcagacca caccactaga attagtaacc caggctattt ataaggctaa aaagttgaac
      181 cctaccttaa atgctattac ctcagaacgc tttgaagcag ccctagaaga agccaaacaa
      241 agggattttt caggtctgcc ttttgctggt gtgcctcttt ttttaaaaga tttgggacaa
      301 gaattaaaag gtcactcatc aacctcaggt tccagattgt ttaaagagta tcaagcaact
      361 aaaacggatt tatttgtgaa aagattagaa gctttaggct ttattatttt agggcgctcc
      421 aacacgcctg aatttggctt taaaaatatt agcgatagca gtttgcacgg accagtgaat
      481 ttaccaaagg ataatacacg aaatgctggt ggctcatctg ggggagctgc tgctctagtg
      541 tcatcaggaa ttagtgcgct agcaactgct agtgatggtg gtggttctat tcgaattcca
      601 gcctcgttta acggcttaat tgggctcaaa cctagccgtg ggcgcatgcc tgtcggacct
      661 ggttcttatc gaagctggca aggagcctca gttcattttg ccttgaccaa atccgttaga
      721 gatactagaa atctactcta ctatttacag atggaacaaa tggaaagccc cttcccccta
      781 gccaccttaa caaaagatag tatttatcaa tcgctacaac gtcccttgac aattgctttt
      841 tatcaacggt taagtgacgg tagcccagta tctttagata ctgcaaaagc tttaagacaa
      901 gcagtaactt ggctaagaga acaagggcat cagctagttg aattggaaga gtttcctgta
      961 aatatgacag aagtgattcg tcattattat attatgaata gtgtggaaac ggctgctatg
     1021 tttgctgata ttgaagacac ttttggacgt ccgatgacca aagacgatat ggaaaccatg
     1081 acctgggcta tttaccaatc aggtaaagac atcccagctt ggcgttactc acaggtcctt
     1141 caaaaatggg atacgtacag tgcaaccatg gctagttttc atgagactta tgacctgttg
     1201 ttgacgttca caaccaacac accagctcct aagcacggag aacttgtccc agattcgaaa
     1261 ctcatggcta acttggctca agctgaaatt ttcagcagtg aagagcaatt caatttggtc
     1321 gaaaccatgt ttggtaagag tctggctatt aatccttaca cagctctgcc taatctaact
     1381 ggccagccag ctattagttt acctacttac gaaactaagg aagggctccc aatgggcatt
     1441 caactaattg cagccaaagg tagagaggac ctattattag gaattgcaga gcagtttgag
     1501 gcagcaggat tattgaagat tcctcaataa taatcttata aaacagttta actattatag
     1561 attaactttt taaagagatt gagcgctcac tgataacaca acttaatcaa aatgttatac
     1621 tattcttatc ttaataaagg agttactatg aagaaatcag ttactttact gtctatcgga
     1681 cttgccagcc ttttattggc agcatgtgcg ccacataaat ctcaaaaatc aagttgggac
     1741 actatcaaag aaaaaggggt gttaaaagta gctaccccag gaacctatca gccaacttct
     1801 ttttacaacg ataataatga gttagtaggt tacgaagtag atatggtcaa agaaatcggt
     1861 aaacgactta acattaaagt caagtttgtt gaaacaggat ttgaccaagc gtttacctca
     1921 gttgatagtg gtcgagtgga tatttctttg aacaactttg acattacccc aaaacgtcag
     1981 aaaaaataca atatctctac gccttataaa tacggggtag gaggcatgat tgtccgtgct
     2041 gatggcagct caaacatggc taaaaaagat cttagcgact ggaaaggaaa aaaagcagct
     2101 ggtgcttctg gaacagaata catgaaagta gcgcaaaaac agggagccga actggtgacc
     2161 tacgataatg ttacaggaga tgtttatcta aacgatgtgg ctaacggtcg aacagatttc
     2221 attccaaatg attacccagc tcaaaaatta tttgtggatt acatgttatc tcaaaatcca
     2281 aatctaaatg tcaaaatgag cgatgttcag tacaacccaa ccgaacaagg aattgttatg
     2341 aacaaaaaag acgatagcct caagaaaaaa atagatgctg ttattaaaga catgataaaa
     2401 gatggtagct tgaagaaaat ctctgaaacc tactatgctg gtcaagatct gacaaaacct
     2461 tttggcaaag acaaaaaaat tcccgtcatt gatacgaaag acgttaacta atacttgatg
     2521 ttaaaggagt cctaaccaca tgattaatat cccattaatg aaagatagtt taggatttgt
     2581 gttatcggga ttaccttata cccttggtat ttcgttgctc agttttttta cgggtctgtt
     2641 tttaggttta ggcctatccc ttctgggaag gtcacgtcag ccgttgattc attatcttgt
     2701 tagagcgtac atctctatta tgcgaggtgt gccgatgatc gtggtgctct ttgttcttta
     2761 tttcgggttg ccttattatg gtttagaatt gccagcttta ctttgcgctt atcttggttt
     2821 ttctatggtt agcgctgcct atatttctga agtttttcgc tcttctatag aagctattga
     2881 caagggacag tgggaagcag ctaaggcttt agggttgcca tatgctctta tggttaagaa
     2941 aattattctt cctcaagctt ttcgaattgc ggttcctcct ctaggcaatg tcattattga
     3001 tatggttaaa agttcgtcgc tagctgccat gattaccgta ccagatattt ttcaaaatgc
     3061 caaaattatt ggcggtagag agtgggatta catgtccatg tatattttag tagcctttat
     3121 ctattggctt attgcttttt tgttagaacg ttaccaagaa ttcttagaaa ataagctagc
     3181 acttgtttaa tatcctgtaa aaaacgaata ttaaccctgg aaatatcata ttttcagggt
     3241 ctttctattt aaaatgtggt aaactagata gaaaaggaca tcgtatttaa cttagaaact
     3301 gacgtgatta gaaaggaatc ttatggctca ttcaatttgg catgagaaaa tcaaatcatt
     3361 tttgccggag cattactacg gtcgcatcaa tcacttttta gatgaagcct atgcttccgg
     3421 tcttgtctat cctccacgag aaaatgtctt taaagcctta caagtcactc ctttggaaga
     3481 aaccaaagtg ttgattttag gacaagaccc ttatcatggc cccaaacagg cccagggctt
     3541 atcattttca gttccagaag agatttctgc tccgccatcc cttattaata ttttaaaaga
     3601 attagcagat gacattggtc ctcgtgacca tcatgattta agcacttggg ctagtcaagg
     3661 ggttctgctt ttgaatgctt gcttaacagt gccagcaggc caggctaatg ggcatgcagg
     3721 cttaatatgg gagccattta cagacgctgt tattaaagtg ctgaatgaga aagacagccc
     3781 tgtagttttc attttgtggg gagcttatgc aaggaagaaa aaagccttca ttactaatcc
     3841 aaagcaccac atcatcgaga gccctcatcc aagccctttg tcatcttatc gtggcttttt
     3901 tggcagcaaa cctttttcaa gaaccaacgc tattttagaa aaagagggca tgactggcgt
     3961 agattggcta aaataagcca gccatttcaa ctaaatagct taagctagac attttgatac
     4021 ctttaataag tgaaatgagc gcagtagatt tttcctatta aagaacgtaa ggtcttatgg
     4081 ttaaaacaga taaataaagg agaaaacatg atactcatca aaaatggacg cgttatggac
     4141 ccgaaatcgc agagagatca agtggcagat gtcttaattg atggtaaaca gattgtaaag
     4201 atagcttcag ctattgaatg ccaagaagct caagtgattg atgctagtgg tcttattgtt
     4261 gccccgggtt tggtcgatat tcatgtgcat tttagagaac ccggtcaaac gcacaaagaa
     4321 gatattcaca cgggagcctt ggcagcagca gcaggtggtg tgactacggt tgtcatgatg
     4381 gctaatacca atcctgtcat ttcagatgtc gaaactttac aggaagtgct agctagcgca
     4441 gctaaagaaa agattcatat ttacaccaat gccagtgtca cccaagcctt taatggaaaa
     4501 gacgtgactg attttaaagc tttgttggaa gcaggagcag taagcttttc agatgatggt
     4561 attcccttag aaagttctaa agttttaaaa gaagcctttg atttggctaa tgccaaccaa
     4621 actttcattt ctttgcatga ggaagatcct cagttaaatg gggttcttgg ttttaatgaa
     4681 ggtattgctg aggagcattt tcatttttgt ggggcaactg gtgtagcaga atatagtatg
     4741 attgcaagag atgtcatgat tgcttatgac aggcaagctc atgttcatat ccaacattta
     4801 tctaaagcag aatcggttca agtagtggct tttgctcagc agttgggtgc taaggtaact
     4861 gctgaagtgt ccccacaaca tttttcaaca actgaagatc tcttattgac cgcaggtacc
     4921 agcgcaaaga tgaatcctcc ccttcgtaca caaagagatc gtttagctgt catagaaggc
     4981 ttgaaatcgg gtgttatcac agtcattgcc actgatcatg ctcctcatca caaggatgaa
     5041 aaagctgttg atgatatgac tacagcccca tctggtatga caggacttga aacttctttg
     5101 tcattaggtt tgacgcattt ggttgaacca ggtcatctta cacttatgtc actattagaa
     5161 aaaatgacgc ttaatccagc tttgctttat ggttttgatg cgggttattt ggcagaaaat
     5221 ggtccagcag atttggttat ttttgcagac aagcaagaac gtctgatcac tgagaatttt
     5281 gcttctaaag ctagtaattc cccatttatt ggtaacaaac tcaaaggtgt cgtgaaatac
     5341 actattgcag acggagaggt tgtttaccct aattaacaac aaatgagtta aaacaaaaaa
     5401 gcttgacttt cagagaaagt caggctttta gtaaatttat tttttaggca cttgtttgct
     5461 taaatttagc ccccaaggta ttagattttc agtatgatgt ttgatacgac taatgttatc
     5521 tttgtgtctt ataataataa tgaacgcaag taatatcaca ataaaagtta aaaagtagtc
     5581 ataatttggt aaaagaaaat gaatggcagg aaatgttaaa acagataaca caccaacgat
     5641 agctgaaacc acactagcta aagatatcat actaaataaa tagagaacta aaacaaagat
     5701 agatgctaaa aaaaagagat ataacggagc aaagcctagc aatacaccag cacttgttgc
     5761 tacggcctta ccacctttaa agttggcaaa aataggaaaa gtatgcccta aaactgcgaa
     5821 aaagccgata gcaatggatg aaattgaagt cataccaaaa ataattggta acaatattga
     5881 aagtgtccct ttaaacatat caatagctaa ggtagctgtt cctgccttga cacctaaaat
     5941 ccgaaaagta tttgtggttc cagtatttcc tgatccatgc tctcgtaagt tgatgtggta
     6001 aaagtactgt ccaatccata gtccagttgg aatagaacca agtaaatagg caatggtaat
     6061 aaaaagtagt aatt
//
LOCUS       DAUNLR010000074         6048 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUNLR010000074 DAUNLR010000000
VERSION     DAUNLR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6048
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.074"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..1379
                     /locus_tag="VLL59_001637"
     CDS             <1..1379
                     /locus_tag="VLL59_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HER6509748.1"
                     /translation="LKFISLLFVVSTLLIVFLPKKLEVATIIFILVFGTLSAIISPIN
                     DIPDEYVHYSRTVYISEGDINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKVTKHST
                     REYSYPYIKGTNAYYSFSYIPQALGILVGNALDLPILLTYYFGRLCNLISYAMLAFIA
                     IKLSGSFKQVIAVVTLLPMNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKSNYNT
                     KFFLYLVLCGLLVLSKFTYFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFLFAAM
                     WFRLYGQVKTPYVADFLKEVNVSQQVKNMLESPIVYSSIIIRHMVINLINMNNIFQFG
                     ALSYGITNLFPLYVCFFFFVYISNASKITINIVEKMGIIFVISAIIGATVLAMYLTWT
                     PVGSSTVLGVQSRYLIGIIPLVLLLFSSQQQKFKQIEDILSDKLAIHVSLLFILAMLM
                     STIFRYYH"
     gene            1473..2696
                     /gene="pepT"
                     /locus_tag="VLL59_001638"
     CDS             1473..2696
                     /gene="pepT"
                     /locus_tag="VLL59_001638"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HER6509749.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAHLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            2737..3225
                     /locus_tag="VLL59_001639"
     CDS             2737..3225
                     /locus_tag="VLL59_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HER6509750.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(3212..3409)
                     /locus_tag="VLL59_001640"
     CDS             complement(3212..3409)
                     /locus_tag="VLL59_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HER6509751.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            3458..3934
                     /locus_tag="VLL59_001641"
     CDS             3458..3934
                     /locus_tag="VLL59_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HER6509752.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            3949..4629
                     /locus_tag="VLL59_001642"
     CDS             3949..4629
                     /locus_tag="VLL59_001642"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HER6509753.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    4653..4776
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4791..5321
                     /gene="infC"
                     /locus_tag="VLL59_001643"
     CDS             4791..5321
                     /gene="infC"
                     /locus_tag="VLL59_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HER6509754.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            5363..5560
                     /gene="rpmI"
                     /locus_tag="VLL59_001644"
     CDS             5363..5560
                     /gene="rpmI"
                     /locus_tag="VLL59_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HER6509755.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            5619..5978
                     /gene="rplT"
                     /locus_tag="VLL59_001645"
     CDS             5619..5978
                     /gene="rplT"
                     /locus_tag="VLL59_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HER6509756.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
BASE COUNT         1966 a          989 c         1186 g         1907 t
ORIGIN      
        1 ctttaaaatt tattagtctt ctttttgtgg tgagcacttt actgatagtg tttttaccaa
       61 aaaagttaga ggttgctacg atcattttta ttttagtatt tggaacgcta tctgctatca
      121 tatcacctat aaatgatatt cctgatgaat atgttcatta ttcaaggaca gtttatatct
      181 cagaaggtga tattaatctt accaacaata acaaaaagtt aagaatatcc aaagatgttg
      241 ataagcttat taaacagtca ggaaaaacat ttataacatc aaacttgaaa gtaactaaac
      301 acagcacaag agagtatagc tatccttaca tcaaaggaac taatgcatat tatagttttt
      361 cttatatacc acaagctttg ggtattttag taggaaatgc gctggattta cctatacttt
      421 taacatatta tttcggaaga ttgtgcaacc ttattagcta cgctatgctt gcttttatag
      481 ctatcaagtt gtctggttct tttaaacaag tgatagctgt tgttacttta ctacctatga
      541 acatttattt agcagcatct tttaatcaag acggctttgc tatcggttta gttttagtaa
      601 caattggatt gtttattaac ttgctctcat caaaagataa atctaactat aataccaaat
      661 tcttccttta tttagttcta tgtgggttac tagttctttc aaaattcaca tactttttat
      721 tagtatgcct tccattattt attcctaatg aaaaattcgg aaaaaatacc aagttagtca
      781 tcttgaaaaa attgggagga ctattactca tttttctttt tgctgcaatg tggtttagac
      841 tttatggaca ggttaaaacc ccatatgtcg cggattttct aaaagaagta aacgttagcc
      901 agcaagttaa aaatatgcta gaatccccta tagtctatag cagtattatt attagacata
      961 tggtaattaa tctgattaat atgaataata tttttcagtt tggcgcatta agctatggta
     1021 taacgaacct tttcccgctt tatgtgtgtt tcttcttttt tgtttatatt agtaatgcta
     1081 gtaaaataac tattaatatt gtagaaaaaa tgggtataat ctttgttatt tcagcgatta
     1141 taggtgcaac tgtattagct atgtacctga cttggacacc agtagggtcc tcaactgtct
     1201 taggtgttca aagtcgttat ctgataggaa ttatcccatt agtgttgctt ctttttagta
     1261 gtcaacagca aaagttcaaa caaatagagg atatcctttc tgacaaactg gctattcatg
     1321 tttcgctttt gtttattctc gcaatgttaa tgagtactat ttttagatat tatcattaaa
     1381 ctcttaatta gaggctttaa aaaacttagc ttgaataagt attttaaagc cttttatgct
     1441 ataattaaat tgagaaatta ttgaggtggc ctatgaagta cgataacttg ttagatcgat
     1501 ttataaaata tgtcaaagtg aacacaagaa gcgatccaga cagtgagact actcctagta
     1561 cggagagtca agaagcattt gccttaacga ttttaaagcc tgaaatggag gcaattggtt
     1621 tgcaagatgt tcattataat ccagttaatg gctatcttat tggaactctg cctgccaata
     1681 atccaacctt gacgcgtaaa attggtttta tagcccatat ggatacggct gatttcaatg
     1741 ctgaaaatgt taatccgcag attattgaca attatcaagg aggggacatt acacttggca
     1801 gttctaatta taagttggat ccaaaagcat ttccaaatct taataattat atcggtcaaa
     1861 cattgattac cactgatggg actacacttt taggggcaga tgataaatct ggtattgctg
     1921 aaatcatgac agcaatagaa ttcttaacat cacaaccaca aatagagcac tgtgacatta
     1981 aagtggcttt tggccctgat gaagagattg gggtcggagc tgataagttt gaggtggctg
     2041 attttgaggt ggattttgct tatactatgg atggcggtcc tttaggcgaa ttgcaatatg
     2101 aaactttcag cgctgcagct ctagaagtga cttttttagg cagaaatgtt catcctggta
     2161 cggctaagga tcaaatgatt aatgcccttg agttagcaat agattttcat gagaagctac
     2221 ctgctaaaga gcgacctgaa tacacagatg gttatcaagg cttctatcac ttaacgggac
     2281 taactggaac agttgaagag gcacgcgcat cttacattat tcgtgatttt gaagaagcat
     2341 catttgaagc tagaaaagtg aaagttgaaa atatagctca atcgatgaat gctcatctag
     2401 gaacaaaacg tgtcttggta gagcttaatg accaatacta caatatgaaa aaagttatcg
     2461 aaaaagatat gaccgctatt gagttagcta aagaagtaat ggaagagctt gctatcaagc
     2521 ctgtaatcga acccatacgt ggaggaacag atggctctaa aatttcattt atgggtattc
     2581 ccactcctaa tatttttgca gggggtgaga atatgcacgg gcgttttgag tttgttagct
     2641 tacaaacgat ggagagagct gtcgatgtca ttattggact tgtttgcaaa gcctaattat
     2701 catgtaattg atatttagtg gaaggggctt ataaaaatga ttaaactatt tggtaaaata
     2761 aggtatcact ggcagccaga gttgtcttgg tctattattt attggtctat tgcgtttgca
     2821 cctatttttg taggtttatc tttgttgtat gagcgcactg aaatacctag tcgggttttt
     2881 attctatttg ctatttttgc tgtcctagtt ggcattggat tacatcgtta tttcattatt
     2941 gaaaataatg gtattttaag aatcgtatct tttaaattgt ttggtccacg taagctactt
     3001 atttctacta ttactaagat tgaggtgacc aaatcaacac tttgtctgca cgttgaagat
     3061 aaaagttatc tcttttatat gcgcaaatgg cctaaaaaat attttcttga tgccttagcg
     3121 gttaatccat acttccaagg agaagttata ttaagtgata actttattaa attagactat
     3181 tttgaagttt atcagcatga taaaaaagcc cttactcgag ggtaagagct ttagttgggc
     3241 aagatttgac agctaaaata gcgtccttat ctgaaggaca aattgactga cttgtttcag
     3301 atgagcttga aaatgtgacg ataccattgt catgataatc aaaaagtgat gaataggttt
     3361 ggcatagacc acaagcgatg catttttctg gaatgataga tactttcata actattattc
     3421 taatatgatt ttgttaaatt aacaaggggg gacgatcatg gctaaagaac catgggaaga
     3481 aaaaattgtt gatgatacta tagggacacg aacacgtaaa tcaagaaatg ctttcattag
     3541 cacgccttgg ttgactgctt tattaagtgt attctttgtc atcattgttg ctatactttt
     3601 tattttcttc tatacatcaa atagcggtag taatagacaa gctgaaacaa atggttttta
     3661 tggagcatcc actcataaaa aaacaaggaa agcttctaac gctaaaaaaa catcaagtag
     3721 ttcaacaact acagacacaa caccttctag cgaagaaaca cttgcttcta gtgaaggaac
     3781 tggcgaaacc cttactgtat tggcaggtga gggggcagct tctattgcag ctcgtgcagg
     3841 tatttctgtg gagcagttac aagcacttaa tccagagcac atgactcaag gatattggta
     3901 tgccaatcca ggagatcaag tcactattaa ataattgaag aggaaaaaat gaaagcaatt
     3961 aaaattgcga ttgatgggcc agcttcaagt ggaaaaagta cagtagccaa gattattgca
     4021 aaaaatcttg gctatactta tctagatact ggtgctatgt atcgctcagc aacttatatc
     4081 gcactgacac atggctatac gggtaaagaa gtagccctta ttttagagga acttgagaaa
     4141 aatcctattt cctttaaaaa agcaaaagat ggctcccaat tagtttttct tggggatgag
     4201 gacgtgacct tagccattag gcaaaatgat gtgactaaca atgtttcttg ggtctcagct
     4261 ttgccagaaa ttagagaaga gctggttcat caacaaagac gcattgcaca agctggtggc
     4321 attatcatgg atggtcgtga cattggaacg gttgttctcc cagatgcgga actaaaaatc
     4381 tttttagtgg cttctgtcga agagcgggca gagcgccgct ataaagaaaa cctagaaaaa
     4441 ggaattgaat cagattttga gacgctaaaa gaagagattg cagctcgtga ttacaaggat
     4501 agtcatcgta aggtttcacc tctaaaagca gctgaagatg cccttatttt tgataccaca
     4561 ggtgtttcta ttgatggcgt ggtgcaattt atccaagaaa aagcagaaaa aatagttgac
     4621 atgtcctaga gcctatgtta gaatagtaac aatgagaaaa gtagaagtga gagcttctcg
     4681 ccttgcgact taggttgtct ggccctaaca tgtcaaattc ctatggaata ttatgtgtgc
     4741 gggcttgatt tatcaagtcc gctttcgttt ttctctaaaa aaataaagag gtgaagatca
     4801 tagctaaaaa ggatctattc attaatgatg aaattcgcgt tcgcgaagtt cgtctcgttg
     4861 gtcttgaagg tgaacaatta ggtattaaac cattgtctga agcgcaatca ttggctgatg
     4921 cttcaaatgt tgatttggtt ttaatccagc cacaagctgt tcctcctgtt gccaaactta
     4981 tggactatgg aaagttcaaa tttgagtatc aaaagaaaca gaaagaacaa cgtaaaaaac
     5041 aaagcgttgt gactgtgaaa gaagttcgtc tcagtccagt tatcgataaa ggtgactttg
     5101 aaacaaaact tcgtaacggt cgtaaattcc ttgaaaaagg aaataaagtt aaggtttcta
     5161 ttcgtttcaa aggacgtatg attactcata aagagattgg tgccaaggta ctagctgact
     5221 ttgctgaagc gactcaagat attgctatca ttgagcaacg agcaaaaatg gatggacgcc
     5281 aaatgtttat gcaacttgca ccaatttcag acaagaagta attgtcacag tttcattata
     5341 tctttaagag gagaatacta aaatgccaaa acaaaaaaca caccgcgcat cagctaaacg
     5401 ttttaaacgt acaggttcag gcggtttgaa acgcttccgc gcctttacat cacaccgttt
     5461 ccacggaaaa actaaaaaac aacgtcgtca tcttcgtaaa gccggtttgg ttagctcagg
     5521 agatttcaaa cgtatcaaag caatggttac tggtctttaa ttttaaaggc agtagacatt
     5581 tacgagtatt ataagaatta tttgaaggag aactattaat ggcacgtgtt aaaggtggcg
     5641 ttgtttcacg caaacgtcgt aaacgtattt taaaattagc taaaggttac tatggagcaa
     5701 aacacatctt gttccgtact gcaaaagagc aagtgatgaa ctcttactac tatgcatacc
     5761 gtgatcgccg tcagaaaaaa cgtgatttcc gtaaactatg gatcactcgt atcaatgcgg
     5821 ctgctcgtat gaacggtttg tcatactcac aattgatgca cggtttgaaa cttgctgaaa
     5881 tcgaagtaaa ccgtaaaatg cttgctgatt tagcagtagc tgatgcagca gctttcacag
     5941 ctcttgctga tgcagccaaa gcaaaacttg gcaaataaga aacgctatac ctaaaaaata
     6001 actttctatt acctatagaa agttataaag aaacaaaaat gaaggaga
//
LOCUS       DAUNLR010000075         5635 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUNLR010000075 DAUNLR010000000
VERSION     DAUNLR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5635
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.075"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            348..>5635
                     /locus_tag="VLL59_001646"
     CDS             348..>5635
                     /locus_tag="VLL59_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HER6509757.1"
                     /translation="MFLKHQDVKQKNWRMRKVKKVFVSSCMLLTVGLGVAVPTGFSQS
                     NGVMVVKAAEVSEEVSKLPTVSFVKQNPEGSDTSKRVLWGPEVDKTYSKHAAGSDQRK
                     YYDNDVKAPVLRVGILGSSTNGGIEISAPVYSNTNYTLRVNLAHQMTWVRLGYKGAVK
                     TGEYYEKTKSNKLYTHEMRLVTSNKKHVYQGEGSEGKLTMYVYRDNRVDGKNNSAAII
                     KDAILVPDTPKLVPQNKELELKLSKVENKSIQSIVNEIPEVSKILDSLVTDSAHFNNP
                     VKSTWSKIDNPDKVITTVDDSFVLNYTAEKWGQNTSGKVTVRLIEDRDYKKDIDLAKQ
                     SLLDIKKKTIKQIDLDNWLSDDEKRDQTSEVERTYTEGESEINKAKTLTTIHDVLKKY
                     STEGNNISIPDQYKKGKKEAKVSQEKEKLQSVYDTEKNKIVQDKWSSTSQKQEEQRLL
                     DSVKTEAENNLSETNSLQDLLSKSPSEQDKLRKIYKGNKEQKVREDGLKNLKKTLLDT
                     QIAIKEDNWLSNGAKKMQLTAAQKAFEKGAKELQNSQDFATHEEKFNNYVSKDTEKHP
                     DSIPNQYIPGNQEEIKSKEKVNLKKVYDDTISNINQDNWLSDEDKQKQTAQATQAYEN
                     GIQDISSADSLINLKQVVEKSVGNEDETSIPNKHIKGDQKKEVDSATQKLQEIHKKTQ
                     DAIETDPWLSPEQKKAQKENAKARLDAGLKAVETTESLDKLKEVESDFLDKEKAESIP
                     SQHQAGTPEVARKTFLDNFEKEAKKEIESIDKDDTLTANAKQVAKDKVAQQLQEATAK
                     VEKAQSFDDLKKVETEFVPALPHTKGEKLNQQQTEAISGLEGVQKATEKAISEDKTLS
                     KDEKKKQIADSKERLKSDTQKVKDAKNADAIKKAFEEGKVNIPQAHIPGDLNKDKEKL
                     LAELKQKADDTEKAIDSDKTLTAKEKEEQKAKTKEELQKATEAVGAIDNREELDEKVP
                     ELKKAIEDTHVKGNLEGVKNKAIEDLKKVHDETVAKINGDDTLDKATKEAQVKEADKA
                     LAAGKEAITKADDADKVSTAVTEHTPKIKAAHKTGDLKKAQEEANTALDKAAEKEREE
                     INNDITLTAKDKEQQLKEVETALTKAKDNVKAAKTADAINDARDKGVATIDAVHKAGQ
                     DLGARKSGQVAKLEEAAKETKDKISADPTLTSKEKEEQSKAVDAELKKAIEAVNAADT
                     ADKVDDALGKGVTDIKNQHKTGDPVVARREAHGKQLDRVAQETKDAIEKDPTLTTEEK
                     AKQVKDVDAAKERGMAKLNEAKDADALDKAYGDGVTSIKNQHKSGDPIEARRGLHNKS
                     IDEVAQATKDAITADTTLTEAEKETQRGNVDKEATKAKEELAKAKDADALDKAYGDGV
                     TSIKNQHKSGKGLDVRKDEHKKALEAVAKRVTAEIEADPTLTPEVREQQKAEVQKELE
                     LATDKIAEAKDADEADKAYGDGVTAIENAHVIGKGIEARKDLAKKDLAEAAAKTKALI
                     IEDKTLTDDQRKEQLLGVDTEYAKGIENIDAAKDAAGVDKAYSDGVRDILAQYKEGQN
                     LNDRRNAAKEFLLKEADKVTKLINDDPTLTHDQKVDQINKVEQAKLDAIKSVDDAQTA
                     DAINDALGKGIENINSQYQHGDGVDVRKATAKGDLEKEAAKVKALIAKDPTLTQADKD
                     KQTAAVDAAKNTAIAAVDKATTADGVNQELGKGITAINKAYRPGEGVKARKEAAKADL
                     EKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTA"
BASE COUNT         2240 a          904 c         1178 g         1313 t
ORIGIN      
        1 agcaaaatgc agctgaatat tcttaatttt aggtatgaaa aagcgtcggg attgataaaa
       61 aatctattga attgggtaaa tttaagttga tataataagt tgattagaaa aattaataat
      121 tcatttaaat tctaattagc tgtaacgttc cggggcgtgt taaactgtct gaacatagaa
      181 aatacaggtt tctaaggtga ctaaaataag ttaaggagga ttccttaaat tctgtgatag
      241 gaacgtaaac tctctacaag agtagagcac gtcatcagtc agtctgggtg tctactggct
      301 gacaacgtca aataagatag gcatgaaaaa ataaggggga atacagaatg tttttaaaac
      361 accaagatgt gaaacaaaaa aattggagaa tgcgtaaggt caaaaaagtc tttgttagtt
      421 catgtatgct tttaacagta ggcctcggag ttgccgtacc tactggattc agccaatcta
      481 atggcgtgat ggtcgtaaag gctgcggaag tttcagaaga agtaagtaaa ttgccaactg
      541 ttagttttgt caaacaaaat ccagaaggtt ctgatacctc aaagcgggtt ttatggggac
      601 cggaagttga caaaacttat tcaaagcatg ctgcaggatc tgaccagaga aaatattatg
      661 ataatgatgt gaaagcacca gttcttagag taggaattct tggtagttct acaaatggag
      721 gtattgaaat atctgcgcct gtttatagta atactaatta tactctaaga gttaatttgg
      781 cacatcaaat gacctgggta agattaggct ataagggtgc tgtgaaaact ggagaatatt
      841 acgaaaaaac caaaagtaac aaactttata ctcatgagat gagattagta acttcaaaca
      901 agaaacatgt ttatcaaggt gaaggttctg aaggaaaatt aaccatgtat gtttataggg
      961 ataacagagt tgatggaaaa aataattcag cagccatcat taaagatgct attttagttc
     1021 cagatactcc taaattagtc cctcaaaata aagaattgga attaaagtta tcgaaagtag
     1081 aaaataaatc tatacaatca atagtaaatg aaataccaga agtttcaaaa attcttgatt
     1141 ctctagttac tgatagcgcc cattttaata atcctgtcaa atctacttgg tctaaaattg
     1201 ataatccaga taaagtgata actactgttg atgattcttt tgttcttaat tatactgctg
     1261 aaaaatgggg gcaaaatact tcgggtaagg ttactgttcg cttgatagag gatcgtgact
     1321 ataaaaaaga tattgattta gctaaacaat cgttattaga tattaagaaa aaaacgatta
     1381 agcaaataga cttagataat tggctgtcag atgatgaaaa gcgagatcaa acttcagaag
     1441 ttgaaagaac ttatactgaa ggtgagtctg aaattaacaa ggcaaaaaca ttgacaacaa
     1501 tacatgatgt cttgaaaaag tattctaccg agggaaataa catctctata cctgatcaat
     1561 ataaaaaagg taaaaaagaa gcaaaagtct ctcaggaaaa agaaaaatta caatctgtct
     1621 atgatacaga gaagaataaa attgtacaag ataagtggtc tagcacaagt cagaagcaag
     1681 aagaacaacg attattagat tctgttaaaa cagaggcaga gaataattta agtgagacga
     1741 acagtttaca ggatttgtta tcaaaatctc cgtcggagca ggataaatta cgtaaaattt
     1801 ataagggaaa taaagagcaa aaagttcgtg aagatggctt gaagaacctt aaaaaaacat
     1861 tgttagacac tcaaattgct attaaagaag ataattggct ctcaaacgga gctaaaaaaa
     1921 tgcaattgac tgcagctcaa aaagcatttg aaaaaggagc taaagaactc caaaattcac
     1981 aagattttgc tacacatgaa gaaaagttta ataactatgt aagtaaagat acagagaaac
     2041 accctgattc aattcctaat cagtatatac ctggaaatca agaagagatt aagtctaaag
     2101 aaaaagttaa tttgaaaaaa gtttatgatg atacaatctc aaatattaat caagacaatt
     2161 ggttgagtga tgaagataaa caaaaacaaa ctgctcaggc aactcaagct tatgaaaatg
     2221 gaattcagga tattagttct gctgatagtt taattaattt gaaacaagtt gtggaaaaat
     2281 ccgttggtaa tgaggatgaa acatctattc caaacaagca catcaaaggc gatcagaaaa
     2341 aagaagttga ctcagcaacg caaaaactcc aagaaattca taaaaagact caggatgcta
     2401 ttgaaacaga tccatggttg agtccggaac agaaaaaagc tcaaaaagaa aacgctaaag
     2461 caagattaga tgcaggtttg aaagctgtcg aaactacaga aagcttagat aaacttaaag
     2521 aagttgagag tgacttcctt gataaagaaa aagcagaatc tattccatct caacatcaag
     2581 caggaactcc tgaagttgct cgcaaaactt tcttagataa ctttgaaaaa gaagctaaaa
     2641 aagagattga atctattgat aaagatgata ccttaacggc aaatgctaaa caagtagcta
     2701 aagataaagt ggcacaacag ctacaagaag ctacagctaa agtagagaaa gcacagtcgt
     2761 ttgatgattt gaagaaagtt gagactgaat ttgtacctgc tttaccgcat acaaaagggg
     2821 aaaaacttaa tcaacaacaa actgaagcta tttctggttt agaaggagtt caaaaggcaa
     2881 cagaaaaagc tatctcagaa gataagacac tgtcaaaaga tgaaaaaaag aaacaaattg
     2941 ctgactctaa ggaacgtttg aaatctgaca cgcaaaaagt taaagatgct aaaaatgctg
     3001 atgctattaa aaaagcattt gaagaaggga aagtgaatat tcctcaagca catatcccag
     3061 gtgatttgaa caaggataaa gaaaaacttc ttgcagagtt gaagcaaaaa gcagatgata
     3121 ctgaaaaagc gattgattcc gataaaactt tgacagcgaa agaaaaagaa gagcaaaaag
     3181 cgaaaacaaa agaagaactt caaaaagcaa cagaagctgt tggagcaatt gacaatcgtg
     3241 aagagctaga tgaaaaagtc ccagaactta agaaagctat tgaagacact cacgttaaag
     3301 gtaatcttga aggtgttaag aataaggcta ttgaagatct taaaaaagtt catgacgaaa
     3361 cagttgctaa gataaatggt gatgataccc ttgacaaagc tactaaagaa gctcaagtga
     3421 aagaagctga caaagctttg gcagcaggta aagaagctat cactaaagca gatgatgctg
     3481 ataaagtaag tacagctgtt acagagcaca caccaaaaat taaagcagca cataaaactg
     3541 gtgatcttaa aaaagctcaa gaagaggcta acacagctct tgacaaagca gctgaaaaag
     3601 aacgtgaaga aatcaataat gatatcacat taacggcaaa agacaaagaa caacaactga
     3661 aagaagttga gacagctctt actaaagcta aagataacgt gaaagctgct aagacagcag
     3721 acgctatcaa tgacgcacgt gataaaggcg tagcaacaat tgatgccgtc cataaagcag
     3781 gtcaagactt aggtgctcgt aagtcaggtc aagtcgctaa acttgaagaa gcagctaaag
     3841 aaacgaaaga caagatttca gctgatccaa ctttgacaag caaagaaaaa gaagagcaat
     3901 ctaaagctgt tgacgctgaa cttaagaaag cgatagaagc tgttaacgca gctgacacag
     3961 ctgacaaggt tgacgatgct cttggtaaag gtgtcacaga catcaagaac caacataaga
     4021 caggtgaccc tgtcgtagct cgtcgtgagg ctcatggtaa gcaacttgat agagtcgctc
     4081 aagaaactaa agatgcgatt gaaaaagacc ctactttgac gactgaagaa aaagctaaac
     4141 aagttaaaga cgtagatgcc gctaaagaaa gaggcatggc taagcttaat gaagctaaag
     4201 atgctgatgc tttagacaaa gcgtacggtg acggtgtgac cagcatcaag aaccaacaca
     4261 agtcaggtga ccctatcgaa gctcgtcgtg gattacacaa caagtcaatc gacgaagtgg
     4321 cgcaagcaac taaggacgct atcacagcag atacgacttt gactgaagct gaaaaagaaa
     4381 cacaacgtgg caatgttgat aaagaagcaa ctaaagctaa agaagaactt gctaaggcta
     4441 aagatgctga tgctttagac aaagcgtacg gtgacggtgt aaccagcatc aagaaccaac
     4501 acaagtcagg taaaggtctt gacgttcgta aagatgagca caagaaagct cttgaagctg
     4561 ttgctaaacg tgtcactgct gaaattgagg ctgatccaac cttaacacca gaagtgagag
     4621 aacaacaaaa agcagaggtt caaaaagagc ttgaacttgc gactgataag attgctgaag
     4681 ctaaagatgc agatgaagca gacaaagctt acggtgacgg tgtcacagcg atcgaaaatg
     4741 cccacgttat tggtaaaggt atcgaagctc gtaaagacct tgctaagaaa gaccttgctg
     4801 aagctgctgc taagacaaaa gctctcatta ttgaagacaa aacgcttact gatgatcaac
     4861 gtaaagaaca gttattaggt gttgatacag agtatgctaa aggtatcgag aatattgatg
     4921 cagctaagga tgctgcaggt gttgataaag catatagtga cggtgttcgt gacatcctgg
     4981 cacagtacaa agaaggtcaa aaccttaatg atcgtcgtaa tgctgccaaa gaatttcttc
     5041 ttaaagaagc agacaaagtg acgaaactaa tcaatgatga tccaaccttg actcatgacc
     5101 aaaaagttga tcaaatcaac aaagttgaac aagctaagtt agacgcaatc aagtctgttg
     5161 atgacgctca aacagctgat gctatcaatg atgctcttgg taagggtatt gaaaacatca
     5221 acagtcaata ccaacatggc gatggcgttg atgttcgtaa agcgactgcc aaaggcgatc
     5281 ttgaaaaaga agctgctaaa gtgaaagctc ttattgctaa ggatccaacc ttgactcaag
     5341 ctgataaaga caagcagaca gcagcggttg acgcagctaa gaatacagca attgcagcgg
     5401 ttgataaagc gacaacagca gatggtgtta accaagaact tggtaaaggc atcacagcta
     5461 tcaacaaagc ttaccgtcca ggtgaaggtg ttaaagcacg taaagaagcc gctaaagctg
     5521 atcttgaaaa agaagctgct aaagtgaaag ctcttattgc taaggatccg accttaactc
     5581 aagctgataa agacaaacaa acagcagcgg ttgacgcagc taagaataca gcaat
//
LOCUS       DAUNLR010000076         5198 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUNLR010000076 DAUNLR010000000
VERSION     DAUNLR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5198
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.076"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            98..1369
                     /locus_tag="VLL59_001647"
     CDS             98..1369
                     /locus_tag="VLL59_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HER6509758.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNMLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNGTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISTGTNTKPEKDSQSKNKKSGVDK"
     gene            1369..2079
                     /locus_tag="VLL59_001648"
     CDS             1369..2079
                     /locus_tag="VLL59_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HER6509759.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            2091..3311
                     /locus_tag="VLL59_001649"
     CDS             2091..3311
                     /locus_tag="VLL59_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HER6509760.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            3565..>5198
                     /locus_tag="VLL59_001650"
     CDS             3565..>5198
                     /locus_tag="VLL59_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HER6509761.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGI"
BASE COUNT         1744 a          779 c         1011 g         1664 t
ORIGIN      
        1 ggcttgtttt cgactaagga ctaagaattt cttgacaaca atataaaaag gtcatatact
       61 tgtcttatac aaatagtaca aaaaggggag gatagaaatg tctaaaagag gaaaaattaa
      121 aataacaacg aaaacaaagc ttattacagc tagtgttata acgctagtat taattataac
      181 tggagtagtc ttgtggaaac aacaacaaaa tatgctaaca gctgatatcg ctaaagaacc
      241 ttactctact gttagtgtaa ctgaagggag tattgcttct tcgactttac tatcaggtac
      301 tgtaaaggct ttatcagagg aatatattta ttttgatgct aataaaggaa atgatgcaac
      361 tgttacagtt aaagtaggtg atcaggtaac gcagggtcag caattagttc aatataatac
      421 aacaacagct cagtcagctt atgatactgc tgttaggagt cttaacaaga ttggccgaca
      481 aattaatcat cttaaaacat acggagttcc tgctgttagt acagaaacta ataaagatga
      541 agctaccggt gaagagacga caacaacagt tcaaccatca gctcagcaaa atgctaatta
      601 taaacagcag ctgcaagatt taaatgatgc ttatgcagac gcacaagcgg aagtaaataa
      661 agcgcagata gcgttaaatg gtacagtagt tatcagtagt gtctctggaa ctgttgtgga
      721 agtaaataat gatattgatc cttcttcaaa gaacagtcaa acacttgttc acgtagcaac
      781 cgaaggacag cttcaggtga aaggaacatt gacagagtat gatttagcaa acgttaaggt
      841 tggtcaatct gtaaaaatta agtctaaagt ttattctaat caagaatgga ctggaaaaat
      901 atcatatgtt tcaaactatc caactgagtc taatgcaggt tcaacaacgc cagcaggtag
      961 cactggagcg ggaagttcta caggagctgc ctatgattac aagattgata ttataagtcc
     1021 tctcaaccag cttaaacaag gtttcactgt ttctgttgag gttgttaatg aagctaaaca
     1081 ggccttagtt cctttaacgg ctgttattaa gaaagataaa aaacactatg tttggactta
     1141 tgatgatgct actggcaaag ccaaaaaagt agaggtgaca cttggaaacg cagatgcaca
     1201 acaacaagaa attcataaag gagtagctgt tggtgacatt gttattgcca atccagataa
     1261 aaatatcaaa ccggataaaa aactagaagg ggttatttca acaggtacca acacaaaacc
     1321 ggaaaaagat tctcaatcaa agaataaaaa atcaggggtg gataaatagt gtcgcatgaa
     1381 aaaaaacaat taatgcaatt atcaaatatt gtgaagagct atcaaaatgg ggatcaagtt
     1441 cttaaagttt tgaaaggtat taatttaaca gtatatgagg gtgaattttt agctattatg
     1501 ggtccgtctg gctcgggaaa atcaacacta atgaatatta ttggtttatt agatcggcca
     1561 acatccggag attacacatt acataatact aaaatagaaa tccttaatga tcgtgaatta
     1621 gcaaaagtac gaaatgatga aatcggcttt gtctttcaac aattctttct gttagctaaa
     1681 ttaactgcat tacaaaatgt tgagttgcct cttatttatg ctggtgtaaa cgtctcaaaa
     1741 agacgtgaac aggctaagca atttcttgaa aaagtaggac ttggacgacg tatcaaacat
     1801 ctaccgtcag aactgtcagg aggtcaaaag caaagggtgg ctatcgcacg agctttagta
     1861 aatgacccat ctattatttt agcggatgaa ccaacaggtg cactagatac taaaacaggt
     1921 cagcaaatta tggaactctt gacagagtta aacaaagaag gtaaaacaat tattatggtt
     1981 actcatgaac cagaaattgc tgattttgca actcggaaaa ttattattcg tgatggtgat
     2041 atcacaacgg atactacagc tagtgttgtt attgactagg aggaaaaata atggaaaatt
     2101 ggaaattcgc tcttagctca atttgggggc ataagatgcg ctcaatcctg acaatgttgg
     2161 gaattatcat cggtgtagca gcagttgtga ttattatggg gttgggaaat gctatgaaaa
     2221 atagtgtaac aagcacattt tctagcaagc aaaaagatat tcaactctat tttcaagaaa
     2281 aaggagaaga agaagacctg tatgccggat tgcacacgca tgaaaataat cacgaagtga
     2341 agccagagtg gttagaacaa attgttaaag atatcgatgg tattgattct tattacttta
     2401 ccaattctgc tacttctact atttcgtatg aaaaaaagaa agtagacaat gcttcgatca
     2461 taggggtaag taaagattat tttaatataa aaaactatga tatcgtagct ggtcgtacac
     2521 taacagataa tgattattct aatttttcgc gtatcattct tttagataca gtattagccg
     2581 atgacctatt tggcgaaggt aattataagt cagctttaaa taaagtggta agtttatctg
     2641 ataaagatta tttagttatt ggtgtttata aaactgatca gacgccagtt tcttttgatg
     2701 gattatcagg cggcgctgtc atggcaaata ctcaggtagc ttcagagttt ggcaccaaag
     2761 aaataggatc tatctacatt catgtgaacg atattcaaaa cagtatgaac ttaggaaatc
     2821 aagcagctga tatgctaacc aacatatcgc atattaaaga tggacagtac gctgttcctg
     2881 ataatagcaa aatcgttgaa gaaatcaata gtcagttcag tatcatgaca acagtcatag
     2941 gttcaattgc agcgatctct cttttagtgg gaggaattgg tgttatgaat attatgttgg
     3001 tatctgtcac agagcgaact agagaaattg gtttacgtaa agcacttggt gcaacacgcc
     3061 tgaaaatttt atcacaattt ttgattgaat ccgttgttct aacagttctt ggaggcttga
     3121 taggattatt attagctcaa ttaagtgtag gggctttagg aaatgcgatg acattaaaag
     3181 gagcttgtat ttctcttgat gtggccttaa tagcagtttt attttctgcc tcaataggtg
     3241 tcttttttgg aatgttgcca gctaataaag ctagtaagtt agatccaatt gaggcattac
     3301 gttatgaata gaatagttcg tatcaattaa tctatagacg ctgactagtt taacgtctga
     3361 ttatatctag tttttgtatt agcacagtag ttatatcatt gaagtgttag tgcatttttt
     3421 gaggtgataa tatctagcaa agctatcatt ggtatgatga tgtggatagc gtataagtga
     3481 tacatctctt atttctagct gaacttcggt tcggctagga agttgtcagg caatgagttg
     3541 tttaaaataa aggagattag ttcaatgaca tttttatctg atttgatatc attaatgaca
     3601 aaaatcagat tatcttgggt aataaaggcg ggtatttttc aattattatt tgtaacgatt
     3661 gctaatattg tcttatcaga atttttctat tttatattag acgttactgg tcaatatcat
     3721 ttagataaag acaatgttgt gactttttta aaaaatccta tagcacttgc tttattaggt
     3781 gcctatttat ttttattagc tgcttttatt caccttgagt tttttgctct atatcgaatt
     3841 attgcggatc aagaaattag tttctatctt tttagaaaac agttttctta ttacctaagg
     3901 gggctttgga aaacattttc tggttaccaa ttattacttt ttttgcttta tatcctactg
     3961 actattccag tcttacatat tggtttatct tctgtgatta ctcaaaagct ttatcttcca
     4021 gaatttattg ttggggaatt atcaaagata actagcacaa agtacttgct ttatggcagt
     4081 cttattcttg tgttttacct taacctaaga ttagtatatt ttttaccatt gatagcaatc
     4141 aaccatcgta cggttgctca agcatggaga gagagttggc aaaagactaa aaagaaacat
     4201 gtattgttat ggatgaaact ttttgcaatc aatggtctta cgcttgtagt cttatcgcta
     4261 gctatttcca tgattcttat ttttgttgat atgtttaatc ctaaggggaa taatattatt
     4321 gttcagctgg gagctttgac ctttacatgg gagctcattt tttttactac tatttttttt
     4381 aaactctgtt cagcgatgat tttaaaagag gcaattgaac cacaaaagca atatgatgag
     4441 ccaagaagaa gtaataaggc atatgttgta atctttatcg tggtgacagt aggttttgct
     4501 tatcaatctc ttgaacgttt aacttttttt gacacatctc actctaagac agttatcgcg
     4561 catagaggac ttgtatcagc aggtgtagaa aattctctgg aagcccttga aggtgctaag
     4621 aaagcaggaa gtgattatgt agaactggat ctaatcttga ctaaggataa tcactttgtg
     4681 gtgtctcatg ataatcgatt gaagcgttta gctggagtaa ataagacgat tcgcaactta
     4741 accttaaaag aagttgaaca tctaacgagt catcaaggac atttttcagg gcgttttgtt
     4801 tcttttgaca ctttttatca aaaggctaag aagttgaata tgccattact tattgaactc
     4861 aagccaattg gtacagaacc tggaaattat gtcgatttgt ttttagaaac ttatcatcga
     4921 cttggtataa gcaaagataa taaagtcatg tctttagatt tagaagtaat agaagctatc
     4981 aagaaaaaaa atccatcaat tacgactggt tatatcatac caattcaatt tggctttttt
     5041 ggagatgaat ttgttgattt ctatgtcatt gaagactttt cttatcggtc ttatttgtcg
     5101 tcccaagctt tttggaataa taaagaaatt tacgtttgga ctattaatga tcccaagcgc
     5161 atagagcatt atctcctaaa gcctattcag ggaattat
//
LOCUS       DAUNLR010000077         5154 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUNLR010000077 DAUNLR010000000
VERSION     DAUNLR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.077"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            101..1649
                     /locus_tag="VLL59_001651"
     rRNA            101..1649
                     /locus_tag="VLL59_001651"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1701..1773
                     /locus_tag="VLL59_001652"
     tRNA            1701..1773
                     /locus_tag="VLL59_001652"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1734..1736,aa:Ala,seq:tgc)
     gene            2072..4974
                     /locus_tag="VLL59_001653"
     rRNA            2072..4974
                     /locus_tag="VLL59_001653"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5060..>5154
                     /gene="rrf"
                     /locus_tag="VLL59_001654"
     rRNA            5060..>5154
                     /gene="rrf"
                     /locus_tag="VLL59_001654"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1462 a         1060 c         1481 g         1151 t
ORIGIN      
        1 agacgaacca aacgtgaggg tgatatggag acatattacc cgtcaagaaa cgagaaataa
       61 atctgtcagc gacagaagga acgagtaagt tcaaacgcaa attaaagaga gtttgatcct
      121 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gagaactggt
      181 gcttgcaccg gttcaaggag ttgcgaacgg gtgagtaacg cgtaggtaac ctacctcata
      241 gcgggggata actattggaa acgatagcta ataccgcata agagagacta acgcatgtta
      301 gtaatttaaa aggggcaatt gctccactat gagatggacc tgcgttgtat tagctagttg
      361 gtgaggtaaa ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
      421 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
      481 tgggggcaac cctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
      541 tctgttgtta gagaagaatg atggtgggag tggaaaatcc accaagtgac ggtaactaac
      601 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
      661 tccggattta ttgggcgtaa agcgagcgca ggcggttttt taagtctgaa gttaaaggca
      721 ttggctcaac caatgtacgc tttggaaact ggagaacttg agtgcagaag gggagagtgg
      781 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
      841 ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
      901 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt aggccctttc cggggcttag
      961 tgccggagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1021 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1081 aagaacctta ccaggtcttg acatcccgat gcccgctcta gagatagagt tttacttcgg
     1141 tacatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     1201 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttaagttggg cactctagcg
     1261 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     1321 gacctgggct acacacgtgc tacaatggtt ggtacaacga gtcgcaagcc ggtgacggca
     1381 agctaatctc ttaaagccaa tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     1441 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     1501 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctatta
     1561 ggagccagcc gcctaaggtg ggatagatga ttggggtgaa gtcgtaacaa ggtagccgta
     1621 tcggaaggtg cggctggatc acctcctttc taaggaaatg gaacacgttt atcgtcttat
     1681 ttagttttga gaggtcttgt ggggccttag ctcagctggg agagcgcctg ctttgcacgc
     1741 aggaggtcag cggttcgatc ccgctaggct ccatcaggat acaatcctac taaacttaat
     1801 acaagtgaag ttgaacacgc aactcacttc ctaggaaaat agacaatctt cgcttgtgtg
     1861 caaggcacac atggtcagat tcctaatttt ctacagaagt ttcgctaaag cgagcgttgc
     1921 ttagtatcct atataatagt ccattgaaaa ttgaatatct atatcaaatt ccacgatcta
     1981 gaaatagatt gtagaaaagt aacaagaaaa taaaccgaaa acgctgtgat tatttaataa
     2041 gttttctagt ttaaaaaaac taggttaata aggttaagtt aataagggcg cacggtggat
     2101 gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt ggggagctgt
     2161 aagtaagcgc tgatccagag atgtccgaat gggggaaccc actaactaat ggttagtatc
     2221 cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta agtagctgca
     2281 ggaagagaaa gcaaacgcga ttgccttagt agcggcgagc gaaacggcag gagggcaaac
     2341 cgaagtgttt acacttcggg gttgtaggac tgcgacgtgg gactttaaaa ggatagaaga
     2401 attacctggg aaggtaagcc aaagagagta acagcctcgt atttaaaatt cttttgagcc
     2461 ctagcagtat cctgagtacg gcgagacacg tgaaatctcg ttggaatctg ggaggaccat
     2521 ctcccaaccc taaatactct ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgatatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtcttaatag ggcgatttag
     2761 tatcatgttg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgaggtaa
     2821 aactcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgatgtt aagtctcttg gaggtagagc actgtttggg tgaggggtcc atctcggatt
     3001 accaatctca gataaactcc gaatgccaac gagatatcat cggcagtcag actgcgagtg
     3061 ctaagatccg tagtcgaaag ggaaacagcc cagaccacca gctaaggtcc caaaataact
     3121 gttaagtgga aaaggatgtg gggttgcaca gacaactagg atgttagctt agaagcagct
     3181 attcattcaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
     3241 ggggctaaaa cagtttaccg aagctgtgga tgacacaaaa gtgtcatggt aggagagcgt
     3301 tctatgtgtg aagaaggtgt accgtgagga gcgctggaac gcatagaagt gagaatgccg
     3361 gtatgagtag cgaaagacag gtgagaatcc tgtccaccgt aagactaagg tttccagggg
     3421 aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt gtatccgatg
     3481 gccaacaggt tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa
     3541 ctaaaccgga cgattggaag agtccggcta agcagtgagg tgtaagatga gtcaaatgct
     3601 tatctttata acattgagct gtgatgggga gcgaatttta gtagcgaagt tagtgatgtc
     3661 acactgccaa gaaaagcttc tagcgtttaa tgatactcta cccgtaccgc aaaccgacac
     3721 aggtagtcga ggcgagtagc ctcaggtgat cgagagaact ctcgttaagg aactcggcaa
     3781 aatgaccccg taacttcggg agaaggggtg ctgacttagg tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagggttta gcgcaagcga agatctgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgggtaagtt ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac
     4081 tcggtgaaat tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc
     4141 atggagcttt actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga
     4201 gccattgact tcgggacgcc agtttcgaat gaggcgttgt tgggatacta cccttgtgtt
     4261 atggctactc taacccagat aggttatccc tatcggagac agtgtctgac gggcagtttg
     4321 actggggcgg tcgcctccta aagagtaacg gaggcgccca aaggttccct cagattggtt
     4381 ggaaatcaat cgcagagtgt aaaggtataa gggagcttga ctgcgagagc tacaactcga
     4441 gcagggacga aagtcgggct tagtgatccg gtggtaccga atggaagggc catcgctcaa
     4501 cggataaaag ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg
     4561 gaggtttggc acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt
     4621 tgggctgttc gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc
     4681 ggtccctatc cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac
     4741 cagagtggac ttaccgctgg tgtaccagtt gtcttgccaa aggcatcgct gggtagctat
     4801 gtagggaagg gataagcgct gaaagcatct aagtgcgaag cccccctcaa gatgagattt
     4861 cccatgattt tatatcagta agagccctga gagatgatca ggtagatagg ttaggagtgt
     4921 aagtgtagcg atacatgtag cggactaata ctaatagctc gaggacttat ccaaaaagaa
     4981 atattgacaa cgttacggat tcttgttaga ctataggtat tcaattttga gtgggttatg
     5041 aaaatagcac atttacaagt taagtgacga tagcctagga gatacacctg tacccatgcc
     5101 gaacacagca gttaagccct agaacgcctg atgtagttgg gggttgcccc ctgt
//
LOCUS       DAUNLR010000078         4894 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUNLR010000078 DAUNLR010000000
VERSION     DAUNLR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4894
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.078"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     misc_feature    <1..124
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            153..653
                     /locus_tag="VLL59_001655"
     CDS             153..653
                     /locus_tag="VLL59_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HER6509762.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            718..1083
                     /gene="rplL"
                     /locus_tag="VLL59_001656"
     CDS             718..1083
                     /gene="rplL"
                     /locus_tag="VLL59_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HER6509763.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            1342..1941
                     /locus_tag="VLL59_001657"
                     /pseudo
     CDS             1342..1941
                     /locus_tag="VLL59_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            2116..2441
                     /locus_tag="VLL59_001658"
                     /pseudo
     CDS             2116..2441
                     /locus_tag="VLL59_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            2432..2706
                     /locus_tag="VLL59_001659"
                     /pseudo
     CDS             2432..2706
                     /locus_tag="VLL59_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2752..2964
                     /locus_tag="VLL59_001660"
     CDS             2752..2964
                     /locus_tag="VLL59_001660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509764.1"
                     /translation="MMTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLL
                     NRANSLEELLLKAKEVNLTIDLKQKM"
     gene            3230..3925
                     /locus_tag="VLL59_001661"
     CDS             3230..3925
                     /locus_tag="VLL59_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
                     /protein_id="HER6509765.1"
                     /translation="MEHQIERLIAEDIYIKVSFGVKQSGLIFIPNYQLDIRKEENHKK
                     YKVYIRETAQFFIYNKEASELNRYMRGHELIYQLTNDSKSIPKRRRQTIDTLKKKIEE
                     ISLLIELDTENKPYQDIKDDIVKDMAQLDLTITELQDHIAHLNKVAEVLLNLNNNDIE
                     NRRLARYDYAKMNLTAAIKIEEVEKEIETSQNELNISIDEYEYLVRRLEKFGEILSDS
                     KIIDTSRNEIQWE"
     gene            4076..4762
                     /locus_tag="VLL59_001662"
     CDS             4076..4762
                     /locus_tag="VLL59_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HER6509766.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
BASE COUNT         1689 a          735 c         1020 g         1450 t
ORIGIN      
        1 aactgaccta agacagcagg ggagcatgct cataatattc ctgccgaggc acaaaacgtg
       61 attaaagaaa ataacgtatt tgtactttcg tgtctaggtt taggtgcgat ttttttgtac
      121 ctagcccaaa aataaaaacg gaggtaaaac taatgagtga agcaattatt gctaaaaaag
      181 ctgaacaagt cgaacttatt gctgagaaaa tgaaagcagc agcaagtatc gttgttgttg
      241 attcacgtgg tcttacagtt gatcaagata ctgttcttcg tcgttcactt cgtgaaagtg
      301 gcgttgagtt caaagttatc aaaaactcaa ttttgactcg tgcagctgaa aaagcaggtc
      361 ttgatgagtt gaaagatgta ttcgtaggac catctgcagt agcattttct aacgaagatg
      421 ttatcgcacc agctaaagtt atcaacgact ttactaaaac tgctgacgca cttgaaatca
      481 aaggtggtgc aatcgaaggc gctgtttctt caaaagaaga aatccaagca cttgcaacat
      541 tgccaaaccg cgaaggaatg ctttctatgc ttctttctgt acttcaagct ccagtccgca
      601 acgttgcata cgctgtcaaa gctgttgcag aaaacaaaga aggcgctgct taagacgtct
      661 cagagtagct taaggctacg cttaacattt taaattaatt atttggagga aatcacaatg
      721 gcattgaaca ttgaaaacat tattgctgaa attaaagaag cttcaatcct tgagcttaac
      781 gatcttgtaa aagctatcga agaagaattt ggtgtaactg cagctgctcc tgtagctgct
      841 gcagctgctg gtggtgctga agaagctgct aaagattcat tcgacgttga attgacatct
      901 gctggcgaca aaaaagttgg cgttatcaaa gctgttcgtg aaatcacagg tcttggtctt
      961 aaagaagcta aaggtcttgt tgatggagca cctgctaacg ttaaagaagg cgttgctgct
     1021 gcagaagctg aagaaatcaa agctaaactt gaagaagctg gagcaacaat cactcttaaa
     1081 taagaagcag atagcaattt gagagcgaaa tcccgattta tcagtctttt agagcttata
     1141 gcgatttgaa gaaactgata aaatgatttg gttttttgcc aaaaatcctg cccaaaaaat
     1201 ctttggcagg atttttattt tctataaaaa ttaagctgag tagagtggtt attctatcta
     1261 tatgtgtcta ttaataattt ttttattttc aggaggaaaa tcatgcaaat gaatgaacag
     1321 tcatcacgac aaatggtgat tgccatctat ctcatttatt ccaactcaaa atgatagtac
     1381 tccttggctg ttccaagtcg aaattgttag tgattaagaa aacctacgag actatggttt
     1441 gatcgatgaa ggccagcagt ctcccagtga aaaagggcgt ttggctaata agatttattt
     1501 aggaaaattg gaacatgatt tcaccccagt cttaagttca gacggggcca gtctcaaaaa
     1561 cagaccagcc ccgtgttaaa ttcagcccct agtgagactg aaaagagtga aactgaaggt
     1621 agtgaaacta aagagagtaa tttagtcatt gaggacgagg aggaaagaaa ggagtgcact
     1681 agtgtgaaaa agactgaggg tcactttact cgtcaagttg atcatgtcac caaatatgac
     1741 aaagattata tttggagttt ggttcattcc caattacgtg aaggtggttt atcacaagct
     1801 gctagtgact tagtcatgag ctattttgaa gaacgctatg cttatgcgct ggaacacata
     1861 cggttcgcaa gaacagctga agctattgcg gaatatgtct ttaatggtgt cttatccgaa
     1921 tggaccaagc aactaaggtg acaagaagcg aagtgagtaa gatgttttgg tggctattat
     1981 taggtgtttg gggactaagg acaatttggt tgattattga agttatcact gcaccagaaa
     2041 tggaagatta tagttgagta aggacgttac ataagcagta aggtcctttt attttgtcag
     2101 aaaggaatga gagatatgca gtttttagat ttgtttgcag gaattggagg ctttcgattg
     2161 ggtttaatta atcagtgcca tgagtgtatt ggcttttgtg agattgataa gtttgcgagg
     2221 caatcttaca aagccatcta tgagaccgaa ggagaaatag aatttcatga cattagacaa
     2281 gtcacagacc aagactttag acaatttaga gggcaagtgg atatcatctg cggtggtttt
     2341 tcccttgtca agcattttca ctcgcaggca gacgactggg atttgagggc actaggagaa
     2401 ctctcttctt tgagattact cgagcgacca aacagataaa aatcataccc ataatcacat
     2461 ccaatcaacg ccattgaccg taattcagat aaaaaattga tatggaatta tgccttggaa
     2521 cgaaacctcc gtatgatttc agaccgtatt tcaaaaatga ctggagcaaa aattatcgag
     2581 aagcgttatt cctaccgtga ctatcaaaaa tataggcagt ctagtcataa atttgaattg
     2641 aaacaacgtc tttatttttt gatgcagcag tcaaagttct ttgatgattt tttagaaaaa
     2701 gcagagtaat tacatgttca tattgatttt agtcagaagc atagcagatt catgatgacg
     2761 gatcgagtaa tgaaaaaacc aattcgaggc cgtcaactca gtaaacgaga tttatatgat
     2821 gaagaatttt ttcgtacaca ttttgccaag atagaaattg aaagtcgatt agaatttttg
     2881 ttgaaccgtg ccaattcatt agaggagcta ctattaaaag caaaagaagt gaatctaacc
     2941 attgacttaa aacaaaaaat gtaactttta tcctagaaga agatactcaa aagataagtt
     3001 taggtcataa aaaaataagc gataagaaat tatatgatgt caattttttc aagattactt
     3061 taaaaaataa ggaagtcggt gtttcagatc gattagaaag tctacagaaa caatacatgc
     3121 ttttcaagaa gaacgagata aagagaaggt atccactgaa gagagtaagg aagtcttcaa
     3181 gaaatacaag gggcaacgag ataccatcca tgagtttgaa gttgaacttg tggaacatca
     3241 aattgagagg ttaattgctg aggacattta tatcaaggtg tcttttggtg taaagcagag
     3301 tggtcttatt ttcattccta actatcaatt ggatattagg aaagaagaaa atcataaaaa
     3361 atataaagtc tatattcgtg agaccgcaca attcttcatt tacaacaagg aggcgtctga
     3421 acttaatcgc tatatgcgag ggcatgagct catttaccag ttaaccaatg atagcaaaag
     3481 tattccaaaa agaagacgac aaaccattga tacacttaag aaaaagattg aagaaataag
     3541 tctcctcatt gagttagata cggagaataa gccttatcaa gatattaaag atgacattgt
     3601 taaagatatg gctcaattag atttgaccat tacagagttg caggaccata ttgctcatct
     3661 caataaggtt gcggaggtct tgcttaatct gaacaacaac gatatagaga accgccgttt
     3721 ggccagatat gactatgcca agatgaactt gactgcagct ataaaaatag aagaagttga
     3781 gaaagagatt gaaacttctc aaaatgaact taatatatcc atagatgagt atgaatatct
     3841 agtaagaagg ttggaaaagt ttggagagat cttgagtgat agcaaaatta tcgatacttc
     3901 tcgaaatgaa atacaatggg agtaattatg atataatttg ggtggtagca atttttatat
     3961 cagatattaa aatctagttg atgtttcgta aataactata ttaaagaaat gattcctgcc
     4021 gcttacattg agaatagttt atttgtaagt atttcattat ttaaaagggg taataatgta
     4081 taagatttta gccatagatg atgataaaga aattctgaag cttatgaaga ctgctttgga
     4141 gattgaaaat taccatgtta taacctgtca agagatagaa ttaccaatag tttttgatga
     4201 ttttaaagga tatgatttga tcttattgga tatcatgatg cctaatataa gtggaactga
     4261 gttttgttat aaaattcggg aagaagttca ttctccaatt atttttgtta gtgctttaga
     4321 tggcgataat gaaattgtcc aagctttaaa tataggggga gacgatttta ttgtgaaacc
     4381 atttagctta aaacaattcg tagctaaagt taactctcat ttgaagagag aagagagagc
     4441 aaagataaag aatgaggctg aggagagagt gaagcgaagt tttccaccta tagaaatcta
     4501 tctagaggaa cgtatgttat atattgataa acagccgtta ttcctgactt atagagagta
     4561 cgaaatttta gaattactgt cacgtcatcc gtataaagtt ttcacaaaag aagagatata
     4621 tgaacaagta tatagcgatg aagcttcagc attgtttcat tctatttcag aatatatcta
     4681 tcagattaga atgaaatttt caagttttgg aattaatcca ataaaaacta ttcgcgggat
     4741 tggttataaa tgggatgttt aaaaaatatt caataaaaaa tcgtgtttgg cgcgccgtcg
     4801 ttgaaattgt ctttggagtt tgtatcactg ttttaatgat tgcgataata tcgctttctt
     4861 tttcaaagtt aaatatagtg acatctcata atgt
//
LOCUS       DAUNLR010000079         4564 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUNLR010000079 DAUNLR010000000
VERSION     DAUNLR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4564
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.079"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            185..634
                     /locus_tag="VLL59_001663"
     CDS             185..634
                     /locus_tag="VLL59_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HER6509767.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            810..1094
                     /locus_tag="VLL59_001664"
     CDS             810..1094
                     /locus_tag="VLL59_001664"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HER6509768.1"
                     /translation="MRLEEIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQRLTGGDIND"
     gene            1087..2349
                     /locus_tag="VLL59_001665"
     CDS             1087..2349
                     /locus_tag="VLL59_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HER6509769.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGATVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHV
                     GRYSGLGTHLLAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            2464..2811
                     /gene="rplS"
                     /locus_tag="VLL59_001666"
     CDS             2464..2811
                     /gene="rplS"
                     /locus_tag="VLL59_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HER6509770.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3058..3129
                     /locus_tag="VLL59_001667"
     tRNA            3058..3129
                     /locus_tag="VLL59_001667"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3091..3093,aa:Arg,seq:cct)
     gene            complement(3174..4250)
                     /locus_tag="VLL59_001668"
     CDS             complement(3174..4250)
                     /locus_tag="VLL59_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HER6509771.1"
                     /translation="MWIEELLNGKFKFIERYTDPLTGKYKKVSVTLDKNSNQAKNKAS
                     IIIKEKIEDRLAIRDHSEMTYGELKREYLNQWIPTVKDSTKRGYLVSDGHIATVLPDD
                     TIISKLTKRDIRQFIDNLLKNHSYHVTHKCRKRLHAILSYAIQMDYLTSNPTDNVLVP
                     KPKEEYMPEKVLYLTSNEVYDLCGRMIANNEQTLADVVLFMFLTGMRYGELACLTYDK
                     IDFENKEILINATYDFYTKEITTTKTKKSTRKISVSDNILEIINRQNKVSEFIFPNSK
                     GLPILNAYINKRLKIYGNYHTHLFRHSHISFLAEKGIPLKAIMDRVGHSDPNTTLSIY
                     SHTTVNMKALINNQTAPFMPLKII"
BASE COUNT         1310 a          790 c          923 g         1541 t
ORIGIN      
        1 atctaggaag aaaagaggtt agttatcagt tatgatacta tcaaagctag tcttgcaaat
       61 gcaagtgaaa aaatagtttt taagtgtttt aagcaatcat atcaaccttc tcgttaaaca
      121 attagtgctt ttcctaaaaa agtgtgctaa aataaacata gtttagtaat tttgggagga
      181 atttatggca ttagcaaaaa tcgtttatgc cagcatgacg ggaaatactg aagaaatcgc
      241 tgatatcgtt gcaaataaat tgcaagaatt gggccatgat gttgacattg atgagtgcac
      301 aacagttgac gcttcagagt ttgagaatgc tgatatcgct gtcgttgcga cttatactta
      361 tggtgatggt gacttaccag atgaaatcgt tgatttttac gaagatttac aagatttaga
      421 tttagaaggt aaaatctatg gcgttgtcgg ctctggtgac actttttatg actatttttg
      481 caaatctgtt gatgactttt cagagcaatt tgcgcttact ggtgccatca aaggtgcaga
      541 gcctgtcaaa gtagacttgg cagcagaaga tgaagacatc gatcgtttag aggcctttgc
      601 agagcaactc tcacaggctg ttaataatct ataaaactat ttagtaaaaa tgtcagggac
      661 ttccttggca tttttagatt tttaatctaa aataaaggga atgtcacttc agggtaggaa
      721 ttgaaaaaaa caatcagctt caccttgctt ctgatcctct tattaactat aataaaaaga
      781 taatctaata catctagaaa aggaaagtta tgcgtttaga agagatacga caagaaatca
      841 atggtattga tcaccacttg gttgccttat tagaaaagcg gatggcactt gtagagcaag
      901 taacagctta taaactagcc aatcacttgc ctgtcttaga tcaggcgagg gaaaatcaga
      961 tcctagatag ggtttcttat ctcgttaaag accaagcatt tgagccagct atccatgaga
     1021 cgtttaaaac cattatgtct ctttcacggc agtatcaaac gcaacgctta acaggtggtg
     1081 acattaatga ttaaatcaat tgcaacactg cctaaaccct ccttaaaaga agcgttagga
     1141 ctaataggct tggcgcttcc cataggggcc acggttggag tggttgatgt gatttttggt
     1201 aaagggcttt tgtttctttc cgaatatcgc gatcaccacc tgttcttgct tcttcctttt
     1261 cttgccctag caggtcttgt tatcgttttt ctttacgata agttaggcaa agaggttcgt
     1321 caagggatgg gattggtttt tcaggtaggg catggtcaaa aagatcagat tcctcctatt
     1381 ctcattcctc ttattttgtt ctcgacttgg gtaacccact tatttggagc gagtgcgggt
     1441 cgagaagggg tagccgttca aataggagct accatctctc attattgtca gagatttgtg
     1501 actagtcaag aagccgcacg acaccttttg attatgggga tggcagccgg ttttgcagga
     1561 ctttttcaaa cgccgattgc tgctgtcgta tttgcccttg aggttttgtt ggtaggaacg
     1621 cttcgctact gcgctttatt gccttcctta gttgctgctt gcgtggcttc ttggacctct
     1681 cattctttgg gattagagaa atttacgatt gttcttgaag aaacattgac cataactccc
     1741 ttaaccttag ttaaattaat tgggttaggt cttatttttg gtctggtggg aaatagtttt
     1801 gcctgtttac ttggctggtt taaaccttac ctgagtcaaa agctaccaaa tccttatctc
     1861 cggattgctt tcattggtgt tttgttatct atctgtttga tgattggtca cgttggaaga
     1921 tatagtggtc tagggactca tttgcttgcg gcagcttttt ctggccaaac tatcctaact
     1981 tacgactggc ttttaaaaat gatcgtgacg gtgattagct tatctgcagg ctttcaaggt
     2041 ggtgaagtga cgcctctatt tgctattgga gcttctttag gcatcgtttt ggccccttac
     2101 ttaggtcttc ctgtactgtt ggttgctgca cttggttatg tcacggtatt tggaagtgca
     2161 acaaatacct tttgggcccc tatctttatt gggatagagg tctttggtcc agagaatgcc
     2221 ctagcatatt ttgtcacctc ggctgcagcc tatatggtta gtcacagaca ttccatttac
     2281 agttatcaaa aagtagtcat gatcaattta aaagacatga cggtaaatca gatggattta
     2341 aaaaaatagc tttacaataa agaagctttt tgttagaata aatctcgtgt gtaatggaca
     2401 cacgaaaatt acggctaatc cgctaagaca agtacttaag attagtaaga taggagaata
     2461 aaaatgaatc cattaatcca aagtttgaca gaaggtcaac ttcgctctga tatccctaac
     2521 ttccgtcctg gtgacactgt tcgcgttcac gcaaaagttg tcgaaggaac tcgcgaacgt
     2581 atccagatct ttgaaggtgt tgttatttca cgtaaaggtc aagggatctc agaaatgtac
     2641 actgttcgta aaatctcagg tggtatcggg gtagagcgta cattcccaat ccacacacca
     2701 cgtgttgaca aaatcgaagt tatccgccac ggtaaagtcc gtcgtgcgaa actttactac
     2761 ttgcgtgcat tacaaggtaa agcagctcgt atcaaagaaa ttcgtcgtta gtttgaaccg
     2821 aaacgtaacg taatagaata aaaagactag agtctctagt ctttttatgt cgtcgtgaca
     2881 atgtgacaat tggtgattaa cgctatgctc gtaggacact ttgaaagttc cttagcagtt
     2941 ataattagta tattgtaata acaaaatgaa gcaaaataaa ctttcagtta tctgatattt
     3001 catcttgcat taccttattt tctaggttaa aatagaagac aaggtgaata taagatagac
     3061 cccttagttc aatggatata acaactccct cctaaggagt agttgctggt tcgattccgg
     3121 caggggtcat tattgttaac ttaaaaagcc tttatatcag gcttttttta ttactaaatt
     3181 atttttaggg gcataaaagg ggcagtttga ttattaatca atgctttcat atttacagtt
     3241 gtatgactgt aaattgataa tgttgtgttg gggtctgaat ggccaactct gtccataatc
     3301 gcttttagtg gtattccttt ttcggctaaa aacgaaatgt gtgagtgtct gaataagtga
     3361 gtatgatagt taccataaat tttcaggcgc ttattgatgt atgcgtttaa aattggtaaa
     3421 ccttttgaat ttggaaaaat aaattcactc actttatttt gtcgattgat gatttctaaa
     3481 atgttatcag atacggaaat tttgcgagtt gattttttag tcttagtagt cgtaatttct
     3541 ttagtgtaaa aatcgtaagt tgcgttaatc agaatttctt tattttcaaa atcaatctta
     3601 tcataagtca gacaagcaag ctcaccatat ctcatacccg ttaaaaacat gaataaaacg
     3661 acatctgcga gcgtttgttc attgttggct atcattctac cacagaggtc ataaacttca
     3721 ttagatgtta aataaagtac cttttcaggc atatattcct cttttggctt aggtactaaa
     3781 acattatctg tcggattgct tgttaaatag tccatttgga ttgcgtaaga caaaatagcg
     3841 tgtaatcttt ttctgcattt atgtgtaaca tggtacgaat ggtttttcaa taagttgtca
     3901 ataaattgtc taatgtcgcg tttagtcaac ttgctgataa ttgtatcatc tggcaacacg
     3961 gttgcgatat gaccgtctga gactaaataa ccacgcttgg tggagtcttt gaccgttgga
     4021 atccattgat ttaaatattc gcgttttaat tcaccatagg tcatctcaga atgatcgcga
     4081 atagcgagtc tatcttcaat cttttctttg ataataatac ttgctttatt cttggcttga
     4141 ttactattct tatcaagtgt cacagatact tttttatatt ttccggttaa tgggtctgta
     4201 taacgttcga taaatttaaa ttttccattt aataattctt caatccacat ttgttttata
     4261 cctcaatttc tgttaaaatg ggtataagaa aacgagccat ttaatgcttg tttcttatac
     4321 ggtttggcct cacactcaac gtttggcgat ggcgagtgtg gggctttttt atttgtctaa
     4381 aagtaagtag ccgtctatat aaattagagg gacactattc tcggaaccac ttgttgtcgt
     4441 atattcataa gataataaat atcttccatt gatagtgata ttatcagttt ctaaaagctt
     4501 agtttctagt cgcttggttt cgataaacaa catatacaag tccccattag gggtgtttgc
     4561 taga
//
LOCUS       DAUNLR010000080         4382 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUNLR010000080 DAUNLR010000000
VERSION     DAUNLR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4382
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.080"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(215..578)
                     /locus_tag="VLL59_001669"
                     /pseudo
     CDS             complement(215..578)
                     /locus_tag="VLL59_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(999..1532)
                     /locus_tag="VLL59_001670"
     CDS             complement(999..1532)
                     /locus_tag="VLL59_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HER6509772.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1612..2388)
                     /gene="recX"
                     /locus_tag="VLL59_001671"
     CDS             complement(1612..2388)
                     /gene="recX"
                     /locus_tag="VLL59_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HER6509773.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQNNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2503..3858
                     /gene="rlmD"
                     /locus_tag="VLL59_001672"
     CDS             2503..3858
                     /gene="rlmD"
                     /locus_tag="VLL59_001672"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HER6509774.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
BASE COUNT         1314 a          709 c          915 g         1444 t
ORIGIN      
        1 tataacaaat ttaagctttt tattgtttct ttttaattgc agattgaggt ttaaaagaca
       61 cgttacaatg ttttcaagtc atgtgttgtt gtaggttgta tgcacatatt acaaatccca
      121 ttataaaaga aattgtttaa ttaatggata gtaatggatg gtatggagat cttaatgtgg
      181 ttttaatggt aattttagca gttatagtaa gacaaaaggt gacttggaaa agcttatgca
      241 gacgattctt aactcccaca atatcttctg tcagatttta ttagacttct tctcagtgtc
      301 aattttgtct gttttacgaa cgtgcaggct attcaattgc ttcttagctt ctaaaggatt
      361 aaaccgagta taagcgtagc cattatctgc gaaaaaacct gaagacgacg agaatagaca
      421 ttaatcgttt taaggataat ctcagggtta tggacggttt tcaagtttcc aagaagacga
      481 ttgaggccga tggtatcgtt ttgtcttgaa tgattcctta ttttagtggt ttcattttca
      541 atacacgacg tcaagcgtcc tacatacttt gataaaattc tacctaaaag aggtgtcttg
      601 tcagttttgg ttacaacatc aagtgccaaa agactttgcg acttaacaag acacttctac
      661 tttaacgcaa agaaaaagta gtgagtactc tctttcgtcg gagatttcct cgctactaaa
      721 cttagtattt tttgatactt tccttaggta gtgcttaagg cagcgacttc ctttggaatt
      781 ccatgcctta tttttgagat cctaggctca aaaataccaa gtggcgtcaa cactaacatt
      841 gacgccactt ttaccacaac gaaaaacatc tgttttggct cactccacac gcagaaatag
      901 gaaattggat gtcaaatcag cagagctgtt catgcttttt gagcctaaaa ctgagtttgt
      961 ctgcgttctg agcactcctt gggagtgctg gacaactctt aacgattctt cagttcaaga
     1021 taacgtttgt accaaatagt gatataggcc ttggaaaatg gtcctttttc atgattaatc
     1081 caatcaacca atattttgac attttctttt aggataaagt ccatatcggc tgaatactgc
     1141 atctcttttt tatgaatctc gtattcatca acatcaagta atctcttttc accatccgca
     1201 aagactttga catctaaatc gtaatcaatg tatttgaggg cctcagtgtc catcatgtat
     1261 ggactagcta agttacagta ataagagacg ccattatctc gaatcatggc tataatgtta
     1321 aaccagtatt ttttatgaaa gtaaacgatt gcaggttcgc gggtcaccca tcgtctaccg
     1381 tcactttctg tgacaagagt gtgatcatta actccaatga gggcattttc agttgttttt
     1441 agtaccatag tatcgcgcca agtacggtgc aaactaccat catgcttata actttgaatt
     1501 gtaataaagt cgccttcttt aggtaatttc atgccttacc aactttctac aattaaactt
     1561 atcctctata gtctatcata aatgtgtgaa aaaatcactt cttttgtcag tctataaata
     1621 atttcttaac ttgcaattaa tatcgtcgct gttgtagcct tttcggtaga gagcctgata
     1681 gagcttttgc tttaaggtat aaccatcata tttgcgactg agtttacgat attgtttgtc
     1741 taattctttg tcaagaagat cttctatttc ttgattattt tggtcaaaat taaggtgatt
     1801 gaggctatgt ttagctagat cgtatgaaaa gcctttggtc agtaatgctt gggtgatttt
     1861 atctttcaag gcttttggtg gcaatttttc ttgatatttg tcaaagagtt tttggcttac
     1921 tttttgagcg agttggctaa agtcagtttg agataagata ggatcaatgt cgtgacttgc
     1981 aatgcctttt tgtaataatt tttgttttaa gacttgggga cctttatcac catttaactg
     2041 attttggcga atgtaggtat cagccaattt ggtgtcgtct atccattgtt cttcttggag
     2101 ttgagtgatg atgtcagcaa taatatgttc ttcaatctca tgcttgcgca ggtaatcagc
     2161 aacttgcttg ttgctgcgtt gttgaaagga aagaaaataa agggctaaat ttttgccgta
     2221 ggacagttgg gcaaaatgtt tcatgtcttc aagctgatca ttgtcaagga ctttatcttt
     2281 actcaacata aaccgaacaa tagtatcttc tgttacataa agggattcgt cattatccaa
     2341 ttcgataagg tagaggcgtt ttttcttttc aattttagtg attttcatac tttgattata
     2401 tcaaaaatgg taaaatagaa gacgaaaata ctgctaaaaa tgtgttgctt gtgaatgctt
     2461 ttggtggtga gattaggata ttagaggaag taaggggaag agatggtcgt aaaggttaaa
     2521 cagaaaattc ctttaaaaat taagcgaatg ggaattaacg gtgaggggat tggtttttat
     2581 cagaaaactt tggtatttgt ccctggtgct ttaaagggag aagatatttt ttgccaaatc
     2641 acggcggtta aacggaattt tgcagaggcc aaactgttaa cggtaaacaa ggcttctaag
     2701 aatcgtgtca aaccagcttg ttctgtttat gaaacttgtg gtggttgcca aatcatgcat
     2761 ctagcctatc ctaaacagct agatttcaaa gatgatgtga ttagacaggc ccttaaaaag
     2821 ttcaaaccaa ctggctatga acaatttgag attagaccga ctttaggaat gaaaaagcca
     2881 gatcactatc gggccaaatt gcagtttcag ctgcggtcat ttggcgggac ggtcaaggct
     2941 ggtttatttt cccagggaag tcatcgcttg gttcctattg acaattgctt ggtacaggat
     3001 caactaacgc aagatattat caataagatt acgcagttag tggacaagta caagttgccc
     3061 atttacaatg agcgcaagat tgctgggatt cggacgataa tggttcgtaa ggcacaggct
     3121 agtgatcagg tacagattat tgttgtgagt agcaaagaag ttaggttagc gaatttcatt
     3181 ggcgaattga ctaaggcatt tcctcaggtt aaaacggttg ccttgaatag taatcgttct
     3241 aaatcgagtg agatttatgg ggacgaaacg gaaattctat ggggacaaga ggcgattcat
     3301 gaagaagttt tagactatgg atttgcgtta tcaccgagag ctttttacca acttaatcca
     3361 cagcagacag aagttttgta tggtgaggtg gtgaaggcct tggatgtagg gagcaaagat
     3421 catattattg atgcctattg tggggttggc tcgattggct ttgcttttgc agggaaggtc
     3481 aagtctgtgc ggggaatgga tattatccca gaagcgattg aagatgcaca aaaaaatgcc
     3541 aaagccatgg gctttgacaa cgcttactat gaggcaggga aggcagagga tattattcct
     3601 aaatggtata aacaaggtta ccgcgcggat gccatcattg tggacccacc aagaactggt
     3661 ttagatgata aattattaaa aacgattctt cattaccagc ctaaacagat ggtttatgtg
     3721 tcttgtaata cctccacttt ggcccgcgac ttggtgcagc taacaaaggt ttacgatgtt
     3781 cactatatcc aaagtgtaga catgttcccc catacagcta ggaccgaggc tgtcgtgaag
     3841 ttacaaaaac gtgtatgatt gagtggcaat aacaactcaa gttttataag ctcaggtaat
     3901 gggtttgagc aatagcttga catagtaggg atgtcaaaaa cggtttacta agcatagtca
     3961 tattattgat aactctatgt ttattttaga aacattcatg gttaaaaaag tttgttagtt
     4021 tgtcactaag tagggtttat ttgaagagca agtacacaca gacaatatta gggtaattga
     4081 ttgttgaaaa atagctgttt tttgctataa attagaaaac tgagtggtca ggaggttaca
     4141 ttaccagaag ttattttagt atgctaatat gaacgatgat atagaggatt tatcctgatt
     4201 taatctttta agctgtaaga aacctttgca aaaactgtag gctgtgtgag tctttatgtg
     4261 ttagatatta aagataaatg caacactttt ttataatgag atcaacaact gataaatctg
     4321 agttgataac cagtaaaatg atcggaatgt agaaaagtta cttaatcaag cttttcgtaa
     4381 tt
//
LOCUS       DAUNLR010000081         4283 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUNLR010000081 DAUNLR010000000
VERSION     DAUNLR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4283
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.081"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            65..607
                     /gene="hpt"
                     /locus_tag="VLL59_001673"
     CDS             65..607
                     /gene="hpt"
                     /locus_tag="VLL59_001673"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HER6509775.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            629..2608
                     /gene="ftsH"
                     /locus_tag="VLL59_001674"
     CDS             629..2608
                     /gene="ftsH"
                     /locus_tag="VLL59_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HER6509776.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     SYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            2935..>4283
                     /locus_tag="VLL59_001675"
     CDS             2935..>4283
                     /locus_tag="VLL59_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HER6509777.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTL"
BASE COUNT         1409 a          628 c          844 g         1402 t
ORIGIN      
        1 gcttgtaaac atgatataat gttggctaaa ctgtatattg ataaattaga aaaagggtga
       61 caacatgctc gagcaagata ttcaaaaaat tctttactct gaaaatgata ttattcggaa
      121 aactaaaaaa ttaggagaac aattaacaaa agattatcaa gaaaaaaatc cgcttatgat
      181 tggtgtatta aaaggatcag ttccttttat ggcagaacta atgaaacaca tcgatactca
      241 tgttgaaatt gattttatgg tagtatcaag ttatcatggc ggtacatcta gcagtggtga
      301 agttaaaatt ttaaaagatg tagataccaa tattgaagga agagatatca taattgttga
      361 agatattatt gacaccggtc gcaccttaaa atatttacga gatatgttta agtaccgtaa
      421 agctaatact atcaaaattg caacactgtt tgataaacct gaaggtcgtg ttgttaaaat
      481 tgaagcagat tatgtttgtt acaatattcc aaatgaattt atcgtaggct ttggtttaga
      541 ttacgcagaa aattatcgca atcttcctta cgtaggtgta ttaaaagaag aagtctattc
      601 aaaatagaaa aaggtcaatg tttactgtat gaaaaataat aaaaataatg gttttgttaa
      661 aaattctttt atatatatat tgatgattat tgttgtcatc acaggatttc aattttatct
      721 taagggaacc agcacacaaa gccaacagat tagttattcc aaattaatta aacatcttaa
      781 ggctggagat ataaaatctt taagttatca gcctagcggt agtattattg aagttaaagg
      841 gaaatatgag aaacctcaaa aagtgacagt taattcagga ctatcatttt taggtggaag
      901 agcttcaaca caggtaacag agttctcatc tttagtatta cctagtgata ccatcttgaa
      961 agaaatgaca gcagcagctg ataaaaatgg aacagagctt acagttaagc aggaaagttc
     1021 aagtggtact tggattacct tcttaatgag ctttttacct attgttattt ttgctgcttt
     1081 catgatgatg atgatgaatc aaggtggtgg aggagctcgt ggtgctatga gtttcggcaa
     1141 aaataaggca aaatctcaat caaaaggcga tgttaaagtg agatttacag acgttgctgg
     1201 tgccgaagaa gaaaaacaag aattagtaga agttgttgat tttttgaaaa atcctaaaaa
     1261 atataaatca ctaggagcac ggatcccagc gggagttctt ctagaggggc ctccaggtac
     1321 tggtaaaaca ttactagcta aagctgtagc aggtgaagct ggagtgccat ttttcagtat
     1381 ttcaggttca gattttgtcg aaatgtttgt cggtgtaggt gctagtcgtg ttcgttcttt
     1441 atttgaggat gctaaaaaag ctgagcgtgc aatcatcttt atcgatgaaa ttgacgctgt
     1501 aggtcgtcgt cgtggtgctg gcatgggagg cggtaacgat gaacgagaac agacccttaa
     1561 ccaattactc attgaaatgg atggttttga gggtaatgag aacattatcg ttattgctgc
     1621 aactaaccgt agtgatgttt tagatccagc tttactaaga ccaggtcgtt ttgatcgtaa
     1681 ggttttagtt ggtcgccctg atgttaaagg acgtgaagcc attttacgtg ttcatgctaa
     1741 aaataaacca cttgcaaatg acgttaattt gaaagtagta gcccaacaga ctccaggttt
     1801 tgtaggtgct gatcttgaaa atgttttaaa tgaagctgcg ttggttgctg ctcgcagaaa
     1861 taaaattaaa attgacgcta gtgatattga tgaagctgaa gatcgtgtta ttgctggacc
     1921 atcaaagaaa gatcgcacta tttcgcaaaa agagcgagaa atggttgctt atcacgaagc
     1981 tggtcatact attgttggtt tagttttatc taatgcgcgt gtagttcaca aggtaactat
     2041 tgtacctcgt ggacgagcag gtggttatat gatcgctctt ccaaaagaag atcaaatgct
     2101 tctttctaaa gaagatctga aagagcaatt agcaggattg atgggtggtc gtgttgctga
     2161 agaaattgtt tttaatgctc aaacatcagg tgcgtcaaat gactttgagc aagctactca
     2221 gatagcaagg gccatggtta cggaatatgg tatgagtgaa aagcttggac cagttcaata
     2281 tgaaggtaac catgcgatga tgccaggaca gatctctcct gaaaaatctt actctgccca
     2341 aacagctcaa atgattgatg atgaggttcg tgaactctta aatcaagctc gtaatcaagc
     2401 agctgatatc atcaatgaga atcgagatac tcataaattg attgctgaag ctcttctcaa
     2461 atatgaaact ctagacgctg cacaaattaa atcaatttat gaaactggta aaatgccagt
     2521 tgatttagaa actgatgata atgaagctca tgcgttatct tatgacgaaa ttaaaaataa
     2581 aatgacagaa tctgaatctg cagaatgata taaaaaagct gaacttatag attaagttca
     2641 gcttttttat caacacaata tccttgtaaa cgttatgaat tgtaataggt gcctaattgc
     2701 tagaaatgag aagatgacat actttttttt ctttattact taaagtgaga aagactttgg
     2761 tatttaaaac tagaaaattg ttaaagccat ttgaaaaaat ctattagtgt tttcttagaa
     2821 taatagaaga acagaagata gcaaaagttt cagtcaacca ataagatgaa atttacaatc
     2881 attactaact atgatacact tagtagaaaa tcatttacta tagaaggtga taacatgact
     2941 atttttcgta aaaaaaagaa atattccaat aaaacagaaa tgcaaaggca cttcaaagtt
     3001 attgatttag tttttttagg cctaggttca atggttggaa caggtatctt tacagttact
     3061 ggcataggcg ctgctaagta tgcaggtcct gctttaacaa tatcgattat catttccgcg
     3121 attgctattg gaattttagc cttattttat gcagaatttg cgtctcgtat gccttctaac
     3181 ggtggtgctt atagttatgt ttatgcaacc ttgggagagt ttccagcatg gcttgttggc
     3241 tggtatatta ttatggaatt tttaacagct atatctagtg ttgctgttgg ctggggaagt
     3301 tatttaaaag gattacttgc caattataat atagtattac caaacgcttt aaatggcacg
     3361 ttcaatctta agaatggaac ttacatagat attcttcctg ttttagtgat gtttttcgtg
     3421 acagggattg tcctaatgaa ttcgaaatta gccctgagat tcaatagttt tttagttatt
     3481 ttaaaatttt cagcactggc tttatttatc tttgtaggca ttttttttat tgatcacaat
     3541 aattggtctc attttgctcc atatggtgta ggacaaatta ctggaggtaa aacaggtatc
     3601 tttgctggtg cttctgttat gttctttgca tttttaggat ttgaatctat ttcaatggca
     3661 gttgatgaag tgaaagaacc acaaaaaaca attcctaaag gtatcatttt atctttgatt
     3721 attgtaacag cactctatat agttgtcacc actattttaa cgggaattgt acactacact
     3781 aaattaaatg ttccagacgc ggtggctttt gctttaagaa atattagact ttattgggca
     3841 gctgactatg tgtcgatagt tgctattttg actcttatta cggtatgtat ttctatgacc
     3901 tatgcattag ctagaacaat ttacagtatt agtagagatg gtttattacc taaatcactt
     3961 tatactctca ctaaaaaaaa taaagtgcct caaaatgcta ctcttgtcac tggactactt
     4021 gctatgattt gtgcgggaat atttccttta tcgagtctag cagagtttgt taatatttgt
     4081 actttagcat atttaattat tctgtcgggt gcaattatta aactcagaag aatagaagga
     4141 gaaccaaaag caaatgaatt taaaactcct ctagtaccat tcctaccaat gttggcaatt
     4201 atcatttgtc tatcatttat gagccaatat aaagctttta cttggattgc ttttgctatt
     4261 gccacaatta ttgggacatt aat
//
LOCUS       DAUNLR010000082         4027 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUNLR010000082 DAUNLR010000000
VERSION     DAUNLR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4027
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.082"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            1..972
                     /locus_tag="VLL59_001676"
                     /pseudo
     CDS             1..972
                     /locus_tag="VLL59_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1272..2144)
                     /locus_tag="VLL59_001677"
     CDS             complement(1272..2144)
                     /locus_tag="VLL59_001677"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HER6509778.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYISSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            2368..3678
                     /locus_tag="VLL59_001678"
     CDS             2368..3678
                     /locus_tag="VLL59_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HER6509779.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            3756..3893
                     /locus_tag="VLL59_001679"
                     /pseudo
     CDS             3756..3893
                     /locus_tag="VLL59_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304910.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1211 a          892 c          741 g         1183 t
ORIGIN      
        1 tttggaagag atgacagagg ttgaacgtct tcagaaggaa ttagaatacc ctagagcgga
       61 gaatgctgtg ctaaaaaagc tgagagaata ccgcttgaga gacgaagcaa aactcaaaga
      121 gcaacagaaa tcattcaagc attaaggaat ccatttccct tagagatgct acttgaaatc
      181 cttgatttat cacgctccac ctattactat caagtgaagc gactagctca aggagataag
      241 gatatagaac taaagcatgt gattcgagag atttatgatg agcataaagg taattacggt
      301 tatcgtcgta ttcatatgga gttgcgtaac cgaggatttg tggtcaatca taagaaagtt
      361 caacgtctca tgaaagtcat gggcctagca gcccgcattc gtcggaagcg caagtattct
      421 tcttacaaag gagaggttgg taagaaggct gataatctga ttaaacgtca cttcgaaggc
      481 tctaaacctt acgaaaaatg ttacactgat gtgacggagt tggccttacc tgaaggaaaa
      541 ctctacttat tacctgttct tgacggctat aacagtgaga ttattgattt cactctgtct
      601 cggtctccta acttgaaaca ggttcaaacc atgcttgaga agacttttcc agcggattca
      661 tacagcggaa ctattcttca tagtgaccag gggtggcaat accaacacca gtcctaccat
      721 gattttttag agtctaaagg tattttgcca tccacgtccc gcaaagggaa tagcccggat
      781 aacggcatga tggaatcctt ctttggcatt ctcaaatctg aaatgtttta tggactcgag
      841 acaacttatc aatcacttga caagcttgaa gaagctatta cagattacat tttttactac
      901 aacaacaaac gaattaaagc aaaactaaaa ggatttagtc ctgtccaata cagaactaaa
      961 tcctttcaat aattatttgt ccaacttttt ggggtcagta cactcctagt taacgacttt
     1021 gattgatttt attatgatga atcgtgattt ctgaaaacaa acttttcttc atggatttgg
     1081 cgtggaactt ttacaataaa aacactaacc tctccctatc gttttttcag gtgaatgctt
     1141 ggaattggta taataagcgg acacgaatca ggtgaaaaca gggaaagtat ttgaagaggc
     1201 gtttaaacta tctgacataa aactcgttct agaggaaaga cattctttaa aaagttagtt
     1261 tattttgcaa cttagacatc aaggtaggtt aaacccttca tggaaaaatc gagactctta
     1321 gcactatggg ttaaactacc actggagatg taatcaatcg ctaaaccacg aaaacggcta
     1381 atagtggtca tatcaatatt tccagaacat tcaatccgag aacgtcctgc aattagagta
     1441 atggcctgtt caatctgttc caatgacata ttatccaaca tgataatatc aacacccgcc
     1501 gccgcagctt cttcggcagc agcaaggctt tccacttcca cctcgaccat tttcacaaaa
     1561 ggggcatagg cacgcgcttg agcaatcgcc ttttgaacac tacctactgc cgcaatgtga
     1621 ttgtctttta gcatgatagc atctgataaa ttaaagcgat gattatagcc accgccaact
     1681 ctcacggcat atttctcaaa aagacgtaaa ttaggagtgg tttttcgagt atcaaatacc
     1741 ttaatgcgat catcgcctaa ggcttctaca taagcagctg tcatcgaagc aatccctgat
     1801 aaatgttgta aaaaattcaa ggcaacgcgt tcacatgtta agaggcttct caccgagcct
     1861 atgatttcta aaaccaaatc gccactagtc aaacgatccc catccttaaa ttgatgagga
     1921 ttctggaagg tcacctcggc atcaaatagg gtaaaaaccc tttgaaaaac ggttagcccc
     1981 gctaaaacac cagcttcctt ggcaaaaagc gacaccttgg cttggccatg atgatcaaaa
     2041 atggcattgg tactgtaatc ttcggaatga acatcttctc gcaaggctgc tttcaatgta
     2101 tcatctattt gaaaaggggt taaatcagtt gaaatgattg acatcactaa gtcctctatt
     2161 tttaatatca cttgtaagca ctagaggcaa ttgctattaa cttccgtagg aaatcacaaa
     2221 cctgaatacc tcattttaaa tcccaacaag tgtcaagaca attgtaattt ttttgtgtat
     2281 aatagtcaag taccaatagg aaacaggtgg tcttttgagc gccaaaattg ccaacctatt
     2341 ttcatattct aactaaagga caattcaatg attcatttaa taataattag cgccattgct
     2401 ctagccattg gaattggtta ccgcaccaaa atcaatattg gcctgctggc tattgctttt
     2461 tcttacctca tcgcaaccac tctcatggga ttaagcccca aagaacttct tcatttttgg
     2521 ccaacctcac tcttttttac catttttagc gtctctctct tttataacgt tgcaacaact
     2581 aacggcactc ttgatgtttt ggctcaacac attctctacc gcacacgcac ccaccctaac
     2641 gccctctaca tgattttata cctgatagca acccttttgt ctgctttagg tgctggattt
     2701 ttcactacta tggccgtttg ctgtcctcta gcgattaccc tctgtcaaaa agcggacaaa
     2761 caccctttga ttggagctca agccgtcaat tggggagctt caggaggggc taatttgata
     2821 accagtggct caggcattgt ctttcaaggc ctgtttaagc aaatgggatg ggaagagcaa
     2881 gctttttcac ttggcaatca tatctttatc gtcagcatta tctacccact catcgtcttg
     2941 cttttattat cttgttacat ccgctacagt aagggaagaa caaactcatc cttgactatt
     3001 gaccaaccac cagtcctcag caaggtccaa agacaaacca ccttgctcat gatcagcagc
     3061 atggttttgg tttggctttt tcccttgttg catctcattt tcccaaacat cgcatggata
     3121 gctacttatc gacaaacatt tgatattggc tttgtctcaa tactcatggt ctgcctcgcc
     3181 ttaaggctca aattagggaa gcaagaagcc attttggcta aggttccctg ggctataatt
     3241 atcatgctct gcggcatgag cttactaatg tctctagcgg tcaagtcagg tttagttaca
     3301 ctgatagggc acctcataac aacaaccatt cctcatttct ggttacctct gttcttttgt
     3361 gtgatagccg gagtgatgtc actctttagt tccaccctat ccgttgtagc cccaactctc
     3421 tttcccatca ttgctaccat cagtgctcaa agtcctcaca ttgatattcg cttactcaca
     3481 acagccacta ttattggcgc tctatctact aatatctctc ctttttcatc agctggttct
     3541 ctcattcaac tctcccttcc ccatatagag gaacgcagtc ttgctttcaa aaaacaaatt
     3601 cttctgggtg tgcccatcag cttaagtttg gcactcttga ccatctggat tctcatgctg
     3661 ctagcttcct taagttagat ttattgtcta acttaaggct ggacttggta tactaaagta
     3721 gacacaaaat taagtgaaaa cgaggaatag tcattatgcc aagaaaaacc tttgataaag
     3781 ccttcaaact ctctgctgta aaactcatcc ttgaggaaga gcagcctgta aaaatggtta
     3841 gttcaacttt agaaattcat cccaatagtc tttatcaatg gattcaagaa tatgaaaaat
     3901 atggagaaag tgcgttccca ggacatggga gcgcacttcg tcatgctcaa tttgagacaa
     3961 aaaaacttga aaaagagcac aaactgctac aggaggaatt agctcttcta aaaaagttcc
     4021 aggtctt
//
LOCUS       DAUNLR010000083         3620 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUNLR010000083 DAUNLR010000000
VERSION     DAUNLR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3620
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.083"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            624..872
                     /locus_tag="VLL59_001680"
     CDS             624..872
                     /locus_tag="VLL59_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HER6509780.1"
                     /translation="MENIVPVSDMRYYNQTLSDVSVGSQVILTRNGKAEYAVVDIEEW
                     RRTKATLRLFEELQKGYRSLANEKTYTPDELAERLGVD"
     gene            872..1189
                     /locus_tag="VLL59_001681"
     CDS             872..1189
                     /locus_tag="VLL59_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HER6509781.1"
                     /translation="MSYKVITSSETVRDIEEAVFYKEGLGVYPENVVKFKKAVVSTIR
                     KLVDSPKIGANLSARIDEETEIKYSVIDDYILFYEIEADTVKVLRLLPAKTNWVNTIL
                     KYL"
     gene            1503..2444
                     /locus_tag="VLL59_001682"
     CDS             1503..2444
                     /locus_tag="VLL59_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HER6509782.1"
                     /translation="MVNELNQEEVLRDKNSKGKDRDWRGRKIMSLKLADVFENLGYKK
                     SMIERVQSCGEVLNFIRHSDGSLKLYQAYFCKNKLCPMCNWRRSMKYSYQTSRIVDEA
                     IKRESKGRFLFLTLTVKNVPGSDLNKTLSSLTQSFDRLFRRAKVKKNLIGYLRSVEVT
                     HNELTNEYHPHIHVLLMLKISYFKGGNYITQKEWGEMWSQSLKVDYVPMIDIRAVKEK
                     GKGLKGAILETAKYPTKPIKLEMENKQVVDDLYNGLYRKRQLGYGGLFKIIKKELALD
                     DAENGDLIHTSEDNDSLSEGTKIVAIWNAIKQNYYLK"
     gene            2507..2812
                     /locus_tag="VLL59_001683"
     CDS             2507..2812
                     /locus_tag="VLL59_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HER6509783.1"
                     /translation="MAQINIRVTDEQKALINKLAKENEKSISAYIIDKICIESVYQND
                     SKRIDETKKDDEGLILLLMKQLEQKDMQIEQLHKIIYNKDTKLLEYDSKKSWWQFWK"
     gene            3113..3619
                     /locus_tag="VLL59_001684"
     CDS             3113..3619
                     /locus_tag="VLL59_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509784.1"
                     /translation="MKNKLFKIITTSLTIVTLGGVFVPSAIYANEVLQPETVVSLPSD
                     INRDQLTTEIISDIEKEGLPEILNERPKRQKRGAAGLMATLIAKYGVRYVKTQLPKII
                     YKHIGKYVGNKIGEAAFVRIFGNIVDWGTGAAIEQALAQALQAAGIDAGTANTVATVT
                     VTVASWLI"
BASE COUNT         1322 a          466 c          689 g         1143 t
ORIGIN      
        1 aaaaaaaata aaaaagagaa aatatattat gtatggtgct atttctgcag ctttattagc
       61 acttataaaa tattttttct ttaagtaact tgtattttta agacaaagca tattataaat
      121 atgttttgtc ttttttagtg tcattatatt cgattttttt acttacttag cgttcgtatg
      181 attctatttt gttgttgtaa attatttcaa caacaaaata gaatagcaat catttagtcg
      241 agcgtagcga caaattcaga tgacatcatc tcaataaggt tttagacacc ctaacaagcc
      301 gtttaagcga tttgtgtata caaatccgtt gcttgcctga atcagattgt aaaatggctt
      361 agaaggcaaa tatgagcctt ctgagaggtt ttagagataa gttaagcgat ttatgccgag
      421 aaaactttag tcagtaagct gaagcgattt agacttaacg tgtctagtcg gaaggctgaa
      481 agacgaacga ctggatacgt agtcaaaaaa aatagcgaaa ggttacttgc tgactaaagg
      541 aaattggaat aaaggaagcg gacttgaaga aaaaactatc acgtgctata attaagtaaa
      601 attttaagta agtaggtgag actatggaaa acattgtacc tgtatcagat atgcgttatt
      661 ataatcaaac gctgagtgat gtgtcggttg gttctcaagt tattttgacc cgtaacggga
      721 aagctgaata tgcggtagtc gatattgaag aatggagacg tacgaaagca acactacgct
      781 tgtttgagga attgcaaaag ggctatcgct ctctagcgaa tgaaaagact tatactccag
      841 atgagcttgc ggaacgacta ggggtggact gatgagttac aaagtgataa cttcgagtga
      901 aacagtccga gatatcgagg aagctgtttt ttacaaagag ggtctgggag tttatccaga
      961 aaatgtcgta aaattcaaga aagctgtcgt ttcaactatc cgaaagttag tggattcacc
     1021 caagattgga gctaatttgt cagcaagaat tgacgaagaa accgagatta aatatagtgt
     1081 gattgatgac tatatcctgt tttacgaaat tgaagctgat accgttaagg tattgcgatt
     1141 gttgccggct aaaactaact gggttaatac gattctgaaa tacctgtgat ataaaaaaga
     1201 cctgttaagg gtcttttttg ggtgaatttt gaacgaagtg aaaaaaagag ggctgggaag
     1261 cccttagaaa ccctcgaaga gggtttcttc ttatcttgat acttttagaa ataactctca
     1321 tgctaaaaag agtctctcta ccataattaa acccttggta ttattggatt tttagcacaa
     1381 aaaaaagctt gattctcagt caaaactttg atatgattta gtcaccacaa caaaaacata
     1441 gaaagagaga tgagtacaaa ctttttttgt gaattaattc ttttttgtac tccaattata
     1501 acatggtaaa tgaactaaat caagaggaag ttcttagaga taaaaacagt aaaggtaagg
     1561 atagagattg gcgaggtcgc aaaatcatga gcttgaaatt agctgatgtc tttgagaatt
     1621 tagggtataa aaaatcaatg attgaacgtg ttcaatcatg tggtgaagtt ttaaacttta
     1681 ttcgtcattc agacggttct ttaaaattat atcaagctta tttctgtaag aataagcttt
     1741 gtccaatgtg taattggaga cgttcaatga aatattctta tcagacttct cgtattgttg
     1801 acgaagcaat taaacgagaa tcaaaaggac gctttctctt tttgacatta acggttaaaa
     1861 atgttcctgg aagtgattta aataaaacat tatcttcttt aacacagtct tttgatcgtc
     1921 tgttcagacg agcaaaagtt aagaaaaacc ttattggata tcttcgttct gttgaagtaa
     1981 cacataatga attgactaat gaatatcatc ctcatattca tgttttatta atgcttaaaa
     2041 taagttattt caaaggtgga aattatatta ctcaaaaaga gtggggtgaa atgtggtcgc
     2101 aatctcttaa ggttgattat gttcctatga ttgatataag agcagttaaa gaaaaaggca
     2161 aaggtttaaa aggagctatc cttgaaaccg caaaataccc aaccaaacct atcaaattag
     2221 agatggaaaa taaacaagtt gtagatgatt tatataatgg tttatatcga aaaagacaac
     2281 taggatatgg tggattattt aaaattatca aaaaagaatt agctttagat gatgctgaaa
     2341 atggagattt aattcataca tcagaagata atgattcact ttctgaagga actaaaattg
     2401 tagcaatttg gaatgctatt aagcaaaatt actacttaaa atagtgtata gaatttgtat
     2461 aacatttgta tagcaggatt gctatgcact gtatagagag gaatttatgg ctcaaattaa
     2521 tataagagtt acagatgagc agaaagcctt aattaataag cttgctaaag aaaacgaaaa
     2581 atctatatca gcgtatatca ttgataaaat ttgtatagaa tctgtatatc aaaatgatag
     2641 caaacgtata gatgaaacta aaaaagatga tgaaggatta attttgttgc tgatgaaaca
     2701 attagaacaa aaagatatgc aaattgaaca actccataaa ataatttaca acaaagatac
     2761 taaactttta gagtatgatt ctaaaaaaag ttggtggcaa ttttggaaat gaagaatata
     2821 tttaaaaaag ttggaattat gttccaactt ttttgactaa gaaaattatt atttgagata
     2881 gtgcataaag agattaaaca ttataattat gataaaccta ggttggtttt cttagaatta
     2941 attatgtagt cagggttaca taattaacct acaactcctt aattatagca aaaaaataat
     3001 tataaaaaaa gacttgtatt ttaaaaaaaa tataataaaa ttaaagcgtt aactagttaa
     3061 tgctttaatt ttatgcagcg tttagttttt ttaagattta tggagttttt ttatgaaaaa
     3121 taaattattt aaaattataa ctacgtcttt aactattgta actttaggag gtgtttttgt
     3181 tccttctgct atttatgcta acgaagtttt gcaaccagaa acagtagtaa gtttaccatc
     3241 tgatattaat agagatcaat taactactga aattatatct gatattgaaa aagaagggct
     3301 ccctgagatt ctgaatgaac gtccgaaacg ccagaaaagg ggagctgccg gtttaatggc
     3361 aactctaatt gctaagtatg gggttagata tgtaaaaact caacttccga agataattta
     3421 taaacatatt gggaaatatg tgggaaataa aattggtgaa gcagcgtttg ttaggatttt
     3481 tggaaatatc gtagattggg gaacaggagc tgctatagaa caagcattag cccaagcatt
     3541 acaagctgca ggtattgatg ctggcacagc taacacagtt gctactgtga ctgtaactgt
     3601 agcttcatgg ctaatttaag
//
LOCUS       DAUNLR010000084         2840 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.084, whole genome shotgun sequence.
ACCESSION   DAUNLR010000084 DAUNLR010000000
VERSION     DAUNLR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2840
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.084"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..351
                     /locus_tag="VLL59_001685"
     CDS             <1..351
                     /locus_tag="VLL59_001685"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HER6509785.1"
                     /translation="KEMIKAIFYEHKERYGSVRITQELCRRGIHVNYKRVGRLLHQLG
                     LYAKGSRYQYKYYNRRCSSLTCPNLVNQCFQATGKNKLWLGDLTYIPTHEGILYVSVL
                     IDVYSRKIVGWAMG"
     gene            355..720
                     /locus_tag="VLL59_001686"
     CDS             355..720
                     /locus_tag="VLL59_001686"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HER6509786.1"
                     /translation="MQDKLVTEAFNQAYNREKPKEGGIVHTDQGSQYTGARFQDLLRW
                     KKCKSRMSRKGNPYDNALMEAFYKTLKRELVNDAHFATIEQAQLEIFKYSETYYNPKR
                     LHSALGYLSPVEFEKIVTH"
     gene            846..1001
                     /locus_tag="VLL59_001687"
                     /pseudo
     CDS             846..1001
                     /locus_tag="VLL59_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039767.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1048..1578)
                     /locus_tag="VLL59_001688"
     CDS             complement(1048..1578)
                     /locus_tag="VLL59_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HER6509787.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(1571..>2840)
                     /locus_tag="VLL59_001689"
     CDS             complement(1571..>2840)
                     /locus_tag="VLL59_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HER6509788.1"
                     /translation="EFPIVYISFSGGKDSGLLLNILLDFRDKYYPDREIGVFHQDFEA
                     QYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTALSSYEMFWYPWDDKTEDIWVRP
                     MPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYKQIHGNQKTVCILGNRASESLHR
                     YSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVEDIWHAYYKFSYSYNELYDLFYK
                     AGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKLLGRVQGVNFSNIYGRTKAMGYK
                     SIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKSIDFWHKTGGGLAEETINELIEK
                     GYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTTKDIPSWKRMCFCILKNDHICRT
                     MGFGLTREQQKIVAFLKEKYKTSLKELESE"
BASE COUNT          928 a          569 c          416 g          927 t
ORIGIN      
        1 aaggaaatga ttaaagccat tttctatgaa cataaagagc gttacggaag tgtacgaatt
       61 acccaagaac tttgtagacg cggcatccat gtcaattata aacgtgttgg tagactcctt
      121 catcagctag gtctctatgc taaaggaagt cgatatcaat ataaatacta taaccgtcga
      181 tgttcttcat taacttgtcc caatcttgtt aatcaatgtt tccaagcgac tggtaagaat
      241 aaattatggc taggagacct aacctacatt cctacacatg aaggaatact ttatgtgtct
      301 gtcttgatag acgtttatag tagaaagatt gttggttggg caatgggcta acgtatgcaa
      361 gacaagttgg taacagaggc tttcaatcaa gcttataata gagaaaagcc taaagaaggg
      421 ggaatcgtcc atacagatca gggttctcaa tataccggag cacgatttca ggacctactt
      481 agatggaaaa aatgtaagtc caggatgagt cgaaaaggta atccatacga taatgcactc
      541 atggaagcct tttataaaac attaaaaaga gagcttgtca atgatgctca tttcgcaact
      601 attgagcaag ctcagcttga gatttttaaa tatagtgaga cttactataa ccctaaacgt
      661 ctgcattcag ctttagggta tctctcacct gtagaatttg aaaaaatagt tactcattag
      721 cttaacttta tgtctatttt tcttgacaag tccagggtat gaagtcccct tatacacata
      781 ctttcaaaac agctctcaat cctctgtccg ctacaaaaat acgtcaccgc tgccctccag
      841 ctgcctcatt caacgacaaa cttgaagcca caaacagact catcaagggc attaagtaca
      901 atgcctttag atttcagaac tttgacaact ttaaaaccaa aatcctcatc gctttgaaca
      961 tccaaaaaga gagaaccaat ctgattctct ctcgttgtta atgataagtc acccactaca
     1021 gttgacaatg agtctcttac ttcctgttta ctcatttaat agctcttctg gttcccaaga
     1081 ttgattaaac tcatggtcct taaaaagaga agccaatcct gttatttgtt tcagtcttaa
     1141 aatttcatct ttatccattc ctaaatgttt tgcaatccag ttatcacttc gcccacactc
     1201 atgaagatcc tttacaatct gactcatcaa atcaacatca tgacttcctc tagctctatt
     1261 atgtcgaatg gtagaagcca ttcgatagtc taatgactta tcaataacag aaacaggtaa
     1321 tctcccactt tccctttcat aaatatctga ataatctagc attatacgat atctatgaaa
     1381 accatcaaca atactatacc gatcctcttc cttatcgtaa tagcaaacaa tcggcatagt
     1441 ataaccatca gattttatac tatcatacaa taatttcatt tcaggcggag caactgaatt
     1501 cggattataa tcatttggag aaatcttttc aattggaatt gatttaatct catagactgg
     1561 actaataaaa ttactcactt tctaactcct ttaaactcgt cttatatttc tcttttaaaa
     1621 aggctactat tttttgttgc tctcttgtca aaccaaaccc catagttcga caaatatgat
     1681 cgttttttaa aatacagaaa cacattcgtt tccagcttgg tatatccttt gttgttacaa
     1741 tatcgtctgt atcatcagga atttgatcta aaaaaataac ccttgaatgt ttaaaagagg
     1801 tataatttga aataccattt ctagcaatac gatatccttt ttcaattagt tcattaattg
     1861 tttcctccgc aagtcctccg cctgttttat gccaaaagtc tattgattta ttaaattttc
     1921 taacataatt atttcttaac ctcactggta gcgtcgataa aagaaactga gtatacgact
     1981 tccacgaatg accctttggt aaagcaattg atttatatcc cattgcttta gtacgtccat
     2041 aaatattcga aaagttaact ccttgaacac gtcccaaaag ctttacccaa gtttcttgat
     2101 ctattattct ataaagattt aggctatcaa cagcatagtc ttgaaaagga gatgcaactc
     2161 tcatttgtga tggttttaaa cccgctttat aaaatagatc ataaagttcg ttataagaat
     2221 aagaaaactt atagtaagca tgccatatgt cttccactga ccaatcatat aagggagatg
     2281 ctgtccagac atctttgaat tgtttggtaa tccagcattc cttttgataa ccatactttt
     2341 tattgataaa accactatat ctgtgtaagg attctgaagc acggtttcct aatatacaaa
     2401 ctgttttttg atttccgtga atttgtttat accacctacc aaattgtttc gctaaatcct
     2461 cctgattcat tttataacga taagtagtaa ttgaattatt ttccaaatta ataacataat
     2521 cttgagatgg cattggtctt acccagatat cttctgtttt gtcatcccac ggataccaaa
     2581 acatttcata actactaagt gcagttctag tagccatcgg taagcacacc caatacaaag
     2641 aaactttttt tctaccttct aaagaagtga atgtttcttg aacatatttt gttgttaaac
     2701 tgtactgtgc ttcaaaatct tgatgaaaca cacctatttc tctatccgga taatatttat
     2761 ctctaaaatc cagtaaaata ttaagaagta acccactatc ttttccacct gagaaggaaa
     2821 tatagacaat aggaaattca
//
LOCUS       DAUNLR010000085         2708 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUNLR010000085 DAUNLR010000000
VERSION     DAUNLR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2708
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.085"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            209..457
                     /locus_tag="VLL59_001690"
     CDS             209..457
                     /locus_tag="VLL59_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HER6509789.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            494..1105
                     /gene="amaP"
                     /locus_tag="VLL59_001691"
     CDS             494..1105
                     /gene="amaP"
                     /locus_tag="VLL59_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HER6509790.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFNIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1116..1304
                     /locus_tag="VLL59_001692"
     CDS             1116..1304
                     /locus_tag="VLL59_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HER6509791.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1317..1856
                     /locus_tag="VLL59_001693"
     CDS             1317..1856
                     /locus_tag="VLL59_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HER6509792.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1897..2097
                     /locus_tag="VLL59_001694"
     CDS             1897..2097
                     /locus_tag="VLL59_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HER6509793.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKIK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2108..2596
                     /locus_tag="VLL59_001695"
     CDS             2108..2596
                     /locus_tag="VLL59_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HER6509794.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
BASE COUNT          908 a          369 c          551 g          880 t
ORIGIN      
        1 gtggtcactt tataaaatat tatcaaaata acattttata ggattttgaa atatcggtat
       61 tcaaacaaaa aataaactaa cactttatta tttagtttat atagtcactt tttgaaagtc
      121 gactattaaa agactattgc ttgaagaatg acagctgtta ttcttccttg gacaaaaggt
      181 acaggagtat ctaaaaagga gaattatcat gggacttatt tggactttaa tcgtcggtgc
      241 gcttattggt gtgattgctg gagcacttac taaaaaaggt ggttcaatgg gctggattgc
      301 aaacatcgct gctggtctag ttggttcttc cgttggtcaa gctttacttg gttcatgggg
      361 cccttcttta gcaggaatgt ctttgatccc gtcagttatt ggtgccgtta tcgttgttat
      421 gatcacttct tttgtactaa acaaaactaa caactagttt cctctttatt tagtaagtac
      481 ttacaaatag agaatgttaa gtagaaaaga ggtctgtatg tcaaaattgt taaagattag
      541 ttattgtctt gtcggacttg ttctattgtc tgtttttgga tgggtagttg gaataaccgg
      601 aggctatata tatttacctt atagttatcg ttggctaagt tggggtatgg atagttttcc
      661 caatctctta gattcagctt tatcctatta ttacttctgg acagcccttg tattatttgt
      721 tataacattt cttgccttat tagttattat tttataccca agaatttata ctgaggtcca
      781 gttacgccat aaaaataaaa aaggaacact tttattaaaa aaatcggcta ttgaaagtta
      841 tgttgcgacc gctattcaaa ctgcaggttt gatgccaaac ccaacagtca cagctaaatt
      901 atataagcgg aagtttaaca ttatcgttaa aggacgttta gcttctcgtg tagcagtggc
      961 agatcaaatt agtggcgtga aagaagggat cgaaaaaggt ttaaccgagt tcttcggaat
     1021 taattatcct gttaatttca aagtttatgt taaagatatt gctgattctg atcgtaaaca
     1081 tattaccaga aatcgtgtag aataggagat ctatcatgga attttatgaa aaattcaagt
     1141 accctattat tggtggcttg gtggggctaa ttattgccat attgctcatg gcttttggtt
     1201 tattcaaaac gctactagca attattttca ttattttagg aatatatggt ggcctgtatg
     1261 ccaaaaaaac aggtattatt gatcaatttc ttaatcgtaa ataaaggaga cttattatga
     1321 ctgaaactta tattaaaaac acatctaaag acttaacttc agcaattcgt ggccaattaa
     1381 catatgatga taaagtaatt gaaaaaattg ttggtttagc acttgaaaat gttgatgggt
     1441 tactgggtgt aaatggtggt ttttttgcta acctaaaaga taaattagta aacaccgaat
     1501 ctgtacgtga tggcgtgaac gtggaagttg gaaaaaaaca agttgccgtt gatcttgata
     1561 ttgtcgctga atatcaaaag catgtgccga ctatttatga ctctattaaa tcgatcgttg
     1621 aagaagaagt gaagagaatg accgatctgg atgtgattga agttaatgtt aaagtagtcg
     1681 acattaaaac aaaagaacaa tttgaagctg aaaaagtaag tttacaagac aaagtttcag
     1741 acatggcacg ttcaacatct gaatttacga gtcatcaagt tgagaatgtt aaagcttcag
     1801 tggataacgg tgttgaaaaa cttcaagatc aaaaagctga gccacgtgta aaataatcat
     1861 atgtcgtcaa ttaggtaagc taaaggaggg tttattgtgt cagatgaaaa atataatgcg
     1921 aaattagatc aagctggtgg caagttaaaa gaaggatttg gtaagatttc tggagataaa
     1981 tctttagaaa ctgaaggtaa agtagataaa gttactggaa aaattaaaga ggttattgca
     2041 gatgccaaag atactgtaaa aggattagct aaaggcttag ataataaaga taaataaagg
     2101 ggacatgatg gaaaaaactc aaattaaaag cactcttact tatgacgata aggtcatcga
     2161 aaaaattgtc ggtcatgctt tggaaaacgt tggcggatta ctagctgtaa caggtggatt
     2221 tttctcaaat atcaaaaata atttggtgaa ttctgagtct gtaactgatg gtgtttcagt
     2281 tgaagttggt agcaaggaag tagcagttga tttagcaatc attgtagaat acggtaaaga
     2341 tattcctgct attgcagaat ctattaaagc tattgtttct caaaacgttg acagtatgac
     2401 acatttgaaa gttgttgaag tcaatgtgaa cgttgttgat attcgtacta aggaagaaca
     2461 tgaagctgct agcgttactg ttcaagatcg tgtcactagt gcagcttcaa gtacttcaca
     2521 atttgtatca gaacaaacag aaaaattaaa agatactatc tctgatactg taaatagtga
     2581 tgaggcagct aaataagcaa tcgtctagga agtattattg actagtggtg ataagtttga
     2641 gctggtattt accagctctt tttgtcacgg ttaaaaagat acggactatt gtcatctctc
     2701 taaaaata
//
LOCUS       DAUNLR010000086         2667 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUNLR010000086 DAUNLR010000000
VERSION     DAUNLR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2667
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.086"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..1363
                     /locus_tag="VLL59_001696"
     CDS             <1..1363
                     /locus_tag="VLL59_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509795.1"
                     /translation="SLVRNLTINLQKLVIKDRTALIGDKQLPITIYYRGENEKFPTGI
                     VKVESDSVEGLELFDKTIKEIVGNESRFGKFTCIYDGISTYYSTEIYSELHEIERRTQ
                     EFLREAFFLSDKSGELKEYQATIKKMDSSDFSFSKLINEIFKASDITDTFIDHVRACV
                     EFGTVPNGDLLPKSFWDSLDDSLLDDKEQGLEINNLLNEIRSTRNTIAHCKEFKKKDY
                     INCIEQVKKLKQALDKIIASIESTDISKMSREVSRINNSLQADNDYIKQKYFIEYDIF
                     EKDILARTGLLEIDWENVSDDIEPLKIHRNFYESISEKTDSEVIEEIKNLEDINFTDE
                     KGNDLDDLTIIVPAQDEGFKRVFLGQREWYDIRIGKSKRNRIKYIAGYEVAPESGVKY
                     WAEVDKIVPSDNYVGYWKVIFKGEVKEYSEYKRLGNTWPPQNSRYVSKKALDEAKYLS
                     DVF"
     gene            1383..>2667
                     /gene="purB"
                     /locus_tag="VLL59_001697"
     CDS             1383..>2667
                     /gene="purB"
                     /locus_tag="VLL59_001697"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HER6509796.1"
                     /translation="MISRYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEQYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDTKVTSCLTQEEIDELFNPIYYTKRVDDIFKRL"
BASE COUNT          915 a          407 c          586 g          759 t
ORIGIN      
        1 atctttagtt cgaaatttga caatcaatct tcaaaaacta gttattaaag atagaactgc
       61 attaataggg gataaacaac ttccaattac gatatattat cgtggggaga atgaaaagtt
      121 tcctacggga atagtaaaag ttgaatcaga ctcagttgaa ggattagagt tatttgataa
      181 aacgataaag gaaatagttg ggaatgaaag tagatttgga aagttcacat gtatatacga
      241 tggaataagt acatattatt caacagaaat ttattctgaa cttcatgaaa ttgagcgtcg
      301 aacacaagag tttttaagag aagcattttt tctgagcgat aaaagtgggg aattgaaaga
      361 atatcaggca actatcaaaa aaatggatag tagtgatttc tcattcagca aattaattaa
      421 tgaaattttt aaagcaagcg atataactga tacatttatt gaccatgtta gagcgtgtgt
      481 tgaatttgga acagttccaa atggagattt attaccaaaa agtttttggg atagtttaga
      541 tgactcttta ctagatgata aagagcaagg tttagagatt aataatttat taaatgagat
      601 tcgttcaaca agaaatacaa tagctcactg taaagagttt aaaaagaagg attatattaa
      661 ttgtatagaa caagttaaaa aattaaagca agcattggat aaaataatag cctctataga
      721 gtctacagat atttctaaaa tgtcacgaga agtgtcacgc ataaataact ccttacaagc
      781 cgataatgac tacatcaaac aaaaatattt tatagaatat gatatttttg aaaaggatat
      841 attagctagg acagggttat tagaaattga ttgggaaaac gtttctgatg acatagagcc
      901 cttaaagata catcgtaact tttatgaatc aattagtgaa aaaacagatt ctgaagttat
      961 agaagaaatc aaaaatttag aagatataaa tttcactgat gaaaagggta atgatttgga
     1021 tgacttaacc attattgttc ctgcgcaaga cgaaggattt aaaagagtct ttctaggtca
     1081 acgagaatgg tatgatatac ggataggaaa atcgaaaagg aataggatta aatatatcgc
     1141 aggatatgaa gttgcaccag agagtggtgt aaagtactgg gctgaagtgg ataaaatagt
     1201 tccttcagat aactatgttg gttactggaa agtaattttt aaaggagagg tgaaggaata
     1261 ttcagaatat aaaagattag gaaatacttg gccccctcaa aacagtagat acgtatctaa
     1321 aaaggcttta gatgaagcta aatatttatc ggatgttttt taattaaagg agaaaaaaca
     1381 aaatgatttc acgttattca cgccctgaga tggcggcaat ttggacagag gaaaataaat
     1441 accgtgcttg gttggaggtc gagattttgg ctgacgaggc atgggctgag ttgggtgaga
     1501 ttcctaagga ggatgtggct aagattcgtg agaaggcgga ttttgacatt gaccgcattc
     1561 ttgaaattga gcaggacacg cgtcacgatg tggtggcttt cacgcgtgcg gtttctgaga
     1621 cgcttggtga ggagcgcaag tgggtgcact acggtttgac gtcgactgac gtggtggaca
     1681 ctgcctacgg ttacctctac aagcaagcta acgacattat tcgtcgcgat cttgagaatt
     1741 tcacaaatat tgtggctgat aaggctcgag aacataaaat gaccatcatg atgggtcgta
     1801 cccacggtgt tcatgccgag ccaacgactt tcggtctcaa gttggcgact tggtacagcg
     1861 agatgaaacg taatattgag cgttttgaac atgctgccgc aggtgtggaa gctggtaaga
     1921 tttcaggtgc cgttggtaac tttgctaata tccctccatt tgtggaacaa tatgtctgtg
     1981 acaaattagg cattcgtccg caagaaattt caacacaagt tcttccacgt gaccttcacg
     2041 cagaatattt tgcagtgctt gcaagtattg caacttctat cgaacgtatg gcgacagaga
     2101 ttcgaggtct gcaaaagtca gaacaacgtg aagttgaaga attctttgcc aaaggtcaga
     2161 aaggtagctc tgctatgcct cacaaacgca acccaatcgg ttcagagaac atgacagggc
     2221 tagcgcgcgt gattcgtggt cacatggtga cagcttatga gaacgtgtca ctttggcatg
     2281 agcgtgacat ttcgcactca tcagctgagc gtatcatcac acctgacaca actatcttga
     2341 ttgactacat gctcaaccgc tttggtaata tcgttaagaa cttgactgtc ttcccggaaa
     2401 atatgatgcg caatatggaa tcaacttttg gtttgattta tagtcaacgt gttatgctca
     2461 aattgattga aaaaggaatg acacgagaag aagcttatga cttagttcaa cctaagacag
     2521 cttattcctg ggacaatcaa gtggatttca aaccactttt agaagaagac accaaagtta
     2581 cctcttgtct tacacaagaa gaaattgatg aactatttaa tccgatttat tacacaaaac
     2641 gtgttgatga tatttttaag cgtttag
//
LOCUS       DAUNLR010000087         2519 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUNLR010000087 DAUNLR010000000
VERSION     DAUNLR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2519
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.087"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..243
                     /locus_tag="VLL59_001698"
     CDS             <1..243
                     /locus_tag="VLL59_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HER6509797.1"
                     /translation="IAKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
                     GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
     gene            complement(368..616)
                     /locus_tag="VLL59_001699"
     CDS             complement(368..616)
                     /locus_tag="VLL59_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HER6509798.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(670..1590)
                     /locus_tag="VLL59_001700"
     CDS             complement(670..1590)
                     /locus_tag="VLL59_001700"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HER6509799.1"
                     /translation="MSNEFINFEKISRESWKTLHQKSKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHNIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1825..2451
                     /locus_tag="VLL59_001701"
     CDS             1825..2451
                     /locus_tag="VLL59_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HER6509800.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLKTLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSIKQA"
BASE COUNT          863 a          347 c          457 g          852 t
ORIGIN      
        1 atagcgaaaa caacggacaa aaatttatta atttctgtta ttgataatgg tccagggata
       61 acagatgaag aaaagaaaaa gatttttgat cgtttttatc gagttgacaa agctagaaca
      121 cggcaaacag gtggatttgg cttggggttg gctttagctc agcaaatcgt gatgtcttta
      181 aaaggaaata ttacagtaaa ggataatgat cctaaaggta gtatttttga agtcaaacta
      241 taagctaaaa agggcgacca ataaggtcag cccttttaaa gttattttta actgtcaacg
      301 ctttattgta ttttttgagt ttttaccgta taaaaaaact ccagctggag ttttcattgg
      361 atatttatta gccaagtttt gcagcaaggc gtgctttatc gcggcttgct ttgtttttgt
      421 gaatcaaacc ttttgattca gctttatcga tgcttgaaga agcagcgcgg aaaagctctt
      481 cagatgggtt agcttcaaat gctttgatag cagtacgcat agctgatttt tgtgctgagt
      541 ttttttcgtt tgctttaacg ttaagttcag cgcgtttaat agctgattta atatttgcca
      601 atgttttcac ctccaaatta atctaactac attattatat agaaaatata tgcgtttggc
      661 aaccctttat cactttttga ggtaaatttc atcaatttta tgatcagcac ttttatgtaa
      721 aattaattca gcacggttac gtgtaggttc aatgaatttt tcaagatttt ctaaattaac
      781 ggttttccaa acgttgcgcg caaatgctat agcctcagat cgaggtaatt gtgcatattg
      841 ggcataataa ttatgagggt cacgttttgc taattttaaa atgcttagaa accgttcaat
      901 gtaccaggtt tcgatgtgac tgctgtctgc atcaatataa atagaaaaat caaagtaatc
      961 actcatatat aaacgattgt tttgttgatt ttgaaaaaca ttaatacctt cgacgataag
     1021 gaagtcaggg ttattaaatg attgtttttg atttgggata atatcgtaaa tattatgaga
     1081 atagacgggt gcaaaagcag tttgaccatt tttgatggaa tctagaaaat ctaagagaag
     1141 ttccatatta taagattctg gaaatccttt acgatttaac agcccttgtt caataagaaa
     1201 ctgattagga tataaaaaac catcagtcgt taccagttcg acttgactat tggggtgcgt
     1261 tcgtgataat aaaagttgta aaagacgact agttgttgat ttaccaacag ctactgaacc
     1321 agaaattcca ataataaaag gtcttaattg aatgtctttt tttagaaaaa ggcttttaga
     1381 aaaagaaaga ttttcttgcg caattttgta aacctggatc agattaatta atggaaggta
     1441 gatatcaatg acatcgttaa tactgatgtt atcatttaag ctagtaatac ttttaagttc
     1501 ctcttgtgtg aggagagctt ttgacttttg atgtaatgtt ttccaagact ctctagaaat
     1561 tttttcaaag ttaataaatt catttgacat ggtagctcct aatcatttga cagtgcttac
     1621 attataccat tttagttaaa aaataaataa tttttcgtta gtatttacac gaaaattaat
     1681 acaattaact caaaaaagcc acacattcct agtacaatta tcctgctata ttctaacaaa
     1741 tagttaaagt tcggttttta tttgtaatat agataaaatt gttaaaaaac aagcgtcttg
     1801 taaaccattt caaagtatga tagaatgaaa aagtacctta aaaagatagg aaaaatgatg
     1861 acaaagatgt attatgatga aaatccagat agcctacacg atattcatga agtaaaagta
     1921 gagctgctta atcatccctt tacttttttg acggattcag gtgtcttttc aaagaaaatg
     1981 gttgatttcg gtagccaagt attattaaag acactaaatt tcaaggagaa cgaacgtgta
     2041 ctggacttag gttgcggcta tggccctctt gggattagtc tagccaaggt tcaaagggta
     2101 gacgcaacct tagtggacat caataatcgt gctcttgatt tagctagaaa aaatgcaact
     2161 aataaccaag tggcagtaac tatttttcaa tcaaatattt atgaaaatat tagtggccat
     2221 tttgagcata ttattagtaa tcctcctatt agagcaggaa agagagtagt tcatagtatt
     2281 attgaaaaaa gcatagattt tttagtggtt aatggtgact taacgattgt gattcaaaaa
     2341 aaacaaggag ctcctagcgc taaagcaaaa atggcaacta tttttggtaa tgttgagata
     2401 ttaaggaaag ataaaggtta ttatgtatta agaagtataa agcaagccta atttaaataa
     2461 tcaataattg ctcattaaat taggtttgct taaatagtaa agagttattt ttaaattat
//
LOCUS       DAUNLR010000088         2503 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUNLR010000088 DAUNLR010000000
VERSION     DAUNLR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2503
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.088"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(129..518)
                     /locus_tag="VLL59_001702"
     CDS             complement(129..518)
                     /locus_tag="VLL59_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HER6509801.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            complement(528..1499)
                     /locus_tag="VLL59_001703"
     CDS             complement(528..1499)
                     /locus_tag="VLL59_001703"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HER6509802.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNYAGIIGAASLARQFITK"
     gene            complement(1504..1707)
                     /locus_tag="VLL59_001704"
     CDS             complement(1504..1707)
                     /locus_tag="VLL59_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HER6509803.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            complement(1849..2376)
                     /locus_tag="VLL59_001705"
     CDS             complement(1849..2376)
                     /locus_tag="VLL59_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HER6509804.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
BASE COUNT          749 a          558 c          441 g          755 t
ORIGIN      
        1 aaaaaactgg ttttaatcaa ttgtaaatgt tttcagactt tcagcaagtc tggatacagc
       61 aaaaaaagga attaaggttt ttgagacagt gactaccttt attcccctta actccacgtt
      121 actcttaact aggttgtttg tttaactttg ccatcccaat aatcaatacc gtcttttaag
      181 acataaacgt cttcaaagcc agctttttta agttttttga ccgcaggcac acggtactgg
      241 ggacgcatat tttcgtaaat aagaacaggt ttgtccttgc gaagaccttt gatagcagca
      301 tcaaattgtt gcgctggaaa atttcgagct cctaaaatat gcttagctct aaaagccgct
      361 ggctctcgta aatcaatcaa ttgaccttga cgcatcacgt ctttaaaagt ctcgttatca
      421 acctgctttg ccatttttcg aaaagagaaa tagttccatg tataataacc aacaatgccg
      481 acaagaagta accataagat aagtgtgatt ggagacatat ccccctccta ttttgtgata
      541 aattgtcgag caaggctagc tgcaccgata attccagcat aattgccaag ctctgcaatc
      601 ttaattttag ttgaatacct cacttgtggg aaagtgaagg tcacaaagta tttttcaata
      661 cgtgagcgta gaaattctcc tgctgctgac acacccccac cgataaccac tgagtctgga
      721 ttcaagatat tggaaatatt tgctgaagca aggccaaggt agtaaccaac cttttccaca
      781 acagaatcag caaaggaatc ccctgcttca gccgccatga aaatgtcttt actggtaaca
      841 ccttcaccat tgtcaatagc tgctttgatg gctgaatccc cttcgtaggc ttctgccagt
      901 aaacgtgcca ctttgacaac tcctgttgct gaagctactg tttccaaaca gccgtgtgag
      961 ccacaagtac aagcaaagcc attttctggc tcaacaatca tgtggccgat ttcaccacct
     1021 gctcctgcaa caccatgaat caagttacca tcagcaataa tgcctccacc gacacctgtt
     1081 ccaagtgtca tgaagacgac atctgggtta ttttcaccag cacctaccca acgttcacca
     1141 agggcagcca cattggcatc attgtcaatg gcaaaaggaa tgcccaattc tttttcaaca
     1201 acggaaccga cttcttgggt ttctttccaa ttaaggttga atgccccagt aactgtatta
     1261 gtatcacggt caaccgctcc tggtgatccc ataccaattc ccacaaagtc agcactgctt
     1321 agaccataca agtctaagcg atgtttgatg gaagcgatga tatcagggac aatatgtttg
     1381 cctccttcta aaatattagt ctcaattgcc catttttctt ggacttctcc tgctgctgtt
     1441 aaaattccaa atttaatggt ggtaccacct aaatcaatcc ccagtaattt ttgactcatt
     1501 tgtctatcct tctttttcca attctaatct atgctcacgt cgcaaaatta actccgcatt
     1561 taagtaatcc ctcttatcca ataagccgct atcatagaga cgctgaagtt caatcttcat
     1621 catttcaata tcataaagac gtttgccaag gtaaacaaaa atgccaaagt tttttagcaa
     1681 ttgttgcaca tcatatagtg ttttcatata agtagatttt agcaaattct acggcagatt
     1741 tcaagacaag tatggaatcg ctttctatat ttctgaaaat gaatcgatga ttccataaaa
     1801 aagaagccaa ttttatcatt gacttctttt atcctaaggc ataatcaatt agagtgctgg
     1861 gccttgtcca cgctctgctt ggagcatcca aatggttttt tcagcctctg tcttagctgc
     1921 tgtaaacaaa tcgtttgttc cagcatcgcc ttcttcatcg gtaatatcca aaccaacttg
     1981 gtaaaggctg ctgaggtaaa ggtaaacttc gactaatctt gctaaatgct gagcaactgt
     2041 tttatcgtaa gtaccttttg cttcgtccaa tttagagtgt ttagaaaact cagctagggt
     2101 agaataaggc gctccgccaa tagtgatcaa acgctcgctc atttcatcta aattagcatt
     2161 caagctatca agtaattcat ccattttggg gtgaaggtac aagaaacctg gaccacgcat
     2221 ataccagtgt acttggtgca caatagatgc agccacagat aagtcagcga cagcttggtt
     2281 taaaacagct ttagtttttt cattttttga tgcttctttt ttagaaatat tgtgagttac
     2341 tgaagcataa atattttcaa cgagtgtgtt tgtcataata acatctcctt acttttcagc
     2401 ttaaagggca agaatggagg gggaactaac cctaacgtga taaacataag aaagggttaa
     2461 ggacctaatc ctattcgaca ataacggaat aatcctaatt gga
//
LOCUS       DAUNLR010000089         2492 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUNLR010000089 DAUNLR010000000
VERSION     DAUNLR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.089"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..236
                     /locus_tag="VLL59_001706"
     CDS             <1..236
                     /locus_tag="VLL59_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HER6509805.1"
                     /translation="ILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKRTKKEKQLAER
                     LKDDNFVKKYARAKYYLSREGEMIYPIPGLLPK"
     gene            371..1657
                     /locus_tag="VLL59_001707"
     CDS             371..1657
                     /locus_tag="VLL59_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HER6509806.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            1654..>2492
                     /gene="tilS"
                     /locus_tag="VLL59_001708"
     CDS             1654..>2492
                     /gene="tilS"
                     /locus_tag="VLL59_001708"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HER6509807.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTA
                     KQG"
BASE COUNT          935 a          369 c          390 g          798 t
ORIGIN      
        1 ttattttgcc aacttataat cttgtcaaaa gttatgttga ttttgaaaag caaaatcaac
       61 aggtggttaa attaaaaaaa gagtataatg aattgtcaaa gaggacaaaa aaagaaaaac
      121 aattagcaga acgactaaaa gatgataatt ttgtcaaaaa atatgctagg gcaaaatact
      181 atttatcgcg tgaaggagaa atgatttatc ctattccagg actattacca aaatgatgat
      241 ggacaatatt gtaaaaaaaa tagaagcatt tcttgctttt tctgataaaa aattagcaga
      301 gctgcaacag gaaaatcaaa aagttaaaga agaaagtcag tatattcaaa aaaactagaa
      361 aggagtcaat atgagaaaat tattagcggc tatgttaatg actttttttc tgactccttt
      421 accagtgatt agtacagaaa aaaaacttat attttcaaaa aatgctgttt atcaattgaa
      481 acaagatgtc gttcaatcaa cacaattcta taatcagcta ccctctaatc caaatcttta
      541 tcaagaaacg tgtgcctata aagacagtga tttaactcta ccagcaggaa gattaggtgt
      601 aaatcaacca ttacttatta aatcgcttgt gcttaacaaa gaatctttac cggtttttga
      661 gttagctgat ggtacctatg ttgaggctaa tcgacaattg atttatgacg atattgtact
      721 taatcaagta gatatagata gctatttttg gacacaaaag aaacttaggc tttattcagc
      781 cccttatgtt ttaggtacgc aaacaattcc ttcttctttt tcatttgctc aaaaagttca
      841 tgccactcaa atggcacaaa caaaccatgg aacttattat cttattgatg ataagggctg
      901 ggcatcacaa gaagatctag ttcaatttga taaccgcatg ttaaaagtcc aggaaatgct
      961 cttacaaaaa tataataacc caaattattc aatttttgta aagcaactca acacacaaac
     1021 aagtgctggt attaatgctg ataaaaaaat gtatgctgca agtatctcga agttagcacc
     1081 actttatatt gttcaaaaac aattacaaaa aaagaaatta gcagagaata aaactttgac
     1141 ttatactaaa gatgttaatc atttttatgg agactatgat ccattgggaa gtggtaaaat
     1201 tagtaaaata gctgataata aagattatcg tgttgaagac ctactgaaag ctgtagcaca
     1261 acaatcggat aatgtagcaa ctaatatttt aggttattat ctatgtcatc agtatgataa
     1321 agctttccgc tcagagataa aagctttatc aggtatcgat tgggatatgg agcagcgctt
     1381 attaacttct cgttcagctg caaatatgat ggaagctatt tatcatcaaa aaggccaaat
     1441 tatttcttac ctttcaaata ccgaatttga tcaacaacgt atcacaaaaa atattactgt
     1501 tccagttgca cataaaattg gtgatgctta tgattataaa catgacgttg ctattgttta
     1561 cggtaatact ccatttattt tgtctatttt tacaaataaa tcaacctatg aagatattac
     1621 ggctattgca gatgacgttt atggtatttt aaaatgatga cctatcaaga aatttttaat
     1681 gaaataaaaa ataaagccta ctttaaaaat catagacatg tgttaatagc cgtatctggt
     1741 ggagtagatt caatgaattt attgcacttt ttatacctgt ttcaagacaa attgaaaatt
     1801 cgtattggta ttgctcatgt taatcacaaa caaagatcag aatcagattc agaagaagct
     1861 tatttaaagt gttgggctaa aaaacatgac atacctattt atgtttctaa ttttgaagga
     1921 atattttcag aaaaagcagc acgtgattgg cgctatgctt tttttaaaag tattatgtta
     1981 aaaaataact attcagcttt agtaacagct caccattcag atgatcaagc agaaactatt
     2041 ttgatgaggc taattagagg aagccgattg aggcacttgt cgggtataaa aagcgtgcaa
     2101 ccatttgcca atggtcaact tataagacct tttttaactt tctcaaaaaa ggacttgcca
     2161 gaaatttttc attttgaaga ttcttcaaat agggaattat catttttaag aaatagagtt
     2221 agaaataatt atttaccatt gttaaagcag gaaaatccta ggttcattca gggattaaat
     2281 caattagcac ttgaaaatag cttacttttt caagctttta aggagctaac aaatcatatt
     2341 actaccactg atttaacaga atttaatgag caatctaagt ctattcaata ctttttgtta
     2401 caagattatt tagaaggttt tccagattta gatttaaaaa aatctcaatt tactcaatta
     2461 ttgcaaatta tccaaactgc taaacaaggc ta
//
LOCUS       DAUNLR010000090         2473 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUNLR010000090 DAUNLR010000000
VERSION     DAUNLR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.090"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(387..725)
                     /locus_tag="VLL59_001709"
     CDS             complement(387..725)
                     /locus_tag="VLL59_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509808.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
     gene            complement(1064..>2473)
                     /gene="cls"
                     /locus_tag="VLL59_001710"
     CDS             complement(1064..>2473)
                     /gene="cls"
                     /locus_tag="VLL59_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HER6509809.1"
                     /translation="TILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLI
                     YTKLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFP
                     IYNNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEG
                     VEVRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDG
                     EVSFTGGINLADEYINEVERFGRWKDAGLMLEGEATDSFLILFLQMWSITEKELIIAP
                     YLSDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEME
                     HALRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMSSGVKIYEYQPGFVHSKVFI
                     SDNTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLKQ
                     RPWYQKLIGLLVRTIAPLL"
BASE COUNT          863 a          459 c          369 g          782 t
ORIGIN      
        1 gcctggataa aaaatctaac tatagaagat cggtttttat aacaaacgaa agcatggttt
       61 tgaaattaaa aaaacataat tttagactac ttaaaaattg gaaactacta gctgtcactt
      121 cgaagtagta ttatcctaga ctgtttcatt aagactaagg atatgattta tcaaataaaa
      181 gtttattcac ctcaactaag aaaggagggg agtttccaaa atgtagcaaa aaataaacag
      241 aaagttaaac taaagcttga atgcttaagt tctatgtaat atagaataca cctaatagta
      301 gcaaaaaaaa tacctaacag atttttatct gttaggtatt taaaccttat cccctcaaag
      361 acactaaaat gccattggaa gcgtttttat tttatttgtt caaaacgcaa gtgaaccaca
      421 atcttatcac catagccatt gcgctctaaa tctcgctgaa gacgataaga aatgtaatgt
      481 tctgcaatgg taatatatcc agcatccatc aaacgattct ccacaaggga ttggaccata
      541 ttgatagtag gacgttctac atgtgcttct tctaaatcaa taactacttt tttagtaaca
      601 tgtgttaagt tttgtcgcca cgtgtcatca ataacataga ccgtccttgc tgctttaata
      661 attgcttgat aaattttatc tggatcaaaa tcagcaacgt ggccatcacg cttaataatt
      721 tgcataagat catctctttt cataagtttt catctctaat tacattatgc aaatgttatt
      781 agcatttgtc aagtcatagc actcataccc aaaaaactac tttcttactt tgaaacacaa
      841 taatcactga tacattctga attttaacta agataataaa attaaaaaag gattgagaat
      901 atctcaatcc aaggggcatt cttaataaat aagattgtga taaaatggtt cacacagatt
      961 atcaaagtcg gcttcccgcc ttaatgacct cccctgcgca aaagtgactt tgcagtcaca
     1021 atcgactcat cgcatacaga tattataaca tattttacga aaattacaag agaggggcaa
     1081 ttgttcgtac taataatcct atcaattttt gataccaagg acgttgcttc aaatgatctg
     1141 atgtcatcaa tagtgattgc ttttgagctt cattaaagtc attcacaata tcagcaataa
     1201 ctgacacacg atataaataa gtcgcgcatt caaaatgatg ataaaggcta cgatagtcta
     1261 agttaattgt tccgacaact gcttttgtat tatcagagat aaataccttt gaatgaacga
     1321 accctggttg atactcataa atttttactc cagaagacat caaagcttta taataggttt
     1381 tagctaaggc atatggtacc cccttatctg gcactcctgg cataataatt cggatatcta
     1441 ctccacgttc tgatgcaaat cgtaaagcgt gttccatctc gctatctaaa ataaggtaag
     1501 gtgtcatgat ataaacgtac tctttagcat gatttaaaat gtctatataa acatttttac
     1561 ctattttatc agtatcaagc ggggaatcac cgtagggaat aacatagcca tctgaaggaa
     1621 gttttaaaga atgatctgaa agataaggag caataatcag ttctttttct gtgatagacc
     1681 acatttgtaa aaacaaaatt aaaaagctgt ctgttgcttc accctcaagc attaaaccag
     1741 catctttcca gcggccaaaa cgctctactt cattaatgta ctcatctgct agattaatac
     1801 ctccagtgaa tgatacctcc ccatcaataa cgacaatttt tcggtgatct cgataattgt
     1861 aataggtaga gataaagggt gaaatcggta aaaatgattt agctttaatc cctatttgtt
     1921 ctaatctctt ggcgtaatct gatgatagcg ttgatagttc gttcatgcca tcaaacaaca
     1981 ccctaacttc tacaccttca ctgacttttt tttctagaat actaaggatt tctccccaca
     2041 tttggccttc tgcaataata aaaaattcaa gaaaaatgta ctttttagct aagaataact
     2101 gttcttttaa actatcaaaa aaagtttcac ctgttgggaa gtaagttacc cttgtattat
     2161 tataaatcgg aaagttgcca cgacttcttt ctaagtactg tactaaatga tatgtggttg
     2221 atgtgctatc ctttaatacc tctaatatag cgtcatcatc gctaaggtaa ggtgcagaca
     2281 gatctacaag atgatttatt ctctgtttta gccctctgta accccaatcc aattttgtat
     2341 aaattaaaaa cagtgaccct agtaatggag caatcataat caaaattaac cacgtcattc
     2401 ttgaaatagc atccatatca ctattaacta aatataaaac aatagtaata gcaaagacac
     2461 tttcaagaat cgt
//
LOCUS       DAUNLR010000091         2462 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUNLR010000091 DAUNLR010000000
VERSION     DAUNLR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2462
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.091"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(166..2376)
                     /locus_tag="VLL59_001711"
     CDS             complement(166..2376)
                     /locus_tag="VLL59_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HER6509810.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HIIGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTKNRE"
BASE COUNT          807 a          391 c          451 g          813 t
ORIGIN      
        1 tttattacca gtaatgtggg atatttagat ggtagcaaga agttttatag ctgatttgtt
       61 ttctttaggt ctaattagca tattttgatt actgataaac ttgaatatcg ccaataaaaa
      121 agaagcaaaa ttattatttt gcttctagtc agatcattaa attgattatt ctctattttt
      181 ggtgttatcc tcttttagtt cagaagttgc cgcgtcagct tctacgggat ttagttctaa
      241 gtaagatggt gctttaaaaa gtttctgagt tgatttatga ccatttttac tgtataaact
      301 tgttgactct gatccgagtt ttgctgaaat atctttcagt tgttttaact gcttagtgta
      361 gataaactgg ttaggatcaa tagcttttag accattttga gtatcaaagc gcaggagatc
      421 acccgtttga atagcgtcgc tagctgctag ttgttgagca acagcagagc gaatttcctt
      481 agttttggct atagtcattt catcgggatt agtgatttct aaacctgttt gcgtgttgta
      541 cagacgtcca ctatagttag tgtattcagg agtcatataa gtcccagatg ttcgttgtgc
      601 cacaatctgg ctattttgag gtgataataa atcttgtcct aattgaacaa actgactagt
      661 gtcaatacca attatgtgga gtaaagtagg aagagcatcg atttcaccgc caaaggtttc
      721 tttgatacta ccattcgtat aacctggaat atggatcata tacgggactc gttgtagcat
      781 agcattatca tattcagacc aagtttcaga atctttacca agaagtggag caagactaga
      841 attacgagaa tttgaaatac cataatggtc accatataaa acaaaaatag aattgtcgta
      901 caaaccagtg gctttcaagt aatcaaaaaa agatttaagg gcagcgtcta aataattggc
      961 agtagcaaag taaccattga tcgtttcatc gtctgttttg gctaaaggaa aaccttcttc
     1021 actactttcg ccttttagac tagtataagg atagtgatta ctcacagtga taaacttggt
     1081 ataaaaaggt tgttgcatct gttcaagata ttttatggaa tccttaaaca tgtacttatc
     1141 atttaaccca tattgaaaag agttcttact attttgttta gagaagtagc tagaatcaaa
     1201 aaaataatta tagccccatt gtttataagc attattgcga ttccagaaag ttccaacgtt
     1261 accatgaaag acagcgctgg tatagccgcc tttttgggct aaaatacttg gagtagcaaa
     1321 ttgtgtattt tcaccaccgt agttcaccat aaaagaacca ctatttaaac caaataagga
     1381 attctccatc atggtttcag catcagaagt tttacctgct ttaacctgat gaaaaaagtt
     1441 agggaatgct aaggtagcat ttgagtgata aagcgagttg ataaaaggcg ttacctcata
     1501 ttctttatct ccttctttta gtttataatc tattaagaat tgttgaaagc tttctaaatg
     1561 aagaacaata atatttttgc cttttccaat tccaaaatac tgaggatcag gtgctgcata
     1621 atgtcctttg acataagttt taacatcaat taattcttct gcagtagctc catttcgttc
     1681 tttttgagct tgataggttt gattgccgct atagagggta aacgctggta gtcctaaagc
     1741 tctcacaata taagtatttg aaaagccacg tgttaatagt tccggacgat caatttctgc
     1801 taaaaaaaga ttaatagaaa gcaatagact agataaagcg gtgatggcaa atgctgcgcg
     1861 cttgttaaaa ggacgttggt catttttgat ttttttagtg atagataaac taattagaat
     1921 aataaaatca agaatataga taatatccca gatgcgtaaa aggtttaaag cagagtcccc
     1981 taatccagcg gagactttac tactagctag catggcactc actgtaataa agtctgaaaa
     2041 ttctcggtaa tatatagaat ttgatatcaa gagaatgtta aggataatat aaaccaccca
     2101 agaacagata taaaaggctc gggtattctt aacgtaaaga gcaaccccca aaagtaaaaa
     2161 agctagtggg attggattga taatagttag aaagacttgg tatatatttc ccaaatctag
     2221 tgaaaagtct gtatgatatg cccacagggt ctttatccag tagcaaaaga gtagagtaat
     2281 tataaaaccc aatcttgtgt tgataaaacc tgtgataagt gttttaaatt tcttcacagt
     2341 agcaacttcc ttatcgtttt ttcctaaaga tgtcatctcc aaataaaatc tcagattaaa
     2401 ttataccaaa aatgtgaagc taatgcttgt tgtaagttca aatttagtag gattttttat
     2461 ca
//
LOCUS       DAUNLR010000092         2411 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUNLR010000092 DAUNLR010000000
VERSION     DAUNLR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2411
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.092"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            38..565
                     /locus_tag="VLL59_001712"
     CDS             38..565
                     /locus_tag="VLL59_001712"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509811.1"
                     /translation="MKTKSKRFSNLATLCLALLGTTLLTTQPVKAEGVPASSDSGEQL
                     GSPALTENQRERKLIEEQYFGKWAGKEDLHDPYYKGKLDGYIAGYEDGRKTDSVHPDI
                     KLGDGEHGEKIQEPNVTPYFYNDEDKKQEQEYKNGYGENYGLGYYDGWSNVNPIRSTL
                     EWLWREVSYWFSNFI"
     gene            877..1128
                     /locus_tag="VLL59_001713"
     CDS             877..1128
                     /locus_tag="VLL59_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509812.1"
                     /translation="MPEKKVLPVLSMVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLAGLILAALAVAVVAYAYYDPTVIPY"
     gene            complement(1223..1897)
                     /locus_tag="VLL59_001714"
     CDS             complement(1223..1897)
                     /locus_tag="VLL59_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509813.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRAEDAIKWKLDPETSQNSPIVVNI
                     DNGNKLRFTLPTGWSVSFKRKKDHYNPLEVNNKPVEVNNKPVSETKNRNTSPRIVDYG
                     KNGNPILAIYNDNQGSSGLPITVTVDKPNEGDELTLLYRADDGFFGGFTKLKDSKTLE
                     KEKKEKERQLAEEKQIEEERKHVEQKQLEENMLKQIREEDHKPWHQRLSESIQDQWWN
                     FKGLFQ"
BASE COUNT          659 a          448 c          466 g          838 t
ORIGIN      
        1 taaaaatata tcaaaaataa tgaaatggag tgattttatg aaaacaaaat caaaacgttt
       61 ttcaaaccta gcaacccttt gcttggccct actaggaaca actttgctaa cgacacagcc
      121 cgtaaaggcg gagggagtgc ctgctagttc tgatagtggg gaacagttgg gcagtcctgc
      181 gttaacggag aatcagcgag aaagaaaact tattgaagaa cagtactttg gaaaatgggc
      241 aggaaaagag gacttacatg atccttacta taaaggaaag ctagatggtt atattgctgg
      301 ctacgaagat ggtagaaaaa cagactctgt tcaccctgat ataaagcttg gagatggaga
      361 gcatggagag aaaattcagg agcctaatgt tactccttat ttctataatg atgaggataa
      421 aaaacaagaa caagagtata aaaacggtta tggtgagaac tatgggcttg gttactacga
      481 tggttggtct aatgtcaacc caattcgatc gactttagaa tggttatggc gtgaggtatc
      541 ttattggttc tcaaatttta tttaatctaa gcaagatgct tttgaaatgg atgaagaaac
      601 taatgtgaag atcaagacct tccccatgct ccagaagttt catctaatga gcaagaacgc
      661 ggtgaagatg atagtctggt atcattgggt ttacaatggt tattgagtga gatatcctct
      721 tggttaagtg gtatttttta tagcattggt taacatcacg ctattttaaa acaattttct
      781 gctataattg ggatagtccc tttagtagtt aggccacctc tgataggggt ggcttttttg
      841 ggttttagtg acccgtgtgt tgagaaagga gcatgtatgc cagaaaagaa agtgttgccc
      901 gtcctaagca tggtggtgag ttttgtctgc ctgcttgatc atatcttctt ttttgctact
      961 tatagttatc tctacttgcc gcttgtagca agtagtctag ctcttatcgg tctggtgcaa
     1021 aacaaaggca ggcaaaaggt ttggtcgcta gcggggctca tcttagctgc tctagctgtg
     1081 gcagtagtgg cctatgccta ctatgaccca accgttatcc cctactaacc ttaacctccc
     1141 cttcgcacgc aatcaacagc acaaaaagca cccctgacag gtgctttttg tgctttagcc
     1201 aacctcatag cctcgtaaac cctcactgaa acagtccctt aaagttccac cactgatctt
     1261 ggatgctttc gcttaaccgc tgatgccaag gtttatggtc ttcttctctt atctgcttta
     1321 gcatattttc ttctagttgt ttttgctcaa cgtgctttct ctcttcctca atttgttttt
     1381 cttctgctag ttgtctttct ttctctttct tttctttttc tagtgtcttc gaatctttta
     1441 attttgtaaa tccgccaaaa aaaccatcat cggcacgata aagtagtgtt aattcgtccc
     1501 cttcatttgg tttatcgaca gttacagtga ttggtaaacc tgatgaccct tggttatcat
     1561 tataaatagc taaaatagga ttaccatttt taccataatc tactatccta ggactagtat
     1621 ttctgttttt tgtctcagat actggcttat tatttacttc tactggctta ttatttacct
     1681 ctagaggatt gtaatgatct ttttttcttt taaaagatac cgaccagcct gtaggtagtg
     1741 tgaatcgtag tttattaccg ttgtcaatgt tcacaacaat tggactattt tgagaagttt
     1801 ctggatctag cttccacttg attgcatcct ccgctctgac gctactagtt accccgatgg
     1861 caaagagtgc cagtagcaag gttaatgtct ttttcatttt tttctctcct tttgctcatt
     1921 ttttaagaca agggttatta taccaattct tgcgctaaaa agatagggat tgattggctg
     1981 aggcgatcgg agaagtccta gatttctctg agtggctgcc actcacttaa tgtttcacta
     2041 ttttattggg atatgctaat acttcaagat atctttatat cgtctatagt caagagtcta
     2101 tttgacactt tatctctatt aaataatttg cacactctgt taagtgctct ttttggtcgt
     2161 atcctttttt aaagttgttt tatgtcagtt gaaaacgacg tttcttgagt aacctaactt
     2221 acctgatatc ttgtatcgtg atacgttatt tatcaatatt atgaaataga acaacgatat
     2281 taggcattct tttcgattaa cttcgaatag tttaataaat gtttatcatc tgcaattttc
     2341 agcataattt aaagaaatac gactgtatct tgataggtac tgttttttga tgtctttaac
     2401 aatatattct c
//
LOCUS       DAUNLR010000093         2387 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUNLR010000093 DAUNLR010000000
VERSION     DAUNLR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2387
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.093"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            192..926
                     /locus_tag="VLL59_001715"
     CDS             192..926
                     /locus_tag="VLL59_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HER6509814.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIKGLDYKWSENTSIKEALNE"
     gene            919..1905
                     /locus_tag="VLL59_001716"
     CDS             919..1905
                     /locus_tag="VLL59_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HER6509815.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNRHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1915..>2387
                     /locus_tag="VLL59_001717"
     CDS             1915..>2387
                     /locus_tag="VLL59_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HER6509816.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVP"
BASE COUNT          887 a          292 c          466 g          742 t
ORIGIN      
        1 tgatttagga atacattatg tagaactagg taaaggaatt atcgattata aaacaatcat
       61 tcatgaaatc catgaacatt ttatagactt aatttttagt ttagaagtac atgaaaaaga
      121 aatagacaaa aaggcagaag tagtgaggaa gtcttatctg acactaaatg agtatattaa
      181 tggaggctaa aatgaatttg agtatatttg gtttaaagaa tattccttat ttgaaagaag
      241 gggatagtat agaaaagctt attgaagaaa gcattaaaac ttcaggattt tttatcgaag
      301 acaatgatgt gctttgcata gcttctaaag ttgtatctat cgcagaaggc caggtgatgt
      361 ctttaaacga gatacaagtg agtgatgtag caaaagaaat ccacaggaat attcctcgta
      421 aagatcctag aataattgaa attatgctaa atttagtcaa tagagatctg tcacgtttag
      481 atatcaaaaa aaattacatt ggttgtcgct tggaaaatgg tttaaagttg acaagtggtg
      541 gaatcgatag aaaatcagta gatgaagtat ttcttttacc taataatccg gatgcttctg
      601 caaaaagaat ttcggaatat cttaaaaaat cacttggaaa aaatgttgca gttgttataa
      661 cagatagtga tggtagagag gataaaagag gtgctactca agtagcaatt ggtatttatg
      721 gtattcatcc tttgagaaaa acagaagtaa tagattcaca aggagagaca ataaaattcc
      781 aagaagagac tttgtgtgat atgattgcag cttgtgctgg cttagtaatg gggcaacgtg
      841 gaactggaat tccagctgtc ctcattaagg gcttggatta taaatggtct gaaaatacta
      901 gtattaagga agcgttaaat gagtagaaat caggactgta agaatattct aatcattggt
      961 tttggaaaaa ttgggaaaat taaagcgtac aagtggctat cacgcggata tgaggtatat
     1021 gtcaaagatt tgaaattctc cagcatgaaa taccttaata caaatagtga tgtgttggat
     1081 gatttatcac gacaatattt tactattgag atttgtactc cgacaaatcg ccaccttacg
     1141 ctattgaaaa ccgttataac aaggtatgtc tattcttata ttagcattga aaaaccactg
     1201 tgtaacaggt tagaagattt agaagaaatg aagtcgctag tagaaagtca cccacatcta
     1261 gcaaaaaaaa tttttgccag tgaacaatac ttcttttcga aaattttgga aaaactgtta
     1321 caagtagatt gtttctctct agataaaatc aaggaaataa cagttaattt ttctaaagat
     1381 aggattgagg ataacgagaa tgggagattt ttagataaag agatattggg ctatggaata
     1441 gagattcctc atatcattgc tgtcatttct tatttaggaa tttcattaga ggaattcaaa
     1501 aaaggaatct ttgtgaatgc tatttatata aaagacttag agaaacacga ttattcaata
     1561 gaaatattat cttgtattaa tcaaacagtg attaaaatta ttagtaattt gggaagtttt
     1621 gcaataagag agggcaagat tgaaggaggt gatgctaaaa cagtaagaag agttaccatt
     1681 gatgacaaaa caatactatt tgatccacat cctaaactcg agaggtataa gagtgaattg
     1741 gtgactggga caaatacgtt tcaaatacac gatgatatga tggacacgta tatcagtttg
     1801 ttagaaggaa atgctattcc tgaagattgc tatatcaata atgcaattga gataacaaaa
     1861 ttattaatta acttatattc agaatgtgaa aaaatttatt tatgaggtgt aactatggat
     1921 ttaaaaatta caaacggctt ttatgaccca agtcatttat catacgaagt agtagaacgc
     1981 aaaggcttag gtcaccctga taccttagca gatggaattg ctgagcaaat tgaaattgat
     2041 tactcacttt attgtttgga caagtttggt gttattccac atcataattt tgataagatt
     2101 attatccgag ggggacattc agttcaggat tttggtggaa gtgactttat tgaaccaatt
     2161 aaaattattt ttctaggtag ggcgagcaaa aaatgtttta atagttcaat tccacttttt
     2221 aaaattcaga aaaaggctgc aactaaatat ttaaatagaa ttttacctaa tttagatgtt
     2281 gaaaattatg tagaatttga gacattgacc tcagatttta ctacaaaaac taattggttc
     2341 tcgcctgaag caatagaaga tttaccggag tatctagatg taccaaa
//
LOCUS       DAUNLR010000094         2371 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUNLR010000094 DAUNLR010000000
VERSION     DAUNLR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2371
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.094"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            24..1865
                     /gene="typA"
                     /locus_tag="VLL59_001718"
     CDS             24..1865
                     /gene="typA"
                     /locus_tag="VLL59_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HER6509817.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            1987..2238
                     /locus_tag="VLL59_001719"
     CDS             1987..2238
                     /locus_tag="VLL59_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HER6509818.1"
                     /translation="MFYLIMAVLIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
BASE COUNT          724 a          422 c          510 g          715 t
ORIGIN      
        1 aatatattta cttagaggaa caaatgacta acttaagaaa cgatatccgt aacgtagcga
       61 ttattgccca cgttgaccac ggaaaaacaa cacttgttga tgaattatta aaacaatccc
      121 atactcttga tgagcgtaaa gagcttcaag agcgtgccat ggattccaat gaccttgaaa
      181 aagaacgtgg gattacaatc cttgcgaaaa atacggcagt agcctataac gatgttcgta
      241 ttaacatcat ggatacccca ggacacgcgg acttcggtgg tgaagttgaa cgtatcatga
      301 aaatggttga cggggttgtt cttgttgtgg atgcctacga aggaacaatg ccccagacgc
      361 gtttcgtatt gaaaaaagca cttgagcaaa accttatccc gatcgttgtg gtgaacaaga
      421 ttgacaaacc ttcagctcgt ccagcagaag ttgtagatga agtgcttgaa ttattcatcg
      481 aacttggtgc cgatgatgag caattggaat tcccagttgt ttacgcatca gctattaatg
      541 gaacatcatc attatcagat gaccctgctg accaagagca tactatggca ccgatctttg
      601 atacgattat tgatcatatt ccagcgccag ttgataattc agatgagcct ttgcaattcc
      661 aagtgtcact tttggactac aacgatttcg taggtcgtat cggtatcggt cgtgttttcc
      721 gtggtactgt taaagtgggt gaccaagtaa ctctttcaaa acttgatggt accactaaaa
      781 acttccgtgt tacaaaactg tttggtttct tcggtttgga acgtcgtgaa attcaagaag
      841 ctaaagcagg tgacttgatt gctgtttcag gtatggaaga tatctttgtt ggagaaacca
      901 ttacaccaac tgactgtgtg gaagctctgc caattcttcg tattgatgag ccaacacttc
      961 agatgacttt cttggtcaat aactctcctt ttgcaggtcg tgaaggtaaa tggatcacgt
     1021 cacgtaaggt tgaagaacgt cttttagcag aattgcaaac agacgtgtca cttcgtgttg
     1081 acccaacaga ttcgccagat aaatggactg tttcagggcg tggagaattg catttatcta
     1141 tcctcattga aaccatgcgc cgtgaaggct atgaacttca agtatcacgt ccagaagtta
     1201 tcatcaaaga aattgatggt gtcaaatgtg aaccgtttga gcgtgttcaa attgatacac
     1261 cagaagaata tcagggtgca atcatccagt ctctttcaga acgtaaaggg gatatgcttg
     1321 atatgcagat ggttggtaat ggtcaaacgc gtttgatttt cttgattcct gcacgtggtt
     1381 tgattggtta ttcaacagag tttctttcaa tgacacgtgg atatggtatc atgaatcata
     1441 cttttgatca gtatctaccg gttgttcaag gagaaatcgg tggccgtcat cgtggtgcct
     1501 tggtttctat tgaaaatggg aaagcaacga catattcaat catgcgtatt gaagaacgtg
     1561 gaactatctt tgtcaaccca ggtacagaag tttacgaagg gatgattgtt ggtgaaaact
     1621 cacgtgataa cgaccttggt gttaacatta caacagctaa gcaaatgaca aatgtccgtt
     1681 cagcgactaa agatcaaact gcagttatca agacgcctcg tatcctaacg cttgaagaat
     1741 cattagagtt cttgaatgac gacgaataca tggaagtaac gccagaatct atccgcttgc
     1801 gtaaacaaat cttgaataaa gctgcgcgtg ataaagctaa taaaaagaaa aaatcagccg
     1861 aatagctttt gaagttaaac taactaaata aaatagcaaa aagatattta agaaaagtca
     1921 ttttttaaag gtctttttgc gtttacaagt tcctatggaa tataaaccaa aataaaggag
     1981 gacggaatgt tttaccttat tatggctgtc ttgattatat cttattatct atacatggct
     2041 cctaaaagtg tccgtaacac ccttgggatg attggtttag ttggcttggt tgctctgctt
     2101 attgttttag cgggcttgag ttttatcaaa atcatgcaaa cccctcctga attttttatt
     2161 gggatgggaa tggtggcatt gggctatttt gctttaaaag atgtgcgtaa aatgaccaaa
     2221 aaaccgagag ttaaataaaa atacttaaag attgatgatt ttggttttta tacgataaaa
     2281 ggactgattt gttttagaca atatcagtcc ttttttaata gttcattttt tctgaaagaa
     2341 agcttttagc cgattttcat tgagtgtgca a
//
LOCUS       DAUNLR010000095         2289 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUNLR010000095 DAUNLR010000000
VERSION     DAUNLR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2289
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.095"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..556
                     /locus_tag="VLL59_001720"
     CDS             <1..556
                     /locus_tag="VLL59_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HER6509819.1"
                     /translation="FFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARLLS
                     FTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNGTN
                     EKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQNDLK
                     NIQYDVTIGKGYLLKHKTFFKISR"
     gene            735..1430
                     /locus_tag="VLL59_001721"
     CDS             735..1430
                     /locus_tag="VLL59_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HER6509820.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            1432..1773
                     /locus_tag="VLL59_001722"
     CDS             1432..1773
                     /locus_tag="VLL59_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HER6509821.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            1766..>2289
                     /locus_tag="VLL59_001723"
     CDS             1766..>2289
                     /locus_tag="VLL59_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HER6509822.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVC"
BASE COUNT          759 a          339 c          400 g          791 t
ORIGIN      
        1 atttttctca gttattacaa tgcaaaatca tattccttgg tcatccgatt atcctgaaga
       61 aattgttgct gaaggaaaaa atttcacgga agaagaaaat cacaacctaa caagttatgc
      121 tcggttatta tcgtttactg ataaggaaac aagagcattt ttagaaaaat taacacaaat
      181 taacaagcct atcacagtgg tgttttacgg agatcattta cccggtttat atcctgatag
      241 tgcttttaac aagcatattg aaaataaata ccttactgat tattttattt ggagtaatgg
      301 tactaacgag aaaaaaaatc atccgcttat caactcaagt gattttactg cagctttatt
      361 tgagcatact gattcaaaag tatcacctta ctatgctttg ttaacagagg tactgaataa
      421 agctagtgtc gataaatcac cagatagtcc tgaagttaaa gctattcaga atgatttaaa
      481 aaatatccaa tacgatgtga ctataggaaa aggttacctt ttgaaacaca aaactttttt
      541 taagatatca cgttaagaaa aatgctaggc tgtccgagta tagacgagca tcaaggtttg
      601 gtaatttgct caaatgattg tcaacagagt gtctaggacc aggtttaaaa gattataatt
      661 cttaaggtct tattcgttta taaaaaatga atactctttt aaaatcttaa ttgaaatgaa
      721 taggagaagt tttcgtgaaa aagttaatca ttattcctgc ttacaatgaa agcagtaata
      781 ttgtcaatac tatacgtact attgaatcag atgccccgga ttttgactat atcattattg
      841 atgattgctc aacggataat acgttagcaa tatgtcaaaa acaggggttc aatgtgattt
      901 ctttgcccat taacctggga attggcggtg cggtgcaaac tggctatcgt tatgcacaaa
      961 gatgtggata tgatgttgca gttcaagtag atggagatgg tcagcacaat ccatgctatt
     1021 tggaaaaaat ggttgaggta ttagttcaat cttcagtaaa tatggtaatt ggatcacgat
     1081 ttatcacaaa agaagggttt cagtcatcat ttgctcgacg tatcggtata aagtatttta
     1141 cttggcttat tgcgctacta acaggaaaaa aaataacaga tgcaacgtca ggtctaaggt
     1201 taattgatcg ttcattgatt gaacgttttg ctaatcatta tccagatgat tatcctgaac
     1261 ctgaaacagt tgttgatgta ttggttagtc attttaaagt gaaagaaatt cctgttgtaa
     1321 tgaatgagcg acaaggcggt gtgtcatcta tctcgttgac gaaatcggtc tattatatga
     1381 ttaaagtgac tttagctatt ttagttgtta gattgaaagg aaatcgttaa aatgacggta
     1441 acagccagtt tatttataag ttttattgta ttaacctttg ttttcttttt gattaactta
     1501 atcaaaaaag acaaactagc gattaagtac tctttattgt ggtttatttt agctttatta
     1561 attttactat ttacgtggtt acctaacata ttaaataaaa tgtctcactt cctgggtatt
     1621 cattcaccaa ccaatatgtt attcttttta ggtttttgtt tgagtttagc tattattttt
     1681 tcactgacta ataatatctc acttcaaaat gataaagtaa aacgtctgac ccaagaagtg
     1741 gcccttatga aaaaagagaa aaccaatgat taatccttca aaacaaaacc aaacgatttt
     1801 tttatggaat atgttaggaa gtttatcaac agctgtaata tcagttatat tacttatggt
     1861 ggttactagg ttactaactt cggctgattc agatatttac gcctttgcct attcttttgc
     1921 taatatgatg gtagttgttg gactttttca ggttcgtaat tatcaagcaa cagatattaa
     1981 tgaaaaatat tcctttagtc agtacttagt ggcaagactg atgacttgtt tattaatgtt
     2041 agccataaca gtaatttatt taacgttaac taagacagat agctacaaga gtacaattgt
     2101 ctttctagtc tgtttctata gatcgacaga tgctttttcg gatttatatc agggaatgtt
     2161 ccaacaacat gaacggctgg atattgcagg taaatcgcta gcctacagaa atactcttat
     2221 ttttatggtg tacacagcaa taatattata ttccaaaaat cttactttag cattagtagc
     2281 tgtctgtat
//
LOCUS       DAUNLR010000096         2225 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUNLR010000096 DAUNLR010000000
VERSION     DAUNLR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.096"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            226..1481
                     /locus_tag="VLL59_001724"
                     /pseudo
     CDS             226..1481
                     /locus_tag="VLL59_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1780..1915)
                     /locus_tag="VLL59_001725"
                     /pseudo
     CDS             complement(1780..1915)
                     /locus_tag="VLL59_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT          754 a          505 c          345 g          621 t
ORIGIN      
        1 caagcccagc cagcgaacac ttgcttttgt tttatacaaa acctacaatg gctagactac
       61 ttgctataaa cggcaagtag agataactat aagtagcaaa aaaagtctta taatatctgt
      121 agtgggtaac tcccctacag atattataag actttttgga tgtacacaaa aaatcccata
      181 tgacttataa tgcaaagcga ccaaaccatc attagaaaga atcatatgag acaactctat
      241 catactacag aattgattgg aattaaagat aaacacatca ccttgaacaa ggtttttcaa
      301 cgcgagacac ctatcgaagt cttcgccaca cttgactatc ccccacctaa gtgtaaacac
      361 tgtaaaggag ttcagattaa atacgactcc cagaaacatt ctaaaatccc ctttatcgaa
      421 attggtggtt tccctagtct cattcgttta aaaaggagaa gatctcaatg caagtcctgt
      481 cgaaaagtgg ctgtagcgga aacaagtctg gttcaaaaaa aactgtcaga tctctgagca
      541 cctcagacaa aaagtagcac aaaccttggt taatcgaggc gctctcacta acatcgctca
      601 acagtcggct agatcatcct ctaccgtcta ccgaaaactc aaccagtttg taatcaagga
      661 agacttctct aaactacccg aggtgttgtc ttgggatgga ttttcctatc aaaagggcga
      721 actcgccttt atcgctcaag attttgagtc caaaaaatca tctccatact ggacaaccgg
      781 cgacaaacaa ccattcgaaa tcacttcttt agatactcta aagaggctag aaacagtgtc
      841 aaaatcgtta ccgttgatat gtcaggaagc tatatttcgc tcattaaaaa gctatttcct
      901 caagctaaca tcgtcctaga tcgtttccat attgttcagc acatgaacag agcgctcagt
      961 caaacccgga ttcacatcat gaagcaatat ggacaaaaag tctctggaat acagagttct
     1021 taaatactac tgtcaactca ttcaaaaggt agccgaaaac tctcgctcaa cgccttctac
     1081 tctagaactt ttagggaaac gctaactcct aaacaatgtc tcaataaact atttaatctc
     1141 gttcctgaat taaaagatta ctatgacctt tatcagttac tcctttttca cttacaagag
     1201 aagaatactg agcatttttt gacttaattc aaaaggtgtt acttctgctc aatcacacct
     1261 ttaaaacggc tttgaacacc ctgatgcgat acaaaaacta tgtcactaat gccattgagc
     1321 ttccttgttc aaacgccaaa ctagaagcaa ccaatagact catcaaacac atcaaacgca
     1381 atgcttttgg ctttcggaac tttgataact ttaaaaaacg catttacctc gctttgaaca
     1441 taacaaaaga gaagacgagt ctcgtctcct cacgtgttta gctataagtc acccactaca
     1501 gttgacaaag agcccaaaaa agaagatatg atcaagcagg cagacaaaac tcaccatcat
     1561 gcttaggacg ggcaacactt tcttttctgg catacatgct cctttctcaa cacacgggtc
     1621 actaaaaccc aaaaaagcca cccctatcag aggtggcctg actactaaag ggactatccc
     1681 aattatagca gattagtgtg agaattgctt gaactaagca aagtatcctc aagcttttca
     1741 atacttcaca ataactacat taagacaaca aatgtgtcat ttactgagag ttttactcac
     1801 atcaatccca aatactgcat acctgataat accccttttg tcttgaatga ttccttattt
     1861 tagtgatttc attttcaata cacgacgtca agcgtcctac atactttgat aaaattctac
     1921 ctaaaagagg tgtcttgtca gttttgttta cgacatcaag cgacaaaata ctttgcgact
     1981 taacaagaca cttctacttt aacgtaaaga aaaagtagtg aatactctct cgtcggaggt
     2041 ttcctcacta ctaatcttag tatgtttatt ttgccctaaa ccactcttct atattatttt
     2101 ttaaaaaata atatagaagg caaaaagaga aacaagtcgc tcgactagtc agtcttctgt
     2161 ctgagacaag atcttaccgt tactttttac attatgacta agaaggcatt atctcagact
     2221 cttga
//
LOCUS       DAUNLR010000097         2214 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUNLR010000097 DAUNLR010000000
VERSION     DAUNLR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2214
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.097"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            6..347
                     /locus_tag="VLL59_001726"
     CDS             6..347
                     /locus_tag="VLL59_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509823.1"
                     /translation="MTFERIKELAKKQGLSINSLEEKMGYSRNTIYALKRNKPGSEKL
                     QEIADYFHVSTDYLLGRTDNPAIAKDNQEYTSEDLRKMAENAKTFDGKPLTESDIEAI
                     QNIIEIYLKGR"
     gene            351..731
                     /locus_tag="VLL59_001727"
     CDS             351..731
                     /locus_tag="VLL59_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HER6509824.1"
                     /translation="MTIEEILDFHNVELAYFDNELWPRPGIYIDEIKVVFVNRALSDE
                     SKKKVIFHELGHIEHDSGQYQRRHEEFELQANRHMIRCLLEDEFDKVEDKHEFNYLSF
                     MQRHNLKTTTDEVMVIDEYYTLIG"
     gene            743..1009
                     /locus_tag="VLL59_001728"
     CDS             743..1009
                     /locus_tag="VLL59_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HER6509825.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            1138..>2214
                     /locus_tag="VLL59_001729"
     CDS             1138..>2214
                     /locus_tag="VLL59_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HER6509826.1"
                     /translation="MRKVAIYSRVSTINQAEEGYSIQGQIEALTKYCEAMEWKIYKNY
                     SDAGFSGGKLERPAITELIEDGKNNKFDTILVYKLDRLSRNVKDTLYLVKDVFTANNI
                     HFVSLKENIDTSSAMGNLFLTLLSAIAEFEREQIKERMQFGVMNRAKSGKTTAWKTPP
                     YGYRYNKDEKTLSVNELEAANVRQMFDMIISGCSIMSITNYARDNFVGNTWTHVKVKR
                     ILENETYKGLVKYREQTFSGDHQAIIDEKTYNKAQIALAHRTDTKTNTRPFQGKYMLS
                     HIAKCGYCGAPLKVCTGRAKNDGTRRQTYVCVNKTESLARRSVNNYNNQKICNTGRYE
                     KKHIEKYVIDVLYKLQHDKEYLKKI"
BASE COUNT          863 a          335 c          420 g          596 t
ORIGIN      
        1 tgtttataac atttgaaagg ataaaagaac ttgctaaaaa acaaggtctt tcaataaatt
       61 ctctagaaga aaagatgggg tatagtcgaa ataccatcta tgctttaaaa cgaaacaagc
      121 caggttctga aaaattacaa gagattgcag actatttcca cgtctcaaca gattacttgc
      181 ttggtcgcac tgataaccct gcaattgcaa aagataacca agaatacact tctgaagatc
      241 tacgaaaaat ggccgaaaac gccaaaacgt tcgatggtaa gccgcttact gaatcagata
      301 ttgaagcaat acaaaatatt attgaaattt acttgaaggg aagatagtct atgactattg
      361 aggagatttt agacttccat aatgtagaat tagcttattt cgataatgaa ctatggccac
      421 gtccaggaat ctatattgat gaaataaaag ttgtcttcgt taatagagca ttatccgatg
      481 agtcaaaaaa gaaagttatt tttcatgaac taggacatat tgaacatgat tctggccaat
      541 atcaaaggcg tcatgaagaa tttgaattgc aggcaaatag acatatgatc aggtgtttgc
      601 ttgaagatga atttgacaaa gtagaagaca aacatgagtt taactacttg tcttttatgc
      661 aaagacataa tttaaagacc acgaccgatg aagtcatggt tattgatgag tattatactt
      721 taataggtta aaggagatta tcatgggatt tttggacaat gtaaaagaag ctagtactgt
      781 ttcaactgct tctggcgaaa attatgaata tgttgtgcta caagttacac taaaagaaaa
      841 gcttatagga acaggctcag gaaatttaac tgaacttgaa aatgttatta ataagcaagc
      901 aaaaaaagga tatcgcctac acactattac cacatcaaat ggtggcagta aaggatttgg
      961 tggcggagat agaatacaag ctacaatggt atttgagaaa atcaagtaaa ataaaaaaag
     1021 ccccacgctc tcaaagtttg gcgactctga gcgtgaggcg aatctagtat agtaaaaacc
     1081 tgctttaagt aggtctcttt actgtactca ttttaacaaa aaatgaggta aaaaacaatg
     1141 agaaaagtag ctatttactc tagagtatca acaataaatc aagccgaaga aggatattcc
     1201 attcaaggac agattgaagc tttaacaaag tattgtgagg caatggaatg gaaaatttac
     1261 aaaaactact ctgatgcagg tttttcaggc ggtaaacttg aacgaccggc aataacagaa
     1321 ttgattgaag acggtaaaaa caataaattt gatactattt tagtctataa actagacagg
     1381 ctatcaagaa atgtaaaaga cacactttac ttagtcaaag atgtatttac tgctaacaat
     1441 atccattttg tcagcttaaa agaaaatatc gacacttctt cagcaatggg aaatctcttt
     1501 ctcactctct tgtcagctat tgcagagttt gaaagagaac agattaaaga gcgaatgcag
     1561 tttggtgtta tgaatagagc aaaatctgga aaaacaacgg cttggaaaac accaccttat
     1621 ggatatagat acaacaaaga cgaaaaaaca ttgtcggtca acgagttaga ggctgctaat
     1681 gtcaggcaga tgtttgacat gataatctct ggctgctcaa tcatgtcaat tacaaattac
     1741 gcgagagaca atttcgtcgg gaatacgtgg acacatgtaa aagtaaaaag aatattagaa
     1801 aacgaaacat ataaaggatt agtgaagtat agggaacaaa ctttctcagg tgatcatcaa
     1861 gccattatcg acgaaaaaac atataataaa gcgcaaatag ctttagcaca taggacagat
     1921 acgaaaacaa atactagacc ttttcaaggg aaatatatgc tttctcacat agcaaaatgc
     1981 ggttattgtg gtgccccttt aaaagtatgc acaggaagag ctaagaacga tggtacgaga
     2041 aggcaaactt acgtttgtgt taataaaaca gaaagtttgg ctagacgaag tgttaataat
     2101 tataataacc aaaagatttg taacactggt cgatatgaaa aaaaacacat cgaaaaatat
     2161 gttattgatg ttctttataa acttcaacac gataaagaat atcttaaaaa aata
//
LOCUS       DAUNLR010000098         1933 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUNLR010000098 DAUNLR010000000
VERSION     DAUNLR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.098"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(97..665)
                     /locus_tag="VLL59_001730"
                     /pseudo
     CDS             complement(97..665)
                     /locus_tag="VLL59_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014572446.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            983..1210
                     /locus_tag="VLL59_001731"
     CDS             983..1210
                     /locus_tag="VLL59_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HER6509827.1"
                     /translation="MEIKKLETFHQMTIEKLAKAEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITFWAGVTGATGGF"
     gene            1223..1423
                     /locus_tag="VLL59_001732"
     CDS             1223..1423
                     /locus_tag="VLL59_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HER6509828.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            1718..1912
                     /locus_tag="VLL59_001733"
     CDS             1718..1912
                     /locus_tag="VLL59_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HER6509829.1"
                     /translation="MEVLKNGLAIINGGGKDGANIFLTGMAGAAQGVTVCAQTGVFIP
                     WQGYILCGAAGAATNIIWPH"
BASE COUNT          617 a          295 c          396 g          625 t
ORIGIN      
        1 gtgtcaaaat atactccgaa tcctttatga atacgagctc cgaacttaat attatagtct
       61 tcgaaaatac ttacaagaca tcgttctaag gcttcttcat ttggaaaaac caccctcctt
      121 cttgctttgt cgcttgattt ctttattgag tgattcaatc aagtttgtag agtaaatact
      181 agaccaaatg taatgtggaa attgatagaa agttaggaga ttttccgttg tttcaagtga
      241 tgtcataacc tttttgtaac gaggcttcca ctcagaaaca agtggtgacc atacatgcgc
      301 tcaataatgt cactgatttc gcgtgtcgta acgccagtct gatagagttt gatcaccatc
      361 tcttccaagt ggtcatctcg tctagcataa gatggtaata aaactggtga aaactcgccg
      421 tttcgatctc ttgggatgat taaattgact aagccatact ttgtttcaaa ctgacgagaa
      481 taagtcccat tacggctatt acctgtgttg taaccttctt tttcataagg ttcataacca
      541 agaaaagctg atagttcaac ttgcaagagg tcattcatag ctatttctaa agaggagcga
      601 aaaaattcat caatatcttg tttttgtgct aggaagttaa gtaattctgt ggtaaactga
      661 gtcatgggaa taaatctctt tctagtaagt ttcgcaactc tactatacag gatttattcc
      721 tttttgtgtg tttacacaag atattttaca ctaccatcaa aaatcttaaa agatatttat
      781 aaaagcatga atggtatcat ttaaacttct taattaatta actattgtca cagcgtaagt
      841 gtagagagga taaaaagaca tttcatgatg aaaaaacagc cttttaagat tttgaagcca
      901 tgatactgtt ctttatgata ttctgtacta gtcgaggttg caacgagaca aatttaagaa
      961 ttatgaaaag gagttattcg atatggagat aaagaaactg gaaacatttc atcaaatgac
     1021 tatagaaaag cttgccaagg ctgagggtgg taagaataat tggcaggcaa atgtcagtgg
     1081 ggttatcgct gcaggtagtg ctggagctgc tataggtttt ccagtctgcg gtgtagcctg
     1141 tggttatatt ggagctaaaa cagctattac tttttgggct ggtgtaacag gagctacagg
     1201 cggcttctag aggaaagaaa ggatgacaac aatgaaggaa ttaacaatta atgacatggc
     1261 tagtataagt ggaggaaacg ctccaggaga tgctgtaatt ggtggtcttg gaggcttagc
     1321 ttctggattg aaattttgta aactgccaca tccagtattg acaggtggat gtgttgtagg
     1381 atttacagtt ggtggagcat atttgggata tacagcaaat taaatgatct atacgatttt
     1441 tattattatg catgcgtcta taatgttttt aatgattgtt gatgccattc ataaaaaaaa
     1501 tgttgataaa tctataccat atttagtgtt tttaattttc aatcaattat ccctttcgga
     1561 aaaatcggta aacatgttat ctatcgtagc tttggtagcg tcattatttg tttttatcga
     1621 taaaagaaaa tagtgattat gccaatgaat ttagatatca ctcttagctt tttaaaatac
     1681 aaaagagtga aattaaaatg aaaaagactt caaaaatatg gaagtgctaa aaaatggtct
     1741 ggctatcata aatggaggcg gaaaagacgg agcaaatatc tttttgacag ggatggcagg
     1801 tgctgcgcag ggagtgacag tttgtgctca aacaggcgta tttatccctt ggcaaggtta
     1861 tattttgtgt ggagcagctg gtgctgctac aaatattatc tggcctcact aaatatataa
     1921 atgactatct atc
//
LOCUS       DAUNLR010000099         1910 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUNLR010000099 DAUNLR010000000
VERSION     DAUNLR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1910
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.099"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..472)
                     /locus_tag="VLL59_001734"
     CDS             complement(<1..472)
                     /locus_tag="VLL59_001734"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509830.1"
                     /translation="MLKKKKNILFYLCLALLGVAVLASNPVKAEENGFEKERGTSFQT
                     PAQPLKEILQGDESETKRFPEGYDPEDPQDVGYYEGWEAGSNAPWWTLSPTIDEDRIP
                     NPKREDWLNDQSDLTSYKEGYATGFYGGWYSNHDMVGFVQNTFYWLWNQLNNFLG"
     gene            complement(1126..1542)
                     /locus_tag="VLL59_001735"
     CDS             complement(1126..1542)
                     /locus_tag="VLL59_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509831.1"
                     /translation="MKTKSKRFSNLATLCLALLGTTLLMAHPVKAEGVTQERNRVTHT
                     TGGTDGNESLKQWHRGYDEGYEKGLSGSDRSERGDIDVPKDIDSQYGDDYKDGYEGGF
                     EDGRRKAKPIETFLEDVWEFFRDIFKGWFGSDDDSQ"
BASE COUNT          554 a          436 c          297 g          623 t
ORIGIN      
        1 ttcccaaaaa gttatttaac tgattccata accaataaaa agtattttgt acaaacccta
       61 ccatgtcatg attagaatac caaccaccgt aaaatccagt cgcatatcct tccttataac
      121 tcgtcaaatc agactgatcg ttaagccaat cttctctttt aggatttggt atcctatctt
      181 catctattgt agggctaagc gtccaccacg gtgcatttga accagcttcc cagccctcgt
      241 agtaccctac atcttgagga tcttcgggat catacccttc tggaaacctt ttagtttcac
      301 tctcatctcc ttgcaatatt tcttttaagg gttgagcagg tgtttgaaaa ctagttcctc
      361 tttccttctc aaatccattt tcctccgctt ttacaggatt actagctaac acagctacac
      421 caagtagtgc caaacataaa taaaataaga tattcttttt ctttttcaac aataataact
      481 ccatttcatc attttgatat agttttattt tactactcgc attctttcat ttcaagttca
      541 tgtttttatc attttaaaca tcaaatgatt agaaaatcat ggcaatctct cttatagttc
      601 aacaaatctg ttcatcagcc ttttttaagc ttaggagctg tttttgaaag cgtttgagat
      661 tttgtgttag accttactag caactacagt gaaagcgtgg acatttgcgt ctattttaat
      721 agggaatagc tgtcggttca gattatactg ttactgctac tgctactgct actacaagcc
      781 cagccagcga acacttgctt ttgttttata caagacctac agtggctaga ctactcgcta
      841 caaaacaagt agaggtagct attaagtagc aaaagcaagc agcaacacaa ggctcaccat
      901 catacttagg acgggcaaca ctttcttttc tggcataaaa gctcctttct caacacacgg
      961 gtcactaaac ccccaaaaaa aaccacccct atcagaggtg gcgtgactac taaagggact
     1021 atcccaatta tagcagatta gtatgagaat tgcttgagct aaggaaagta tcctcaagct
     1081 cttcaataag ttacaataac taaattaaga caacaaatgt gtcatttact gagagtcatc
     1141 gtcgctgcca aaccagcctt taaaaatatc tctgaagaat tcccatacat cttctaagaa
     1201 tgtctcgatt ggtttagctt tacgtctgcc atcttcaaat cccccctcat aaccatcttt
     1261 atagtcatca ccgtattgcg aatcaatatc tttaggaaca tcaatatcgc ctcgttcgga
     1321 tctatcagat ccgcttaatc ccttctcata tccctcatca taacccctat gccattgttt
     1381 cagggactca ttaccatctg taccacctgt ggtatgagtg actctatttc tttcctgagt
     1441 tactccctcc gcctttacgg gatgtgccat tagcaaagtt gttcctagta gggccaagca
     1501 aagggttgct aggtttgaaa agcgttttga ttttgttttc ataaaatcac tccatttcat
     1561 tatttttgat gtagttatag tttactactc gcattctttc atttcaagtt catgttttta
     1621 tcattttaaa catcaaacga ttagaaaatc atggcaatct cccttaagct caacaaatct
     1681 gttaaacagc cttttttaag cttaggagtt gtttttgaaa gcgtttgaga ttttgtgtta
     1741 gtccgtaata gccaccacag tgaaagcgtg gatatttgcg tcaatttaat aaggaataac
     1801 tgtcggttca tattaggcaa cggacgggca acactttctt ttctggcata aatgctcctt
     1861 tctcaacaca cgggtcacta aaacccaaaa aggccacccc tatcagaggt
//
LOCUS       DAUNLR010000100         1802 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUNLR010000100 DAUNLR010000000
VERSION     DAUNLR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1802
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.100"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..331
                     /locus_tag="VLL59_001736"
     CDS             <1..331
                     /locus_tag="VLL59_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="biotin carboxylase"
                     /protein_id="HER6509832.1"
                     /translation="VKGFDFYNTYLKARLGLQEELNTDTNKFSGIVFFRLNPENYGKI
                     FNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERVGYVCLENKEYAVLEKEMKEI
                     LKSLSIE"
     gene            256..1275
                     /locus_tag="VLL59_001737"
     CDS             256..1275
                     /locus_tag="VLL59_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HER6509833.1"
                     /translation="MFGKQGIRCARKGDERNIKIIVNRVNSERNIKSIGICSPSYPGT
                     FHYQKRYKRGVEFLQNKGFTIVEGNLTGKEGYRGEISGGVQDRAEELNQLIPRVDVIM
                     TSIGGYNSNSVLKYIDYDLFKQKSPIFIGYSDTTALALALYKKTGCITYLSQSVISNF
                     GEFEPFNELNYFYFDFMLQSKCETLMVQIPDVWTDEWINWETYERTKKTNKNEWIIFN
                     KGEFNGTLIGGNLDTIVGIIGTEYMPKITEDTILLLEDVYTDLGRLYRNFTTLALHGI
                     FDKIGGLIISKFETIGENSDVINDIINEFVGHRKIPILLNFDCGHTHPSCLMPIGGKI
                     TLSLS"
     gene            1288..1488
                     /locus_tag="VLL59_001738"
     CDS             1288..1488
                     /locus_tag="VLL59_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509834.1"
                     /translation="MNNRESKLTGFYDVFEEEVEKINHIHNVFVEESEKFGFQQMKIA
                     MVEHRKKYLDATDVHYTKYKNI"
BASE COUNT          679 a          220 c          355 g          548 t
ORIGIN      
        1 agtcaaggga tttgattttt ataatactta tttaaaagct agactaggtt tacaagaaga
       61 gttaaataca gacactaata agttttcagg aattgtattt ttcagactca atccagagaa
      121 ttacggaaaa atatttaatg gagtgagtta cgatgcacct aaaacttcac taatatttga
      181 agaaaagata tataaaaagg aaggaactgt attgccaaat ccgattaatt ggagtaatga
      241 gagagtagga tatgtctgtt tggaaaacaa ggaatacgct gtgctagaaa aggagatgaa
      301 agaaatatta aaatcattgt caatagagta aatagtgaaa gaaacatcaa atctataggt
      361 atttgttcac cctcctatcc ggggacattt cattatcaga aacgatataa gagaggagta
      421 gaatttttac aaaataaagg atttactata gtagagggaa atttaacagg aaaagaaggt
      481 tatagagggg aaatttcagg aggagttcaa gacagagctg aagaattaaa tcaacttatt
      541 ccgcgtgtgg atgtcatcat gacttccata ggtggctaca attctaattc tgtattaaag
      601 tatatagact acgatctatt taaacagaaa tctcctatct ttattggata ttctgacaca
      661 acagctcttg ctttagcctt atataaaaag actggatgta taacttacct gtctcagagc
      721 gttatctcta attttggaga gtttgaaccg tttaatgaat taaattattt ctattttgac
      781 ttcatgcttc agagtaagtg cgaaacctta atggtacaaa taccagatgt ttggacggat
      841 gagtggataa attgggaaac ctatgaaaga accaaaaaaa caaataaaaa tgagtggatt
      901 atttttaaca aaggtgaatt taatggtact ttgatcggag gaaatctcga taccattgta
      961 ggaataatag gaactgagta tatgccaaaa ataacagagg ataccatact cttgttagaa
     1021 gatgtatata cggatctagg aagactatat aggaatttca caacgcttgc cttacatggt
     1081 atttttgata aaataggagg acttattatt tcaaaatttg aaacaatagg ggaaaatagc
     1141 gatgttatta atgatatcat taatgaattt gtagggcata gaaagattcc tattttattg
     1201 aattttgatt gtggtcatac ccatcctagc tgtttaatgc ctattggtgg taaaattacg
     1261 ttgagtttaa gctaaaagag gtggtatatg aacaatagag aaagtaaatt aacgggtttc
     1321 tatgatgttt ttgaggaaga agtagaaaaa ataaatcata ttcataatgt ttttgtagag
     1381 gagtcagaaa aatttggctt tcaacagatg aagattgcta tggtagagca tagaaaaaaa
     1441 tacttagatg caaccgatgt tcattataca aaatacaaaa atatttgaag ttcatagagt
     1501 aaaagaagag tcagtatacg ccctccaatc agatttggca cttagtatgt cgccgttgta
     1561 tagctaactt accacaacaa atacctgtaa agtggattca agacagagtg ttatttagag
     1621 atagaattcc tacatataaa ggttatagaa gacaatttaa tcaaatatta ttaggtgcat
     1681 ggggaataga atcagcttat gtggatgcag aaataatagt tgcaacttgg cgaggcttgc
     1741 aacgatttaa aggaatttaa agtagaattt attcaactgt ctaacaaaaa tatatttgat
     1801 gt
//
LOCUS       DAUNLR010000101         1570 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUNLR010000101 DAUNLR010000000
VERSION     DAUNLR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.101"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            80..439
                     /locus_tag="VLL59_001739"
     CDS             80..439
                     /locus_tag="VLL59_001739"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509835.1"
                     /translation="MTKDKRTGWLAELNPGDKIILVNNPRWFKTSRTVRAVSKITPTG
                     RINIDNFQFMPDGVCLNGNNYYLEEATDEVISEVLKENEYRHFRNSVIEKFESKIKED
                     DLLTTDQLKAIDTILNN"
     gene            460..651
                     /locus_tag="VLL59_001740"
     CDS             460..651
                     /locus_tag="VLL59_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509836.1"
                     /translation="MPNNASAIEKIKKYLLDNNLKQVDLAVTYDKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            725..997
                     /locus_tag="VLL59_001741"
                     /pseudo
     CDS             725..997
                     /locus_tag="VLL59_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
     gene            complement(1138..1320)
                     /locus_tag="VLL59_001742"
     CDS             complement(1138..1320)
                     /locus_tag="VLL59_001742"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509837.1"
                     /translation="MAKDLLEVTSEIIIGNHESFYREFRAAKNEGKIKDATFAEYLGL
                     EYKKLYQYVSNVNSID"
BASE COUNT          612 a          265 c          264 g          429 t
ORIGIN      
        1 aaaaatttaa atttttacta actttattac ttacaaaata aaaacttcca agtgggagcg
       61 gaaaggatgg aaataacaaa tgacaaaaga caagagaaca ggatggttag ctgagttaaa
      121 tccaggagat aaaattatct tagtaaataa tccgcgatgg tttaaaacat caagaacagt
      181 tagagctgtt tctaaaatca caccaacagg tcgaatcaat attgataact ttcaatttat
      241 gccagatggc gtttgtttaa acggcaacaa ttattatcta gaagaggcaa ctgatgaagt
      301 tatatcagag gttttgaaag aaaatgaata tagacatttt cgcaattcag tgattgaaaa
      361 atttgaatca aaaattaaag aagacgattt actgacaaca gatcaactaa aagcaattga
      421 tactatttta aataactaat tttagaaagg aggcactcaa tgccaaacaa cgcatcagca
      481 atcgaaaaaa ttaaaaagta tttgcttgat aacaacctta aacaagttga tctagcagtt
      541 acttatgaca aagaaccgca agatgtagcg aatattctcg ccggacgaaa aaaagaccca
      601 gcatcaaatc gctttgtttt aaaagttatt tcagatttaa aaatcagata gaaaggcatc
      661 aaatgaatca aataatcaat attacagtaa acgataacca tgaaccagtt gtcagtggtc
      721 gggacttgca aagttactca agcagaatgg ggtaaatatt ggagcgactc gtctcttcac
      781 ttggcttcgt aaacacggct atcttatcaa gcgtaatggc cgagattgga atatgcctac
      841 tcagaaaagc gtagagcttg gacttataag ggtcaaggaa actagcatca cccattctga
      901 tggccatatt acagtaagca agacacccct tgtaaccgga aaaggtcaac aatactttat
      961 taataaattc cttaatcagg aatatctacc agtttaaaaa ggagatagca tgaacgaaat
     1021 aacatttacc ctatattgca caacatctga agaagcaatc acggaagtaa agaaactaaa
     1081 agaagcccat ccaaaggata gacttcaatt caatgtaaac attaagtctg agttttacta
     1141 gtcaatagaa ttgacgttag aaacgtattg ataaagtttc ttatactcaa gacctaagta
     1201 ttccgcaaaa gtagcatcct taattttacc ttcgtttttt gcagctctaa attcacgata
     1261 aaaactttcg tgatttccga tgataatttc tgatgttact tccaacaaat ctttagccat
     1321 ataatcacct cccttcgaga tgattataac aaaaaaagtc cgacggcaat cggactctga
     1381 acaaaaatat tacaaaggaa ttataccatg aaacgacaaa aagaacaatg gaccccaaag
     1441 gttcgctgtt ttaggaaaga tggttcacaa tgtgagccag aaaatataac ggtgccaatt
     1501 tcttttacag gttactatca aattttatta gaactaggag tataacatga aactattaga
     1561 ttttattttt
//
LOCUS       DAUNLR010000102         1552 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUNLR010000102 DAUNLR010000000
VERSION     DAUNLR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1552
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.102"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(256..1377)
                     /gene="mnmA"
                     /locus_tag="VLL59_001743"
     CDS             complement(256..1377)
                     /gene="mnmA"
                     /locus_tag="VLL59_001743"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HER6509838.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          493 a          328 c          251 g          480 t
ORIGIN      
        1 cgaaatacct aatcatcaaa atatctgttg taatactaga gaaagtgagt ctcatgatcg
       61 tatgatttct acagtaacta ataaagtaat gactcaactt ttacgaacta tttttaaaaa
      121 taatgtgatt atatttaaaa tatacagata tcataaatta atccattaac gcatgattgg
      181 tttttataaa taatatcata tgatgtcaaa ggaattgttg aatgtccctt tctttttatc
      241 ttaataaaag attcattaaa tgtactgaca aggctgccca tttttataag ccatgtcaat
      301 cataccacca ccaaggcatt cttttccgtc atagaaaaca acagcttgac caggagtaat
      361 cgcgcgctgt ggctctgcaa aaacaacttc tgccttatct cctcgaacat gcaccgccac
      421 gtgtgaatcg ggttgacgat agcgaaattt agcagtacat tcaaatgtga actcttctgg
      481 catctcacgt gtaaaatgga tgactgaggc gtcaagacta tttgacatta gggcttcatg
      541 gtagaaacct tgaccaacgt ataaaatatt ttgcgacaaa tctttaccga caacaaacca
      601 aggttgatta tccccaccat gctgaccacc aatgcccaga ccaccacgct gaccaatagt
      661 ataatacata agaccagcat gttctcccat atcgcgacca tcaatagtca tcatgcgacc
      721 tttttgtgcc ggtaagtact ggctcaaaaa ctgtttgaaa ttcttttcac caataaaaca
      781 aatacctgtt gaatctttct ttttagccgt tgcaagccct gctcgctcag cgatttctct
      841 aacttctgac ttttgcaaat gaccaagggg gaataaagtc ttttgtagtt gttcctgtga
      901 tagttgactt aaaaagtagg tttggtcttt gccattatca gctccacgta acatgtgaac
      961 cgtaccattt tcatcacgct tgacttgagc atagtgtccc gttgctacat aatctgcacc
     1021 taaagtcatg gcatagtcaa ggaaagcttt aaattttatt tccttattac acatgacatc
     1081 gggatttgga gtacgacctg ctcggtattc ggccaagaaa tattcaaata ctctgtccca
     1141 atattctttt tcaaaattga ctgaatagta aggaataccg atttgatcag caacggctgc
     1201 tacatctttg taatcttcag tagctgtgca aacaccaaat tcatctgtat cgtcccagtt
     1261 tttcatgaag acaccaataa catcataacc ttgctccttt aaaagtagag ctgttacaga
     1321 tgaatcaacg ccaccactca taccaacgac aacacgtatc tttgagttat ctgtcataaa
     1381 aaattctccc atcaataata agatagaaaa agataatcat catattatga atattatgat
     1441 tctttttctt atcagttaac gtacgattga aggtcgtcgt tttcaaaagt cgatttgaag
     1501 gtcgattttg aagcgccatc agcgcaaacc ttattataac aattactgcg tg
//
LOCUS       DAUNLR010000103         1530 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUNLR010000103 DAUNLR010000000
VERSION     DAUNLR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1530
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.103"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..551
                     /locus_tag="VLL59_001744"
     CDS             <1..551
                     /locus_tag="VLL59_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509839.1"
                     /translation="YSNYRRNNLQVELIAAPVSDWILSVILDNGESIYNPNGTLRANI
                     KIINPSNVDVSYFDLIVFDKNRKYQHYYQKQNNIINDLTGREAIAAVQPDGNTILIEV
                     PEADCGVLKAHSMTRMDLIIQTSEITDRLFVAFKVAKKKKLFKANKAGYVNSPYQSFS
                     ASFPVELSKKPHYEDILKDLHE"
     gene            complement(650..808)
                     /locus_tag="VLL59_001745"
     CDS             complement(650..808)
                     /locus_tag="VLL59_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509840.1"
                     /translation="MSWKKLMLGDLEHTFTSRDGKEKTSVEFEGGVLPALLVLGGITW
                     LIAWFITK"
     gene            867..1082
                     /locus_tag="VLL59_001746"
     CDS             867..1082
                     /locus_tag="VLL59_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509841.1"
                     /translation="MKISNSKDLALAIVASSSPTLSIEDKIKLYEDSVEAIKQHNLPF
                     VEAEKQEQINNGKVIVEALERGESLFG"
     gene            complement(1068..1217)
                     /locus_tag="VLL59_001747"
     CDS             complement(1068..1217)
                     /locus_tag="VLL59_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509842.1"
                     /translation="MRERNEKFIGVLKDMHMQILRDFTNEEDPLTRCELAKGFLEIGD
                     YLSKQ"
BASE COUNT          483 a          295 c          252 g          500 t
ORIGIN      
        1 cttattcaaa ctaccgaaga aataacttac aagtcgagtt aattgctgct cctgtttcag
       61 attggatttt gagcgttatt ttagacaacg gtgaaagcat atataatcca aatggtacat
      121 taagagctaa cattaaaatc atcaatcctt ctaatgttga tgtaagctac ttcgacttga
      181 ttgtttttga taaaaacaga aaatatcagc attattacca aaagcaaaat aatataatta
      241 acgatttaac aggtagagag gctatagccg cagtacagcc tgatggcaat acaatcctta
      301 tcgaggttcc agaggcagat tgtggagtat taaaagccca cagtatgaca aggatggatt
      361 taatcataca aacgtctgaa atcacagata gactctttgt tgcttttaaa gtagctaaaa
      421 agaaaaaact atttaaagct aataaagcag gatatgttaa ttcaccttat caatcatttt
      481 ctgcgtcatt ccctgtggaa ttatcaaaaa aaccgcacta cgaggatatc ctaaaagatt
      541 tgcatgagtg agagcagatt ttcttgtgtg aaatatcttg gaagaaccta gtacaccgta
      601 tttaattttt tccatgcctt ccctcctttc cactcctttt ggggagtttt tattttgtaa
      661 taaaccaagc aatcagccaa gtgataccac ctagcactaa cagagctggt aatacaccgc
      721 cttcaaattc aacgcttgtt ttttccttgc catcacgact agtaaacgtg tgttctaagt
      781 cgccaagcat tagttttttc caactcattt tgtacctcct aaaaatgtta taatcaactt
      841 atcctagcag aaaggaggat aagctaatga aaatttctaa ttcaaaagat ttagctctcg
      901 ctattgtcgc ttcttctagc cctactttgt ctatcgaaga taaaatcaaa ctttacgaag
      961 actctgtgga agctattaag caacataatt tacctttcgt tgaagccgaa aagcaagaac
     1021 aaatcaataa tggtaaagtt atagtcgaag ctcttgagcg tggcgagtca ttgtttggat
     1081 aaatagtcac caatttcgag gaacccttta gcaagctcgc accttgttaa ggggtcttct
     1141 tcgtttgtga agtctcgcaa aatttgcatg tgcatatctt ttagcactcc gatgaacttt
     1201 tcatttcgtt ctctcataac ctctcctttc attcttgcgg agatacagcc aatgtgctaa
     1261 actaaactta ccccgttagg ggagagggct tcttagccct ctaattatcc tcaccactct
     1321 attgagtagt gaatcttaag cttaaaccaa agaatcttga tttcgacttc tagttctttg
     1381 cgtttaggct ttttgtttag cctagatttc attagctgta cctcctttcg ttttgcttaa
     1441 ttccttaagc ttgattatat tgatccgttt taaaacgaat gtaaagtata aaaacgaaaa
     1501 aaaacgaatt ttttttaaaa ttttatttac
//
LOCUS       DAUNLR010000104         1381 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUNLR010000104 DAUNLR010000000
VERSION     DAUNLR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.104"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(54..185)
                     /locus_tag="VLL59_001748"
     CDS             complement(54..185)
                     /locus_tag="VLL59_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HER6509843.1"
                     /translation="MTIKNQKKYKGVYCDKNGKIFYQADLGVDPVTGKRVQKKARKN"
     gene            complement(188..408)
                     /locus_tag="VLL59_001749"
                     /pseudo
     CDS             complement(188..408)
                     /locus_tag="VLL59_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            495..638
                     /locus_tag="VLL59_001750"
     CDS             495..638
                     /locus_tag="VLL59_001750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HER6509844.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            complement(709..927)
                     /locus_tag="VLL59_001751"
     CDS             complement(709..927)
                     /locus_tag="VLL59_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HER6509845.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNK"
BASE COUNT          446 a          275 c          185 g          475 t
ORIGIN      
        1 atccgaacca gttcatcata cgcttctttc attgtaccaa atggctttcc atactaattc
       61 tttctggctt tcttttgaac tcgtttacct gttactggat ctacaccaag atcagcttga
      121 taaaatatct tcccattctt atcacaataa acacctttgt actttttttg attttttata
      181 gtcatcttta attctcactt tctaaacttt cttcagagag tagaacacct actaactctt
      241 ctacaatatc tttaggagca ataccaagtc ttctattgtc aaagggcgat ttacttaatt
      301 gtaccgcatt ttgttcaagt tcgcgagctt cttcaacttt tttatagcta ttctttttgc
      361 ttctctaata atatttcttg cagtatgttc gagaaaacca atattcatca agctttttat
      421 atgttactat tttcacacct ccactccttt caaaaaaatt acaacctccg tgggtatgac
      481 tggttaaatc actcatggga atctcaccca ctggcctttt acgctggcag cctgaacgtt
      541 cagaagtatc attgtcccta tttgtggtca tggcagatag agaaccactc tattttatag
      601 ctaataatta tcgctcctat cacggcgtat ctcactaaat tgctcgacaa acaagaaagt
      661 cccacctcgg tttattcagt tgtcaatgaa caaatcaagg cgagactttt atttattatg
      721 aaaacgatac ggataatctg tttgccctaa taaataatca atactgacgt tatagagttt
      781 agaaaactgc acaagaacat ctgccattaa ggcaacctct cctctctcaa tttttgcata
      841 atttgcatga gagaaggaaa gtaaatttgc aacaaacttt tgagtgaaat cgttatcttc
      901 tctcaaattc ctaatacgcg gatacatcta acattctcct aatatcagta taaaggagat
      961 ttgattaaaa aatgtttaat tgtcctattt ggacaagact attaaatata agctagtaat
     1021 ccattgaaat tttatagtca ttttttagtt aaacaagtta gatagtattt ataacttaaa
     1081 aaatcatatt tattgctagg taaacaaaat agatgtattt aactacttgt caaacagtct
     1141 tgattccaac ttttaaatat tcgtatatga agtaaagcta ctgtgcatga aacaaaaaat
     1201 ataacaataa gtggaacaat tgccattttc tgttggttat atagagtatc tgatattctt
     1261 aaaagccatg cccatggaat aagaaaccat accttatcac caaggctcgt ttcacaaaat
     1321 gctgcagcaa taacacctac cattgaaata cctaatgcca cacctgtact aaatatatag
     1381 c
//
LOCUS       DAUNLR010000105         1381 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.105, whole genome shotgun sequence.
ACCESSION   DAUNLR010000105 DAUNLR010000000
VERSION     DAUNLR010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.105"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..471
                     /locus_tag="VLL59_001752"
     CDS             <1..471
                     /locus_tag="VLL59_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HER6509846.1"
                     /translation="FCKESILFLNNTIEFSDDERLVCATYLVLYYLNHFFKDKETRRS
                     FLFENYTGKYKKDFKNLPIDLPIEYMKSLNGVTSALDRYDFFQEMDRYLMSYMKEYNR
                     FGGTNDIYNTKFNLVGSFLHLSMNRLNGIDREFEEKVYCFAYYTLNAQQYIEWE"
     gene            477..1166
                     /locus_tag="VLL59_001753"
     CDS             477..1166
                     /locus_tag="VLL59_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HER6509847.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESTILPLLNKVGLGDIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLANFIGFIYEGKIVLEKEYDGSENLEEL
                     FNNQILFEKRR"
     gene            1172..>1381
                     /locus_tag="VLL59_001754"
     CDS             1172..>1381
                     /locus_tag="VLL59_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HER6509848.1"
                     /translation="MVQIFLSNLLKIKNTSISKLILIFPIICVMLSLLFSALGGESIL
                     RLTAETTVNQWGVIWINVIIAVNSGL"
BASE COUNT          493 a          162 c          254 g          472 t
ORIGIN      
        1 ttttgtaaag aatctatctt atttcttaat aatacaatag aattttcaga tgatgaaaga
       61 ttagtttgtg ctacttactt ggttctatat tatctaaatc actttttcaa agataaagaa
      121 acaaggcgct ctttcttatt tgagaattat actggaaagt ataagaaaga tttcaaaaat
      181 ttgccaattg atttacctat tgagtatatg aagagtttga atggagtcac ctcagctctt
      241 gatagatatg attttttcca agaaatggat agatatctca tgtcttatat gaaagagtat
      301 aatcgatttg gtggtacaaa tgatatctat aatactaaat tcaatttagt aggaagtttt
      361 ttacatctat caatgaatcg attaaacggg attgatagag agtttgaaga gaaagtgtat
      421 tgttttgctt actatacact aaacgctcag caatatatag aatgggagta actaatatgt
      481 tgaaaataca aaatctaaaa aaatcttatg gtaagagaac catattgaat aatgtcaata
      541 tgaatattcc taagggaaaa gtgtatgctt taatcggtcc aaatggtgct ggaaaatcaa
      601 ctattatgaa aattttgaca ggcttagtta gtaagacaag tggttctatt atttttgaag
      661 gtagagaatg gtcacgtcgg gatctgcgaa aaatcgggag tattattgaa gaaccaccac
      721 tttataaaaa tttgagtgct tacgataata tgaaggtagt tacaacaatg cttggtgttt
      781 cagaaagcac tatacttcca ttattaaata aagttggtct aggagatatt gacaagagac
      841 cagtaaaaca attttctctt ggaatgaagc aacggttagg tatagctatc tctttaataa
      901 attcacctaa actacttata ttagacgaac ctactaatgg cttggaccca attggaattc
      961 aagaattaag ggaaattata gagtcattta aatcagaagg aatgacaatt atgatttcaa
     1021 gccatatact gtcagaagtt gaacatctag ctaattttat tggatttatc tatgaaggaa
     1081 agattgttct ggaaaaagaa tatgacggct ctgagaatct tgaagagtta ttcaataatc
     1141 aaattttatt tgaaaagagg agataggggc tatggtacaa atttttttat caaatttatt
     1201 aaaaataaaa aatacgagta ttagcaagtt gattcttatt ttccctatta tttgtgtgat
     1261 gttatcttta ttgttttcag cattaggtgg tgaaagtatc ctacgtttaa ctgcggaaac
     1321 aacagtaaat cagtggggag ttatttggat taatgttatt attgctgtaa attctggttt
     1381 g
//
LOCUS       DAUNLR010000106         1365 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.106, whole genome shotgun sequence.
ACCESSION   DAUNLR010000106 DAUNLR010000000
VERSION     DAUNLR010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1365
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.106"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            119..1363
                     /locus_tag="VLL59_001755"
     CDS             119..1363
                     /locus_tag="VLL59_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HER6509849.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNKNIIERIYTSSYIDSSYSIKNWIKGVNEVN
                     KADIIKVANLLKLQTVYFLEGI"
BASE COUNT          500 a          204 c          210 g          451 t
ORIGIN      
        1 aaactatatt ttactaacac tagaatcccg acaattaagt caaaaaaagt tatcactcac
       61 ctaacctgaa taaaaatggt ataatcgtaa ggatcacact atttattaag gaaacattat
      121 gaaaattgtt cagggagtac aacttcatct gattaagacc aaacagttta aaaccaatca
      181 tattaccttt cgtttttcag gtgatttgaa ccaaaaaaca gtagcaaaaa gagtcttagt
      241 ggcacagatg ttagcaacag ctaatgagtg ttatccaact gttaggcagt ttagagaaaa
      301 attagcacga ctttatggag ctagcttgtc aactaacgtg ttaacaaaag ggttagttca
      361 tattgtggat atcgatatta cttttattca agatagatat gcttgcaatg gggaaaaaat
      421 actagatgaa atgattcagt ttttaaaaga tatcttgttc tcacccctat tatccatcgc
      481 ccagtatcag cctaaagttt ttgagactga aaaaaataat ttgattaact acatcgagtc
      541 agatagagag gattcttttt actacagctc tcttaaggta aaagaattgt tttattgtaa
      601 taagaatcta caaatgtcag aatatggtag cccagaacta attgcaaaag agactgccta
      661 tactagctat caagaatttc ataaaatgct caatgaagat cagattgata ttttcatttt
      721 aggagatttt gatgattatc gcgttgttca gctaattcat caatttccac ttgataaccg
      781 aaataaaaac ctaaatttct ttcatttaca aaattctgtc aatattatta aagaatctat
      841 tgaaaaaaga gcagttcatc aatctatttt acaattagct tatcacttcc cttcagtttt
      901 tggacaacgt gactattatg ctttagttct tttaaatggg ttgttaggct cttttgcaca
      961 ttcccgtctc tttataaaaa ttagagaaga agaaggactt gcttatagta tagggtgtcg
     1021 ttttgatagt tatacaggtt tatttgaaat ttatactgga attgacagtc aacatcgcac
     1081 taaaacgtta caactaatca tccaagaatt aaatgccatt aaaatgggac gattctcaga
     1141 acaattgatt aaaaagacca gatcgatgtt gttgaataac gccttattat cagaagatta
     1201 taataaaaat ataattgaaa gaatatacac atcttcttac attgattctt cttattctat
     1261 taaaaattgg attaaagggg ttaatgaagt taataaagca gatatcatta aagtagctaa
     1321 tcttttaaag cttcaaactg tctatttttt agaaggaata taaaa
//
LOCUS       DAUNLR010000107         1202 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.107, whole genome shotgun sequence.
ACCESSION   DAUNLR010000107 DAUNLR010000000
VERSION     DAUNLR010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1202
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.107"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            154..435
                     /locus_tag="VLL59_001756"
     CDS             154..435
                     /locus_tag="VLL59_001756"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HER6509850.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(917..1004)
                     /locus_tag="VLL59_001757"
     tRNA            complement(917..1004)
                     /locus_tag="VLL59_001757"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(968..970),aa:Ser,seq:gct)
     gene            complement(1014..1087)
                     /locus_tag="VLL59_001758"
     tRNA            complement(1014..1087)
                     /locus_tag="VLL59_001758"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1051..1053),aa:Ile,seq:gat)
     gene            complement(1122..1192)
                     /locus_tag="VLL59_001759"
     tRNA            complement(1122..1192)
                     /locus_tag="VLL59_001759"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1158..1160),aa:Gly,seq:tcc)
BASE COUNT          403 a          266 c          162 g          371 t
ORIGIN      
        1 atcttcactc agacacctta tccttcttag aatgaatttt tagttactta tccacaggtt
       61 aataacttct tttcgcctaa aatattatcc acaatagtga cattttctat tatcagttat
      121 agtataattt cattaggaat ctaaaacctt agcatcacgg ttttaaatta tgtaaatgct
      181 ggggacgcaa aaagcattca taatcatctc tttcattata ccagacaggt gagaaggcat
      241 gtcaaagtta ttaccatagg catactcagt gcccactact atgagattac tatgcttttt
      301 ctacaggcta aaattatcct cgattgtttt catatccccc aacgtcttag acaagctata
      361 actcgctttc gtatccgaat cataaatact tctgctataa aacctatcgc gtatagaact
      421 ctcaaacttt actgaaaact catacagcat gattcacgga agctcatcaa taatagcttt
      481 attgcccaat ttttcgtacg cccataacta acatctagaa aagaaaagct cttactcaca
      541 agatctctga atttcaataa ttattcctaa ctctatcaac tcttgctctt cccatttttc
      601 agacaatttt taaaattttt ctaaaagaaa agaaaagaaa acaagattag caatatactt
      661 aaactcaact actctaaggc caaattagaa acagtcaaca accttatcaa agccatcaag
      721 ttaaacgttt tactcctcta cagtagtcaa agagcctatc attttggtta tcgaaataat
      781 gaacgattta aatattctat ttagttggtt ttgaagatta caaaaaaaag acgataaccg
      841 tcttctttcc cccttattta taattcatcc tttaatatgt ttcatttaac atattaacca
      901 aaatatcttt acaaaacgga gaataaggga ttcgaaccct tgcgccagtt acccgaccta
      961 acgatttagc aaaccgtcct cttcagcctc ttgagtaatt ctccaaatat atatgggcac
     1021 gagtggactc gaaccaccga cctcacgctt atcaggcgtg cgctctaacc acctgagcta
     1081 cgcgcccaag cttttattga tatagcttgg gaaaactata aagcgggtga cgagaatcga
     1141 actcgcgaca acagcttgga aggctgtagt tttaccacta aactacaccc gcaatatgat
     1201 aa
//
LOCUS       DAUNLR010000108         1043 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.108, whole genome shotgun sequence.
ACCESSION   DAUNLR010000108 DAUNLR010000000
VERSION     DAUNLR010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.108"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..>1043
                     /locus_tag="VLL59_001760"
     CDS             <1..>1043
                     /locus_tag="VLL59_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HER6509851.1"
                     /translation="IGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAINKLLCKAK
                     NINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNILKINKKATIVIKSTV
                     PIGFTEYLRNQFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNESRNSQLFLDILTDI
                     SVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIEAMGYD
                     QRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKTILN
                     SSAKTIGIYRINSKKDSDNCRESSTIDVAKLLKSSGKDVIIFEPLINQKKFLGCPLIN
                     DFNEFIKYSDIIV"
BASE COUNT          382 a          154 c          166 g          341 t
ORIGIN      
        1 gatagggctc ctacttgcaa aggaacacga cgtcaccttt tttgatattg ataataaaaa
       61 aattgattta ataaataaaa ggcaatcccc ccttaaagaa gcagctataa acaaactttt
      121 atgtaaggca aaaaatatta atgcaacttc ttctgaagaa ttagcatata aggatgcgac
      181 tttcataatc ttgtctttgc caaccaacct aaaatttaat aagcttgata cttccattat
      241 cgaaatttct gtaagtaata ttttaaagat aaacaaaaag gctacaattg taataaagtc
      301 gacagttcca attggtttta cagaatattt aaggaatcaa tttcactaca acgatatcat
      361 tttttcacct gagttcctta gggaaggatc aactattcat gatcaattgt atccttcgag
      421 aactatagtt ggaaatgaat ctagaaattc tcaattattc ttagacatac taacagatat
      481 atcggttgaa aaagactcgc catctttatt agttggctct tctgaagcag aagcgataaa
      541 gttattttcg aatgcatact tggcacaaaa aattgctttt tttaatgagt tggatacgtt
      601 tgctgaaatg caaaatttgg actcaaaaaa aattattgag gctatgggat atgaccagag
      661 aataggaaat tcgcacaata atccttcttt cggttttggt gggtactgtc ttcctaagga
      721 tattaagcaa ttagagtatc attttaaaga aattccagca ccaattatta ccagtataag
      781 tgagtctaat ttattaagaa aaattcatat agcaaaaacg attttgaaca gctcagctaa
      841 aacaatagga atttatagaa ttaattccaa aaaagattcg gataattgta gggaatcttc
      901 tacaattgat gttgctaaac ttctaaaaag cagtggtaag gatgttatca tctttgagcc
      961 cttaattaac caaaaaaagt ttttggggtg ccctttaatt aatgatttta atgaatttat
     1021 taaatattcg gatattatag ttg
//
LOCUS       DAUNLR010000109         1009 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.109, whole genome shotgun sequence.
ACCESSION   DAUNLR010000109 DAUNLR010000000
VERSION     DAUNLR010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1009
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.109"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            162..>1009
                     /locus_tag="VLL59_001761"
     CDS             162..>1009
                     /locus_tag="VLL59_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HER6509852.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYA"
BASE COUNT          342 a          142 c          189 g          336 t
ORIGIN      
        1 aggtcgtttt tttaaaaaaa tagtttagag aatttgagtt aaaatgacaa gggaatcttg
       61 attgaagttg attttttgaa agataattgt ataatggaaa cgaaatacat gacaaaccca
      121 tgataaggtt tatctttggt aaatatagta acgaggttaa tatggtaaca ataaaagatg
      181 tcgctcaaaa ggcaggtgtt aacccttcga cggtgagtag ggtattaaaa gataatcgat
      241 ctatttctat gaaaacaaaa gagaaggtta gaaaagcgat ggcagatttg ggatatgttc
      301 caaatgtcgc agcacagatt ctagcgagtg gtttgacaca caatatagga cttgtttttc
      361 ctcctattac aactagcgat agattaagtg aacctttctt tatggaaatt ttgtcgacta
      421 ttactaacga agctaaagaa tctcatttta ctgtgtcgat tgctacaggt atatctcttg
      481 atgacctgat agagcaagtg aaactgatgc atcttcaaaa acgagttgat ggttttatta
      541 ttctttattc tgatcaagat gatcctgtca aaaaatattt gatgacaaat aacttaccat
      601 ttgtcattgt aggtgctcca caaggtgaca ctaataaaac cacttatatt gataatgata
      661 atcagctaat ggctaaaaca gcagtagaac acctttatca aaaaggccat cacaacatat
      721 tatttataac agatgattta ctatcagaag taacttctga gcgttatctt ggctatttga
      781 agggttgttt taagcgatct ttaaaaacaa agccaatgct gttatttgat cgtaaggatc
      841 ctgttagcgt agaaatattg atggaaacta tatcttcctt taaagcaact gccttggttg
      901 ttgttggtga tgttctggct attcgtatgg tacagttatt atctttttat gatataaaag
      961 tgccagatga tatgtcaatt atcactttta ataattctaa ttatgctaa
//
LOCUS       DAUNLR010000110          966 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.110, whole genome shotgun sequence.
ACCESSION   DAUNLR010000110 DAUNLR010000000
VERSION     DAUNLR010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..966
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.110"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..923)
                     /locus_tag="VLL59_001762"
     CDS             complement(<1..923)
                     /locus_tag="VLL59_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HER6509853.1"
                     /translation="MTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYF
                     DTENNIIKALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLG
                     SIETTSLMNFYGQEEKYHTITVRVHIKNYPAVAYMMAVVNVEQLDRANERYERIIIIV
                     MSVFWLVSILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNRLESLFRK
                     PNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENY
                     ELVAKEYGKIFYFQNQVNRSLRMDKALLKQL"
BASE COUNT          339 a          178 c          139 g          310 t
ORIGIN      
        1 attaattgtt ttagtaaagc cttatccatt cttaacgatc tattgacttg gttctgaaaa
       61 taaaatattt ttccatattc tttagcaact agttcataat tctcaaaaat agcattaaaa
      121 aaatctgtat ctaaatgagt ccactgtgga ttaatgccat catctcgtct tgctaaattt
      181 aataaattag ttgttaagat gcgcatgttg cgaacctcgt ctaaactaga agcgagatgc
      241 tcactatttt ctaatatcgt ttcgttgggc ttacgaaaaa gcgattccag acgattctgt
      301 aagaccgcca aaggggtcct tagttcatga ctagcatttt caacaaacat tttttgtttt
      361 tcatagcttt ctaaaatagg ttttctgctc cacttggcta aataaatact tgctaaaata
      421 gaaactagcc aaaaaacact cataactata ataataatgc gctcgtaacg ttcattagcg
      481 cggtctaatt gttccacatt tactactgcc atcatatagg caactgcagg ataatttttg
      541 atatgaaccc ttacagttat cgtatggtat ttttcttctt gtccataaaa attcattaaa
      601 ctggtggttt caatactccc caaccggcgt ttatctaaat gaaaattttg atagttagaa
      661 aacgcatcaa aagcatttaa aattgttcca ttagcactaa acaaaatgat atctgtatta
      721 gctgcaggcg ttcctaataa cttagaacta tctgaatcag gcagcgcctt aataatgtta
      781 ttttcagtat caaagtaaaa agaagatatt ctagccatcg tacgattagc atagctactt
      841 gcattattac taacagaaac taaactactg tcaactgacg aataaacgcc aaaccgcata
      901 atctgtaaga taataatagt cataatgaca aaaatacctg taaaaaccgc aaaaaaatga
      961 aaaaag
//
LOCUS       DAUNLR010000111          932 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.111, whole genome shotgun sequence.
ACCESSION   DAUNLR010000111 DAUNLR010000000
VERSION     DAUNLR010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.111"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..288
                     /locus_tag="VLL59_001763"
     CDS             <1..288
                     /locus_tag="VLL59_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HER6509854.1"
                     /translation="DKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNGKYF
                     STMPLINYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            343..>932
                     /locus_tag="VLL59_001764"
     CDS             343..>932
                     /locus_tag="VLL59_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HER6509855.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSY"
BASE COUNT          352 a          102 c          178 g          300 t
ORIGIN      
        1 gacaagaaag aaaagcaaat ttatcattca atttggagtg atagtttagc aagtttatat
       61 ctaaatgagc tattgggaag gcatatttct ggacaggttg catgttttca atcagataat
      121 ggaaaatatt tttctacaat gcctttgata aattatgaaa aaaataatcg ggtacgagaa
      181 cagatagtga agggtatttt tgctaaacaa aaattattta aaattacagc agctacgcca
      241 gctaagattg cagaagcgat tatagaaaat gttaagaaaa actcatagtg tgggtgaatt
      301 tggggattaa tatgaagtat tgaaaaagga gtaagagtaa ttatgtttgt gataggcatt
      361 ccaactttaa atgaggcaga taatatcagt agattagtta aacaaattga tgagtatgct
      421 gtaaatttag ggaaagaaat tattattatt aattcggata gtaaaagtac agatggaact
      481 ccgcagattt ttttagaaac caaaacttat aacaccaaag tttcgatagt atcagaagct
      541 aaaggaaaag gttataatgt gagaaatatt ttcgaatatg caataaatca tgtgccgaat
      601 ttctccggtt taattttgat tgatggagac gttgtctcaa tgaaaaaaat gtggttagaa
      661 aagatgttta tagcaattga atctggaaat gatcttataa tcccaaatta tgctagaaaa
      721 tcttttgaag gaaatgcgac aaaccatttt atttatccca tgttagtgaa atttttcaaa
      781 cgtgatatgc cttatcaatg catctctggt gattttggat tttcaagagg attgataaaa
      841 gatttaactt tgaagtgtaa ttggcacaaa tatacattag gttacgggat agatattttt
      901 ttaaccttaa cagctatatt aaagtcatac aa
//
LOCUS       DAUNLR010000112          882 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.112, whole genome shotgun sequence.
ACCESSION   DAUNLR010000112 DAUNLR010000000
VERSION     DAUNLR010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.112"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            58..330
                     /gene="rpsP"
                     /locus_tag="VLL59_001765"
     CDS             58..330
                     /gene="rpsP"
                     /locus_tag="VLL59_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HER6509856.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            340..579
                     /locus_tag="VLL59_001766"
     CDS             340..579
                     /locus_tag="VLL59_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HER6509857.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
BASE COUNT          287 a          148 c          156 g          291 t
ORIGIN      
        1 gaatttagcg tagctgtatt tcttatacat tactaaaaga aaagagacta tttaaaaatg
       61 gcagtaaaaa tccgtttaac tcgtatgggt tctaagaaaa aacctttcta ccgtattaat
      121 gttgcagatt cacgtgcacc acgtgatggt cgttttatcg aaacagttgg aacatacaac
      181 ccattagtgg ctgaaaatca aattactatt aaagaggatc gtgttcttga gtggttatct
      241 aaaggagcgc agccttctga taccgttcgt aacatcttgt ctaaagctgg tgttatggct
      301 aagttccacg accaaaaatt ctctaaataa taacagccta tggataccat tgaaaatctt
      361 attatcgcta ttgtgaaacc tttgatttca caaccagata atcttaccat taaaattgaa
      421 gatactcctg actttttaga gtatcatctt gacttggatg ctcaagacat cggtcgtgtt
      481 atcggcaaaa aaggtcgaac tattactgcg ataagatcga ttgtctactc ggttccaaca
      541 ctaggaaaaa aagttcgctt agttattgat gagaaataat cactaacttg agatggattg
      601 aaaagcttgt tgacttaaag tcaacaagct ttttgaatag caaaaatctt aatatttctg
      661 aaatgaaaag attagatttt tctgtcttta actaaaaaga agttaaagaa tggcttagct
      721 gattgccttt ataagagatt atactggttt ttgatagctg ctgtcatgta aaatagctac
      781 aattcatctt acgagattga ccttagcatt gccagtgcag tctttatttt ccaacctgct
      841 gtttgttgta tgtttatagt ttcctaaaaa atgctctctc ag
//
LOCUS       DAUNLR010000113          781 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.113, whole genome shotgun sequence.
ACCESSION   DAUNLR010000113 DAUNLR010000000
VERSION     DAUNLR010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..781
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.113"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            223..468
                     /locus_tag="VLL59_001767"
     CDS             223..468
                     /locus_tag="VLL59_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HER6509858.1"
                     /translation="MIKFAEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGA
                     GMAILGVGGVAGVFAGAHVGAIAGGLTCVGGMLFNGK"
     gene            483..665
                     /locus_tag="VLL59_001768"
     CDS             483..665
                     /locus_tag="VLL59_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HER6509859.1"
                     /translation="MDNFLGLQFEELVNISGGKGNIGSAIGRCLGGMLIAAAGGPITG
                     GVAAFVCVASGIAAYQ"
BASE COUNT          249 a           76 c          174 g          282 t
ORIGIN      
        1 tatgttttga cacacttgat agcttatttg actaatattc aaaaactcta ctcttgtgtt
       61 tacacaacat tattgacagt ctctaatatg ttaaaaagtt tatttgagat gtttatacaa
      121 ccattcacga catagaaaaa aatttttata ataatatgct atatttagtt tgtcaaagtt
      181 gcaacaagat gaatataaca ttttagaaag gtttttaaag ttatgataaa atttgcagaa
      241 gaaatacaaa aagaagagtt gttccatatt attggaggtt atagtgctac agattgtaaa
      301 aatcatttaa ttggtggtat tacttcaggt gctattgcag gtggtgttgg agcaggtatg
      361 gctattttag gtgttggagg agttgcaggt gtgtttgcag gtgcacatgt aggtgctatt
      421 gcgggtggat taacttgcgt tggtggtatg ttatttaatg gaaaataatt ttgaggtgaa
      481 aaatggataa ttttttagga ttacagtttg aagaattagt aaatatttct ggtggaaaag
      541 gaaatattgg ttctgctatc ggaaggtgct taggtgggat gcttatagct gcagcaggag
      601 gtccaataac tggaggtgtg gcagcatttg tatgtgtagc atctggaatt gcagcttatc
      661 aatgatatga ttatagttat aatactcggt ttaatttgtc taatactttc ccaaattttt
      721 ttgaaggata aagaggtaag agaaaatgca agtaaagtaa ttttaattgt gatatttgtt
      781 t
//
LOCUS       DAUNLR010000114          748 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.114, whole genome shotgun sequence.
ACCESSION   DAUNLR010000114 DAUNLR010000000
VERSION     DAUNLR010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.114"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            <1..486
                     /locus_tag="VLL59_001769"
     CDS             <1..486
                     /locus_tag="VLL59_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HER6509860.1"
                     /translation="TRMLSEDRSVKLILVEELLSELHFEVDDLLNINNIEFSICNRLI
                     ITSFYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGEQIHFEIWNNGERFSDS
                     TLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLNNPARGGASAIISIKKK
                     I"
     gene            643..>748
                     /locus_tag="VLL59_001770"
     CDS             643..>748
                     /locus_tag="VLL59_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HER6509861.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSC"
BASE COUNT          266 a           97 c          145 g          240 t
ORIGIN      
        1 acacgcatgc tttcagagga tagatcagtg aaactaattt tagttgagga gctattaagt
       61 gagttacatt ttgaagtcga tgacttattg aatatcaata atattgaatt ttctatttgt
      121 aatagactta ttatcacttc tttttatgga gatgaggaaa atctgataag agctctttct
      181 aaccttttag ttaatgcaat aagatttatg cccgtattag ataaaaaaat cgaagttata
      241 ctgtctgagt caggagagca aattcatttt gaaatatgga ataatggtga gcgtttcagt
      301 gatagtacac tgaaaaaggg agataaatta ttttacacgg aagattatag cagaggtaac
      361 aaacattatg gaatcggttt ggcatttgtt aaaggcgttg ctatcaaaca cggtgggaat
      421 cttcaattga ataatccagc tagaggaggt gctagcgcca taatctcgat aaaaaagaaa
      481 atttaataga tttgattgaa actggagtat ttcaggcaaa aaatcgtaaa tttttgtgat
      541 ttttggctaa aatacttttt ttctgaacaa attctgaact tggggtgtca taataatcat
      601 gtaaatatat cggatgcaaa aacgtaagag aggaactaga aaatgaataa cacaattaaa
      661 gactttgatc tcgatttgaa aacaaataaa aaagacactg ctacacctta tgttggtagc
      721 cgttacctat gtacccctgg ttcttgtt
//
LOCUS       DAUNLR010000115          720 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.115, whole genome shotgun sequence.
ACCESSION   DAUNLR010000115 DAUNLR010000000
VERSION     DAUNLR010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.115"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(1..74)
                     /locus_tag="VLL59_001771"
     tRNA            complement(1..74)
                     /locus_tag="VLL59_001771"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38..40),aa:Arg,seq:acg)
     gene            complement(91..175)
                     /locus_tag="VLL59_001772"
     tRNA            complement(91..175)
                     /locus_tag="VLL59_001772"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(139..141),aa:Leu,seq:taa)
     gene            complement(184..255)
                     /locus_tag="VLL59_001773"
     tRNA            complement(184..255)
                     /locus_tag="VLL59_001773"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(221..223),aa:Gly,seq:gcc)
     gene            complement(268..340)
                     /locus_tag="VLL59_001774"
     tRNA            complement(268..340)
                     /locus_tag="VLL59_001774"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(305..307),aa:Thr,seq:tgt)
     gene            complement(351..432)
                     /locus_tag="VLL59_001775"
     tRNA            complement(351..432)
                     /locus_tag="VLL59_001775"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(396..398),aa:Leu,seq:tag)
     gene            complement(438..510)
                     /locus_tag="VLL59_001776"
     tRNA            complement(438..510)
                     /locus_tag="VLL59_001776"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(475..477),aa:Lys,seq:ttt)
     gene            complement(542..614)
                     /locus_tag="VLL59_001777"
     tRNA            complement(542..614)
                     /locus_tag="VLL59_001777"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(579..581),aa:Asp,seq:gtc)
     gene            complement(632..704)
                     /locus_tag="VLL59_001778"
     tRNA            complement(632..704)
                     /locus_tag="VLL59_001778"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Val,seq:tac)
BASE COUNT          185 a          207 c          158 g          170 t
ORIGIN      
        1 tgcaccctag aggagtcgaa cctctaaccg cctgattcgt agtcaggtac tctatccagt
       61 tgagctaagg gtgctatttc aaaaaattaa tgccgaggac cggaatcgaa ccggtacgat
      121 gtaaaccatc gcaggatttt aagtcctgtg cgtctgccag ttccgccacc ccggctcctc
      181 aaaagcgaac gacgggattc gaacccgcga cccccacctt ggcaaggtga tgttctacca
      241 ctgaactacg ttcgcaacta atctcaatgc cggctacatg acttgaacac gcgaccctct
      301 gattacaaat cagatgctct accaactgag ctaagccggc taatctttta tgcgggttaa
      361 gggacttgaa cccccacgcc gttaagcgcc agatcctaaa tctggtgcgt ctgccaattc
      421 cgccaaaccc gcttttatga cccgtactgg gctcgaacca gtgacccatt gattaaaagt
      481 caattgctct accaactgag ctaacgagtc tttccttcaa aaaatatgac tactctttga
      541 acggtcccga cgggaatcga acccgcgatc ttcgccgtga cagggcgacg tgataaccgc
      601 tacactacgg gacctgtatt ttccaatact atgggagtta acgggatcga accgctgacc
      661 ctctgcttgt aaggcagatg ctctcccagc tgagctaaac tcccattgag tgtgtcatta
//
LOCUS       DAUNLR010000116          551 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.116, whole genome shotgun sequence.
ACCESSION   DAUNLR010000116 DAUNLR010000000
VERSION     DAUNLR010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.116"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..464)
                     /gene="rgg4"
                     /locus_tag="VLL59_001779"
     CDS             complement(<1..464)
                     /gene="rgg4"
                     /locus_tag="VLL59_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HER6509862.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVR"
BASE COUNT          173 a          112 c           65 g          201 t
ORIGIN      
        1 cgtaccttag tctttatttg attaaaatat tcttgaagta agtcaatgcc aaagttagta
       61 ttctcactca ataaagtatc taaagttgcc tgtaaacaat caatgattat tttctcttcc
      121 tctggtaatt tatcataata atcctcaaaa atttcatcaa actgctcttc tcgtacttgt
      181 aattttccat catccatgta agttggtgtc cttaagataa ggtattttaa ttctttgtaa
      241 cgcttaggta gttctaaatc agcaccatca gttaagtaac cgacactaac gtttaaggct
      301 tttgcaataa aaataacctt acttaaactt ggtatggatt gacctagttc tatccgtgct
      361 aattgacgaa cagaaagttc agactcatcc ccacacaagt cctcgcgact aatcctcttt
      421 tcaagtctta acacttttac ttttccacca aaatgttcta acatggtttc tctccaacaa
      481 ctgttttctt tattatatca cagcgtctaa ttaaaaacta acctttttaa tatttttaaa
      541 gaaaatattc g
//
LOCUS       DAUNLR010000117          516 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.117, whole genome shotgun sequence.
ACCESSION   DAUNLR010000117 DAUNLR010000000
VERSION     DAUNLR010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.117"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..>516)
                     /locus_tag="VLL59_001780"
     CDS             complement(<1..>516)
                     /locus_tag="VLL59_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HER6509863.1"
                     /translation="AIELMTTLGEIALGSQTIFNILFMPAFVMNLLILFFRPYITQMA
                     IALIRGQIKEFNKIQVQLFAYLGVFSLIALVGSGLFGIPFLSMLYGTNLTDYWVDFML
                     IMLGGSIGSFATVIDNILTAMRTQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSF
                     LITMLVWLGLS"
BASE COUNT          212 a           95 c           70 g          139 t
ORIGIN      
        1 atggataatc ccaaccaaac caacattgtt attaaaaagc tcaaagcagc tcctaaaatg
       61 tgatatttca taacaaaaag attggtaatt aataacgaaa tcaaaaatcc tcctgtatat
      121 ggaataagaa gaagttgctg tgttctcata gcggttaaga tattatcgat aactgtcgca
      181 aaactaccaa tcgagcctcc tagcataatc aacataaagt ctacccaata atccgtaagg
      241 ttagtaccat atagcattga taaaaaggga ataccaaaca aaccacttcc aactaacgct
      301 atcagtgaaa aaactcctaa ataagcaaac aattgaactt gtatcttatt aaactctttt
      361 atttgacctc tgattaaagc aatagccatc tgtgtaatat aaggtctaaa aaataaaatt
      421 agcaaattca taacaaaggc tggcataaat aaaatattaa aaattgtttg agagcccaaa
      481 gcaatttcac ctaaagtcgt cattagttca atagcg
//
LOCUS       DAUNLR010000118          495 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.118, whole genome shotgun sequence.
ACCESSION   DAUNLR010000118 DAUNLR010000000
VERSION     DAUNLR010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.118"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(<1..>495)
                     /locus_tag="VLL59_001781"
     CDS             complement(<1..>495)
                     /locus_tag="VLL59_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lantibiotic dehydratase"
                     /protein_id="HER6509864.1"
                     /translation="SGQAGRSFGRFYGLSETVRETIKNLNHQNNTNVELSFVPKQIRL
                     ANVIQNYSDESYNTSFFTTSWDSENELRLEDIYIRYSDGKFHFTTIDGKNELKFTMNN
                     MLNSDSQSRVLRLLVDLSEFEYGLSHWSLFPWDILAQERVYIPEILFEDITIATAQWN
                     LSVI"
BASE COUNT          166 a          101 c           61 g          167 t
ORIGIN      
        1 ctaattactg ataaattcca ctgagcagtg gcaatcgtaa tgtcttcaaa taaaatttca
       61 ggaatatata ctctttcctg agccaaaata tcccaaggaa ataatgacca atgcgataaa
      121 ccgtactcaa actcagataa atcaaccaac aatctcaaaa ccctgctttg gctatcggaa
      181 tttagcatat tattcatggt aaatttcaac tcatttttcc catcgatagt tgtaaaatga
      241 aacttaccat cactatatct tatataaata tcctccaatc gcagttcgtt ctctgaatcc
      301 catgatgtgg taaaaaatga agtattataa gactcatcac tataattttg aattacattc
      361 gcaagtctta tctgtttagg aacaaatgac aactctacat tcgtattatt ttgatggttt
      421 aaattcttaa ttgtttctct tactgtttcg cttaatccat agaatcttcc aaagcttcta
      481 cctgcttgtc cagaa
//
LOCUS       DAUNLR010000119          444 bp    DNA     linear   BCT 04-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes isolate NS5139
            SAMN30816728-rid17249933.denovo.119, whole genome shotgun sequence.
ACCESSION   DAUNLR010000119 DAUNLR010000000
VERSION     DAUNLR010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN30816728
            Sequence Read Archive: SRR21541897
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-FEB-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001640077.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001640077.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/23/2023 17:01:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,785
            CDSs (total)                      :: 1,743
            Genes (coding)                    :: 1,698
            CDSs (with protein)               :: 1,698
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 31 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 10 of 45
            Pseudo Genes (multiple problems)  :: 13 of 45
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN30816728-rid17249933.denovo.119"
                     /serotype="EMM44.0"
                     /isolate="NS5139"
                     /isolation_source="throat"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="Australia: Northern Territory"
                     /lat_lon="19.4914 S 132.5510 E"
                     /collection_date="2005-05-24"
                     /collected_by="Menzies School of Health Research, Charles
                     Darwin University"
                     /note="genotype: ST178"
     gene            complement(81..154)
                     /locus_tag="VLL59_001782"
     tRNA            complement(81..154)
                     /locus_tag="VLL59_001782"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(118..120),aa:Met,seq:cat)
     gene            complement(164..253)
                     /locus_tag="VLL59_001783"
     tRNA            complement(164..253)
                     /locus_tag="VLL59_001783"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(215..217),aa:Ser,seq:tga)
     gene            complement(276..349)
                     /locus_tag="VLL59_001784"
     tRNA            complement(276..349)
                     /locus_tag="VLL59_001784"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(313..315),aa:Ile,seq:cat)
     gene            complement(370..443)
                     /locus_tag="VLL59_001785"
     tRNA            complement(370..443)
                     /locus_tag="VLL59_001785"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(407..409),aa:Met,seq:cat)
BASE COUNT          120 a          127 c          101 g           96 t
ORIGIN      
        1 aatcgaaccg ccgacacatg gagcttcaat ccattgctct accaactgag ctaccgagcc
       61 aacaactaca tacttatgta ttgcgggagc aggatttgaa cctacgacct tcgggttatg
      121 agcccgacga gctacctaac tgctccatcc cgcgatagtt aaaaggagga tgtgggattc
      181 gaacccacgc acgcttttac acgcctgacg gttttcaaga ccgttccctt cagccggact
      241 tgggtaatcc tccaaaataa tgattatcta tgatatggac cttgtaggac tcgaacctac
      301 gaccgctcgg ttatgagccg agtgctctaa ccagttgagc taaaggtccc aagtcatcca
      361 taaaaataat agcggcgaag gggatcgaac ccccgacctc ccgggtatga accggacgct
      421 ctagccagct gagctacacc gcca
//
